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Search of human proteins with 20127642
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20127642 G kinase anchoring protein 1 isoform a [Homo
sapiens]
(366 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20127642 G kinase anchoring protein 1 isoform a [Homo sapiens] 720 0.0
gi|209915617 G kinase anchoring protein 1 isoform b [Homo sapiens] 591 e-169
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 54 2e-07
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 54 2e-07
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 54 2e-07
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 54 2e-07
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 54 3e-07
gi|156104908 myosin heavy chain 6 [Homo sapiens] 53 4e-07
gi|95147555 microtubule-associated protein 1A [Homo sapiens] 52 8e-07
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 51 2e-06
gi|109134347 NY-REN-58 antigen [Homo sapiens] 51 2e-06
gi|109134355 NY-REN-58 antigen [Homo sapiens] 51 2e-06
gi|237858621 polyamine modulated factor 1 binding protein 1 isof... 50 2e-06
gi|237858619 polyamine modulated factor 1 binding protein 1 isof... 50 2e-06
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 50 2e-06
gi|147905592 coiled-coil domain containing 102B [Homo sapiens] 50 2e-06
gi|148233522 coiled-coil domain containing 102B [Homo sapiens] 50 2e-06
gi|41872583 Rho-associated, coiled-coil containing protein kinas... 50 4e-06
gi|4885583 Rho-associated, coiled-coil containing protein kinase... 49 9e-06
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 49 9e-06
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 48 1e-05
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 48 1e-05
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 48 1e-05
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 48 1e-05
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 48 1e-05
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 48 1e-05
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 48 1e-05
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 48 1e-05
gi|15149463 caldesmon 1 isoform 4 [Homo sapiens] 48 1e-05
gi|15149467 caldesmon 1 isoform 3 [Homo sapiens] 48 1e-05
>gi|20127642 G kinase anchoring protein 1 isoform a [Homo sapiens]
Length = 366
Score = 720 bits (1859), Expect = 0.0
Identities = 366/366 (100%), Positives = 366/366 (100%)
Query: 1 MASAVLSSVPTTASRFALLQVDSGSGSDSEPGKGKGRNTGKSQTLGSKSTTNEKKREKRR 60
MASAVLSSVPTTASRFALLQVDSGSGSDSEPGKGKGRNTGKSQTLGSKSTTNEKKREKRR
Sbjct: 1 MASAVLSSVPTTASRFALLQVDSGSGSDSEPGKGKGRNTGKSQTLGSKSTTNEKKREKRR 60
Query: 61 KKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHDLPLSNPVQKDSREENWQEWRQRDEQ 120
KKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHDLPLSNPVQKDSREENWQEWRQRDEQ
Sbjct: 61 KKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHDLPLSNPVQKDSREENWQEWRQRDEQ 120
Query: 121 LTSEMFEADLEKALLLSKLEYEEHKKEYEDAENTSTQSKVMNKKDKRKNHQGKDRPLTVS 180
LTSEMFEADLEKALLLSKLEYEEHKKEYEDAENTSTQSKVMNKKDKRKNHQGKDRPLTVS
Sbjct: 121 LTSEMFEADLEKALLLSKLEYEEHKKEYEDAENTSTQSKVMNKKDKRKNHQGKDRPLTVS 180
Query: 181 LKDFHSEDHISKKTEELSSSQTLSHDGGFFNRLEDDVHKILIREKRREQLTEYNGTDNCT 240
LKDFHSEDHISKKTEELSSSQTLSHDGGFFNRLEDDVHKILIREKRREQLTEYNGTDNCT
Sbjct: 181 LKDFHSEDHISKKTEELSSSQTLSHDGGFFNRLEDDVHKILIREKRREQLTEYNGTDNCT 240
Query: 241 AHEHNQEVVLKDGRIERLKLELERKDAEIQKLKNVITQWEAKYKEVKARNAQLLKMLQEG 300
AHEHNQEVVLKDGRIERLKLELERKDAEIQKLKNVITQWEAKYKEVKARNAQLLKMLQEG
Sbjct: 241 AHEHNQEVVLKDGRIERLKLELERKDAEIQKLKNVITQWEAKYKEVKARNAQLLKMLQEG 300
Query: 301 EMKDKAEILLQVDESQSIKNELTIQVTSLHAALEQERSKVKVLQAELAKYQGGRKGKRNS 360
EMKDKAEILLQVDESQSIKNELTIQVTSLHAALEQERSKVKVLQAELAKYQGGRKGKRNS
Sbjct: 301 EMKDKAEILLQVDESQSIKNELTIQVTSLHAALEQERSKVKVLQAELAKYQGGRKGKRNS 360
Query: 361 ESDQCR 366
ESDQCR
Sbjct: 361 ESDQCR 366
>gi|209915617 G kinase anchoring protein 1 isoform b [Homo sapiens]
Length = 315
Score = 591 bits (1524), Expect = e-169
Identities = 315/366 (86%), Positives = 315/366 (86%), Gaps = 51/366 (13%)
Query: 1 MASAVLSSVPTTASRFALLQVDSGSGSDSEPGKGKGRNTGKSQTLGSKSTTNEKKREKRR 60
MASAVLSSVPTTASRFALLQVDSGSGSDSEPGKGKGRNTGKSQTLGSKSTTNEKKREKRR
Sbjct: 1 MASAVLSSVPTTASRFALLQVDSGSGSDSEPGKGKGRNTGKSQTLGSKSTTNEKKREKRR 60
Query: 61 KKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHDLPLSNPVQKDSREENWQEWRQRDEQ 120
KKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHDLPLSNPVQKDSREENWQEWRQRDEQ
Sbjct: 61 KKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHDLPLSNPVQKDSREENWQEWRQRDEQ 120
Query: 121 LTSEMFEADLEKALLLSKLEYEEHKKEYEDAENTSTQSKVMNKKDKRKNHQGKDRPLTVS 180
LTSEMFEADLEKALLLSKLEYEEHKKEYEDAENTSTQSKVMNKKDKRKNHQGKDRPLTVS
Sbjct: 121 LTSEMFEADLEKALLLSKLEYEEHKKEYEDAENTSTQSKVMNKKDKRKNHQGKDRPLTVS 180
Query: 181 LKDFHSEDHISKKTEELSSSQTLSHDGGFFNRLEDDVHKILIREKRREQLTEYNGTDNCT 240
LKDFHSEDHISKKTEE
Sbjct: 181 LKDFHSEDHISKKTEE-------------------------------------------- 196
Query: 241 AHEHNQEVVLKDGRIERLKLELERKDAEIQKLKNVITQWEAKYKEVKARNAQLLKMLQEG 300
VVLKDGRIERLKLELERKDAEIQKLKNVITQWEAKYKEVKARNAQLLKMLQEG
Sbjct: 197 -------VVLKDGRIERLKLELERKDAEIQKLKNVITQWEAKYKEVKARNAQLLKMLQEG 249
Query: 301 EMKDKAEILLQVDESQSIKNELTIQVTSLHAALEQERSKVKVLQAELAKYQGGRKGKRNS 360
EMKDKAEILLQVDESQSIKNELTIQVTSLHAALEQERSKVKVLQAELAKYQGGRKGKRNS
Sbjct: 250 EMKDKAEILLQVDESQSIKNELTIQVTSLHAALEQERSKVKVLQAELAKYQGGRKGKRNS 309
Query: 361 ESDQCR 366
ESDQCR
Sbjct: 310 ESDQCR 315
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 53.9 bits (128), Expect = 2e-07
Identities = 66/313 (21%), Positives = 138/313 (44%), Gaps = 38/313 (12%)
Query: 48 KSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHDLPLSNPVQKDSR 107
K+ ++K E K+ EQ+ S+ E +NL +++ Q + A+ ++ + +K
Sbjct: 863 KTKERQQKAENELKELEQKHSQLTEEKNLLQEQL-QAETELYAEAE-EMRVRLAAKKQEL 920
Query: 108 EE-------NWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHKKEYEDAENTSTQSKV 160
EE +E R +QL +E + + L +LE EE ++ E + ++K+
Sbjct: 921 EEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKI 980
Query: 161 MNKKDK------RKNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSHD-GGFFNRL 213
+D+ + N K+R L E+ IS T L+ + + + N+
Sbjct: 981 KKLEDEILVMDDQNNKLSKERKLL--------EERISDLTTNLAEEEEKAKNLTKLKNKH 1032
Query: 214 EDDVHKILIR----EKRREQLTEYNGTDNCTAHEHNQEVVLKDGRIERLKLELERKDAEI 269
E + ++ +R EK R++L + A + ++++ +I LK++L +K+ E+
Sbjct: 1033 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEEL 1092
Query: 270 QKLKNVITQWEAKYKEVKARNAQLLKMLQ-EGEMKDKAEILLQVDESQSIKNELTIQVTS 328
Q + E+ +N L K+ + EG + D E +D ++ +N+ Q
Sbjct: 1093 QAALARLDD------EIAQKNNALKKIRELEGHISDLQE---DLDSERAARNKAEKQKRD 1143
Query: 329 LHAALEQERSKVK 341
L LE +++++
Sbjct: 1144 LGEELEALKTELE 1156
Score = 48.9 bits (115), Expect = 7e-06
Identities = 65/338 (19%), Positives = 142/338 (42%), Gaps = 26/338 (7%)
Query: 45 LGSKSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHDLPLSNPVQK 104
L ++ NE+KR + +++ + ++E + R + + + + DL L
Sbjct: 1580 LQARDEQNEEKRRQLQRQLHEYETELEDERKQ--RALAAAAKKKLEGDLKDLELQADSAI 1637
Query: 105 DSREENWQEWRQRDEQLTSEMFEADLEKA------LLLSKLEYEEHKKEYED-----AEN 153
REE ++ R+ Q+ F+ +LE A + + E E+ K E E+
Sbjct: 1638 KGREEAIKQLRKLQAQMKD--FQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQED 1695
Query: 154 TSTQSKVMNKKDKRKNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNRL 213
+ + + D K ++ ++S ++ ++ + + L + G +
Sbjct: 1696 LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1755
Query: 214 EDDVHKILIREKRREQLTEYNGTDNCTAHEHNQEVVLKDGRIERLKLELERKDAEIQ-KL 272
D V K ++ EQL+ T+ TA ++ + + + L+ +L + ++ K
Sbjct: 1756 SDRVRKAT---QQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKF 1812
Query: 273 KNVITQWEAKYKEVKARNAQLLKMLQEG----EMKDKA--EILLQVDESQSIKNELTIQV 326
K+ I EAK +++ + Q + Q + KDK EILLQV++ + + + Q
Sbjct: 1813 KSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQA 1872
Query: 327 TSLHAALEQERSKVKVLQAELAKYQGGRKGKRNSESDQ 364
+A ++Q + +++ + E + R+ K E D+
Sbjct: 1873 EKGNARVKQLKRQLEEAEEESQRINANRR-KLQRELDE 1909
Score = 40.4 bits (93), Expect = 0.003
Identities = 28/102 (27%), Positives = 57/102 (55%), Gaps = 6/102 (5%)
Query: 254 RIERLKLELERKDAEIQKLKNVITQWEAKYKEVKARNAQLL--KMLQEGEMKDKAEILLQ 311
++ R + E++ K+ E+QK K + E + KE++ +++QL K L + +++ + E+ +
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905
Query: 312 VDESQ----SIKNELTIQVTSLHAALEQERSKVKVLQAELAK 349
+E + + K EL + + A LE+E + + LQAE K
Sbjct: 906 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKK 947
Score = 39.3 bits (90), Expect = 0.006
Identities = 79/359 (22%), Positives = 145/359 (40%), Gaps = 42/359 (11%)
Query: 20 QVDSGSGSDSEPGKGKGRNTGK------SQTLGSKSTTNEKKREKRR--KKKEQQQSEAN 71
+V+S +G +E +GK K SQ ++ E+ R+K K Q + E N
Sbjct: 1288 EVESVTGMLNE-AEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERN 1346
Query: 72 ELRNLAFKKIPQKSSHAVCNAQHDLPLSNPVQK----DSREENWQEWRQRDEQLTSEMFE 127
L++ +++ K + + ++ LS+ +K S E +E ++R ++ + +
Sbjct: 1347 SLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQ 1406
Query: 128 ADLEKALLLSKLEYEEHKKEYE------DAENTSTQSKVMNKKDKRKNHQGKDRPLTVSL 181
EKA KLE +++ + E D +N + KK +RK Q +S
Sbjct: 1407 QYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKK-QRKFDQLLAEEKNISS 1465
Query: 182 KDFHSEDHIS-----KKTEELSSSQTLSHDGGFFNRLEDDVHKILIREKRREQLTEYNGT 236
K D K+T+ LS ++ L LE +K+L E E L
Sbjct: 1466 KYADERDRAEAEAREKETKALSLARALEEALEAKEELER-TNKMLKAEM--EDLVSSKDD 1522
Query: 237 DNCTAHEHNQEVVLKDGRIERLKLELERKDAEIQKLKNVITQWEAKYKEVKARNAQLLKM 296
HE + + ++E +K +LE + E+Q ++ + E N Q LK
Sbjct: 1523 VGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEV--------NMQALKG 1574
Query: 297 LQEGEMKDKAEILLQVDESQSIKNELTIQVTSLHAALEQERSKVKVLQAELAKYQGGRK 355
E +++ + E +++ + +L Q+ LE ER + + A K +G K
Sbjct: 1575 QFERDLQARDE------QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLK 1627
Score = 29.3 bits (64), Expect = 5.8
Identities = 60/329 (18%), Positives = 130/329 (39%), Gaps = 30/329 (9%)
Query: 41 KSQTLGSKSTTNEKKREKRRKKKEQQQ-SEANELRNLAFKKIPQKSSHAVCNAQHDLPLS 99
+ + + SK + E ++KE + S A L K + ++ + A+ + +S
Sbjct: 1459 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVS 1518
Query: 100 NPVQKDSREENWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHKKEYEDAENTSTQSK 159
+ KD +N E + L ++M E + L +L+ E K + + + +
Sbjct: 1519 S---KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQ 1575
Query: 160 VMNKKDKR-KNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNRLEDDVH 218
R + ++ K R L L ++ +E +K L+++ +LE D+
Sbjct: 1576 FERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAK--------KKLEGDLK 1627
Query: 219 KILIREKRREQLTEYNGTDNCTAHEHNQEVVLKDGRIERLKLELERKDAEIQKLKNVITQ 278
+ ++ + G + + +KD + E +DA + + T
Sbjct: 1628 DLELQAD-----SAIKGREEAIKQLRKLQAQMKD-------FQRELEDARASRDEIFAT- 1674
Query: 279 WEAKYKEVKARNAQLLKMLQEGEMKDKAEILLQVD-ESQSIKNELTIQVTSLHAALEQER 337
AK E KA++ + M + ++ Q D E + + EL ++ + AL+ E+
Sbjct: 1675 --AKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRN-ALQDEK 1731
Query: 338 SKVKVLQAELAKYQGGRKGKRNSESDQCR 366
+++ A+L + +G + SD+ R
Sbjct: 1732 RRLEARIAQLEEELEEEQGNMEAMSDRVR 1760
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 53.9 bits (128), Expect = 2e-07
Identities = 66/313 (21%), Positives = 138/313 (44%), Gaps = 38/313 (12%)
Query: 48 KSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHDLPLSNPVQKDSR 107
K+ ++K E K+ EQ+ S+ E +NL +++ Q + A+ ++ + +K
Sbjct: 870 KTKERQQKAENELKELEQKHSQLTEEKNLLQEQL-QAETELYAEAE-EMRVRLAAKKQEL 927
Query: 108 EE-------NWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHKKEYEDAENTSTQSKV 160
EE +E R +QL +E + + L +LE EE ++ E + ++K+
Sbjct: 928 EEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKI 987
Query: 161 MNKKDK------RKNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSHD-GGFFNRL 213
+D+ + N K+R L E+ IS T L+ + + + N+
Sbjct: 988 KKLEDEILVMDDQNNKLSKERKLL--------EERISDLTTNLAEEEEKAKNLTKLKNKH 1039
Query: 214 EDDVHKILIR----EKRREQLTEYNGTDNCTAHEHNQEVVLKDGRIERLKLELERKDAEI 269
E + ++ +R EK R++L + A + ++++ +I LK++L +K+ E+
Sbjct: 1040 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEEL 1099
Query: 270 QKLKNVITQWEAKYKEVKARNAQLLKMLQ-EGEMKDKAEILLQVDESQSIKNELTIQVTS 328
Q + E+ +N L K+ + EG + D E +D ++ +N+ Q
Sbjct: 1100 QAALARLDD------EIAQKNNALKKIRELEGHISDLQE---DLDSERAARNKAEKQKRD 1150
Query: 329 LHAALEQERSKVK 341
L LE +++++
Sbjct: 1151 LGEELEALKTELE 1163
Score = 48.9 bits (115), Expect = 7e-06
Identities = 65/338 (19%), Positives = 142/338 (42%), Gaps = 26/338 (7%)
Query: 45 LGSKSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHDLPLSNPVQK 104
L ++ NE+KR + +++ + ++E + R + + + + DL L
Sbjct: 1587 LQARDEQNEEKRRQLQRQLHEYETELEDERKQ--RALAAAAKKKLEGDLKDLELQADSAI 1644
Query: 105 DSREENWQEWRQRDEQLTSEMFEADLEKA------LLLSKLEYEEHKKEYED-----AEN 153
REE ++ R+ Q+ F+ +LE A + + E E+ K E E+
Sbjct: 1645 KGREEAIKQLRKLQAQMKD--FQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQED 1702
Query: 154 TSTQSKVMNKKDKRKNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNRL 213
+ + + D K ++ ++S ++ ++ + + L + G +
Sbjct: 1703 LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1762
Query: 214 EDDVHKILIREKRREQLTEYNGTDNCTAHEHNQEVVLKDGRIERLKLELERKDAEIQ-KL 272
D V K ++ EQL+ T+ TA ++ + + + L+ +L + ++ K
Sbjct: 1763 SDRVRKAT---QQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKF 1819
Query: 273 KNVITQWEAKYKEVKARNAQLLKMLQEG----EMKDKA--EILLQVDESQSIKNELTIQV 326
K+ I EAK +++ + Q + Q + KDK EILLQV++ + + + Q
Sbjct: 1820 KSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQA 1879
Query: 327 TSLHAALEQERSKVKVLQAELAKYQGGRKGKRNSESDQ 364
+A ++Q + +++ + E + R+ K E D+
Sbjct: 1880 EKGNARVKQLKRQLEEAEEESQRINANRR-KLQRELDE 1916
Score = 40.4 bits (93), Expect = 0.003
Identities = 28/102 (27%), Positives = 57/102 (55%), Gaps = 6/102 (5%)
Query: 254 RIERLKLELERKDAEIQKLKNVITQWEAKYKEVKARNAQLL--KMLQEGEMKDKAEILLQ 311
++ R + E++ K+ E+QK K + E + KE++ +++QL K L + +++ + E+ +
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 912
Query: 312 VDESQ----SIKNELTIQVTSLHAALEQERSKVKVLQAELAK 349
+E + + K EL + + A LE+E + + LQAE K
Sbjct: 913 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKK 954
Score = 39.3 bits (90), Expect = 0.006
Identities = 79/359 (22%), Positives = 145/359 (40%), Gaps = 42/359 (11%)
Query: 20 QVDSGSGSDSEPGKGKGRNTGK------SQTLGSKSTTNEKKREKRR--KKKEQQQSEAN 71
+V+S +G +E +GK K SQ ++ E+ R+K K Q + E N
Sbjct: 1295 EVESVTGMLNE-AEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERN 1353
Query: 72 ELRNLAFKKIPQKSSHAVCNAQHDLPLSNPVQK----DSREENWQEWRQRDEQLTSEMFE 127
L++ +++ K + + ++ LS+ +K S E +E ++R ++ + +
Sbjct: 1354 SLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQ 1413
Query: 128 ADLEKALLLSKLEYEEHKKEYE------DAENTSTQSKVMNKKDKRKNHQGKDRPLTVSL 181
EKA KLE +++ + E D +N + KK +RK Q +S
Sbjct: 1414 QYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKK-QRKFDQLLAEEKNISS 1472
Query: 182 KDFHSEDHIS-----KKTEELSSSQTLSHDGGFFNRLEDDVHKILIREKRREQLTEYNGT 236
K D K+T+ LS ++ L LE +K+L E E L
Sbjct: 1473 KYADERDRAEAEAREKETKALSLARALEEALEAKEELER-TNKMLKAEM--EDLVSSKDD 1529
Query: 237 DNCTAHEHNQEVVLKDGRIERLKLELERKDAEIQKLKNVITQWEAKYKEVKARNAQLLKM 296
HE + + ++E +K +LE + E+Q ++ + E N Q LK
Sbjct: 1530 VGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEV--------NMQALKG 1581
Query: 297 LQEGEMKDKAEILLQVDESQSIKNELTIQVTSLHAALEQERSKVKVLQAELAKYQGGRK 355
E +++ + E +++ + +L Q+ LE ER + + A K +G K
Sbjct: 1582 QFERDLQARDE------QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLK 1634
Score = 29.3 bits (64), Expect = 5.8
Identities = 60/329 (18%), Positives = 130/329 (39%), Gaps = 30/329 (9%)
Query: 41 KSQTLGSKSTTNEKKREKRRKKKEQQQ-SEANELRNLAFKKIPQKSSHAVCNAQHDLPLS 99
+ + + SK + E ++KE + S A L K + ++ + A+ + +S
Sbjct: 1466 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVS 1525
Query: 100 NPVQKDSREENWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHKKEYEDAENTSTQSK 159
+ KD +N E + L ++M E + L +L+ E K + + + +
Sbjct: 1526 S---KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQ 1582
Query: 160 VMNKKDKR-KNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNRLEDDVH 218
R + ++ K R L L ++ +E +K L+++ +LE D+
Sbjct: 1583 FERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAK--------KKLEGDLK 1634
Query: 219 KILIREKRREQLTEYNGTDNCTAHEHNQEVVLKDGRIERLKLELERKDAEIQKLKNVITQ 278
+ ++ + G + + +KD + E +DA + + T
Sbjct: 1635 DLELQAD-----SAIKGREEAIKQLRKLQAQMKD-------FQRELEDARASRDEIFAT- 1681
Query: 279 WEAKYKEVKARNAQLLKMLQEGEMKDKAEILLQVD-ESQSIKNELTIQVTSLHAALEQER 337
AK E KA++ + M + ++ Q D E + + EL ++ + AL+ E+
Sbjct: 1682 --AKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRN-ALQDEK 1738
Query: 338 SKVKVLQAELAKYQGGRKGKRNSESDQCR 366
+++ A+L + +G + SD+ R
Sbjct: 1739 RRLEARIAQLEEELEEEQGNMEAMSDRVR 1767
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 53.9 bits (128), Expect = 2e-07
Identities = 66/313 (21%), Positives = 138/313 (44%), Gaps = 38/313 (12%)
Query: 48 KSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHDLPLSNPVQKDSR 107
K+ ++K E K+ EQ+ S+ E +NL +++ Q + A+ ++ + +K
Sbjct: 870 KTKERQQKAENELKELEQKHSQLTEEKNLLQEQL-QAETELYAEAE-EMRVRLAAKKQEL 927
Query: 108 EE-------NWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHKKEYEDAENTSTQSKV 160
EE +E R +QL +E + + L +LE EE ++ E + ++K+
Sbjct: 928 EEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKI 987
Query: 161 MNKKDK------RKNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSHD-GGFFNRL 213
+D+ + N K+R L E+ IS T L+ + + + N+
Sbjct: 988 KKLEDEILVMDDQNNKLSKERKLL--------EERISDLTTNLAEEEEKAKNLTKLKNKH 1039
Query: 214 EDDVHKILIR----EKRREQLTEYNGTDNCTAHEHNQEVVLKDGRIERLKLELERKDAEI 269
E + ++ +R EK R++L + A + ++++ +I LK++L +K+ E+
Sbjct: 1040 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEEL 1099
Query: 270 QKLKNVITQWEAKYKEVKARNAQLLKMLQ-EGEMKDKAEILLQVDESQSIKNELTIQVTS 328
Q + E+ +N L K+ + EG + D E +D ++ +N+ Q
Sbjct: 1100 QAALARLDD------EIAQKNNALKKIRELEGHISDLQE---DLDSERAARNKAEKQKRD 1150
Query: 329 LHAALEQERSKVK 341
L LE +++++
Sbjct: 1151 LGEELEALKTELE 1163
Score = 48.9 bits (115), Expect = 7e-06
Identities = 65/338 (19%), Positives = 142/338 (42%), Gaps = 26/338 (7%)
Query: 45 LGSKSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHDLPLSNPVQK 104
L ++ NE+KR + +++ + ++E + R + + + + DL L
Sbjct: 1587 LQARDEQNEEKRRQLQRQLHEYETELEDERKQ--RALAAAAKKKLEGDLKDLELQADSAI 1644
Query: 105 DSREENWQEWRQRDEQLTSEMFEADLEKA------LLLSKLEYEEHKKEYED-----AEN 153
REE ++ R+ Q+ F+ +LE A + + E E+ K E E+
Sbjct: 1645 KGREEAIKQLRKLQAQMKD--FQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQED 1702
Query: 154 TSTQSKVMNKKDKRKNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNRL 213
+ + + D K ++ ++S ++ ++ + + L + G +
Sbjct: 1703 LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1762
Query: 214 EDDVHKILIREKRREQLTEYNGTDNCTAHEHNQEVVLKDGRIERLKLELERKDAEIQ-KL 272
D V K ++ EQL+ T+ TA ++ + + + L+ +L + ++ K
Sbjct: 1763 SDRVRKAT---QQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKF 1819
Query: 273 KNVITQWEAKYKEVKARNAQLLKMLQEG----EMKDKA--EILLQVDESQSIKNELTIQV 326
K+ I EAK +++ + Q + Q + KDK EILLQV++ + + + Q
Sbjct: 1820 KSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQA 1879
Query: 327 TSLHAALEQERSKVKVLQAELAKYQGGRKGKRNSESDQ 364
+A ++Q + +++ + E + R+ K E D+
Sbjct: 1880 EKGNARVKQLKRQLEEAEEESQRINANRR-KLQRELDE 1916
Score = 40.4 bits (93), Expect = 0.003
Identities = 28/102 (27%), Positives = 57/102 (55%), Gaps = 6/102 (5%)
Query: 254 RIERLKLELERKDAEIQKLKNVITQWEAKYKEVKARNAQLL--KMLQEGEMKDKAEILLQ 311
++ R + E++ K+ E+QK K + E + KE++ +++QL K L + +++ + E+ +
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 912
Query: 312 VDESQ----SIKNELTIQVTSLHAALEQERSKVKVLQAELAK 349
+E + + K EL + + A LE+E + + LQAE K
Sbjct: 913 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKK 954
Score = 39.3 bits (90), Expect = 0.006
Identities = 79/359 (22%), Positives = 145/359 (40%), Gaps = 42/359 (11%)
Query: 20 QVDSGSGSDSEPGKGKGRNTGK------SQTLGSKSTTNEKKREKRR--KKKEQQQSEAN 71
+V+S +G +E +GK K SQ ++ E+ R+K K Q + E N
Sbjct: 1295 EVESVTGMLNE-AEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERN 1353
Query: 72 ELRNLAFKKIPQKSSHAVCNAQHDLPLSNPVQK----DSREENWQEWRQRDEQLTSEMFE 127
L++ +++ K + + ++ LS+ +K S E +E ++R ++ + +
Sbjct: 1354 SLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQ 1413
Query: 128 ADLEKALLLSKLEYEEHKKEYE------DAENTSTQSKVMNKKDKRKNHQGKDRPLTVSL 181
EKA KLE +++ + E D +N + KK +RK Q +S
Sbjct: 1414 QYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKK-QRKFDQLLAEEKNISS 1472
Query: 182 KDFHSEDHIS-----KKTEELSSSQTLSHDGGFFNRLEDDVHKILIREKRREQLTEYNGT 236
K D K+T+ LS ++ L LE +K+L E E L
Sbjct: 1473 KYADERDRAEAEAREKETKALSLARALEEALEAKEELER-TNKMLKAEM--EDLVSSKDD 1529
Query: 237 DNCTAHEHNQEVVLKDGRIERLKLELERKDAEIQKLKNVITQWEAKYKEVKARNAQLLKM 296
HE + + ++E +K +LE + E+Q ++ + E N Q LK
Sbjct: 1530 VGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEV--------NMQALKG 1581
Query: 297 LQEGEMKDKAEILLQVDESQSIKNELTIQVTSLHAALEQERSKVKVLQAELAKYQGGRK 355
E +++ + E +++ + +L Q+ LE ER + + A K +G K
Sbjct: 1582 QFERDLQARDE------QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLK 1634
Score = 29.3 bits (64), Expect = 5.8
Identities = 60/329 (18%), Positives = 130/329 (39%), Gaps = 30/329 (9%)
Query: 41 KSQTLGSKSTTNEKKREKRRKKKEQQQ-SEANELRNLAFKKIPQKSSHAVCNAQHDLPLS 99
+ + + SK + E ++KE + S A L K + ++ + A+ + +S
Sbjct: 1466 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVS 1525
Query: 100 NPVQKDSREENWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHKKEYEDAENTSTQSK 159
+ KD +N E + L ++M E + L +L+ E K + + + +
Sbjct: 1526 S---KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQ 1582
Query: 160 VMNKKDKR-KNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNRLEDDVH 218
R + ++ K R L L ++ +E +K L+++ +LE D+
Sbjct: 1583 FERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAK--------KKLEGDLK 1634
Query: 219 KILIREKRREQLTEYNGTDNCTAHEHNQEVVLKDGRIERLKLELERKDAEIQKLKNVITQ 278
+ ++ + G + + +KD + E +DA + + T
Sbjct: 1635 DLELQAD-----SAIKGREEAIKQLRKLQAQMKD-------FQRELEDARASRDEIFAT- 1681
Query: 279 WEAKYKEVKARNAQLLKMLQEGEMKDKAEILLQVD-ESQSIKNELTIQVTSLHAALEQER 337
AK E KA++ + M + ++ Q D E + + EL ++ + AL+ E+
Sbjct: 1682 --AKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRN-ALQDEK 1738
Query: 338 SKVKVLQAELAKYQGGRKGKRNSESDQCR 366
+++ A+L + +G + SD+ R
Sbjct: 1739 RRLEARIAQLEEELEEEQGNMEAMSDRVR 1767
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 53.9 bits (128), Expect = 2e-07
Identities = 66/313 (21%), Positives = 138/313 (44%), Gaps = 38/313 (12%)
Query: 48 KSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHDLPLSNPVQKDSR 107
K+ ++K E K+ EQ+ S+ E +NL +++ Q + A+ ++ + +K
Sbjct: 863 KTKERQQKAENELKELEQKHSQLTEEKNLLQEQL-QAETELYAEAE-EMRVRLAAKKQEL 920
Query: 108 EE-------NWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHKKEYEDAENTSTQSKV 160
EE +E R +QL +E + + L +LE EE ++ E + ++K+
Sbjct: 921 EEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKI 980
Query: 161 MNKKDK------RKNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSHD-GGFFNRL 213
+D+ + N K+R L E+ IS T L+ + + + N+
Sbjct: 981 KKLEDEILVMDDQNNKLSKERKLL--------EERISDLTTNLAEEEEKAKNLTKLKNKH 1032
Query: 214 EDDVHKILIR----EKRREQLTEYNGTDNCTAHEHNQEVVLKDGRIERLKLELERKDAEI 269
E + ++ +R EK R++L + A + ++++ +I LK++L +K+ E+
Sbjct: 1033 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEEL 1092
Query: 270 QKLKNVITQWEAKYKEVKARNAQLLKMLQ-EGEMKDKAEILLQVDESQSIKNELTIQVTS 328
Q + E+ +N L K+ + EG + D E +D ++ +N+ Q
Sbjct: 1093 QAALARLDD------EIAQKNNALKKIRELEGHISDLQE---DLDSERAARNKAEKQKRD 1143
Query: 329 LHAALEQERSKVK 341
L LE +++++
Sbjct: 1144 LGEELEALKTELE 1156
Score = 48.9 bits (115), Expect = 7e-06
Identities = 65/338 (19%), Positives = 142/338 (42%), Gaps = 26/338 (7%)
Query: 45 LGSKSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHDLPLSNPVQK 104
L ++ NE+KR + +++ + ++E + R + + + + DL L
Sbjct: 1580 LQARDEQNEEKRRQLQRQLHEYETELEDERKQ--RALAAAAKKKLEGDLKDLELQADSAI 1637
Query: 105 DSREENWQEWRQRDEQLTSEMFEADLEKA------LLLSKLEYEEHKKEYED-----AEN 153
REE ++ R+ Q+ F+ +LE A + + E E+ K E E+
Sbjct: 1638 KGREEAIKQLRKLQAQMKD--FQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQED 1695
Query: 154 TSTQSKVMNKKDKRKNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNRL 213
+ + + D K ++ ++S ++ ++ + + L + G +
Sbjct: 1696 LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1755
Query: 214 EDDVHKILIREKRREQLTEYNGTDNCTAHEHNQEVVLKDGRIERLKLELERKDAEIQ-KL 272
D V K ++ EQL+ T+ TA ++ + + + L+ +L + ++ K
Sbjct: 1756 SDRVRKAT---QQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKF 1812
Query: 273 KNVITQWEAKYKEVKARNAQLLKMLQEG----EMKDKA--EILLQVDESQSIKNELTIQV 326
K+ I EAK +++ + Q + Q + KDK EILLQV++ + + + Q
Sbjct: 1813 KSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQA 1872
Query: 327 TSLHAALEQERSKVKVLQAELAKYQGGRKGKRNSESDQ 364
+A ++Q + +++ + E + R+ K E D+
Sbjct: 1873 EKGNARVKQLKRQLEEAEEESQRINANRR-KLQRELDE 1909
Score = 40.4 bits (93), Expect = 0.003
Identities = 28/102 (27%), Positives = 57/102 (55%), Gaps = 6/102 (5%)
Query: 254 RIERLKLELERKDAEIQKLKNVITQWEAKYKEVKARNAQLL--KMLQEGEMKDKAEILLQ 311
++ R + E++ K+ E+QK K + E + KE++ +++QL K L + +++ + E+ +
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905
Query: 312 VDESQ----SIKNELTIQVTSLHAALEQERSKVKVLQAELAK 349
+E + + K EL + + A LE+E + + LQAE K
Sbjct: 906 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKK 947
Score = 39.3 bits (90), Expect = 0.006
Identities = 79/359 (22%), Positives = 145/359 (40%), Gaps = 42/359 (11%)
Query: 20 QVDSGSGSDSEPGKGKGRNTGK------SQTLGSKSTTNEKKREKRR--KKKEQQQSEAN 71
+V+S +G +E +GK K SQ ++ E+ R+K K Q + E N
Sbjct: 1288 EVESVTGMLNE-AEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERN 1346
Query: 72 ELRNLAFKKIPQKSSHAVCNAQHDLPLSNPVQK----DSREENWQEWRQRDEQLTSEMFE 127
L++ +++ K + + ++ LS+ +K S E +E ++R ++ + +
Sbjct: 1347 SLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQ 1406
Query: 128 ADLEKALLLSKLEYEEHKKEYE------DAENTSTQSKVMNKKDKRKNHQGKDRPLTVSL 181
EKA KLE +++ + E D +N + KK +RK Q +S
Sbjct: 1407 QYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKK-QRKFDQLLAEEKNISS 1465
Query: 182 KDFHSEDHIS-----KKTEELSSSQTLSHDGGFFNRLEDDVHKILIREKRREQLTEYNGT 236
K D K+T+ LS ++ L LE +K+L E E L
Sbjct: 1466 KYADERDRAEAEAREKETKALSLARALEEALEAKEELER-TNKMLKAEM--EDLVSSKDD 1522
Query: 237 DNCTAHEHNQEVVLKDGRIERLKLELERKDAEIQKLKNVITQWEAKYKEVKARNAQLLKM 296
HE + + ++E +K +LE + E+Q ++ + E N Q LK
Sbjct: 1523 VGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEV--------NMQALKG 1574
Query: 297 LQEGEMKDKAEILLQVDESQSIKNELTIQVTSLHAALEQERSKVKVLQAELAKYQGGRK 355
E +++ + E +++ + +L Q+ LE ER + + A K +G K
Sbjct: 1575 QFERDLQARDE------QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLK 1627
Score = 29.3 bits (64), Expect = 5.8
Identities = 60/329 (18%), Positives = 130/329 (39%), Gaps = 30/329 (9%)
Query: 41 KSQTLGSKSTTNEKKREKRRKKKEQQQ-SEANELRNLAFKKIPQKSSHAVCNAQHDLPLS 99
+ + + SK + E ++KE + S A L K + ++ + A+ + +S
Sbjct: 1459 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVS 1518
Query: 100 NPVQKDSREENWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHKKEYEDAENTSTQSK 159
+ KD +N E + L ++M E + L +L+ E K + + + +
Sbjct: 1519 S---KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQ 1575
Query: 160 VMNKKDKR-KNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNRLEDDVH 218
R + ++ K R L L ++ +E +K L+++ +LE D+
Sbjct: 1576 FERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAK--------KKLEGDLK 1627
Query: 219 KILIREKRREQLTEYNGTDNCTAHEHNQEVVLKDGRIERLKLELERKDAEIQKLKNVITQ 278
+ ++ + G + + +KD + E +DA + + T
Sbjct: 1628 DLELQAD-----SAIKGREEAIKQLRKLQAQMKD-------FQRELEDARASRDEIFAT- 1674
Query: 279 WEAKYKEVKARNAQLLKMLQEGEMKDKAEILLQVD-ESQSIKNELTIQVTSLHAALEQER 337
AK E KA++ + M + ++ Q D E + + EL ++ + AL+ E+
Sbjct: 1675 --AKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRN-ALQDEK 1731
Query: 338 SKVKVLQAELAKYQGGRKGKRNSESDQCR 366
+++ A+L + +G + SD+ R
Sbjct: 1732 RRLEARIAQLEEELEEEQGNMEAMSDRVR 1760
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 53.5 bits (127), Expect = 3e-07
Identities = 77/359 (21%), Positives = 147/359 (40%), Gaps = 42/359 (11%)
Query: 27 SDSEPGKGKGRNTGKSQTLGSKSTTNEKKREKRRKKKEQ-------QQSEANELRNLAFK 79
++ E K R +SQ +++ +K R+ + KE+ +Q+ N + A +
Sbjct: 690 AEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQ 749
Query: 80 KIPQ------KSSHAVCNAQHDLPLSNPVQK-DSREENWQEWRQRDEQLTSEMFEADLEK 132
++ + K + A +H L +++ Q+ Q + EA L+K
Sbjct: 750 QLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQK 809
Query: 133 ALLLSKLEYEEHKKEYEDAENTSTQSKVMNKKDKRKNHQGKDRPLTVSLKDFHSEDHISK 192
L ++E+ H+K Y A S ++ ++KR+ +G+ +K+ H +
Sbjct: 810 CL--GQVEHRVHQKSYHVAGYEHELSSLL--REKRQEVEGEHERRLDKMKEEHQQVMAKA 865
Query: 193 KT-----EELSSSQTLSHDGGFFNRLEDDVHKILIREKRREQLTEYNGTDNCTAHEHNQE 247
+ E ++ L H G RL+ H+ + R+EQ + ++ QE
Sbjct: 866 REQYEAEERKQRAELLGHLTGELERLQR-AHERELETVRQEQ---HKRLEDLRRRHREQE 921
Query: 248 VVLKD-------------GRIERLKLELERKDAEIQKLKNVITQWEAKYKEVKARNAQLL 294
L+D R+ L+++ E E Q+L +V Q K +E A + QL
Sbjct: 922 RKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLE 981
Query: 295 KMLQEGE--MKDKAEILLQVDESQSIKNELTIQVTSLHAALEQERSKVKVLQAELAKYQ 351
+ +E ++ ++ +DE Q+ K +L QV L A +Q + L+AE K Q
Sbjct: 982 EAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQ 1040
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 53.1 bits (126), Expect = 4e-07
Identities = 67/314 (21%), Positives = 137/314 (43%), Gaps = 36/314 (11%)
Query: 41 KSQTLGSKSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHDLPLSN 100
K +T + T ++ +K+ ++ Q EA E N + +K+ H + N DL +
Sbjct: 1376 KYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSL-EKTKHRLQNEIEDLMVD- 1433
Query: 101 PVQKDSREENWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHKKEYEDAENTSTQSKV 160
V++ + + +QR+ +K L K +YEE + E E ++ +
Sbjct: 1434 -VERSNAAAAALDKKQRN-----------FDKILAEWKQKYEESQSELESSQKEARSLST 1481
Query: 161 MNKKDKRKNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNRLEDDVHKI 220
K K + + T ++ + ++ IS TE+L +GG +VH++
Sbjct: 1482 ELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLG-------EGG------KNVHEL 1528
Query: 221 LIREKRREQLTEYNGTDNCTAHEHNQEVVLKDGRIERLKLELERKDAEIQKLKNVITQWE 280
EK R+QL E + ++G+I R +LE + AEI++ + + +
Sbjct: 1529 ---EKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERK---LAEKD 1582
Query: 281 AKYKEVKARNAQLLKMLQ---EGEMKDKAEILLQVDESQSIKNELTIQVTSLHAALEQER 337
+ ++ K + +++ LQ + E + + E+L + + NE+ IQ++ + + +
Sbjct: 1583 EEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQ 1642
Query: 338 SKVKVLQAELAKYQ 351
+VK LQ+ L Q
Sbjct: 1643 KQVKSLQSLLKDTQ 1656
Score = 35.0 bits (79), Expect = 0.11
Identities = 59/277 (21%), Positives = 123/277 (44%), Gaps = 30/277 (10%)
Query: 53 EKKREKRRKKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHDLPLSNPVQ-KDSREENW 111
+KK E + E Q S AN + A K++ KS ++ + L + V+ D +EN
Sbjct: 1617 KKKMEGDLNEMEIQLSHANRMAAEAQKQV--KSLQSLLK-DTQIQLDDAVRANDDLKENI 1673
Query: 112 QEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHKKEYEDAENTSTQSKVMNKKDKRKNHQ 171
+R+ L +E+ E L + +E E ++ + E T +V + +
Sbjct: 1674 AIVERRNNLLQAELEE-------LRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLI 1726
Query: 172 GKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNRLEDDVHKILIREKRREQLT 231
+ + + L SE + + +E +++ + + D ++ E ++EQ T
Sbjct: 1727 NQKKKMESDLTQLQSE--VEEAVQECRNAEEKAKKA-----ITDAA--MMAEELKKEQDT 1777
Query: 232 EYNGTDNCTAHEHNQEVVLKDGRI---ERLKLELERKDAEIQKLKNVITQWEAKYKEVKA 288
+ + + N E +KD + E ++ L+ ++QKL+ + + E + + +
Sbjct: 1778 ----SAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQK 1833
Query: 289 RNAQLLKMLQEGEMKDKAEILLQVDESQSIKNELTIQ 325
RNA+ +K +++ E + K E+ Q +E + KN L +Q
Sbjct: 1834 RNAESVKGMRKSERRIK-ELTYQTEEDK--KNLLRLQ 1867
Score = 28.5 bits (62), Expect = 9.9
Identities = 27/109 (24%), Positives = 53/109 (48%), Gaps = 9/109 (8%)
Query: 249 VLKDGRIERLKLELERKDAEIQKLKNVITQWEAKYKEVKARNAQLLKMLQEGEMKDKAE- 307
+LK E+ E+ E ++K + + EA+ KE++ + LL+ + +++ +AE
Sbjct: 841 LLKSAETEK---EMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQ 897
Query: 308 -ILLQVDE--SQSIKNELTIQ--VTSLHAALEQERSKVKVLQAELAKYQ 351
L +E Q IKN++ ++ V ++ LE E L A+ K +
Sbjct: 898 DNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLE 946
>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
Length = 2803
Score = 52.0 bits (123), Expect = 8e-07
Identities = 65/318 (20%), Positives = 128/318 (40%), Gaps = 42/318 (13%)
Query: 46 GSKSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHDLPLSNPV--- 102
G K T+E+K+E K + QQ + + L K++ + A+ L + N
Sbjct: 1348 GLKDRTSEQKKEPEPKDEVLQQKD----KTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQ 1403
Query: 103 QKDSREENWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHKKEYEDAEN-TSTQSKVM 161
Q + E+ ++ Q+D L + +KAL + EE K E + + K +
Sbjct: 1404 QDKALEQKGRDLEQKDTALEQK------DKALEPKDKDLEEKDKALEQKDKIPEEKDKAL 1457
Query: 162 NKKDKRKNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNRLEDDVHKIL 221
+KD + KD+ L KD +D + ++ E++ + + D
Sbjct: 1458 EQKDTAL--EQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALD--------------- 1500
Query: 222 IREKRREQLTEYNGTDNCTAHEHNQEVVLKDGRIERLKLELERKDAEIQKLKNVITQ--W 279
++ + E+ ++ A ++++ D E+ E+KD +K + Q W
Sbjct: 1501 ----QKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYW 1556
Query: 280 EAKYKEVKARNAQLLKMLQEGEMKDKAEILLQVDESQS---IKNELTIQVTSLHAALEQE 336
K+ Q ++ L+E + E L+Q D+++ ++ + +V ++ LE
Sbjct: 1557 ALGQKDEALE--QNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEAL 1614
Query: 337 RSKVKVLQAELAKYQGGR 354
K K L E + Q GR
Sbjct: 1615 LEKTKALGLEESLVQEGR 1632
Score = 28.9 bits (63), Expect = 7.6
Identities = 38/157 (24%), Positives = 66/157 (42%), Gaps = 8/157 (5%)
Query: 20 QVDSGSGS---DSEPGKGKGRNTGKSQTLGSKSTTNEKKREKRRKKKEQQQSEANELRNL 76
Q D SG+ + +P K K R K ++L + + T K KR + E+ EA
Sbjct: 296 QKDLASGAVPTNLKPSKIKQRADSK-ESLKATTKTAVSKLAKREEVVEEGAKEARSELAK 354
Query: 77 AFKKIPQKSSHAVCNAQHDLPLSNPVQKDSREENWQEWRQ--RDEQLTSEMFE--ADLEK 132
K +K+ + V+ +S E E R+ +D+ + E + LE+
Sbjct: 355 ELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEE 414
Query: 133 ALLLSKLEYEEHKKEYEDAENTSTQSKVMNKKDKRKN 169
K E ++ +KE + E + K K++KRK+
Sbjct: 415 KKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKD 451
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 50.8 bits (120), Expect = 2e-06
Identities = 64/347 (18%), Positives = 150/347 (43%), Gaps = 38/347 (10%)
Query: 41 KSQTLGSKSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHDLPLSN 100
K++T+ TN+ RE++ + ++ Q ++R L +P + ++A + + +
Sbjct: 1265 KTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGM---L 1321
Query: 101 PVQKDSREENWQEWRQRDEQLTSEMFEADLEK-ALLLSKLEYEEHKKEYEDAENTSTQSK 159
+K EE+ + W+ R++ L S+ + D E+ LLS+ E + + E +++
Sbjct: 1322 QAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAE 1381
Query: 160 VMNKKDKRKNHQGKDRPLTVSLKDFHSE------DHISKKTEELSSSQTLSHDGGFFNRL 213
+ N+Q + L L +E D +K + +T++ R
Sbjct: 1382 IARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRY 1441
Query: 214 EDDVHKILIREKRREQLTEYNGTDNCTAHEHNQEV-VLK-------------DGRIERLK 259
+ ++ ++ + + + + D+ H QE+ LK + ++E L+
Sbjct: 1442 KTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQ 1501
Query: 260 LELERKDAEIQKLKNVITQWEAKYKEVK-------ARNAQLLKMLQEGEMKDKAEILL-- 310
L K+ E + L+ Q +++ ++ + QL + + E E K + I+
Sbjct: 1502 KTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAK 1561
Query: 311 -QVDESQSIKNELTIQVTSL---HAALEQERSKVKV-LQAELAKYQG 352
++ +K++LT + L + AL+Q++ ++ V + A ++Y+G
Sbjct: 1562 SKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQYEG 1608
Score = 42.0 bits (97), Expect = 9e-04
Identities = 79/331 (23%), Positives = 140/331 (42%), Gaps = 48/331 (14%)
Query: 65 QQQSEANELRNLAFKKIPQKSSHAVCNAQHDLPLSNPVQKDSREENWQEWRQRDEQL--- 121
QQ E EL L K + K + + Q ++ + + E+ Q++ + +++L
Sbjct: 6 QQVLERTELNKLP-KSVQNKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHS 64
Query: 122 -------TSEMFEADLEKALLLSKLE-YEEHKKEYEDAENTS-------TQSKVMNKKDK 166
T E LE L ++L+ E KE E A++ + T++K + +K
Sbjct: 65 QERLVNETRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEK 124
Query: 167 RKNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGF-FNRLEDDVHKILIREK 225
R + +R L+ L ++ +ED + + E+L S T + + L+ + REK
Sbjct: 125 RDLIRTNER-LSQEL-EYLTED-VKRLNEKLKESNTTKGELQLKLDELQASDVSVKYREK 181
Query: 226 RREQLTEYNGTDNC---TAHEHNQEVVLKDGR-----IERLKLELERKDAEIQKLKNVIT 277
R EQ E + N T + + +L GR I LK LE K E+ +L+ +
Sbjct: 182 RLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMN 241
Query: 278 QWEAKYKEVKARNAQLLKMLQEGE-----MKDK------AEILLQ------VDESQSIKN 320
+ + ++ LL L+E + M++K A I L D+S++ N
Sbjct: 242 GLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSN 301
Query: 321 ELTIQVTSLHAALEQERSKVKVLQAELAKYQ 351
ELT V LH L++ K +Q L + +
Sbjct: 302 ELTRAVEELHKLLKEAGEANKAIQDHLLEVE 332
Score = 30.4 bits (67), Expect = 2.6
Identities = 58/333 (17%), Positives = 136/333 (40%), Gaps = 38/333 (11%)
Query: 48 KSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIPQKSSH---AVCNAQHDLPLSNPVQK 104
+S + + EK+ + E+++ E + + A + + Q+ S + + Q+++ +Q+
Sbjct: 996 ESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEV--QEALQR 1053
Query: 105 DSREENWQEWRQRDEQLTSEMF---EADLEKALLLSKLEYEEHKKEYEDAENTSTQSKVM 161
S + ++ +RD Q +++ + E+ L+L + E + E ++ + +
Sbjct: 1054 ASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHL 1113
Query: 162 NKKDKRKNHQGKDRPLTVSLKDFHSEDHISK---KTEELSSSQTLSHDG----------- 207
+ ++ Q + + ++ +D +SK + E+L L HD
Sbjct: 1114 EETTQKAESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVAS 1173
Query: 208 ------GFFN-------RLEDDVHKILIREKRREQLTEYN-GTDNCTAHEHNQEVVLKDG 253
G N + ++ + +IL +R +++ E + + Q V L +
Sbjct: 1174 VKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLER 1233
Query: 254 RIERLKLELERKDAEIQKLKNVITQWEAKYKEVKARNAQLLKMLQEGEMKDKAEILLQVD 313
++ L+ L + ++Q + Q E K+ + N + E K++ E LQ
Sbjct: 1234 ELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQ-- 1291
Query: 314 ESQSIKNELTIQVTSLHAALEQERSKVKVLQAE 346
+ Q+ +L + + L A + K +LQAE
Sbjct: 1292 QMQAKVRKLELDILPLQEANAELSEKSGMLQAE 1324
>gi|109134347 NY-REN-58 antigen [Homo sapiens]
Length = 701
Score = 50.8 bits (120), Expect = 2e-06
Identities = 71/329 (21%), Positives = 134/329 (40%), Gaps = 38/329 (11%)
Query: 41 KSQTLGSKSTTNEKKREKRRKKKEQ--QQSEANELRNLAFKKIPQKSSHAVCNAQHDLPL 98
++Q L T + K+ E+ ++K Q+ + E K + S V NAQ + +
Sbjct: 195 RNQLLNVDLTKDSKRVEQLAREKVYLCQKLKGLEAEVAELKAEKENSEAQVENAQR-IQV 253
Query: 99 SNPVQKD----SREENWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHKKEYEDAENT 154
+ S E Q R E+L E+ + + L++KL HK E E
Sbjct: 254 RQLAEMQATVRSLEAEKQSANLRAERLEKELQSSSEQNTFLINKL----HKAERE----- 304
Query: 155 STQSKVMNKKDKRKNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNRLE 214
++ K K H K + L+ ++ + ++ ++ S +
Sbjct: 305 ---INTLSSKVKELKHSNKLEITDIKLETARAKSELERERNKIQSELDGLQSDNEILKAA 361
Query: 215 DDVHKILIREKRREQLTEYNGTDNCTAHEHNQEVVLKDGRIERLKLELERKDAEIQKLKN 274
+ HK+L+ EK RE + + + + VVL+D KLELE + A+++K+K
Sbjct: 362 VEHHKVLLVEKDRELIRKVQAAKE---EGYQKLVVLQDE-----KLELENRLADLEKMKV 413
Query: 275 VITQWEAKYKEVKARNAQLLKMLQEGEMKDKAEILLQVDESQSIKNELTIQVTSLHAALE 334
W K+ + +M +E K E QS++ +L Q+ ++ A E
Sbjct: 414 EHDVWRQSEKDQYEEKLRASQMAEEITRK----------ELQSVRLKLQQQIVTIENA-E 462
Query: 335 QERSKVKVLQAELAKYQGGRKGKRNSESD 363
+E+++ L+ +++ Q SE+D
Sbjct: 463 KEKNENSDLKQQISSLQIQVTSLAQSEND 491
Score = 40.4 bits (93), Expect = 0.003
Identities = 58/252 (23%), Positives = 120/252 (47%), Gaps = 52/252 (20%)
Query: 127 EADLEKALLLSKLEYEEHKKEYED--AENTSTQSKVMNKKDKRKN----HQGKDRPLTVS 180
+++ +K L+ +L E HK Y+ AE+T Q++ + +++ K+ Q + L +
Sbjct: 28 QSEFQKMLIDERLRCEHHKANYQTLKAEHTRLQNEHVKLQNELKHLFNEKQTQQEKLQLL 87
Query: 181 LKDFHSEDHISKKTEELSSS--QTLSHDGGFFNRLEDDVHKILIREKRREQLTEYNGTDN 238
L++ E + +KT++L Q L+ +LE L+R + +++L
Sbjct: 88 LEELRGE--LVEKTKDLEEMKLQILTPQ-----KLE------LLRAQIQQEL-------- 126
Query: 239 CTAHEHNQEVVLKDGRIERLKLELERKDAEIQKLKNVITQWEAKYKEVKARNAQLLKMLQ 298
E +++ R L E+E+ A KL+ T +++++ K A++L
Sbjct: 127 --------ETPMRE-RFRNLDEEVEKYRAVYNKLRYEHTFLKSEFEHQKEEYARIL---D 174
Query: 299 EGEMKDKAEILLQVDESQSIKNE-LTIQVTSLHAALEQER-------SKVKVLQAELAKY 350
EG++K ++EI ++ + ++N+ L + +T +EQ K+K L+AE+A+
Sbjct: 175 EGKIKYESEIARLEEDKEELRNQLLNVDLTKDSKRVEQLAREKVYLCQKLKGLEAEVAEL 234
Query: 351 QGGRKGKRNSES 362
+ K NSE+
Sbjct: 235 ---KAEKENSEA 243
>gi|109134355 NY-REN-58 antigen [Homo sapiens]
Length = 701
Score = 50.8 bits (120), Expect = 2e-06
Identities = 71/329 (21%), Positives = 134/329 (40%), Gaps = 38/329 (11%)
Query: 41 KSQTLGSKSTTNEKKREKRRKKKEQ--QQSEANELRNLAFKKIPQKSSHAVCNAQHDLPL 98
++Q L T + K+ E+ ++K Q+ + E K + S V NAQ + +
Sbjct: 195 RNQLLNVDLTKDSKRVEQLAREKVYLCQKLKGLEAEVAELKAEKENSEAQVENAQR-IQV 253
Query: 99 SNPVQKD----SREENWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHKKEYEDAENT 154
+ S E Q R E+L E+ + + L++KL HK E E
Sbjct: 254 RQLAEMQATVRSLEAEKQSANLRAERLEKELQSSSEQNTFLINKL----HKAERE----- 304
Query: 155 STQSKVMNKKDKRKNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNRLE 214
++ K K H K + L+ ++ + ++ ++ S +
Sbjct: 305 ---INTLSSKVKELKHSNKLEITDIKLETARAKSELERERNKIQSELDGLQSDNEILKAA 361
Query: 215 DDVHKILIREKRREQLTEYNGTDNCTAHEHNQEVVLKDGRIERLKLELERKDAEIQKLKN 274
+ HK+L+ EK RE + + + + VVL+D KLELE + A+++K+K
Sbjct: 362 VEHHKVLLVEKDRELIRKVQAAKE---EGYQKLVVLQDE-----KLELENRLADLEKMKV 413
Query: 275 VITQWEAKYKEVKARNAQLLKMLQEGEMKDKAEILLQVDESQSIKNELTIQVTSLHAALE 334
W K+ + +M +E K E QS++ +L Q+ ++ A E
Sbjct: 414 EHDVWRQSEKDQYEEKLRASQMAEEITRK----------ELQSVRLKLQQQIVTIENA-E 462
Query: 335 QERSKVKVLQAELAKYQGGRKGKRNSESD 363
+E+++ L+ +++ Q SE+D
Sbjct: 463 KEKNENSDLKQQISSLQIQVTSLAQSEND 491
Score = 40.4 bits (93), Expect = 0.003
Identities = 58/252 (23%), Positives = 120/252 (47%), Gaps = 52/252 (20%)
Query: 127 EADLEKALLLSKLEYEEHKKEYED--AENTSTQSKVMNKKDKRKN----HQGKDRPLTVS 180
+++ +K L+ +L E HK Y+ AE+T Q++ + +++ K+ Q + L +
Sbjct: 28 QSEFQKMLIDERLRCEHHKANYQTLKAEHTRLQNEHVKLQNELKHLFNEKQTQQEKLQLL 87
Query: 181 LKDFHSEDHISKKTEELSSS--QTLSHDGGFFNRLEDDVHKILIREKRREQLTEYNGTDN 238
L++ E + +KT++L Q L+ +LE L+R + +++L
Sbjct: 88 LEELRGE--LVEKTKDLEEMKLQILTPQ-----KLE------LLRAQIQQEL-------- 126
Query: 239 CTAHEHNQEVVLKDGRIERLKLELERKDAEIQKLKNVITQWEAKYKEVKARNAQLLKMLQ 298
E +++ R L E+E+ A KL+ T +++++ K A++L
Sbjct: 127 --------ETPMRE-RFRNLDEEVEKYRAVYNKLRYEHTFLKSEFEHQKEEYARIL---D 174
Query: 299 EGEMKDKAEILLQVDESQSIKNE-LTIQVTSLHAALEQER-------SKVKVLQAELAKY 350
EG++K ++EI ++ + ++N+ L + +T +EQ K+K L+AE+A+
Sbjct: 175 EGKIKYESEIARLEEDKEELRNQLLNVDLTKDSKRVEQLAREKVYLCQKLKGLEAEVAEL 234
Query: 351 QGGRKGKRNSES 362
+ K NSE+
Sbjct: 235 ---KAEKENSEA 243
>gi|237858621 polyamine modulated factor 1 binding protein 1 isoform
b [Homo sapiens]
Length = 882
Score = 50.4 bits (119), Expect = 2e-06
Identities = 74/339 (21%), Positives = 141/339 (41%), Gaps = 53/339 (15%)
Query: 43 QTLGSKSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHDLPLSNPV 102
Q L K T + K+ K+ E+QQ A EL + KS A C A L V
Sbjct: 266 QELEKKLTQVQNSLLKKEKELEKQQCMATELEMTVKEAKQDKSKEAECKA-----LQAEV 320
Query: 103 Q--KDSREENWQEWRQRDEQLTS------------EMFEADLEKALLLSKLEYEEHKKEY 148
Q K+S EE Q+ R +Q E + L+K LLL K + + ++
Sbjct: 321 QKLKNSLEEAKQQERLAAQQAAQCKEEAALAGCHLEDTQRKLQKGLLLDKQKADTIQELQ 380
Query: 149 EDAENTSTQSKVMNKK--DKRKNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLS-- 204
+ + +S + K+ RK + L+ +L+ + D ++ ++ + Q +
Sbjct: 381 RELQMLQKESSMAEKEQTSNRKRVEELSLELSEALRKLENSDKEKRQLQKTVAEQDMKMN 440
Query: 205 -----------HDGGFFNRLEDDVHKIL-IREKRREQLTEYNGTDNCTAHEHNQEVVLKD 252
G +LE+D+ + + E +REQL + + EH + L +
Sbjct: 441 DMLDRIKHQHREQGSIKCKLEEDLQEATKLLEDKREQLKK--------SKEHEK---LME 489
Query: 253 GRIERLKLELERKDAEIQKLKNVITQWEAKYK-EVKARNAQLLKMLQEGEMKDKAEILLQ 311
G +E L+ E ++KD +++ + + + E++ + QL L + +++
Sbjct: 490 GELEALRQEFKKKDKTLKENSRKLEEENENLRAELQCCSTQLESSL--NKYNTSQQVIQD 547
Query: 312 VDESQSIKNELTIQVTSLHAALEQERSKVK-VLQAELAK 349
+++ +++ E + SL A L++ K K LQ + K
Sbjct: 548 LNKEIALQKE---SLMSLQAQLDKALQKEKHYLQTTITK 583
Score = 31.2 bits (69), Expect = 1.5
Identities = 31/121 (25%), Positives = 55/121 (45%), Gaps = 12/121 (9%)
Query: 253 GRIERLKLELERKDAEIQKLKNVITQWEAKYKEVKARNAQLLKMLQE-GEMKDKAEILLQ 311
G E +ERKD +I L+ + + + ++ E + + K LQE EM + E L
Sbjct: 214 GLREETSAHIERKDKDITILQCRLQELQLEFTETQKLTLKKDKFLQEKDEMLQELEKKLT 273
Query: 312 VDESQSIKNELTIQ-----VTSLHAAL---EQERSK---VKVLQAELAKYQGGRKGKRNS 360
++ +K E ++ T L + +Q++SK K LQAE+ K + + +
Sbjct: 274 QVQNSLLKKEKELEKQQCMATELEMTVKEAKQDKSKEAECKALQAEVQKLKNSLEEAKQQ 333
Query: 361 E 361
E
Sbjct: 334 E 334
>gi|237858619 polyamine modulated factor 1 binding protein 1 isoform
a [Homo sapiens]
Length = 1007
Score = 50.4 bits (119), Expect = 2e-06
Identities = 74/339 (21%), Positives = 141/339 (41%), Gaps = 53/339 (15%)
Query: 43 QTLGSKSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHDLPLSNPV 102
Q L K T + K+ K+ E+QQ A EL + KS A C A L V
Sbjct: 411 QELEKKLTQVQNSLLKKEKELEKQQCMATELEMTVKEAKQDKSKEAECKA-----LQAEV 465
Query: 103 Q--KDSREENWQEWRQRDEQLTS------------EMFEADLEKALLLSKLEYEEHKKEY 148
Q K+S EE Q+ R +Q E + L+K LLL K + + ++
Sbjct: 466 QKLKNSLEEAKQQERLAAQQAAQCKEEAALAGCHLEDTQRKLQKGLLLDKQKADTIQELQ 525
Query: 149 EDAENTSTQSKVMNKK--DKRKNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLS-- 204
+ + +S + K+ RK + L+ +L+ + D ++ ++ + Q +
Sbjct: 526 RELQMLQKESSMAEKEQTSNRKRVEELSLELSEALRKLENSDKEKRQLQKTVAEQDMKMN 585
Query: 205 -----------HDGGFFNRLEDDVHKIL-IREKRREQLTEYNGTDNCTAHEHNQEVVLKD 252
G +LE+D+ + + E +REQL + + EH + L +
Sbjct: 586 DMLDRIKHQHREQGSIKCKLEEDLQEATKLLEDKREQLKK--------SKEHEK---LME 634
Query: 253 GRIERLKLELERKDAEIQKLKNVITQWEAKYK-EVKARNAQLLKMLQEGEMKDKAEILLQ 311
G +E L+ E ++KD +++ + + + E++ + QL L + +++
Sbjct: 635 GELEALRQEFKKKDKTLKENSRKLEEENENLRAELQCCSTQLESSL--NKYNTSQQVIQD 692
Query: 312 VDESQSIKNELTIQVTSLHAALEQERSKVK-VLQAELAK 349
+++ +++ E + SL A L++ K K LQ + K
Sbjct: 693 LNKEIALQKE---SLMSLQAQLDKALQKEKHYLQTTITK 728
Score = 31.2 bits (69), Expect = 1.5
Identities = 31/121 (25%), Positives = 55/121 (45%), Gaps = 12/121 (9%)
Query: 253 GRIERLKLELERKDAEIQKLKNVITQWEAKYKEVKARNAQLLKMLQE-GEMKDKAEILLQ 311
G E +ERKD +I L+ + + + ++ E + + K LQE EM + E L
Sbjct: 359 GLREETSAHIERKDKDITILQCRLQELQLEFTETQKLTLKKDKFLQEKDEMLQELEKKLT 418
Query: 312 VDESQSIKNELTIQ-----VTSLHAAL---EQERSK---VKVLQAELAKYQGGRKGKRNS 360
++ +K E ++ T L + +Q++SK K LQAE+ K + + +
Sbjct: 419 QVQNSLLKKEKELEKQQCMATELEMTVKEAKQDKSKEAECKALQAEVQKLKNSLEEAKQQ 478
Query: 361 E 361
E
Sbjct: 479 E 479
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 50.4 bits (119), Expect = 2e-06
Identities = 68/304 (22%), Positives = 133/304 (43%), Gaps = 33/304 (10%)
Query: 53 EKKREKRRKKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHDLPLSNPVQKDSREENWQ 112
E ++E K++ ++++ R+ A +K ++ ++ ++DL L Q S EN
Sbjct: 848 EAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQL----QVQSETENLM 903
Query: 113 EWRQRDEQLTSEMFEADLEKALLLSKLEYEEHKKEYEDAENTSTQSKVMNKKDKRKNHQG 172
+ +R E L K LL +K++ + E E+ N+ +K N +DK + +
Sbjct: 904 DAEERCEGLIKS-------KILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKR 956
Query: 173 KDRPLTVSLKDFHSEDHISK-KTEELSSSQTLSHDGGFFNRLEDDVHKILIREKRREQLT 231
L ++L E H ++ K + LS T LE+++ K L +EK+ Q
Sbjct: 957 DIDDLELTLTKVEKEKHATENKVKNLSEEMT---------ALEENISK-LTKEKKSLQEA 1006
Query: 232 EYNGTDNCTAHEHNQEVVLK-DGRIERLKLELERKDAEIQKLKNVITQWEAKYKEVKARN 290
D+ E ++K + ++E+ +LE + +KL+ A + K +
Sbjct: 1007 HQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLR-------ADLERAKRKL 1059
Query: 291 AQLLKMLQEGEM---KDKAEILLQVDESQSIKNELTIQVTSLHAALEQERSKVKVLQAEL 347
LKM QE M DK +I ++ + + ++L ++ Q + K+K LQA +
Sbjct: 1060 EGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARI 1119
Query: 348 AKYQ 351
+ +
Sbjct: 1120 EELE 1123
Score = 40.4 bits (93), Expect = 0.003
Identities = 72/357 (20%), Positives = 146/357 (40%), Gaps = 68/357 (19%)
Query: 45 LGSKSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHDLPLSNPVQK 104
LG + ++ ++K K+K + + E +++ + KS+ +++
Sbjct: 1207 LGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSN---------------IER 1251
Query: 105 DSR--EENWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHK-KEYEDAENTSTQSK-- 159
R E+ + E + +DEQ T + + +++KA L ++ H+ +E E + T+SK
Sbjct: 1252 TCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQA 1311
Query: 160 ----------VMNKKDKRKNHQG----KDRPLTVSLKDFHSEDH---------ISKKTEE 196
M ++ K KN R L++ + E+ +SK E
Sbjct: 1312 LTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSE 1371
Query: 197 LSSSQTLSHDGGF--FNRLEDDVHKILIREKRREQLTEYNGTDNCTAHEHNQEVVLKDGR 254
++ +T LE+ K+ R + E+ TE C + E ++ + G
Sbjct: 1372 VAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTE-TANSKCASLEKTKQRL--QGE 1428
Query: 255 IERLKLELERK-------DAEIQKLKNVITQW-----------EAKYKEVKARNAQLLKM 296
+E L +LER D + + V+ +W EA KE ++ + +L KM
Sbjct: 1429 VEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKM 1488
Query: 297 LQE-GEMKDKAEILLQVDES-QSIKNELTIQVTSLHAALEQERSKVKVLQAELAKYQ 351
E+ D+ E L + +++ Q ++LT Q+ L++ K+++ E + Q
Sbjct: 1489 RNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQ 1545
Score = 38.5 bits (88), Expect = 0.010
Identities = 67/332 (20%), Positives = 131/332 (39%), Gaps = 46/332 (13%)
Query: 42 SQTLGSKSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIP-QKSSHAVCNAQHDLP--- 97
++ L + N + K+R +++ S ++ +L +K HA N +L
Sbjct: 927 TERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEM 986
Query: 98 --LSNPVQKDSREE-NWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHKKEYEDAENT 154
L + K ++E+ + QE Q + L E D L+ + E+ + E +
Sbjct: 987 TALEENISKLTKEKKSLQEAHQ--QTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQ 1044
Query: 155 STQSKVMNKKDKRKNHQGKDRPLTVSLKDFHS-----EDHISKKTEELSSSQTLSHDGGF 209
+ + ++ KRK +G + S+ D + E+ + KK ELS Q D
Sbjct: 1045 EKKLRADLERAKRKL-EGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDD--- 1100
Query: 210 FNRLEDDVHKILIREKRREQLTEYNGTDNCTAHEHNQEVVLKDGRIERLKLELERKDAEI 269
+ VH + ++K +E + EH +IE+ + +L R+ EI
Sbjct: 1101 -----EQVHSLQFQKKIKELQARIEELEEEIEAEHTLRA-----KIEKQRSDLARELEEI 1150
Query: 270 -QKLKNVITQWEAKYKEVKARNAQLLKM-----------------LQEGEMKDKAEILLQ 311
++L+ A+ + K R A+ KM L++ + AE+ Q
Sbjct: 1151 SERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQ 1210
Query: 312 VDESQSIKNELTIQVTSLHAALEQERSKVKVL 343
+D Q +K +L + + L ++ S ++ L
Sbjct: 1211 IDNLQRVKQKLEKEKSELKMEIDDMASNIEAL 1242
Score = 35.8 bits (81), Expect = 0.062
Identities = 75/346 (21%), Positives = 145/346 (41%), Gaps = 35/346 (10%)
Query: 28 DSEPGKGKGRNTGKSQTLGSKSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIPQKSSH 87
D E + K + ++ L S + R + K++ + + NE+ S+
Sbjct: 1584 DEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQL-----GHSNR 1638
Query: 88 AVCNAQHDLPLSNPVQKDSREENWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHKKE 147
+ Q L KDS + + + + +E L ++ + LLL +LE E K
Sbjct: 1639 QMAETQKHLRTVQGQLKDS-QLHLDDALRSNEDLKEQLAIVERRNGLLLEELE--EMKVA 1695
Query: 148 YEDAENTS--TQSKVMNKKDKRKNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSH 205
E E T ++ ++++ D+ + ++ L + K ++ + E S ++ +
Sbjct: 1696 LEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNA 1755
Query: 206 DGGFFNRLEDDVHKILIREKRREQLTEYNGTDNCTAHEHNQEVVLKDGRI---ERLKLEL 262
+ + D ++ E ++EQ T + + + N E +KD + E +L L
Sbjct: 1756 EEKAKKAITDAA--MMAEELKKEQDT----SAHLERMKKNLEQTVKDLQHRLDEAEQLAL 1809
Query: 263 ERKDAEIQKLKNVITQWEAKYKEVKARNAQLLKMLQEGEMKDKAEILLQVDESQSIKNEL 322
+ +IQKL+N + + E + + R A+ LK + E K K E+ Q +E KN L
Sbjct: 1810 KGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVK-EMTYQAEEDH--KNIL 1866
Query: 323 TIQ--VTSLHAALEQERSKVKVLQAELAKYQGGRKGKRNSESDQCR 366
+Q V L A ++ + QAE A+ Q N++ +CR
Sbjct: 1867 RLQDLVDKLQAKVKSYKR-----QAEEAEEQA------NTQLSRCR 1901
>gi|147905592 coiled-coil domain containing 102B [Homo sapiens]
Length = 513
Score = 50.4 bits (119), Expect = 2e-06
Identities = 68/288 (23%), Positives = 122/288 (42%), Gaps = 54/288 (18%)
Query: 95 DLPLSNPVQKDS----REENWQE--WRQRDEQLTSEMFEADLEKALLLSKLEYEEHK--- 145
+LPL N V + S + +Q+ W++R+ + E LE AL L K +YEE K
Sbjct: 247 NLPLENEVTEISALQVHLDEFQKILWKEREMRTALEKEIERLESALSLWKWKYEELKESK 306
Query: 146 ----KEYE---DAENTSTQSKVMNKKDKRKNHQGKDR---PLTVSLKDFHSEDHISKKTE 195
KE++ N Q N K++ K+ KDR L L+ +E+ T
Sbjct: 307 PKNVKEFDILLGQHNDEMQELSGNIKEESKSQNSKDRVICELRAELERLQAEN-----TS 361
Query: 196 ELSSSQTLSHDGGFFNRLEDDVHKILIREKRREQLTEYNGTDNCTAH------------E 243
E + L + LE + ++ I+ K E+L + + + E
Sbjct: 362 EWDKREILEREK---QGLERENRRLKIQVKEMEELLDKKNRLSANSQSPDFKMSQIDLQE 418
Query: 244 HNQEVVLKDGRIERLKLELERKDAEIQKLKNVITQWEAKYKEVKARNAQLLKMLQEGEMK 303
NQE++ +L + + AE+ N + Q EA+ K+++ R +L + L + E
Sbjct: 419 KNQELLNLQHAYYKLNRQYQANIAELTHANNRVDQNEAEVKKLRLRVEELKQGLNQKED- 477
Query: 304 DKAEILLQVDESQSIKNELTIQVTSLHAALEQERSKVKVLQAELAKYQ 351
++D+S + Q+ L +L++E+ + + L+ EL Q
Sbjct: 478 -------ELDDSLN-------QIRKLQRSLDEEKERNENLETELRHLQ 511
>gi|148233522 coiled-coil domain containing 102B [Homo sapiens]
Length = 513
Score = 50.4 bits (119), Expect = 2e-06
Identities = 68/288 (23%), Positives = 122/288 (42%), Gaps = 54/288 (18%)
Query: 95 DLPLSNPVQKDS----REENWQE--WRQRDEQLTSEMFEADLEKALLLSKLEYEEHK--- 145
+LPL N V + S + +Q+ W++R+ + E LE AL L K +YEE K
Sbjct: 247 NLPLENEVTEISALQVHLDEFQKILWKEREMRTALEKEIERLESALSLWKWKYEELKESK 306
Query: 146 ----KEYE---DAENTSTQSKVMNKKDKRKNHQGKDR---PLTVSLKDFHSEDHISKKTE 195
KE++ N Q N K++ K+ KDR L L+ +E+ T
Sbjct: 307 PKNVKEFDILLGQHNDEMQELSGNIKEESKSQNSKDRVICELRAELERLQAEN-----TS 361
Query: 196 ELSSSQTLSHDGGFFNRLEDDVHKILIREKRREQLTEYNGTDNCTAH------------E 243
E + L + LE + ++ I+ K E+L + + + E
Sbjct: 362 EWDKREILEREK---QGLERENRRLKIQVKEMEELLDKKNRLSANSQSPDFKMSQIDLQE 418
Query: 244 HNQEVVLKDGRIERLKLELERKDAEIQKLKNVITQWEAKYKEVKARNAQLLKMLQEGEMK 303
NQE++ +L + + AE+ N + Q EA+ K+++ R +L + L + E
Sbjct: 419 KNQELLNLQHAYYKLNRQYQANIAELTHANNRVDQNEAEVKKLRLRVEELKQGLNQKED- 477
Query: 304 DKAEILLQVDESQSIKNELTIQVTSLHAALEQERSKVKVLQAELAKYQ 351
++D+S + Q+ L +L++E+ + + L+ EL Q
Sbjct: 478 -------ELDDSLN-------QIRKLQRSLDEEKERNENLETELRHLQ 511
>gi|41872583 Rho-associated, coiled-coil containing protein kinase 2
[Homo sapiens]
Length = 1388
Score = 49.7 bits (117), Expect = 4e-06
Identities = 65/304 (21%), Positives = 127/304 (41%), Gaps = 32/304 (10%)
Query: 61 KKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHDLPLSNPVQ-KDSREENWQEWRQRDE 119
++ + QS NE KK+ H LSN +Q K+ E+ + R E
Sbjct: 429 RETDSIQSRKNEESQEIQKKLYTLEEH----------LSNEMQAKEELEQKCKSVNTRLE 478
Query: 120 QLTSEMFEADLEKALLLSKLEYEEHKKEYEDAENTSTQSKVMNKKDKRKNHQGKDRPLTV 179
+ E+ E + + S L E +K +N Q K ++ DK++N + L
Sbjct: 479 KTAKELEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKD 538
Query: 180 SLKDFHSEDHISK-KTEELSSSQTLSHDGGFFNRLEDDVHKILIREKRREQLTEYNGTDN 238
L+D + S+ TE+++ Q + R E D +R+ + E + ++
Sbjct: 539 QLEDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDT-AARLRKTQAESSKQIQQLES 597
Query: 239 CTAHEHNQEVVLKDGRIERLKLELERKDAEIQKL-----------KNVITQWEAKY--KE 285
+N+++ K+ +E KL+LE++ +Q +I + + E
Sbjct: 598 -----NNRDLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRICGLE 652
Query: 286 VKARNAQLLKMLQEGEMKDKAEILLQVD-ESQSIKNELTIQVTSLHAALEQERSKVKVLQ 344
+N ++L E E + E ++ E +++ ++T Q+ + +LEQE ++ K +
Sbjct: 653 EDLKNGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATK 712
Query: 345 AELA 348
A LA
Sbjct: 713 ARLA 716
Score = 32.7 bits (73), Expect = 0.53
Identities = 58/302 (19%), Positives = 119/302 (39%), Gaps = 35/302 (11%)
Query: 54 KKREKRRKKKEQQQSEANE-LRNLAFKKIPQKSSHAVCNAQHDLPLSNPV-------QKD 105
K+ +++ + +Q+ NE +RNL K ++ + C Q+DL + +K
Sbjct: 769 KQSQQKINELLKQKDVLNEDVRNLTLKI--EQETQKRCLTQNDLKMQTQQVNTLKMSEKQ 826
Query: 106 SREEN------WQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHKKEYEDAENTSTQSK 159
++EN +++ +L E +AD + L +LE E++ TQ +
Sbjct: 827 LKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLY-----KTQVR 881
Query: 160 VMNKKDKRKNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNRLEDDVHK 219
+ ++ + K GK+ + K +D +L + T + + ++ +
Sbjct: 882 ELKEECEEKTKLGKE----LQQKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYS 937
Query: 220 ILIREKRREQLTEYNGTDNCTAHEHNQEVVLKDGRIERLKLELERKDAEIQKLKNVITQW 279
L +EK ++L H QE+ KD I L+ +++ L N +
Sbjct: 938 DLEKEKIMKELEIKE-----MMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEEL 992
Query: 280 EAKYKEVKARNAQLLKMLQEGEMKDKAEILLQVDESQSIKNELTIQVTSLHAALEQERSK 339
K K+V+ + ++L + E A I Q ++ + L Q + A + +
Sbjct: 993 NNKLKDVQEQLSRL-----KDEEISAAAIKAQFEKQLLTERTLKTQAVNKLAEIMNRKEP 1047
Query: 340 VK 341
VK
Sbjct: 1048 VK 1049
>gi|4885583 Rho-associated, coiled-coil containing protein kinase 1
[Homo sapiens]
Length = 1354
Score = 48.5 bits (114), Expect = 9e-06
Identities = 62/274 (22%), Positives = 120/274 (43%), Gaps = 17/274 (6%)
Query: 98 LSNPVQ-KDSREENWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHKKEYEDAENTST 156
L N +Q KD E+ + + +++ E+ E ++ L S + E +K
Sbjct: 439 LHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLESTVSQIEKEKMLLQHRINEY 498
Query: 157 QSKVMNKKDKRKNHQGKDRPLTVSLKDFHSEDHISK-KTEELSSSQTLSHDGGFFNRLED 215
Q K + +KR+N + + L L+D S+ E+LS Q + R E
Sbjct: 499 QRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKLSQLQKQLEEANDLLRTES 558
Query: 216 DVHKILIREKRREQLTEYNGTDNCTAHEHNQEVVLKDGRIERLK--------LELERKDA 267
D + +R+ E + ++ + +L++ + + K LE ER+D
Sbjct: 559 DT-AVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDR 617
Query: 268 --EIQKLKNVITQWEAKYKEVKARNAQLLKMLQEGEMKDKAEILLQVD-ESQSIKNELTI 324
+ + + ++ + + +EVK L K+ EGE K+ ++L + E +++ +L
Sbjct: 618 GHDSEMIGDLQARITSLQEEVKHLKHNLEKV--EGERKEAQDMLNHSEKEKNNLEIDLNY 675
Query: 325 QVTSLHAALEQERSKVKVLQAELA-KYQGGRKGK 357
++ SL LEQE ++ KV +A L K+Q + K
Sbjct: 676 KLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAK 709
Score = 48.1 bits (113), Expect = 1e-05
Identities = 57/249 (22%), Positives = 110/249 (44%), Gaps = 23/249 (9%)
Query: 104 KDSREENWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHKKEYEDAENTSTQSKVMNK 163
K +E +E +++ + ++ E EK L ++L+ E K E E + +
Sbjct: 857 KTQVKELKEEIEEKNRENLKKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQYFEL 916
Query: 164 KDKRKNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNRLEDDVHKILIR 223
+ K ++R ++ +DH + EE +S L+ D R +++ + + +
Sbjct: 917 TQESKKAASRNR------QEITDKDHTVSRLEEANSM--LTKDIEILRRENEELTEKMKK 968
Query: 224 EKRREQLTEYNGTDNCTA---HEHNQEVVLKDGRIERLKLELERKDAEIQKLKNVITQWE 280
+ +L + N A N E LK + +L + RKD +I + K TQ +
Sbjct: 969 AEEEYKLEKEEEISNLKAAFEKNINTERTLKTQAVNKLAEIMNRKDFKIDR-KKANTQ-D 1026
Query: 281 AKYKEVKARNAQLLKMLQEGE---------MKDKAEILLQVDESQSIKNELTIQVTSLHA 331
+ KE + R QL ++ QE E K+ ++ Q+ E + +NEL +Q+ S +
Sbjct: 1027 LRKKEKENRKLQL-ELNQEREKFNQMVVKHQKELNDMQAQLVEECAHRNELQMQLASKES 1085
Query: 332 ALEQERSKV 340
+EQ R+K+
Sbjct: 1086 DIEQLRAKL 1094
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 48.5 bits (114), Expect = 9e-06
Identities = 37/152 (24%), Positives = 70/152 (46%), Gaps = 24/152 (15%)
Query: 30 EPGKGKGRNTGKSQTLGSKSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIPQKSSHAV 89
E K + R GK + G + E++R+KRR++KE ++ E E R KK ++S
Sbjct: 72 EREKERKRERGKKEKKGERKK-EERERKKRRREKENKEGEEKEKRKKKEKKERGRTS--- 127
Query: 90 CNAQHDLPLSNPVQKDSREENWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHK---- 145
K+ +E +E R+R+E+ E + + EK + + E K
Sbjct: 128 --------------KEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGE 173
Query: 146 --KEYEDAENTSTQSKVMNKKDKRKNHQGKDR 175
+E ++ E + + N+K+++K + K+R
Sbjct: 174 KEEERKEKERKERKKRERNRKERKKERERKER 205
Score = 38.9 bits (89), Expect = 0.007
Identities = 48/244 (19%), Positives = 94/244 (38%), Gaps = 54/244 (22%)
Query: 46 GSKSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHDLPLSNPVQKD 105
G K +E+K+E+R ++K +++ E R +K+
Sbjct: 51 GKKERESERKKERREREKRKREREKERKRERG-------------------------KKE 85
Query: 106 SREENWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHKKEYEDAENTSTQSKVMNKKD 165
+ E +E R+R ++ + + EK + KKE ++ TS + K +K+
Sbjct: 86 KKGERKKEERERKKRRREKENKEGEEKE--------KRKKKEKKERGRTSKEGKERERKE 137
Query: 166 KRKNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNRLEDDVHKILIREK 225
+RK + K+R ++ E KK E + + E+ K K
Sbjct: 138 ERKREERKERERKKEEREKERERKERKKRERKQVGE----------KEEERKEKERKERK 187
Query: 226 RREQLTEYNGTDNCTAHEHNQEVVLKDGRIERLKLELERKDAEIQKLKNVITQWEAKYKE 285
+RE+ E +E K+ R ER K ++++ + ++ K+ T W K +
Sbjct: 188 KRER----------NRKERKKERERKERR-ERKKERKKKEERKKERQKDRQTNWREKERG 236
Query: 286 VKAR 289
+ R
Sbjct: 237 KRER 240
Score = 35.0 bits (79), Expect = 0.11
Identities = 33/153 (21%), Positives = 64/153 (41%), Gaps = 11/153 (7%)
Query: 26 GSDSEPGKGKGRNTGKSQTLGSKSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIPQKS 85
G + G+ K + + K +++EKR+KK+++++ ++ +K +K
Sbjct: 82 GKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERK- 140
Query: 86 SHAVCNAQHDLPLSNPVQKDSREENWQEWRQRDEQLTSEMFEADLEKALLLSK---LEYE 142
+ ++ +E +E ++R+ + E E EK K +
Sbjct: 141 ------REERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRK 194
Query: 143 EHKKEYEDAENTSTQSKVMNKKDKRKNHQGKDR 175
E KKE E E + K KK++RK + KDR
Sbjct: 195 ERKKERERKERRE-RKKERKKKEERKKERQKDR 226
Score = 34.3 bits (77), Expect = 0.18
Identities = 32/149 (21%), Positives = 67/149 (44%), Gaps = 13/149 (8%)
Query: 22 DSGSGSDSEPGKGKGRNT-GKSQTLGS-KSTTNEKKREKRRKKKEQQQSEANELRNLAFK 79
++ G + E K K + G++ G + E+KRE+R++++ +++ E K
Sbjct: 105 ENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERK 164
Query: 80 KIPQKSSHAVCNAQHDLPLSNPVQKDSREENWQEWRQRDEQLTSEMFEADLEKALLLSKL 139
K +K V + + ++ RE N +E ++ E+ E E E+
Sbjct: 165 KRERKQ---VGEKEEERKEKERKERKKRERNRKE--RKKERERKERRERKKERK------ 213
Query: 140 EYEEHKKEYEDAENTSTQSKVMNKKDKRK 168
+ EE KKE + T+ + K K+++++
Sbjct: 214 KKEERKKERQKDRQTNWREKERGKRERKE 242
Score = 33.1 bits (74), Expect = 0.40
Identities = 50/237 (21%), Positives = 94/237 (39%), Gaps = 35/237 (14%)
Query: 91 NAQHDLPLSNPVQKDSREENWQ-EWRQRDEQLTSEMFEADLEKALLLSKLEYEEHKKEYE 149
N + + + + K + WQ E R+R+ ++ + +E KKE E
Sbjct: 14 NTELQMVSCSHISKPCTQPGWQSEIREREREIETR-----------------KEGKKERE 56
Query: 150 DAENTSTQSKVMNKKDKRKNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGF 209
S + K +++KRK + K+R K+ E KK E + +
Sbjct: 57 -----SERKKERREREKRKREREKERKRERGKKEKKGE---RKKEERERKKRRREKE--- 105
Query: 210 FNRLEDDVHKILIREKRREQLTEYNGTDNCTAHEH-NQEVVLKDGRIERLKLELERKDAE 268
N+ ++ K +EK+ T G + E +E ++ + E + E ERK+ +
Sbjct: 106 -NKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERK 164
Query: 269 IQKLKNV----ITQWEAKYKEVKARNAQLLKMLQEGEMKDKAEILLQVDESQSIKNE 321
++ K V + E + KE K R + +E E K++ E + + + K E
Sbjct: 165 KRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKE 221
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 48.1 bits (113), Expect = 1e-05
Identities = 73/347 (21%), Positives = 148/347 (42%), Gaps = 43/347 (12%)
Query: 53 EKKREKRRKKKEQQQSEANELRNLAF--KKIPQKSSHAVCNAQHDLPLSNPV-------- 102
E+ RE+ ++ E+ Q +ANE L +++ Q+ S A A+ +
Sbjct: 1621 ERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAE 1680
Query: 103 -----QKDSREENWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHKKEYEDAENTSTQ 157
Q++ E+ ++ RQ E + A+ E L ++ E E +++ + E Q
Sbjct: 1681 EQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQ 1740
Query: 158 SKVMNKKDKRKNHQGK----DRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNRL 213
+ KR+ + + + V L + S+ T E S Q L + G F L
Sbjct: 1741 REAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSE-KSKQRLEAEAGRFREL 1799
Query: 214 EDDVHKI--LIRE-KRREQLTEYNGT-DNCTAHEHNQEVVLKDGRIERLKLE----LERK 265
++ ++ L E KR+ QL E + A E + G RLK E L+ K
Sbjct: 1800 AEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEK 1859
Query: 266 DAEIQKLKNV----------ITQWEAKYK-EVKARNAQLLKMLQEGEMKDKAEILLQVDE 314
+AE ++L+ + + + A++K +++ R AQL K + E++ + + V++
Sbjct: 1860 EAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRK-ASDSELERQKGL---VED 1915
Query: 315 SQSIKNELTIQVTSLHAALEQERSKVKVLQAELAKYQGGRKGKRNSE 361
+ + ++ ++ +L A+ E+ + L+ EL + + + S+
Sbjct: 1916 TLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSK 1962
Score = 40.0 bits (92), Expect = 0.003
Identities = 55/270 (20%), Positives = 113/270 (41%), Gaps = 20/270 (7%)
Query: 48 KSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHD---LPLSNPVQK 104
K E+ R + K++ Q A E + ++ +A+ + L ++ +
Sbjct: 2336 KELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRA 2395
Query: 105 DSR-EENWQEWRQRDEQLTSEMFEADL---EKALLLSKLEYEEHKKEYEDAENTSTQSKV 160
+R EE+ Q +R++ E++ ++ +L EK L+ LE + + ++ DAE
Sbjct: 2396 QARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDH-DAERLREAIAE 2454
Query: 161 MNKKDKRKNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNR---LEDDV 217
+ ++ ++ + K L ++ + ++T+ L S LS R +E +
Sbjct: 2455 LEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQS-FLSEKDSLLQRERFIEQEK 2513
Query: 218 HKI--LIREK--RREQLTEYNGTDNCTAHEHNQEVVLKDGRIERLKLELE----RKDAEI 269
K+ L +++ + +QL E + Q +V R + E E RK E+
Sbjct: 2514 AKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEEL 2573
Query: 270 QKLKNVITQWEAKYKEVKARNAQLLKMLQE 299
Q+L+ Q E E R + L++L+E
Sbjct: 2574 QQLEQQRRQQEELLAEENQRLREQLQLLEE 2603
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 48.1 bits (113), Expect = 1e-05
Identities = 73/347 (21%), Positives = 148/347 (42%), Gaps = 43/347 (12%)
Query: 53 EKKREKRRKKKEQQQSEANELRNLAF--KKIPQKSSHAVCNAQHDLPLSNPV-------- 102
E+ RE+ ++ E+ Q +ANE L +++ Q+ S A A+ +
Sbjct: 1625 ERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAE 1684
Query: 103 -----QKDSREENWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHKKEYEDAENTSTQ 157
Q++ E+ ++ RQ E + A+ E L ++ E E +++ + E Q
Sbjct: 1685 EQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQ 1744
Query: 158 SKVMNKKDKRKNHQGK----DRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNRL 213
+ KR+ + + + V L + S+ T E S Q L + G F L
Sbjct: 1745 REAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSE-KSKQRLEAEAGRFREL 1803
Query: 214 EDDVHKI--LIRE-KRREQLTEYNGT-DNCTAHEHNQEVVLKDGRIERLKLE----LERK 265
++ ++ L E KR+ QL E + A E + G RLK E L+ K
Sbjct: 1804 AEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEK 1863
Query: 266 DAEIQKLKNV----------ITQWEAKYK-EVKARNAQLLKMLQEGEMKDKAEILLQVDE 314
+AE ++L+ + + + A++K +++ R AQL K + E++ + + V++
Sbjct: 1864 EAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRK-ASDSELERQKGL---VED 1919
Query: 315 SQSIKNELTIQVTSLHAALEQERSKVKVLQAELAKYQGGRKGKRNSE 361
+ + ++ ++ +L A+ E+ + L+ EL + + + S+
Sbjct: 1920 TLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSK 1966
Score = 40.0 bits (92), Expect = 0.003
Identities = 55/270 (20%), Positives = 113/270 (41%), Gaps = 20/270 (7%)
Query: 48 KSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHD---LPLSNPVQK 104
K E+ R + K++ Q A E + ++ +A+ + L ++ +
Sbjct: 2340 KELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRA 2399
Query: 105 DSR-EENWQEWRQRDEQLTSEMFEADL---EKALLLSKLEYEEHKKEYEDAENTSTQSKV 160
+R EE+ Q +R++ E++ ++ +L EK L+ LE + + ++ DAE
Sbjct: 2400 QARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDH-DAERLREAIAE 2458
Query: 161 MNKKDKRKNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNR---LEDDV 217
+ ++ ++ + K L ++ + ++T+ L S LS R +E +
Sbjct: 2459 LEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQS-FLSEKDSLLQRERFIEQEK 2517
Query: 218 HKI--LIREK--RREQLTEYNGTDNCTAHEHNQEVVLKDGRIERLKLELE----RKDAEI 269
K+ L +++ + +QL E + Q +V R + E E RK E+
Sbjct: 2518 AKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEEL 2577
Query: 270 QKLKNVITQWEAKYKEVKARNAQLLKMLQE 299
Q+L+ Q E E R + L++L+E
Sbjct: 2578 QQLEQQRRQQEELLAEENQRLREQLQLLEE 2607
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 48.1 bits (113), Expect = 1e-05
Identities = 73/347 (21%), Positives = 148/347 (42%), Gaps = 43/347 (12%)
Query: 53 EKKREKRRKKKEQQQSEANELRNLAF--KKIPQKSSHAVCNAQHDLPLSNPV-------- 102
E+ RE+ ++ E+ Q +ANE L +++ Q+ S A A+ +
Sbjct: 1621 ERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAE 1680
Query: 103 -----QKDSREENWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHKKEYEDAENTSTQ 157
Q++ E+ ++ RQ E + A+ E L ++ E E +++ + E Q
Sbjct: 1681 EQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQ 1740
Query: 158 SKVMNKKDKRKNHQGK----DRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNRL 213
+ KR+ + + + V L + S+ T E S Q L + G F L
Sbjct: 1741 REAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSE-KSKQRLEAEAGRFREL 1799
Query: 214 EDDVHKI--LIRE-KRREQLTEYNGT-DNCTAHEHNQEVVLKDGRIERLKLE----LERK 265
++ ++ L E KR+ QL E + A E + G RLK E L+ K
Sbjct: 1800 AEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEK 1859
Query: 266 DAEIQKLKNV----------ITQWEAKYK-EVKARNAQLLKMLQEGEMKDKAEILLQVDE 314
+AE ++L+ + + + A++K +++ R AQL K + E++ + + V++
Sbjct: 1860 EAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRK-ASDSELERQKGL---VED 1915
Query: 315 SQSIKNELTIQVTSLHAALEQERSKVKVLQAELAKYQGGRKGKRNSE 361
+ + ++ ++ +L A+ E+ + L+ EL + + + S+
Sbjct: 1916 TLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSK 1962
Score = 40.0 bits (92), Expect = 0.003
Identities = 55/270 (20%), Positives = 113/270 (41%), Gaps = 20/270 (7%)
Query: 48 KSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHD---LPLSNPVQK 104
K E+ R + K++ Q A E + ++ +A+ + L ++ +
Sbjct: 2336 KELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRA 2395
Query: 105 DSR-EENWQEWRQRDEQLTSEMFEADL---EKALLLSKLEYEEHKKEYEDAENTSTQSKV 160
+R EE+ Q +R++ E++ ++ +L EK L+ LE + + ++ DAE
Sbjct: 2396 QARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDH-DAERLREAIAE 2454
Query: 161 MNKKDKRKNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNR---LEDDV 217
+ ++ ++ + K L ++ + ++T+ L S LS R +E +
Sbjct: 2455 LEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQS-FLSEKDSLLQRERFIEQEK 2513
Query: 218 HKI--LIREK--RREQLTEYNGTDNCTAHEHNQEVVLKDGRIERLKLELE----RKDAEI 269
K+ L +++ + +QL E + Q +V R + E E RK E+
Sbjct: 2514 AKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEEL 2573
Query: 270 QKLKNVITQWEAKYKEVKARNAQLLKMLQE 299
Q+L+ Q E E R + L++L+E
Sbjct: 2574 QQLEQQRRQQEELLAEENQRLREQLQLLEE 2603
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 48.1 bits (113), Expect = 1e-05
Identities = 73/347 (21%), Positives = 148/347 (42%), Gaps = 43/347 (12%)
Query: 53 EKKREKRRKKKEQQQSEANELRNLAF--KKIPQKSSHAVCNAQHDLPLSNPV-------- 102
E+ RE+ ++ E+ Q +ANE L +++ Q+ S A A+ +
Sbjct: 1589 ERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAE 1648
Query: 103 -----QKDSREENWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHKKEYEDAENTSTQ 157
Q++ E+ ++ RQ E + A+ E L ++ E E +++ + E Q
Sbjct: 1649 EQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQ 1708
Query: 158 SKVMNKKDKRKNHQGK----DRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNRL 213
+ KR+ + + + V L + S+ T E S Q L + G F L
Sbjct: 1709 REAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSE-KSKQRLEAEAGRFREL 1767
Query: 214 EDDVHKI--LIRE-KRREQLTEYNGT-DNCTAHEHNQEVVLKDGRIERLKLE----LERK 265
++ ++ L E KR+ QL E + A E + G RLK E L+ K
Sbjct: 1768 AEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEK 1827
Query: 266 DAEIQKLKNV----------ITQWEAKYK-EVKARNAQLLKMLQEGEMKDKAEILLQVDE 314
+AE ++L+ + + + A++K +++ R AQL K + E++ + + V++
Sbjct: 1828 EAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRK-ASDSELERQKGL---VED 1883
Query: 315 SQSIKNELTIQVTSLHAALEQERSKVKVLQAELAKYQGGRKGKRNSE 361
+ + ++ ++ +L A+ E+ + L+ EL + + + S+
Sbjct: 1884 TLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSK 1930
Score = 40.0 bits (92), Expect = 0.003
Identities = 55/270 (20%), Positives = 113/270 (41%), Gaps = 20/270 (7%)
Query: 48 KSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHD---LPLSNPVQK 104
K E+ R + K++ Q A E + ++ +A+ + L ++ +
Sbjct: 2304 KELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRA 2363
Query: 105 DSR-EENWQEWRQRDEQLTSEMFEADL---EKALLLSKLEYEEHKKEYEDAENTSTQSKV 160
+R EE+ Q +R++ E++ ++ +L EK L+ LE + + ++ DAE
Sbjct: 2364 QARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDH-DAERLREAIAE 2422
Query: 161 MNKKDKRKNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNR---LEDDV 217
+ ++ ++ + K L ++ + ++T+ L S LS R +E +
Sbjct: 2423 LEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQS-FLSEKDSLLQRERFIEQEK 2481
Query: 218 HKI--LIREK--RREQLTEYNGTDNCTAHEHNQEVVLKDGRIERLKLELE----RKDAEI 269
K+ L +++ + +QL E + Q +V R + E E RK E+
Sbjct: 2482 AKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEEL 2541
Query: 270 QKLKNVITQWEAKYKEVKARNAQLLKMLQE 299
Q+L+ Q E E R + L++L+E
Sbjct: 2542 QQLEQQRRQQEELLAEENQRLREQLQLLEE 2571
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 48.1 bits (113), Expect = 1e-05
Identities = 73/347 (21%), Positives = 148/347 (42%), Gaps = 43/347 (12%)
Query: 53 EKKREKRRKKKEQQQSEANELRNLAF--KKIPQKSSHAVCNAQHDLPLSNPV-------- 102
E+ RE+ ++ E+ Q +ANE L +++ Q+ S A A+ +
Sbjct: 1758 ERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAE 1817
Query: 103 -----QKDSREENWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHKKEYEDAENTSTQ 157
Q++ E+ ++ RQ E + A+ E L ++ E E +++ + E Q
Sbjct: 1818 EQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQ 1877
Query: 158 SKVMNKKDKRKNHQGK----DRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNRL 213
+ KR+ + + + V L + S+ T E S Q L + G F L
Sbjct: 1878 REAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSE-KSKQRLEAEAGRFREL 1936
Query: 214 EDDVHKI--LIRE-KRREQLTEYNGT-DNCTAHEHNQEVVLKDGRIERLKLE----LERK 265
++ ++ L E KR+ QL E + A E + G RLK E L+ K
Sbjct: 1937 AEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEK 1996
Query: 266 DAEIQKLKNV----------ITQWEAKYK-EVKARNAQLLKMLQEGEMKDKAEILLQVDE 314
+AE ++L+ + + + A++K +++ R AQL K + E++ + + V++
Sbjct: 1997 EAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRK-ASDSELERQKGL---VED 2052
Query: 315 SQSIKNELTIQVTSLHAALEQERSKVKVLQAELAKYQGGRKGKRNSE 361
+ + ++ ++ +L A+ E+ + L+ EL + + + S+
Sbjct: 2053 TLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSK 2099
Score = 40.0 bits (92), Expect = 0.003
Identities = 55/270 (20%), Positives = 113/270 (41%), Gaps = 20/270 (7%)
Query: 48 KSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHD---LPLSNPVQK 104
K E+ R + K++ Q A E + ++ +A+ + L ++ +
Sbjct: 2473 KELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRA 2532
Query: 105 DSR-EENWQEWRQRDEQLTSEMFEADL---EKALLLSKLEYEEHKKEYEDAENTSTQSKV 160
+R EE+ Q +R++ E++ ++ +L EK L+ LE + + ++ DAE
Sbjct: 2533 QARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDH-DAERLREAIAE 2591
Query: 161 MNKKDKRKNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNR---LEDDV 217
+ ++ ++ + K L ++ + ++T+ L S LS R +E +
Sbjct: 2592 LEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQS-FLSEKDSLLQRERFIEQEK 2650
Query: 218 HKI--LIREK--RREQLTEYNGTDNCTAHEHNQEVVLKDGRIERLKLELE----RKDAEI 269
K+ L +++ + +QL E + Q +V R + E E RK E+
Sbjct: 2651 AKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEEL 2710
Query: 270 QKLKNVITQWEAKYKEVKARNAQLLKMLQE 299
Q+L+ Q E E R + L++L+E
Sbjct: 2711 QQLEQQRRQQEELLAEENQRLREQLQLLEE 2740
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 48.1 bits (113), Expect = 1e-05
Identities = 73/347 (21%), Positives = 148/347 (42%), Gaps = 43/347 (12%)
Query: 53 EKKREKRRKKKEQQQSEANELRNLAF--KKIPQKSSHAVCNAQHDLPLSNPV-------- 102
E+ RE+ ++ E+ Q +ANE L +++ Q+ S A A+ +
Sbjct: 1599 ERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAE 1658
Query: 103 -----QKDSREENWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHKKEYEDAENTSTQ 157
Q++ E+ ++ RQ E + A+ E L ++ E E +++ + E Q
Sbjct: 1659 EQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQ 1718
Query: 158 SKVMNKKDKRKNHQGK----DRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNRL 213
+ KR+ + + + V L + S+ T E S Q L + G F L
Sbjct: 1719 REAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSE-KSKQRLEAEAGRFREL 1777
Query: 214 EDDVHKI--LIRE-KRREQLTEYNGT-DNCTAHEHNQEVVLKDGRIERLKLE----LERK 265
++ ++ L E KR+ QL E + A E + G RLK E L+ K
Sbjct: 1778 AEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEK 1837
Query: 266 DAEIQKLKNV----------ITQWEAKYK-EVKARNAQLLKMLQEGEMKDKAEILLQVDE 314
+AE ++L+ + + + A++K +++ R AQL K + E++ + + V++
Sbjct: 1838 EAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRK-ASDSELERQKGL---VED 1893
Query: 315 SQSIKNELTIQVTSLHAALEQERSKVKVLQAELAKYQGGRKGKRNSE 361
+ + ++ ++ +L A+ E+ + L+ EL + + + S+
Sbjct: 1894 TLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSK 1940
Score = 40.0 bits (92), Expect = 0.003
Identities = 55/270 (20%), Positives = 113/270 (41%), Gaps = 20/270 (7%)
Query: 48 KSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHD---LPLSNPVQK 104
K E+ R + K++ Q A E + ++ +A+ + L ++ +
Sbjct: 2314 KELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRA 2373
Query: 105 DSR-EENWQEWRQRDEQLTSEMFEADL---EKALLLSKLEYEEHKKEYEDAENTSTQSKV 160
+R EE+ Q +R++ E++ ++ +L EK L+ LE + + ++ DAE
Sbjct: 2374 QARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDH-DAERLREAIAE 2432
Query: 161 MNKKDKRKNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNR---LEDDV 217
+ ++ ++ + K L ++ + ++T+ L S LS R +E +
Sbjct: 2433 LEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQS-FLSEKDSLLQRERFIEQEK 2491
Query: 218 HKI--LIREK--RREQLTEYNGTDNCTAHEHNQEVVLKDGRIERLKLELE----RKDAEI 269
K+ L +++ + +QL E + Q +V R + E E RK E+
Sbjct: 2492 AKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEEL 2551
Query: 270 QKLKNVITQWEAKYKEVKARNAQLLKMLQE 299
Q+L+ Q E E R + L++L+E
Sbjct: 2552 QQLEQQRRQQEELLAEENQRLREQLQLLEE 2581
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 48.1 bits (113), Expect = 1e-05
Identities = 73/347 (21%), Positives = 148/347 (42%), Gaps = 43/347 (12%)
Query: 53 EKKREKRRKKKEQQQSEANELRNLAF--KKIPQKSSHAVCNAQHDLPLSNPV-------- 102
E+ RE+ ++ E+ Q +ANE L +++ Q+ S A A+ +
Sbjct: 1607 ERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAE 1666
Query: 103 -----QKDSREENWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHKKEYEDAENTSTQ 157
Q++ E+ ++ RQ E + A+ E L ++ E E +++ + E Q
Sbjct: 1667 EQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQ 1726
Query: 158 SKVMNKKDKRKNHQGK----DRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNRL 213
+ KR+ + + + V L + S+ T E S Q L + G F L
Sbjct: 1727 REAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSE-KSKQRLEAEAGRFREL 1785
Query: 214 EDDVHKI--LIRE-KRREQLTEYNGT-DNCTAHEHNQEVVLKDGRIERLKLE----LERK 265
++ ++ L E KR+ QL E + A E + G RLK E L+ K
Sbjct: 1786 AEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEK 1845
Query: 266 DAEIQKLKNV----------ITQWEAKYK-EVKARNAQLLKMLQEGEMKDKAEILLQVDE 314
+AE ++L+ + + + A++K +++ R AQL K + E++ + + V++
Sbjct: 1846 EAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRK-ASDSELERQKGL---VED 1901
Query: 315 SQSIKNELTIQVTSLHAALEQERSKVKVLQAELAKYQGGRKGKRNSE 361
+ + ++ ++ +L A+ E+ + L+ EL + + + S+
Sbjct: 1902 TLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSK 1948
Score = 40.0 bits (92), Expect = 0.003
Identities = 55/270 (20%), Positives = 113/270 (41%), Gaps = 20/270 (7%)
Query: 48 KSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHD---LPLSNPVQK 104
K E+ R + K++ Q A E + ++ +A+ + L ++ +
Sbjct: 2322 KELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRA 2381
Query: 105 DSR-EENWQEWRQRDEQLTSEMFEADL---EKALLLSKLEYEEHKKEYEDAENTSTQSKV 160
+R EE+ Q +R++ E++ ++ +L EK L+ LE + + ++ DAE
Sbjct: 2382 QARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDH-DAERLREAIAE 2440
Query: 161 MNKKDKRKNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNR---LEDDV 217
+ ++ ++ + K L ++ + ++T+ L S LS R +E +
Sbjct: 2441 LEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQS-FLSEKDSLLQRERFIEQEK 2499
Query: 218 HKI--LIREK--RREQLTEYNGTDNCTAHEHNQEVVLKDGRIERLKLELE----RKDAEI 269
K+ L +++ + +QL E + Q +V R + E E RK E+
Sbjct: 2500 AKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEEL 2559
Query: 270 QKLKNVITQWEAKYKEVKARNAQLLKMLQE 299
Q+L+ Q E E R + L++L+E
Sbjct: 2560 QQLEQQRRQQEELLAEENQRLREQLQLLEE 2589
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 48.1 bits (113), Expect = 1e-05
Identities = 73/347 (21%), Positives = 148/347 (42%), Gaps = 43/347 (12%)
Query: 53 EKKREKRRKKKEQQQSEANELRNLAF--KKIPQKSSHAVCNAQHDLPLSNPV-------- 102
E+ RE+ ++ E+ Q +ANE L +++ Q+ S A A+ +
Sbjct: 1648 ERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAE 1707
Query: 103 -----QKDSREENWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHKKEYEDAENTSTQ 157
Q++ E+ ++ RQ E + A+ E L ++ E E +++ + E Q
Sbjct: 1708 EQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQ 1767
Query: 158 SKVMNKKDKRKNHQGK----DRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNRL 213
+ KR+ + + + V L + S+ T E S Q L + G F L
Sbjct: 1768 REAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSE-KSKQRLEAEAGRFREL 1826
Query: 214 EDDVHKI--LIRE-KRREQLTEYNGT-DNCTAHEHNQEVVLKDGRIERLKLE----LERK 265
++ ++ L E KR+ QL E + A E + G RLK E L+ K
Sbjct: 1827 AEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEK 1886
Query: 266 DAEIQKLKNV----------ITQWEAKYK-EVKARNAQLLKMLQEGEMKDKAEILLQVDE 314
+AE ++L+ + + + A++K +++ R AQL K + E++ + + V++
Sbjct: 1887 EAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRK-ASDSELERQKGL---VED 1942
Query: 315 SQSIKNELTIQVTSLHAALEQERSKVKVLQAELAKYQGGRKGKRNSE 361
+ + ++ ++ +L A+ E+ + L+ EL + + + S+
Sbjct: 1943 TLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSK 1989
Score = 40.0 bits (92), Expect = 0.003
Identities = 55/270 (20%), Positives = 113/270 (41%), Gaps = 20/270 (7%)
Query: 48 KSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHD---LPLSNPVQK 104
K E+ R + K++ Q A E + ++ +A+ + L ++ +
Sbjct: 2363 KELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRA 2422
Query: 105 DSR-EENWQEWRQRDEQLTSEMFEADL---EKALLLSKLEYEEHKKEYEDAENTSTQSKV 160
+R EE+ Q +R++ E++ ++ +L EK L+ LE + + ++ DAE
Sbjct: 2423 QARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDH-DAERLREAIAE 2481
Query: 161 MNKKDKRKNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNR---LEDDV 217
+ ++ ++ + K L ++ + ++T+ L S LS R +E +
Sbjct: 2482 LEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQS-FLSEKDSLLQRERFIEQEK 2540
Query: 218 HKI--LIREK--RREQLTEYNGTDNCTAHEHNQEVVLKDGRIERLKLELE----RKDAEI 269
K+ L +++ + +QL E + Q +V R + E E RK E+
Sbjct: 2541 AKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEEL 2600
Query: 270 QKLKNVITQWEAKYKEVKARNAQLLKMLQE 299
Q+L+ Q E E R + L++L+E
Sbjct: 2601 QQLEQQRRQQEELLAEENQRLREQLQLLEE 2630
>gi|15149463 caldesmon 1 isoform 4 [Homo sapiens]
Length = 558
Score = 48.1 bits (113), Expect = 1e-05
Identities = 66/350 (18%), Positives = 138/350 (39%), Gaps = 59/350 (16%)
Query: 25 SGSDSEPGKGKGRNTGKSQTLGSKSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIPQK 84
+ +S P + T +Q G ++ +R ++++++ EA E + ++
Sbjct: 63 NAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQ--------KE 114
Query: 85 SSHAVCNAQHDLPLSNPVQKDSREENWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEH 144
+ +A LP S +Q D+ E E +++E+ S ++E+ ++K
Sbjct: 115 FDPTITDASLSLP-SRRMQNDTAEN---ETTEKEEKSESRQERYEIEETETVTK---SYQ 167
Query: 145 KKEYEDAENTSTQSKVMNKKDKRKNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLS 204
K ++ DAE K+DK K + +++P S+ + E+ K T+ + + L
Sbjct: 168 KNDWRDAEENK-------KEDKEKEEEEEEKPKRGSIGENQGEE---KGTKVQAKREKLQ 217
Query: 205 HDGGFFNRLE-------------DDVHKILIREKRREQLTEYNGTDNCTAHEHNQEVVLK 251
D F + E ++V + R+K ++ NG +H + +
Sbjct: 218 EDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSR 277
Query: 252 DG--------------------RIERLKLEL-ERKDAEIQKLKNVITQWEAKYKEVKARN 290
G R+E L+ E + E +KLK + + +E+K +
Sbjct: 278 PGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKR 337
Query: 291 AQLLKMLQEGEMKDKAEILLQVDESQSIKNELTIQVTSLHAALEQERSKV 340
+ K+L+E E + K E + + K L ++ A ++R K+
Sbjct: 338 EERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKM 387
>gi|15149467 caldesmon 1 isoform 3 [Homo sapiens]
Length = 564
Score = 48.1 bits (113), Expect = 1e-05
Identities = 66/350 (18%), Positives = 138/350 (39%), Gaps = 59/350 (16%)
Query: 25 SGSDSEPGKGKGRNTGKSQTLGSKSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIPQK 84
+ +S P + T +Q G ++ +R ++++++ EA E + ++
Sbjct: 69 NAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQ--------KE 120
Query: 85 SSHAVCNAQHDLPLSNPVQKDSREENWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEH 144
+ +A LP S +Q D+ E E +++E+ S ++E+ ++K
Sbjct: 121 FDPTITDASLSLP-SRRMQNDTAEN---ETTEKEEKSESRQERYEIEETETVTK---SYQ 173
Query: 145 KKEYEDAENTSTQSKVMNKKDKRKNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLS 204
K ++ DAE K+DK K + +++P S+ + E+ K T+ + + L
Sbjct: 174 KNDWRDAEENK-------KEDKEKEEEEEEKPKRGSIGENQGEE---KGTKVQAKREKLQ 223
Query: 205 HDGGFFNRLE-------------DDVHKILIREKRREQLTEYNGTDNCTAHEHNQEVVLK 251
D F + E ++V + R+K ++ NG +H + +
Sbjct: 224 EDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSR 283
Query: 252 DG--------------------RIERLKLEL-ERKDAEIQKLKNVITQWEAKYKEVKARN 290
G R+E L+ E + E +KLK + + +E+K +
Sbjct: 284 PGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKR 343
Query: 291 AQLLKMLQEGEMKDKAEILLQVDESQSIKNELTIQVTSLHAALEQERSKV 340
+ K+L+E E + K E + + K L ++ A ++R K+
Sbjct: 344 EERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKM 393
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.123 0.328
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,081,293
Number of Sequences: 37866
Number of extensions: 599530
Number of successful extensions: 7167
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 135
Number of HSP's successfully gapped in prelim test: 784
Number of HSP's that attempted gapping in prelim test: 4978
Number of HSP's gapped (non-prelim): 2373
length of query: 366
length of database: 18,247,518
effective HSP length: 104
effective length of query: 262
effective length of database: 14,309,454
effective search space: 3749076948
effective search space used: 3749076948
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.