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Search of human proteins with 20070193
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20070193 nuclear receptor subfamily 5, group A, member 1
[Homo sapiens]
(461 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20070193 nuclear receptor subfamily 5, group A, member 1 [Hom... 957 0.0
gi|45545405 nuclear receptor subfamily 5, group A, member 2 isof... 560 e-159
gi|4504343 nuclear receptor subfamily 5, group A, member 2 isofo... 560 e-159
gi|53729325 nuclear receptor subfamily 6, group A, member 1 isof... 151 1e-36
gi|53729327 nuclear receptor subfamily 6, group A, member 1 isof... 151 1e-36
gi|238550159 estrogen-related receptor beta [Homo sapiens] 119 6e-27
gi|18860920 estrogen-related receptor alpha [Homo sapiens] 118 1e-26
gi|45545429 estrogen-related receptor gamma isoform 2 [Homo sapi... 118 1e-26
gi|45545427 estrogen-related receptor gamma isoform 2 [Homo sapi... 118 1e-26
gi|45545433 estrogen-related receptor gamma isoform 1 [Homo sapi... 118 1e-26
gi|197209821 estrogen-related receptor gamma isoform 2 [Homo sap... 118 1e-26
gi|27894344 nuclear receptor subfamily 4, group A, member 1 [Hom... 113 4e-25
gi|21361342 nuclear receptor subfamily 4, group A, member 1 [Hom... 113 4e-25
gi|4506755 retinoid X receptor, alpha [Homo sapiens] 112 5e-25
gi|13430848 nuclear receptor subfamily 1, group D, member 1 [Hom... 112 5e-25
gi|5453822 nuclear receptor subfamily 4, group A, member 2 [Homo... 112 7e-25
gi|27894361 nuclear receptor subfamily 4, group A, member 3 isof... 112 7e-25
gi|27894359 nuclear receptor subfamily 4, group A, member 3 isof... 112 7e-25
gi|27894357 nuclear receptor subfamily 4, group A, member 3 isof... 112 7e-25
gi|27894355 nuclear receptor subfamily 4, group A, member 3 isof... 112 7e-25
gi|11415052 retinoid X receptor, beta [Homo sapiens] 111 2e-24
gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens] 109 5e-24
gi|19743907 RAR-related orphan receptor B [Homo sapiens] 109 6e-24
gi|19743905 RAR-related orphan receptor A isoform d [Homo sapiens] 108 1e-23
gi|4506577 RAR-related orphan receptor A isoform c [Homo sapiens] 108 1e-23
gi|19743901 RAR-related orphan receptor A isoform b [Homo sapiens] 108 1e-23
gi|19743903 RAR-related orphan receptor A isoform a [Homo sapiens] 108 1e-23
gi|48255918 RAR-related orphan receptor C isoform b [Homo sapiens] 106 5e-23
gi|19743909 RAR-related orphan receptor C isoform a [Homo sapiens] 106 5e-23
gi|40806160 thyroid hormone receptor, alpha isoform 1 [Homo sapi... 105 7e-23
>gi|20070193 nuclear receptor subfamily 5, group A, member 1 [Homo
sapiens]
Length = 461
Score = 957 bits (2474), Expect = 0.0
Identities = 461/461 (100%), Positives = 461/461 (100%)
Query: 1 MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKT 60
MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKT
Sbjct: 1 MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKT 60
Query: 61 QRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKL 120
QRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKL
Sbjct: 61 QRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKL 120
Query: 121 ETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPL 180
ETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPL
Sbjct: 121 ETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPL 180
Query: 181 AGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQV 240
AGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQV
Sbjct: 181 AGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQV 240
Query: 241 RARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQN 300
RARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQN
Sbjct: 241 RARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQN 300
Query: 301 CWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLA 360
CWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLA
Sbjct: 301 CWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLA 360
Query: 361 LQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLL 420
LQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLL
Sbjct: 361 LQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLL 420
Query: 421 LCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT 461
LCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
Sbjct: 421 LCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT 461
>gi|45545405 nuclear receptor subfamily 5, group A, member 2 isoform
1 [Homo sapiens]
Length = 541
Score = 560 bits (1442), Expect = e-159
Identities = 288/470 (61%), Positives = 356/470 (75%), Gaps = 13/470 (2%)
Query: 1 MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKT 60
++YSYDEDL+ELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNK YTC E+Q+C+IDKT
Sbjct: 74 VNYSYDEDLEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKT 133
Query: 61 QRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKL 120
QRKRCP+CRFQKCL+VGM+LEAVRADRMRGGRNKFGPMYKRDRALKQQKKA IRANG KL
Sbjct: 134 QRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLKL 193
Query: 121 ETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGD-----FGAPALPMAVPG 175
E + + P ++H KGL A P D F + M +P
Sbjct: 194 EAMSQV-IQAMPSDLTISSAIQNIHSAS-KGLPLNHAALPPTDYDRSPFVTSPISMTMP- 250
Query: 176 AHGPLAGY-LYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPF--SGGPNVPELILQLLQ 232
HG L GY Y FP RAIKSEYP+PY S P+ + Y Y + + S ++P LIL+LL+
Sbjct: 251 PHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMGYSYMDSYQTSSPASIPHLILELLK 310
Query: 233 LEPDEDQVRARILGCLQEP--TKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELE 290
EPDE QV+A+I+ LQ+ +S+ ++ + FGL+C+MADQT SIV+WAR + F+EL+
Sbjct: 311 CEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELK 370
Query: 291 VADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLR 350
V DQM LLQNCWSELL+ DHIYRQV HGKEGSI LVTGQ+V+ + +A+QAG+ L++L+
Sbjct: 371 VDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSH 430
Query: 351 AQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYP 410
AQELV +L +LQ D++EFVCLKF++LFSLD+K L N LV+ QE+ NAALLDYT+C+YP
Sbjct: 431 AQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYP 490
Query: 411 HCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQ 460
+KF QLLL L E+RA+SMQA+EYLY+KHL ++P NNLLIEML AK+
Sbjct: 491 QQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDVPYNNLLIEMLHAKR 540
>gi|4504343 nuclear receptor subfamily 5, group A, member 2 isoform
2 [Homo sapiens]
Length = 495
Score = 560 bits (1442), Expect = e-159
Identities = 288/470 (61%), Positives = 356/470 (75%), Gaps = 13/470 (2%)
Query: 1 MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKT 60
++YSYDEDL+ELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNK YTC E+Q+C+IDKT
Sbjct: 28 VNYSYDEDLEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKT 87
Query: 61 QRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKL 120
QRKRCP+CRFQKCL+VGM+LEAVRADRMRGGRNKFGPMYKRDRALKQQKKA IRANG KL
Sbjct: 88 QRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLKL 147
Query: 121 ETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGD-----FGAPALPMAVPG 175
E + + P ++H KGL A P D F + M +P
Sbjct: 148 EAMSQV-IQAMPSDLTISSAIQNIHSAS-KGLPLNHAALPPTDYDRSPFVTSPISMTMP- 204
Query: 176 AHGPLAGY-LYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPF--SGGPNVPELILQLLQ 232
HG L GY Y FP RAIKSEYP+PY S P+ + Y Y + + S ++P LIL+LL+
Sbjct: 205 PHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMGYSYMDSYQTSSPASIPHLILELLK 264
Query: 233 LEPDEDQVRARILGCLQEP--TKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELE 290
EPDE QV+A+I+ LQ+ +S+ ++ + FGL+C+MADQT SIV+WAR + F+EL+
Sbjct: 265 CEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELK 324
Query: 291 VADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLR 350
V DQM LLQNCWSELL+ DHIYRQV HGKEGSI LVTGQ+V+ + +A+QAG+ L++L+
Sbjct: 325 VDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSH 384
Query: 351 AQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYP 410
AQELV +L +LQ D++EFVCLKF++LFSLD+K L N LV+ QE+ NAALLDYT+C+YP
Sbjct: 385 AQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYP 444
Query: 411 HCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQ 460
+KF QLLL L E+RA+SMQA+EYLY+KHL ++P NNLLIEML AK+
Sbjct: 445 QQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDVPYNNLLIEMLHAKR 494
>gi|53729325 nuclear receptor subfamily 6, group A, member 1 isoform
1 [Homo sapiens]
Length = 480
Score = 151 bits (382), Expect = 1e-36
Identities = 118/443 (26%), Positives = 200/443 (45%), Gaps = 58/443 (13%)
Query: 4 SYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRK 63
S D C +CGD+ +G HYG+++CE CKGFFKR++ N + Y C+ ++C + + QR
Sbjct: 51 SDDRAEQRTCLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRN 110
Query: 64 RCPFCRFQKCLTVGMRLEAVRADRMRGGRNK-FGPMYKRDRALKQ-------QKKAQIRA 115
RC +CR KCL +GM +A+R D M GGRNK GP+ + +++ +++A +
Sbjct: 111 RCQYCRLLKCLQMGMNRKAIREDGMPGGRNKSIGPVQISEEEIERIMSGQEFEEEANHWS 170
Query: 116 N-GFKLETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVP 174
N G + P P+P L S E G A F + M+VP
Sbjct: 171 NHGDSDHSSPGNRASESNQPSPGSTLSSS-RSVELNGFMA---------FREQYMGMSVP 220
Query: 175 GAHGPLAGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLE 234
H +L+ ++ G + P LP + S P LI QLL E
Sbjct: 221 -PHYQYIPHLF-SYSGHS--------------PLLP---QQARSLDPQSYSLIHQLLSAE 261
Query: 235 PDEDQVRARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQ 294
E ++ T Q F LLCR+AD+ + W ++ F EL + D
Sbjct: 262 DLEPLGTPMLIEDGYAVT-----QAELFALLCRLADELLFRQIAWIKKLPFFCELSIKDY 316
Query: 295 MTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQEL 354
LL + W EL++ + + K+ + G+ ++T + + LH E+
Sbjct: 317 TCLLSSTWQELILLSSL---TVYSKQ-----IFGELADVTAKYSPSDEELHRFSDEGMEV 368
Query: 355 VLQLL-------ALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLC 407
+ +L+ L++ +E+ C+K I + D++ L + ++ ++ D+T
Sbjct: 369 IERLIYLYHKFHQLKVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKRYWYICQDFTEY 428
Query: 408 HYPHCGDKFQQLLLCLVEVRALS 430
Y H ++F L++CL E+R ++
Sbjct: 429 KYTHQPNRFPDLMMCLPEIRYIA 451
>gi|53729327 nuclear receptor subfamily 6, group A, member 1 isoform
2 [Homo sapiens]
Length = 475
Score = 151 bits (381), Expect = 1e-36
Identities = 111/436 (25%), Positives = 191/436 (43%), Gaps = 63/436 (14%)
Query: 13 CPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQK 72
C +CGD+ +G HYG+++CE CKGFFKR++ N + Y C+ ++C + + QR RC +CR K
Sbjct: 56 CLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLK 115
Query: 73 CLTVGMRLEAVRADRMRGGRNK-FGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPP 131
CL +GM +A+R D M GGRNK GP+ + +++ Q F+ E
Sbjct: 116 CLQMGMNRKAIREDGMPGGRNKSIGPVQISEEEIERIMSGQ----EFEEEAN-------- 163
Query: 132 PPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPLAGYLYPAFPGR 191
S HG P + P+ + L G++
Sbjct: 164 ---------HWSNHGDSDH----SSPGNRASESNQPSPGSTLSSRSVELNGFM------- 203
Query: 192 AIKSEYPEPYASPPQPGLPYGY-PEPFSGGPNVPELILQLLQLEPDEDQVRARILGCLQE 250
A + +Y + PP Y Y P FS + P L Q L+P + ++L
Sbjct: 204 AFREQY-MGMSVPPH----YQYIPHLFSYSGHSPLLPQQARSLDPQSYSLIHQLLSAEDL 258
Query: 251 PTKSRP---------DQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNC 301
P Q F LLCR+AD+ + W ++ F EL + D LL +
Sbjct: 259 EPLGTPMLIEDGYAVTQAELFALLCRLADELLFRQIAWIKKLPFFCELSIKDYTCLLSST 318
Query: 302 WSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLL-- 359
W EL++ + + K+ + G+ ++T + + LH E++ +L+
Sbjct: 319 WQELILLSSL---TVYSKQ-----IFGELADVTAKYSPSDEELHRFSDEGMEVIERLIYL 370
Query: 360 -----ALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGD 414
L++ +E+ C+K I + D++ L + ++ ++ D+T Y H +
Sbjct: 371 YHKFHQLKVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKRYWYICQDFTEYKYTHQPN 430
Query: 415 KFQQLLLCLVEVRALS 430
+F L++CL E+R ++
Sbjct: 431 RFPDLMMCLPEIRYIA 446
>gi|238550159 estrogen-related receptor beta [Homo sapiens]
Length = 508
Score = 119 bits (298), Expect = 6e-27
Identities = 70/157 (44%), Positives = 83/157 (52%), Gaps = 21/157 (13%)
Query: 12 LCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQ 71
LC VCGD SGYHYG+ +CE+CK FFKRT+Q N Y+C + C+I K +RK C CRF
Sbjct: 102 LCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFM 161
Query: 72 KCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVP-P 130
KCL VGM E VR DR+RGGR K YKR E+ P + +
Sbjct: 162 KCLKVGMLKEGVRLDRVRGGRQK----YKR---------------RLDSESSPYLSLQIS 202
Query: 131 PPPPAPDYVLPPSLHGPEPKGLAAGPPAG-PLGDFGA 166
PP P + L EP L A PP G P GD A
Sbjct: 203 PPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIKA 239
Score = 90.9 bits (224), Expect = 2e-18
Identities = 68/239 (28%), Positives = 118/239 (49%), Gaps = 15/239 (6%)
Query: 231 LQLEPDEDQVRARILGCL--QEPTK----SRPDQPA----AFGLLCRMADQTFISIVDWA 280
LQ+ P + +I+ L EP K P P A LC +AD+ + I+ WA
Sbjct: 199 LQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIKALTTLCDLADRELVVIIGWA 258
Query: 281 RRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQA 340
+ F L + DQM+LLQ+ W E+L+ +YR + + + LV ++ + ++
Sbjct: 259 KHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDK----LVYAEDYIMDEEHSRL 314
Query: 341 GSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAA 400
LL L +LV + L+++++EFV LK + L + D ++ + V+ Q+ + A
Sbjct: 315 AGLL-ELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDLEAVQKLQDLLHEA 373
Query: 401 LLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAK 459
L DY L + +LLL L +R + +A ++ Y L ++P + L +EML+AK
Sbjct: 374 LQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVPMHKLFLEMLEAK 432
>gi|18860920 estrogen-related receptor alpha [Homo sapiens]
Length = 423
Score = 118 bits (296), Expect = 1e-26
Identities = 70/159 (44%), Positives = 85/159 (53%), Gaps = 12/159 (7%)
Query: 12 LCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQ 71
LC VCGD SGYHYG+ +CE+CK FFKRT+Q + Y+C S C+I K +RK C CRF
Sbjct: 78 LCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFT 137
Query: 72 KCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKLETGP-PMGVPP 130
KCL VGM E VR DR+RGGR K+ K++ + GP + P
Sbjct: 138 KCLRVGMLKEGVRLDRVRGGRQKY----------KRRPEVDPLPFPGPFPAGPLAVAGGP 187
Query: 131 PPPPAPDYVLPPSLHGPEPKGLAAGP-PAGPLGDFGAPA 168
AP L L EP+ L A P PAGP G A A
Sbjct: 188 RKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVA 226
Score = 81.3 bits (199), Expect = 2e-15
Identities = 72/265 (27%), Positives = 120/265 (45%), Gaps = 29/265 (10%)
Query: 210 PYGYPEPFSGGP------------NVPELILQLLQLEPDEDQVRARILGCLQEPTKSRPD 257
P +P PF GP V L+ LL +EP++ L + +P
Sbjct: 169 PLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEK-------LYAMPDPAGPDGH 221
Query: 258 QPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQH 317
PA LC + D+ + + WA+ F L ++DQM++LQ+ W E+LV R +
Sbjct: 222 LPAV-ATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPL 280
Query: 318 GKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILF 377
E L +++ L +A L L +LV +L AL+L+R+E+V LK + L
Sbjct: 281 QDE----LAFAEDLVLDEEGARAAG-LGELGAALLQLVRRLQALRLEREEYVLLKALALA 335
Query: 378 SLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGD----KFQQLLLCLVEVRALSMQA 433
+ D + + V+ +E + ALL+Y G + +LLL L +R + +
Sbjct: 336 NSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKV 395
Query: 434 KEYLYHKHLGNEMPRNNLLIEMLQA 458
+ Y L ++P + L +EML+A
Sbjct: 396 LAHFYGVKLEGKVPMHKLFLEMLEA 420
>gi|45545429 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 118 bits (296), Expect = 1e-26
Identities = 60/143 (41%), Positives = 76/143 (53%), Gaps = 7/143 (4%)
Query: 2 DYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQ 61
+Y + LC VCGD SGYHYG+ +CE+CK FFKRT+Q N Y+C + C+I K +
Sbjct: 94 EYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRR 153
Query: 62 RKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKF-------GPMYKRDRALKQQKKAQIR 114
RK C CRF KCL VGM E VR DR+RGGR K+ Y + ++ KK +
Sbjct: 154 RKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNK 213
Query: 115 ANGFKLETGPPMGVPPPPPPAPD 137
L P P P PD
Sbjct: 214 IVSHLLVAEPEKIYAMPDPTVPD 236
Score = 91.7 bits (226), Expect = 1e-18
Identities = 66/235 (28%), Positives = 119/235 (50%), Gaps = 13/235 (5%)
Query: 225 ELILQLLQLEPDEDQVRARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCM 284
+++ LL EP++ + + +PT D A LC +AD+ + I+ WA+
Sbjct: 213 KIVSHLLVAEPEK-------IYAMPDPTVPDSDIKA-LTTLCDLADRELVVIIGWAKHIP 264
Query: 285 VFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLL 344
F L +ADQM+LLQ+ W E+L+ +YR + E LV + + ++ LL
Sbjct: 265 GFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE----LVYADDYIMDEDQSKLAGLL 320
Query: 345 HSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDY 404
L +LV + +++L+++EFV LK I L + D + + V+ Q+ + AL DY
Sbjct: 321 -DLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDY 379
Query: 405 TLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAK 459
+ + ++L+ L +R S +A ++ Y+ L ++P + L +EML+AK
Sbjct: 380 EAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLEAK 434
>gi|45545427 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 118 bits (296), Expect = 1e-26
Identities = 60/143 (41%), Positives = 76/143 (53%), Gaps = 7/143 (4%)
Query: 2 DYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQ 61
+Y + LC VCGD SGYHYG+ +CE+CK FFKRT+Q N Y+C + C+I K +
Sbjct: 94 EYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRR 153
Query: 62 RKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKF-------GPMYKRDRALKQQKKAQIR 114
RK C CRF KCL VGM E VR DR+RGGR K+ Y + ++ KK +
Sbjct: 154 RKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNK 213
Query: 115 ANGFKLETGPPMGVPPPPPPAPD 137
L P P P PD
Sbjct: 214 IVSHLLVAEPEKIYAMPDPTVPD 236
Score = 91.7 bits (226), Expect = 1e-18
Identities = 66/235 (28%), Positives = 119/235 (50%), Gaps = 13/235 (5%)
Query: 225 ELILQLLQLEPDEDQVRARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCM 284
+++ LL EP++ + + +PT D A LC +AD+ + I+ WA+
Sbjct: 213 KIVSHLLVAEPEK-------IYAMPDPTVPDSDIKA-LTTLCDLADRELVVIIGWAKHIP 264
Query: 285 VFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLL 344
F L +ADQM+LLQ+ W E+L+ +YR + E LV + + ++ LL
Sbjct: 265 GFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE----LVYADDYIMDEDQSKLAGLL 320
Query: 345 HSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDY 404
L +LV + +++L+++EFV LK I L + D + + V+ Q+ + AL DY
Sbjct: 321 -DLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDY 379
Query: 405 TLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAK 459
+ + ++L+ L +R S +A ++ Y+ L ++P + L +EML+AK
Sbjct: 380 EAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLEAK 434
>gi|45545433 estrogen-related receptor gamma isoform 1 [Homo
sapiens]
Length = 458
Score = 118 bits (296), Expect = 1e-26
Identities = 60/143 (41%), Positives = 76/143 (53%), Gaps = 7/143 (4%)
Query: 2 DYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQ 61
+Y + LC VCGD SGYHYG+ +CE+CK FFKRT+Q N Y+C + C+I K +
Sbjct: 117 EYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRR 176
Query: 62 RKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKF-------GPMYKRDRALKQQKKAQIR 114
RK C CRF KCL VGM E VR DR+RGGR K+ Y + ++ KK +
Sbjct: 177 RKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNK 236
Query: 115 ANGFKLETGPPMGVPPPPPPAPD 137
L P P P PD
Sbjct: 237 IVSHLLVAEPEKIYAMPDPTVPD 259
Score = 91.7 bits (226), Expect = 1e-18
Identities = 66/235 (28%), Positives = 119/235 (50%), Gaps = 13/235 (5%)
Query: 225 ELILQLLQLEPDEDQVRARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCM 284
+++ LL EP++ + + +PT D A LC +AD+ + I+ WA+
Sbjct: 236 KIVSHLLVAEPEK-------IYAMPDPTVPDSDIKA-LTTLCDLADRELVVIIGWAKHIP 287
Query: 285 VFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLL 344
F L +ADQM+LLQ+ W E+L+ +YR + E LV + + ++ LL
Sbjct: 288 GFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE----LVYADDYIMDEDQSKLAGLL 343
Query: 345 HSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDY 404
L +LV + +++L+++EFV LK I L + D + + V+ Q+ + AL DY
Sbjct: 344 -DLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDY 402
Query: 405 TLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAK 459
+ + ++L+ L +R S +A ++ Y+ L ++P + L +EML+AK
Sbjct: 403 EAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLEAK 457
>gi|197209821 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 118 bits (296), Expect = 1e-26
Identities = 60/143 (41%), Positives = 76/143 (53%), Gaps = 7/143 (4%)
Query: 2 DYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQ 61
+Y + LC VCGD SGYHYG+ +CE+CK FFKRT+Q N Y+C + C+I K +
Sbjct: 94 EYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRR 153
Query: 62 RKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKF-------GPMYKRDRALKQQKKAQIR 114
RK C CRF KCL VGM E VR DR+RGGR K+ Y + ++ KK +
Sbjct: 154 RKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNK 213
Query: 115 ANGFKLETGPPMGVPPPPPPAPD 137
L P P P PD
Sbjct: 214 IVSHLLVAEPEKIYAMPDPTVPD 236
Score = 91.7 bits (226), Expect = 1e-18
Identities = 66/235 (28%), Positives = 119/235 (50%), Gaps = 13/235 (5%)
Query: 225 ELILQLLQLEPDEDQVRARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCM 284
+++ LL EP++ + + +PT D A LC +AD+ + I+ WA+
Sbjct: 213 KIVSHLLVAEPEK-------IYAMPDPTVPDSDIKA-LTTLCDLADRELVVIIGWAKHIP 264
Query: 285 VFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLL 344
F L +ADQM+LLQ+ W E+L+ +YR + E LV + + ++ LL
Sbjct: 265 GFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE----LVYADDYIMDEDQSKLAGLL 320
Query: 345 HSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDY 404
L +LV + +++L+++EFV LK I L + D + + V+ Q+ + AL DY
Sbjct: 321 -DLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDY 379
Query: 405 TLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAK 459
+ + ++L+ L +R S +A ++ Y+ L ++P + L +EML+AK
Sbjct: 380 EAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLEAK 434
>gi|27894344 nuclear receptor subfamily 4, group A, member 1 [Homo
sapiens]
Length = 598
Score = 113 bits (282), Expect = 4e-25
Identities = 56/114 (49%), Positives = 69/114 (60%), Gaps = 5/114 (4%)
Query: 13 CPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQK 72
C VCGD S HYG+ TCE CKGFFKRTVQ N Y C ++ C +DK +R RC FCRFQK
Sbjct: 267 CAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQK 326
Query: 73 CLTVGMRLEAVRADRMRG--GRNKFGPMYKRDRALKQQKKAQIRANGFKLETGP 124
CL VGM E VR D ++G GR P D + + +RA+ L++GP
Sbjct: 327 CLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDASPANLLTSLVRAH---LDSGP 377
Score = 44.3 bits (103), Expect = 2e-04
Identities = 42/171 (24%), Positives = 76/171 (44%), Gaps = 9/171 (5%)
Query: 279 WARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVAT 338
WA + F EL ADQ LL++ + EL + YR EG ++ +G + A
Sbjct: 420 WAEKIPGFAELSPADQDLLLESAFLELFILRLAYR--SKPGEGKLIFCSGLVLHRLQCAR 477
Query: 339 QAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKAN 398
G + S++ ++ L +L +D F CL ++L + D L V++ Q +
Sbjct: 478 GFGDWIDSILAFSR----SLHSLLVDVPAFACLSALVLIT-DRHGLQEPRRVEELQNRIA 532
Query: 399 AALLDY--TLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMP 447
+ L ++ + P +LL L E+R L Q + +++ L + +P
Sbjct: 533 SCLKEHVAAVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVP 583
>gi|21361342 nuclear receptor subfamily 4, group A, member 1 [Homo
sapiens]
Length = 598
Score = 113 bits (282), Expect = 4e-25
Identities = 56/114 (49%), Positives = 69/114 (60%), Gaps = 5/114 (4%)
Query: 13 CPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQK 72
C VCGD S HYG+ TCE CKGFFKRTVQ N Y C ++ C +DK +R RC FCRFQK
Sbjct: 267 CAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQK 326
Query: 73 CLTVGMRLEAVRADRMRG--GRNKFGPMYKRDRALKQQKKAQIRANGFKLETGP 124
CL VGM E VR D ++G GR P D + + +RA+ L++GP
Sbjct: 327 CLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDASPANLLTSLVRAH---LDSGP 377
Score = 44.3 bits (103), Expect = 2e-04
Identities = 42/171 (24%), Positives = 76/171 (44%), Gaps = 9/171 (5%)
Query: 279 WARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVAT 338
WA + F EL ADQ LL++ + EL + YR EG ++ +G + A
Sbjct: 420 WAEKIPGFAELSPADQDLLLESAFLELFILRLAYR--SKPGEGKLIFCSGLVLHRLQCAR 477
Query: 339 QAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKAN 398
G + S++ ++ L +L +D F CL ++L + D L V++ Q +
Sbjct: 478 GFGDWIDSILAFSR----SLHSLLVDVPAFACLSALVLIT-DRHGLQEPRRVEELQNRIA 532
Query: 399 AALLDY--TLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMP 447
+ L ++ + P +LL L E+R L Q + +++ L + +P
Sbjct: 533 SCLKEHVAAVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVP 583
>gi|4506755 retinoid X receptor, alpha [Homo sapiens]
Length = 462
Score = 112 bits (281), Expect = 5e-25
Identities = 45/79 (56%), Positives = 61/79 (77%)
Query: 12 LCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQ 71
+C +CGD+ SG HYG+ +CE CKGFFKRTV+ + YTC +++ C IDK QR RC +CR+Q
Sbjct: 134 ICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQ 193
Query: 72 KCLTVGMRLEAVRADRMRG 90
KCL +GM+ EAV+ +R RG
Sbjct: 194 KCLAMGMKREAVQEERQRG 212
Score = 105 bits (263), Expect = 7e-23
Identities = 70/205 (34%), Positives = 114/205 (55%), Gaps = 6/205 (2%)
Query: 254 SRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYR 313
S P+ P +C+ AD+ ++V+WA+R F EL + DQ+ LL+ W+ELL+ +R
Sbjct: 259 SSPNDPVTN--ICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHR 316
Query: 314 QVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKF 373
+ K+G ILL TG V + + + VL ELV ++ +Q+D+ E CL+
Sbjct: 317 SIAV-KDG-ILLATGLHVHRNSAHSAGVGAIFDRVLT--ELVSKMRDMQMDKTELGCLRA 372
Query: 374 IILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQA 433
I+LF+ D K L+N V+ +EK A+L Y YP +F +LLL L +R++ ++
Sbjct: 373 IVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKC 432
Query: 434 KEYLYHKHLGNEMPRNNLLIEMLQA 458
E+L+ L + P + L+EML+A
Sbjct: 433 LEHLFFFKLIGDTPIDTFLMEMLEA 457
>gi|13430848 nuclear receptor subfamily 1, group D, member 1 [Homo
sapiens]
Length = 614
Score = 112 bits (281), Expect = 5e-25
Identities = 64/161 (39%), Positives = 83/161 (51%), Gaps = 31/161 (19%)
Query: 12 LCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHY-TCTESQSCKIDKTQRKRCPFCRF 70
LC VCGD SG+HYG+ CE CKGFF+R++Q N Y C ++++C I + R RC CRF
Sbjct: 131 LCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQCRF 190
Query: 71 QKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANG-----FKLETGP- 124
+KCL+VGM +AVR R+ P ++ R L + + A AN LET P
Sbjct: 191 KKCLSVGMSRDAVRFGRI--------PKREKQRMLAEMQSAMNLANNQLSSQCPLETSPT 242
Query: 125 ------PMGVPPPPPPA----------PDYVLPPSLHGPEP 149
PMG PPP P P + PP PEP
Sbjct: 243 QHPTPGPMGPSPPPAPVPSPLVGFSQFPQQLTPPRSPSPEP 283
Score = 41.6 bits (96), Expect = 0.002
Identities = 41/163 (25%), Positives = 77/163 (47%), Gaps = 7/163 (4%)
Query: 276 IVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTT 335
+V++A+ F++L DQ+TLL+ E+L+ + + + K+ +++ ++ L
Sbjct: 450 VVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVR--FASLFNVKDQTVMFLSRTTYSLQE 507
Query: 336 V-ATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQ 394
+ A G LL ++ + +L +L L +E ++L S D + N V+ Q
Sbjct: 508 LGAMGMGDLLSAMF----DFSEKLNSLALTEEELGLFTAVVLVSADRSGMENSASVEQLQ 563
Query: 395 EKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYL 437
E AL L + P +F +LLL L ++R L+ E L
Sbjct: 564 ETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSEKL 606
>gi|5453822 nuclear receptor subfamily 4, group A, member 2 [Homo
sapiens]
Length = 598
Score = 112 bits (280), Expect = 7e-25
Identities = 47/83 (56%), Positives = 58/83 (69%)
Query: 12 LCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQ 71
LC VCGD + HYG+ TCE CKGFFKRTVQ N Y C +++C +DK +R RC +CRFQ
Sbjct: 262 LCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQ 321
Query: 72 KCLTVGMRLEAVRADRMRGGRNK 94
KCL VGM E VR D ++G R +
Sbjct: 322 KCLAVGMVKEVVRTDSLKGRRGR 344
Score = 34.7 bits (78), Expect = 0.19
Identities = 39/171 (22%), Positives = 70/171 (40%), Gaps = 9/171 (5%)
Query: 279 WARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVAT 338
WA + F +L ADQ L ++ + EL V YR + EG ++ G +
Sbjct: 420 WAEKIPGFADLPKADQDLLFESAFLELFVLRLAYR--SNPVEGKLIFCNGVVLHRLQCVR 477
Query: 339 QAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKAN 398
G + S+V E L + +D F C+ + + + + L V++ Q K
Sbjct: 478 GFGEWIDSIV----EFSSNLQNMNIDISAFSCIAALAMVT-ERHGLKEPKRVEELQNKIV 532
Query: 399 AALLDYTLCHYPHCG--DKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMP 447
L D+ + + +LL L E+R L Q + +++ L + +P
Sbjct: 533 NCLKDHVTFNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVP 583
>gi|27894361 nuclear receptor subfamily 4, group A, member 3 isoform
b [Homo sapiens]
Length = 637
Score = 112 bits (280), Expect = 7e-25
Identities = 58/140 (41%), Positives = 75/140 (53%), Gaps = 17/140 (12%)
Query: 13 CPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQK 72
C VCGD + HYG+ TCE CKGFFKRTVQ N Y C +++C +DK +R RC +CRFQK
Sbjct: 303 CAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQK 362
Query: 73 CLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPP 132
CL+VGM E VR D ++G R + L + K+ L+ P PP P
Sbjct: 363 CLSVGMVKEVVRTDSLKGRRGR----------LPSKPKS-------PLQQEPSQPSPPSP 405
Query: 133 PPAPDYVLPPSLHGPEPKGL 152
P L +L P+ L
Sbjct: 406 PICMMNALVRALTDSTPRDL 425
>gi|27894359 nuclear receptor subfamily 4, group A, member 3 isoform
c [Homo sapiens]
Length = 443
Score = 112 bits (280), Expect = 7e-25
Identities = 58/140 (41%), Positives = 75/140 (53%), Gaps = 17/140 (12%)
Query: 13 CPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQK 72
C VCGD + HYG+ TCE CKGFFKRTVQ N Y C +++C +DK +R RC +CRFQK
Sbjct: 292 CAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQK 351
Query: 73 CLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPP 132
CL+VGM E VR D ++G R + L + K+ L+ P PP P
Sbjct: 352 CLSVGMVKEVVRTDSLKGRRGR----------LPSKPKS-------PLQQEPSQPSPPSP 394
Query: 133 PPAPDYVLPPSLHGPEPKGL 152
P L +L P+ L
Sbjct: 395 PICMMNALVRALTDSTPRDL 414
>gi|27894357 nuclear receptor subfamily 4, group A, member 3 isoform
a [Homo sapiens]
Length = 626
Score = 112 bits (280), Expect = 7e-25
Identities = 58/140 (41%), Positives = 75/140 (53%), Gaps = 17/140 (12%)
Query: 13 CPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQK 72
C VCGD + HYG+ TCE CKGFFKRTVQ N Y C +++C +DK +R RC +CRFQK
Sbjct: 292 CAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQK 351
Query: 73 CLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPP 132
CL+VGM E VR D ++G R + L + K+ L+ P PP P
Sbjct: 352 CLSVGMVKEVVRTDSLKGRRGR----------LPSKPKS-------PLQQEPSQPSPPSP 394
Query: 133 PPAPDYVLPPSLHGPEPKGL 152
P L +L P+ L
Sbjct: 395 PICMMNALVRALTDSTPRDL 414
>gi|27894355 nuclear receptor subfamily 4, group A, member 3 isoform
a [Homo sapiens]
Length = 626
Score = 112 bits (280), Expect = 7e-25
Identities = 58/140 (41%), Positives = 75/140 (53%), Gaps = 17/140 (12%)
Query: 13 CPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQK 72
C VCGD + HYG+ TCE CKGFFKRTVQ N Y C +++C +DK +R RC +CRFQK
Sbjct: 292 CAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQK 351
Query: 73 CLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPP 132
CL+VGM E VR D ++G R + L + K+ L+ P PP P
Sbjct: 352 CLSVGMVKEVVRTDSLKGRRGR----------LPSKPKS-------PLQQEPSQPSPPSP 394
Query: 133 PPAPDYVLPPSLHGPEPKGL 152
P L +L P+ L
Sbjct: 395 PICMMNALVRALTDSTPRDL 414
>gi|11415052 retinoid X receptor, beta [Homo sapiens]
Length = 533
Score = 111 bits (277), Expect = 2e-24
Identities = 43/79 (54%), Positives = 60/79 (75%)
Query: 12 LCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQ 71
LC +CGD+ SG HYG+ +CE CKGFFKRT++ + Y+C +++ C +DK QR RC +CR+Q
Sbjct: 204 LCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQ 263
Query: 72 KCLTVGMRLEAVRADRMRG 90
KCL GM+ EAV+ +R RG
Sbjct: 264 KCLATGMKREAVQEERQRG 282
Score = 102 bits (254), Expect = 7e-22
Identities = 67/205 (32%), Positives = 110/205 (53%), Gaps = 6/205 (2%)
Query: 254 SRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYR 313
S P+ P +C+ AD+ ++V+WA+R F L + DQ+ LL+ W+ELL+ +R
Sbjct: 330 SSPNDPVTN--ICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHR 387
Query: 314 QVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKF 373
+ ILL TG V + + + VL ELV ++ +++D+ E CL+
Sbjct: 388 SID--VRDGILLATGLHVHRNSAHSAGVGAIFDRVLT--ELVSKMRDMRMDKTELGCLRA 443
Query: 374 IILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQA 433
IILF+ D K L+N V+ +EK A+L Y YP +F +LLL L +R++ ++
Sbjct: 444 IILFNPDAKGLSNPSEVEVLREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKC 503
Query: 434 KEYLYHKHLGNEMPRNNLLIEMLQA 458
E+L+ L + P + L+EML+A
Sbjct: 504 LEHLFFFKLIGDTPIDTFLMEMLEA 528
Score = 42.4 bits (98), Expect = 9e-04
Identities = 38/110 (34%), Positives = 44/110 (40%), Gaps = 16/110 (14%)
Query: 125 PMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGP----PAGPLG--------DFGAPAL-PM 171
P GVPPP PP P LPPS P G A P P PLG G+P L P
Sbjct: 92 PQGVPPPSPPGPP--LPPST-APSLGGSGAPPPPPMPPPPLGSPFPVISSSMGSPGLPPP 148
Query: 172 AVPGAHGPLAGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGP 221
A PG GP++ + P PP G+ + P GGP
Sbjct: 149 APPGFSGPVSSPQINSTVSLPGGGSGPPEDVKPPVLGVRGLHCPPPPGGP 198
Score = 32.0 bits (71), Expect = 1.2
Identities = 27/90 (30%), Positives = 34/90 (37%), Gaps = 14/90 (15%)
Query: 124 PPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVP---GAHGPL 180
PP +PPPP +P V+ S+ P GL P G G +P + V G GP
Sbjct: 120 PPPPMPPPPLGSPFPVISSSMGSP---GLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPP 176
Query: 181 AGYLYPAFPGRAIKSEYPEPYASPPQPGLP 210
P R + PP PG P
Sbjct: 177 EDVKPPVLGVRGLH--------CPPPPGGP 198
>gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens]
Length = 463
Score = 109 bits (273), Expect = 5e-24
Identities = 43/78 (55%), Positives = 60/78 (76%)
Query: 12 LCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQ 71
+C +CGD+ SG HYG+ +CE CKGFFKRT++ + YTC +++ C IDK QR RC +CR+Q
Sbjct: 138 ICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQ 197
Query: 72 KCLTVGMRLEAVRADRMR 89
KCL +GM+ EAV+ +R R
Sbjct: 198 KCLVMGMKREAVQEERQR 215
Score = 105 bits (263), Expect = 7e-23
Identities = 65/193 (33%), Positives = 107/193 (55%), Gaps = 4/193 (2%)
Query: 265 LCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSIL 324
+C AD+ ++V+WA+R F +L + DQ+ LL+ W+ELL+ +R V + IL
Sbjct: 269 ICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVS--VQDGIL 326
Query: 325 LVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFL 384
L TG V ++ + + VL ELV ++ +Q+D+ E CL+ I+LF+ D K L
Sbjct: 327 LATGLHVHRSSAHSAGVGSIFDRVLT--ELVSKMKDMQMDKSELGCLRAIVLFNPDAKGL 384
Query: 385 NNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGN 444
+N V+ +EK A L YT YP +F +LLL L +R++ ++ E+L+ L
Sbjct: 385 SNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIG 444
Query: 445 EMPRNNLLIEMLQ 457
+ P + L+EML+
Sbjct: 445 DTPIDTFLMEMLE 457
>gi|19743907 RAR-related orphan receptor B [Homo sapiens]
Length = 459
Score = 109 bits (272), Expect = 6e-24
Identities = 47/102 (46%), Positives = 68/102 (66%), Gaps = 2/102 (1%)
Query: 13 CPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQK 72
C +CGDK SG HYG++TCE CKGFF+R+ QNN Y+C ++C ID+T R RC CR QK
Sbjct: 10 CKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRNRCQHCRLQK 69
Query: 73 CLTVGMRLEAVRADRM--RGGRNKFGPMYKRDRALKQQKKAQ 112
CL +GM +AV+ RM + + + + K + L++Q++ Q
Sbjct: 70 CLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQRLQEQRQQQ 111
>gi|19743905 RAR-related orphan receptor A isoform d [Homo sapiens]
Length = 468
Score = 108 bits (269), Expect = 1e-23
Identities = 119/449 (26%), Positives = 176/449 (39%), Gaps = 57/449 (12%)
Query: 13 CPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQK 72
C +CGDK SG HYG++TCE CKGFF+R+ Q+N Y+C ++C ID+T R RC CR QK
Sbjct: 18 CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQK 77
Query: 73 CLTVGMRLEAVRADRMRGGRNKFGPMYKRDR----ALKQQKKAQIRANGFKLETGPPMGV 128
CL VGM +AV KFG M K+ R A Q+ + Q + + + G
Sbjct: 78 CLAVGMSRDAV----------KFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPG----- 122
Query: 129 PPPPPPAPDYVLPPS----LHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPLAGYL 184
P P Y + + LH + P G D + + + +
Sbjct: 123 -EAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPS-------- 173
Query: 185 YPAFPGRAIKSEYPEPYA--SPPQPGLPY-----GYPEPFSG-------GPNVPELILQL 230
P G I PEP +P PY G P N+ + L+
Sbjct: 174 -PDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLET 232
Query: 231 LQLEPDEDQVRARILGCLQEPTKSRPDQPAAFGLLCRMADQTFIS-IVDWARRCMVFKEL 289
Q +E Q +E + Q LC + I +V++A+R F EL
Sbjct: 233 CQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMEL 292
Query: 290 EVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVL 349
DQ+ LL+ S +VF + R + + + G+ + S V
Sbjct: 293 CQNDQIVLLK-AGSLEVVFIRMCRAFD--SQNNTVYFDGKYASPDVFKSLGCEDFISFVF 349
Query: 350 RAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHY 409
E L ++ L E +L S D +L + ++ Q+K AL +
Sbjct: 350 ---EFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLAL--QHVLQK 404
Query: 410 PHCGDKFQQLLLCLVE-VRALSMQAKEYL 437
H D L+C V +RAL + E L
Sbjct: 405 NHREDGILTKLICKVSTLRALCGRHTEKL 433
>gi|4506577 RAR-related orphan receptor A isoform c [Homo sapiens]
Length = 548
Score = 108 bits (269), Expect = 1e-23
Identities = 119/449 (26%), Positives = 176/449 (39%), Gaps = 57/449 (12%)
Query: 13 CPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQK 72
C +CGDK SG HYG++TCE CKGFF+R+ Q+N Y+C ++C ID+T R RC CR QK
Sbjct: 98 CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQK 157
Query: 73 CLTVGMRLEAVRADRMRGGRNKFGPMYKRDR----ALKQQKKAQIRANGFKLETGPPMGV 128
CL VGM +AV KFG M K+ R A Q+ + Q + + + G
Sbjct: 158 CLAVGMSRDAV----------KFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPG----- 202
Query: 129 PPPPPPAPDYVLPPS----LHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPLAGYL 184
P P Y + + LH + P G D + + + +
Sbjct: 203 -EAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPS-------- 253
Query: 185 YPAFPGRAIKSEYPEPYA--SPPQPGLPY-----GYPEPFSG-------GPNVPELILQL 230
P G I PEP +P PY G P N+ + L+
Sbjct: 254 -PDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLET 312
Query: 231 LQLEPDEDQVRARILGCLQEPTKSRPDQPAAFGLLCRMADQTFIS-IVDWARRCMVFKEL 289
Q +E Q +E + Q LC + I +V++A+R F EL
Sbjct: 313 CQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMEL 372
Query: 290 EVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVL 349
DQ+ LL+ S +VF + R + + + G+ + S V
Sbjct: 373 CQNDQIVLLK-AGSLEVVFIRMCRAFD--SQNNTVYFDGKYASPDVFKSLGCEDFISFVF 429
Query: 350 RAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHY 409
E L ++ L E +L S D +L + ++ Q+K AL +
Sbjct: 430 ---EFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLAL--QHVLQK 484
Query: 410 PHCGDKFQQLLLCLVE-VRALSMQAKEYL 437
H D L+C V +RAL + E L
Sbjct: 485 NHREDGILTKLICKVSTLRALCGRHTEKL 513
>gi|19743901 RAR-related orphan receptor A isoform b [Homo sapiens]
Length = 556
Score = 108 bits (269), Expect = 1e-23
Identities = 119/449 (26%), Positives = 176/449 (39%), Gaps = 57/449 (12%)
Query: 13 CPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQK 72
C +CGDK SG HYG++TCE CKGFF+R+ Q+N Y+C ++C ID+T R RC CR QK
Sbjct: 106 CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQK 165
Query: 73 CLTVGMRLEAVRADRMRGGRNKFGPMYKRDR----ALKQQKKAQIRANGFKLETGPPMGV 128
CL VGM +AV KFG M K+ R A Q+ + Q + + + G
Sbjct: 166 CLAVGMSRDAV----------KFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPG----- 210
Query: 129 PPPPPPAPDYVLPPS----LHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPLAGYL 184
P P Y + + LH + P G D + + + +
Sbjct: 211 -EAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPS-------- 261
Query: 185 YPAFPGRAIKSEYPEPYA--SPPQPGLPY-----GYPEPFSG-------GPNVPELILQL 230
P G I PEP +P PY G P N+ + L+
Sbjct: 262 -PDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLET 320
Query: 231 LQLEPDEDQVRARILGCLQEPTKSRPDQPAAFGLLCRMADQTFIS-IVDWARRCMVFKEL 289
Q +E Q +E + Q LC + I +V++A+R F EL
Sbjct: 321 CQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMEL 380
Query: 290 EVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVL 349
DQ+ LL+ S +VF + R + + + G+ + S V
Sbjct: 381 CQNDQIVLLK-AGSLEVVFIRMCRAFD--SQNNTVYFDGKYASPDVFKSLGCEDFISFVF 437
Query: 350 RAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHY 409
E L ++ L E +L S D +L + ++ Q+K AL +
Sbjct: 438 ---EFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLAL--QHVLQK 492
Query: 410 PHCGDKFQQLLLCLVE-VRALSMQAKEYL 437
H D L+C V +RAL + E L
Sbjct: 493 NHREDGILTKLICKVSTLRALCGRHTEKL 521
>gi|19743903 RAR-related orphan receptor A isoform a [Homo sapiens]
Length = 523
Score = 108 bits (269), Expect = 1e-23
Identities = 119/449 (26%), Positives = 176/449 (39%), Gaps = 57/449 (12%)
Query: 13 CPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQK 72
C +CGDK SG HYG++TCE CKGFF+R+ Q+N Y+C ++C ID+T R RC CR QK
Sbjct: 73 CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQK 132
Query: 73 CLTVGMRLEAVRADRMRGGRNKFGPMYKRDR----ALKQQKKAQIRANGFKLETGPPMGV 128
CL VGM +AV KFG M K+ R A Q+ + Q + + + G
Sbjct: 133 CLAVGMSRDAV----------KFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPG----- 177
Query: 129 PPPPPPAPDYVLPPS----LHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPLAGYL 184
P P Y + + LH + P G D + + + +
Sbjct: 178 -EAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPS-------- 228
Query: 185 YPAFPGRAIKSEYPEPYA--SPPQPGLPY-----GYPEPFSG-------GPNVPELILQL 230
P G I PEP +P PY G P N+ + L+
Sbjct: 229 -PDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLET 287
Query: 231 LQLEPDEDQVRARILGCLQEPTKSRPDQPAAFGLLCRMADQTFIS-IVDWARRCMVFKEL 289
Q +E Q +E + Q LC + I +V++A+R F EL
Sbjct: 288 CQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMEL 347
Query: 290 EVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVL 349
DQ+ LL+ S +VF + R + + + G+ + S V
Sbjct: 348 CQNDQIVLLK-AGSLEVVFIRMCRAFD--SQNNTVYFDGKYASPDVFKSLGCEDFISFVF 404
Query: 350 RAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHY 409
E L ++ L E +L S D +L + ++ Q+K AL +
Sbjct: 405 ---EFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLAL--QHVLQK 459
Query: 410 PHCGDKFQQLLLCLVE-VRALSMQAKEYL 437
H D L+C V +RAL + E L
Sbjct: 460 NHREDGILTKLICKVSTLRALCGRHTEKL 488
>gi|48255918 RAR-related orphan receptor C isoform b [Homo sapiens]
Length = 497
Score = 106 bits (264), Expect = 5e-23
Identities = 63/163 (38%), Positives = 82/163 (50%), Gaps = 27/163 (16%)
Query: 13 CPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQK 72
C +CGDK SG HYG++TCE CKGFF+R+ + N Y+CT Q+C ID+T R RC CR QK
Sbjct: 10 CKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNRCQHCRLQK 69
Query: 73 CLTVGMRLEAVRADRMRGGRNKFGPMYKRDR---ALKQQKKAQIRANGFKLETGPPMGVP 129
CL +GM +AV KFG M K+ R + QK+ Q R + + P + P
Sbjct: 70 CLALGMSRDAV----------KFGRMSKKQRDSLHAEVQKQLQQRQ---QQQQEPVVKTP 116
Query: 130 PPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMA 172
P G + G P G L +P LP A
Sbjct: 117 -----------PAGAQGADTLTYTLGLPDGQLPLGSSPDLPEA 148
>gi|19743909 RAR-related orphan receptor C isoform a [Homo sapiens]
Length = 518
Score = 106 bits (264), Expect = 5e-23
Identities = 63/163 (38%), Positives = 82/163 (50%), Gaps = 27/163 (16%)
Query: 13 CPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQK 72
C +CGDK SG HYG++TCE CKGFF+R+ + N Y+CT Q+C ID+T R RC CR QK
Sbjct: 31 CKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNRCQHCRLQK 90
Query: 73 CLTVGMRLEAVRADRMRGGRNKFGPMYKRDR---ALKQQKKAQIRANGFKLETGPPMGVP 129
CL +GM +AV KFG M K+ R + QK+ Q R + + P + P
Sbjct: 91 CLALGMSRDAV----------KFGRMSKKQRDSLHAEVQKQLQQRQ---QQQQEPVVKTP 137
Query: 130 PPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMA 172
P G + G P G L +P LP A
Sbjct: 138 -----------PAGAQGADTLTYTLGLPDGQLPLGSSPDLPEA 169
>gi|40806160 thyroid hormone receptor, alpha isoform 1 [Homo
sapiens]
Length = 410
Score = 105 bits (263), Expect = 7e-23
Identities = 49/103 (47%), Positives = 63/103 (61%), Gaps = 3/103 (2%)
Query: 8 DLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKH--YTCTESQSCKIDKTQRKRC 65
D DE C VCGDK +GYHY +TCE CKGFF+RT+Q N H Y+C C IDK R +C
Sbjct: 48 DKDEQCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQC 107
Query: 66 PFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQ 108
CRF+KC+ VGM ++ V D R + K R+R K++
Sbjct: 108 QLCRFKKCIAVGMAMDLVLDDSKRVAKRKLIEQ-NRERRRKEE 149
Score = 45.4 bits (106), Expect = 1e-04
Identities = 51/201 (25%), Positives = 88/201 (43%), Gaps = 18/201 (8%)
Query: 249 QEPTKSRPDQPA----AFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSE 304
Q P S PD AF ++ +VD+A++ +F EL DQ+ LL+ C E
Sbjct: 198 QSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFSELPCEDQIILLKGCCME 257
Query: 305 LLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLD 364
++ + V++ E L ++G+ G + S + EL L A LD
Sbjct: 258 IM---SLRAAVRYDPESDTLTLSGEMAVKREQLKNGGLGVVSDAI--FELGKSLSAFNLD 312
Query: 365 RQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALL---DYTLCHYPHCGDKF-QQLL 420
E L+ ++L S D + +L D EK+ A L ++ + H H F +LL
Sbjct: 313 DTEVALLQAVLLMSTD----RSGLLCVDKIEKSQEAYLLAFEHYVNHRKHNIPHFWPKLL 368
Query: 421 LCLVEVRAL-SMQAKEYLYHK 440
+ + ++R + + A +L+ K
Sbjct: 369 MKVTDLRMIGACHASRFLHMK 389
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.140 0.437
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,958,057
Number of Sequences: 37866
Number of extensions: 1388634
Number of successful extensions: 17074
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 329
Number of HSP's successfully gapped in prelim test: 865
Number of HSP's that attempted gapping in prelim test: 8893
Number of HSP's gapped (non-prelim): 5018
length of query: 461
length of database: 18,247,518
effective HSP length: 106
effective length of query: 355
effective length of database: 14,233,722
effective search space: 5052971310
effective search space used: 5052971310
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.