BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|19924101 synapsin II isoform IIb [Homo sapiens] (478 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|19924101 synapsin II isoform IIb [Homo sapiens] 974 0.0 gi|19924103 synapsin II isoform IIa [Homo sapiens] 931 0.0 gi|19924099 synapsin I isoform Ia [Homo sapiens] 615 e-176 gi|19924097 synapsin I isoform Ib [Homo sapiens] 615 e-176 gi|209413756 synapsin III isoform IIIg [Homo sapiens] 578 e-165 gi|209413752 synapsin III isoform IIIa [Homo sapiens] 573 e-164 gi|209413754 synapsin III isoform IIIc [Homo sapiens] 571 e-163 gi|110832843 TBP-associated factor 4 [Homo sapiens] 55 2e-07 gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 54 2e-07 gi|153792074 proline rich 12 [Homo sapiens] 54 4e-07 gi|210031233 PR domain containing 6 [Homo sapiens] 51 3e-06 gi|33356148 formin-like 1 [Homo sapiens] 51 3e-06 gi|226498192 atonal homolog 8 [Homo sapiens] 50 5e-06 gi|38683860 insulin receptor substrate 2 [Homo sapiens] 50 5e-06 gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 50 5e-06 gi|56549694 enabled homolog isoform a [Homo sapiens] 49 8e-06 gi|39930375 enabled homolog isoform b [Homo sapiens] 49 8e-06 gi|18079216 CASK interacting protein 1 [Homo sapiens] 49 1e-05 gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 49 1e-05 gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 49 1e-05 gi|145309324 FH2 domain containing 1 [Homo sapiens] 49 1e-05 gi|14149904 anthrax toxin receptor 1 isoform 1 precursor [Homo s... 49 1e-05 gi|11386183 WAS protein family, member 2 [Homo sapiens] 48 2e-05 gi|62000702 diacylglycerol kinase kappa [Homo sapiens] 48 2e-05 gi|62945417 dystrophia myotonica-containing WD repeat motif prot... 48 2e-05 gi|90903231 huntingtin [Homo sapiens] 48 2e-05 gi|4503519 eukaryotic translation initiation factor 3, subunit 5... 48 2e-05 gi|52485606 formin-like 2 [Homo sapiens] 48 2e-05 gi|110556644 zinc finger protein, multitype 1 [Homo sapiens] 48 2e-05 gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho... 47 3e-05 >gi|19924101 synapsin II isoform IIb [Homo sapiens] Length = 478 Score = 974 bits (2517), Expect = 0.0 Identities = 478/478 (100%), Positives = 478/478 (100%) Query: 1 MMNFLRRRLSDSSFIANLPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPER 60 MMNFLRRRLSDSSFIANLPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPER Sbjct: 1 MMNFLRRRLSDSSFIANLPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPER 60 Query: 61 RPPPASAPAPQPAPTPSVGSSFFSSLSQAVKQTAASAGLVDAPAPAPAAARKAKVLLVVD 120 RPPPASAPAPQPAPTPSVGSSFFSSLSQAVKQTAASAGLVDAPAPAPAAARKAKVLLVVD Sbjct: 61 RPPPASAPAPQPAPTPSVGSSFFSSLSQAVKQTAASAGLVDAPAPAPAAARKAKVLLVVD 120 Query: 121 EPHADWAKCFRGKKVLGDYDIKVEQAEFSELNLVAHADGTYAVDMQVLRNGTKVVRSFRP 180 EPHADWAKCFRGKKVLGDYDIKVEQAEFSELNLVAHADGTYAVDMQVLRNGTKVVRSFRP Sbjct: 121 EPHADWAKCFRGKKVLGDYDIKVEQAEFSELNLVAHADGTYAVDMQVLRNGTKVVRSFRP 180 Query: 181 DFVLIRQHAFGMAENEDFRHLIIGMQYAGLPSINSLESIYNFCDKPWVFAQLVAIYKTLG 240 DFVLIRQHAFGMAENEDFRHLIIGMQYAGLPSINSLESIYNFCDKPWVFAQLVAIYKTLG Sbjct: 181 DFVLIRQHAFGMAENEDFRHLIIGMQYAGLPSINSLESIYNFCDKPWVFAQLVAIYKTLG 240 Query: 241 GEKFPLIEQTYYPNHKEMLTLPTFPVVVKIGHAHSGMGKVKVENHYDFQDIASVVALTQT 300 GEKFPLIEQTYYPNHKEMLTLPTFPVVVKIGHAHSGMGKVKVENHYDFQDIASVVALTQT Sbjct: 241 GEKFPLIEQTYYPNHKEMLTLPTFPVVVKIGHAHSGMGKVKVENHYDFQDIASVVALTQT 300 Query: 301 YATAEPFIDSKYDIRVQKIGNNYKAYMRTSISGNWKTNTGSAMLEQIAMSDRYKLWVDTC 360 YATAEPFIDSKYDIRVQKIGNNYKAYMRTSISGNWKTNTGSAMLEQIAMSDRYKLWVDTC Sbjct: 301 YATAEPFIDSKYDIRVQKIGNNYKAYMRTSISGNWKTNTGSAMLEQIAMSDRYKLWVDTC 360 Query: 361 SEMFGGLDICAVKAVHGKDGKDYIFEVMDCSMPLIGEHQVEDRQLITELVISKMNQLLSR 420 SEMFGGLDICAVKAVHGKDGKDYIFEVMDCSMPLIGEHQVEDRQLITELVISKMNQLLSR Sbjct: 361 SEMFGGLDICAVKAVHGKDGKDYIFEVMDCSMPLIGEHQVEDRQLITELVISKMNQLLSR 420 Query: 421 TPALSPQRPLTTQQPQSGTLKDPDSSKTPPQRPPPQGCLQYILDCNGIAVGPKQVQAS 478 TPALSPQRPLTTQQPQSGTLKDPDSSKTPPQRPPPQGCLQYILDCNGIAVGPKQVQAS Sbjct: 421 TPALSPQRPLTTQQPQSGTLKDPDSSKTPPQRPPPQGCLQYILDCNGIAVGPKQVQAS 478 >gi|19924103 synapsin II isoform IIa [Homo sapiens] Length = 582 Score = 931 bits (2405), Expect = 0.0 Identities = 457/457 (100%), Positives = 457/457 (100%) Query: 1 MMNFLRRRLSDSSFIANLPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPER 60 MMNFLRRRLSDSSFIANLPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPER Sbjct: 1 MMNFLRRRLSDSSFIANLPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPER 60 Query: 61 RPPPASAPAPQPAPTPSVGSSFFSSLSQAVKQTAASAGLVDAPAPAPAAARKAKVLLVVD 120 RPPPASAPAPQPAPTPSVGSSFFSSLSQAVKQTAASAGLVDAPAPAPAAARKAKVLLVVD Sbjct: 61 RPPPASAPAPQPAPTPSVGSSFFSSLSQAVKQTAASAGLVDAPAPAPAAARKAKVLLVVD 120 Query: 121 EPHADWAKCFRGKKVLGDYDIKVEQAEFSELNLVAHADGTYAVDMQVLRNGTKVVRSFRP 180 EPHADWAKCFRGKKVLGDYDIKVEQAEFSELNLVAHADGTYAVDMQVLRNGTKVVRSFRP Sbjct: 121 EPHADWAKCFRGKKVLGDYDIKVEQAEFSELNLVAHADGTYAVDMQVLRNGTKVVRSFRP 180 Query: 181 DFVLIRQHAFGMAENEDFRHLIIGMQYAGLPSINSLESIYNFCDKPWVFAQLVAIYKTLG 240 DFVLIRQHAFGMAENEDFRHLIIGMQYAGLPSINSLESIYNFCDKPWVFAQLVAIYKTLG Sbjct: 181 DFVLIRQHAFGMAENEDFRHLIIGMQYAGLPSINSLESIYNFCDKPWVFAQLVAIYKTLG 240 Query: 241 GEKFPLIEQTYYPNHKEMLTLPTFPVVVKIGHAHSGMGKVKVENHYDFQDIASVVALTQT 300 GEKFPLIEQTYYPNHKEMLTLPTFPVVVKIGHAHSGMGKVKVENHYDFQDIASVVALTQT Sbjct: 241 GEKFPLIEQTYYPNHKEMLTLPTFPVVVKIGHAHSGMGKVKVENHYDFQDIASVVALTQT 300 Query: 301 YATAEPFIDSKYDIRVQKIGNNYKAYMRTSISGNWKTNTGSAMLEQIAMSDRYKLWVDTC 360 YATAEPFIDSKYDIRVQKIGNNYKAYMRTSISGNWKTNTGSAMLEQIAMSDRYKLWVDTC Sbjct: 301 YATAEPFIDSKYDIRVQKIGNNYKAYMRTSISGNWKTNTGSAMLEQIAMSDRYKLWVDTC 360 Query: 361 SEMFGGLDICAVKAVHGKDGKDYIFEVMDCSMPLIGEHQVEDRQLITELVISKMNQLLSR 420 SEMFGGLDICAVKAVHGKDGKDYIFEVMDCSMPLIGEHQVEDRQLITELVISKMNQLLSR Sbjct: 361 SEMFGGLDICAVKAVHGKDGKDYIFEVMDCSMPLIGEHQVEDRQLITELVISKMNQLLSR 420 Query: 421 TPALSPQRPLTTQQPQSGTLKDPDSSKTPPQRPPPQG 457 TPALSPQRPLTTQQPQSGTLKDPDSSKTPPQRPPPQG Sbjct: 421 TPALSPQRPLTTQQPQSGTLKDPDSSKTPPQRPPPQG 457 Score = 35.0 bits (79), Expect = 0.15 Identities = 32/113 (28%), Positives = 45/113 (39%), Gaps = 37/113 (32%) Query: 19 PNGYMTDLQRPEPQ---------QPPP---PP---PPGPGAASASAAPPTASPGPERRP- 62 P+ T QRP PQ QPP PP PPGP +S++ ++S +RP Sbjct: 443 PDSSKTPPQRPPPQGGPGQPQGMQPPGKVLPPRRLPPGPSLPPSSSSSSSSSSSAPQRPG 502 Query: 63 -------------------PPASAPAPQPAPTPSVGSSFFSSLSQAVKQTAAS 96 PP +AP +P P P + S SL+ A + +S Sbjct: 503 GPTTHGDAPSSSSSLAEAQPPLAAPPQKPQPHPQLNKS--QSLTNAFSFSESS 553 Score = 33.1 bits (74), Expect = 0.57 Identities = 28/95 (29%), Positives = 37/95 (38%), Gaps = 12/95 (12%) Query: 26 LQRPEPQQPPPP-PPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVGSSFFS 84 L+ P+ + PP PPP G P P RR P P P P+ S SS S Sbjct: 440 LKDPDSSKTPPQRPPPQGGPGQPQGMQPPGKVLPPRRLP----PGPSLPPSSSSSSSSSS 495 Query: 85 SLSQAV-------KQTAASAGLVDAPAPAPAAARK 112 S Q ++S+ L +A P A +K Sbjct: 496 SAPQRPGGPTTHGDAPSSSSSLAEAQPPLAAPPQK 530 Score = 32.7 bits (73), Expect = 0.74 Identities = 32/120 (26%), Positives = 43/120 (35%), Gaps = 17/120 (14%) Query: 8 RLSDSSFIANLPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASA 67 ++ D I L M L P P P S + P +S P +RPPP Sbjct: 399 QVEDRQLITELVISKMNQLLSRTPALSPQRPLTTQQPQSGTLKDPDSSKTPPQRPPPQGG 458 Query: 68 PA-PQ---------------PAPT-PSVGSSFFSSLSQAVKQTAASAGLVDAPAPAPAAA 110 P PQ P P+ P SS SS S A ++ DAP+ + + A Sbjct: 459 PGQPQGMQPPGKVLPPRRLPPGPSLPPSSSSSSSSSSSAPQRPGGPTTHGDAPSSSSSLA 518 >gi|19924099 synapsin I isoform Ia [Homo sapiens] Length = 705 Score = 615 bits (1586), Expect = e-176 Identities = 312/470 (66%), Positives = 367/470 (78%), Gaps = 19/470 (4%) Query: 2 MNFLRRRLSDSSFIANLPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPERR 61 MN+LRRRLSDS+F+ANLPNGYMTDLQRP+P PPPPPG + A+ P TA+ Sbjct: 1 MNYLRRRLSDSNFMANLPNGYMTDLQRPQP----PPPPPGAHSPGATPGPGTATAERSSG 56 Query: 62 PPPASAPAPQPAPTPSVGSSFFSSLSQAVKQTAASAGLV------DAPAPAPAAARKAKV 115 PA++PA P+P S G FFSSLS AVKQT A+A A ++V Sbjct: 57 VAPAASPAA-PSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAASRV 115 Query: 116 LLVVDEPHADWAKCFRGKKVLGDYDIKVEQAEFSELNLVAHADGTYAVDMQVLRNGTKVV 175 LLV+DEPH DWAK F+GKK+ G+ DIKVEQAEFS+LNLVAHA+G ++VDM+VLRNG KVV Sbjct: 116 LLVIDEPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVV 175 Query: 176 RSFRPDFVLIRQHAFGMAENEDFRHLIIGMQYAGLPSINSLESIYNFCDKPWVFAQLVAI 235 RS +PDFVLIRQHAF MA N D+R L+IG+QYAG+PS+NSL S+YNFCDKPWVFAQ+V + Sbjct: 176 RSLKPDFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRL 235 Query: 236 YKTLGGEKFPLIEQTYYPNHKEMLTLPTFPVVVKIGHAHSGMGKVKVENHYDFQDIASVV 295 +K LG E+FPLI+QT+YPNHKEML+ T+PVVVK+GHAHSGMGKVKV+N +DFQDIASVV Sbjct: 236 HKKLGTEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVV 295 Query: 296 ALTQTYATAEPFIDSKYDIRVQKIGNNYKAYMRTSISGNWKTNTGSAMLEQIAMSDRYKL 355 ALT+TYATAEPFID+KYD+RVQKIG NYKAYMRTS+SGNWKTNTGSAMLEQIAMSDRYKL Sbjct: 296 ALTKTYATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKL 355 Query: 356 WVDTCSEMFGGLDICAVKAVHGKDGKDYIFEVMDCSMPLIGEHQVEDRQLITELVISKMN 415 WVDTCSE+FGGLDICAV+A+HGKDG+D+I EV+ SMPLIG+HQ ED+QLI ELV++KM Sbjct: 356 WVDTCSEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMA 415 Query: 416 QLL--SRTPALSPQRPLTTQQPQSGTL----KDPDSSKTPP--QRPPPQG 457 Q L R SP R Q P G L + PP QRPPPQG Sbjct: 416 QALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQG 465 Score = 42.0 bits (97), Expect = 0.001 Identities = 26/66 (39%), Positives = 28/66 (42%), Gaps = 18/66 (27%) Query: 27 QRPEPQQPPPPPPPGPGAAS---------------ASAAPPTASPGPERRPPPASA---P 68 QRP PQ PP P PGP + PP SP P+R P P SA P Sbjct: 459 QRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQP 518 Query: 69 APQPAP 74 A Q AP Sbjct: 519 ASQAAP 524 Score = 41.2 bits (95), Expect = 0.002 Identities = 30/88 (34%), Positives = 39/88 (44%), Gaps = 19/88 (21%) Query: 29 PEPQQPPPPPPPGPGAASASAAPPTASPGPERRP-------PPASAPAPQPAPTPSVGSS 81 P PQ+ P P P ++ AAPPT G + RP PPA+ P P+P G Sbjct: 503 PLPQRL-PSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGP- 560 Query: 82 FFSSLSQAVKQTAASAGLVDAPAPAPAA 109 QA +QT+ V PAP A+ Sbjct: 561 -----PQATRQTS-----VSGPAPPKAS 578 Score = 38.1 bits (87), Expect = 0.018 Identities = 36/115 (31%), Positives = 42/115 (36%), Gaps = 33/115 (28%) Query: 18 LPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPER-------RP-------- 62 LP G T Q P PPP G PP PGP+R RP Sbjct: 442 LPLGRQTSQQPAGPPAQQRPPPQG--------GPPQPGPGPQRQGPPLQQRPPPQGQQHL 493 Query: 63 ----PPASAPAPQPAPTPSVGSSFFSSLSQAVKQTAA----SAGLVDAPAPAPAA 109 PPA +P PQ P+P+ S+ SQA T S + P PAA Sbjct: 494 SGLGPPAGSPLPQRLPSPT--SAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAA 546 Score = 37.0 bits (84), Expect = 0.039 Identities = 26/80 (32%), Positives = 32/80 (40%), Gaps = 18/80 (22%) Query: 31 PQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVGSSFFSSLSQAV 90 PQ+PP P P A+ A P T P ++ P PA +P P L+Q Sbjct: 591 PQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKP----------QLAQKP 640 Query: 91 KQTAASAGLVDAPAPAPAAA 110 Q D P PA AAA Sbjct: 641 SQ--------DVPPPATAAA 652 Score = 32.3 bits (72), Expect = 0.97 Identities = 29/83 (34%), Positives = 35/83 (42%), Gaps = 18/83 (21%) Query: 29 PEPQQPPP----PPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVGSSFFS 84 P P+ PP P P GPG A P A + PPPA+A A P P P + S Sbjct: 609 PVPRTGPPTTQQPRPSGPGPA-GRPKPQLAQKPSQDVPPPATAAAGGP-PHPQLNKS--Q 664 Query: 85 SLSQAVKQTAASAGLVDAPAPAP 107 SL+ A + P PAP Sbjct: 665 SLTNA----------FNLPEPAP 677 Score = 32.0 bits (71), Expect = 1.3 Identities = 15/39 (38%), Positives = 18/39 (46%), Gaps = 1/39 (2%) Query: 38 PPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTP 76 P PG + A P ++RPPP P PQP P P Sbjct: 437 PSPGALPLGRQTSQQPAGPPAQQRPPPQGGP-PQPGPGP 474 Score = 32.0 bits (71), Expect = 1.3 Identities = 26/64 (40%), Positives = 29/64 (45%), Gaps = 19/64 (29%) Query: 27 QRPEPQQPPP---------PPPPGPGAASASAAPPTASPGPERR--PPPA------SAPA 69 Q+P Q PP P GPGA A A P ASP P+R+ PP A S PA Sbjct: 516 QQPASQAAPPTQGQGRQSRPVAGGPGAPPA--ARPPASPSPQRQAGPPQATRQTSVSGPA 573 Query: 70 PQPA 73 P A Sbjct: 574 PPKA 577 >gi|19924097 synapsin I isoform Ib [Homo sapiens] Length = 669 Score = 615 bits (1586), Expect = e-176 Identities = 312/470 (66%), Positives = 367/470 (78%), Gaps = 19/470 (4%) Query: 2 MNFLRRRLSDSSFIANLPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPERR 61 MN+LRRRLSDS+F+ANLPNGYMTDLQRP+P PPPPPG + A+ P TA+ Sbjct: 1 MNYLRRRLSDSNFMANLPNGYMTDLQRPQP----PPPPPGAHSPGATPGPGTATAERSSG 56 Query: 62 PPPASAPAPQPAPTPSVGSSFFSSLSQAVKQTAASAGLV------DAPAPAPAAARKAKV 115 PA++PA P+P S G FFSSLS AVKQT A+A A ++V Sbjct: 57 VAPAASPAA-PSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAASRV 115 Query: 116 LLVVDEPHADWAKCFRGKKVLGDYDIKVEQAEFSELNLVAHADGTYAVDMQVLRNGTKVV 175 LLV+DEPH DWAK F+GKK+ G+ DIKVEQAEFS+LNLVAHA+G ++VDM+VLRNG KVV Sbjct: 116 LLVIDEPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVV 175 Query: 176 RSFRPDFVLIRQHAFGMAENEDFRHLIIGMQYAGLPSINSLESIYNFCDKPWVFAQLVAI 235 RS +PDFVLIRQHAF MA N D+R L+IG+QYAG+PS+NSL S+YNFCDKPWVFAQ+V + Sbjct: 176 RSLKPDFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRL 235 Query: 236 YKTLGGEKFPLIEQTYYPNHKEMLTLPTFPVVVKIGHAHSGMGKVKVENHYDFQDIASVV 295 +K LG E+FPLI+QT+YPNHKEML+ T+PVVVK+GHAHSGMGKVKV+N +DFQDIASVV Sbjct: 236 HKKLGTEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVV 295 Query: 296 ALTQTYATAEPFIDSKYDIRVQKIGNNYKAYMRTSISGNWKTNTGSAMLEQIAMSDRYKL 355 ALT+TYATAEPFID+KYD+RVQKIG NYKAYMRTS+SGNWKTNTGSAMLEQIAMSDRYKL Sbjct: 296 ALTKTYATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKL 355 Query: 356 WVDTCSEMFGGLDICAVKAVHGKDGKDYIFEVMDCSMPLIGEHQVEDRQLITELVISKMN 415 WVDTCSE+FGGLDICAV+A+HGKDG+D+I EV+ SMPLIG+HQ ED+QLI ELV++KM Sbjct: 356 WVDTCSEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMA 415 Query: 416 QLL--SRTPALSPQRPLTTQQPQSGTL----KDPDSSKTPP--QRPPPQG 457 Q L R SP R Q P G L + PP QRPPPQG Sbjct: 416 QALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQG 465 Score = 42.0 bits (97), Expect = 0.001 Identities = 26/66 (39%), Positives = 28/66 (42%), Gaps = 18/66 (27%) Query: 27 QRPEPQQPPPPPPPGPGAAS---------------ASAAPPTASPGPERRPPPASA---P 68 QRP PQ PP P PGP + PP SP P+R P P SA P Sbjct: 459 QRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQP 518 Query: 69 APQPAP 74 A Q AP Sbjct: 519 ASQAAP 524 Score = 41.2 bits (95), Expect = 0.002 Identities = 30/88 (34%), Positives = 39/88 (44%), Gaps = 19/88 (21%) Query: 29 PEPQQPPPPPPPGPGAASASAAPPTASPGPERRP-------PPASAPAPQPAPTPSVGSS 81 P PQ+ P P P ++ AAPPT G + RP PPA+ P P+P G Sbjct: 503 PLPQRL-PSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGP- 560 Query: 82 FFSSLSQAVKQTAASAGLVDAPAPAPAA 109 QA +QT+ V PAP A+ Sbjct: 561 -----PQATRQTS-----VSGPAPPKAS 578 Score = 38.1 bits (87), Expect = 0.018 Identities = 36/115 (31%), Positives = 42/115 (36%), Gaps = 33/115 (28%) Query: 18 LPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPER-------RP-------- 62 LP G T Q P PPP G PP PGP+R RP Sbjct: 442 LPLGRQTSQQPAGPPAQQRPPPQG--------GPPQPGPGPQRQGPPLQQRPPPQGQQHL 493 Query: 63 ----PPASAPAPQPAPTPSVGSSFFSSLSQAVKQTAA----SAGLVDAPAPAPAA 109 PPA +P PQ P+P+ S+ SQA T S + P PAA Sbjct: 494 SGLGPPAGSPLPQRLPSPT--SAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAA 546 Score = 37.0 bits (84), Expect = 0.039 Identities = 26/80 (32%), Positives = 32/80 (40%), Gaps = 18/80 (22%) Query: 31 PQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVGSSFFSSLSQAV 90 PQ+PP P P A+ A P T P ++ P PA +P P L+Q Sbjct: 591 PQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKP----------QLAQKP 640 Query: 91 KQTAASAGLVDAPAPAPAAA 110 Q D P PA AAA Sbjct: 641 SQ--------DVPPPATAAA 652 Score = 32.0 bits (71), Expect = 1.3 Identities = 15/39 (38%), Positives = 18/39 (46%), Gaps = 1/39 (2%) Query: 38 PPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTP 76 P PG + A P ++RPPP P PQP P P Sbjct: 437 PSPGALPLGRQTSQQPAGPPAQQRPPPQGGP-PQPGPGP 474 Score = 32.0 bits (71), Expect = 1.3 Identities = 26/64 (40%), Positives = 29/64 (45%), Gaps = 19/64 (29%) Query: 27 QRPEPQQPPP---------PPPPGPGAASASAAPPTASPGPERR--PPPA------SAPA 69 Q+P Q PP P GPGA A A P ASP P+R+ PP A S PA Sbjct: 516 QQPASQAAPPTQGQGRQSRPVAGGPGAPPA--ARPPASPSPQRQAGPPQATRQTSVSGPA 573 Query: 70 PQPA 73 P A Sbjct: 574 PPKA 577 Score = 31.2 bits (69), Expect = 2.2 Identities = 22/57 (38%), Positives = 27/57 (47%), Gaps = 6/57 (10%) Query: 29 PEPQQPPP----PPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVGSS 81 P P+ PP P P GPG A P A + PPPA+A A P P P + +S Sbjct: 609 PVPRTGPPTTQQPRPSGPGPA-GRPKPQLAQKPSQDVPPPATAAAGGP-PHPQLKAS 663 >gi|209413756 synapsin III isoform IIIg [Homo sapiens] Length = 579 Score = 578 bits (1490), Expect = e-165 Identities = 295/483 (61%), Positives = 360/483 (74%), Gaps = 44/483 (9%) Query: 2 MNFLRRRLSDSSFIANLPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPERR 61 MNFLRRRLSDSSF+ANLPNGYMTDLQRP+ S++++P ASP ERR Sbjct: 1 MNFLRRRLSDSSFMANLPNGYMTDLQRPD---------------SSTSSP--ASPAMERR 43 Query: 62 PPPASAPAPQPAPTPSVGSSFFSSLSQAVKQTA-ASAGLVDAPAPAPAAARKAKVLLVVD 120 P P A S GSS FSSLS A+KQ A++GL++ P P+ ++ ++LLV+D Sbjct: 44 HPQ-----PLAASFSSPGSSLFSSLSSAMKQAPQATSGLMEPPGPSTPIVQRPRILLVID 98 Query: 121 EPHADWAKCFRGKKVLGDYDIKVEQAEFSELNLVAHADGTYAVDMQVLRNGTKVVRSFRP 180 + H DW+K F GKKV G+ +I+VEQAEFSELNL A+ G VDMQV+RNGTKVVRSF+P Sbjct: 99 DAHTDWSKYFHGKKVNGEIEIRVEQAEFSELNLAAYVTGGCMVDMQVVRNGTKVVRSFKP 158 Query: 181 DFVLIRQHAFGMAENEDFRHLIIGMQYAGLPSINSLESIYNFCDKPWVFAQLVAIYKTLG 240 DF+L+RQHA+ MA ED+R L+IG+QY GLP++NSL S+YNFC KPWVF+QL+ I+ +LG Sbjct: 159 DFILVRQHAYSMALGEDYRSLVIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSLG 218 Query: 241 GEKFPLIEQTYYPNHKEMLTLPTFPVVVKIGHAHSGMGKVKVENHYDFQDIASVVALTQT 300 EKFPL+EQT++PNHK M+T P FPVVVK+GHAH+GMGK+KVEN DFQDI SVVA+ +T Sbjct: 219 PEKFPLVEQTFFPNHKPMVTAPHFPVVVKLGHAHAGMGKIKVENQLDFQDITSVVAMAKT 278 Query: 301 YATAEPFIDSKYDIRVQKIGNNYKAYMRTSISGNWKTNTGSAMLEQIAMSDRYKLWVDTC 360 YAT E FIDSKYDIR+QKIG+NYKAYMRTSISGNWK NTGSAMLEQ+AM++RY+LWVD+C Sbjct: 279 YATTEAFIDSKYDIRIQKIGSNYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDSC 338 Query: 361 SEMFGGLDICAVKAVHGKDGKDYIFEVMDCSMPLIGEHQVEDRQLITELVISKMNQLLSR 420 SEMFGGLDICAVKAVH KDG+DYI EVMD SMPLIGEH EDRQL+ +LV+SKM+QL Sbjct: 339 SEMFGGLDICAVKAVHSKDGRDYIIEVMDSSMPLIGEHVEEDRQLMADLVVSKMSQL--P 396 Query: 421 TPALSPQRPLTTQQPQSGTLKDPDSSKTPPQ------RPPPQGCLQYILDCNGIAVGPKQ 474 P + PL PQ + K P ++ PQ RPPPQG GP+Q Sbjct: 397 MPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQG-------------GPRQ 443 Query: 475 VQA 477 Q+ Sbjct: 444 AQS 446 Score = 33.9 bits (76), Expect = 0.33 Identities = 28/86 (32%), Positives = 33/86 (38%), Gaps = 9/86 (10%) Query: 29 PEPQQPPPPPPPGPGAASASAAPP--TASPGPERRPP----PASAPAPQPAPTPSVGSSF 82 P+ QP P PPP G A + P + SP +R P P S + P S GS Sbjct: 426 PQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQ 485 Query: 83 FSSLSQAVKQTAAS---AGLVDAPAP 105 S S AS A L P P Sbjct: 486 LSRASSGSSPNQASKPGATLASQPRP 511 Score = 32.0 bits (71), Expect = 1.3 Identities = 26/78 (33%), Positives = 34/78 (43%), Gaps = 12/78 (15%) Query: 11 DSSFIANLPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPER-----RPPP- 64 D +A+L M+ L P P P P P SA + P A GP+ RPPP Sbjct: 380 DRQLMADLVVSKMSQLPMPGGTAPSPLRPWAPQIKSAKS-PGQAQLGPQLGQPQPRPPPQ 438 Query: 65 -----ASAPAPQPAPTPS 77 A +P PQ + +PS Sbjct: 439 GGPRQAQSPQPQRSGSPS 456 >gi|209413752 synapsin III isoform IIIa [Homo sapiens] Length = 580 Score = 573 bits (1478), Expect = e-164 Identities = 295/484 (60%), Positives = 360/484 (74%), Gaps = 45/484 (9%) Query: 2 MNFLRRRLSDSSFIANLPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPERR 61 MNFLRRRLSDSSF+ANLPNGYMTDLQRP+ S++++P ASP ERR Sbjct: 1 MNFLRRRLSDSSFMANLPNGYMTDLQRPD---------------SSTSSP--ASPAMERR 43 Query: 62 PPPASAPAPQPAPTPSVGSSFFSSLSQAVKQTA-ASAGLVDAPAPAPAAARKAKVLLVVD 120 P P A S GSS FSSLS A+KQ A++GL++ P P+ ++ ++LLV+D Sbjct: 44 HPQ-----PLAASFSSPGSSLFSSLSSAMKQAPQATSGLMEPPGPSTPIVQRPRILLVID 98 Query: 121 EPHADWAKCFRGKKVLGDYDIKVEQAEFSELNLVAHADGTYAVDMQVLRNGTKVV-RSFR 179 + H DW+K F GKKV G+ +I+VEQAEFSELNL A+ G VDMQV+RNGTKVV RSF+ Sbjct: 99 DAHTDWSKYFHGKKVNGEIEIRVEQAEFSELNLAAYVTGGCMVDMQVVRNGTKVVSRSFK 158 Query: 180 PDFVLIRQHAFGMAENEDFRHLIIGMQYAGLPSINSLESIYNFCDKPWVFAQLVAIYKTL 239 PDF+L+RQHA+ MA ED+R L+IG+QY GLP++NSL S+YNFC KPWVF+QL+ I+ +L Sbjct: 159 PDFILVRQHAYSMALGEDYRSLVIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSL 218 Query: 240 GGEKFPLIEQTYYPNHKEMLTLPTFPVVVKIGHAHSGMGKVKVENHYDFQDIASVVALTQ 299 G EKFPL+EQT++PNHK M+T P FPVVVK+GHAH+GMGK+KVEN DFQDI SVVA+ + Sbjct: 219 GPEKFPLVEQTFFPNHKPMVTAPHFPVVVKLGHAHAGMGKIKVENQLDFQDITSVVAMAK 278 Query: 300 TYATAEPFIDSKYDIRVQKIGNNYKAYMRTSISGNWKTNTGSAMLEQIAMSDRYKLWVDT 359 TYAT E FIDSKYDIR+QKIG+NYKAYMRTSISGNWK NTGSAMLEQ+AM++RY+LWVD+ Sbjct: 279 TYATTEAFIDSKYDIRIQKIGSNYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDS 338 Query: 360 CSEMFGGLDICAVKAVHGKDGKDYIFEVMDCSMPLIGEHQVEDRQLITELVISKMNQLLS 419 CSEMFGGLDICAVKAVH KDG+DYI EVMD SMPLIGEH EDRQL+ +LV+SKM+QL Sbjct: 339 CSEMFGGLDICAVKAVHSKDGRDYIIEVMDSSMPLIGEHVEEDRQLMADLVVSKMSQL-- 396 Query: 420 RTPALSPQRPLTTQQPQSGTLKDPDSSKTPPQ------RPPPQGCLQYILDCNGIAVGPK 473 P + PL PQ + K P ++ PQ RPPPQG GP+ Sbjct: 397 PMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQG-------------GPR 443 Query: 474 QVQA 477 Q Q+ Sbjct: 444 QAQS 447 Score = 33.9 bits (76), Expect = 0.33 Identities = 28/86 (32%), Positives = 33/86 (38%), Gaps = 9/86 (10%) Query: 29 PEPQQPPPPPPPGPGAASASAAPP--TASPGPERRPP----PASAPAPQPAPTPSVGSSF 82 P+ QP P PPP G A + P + SP +R P P S + P S GS Sbjct: 427 PQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQ 486 Query: 83 FSSLSQAVKQTAAS---AGLVDAPAP 105 S S AS A L P P Sbjct: 487 LSRASSGSSPNQASKPGATLASQPRP 512 Score = 32.0 bits (71), Expect = 1.3 Identities = 26/78 (33%), Positives = 34/78 (43%), Gaps = 12/78 (15%) Query: 11 DSSFIANLPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPER-----RPPP- 64 D +A+L M+ L P P P P P SA + P A GP+ RPPP Sbjct: 381 DRQLMADLVVSKMSQLPMPGGTAPSPLRPWAPQIKSAKS-PGQAQLGPQLGQPQPRPPPQ 439 Query: 65 -----ASAPAPQPAPTPS 77 A +P PQ + +PS Sbjct: 440 GGPRQAQSPQPQRSGSPS 457 >gi|209413754 synapsin III isoform IIIc [Homo sapiens] Length = 444 Score = 571 bits (1471), Expect = e-163 Identities = 291/466 (62%), Positives = 354/466 (75%), Gaps = 32/466 (6%) Query: 2 MNFLRRRLSDSSFIANLPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPERR 61 MNFLRRRLSDSSF+ANLPNGYMTDLQRP+ S++++P ASP ERR Sbjct: 1 MNFLRRRLSDSSFMANLPNGYMTDLQRPD---------------SSTSSP--ASPAMERR 43 Query: 62 PPPASAPAPQPAPTPSVGSSFFSSLSQAVKQTA-ASAGLVDAPAPAPAAARKAKVLLVVD 120 P P A S GSS FSSLS A+KQ A++GL++ P P+ ++ ++LLV+D Sbjct: 44 HPQ-----PLAASFSSPGSSLFSSLSSAMKQAPQATSGLMEPPGPSTPIVQRPRILLVID 98 Query: 121 EPHADWAKCFRGKKVLGDYDIKVEQAEFSELNLVAHADGTYAVDMQVLRNGTKVV-RSFR 179 + H DW+K F GKKV G+ +I+VEQAEFSELNL A+ G VDMQV+RNGTKVV RSF+ Sbjct: 99 DAHTDWSKYFHGKKVNGEIEIRVEQAEFSELNLAAYVTGGCMVDMQVVRNGTKVVSRSFK 158 Query: 180 PDFVLIRQHAFGMAENEDFRHLIIGMQYAGLPSINSLESIYNFCDKPWVFAQLVAIYKTL 239 PDF+L+RQHA+ MA ED+R L+IG+QY GLP++NSL S+YNFC KPWVF+QL+ I+ +L Sbjct: 159 PDFILVRQHAYSMALGEDYRSLVIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSL 218 Query: 240 GGEKFPLIEQTYYPNHKEMLTLPTFPVVVKIGHAHSGMGKVKVENHYDFQDIASVVALTQ 299 G EKFPL+EQT++PNHK M+T P FPVVVK+GHAH+GMGK+KVEN DFQDI SVVA+ + Sbjct: 219 GPEKFPLVEQTFFPNHKPMVTAPHFPVVVKLGHAHAGMGKIKVENQLDFQDITSVVAMAK 278 Query: 300 TYATAEPFIDSKYDIRVQKIGNNYKAYMRTSISGNWKTNTGSAMLEQIAMSDRYKLWVDT 359 TYAT E FIDSKYDIR+QKIG+NYKAYMRTSISGNWK NTGSAMLEQ+AM++RY+LWVD+ Sbjct: 279 TYATTEAFIDSKYDIRIQKIGSNYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDS 338 Query: 360 CSEMFGGLDICAVKAVHGKDGKDYIFEVMDCSMPLIGEHQVEDRQLITELVISKMNQLLS 419 CSEMFGGLDICAVKAVH KDG+DYI EVMD SMPLIGEH EDRQL+ +LV+SKM+QL Sbjct: 339 CSEMFGGLDICAVKAVHSKDGRDYIIEVMDSSMPLIGEHVEEDRQLMADLVVSKMSQL-- 396 Query: 420 RTPALSPQRPLTTQQPQSGTLKDPDSSKTPPQ------RPPPQGCL 459 P + PL PQ + K P ++ PQ RPPPQ L Sbjct: 397 PMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQANL 442 >gi|110832843 TBP-associated factor 4 [Homo sapiens] Length = 1085 Score = 54.7 bits (130), Expect = 2e-07 Identities = 36/89 (40%), Positives = 39/89 (43%), Gaps = 15/89 (16%) Query: 29 PEPQQPPPPPPPGPGAASASAAPPTASPGPERRPP--PASAPAPQPAPTPSVGSSFFSSL 86 P P P PP P P A +A+ PP +P RPP PA P PA P Sbjct: 250 PAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPP---------- 299 Query: 87 SQAVKQTAASAGLVDAPAPAPAAARKAKV 115 A Q SAG APAPAPAA A V Sbjct: 300 -PAAAQNGGSAGA--APAPAPAAGGPAGV 325 Score = 40.8 bits (94), Expect = 0.003 Identities = 28/100 (28%), Positives = 37/100 (37%), Gaps = 9/100 (9%) Query: 28 RPEPQQPPPPPPPGPGAASASAAPPTASPGPER---------RPPPASAPAPQPAPTPSV 78 RP P+ P P AA+ +A P A GP + R P P P P P P Sbjct: 127 RPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGP 186 Query: 79 GSSFFSSLSQAVKQTAASAGLVDAPAPAPAAARKAKVLLV 118 G +Q + +AA A APA + L+ Sbjct: 187 GKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALL 226 Score = 40.0 bits (92), Expect = 0.005 Identities = 27/83 (32%), Positives = 34/83 (40%), Gaps = 5/83 (6%) Query: 29 PEPQQPPPPPPPGPGAASASAAP-PTASPGPERRPPPASAPAPQPAPTPSVGSSFFSSLS 87 PEP P P GP A +A A P P PGP P P P A T + ++ +S Sbjct: 150 PEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHH 209 Query: 88 QAVKQTA----ASAGLVDAPAPA 106 A + A L+ P PA Sbjct: 210 AAAPAVSLVNNGPAALLPLPKPA 232 Score = 37.7 bits (86), Expect = 0.023 Identities = 26/82 (31%), Positives = 30/82 (36%), Gaps = 14/82 (17%) Query: 36 PPPPPGPGAASASAAPPTASPGPERRPPPASAPAP-----QPAPTPSVGSSFFSSLSQAV 90 P PPP A P P RRP + PAP +P P S GS Sbjct: 87 PEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGS---------C 137 Query: 91 KQTAASAGLVDAPAPAPAAARK 112 A+A + P PAPA K Sbjct: 138 APVPAAAAVAAGPEPAPAGPAK 159 Score = 37.7 bits (86), Expect = 0.023 Identities = 30/95 (31%), Positives = 41/95 (43%), Gaps = 9/95 (9%) Query: 19 PNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGP---ERRPPPASAPAPQPAPT 75 P G+ P PPP G+A A+ AP A+ GP +P P +A A AP Sbjct: 283 PPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAA---APA 339 Query: 76 PSVGSSFFSSLSQAVKQTAASAGLVDAPAPAPAAA 110 P V + S + V+ +A + A PA AA Sbjct: 340 PGVKA---ESPKRVVQAAPPAAQTLAASGPASTAA 371 Score = 35.4 bits (80), Expect = 0.11 Identities = 25/85 (29%), Positives = 34/85 (40%), Gaps = 2/85 (2%) Query: 29 PEPQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVGSSFFSSLSQ 88 P P++P P P P AA PP S G P A+A A P P P+ G + + + Sbjct: 108 PSPRRPLVPAGPAPPAAKLRP-PPEGSAGSCAPVPAAAAVAAGPEPAPA-GPAKPAGPAA 165 Query: 89 AVKQTAASAGLVDAPAPAPAAARKA 113 + G P P P + A Sbjct: 166 LAARAGPGPGPGPGPGPGPGPGKPA 190 Score = 34.7 bits (78), Expect = 0.20 Identities = 22/71 (30%), Positives = 30/71 (42%), Gaps = 8/71 (11%) Query: 40 PGPGAASASAAPPTASPGPER---RPPPASAPAPQPAPTPSVGSSFFSSLSQAVKQTAAS 96 PGPGAA+A+ AP + P+R PPA+ P + S Q + A+ Sbjct: 329 PGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAA 388 Query: 97 AGLVDAPAPAP 107 P PAP Sbjct: 389 -----VPPPAP 394 Score = 31.2 bits (69), Expect = 2.2 Identities = 25/81 (30%), Positives = 30/81 (37%), Gaps = 7/81 (8%) Query: 40 PGPGAASASAAPPTASPGPERRPPPASAPAP------QPA-PTPSVGSSFFSSLSQAVKQ 92 P A + AAP +PG PPPA P +P P+P A K Sbjct: 67 PAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKL 126 Query: 93 TAASAGLVDAPAPAPAAARKA 113 G + AP PAAA A Sbjct: 127 RPPPEGSAGSCAPVPAAAAVA 147 >gi|4826998 splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) [Homo sapiens] Length = 707 Score = 54.3 bits (129), Expect = 2e-07 Identities = 40/109 (36%), Positives = 43/109 (39%), Gaps = 37/109 (33%) Query: 28 RPEPQQPPPPPP-------------PGPGAASA--------------SAAPPTASPGPER 60 +P QQ PPPPP P PG SA S APP + PGP Sbjct: 92 QPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTP 151 Query: 61 RPPPASAPAPQPAPTPSVGSSFFSSLSQAVKQTAASAGLVDAPAPAPAA 109 PPPA AP AP P+ SS V T AG P P PAA Sbjct: 152 TPPPAVTSAPPGAPPPTPPSS-------GVPTTPPQAG---GPPPPPAA 190 Score = 43.5 bits (101), Expect = 4e-04 Identities = 29/84 (34%), Positives = 38/84 (45%), Gaps = 7/84 (8%) Query: 30 EPQQPPPPPPPGPGAASASAAPPTASPGPERRPPP----ASAP--APQPAPTPSVGSSFF 83 + QQ PPP P P PP P +++PPP +S P A P P P VGS+ Sbjct: 67 QQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPP 126 Query: 84 SSLSQAVKQTAASAGLVDAPAPAP 107 +S S A T ++G P P Sbjct: 127 AS-SSAPPATPPTSGAPPGSGPGP 149 Score = 41.6 bits (96), Expect = 0.002 Identities = 19/46 (41%), Positives = 22/46 (47%), Gaps = 3/46 (6%) Query: 34 PPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVG 79 PP PPP P ++ PP A P PPPA+ P P P P G Sbjct: 161 PPGAPPPTPPSSGVPTTPPQAGGPP---PPPAAVPGPGPGPKQGPG 203 Score = 41.2 bits (95), Expect = 0.002 Identities = 21/47 (44%), Positives = 22/47 (46%), Gaps = 1/47 (2%) Query: 34 PPPPPPPGPGAASASAAPPTA-SPGPERRPPPASAPAPQPAPTPSVG 79 P P PPP +A A PPT S G PP A P P PA P G Sbjct: 149 PTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPG 195 Score = 33.9 bits (76), Expect = 0.33 Identities = 24/94 (25%), Positives = 33/94 (35%), Gaps = 7/94 (7%) Query: 21 GYMTDLQRPEP----QQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAP-- 74 G + D + P P Q P PGPG + P P +++ PP P PQ P Sbjct: 26 GGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPH 85 Query: 75 -TPSVGSSFFSSLSQAVKQTAASAGLVDAPAPAP 107 P Q ++ + P PAP Sbjct: 86 QPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAP 119 Score = 32.3 bits (72), Expect = 0.97 Identities = 18/45 (40%), Positives = 18/45 (40%), Gaps = 7/45 (15%) Query: 31 PQQPPPPPPPG-----PGAASASAAPPTASPGPERRPPPASAPAP 70 P PPP PP P A PP A PGP P P P P Sbjct: 162 PGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGP--GPGPKQGPGP 204 Score = 30.0 bits (66), Expect = 4.8 Identities = 17/49 (34%), Positives = 20/49 (40%), Gaps = 8/49 (16%) Query: 31 PQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVG 79 PQ PPPPP AA P PGP++ P P + P G Sbjct: 179 PQAGGPPPPP--------AAVPGPGPGPKQGPGPGGPKGGKMPGGPKPG 219 >gi|153792074 proline rich 12 [Homo sapiens] Length = 2036 Score = 53.5 bits (127), Expect = 4e-07 Identities = 25/49 (51%), Positives = 28/49 (57%), Gaps = 4/49 (8%) Query: 29 PEPQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPA-PTP 76 P+PQ PPPPPPP P S PP +P P PPP P P PA P+P Sbjct: 1467 PQPQPPPPPPPPQPALPS---PPPLVAPTPSSPPPPPLPPPPPPAMPSP 1512 Score = 48.5 bits (114), Expect = 1e-05 Identities = 30/83 (36%), Positives = 33/83 (39%), Gaps = 4/83 (4%) Query: 31 PQQPPPPPPPGPGAASASA----APPTASPGPERRPPPASAPAPQPAPTPSVGSSFFSSL 86 P P PPP PG SA++ PP P PPPA P PQP P P S Sbjct: 1426 PAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSP 1485 Query: 87 SQAVKQTAASAGLVDAPAPAPAA 109 V T +S P P P A Sbjct: 1486 PPLVAPTPSSPPPPPLPPPPPPA 1508 Score = 47.0 bits (110), Expect = 4e-05 Identities = 20/49 (40%), Positives = 24/49 (48%) Query: 28 RPEPQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTP 76 +P+P PPPPP P + AP +SP P PPP P P P P Sbjct: 1468 QPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPP 1516 Score = 40.8 bits (94), Expect = 0.003 Identities = 30/83 (36%), Positives = 34/83 (40%), Gaps = 9/83 (10%) Query: 26 LQRPEPQQPPPPP---PPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVGSSF 82 L P P PPPPP PP P S PP A+ P +AP+P+ P Sbjct: 1488 LVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDT---- 1543 Query: 83 FSSLSQAVKQ-TAASAGLVDAPA 104 L A KQ TAA G D A Sbjct: 1544 -RPLHLAKKQETAAVCGETDEEA 1565 Score = 38.9 bits (89), Expect = 0.010 Identities = 27/98 (27%), Positives = 37/98 (37%), Gaps = 4/98 (4%) Query: 15 IANLPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPE---RRPPPASAPAPQ 71 + LP+ P + PPP P P A + PP P P+ PPP AP P Sbjct: 1436 LPGLPSANSNGTPEPPLLEEKPPPTP-PPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPS 1494 Query: 72 PAPTPSVGSSFFSSLSQAVKQTAASAGLVDAPAPAPAA 109 P P + ++ +A + AP PAA Sbjct: 1495 SPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAA 1532 Score = 34.7 bits (78), Expect = 0.20 Identities = 26/80 (32%), Positives = 33/80 (41%), Gaps = 4/80 (5%) Query: 27 QRPEPQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVGSSFFSSL 86 QRP QPPPPPPP A + + P R A +P P+P G + Sbjct: 293 QRPASAQPPPPPPPA-HALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGP 351 Query: 87 SQAVKQTAASAGLVDAPAPA 106 S A TA ++G P A Sbjct: 352 SGA---TAGASGRATGPEAA 368 Score = 34.3 bits (77), Expect = 0.26 Identities = 31/98 (31%), Positives = 42/98 (42%), Gaps = 13/98 (13%) Query: 39 PPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVGSSFFSSLSQAVKQTAASAG 98 PP P S A P ++ G PP A AP P+P TP +S + +QT +A Sbjct: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKP-ETPEKTTS-----EKPPEQTPETA- 1722 Query: 99 LVDAPAPAPAAARKAKVLLVVDEPHADWAKCFRGKKVL 136 P P A K +L V E + K RG++ L Sbjct: 1723 -----MPEPPAPEKPSLLRPV-EKEKEKEKVTRGERPL 1754 Score = 33.5 bits (75), Expect = 0.44 Identities = 36/122 (29%), Positives = 43/122 (35%), Gaps = 36/122 (29%) Query: 28 RPEPQQPPPPPPPGPG----AASASAAPPTAS----------------PGPERRPP---- 63 RP P PPPPP P AS+SAA A P PER P Sbjct: 228 RPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDT 287 Query: 64 -------PASAPAPQPAPTPSVGSSFFSSLSQAVKQTAASAGLVDAP----APAPAAARK 112 PASA P P P P+ + S + A L +P P+P A Sbjct: 288 VIKHYQRPASA-QPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEP 346 Query: 113 AK 114 +K Sbjct: 347 SK 348 Score = 33.5 bits (75), Expect = 0.44 Identities = 21/70 (30%), Positives = 27/70 (38%), Gaps = 16/70 (22%) Query: 19 PNGYMTDLQRPE-PQQPPPPPP------------PGPGAASASA---APPTASPGPERRP 62 P+G + + P+ P PPPPP P P A+ P T P+ P Sbjct: 778 PHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPP 837 Query: 63 PPASAPAPQP 72 PP P P P Sbjct: 838 PPPPPPPPMP 847 Score = 32.7 bits (73), Expect = 0.74 Identities = 18/44 (40%), Positives = 20/44 (45%), Gaps = 6/44 (13%) Query: 31 PQQPPPPPPPGP------GAASASAAPPTASPGPERRPPPASAP 68 PQ PPPPPPP P A S A+P P RP + P Sbjct: 833 PQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDP 876 Score = 32.3 bits (72), Expect = 0.97 Identities = 22/64 (34%), Positives = 28/64 (43%), Gaps = 5/64 (7%) Query: 31 PQQPPPPPPPGPGAASASAAPPTASPGP----ERRPPPASAPAPQPAPTPSVGSSFFSSL 86 P QPP PPP PG A+ + P G + P P A Q PT S S+ + Sbjct: 479 PPQPPSGPPP-PGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGH 537 Query: 87 SQAV 90 S A+ Sbjct: 538 SPAL 541 Score = 32.3 bits (72), Expect = 0.97 Identities = 14/37 (37%), Positives = 17/37 (45%) Query: 29 PEPQQPPPPPPPGPGAASASAAPPTASPGPERRPPPA 65 P P+ P PPP P + S PP +P PPA Sbjct: 1692 PPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPA 1728 Score = 31.2 bits (69), Expect = 2.2 Identities = 26/90 (28%), Positives = 35/90 (38%), Gaps = 19/90 (21%) Query: 32 QQPPPPPPPGPGAASASAAPPT------ASPGPE-----RRPPPASAP---APQPAPTPS 77 Q+ PPPPPP +A + PT + GP+ PPP P + P+P+PS Sbjct: 761 QKSPPPPPP-----TAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPS 815 Query: 78 VGSSFFSSLSQAVKQTAASAGLVDAPAPAP 107 L A + A P P P Sbjct: 816 ASKVGVHLLEPATRDGAPQPPPPPPPPPPP 845 Score = 31.2 bits (69), Expect = 2.2 Identities = 28/100 (28%), Positives = 35/100 (35%), Gaps = 11/100 (11%) Query: 35 PPPPPPGPGAASAS------AAPPTASPGPERRPPPASAPAPQPAPTPSVGSSFFSSLSQ 88 P PP P +A + P A+P P PPP PAP P + S F S Sbjct: 1012 PNKPPELPSTVNAEPLGLIQSGPHQAAPPPP--PPPPPPPAPASEPKGGLTSPIFCSTKP 1069 Query: 89 AVKQTAASAGLV---DAPAPAPAAARKAKVLLVVDEPHAD 125 +S L+ D P P + DE AD Sbjct: 1070 KKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKAD 1109 Score = 30.0 bits (66), Expect = 4.8 Identities = 16/42 (38%), Positives = 21/42 (50%), Gaps = 1/42 (2%) Query: 426 PQRPLTTQQPQSGTLKDPDSSKTPPQRPPPQGCLQYILDCNG 467 P+R L Q + P S++ PP PPP LQ+ L C G Sbjct: 278 PERALPRQDTVIKHYQRPASAQ-PPPPPPPAHALQHYLSCGG 318 Score = 30.0 bits (66), Expect = 4.8 Identities = 12/20 (60%), Positives = 12/20 (60%) Query: 29 PEPQQPPPPPPPGPGAASAS 48 P PPPPPPP P A AS Sbjct: 1034 PHQAAPPPPPPPPPPPAPAS 1053 Score = 29.6 bits (65), Expect = 6.3 Identities = 26/103 (25%), Positives = 40/103 (38%), Gaps = 10/103 (9%) Query: 20 NGYMT--DLQRPEPQQPPPPPPP-------GPGAASASAAPPTASPGPERRPPPASAPAP 70 NG ++ D+ +P Q P P G G + P +P P R PP P P Sbjct: 180 NGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTP-PYRPGPPDPPPPP 238 Query: 71 QPAPTPSVGSSFFSSLSQAVKQTAASAGLVDAPAPAPAAARKA 113 + PT + S+ + A +Q++ AP P +A Sbjct: 239 RHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERA 281 Score = 29.6 bits (65), Expect = 6.3 Identities = 18/56 (32%), Positives = 21/56 (37%), Gaps = 14/56 (25%) Query: 27 QRPEPQQPPPPPPPGPGA--ASASAAPPTASPGPE------------RRPPPASAP 68 Q P PPPPPPP P + +P S P+ RR PP P Sbjct: 1036 QAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTP 1091 >gi|210031233 PR domain containing 6 [Homo sapiens] Length = 595 Score = 50.8 bits (120), Expect = 3e-06 Identities = 38/99 (38%), Positives = 44/99 (44%), Gaps = 18/99 (18%) Query: 26 LQRPEPQQPPPPPPPGPGAASASAAPPTASPGPER-RPPPASAPAPQPAPTPSVGSSFFS 84 L P+P QPPPPPPP P A P P+ RP PAS + P S S+ + Sbjct: 44 LSAPQPLQPPPPPPP----------PERAEPPPDSLRPRPASLSSASSTPASSSTSASSA 93 Query: 85 SLSQAVKQTAASAGLVDAP-------APAPAAARKAKVL 116 S A AA AGL P AP AAA A+ L Sbjct: 94 SSCAAAAAAAALAGLSALPVSQLPVFAPLAAAAVAAEPL 132 Score = 29.6 bits (65), Expect = 6.3 Identities = 22/76 (28%), Positives = 29/76 (38%) Query: 38 PPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVGSSFFSSLSQAVKQTAASA 97 P G G S A S +PPP P + P P +SLS A A+S+ Sbjct: 28 PHGGAGPLKGSGAAGLLSAPQPLQPPPPPPPPERAEPPPDSLRPRPASLSSASSTPASSS 87 Query: 98 GLVDAPAPAPAAARKA 113 + + AAA A Sbjct: 88 TSASSASSCAAAAAAA 103 >gi|33356148 formin-like 1 [Homo sapiens] Length = 1100 Score = 50.8 bits (120), Expect = 3e-06 Identities = 28/72 (38%), Positives = 32/72 (44%), Gaps = 10/72 (13%) Query: 19 PNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTA---------SPGPERRPP-PASAP 68 P+ + P P PPPPPP PG S APP+A SP P PP P P Sbjct: 526 PSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLP 585 Query: 69 APQPAPTPSVGS 80 P P P P G+ Sbjct: 586 PPPPPPPPPPGT 597 Score = 40.8 bits (94), Expect = 0.003 Identities = 25/65 (38%), Positives = 26/65 (40%), Gaps = 2/65 (3%) Query: 29 PEPQQPPPPP-PPGPGAASASAAPPTASPGPERR-PPPASAPAPQPAPTPSVGSSFFSSL 86 P P P PPP PP PG PP PG + PPP P P P P S L Sbjct: 567 PLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPPDALGRRDSEL 626 Query: 87 SQAVK 91 VK Sbjct: 627 GPGVK 631 Score = 32.7 bits (73), Expect = 0.74 Identities = 22/64 (34%), Positives = 26/64 (40%), Gaps = 2/64 (3%) Query: 11 DSSFIANLPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAP 70 D+ I LP T P P P P A A+ P A+P P PP P+P Sbjct: 497 DAVSIEILPVAVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPP--PPLPGLPSP 554 Query: 71 QPAP 74 Q AP Sbjct: 555 QEAP 558 Score = 32.7 bits (73), Expect = 0.74 Identities = 18/44 (40%), Positives = 18/44 (40%), Gaps = 10/44 (22%) Query: 25 DLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAP 68 DL P P PPPP GP PP P P PPP P Sbjct: 583 DLPPPPPPPPPPPGTDGP-------VPPPPPPPP---PPPGGPP 616 Score = 30.8 bits (68), Expect = 2.8 Identities = 39/144 (27%), Positives = 49/144 (34%), Gaps = 49/144 (34%) Query: 5 LRRRLSDSSFIANLPNGYMTDLQRPEPQQPPPPPPP----------------------GP 42 LR R S+S+ + + PEP++ PP P GP Sbjct: 443 LRERFSESTAMG-------ASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGP 495 Query: 43 GAA-------------SASAAP----PTASPGPERRPPPASAPAPQPAPTPSVGSSFFSS 85 G A S AP PT SP P+ PA+ PAP AP P S Sbjct: 496 GDAVSIEILPVAVATPSGGDAPTPGVPTGSPSPDL--APAAEPAPGAAPPPPPPLPGLPS 553 Query: 86 LSQAVKQTAASA-GLVDAPAPAPA 108 +A A L +P P PA Sbjct: 554 PQEAPPSAPPQAPPLPGSPEPPPA 577 Score = 30.4 bits (67), Expect = 3.7 Identities = 12/19 (63%), Positives = 12/19 (63%) Query: 24 TDLQRPEPQQPPPPPPPGP 42 TD P P PPPPPP GP Sbjct: 597 TDGPVPPPPPPPPPPPGGP 615 Score = 30.0 bits (66), Expect = 4.8 Identities = 12/33 (36%), Positives = 15/33 (45%) Query: 31 PQQPPPPPPPGPGAASASAAPPTASPGPERRPP 63 P PPPPPPPG + PG + + P Sbjct: 603 PPPPPPPPPPGGPPDALGRRDSELGPGVKAKKP 635 Score = 29.3 bits (64), Expect = 8.2 Identities = 23/62 (37%), Positives = 26/62 (41%), Gaps = 14/62 (22%) Query: 29 PEPQQPPPPPPP--GPGAASA-SAAPPT-----ASPGPERRPP--PASAP----APQPAP 74 P P P P P P A A AAPP P P+ PP P AP +P+P P Sbjct: 517 PTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPP 576 Query: 75 TP 76 P Sbjct: 577 AP 578 >gi|226498192 atonal homolog 8 [Homo sapiens] Length = 321 Score = 50.1 bits (118), Expect = 5e-06 Identities = 36/104 (34%), Positives = 45/104 (43%), Gaps = 21/104 (20%) Query: 34 PPPPPPPGPG--AASASAAPPTASPG---------PERRPPPASAPAP--------QPAP 74 PPPPPPP P A A P PG P RP P++ PAP +PAP Sbjct: 124 PPPPPPPAPQSQAPGGPEAQPFREPGLRPRILLCAPPARPAPSAPPAPPAPPESTVRPAP 183 Query: 75 TPSVGSSFFSSLSQAV--KQTAASAGLVDAPAPAPAAARKAKVL 116 G S +SS+S + +SA P A AA+ + K L Sbjct: 184 PTRPGESSYSSISHVIYNNHQDSSASPRKRPGEATAASSEIKAL 227 >gi|38683860 insulin receptor substrate 2 [Homo sapiens] Length = 1338 Score = 50.1 bits (118), Expect = 5e-06 Identities = 38/104 (36%), Positives = 45/104 (43%), Gaps = 11/104 (10%) Query: 19 PNGYMTDLQRPEPQQPPPPPPPGPGAASASAA---PPTASPGPERRPPPASAPAPQPAPT 75 P G + L PE P PP PP P A+ +S+ PP +PG R PPASA A A Sbjct: 998 PVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQPPPPPPAPGELYRLPPASAVA--TAQG 1055 Query: 76 PSVGSSFFSSLSQAVKQTAASAGLVDAP------APAPAAARKA 113 P SS S T + G+ P P P AAR A Sbjct: 1056 PGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPPKPEAARVA 1099 Score = 33.1 bits (74), Expect = 0.57 Identities = 23/91 (25%), Positives = 36/91 (39%), Gaps = 2/91 (2%) Query: 10 SDSSFIANLPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPA 69 SDS + L + D P+ +P P G+ +P +SP P P P+++P+ Sbjct: 967 SDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPS 1026 Query: 70 P--QPAPTPSVGSSFFSSLSQAVKQTAASAG 98 QP P P + + TA G Sbjct: 1027 SSLQPPPPPPAPGELYRLPPASAVATAQGPG 1057 Score = 32.3 bits (72), Expect = 0.97 Identities = 30/96 (31%), Positives = 41/96 (42%), Gaps = 13/96 (13%) Query: 10 SDSSFIANLPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPA 69 SD + + P G + + +R EPQ P P AASA A PT +PP P+ Sbjct: 820 SDQYVLMSSPVGRILEEERLEPQATPGPSQ----AASAFGAGPT-------QPPHPVVPS 868 Query: 70 PQPAPTPSVGSSFFSSLSQAVKQTAAS-AGLVDAPA 104 P P+ F +AV+ T S GL P+ Sbjct: 869 P-VRPSGGRPEGFLGQRGRAVRPTRLSLEGLPSLPS 903 >gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] Length = 538 Score = 50.1 bits (118), Expect = 5e-06 Identities = 30/79 (37%), Positives = 38/79 (48%) Query: 31 PQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVGSSFFSSLSQAV 90 P PP P P AA+A+A PPT +P P P A+APA P + ++ S Sbjct: 108 PPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQP 167 Query: 91 KQTAASAGLVDAPAPAPAA 109 A A + AP PAPAA Sbjct: 168 GPRAQRAAPLAAPPPAPAA 186 Score = 45.4 bits (106), Expect = 1e-04 Identities = 37/101 (36%), Positives = 40/101 (39%), Gaps = 19/101 (18%) Query: 19 PNGYMTDLQRPEPQQPP-PPPPPGPGAASASAAPPTA---------SPGPERRPPPASAP 68 P G P P PPPPP P AA+A A P A SPGP + P A Sbjct: 115 PRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRA 174 Query: 69 APQPAPTPSVGSSFFSSLSQAVKQTAASAGLVDAPAPAPAA 109 AP AP P+ A A AG AP PA AA Sbjct: 175 APLAAPPPA---------PAAPPAVAPPAGPRRAPPPAVAA 206 Score = 40.8 bits (94), Expect = 0.003 Identities = 25/59 (42%), Positives = 26/59 (44%), Gaps = 17/59 (28%) Query: 29 PEPQQPPP---------PPPPGPGAASASAAPPTASP--GPERRPPPASAPAPQPAPTP 76 P P QP P PPP P AAPP +P GP R PPPA A P P P Sbjct: 162 PGPAQPGPRAQRAAPLAAPPPAP------AAPPAVAPPAGPRRAPPPAVAAREPPLPPP 214 Score = 35.0 bits (79), Expect = 0.15 Identities = 21/58 (36%), Positives = 23/58 (39%), Gaps = 6/58 (10%) Query: 29 PEPQQPPPPPPPG-----PGAASASAAPP-TASPGPERRPPPASAPAPQPAPTPSVGS 80 P P PP PP P A A+ PP P P P P PQP P P G+ Sbjct: 182 PAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGA 239 Score = 30.0 bits (66), Expect = 4.8 Identities = 14/25 (56%), Positives = 15/25 (60%), Gaps = 3/25 (12%) Query: 29 PEPQQPPPP---PPPGPGAASASAA 50 P+ QQPPPP PPP GA A A Sbjct: 221 PQQQQPPPPQPQPPPEGGAVRAGGA 245 >gi|56549694 enabled homolog isoform a [Homo sapiens] Length = 591 Score = 49.3 bits (116), Expect = 8e-06 Identities = 25/49 (51%), Positives = 28/49 (57%), Gaps = 6/49 (12%) Query: 31 PQQPPPPP--PPGPGAASASAAPPTASPGPERRPP-PASAPAPQPAPTP 76 P PPPPP PPGP AS + PP PGP PP P++ P P P P P Sbjct: 310 PLAPPPPPPLPPGPAQASVALPPP---PGPPPPPPLPSTGPPPPPPPPP 355 Score = 45.8 bits (107), Expect = 8e-05 Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 3/55 (5%) Query: 34 PPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVGSSFFSSLSQ 88 PP PPPP P ++ PP P P + PPP P P PAP F +S+S+ Sbjct: 333 PPGPPPPPPLPSTGPPPPPPPPPLPNQVPPP---PPPPPAPPLPASGFFLASMSE 384 Score = 31.6 bits (70), Expect = 1.7 Identities = 23/72 (31%), Positives = 30/72 (41%), Gaps = 3/72 (4%) Query: 29 PEPQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVG---SSFFSS 85 P P Q PPPPPP P ++ AS + RP A A A V + F S Sbjct: 355 PLPNQVPPPPPPPPAPPLPASGFFLASMSEDNRPLTGLAAAIAGAKLRKVSRMEDTSFPS 414 Query: 86 LSQAVKQTAASA 97 A+ +AS+ Sbjct: 415 GGNAIGVNSASS 426 >gi|39930375 enabled homolog isoform b [Homo sapiens] Length = 570 Score = 49.3 bits (116), Expect = 8e-06 Identities = 25/49 (51%), Positives = 28/49 (57%), Gaps = 6/49 (12%) Query: 31 PQQPPPPP--PPGPGAASASAAPPTASPGPERRPP-PASAPAPQPAPTP 76 P PPPPP PPGP AS + PP PGP PP P++ P P P P P Sbjct: 310 PLAPPPPPPLPPGPAQASVALPPP---PGPPPPPPLPSTGPPPPPPPPP 355 Score = 45.8 bits (107), Expect = 8e-05 Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 3/55 (5%) Query: 34 PPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVGSSFFSSLSQ 88 PP PPPP P ++ PP P P + PPP P P PAP F +S+S+ Sbjct: 333 PPGPPPPPPLPSTGPPPPPPPPPLPNQVPPP---PPPPPAPPLPASGFFLASMSE 384 Score = 31.6 bits (70), Expect = 1.7 Identities = 23/72 (31%), Positives = 30/72 (41%), Gaps = 3/72 (4%) Query: 29 PEPQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVG---SSFFSS 85 P P Q PPPPPP P ++ AS + RP A A A V + F S Sbjct: 355 PLPNQVPPPPPPPPAPPLPASGFFLASMSEDNRPLTGLAAAIAGAKLRKVSRMEDTSFPS 414 Query: 86 LSQAVKQTAASA 97 A+ +AS+ Sbjct: 415 GGNAIGVNSASS 426 >gi|18079216 CASK interacting protein 1 [Homo sapiens] Length = 1431 Score = 48.9 bits (115), Expect = 1e-05 Identities = 33/90 (36%), Positives = 38/90 (42%), Gaps = 12/90 (13%) Query: 29 PEPQQP-PPPPPPGPGAASASAAPPTASPGPERRPPPASAP----APQPAPTPSVGSSFF 83 P P P PPPPP P A A P+ S GP P PA P A P PS+G+S Sbjct: 1267 PPPVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGAS-- 1324 Query: 84 SSLSQAVKQTAASAGLVDAPAPAPAAARKA 113 K + A + PA P AA A Sbjct: 1325 -----PAKPPSPGAPALHVPAKPPRAAAAA 1349 Score = 47.4 bits (111), Expect = 3e-05 Identities = 31/92 (33%), Positives = 41/92 (44%), Gaps = 12/92 (13%) Query: 31 PQQPPPPPPPGPGAASAS----AAPPTASPGPERRPPPASAPAP--------QPAPTPSV 78 P+ PPPP P P A A +A P+ +P P R+PP A A P PA PS Sbjct: 1272 PKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAKPPSP 1331 Query: 79 GSSFFSSLSQAVKQTAASAGLVDAPAPAPAAA 110 G+ ++ + AA+A AP P A Sbjct: 1332 GAPALHVPAKPPRAAAAAAAAAAAPPAPPEGA 1363 Score = 42.0 bits (97), Expect = 0.001 Identities = 36/121 (29%), Positives = 50/121 (41%), Gaps = 22/121 (18%) Query: 15 IANLPNGYMTDLQRPEPQQPPPP----PPPGPGAASASAAPPTASPGPE----RRPPPAS 66 +A LP+G P P + PP PP P + AS A P + P +PP A+ Sbjct: 1287 VAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAKPPSPGAPALHVPAKPPRAA 1346 Query: 67 APAPQPA---PTPSVGSSFFSSLSQAVKQTAASAGLV-----------DAPAPAPAAARK 112 A A A P P G+S S Q +++T+A DA P +AA K Sbjct: 1347 AAAAAAAAAPPAPPEGASPGDSARQKLEETSACLAAALQAVEEKIRQEDAQGPRDSAAEK 1406 Query: 113 A 113 + Sbjct: 1407 S 1407 Score = 40.0 bits (92), Expect = 0.005 Identities = 23/65 (35%), Positives = 28/65 (43%), Gaps = 6/65 (9%) Query: 20 NGYMTDLQRPE------PQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPA 73 NG T +RP P+ PPPPPP P + PP P E R P +P+P Sbjct: 1172 NGTGTVRRRPASEQAGPPELPPPPPPAEPPPTDLAHLPPLPPPEGEARKPAKPPVSPKPV 1231 Query: 74 PTPSV 78 T V Sbjct: 1232 LTQPV 1236 Score = 38.9 bits (89), Expect = 0.010 Identities = 29/93 (31%), Positives = 38/93 (40%), Gaps = 16/93 (17%) Query: 29 PEPQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAP------------QPAPTP 76 P ++ P P P P A PP SP P PPP +AP P P+P P Sbjct: 1245 PTSKKVPLPGPGSPEVKRAHGTPPPVSPKP---PPPPTAPKPVKAVAGLPSGSAGPSPAP 1301 Query: 77 SVGSSFFSSLSQAVKQTAASAGLVDAPAPAPAA 109 S ++L++ T S G A P+P A Sbjct: 1302 SPARQPPAALAKP-PGTPPSLGASPAKPPSPGA 1333 Score = 38.1 bits (87), Expect = 0.018 Identities = 43/151 (28%), Positives = 55/151 (36%), Gaps = 15/151 (9%) Query: 18 LPNG--YMTDLQRPEPQQPPPPP----PPGPGAASASAAPPTASPGPERRPPPASAPAPQ 71 LP G + T Q P +P P P GP A+A P P+ PP +P+ Sbjct: 767 LPPGTSHFTPPQTPTKTRPGSPQALGGPHGPAPATAKVKPT-----PQLLPPTERPMSPR 821 Query: 72 PAPTPSVGSSFFSSLSQAVKQTAASAGLVDAPAPAPAAARKAKVLLVVDEPHADWAKCFR 131 P F L Q V+ A AP P P A L + E A+ + + Sbjct: 822 SLPQSPTHRGFAYVLPQPVEGEVGPAAPGPAPPPVPTA---VPTLCLPPEADAEPGRPKK 878 Query: 132 GKKVLGDYDIKVEQAEFSELNLVAHADGTYA 162 L Y + E EL LV A G YA Sbjct: 879 RAHSLNRYAASDSEPERDEL-LVPAAAGPYA 908 Score = 35.0 bits (79), Expect = 0.15 Identities = 35/120 (29%), Positives = 40/120 (33%), Gaps = 31/120 (25%) Query: 29 PEPQQPPPPPP---------PGPGAASASAAPPTASPGP---------ERRPPPASAPAP 70 P P P PPP P P + A P SP P + P P S P Sbjct: 1192 PPPPPPAEPPPTDLAHLPPLPPPEGEARKPAKPPVSPKPVLTQPVPKLQGSPTPTSKKVP 1251 Query: 71 QPAP----------TPSVGSSFFSSLSQAVKQTAASAGLVD---APAPAPAAARKAKVLL 117 P P TP S A K A AGL P+PAP+ AR+ L Sbjct: 1252 LPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAAL 1311 Score = 33.5 bits (75), Expect = 0.44 Identities = 28/114 (24%), Positives = 41/114 (35%), Gaps = 18/114 (15%) Query: 26 LQRPEPQ-------QPPPPPPPGPGAASA-----------SAAPPTASPGPERRPPPASA 67 L+R PQ + PPPP P P + S A GP P Sbjct: 618 LRRKAPQSLEVMAIESPPPPEPTPADCQSPKMTTFQDSELSDELQAAMTGPAEVGPTTEK 677 Query: 68 PAPQPAPTPSVGSSFFSSLSQAVKQTAASAGLVDAPAPAPAAARKAKVLLVVDE 121 P+ PTP + SSL + ++S L+ P P++ ++DE Sbjct: 678 PSSHLPPTPRATTRQDSSLGGRARHMSSSQELLGDGPPGPSSPMSRSQEYLLDE 731 Score = 30.8 bits (68), Expect = 2.8 Identities = 17/50 (34%), Positives = 21/50 (42%), Gaps = 6/50 (12%) Query: 30 EPQQPPPPPPP----GPGAASASAAPPTASPGPERRPPPASAPAPQPAPT 75 E + P PPPP G + P + GP PPP P +P PT Sbjct: 1156 EREAGPEPPPPLSVYHNGTGTVRRRPASEQAGPPELPPP--PPPAEPPPT 1203 >gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] Length = 1263 Score = 48.9 bits (115), Expect = 1e-05 Identities = 30/83 (36%), Positives = 33/83 (39%), Gaps = 5/83 (6%) Query: 29 PEPQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVGSSFFSSLSQ 88 P P PPPPPPP PG S+ P PPP S A P P P S S Sbjct: 600 PPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSS 659 Query: 89 AVKQTAASAGLVDAPAPAPAAAR 111 TA + P P P +AR Sbjct: 660 LPGGTA-----IPPPPPLPGSAR 677 Score = 44.7 bits (104), Expect = 2e-04 Identities = 30/79 (37%), Positives = 33/79 (41%), Gaps = 8/79 (10%) Query: 34 PPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVGSSFFSSLSQAVKQT 93 P PP PP PG S + PP +PG PPP P P P P P G SS T Sbjct: 572 PVPPAPPLPGD-SGTIIPPPPAPGDSTTPPPPPPPPPPPPPLP--GGVCISSPPSLPGGT 628 Query: 94 AAS-----AGLVDAPAPAP 107 A S +G P P P Sbjct: 629 AISPPPPLSGDATIPPPPP 647 Score = 43.1 bits (100), Expect = 6e-04 Identities = 24/57 (42%), Positives = 25/57 (43%), Gaps = 6/57 (10%) Query: 29 PEPQQP-----PPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQ-PAPTPSVG 79 P P P PPPPPP PG A PP GP PPP P P P P +G Sbjct: 681 PPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMG 737 Score = 39.3 bits (90), Expect = 0.008 Identities = 24/67 (35%), Positives = 27/67 (40%), Gaps = 6/67 (8%) Query: 16 ANLPNGYMTDLQRPEPQQP--PPPPPPGPGAASASAAPPTASPGPERRPPPASAPA---- 69 ++LP G P P PPPPPP PG+A PP PPP P Sbjct: 658 SSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGI 717 Query: 70 PQPAPTP 76 P P P P Sbjct: 718 PPPPPFP 724 Score = 38.9 bits (89), Expect = 0.010 Identities = 35/98 (35%), Positives = 41/98 (41%), Gaps = 15/98 (15%) Query: 17 NLPNGYMTDLQRPEPQQ------PPPPPPPGPGAASASAAP-PTASPGPERRPPPASAPA 69 +LP G T + P P PPPP P G G S S+ P TA P P P P SA Sbjct: 623 SLPGG--TAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPP--PLPGSARI 678 Query: 70 PQPAPTPSVGSSFFSSLSQAVKQTAASAGLVDAPAPAP 107 P P P P GS + + AG+ P P P Sbjct: 679 P-PPPPPLPGS---AGIPPPPPPLPGEAGMPPPPPPLP 712 Score = 35.0 bits (79), Expect = 0.15 Identities = 20/52 (38%), Positives = 20/52 (38%), Gaps = 8/52 (15%) Query: 31 PQQPPP-------PPPPGPGAASASAAPPTASP-GPERRPPPASAPAPQPAP 74 P PPP PPPP P PP P GP PPP P P P Sbjct: 692 PPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPP 743 Score = 30.4 bits (67), Expect = 3.7 Identities = 21/64 (32%), Positives = 21/64 (32%), Gaps = 13/64 (20%) Query: 29 PEPQQP-----PPPPPPGPGAASASAAPPTAS--------PGPERRPPPASAPAPQPAPT 75 P P P PPPPPP PG PP PG PPP AP Sbjct: 694 PPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPV 753 Query: 76 PSVG 79 G Sbjct: 754 LPFG 757 >gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] Length = 1272 Score = 48.9 bits (115), Expect = 1e-05 Identities = 30/83 (36%), Positives = 33/83 (39%), Gaps = 5/83 (6%) Query: 29 PEPQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVGSSFFSSLSQ 88 P P PPPPPPP PG S+ P PPP S A P P P S S Sbjct: 609 PPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSS 668 Query: 89 AVKQTAASAGLVDAPAPAPAAAR 111 TA + P P P +AR Sbjct: 669 LPGGTA-----IPPPPPLPGSAR 686 Score = 44.7 bits (104), Expect = 2e-04 Identities = 30/79 (37%), Positives = 33/79 (41%), Gaps = 8/79 (10%) Query: 34 PPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVGSSFFSSLSQAVKQT 93 P PP PP PG S + PP +PG PPP P P P P P G SS T Sbjct: 581 PVPPAPPLPGD-SGTIIPPPPAPGDSTTPPPPPPPPPPPPPLP--GGVCISSPPSLPGGT 637 Query: 94 AAS-----AGLVDAPAPAP 107 A S +G P P P Sbjct: 638 AISPPPPLSGDATIPPPPP 656 Score = 43.1 bits (100), Expect = 6e-04 Identities = 24/57 (42%), Positives = 25/57 (43%), Gaps = 6/57 (10%) Query: 29 PEPQQP-----PPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQ-PAPTPSVG 79 P P P PPPPPP PG A PP GP PPP P P P P +G Sbjct: 690 PPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMG 746 Score = 39.3 bits (90), Expect = 0.008 Identities = 24/67 (35%), Positives = 27/67 (40%), Gaps = 6/67 (8%) Query: 16 ANLPNGYMTDLQRPEPQQP--PPPPPPGPGAASASAAPPTASPGPERRPPPASAPA---- 69 ++LP G P P PPPPPP PG+A PP PPP P Sbjct: 667 SSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGI 726 Query: 70 PQPAPTP 76 P P P P Sbjct: 727 PPPPPFP 733 Score = 38.9 bits (89), Expect = 0.010 Identities = 35/98 (35%), Positives = 41/98 (41%), Gaps = 15/98 (15%) Query: 17 NLPNGYMTDLQRPEPQQ------PPPPPPPGPGAASASAAP-PTASPGPERRPPPASAPA 69 +LP G T + P P PPPP P G G S S+ P TA P P P P SA Sbjct: 632 SLPGG--TAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPP--PLPGSARI 687 Query: 70 PQPAPTPSVGSSFFSSLSQAVKQTAASAGLVDAPAPAP 107 P P P P GS + + AG+ P P P Sbjct: 688 P-PPPPPLPGS---AGIPPPPPPLPGEAGMPPPPPPLP 721 Score = 35.0 bits (79), Expect = 0.15 Identities = 20/52 (38%), Positives = 20/52 (38%), Gaps = 8/52 (15%) Query: 31 PQQPPP-------PPPPGPGAASASAAPPTASP-GPERRPPPASAPAPQPAP 74 P PPP PPPP P PP P GP PPP P P P Sbjct: 701 PPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPP 752 Score = 30.4 bits (67), Expect = 3.7 Identities = 21/64 (32%), Positives = 21/64 (32%), Gaps = 13/64 (20%) Query: 29 PEPQQP-----PPPPPPGPGAASASAAPPTAS--------PGPERRPPPASAPAPQPAPT 75 P P P PPPPPP PG PP PG PPP AP Sbjct: 703 PPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPV 762 Query: 76 PSVG 79 G Sbjct: 763 LPFG 766 >gi|145309324 FH2 domain containing 1 [Homo sapiens] Length = 1143 Score = 48.9 bits (115), Expect = 1e-05 Identities = 22/60 (36%), Positives = 27/60 (45%) Query: 15 IANLPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAP 74 IA P + P P PPPPPPP P + + P++ P P P P P P P P Sbjct: 18 IATAPGFMIGQTPPPAPPPPPPPPPPSPPCSCSREECPSSPPPPPPPPLPGEPPIPPPPP 77 Score = 37.7 bits (86), Expect = 0.023 Identities = 21/51 (41%), Positives = 22/51 (43%), Gaps = 7/51 (13%) Query: 29 PEPQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVG 79 P P PPPP PP S S +SP P PPP P P P P G Sbjct: 35 PPPPPPPPPSPP----CSCSREECPSSPPP---PPPPPLPGEPPIPPPPPG 78 Score = 36.6 bits (83), Expect = 0.052 Identities = 17/47 (36%), Positives = 19/47 (40%) Query: 29 PEPQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPT 75 P P PPP PP ++PP P P PP P P PT Sbjct: 36 PPPPPPPPSPPCSCSREECPSSPPPPPPPPLPGEPPIPPPPPGLPPT 82 >gi|14149904 anthrax toxin receptor 1 isoform 1 precursor [Homo sapiens] Length = 564 Score = 48.9 bits (115), Expect = 1e-05 Identities = 27/61 (44%), Positives = 29/61 (47%), Gaps = 2/61 (3%) Query: 18 LPNGYMTDLQRPEPQQPPPPPPPG-PGAASASAAPPTASPGPERRPPPASAPAPQPAPTP 76 L N Y T P P PPPP P P ++ PP SP P PPP AP P AP P Sbjct: 497 LNNAYHTSSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSP-PSTLPPPPQAPPPNRAPPP 555 Query: 77 S 77 S Sbjct: 556 S 556 >gi|11386183 WAS protein family, member 2 [Homo sapiens] Length = 498 Score = 48.1 bits (113), Expect = 2e-05 Identities = 30/97 (30%), Positives = 41/97 (42%), Gaps = 4/97 (4%) Query: 29 PEPQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVGS----SFFS 84 P+ PPPPPPP PP + P PPP P P P P P G+ + Sbjct: 359 PDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPP 418 Query: 85 SLSQAVKQTAASAGLVDAPAPAPAAARKAKVLLVVDE 121 LS K ++ + DA + +A R+ L V+E Sbjct: 419 PLSDTTKPKSSLPAVSDARSDLLSAIRQGFQLRRVEE 455 Score = 39.3 bits (90), Expect = 0.008 Identities = 25/88 (28%), Positives = 30/88 (34%), Gaps = 8/88 (9%) Query: 28 RPEPQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAP--------APQPAPTPSVG 79 +P PP PPPP P PP G PPP S P A P P P Sbjct: 313 KPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPA 372 Query: 80 SSFFSSLSQAVKQTAASAGLVDAPAPAP 107 + + + + Q A P P P Sbjct: 373 ADYPTLPPPPLSQPTGGAPPPPPPPPPP 400 Score = 37.7 bits (86), Expect = 0.023 Identities = 23/65 (35%), Positives = 25/65 (38%), Gaps = 7/65 (10%) Query: 19 PNGYMTDLQRPEPQQPPP------PPPPGPGAASASAAPPTASPGPERRPPPASAPAPQP 72 P G P PPP PPPP P + PP SP P P P A P P Sbjct: 309 PPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSP-PSFPPHPDFAAPPPP 367 Query: 73 APTPS 77 P P+ Sbjct: 368 PPPPA 372 Score = 37.4 bits (85), Expect = 0.030 Identities = 21/52 (40%), Positives = 21/52 (40%), Gaps = 7/52 (13%) Query: 31 PQQPPPPPPPG--PGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVGS 80 P PPP PP G PG A PP P PPP P P P GS Sbjct: 297 PSHPPPAPPLGSPPGPKPGFAPPPAPPP-----PPPPMIGIPPPPPPVGFGS 343 Score = 32.7 bits (73), Expect = 0.74 Identities = 19/52 (36%), Positives = 20/52 (38%), Gaps = 3/52 (5%) Query: 29 PEPQQP---PPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPS 77 P P P PP P PG A PP G PPP +P P PS Sbjct: 300 PPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPS 351 >gi|62000702 diacylglycerol kinase kappa [Homo sapiens] Length = 1271 Score = 48.1 bits (113), Expect = 2e-05 Identities = 29/82 (35%), Positives = 34/82 (41%), Gaps = 5/82 (6%) Query: 27 QRPEPQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVGSSFFSSL 86 + PEP P PPPPP P A ASP P P P AP P P T + ++ Sbjct: 22 ESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELYTEP 81 Query: 87 SQAVKQTAASAGLVDAPAPAPA 108 + AS PAP PA Sbjct: 82 TPEPATEPAS-----EPAPEPA 98 Score = 43.9 bits (102), Expect = 3e-04 Identities = 27/95 (28%), Positives = 38/95 (40%), Gaps = 22/95 (23%) Query: 26 LQRPEPQQPPPPPP-------------PGPGAASASAAPPTASPGPERRPPPASAPAPQP 72 + P P+ P P P P P A+ A+ P P E P PA+ PAP+P Sbjct: 54 IPEPCPELAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEP 113 Query: 73 APTPSVGSSFFSSLSQAVKQTAASAGLVDAPAPAP 107 AP P+ +++ + L P PAP Sbjct: 114 APEPA---------TESAPEPTPEPALESVPEPAP 139 Score = 43.5 bits (101), Expect = 4e-04 Identities = 25/79 (31%), Positives = 33/79 (41%), Gaps = 6/79 (7%) Query: 29 PEPQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVGSSFFSSLSQ 88 PEP P P P A+ A P P PE P PA+ AP+P P P++ S+ + Sbjct: 83 PEPATEPASEP-APEPATEPAPEPATEPAPEPAPEPATESAPEPTPEPAL-----ESVPE 136 Query: 89 AVKQTAASAGLVDAPAPAP 107 + AP P P Sbjct: 137 PAPELTPEVAPELAPEPTP 155 Score = 37.7 bits (86), Expect = 0.023 Identities = 30/94 (31%), Positives = 37/94 (39%), Gaps = 24/94 (25%) Query: 29 PEPQQPPPPPP-------PGPGAASASAAPPTASPGPERRPPPAS------AP--APQPA 73 PEP P P P P P A+ SA PT P E P PA AP AP+P Sbjct: 95 PEPATEPAPEPATEPAPEPAPEPATESAPEPTPEPALESVPEPAPELTPEVAPELAPEPT 154 Query: 74 PTPSVGSSFFSSLSQAVKQTAASAGLVDAPAPAP 107 P P +++ + A P+PAP Sbjct: 155 PEP---------VTELAPEFCPEAAPEFRPSPAP 179 Score = 31.6 bits (70), Expect = 1.7 Identities = 26/86 (30%), Positives = 31/86 (36%), Gaps = 18/86 (20%) Query: 33 QPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQ----------PAPTPSVGSSF 82 Q PP G A + PP P P PPPA PAP P P P + Sbjct: 9 QGTAPPQDGEQPAESPEPPPPWPPPP---PPPAPPPAPPLLSEASPEPIPEPCPELAP-- 63 Query: 83 FSSLSQAVKQTAASAGLVDAPAPAPA 108 +A ++A L P P PA Sbjct: 64 -GPCPEATSESATE--LYTEPTPEPA 86 Score = 31.2 bits (69), Expect = 2.2 Identities = 23/78 (29%), Positives = 29/78 (37%), Gaps = 4/78 (5%) Query: 44 AASASAAPPTASPGPERRP-PPASAPAPQPAPTPSVGSSFFSSLSQAVKQTAASAGLVDA 102 AA+ APP P P PP P P P P P LS+A + A Sbjct: 6 AAAQGTAPPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPL---LSEASPEPIPEPCPELA 62 Query: 103 PAPAPAAARKAKVLLVVD 120 P P P A ++ L + Sbjct: 63 PGPCPEATSESATELYTE 80 Score = 29.3 bits (64), Expect = 8.2 Identities = 26/95 (27%), Positives = 36/95 (37%), Gaps = 32/95 (33%) Query: 29 PEP---QQPPPPPPPGPGAASASAAPPTASP------------GPERRPPPA-------- 65 PEP P P P P A A PT P PE RP PA Sbjct: 127 PEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPV 186 Query: 66 --------SAPAPQPAPTPSVGSSFFSSLSQAVKQ 92 ++P+P P+P+P S +S + + +K+ Sbjct: 187 DTRERGLKTSPSPSPSPSPRTPMS-WSRIKKILKE 220 >gi|62945417 dystrophia myotonica-containing WD repeat motif protein [Homo sapiens] Length = 674 Score = 48.1 bits (113), Expect = 2e-05 Identities = 28/67 (41%), Positives = 33/67 (49%), Gaps = 16/67 (23%) Query: 27 QRPEPQQPPPPPP-----PGPGAASASAAPPTASPGPERRPP-----------PASAPAP 70 Q P P QPP PPP GPGAA +++PP A PGP P P SA A Sbjct: 51 QTPVPPQPPQPPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAG 110 Query: 71 QPAPTPS 77 +P TP+ Sbjct: 111 EPPATPA 117 >gi|90903231 huntingtin [Homo sapiens] Length = 3144 Score = 47.8 bits (112), Expect = 2e-05 Identities = 24/53 (45%), Positives = 29/53 (54%), Gaps = 4/53 (7%) Query: 27 QRPEPQQPPPPPPPGPGAASASAAPPTASP-GPERRPPPASAPAPQPAPTPSV 78 Q+ + QQ PPPPPP P PP A P P+ +PPP P P P P P+V Sbjct: 33 QQQQQQQQPPPPPPPPPPPQLPQPPPQAQPLLPQPQPPP---PPPPPPPGPAV 82 Score = 38.9 bits (89), Expect = 0.010 Identities = 22/54 (40%), Positives = 24/54 (44%), Gaps = 6/54 (11%) Query: 27 QRPEPQQPPPPPP----PGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTP 76 Q+P P PPPPPP P P A P P P PPP A A +P P Sbjct: 39 QQPPPPPPPPPPPQLPQPPPQAQPLLPQPQPPPPPPP--PPPGPAVAEEPLHRP 90 Score = 37.0 bits (84), Expect = 0.039 Identities = 13/20 (65%), Positives = 15/20 (75%) Query: 26 LQRPEPQQPPPPPPPGPGAA 45 L +P+P PPPPPPPGP A Sbjct: 64 LPQPQPPPPPPPPPPGPAVA 83 Score = 31.2 bits (69), Expect = 2.2 Identities = 14/29 (48%), Positives = 14/29 (48%) Query: 31 PQQPPPPPPPGPGAASASAAPPTASPGPE 59 PQ PPPPPP P A A P P E Sbjct: 65 PQPQPPPPPPPPPPGPAVAEEPLHRPKKE 93 >gi|4503519 eukaryotic translation initiation factor 3, subunit 5 epsilon, 47kDa [Homo sapiens] Length = 357 Score = 47.8 bits (112), Expect = 2e-05 Identities = 32/77 (41%), Positives = 37/77 (48%), Gaps = 11/77 (14%) Query: 34 PPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVGSSFFSSLSQAVKQT 93 PP P P P AA AS PT P PA+AP P AP S + ++ + A QT Sbjct: 11 PPATPTPVPAAAPASVPAPT--------PAPAAAPVPAAAPASSSDPAAAAAATAAPGQT 62 Query: 94 AASAGLVDAPAPAPAAA 110 ASA APA PA A Sbjct: 63 PASA---QAPAQTPAPA 76 Score = 41.2 bits (95), Expect = 0.002 Identities = 24/66 (36%), Positives = 36/66 (54%), Gaps = 1/66 (1%) Query: 47 ASAAPPTASPGPERRPPPASAPAPQPAPTPSVGSSFFSSLSQA-VKQTAASAGLVDAPAP 105 A+ A P ++P P PA+APA PAPTP+ ++ + + A AA+A AP Sbjct: 2 ATPAVPVSAPPATPTPVPAAAPASVPAPTPAPAAAPVPAAAPASSSDPAAAAAATAAPGQ 61 Query: 106 APAAAR 111 PA+A+ Sbjct: 62 TPASAQ 67 Score = 38.1 bits (87), Expect = 0.018 Identities = 25/66 (37%), Positives = 29/66 (43%), Gaps = 1/66 (1%) Query: 44 AASASAAPPTASPGPERRPPPASAPAPQPAPTPSVGSSFFSSLSQAVKQTAASA-GLVDA 102 A SA P T +P P P AP P PA P ++ SS A A +A G A Sbjct: 5 AVPVSAPPATPTPVPAAAPASVPAPTPAPAAAPVPAAAPASSSDPAAAAAATAAPGQTPA 64 Query: 103 PAPAPA 108 A APA Sbjct: 65 SAQAPA 70 Score = 35.0 bits (79), Expect = 0.15 Identities = 23/67 (34%), Positives = 29/67 (43%), Gaps = 7/67 (10%) Query: 19 PNGYMTDLQRPEPQQPPPPPP-----PGPGAASASAAPPTASPGPERRP--PPASAPAPQ 71 P T + P P P P P P AA AS++ P A+ P PASA AP Sbjct: 11 PPATPTPVPAAAPASVPAPTPAPAAAPVPAAAPASSSDPAAAAAATAAPGQTPASAQAPA 70 Query: 72 PAPTPSV 78 P P++ Sbjct: 71 QTPAPAL 77 Score = 29.6 bits (65), Expect = 6.3 Identities = 19/64 (29%), Positives = 26/64 (40%), Gaps = 3/64 (4%) Query: 16 ANLPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAP---PTASPGPERRPPPASAPAPQP 72 A++P P P P AA+A+AAP P ++ P + P PA P Sbjct: 24 ASVPAPTPAPAAAPVPAAAPASSSDPAAAAAATAAPGQTPASAQAPAQTPAPALPGPALP 83 Query: 73 APTP 76 P P Sbjct: 84 GPFP 87 >gi|52485606 formin-like 2 [Homo sapiens] Length = 1092 Score = 47.8 bits (112), Expect = 2e-05 Identities = 30/75 (40%), Positives = 33/75 (44%), Gaps = 7/75 (9%) Query: 20 NGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPERRP-PPASAPAPQPAPTPSV 78 NG +T P P PPPPPPP P PP P E P PP + P P P P Sbjct: 545 NGPVTPPMPPPPPPPPPPPPPPP----PPPPPPLPGPAAETVPAPPLAPPLPSAPPLPGT 600 Query: 79 GSS--FFSSLSQAVK 91 S F+S AVK Sbjct: 601 SSPTVVFNSGLAAVK 615 Score = 40.8 bits (94), Expect = 0.003 Identities = 19/49 (38%), Positives = 22/49 (44%), Gaps = 7/49 (14%) Query: 35 PPPPPPGPGAA-------SASAAPPTASPGPERRPPPASAPAPQPAPTP 76 PPPPPP P ++ + PP P P PPP P P P P P Sbjct: 527 PPPPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPLP 575 Score = 40.0 bits (92), Expect = 0.005 Identities = 19/47 (40%), Positives = 19/47 (40%), Gaps = 1/47 (2%) Query: 31 PQQPPPPP-PPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTP 76 P PPPPP PP P P P PPP P P P P P Sbjct: 525 PLPPPPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPPPP 571 Score = 38.9 bits (89), Expect = 0.010 Identities = 18/48 (37%), Positives = 19/48 (39%) Query: 29 PEPQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTP 76 P P PPP PP + P T P PPP P P P P P Sbjct: 525 PLPPPPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPP 572 >gi|110556644 zinc finger protein, multitype 1 [Homo sapiens] Length = 1006 Score = 47.8 bits (112), Expect = 2e-05 Identities = 22/47 (46%), Positives = 25/47 (53%), Gaps = 3/47 (6%) Query: 29 PEPQQPPPPPPPGPGAASASAAPPTASPGPERR---PPPASAPAPQP 72 PEPQ+PPP PPP P AA + PP A P + P PAP P Sbjct: 923 PEPQEPPPGPPPSPAAAPEAVPPPPAPPSYSDKGVQTPSKGTPAPLP 969 Score = 47.0 bits (110), Expect = 4e-05 Identities = 39/114 (34%), Positives = 48/114 (42%), Gaps = 29/114 (25%) Query: 22 YMTDLQRPEPQQPPPPP-PPGPGAASASAAPPTASPGPERR---------------PPPA 65 Y P P++P PP PPGP +A AP A+P RR PPP Sbjct: 705 YCASRHDPPPRRPAAPPGPPGP---AAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPG 761 Query: 66 SAPAPQPAPTPSVGSSFFSSLSQAVKQTAASAGLVDAP---------APAPAAA 110 APAP+ +P P GS L+ A A+ G +D APAPA A Sbjct: 762 HAPAPE-SPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPAPALA 814 Score = 34.7 bits (78), Expect = 0.20 Identities = 17/47 (36%), Positives = 21/47 (44%) Query: 30 EPQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTP 76 EP+ P P PG + S P SP P R S+P P +P P Sbjct: 469 EPEAAPILGPGEPGPQAPSRTPSPRSPAPARVKAELSSPTPGSSPVP 515 Score = 32.3 bits (72), Expect = 0.97 Identities = 25/79 (31%), Positives = 30/79 (37%), Gaps = 6/79 (7%) Query: 31 PQQPPPPPPPGPGAA-SASAAPPTASPGPE-RRPPPASAPAPQPAPTPSVGSSFFSSLSQ 88 P P P P P A+ + P GPE + PPP P+P AP S S Sbjct: 895 PADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPSYSD 954 Query: 89 AVKQTAASAGLVDAPAPAP 107 QT + PAP P Sbjct: 955 KGVQTPSKG----TPAPLP 969 Score = 32.0 bits (71), Expect = 1.3 Identities = 21/69 (30%), Positives = 23/69 (33%), Gaps = 26/69 (37%) Query: 35 PPPPPPGPGAASASAAP--------------------------PTASPGPERRPPPASAP 68 P PPPG A+A P P A PG E R P P Sbjct: 841 PAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGVEARTPADRGP 900 Query: 69 APQPAPTPS 77 +P PAP S Sbjct: 901 SPAPAPAAS 909 Score = 30.8 bits (68), Expect = 2.8 Identities = 15/31 (48%), Positives = 18/31 (58%), Gaps = 2/31 (6%) Query: 48 SAAPPTASPGPERRPP--PASAPAPQPAPTP 76 +A P A PGP R PP PA AP+ +P P Sbjct: 611 AARRPKAPPGPARAPPGQPAEPDAPRSSPGP 641 Score = 29.6 bits (65), Expect = 6.3 Identities = 13/44 (29%), Positives = 18/44 (40%) Query: 32 QQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPT 75 Q+ P P P +A ++ PP P P P+P PT Sbjct: 35 QKATAPEAPSPPSADVNSPPPLPPPTSPGGPKELEGQEPEPRPT 78 >gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo sapiens] Length = 559 Score = 47.4 bits (111), Expect = 3e-05 Identities = 39/144 (27%), Positives = 57/144 (39%), Gaps = 11/144 (7%) Query: 18 LPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPS 77 LP G + L P P PPP PPPG +S A P P P++AP P P Sbjct: 415 LPQGEVQGL--PPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPP 472 Query: 78 VGSSFFSSLSQAVKQTAASAGLVDAPAPAPAAARKAKVLLVVDEPHADWAKCFR------ 131 S S+ + + + DA + A RK L V+E AK R Sbjct: 473 SPPSQVIPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVA 532 Query: 132 ---GKKVLGDYDIKVEQAEFSELN 152 +++ +Y + +EF E++ Sbjct: 533 TILSRRIAVEYSDSEDDSEFDEVD 556 Score = 41.2 bits (95), Expect = 0.002 Identities = 31/90 (34%), Positives = 36/90 (40%), Gaps = 13/90 (14%) Query: 35 PPPPPPGPGAASASAAPPTASPGP---ERRP--------PPASAPAPQPAPTPSVGSSFF 83 PPPPPP GA A P S E RP P +P P P P P + Sbjct: 278 PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337 Query: 84 SSLSQAVKQTAASAGLVDAPAPAPAAARKA 113 SSL ++ T V P P PA A +A Sbjct: 338 SSLRASMTSTPPPP--VPPPPPPPATALQA 365 Score = 38.1 bits (87), Expect = 0.018 Identities = 28/92 (30%), Positives = 34/92 (36%), Gaps = 12/92 (13%) Query: 29 PEPQQPPPPPPPGPGAASASAAPPTASPGPERRPPP-----ASAPAPQPAPTPSVGSSFF 83 P P PPPP P +S A+ + P P PPP APA P P P Sbjct: 322 PTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAP------- 374 Query: 84 SSLSQAVKQTAASAGLVDAPAPAPAAARKAKV 115 ++ V A P+P AR A V Sbjct: 375 LQIAPGVLHPAPPPIAPPLVQPSPPVARAAPV 406 Score = 37.7 bits (86), Expect = 0.023 Identities = 26/82 (31%), Positives = 34/82 (41%), Gaps = 8/82 (9%) Query: 34 PPPPPPPGPGAAS--ASAAPPTASP---GP---ERRPPPASAPAPQPAPTPSVGSSFFSS 85 PP PPPP P A + A A PP +P P PPP + P QP+P + + + Sbjct: 350 PPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCET 409 Query: 86 LSQAVKQTAASAGLVDAPAPAP 107 + GL P P P Sbjct: 410 VPVHPLPQGEVQGLPPPPPPPP 431 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.133 0.402 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 22,592,946 Number of Sequences: 37866 Number of extensions: 1457651 Number of successful extensions: 56838 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 1191 Number of HSP's successfully gapped in prelim test: 1163 Number of HSP's that attempted gapping in prelim test: 19112 Number of HSP's gapped (non-prelim): 21391 length of query: 478 length of database: 18,247,518 effective HSP length: 106 effective length of query: 372 effective length of database: 14,233,722 effective search space: 5294944584 effective search space used: 5294944584 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.