Search of human proteins with 19924099

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19924099 synapsin I isoform Ia [Homo sapiens]
         (705 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19924099 synapsin I isoform Ia [Homo sapiens]                     1446   0.0  
gi|19924097 synapsin I isoform Ib [Homo sapiens]                     1361   0.0  
gi|19924103 synapsin II isoform IIa [Homo sapiens]                    646   0.0  
gi|19924101 synapsin II isoform IIb [Homo sapiens]                    615   e-176
gi|209413756 synapsin III isoform IIIg [Homo sapiens]                 605   e-173
gi|209413752 synapsin III isoform IIIa [Homo sapiens]                 600   e-171
gi|209413754 synapsin III isoform IIIc [Homo sapiens]                 543   e-154
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H...   134   4e-31
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...   133   6e-31
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]    130   4e-30
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho...   115   1e-25
gi|163965366 nascent polypeptide-associated complex alpha subuni...   100   4e-21
gi|150170670 piccolo isoform 2 [Homo sapiens]                          99   1e-20
gi|150378539 piccolo isoform 1 [Homo sapiens]                          99   1e-20
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    96   1e-19
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         96   1e-19
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]               96   1e-19
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    89   1e-17
gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2 pre...    89   1e-17
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    89   1e-17
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    89   1e-17
gi|192807323 SWI/SNF-related matrix-associated actin-dependent r...    88   2e-17
gi|192807320 SWI/SNF-related matrix-associated actin-dependent r...    88   2e-17
gi|192807318 SWI/SNF-related matrix-associated actin-dependent r...    88   2e-17
gi|192807316 SWI/SNF-related matrix-associated actin-dependent r...    88   2e-17
gi|192807314 SWI/SNF-related matrix-associated actin-dependent r...    88   2e-17
gi|192807312 SWI/SNF-related matrix-associated actin-dependent r...    88   2e-17
gi|21071056 SWI/SNF-related matrix-associated actin-dependent re...    88   2e-17
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      88   2e-17
gi|47132519 Ras association and pleckstrin homology domains 1 is...    87   7e-17

>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score = 1446 bits (3743), Expect = 0.0
 Identities = 705/705 (100%), Positives = 705/705 (100%)

Query: 1   MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPA 60
           MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPA
Sbjct: 1   MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPA 60

Query: 61  ASPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAASRVLLVID 120
           ASPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAASRVLLVID
Sbjct: 61  ASPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAASRVLLVID 120

Query: 121 EPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVVRSLKP 180
           EPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVVRSLKP
Sbjct: 121 EPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVVRSLKP 180

Query: 181 DFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKLG 240
           DFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKLG
Sbjct: 181 DFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKLG 240

Query: 241 TEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTKT 300
           TEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTKT
Sbjct: 241 TEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTKT 300

Query: 301 YATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDTC 360
           YATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDTC
Sbjct: 301 YATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDTC 360

Query: 361 SEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMAQALPR 420
           SEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMAQALPR
Sbjct: 361 SEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMAQALPR 420

Query: 421 QRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPP 480
           QRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPP
Sbjct: 421 QRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPP 480

Query: 481 LQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGP 540
           LQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGP
Sbjct: 481 LQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGP 540

Query: 541 GAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGP 600
           GAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGP
Sbjct: 541 GAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGP 600

Query: 601 TRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQL 660
           TRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQL
Sbjct: 601 TRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQL 660

Query: 661 NKSQSLTNAFNLPEPAPPRPSLSQDEVKAETIRSLRKSFASLFSD 705
           NKSQSLTNAFNLPEPAPPRPSLSQDEVKAETIRSLRKSFASLFSD
Sbjct: 661 NKSQSLTNAFNLPEPAPPRPSLSQDEVKAETIRSLRKSFASLFSD 705


>gi|19924097 synapsin I isoform Ib [Homo sapiens]
          Length = 669

 Score = 1361 bits (3522), Expect = 0.0
 Identities = 661/663 (99%), Positives = 661/663 (99%)

Query: 1   MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPA 60
           MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPA
Sbjct: 1   MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPA 60

Query: 61  ASPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAASRVLLVID 120
           ASPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAASRVLLVID
Sbjct: 61  ASPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAASRVLLVID 120

Query: 121 EPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVVRSLKP 180
           EPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVVRSLKP
Sbjct: 121 EPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVVRSLKP 180

Query: 181 DFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKLG 240
           DFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKLG
Sbjct: 181 DFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKLG 240

Query: 241 TEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTKT 300
           TEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTKT
Sbjct: 241 TEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTKT 300

Query: 301 YATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDTC 360
           YATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDTC
Sbjct: 301 YATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDTC 360

Query: 361 SEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMAQALPR 420
           SEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMAQALPR
Sbjct: 361 SEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMAQALPR 420

Query: 421 QRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPP 480
           QRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPP
Sbjct: 421 QRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPP 480

Query: 481 LQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGP 540
           LQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGP
Sbjct: 481 LQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGP 540

Query: 541 GAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGP 600
           GAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGP
Sbjct: 541 GAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGP 600

Query: 601 TRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQL 660
           TRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQL
Sbjct: 601 TRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQL 660

Query: 661 NKS 663
             S
Sbjct: 661 KAS 663



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 41/124 (33%), Positives = 53/124 (42%), Gaps = 21/124 (16%)

Query: 555 QRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTG 614
           QR A P + +   +   P+P    GA P G+Q     Q+P GP    R   Q GP P+ G
Sbjct: 423 QRDASPGRGSHGQT---PSP----GALPLGRQTS---QQPAGPPAQQRPPPQGGP-PQPG 471

Query: 615 PPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLNKSQSLTNAFNLPE 674
           P     P+  GP    RP PQ  Q+    + PPA     G P PQ   S +        +
Sbjct: 472 PG----PQRQGPPLQQRPPPQ-GQQHLSGLGPPA-----GSPLPQRLPSPTSAPQQPASQ 521

Query: 675 PAPP 678
            APP
Sbjct: 522 AAPP 525


>gi|19924103 synapsin II isoform IIa [Homo sapiens]
          Length = 582

 Score =  646 bits (1667), Expect = 0.0
 Identities = 345/568 (60%), Positives = 405/568 (71%), Gaps = 32/568 (5%)

Query: 1   MNYLRRRLSDSNFMANLPNGYMTDLQRPQP----PPPPPGAHSPGATPGPGTATAERSSG 56
           MN+LRRRLSDS+F+ANLPNGYMTDLQRP+P    PPPPPG  +  A+  P TA+      
Sbjct: 2   MNFLRRRLSDSSFIANLPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPERR 61

Query: 57  VAPAASPAA-PSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAASRV 115
             PA++PA  P+P  S G  FFSSLS AVKQT A+A              A      ++V
Sbjct: 62  PPPASAPAPQPAPTPSVGSSFFSSLSQAVKQTAASAGLV------DAPAPAPAAARKAKV 115

Query: 116 LLVIDEPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVV 175
           LLV+DEPH DWAK F+GKK+ G+ DIKVEQAEFS+LNLVAHA+G ++VDM+VLRNG KVV
Sbjct: 116 LLVVDEPHADWAKCFRGKKVLGDYDIKVEQAEFSELNLVAHADGTYAVDMQVLRNGTKVV 175

Query: 176 RSLKPDFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRL 235
           RS +PDFVLIRQHAF MA N D+R L+IG+QYAG+PS+NSL S+YNFCDKPWVFAQ+V +
Sbjct: 176 RSFRPDFVLIRQHAFGMAENEDFRHLIIGMQYAGLPSINSLESIYNFCDKPWVFAQLVAI 235

Query: 236 HKKLGTEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVV 295
           +K LG E+FPLI+QT+YPNHKEML+  T+PVVVK+GHAHSGMGKVKV+N +DFQDIASVV
Sbjct: 236 YKTLGGEKFPLIEQTYYPNHKEMLTLPTFPVVVKIGHAHSGMGKVKVENHYDFQDIASVV 295

Query: 296 ALTKTYATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKL 355
           ALT+TYATAEPFID+KYD+RVQKIG NYKAYMRTS+SGNWKTNTGSAMLEQIAMSDRYKL
Sbjct: 296 ALTQTYATAEPFIDSKYDIRVQKIGNNYKAYMRTSISGNWKTNTGSAMLEQIAMSDRYKL 355

Query: 356 WVDTCSEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMA 415
           WVDTCSE+FGGLDICAV+A+HGKDG+D+I EV+  SMPLIG+HQ ED+QLI ELV++KM 
Sbjct: 356 WVDTCSEMFGGLDICAVKAVHGKDGKDYIFEVMDCSMPLIGEHQVEDRQLITELVISKMN 415

Query: 416 QALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQ 475
           Q L   R    SP R    Q P  G L    +       PP  QRPPPQGGP QP  G Q
Sbjct: 416 QLL--SRTPALSPQRPLTTQQPQSGTL----KDPDSSKTPP--QRPPPQGGPGQP-QGMQ 466

Query: 476 RQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRP 535
             G  L  R  P G        PP+ S       S +SAPQ+P     P T G    S  
Sbjct: 467 PPGKVLPPRRLPPGPSL-----PPSSS---SSSSSSSSAPQRP---GGPTTHGDAPSSSS 515

Query: 536 VAGGPGAPPAARPPASPSPQRQAGPPQA 563
            +     PP A PP  P P  Q    Q+
Sbjct: 516 -SLAEAQPPLAAPPQKPQPHPQLNKSQS 542



 Score =  103 bits (258), Expect = 4e-22
 Identities = 79/206 (38%), Positives = 90/206 (43%), Gaps = 54/206 (26%)

Query: 505 PQRLPSPTSAPQQ-----PASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAG 559
           PQR P  T  PQ      P S   PP      Q  P  GGPG P   +PP    P R+  
Sbjct: 426 PQR-PLTTQQPQSGTLKDPDSSKTPP------QRPPPQGGPGQPQGMQPPGKVLPPRR-- 476

Query: 560 PPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQ 619
                                PPG       P  PP  +  +  +S A    R G PTT 
Sbjct: 477 --------------------LPPG-------PSLPPSSSSSSSSSSSA--PQRPGGPTTH 507

Query: 620 QPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLNKSQSLTNAFNLPEPAPPR 679
              PS        +P LA  P +             PHPQLNKSQSLTNAF+  E +  R
Sbjct: 508 GDAPSSSSSLAEAQPPLAAPPQKP-----------QPHPQLNKSQSLTNAFSFSESSFFR 556

Query: 680 PSLSQDEVKAETIRSLRKSFASLFSD 705
            S ++DE KAETIRSLRKSFASLFSD
Sbjct: 557 SSANEDEAKAETIRSLRKSFASLFSD 582



 Score = 37.0 bits (84), Expect = 0.063
 Identities = 26/80 (32%), Positives = 32/80 (40%), Gaps = 18/80 (22%)

Query: 591 PQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKP----------QLAQKP 640
           PQ+PP P  P   A+ A   P T  P  ++  P    PA +P P           L+Q  
Sbjct: 31  PQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVGSSFFSSLSQAV 90

Query: 641 SQ--------DVPPPATAAA 652
            Q        D P PA AAA
Sbjct: 91  KQTAASAGLVDAPAPAPAAA 110



 Score = 33.1 bits (74), Expect = 0.91
 Identities = 24/65 (36%), Positives = 28/65 (43%), Gaps = 13/65 (20%)

Query: 516 QQPASQAAPPTQGQGRQSRPVAGGPGAPP--AARPPASPSPQRQAGPPQATRQTSVSGPA 573
           Q+P  Q  PP         P   GPGA    AA P ASP P+R+  PP A+       P 
Sbjct: 27  QRPEPQQPPP---------PPPPGPGAASASAAPPTASPGPERR--PPPASAPAPQPAPT 75

Query: 574 PPKAS 578
           P   S
Sbjct: 76  PSVGS 80



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 29/83 (34%), Positives = 35/83 (42%), Gaps = 18/83 (21%)

Query: 609 PVPRTGPPTTQQPRPSGPGPA-GRPKPQLAQKPSQDVPPPATAAAGGP-PHPQLNKS--Q 664
           P P+  PP    P P GPG A     P  A    +  PPPA+A A  P P P +  S   
Sbjct: 29  PEPQQPPP----PPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVGSSFFS 84

Query: 665 SLTNA----------FNLPEPAP 677
           SL+ A           + P PAP
Sbjct: 85  SLSQAVKQTAASAGLVDAPAPAP 107


>gi|19924101 synapsin II isoform IIb [Homo sapiens]
          Length = 478

 Score =  615 bits (1586), Expect = e-176
 Identities = 312/470 (66%), Positives = 367/470 (78%), Gaps = 19/470 (4%)

Query: 1   MNYLRRRLSDSNFMANLPNGYMTDLQRPQP----PPPPPGAHSPGATPGPGTATAERSSG 56
           MN+LRRRLSDS+F+ANLPNGYMTDLQRP+P    PPPPPG  +  A+  P TA+      
Sbjct: 2   MNFLRRRLSDSSFIANLPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPERR 61

Query: 57  VAPAASPAA-PSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAASRV 115
             PA++PA  P+P  S G  FFSSLS AVKQT A+A              A      ++V
Sbjct: 62  PPPASAPAPQPAPTPSVGSSFFSSLSQAVKQTAASAGLV------DAPAPAPAAARKAKV 115

Query: 116 LLVIDEPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVV 175
           LLV+DEPH DWAK F+GKK+ G+ DIKVEQAEFS+LNLVAHA+G ++VDM+VLRNG KVV
Sbjct: 116 LLVVDEPHADWAKCFRGKKVLGDYDIKVEQAEFSELNLVAHADGTYAVDMQVLRNGTKVV 175

Query: 176 RSLKPDFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRL 235
           RS +PDFVLIRQHAF MA N D+R L+IG+QYAG+PS+NSL S+YNFCDKPWVFAQ+V +
Sbjct: 176 RSFRPDFVLIRQHAFGMAENEDFRHLIIGMQYAGLPSINSLESIYNFCDKPWVFAQLVAI 235

Query: 236 HKKLGTEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVV 295
           +K LG E+FPLI+QT+YPNHKEML+  T+PVVVK+GHAHSGMGKVKV+N +DFQDIASVV
Sbjct: 236 YKTLGGEKFPLIEQTYYPNHKEMLTLPTFPVVVKIGHAHSGMGKVKVENHYDFQDIASVV 295

Query: 296 ALTKTYATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKL 355
           ALT+TYATAEPFID+KYD+RVQKIG NYKAYMRTS+SGNWKTNTGSAMLEQIAMSDRYKL
Sbjct: 296 ALTQTYATAEPFIDSKYDIRVQKIGNNYKAYMRTSISGNWKTNTGSAMLEQIAMSDRYKL 355

Query: 356 WVDTCSEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMA 415
           WVDTCSE+FGGLDICAV+A+HGKDG+D+I EV+  SMPLIG+HQ ED+QLI ELV++KM 
Sbjct: 356 WVDTCSEMFGGLDICAVKAVHGKDGKDYIFEVMDCSMPLIGEHQVEDRQLITELVISKMN 415

Query: 416 QALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQG 465
           Q L   R    SP R    Q P  G L    +       PP  QRPPPQG
Sbjct: 416 QLL--SRTPALSPQRPLTTQQPQSGTL----KDPDSSKTPP--QRPPPQG 457



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 26/66 (39%), Positives = 28/66 (42%), Gaps = 18/66 (27%)

Query: 459 QRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQP 518
           QRP PQ  PP P PGP                   +   PP  SP P+R P P SA   P
Sbjct: 27  QRPEPQQPPPPPPPGPGAAS---------------ASAAPPTASPGPERRPPPASA---P 68

Query: 519 ASQAAP 524
           A Q AP
Sbjct: 69  APQPAP 74



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 30/88 (34%), Positives = 39/88 (44%), Gaps = 19/88 (21%)

Query: 503 PLPQRLPSPTS-APQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGP- 560
           P PQ+ P P    P   ++ AAPPT   G + RP       PPA+ P   P+P    G  
Sbjct: 29  PEPQQPPPPPPPGPGAASASAAPPTASPGPERRP-------PPASAPAPQPAPTPSVGSS 81

Query: 561 -----PQATRQTS-----VSGPAPPKAS 578
                 QA +QT+     V  PAP  A+
Sbjct: 82  FFSSLSQAVKQTAASAGLVDAPAPAPAA 109



 Score = 38.1 bits (87), Expect = 0.028
 Identities = 36/115 (31%), Positives = 42/115 (36%), Gaps = 33/115 (28%)

Query: 442 LPLGRQTSQQPAGPPAQQRPPPQG--------GPPQPGPGPQRQGPPLQQRPPPQGQQHL 493
           LP G  T  Q   P     PPP G         PP   PGP+R       RP        
Sbjct: 18  LPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPER-------RP-------- 62

Query: 494 SGLGPPAGSPLPQRLPSPT--SAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAA 546
               PPA +P PQ  P+P+  S+     SQA   T      S  +   P   PAA
Sbjct: 63  ----PPASAPAPQPAPTPSVGSSFFSSLSQAVKQTAA----SAGLVDAPAPAPAA 109



 Score = 37.0 bits (84), Expect = 0.063
 Identities = 26/80 (32%), Positives = 32/80 (40%), Gaps = 18/80 (22%)

Query: 591 PQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKP----------QLAQKP 640
           PQ+PP P  P   A+ A   P T  P  ++  P    PA +P P           L+Q  
Sbjct: 31  PQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVGSSFFSSLSQAV 90

Query: 641 SQ--------DVPPPATAAA 652
            Q        D P PA AAA
Sbjct: 91  KQTAASAGLVDAPAPAPAAA 110



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 29/83 (34%), Positives = 35/83 (42%), Gaps = 18/83 (21%)

Query: 609 PVPRTGPPTTQQPRPSGPGPA-GRPKPQLAQKPSQDVPPPATAAAGGP-PHPQLNKS--Q 664
           P P+  PP    P P GPG A     P  A    +  PPPA+A A  P P P +  S   
Sbjct: 29  PEPQQPPP----PPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVGSSFFS 84

Query: 665 SLTNA----------FNLPEPAP 677
           SL+ A           + P PAP
Sbjct: 85  SLSQAVKQTAASAGLVDAPAPAP 107



 Score = 32.0 bits (71), Expect = 2.0
 Identities = 26/64 (40%), Positives = 29/64 (45%), Gaps = 19/64 (29%)

Query: 516 QQPASQAAPPTQGQGRQSRPVAGGPGAPPA--ARPPASPSPQRQAGPPQATRQTSVSGPA 573
           Q+P  Q  PP         P   GPGA  A  A P ASP P+R+  PP A      S PA
Sbjct: 27  QRPEPQQPPP---------PPPPGPGAASASAAPPTASPGPERR--PPPA------SAPA 69

Query: 574 PPKA 577
           P  A
Sbjct: 70  PQPA 73



 Score = 32.0 bits (71), Expect = 2.0
 Identities = 15/39 (38%), Positives = 18/39 (46%), Gaps = 1/39 (2%)

Query: 437 PSPGALPLGRQTSQQPAGPPAQQRPPPQGGP-PQPGPGP 474
           P PG        +   A P  ++RPPP   P PQP P P
Sbjct: 38  PPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTP 76


>gi|209413756 synapsin III isoform IIIg [Homo sapiens]
          Length = 579

 Score =  605 bits (1560), Expect = e-173
 Identities = 342/705 (48%), Positives = 430/705 (60%), Gaps = 126/705 (17%)

Query: 1   MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPA 60
           MN+LRRRLSDS+FMANLPNGYMTDLQRP             +T  P +   ER      A
Sbjct: 1   MNFLRRRLSDSSFMANLPNGYMTDLQRPD-----------SSTSSPASPAMERRHPQPLA 49

Query: 61  ASPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAASRVLLVID 120
           AS ++P      G   FSSLS+A+KQ   A +    E  G  +    R     R+LLVID
Sbjct: 50  ASFSSP------GSSLFSSLSSAMKQAPQATSGLM-EPPGPSTPIVQR----PRILLVID 98

Query: 121 EPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVVRSLKP 180
           + HTDW+KYF GKK++GEI+I+VEQAEFS+LNL A+  GG  VDM+V+RNG KVVRS KP
Sbjct: 99  DAHTDWSKYFHGKKVNGEIEIRVEQAEFSELNLAAYVTGGCMVDMQVVRNGTKVVRSFKP 158

Query: 181 DFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKLG 240
           DF+L+RQHA+SMA   DYRSLVIGLQY G+P+VNSL+SVYNFC KPWVF+Q++++   LG
Sbjct: 159 DFILVRQHAYSMALGEDYRSLVIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSLG 218

Query: 241 TEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTKT 300
            E+FPL++QTF+PNHK M+++  +PVVVK+GHAH+GMGK+KV+NQ DFQDI SVVA+ KT
Sbjct: 219 PEKFPLVEQTFFPNHKPMVTAPHFPVVVKLGHAHAGMGKIKVENQLDFQDITSVVAMAKT 278

Query: 301 YATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDTC 360
           YAT E FID+KYD+R+QKIG NYKAYMRTS+SGNWK NTGSAMLEQ+AM++RY+LWVD+C
Sbjct: 279 YATTEAFIDSKYDIRIQKIGSNYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDSC 338

Query: 361 SEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMAQALPR 420
           SE+FGGLDICAV+A+H KDGRD+IIEV+ SSMPLIG+H +ED+QL+ +LVV+KM+     
Sbjct: 339 SEMFGGLDICAVKAVHSKDGRDYIIEVMDSSMPLIGEHVEEDRQLMADLVVSKMS----- 393

Query: 421 QRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPP 480
                         Q P PG                               P P R   P
Sbjct: 394 --------------QLPMPGGT----------------------------APSPLRPWAP 411

Query: 481 LQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGP 540
             +     GQ  L   GP  G P P+                 PP QG  RQ++      
Sbjct: 412 QIKSAKSPGQAQL---GPQLGQPQPR-----------------PPPQGGPRQAQ------ 445

Query: 541 GAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGP 600
                     SP PQR   P Q  ++ S  G  P       P  Q+  G PQ     +G 
Sbjct: 446 ----------SPQPQRSGSPSQ--QRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSG- 492

Query: 601 TRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQL 660
               S      + G     QPRP   G +   + + ++KP+             PPHP L
Sbjct: 493 ----SSPNQASKPGATLASQPRPPVQGRSTSQQGEESKKPA-------------PPHPHL 535

Query: 661 NKSQSLTNAFNLPEPAPPRPSLSQDEVKAETIRSLRKSFASLFSD 705
           NKSQSLTN+ +  + +  R + S+DE KAETIR+LRKSFASLFSD
Sbjct: 536 NKSQSLTNSLSTSDTSQ-RGTPSEDEAKAETIRNLRKSFASLFSD 579


>gi|209413752 synapsin III isoform IIIa [Homo sapiens]
          Length = 580

 Score =  600 bits (1548), Expect = e-171
 Identities = 342/706 (48%), Positives = 430/706 (60%), Gaps = 127/706 (17%)

Query: 1   MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPA 60
           MN+LRRRLSDS+FMANLPNGYMTDLQRP             +T  P +   ER      A
Sbjct: 1   MNFLRRRLSDSSFMANLPNGYMTDLQRPD-----------SSTSSPASPAMERRHPQPLA 49

Query: 61  ASPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAASRVLLVID 120
           AS ++P      G   FSSLS+A+KQ   A +    E  G  +    R     R+LLVID
Sbjct: 50  ASFSSP------GSSLFSSLSSAMKQAPQATSGLM-EPPGPSTPIVQR----PRILLVID 98

Query: 121 EPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVV-RSLK 179
           + HTDW+KYF GKK++GEI+I+VEQAEFS+LNL A+  GG  VDM+V+RNG KVV RS K
Sbjct: 99  DAHTDWSKYFHGKKVNGEIEIRVEQAEFSELNLAAYVTGGCMVDMQVVRNGTKVVSRSFK 158

Query: 180 PDFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKL 239
           PDF+L+RQHA+SMA   DYRSLVIGLQY G+P+VNSL+SVYNFC KPWVF+Q++++   L
Sbjct: 159 PDFILVRQHAYSMALGEDYRSLVIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSL 218

Query: 240 GTEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTK 299
           G E+FPL++QTF+PNHK M+++  +PVVVK+GHAH+GMGK+KV+NQ DFQDI SVVA+ K
Sbjct: 219 GPEKFPLVEQTFFPNHKPMVTAPHFPVVVKLGHAHAGMGKIKVENQLDFQDITSVVAMAK 278

Query: 300 TYATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDT 359
           TYAT E FID+KYD+R+QKIG NYKAYMRTS+SGNWK NTGSAMLEQ+AM++RY+LWVD+
Sbjct: 279 TYATTEAFIDSKYDIRIQKIGSNYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDS 338

Query: 360 CSEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMAQALP 419
           CSE+FGGLDICAV+A+H KDGRD+IIEV+ SSMPLIG+H +ED+QL+ +LVV+KM+    
Sbjct: 339 CSEMFGGLDICAVKAVHSKDGRDYIIEVMDSSMPLIGEHVEEDRQLMADLVVSKMS---- 394

Query: 420 RQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGP 479
                          Q P PG                               P P R   
Sbjct: 395 ---------------QLPMPGGT----------------------------APSPLRPWA 411

Query: 480 PLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGG 539
           P  +     GQ  L   GP  G P P+                 PP QG  RQ++     
Sbjct: 412 PQIKSAKSPGQAQL---GPQLGQPQPR-----------------PPPQGGPRQAQ----- 446

Query: 540 PGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAG 599
                      SP PQR   P Q  ++ S  G  P       P  Q+  G PQ     +G
Sbjct: 447 -----------SPQPQRSGSPSQ--QRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSG 493

Query: 600 PTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQ 659
                S      + G     QPRP   G +   + + ++KP+             PPHP 
Sbjct: 494 -----SSPNQASKPGATLASQPRPPVQGRSTSQQGEESKKPA-------------PPHPH 535

Query: 660 LNKSQSLTNAFNLPEPAPPRPSLSQDEVKAETIRSLRKSFASLFSD 705
           LNKSQSLTN+ +  + +  R + S+DE KAETIR+LRKSFASLFSD
Sbjct: 536 LNKSQSLTNSLSTSDTSQ-RGTPSEDEAKAETIRNLRKSFASLFSD 580


>gi|209413754 synapsin III isoform IIIc [Homo sapiens]
          Length = 444

 Score =  543 bits (1400), Expect = e-154
 Identities = 285/481 (59%), Positives = 353/481 (73%), Gaps = 38/481 (7%)

Query: 1   MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPA 60
           MN+LRRRLSDS+FMANLPNGYMTDLQRP             +T  P +   ER      A
Sbjct: 1   MNFLRRRLSDSSFMANLPNGYMTDLQRPD-----------SSTSSPASPAMERRHPQPLA 49

Query: 61  ASPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAASRVLLVID 120
           AS ++P      G   FSSLS+A+KQ   A +    E  G  +    R     R+LLVID
Sbjct: 50  ASFSSP------GSSLFSSLSSAMKQAPQATSGLM-EPPGPSTPIVQR----PRILLVID 98

Query: 121 EPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVV-RSLK 179
           + HTDW+KYF GKK++GEI+I+VEQAEFS+LNL A+  GG  VDM+V+RNG KVV RS K
Sbjct: 99  DAHTDWSKYFHGKKVNGEIEIRVEQAEFSELNLAAYVTGGCMVDMQVVRNGTKVVSRSFK 158

Query: 180 PDFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKL 239
           PDF+L+RQHA+SMA   DYRSLVIGLQY G+P+VNSL+SVYNFC KPWVF+Q++++   L
Sbjct: 159 PDFILVRQHAYSMALGEDYRSLVIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSL 218

Query: 240 GTEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTK 299
           G E+FPL++QTF+PNHK M+++  +PVVVK+GHAH+GMGK+KV+NQ DFQDI SVVA+ K
Sbjct: 219 GPEKFPLVEQTFFPNHKPMVTAPHFPVVVKLGHAHAGMGKIKVENQLDFQDITSVVAMAK 278

Query: 300 TYATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDT 359
           TYAT E FID+KYD+R+QKIG NYKAYMRTS+SGNWK NTGSAMLEQ+AM++RY+LWVD+
Sbjct: 279 TYATTEAFIDSKYDIRIQKIGSNYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDS 338

Query: 360 CSEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMAQALP 419
           CSE+FGGLDICAV+A+H KDGRD+IIEV+ SSMPLIG+H +ED+QL+ +LVV+KM+Q LP
Sbjct: 339 CSEMFGGLDICAVKAVHSKDGRDYIIEVMDSSMPLIGEHVEEDRQLMADLVVSKMSQ-LP 397

Query: 420 RQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGP 479
                   PG    G  PSP   P   Q   + A  P Q +  PQ G PQP P PQ    
Sbjct: 398 -------MPG----GTAPSP-LRPWAPQI--KSAKSPGQAQLGPQLGQPQPRPPPQANLS 443

Query: 480 P 480
           P
Sbjct: 444 P 444


>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
           sapiens]
          Length = 309

 Score =  134 bits (336), Expect = 4e-31
 Identities = 107/294 (36%), Positives = 123/294 (41%), Gaps = 43/294 (14%)

Query: 405 LIVELVVNKMAQALPRQRQRDASP--------GRGSHG-----QTPSPGALPLGR--QTS 449
           L V L+    AQ+L     ++ SP        GR   G     +TP P   P GR  Q  
Sbjct: 6   LSVALLALSSAQSLNEDVSQEESPSVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGG 65

Query: 450 QQPAGPPAQ----QRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPL- 504
            Q  GPP +    + PPPQGG    GP P R G P  Q  PPQG     G  P  G P  
Sbjct: 66  NQSQGPPPRPGKPEGPPPQGGNQSQGP-PPRPGKPEGQ--PPQGGNQSQGPPPRPGKPEG 122

Query: 505 --PQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPAS-------PSPQ 555
             PQ        P +P     PP QG G QS+     PG P    P          P P 
Sbjct: 123 PPPQGGNQSQGPPPRPGKPEGPPPQG-GNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPG 181

Query: 556 RQAGPP-QATRQTSVSGPAPPKASGAPP-GGQQRQGPPQKPPGPAGPTRQASQA--GPVP 611
           +  GPP Q   Q+    P P K  G PP GG Q QGPP +P  P GP  Q      GP P
Sbjct: 182 KPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPP 241

Query: 612 RTG----PPTTQQPRPSGPGPAGRPK--PQLAQKPSQDVPPPATAAAGGPPHPQ 659
             G    PP  +  +P  P P GRP+  P     P Q +PPPA    G PP PQ
Sbjct: 242 HPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQ 295



 Score = 84.3 bits (207), Expect = 3e-16
 Identities = 81/241 (33%), Positives = 97/241 (40%), Gaps = 51/241 (21%)

Query: 419 PRQRQRDASPGRG---SHGQTPSPGALPLGR--QTSQQPAGPPAQ----QRPPPQGG--- 466
           PR  + +  P +G   S G  P PG  P G+  Q   Q  GPP +    + PPPQGG   
Sbjct: 73  PRPGKPEGPPPQGGNQSQGPPPRPGK-PEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQS 131

Query: 467 ---PPQPGP--------GPQRQGPPLQ----QRPPPQGQQHLSGLGPPAGSPL---PQRL 508
              PP+PG         G Q QGPP +    + PPPQG     G  P  G P    PQ  
Sbjct: 132 QGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGG 191

Query: 509 PSPTSAPQQPASQAAPPTQGQGRQSR---PVAGGPGAPPAAR------PPASPSPQRQAG 559
                 P +P     PP QG G QS+   P  G P  PP+        PP  P P +  G
Sbjct: 192 NQSQGPPPRPGKPEGPPPQG-GNQSQGPPPRPGKPEGPPSQGGNKPQGPP--PHPGKPQG 248

Query: 560 PPQATRQTSVSGPAPPKASGAPP-GGQQRQ------GPPQ-KPPGPAGPTRQASQAGPVP 611
           PP          P P +  G PP GG  +Q      G PQ  PP P G        G  P
Sbjct: 249 PPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQPP 308

Query: 612 R 612
           +
Sbjct: 309 Q 309



 Score = 30.8 bits (68), Expect = 4.5
 Identities = 16/47 (34%), Positives = 20/47 (42%), Gaps = 1/47 (2%)

Query: 27  RPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGG 73
           +P+ PPP  G  S G  P PG    +   G   +  P  P PG   G
Sbjct: 77  KPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGP-PPRPGKPEG 122



 Score = 30.8 bits (68), Expect = 4.5
 Identities = 17/47 (36%), Positives = 19/47 (40%), Gaps = 1/47 (2%)

Query: 27  RPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGG 73
           +P+ PPP  G  S G  P PG      S G      P  P PG   G
Sbjct: 203 KPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGP-PPHPGKPQG 248



 Score = 30.8 bits (68), Expect = 4.5
 Identities = 21/65 (32%), Positives = 23/65 (35%), Gaps = 8/65 (12%)

Query: 16  NLPNGYMTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSG-------VAPAASPAAPSP 68
           N P G      +PQ PPP  G + P   P PG        G         PA  P  P P
Sbjct: 234 NKPQGPPPHPGKPQGPPPQEG-NKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPP 292

Query: 69  GSSGG 73
              GG
Sbjct: 293 PPQGG 297


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score =  133 bits (334), Expect = 6e-31
 Identities = 111/293 (37%), Positives = 131/293 (44%), Gaps = 33/293 (11%)

Query: 405 LIVELVVNKMAQALPRQRQRDASPGR-GSHGQTPSPGALPLGRQTSQQPAGPPAQQRPP- 462
           L V L+    AQ L     ++ SP     + Q PSP       Q   +P GPP    PP 
Sbjct: 6   LSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSP-------QGGNKPQGPPP---PPG 55

Query: 463 -PQGGPPQPGPGPQRQGPPLQ-QRPPPQGQQHLSGLGPPAG--SPLPQRLPSPTSAPQQP 518
            PQG PPQ G  PQ   PP + Q PPPQG +  S   PP     P PQ    P   P  P
Sbjct: 56  KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP 115

Query: 519 ASQAAPPTQGQGR-QSRPVAGGPGAPPA----ARPPASPSPQRQAGPPQATRQTSVSGPA 573
                PP QG  R Q  P  G P  PP     +R P SP  + Q  PPQ   Q     P 
Sbjct: 116 GKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPP 175

Query: 574 PPKASGAPP-GGQQRQGPPQ--KPPGPA--GPTRQASQAGPVPRTGPPTTQQPRPSGPGP 628
           P K  G PP GG++ QGPP   KP GP   G   ++SQ+ P    GPP     +P GP P
Sbjct: 176 PGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPP 235

Query: 629 A-GRPK---PQLAQKPSQDVPPPATAAAGGPPHPQLNKSQSLTNAFNLPEPAP 677
             G+P+   PQ   KP Q  PPP      GPP    +KSQS  +    P+  P
Sbjct: 236 PPGKPQGPPPQGGNKP-QGPPPPGK--PQGPPAQGGSKSQSARSPPGKPQGPP 285



 Score =  128 bits (321), Expect = 2e-29
 Identities = 96/264 (36%), Positives = 111/264 (42%), Gaps = 24/264 (9%)

Query: 416 QALPRQRQRDASPGRGSHGQTP-SPGALPLGR--QTSQQPAGPPAQQRPP--PQGGPPQP 470
           Q  P   +    P +G   ++P SP   P G   Q   QP GPP    PP  PQG PPQ 
Sbjct: 69  QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPP---PPGKPQGPPPQG 125

Query: 471 GPGPQRQGPPLQ-QRPPPQGQQHLSGLGPPAG--SPLPQRLPSPTSAPQQPASQAAPPTQ 527
           G  PQ   PP + Q PPPQG +  S   PP     P PQ    P   P  P     PP Q
Sbjct: 126 GNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 185

Query: 528 GQGR-QSRPVAGGPGAPPA----ARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPP 582
           G  + Q  P  G P  PP     +R   SP  + Q  PPQ   Q     P P K  G PP
Sbjct: 186 GGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 245

Query: 583 -GGQQRQGP-----PQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQL 636
            GG + QGP     PQ PP   G   Q++++ P    GPP  +   P GP P     PQ 
Sbjct: 246 QGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQ 305

Query: 637 AQKPSQDVP--PPATAAAGGPPHP 658
            Q P    P  PP     G P  P
Sbjct: 306 PQAPPAGQPQGPPRPPQGGRPSRP 329



 Score = 76.3 bits (186), Expect = 9e-14
 Identities = 73/211 (34%), Positives = 87/211 (41%), Gaps = 51/211 (24%)

Query: 497 GP-PAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQ 555
           GP P G   PQ  P P   PQ P     PP  G   Q  P  G P  PP  +   S SP+
Sbjct: 38  GPSPQGGNKPQGPPPPPGKPQGP-----PPQGGNKPQGPPPPGKPQGPPP-QGDKSRSPR 91

Query: 556 RQAGPPQATRQTSVSGPAPPKASG----------------APPGGQQRQGPPQKPPG-PA 598
              G PQ           PP   G                 P GG + QGPP  PPG P 
Sbjct: 92  SPPGKPQG----------PPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPP--PPGKPQ 139

Query: 599 GPTRQASQAGPVPRTGPPTTQQPRPSG-------PGPAGRPK---PQLAQKPSQDVPPPA 648
           GP  Q  ++   PR+ P   Q P P G       P P G+P+   PQ  +KP Q  PPP 
Sbjct: 140 GPPPQGDKSRS-PRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKP-QGPPPPG 197

Query: 649 TAAAGGPPHPQLNKSQSLTNAFNLPEPAPPR 679
                GPP PQ +KS+S  +    P+  PP+
Sbjct: 198 KPQ--GPP-PQGDKSRSSQSPPGKPQGPPPQ 225



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 36/127 (28%), Positives = 44/127 (34%), Gaps = 30/127 (23%)

Query: 553 SPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPR 612
           SP   AG PQ        GP+P        GG + QGPP  P  P GP  Q         
Sbjct: 28  SPSLIAGNPQ--------GPSPQ-------GGNKPQGPPPPPGKPQGPPPQGGN------ 66

Query: 613 TGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLNKSQSLTNAFNL 672
                    +P GP P G+P+    Q      P        GPP    N+ Q        
Sbjct: 67  ---------KPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK 117

Query: 673 PEPAPPR 679
           P+  PP+
Sbjct: 118 PQGPPPQ 124



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 19/58 (32%), Positives = 22/58 (37%), Gaps = 5/58 (8%)

Query: 16  NLPNGYMTDLQRPQPPPP-----PPGAHSPGATPGPGTATAERSSGVAPAASPAAPSP 68
           N P G      +PQ PPP     P G   PG   GP     +  S  +P   P  P P
Sbjct: 167 NQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPP 224



 Score = 31.6 bits (70), Expect = 2.6
 Identities = 15/42 (35%), Positives = 17/42 (40%), Gaps = 5/42 (11%)

Query: 27 RPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSP 68
          +PQ PPPP     PG   GP      +  G  P   P  P P
Sbjct: 46 KPQGPPPP-----PGKPQGPPPQGGNKPQGPPPPGKPQGPPP 82



 Score = 31.2 bits (69), Expect = 3.4
 Identities = 19/58 (32%), Positives = 22/58 (37%), Gaps = 5/58 (8%)

Query: 16  NLPNGYMTDLQRPQPPPP-----PPGAHSPGATPGPGTATAERSSGVAPAASPAAPSP 68
           N P G      +PQ PPP     P G   PG   GP     +  S  +P   P  P P
Sbjct: 45  NKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPP 102



 Score = 31.2 bits (69), Expect = 3.4
 Identities = 19/58 (32%), Positives = 22/58 (37%), Gaps = 5/58 (8%)

Query: 16  NLPNGYMTDLQRPQPPPP-----PPGAHSPGATPGPGTATAERSSGVAPAASPAAPSP 68
           N P G      +PQ PPP     P G   PG   GP     +  S  +P   P  P P
Sbjct: 106 NQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPP 163



 Score = 30.4 bits (67), Expect = 5.9
 Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 10/56 (17%)

Query: 27  RPQPPPPPPG---------AHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGG 73
           +PQ PPPPPG          + P   P PG      + G + + S  +P PG   G
Sbjct: 229 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSP-PGKPQG 283



 Score = 30.0 bits (66), Expect = 7.7
 Identities = 16/48 (33%), Positives = 17/48 (35%), Gaps = 6/48 (12%)

Query: 27  RPQPPPPPPGAHSPGATPGPGTAT------AERSSGVAPAASPAAPSP 68
           +PQ PPP  G    G  P PG           R  G  P   P  P P
Sbjct: 96  KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPP 143


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score =  130 bits (327), Expect = 4e-30
 Identities = 111/302 (36%), Positives = 131/302 (43%), Gaps = 34/302 (11%)

Query: 404 QLIVELVVNKMAQALPRQRQRDASPGRGSHGQ-TPSPGALPLGR--QTSQQPAGPPAQQR 460
           Q + E V  + + +L     + A P  G+  Q  PSP   P G   Q   QP GPP    
Sbjct: 17  QNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPP--- 73

Query: 461 PP--PQGGPPQPGPGPQRQGPPLQ-QRPPPQGQQHLSGLGPPAG--SPLPQRLPSPTSAP 515
           PP  PQG PPQ G  PQ   PP + Q PPPQG +  S   PP     P PQ    P   P
Sbjct: 74  PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPP 133

Query: 516 QQPASQAAPPTQGQGR-QSRPVAGGPGAPPA-----ARPPASPSPQRQAGPPQATRQTSV 569
             P     PP QG  + Q  P  G P  PP      +R   SP  + Q  PPQ   Q   
Sbjct: 134 PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQG 193

Query: 570 SGPAPPKASGAPP-GGQQRQGPPQKPPG-PAGPTRQASQAGPVPRTGPPTTQQPRPSG-- 625
             P P K  G PP GG + QGPP  PPG P GP  Q        R+ P   Q P P G  
Sbjct: 194 PPPPPGKPQGPPPQGGNKPQGPP--PPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGN 251

Query: 626 -----PGPAGRPK---PQLAQKPSQDVPPPATAAAGGPPHPQLNKSQSLTNAFNLPEPAP 677
                P P G+P+   PQ   KP Q  PPP      GPP    +KS+S  +    P+  P
Sbjct: 252 QPQGPPPPPGKPQGPPPQGGNKP-QGPPPPGKPQ--GPPPQGGSKSRSSRSPPGKPQGPP 308

Query: 678 PR 679
           P+
Sbjct: 309 PQ 310



 Score =  123 bits (308), Expect = 7e-28
 Identities = 102/287 (35%), Positives = 123/287 (42%), Gaps = 31/287 (10%)

Query: 416 QALPRQRQRDASPGRGSHGQTP-SPGALPLGR--QTSQQPAGPPAQQRPP--PQGGPPQP 470
           Q  P   +    P +G   ++P SP   P G   Q   QP GPP    PP  PQG PPQ 
Sbjct: 90  QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPP---PPGKPQGPPPQG 146

Query: 471 GPGPQRQGPPLQ-QRPPPQGQQHLSGLGPPAGSPL---PQRLPSPTSAPQQPASQAAPPT 526
           G  PQ   PP + Q PPPQG         P G P    PQ    P   P  P     PP 
Sbjct: 147 GNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 206

Query: 527 QGQGR-QSRPVAGGPGAPPA-----ARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGA 580
           QG  + Q  P  G P  PP      ++   SP  + Q  PPQ   Q     P P K  G 
Sbjct: 207 QGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 266

Query: 581 PP-GGQQRQGPP-----QKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPA-GRPK 633
           PP GG + QGPP     Q PP   G   ++S++ P    GPP     +P GP P  G+P+
Sbjct: 267 PPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 326

Query: 634 ---PQLAQKPSQDVPPPATAAAGGPPHPQLNKSQSLTNAFNLPEPAP 677
              PQ   KP Q  PPP      GPP    +KS+S  +    P+  P
Sbjct: 327 GPPPQGGNKP-QGPPPPGK--PQGPPPQGGSKSRSARSPPGKPQGPP 370



 Score =  122 bits (306), Expect = 1e-27
 Identities = 94/280 (33%), Positives = 108/280 (38%), Gaps = 40/280 (14%)

Query: 419 PRQRQRDASPGRGSHGQTPSPGALPLG------------RQTSQQPAGPPAQQRPPPQGG 466
           P  + +   P  G+  Q P P   P G            R    +P GPP Q    PQG 
Sbjct: 135 PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGP 194

Query: 467 PPQPG----PGPQR----QGPP---LQQRPPPQGQQHLSGLGPPAGSPL---PQRLPSPT 512
           PP PG    P PQ     QGPP     Q PPPQG         P G P    PQ    P 
Sbjct: 195 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQ 254

Query: 513 SAPQQPASQAAPPTQGQGR-QSRPVAGGPGAPPA-----ARPPASPSPQRQAGPPQATRQ 566
             P  P     PP QG  + Q  P  G P  PP      +R   SP  + Q  PPQ   Q
Sbjct: 255 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQ 314

Query: 567 TSVSGPAPPKASGAPP-GGQQRQGP-----PQKPPGPAGPTRQASQAGPVPRTGPPTTQQ 620
                P P K  G PP GG + QGP     PQ PP   G   +++++ P    GPP  + 
Sbjct: 315 PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEG 374

Query: 621 PRPSGPGPAGRPKPQLAQKPSQDVP--PPATAAAGGPPHP 658
             P GP P     PQ  Q P    P  PP     G P  P
Sbjct: 375 NNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 414



 Score =  117 bits (294), Expect = 3e-26
 Identities = 104/305 (34%), Positives = 117/305 (38%), Gaps = 41/305 (13%)

Query: 421 QRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQ-------QRPP--PQGGPPQPG 471
           Q Q    P     G  P  G  P G     +P GPP Q       + PP  PQG PPQ G
Sbjct: 67  QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGG 126

Query: 472 PGPQRQGPP--LQQRPPPQGQQHLSGLGPPAG--SPLPQRLPSPTSAPQQPASQAAPPTQ 527
             PQ   PP    Q PPPQG     G  PP     P PQ      S+   P     PP Q
Sbjct: 127 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQ 186

Query: 528 G--QGRQSRPVAGGPGAPPAA---RPPASPSPQRQAGPPQATRQTSVSGPAPP-KASGAP 581
           G  Q +   P  G P  PP     +P   P P +  GPP      S S  +PP K  G P
Sbjct: 187 GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPP 246

Query: 582 P-GGQQRQGPP------QKPP-----GPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPA 629
           P GG Q QGPP      Q PP      P GP       GP P+ G  +     P  PG  
Sbjct: 247 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSP--PGKP 304

Query: 630 GRPKPQLAQKPSQDVPPPATAAAGGPPHPQLNKSQSLTNAFNLPEPAPPRPSLSQDEVKA 689
             P PQ   +P    PPP      GPP    NK Q        P P  P+    Q   K+
Sbjct: 305 QGPPPQGGNQPQG--PPPPPGKPQGPPPQGGNKPQ------GPPPPGKPQGPPPQGGSKS 356

Query: 690 ETIRS 694
            + RS
Sbjct: 357 RSARS 361



 Score =  109 bits (273), Expect = 8e-24
 Identities = 91/263 (34%), Positives = 107/263 (40%), Gaps = 39/263 (14%)

Query: 416 QALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQ-QRPPPQGGPPQPGPGP 474
           Q  P Q    +   R   G+   P   P G    Q P  PP + Q PPPQGG    GP P
Sbjct: 160 QGPPPQGDNKSRSSRSPPGKPQGPP--PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 217

Query: 475 --QRQGPPLQ---------------QRPPPQGQQHLSGLGPPAGSPL--PQRLPSPTSAP 515
             + QGPP Q               Q PPPQG     G  PP G P   P +  +    P
Sbjct: 218 PGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP 277

Query: 516 QQPASQAAPPTQG--QGRQSRPVAGGPGAPP--AARPPASPSP---QRQAGPPQATRQTS 568
             P     PP QG  + R SR   G P  PP      P  P P   + Q  PPQ   +  
Sbjct: 278 PPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 337

Query: 569 VSGPAPP-KASGAPPGGQQRQGPPQKPPG-PAGPTRQAS---QAGPVPRTGPPTTQQPRP 623
             GP PP K  G PP G  +    + PPG P GP +Q     Q  P P  G P   Q  P
Sbjct: 338 --GPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP 395

Query: 624 SGPGPAGRPKPQLAQKPSQDVPP 646
           +G  P G P+P    +PS+  PP
Sbjct: 396 AGQ-PQGPPRPPQGGRPSR--PP 415



 Score = 99.8 bits (247), Expect = 8e-21
 Identities = 82/233 (35%), Positives = 92/233 (39%), Gaps = 26/233 (11%)

Query: 421 QRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQ--------QRPP--PQGGPPQP 470
           Q Q    P     G  P  G  P G     +P GPP Q        + PP  PQG PPQ 
Sbjct: 190 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQG 249

Query: 471 GPGPQRQGPP--LQQRPPPQGQQHLSGLGPPAG--SPLPQRLPSPTSAPQQPASQAAPPT 526
           G  PQ   PP    Q PPPQG     G  PP     P PQ      S+   P     PP 
Sbjct: 250 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPP 309

Query: 527 QG--QGRQSRPVAGGPGAPPAA---RPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAP 581
           QG  Q +   P  G P  PP     +P   P P +  GPP      S S  +PP     P
Sbjct: 310 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGP 369

Query: 582 PGGQQRQGPPQKPPGPAGPTRQASQAGPVPRT-GPPTTQQPRPSGPGPAGRPK 633
           P  QQ    PQ PP PAG   Q  QA P  +  GPP      P G  P+  P+
Sbjct: 370 P--QQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRP----PQGGRPSRPPQ 416



 Score = 38.5 bits (88), Expect = 0.022
 Identities = 31/84 (36%), Positives = 37/84 (44%), Gaps = 12/84 (14%)

Query: 412 NKMAQALPRQRQRDASPGRGSHGQTP-SPGALPLG--RQTSQQPAGPPAQQRPPPQGGP- 467
           NK     P  + +   P  GS  ++  SP   P G  +Q    P GPP    PP  G P 
Sbjct: 334 NKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPP----PPAGGNPQ 389

Query: 468 -PQPGPGPQRQGPPLQQRPPPQGQ 490
            PQ  P  Q QGPP   RPP  G+
Sbjct: 390 QPQAPPAGQPQGPP---RPPQGGR 410



 Score = 32.0 bits (71), Expect = 2.0
 Identities = 20/55 (36%), Positives = 22/55 (40%), Gaps = 7/55 (12%)

Query: 27  RPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGGGFFSSLS 81
           +PQ PPPP     PG   GP      +  G  P   P  P P   GG    SS S
Sbjct: 252 QPQGPPPP-----PGKPQGPPPQGGNKPQGPPPPGKPQGPPP--QGGSKSRSSRS 299



 Score = 31.6 bits (70), Expect = 2.6
 Identities = 18/59 (30%), Positives = 21/59 (35%), Gaps = 6/59 (10%)

Query: 16  NLPNGYMTDLQRPQPPPPPPGAHSPGATPGPGTAT------AERSSGVAPAASPAAPSP 68
           N P G  +   +PQ PPP  G    G  P PG           +  G  P   P  P P
Sbjct: 45  NKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP 103



 Score = 31.2 bits (69), Expect = 3.4
 Identities = 19/58 (32%), Positives = 22/58 (37%), Gaps = 5/58 (8%)

Query: 16  NLPNGYMTDLQRPQPPPP-----PPGAHSPGATPGPGTATAERSSGVAPAASPAAPSP 68
           N P G      +PQ PPP     P G   PG   GP     +  S  +P   P  P P
Sbjct: 66  NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPP 123



 Score = 31.2 bits (69), Expect = 3.4
 Identities = 15/42 (35%), Positives = 17/42 (40%), Gaps = 5/42 (11%)

Query: 27  RPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSP 68
           +PQ PPPP     PG   GP      +  G  P   P  P P
Sbjct: 128 QPQGPPPP-----PGKPQGPPPQGGNKPQGPPPPGKPQGPPP 164



 Score = 31.2 bits (69), Expect = 3.4
 Identities = 15/42 (35%), Positives = 17/42 (40%), Gaps = 5/42 (11%)

Query: 27  RPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSP 68
           +PQ PPPP     PG   GP      +  G  P   P  P P
Sbjct: 190 QPQGPPPP-----PGKPQGPPPQGGNKPQGPPPPGKPQGPPP 226



 Score = 31.2 bits (69), Expect = 3.4
 Identities = 15/42 (35%), Positives = 17/42 (40%), Gaps = 5/42 (11%)

Query: 27  RPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSP 68
           +PQ PPPP     PG   GP      +  G  P   P  P P
Sbjct: 314 QPQGPPPP-----PGKPQGPPPQGGNKPQGPPPPGKPQGPPP 350



 Score = 30.8 bits (68), Expect = 4.5
 Identities = 20/59 (33%), Positives = 23/59 (38%), Gaps = 6/59 (10%)

Query: 16  NLPNGYMTDLQRPQPPPP-----PPGAHSPGATPGPGTATAERS-SGVAPAASPAAPSP 68
           N P G      +PQ PPP     P G   PG   GP      +S S  +P   P  P P
Sbjct: 251 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPP 309



 Score = 30.0 bits (66), Expect = 7.7
 Identities = 20/59 (33%), Positives = 23/59 (38%), Gaps = 6/59 (10%)

Query: 16  NLPNGYMTDLQRPQPPPP-----PPGAHSPGATPGPGTATAERS-SGVAPAASPAAPSP 68
           N P G      +PQ PPP     P G   PG   GP      +S S  +P   P  P P
Sbjct: 127 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPP 185



 Score = 30.0 bits (66), Expect = 7.7
 Identities = 20/59 (33%), Positives = 23/59 (38%), Gaps = 6/59 (10%)

Query: 16  NLPNGYMTDLQRPQPPPP-----PPGAHSPGATPGPGTATAERS-SGVAPAASPAAPSP 68
           N P G      +PQ PPP     P G   PG   GP      +S S  +P   P  P P
Sbjct: 189 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPP 247


>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
           sapiens]
          Length = 247

 Score =  115 bits (289), Expect = 1e-25
 Identities = 89/252 (35%), Positives = 105/252 (41%), Gaps = 54/252 (21%)

Query: 445 GRQTSQQPAGPPAQQRPPPQGGPPQ---PGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAG 501
           G+   ++P G    QRPPP  G PQ   P  G Q QGPP    PPP         G P G
Sbjct: 34  GKPEGRRPQGGNQPQRPPPPPGKPQGPPPQGGNQSQGPP----PPP---------GKPEG 80

Query: 502 SPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPP 561
            P PQ        P  P     PP QG G QS+      G PP   PP  P    +  PP
Sbjct: 81  RP-PQGGNQSQGPPPHPGKPERPPPQG-GNQSQ------GTPP---PPGKP----ERPPP 125

Query: 562 QATRQTSVSGPAPPKASGAPP-GGQQRQGPPQKPPGPAGPTRQ------ASQAGPVPRTG 614
           Q   Q+    P P K    PP GG Q QGPP  P  P GP  Q      ++++ P    G
Sbjct: 126 QGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPPGKPQG 185

Query: 615 PPTTQQPRPSGPGPAGRPK--PQLAQKPSQDVPPPATAAAGGPPHPQLNKSQSLTNAFNL 672
           PP  +  +P GP P G+P+  P     P Q   PPA    G PP PQ  +          
Sbjct: 186 PPQQEGNKPQGPPPPGKPQGPPPAGGNPQQPQAPPAGKPQGPPPPPQGGR---------- 235

Query: 673 PEPAPPRPSLSQ 684
               PPRP+  Q
Sbjct: 236 ----PPRPAQGQ 243



 Score =  102 bits (255), Expect = 9e-22
 Identities = 80/225 (35%), Positives = 91/225 (40%), Gaps = 28/225 (12%)

Query: 428 PGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQ---PGPGPQRQGPP---- 480
           P  G+  Q P P   P G+     P G    Q PPP  G P+   P  G Q QGPP    
Sbjct: 41  PQGGNQPQRPPP---PPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPG 97

Query: 481 LQQRPPPQGQQHLSGLGPPAGS---PLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVA 537
             +RPPPQG     G  PP G    P PQ        P  P     PP QG G QS+   
Sbjct: 98  KPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQG-GNQSQ--- 153

Query: 538 GGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGP 597
              G PP    P  P PQ +    ++ R        PP+  G  P G    G PQ PP P
Sbjct: 154 ---GPPPHPGKPEGPPPQ-EGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGPP-P 208

Query: 598 AGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQ 642
           AG   Q  QA   P  G P    P P G  P   P+P   Q+P Q
Sbjct: 209 AGGNPQQPQA---PPAGKPQGPPPPPQGGRP---PRPAQGQQPPQ 247



 Score = 89.7 bits (221), Expect = 8e-18
 Identities = 67/178 (37%), Positives = 72/178 (40%), Gaps = 20/178 (11%)

Query: 424 RDASPGRGSHGQTPSPGAL----PLGRQTSQQPAGPPAQ-QRPPPQGGPPQPGPGPQRQG 478
           R    G  S G  P PG      P G   SQ    PP + +RPPPQGG     P P    
Sbjct: 81  RPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPP--- 137

Query: 479 PPLQQRPPPQGQQHLSGLGPPAG---SPLPQRLPSPTSAPQQPASQAAPPTQ-GQGRQSR 534
           P   +RPPPQG     G  P  G    P PQ      SA   P     PP Q G   Q  
Sbjct: 138 PGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGP 197

Query: 535 PVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQ 592
           P  G P  P    PPA  +PQ+   PP    Q    GP PP   G PP   Q Q PPQ
Sbjct: 198 PPPGKPQGP----PPAGGNPQQPQAPPAGKPQ----GPPPPPQGGRPPRPAQGQQPPQ 247



 Score = 30.0 bits (66), Expect = 7.7
 Identities = 16/43 (37%), Positives = 18/43 (41%), Gaps = 1/43 (2%)

Query: 27 RPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPG 69
          +PQ PPP  G  S G  P PG        G   +  P  P PG
Sbjct: 56 KPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGP-PPHPG 97


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score =  100 bits (250), Expect = 4e-21
 Identities = 99/321 (30%), Positives = 116/321 (36%), Gaps = 51/321 (15%)

Query: 406  IVELVVNKMAQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAG---PPAQQRPP 462
            +V L   K   A P  +Q  A     S  +       P G   S  P G   PPA   P 
Sbjct: 890  VVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPS 949

Query: 463  PQGGPPQPGPGPQRQGPPLQQRPPPQG----QQHLSGLGPPAGSPLPQR----LPSPTSA 514
            P+GGP  P P      PP    P P+G            PPA +P   +     PSP  A
Sbjct: 950  PKGGPATPSP-KWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGA 1008

Query: 515  PQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPP-------ASPSPQRQAGPPQATRQT 567
            P  PA    PP+      + P   G   PPAA PP       A+P P+     P AT  +
Sbjct: 1009 PTPPA--VTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS 1066

Query: 568  SVSGPAPPKASGAP-------------PGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTG 614
               GPA P   GAP             P     +G P  PP    P+ +   A P P  G
Sbjct: 1067 PKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPM-PPAATPPSPKGGLATP-PHKG 1124

Query: 615  PPTT---QQPRPSG----PGPAGRPKPQLAQKPSQD----VPPP---ATAAAGGPPHPQL 660
             PTT     P P G    P P G P    A  PS       PPP    T  A  PP P+ 
Sbjct: 1125 APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKG 1184

Query: 661  N-KSQSLTNAFNLPEPAPPRP 680
               + S   A   P   PP P
Sbjct: 1185 GLATPSPKGAPTTPAATPPSP 1205



 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 91/289 (31%), Positives = 107/289 (37%), Gaps = 50/289 (17%)

Query: 428  PGRGSHGQTPSPGAL----PLGRQTSQQPAG---PPAQQRPPPQGGP----PQPGPGPQR 476
            P   S    P+P A     P G   +  P G   PPA   P P+GGP    P+  P P  
Sbjct: 954  PATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPA 1013

Query: 477  QGPPLQQRPP-----PQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGR 531
              PP  +  P     P+G        PP+    P   P P  AP  PA+    P   +G 
Sbjct: 1014 VTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSP---KGG 1070

Query: 532  QSRPVAGGPGAPPAARPP------ASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQ 585
             + P   G   PPAA PP      A+PSP+    PP AT  +   G A P   GAP    
Sbjct: 1071 PATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTT-- 1128

Query: 586  QRQGPPQKPPGPAGPTRQASQAGPVPRTGP--PTTQQPRPSG----PGPAGRPKPQLAQK 639
                P   PP P G       A P P+  P  P    P P G    P P G P    A  
Sbjct: 1129 ----PAATPPSPKG-----GLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1179

Query: 640  PSQD----VPPP---ATAAAGGPPHPQLN-KSQSLTNAFNLPEPAPPRP 680
            PS       P P    T  A  PP P+    + S   A   P   PP P
Sbjct: 1180 PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP 1228



 Score = 88.6 bits (218), Expect = 2e-17
 Identities = 93/291 (31%), Positives = 105/291 (36%), Gaps = 53/291 (18%)

Query: 430  RGSHGQTPSP-GALPLGRQTSQQPAGPPAQQRPPPQGGP-------PQPGPGPQRQGPPL 481
            +GS   TP P GA      T   P G PA   P P+G P       P P  GP    P L
Sbjct: 1020 KGSPAATPFPKGASTPPAATPPSPKGSPAAT-PLPKGAPTTPAATLPSPKGGPAT--PSL 1076

Query: 482  QQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPG 541
            +  P P      S  G PA        PSP  AP  PA  A PP+   G  + P  G P 
Sbjct: 1077 KGAPTPPAATPPSPKGGPA-------TPSPKGAPMPPA--ATPPSPKGGLATPPHKGAP- 1126

Query: 542  APPAARPP------ASPSPQRQAGPPQATRQTSVSGPAPPKASGA----------PPGGQ 585
              PAA PP      A+P P+     P AT  +   G A P   GA          P GG 
Sbjct: 1127 TTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL 1186

Query: 586  QRQGPPQKPPGPAG--PTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQD 643
                P   P  PA   P+ +   A P P+  P T     PS  G    P P+ A      
Sbjct: 1187 ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1246

Query: 644  VPP-----PATAAAGGPPHPQLNKSQSLTNAF------NLPEPA---PPRP 680
             PP     PAT    G P P      SL            P PA   PP P
Sbjct: 1247 TPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSP 1297



 Score = 85.9 bits (211), Expect = 1e-16
 Identities = 75/242 (30%), Positives = 87/242 (35%), Gaps = 32/242 (13%)

Query: 464  QGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLG---PPAGSPLPQ--RLPSPTSAPQQP 518
            QG    P        P  +  P P     LS  G   PP  +P P    LP P   P  P
Sbjct: 844  QGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATP 903

Query: 519  ASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKAS 578
            A + AP         +     P AP     PASPSP+    PP AT  +   GPA P   
Sbjct: 904  APKQAPALSMTSSSPKKARATP-APKGI--PASPSPKGAPTPPAATPPSPKGGPATPSPK 960

Query: 579  GAPPGGQQRQGPPQKPPGP-AGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLA 637
             AP        P   PP P  GP   + +  P P    P + +  P+ P P G P P   
Sbjct: 961  WAP------TPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAV 1014

Query: 638  QKPSQDVPPPA--------TAAAGGPPHPQ-------LNKSQSLTNAFNLPEP--APPRP 680
              PS    P A        T  A  PP P+       L K    T A  LP P   P  P
Sbjct: 1015 TPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATP 1074

Query: 681  SL 682
            SL
Sbjct: 1075 SL 1076



 Score = 85.9 bits (211), Expect = 1e-16
 Identities = 78/255 (30%), Positives = 98/255 (38%), Gaps = 36/255 (14%)

Query: 428  PGRGSHGQTPSPGALPLGRQTSQQPAG---PPAQQRPPPQGG----PPQPGPGPQRQGPP 480
            P +G+     +    P G   +  P G    PA   P P+GG    PP+  P      PP
Sbjct: 1121 PHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP 1180

Query: 481  LQQ----RPPPQGQQHLSGLGPPAGSPLPQ---RLPSPTSAPQQPASQAAPPTQGQGRQS 533
              +     P P+G    +   P A  P P+     PSP  AP  PA  A PP+   G  +
Sbjct: 1181 SPKGGLATPSPKG----APTTPAATPPSPKGGLATPSPKGAPTTPA--ATPPSPKGGLAT 1234

Query: 534  RPVAGGPGAPPAARP-----PASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQ 588
                G P  P A  P     PA+P P+    PP AT  +   G A P   GAP       
Sbjct: 1235 PSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAP------N 1288

Query: 589  GPPQKPPGP-AGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPP- 646
                 PP P  GP     +  P P    P + +  P  P P G P P     PS    P 
Sbjct: 1289 PAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPT 1348

Query: 647  -PAT--AAAGGPPHP 658
             PAT  ++ GGP  P
Sbjct: 1349 LPATTPSSKGGPTTP 1363



 Score = 74.7 bits (182), Expect = 3e-13
 Identities = 79/294 (26%), Positives = 105/294 (35%), Gaps = 47/294 (15%)

Query: 430  RGSHGQTPSPGALPLGRQTSQQPAGPPAQQRP-----PPQGGPPQPGPGPQRQGPPLQQR 484
            +G     P  GA      T   P G PA   P     PP   PP P   P          
Sbjct: 1275 KGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSP--------GT 1326

Query: 485  PPPQGQQHLSGLGPPA--GSP-LPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPG 541
            PPP+G      + PP+  G+P LP   PS    P  P+S+  P         +   GGP 
Sbjct: 1327 PPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHK---GGPA 1383

Query: 542  APPAA--RPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQK----PP 595
              P +  R PA PSP+     P          P  PK + A P  ++    P K    PP
Sbjct: 1384 MTPPSPKRGPAIPSPKGDPTSPAVI-------PLSPKKAPATPVTREGAATPSKGDLTPP 1436

Query: 596  GPAGPTRQASQAGPVPRTGPPTTQQ------PRPSGPGPAGRPKP-QLAQKPSQDVPPPA 648
                 + + + A   P+ GP T         P  + P P   P P Q+A   S    P  
Sbjct: 1437 AVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPAT 1496

Query: 649  TAAAGGPPHPQLNKSQSLTNAFNLPEPAPPRPSLSQDEVKAETIRSLRKSFASL 702
             A  G P  P +  S         P+  P  PS  +D +        +K+ A+L
Sbjct: 1497 PAPMGAPTLPAVIPSS--------PKEVPATPSSRRDPIAPTATLLSKKTPATL 1542



 Score = 73.2 bits (178), Expect = 8e-13
 Identities = 70/230 (30%), Positives = 88/230 (38%), Gaps = 19/230 (8%)

Query: 436  TPSP-GALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLS 494
            TPSP GA      T   P G  A   P P+G P  P   P      L   P P+G     
Sbjct: 1188 TPSPKGAPTTPAATPPSPKGGLAT--PSPKGAPTTPAATPPSPKGGLAT-PSPKGAPTTP 1244

Query: 495  GLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSP 554
               PP+    P   P P  AP  PA  A PP+   G  + P  G P   PA   P SP  
Sbjct: 1245 AATPPSPKGGPAT-PPPKGAPTPPA--ATPPSLKGGLATPPHKGAPN--PAVVTPPSPKG 1299

Query: 555  QRQAGPPQ-ATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAG-----PTRQASQAG 608
                 PP+ A    + + P+P  + G PP       P   PP P G      T  +S+ G
Sbjct: 1300 GPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGG 1359

Query: 609  PVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHP 658
            P   T P + + P P    P+ +  P +   PS    P   +  G P  P
Sbjct: 1360 P---TTPSSKEGPTPPAATPSHKGGPAMT-PPSPKRGPAIPSPKGDPTSP 1405



 Score = 70.1 bits (170), Expect = 7e-12
 Identities = 79/292 (27%), Positives = 102/292 (34%), Gaps = 57/292 (19%)

Query: 438  SPGALPLGRQTSQQPAGP-PAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGL 496
            +P +L  G  T      P PA   PP   G P   P      PP    P P+G     G 
Sbjct: 1270 TPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSP---GT 1326

Query: 497  GPPAGSPLPQRL--PSPTSAPQQPA----SQAAPPTQGQGRQSRPVA------GGPGAPP 544
             PP G+P P  +  PSP   P  PA    S+  P T        P A      GGP   P
Sbjct: 1327 PPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTP 1386

Query: 545  AA--RPPASPSPQRQAGPPQATRQTSVSGPAPPKA-SGAPPGGQQRQGPPQKPP-----G 596
             +  R PA PSP+     P     +    PA P    GA    +    PP   P      
Sbjct: 1387 PSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKA 1446

Query: 597  PA------GPTRQASQAGP-VPRTGPPTTQQP--------------RPSGPGPAGRPK-P 634
            PA      GP   +S+  P +P   PP+ ++P               P+ P P G P  P
Sbjct: 1447 PATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLP 1506

Query: 635  QLAQKPSQDVP-----------PPATAAAGGPPHPQLNKSQSLTNAFNLPEP 675
             +     ++VP           P AT  +   P     K   +  A  +P P
Sbjct: 1507 AVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSP 1558



 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 72/271 (26%), Positives = 99/271 (36%), Gaps = 34/271 (12%)

Query: 413  KMAQALPRQRQRDASPGRGSHGQTPSPGALPLGRQ---TSQQPAGPPAQQRPPPQGGPPQ 469
            K A A P  R+  A+P +G    TP P   P+  +    +  P G PA   P  +G P  
Sbjct: 1413 KKAPATPVTREGAATPSKGD--LTP-PAVTPVSLKKAPATSAPKGGPAT--PSSKGDPTL 1467

Query: 470  PG--PGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSP-LPQRLPS-PTSAPQQPASQAAP- 524
            P   P   ++ P  +Q       +       P G+P LP  +PS P   P  P+S+  P 
Sbjct: 1468 PAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPI 1527

Query: 525  -PTQGQGRQSRPVAGGPGA---PPAA------RPPASPSPQRQAGPPQATRQTSVSGPAP 574
             PT     +  P    P     PPA       + PA P+P+     P +   +S     P
Sbjct: 1528 APTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTP 1587

Query: 575  PKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRP-K 633
                GAP   +    P    P P       +   P P  GP T        P P G P  
Sbjct: 1588 STYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPAT--------PAPKGTPTS 1639

Query: 634  PQLAQKPSQDVP--PPATAAAGGPPHPQLNK 662
            P +     +D P  P +     G   PQ +K
Sbjct: 1640 PPVTPSSLKDSPTSPASVTCKMGATVPQASK 1670



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 86/365 (23%), Positives = 113/365 (30%), Gaps = 115/365 (31%)

Query: 437  PSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPG--PGPQRQGP--PLQQRPPPQGQQH 492
            PSP   P  +Q +   +   A   P P G P  P   P   ++ P  P  +R P      
Sbjct: 1473 PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTAT 1532

Query: 493  LSGLGPPAGS-------PLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGP----G 541
            L     PA         P    +PSP   P  P  + AP T      S P A  P    G
Sbjct: 1533 LLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKG 1592

Query: 542  APPAAR---PPA--SPSPQRQAGPPQATRQTSVSGPAPPKASG---APP----------- 582
            AP       PPA  SPSP+    PP  T  +   GPA P   G   +PP           
Sbjct: 1593 APSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPT 1652

Query: 583  ------------------GGQQRQGP-----------PQKPPGPAGPTRQASQAGPVPRT 613
                              G   ++GP           P+  P    PTR+  Q      T
Sbjct: 1653 SPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSAT 1712

Query: 614  GPP---------------TTQQPRPSGP-------------------GPAGRPK-----P 634
             PP               +T  P P  P                   GP   P+     P
Sbjct: 1713 SPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTP 1772

Query: 635  QLAQKPSQDVPPPATAAAGGPPHPQLN-------------KSQSLTNAFNLPEPAPPRPS 681
              A    + +P P +A+    P P ++             K Q L ++  L   +P +P 
Sbjct: 1773 LTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPL 1832

Query: 682  LSQDE 686
               DE
Sbjct: 1833 APADE 1837



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 63/248 (25%), Positives = 79/248 (31%), Gaps = 18/248 (7%)

Query: 442 LPLGRQTSQQ-PAGPPAQQRPPPQG----GPPQPGPGPQRQGPPLQQRPPPQ---GQQHL 493
           LPL    S+  P  P  Q    P       P  P   P    PP    P  +   G  H 
Sbjct: 698 LPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHT 757

Query: 494 SGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPS 553
           S L P A SP  +  P+  S     AS     T        P   G    P  + P  P+
Sbjct: 758 SALAPVASSP--KECPTEDSGASATASSKGTLTY---LADSPSPLGVSVSPQTKRP--PT 810

Query: 554 PQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRT 613
            +  AGP       S S  +P +AS  P      QG    P     PT  + +  P P  
Sbjct: 811 KKGSAGPDTPIGNLS-SPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSA 869

Query: 614 GPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLNKSQSLTNAFNLP 673
             P +  P+     P   P P +   P     P   A    P     + S     A   P
Sbjct: 870 VTPLS--PKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAP 927

Query: 674 EPAPPRPS 681
           +  P  PS
Sbjct: 928 KGIPASPS 935



 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 60/243 (24%), Positives = 88/243 (36%), Gaps = 45/243 (18%)

Query: 470 PGPGPQRQGPPLQQRPPPQGQQHL----------SGLGPPAGSPLPQRLPSPTSAPQQPA 519
           PG   +      Q+ P PQ +  +          + LG P  +  P   P+P   P   A
Sbjct: 2   PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAA 61

Query: 520 SQAAP-PT--------------QGQGRQSRPVAGGPGAPP----AARPPASPSPQRQAGP 560
           +QA+P P+              Q     + P+   P AP        PP SP+    A P
Sbjct: 62  NQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASP 121

Query: 561 PQA-TRQTSVSGPAPPKASGAPPGGQQRQG--PPQKPPGPAGPTRQASQAG-------PV 610
             A T + + S  AP       P   Q+    PP     P  P+   +++G       P+
Sbjct: 122 MIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSP--PSVAVAESGSVITLSAPI 179

Query: 611 PRTGPPTTQQPRPSG--PGPAGRPKPQ--LAQKPSQDVPPPATAAAGGPPHPQLNKSQSL 666
             + P T     PS   P P G P P   ++  P   V P A+  +G    PQ   + +L
Sbjct: 180 APSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTL 239

Query: 667 TNA 669
             A
Sbjct: 240 AIA 242



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 80/373 (21%), Positives = 116/373 (31%), Gaps = 88/373 (23%)

Query: 413  KMAQALPRQRQRDASPG--RGSHGQTPSPGALPLGRQ-TSQQPAG---PPAQQRPPPQGG 466
            K A A P  ++  + P     ++   PSP  L +    TS  P     PPA   P P+ G
Sbjct: 1568 KEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKG 1627

Query: 467  PPQPGPGPQRQGPP-----LQQRP--PPQGQQHLSGLGPPAGSPLPQR-----------L 508
            P  P P      PP     L+  P  P      +    P A   LP +            
Sbjct: 1628 PATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVA 1687

Query: 509  PSPTSAPQQPA-SQAAPPTQGQGRQSRPVAGGPGAPPAARPP------------------ 549
            P+P S P   A ++  P T+     S P+   P A   ++ P                  
Sbjct: 1688 PAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSK 1747

Query: 550  ------ASPSPQRQAGPPQATRQTSVSGPA------------------------------ 573
                  AS SP+    PP++   T ++  A                              
Sbjct: 1748 TAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPV 1807

Query: 574  ---PPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAG 630
               PPK    P         P KP  PA          P P +G    Q    + P P  
Sbjct: 1808 PTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKS 1867

Query: 631  R----PKPQLAQKPSQDVPPPATAAAGGPPHPQLNKSQSLTNAFNLPEPAPPRPSLSQDE 686
                 P P   Q  +++     T +      P+L +  S T A            + ++ 
Sbjct: 1868 AGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDS-TQATTQQAQLAAAAEIDEEP 1926

Query: 687  V-KAETIRSLRKS 698
            V KA+  RS +K+
Sbjct: 1927 VSKAKQSRSEKKA 1939



 Score = 31.2 bits (69), Expect = 3.4
 Identities = 23/75 (30%), Positives = 31/75 (41%), Gaps = 5/75 (6%)

Query: 28   PQPPP--PPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGGGFFSSLSNAVK 85
            P PP   PP    SPG  P  G  T    +  +P  +P  P+   S  GG     + + K
Sbjct: 1310 PTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGG---PTTPSSK 1366

Query: 86   QTTAAAAATFSEQVG 100
            +     AAT S + G
Sbjct: 1367 EGPTPPAATPSHKGG 1381



 Score = 30.4 bits (67), Expect = 5.9
 Identities = 18/47 (38%), Positives = 22/47 (46%), Gaps = 6/47 (12%)

Query: 28   PQPPPPPPGAHSPG-----ATPGP-GTATAERSSGVAPAASPAAPSP 68
            P+  P PP A  P      ATP P G  T   ++  +P   PA PSP
Sbjct: 959  PKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSP 1005



 Score = 30.0 bits (66), Expect = 7.7
 Identities = 18/41 (43%), Positives = 22/41 (53%), Gaps = 3/41 (7%)

Query: 28   PQPPP--PPPGAHSPGATPGP-GTATAERSSGVAPAASPAA 65
            P PP   PP    SP ATP P G +T   ++  +P  SPAA
Sbjct: 1009 PTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAA 1049


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 99.0 bits (245), Expect = 1e-20
 Identities = 92/292 (31%), Positives = 118/292 (40%), Gaps = 45/292 (15%)

Query: 419 PRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQ--RPPPQGGPPQPGPGPQR 476
           P+ +Q D   G       PSP   P+ + T   P  PPAQQ      Q GP +P   P  
Sbjct: 281 PQTKQADIVRGESVKPSLPSPSKPPIQQPT---PGKPPAQQPGHEKSQPGPAKPPAQPSG 337

Query: 477 QGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPV 536
              PL Q+P         G   P   P     P  T  P QP   A PP Q  G + +P 
Sbjct: 338 LTKPLAQQP---------GTVKPPVQP-----PGTTKPPAQPLGPAKPPAQQTGSE-KPS 382

Query: 537 AGGPGAPPAARPP-ASPSPQRQAGPPQ-ATRQTSVSGP--------APPKASGAPPGGQQ 586
           +  PG    A+PP    +P +Q GP +  T+Q     P        +P KA G      Q
Sbjct: 383 SEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQ 442

Query: 587 RQGPPQKPPGPAGPTR-QASQAGPV-PRTGPPTTQQPRPSGPGPAGRPKPQL-------A 637
           + GP + P   AGP +  A Q GP  P +  P   +P P  PGPA +P PQ        +
Sbjct: 443 QPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPA-KPPPQQPGSAKPPS 501

Query: 638 QKPSQDVPPPAT--AAAGGPPHPQLNKSQSLTNAFNLP---EPAPPRPSLSQ 684
           Q+P    PPP     A   P  P   K  S       P   +P+P +PS  Q
Sbjct: 502 QQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQ 553



 Score = 97.1 bits (240), Expect = 5e-20
 Identities = 80/268 (29%), Positives = 102/268 (38%), Gaps = 22/268 (8%)

Query: 426 ASPGRGSHGQTPSPGALPLGRQ--TSQQPAGPPAQQRPPPQG-GPPQPGPGPQRQGPPLQ 482
           + PG       PS    PL +Q  T + P  PP   +PP Q  GP +P         P  
Sbjct: 324 SQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSS 383

Query: 483 QRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGA 542
           ++P P+         PP     P + P P   P Q      P  Q  G QS   A GP  
Sbjct: 384 EQPGPKALAQ-----PPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTK 438

Query: 543 PPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTR 602
            P  +P     P +QAGP + + Q +     P +  G      Q+ GP + PP   G  +
Sbjct: 439 TPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAK 498

Query: 603 QASQAGPVPRTGPPTTQQPRPSGPGP--AGRPKPQLAQ----KPSQDVPPPATAAAGGPP 656
             SQ    P +  P  QQP P+ P P   G  KP   Q    KPS   P PA      P 
Sbjct: 499 PPSQQ---PGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAK-----PS 550

Query: 657 HPQLNKSQSLTNAFNLPEPAPPRPSLSQ 684
             Q  K  S T +    +P    PS  Q
Sbjct: 551 AQQSTKPVSQTGSGKPLQPPTVSPSAKQ 578



 Score = 85.9 bits (211), Expect = 1e-16
 Identities = 77/244 (31%), Positives = 101/244 (41%), Gaps = 50/244 (20%)

Query: 436 TPSPGALPLG------------RQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQ 483
           T  P A PLG            + +S+QP GP A  +PP  G  P   PGP +  PP QQ
Sbjct: 358 TTKPPAQPLGPAKPPAQQTGSEKPSSEQP-GPKALAQPPGVGKTPAQQPGPAK--PPTQQ 414

Query: 484 RPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQ-PASQAAP-------------PTQGQ 529
              P+      GL  PA +P P + P     P + PA QA P             P+Q  
Sbjct: 415 VGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLP 474

Query: 530 G-RQSRPVAGGPGAPPAARPPASPSPQRQAG----PPQATRQTSVSGPAPPKASGAPPGG 584
           G  +  P   GP  PP  +P ++  P +Q G    PPQ         P P K S   PG 
Sbjct: 475 GPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQ--------PGPAKPSPQQPGS 526

Query: 585 QQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRP---KPQLAQKPS 641
            +   PP + PG A P+  A Q  P   +   +T+    +G G   +P    P   Q PS
Sbjct: 527 TK---PPSQQPGSAKPS--AQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPS 581

Query: 642 QDVP 645
           Q +P
Sbjct: 582 QGLP 585



 Score = 76.6 bits (187), Expect = 7e-14
 Identities = 70/227 (30%), Positives = 95/227 (41%), Gaps = 40/227 (17%)

Query: 415 AQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQP--AGPPAQQRPPPQGGPPQPG- 471
           AQ    ++     PG  +  Q P  G  P     +QQP  A PP QQ   P+    QPG 
Sbjct: 373 AQQTGSEKPSSEQPGPKALAQPPGVGKTP-----AQQPGPAKPPTQQVGTPKPLAQQPGL 427

Query: 472 ------PGP-----QRQGP---PLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQ 517
                 PGP     Q+ GP   P QQ  P +     +G   P     P +LP P   P Q
Sbjct: 428 QSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP-----PSQLPGPAKPPPQ 482

Query: 518 PASQAAPPTQGQGRQSRPVAGGPGA--PPAARP-PASPSPQRQAGPPQATRQTSVSGPAP 574
               A PP Q  G  ++P +  PG+  PP  +P PA PSPQ+       ++Q   + P+ 
Sbjct: 483 QPGPAKPPPQQPG-SAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSA 541

Query: 575 PKASGAPPGGQQR--------QGPPQKPPGPAGPTRQASQAGPVPRT 613
            + S A P  QQ          G P +PP  +   +Q    G +P+T
Sbjct: 542 QQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQG-LPKT 587



 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 75/253 (29%), Positives = 99/253 (39%), Gaps = 46/253 (18%)

Query: 455 PPAQQRPPPQGGPPQPGPGPQRQGP---PLQQRPPP-----QGQQHLSGLGPPAGSPL-- 504
           PP QQ+PP         P P++QGP   PLQQ   P     Q  + +    P  G P+  
Sbjct: 209 PPLQQQPPK--------PIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQG 260

Query: 505 PQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQAT 564
           P + P    A       A+ P   Q    R  +  P  P  ++PP               
Sbjct: 261 PTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPP--------------- 305

Query: 565 RQTSVSGPAPPKASGAPPGGQQRQGPPQKPPG-PAGPTRQ-ASQAGPV-PRTGPPTTQQP 621
               +  P P K     PG ++ Q  P KPP  P+G T+  A Q G V P   PP T +P
Sbjct: 306 ----IQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKP 361

Query: 622 RPSGPGPAGRPKPQL-AQKPSQDVPPPATAA----AGGPPHPQLNKSQSLTNAFNLPEPA 676
                GPA  P  Q  ++KPS + P P   A     G  P  Q   ++  T     P+P 
Sbjct: 362 PAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPL 421

Query: 677 PPRPSLSQDEVKA 689
             +P L Q   KA
Sbjct: 422 AQQPGL-QSPAKA 433



 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 76/286 (26%), Positives = 104/286 (36%), Gaps = 37/286 (12%)

Query: 421  QRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQG------GPPQPGPGP 474
            Q +   +P   +    PS    P G + S  P    A  RP          GP     G 
Sbjct: 786  QAEEKTTPPLKTDSAKPSQSFPPTGEKVS--PFDSKAIPRPASDSKIISHPGPSSESKG- 842

Query: 475  QRQGPPLQQRPPPQGQQHLSGLGP-----PAGSPLPQRLPSPTSAPQQPASQAAPPTQGQ 529
            Q+Q  P+Q++  P+  Q      P     P GSP P   P PT+    P  Q +P  Q Q
Sbjct: 843  QKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPG-PRPTAGQTVPTPQQSPKPQEQ 901

Query: 530  GRQSRPVAGGPGAPPAARPPASPSPQRQAGPP----------QATRQTSVSG-PAPPKAS 578
             R+     G     P ++P    +PQ                QA+   S +G P P   S
Sbjct: 902  SRRFSLNLGSITDAPKSQPT---TPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQS 958

Query: 579  GAPPGGQQRQGP-PQKPPGPAGPTRQASQAGPVPRTGPPT---TQQPRPSGPGPAGRPKP 634
            G  PG   +Q P P +PP   GP +   QA P P    P    T+ P      P     P
Sbjct: 959  G--PGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAP 1016

Query: 635  QLAQKPSQDVPPPATAAAGGPPHPQLNKSQSLTNAFNLPEPAPPRP 680
             + +  ++  PPP   +      PQ  K+   T     P+P    P
Sbjct: 1017 TVKRTETEKKPPPIKDSKSLTAEPQ--KAVLPTKLEKSPKPESTCP 1060



 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 78/302 (25%), Positives = 95/302 (31%), Gaps = 69/302 (22%)

Query: 416  QALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQ 475
            Q  P  +    SP   S    P P         S QP  PP    PPP   PP P     
Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPP----- 2423

Query: 476  RQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRP 535
                     PPP          PP  SP P  LP        P + A P           
Sbjct: 2424 ---------PPPL---------PPPTSPKPTILPKKKLTVASPVTTATPLFD-------- 2457

Query: 536  VAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGP-PQKP 594
                     A     + +  R  G P     T+   P PPK S  P G      P P KP
Sbjct: 2458 ---------AVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKP 2508

Query: 595  PGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKP-----QLAQKPSQDVPPPAT 649
            P    P         +P+  P TTQ+P    P P G          L       +P P +
Sbjct: 2509 PIAPKPV--------IPQL-PTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTS 2559

Query: 650  AAAGGPPHPQLNK-----SQSLTNAF---NLP-EPAPPRPSLSQDEVKAETIRSLRKSFA 700
                 P  P  NK     S+SLT  +    LP EP  P  S +   + +  + S  K   
Sbjct: 2560 -----PLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLV 2614

Query: 701  SL 702
            S+
Sbjct: 2615 SV 2616



 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 69/278 (24%), Positives = 94/278 (33%), Gaps = 30/278 (10%)

Query: 443 PLGRQTSQQPAGPPAQQ--RPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPA 500
           P  +QTS +    P Q   + P    PP     P   G P  +   P     LS   PP 
Sbjct: 677 PQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPK 736

Query: 501 GSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQA-- 558
              +P          +Q  +  A     Q +  +P      +  A   P  PS + Q+  
Sbjct: 737 EPSVPS---------EQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQA 787

Query: 559 ----GPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKP------PGPAGPTRQASQAG 608
                PP  T     S   PP      P   +    P         PGP+  ++   Q  
Sbjct: 788 EEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVD 847

Query: 609 PVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLN-KSQSLT 667
           PV +   P   Q + S P P  +P P    K S   P P   A    P PQ + K Q  +
Sbjct: 848 PVQKKEEPKKAQTKMS-PKPDAKPMP----KGSPTPPGPRPTAGQTVPTPQQSPKPQEQS 902

Query: 668 NAFNLPEPAPPRPSLSQDEVKAETIRSLRKSF-ASLFS 704
             F+L   +      SQ     ET+      F AS+FS
Sbjct: 903 RRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFS 940



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 66/256 (25%), Positives = 83/256 (32%), Gaps = 58/256 (22%)

Query: 419 PRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQ---PAGPPAQQRPPPQGGPPQPGPGPQ 475
           P Q+   A P     G T  P   P   + S Q   PA P AQQ   P     Q G G  
Sbjct: 510 PPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVS---QTGSGKP 566

Query: 476 RQGP---PLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQ--- 529
            Q P   P  ++PP QG        P    PL          P++         Q     
Sbjct: 567 LQPPTVSPSAKQPPSQGL-------PKTICPLCNTTELLLHVPEKANFNTCTECQTTVCS 619

Query: 530 -------------------GRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVS 570
                                Q +   GG  AP     P+SP P+ +  P   T   S S
Sbjct: 620 LCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPV----PSSPQPKLKTAPVTTTSAVSKS 675

Query: 571 GPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAG 630
            P P + S               P   A P +  S+A P P+  PP  +QP   G   A 
Sbjct: 676 SPQPQQTS---------------PKKDAAPKQDLSKA-PEPKKPPPLVKQPTLHGSPSAK 719

Query: 631 RPKPQLAQKPSQDVPP 646
             +P  A   S+  PP
Sbjct: 720 AKQPPEADSLSKPAPP 735



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 61/248 (24%), Positives = 82/248 (33%), Gaps = 69/248 (27%)

Query: 496 LGPPAGSPLPQRLPSPT--------SAPQQPASQAAPPTQGQGRQSRPVAGGPGAPP--A 545
           L P   SP P+   +P         S+PQ    Q +P      +Q    A  P  PP   
Sbjct: 650 LAPVPSSPQPKLKTAPVTTTSAVSKSSPQP--QQTSPKKDAAPKQDLSKAPEPKKPPPLV 707

Query: 546 ARPPASPSPQRQAG-PPQATRQTSVSGPAPPKASGAP------PGGQQRQGPPQ------ 592
            +P    SP  +A  PP+A    S+S PAPPK    P      P    +   P+      
Sbjct: 708 KQPTLHGSPSAKAKQPPEAD---SLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTT 764

Query: 593 ----------KPPGPAGPTRQASQAGPVP----------RTGPPTTQQ---------PRP 623
                     KP  P+   +  ++    P          ++ PPT ++         PRP
Sbjct: 765 DLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRP 824

Query: 624 -------SGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLNKSQSLTNAFNLPEPA 676
                  S PGP+   K Q    P Q    P  A     P P              P P 
Sbjct: 825 ASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPK-----GSPTPP 879

Query: 677 PPRPSLSQ 684
            PRP+  Q
Sbjct: 880 GPRPTAGQ 887



 Score = 31.6 bits (70), Expect = 2.6
 Identities = 25/87 (28%), Positives = 36/87 (41%), Gaps = 11/87 (12%)

Query: 509 PSPTSAPQQPASQAAPPTQGQGRQSRPVAG-GPGAPPAARPPASPSPQRQAGPPQATRQT 567
           PS T+ P    +  +  ++ + RQ   V     G P  + PPA+      A  P   R+ 
Sbjct: 32  PSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAA------AESPSMHRKQ 85

Query: 568 SVSGPAPPKASGAPPGGQQRQGPPQKP 594
            +    PPK SG PP      G P +P
Sbjct: 86  ELDSSHPPKQSGRPPD----PGRPAQP 108


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 99.0 bits (245), Expect = 1e-20
 Identities = 92/292 (31%), Positives = 118/292 (40%), Gaps = 45/292 (15%)

Query: 419 PRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQ--RPPPQGGPPQPGPGPQR 476
           P+ +Q D   G       PSP   P+ + T   P  PPAQQ      Q GP +P   P  
Sbjct: 281 PQTKQADIVRGESVKPSLPSPSKPPIQQPT---PGKPPAQQPGHEKSQPGPAKPPAQPSG 337

Query: 477 QGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPV 536
              PL Q+P         G   P   P     P  T  P QP   A PP Q  G + +P 
Sbjct: 338 LTKPLAQQP---------GTVKPPVQP-----PGTTKPPAQPLGPAKPPAQQTGSE-KPS 382

Query: 537 AGGPGAPPAARPP-ASPSPQRQAGPPQ-ATRQTSVSGP--------APPKASGAPPGGQQ 586
           +  PG    A+PP    +P +Q GP +  T+Q     P        +P KA G      Q
Sbjct: 383 SEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQ 442

Query: 587 RQGPPQKPPGPAGPTR-QASQAGPV-PRTGPPTTQQPRPSGPGPAGRPKPQL-------A 637
           + GP + P   AGP +  A Q GP  P +  P   +P P  PGPA +P PQ        +
Sbjct: 443 QPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPA-KPPPQQPGSAKPPS 501

Query: 638 QKPSQDVPPPAT--AAAGGPPHPQLNKSQSLTNAFNLP---EPAPPRPSLSQ 684
           Q+P    PPP     A   P  P   K  S       P   +P+P +PS  Q
Sbjct: 502 QQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQ 553



 Score = 97.1 bits (240), Expect = 5e-20
 Identities = 80/268 (29%), Positives = 102/268 (38%), Gaps = 22/268 (8%)

Query: 426 ASPGRGSHGQTPSPGALPLGRQ--TSQQPAGPPAQQRPPPQG-GPPQPGPGPQRQGPPLQ 482
           + PG       PS    PL +Q  T + P  PP   +PP Q  GP +P         P  
Sbjct: 324 SQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSS 383

Query: 483 QRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGA 542
           ++P P+         PP     P + P P   P Q      P  Q  G QS   A GP  
Sbjct: 384 EQPGPKALAQ-----PPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTK 438

Query: 543 PPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTR 602
            P  +P     P +QAGP + + Q +     P +  G      Q+ GP + PP   G  +
Sbjct: 439 TPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAK 498

Query: 603 QASQAGPVPRTGPPTTQQPRPSGPGP--AGRPKPQLAQ----KPSQDVPPPATAAAGGPP 656
             SQ    P +  P  QQP P+ P P   G  KP   Q    KPS   P PA      P 
Sbjct: 499 PPSQQ---PGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAK-----PS 550

Query: 657 HPQLNKSQSLTNAFNLPEPAPPRPSLSQ 684
             Q  K  S T +    +P    PS  Q
Sbjct: 551 AQQSTKPVSQTGSGKPLQPPTVSPSAKQ 578



 Score = 85.9 bits (211), Expect = 1e-16
 Identities = 77/244 (31%), Positives = 101/244 (41%), Gaps = 50/244 (20%)

Query: 436 TPSPGALPLG------------RQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQ 483
           T  P A PLG            + +S+QP GP A  +PP  G  P   PGP +  PP QQ
Sbjct: 358 TTKPPAQPLGPAKPPAQQTGSEKPSSEQP-GPKALAQPPGVGKTPAQQPGPAK--PPTQQ 414

Query: 484 RPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQ-PASQAAP-------------PTQGQ 529
              P+      GL  PA +P P + P     P + PA QA P             P+Q  
Sbjct: 415 VGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLP 474

Query: 530 G-RQSRPVAGGPGAPPAARPPASPSPQRQAG----PPQATRQTSVSGPAPPKASGAPPGG 584
           G  +  P   GP  PP  +P ++  P +Q G    PPQ         P P K S   PG 
Sbjct: 475 GPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQ--------PGPAKPSPQQPGS 526

Query: 585 QQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRP---KPQLAQKPS 641
            +   PP + PG A P+  A Q  P   +   +T+    +G G   +P    P   Q PS
Sbjct: 527 TK---PPSQQPGSAKPS--AQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPS 581

Query: 642 QDVP 645
           Q +P
Sbjct: 582 QGLP 585



 Score = 76.6 bits (187), Expect = 7e-14
 Identities = 70/227 (30%), Positives = 95/227 (41%), Gaps = 40/227 (17%)

Query: 415 AQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQP--AGPPAQQRPPPQGGPPQPG- 471
           AQ    ++     PG  +  Q P  G  P     +QQP  A PP QQ   P+    QPG 
Sbjct: 373 AQQTGSEKPSSEQPGPKALAQPPGVGKTP-----AQQPGPAKPPTQQVGTPKPLAQQPGL 427

Query: 472 ------PGP-----QRQGP---PLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQ 517
                 PGP     Q+ GP   P QQ  P +     +G   P     P +LP P   P Q
Sbjct: 428 QSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP-----PSQLPGPAKPPPQ 482

Query: 518 PASQAAPPTQGQGRQSRPVAGGPGA--PPAARP-PASPSPQRQAGPPQATRQTSVSGPAP 574
               A PP Q  G  ++P +  PG+  PP  +P PA PSPQ+       ++Q   + P+ 
Sbjct: 483 QPGPAKPPPQQPG-SAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSA 541

Query: 575 PKASGAPPGGQQR--------QGPPQKPPGPAGPTRQASQAGPVPRT 613
            + S A P  QQ          G P +PP  +   +Q    G +P+T
Sbjct: 542 QQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQG-LPKT 587



 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 75/253 (29%), Positives = 99/253 (39%), Gaps = 46/253 (18%)

Query: 455 PPAQQRPPPQGGPPQPGPGPQRQGP---PLQQRPPP-----QGQQHLSGLGPPAGSPL-- 504
           PP QQ+PP         P P++QGP   PLQQ   P     Q  + +    P  G P+  
Sbjct: 209 PPLQQQPPK--------PIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQG 260

Query: 505 PQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQAT 564
           P + P    A       A+ P   Q    R  +  P  P  ++PP               
Sbjct: 261 PTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPP--------------- 305

Query: 565 RQTSVSGPAPPKASGAPPGGQQRQGPPQKPPG-PAGPTRQ-ASQAGPV-PRTGPPTTQQP 621
               +  P P K     PG ++ Q  P KPP  P+G T+  A Q G V P   PP T +P
Sbjct: 306 ----IQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKP 361

Query: 622 RPSGPGPAGRPKPQL-AQKPSQDVPPPATAA----AGGPPHPQLNKSQSLTNAFNLPEPA 676
                GPA  P  Q  ++KPS + P P   A     G  P  Q   ++  T     P+P 
Sbjct: 362 PAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPL 421

Query: 677 PPRPSLSQDEVKA 689
             +P L Q   KA
Sbjct: 422 AQQPGL-QSPAKA 433



 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 76/286 (26%), Positives = 104/286 (36%), Gaps = 37/286 (12%)

Query: 421  QRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQG------GPPQPGPGP 474
            Q +   +P   +    PS    P G + S  P    A  RP          GP     G 
Sbjct: 786  QAEEKTTPPLKTDSAKPSQSFPPTGEKVS--PFDSKAIPRPASDSKIISHPGPSSESKG- 842

Query: 475  QRQGPPLQQRPPPQGQQHLSGLGP-----PAGSPLPQRLPSPTSAPQQPASQAAPPTQGQ 529
            Q+Q  P+Q++  P+  Q      P     P GSP P   P PT+    P  Q +P  Q Q
Sbjct: 843  QKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPG-PRPTAGQTVPTPQQSPKPQEQ 901

Query: 530  GRQSRPVAGGPGAPPAARPPASPSPQRQAGPP----------QATRQTSVSG-PAPPKAS 578
             R+     G     P ++P    +PQ                QA+   S +G P P   S
Sbjct: 902  SRRFSLNLGSITDAPKSQPT---TPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQS 958

Query: 579  GAPPGGQQRQGP-PQKPPGPAGPTRQASQAGPVPRTGPPT---TQQPRPSGPGPAGRPKP 634
            G  PG   +Q P P +PP   GP +   QA P P    P    T+ P      P     P
Sbjct: 959  G--PGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAP 1016

Query: 635  QLAQKPSQDVPPPATAAAGGPPHPQLNKSQSLTNAFNLPEPAPPRP 680
             + +  ++  PPP   +      PQ  K+   T     P+P    P
Sbjct: 1017 TVKRTETEKKPPPIKDSKSLTAEPQ--KAVLPTKLEKSPKPESTCP 1060



 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 78/302 (25%), Positives = 95/302 (31%), Gaps = 69/302 (22%)

Query: 416  QALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQ 475
            Q  P  +    SP   S    P P         S QP  PP    PPP   PP P     
Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPP----- 2423

Query: 476  RQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRP 535
                     PPP          PP  SP P  LP        P + A P           
Sbjct: 2424 ---------PPPL---------PPPTSPKPTILPKKKLTVASPVTTATPLFD-------- 2457

Query: 536  VAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGP-PQKP 594
                     A     + +  R  G P     T+   P PPK S  P G      P P KP
Sbjct: 2458 ---------AVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKP 2508

Query: 595  PGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKP-----QLAQKPSQDVPPPAT 649
            P    P         +P+  P TTQ+P    P P G          L       +P P +
Sbjct: 2509 PIAPKPV--------IPQL-PTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTS 2559

Query: 650  AAAGGPPHPQLNK-----SQSLTNAF---NLP-EPAPPRPSLSQDEVKAETIRSLRKSFA 700
                 P  P  NK     S+SLT  +    LP EP  P  S +   + +  + S  K   
Sbjct: 2560 -----PLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLV 2614

Query: 701  SL 702
            S+
Sbjct: 2615 SV 2616



 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 69/278 (24%), Positives = 94/278 (33%), Gaps = 30/278 (10%)

Query: 443 PLGRQTSQQPAGPPAQQ--RPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPA 500
           P  +QTS +    P Q   + P    PP     P   G P  +   P     LS   PP 
Sbjct: 677 PQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPK 736

Query: 501 GSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQA-- 558
              +P          +Q  +  A     Q +  +P      +  A   P  PS + Q+  
Sbjct: 737 EPSVPS---------EQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQA 787

Query: 559 ----GPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKP------PGPAGPTRQASQAG 608
                PP  T     S   PP      P   +    P         PGP+  ++   Q  
Sbjct: 788 EEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVD 847

Query: 609 PVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLN-KSQSLT 667
           PV +   P   Q + S P P  +P P    K S   P P   A    P PQ + K Q  +
Sbjct: 848 PVQKKEEPKKAQTKMS-PKPDAKPMP----KGSPTPPGPRPTAGQTVPTPQQSPKPQEQS 902

Query: 668 NAFNLPEPAPPRPSLSQDEVKAETIRSLRKSF-ASLFS 704
             F+L   +      SQ     ET+      F AS+FS
Sbjct: 903 RRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFS 940



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 66/256 (25%), Positives = 83/256 (32%), Gaps = 58/256 (22%)

Query: 419 PRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQ---PAGPPAQQRPPPQGGPPQPGPGPQ 475
           P Q+   A P     G T  P   P   + S Q   PA P AQQ   P     Q G G  
Sbjct: 510 PPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVS---QTGSGKP 566

Query: 476 RQGP---PLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQ--- 529
            Q P   P  ++PP QG        P    PL          P++         Q     
Sbjct: 567 LQPPTVSPSAKQPPSQGL-------PKTICPLCNTTELLLHVPEKANFNTCTECQTTVCS 619

Query: 530 -------------------GRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVS 570
                                Q +   GG  AP     P+SP P+ +  P   T   S S
Sbjct: 620 LCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPV----PSSPQPKLKTAPVTTTSAVSKS 675

Query: 571 GPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAG 630
            P P + S               P   A P +  S+A P P+  PP  +QP   G   A 
Sbjct: 676 SPQPQQTS---------------PKKDAAPKQDLSKA-PEPKKPPPLVKQPTLHGSPSAK 719

Query: 631 RPKPQLAQKPSQDVPP 646
             +P  A   S+  PP
Sbjct: 720 AKQPPEADSLSKPAPP 735



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 61/248 (24%), Positives = 82/248 (33%), Gaps = 69/248 (27%)

Query: 496 LGPPAGSPLPQRLPSPT--------SAPQQPASQAAPPTQGQGRQSRPVAGGPGAPP--A 545
           L P   SP P+   +P         S+PQ    Q +P      +Q    A  P  PP   
Sbjct: 650 LAPVPSSPQPKLKTAPVTTTSAVSKSSPQP--QQTSPKKDAAPKQDLSKAPEPKKPPPLV 707

Query: 546 ARPPASPSPQRQAG-PPQATRQTSVSGPAPPKASGAP------PGGQQRQGPPQ------ 592
            +P    SP  +A  PP+A    S+S PAPPK    P      P    +   P+      
Sbjct: 708 KQPTLHGSPSAKAKQPPEAD---SLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTT 764

Query: 593 ----------KPPGPAGPTRQASQAGPVP----------RTGPPTTQQ---------PRP 623
                     KP  P+   +  ++    P          ++ PPT ++         PRP
Sbjct: 765 DLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRP 824

Query: 624 -------SGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLNKSQSLTNAFNLPEPA 676
                  S PGP+   K Q    P Q    P  A     P P              P P 
Sbjct: 825 ASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPK-----GSPTPP 879

Query: 677 PPRPSLSQ 684
            PRP+  Q
Sbjct: 880 GPRPTAGQ 887



 Score = 31.6 bits (70), Expect = 2.6
 Identities = 25/87 (28%), Positives = 36/87 (41%), Gaps = 11/87 (12%)

Query: 509 PSPTSAPQQPASQAAPPTQGQGRQSRPVAG-GPGAPPAARPPASPSPQRQAGPPQATRQT 567
           PS T+ P    +  +  ++ + RQ   V     G P  + PPA+      A  P   R+ 
Sbjct: 32  PSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAA------AESPSMHRKQ 85

Query: 568 SVSGPAPPKASGAPPGGQQRQGPPQKP 594
            +    PPK SG PP      G P +P
Sbjct: 86  ELDSSHPPKQSGRPPD----PGRPAQP 108


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 95.5 bits (236), Expect = 1e-19
 Identities = 75/215 (34%), Positives = 82/215 (38%), Gaps = 29/215 (13%)

Query: 460 RPPPQG-------GPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPT 512
           R PP G       GP  PGPG     PP+   PP Q QQ      PP   P PQ+ P   
Sbjct: 32  RSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQ-----PPPQQPPPQQPPPHQ 86

Query: 513 SAPQ-QPASQAAPPTQGQGRQSRPVAGGPGAPPA--ARPPASPSPQRQAGPPQATRQTSV 569
             P  QP  Q  PP   Q      VA GPG  P   + PPAS S      P       S 
Sbjct: 87  PPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSG 146

Query: 570 SGPAP---PKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPS-G 625
            GP P   P  + APPG      PP  PP    PT      GP P         P P  G
Sbjct: 147 PGPTPTPPPAVTSAPPGA-----PPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQG 201

Query: 626 PGPAGRPKPQLAQKPSQDVP--PPATAAAGGPPHP 658
           PGP G   P+  + P    P   P  +  GG P P
Sbjct: 202 PGPGG---PKGGKMPGGPKPGGGPGLSTPGGHPKP 233



 Score = 93.2 bits (230), Expect = 7e-19
 Identities = 82/245 (33%), Positives = 94/245 (38%), Gaps = 47/245 (19%)

Query: 421 QRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPP 480
           Q +    PG G  G  P     P  +Q  Q P   P  Q+PPP   PP P P  Q+Q PP
Sbjct: 42  QNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPP 101

Query: 481 LQQRPPP----QGQQHLSGLG--PPAGSPLPQRLPSPTSAPQ----------QPASQAAP 524
             Q        QG     G+G  PPA S  P   P  + AP            PA  +AP
Sbjct: 102 PPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAP 161

Query: 525 P-------TQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKA 577
           P              + P AGGP  PPAA P   P P++  GP          GP   K 
Sbjct: 162 PGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGP---------GGPKGGKM 212

Query: 578 SGAP-PGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTG----PPTTQQ----PRPSGPGP 628
            G P PGG    GP    PG  G  +   + G  PR G    PP  QQ    P P GPG 
Sbjct: 213 PGGPKPGG----GPGLSTPG--GHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGPGG 266

Query: 629 AGRPK 633
               K
Sbjct: 267 RSEEK 271



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 55/168 (32%), Positives = 62/168 (36%), Gaps = 27/168 (16%)

Query: 528 GQGRQSRPVAGGPGAPPAAR-PPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQ 586
           G G   R   GG G     R PP      +  GP         SGP PP     PP  QQ
Sbjct: 13  GGGFHRRGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPG--PGQSGPKPP-IPPPPPHQQQ 69

Query: 587 RQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRP-----------SGPGPAGRPKPQ 635
           +Q PPQ+PP    P  Q     P P   P   QQP P            GPGPA  P   
Sbjct: 70  QQPPPQQPPPQQPPPHQ-----PPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPA--PGVG 122

Query: 636 LAQKPSQDVPPPATAAAGGP----PHPQLNKSQSLTNA-FNLPEPAPP 678
            A   S   PP     +G P    P P      ++T+A    P P PP
Sbjct: 123 SAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPP 170



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 22/54 (40%), Positives = 29/54 (53%), Gaps = 6/54 (11%)

Query: 26  QRPQPPPPPPGAHSP----GATPGPGTATAERSSGVAPAASPAAPSPGSSGGGG 75
           Q+ QPPPPP  +  P    G  P PG  +A  +S  AP A+P  P+ G+  G G
Sbjct: 95  QQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATP--PTSGAPPGSG 146



 Score = 38.1 bits (87), Expect = 0.028
 Identities = 34/115 (29%), Positives = 42/115 (36%), Gaps = 24/115 (20%)

Query: 576 KASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKP- 634
           ++ G   GG  R+G      G  G         P P  G    + P   GPG +G PKP 
Sbjct: 7   RSRGGGGGGFHRRG------GGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSG-PKPP 59

Query: 635 --------QLAQKPSQDVPPPATAAAGGPPHPQLNKSQSLTNAFNLPEPAPPRPS 681
                   Q  Q P Q  PP        PPHPQ ++ Q          P PP+ S
Sbjct: 60  IPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQ--------PPPPPQDS 106



 Score = 33.5 bits (75), Expect = 0.69
 Identities = 18/53 (33%), Positives = 18/53 (33%)

Query: 23  TDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGGG 75
           T  Q   PPPPP     PG  P  G        G  P        PG S  GG
Sbjct: 177 TPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGG 229



 Score = 31.2 bits (69), Expect = 3.4
 Identities = 21/66 (31%), Positives = 24/66 (36%), Gaps = 20/66 (30%)

Query: 28  PQPPPPPPGAH-------------------SPGATPGPGTATAERSSGVAPAASPAAPSP 68
           P  PPP P  H                    PG  PG G+A    SS   PA  P + +P
Sbjct: 84  PHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSA-PPASSSAPPATPPTSGAP 142

Query: 69  GSSGGG 74
             SG G
Sbjct: 143 PGSGPG 148



 Score = 31.2 bits (69), Expect = 3.4
 Identities = 16/43 (37%), Positives = 19/43 (44%), Gaps = 2/43 (4%)

Query: 30  PPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSG 72
           P  PP     PG+ PGP        +   P A P  P+P SSG
Sbjct: 133 PATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPP--PTPPSSG 173



 Score = 30.4 bits (67), Expect = 5.9
 Identities = 16/47 (34%), Positives = 18/47 (38%), Gaps = 5/47 (10%)

Query: 28  PQPPPPPPGAHSPGATPGP-----GTATAERSSGVAPAASPAAPSPG 69
           P P PPP    +P   P P     G  T    +G  P    A P PG
Sbjct: 149 PTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPG 195


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 95.5 bits (236), Expect = 1e-19
 Identities = 81/290 (27%), Positives = 124/290 (42%), Gaps = 50/290 (17%)

Query: 412 NKMAQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQR---PPPQGGPP 468
           ++ A   PR+RQ++ SP RG   ++PSP   P  R+ S  PA PP ++R   PPP+   P
Sbjct: 526 SRSASPSPRKRQKETSP-RGRRRRSPSPP--PTRRRRSPSPAPPPRRRRTPTPPPRRRTP 582

Query: 469 QP-----GPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAA 523
            P      P P+R  PP+Q+R  P              SP P+R    T++P  P  + A
Sbjct: 583 SPPPRRRSPSPRRYSPPIQRRYSP--------------SPPPKRR---TASPPPPPKRRA 625

Query: 524 PPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPG 583
            P+                PP  R   SP P++++ P    R  S+S      +S +   
Sbjct: 626 SPSP---------------PPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRST 670

Query: 584 GQQRQGPPQK--PPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPS 641
            + R   P K   P P     Q S + P  R G  ++ Q R S P P+ RP  ++++ P 
Sbjct: 671 REARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQS-PSPSTRPIRRVSRTPE 729

Query: 642 QDVPPPATAAAGGPPHPQLNKSQSLTNAFNLPEPAPPRPSLSQDEVKAET 691
               P     A  P    + +  S  +    PEPA  +P      V++++
Sbjct: 730 ----PKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQS 775



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 57/237 (24%), Positives = 81/237 (34%), Gaps = 65/237 (27%)

Query: 419 PRQRQRDASPGRGS----HGQTPSPGALPLGRQTSQQPAGPP--AQQRPPPQGGPPQPGP 472
           P  R+R  SP R S       +PSP   P  R+T+  P  P   A   PPP+       P
Sbjct: 584 PPPRRRSPSPRRYSPPIQRRYSPSP---PPKRRTASPPPPPKRRASPSPPPKRRVSHSPP 640

Query: 473 GPQRQGPPLQQRPPPQGQQHLSGLGPP-----AGSPLPQRLPSPTSAPQQPASQAAPPTQ 527
             QR  P  ++R P    +H  G  P      A SP P +  SP+  P+ P + ++PP  
Sbjct: 641 PKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPV 700

Query: 528 GQGRQS---------------------------------------------------RPV 536
            +G  S                                                    P 
Sbjct: 701 RRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPA 760

Query: 537 AGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQK 593
           A  P APP+     SPS       P    ++    P+PP+ S    GG++++    K
Sbjct: 761 AKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDK 817



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 60/285 (21%), Positives = 105/285 (36%), Gaps = 29/285 (10%)

Query: 420 RQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGP--------PQPG 471
           R+R    SP   +  ++PSP A     +T + P      + P  Q           P+P 
Sbjct: 193 RKRSHSRSPRHRTKSRSPSP-APEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPE 251

Query: 472 PGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGR 531
           P P+ + P  ++    + ++  +     + S    R  S + +  +P  +    ++    
Sbjct: 252 PIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSP 311

Query: 532 QSRPVAGGPGAP----PAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQR 587
           + RP      +P    P  R P  P  +R   P +  R++S S      +S +       
Sbjct: 312 RRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPP 371

Query: 588 QGPPQKPPGPAGPTRQASQAGPVP----RTGPPTTQQPRPSGPGPAGRPKPQLAQ--KPS 641
           + PP++   P   TR+ S +   P    R  PP T  P+         P PQ +   + S
Sbjct: 372 KKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPK-----TRHSPTPQQSNRTRKS 426

Query: 642 QDVPPPATAAAGGPPHPQLNKSQSLTNAFNLPEPAPPRPSLSQDE 686
           +    P   +     H    K +S +     P P P +  LS+ E
Sbjct: 427 RVSVSPGRTSGKVTKHKGTEKRESPS-----PAPKPRKVELSESE 466



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 60/306 (19%), Positives = 98/306 (32%), Gaps = 47/306 (15%)

Query: 419 PRQRQRDASPG----RGSHGQTPSPGALPLGRQTSQQP---AGPPAQQRPPPQGGPPQPG 471
           PR+R R + P     +  H  TP         + S  P   +G   + +   +   P P 
Sbjct: 395 PRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPA 454

Query: 472 PGPQR---------------QGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQ 516
           P P++                   +QQR   + Q   S     + S      P  +    
Sbjct: 455 PKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKN 514

Query: 517 ---------QPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQT 567
                     P+  A+P  + + +++ P           R P+ P  +R+  P  A    
Sbjct: 515 GEVGRRRRHSPSRSASPSPRKRQKETSPRGR------RRRSPSPPPTRRRRSPSPAPPPR 568

Query: 568 SVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPG 627
               P PP     P    +R+ P  +   P    R +    P  RT  P     R + P 
Sbjct: 569 RRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPS 628

Query: 628 PAGR------PKPQLAQKPSQDVPPPATAA---AGGPPHPQLNKSQS-LTNAFNLPEPAP 677
           P  +      P P+    P      P+ ++    G  P     +++S   N  + P P P
Sbjct: 629 PPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRP 688

Query: 678 PRPSLS 683
             P  S
Sbjct: 689 RAPQTS 694



 Score = 31.6 bits (70), Expect = 2.6
 Identities = 20/70 (28%), Positives = 28/70 (40%), Gaps = 6/70 (8%)

Query: 6   RRLSDSNFMANLPNGYMTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAA 65
           RR+S S  ++  P       ++P  PP P  + SP     P     +  S   P  SP+ 
Sbjct: 745 RRVSSSRSVSGSPE---PAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKS---PTPSPSP 798

Query: 66  PSPGSSGGGG 75
           P      GGG
Sbjct: 799 PRNSDQEGGG 808



 Score = 30.8 bits (68), Expect = 4.5
 Identities = 41/187 (21%), Positives = 61/187 (32%), Gaps = 61/187 (32%)

Query: 544 PAARPPASPSPQRQAGPPQATRQTSVS------------GPAPPKASGAP---------- 581
           P  R   SPSP+R++ P +  R+ S S             PAP K    P          
Sbjct: 172 PRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVK 231

Query: 582 -PGGQQ--------RQGPPQKPPGPAGP------------------TRQASQAGPVPRTG 614
            P  Q+        +   P+  P P  P                  +R  S++    R+ 
Sbjct: 232 EPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSR 291

Query: 615 PPTTQQPR------------PSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLNK 662
            P+  +PR               P P  RP P+    P +  PPP    +  P   +   
Sbjct: 292 SPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRS 351

Query: 663 SQSLTNA 669
           S SL+ +
Sbjct: 352 SASLSGS 358


>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
          Length = 1336

 Score = 95.5 bits (236), Expect = 1e-19
 Identities = 103/345 (29%), Positives = 128/345 (37%), Gaps = 57/345 (16%)

Query: 399 QDEDKQLIVELVVNKMAQALPRQRQRDASPGRGSHGQTPSPGALPLGR--QTSQQPAGPP 456
           Q  + QL+ +L + ++AQ    Q Q   S G    G  P PG  P+ +  Q  QQP   P
Sbjct: 549 QYTNPQLLEQLKIERLAQKQVEQIQPPPSSGTPLLGPQPFPGQGPMSQIPQGFQQP--HP 606

Query: 457 AQQRP--PPQGGPPQP-----GPGPQ----RQGPPLQQ-RPPPQGQQHLSG-LGPPAGSP 503
           +QQ P    Q GPP P      PGPQ     QGPPL Q    PQG     G  GPP G P
Sbjct: 607 SQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLP 666

Query: 504 LPQRLPSPTSAPQQPASQAAPPTQG----QGRQSRPVAGGPGAPPAAR----PPASPSPQ 555
            PQ +  P    + P        QG    QG        GP  PP  +    P   P PQ
Sbjct: 667 RPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQ 726

Query: 556 RQAGPPQATRQTSVSGPAPPKASGAP---------PGGQQRQGPPQK-------PPGPAG 599
              GP        + GP  P+    P         PG Q  QGP  +       P G  G
Sbjct: 727 GHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQG 786

Query: 600 PTRQASQAGPVPR---TGPPTTQQPRPSGPGPAGRPKPQLAQKPSQ----DVPPPATAAA 652
           P       GP P+    G P  +   P  PG      PQ  + P +      PPP  +  
Sbjct: 787 PPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSML 846

Query: 653 G------GPPHPQLNKSQSLTNAFNLPE---PAPPRPSLSQDEVK 688
           G      GPP  Q  +     +    P+     PP P   Q+  +
Sbjct: 847 GPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPAR 891



 Score = 87.4 bits (215), Expect = 4e-17
 Identities = 100/297 (33%), Positives = 114/297 (38%), Gaps = 59/297 (19%)

Query: 416 QALPRQRQRDASPGR----GSHGQTPSPGALPLGRQTSQQPAGPPAQQRPP-PQGG-PPQ 469
           Q LPR +      G     G HG     G  P G Q S  P G    Q PP PQG   PQ
Sbjct: 663 QGLPRPQDMHGPQGMQRHPGPHGPLGPQG--PPGPQGSSGPQGHMGPQGPPGPQGHIGPQ 720

Query: 470 PGPGPQR----QGPP----LQQRPPPQGQQ---HLSGL----------GPPAGSPLPQRL 508
             PGPQ     QGPP    +Q  P P+G Q   H  G+          GP +  PL    
Sbjct: 721 GPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLN 780

Query: 509 PSPTSAPQQPASQAAPPTQGQ--GRQSRPVAGG--PGAPPAARPPASPSPQRQAGPPQAT 564
           P     P  P     P  QG   G   + + G   PG      P     PQ   G     
Sbjct: 781 PRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPP 840

Query: 565 RQTSVSGPAPPKASGAPPGGQQRQGPPQ----KPP-----GPAGPTRQASQA-GPVPRTG 614
            Q S+ GP  P+    PPG Q +QGPPQ     PP     GP GP  Q + A GP P  G
Sbjct: 841 PQGSMLGP--PQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQG 898

Query: 615 P-PTTQQPRP-SGPGP----------AGRPK--PQLAQKPSQDVPPPATAAAGGPPH 657
           P P  QQ  P  G GP           G P   P L Q+ +Q   PP     G  P+
Sbjct: 899 PIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPN 955



 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 77/242 (31%), Positives = 90/242 (37%), Gaps = 29/242 (11%)

Query: 416 QALPRQRQRDASPG----RGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQG----GP 467
           Q  P        PG    +G   Q P  G  P G Q    P GP   Q P PQG     P
Sbjct: 750 QGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQG---PPGPRENQGPAPQGMIMGHP 806

Query: 468 PQPGPGPQRQGPPLQQRPPP-QGQQHLSGLG--PPAGSPL--PQRLPSPTSAPQQ---PA 519
           PQ   GP   G  L   P   +G Q + G+   PP GS L  PQ L  P  +  Q   P 
Sbjct: 807 PQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQ 866

Query: 520 SQAAPPTQGQGRQSRPVAGGPGAPPAA-RPPASPSPQRQA-------GPPQATRQTSVSG 571
               PP QG G Q  P   G   P     P   P P +Q        GP     Q   S 
Sbjct: 867 GSLGPPPQG-GMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQST 925

Query: 572 PAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGR 631
             PP   G    G Q + PP  P    GP +  S+  P    GP + ++   SG GP   
Sbjct: 926 GPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSG-GPEHG 984

Query: 632 PK 633
           P+
Sbjct: 985 PE 986



 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 85/289 (29%), Positives = 103/289 (35%), Gaps = 55/289 (19%)

Query: 419  PRQRQRDASPG----------RGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQG--- 465
            PR+ Q  A  G          RG H   P  G L  G Q  + P      Q PPPQG   
Sbjct: 790  PRENQGPAPQGMIMGHPPQEMRGPH---PPGGLLGHGPQEMRGPQEIRGMQGPPPQGSML 846

Query: 466  GPPQPGPGP----QRQGPP-----------LQQRPPPQGQQHLSGLGPPAGSPLP---QR 507
            GPPQ   GP     +QGPP           +Q  P PQGQQ+ +    P+  P+P   Q+
Sbjct: 847  GPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQK 906

Query: 508  LPSPTSAPQQPASQAA---------PPTQGQGRQSR--PVAGGPGAPPAARPPASPSPQR 556
             P     P+ P +Q           P    QG Q R  P+  G G  P       P P  
Sbjct: 907  TPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGP-PNH 965

Query: 557  QAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPP-QKPPGPAGPT--RQASQAGPVPRT 613
              GP    R     GP      G   GGQ  +GPP ++ P P  P    +     P  R 
Sbjct: 966  HMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRF 1025

Query: 614  GPPTTQQPRPSGPGP------AGRPKPQLAQKPSQDVPPPATAAAGGPP 656
            G    +     GP P       G P P       +        AA GPP
Sbjct: 1026 GHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPP 1074



 Score = 36.6 bits (83), Expect = 0.082
 Identities = 37/158 (23%), Positives = 56/158 (35%), Gaps = 24/158 (15%)

Query: 380  GRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMAQALPRQRQRDASPGRGSHGQTPSP 439
            G +H  +      P    H    ++    L    MA   PR+R     PG   H +  +P
Sbjct: 1191 GHEHFRDTPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAP 1250

Query: 440  GALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQH-----LS 494
            G               P++ R    GG  + GPGP ++ P   +     G+ H       
Sbjct: 1251 GG--------------PSEDR----GGKGRGGPGPAQRVPKSGRSSSLDGEHHDGYHRDE 1292

Query: 495  GLGPPAGSPLPQR-LPSPTSAPQQPASQAAPPTQGQGR 531
              G P GS  P R   S ++  +     + PP +G  R
Sbjct: 1293 PFGGPPGSGTPSRGGRSGSNWGRGSNMNSGPPRRGASR 1330



 Score = 33.5 bits (75), Expect = 0.69
 Identities = 41/195 (21%), Positives = 63/195 (32%), Gaps = 47/195 (24%)

Query: 427  SPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPG-------PQRQGP 479
            +P  G  G  P+P   P               ++P    G  +PGPG       P+   P
Sbjct: 1155 TPRGGRKGLLPTPDEFPRFE----------GGRKPDSWDGNREPGPGHEHFRDTPRPDHP 1204

Query: 480  PLQQRPPPQGQQHLSGLGPPAGSPLPQRLP---SPTSAPQQPASQAAPPTQGQGRQSRPV 536
            P     P   ++  S  G    S  P++ P    P ++  +       P++ +G + R  
Sbjct: 1205 PHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGR-- 1262

Query: 537  AGGPGAP------------------------PAARPPASPSPQRQAGPPQATRQTSVSGP 572
             GGPG                          P   PP S +P R         + S    
Sbjct: 1263 -GGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNWGRGSNMNS 1321

Query: 573  APPKASGAPPGGQQR 587
             PP+   +  GG+ R
Sbjct: 1322 GPPRRGASRGGGRGR 1336



 Score = 32.0 bits (71), Expect = 2.0
 Identities = 48/188 (25%), Positives = 67/188 (35%), Gaps = 20/188 (10%)

Query: 446  RQTSQQPAGPPAQQ-RPPPQGGPPQPGP---GPQRQGPPLQQRPPPQGQQHLSGLGPPAG 501
            R+ S +   PP  + R PP+G    PGP   GP+      ++    +  +   G G P G
Sbjct: 1100 REESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAARGRDLRG-RGRGTPRG 1158

Query: 502  SPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPP 561
                  LP+P   P+    +   P    G +      GPG       P    P      P
Sbjct: 1159 G-RKGLLPTPDEFPRFEGGR--KPDSWDGNRE----PGPGHEHFRDTPRPDHPPHDGHSP 1211

Query: 562  QATRQTSVSGPAPPKASGAPPGGQQRQGP----PQKPPGPAGPTRQASQAGPVPRTGPPT 617
             A+R+ S S      AS  P       GP     ++   P GP+      G   R GP  
Sbjct: 1212 -ASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKG---RGGPGP 1267

Query: 618  TQQPRPSG 625
             Q+   SG
Sbjct: 1268 AQRVPKSG 1275


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 89.4 bits (220), Expect = 1e-17
 Identities = 81/241 (33%), Positives = 92/241 (38%), Gaps = 44/241 (18%)

Query: 419 PRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQG 478
           P    R A P +G  G+   PGA+P G      PAGP         GGPP P P  Q   
Sbjct: 189 PGGSSRAAFP-QGGRGRGRFPGAVP-GGDRFPGPAGP---------GGPPPPFPAGQTPP 237

Query: 479 -PPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVA 537
            PPL    PP         GPP   P  Q LP P + P     +  PP    G+      
Sbjct: 238 RPPLGPPGPP---------GPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPF---- 284

Query: 538 GGPGAPP-AARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPG 596
              G PP    PP  P P    GPP         GP PP+    PP G      P +PPG
Sbjct: 285 ---GQPPLGPLPPGPPPPVPGYGPP--------PGPPPPQQGPPPPPGPF----PPRPPG 329

Query: 597 PAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDV-PPPATAAAGGP 655
           P GP    + A P    GPP    P      PA  P P  +  P+ D   PP T   G P
Sbjct: 330 PLGP--PLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRP 387

Query: 656 P 656
           P
Sbjct: 388 P 388



 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 67/200 (33%), Positives = 73/200 (36%), Gaps = 31/200 (15%)

Query: 425 DASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGP--GPQRQGPPLQ 482
           D  PG    G  P P   P G+   + P GPP    PP   GPP PG    P   GPP +
Sbjct: 215 DRFPGPAGPGGPPPP--FPAGQTPPRPPLGPPGPPGPP---GPPPPGQVLPPPLAGPPNR 269

Query: 483 -QRPPPQ--------GQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQS 533
             RPPP         GQ  L  L P    P+P   P P   P Q   Q  PP  G     
Sbjct: 270 GDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQ---QGPPPPPGPFPPR 326

Query: 534 RPVAGGPGAPPA--ARPPASPSPQRQAGPPQATRQTSVSGPA--PPKASGAPPGGQQRQG 589
            P   GP  PP   A PP  P P     PP A        PA  PP  +   P    R  
Sbjct: 327 PP---GPLGPPLTLAPPPHLPGP-----PPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGP 378

Query: 590 PPQKPPGPAGPTRQASQAGP 609
           PP  P G   P  +     P
Sbjct: 379 PPTDPYGRPPPYDRGDYGPP 398



 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 51/136 (37%), Positives = 56/136 (41%), Gaps = 21/136 (15%)

Query: 437 PSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQ----GPPLQQRPPPQGQQH 492
           P  G LP G        GPP    PP QG PP PGP P R     GPPL   PPP    H
Sbjct: 287 PPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPP----H 342

Query: 493 LSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASP 552
           L   GPP G+P P    +P   P        PPT   G  +    G P   P  RPP  P
Sbjct: 343 LP--GPPPGAPPPAPHVNPAFFP--------PPT-NSGMPTSDSRGPPPTDPYGRPP--P 389

Query: 553 SPQRQAGPPQATRQTS 568
             +   GPP     T+
Sbjct: 390 YDRGDYGPPGREMDTA 405



 Score = 63.5 bits (153), Expect = 6e-10
 Identities = 78/259 (30%), Positives = 85/259 (32%), Gaps = 52/259 (20%)

Query: 425 DASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPP--LQ 482
           D  P R  HGQ P     P  +Q   Q      Q R   Q G      G  + GPP    
Sbjct: 142 DLLPKRELHGQNPV--VTPCNKQFLSQFE---MQSRKTTQSGQMS---GEGKAGPPGGSS 193

Query: 483 QRPPPQGQQHLSGLGP-PAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPG 541
           +   PQG +   G G  P   P   R P P      P     PP        RP  G PG
Sbjct: 194 RAAFPQGGR---GRGRFPGAVPGGDRFPGPAGPGGPP-----PPFPAGQTPPRPPLGPPG 245

Query: 542 APPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPT 601
            P    PP  P P +   PP A        P PP      P GQ   GP   PPGP  P 
Sbjct: 246 PPG---PPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGP--LPPGPPPP- 299

Query: 602 RQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLN 661
                   VP  GPP         PGP           P Q  PPP        P   L 
Sbjct: 300 --------VPGYGPP---------PGPP----------PPQQGPPPPPGPFPPRPPGPLG 332

Query: 662 KSQSLTNAFNLPEPAPPRP 680
              +L    +LP P P  P
Sbjct: 333 PPLTLAPPPHLPGPPPGAP 351



 Score = 32.0 bits (71), Expect = 2.0
 Identities = 20/62 (32%), Positives = 23/62 (37%), Gaps = 1/62 (1%)

Query: 28  PQPPPPPPGAHSPGATPGP-GTATAERSSGVAPAASPAAPSPGSSGGGGFFSSLSNAVKQ 86
           PQ  PPPP    P   PGP G           P   P AP P       FF   +N+   
Sbjct: 312 PQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMP 371

Query: 87  TT 88
           T+
Sbjct: 372 TS 373


>gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2
           preproprotein [Homo sapiens]
          Length = 198

 Score = 89.4 bits (220), Expect = 1e-17
 Identities = 69/185 (37%), Positives = 78/185 (42%), Gaps = 25/185 (13%)

Query: 452 PAGPPAQQRPPPQGGPPQPGP--GPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLP 509
           P GP  Q    PQG PP PG   GP  QG    Q PPP G+      GPP   P   +  
Sbjct: 36  PQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ----GPP---PQGDKSR 88

Query: 510 SPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSV 569
           SP S P +P     PP QG   Q  P  GG       +P   P P +  GPP      S 
Sbjct: 89  SPRSPPGKPQG---PPPQGGKPQGPPPQGGN------KPQGPPPPGKPQGPPAQGGSKSQ 139

Query: 570 SGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRT-GPPTTQQPRPSGPGP 628
           S  +PP     PP  QQ    PQ PP PAG   Q  QA P  +  GPP      P G  P
Sbjct: 140 SARSPPGKPQGPP--QQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRP----PQGGRP 193

Query: 629 AGRPK 633
           +  P+
Sbjct: 194 SRPPQ 198



 Score = 86.7 bits (213), Expect = 7e-17
 Identities = 70/180 (38%), Positives = 76/180 (42%), Gaps = 22/180 (12%)

Query: 453 AGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPA--GSPLPQ--RL 508
           AG P  Q P PQGG    GP P    P   Q PPPQG     G  PP     P PQ  + 
Sbjct: 33  AGNP--QGPSPQGGNKPQGPPPP---PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKS 87

Query: 509 PSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTS 568
            SP S P +P     PP QG   Q  P  GG       +P   P P +  GPP      S
Sbjct: 88  RSPRSPPGKP---QGPPPQGGKPQGPPPQGG------NKPQGPPPPGKPQGPPAQGGSKS 138

Query: 569 VSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPV--PRTGPPTTQQPRPSGP 626
            S  +PP     PP  QQ    PQ PP PAG   Q  QA P   P+  P   Q  RPS P
Sbjct: 139 QSARSPPGKPQGPP--QQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 196



 Score = 84.7 bits (208), Expect = 3e-16
 Identities = 58/169 (34%), Positives = 66/169 (39%), Gaps = 17/169 (10%)

Query: 497 GP-PAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPA----ARPPAS 551
           GP P G   PQ  P P   PQ P     PP  G   Q  P  G P  PP     +R P S
Sbjct: 38  GPSPQGGNKPQGPPPPPGKPQGP-----PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRS 92

Query: 552 PSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVP 611
           P  + Q  PPQ  +        PP   G  P G    G PQ PP   G   Q++++ P  
Sbjct: 93  PPGKPQGPPPQGGKPQG-----PPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGK 147

Query: 612 RTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVP--PPATAAAGGPPHP 658
             GPP  +   P GP P     PQ  Q P    P  PP     G P  P
Sbjct: 148 PQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 196



 Score = 74.7 bits (182), Expect = 3e-13
 Identities = 72/214 (33%), Positives = 87/214 (40%), Gaps = 47/214 (21%)

Query: 405 LIVELVVNKMAQALPRQRQRDASPGR-GSHGQTPSPGALPLGRQTSQQPAGPPAQ-QRPP 462
           L V L+    AQ L     ++ SP     + Q PSP     G    Q P  PP + Q PP
Sbjct: 6   LSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQ----GGNKPQGPPPPPGKPQGPP 61

Query: 463 PQGGPPQPGPGP--QRQGPPLQ--------------QRPPPQGQQHLSGLGPPAGSPLPQ 506
           PQGG    GP P  + QGPP Q              Q PPPQG +      PP G   PQ
Sbjct: 62  PQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGP--PPQGGNKPQ 119

Query: 507 RLPSPTSAPQQPASQA--------APPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQA 558
             P P   PQ P +Q         +PP + QG   +     P  PP   PPA  +PQ+  
Sbjct: 120 G-PPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQE-GNNPQGPP---PPAGGNPQQPQ 174

Query: 559 GPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQ 592
            PP    Q       PP+    PP G +   PPQ
Sbjct: 175 APPAGQPQ------GPPR----PPQGGRPSRPPQ 198



 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 56/144 (38%), Positives = 64/144 (44%), Gaps = 25/144 (17%)

Query: 536 VAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPP-GGQQRQGPPQKP 594
           +AG P  P    P     PQ   GPP          P P K  G PP GG + QGPP  P
Sbjct: 32  IAGNPQGP---SPQGGNKPQ---GPP----------PPPGKPQGPPPQGGNKPQGPP--P 73

Query: 595 PG-PAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAG 653
           PG P GP  Q  ++   PR+ P   Q P P G  P G P PQ   KP Q  PPP      
Sbjct: 74  PGKPQGPPPQGDKSRS-PRSPPGKPQGPPPQGGKPQG-PPPQGGNKP-QGPPPPGKPQ-- 128

Query: 654 GPPHPQLNKSQSLTNAFNLPEPAP 677
           GPP    +KSQS  +    P+  P
Sbjct: 129 GPPAQGGSKSQSARSPPGKPQGPP 152



 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 50/148 (33%), Positives = 60/148 (40%), Gaps = 21/148 (14%)

Query: 549 PASPSPQ---RQAGPPQATRQTSVSGPAPP---KASGAPPGGQQRQGPPQKPPGPAGPTR 602
           P  PSPQ   +  GPP    +    GP P    K  G PP G+  QGPP     P G   
Sbjct: 36  PQGPSPQGGNKPQGPPPPPGKPQ--GPPPQGGNKPQGPPPPGK-PQGPP-----PQGDKS 87

Query: 603 QASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPA------TAAAGGPP 656
           ++ ++ P    GPP  Q  +P GP P G  KPQ    P +   PPA       +A   P 
Sbjct: 88  RSPRSPPGKPQGPP-PQGGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPG 146

Query: 657 HPQLNKSQSLTNAFNLPEPAPPRPSLSQ 684
            PQ    Q   N    P PA   P   Q
Sbjct: 147 KPQGPPQQEGNNPQGPPPPAGGNPQQPQ 174



 Score = 38.5 bits (88), Expect = 0.022
 Identities = 37/127 (29%), Positives = 48/127 (37%), Gaps = 26/127 (20%)

Query: 586 QRQGPPQKPPGPAGPTRQASQA--GPVPRTGPPTTQQP------RPSGPGPAGRP----- 632
           Q + P      P GP+ Q      GP P  G P  Q P      +P GP P G+P     
Sbjct: 25  QEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKP--QGPPPQGGNKPQGPPPPGKPQGPPP 82

Query: 633 ---KPQLAQKP--SQDVPPPATAAAGGPPHPQLNKSQSLTNAFNLPEPAPPRPSLSQDEV 687
              K +  + P      PPP      GPP    NK Q        P P  P+   +Q   
Sbjct: 83  QGDKSRSPRSPPGKPQGPPPQGGKPQGPPPQGGNKPQ------GPPPPGKPQGPPAQGGS 136

Query: 688 KAETIRS 694
           K+++ RS
Sbjct: 137 KSQSARS 143



 Score = 31.6 bits (70), Expect = 2.6
 Identities = 15/42 (35%), Positives = 17/42 (40%), Gaps = 5/42 (11%)

Query: 27 RPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSP 68
          +PQ PPPP     PG   GP      +  G  P   P  P P
Sbjct: 46 KPQGPPPP-----PGKPQGPPPQGGNKPQGPPPPGKPQGPPP 82



 Score = 31.2 bits (69), Expect = 3.4
 Identities = 19/58 (32%), Positives = 22/58 (37%), Gaps = 5/58 (8%)

Query: 16  NLPNGYMTDLQRPQPPPP-----PPGAHSPGATPGPGTATAERSSGVAPAASPAAPSP 68
           N P G      +PQ PPP     P G   PG   GP     +  S  +P   P  P P
Sbjct: 45  NKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPP 102


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 80/287 (27%), Positives = 98/287 (34%), Gaps = 60/287 (20%)

Query: 430  RGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQR----P 485
            +G+ G +  PG    G    Q PAGPP ++  P   GP      P  QG   Q+     P
Sbjct: 929  KGARGDSGPPGRA--GEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLP 986

Query: 486  PPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAP----PTQGQGRQSRPVAGGP- 540
              +G++   GL  P+G P  Q  P  +     P     P    P    GR+  P A GP 
Sbjct: 987  GQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPP 1046

Query: 541  ------------------GAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPP 582
                              GAP A  PP SP P    G      +    GP  P       
Sbjct: 1047 GRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGAR 1106

Query: 583  GGQQRQGPP-----------------------QKPPGPAGPTRQASQAGPVPRTGPPTTQ 619
            G Q  QGP                        Q  PGP GP+     +GP   +GP    
Sbjct: 1107 GIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPP 1166

Query: 620  QP-RPSG-------PGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHP 658
             P  PSG       PGP G P P+     +    PP      GPP P
Sbjct: 1167 GPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGP 1213



 Score = 86.3 bits (212), Expect = 9e-17
 Identities = 79/254 (31%), Positives = 93/254 (36%), Gaps = 38/254 (14%)

Query: 429  GRGSHGQTPSPGALPLGRQTSQQPAGPP-------AQQRPPPQGGPPQPGPGPQRQGPPL 481
            GRG  G    PG  P G    +   GPP       A+  P  +G    PGP      P  
Sbjct: 784  GRGLTGPIGPPG--PAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGA 841

Query: 482  QQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPG 541
              +P  +G+Q  +G    AG+P PQ  PS    PQ P      P   +G Q  P  G  G
Sbjct: 842  DGQPGAKGEQGEAGQKGDAGAPGPQG-PSGAPGPQGPTG-VTGPKGARGAQGPP--GATG 897

Query: 542  APPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPP--QKPPGPAG 599
             P AA     P      GPP     +   GP   +    PPG   R G P  Q P GP G
Sbjct: 898  FPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPG---RAGEPGLQGPAGPPG 954

Query: 600  PTRQASQAGPVPRTGPPTTQ-----------------QPRPSGPGPAGRPKPQLAQKPSQ 642
               +    GP    GPP  Q                 +  P  PGP+G P  Q A   S 
Sbjct: 955  EKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASG 1014

Query: 643  DVPPPATAAAGGPP 656
            D  PP      GPP
Sbjct: 1015 DRGPPGPV---GPP 1025



 Score = 77.4 bits (189), Expect = 4e-14
 Identities = 65/217 (29%), Positives = 81/217 (37%), Gaps = 18/217 (8%)

Query: 419 PRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPP-QPGPGPQRQ 477
           P  +    SPG         P  LP G +    PAG    +    Q GP   PGP     
Sbjct: 305 PGVKGESGSPGENGSPGPMGPRGLP-GERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAG 363

Query: 478 GPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVA 537
           GP     P  +G+   +G   P G+  P+  P    +P    +   P T G         
Sbjct: 364 GPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDG----IPGAK 419

Query: 538 GGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPG--GQQRQGPPQKPP 595
           G  GAP  A  P  P P+   GP  AT      GP  PK     PG  G + +  P+  P
Sbjct: 420 GSAGAPGIAGAPGFPGPRGPPGPQGAT------GPLGPKGQTGEPGIAGFKGEQGPKGEP 473

Query: 596 GPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRP 632
           GPAGP      AG   + G     +  P G GP G P
Sbjct: 474 GPAGPQGAPGPAGEEGKRG----ARGEPGGVGPIGPP 506



 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 92/321 (28%), Positives = 108/321 (33%), Gaps = 69/321 (21%)

Query: 412 NKMAQALPRQRQRDASPGR----GSHGQTPSPGALPLGRQTSQQPAGP----------PA 457
           +K  +  P  R RD  PG     G  G    PG   LG   + Q AG             
Sbjct: 139 DKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGV 198

Query: 458 QQRPP-PQG--GPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSA 514
            Q P  P G  GPP P   P  QG   Q  P   G+  +SG   P G P P   P     
Sbjct: 199 MQGPMGPMGPRGPPGPAGAPGPQG--FQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGE 256

Query: 515 PQQP--ASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSG- 571
             +P  A +  PP     R      G PG       P     + +AG P    ++   G 
Sbjct: 257 AGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGE 316

Query: 572 ---PAPPKASGAPPGGQQRQGP--------------PQKPPGPAGPTR---------QAS 605
              P P    G P G + R GP              P  PPGP GP              
Sbjct: 317 NGSPGPMGPRGLP-GERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKG 375

Query: 606 QAGPVPRTGPPTTQQPR-----PSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQL 660
           +AGP    GP   Q PR     P  PGPAG      +  P  D  P A  +AG P     
Sbjct: 376 EAGPTGARGPEGAQGPRGEPGTPGSPGPAG-----ASGNPGTDGIPGAKGSAGAP----- 425

Query: 661 NKSQSLTNAFNLPEP-APPRP 680
                +  A   P P  PP P
Sbjct: 426 ----GIAGAPGFPGPRGPPGP 442



 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 71/239 (29%), Positives = 86/239 (35%), Gaps = 41/239 (17%)

Query: 428 PGR-GSHGQTPSPG-ALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRP 485
           PG+ G  G    PG A P G +  Q   GP   Q  P   GPP  G  P  QG P +   
Sbjct: 632 PGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGA 691

Query: 486 P----PQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPG 541
           P    P+G++   G     GSP  Q L  P   P  P           G      A GP 
Sbjct: 692 PGLVGPRGERGFPG---ERGSPGAQGLQGPRGLPGTP-----------GTDGPKGASGPA 737

Query: 542 APPAARPP----ASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGP 597
            PP A+ P      P  +  AG           G   P+ +    GG+   G P  PPGP
Sbjct: 738 GPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTG-PIGPPGP 796

Query: 598 AGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPP 656
           AG   +  + GP                PGPAG    + A     +  PP  A   GPP
Sbjct: 797 AGANGEKGEVGP----------------PGPAGSAGARGAPGERGETGPPGPAGFAGPP 839



 Score = 74.7 bits (182), Expect = 3e-13
 Identities = 75/246 (30%), Positives = 85/246 (34%), Gaps = 27/246 (10%)

Query: 430 RGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQG 489
           RG  G+  SPGA   G Q  +   G P    P    GP  P   P  QGPP  Q  P  G
Sbjct: 701 RGFPGERGSPGAQ--GLQGPRGLPGTPGTDGPKGASGPAGP---PGAQGPPGLQGMP--G 753

Query: 490 QQHLSGLGPPAGSPLPQRLPSPTSAPQQ------------PASQAAPPTQGQGRQSRPV- 536
           ++  +G+  P G         P  AP +            P    A   +G+     P  
Sbjct: 754 ERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAG 813

Query: 537 -AGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPP 595
            AG  GAP        P P   AGPP A  Q    G           G    QG P   P
Sbjct: 814 SAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQG-PSGAP 872

Query: 596 GPAGPTRQASQAGPVPRTGPP-TTQQPRPSG----PGPAGRPKPQLAQKPSQDVPPPATA 650
           GP GPT      G     GPP  T  P  +G    PG  G P P     PS    P    
Sbjct: 873 GPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGAR 932

Query: 651 AAGGPP 656
              GPP
Sbjct: 933 GDSGPP 938



 Score = 69.7 bits (169), Expect = 9e-12
 Identities = 84/270 (31%), Positives = 99/270 (36%), Gaps = 33/270 (12%)

Query: 430 RGSHGQTPSPGALPLGRQTSQQPAGPPAQQ----RPPPQGGPPQPGP----GPQRQGPPL 481
           RG  G   SPG  P G   +    G P  +     P   G P  PGP    GPQ    PL
Sbjct: 392 RGEPGTPGSPG--PAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPL 449

Query: 482 QQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPG 541
                P+GQ    G+    G   P+  P P  A  Q A   A     +G +  P   GP 
Sbjct: 450 G----PKGQTGEPGIAGFKGEQGPKGEPGP--AGPQGAPGPAGEEGKRGARGEPGGVGPI 503

Query: 542 APPAARPPAS----PSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGP 597
            PP  R        P     AGP  A  +   SG A PK +   PG   R G P   PG 
Sbjct: 504 GPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPG---RPGEPGL-PGA 559

Query: 598 AGPTRQASQAGPVPRTGPPTT--QQPRPSGPGPAG-RPKPQLAQKP---SQDVPPPATAA 651
            G T +   AGP  + GP     +  RP  PGP G R +P +   P     +  P     
Sbjct: 560 RGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGE 619

Query: 652 AGGPPHPQLN---KSQSLTNAFNLPEPAPP 678
            G P  P L         T A   P PA P
Sbjct: 620 KGLPGAPGLRGLPGKDGETGAAGPPGPAGP 649



 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 71/248 (28%), Positives = 86/248 (34%), Gaps = 40/248 (16%)

Query: 416  QALPRQRQRDASPG-RGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQ---PG 471
            Q L  QR     PG RG  G    PG  P G    Q   G    + PP   GPP    P 
Sbjct: 974  QGLAGQRGIVGLPGQRGERGFPGLPG--PSGEPGKQGAPGASGDRGPPGPVGPPGLTGPA 1031

Query: 472  PGPQRQGPPLQQRPPPQ-------GQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAP 524
              P R+G P    PP +       G +  +G     G+P P   P P     +   +   
Sbjct: 1032 GEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEA 1091

Query: 525  PTQGQGRQSRPVAG----GPGAPPAARPPASPSPQRQA-------------GPPQATRQT 567
              QG    S P       GP  P   +  A    +R               GPP  +   
Sbjct: 1092 GAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQ 1151

Query: 568  SVSGPAPP---KASGAPPGGQQRQGP-----PQKPPGPAGPTRQASQAGPVPRTGPPTTQ 619
              SGPA P   +    P G   + G      P  PPGP G + +   AGP    GPP   
Sbjct: 1152 GASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPP--G 1209

Query: 620  QPRPSGPG 627
             P P GPG
Sbjct: 1210 PPGPPGPG 1217



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 71/243 (29%), Positives = 87/243 (35%), Gaps = 37/243 (15%)

Query: 426 ASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRP 485
           AS   G  GQ   PG +    +    P GPP      PQG   + GP   R     +  P
Sbjct: 96  ASGQPGPKGQKGEPGDI----KDIVGPKGPPG-----PQGPAGEQGPRGDRGDKGEKGAP 146

Query: 486 PPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAP--PTQGQGRQSRPVAG----- 538
            P+G+    G     G P P   P P       A+Q A     +  G Q   + G     
Sbjct: 147 GPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPM 206

Query: 539 GPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPA 598
           GP  PP   P  +P PQ   G P    +  VSGP  P+    PPG          PPG  
Sbjct: 207 GPRGPPG--PAGAPGPQGFQGNPGEPGEPGVSGPMGPR---GPPG----------PPGKP 251

Query: 599 GPTRQASQAGPVPRTGPPTTQQPR--PSGPGPAG----RPKPQLAQKPSQDVPPPATAAA 652
           G   +A + G     GPP  Q  R  P  PG  G    R  P L     +   P     +
Sbjct: 252 GDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGES 311

Query: 653 GGP 655
           G P
Sbjct: 312 GSP 314



 Score = 63.5 bits (153), Expect = 6e-10
 Identities = 74/250 (29%), Positives = 88/250 (35%), Gaps = 38/250 (15%)

Query: 431 GSHGQTPSPGALPL-GRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPP-------LQ 482
           G  G+  +PG     G+     P G P ++ P    GP      P R G P       L 
Sbjct: 504 GPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLT 563

Query: 483 QRPP---PQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGG 539
            RP    PQG+   SG     G P P   P P  A  QP     P  +G         G 
Sbjct: 564 GRPGDAGPQGKVGPSGAPGEDGRPGP---PGPQGARGQPGVMGFPGPKGAN-------GE 613

Query: 540 PGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPP--QKPPGP 597
           PG       P +P  +   G P    +T  +GP  P       G Q   GP   Q  PGP
Sbjct: 614 PGKAGEKGLPGAPGLR---GLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGP 670

Query: 598 AGPTRQASQAGP--VP-RTGPPTTQQPRPSG--PGPAGRPKPQ-------LAQKPSQDVP 645
            GP  +  + G   VP   G P    PR     PG  G P  Q       L   P  D P
Sbjct: 671 PGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGP 730

Query: 646 PPATAAAGGP 655
             A+  AG P
Sbjct: 731 KGASGPAGPP 740



 Score = 60.1 bits (144), Expect = 7e-09
 Identities = 73/255 (28%), Positives = 83/255 (32%), Gaps = 48/255 (18%)

Query: 418  LPRQRQRDASPG----RGSHGQTPSPGAL-------PLGRQTSQQPAGPPAQQRPPPQGG 466
            LP QR     PG     G  G+  +PGA        P+G      PAG P ++  P   G
Sbjct: 985  LPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADG 1044

Query: 467  PP-------------QPGP--GPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSP 511
            PP             + G    P   GPP    P P G     G    AG+  P     P
Sbjct: 1045 PPGRDGAAGVKGDRGETGAVGAPGAPGPP--GSPGPAGPTGKQGDRGEAGAQGPMGPSGP 1102

Query: 512  TSA-----PQQPASQAA----PPTQG-------QGRQSRPVAGGPGAPPAARPPASPSPQ 555
              A     PQ P         P  +G        G Q  P   GP     A  PA PS  
Sbjct: 1103 AGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGP 1162

Query: 556  RQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGP--PQKPPGPAGPTRQASQAGPVPRT 613
            R  GPP     +   G         PPG + R G   P  PPG  GP       GP    
Sbjct: 1163 R--GPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDM 1220

Query: 614  GPPTTQQPRPSGPGP 628
                   PR  GP P
Sbjct: 1221 SAFAGLGPREKGPDP 1235



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 26/65 (40%), Positives = 29/65 (44%), Gaps = 13/65 (20%)

Query: 431  GSHGQTPSPGAL----PLGRQTSQQPAGPPAQQRPPPQGGPPQP--------GPGPQRQG 478
            G  G    PG +    P GR     PAGPP    PP   GPP P        G GP+ +G
Sbjct: 1173 GKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKG 1232

Query: 479  P-PLQ 482
            P PLQ
Sbjct: 1233 PDPLQ 1237



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 29/93 (31%), Positives = 34/93 (36%), Gaps = 16/93 (17%)

Query: 554 PQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPT------------ 601
           P  +  P   T   + SG   PK     PG  +    P+ PPGP GP             
Sbjct: 81  PFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDK 140

Query: 602 RQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKP 634
            +    GP  R G P T    P  PGP G P P
Sbjct: 141 GEKGAPGPRGRDGEPGT----PGNPGPPGPPGP 169



 Score = 33.1 bits (74), Expect = 0.91
 Identities = 27/94 (28%), Positives = 34/94 (36%), Gaps = 18/94 (19%)

Query: 572 PAPPKASGAPPGGQQRQGPPQK------PPGPAGPTRQASQAGPVPRTGPPTTQQPRPSG 625
           P     +   PG + ++G P        P GP GP   A + GP    G     +     
Sbjct: 90  PTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRG----DKGEKGA 145

Query: 626 PGPAGRP-KPQLAQKPSQDVPPPATAAAGGPPHP 658
           PGP GR  +P     P    PP       GPP P
Sbjct: 146 PGPRGRDGEPGTPGNPGPPGPP-------GPPGP 172



 Score = 31.2 bits (69), Expect = 3.4
 Identities = 16/54 (29%), Positives = 24/54 (44%)

Query: 23  TDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGGGF 76
           T  + P+    P G      +PGP  A+    +   P A  +A +PG +G  GF
Sbjct: 380 TGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGF 433


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 80/287 (27%), Positives = 98/287 (34%), Gaps = 60/287 (20%)

Query: 430  RGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQR----P 485
            +G+ G +  PG    G    Q PAGPP ++  P   GP      P  QG   Q+     P
Sbjct: 860  KGARGDSGPPGRA--GEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLP 917

Query: 486  PPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAP----PTQGQGRQSRPVAGGP- 540
              +G++   GL  P+G P  Q  P  +     P     P    P    GR+  P A GP 
Sbjct: 918  GQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPP 977

Query: 541  ------------------GAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPP 582
                              GAP A  PP SP P    G      +    GP  P       
Sbjct: 978  GRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGAR 1037

Query: 583  GGQQRQGPP-----------------------QKPPGPAGPTRQASQAGPVPRTGPPTTQ 619
            G Q  QGP                        Q  PGP GP+     +GP   +GP    
Sbjct: 1038 GIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPP 1097

Query: 620  QP-RPSG-------PGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHP 658
             P  PSG       PGP G P P+     +    PP      GPP P
Sbjct: 1098 GPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGP 1144



 Score = 86.3 bits (212), Expect = 9e-17
 Identities = 79/254 (31%), Positives = 93/254 (36%), Gaps = 38/254 (14%)

Query: 429 GRGSHGQTPSPGALPLGRQTSQQPAGPP-------AQQRPPPQGGPPQPGPGPQRQGPPL 481
           GRG  G    PG  P G    +   GPP       A+  P  +G    PGP      P  
Sbjct: 715 GRGLTGPIGPPG--PAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGA 772

Query: 482 QQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPG 541
             +P  +G+Q  +G    AG+P PQ  PS    PQ P      P   +G Q  P  G  G
Sbjct: 773 DGQPGAKGEQGEAGQKGDAGAPGPQG-PSGAPGPQGPTG-VTGPKGARGAQGPP--GATG 828

Query: 542 APPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPP--QKPPGPAG 599
            P AA     P      GPP     +   GP   +    PPG   R G P  Q P GP G
Sbjct: 829 FPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPG---RAGEPGLQGPAGPPG 885

Query: 600 PTRQASQAGPVPRTGPPTTQ-----------------QPRPSGPGPAGRPKPQLAQKPSQ 642
              +    GP    GPP  Q                 +  P  PGP+G P  Q A   S 
Sbjct: 886 EKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASG 945

Query: 643 DVPPPATAAAGGPP 656
           D  PP      GPP
Sbjct: 946 DRGPPGPV---GPP 956



 Score = 77.4 bits (189), Expect = 4e-14
 Identities = 65/217 (29%), Positives = 81/217 (37%), Gaps = 18/217 (8%)

Query: 419 PRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPP-QPGPGPQRQ 477
           P  +    SPG         P  LP G +    PAG    +    Q GP   PGP     
Sbjct: 236 PGVKGESGSPGENGSPGPMGPRGLP-GERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAG 294

Query: 478 GPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVA 537
           GP     P  +G+   +G   P G+  P+  P    +P    +   P T G         
Sbjct: 295 GPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDG----IPGAK 350

Query: 538 GGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPG--GQQRQGPPQKPP 595
           G  GAP  A  P  P P+   GP  AT      GP  PK     PG  G + +  P+  P
Sbjct: 351 GSAGAPGIAGAPGFPGPRGPPGPQGAT------GPLGPKGQTGEPGIAGFKGEQGPKGEP 404

Query: 596 GPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRP 632
           GPAGP      AG   + G     +  P G GP G P
Sbjct: 405 GPAGPQGAPGPAGEEGKRG----ARGEPGGVGPIGPP 437



 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 92/321 (28%), Positives = 108/321 (33%), Gaps = 69/321 (21%)

Query: 412 NKMAQALPRQRQRDASPGR----GSHGQTPSPGALPLGRQTSQQPAGP----------PA 457
           +K  +  P  R RD  PG     G  G    PG   LG   + Q AG             
Sbjct: 70  DKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGV 129

Query: 458 QQRPP-PQG--GPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSA 514
            Q P  P G  GPP P   P  QG   Q  P   G+  +SG   P G P P   P     
Sbjct: 130 MQGPMGPMGPRGPPGPAGAPGPQG--FQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGE 187

Query: 515 PQQP--ASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSG- 571
             +P  A +  PP     R      G PG       P     + +AG P    ++   G 
Sbjct: 188 AGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGE 247

Query: 572 ---PAPPKASGAPPGGQQRQGP--------------PQKPPGPAGPTR---------QAS 605
              P P    G P G + R GP              P  PPGP GP              
Sbjct: 248 NGSPGPMGPRGLP-GERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKG 306

Query: 606 QAGPVPRTGPPTTQQPR-----PSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQL 660
           +AGP    GP   Q PR     P  PGPAG      +  P  D  P A  +AG P     
Sbjct: 307 EAGPTGARGPEGAQGPRGEPGTPGSPGPAG-----ASGNPGTDGIPGAKGSAGAP----- 356

Query: 661 NKSQSLTNAFNLPEP-APPRP 680
                +  A   P P  PP P
Sbjct: 357 ----GIAGAPGFPGPRGPPGP 373



 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 71/239 (29%), Positives = 86/239 (35%), Gaps = 41/239 (17%)

Query: 428 PGR-GSHGQTPSPG-ALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRP 485
           PG+ G  G    PG A P G +  Q   GP   Q  P   GPP  G  P  QG P +   
Sbjct: 563 PGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGA 622

Query: 486 P----PQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPG 541
           P    P+G++   G     GSP  Q L  P   P  P           G      A GP 
Sbjct: 623 PGLVGPRGERGFPG---ERGSPGAQGLQGPRGLPGTP-----------GTDGPKGASGPA 668

Query: 542 APPAARPP----ASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGP 597
            PP A+ P      P  +  AG           G   P+ +    GG+   G P  PPGP
Sbjct: 669 GPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTG-PIGPPGP 727

Query: 598 AGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPP 656
           AG   +  + GP                PGPAG    + A     +  PP  A   GPP
Sbjct: 728 AGANGEKGEVGP----------------PGPAGSAGARGAPGERGETGPPGPAGFAGPP 770



 Score = 74.7 bits (182), Expect = 3e-13
 Identities = 75/246 (30%), Positives = 85/246 (34%), Gaps = 27/246 (10%)

Query: 430 RGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQG 489
           RG  G+  SPGA   G Q  +   G P    P    GP  P   P  QGPP  Q  P  G
Sbjct: 632 RGFPGERGSPGAQ--GLQGPRGLPGTPGTDGPKGASGPAGP---PGAQGPPGLQGMP--G 684

Query: 490 QQHLSGLGPPAGSPLPQRLPSPTSAPQQ------------PASQAAPPTQGQGRQSRPV- 536
           ++  +G+  P G         P  AP +            P    A   +G+     P  
Sbjct: 685 ERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAG 744

Query: 537 -AGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPP 595
            AG  GAP        P P   AGPP A  Q    G           G    QG P   P
Sbjct: 745 SAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQG-PSGAP 803

Query: 596 GPAGPTRQASQAGPVPRTGPP-TTQQPRPSG----PGPAGRPKPQLAQKPSQDVPPPATA 650
           GP GPT      G     GPP  T  P  +G    PG  G P P     PS    P    
Sbjct: 804 GPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGAR 863

Query: 651 AAGGPP 656
              GPP
Sbjct: 864 GDSGPP 869



 Score = 69.7 bits (169), Expect = 9e-12
 Identities = 84/270 (31%), Positives = 99/270 (36%), Gaps = 33/270 (12%)

Query: 430 RGSHGQTPSPGALPLGRQTSQQPAGPPAQQ----RPPPQGGPPQPGP----GPQRQGPPL 481
           RG  G   SPG  P G   +    G P  +     P   G P  PGP    GPQ    PL
Sbjct: 323 RGEPGTPGSPG--PAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPL 380

Query: 482 QQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPG 541
                P+GQ    G+    G   P+  P P  A  Q A   A     +G +  P   GP 
Sbjct: 381 G----PKGQTGEPGIAGFKGEQGPKGEPGP--AGPQGAPGPAGEEGKRGARGEPGGVGPI 434

Query: 542 APPAARPPAS----PSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGP 597
            PP  R        P     AGP  A  +   SG A PK +   PG   R G P   PG 
Sbjct: 435 GPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPG---RPGEPGL-PGA 490

Query: 598 AGPTRQASQAGPVPRTGPPTT--QQPRPSGPGPAG-RPKPQLAQKP---SQDVPPPATAA 651
            G T +   AGP  + GP     +  RP  PGP G R +P +   P     +  P     
Sbjct: 491 RGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGE 550

Query: 652 AGGPPHPQLN---KSQSLTNAFNLPEPAPP 678
            G P  P L         T A   P PA P
Sbjct: 551 KGLPGAPGLRGLPGKDGETGAAGPPGPAGP 580



 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 71/248 (28%), Positives = 86/248 (34%), Gaps = 40/248 (16%)

Query: 416  QALPRQRQRDASPG-RGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQ---PG 471
            Q L  QR     PG RG  G    PG  P G    Q   G    + PP   GPP    P 
Sbjct: 905  QGLAGQRGIVGLPGQRGERGFPGLPG--PSGEPGKQGAPGASGDRGPPGPVGPPGLTGPA 962

Query: 472  PGPQRQGPPLQQRPPPQ-------GQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAP 524
              P R+G P    PP +       G +  +G     G+P P   P P     +   +   
Sbjct: 963  GEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEA 1022

Query: 525  PTQGQGRQSRPVAG----GPGAPPAARPPASPSPQRQA-------------GPPQATRQT 567
              QG    S P       GP  P   +  A    +R               GPP  +   
Sbjct: 1023 GAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQ 1082

Query: 568  SVSGPAPP---KASGAPPGGQQRQGP-----PQKPPGPAGPTRQASQAGPVPRTGPPTTQ 619
              SGPA P   +    P G   + G      P  PPGP G + +   AGP    GPP   
Sbjct: 1083 GASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPP--G 1140

Query: 620  QPRPSGPG 627
             P P GPG
Sbjct: 1141 PPGPPGPG 1148



 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 69/238 (28%), Positives = 85/238 (35%), Gaps = 37/238 (15%)

Query: 431 GSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQ 490
           G  GQ   PG +    +    P GPP      PQG   + GP   R     +  P P+G+
Sbjct: 32  GPKGQKGEPGDI----KDIVGPKGPPG-----PQGPAGEQGPRGDRGDKGEKGAPGPRGR 82

Query: 491 QHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAP--PTQGQGRQSRPVAG-----GPGAP 543
               G     G P P   P P       A+Q A     +  G Q   + G     GP  P
Sbjct: 83  DGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGP 142

Query: 544 PAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQ 603
           P   P  +P PQ   G P    +  VSGP  P+    PPG          PPG  G   +
Sbjct: 143 PG--PAGAPGPQGFQGNPGEPGEPGVSGPMGPR---GPPG----------PPGKPGDDGE 187

Query: 604 ASQAGPVPRTGPPTTQQPR--PSGPGPAG----RPKPQLAQKPSQDVPPPATAAAGGP 655
           A + G     GPP  Q  R  P  PG  G    R  P L     +   P     +G P
Sbjct: 188 AGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSP 245



 Score = 63.5 bits (153), Expect = 6e-10
 Identities = 74/250 (29%), Positives = 88/250 (35%), Gaps = 38/250 (15%)

Query: 431 GSHGQTPSPGALPL-GRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPP-------LQ 482
           G  G+  +PG     G+     P G P ++ P    GP      P R G P       L 
Sbjct: 435 GPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLT 494

Query: 483 QRPP---PQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGG 539
            RP    PQG+   SG     G P P   P P  A  QP     P  +G         G 
Sbjct: 495 GRPGDAGPQGKVGPSGAPGEDGRPGP---PGPQGARGQPGVMGFPGPKGAN-------GE 544

Query: 540 PGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPP--QKPPGP 597
           PG       P +P  +   G P    +T  +GP  P       G Q   GP   Q  PGP
Sbjct: 545 PGKAGEKGLPGAPGLR---GLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGP 601

Query: 598 AGPTRQASQAGP--VP-RTGPPTTQQPRPSG--PGPAGRPKPQ-------LAQKPSQDVP 645
            GP  +  + G   VP   G P    PR     PG  G P  Q       L   P  D P
Sbjct: 602 PGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGP 661

Query: 646 PPATAAAGGP 655
             A+  AG P
Sbjct: 662 KGASGPAGPP 671



 Score = 60.1 bits (144), Expect = 7e-09
 Identities = 73/255 (28%), Positives = 83/255 (32%), Gaps = 48/255 (18%)

Query: 418  LPRQRQRDASPG----RGSHGQTPSPGAL-------PLGRQTSQQPAGPPAQQRPPPQGG 466
            LP QR     PG     G  G+  +PGA        P+G      PAG P ++  P   G
Sbjct: 916  LPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADG 975

Query: 467  PP-------------QPGP--GPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSP 511
            PP             + G    P   GPP    P P G     G    AG+  P     P
Sbjct: 976  PPGRDGAAGVKGDRGETGAVGAPGAPGPP--GSPGPAGPTGKQGDRGEAGAQGPMGPSGP 1033

Query: 512  TSA-----PQQPASQAA----PPTQG-------QGRQSRPVAGGPGAPPAARPPASPSPQ 555
              A     PQ P         P  +G        G Q  P   GP     A  PA PS  
Sbjct: 1034 AGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGP 1093

Query: 556  RQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGP--PQKPPGPAGPTRQASQAGPVPRT 613
            R  GPP     +   G         PPG + R G   P  PPG  GP       GP    
Sbjct: 1094 R--GPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDM 1151

Query: 614  GPPTTQQPRPSGPGP 628
                   PR  GP P
Sbjct: 1152 SAFAGLGPREKGPDP 1166



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 26/65 (40%), Positives = 29/65 (44%), Gaps = 13/65 (20%)

Query: 431  GSHGQTPSPGAL----PLGRQTSQQPAGPPAQQRPPPQGGPPQP--------GPGPQRQG 478
            G  G    PG +    P GR     PAGPP    PP   GPP P        G GP+ +G
Sbjct: 1104 GKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKG 1163

Query: 479  P-PLQ 482
            P PLQ
Sbjct: 1164 PDPLQ 1168



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 26/84 (30%), Positives = 32/84 (38%), Gaps = 18/84 (21%)

Query: 582 PGGQQRQGPPQK------PPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRP-KP 634
           PG + ++G P        P GP GP   A + GP    G     +     PGP GR  +P
Sbjct: 31  PGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRG----DKGEKGAPGPRGRDGEP 86

Query: 635 QLAQKPSQDVPPPATAAAGGPPHP 658
                P    PP       GPP P
Sbjct: 87  GTPGNPGPPGPP-------GPPGP 103



 Score = 31.2 bits (69), Expect = 3.4
 Identities = 16/54 (29%), Positives = 24/54 (44%)

Query: 23  TDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGGGF 76
           T  + P+    P G      +PGP  A+    +   P A  +A +PG +G  GF
Sbjct: 311 TGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGF 364


>gi|192807323 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform A [Homo sapiens]
          Length = 1679

 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 87/292 (29%), Positives = 105/292 (35%), Gaps = 36/292 (12%)

Query: 429 GRGSHGQTPSPGALPL-GRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPP 487
           G   H  +P P + P  G Q S  P G P     P   G    GP P  Q    Q R   
Sbjct: 125 GGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQI 184

Query: 488 QGQQHLSGLGPPAGSPLPQRLPSPTSAPQ-QPASQAAPPTQGQGRQSRPVAGGPGAPPAA 546
              + L+      G PLP  L       +  P  Q   PT      S   A GPG  P  
Sbjct: 185 MAYKMLA-----RGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVS---ATGPGPGPGP 236

Query: 547 RPPASPSPQRQAGPPQATRQTSVSGP--APPKASGAPPGGQQRQGPPQKPPGPAGPTRQA 604
            P   P P     PP  +R   + GP   PP  SG PPG      P Q P GP  P  + 
Sbjct: 237 GPGPGPGP----APPNYSRPHGMGGPNMPPPGPSGVPPG-----MPGQPPGGPPKPWPE- 286

Query: 605 SQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKP--SQDVPPPATAAAGGPPHP---- 658
              GP+     PT+   +   P P GRP P     P  +  V PP T + G P  P    
Sbjct: 287 ---GPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMV 343

Query: 659 QLNKSQSLTNAFNLPEPAPPRPSLSQDEVK-----AETIRSLRKSFASLFSD 705
            L++ QS       P    P   L + E +     A  I+ L     SL  D
Sbjct: 344 PLHQKQSRITPIQKPRGLDPVEILQEREYRLQARIAHRIQELENLPGSLAGD 395



 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 73/257 (28%), Positives = 87/257 (33%), Gaps = 49/257 (19%)

Query: 462 PPQGGPPQPGPGP---QRQGPPLQQRPPPQGQQHLSGLG-----PPAGSPLPQRLPSPTS 513
           PP GG P+PGP P      G  L   P P      S +G     P AG P+P +   P  
Sbjct: 6   PPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQ--GPGG 63

Query: 514 APQQPASQAAPPTQG----------QGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQA 563
            PQ    Q   P +           +  Q + +    G      PP SP  Q   G P  
Sbjct: 64  YPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSP 123

Query: 564 TRQTS-VSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQ-AGPVPRTGPPTTQ-- 619
              +   S P P  ASG   G Q   GP   P   A P     Q  GP P       Q  
Sbjct: 124 LGGSEHASSPVP--ASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLR 181

Query: 620 ------------QPRPSGPGPA---GRPKPQLAQKPSQDVPPPATAAAGGPPHPQLNKSQ 664
                       QP P     A    RP P + Q+    +PPP+ +A G  P P      
Sbjct: 182 AQIMAYKMLARGQPLPDHLQMAVQGKRPMPGM-QQQMPTLPPPSVSATGPGPGPGPGPGP 240

Query: 665 SLTNAFNLPEPAPPRPS 681
                   P PAPP  S
Sbjct: 241 G-------PGPAPPNYS 250



 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 68/211 (32%), Positives = 83/211 (39%), Gaps = 35/211 (16%)

Query: 398 HQDEDKQLIVELVVNKM---AQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAG 454
           +Q++  QL  +++  KM    Q LP   Q          G+ P PG         Q P  
Sbjct: 173 NQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQ------GKRPMPG------MQQQMPTL 220

Query: 455 PP---AQQRPPPQGGP-PQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSP-LPQRLP 509
           PP   +   P P  GP P PGPGP    PP   RP   G  ++   GP    P +P + P
Sbjct: 221 PPPSVSATGPGPGPGPGPGPGPGP---APPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPP 277

Query: 510 S--PTSAPQQPASQAAPPTQGQGRQSRPVAGG--PGAPPAARPPASPSPQRQAGPPQATR 565
              P   P+ P + AA PT    +   P   G    APPA  P ASP       PPQ   
Sbjct: 278 GGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASP-----VMPPQT-- 330

Query: 566 QTSVSGPAPPKASGAPPGGQQRQGPPQKPPG 596
             S   PA P         Q R  P QKP G
Sbjct: 331 -QSPGQPAQPAPMVPLHQKQSRITPIQKPRG 360



 Score = 33.1 bits (74), Expect = 0.91
 Identities = 19/51 (37%), Positives = 23/51 (45%), Gaps = 7/51 (13%)

Query: 30 PPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAA------PSPGSSGGG 74
          P PP  G   PG +PGPG +      G +P  SP +      PSPG    G
Sbjct: 4  PDPPLGGTPRPGPSPGPGPSPG-AMLGPSPGPSPGSAHSMMGPSPGPPSAG 53



 Score = 33.1 bits (74), Expect = 0.91
 Identities = 19/53 (35%), Positives = 24/53 (45%), Gaps = 4/53 (7%)

Query: 28 PQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPG----SSGGGGF 76
          P+P P P    SPGA  GP    +  S+      SP  PS G    + G GG+
Sbjct: 12 PRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQGPGGY 64



 Score = 33.1 bits (74), Expect = 0.91
 Identities = 19/58 (32%), Positives = 22/58 (37%), Gaps = 7/58 (12%)

Query: 22  MTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAAS-------PAAPSPGSSG 72
           M  +Q+  P  PPP   + G  PGPG           P  S       P  P PG SG
Sbjct: 210 MPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSG 267



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 19/46 (41%), Positives = 24/46 (52%), Gaps = 2/46 (4%)

Query: 30  PPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGGG 75
           PPP P   HS G  P P    +E +S   PA+ P++    SSG GG
Sbjct: 108 PPPSPMDQHSQGY-PSP-LGGSEHASSPVPASGPSSGPQMSSGPGG 151


>gi|192807320 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform F [Homo sapiens]
          Length = 1613

 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 87/292 (29%), Positives = 105/292 (35%), Gaps = 36/292 (12%)

Query: 429 GRGSHGQTPSPGALPL-GRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPP 487
           G   H  +P P + P  G Q S  P G P     P   G    GP P  Q    Q R   
Sbjct: 125 GGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQI 184

Query: 488 QGQQHLSGLGPPAGSPLPQRLPSPTSAPQ-QPASQAAPPTQGQGRQSRPVAGGPGAPPAA 546
              + L+      G PLP  L       +  P  Q   PT      S   A GPG  P  
Sbjct: 185 MAYKMLA-----RGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVS---ATGPGPGPGP 236

Query: 547 RPPASPSPQRQAGPPQATRQTSVSGP--APPKASGAPPGGQQRQGPPQKPPGPAGPTRQA 604
            P   P P     PP  +R   + GP   PP  SG PPG      P Q P GP  P  + 
Sbjct: 237 GPGPGPGP----APPNYSRPHGMGGPNMPPPGPSGVPPG-----MPGQPPGGPPKPWPE- 286

Query: 605 SQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKP--SQDVPPPATAAAGGPPHP---- 658
              GP+     PT+   +   P P GRP P     P  +  V PP T + G P  P    
Sbjct: 287 ---GPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMV 343

Query: 659 QLNKSQSLTNAFNLPEPAPPRPSLSQDEVK-----AETIRSLRKSFASLFSD 705
            L++ QS       P    P   L + E +     A  I+ L     SL  D
Sbjct: 344 PLHQKQSRITPIQKPRGLDPVEILQEREYRLQARIAHRIQELENLPGSLAGD 395



 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 73/257 (28%), Positives = 87/257 (33%), Gaps = 49/257 (19%)

Query: 462 PPQGGPPQPGPGP---QRQGPPLQQRPPPQGQQHLSGLG-----PPAGSPLPQRLPSPTS 513
           PP GG P+PGP P      G  L   P P      S +G     P AG P+P +   P  
Sbjct: 6   PPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQ--GPGG 63

Query: 514 APQQPASQAAPPTQG----------QGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQA 563
            PQ    Q   P +           +  Q + +    G      PP SP  Q   G P  
Sbjct: 64  YPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSP 123

Query: 564 TRQTS-VSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQ-AGPVPRTGPPTTQ-- 619
              +   S P P  ASG   G Q   GP   P   A P     Q  GP P       Q  
Sbjct: 124 LGGSEHASSPVP--ASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLR 181

Query: 620 ------------QPRPSGPGPA---GRPKPQLAQKPSQDVPPPATAAAGGPPHPQLNKSQ 664
                       QP P     A    RP P + Q+    +PPP+ +A G  P P      
Sbjct: 182 AQIMAYKMLARGQPLPDHLQMAVQGKRPMPGM-QQQMPTLPPPSVSATGPGPGPGPGPGP 240

Query: 665 SLTNAFNLPEPAPPRPS 681
                   P PAPP  S
Sbjct: 241 G-------PGPAPPNYS 250



 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 68/211 (32%), Positives = 83/211 (39%), Gaps = 35/211 (16%)

Query: 398 HQDEDKQLIVELVVNKM---AQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAG 454
           +Q++  QL  +++  KM    Q LP   Q          G+ P PG         Q P  
Sbjct: 173 NQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQ------GKRPMPG------MQQQMPTL 220

Query: 455 PP---AQQRPPPQGGP-PQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSP-LPQRLP 509
           PP   +   P P  GP P PGPGP    PP   RP   G  ++   GP    P +P + P
Sbjct: 221 PPPSVSATGPGPGPGPGPGPGPGP---APPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPP 277

Query: 510 S--PTSAPQQPASQAAPPTQGQGRQSRPVAGG--PGAPPAARPPASPSPQRQAGPPQATR 565
              P   P+ P + AA PT    +   P   G    APPA  P ASP       PPQ   
Sbjct: 278 GGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASP-----VMPPQT-- 330

Query: 566 QTSVSGPAPPKASGAPPGGQQRQGPPQKPPG 596
             S   PA P         Q R  P QKP G
Sbjct: 331 -QSPGQPAQPAPMVPLHQKQSRITPIQKPRG 360



 Score = 33.1 bits (74), Expect = 0.91
 Identities = 19/51 (37%), Positives = 23/51 (45%), Gaps = 7/51 (13%)

Query: 30 PPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAA------PSPGSSGGG 74
          P PP  G   PG +PGPG +      G +P  SP +      PSPG    G
Sbjct: 4  PDPPLGGTPRPGPSPGPGPSPG-AMLGPSPGPSPGSAHSMMGPSPGPPSAG 53



 Score = 33.1 bits (74), Expect = 0.91
 Identities = 19/53 (35%), Positives = 24/53 (45%), Gaps = 4/53 (7%)

Query: 28 PQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPG----SSGGGGF 76
          P+P P P    SPGA  GP    +  S+      SP  PS G    + G GG+
Sbjct: 12 PRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQGPGGY 64



 Score = 33.1 bits (74), Expect = 0.91
 Identities = 19/58 (32%), Positives = 22/58 (37%), Gaps = 7/58 (12%)

Query: 22  MTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAAS-------PAAPSPGSSG 72
           M  +Q+  P  PPP   + G  PGPG           P  S       P  P PG SG
Sbjct: 210 MPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSG 267



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 19/46 (41%), Positives = 24/46 (52%), Gaps = 2/46 (4%)

Query: 30  PPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGGG 75
           PPP P   HS G  P P    +E +S   PA+ P++    SSG GG
Sbjct: 108 PPPSPMDQHSQGY-PSP-LGGSEHASSPVPASGPSSGPQMSSGPGG 151


>gi|192807318 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform E [Homo sapiens]
          Length = 1614

 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 87/292 (29%), Positives = 105/292 (35%), Gaps = 36/292 (12%)

Query: 429 GRGSHGQTPSPGALPL-GRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPP 487
           G   H  +P P + P  G Q S  P G P     P   G    GP P  Q    Q R   
Sbjct: 125 GGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQI 184

Query: 488 QGQQHLSGLGPPAGSPLPQRLPSPTSAPQ-QPASQAAPPTQGQGRQSRPVAGGPGAPPAA 546
              + L+      G PLP  L       +  P  Q   PT      S   A GPG  P  
Sbjct: 185 MAYKMLA-----RGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVS---ATGPGPGPGP 236

Query: 547 RPPASPSPQRQAGPPQATRQTSVSGP--APPKASGAPPGGQQRQGPPQKPPGPAGPTRQA 604
            P   P P     PP  +R   + GP   PP  SG PPG      P Q P GP  P  + 
Sbjct: 237 GPGPGPGP----APPNYSRPHGMGGPNMPPPGPSGVPPG-----MPGQPPGGPPKPWPE- 286

Query: 605 SQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKP--SQDVPPPATAAAGGPPHP---- 658
              GP+     PT+   +   P P GRP P     P  +  V PP T + G P  P    
Sbjct: 287 ---GPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMV 343

Query: 659 QLNKSQSLTNAFNLPEPAPPRPSLSQDEVK-----AETIRSLRKSFASLFSD 705
            L++ QS       P    P   L + E +     A  I+ L     SL  D
Sbjct: 344 PLHQKQSRITPIQKPRGLDPVEILQEREYRLQARIAHRIQELENLPGSLAGD 395



 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 73/257 (28%), Positives = 87/257 (33%), Gaps = 49/257 (19%)

Query: 462 PPQGGPPQPGPGP---QRQGPPLQQRPPPQGQQHLSGLG-----PPAGSPLPQRLPSPTS 513
           PP GG P+PGP P      G  L   P P      S +G     P AG P+P +   P  
Sbjct: 6   PPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQ--GPGG 63

Query: 514 APQQPASQAAPPTQG----------QGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQA 563
            PQ    Q   P +           +  Q + +    G      PP SP  Q   G P  
Sbjct: 64  YPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSP 123

Query: 564 TRQTS-VSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQ-AGPVPRTGPPTTQ-- 619
              +   S P P  ASG   G Q   GP   P   A P     Q  GP P       Q  
Sbjct: 124 LGGSEHASSPVP--ASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLR 181

Query: 620 ------------QPRPSGPGPA---GRPKPQLAQKPSQDVPPPATAAAGGPPHPQLNKSQ 664
                       QP P     A    RP P + Q+    +PPP+ +A G  P P      
Sbjct: 182 AQIMAYKMLARGQPLPDHLQMAVQGKRPMPGM-QQQMPTLPPPSVSATGPGPGPGPGPGP 240

Query: 665 SLTNAFNLPEPAPPRPS 681
                   P PAPP  S
Sbjct: 241 G-------PGPAPPNYS 250



 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 68/211 (32%), Positives = 83/211 (39%), Gaps = 35/211 (16%)

Query: 398 HQDEDKQLIVELVVNKM---AQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAG 454
           +Q++  QL  +++  KM    Q LP   Q          G+ P PG         Q P  
Sbjct: 173 NQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQ------GKRPMPG------MQQQMPTL 220

Query: 455 PP---AQQRPPPQGGP-PQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSP-LPQRLP 509
           PP   +   P P  GP P PGPGP    PP   RP   G  ++   GP    P +P + P
Sbjct: 221 PPPSVSATGPGPGPGPGPGPGPGP---APPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPP 277

Query: 510 S--PTSAPQQPASQAAPPTQGQGRQSRPVAGG--PGAPPAARPPASPSPQRQAGPPQATR 565
              P   P+ P + AA PT    +   P   G    APPA  P ASP       PPQ   
Sbjct: 278 GGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASP-----VMPPQT-- 330

Query: 566 QTSVSGPAPPKASGAPPGGQQRQGPPQKPPG 596
             S   PA P         Q R  P QKP G
Sbjct: 331 -QSPGQPAQPAPMVPLHQKQSRITPIQKPRG 360



 Score = 33.1 bits (74), Expect = 0.91
 Identities = 19/51 (37%), Positives = 23/51 (45%), Gaps = 7/51 (13%)

Query: 30 PPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAA------PSPGSSGGG 74
          P PP  G   PG +PGPG +      G +P  SP +      PSPG    G
Sbjct: 4  PDPPLGGTPRPGPSPGPGPSPG-AMLGPSPGPSPGSAHSMMGPSPGPPSAG 53



 Score = 33.1 bits (74), Expect = 0.91
 Identities = 19/53 (35%), Positives = 24/53 (45%), Gaps = 4/53 (7%)

Query: 28 PQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPG----SSGGGGF 76
          P+P P P    SPGA  GP    +  S+      SP  PS G    + G GG+
Sbjct: 12 PRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQGPGGY 64



 Score = 33.1 bits (74), Expect = 0.91
 Identities = 19/58 (32%), Positives = 22/58 (37%), Gaps = 7/58 (12%)

Query: 22  MTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAAS-------PAAPSPGSSG 72
           M  +Q+  P  PPP   + G  PGPG           P  S       P  P PG SG
Sbjct: 210 MPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSG 267



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 19/46 (41%), Positives = 24/46 (52%), Gaps = 2/46 (4%)

Query: 30  PPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGGG 75
           PPP P   HS G  P P    +E +S   PA+ P++    SSG GG
Sbjct: 108 PPPSPMDQHSQGY-PSP-LGGSEHASSPVPASGPSSGPQMSSGPGG 151


>gi|192807316 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform D [Homo sapiens]
          Length = 1616

 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 87/292 (29%), Positives = 105/292 (35%), Gaps = 36/292 (12%)

Query: 429 GRGSHGQTPSPGALPL-GRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPP 487
           G   H  +P P + P  G Q S  P G P     P   G    GP P  Q    Q R   
Sbjct: 125 GGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQI 184

Query: 488 QGQQHLSGLGPPAGSPLPQRLPSPTSAPQ-QPASQAAPPTQGQGRQSRPVAGGPGAPPAA 546
              + L+      G PLP  L       +  P  Q   PT      S   A GPG  P  
Sbjct: 185 MAYKMLA-----RGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVS---ATGPGPGPGP 236

Query: 547 RPPASPSPQRQAGPPQATRQTSVSGP--APPKASGAPPGGQQRQGPPQKPPGPAGPTRQA 604
            P   P P     PP  +R   + GP   PP  SG PPG      P Q P GP  P  + 
Sbjct: 237 GPGPGPGP----APPNYSRPHGMGGPNMPPPGPSGVPPG-----MPGQPPGGPPKPWPE- 286

Query: 605 SQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKP--SQDVPPPATAAAGGPPHP---- 658
              GP+     PT+   +   P P GRP P     P  +  V PP T + G P  P    
Sbjct: 287 ---GPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMV 343

Query: 659 QLNKSQSLTNAFNLPEPAPPRPSLSQDEVK-----AETIRSLRKSFASLFSD 705
            L++ QS       P    P   L + E +     A  I+ L     SL  D
Sbjct: 344 PLHQKQSRITPIQKPRGLDPVEILQEREYRLQARIAHRIQELENLPGSLAGD 395



 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 73/257 (28%), Positives = 87/257 (33%), Gaps = 49/257 (19%)

Query: 462 PPQGGPPQPGPGP---QRQGPPLQQRPPPQGQQHLSGLG-----PPAGSPLPQRLPSPTS 513
           PP GG P+PGP P      G  L   P P      S +G     P AG P+P +   P  
Sbjct: 6   PPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQ--GPGG 63

Query: 514 APQQPASQAAPPTQG----------QGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQA 563
            PQ    Q   P +           +  Q + +    G      PP SP  Q   G P  
Sbjct: 64  YPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSP 123

Query: 564 TRQTS-VSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQ-AGPVPRTGPPTTQ-- 619
              +   S P P  ASG   G Q   GP   P   A P     Q  GP P       Q  
Sbjct: 124 LGGSEHASSPVP--ASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLR 181

Query: 620 ------------QPRPSGPGPA---GRPKPQLAQKPSQDVPPPATAAAGGPPHPQLNKSQ 664
                       QP P     A    RP P + Q+    +PPP+ +A G  P P      
Sbjct: 182 AQIMAYKMLARGQPLPDHLQMAVQGKRPMPGM-QQQMPTLPPPSVSATGPGPGPGPGPGP 240

Query: 665 SLTNAFNLPEPAPPRPS 681
                   P PAPP  S
Sbjct: 241 G-------PGPAPPNYS 250



 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 68/211 (32%), Positives = 83/211 (39%), Gaps = 35/211 (16%)

Query: 398 HQDEDKQLIVELVVNKM---AQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAG 454
           +Q++  QL  +++  KM    Q LP   Q          G+ P PG         Q P  
Sbjct: 173 NQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQ------GKRPMPG------MQQQMPTL 220

Query: 455 PP---AQQRPPPQGGP-PQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSP-LPQRLP 509
           PP   +   P P  GP P PGPGP    PP   RP   G  ++   GP    P +P + P
Sbjct: 221 PPPSVSATGPGPGPGPGPGPGPGP---APPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPP 277

Query: 510 S--PTSAPQQPASQAAPPTQGQGRQSRPVAGG--PGAPPAARPPASPSPQRQAGPPQATR 565
              P   P+ P + AA PT    +   P   G    APPA  P ASP       PPQ   
Sbjct: 278 GGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASP-----VMPPQT-- 330

Query: 566 QTSVSGPAPPKASGAPPGGQQRQGPPQKPPG 596
             S   PA P         Q R  P QKP G
Sbjct: 331 -QSPGQPAQPAPMVPLHQKQSRITPIQKPRG 360



 Score = 33.1 bits (74), Expect = 0.91
 Identities = 19/51 (37%), Positives = 23/51 (45%), Gaps = 7/51 (13%)

Query: 30 PPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAA------PSPGSSGGG 74
          P PP  G   PG +PGPG +      G +P  SP +      PSPG    G
Sbjct: 4  PDPPLGGTPRPGPSPGPGPSPG-AMLGPSPGPSPGSAHSMMGPSPGPPSAG 53



 Score = 33.1 bits (74), Expect = 0.91
 Identities = 19/53 (35%), Positives = 24/53 (45%), Gaps = 4/53 (7%)

Query: 28 PQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPG----SSGGGGF 76
          P+P P P    SPGA  GP    +  S+      SP  PS G    + G GG+
Sbjct: 12 PRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQGPGGY 64



 Score = 33.1 bits (74), Expect = 0.91
 Identities = 19/58 (32%), Positives = 22/58 (37%), Gaps = 7/58 (12%)

Query: 22  MTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAAS-------PAAPSPGSSG 72
           M  +Q+  P  PPP   + G  PGPG           P  S       P  P PG SG
Sbjct: 210 MPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSG 267



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 19/46 (41%), Positives = 24/46 (52%), Gaps = 2/46 (4%)

Query: 30  PPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGGG 75
           PPP P   HS G  P P    +E +S   PA+ P++    SSG GG
Sbjct: 108 PPPSPMDQHSQGY-PSP-LGGSEHASSPVPASGPSSGPQMSSGPGG 151


>gi|192807314 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform C [Homo sapiens]
          Length = 1617

 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 87/292 (29%), Positives = 105/292 (35%), Gaps = 36/292 (12%)

Query: 429 GRGSHGQTPSPGALPL-GRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPP 487
           G   H  +P P + P  G Q S  P G P     P   G    GP P  Q    Q R   
Sbjct: 125 GGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQI 184

Query: 488 QGQQHLSGLGPPAGSPLPQRLPSPTSAPQ-QPASQAAPPTQGQGRQSRPVAGGPGAPPAA 546
              + L+      G PLP  L       +  P  Q   PT      S   A GPG  P  
Sbjct: 185 MAYKMLA-----RGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVS---ATGPGPGPGP 236

Query: 547 RPPASPSPQRQAGPPQATRQTSVSGP--APPKASGAPPGGQQRQGPPQKPPGPAGPTRQA 604
            P   P P     PP  +R   + GP   PP  SG PPG      P Q P GP  P  + 
Sbjct: 237 GPGPGPGP----APPNYSRPHGMGGPNMPPPGPSGVPPG-----MPGQPPGGPPKPWPE- 286

Query: 605 SQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKP--SQDVPPPATAAAGGPPHP---- 658
              GP+     PT+   +   P P GRP P     P  +  V PP T + G P  P    
Sbjct: 287 ---GPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMV 343

Query: 659 QLNKSQSLTNAFNLPEPAPPRPSLSQDEVK-----AETIRSLRKSFASLFSD 705
            L++ QS       P    P   L + E +     A  I+ L     SL  D
Sbjct: 344 PLHQKQSRITPIQKPRGLDPVEILQEREYRLQARIAHRIQELENLPGSLAGD 395



 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 73/257 (28%), Positives = 87/257 (33%), Gaps = 49/257 (19%)

Query: 462 PPQGGPPQPGPGP---QRQGPPLQQRPPPQGQQHLSGLG-----PPAGSPLPQRLPSPTS 513
           PP GG P+PGP P      G  L   P P      S +G     P AG P+P +   P  
Sbjct: 6   PPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQ--GPGG 63

Query: 514 APQQPASQAAPPTQG----------QGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQA 563
            PQ    Q   P +           +  Q + +    G      PP SP  Q   G P  
Sbjct: 64  YPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSP 123

Query: 564 TRQTS-VSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQ-AGPVPRTGPPTTQ-- 619
              +   S P P  ASG   G Q   GP   P   A P     Q  GP P       Q  
Sbjct: 124 LGGSEHASSPVP--ASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLR 181

Query: 620 ------------QPRPSGPGPA---GRPKPQLAQKPSQDVPPPATAAAGGPPHPQLNKSQ 664
                       QP P     A    RP P + Q+    +PPP+ +A G  P P      
Sbjct: 182 AQIMAYKMLARGQPLPDHLQMAVQGKRPMPGM-QQQMPTLPPPSVSATGPGPGPGPGPGP 240

Query: 665 SLTNAFNLPEPAPPRPS 681
                   P PAPP  S
Sbjct: 241 G-------PGPAPPNYS 250



 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 68/211 (32%), Positives = 83/211 (39%), Gaps = 35/211 (16%)

Query: 398 HQDEDKQLIVELVVNKM---AQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAG 454
           +Q++  QL  +++  KM    Q LP   Q          G+ P PG         Q P  
Sbjct: 173 NQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQ------GKRPMPG------MQQQMPTL 220

Query: 455 PP---AQQRPPPQGGP-PQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSP-LPQRLP 509
           PP   +   P P  GP P PGPGP    PP   RP   G  ++   GP    P +P + P
Sbjct: 221 PPPSVSATGPGPGPGPGPGPGPGP---APPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPP 277

Query: 510 S--PTSAPQQPASQAAPPTQGQGRQSRPVAGG--PGAPPAARPPASPSPQRQAGPPQATR 565
              P   P+ P + AA PT    +   P   G    APPA  P ASP       PPQ   
Sbjct: 278 GGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASP-----VMPPQT-- 330

Query: 566 QTSVSGPAPPKASGAPPGGQQRQGPPQKPPG 596
             S   PA P         Q R  P QKP G
Sbjct: 331 -QSPGQPAQPAPMVPLHQKQSRITPIQKPRG 360



 Score = 33.1 bits (74), Expect = 0.91
 Identities = 19/51 (37%), Positives = 23/51 (45%), Gaps = 7/51 (13%)

Query: 30 PPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAA------PSPGSSGGG 74
          P PP  G   PG +PGPG +      G +P  SP +      PSPG    G
Sbjct: 4  PDPPLGGTPRPGPSPGPGPSPG-AMLGPSPGPSPGSAHSMMGPSPGPPSAG 53



 Score = 33.1 bits (74), Expect = 0.91
 Identities = 19/53 (35%), Positives = 24/53 (45%), Gaps = 4/53 (7%)

Query: 28 PQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPG----SSGGGGF 76
          P+P P P    SPGA  GP    +  S+      SP  PS G    + G GG+
Sbjct: 12 PRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQGPGGY 64



 Score = 33.1 bits (74), Expect = 0.91
 Identities = 19/58 (32%), Positives = 22/58 (37%), Gaps = 7/58 (12%)

Query: 22  MTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAAS-------PAAPSPGSSG 72
           M  +Q+  P  PPP   + G  PGPG           P  S       P  P PG SG
Sbjct: 210 MPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSG 267



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 19/46 (41%), Positives = 24/46 (52%), Gaps = 2/46 (4%)

Query: 30  PPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGGG 75
           PPP P   HS G  P P    +E +S   PA+ P++    SSG GG
Sbjct: 108 PPPSPMDQHSQGY-PSP-LGGSEHASSPVPASGPSSGPQMSSGPGG 151


>gi|192807312 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform B [Homo sapiens]
          Length = 1647

 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 87/292 (29%), Positives = 105/292 (35%), Gaps = 36/292 (12%)

Query: 429 GRGSHGQTPSPGALPL-GRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPP 487
           G   H  +P P + P  G Q S  P G P     P   G    GP P  Q    Q R   
Sbjct: 125 GGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQI 184

Query: 488 QGQQHLSGLGPPAGSPLPQRLPSPTSAPQ-QPASQAAPPTQGQGRQSRPVAGGPGAPPAA 546
              + L+      G PLP  L       +  P  Q   PT      S   A GPG  P  
Sbjct: 185 MAYKMLA-----RGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVS---ATGPGPGPGP 236

Query: 547 RPPASPSPQRQAGPPQATRQTSVSGP--APPKASGAPPGGQQRQGPPQKPPGPAGPTRQA 604
            P   P P     PP  +R   + GP   PP  SG PPG      P Q P GP  P  + 
Sbjct: 237 GPGPGPGP----APPNYSRPHGMGGPNMPPPGPSGVPPG-----MPGQPPGGPPKPWPE- 286

Query: 605 SQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKP--SQDVPPPATAAAGGPPHP---- 658
              GP+     PT+   +   P P GRP P     P  +  V PP T + G P  P    
Sbjct: 287 ---GPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMV 343

Query: 659 QLNKSQSLTNAFNLPEPAPPRPSLSQDEVK-----AETIRSLRKSFASLFSD 705
            L++ QS       P    P   L + E +     A  I+ L     SL  D
Sbjct: 344 PLHQKQSRITPIQKPRGLDPVEILQEREYRLQARIAHRIQELENLPGSLAGD 395



 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 73/257 (28%), Positives = 87/257 (33%), Gaps = 49/257 (19%)

Query: 462 PPQGGPPQPGPGP---QRQGPPLQQRPPPQGQQHLSGLG-----PPAGSPLPQRLPSPTS 513
           PP GG P+PGP P      G  L   P P      S +G     P AG P+P +   P  
Sbjct: 6   PPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQ--GPGG 63

Query: 514 APQQPASQAAPPTQG----------QGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQA 563
            PQ    Q   P +           +  Q + +    G      PP SP  Q   G P  
Sbjct: 64  YPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSP 123

Query: 564 TRQTS-VSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQ-AGPVPRTGPPTTQ-- 619
              +   S P P  ASG   G Q   GP   P   A P     Q  GP P       Q  
Sbjct: 124 LGGSEHASSPVP--ASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLR 181

Query: 620 ------------QPRPSGPGPA---GRPKPQLAQKPSQDVPPPATAAAGGPPHPQLNKSQ 664
                       QP P     A    RP P + Q+    +PPP+ +A G  P P      
Sbjct: 182 AQIMAYKMLARGQPLPDHLQMAVQGKRPMPGM-QQQMPTLPPPSVSATGPGPGPGPGPGP 240

Query: 665 SLTNAFNLPEPAPPRPS 681
                   P PAPP  S
Sbjct: 241 G-------PGPAPPNYS 250



 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 68/211 (32%), Positives = 83/211 (39%), Gaps = 35/211 (16%)

Query: 398 HQDEDKQLIVELVVNKM---AQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAG 454
           +Q++  QL  +++  KM    Q LP   Q          G+ P PG         Q P  
Sbjct: 173 NQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQ------GKRPMPG------MQQQMPTL 220

Query: 455 PP---AQQRPPPQGGP-PQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSP-LPQRLP 509
           PP   +   P P  GP P PGPGP    PP   RP   G  ++   GP    P +P + P
Sbjct: 221 PPPSVSATGPGPGPGPGPGPGPGP---APPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPP 277

Query: 510 S--PTSAPQQPASQAAPPTQGQGRQSRPVAGG--PGAPPAARPPASPSPQRQAGPPQATR 565
              P   P+ P + AA PT    +   P   G    APPA  P ASP       PPQ   
Sbjct: 278 GGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASP-----VMPPQT-- 330

Query: 566 QTSVSGPAPPKASGAPPGGQQRQGPPQKPPG 596
             S   PA P         Q R  P QKP G
Sbjct: 331 -QSPGQPAQPAPMVPLHQKQSRITPIQKPRG 360



 Score = 33.1 bits (74), Expect = 0.91
 Identities = 19/51 (37%), Positives = 23/51 (45%), Gaps = 7/51 (13%)

Query: 30 PPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAA------PSPGSSGGG 74
          P PP  G   PG +PGPG +      G +P  SP +      PSPG    G
Sbjct: 4  PDPPLGGTPRPGPSPGPGPSPG-AMLGPSPGPSPGSAHSMMGPSPGPPSAG 53



 Score = 33.1 bits (74), Expect = 0.91
 Identities = 19/53 (35%), Positives = 24/53 (45%), Gaps = 4/53 (7%)

Query: 28 PQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPG----SSGGGGF 76
          P+P P P    SPGA  GP    +  S+      SP  PS G    + G GG+
Sbjct: 12 PRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQGPGGY 64



 Score = 33.1 bits (74), Expect = 0.91
 Identities = 19/58 (32%), Positives = 22/58 (37%), Gaps = 7/58 (12%)

Query: 22  MTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAAS-------PAAPSPGSSG 72
           M  +Q+  P  PPP   + G  PGPG           P  S       P  P PG SG
Sbjct: 210 MPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSG 267



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 19/46 (41%), Positives = 24/46 (52%), Gaps = 2/46 (4%)

Query: 30  PPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGGG 75
           PPP P   HS G  P P    +E +S   PA+ P++    SSG GG
Sbjct: 108 PPPSPMDQHSQGY-PSP-LGGSEHASSPVPASGPSSGPQMSSGPGG 151


>gi|21071056 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform B [Homo sapiens]
          Length = 1647

 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 87/292 (29%), Positives = 105/292 (35%), Gaps = 36/292 (12%)

Query: 429 GRGSHGQTPSPGALPL-GRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPP 487
           G   H  +P P + P  G Q S  P G P     P   G    GP P  Q    Q R   
Sbjct: 125 GGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQI 184

Query: 488 QGQQHLSGLGPPAGSPLPQRLPSPTSAPQ-QPASQAAPPTQGQGRQSRPVAGGPGAPPAA 546
              + L+      G PLP  L       +  P  Q   PT      S   A GPG  P  
Sbjct: 185 MAYKMLA-----RGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVS---ATGPGPGPGP 236

Query: 547 RPPASPSPQRQAGPPQATRQTSVSGP--APPKASGAPPGGQQRQGPPQKPPGPAGPTRQA 604
            P   P P     PP  +R   + GP   PP  SG PPG      P Q P GP  P  + 
Sbjct: 237 GPGPGPGP----APPNYSRPHGMGGPNMPPPGPSGVPPG-----MPGQPPGGPPKPWPE- 286

Query: 605 SQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKP--SQDVPPPATAAAGGPPHP---- 658
              GP+     PT+   +   P P GRP P     P  +  V PP T + G P  P    
Sbjct: 287 ---GPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMV 343

Query: 659 QLNKSQSLTNAFNLPEPAPPRPSLSQDEVK-----AETIRSLRKSFASLFSD 705
            L++ QS       P    P   L + E +     A  I+ L     SL  D
Sbjct: 344 PLHQKQSRITPIQKPRGLDPVEILQEREYRLQARIAHRIQELENLPGSLAGD 395



 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 73/257 (28%), Positives = 87/257 (33%), Gaps = 49/257 (19%)

Query: 462 PPQGGPPQPGPGP---QRQGPPLQQRPPPQGQQHLSGLG-----PPAGSPLPQRLPSPTS 513
           PP GG P+PGP P      G  L   P P      S +G     P AG P+P +   P  
Sbjct: 6   PPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQ--GPGG 63

Query: 514 APQQPASQAAPPTQG----------QGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQA 563
            PQ    Q   P +           +  Q + +    G      PP SP  Q   G P  
Sbjct: 64  YPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSP 123

Query: 564 TRQTS-VSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQ-AGPVPRTGPPTTQ-- 619
              +   S P P  ASG   G Q   GP   P   A P     Q  GP P       Q  
Sbjct: 124 LGGSEHASSPVP--ASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLR 181

Query: 620 ------------QPRPSGPGPA---GRPKPQLAQKPSQDVPPPATAAAGGPPHPQLNKSQ 664
                       QP P     A    RP P + Q+    +PPP+ +A G  P P      
Sbjct: 182 AQIMAYKMLARGQPLPDHLQMAVQGKRPMPGM-QQQMPTLPPPSVSATGPGPGPGPGPGP 240

Query: 665 SLTNAFNLPEPAPPRPS 681
                   P PAPP  S
Sbjct: 241 G-------PGPAPPNYS 250



 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 68/211 (32%), Positives = 83/211 (39%), Gaps = 35/211 (16%)

Query: 398 HQDEDKQLIVELVVNKM---AQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAG 454
           +Q++  QL  +++  KM    Q LP   Q          G+ P PG         Q P  
Sbjct: 173 NQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQ------GKRPMPG------MQQQMPTL 220

Query: 455 PP---AQQRPPPQGGP-PQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSP-LPQRLP 509
           PP   +   P P  GP P PGPGP    PP   RP   G  ++   GP    P +P + P
Sbjct: 221 PPPSVSATGPGPGPGPGPGPGPGP---APPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPP 277

Query: 510 S--PTSAPQQPASQAAPPTQGQGRQSRPVAGG--PGAPPAARPPASPSPQRQAGPPQATR 565
              P   P+ P + AA PT    +   P   G    APPA  P ASP       PPQ   
Sbjct: 278 GGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASP-----VMPPQT-- 330

Query: 566 QTSVSGPAPPKASGAPPGGQQRQGPPQKPPG 596
             S   PA P         Q R  P QKP G
Sbjct: 331 -QSPGQPAQPAPMVPLHQKQSRITPIQKPRG 360



 Score = 33.1 bits (74), Expect = 0.91
 Identities = 19/51 (37%), Positives = 23/51 (45%), Gaps = 7/51 (13%)

Query: 30 PPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAA------PSPGSSGGG 74
          P PP  G   PG +PGPG +      G +P  SP +      PSPG    G
Sbjct: 4  PDPPLGGTPRPGPSPGPGPSPG-AMLGPSPGPSPGSAHSMMGPSPGPPSAG 53



 Score = 33.1 bits (74), Expect = 0.91
 Identities = 19/53 (35%), Positives = 24/53 (45%), Gaps = 4/53 (7%)

Query: 28 PQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPG----SSGGGGF 76
          P+P P P    SPGA  GP    +  S+      SP  PS G    + G GG+
Sbjct: 12 PRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQGPGGY 64



 Score = 33.1 bits (74), Expect = 0.91
 Identities = 19/58 (32%), Positives = 22/58 (37%), Gaps = 7/58 (12%)

Query: 22  MTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAAS-------PAAPSPGSSG 72
           M  +Q+  P  PPP   + G  PGPG           P  S       P  P PG SG
Sbjct: 210 MPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSG 267



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 19/46 (41%), Positives = 24/46 (52%), Gaps = 2/46 (4%)

Query: 30  PPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGGG 75
           PPP P   HS G  P P    +E +S   PA+ P++    SSG GG
Sbjct: 108 PPPSPMDQHSQGY-PSP-LGGSEHASSPVPASGPSSGPQMSSGPGG 151


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 88/295 (29%), Positives = 107/295 (36%), Gaps = 44/295 (14%)

Query: 424  RDASPG-RGSHGQTPSPGAL-PLGRQTSQQPAGPPAQQRPPPQGGP-------------- 467
            +D  PG  G+ G   SPG   P G        G P  Q PP   GP              
Sbjct: 901  KDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAG 960

Query: 468  PQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQ 527
            P   PGP R  P  Q      G+   +GL    G P PQ LP       +P     P + 
Sbjct: 961  PPGMPGP-RGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSD 1019

Query: 528  GQ--------GRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASG 579
            G         G+  R   G PGAP A   P  P P    GP   +     SGPA P  + 
Sbjct: 1020 GLPGRDGSPGGKGDRGENGSPGAPGA---PGHPGPPGPVGPAGKSGDRGESGPAGPAGAP 1076

Query: 580  APPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGR------PK 633
             P G +   G PQ P G  G T +   AG     G P      P  PGPAG+      P 
Sbjct: 1077 GPAGSRGAPG-PQGPRGDKGETGERGAAGIKGHRGFP-GNPGAPGSPGPAGQQGAIGSPG 1134

Query: 634  PQLAQKPSQDVPPPATAAAG------GPPHPQLNKSQ--SLTNAFNLPEPAPPRP 680
            P   + P     PP            GPP P+ N+ +  S  +  +  +P PP P
Sbjct: 1135 PAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGP 1189



 Score = 80.5 bits (197), Expect = 5e-15
 Identities = 105/367 (28%), Positives = 121/367 (32%), Gaps = 107/367 (29%)

Query: 419 PRQRQRDASPGR-GSHGQTPSPGAL-PLGRQTSQQPAGPPAQQR----PPPQGGPPQPGP 472
           P  R    SPG  GS G+   PG+    GR     P+GP  Q      P P+G    PG 
Sbjct: 533 PGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGK 592

Query: 473 GPQRQGP--PLQQRPP-------PQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAA 523
             +R GP  P  Q PP       PQG    +G G   G   P   P P      P +   
Sbjct: 593 NGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGP---PGPQGLQGLPGTGGP 649

Query: 524 PPTQGQGRQSRPV--AGGPGAP--------PAARPP----ASPSPQRQAGPPQATRQTSV 569
           P   G+  +  P   AG PGAP        P  R P     +P  +  AGPP        
Sbjct: 650 PGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGA 709

Query: 570 SG-PAPPKASGAP-----------------------PGGQQRQGPPQK-----PPGPAGP 600
           +G P PP A+G P                       PGG    G P K     P GP GP
Sbjct: 710 AGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGP 769

Query: 601 TRQASQAGPV-------------PR--------TGPP--------TTQQPRPSGPGPAGR 631
              A Q G               PR        TGPP          Q   P G G  G 
Sbjct: 770 PGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGA 829

Query: 632 PKPQLAQKPSQDVPPPATAAAGGPPHPQLNKSQ----------SLTNAFNLP-------E 674
           P  +    P     PP  +   GPP PQ  K +              A  LP        
Sbjct: 830 PGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGN 889

Query: 675 PAPPRPS 681
           P PP PS
Sbjct: 890 PGPPGPS 896



 Score = 77.4 bits (189), Expect = 4e-14
 Identities = 75/246 (30%), Positives = 87/246 (35%), Gaps = 32/246 (13%)

Query: 415 AQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPG-PG 473
           A  LP       SPG       P P   P          G P Q   P  GG  + G PG
Sbjct: 784 APGLPGIAGPRGSPGERGETGPPGPAGFP----------GAPGQNGEP--GGKGERGAPG 831

Query: 474 PQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQS 533
            + +G P     PP G    SG   PAG P PQ +     +P  P +   P    +G   
Sbjct: 832 EKGEGGPPGVAGPPGG----SG---PAGPPGPQGVKGERGSPGGPGAAGFP--GARGLPG 882

Query: 534 RPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQK 593
            P + G   PP   P  SP      GP   T      G + PK     PG +   G  Q 
Sbjct: 883 PPGSNGNPGPPG--PSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPG-AQG 939

Query: 594 PPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAG 653
           PPG  GP   A   G     GP       P  PGP G P PQ  +  S        +   
Sbjct: 940 PPGAPGPLGIAGITGARGLAGP-------PGMPGPRGSPGPQGVKGESGKPGANGLSGER 992

Query: 654 GPPHPQ 659
           GPP PQ
Sbjct: 993 GPPGPQ 998



 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 93/334 (27%), Positives = 115/334 (34%), Gaps = 91/334 (27%)

Query: 415 AQALPRQRQRDASPG-RGSHGQTPSPGALPLGRQTSQQPAGPP-AQQRPPPQGGPPQPG- 471
           AQ  P     + SPG +G  G    PGA   G   ++ P GP  A   P  +GG  +PG 
Sbjct: 379 AQGPPGPPGINGSPGGKGEMGPAGIPGAP--GLMGARGPPGPAGANGAPGLRGGAGEPGK 436

Query: 472 ------PGPQRQG-----------------------PPLQQRPPPQGQQHLSGLGPPAGS 502
                 PGP+ +                        P     P   G++   G   PAG 
Sbjct: 437 NGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAG- 495

Query: 503 PLPQRLPSPTS-APQQPASQAAPPTQGQGRQSRP-VAGGPGAPPAARPPASPSPQRQAGP 560
             P  +P     A ++ A   A P    G   R  V GGPG       P  P    + GP
Sbjct: 496 --PNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGP 553

Query: 561 PQATRQTSVSGPAPPKA----------------SGAP--------PGGQQRQGP------ 590
           P +  ++   GP  P                   GAP        PGG   QGP      
Sbjct: 554 PGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGE 613

Query: 591 --PQKPPGPAGPTRQASQAGP--------VPRTGPPTTQQPRPSGPGP---AGRPKPQ-- 635
             PQ PPGP GP       GP        +P TG P  +  +P  PGP   AG P     
Sbjct: 614 TGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGG 673

Query: 636 --LAQKPSQDVPPPATAAAG-----GPPHPQLNK 662
              A  P +  PP    A G     GPP P+  K
Sbjct: 674 KGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGK 707



 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 88/305 (28%), Positives = 107/305 (35%), Gaps = 72/305 (23%)

Query: 416 QALPRQRQRDASPG-RGSHGQTPSPGALPL-GRQTSQQPAGPPAQQRPPPQGGPPQPGPG 473
           Q +P +R    SPG +G  G+   PGA  + G+   + P GP     P P G P   G G
Sbjct: 725 QGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGP--PGPAGQPGDKGEG 782

Query: 474 PQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRL---PSPTSAPQQPASQAAPPTQGQG 530
                          G   L G+  P GSP  +     P P   P  P     P   G+G
Sbjct: 783 ---------------GAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPG--GKG 825

Query: 531 RQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKAS-GAP-------- 581
            +  P   G G PP             AGPP  +      GP   K   G+P        
Sbjct: 826 ERGAPGEKGEGGPPGV-----------AGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGF 874

Query: 582 PGGQQRQGPPQK-----PPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGP-GPAGRP--- 632
           PG +   GPP       PPGP+G   +    GP   TG P +  P  SGP G AG+P   
Sbjct: 875 PGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGS--PGVSGPKGDAGQPGEK 932

Query: 633 -KPQLAQKPSQDVP--------------PPATAAAGGPPHPQLNKSQSLTNAFN--LPEP 675
             P     P    P              PP      G P PQ  K +S     N    E 
Sbjct: 933 GSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGER 992

Query: 676 APPRP 680
            PP P
Sbjct: 993 GPPGP 997



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 79/301 (26%), Positives = 96/301 (31%), Gaps = 82/301 (27%)

Query: 435 QTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPP----QPGPGPQRQGPPLQQRPPPQGQ 490
           Q P+    P   Q  Q P G P     P + G P    QPG  P   GPP      P G 
Sbjct: 90  QPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPG-SPGSPGPPGICESCPTGP 148

Query: 491 QH------------------LSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQ 532
           Q+                  L+G   PAG P P   P  +  P  P S       G+  Q
Sbjct: 149 QNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQ 208

Query: 533 SRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGP----APPKASGAP------- 581
           + P +G PG P A  P        ++G P    +  + GP     P    G P       
Sbjct: 209 AGP-SGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRG 267

Query: 582 -------------PGGQQRQGPPQK--PPGPAGPTRQASQAGPVPRTGPP---------- 616
                        PG +   G P +   PGP GP     + G   R G P          
Sbjct: 268 FDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERG---RPGLPGAAGARGNDG 324

Query: 617 ---TTQQPRPSGP----------------GPAGRPKPQLAQKPSQDVPPPATAAAGGPPH 657
              +  QP P GP                GPAG P    A     +  P   A A GPP 
Sbjct: 325 ARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPG 384

Query: 658 P 658
           P
Sbjct: 385 P 385



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 67/225 (29%), Positives = 78/225 (34%), Gaps = 33/225 (14%)

Query: 416  QALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPG-PGP 474
            Q LP        PGR  +   P    LP GR  S    G   +   P  G P  PG PGP
Sbjct: 998  QGLPGLAGTAGEPGRDGN---PGSDGLP-GRDGSPGGKGDRGENGSP--GAPGAPGHPGP 1051

Query: 475  QRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQG--RQ 532
                      P P G    SG    +G   P   P P  +   P  Q     +G+   R 
Sbjct: 1052 ----------PGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERG 1101

Query: 533  SRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPK---ASGAPPGGQQRQG 589
            +  + G  G P     P SP P  Q G           GPA P+       PPG     G
Sbjct: 1102 AAGIKGHRGFPGNPGAPGSPGPAGQQGA------IGSPGPAGPRGPVGPSGPPGKDGTSG 1155

Query: 590  PPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKP 634
             P  P GP GP     + G     G P     +P  PGP G P P
Sbjct: 1156 HP-GPIGPPGPRGNRGERGSEGSPGHP----GQPGPPGPPGAPGP 1195



 Score = 60.1 bits (144), Expect = 7e-09
 Identities = 74/267 (27%), Positives = 86/267 (32%), Gaps = 41/267 (15%)

Query: 437 PSPGALPLGRQTSQQPAGPPAQQRPP-------PQGGPPQPGPGPQRQGPPLQQRPPPQG 489
           P P   P      Q P GP     PP         G P QPG  P   GPP      P G
Sbjct: 89  PQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPG-SPGSPGPPGICESCPTG 147

Query: 490 QQHLS------------GLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVA 537
            Q+ S             +G  AG P P   P P   P       +P + G         
Sbjct: 148 PQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGY-------Q 200

Query: 538 GGPGAPPAARPPASPSPQRQAGPPQATRQTSVSG-PAPPKASGAPPGGQQRQGPPQKP-- 594
           G PG P  A P   P P    GP     +   SG P  P   G  PG    +GP   P  
Sbjct: 201 GPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGL-PGPPGIKGPAGIPGF 259

Query: 595 PGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQ-KPSQDVPPPATAAAG 653
           PG  G      + G    TG P  +      PG  G P P   +  P +   P    AAG
Sbjct: 260 PGMKGHRGFDGRNGEKGETGAPGLKGEN-GLPGENGAPGPMGPRGAPGERGRPGLPGAAG 318

Query: 654 GPPHPQLNKSQSLTNAFNLPEPAPPRP 680
              +     S          +P PP P
Sbjct: 319 ARGNDGARGSDG--------QPGPPGP 337



 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 64/208 (30%), Positives = 75/208 (36%), Gaps = 37/208 (17%)

Query: 437 PSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGL 496
           P+P  +P G   +  P  P A  RPP   GP  P   P   GPP    P   G   + G 
Sbjct: 75  PNP-EIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDP---GPP--GIPGRNGDPGIPGQ 128

Query: 497 GPPAGSPLPQRL--PSPTS----APQQPASQAAPPTQGQGRQSRPVAGGPGAPPA----A 546
               GSP P  +    PT     +PQ  +          G    P   GP  PP     +
Sbjct: 129 PGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTS 188

Query: 547 RPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQ 606
             P SP      GPP    Q   SG         PPG          PPG  GP+  A +
Sbjct: 189 GHPGSPGSPGYQGPPGEPGQAGPSG---------PPG----------PPGAIGPSGPAGK 229

Query: 607 AGPVPRTGPPTTQ-QPRPSG-PGPAGRP 632
            G   R G P  +  P P G  GPAG P
Sbjct: 230 DGESGRPGRPGERGLPGPPGIKGPAGIP 257



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 78/300 (26%), Positives = 93/300 (31%), Gaps = 77/300 (25%)

Query: 428 PGRGSHGQTP-SPGAL-PLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRP 485
           PG   H  +P SPG   P G      P+GPP    PP   GP  P       G P   RP
Sbjct: 185 PGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPG---PPGAIGPSGPAGKDGESGRP--GRP 239

Query: 486 PPQGQQHLSGLGPPAGSP-LP--------------------------QRLPSPTSAPQQP 518
             +G     G+  PAG P  P                            LP    AP   
Sbjct: 240 GERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPM 299

Query: 519 ASQAAPPTQGQ--------------GRQSRPVAGGPGAPPAARPPASPSPQRQAGP---- 560
             + AP  +G+               R S    G PG P  A  P SP  + + GP    
Sbjct: 300 GPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSP 359

Query: 561 -----------PQATRQTSVSGPAPPKASGAPPGGQQRQGP-----------PQKPPGPA 598
                      P         GP  P      PGG+   GP            + PPGPA
Sbjct: 360 GSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPA 419

Query: 599 GPTRQASQAGPVPRTGPPTTQ-QPRPSGP-GPAGRP-KPQLAQKPSQDVPPPATAAAGGP 655
           G        G     G    + +P P G  G AG P  P    +  +D  P    A G P
Sbjct: 420 GANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLP 479



 Score = 33.1 bits (74), Expect = 0.91
 Identities = 29/87 (33%), Positives = 33/87 (37%), Gaps = 10/87 (11%)

Query: 34  PPGAHSPGATPGPGTATAERSSGVAPAAS--PAAPS----PGSSGGGGFFSSLSNAVKQT 87
           PPG   P   PGP     ER S   P A+  P A      PGS+G  G      +  K  
Sbjct: 844 PPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDG 903

Query: 88  TAAAA----ATFSEQVGGGSGGAGRGG 110
               A    A  S  V G  G AG+ G
Sbjct: 904 PPGPAGNTGAPGSPGVSGPKGDAGQPG 930



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 31/110 (28%), Positives = 40/110 (36%), Gaps = 26/110 (23%)

Query: 27  RPQPPPPP--------PGAH-------SPGATPGPGTATAERSSGVAPAASPAAPSPGSS 71
           +P PP PP        PGA        SPG+   PG        G A A  P  P PG +
Sbjct: 331 QPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGP-PGIN 389

Query: 72  GGGGFFSSLSNA----------VKQTTAAAAATFSEQVGGGSGGAGRGGA 111
           G  G    +  A           +     A A  +  + GG+G  G+ GA
Sbjct: 390 GSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGA 439



 Score = 32.0 bits (71), Expect = 2.0
 Identities = 19/56 (33%), Positives = 23/56 (41%), Gaps = 1/56 (1%)

Query: 20  GYMTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGGG 75
           GY      P PP PP  +  PG+   PG        G A  + P  P PG+ G  G
Sbjct: 171 GYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGP-PGAIGPSG 225



 Score = 30.4 bits (67), Expect = 5.9
 Identities = 20/54 (37%), Positives = 22/54 (40%), Gaps = 5/54 (9%)

Query: 27  RPQPPPPPPGAHSPGATPGPGTATAERSSGV-----APAASPAAPSPGSSGGGG 75
           +P  P P   A +PGA  G G A A    G      AP     A  PG  GG G
Sbjct: 655 KPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKG 708


>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
            1 [Homo sapiens]
          Length = 1250

 Score = 86.7 bits (213), Expect = 7e-17
 Identities = 93/335 (27%), Positives = 122/335 (36%), Gaps = 56/335 (16%)

Query: 422  RQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPG-------P 474
            R ++AS   G+  + P+P  +   +    Q   PP    PPP   PP P PG       P
Sbjct: 672  RLQNASQHSGALFKPPTPPVMQ-SQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKP 730

Query: 475  QRQGPPLQQ--RPPPQGQ----QHLSGLGPPAGSPLPQ-RLPSPTSAPQQPASQAAPPTQ 527
                P L Q   PPP  +    QH++ + PP   P P    P P  AP +P      PT 
Sbjct: 731  APCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTS 790

Query: 528  GQG-----RQSRPVAGGPGAPPAAR---------PPASPSPQRQAGPPQATRQTSVSGPA 573
             +       Q+ P    P  PPA +         PP+ P+P     PP   +Q S     
Sbjct: 791  TKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKP 850

Query: 574  PPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRT----GPPTTQQ--------- 620
            PP      P    +Q   Q PP P  P  ++    PVP       PP  +          
Sbjct: 851  PPSPLSPVPS-VVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSI 909

Query: 621  --PRPSGPGPAGR-----PKPQLAQKPSQDVPPPATAAA----GGPPHPQLNKSQSLTNA 669
              P P  P P        P P  +  P+   PPP TA+      G P  + +K+ S    
Sbjct: 910  PVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGG- 968

Query: 670  FNLPEPAPPRPSLSQDEVKAETIRSLRKSFASLFS 704
               P P P R S  +    AE     R S  SL S
Sbjct: 969  -KKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVS 1002



 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 81/280 (28%), Positives = 97/280 (34%), Gaps = 61/280 (21%)

Query: 439 PGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPP----------- 487
           P   P  +  +   A  P+   PPP   PP P P P    PPL  +  P           
Sbjct: 607 PPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVK 666

Query: 488 --------QGQQHLSGLGPPAGSPL-------PQRLPSPTSAPQQPASQAAPPTQGQG-R 531
                      QH   L  P   P+       PQ L  P      P     PPT G    
Sbjct: 667 YSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMA 726

Query: 532 QSRPVAGGPGAPPAARPPASPSPQRQAGPP----QATRQTSVSGPAPPKASGAPPGGQQR 587
           Q +P    P  P  + PP          PP    Q    T V+ P PP     PP     
Sbjct: 727 QLKPAPCAPSLPQFSAPP----------PPLKIHQVQHITQVAPPTPP-----PPPPIPA 771

Query: 588 QGPPQKPPGP----AGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQD 643
             PPQ PP P      PT   + A  V +  PPT     P+ P P  + +P     P+  
Sbjct: 772 PLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPT-----PTPPVPPAKKQPAF---PASY 823

Query: 644 VPP-PATAAAGGPPHPQLNKSQSLTNAFNLPEPAPPRPSL 682
           +PP P T     PP P L K QS   A   P P  P PS+
Sbjct: 824 IPPSPPTPPVPVPP-PTLPKQQSFC-AKPPPSPLSPVPSV 861



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 64/258 (24%), Positives = 90/258 (34%), Gaps = 45/258 (17%)

Query: 436  TPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQ--------RQGPPLQQRPPP 487
            TP+P   P      +QPA P A   PP    PP P P P          + PP    P P
Sbjct: 805  TPTPPVPP----AKKQPAFP-ASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVP 859

Query: 488  QGQQHLSGLGPPAGSP---------------LPQRLPSPTSAPQ-QPAS--------QAA 523
               + ++   PP  +P                PQ  P+  + P+ QP+S           
Sbjct: 860  SVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPP 919

Query: 524  PPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSG----PAPPKASG 579
            PP         P +  P  PP   P ASP+P +   P + T +TS  G    P  P+ + 
Sbjct: 920  PPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNS 979

Query: 580  APPGGQQRQGPPQKPPG----PAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQ 635
            +       + P  K P      +  T  A    P   T PP    P+P     +G   P 
Sbjct: 980  SIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPG 1039

Query: 636  LAQKPSQDVPPPATAAAG 653
            + Q+       P  +  G
Sbjct: 1040 VLQQGCVSAKAPVLSGRG 1057



 Score = 56.6 bits (135), Expect = 8e-08
 Identities = 51/193 (26%), Positives = 68/193 (35%), Gaps = 17/193 (8%)

Query: 501 GSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGP 560
           G+ L +   +   +  +P +   PP   Q +   P      +PP   PP  P P     P
Sbjct: 584 GTQLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPP 643

Query: 561 PQATRQTSVSGPAPPKASGAP-----------PGGQQRQGPPQKPPGPAGPTRQASQAGP 609
           P      S S  AP   S AP               Q  G   KPP P  P  Q+    P
Sbjct: 644 PPPPPLPSQS--APSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTP--PVMQSQSVKP 699

Query: 610 VPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLNKSQSLTN- 668
                PP    P P  P P   P   +AQ       P     +  PP  ++++ Q +T  
Sbjct: 700 QILV-PPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQV 758

Query: 669 AFNLPEPAPPRPS 681
           A   P P PP P+
Sbjct: 759 APPTPPPPPPIPA 771



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 79/316 (25%), Positives = 109/316 (34%), Gaps = 74/316 (23%)

Query: 437  PSPGALPLGRQTSQQ-PAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQ----------RP 485
            PSP   P   ++S   P  PP+    PP   PP   P P + G P ++          +P
Sbjct: 912  PSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKP 971

Query: 486  PPQGQQH----------------------LSGLGPPA--GSPLPQRLPSPTSAP------ 515
            PP  Q++                      +S   PPA  GSP  + LP P + P      
Sbjct: 972  PPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLN 1031

Query: 516  -----------QQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQAT 564
                       Q   S  AP   G+G+ S  V   P +PP+      P P+ +   P   
Sbjct: 1032 LSGVNLPGVLQQGCVSAKAPVLSGRGKDS--VVEFP-SPPSDSDFPPPPPETELPLPPIE 1088

Query: 565  RQTSVSGPAPPKASGAPPGGQQ-RQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRP 623
                 SG   PK +   P  QQ  +   +K P P  P R  S       T    ++QP  
Sbjct: 1089 IPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDS----TRLTQAEISEQPTM 1144

Query: 624  SGPGPAGRPKPQLAQKPSQDVPPPATAAAGGP-PHPQLNKSQSLTNAFNLPEPA------ 676
            +   P     P    K S  V P   A          + +  SL++  +  EP       
Sbjct: 1145 ATVVPQVPTSP----KSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDDM 1200

Query: 677  ---PPRPSLSQDEVKA 689
               PP P L  D+ KA
Sbjct: 1201 ALPPPPPELLSDQQKA 1216



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 44/152 (28%), Positives = 54/152 (35%), Gaps = 34/152 (22%)

Query: 548 PPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQA 607
           PP SP P+     P    Q S   P PP     PP       PP  PP P  P++ A  A
Sbjct: 607 PPLSPQPKIVT--PYTASQPSPPLPPPPPPPPPPP-------PPPPPPPPPLPSQSAPSA 657

Query: 608 GPVP----RTGPPTTQQPRPSGPGPAGRP-----------KPQLAQKPSQDVPPPATAAA 652
           G       +    T  Q      G   +P           KPQ+   P+  VPPP     
Sbjct: 658 GSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPP---- 713

Query: 653 GGPPHPQLNKSQSLTNAFNLPEPAPPRPSLSQ 684
             PP P      ++       +PAP  PSL Q
Sbjct: 714 --PPPPPPTPGSAMAQL----KPAPCAPSLPQ 739



 Score = 34.3 bits (77), Expect = 0.41
 Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 2/49 (4%)

Query: 28  PQPPPPPPGAHSPGATPGPGTATAERSS--GVAPAASPAAPSPGSSGGG 74
           P PPPPP  + +P  +  PG  T++ SS  G  P  +P   S   S  G
Sbjct: 938 PPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSG 986



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 31/102 (30%), Positives = 38/102 (37%), Gaps = 18/102 (17%)

Query: 590 PPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPAT 649
           PP  P         ASQ  P P   PP    P P  P P   P P L   PSQ  P   +
Sbjct: 607 PPLSPQPKIVTPYTASQPSP-PLPPPPPPPPPPPPPPPP---PPPPL---PSQSAPSAGS 659

Query: 650 AAAGGPPHPQLNKSQSLTNAFNLPEPA-----PPRPSLSQDE 686
           AA      P   K  ++T   N  + +     PP P + Q +
Sbjct: 660 AA------PMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQ 695



 Score = 31.2 bits (69), Expect = 3.4
 Identities = 16/40 (40%), Positives = 18/40 (45%)

Query: 27  RPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAP 66
           +P PP PPP    P   P P        S  AP+A  AAP
Sbjct: 623 QPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAP 662



 Score = 30.4 bits (67), Expect = 5.9
 Identities = 19/50 (38%), Positives = 24/50 (48%), Gaps = 4/50 (8%)

Query: 21  YMTDLQRPQPPPPP--PGAHSPGATPGPGTATAERSS--GVAPAASPAAP 66
           ++T +  P PPPPP  P    P A P P       +S   VAP  + AAP
Sbjct: 754 HITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAP 803


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.131    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,054,707
Number of Sequences: 37866
Number of extensions: 3433090
Number of successful extensions: 94795
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1192
Number of HSP's successfully gapped in prelim test: 3175
Number of HSP's that attempted gapping in prelim test: 20684
Number of HSP's gapped (non-prelim): 34815
length of query: 705
length of database: 18,247,518
effective HSP length: 109
effective length of query: 596
effective length of database: 14,120,124
effective search space: 8415593904
effective search space used: 8415593904
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.