Guide to the Human Genome
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Search of human proteins with 19923973

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19923973 potassium channel tetramerisation domain containing
12 [Homo sapiens]
         (325 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19923973 potassium channel tetramerisation domain containing ...   660   0.0  
gi|38198663 potassium channel tetramerisation domain containing ...   315   5e-86
gi|55926200 potassium channel tetramerisation domain containing ...   315   5e-86
gi|71143104 potassium channel tetramerisation domain containing ...    88   9e-18
gi|189571693 potassium channel tetramerisation domain containing...    85   8e-17
gi|189571691 potassium channel tetramerisation domain containing...    85   8e-17
gi|194018443 potassium channel tetramerisation domain containing...    79   7e-15
gi|194018441 potassium channel tetramerisation domain containing...    79   7e-15
gi|194018439 potassium channel tetramerisation domain containing...    79   7e-15
gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]       75   8e-14
gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]       75   8e-14
gi|146198864 potassium channel tetramerisation domain containing...    72   5e-13
gi|218505694 potassium channel tetramerisation domain containing...    72   7e-13
gi|209969708 potassium channel tetramerisation domain containing...    72   7e-13
gi|40217617 potassium channel tetramerisation domain containing ...    72   7e-13
gi|45387953 potassium channel tetramerization domain containing ...    68   1e-11
gi|142356950 potassium channel tetramerisation domain containing...    65   1e-10
gi|23308551 potassium channel tetramerisation domain containing ...    62   5e-10
gi|53829365 potassium channel tetramerisation domain containing ...    62   9e-10
gi|9506651 potassium channel tetramerisation domain containing 5...    59   4e-09
gi|46255026 potassium channel tetramerisation domain containing ...    56   5e-08
gi|39753959 potassium channel tetramerisation domain containing ...    56   5e-08
gi|169234778 potassium channel tetramerisation domain containing...    54   2e-07
gi|13994353 potassium channel tetramerisation domain containing ...    54   2e-07
gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]                  53   3e-07
gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo...    52   9e-07
gi|30578412 potassium channel tetramerisation domain containing ...    49   5e-06
gi|51036594 potassium channel tetramerisation domain containing ...    49   6e-06
gi|169184031 PREDICTED: similar to potassium channel tetramerisa...    48   1e-05
gi|169179790 PREDICTED: similar to potassium channel tetramerisa...    48   1e-05

>gi|19923973 potassium channel tetramerisation domain containing 12
           [Homo sapiens]
          Length = 325

 Score =  660 bits (1704), Expect = 0.0
 Identities = 325/325 (100%), Positives = 325/325 (100%)

Query: 1   MALADSTRGLPNGGGGGGGSGSSSSSAEPPLFPDIVELNVGGQVYVTRRCTVVSVPDSLL 60
           MALADSTRGLPNGGGGGGGSGSSSSSAEPPLFPDIVELNVGGQVYVTRRCTVVSVPDSLL
Sbjct: 1   MALADSTRGLPNGGGGGGGSGSSSSSAEPPLFPDIVELNVGGQVYVTRRCTVVSVPDSLL 60

Query: 61  WRMFTQQQPQELARDSKGRFFLDRDGFLFRYILDYLRDLQLVLPDYFPERSRLQREAEYF 120
           WRMFTQQQPQELARDSKGRFFLDRDGFLFRYILDYLRDLQLVLPDYFPERSRLQREAEYF
Sbjct: 61  WRMFTQQQPQELARDSKGRFFLDRDGFLFRYILDYLRDLQLVLPDYFPERSRLQREAEYF 120

Query: 121 ELPELVRRLGAPQQPGPGPPPSRRGVHKEGSLGDELLPLGYSEPEQQEGASAGAPSPTLE 180
           ELPELVRRLGAPQQPGPGPPPSRRGVHKEGSLGDELLPLGYSEPEQQEGASAGAPSPTLE
Sbjct: 121 ELPELVRRLGAPQQPGPGPPPSRRGVHKEGSLGDELLPLGYSEPEQQEGASAGAPSPTLE 180

Query: 181 LASRSPSGGAAGPLLTPSQSLDGSRRSGYITIGYRGSYTIGRDAQADAKFRRVARITVCG 240
           LASRSPSGGAAGPLLTPSQSLDGSRRSGYITIGYRGSYTIGRDAQADAKFRRVARITVCG
Sbjct: 181 LASRSPSGGAAGPLLTPSQSLDGSRRSGYITIGYRGSYTIGRDAQADAKFRRVARITVCG 240

Query: 241 KTSLAKEVFGDTLNESRDPDRPPERYTSRYYLKFNFLEQAFDKLSESGFHMVACSSTGTC 300
           KTSLAKEVFGDTLNESRDPDRPPERYTSRYYLKFNFLEQAFDKLSESGFHMVACSSTGTC
Sbjct: 241 KTSLAKEVFGDTLNESRDPDRPPERYTSRYYLKFNFLEQAFDKLSESGFHMVACSSTGTC 300

Query: 301 AFASSTDQSEDKIWTSYTEYVFCRE 325
           AFASSTDQSEDKIWTSYTEYVFCRE
Sbjct: 301 AFASSTDQSEDKIWTSYTEYVFCRE 325


>gi|38198663 potassium channel tetramerisation domain containing 8
           [Homo sapiens]
          Length = 473

 Score =  315 bits (806), Expect = 5e-86
 Identities = 172/323 (53%), Positives = 213/323 (65%), Gaps = 43/323 (13%)

Query: 17  GGGSGSSSSSAEPPLFPDIVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQ------ 70
           G  + ++     P  FP++VELNVGGQVYVT+  T++SVPDS L  MF+   P+      
Sbjct: 27  GASAAAAPGPCAPSPFPEVVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRR 86

Query: 71  -ELARDSKGRFFLDRDGFLFRYILDYLRDLQLVLPDYFPERSRLQREAEYFELPELVRRL 129
            EL RDS+ RFF+DRDGFLFRY+LDYLRD QL LP++FPE+ RL REAEYF+L +LV+ L
Sbjct: 87  GELPRDSRARFFIDRDGFLFRYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLL 146

Query: 130 GAPQQPGPGPPPSRRGVHKEGSLGDE--------LLPLGYSEPEQQEGASAGAPSPTLEL 181
                           V K+ SL DE         +  G S+     GA+A  PS     
Sbjct: 147 SPK-------------VTKQNSLNDEGCQSDLEDNVSQGSSDALLLRGAAAAVPS----- 188

Query: 182 ASRSPSGGAAGPLLTPSQSLDGSRRSGYITIGYRGSYTIGRDAQADAKFRRVARITVCGK 241
              +  GG  G            +RSG++T+GYRGSYT  RD QADAKFRRVARI VCG+
Sbjct: 189 GPGAHGGGGGGGAQ--------DKRSGFLTLGYRGSYTTVRDNQADAKFRRVARIMVCGR 240

Query: 242 TSLAKEVFGDTLNESRDPDRPPERYTSRYYLKFNFLEQAFDKLSESGFHMVACSSTGTCA 301
            +LAKEVFGDTLNESRDPDR PE+YTSR+YLKF +LEQAFD+LSE+GFHMVAC+S+GT A
Sbjct: 241 IALAKEVFGDTLNESRDPDRQPEKYTSRFYLKFTYLEQAFDRLSEAGFHMVACNSSGTAA 300

Query: 302 FASSTDQSEDKIWTSYTEYVFCR 324
           F +     +DKIW+SYTEY+F R
Sbjct: 301 FVN--QYRDDKIWSSYTEYIFFR 321


>gi|55926200 potassium channel tetramerisation domain containing 16
           [Homo sapiens]
          Length = 428

 Score =  315 bits (806), Expect = 5e-86
 Identities = 167/302 (55%), Positives = 207/302 (68%), Gaps = 41/302 (13%)

Query: 26  SAEPPLFPDIVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQP--QELARDSKGRFFLD 83
           SA P  FP++VELNVGGQVY TR  T++S+P SLLW+MF+ ++    +LA+DSKGRFF+D
Sbjct: 17  SAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFID 76

Query: 84  RDGFLFRYILDYLRDLQLVLPDYFPERSRLQREAEYFELPELVRRLGAPQQPGPGPPPSR 143
           RDGFLFRYILDYLRD Q+VLPD+FPE+ RL+REAEYF+LP+LV+ L  P +    P    
Sbjct: 77  RDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLL-TPDEIKQSP---- 131

Query: 144 RGVHKEGSLGDELLPLGYSEPEQQEGASAGAPSPTLELASRSPSGGAAGPLLTPSQSLDG 203
                     DE     + +  Q                      G+   +  PS  L  
Sbjct: 132 ----------DEFCHSDFEDASQ----------------------GSDTRICPPSSLLPA 159

Query: 204 SRRSGYITIGYRGSYTIGRDAQADAKFRRVARITVCGKTSLAKEVFGDTLNESRDPDRPP 263
            R+ G+IT+GYRGS T+GR+ QADAKFRRV RI VCG+ SLAKEVFG+TLNESRDPDR P
Sbjct: 160 DRKWGFITVGYRGSCTLGREGQADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDRAP 219

Query: 264 ERYTSRYYLKFNFLEQAFDKLSESGFHMVACSSTGTCAFASSTDQSEDKIWTSYTEYVFC 323
           ERYTSR+YLKF  LE+AFD LSE GFHMVAC+S+ T +F +    ++DKIW+SYTEYVF 
Sbjct: 220 ERYTSRFYLKFKHLERAFDMLSECGFHMVACNSSVTASFIN--QYTDDKIWSSYTEYVFY 277

Query: 324 RE 325
           RE
Sbjct: 278 RE 279


>gi|71143104 potassium channel tetramerisation domain containing 21
           [Homo sapiens]
          Length = 260

 Score = 88.2 bits (217), Expect = 9e-18
 Identities = 44/96 (45%), Positives = 65/96 (67%), Gaps = 2/96 (2%)

Query: 34  DIVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDSKGRFFLDRDGFLFRYIL 93
           D + LNVGG++Y T   T+ S PDS+L  MF+ + P +  RDS+G  F+DRDG +FRYIL
Sbjct: 3   DPITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTK--RDSQGNCFIDRDGKVFRYIL 60

Query: 94  DYLRDLQLVLPDYFPERSRLQREAEYFELPELVRRL 129
           ++LR   L LP+ F E   L+REA+++++  L+  L
Sbjct: 61  NFLRTSHLDLPEDFQEMGLLRREADFYQVQPLIEAL 96


>gi|189571693 potassium channel tetramerisation domain containing 6
           [Homo sapiens]
          Length = 237

 Score = 85.1 bits (209), Expect = 8e-17
 Identities = 44/103 (42%), Positives = 65/103 (63%), Gaps = 2/103 (1%)

Query: 31  LFPDIVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDSKGRFFLDRDGFLFR 90
           +  D V LNVGG +Y T   T+   PDS+L  MF    P   ARD +G +F+DRDG LFR
Sbjct: 9   MMTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPT--ARDPQGNYFIDRDGPLFR 66

Query: 91  YILDYLRDLQLVLPDYFPERSRLQREAEYFELPELVRRLGAPQ 133
           Y+L++LR  +L LP  F E   L++EA+++++  L++ L  P+
Sbjct: 67  YVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPK 109


>gi|189571691 potassium channel tetramerisation domain containing 6
           [Homo sapiens]
          Length = 237

 Score = 85.1 bits (209), Expect = 8e-17
 Identities = 44/103 (42%), Positives = 65/103 (63%), Gaps = 2/103 (1%)

Query: 31  LFPDIVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDSKGRFFLDRDGFLFR 90
           +  D V LNVGG +Y T   T+   PDS+L  MF    P   ARD +G +F+DRDG LFR
Sbjct: 9   MMTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPT--ARDPQGNYFIDRDGPLFR 66

Query: 91  YILDYLRDLQLVLPDYFPERSRLQREAEYFELPELVRRLGAPQ 133
           Y+L++LR  +L LP  F E   L++EA+++++  L++ L  P+
Sbjct: 67  YVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPK 109


>gi|194018443 potassium channel tetramerisation domain containing 15
           isoform 2 [Homo sapiens]
          Length = 283

 Score = 78.6 bits (192), Expect = 7e-15
 Identities = 42/100 (42%), Positives = 62/100 (62%), Gaps = 3/100 (3%)

Query: 36  VELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDS-KGRFFLDRDGFLFRYILD 94
           V ++VGG +Y +   T+   PDS + R+F   +P  +  DS K  +F+DRDG +FRY+L 
Sbjct: 58  VHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEP--IVLDSLKQHYFIDRDGEIFRYVLS 115

Query: 95  YLRDLQLVLPDYFPERSRLQREAEYFELPELVRRLGAPQQ 134
           +LR  +L+LPD F + S L  EA Y++L  +VR L   QQ
Sbjct: 116 FLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQ 155


>gi|194018441 potassium channel tetramerisation domain containing 15
           isoform 2 [Homo sapiens]
          Length = 283

 Score = 78.6 bits (192), Expect = 7e-15
 Identities = 42/100 (42%), Positives = 62/100 (62%), Gaps = 3/100 (3%)

Query: 36  VELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDS-KGRFFLDRDGFLFRYILD 94
           V ++VGG +Y +   T+   PDS + R+F   +P  +  DS K  +F+DRDG +FRY+L 
Sbjct: 58  VHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEP--IVLDSLKQHYFIDRDGEIFRYVLS 115

Query: 95  YLRDLQLVLPDYFPERSRLQREAEYFELPELVRRLGAPQQ 134
           +LR  +L+LPD F + S L  EA Y++L  +VR L   QQ
Sbjct: 116 FLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQ 155


>gi|194018439 potassium channel tetramerisation domain containing 15
           isoform 1 [Homo sapiens]
          Length = 234

 Score = 78.6 bits (192), Expect = 7e-15
 Identities = 42/100 (42%), Positives = 62/100 (62%), Gaps = 3/100 (3%)

Query: 36  VELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDS-KGRFFLDRDGFLFRYILD 94
           V ++VGG +Y +   T+   PDS + R+F   +P  +  DS K  +F+DRDG +FRY+L 
Sbjct: 58  VHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEP--IVLDSLKQHYFIDRDGEIFRYVLS 115

Query: 95  YLRDLQLVLPDYFPERSRLQREAEYFELPELVRRLGAPQQ 134
           +LR  +L+LPD F + S L  EA Y++L  +VR L   QQ
Sbjct: 116 FLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQ 155


>gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]
          Length = 229

 Score = 75.1 bits (183), Expect = 8e-14
 Identities = 42/93 (45%), Positives = 59/93 (63%), Gaps = 2/93 (2%)

Query: 34  DIVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDSKGRFFLDRDGFLFRYIL 93
           ++V LNVGG+++ TR  T+   P S L RM   +  +   +   G+ F+DRDG LF +IL
Sbjct: 5   ELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQE--FKMVGGQIFVDRDGDLFSFIL 62

Query: 94  DYLRDLQLVLPDYFPERSRLQREAEYFELPELV 126
           D+LR  QL+LP  F +  RLQREA ++EL  LV
Sbjct: 63  DFLRTHQLLLPTEFSDYLRLQREALFYELRSLV 95


>gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]
          Length = 272

 Score = 75.1 bits (183), Expect = 8e-14
 Identities = 42/93 (45%), Positives = 59/93 (63%), Gaps = 2/93 (2%)

Query: 34  DIVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDSKGRFFLDRDGFLFRYIL 93
           ++V LNVGG+++ TR  T+   P S L RM   +  +   +   G+ F+DRDG LF +IL
Sbjct: 5   ELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQE--FKMVGGQIFVDRDGDLFSFIL 62

Query: 94  DYLRDLQLVLPDYFPERSRLQREAEYFELPELV 126
           D+LR  QL+LP  F +  RLQREA ++EL  LV
Sbjct: 63  DFLRTHQLLLPTEFSDYLRLQREALFYELRSLV 95


>gi|146198864 potassium channel tetramerisation domain containing 4
           [Homo sapiens]
          Length = 259

 Score = 72.4 bits (176), Expect = 5e-13
 Identities = 36/95 (37%), Positives = 61/95 (64%), Gaps = 2/95 (2%)

Query: 35  IVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDSKGRFFLDRDGFLFRYILD 94
           ++ LNVGG +Y+T++ T+   PD+ L  +   +       D+ G +F+DRDG LFR++L+
Sbjct: 34  LMTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPF--DADGHYFIDRDGLLFRHVLN 91

Query: 95  YLRDLQLVLPDYFPERSRLQREAEYFELPELVRRL 129
           +LR+ +L+LP+ F E   L +EAE+F+L  L   +
Sbjct: 92  FLRNGELLLPEGFRENQLLAQEAEFFQLKGLAEEV 126


>gi|218505694 potassium channel tetramerisation domain containing 1
           isoform b [Homo sapiens]
          Length = 865

 Score = 72.0 bits (175), Expect = 7e-13
 Identities = 36/92 (39%), Positives = 60/92 (65%), Gaps = 3/92 (3%)

Query: 36  VELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDS-KGRFFLDRDGFLFRYILD 94
           V ++VGG +Y +   T+   P+S + R+F   +P  +  DS K  +F+DRDG +FRYIL+
Sbjct: 640 VHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEP--IVLDSLKQHYFIDRDGQMFRYILN 697

Query: 95  YLRDLQLVLPDYFPERSRLQREAEYFELPELV 126
           +LR  +L++PD F + + L  EA+YF+L  ++
Sbjct: 698 FLRTSKLLIPDDFKDYTLLYEEAKYFQLQPML 729


>gi|209969708 potassium channel tetramerisation domain containing 1
           isoform a [Homo sapiens]
          Length = 257

 Score = 72.0 bits (175), Expect = 7e-13
 Identities = 36/92 (39%), Positives = 60/92 (65%), Gaps = 3/92 (3%)

Query: 36  VELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDS-KGRFFLDRDGFLFRYILD 94
           V ++VGG +Y +   T+   P+S + R+F   +P  +  DS K  +F+DRDG +FRYIL+
Sbjct: 32  VHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEP--IVLDSLKQHYFIDRDGQMFRYILN 89

Query: 95  YLRDLQLVLPDYFPERSRLQREAEYFELPELV 126
           +LR  +L++PD F + + L  EA+YF+L  ++
Sbjct: 90  FLRTSKLLIPDDFKDYTLLYEEAKYFQLQPML 121


>gi|40217617 potassium channel tetramerisation domain containing 1
           isoform a [Homo sapiens]
          Length = 257

 Score = 72.0 bits (175), Expect = 7e-13
 Identities = 36/92 (39%), Positives = 60/92 (65%), Gaps = 3/92 (3%)

Query: 36  VELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDS-KGRFFLDRDGFLFRYILD 94
           V ++VGG +Y +   T+   P+S + R+F   +P  +  DS K  +F+DRDG +FRYIL+
Sbjct: 32  VHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEP--IVLDSLKQHYFIDRDGQMFRYILN 89

Query: 95  YLRDLQLVLPDYFPERSRLQREAEYFELPELV 126
           +LR  +L++PD F + + L  EA+YF+L  ++
Sbjct: 90  FLRTSKLLIPDDFKDYTLLYEEAKYFQLQPML 121


>gi|45387953 potassium channel tetramerization domain containing 18
           [Homo sapiens]
          Length = 426

 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 38/90 (42%), Positives = 54/90 (60%), Gaps = 3/90 (3%)

Query: 34  DIVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDSKGRFFLDRDGFLFRYIL 93
           D++ LNVGG +Y  RR ++    DS+L  MF+ + P  L  D  G   +DRDG LF+Y+L
Sbjct: 12  DVLRLNVGGCIYTARRESLCRFKDSMLASMFSGRFP--LKTDESGACVIDRDGRLFKYLL 69

Query: 94  DYLRDLQLVLPDYFPERSRLQREAEYFELP 123
           DYL   ++ +P     R  LQ EA+YF +P
Sbjct: 70  DYLHG-EVQIPTDEQTRIALQEEADYFGIP 98


>gi|142356950 potassium channel tetramerisation domain containing 14
           [Homo sapiens]
          Length = 255

 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 41/100 (41%), Positives = 58/100 (58%), Gaps = 6/100 (6%)

Query: 30  PLFPDIVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDSKGRFFLDRDGFLF 89
           P    +VELNVGG+ + T   T+   P S L  MF+     + + D++GRFF+DR    F
Sbjct: 29  PTMSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLA--KASTDAEGRFFIDRPSTYF 86

Query: 90  RYILDYLRDLQLVLPDYFPERSRLQREAEYFELPELVRRL 129
           R ILDYLR  Q V   + PE   + REA+++E+  LV+ L
Sbjct: 87  RPILDYLRTGQ-VPTQHIPE---VYREAQFYEIKPLVKLL 122


>gi|23308551 potassium channel tetramerisation domain containing 7
           [Homo sapiens]
          Length = 289

 Score = 62.4 bits (150), Expect = 5e-10
 Identities = 37/104 (35%), Positives = 61/104 (58%), Gaps = 11/104 (10%)

Query: 29  PPLFPDIVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDSKGRFFLDRDGFL 88
           P  FP++V LN+GG  + TR  T+    D++L  MF+ +    +  DS+GR+F+DRDG  
Sbjct: 46  PQEFPEVVPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGR--HYIPTDSEGRYFIDRDGTH 103

Query: 89  FRYILDYLRDLQLVLPDYFPERSRLQ---REAEYFELPELVRRL 129
           F  +L++LR   L      P R R++   +EA+Y+ +  L+ +L
Sbjct: 104 FGDVLNFLRSGDL------PPRERVRAVYKEAQYYAIGPLLEQL 141


>gi|53829365 potassium channel tetramerisation domain containing 2
           [Homo sapiens]
          Length = 263

 Score = 61.6 bits (148), Expect = 9e-10
 Identities = 42/120 (35%), Positives = 60/120 (50%), Gaps = 15/120 (12%)

Query: 9   GLPNGGGGGGGSGSSSSSAEPPLFPDIVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQ 68
           G P   GGGG +               V LNVGG  +VT R T+   P S L R+  Q+ 
Sbjct: 60  GPPERAGGGGAARW-------------VRLNVGGTYFVTTRQTLGREPKSFLCRLCCQED 106

Query: 69  PQ-ELARDSKGRFFLDRDGFLFRYILDYLRDLQLVLPDYFPERSRLQREAEYFELPELVR 127
           P+ +  +D  G + +DRD   F  IL+YLR  +L++     E   L+ EAE++ +  LVR
Sbjct: 107 PELDSDKDETGAYLIDRDPTYFGPILNYLRHGKLIITKELAEEGVLE-EAEFYNIASLVR 165


>gi|9506651 potassium channel tetramerisation domain containing 5
           [Homo sapiens]
          Length = 234

 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 40/130 (30%), Positives = 62/130 (47%), Gaps = 6/130 (4%)

Query: 3   LADSTRGLPNGGGGGG-----GSGSSSSSAEPPLFPDIVELNVGGQVYVTRRCTVVSVPD 57
           L    RG    G GGG      +G  + +  P      V LNVGG  ++T R T+   P 
Sbjct: 8   LLSPARGGIGAGLGGGLCRRCSAGLGALAQRPGSVSKWVRLNVGGTYFLTTRQTLCRDPK 67

Query: 58  SLLWRMFTQQQPQELARDSKGRFFLDRDGFLFRYILDYLRDLQLVLPDYFPERSRLQREA 117
           S L+R+       +  +D  G + +DRD   F  +L+YLR  +LV+     E   L+ EA
Sbjct: 68  SFLYRLCQADPDLDSDKDETGAYLIDRDPTYFGPVLNYLRHGKLVINKDLAEEGVLE-EA 126

Query: 118 EYFELPELVR 127
           E++ +  L++
Sbjct: 127 EFYNITSLIK 136


>gi|46255026 potassium channel tetramerisation domain containing 3
           [Homo sapiens]
          Length = 815

 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 41/113 (36%), Positives = 61/113 (53%), Gaps = 6/113 (5%)

Query: 17  GGGSGSSSSSAEPPLFPDIVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDS 76
           GG  GS  ++A      +IV+LNVGG  + T R T++ +PDS    + + +      RD 
Sbjct: 3   GGHCGSFPAAAAGS--GEIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGR--ISTLRDE 58

Query: 77  KGRFFLDRDGFLFRYILDYLRDLQLVLPDYFPERSRLQREAEYFELPELVRRL 129
            G  F+DRD   F  IL++LR  +L L       + L+ EAE++ +  LVRRL
Sbjct: 59  TGAIFIDRDPAAFAPILNFLRTKELDLRGV--SINVLRHEAEFYGITPLVRRL 109


>gi|39753959 potassium channel tetramerisation domain containing 9
           [Homo sapiens]
          Length = 389

 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 41/116 (35%), Positives = 59/116 (50%), Gaps = 6/116 (5%)

Query: 34  DIVELNVGGQVYVTRRCTVVSV-PDSLLWRMFTQQQPQELARDSKGRFFLDRDGFLFRYI 92
           D + LNVGG+ + T R T+V+  PDS+L  MF  +      +D +G F +DR    F  I
Sbjct: 89  DWLTLNVGGRYFTTTRSTLVNKEPDSMLAHMFKDKGVWGNKQDHRGAFLIDRSPEYFEPI 148

Query: 93  LDYLRDLQLVLPDYFPERSRLQREAEYFELPELVRRLGA----PQQPGPGPPPSRR 144
           L+YLR  QL++ D       L+ EA +F +  L+  L       Q P    P SR+
Sbjct: 149 LNYLRHGQLIVNDGINLLGVLE-EARFFGIDSLIEHLEVAIKNSQPPEDHSPISRK 203


>gi|169234778 potassium channel tetramerisation domain containing 17
           [Homo sapiens]
          Length = 297

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 40/117 (34%), Positives = 58/117 (49%), Gaps = 11/117 (9%)

Query: 11  PNGGGGGGGSGSSSSSAEPPLFPDIVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQ 70
           P  G GG  +G          +   V LNVGG V++T R T+     S L R+   ++ Q
Sbjct: 17  PPAGAGGRAAGG---------WGKWVRLNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQ 67

Query: 71  ELARDSKGRFFLDRDGFLFRYILDYLRDLQLVLPDYFPERSRLQREAEYFELPELVR 127
              RD  G + +DRD   F  IL++LR  +LVL     E   L+ EAE++ +  L+R
Sbjct: 68  S-DRDETGAYLIDRDPTYFGPILNFLRHGKLVLDKDMAEEGVLE-EAEFYNIGPLIR 122


>gi|13994353 potassium channel tetramerisation domain containing 10
           [Homo sapiens]
          Length = 313

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 38/99 (38%), Positives = 54/99 (54%), Gaps = 3/99 (3%)

Query: 36  VELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDSKGRFFLDRDGFLFRYILDY 95
           V+LNVGG +Y T   T+    D++L  MF+ +   E+  DS+G   +DR G  F  IL+Y
Sbjct: 34  VKLNVGGALYYTTMQTLTK-QDTMLKAMFSGRM--EVLTDSEGWILIDRCGKHFGTILNY 90

Query: 96  LRDLQLVLPDYFPERSRLQREAEYFELPELVRRLGAPQQ 134
           LRD  + LP+   E   L  EA+Y+ +  LV    A  Q
Sbjct: 91  LRDGAVPLPESRREIEELLAEAKYYLVQGLVEECQAALQ 129


>gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]
          Length = 707

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 58/211 (27%), Positives = 84/211 (39%), Gaps = 39/211 (18%)

Query: 2   ALADSTRGLPNGGGGGGGSGSSSSSAEPPLFPDIVELNVGGQVYVTRRCTVVSVPDSLLW 61
           A A +  G+P+ G  G                +++ LNVGG+ + T R T+  +PDS   
Sbjct: 3   AAATAAEGVPSRGPPG----------------EVIHLNVGGKRFSTSRQTLTWIPDSFFS 46

Query: 62  RMFTQQQPQELARDSKGRFFLDRDGFLFRYILDYLRDLQLVLPDYFPERSRLQREAEYFE 121
            + + +      +D  G  F+DRD  +F  IL++LR  +  L       S L  EA+++ 
Sbjct: 47  SLLSGR--ISTLKDETGAIFIDRDPTVFAPILNFLRTKE--LDPRGVHGSSLLHEAQFYG 102

Query: 122 LPELVRRLGAPQQ---------------PGPGPPPSRRGVHK---EGSLGDELLPLGYSE 163
           L  LVRRL   ++               P P  P  RR  H       LG    P+  S 
Sbjct: 103 LTPLVRRLQLREELDRSSCGNVLFNGYLPPPVFPVKRRNRHSLVGPQQLGGRPAPVRRSN 162

Query: 164 PEQQEGASAGAPSPTL-ELASRSPSGGAAGP 193
                  +AG     L E    SPSG    P
Sbjct: 163 TMPPNLGNAGLLGRMLDEKTPPSPSGQPEEP 193


>gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo
           sapiens]
          Length = 316

 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 39/113 (34%), Positives = 56/113 (49%), Gaps = 14/113 (12%)

Query: 14  GGGGGGSGSSSSSAEPPLFPDIVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELA 73
           G  GGG G+             V+LNVGG +Y T     ++  D++L  MF+ +   E+ 
Sbjct: 19  GFKGGGLGNK-----------YVQLNVGGSLYYTT-VRALTRHDTMLKAMFSGRM--EVL 64

Query: 74  RDSKGRFFLDRDGFLFRYILDYLRDLQLVLPDYFPERSRLQREAEYFELPELV 126
            D +G   +DR G  F  IL+YLRD  + LP    E   L  EA+Y+ +  LV
Sbjct: 65  TDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGLV 117


>gi|30578412 potassium channel tetramerisation domain containing 13
           [Homo sapiens]
          Length = 329

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 36/99 (36%), Positives = 54/99 (54%), Gaps = 5/99 (5%)

Query: 30  PLFPD--IVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDSKGRFFLDRDGF 87
           PL P+   V+LNVGG ++ T   T+    D++L  MF+ +   E+  D+ G   +DR G 
Sbjct: 35  PLTPNSKYVKLNVGGSLHYTTLRTLTG-QDTMLKAMFSGRV--EVLTDAGGWVLIDRSGR 91

Query: 88  LFRYILDYLRDLQLVLPDYFPERSRLQREAEYFELPELV 126
            F  IL+YLRD  + LP+   E   L  EA Y+ +  L+
Sbjct: 92  HFGTILNYLRDGSVPLPESTRELGELLGEARYYLVQGLI 130


>gi|51036594 potassium channel tetramerisation domain containing 11
           [Homo sapiens]
          Length = 232

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 27/89 (30%), Positives = 48/89 (53%)

Query: 69  PQELARDSKGRFFLDRDGFLFRYILDYLRDLQLVLPDYFPERSRLQREAEYFELPELVRR 128
           P  L     G +F+DRDG  FR+IL++LR  +L LP  + E + L+ EA+++++  L+  
Sbjct: 13  PPNLNSQGGGHYFIDRDGKAFRHILNFLRLGRLDLPRGYGETALLRAEADFYQIRPLLDA 72

Query: 129 LGAPQQPGPGPPPSRRGVHKEGSLGDELL 157
           L   +     P P+   +H +  +   L+
Sbjct: 73  LRELEASQGTPAPTAALLHADVDVSPRLV 101


>gi|169184031 PREDICTED: similar to potassium channel
           tetramerisation domain containing 9 [Homo sapiens]
          Length = 261

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 33/97 (34%), Positives = 51/97 (52%), Gaps = 2/97 (2%)

Query: 34  DIVELNVGGQVYVTRRCTVVSV-PDSLLWRMFTQQQPQELARDSKGRFFLDRDGFLFRYI 92
           D + L+VGGQ + T   T+V+  PD +L  MF  +      +D +G F +D+    F  I
Sbjct: 89  DWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQDHRGAFLIDQSPEYFEPI 148

Query: 93  LDYLRDLQLVLPDYFPERSRLQREAEYFELPELVRRL 129
           L+YLR  QL++ D       L+ EA +F +  L+  L
Sbjct: 149 LNYLRHGQLIVNDGIDLLGVLE-EARFFGIDSLIEHL 184


>gi|169179790 PREDICTED: similar to potassium channel
           tetramerisation domain containing 9 [Homo sapiens]
          Length = 261

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 33/97 (34%), Positives = 51/97 (52%), Gaps = 2/97 (2%)

Query: 34  DIVELNVGGQVYVTRRCTVVSV-PDSLLWRMFTQQQPQELARDSKGRFFLDRDGFLFRYI 92
           D + L+VGGQ + T   T+V+  PD +L  MF  +      +D +G F +D+    F  I
Sbjct: 89  DWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQDHRGAFLIDQSPEYFEPI 148

Query: 93  LDYLRDLQLVLPDYFPERSRLQREAEYFELPELVRRL 129
           L+YLR  QL++ D       L+ EA +F +  L+  L
Sbjct: 149 LNYLRHGQLIVNDGIDLLGVLE-EARFFGIDSLIEHL 184


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.136    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,015,214
Number of Sequences: 37866
Number of extensions: 847052
Number of successful extensions: 9697
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 115
Number of HSP's successfully gapped in prelim test: 205
Number of HSP's that attempted gapping in prelim test: 8576
Number of HSP's gapped (non-prelim): 1140
length of query: 325
length of database: 18,247,518
effective HSP length: 102
effective length of query: 223
effective length of database: 14,385,186
effective search space: 3207896478
effective search space used: 3207896478
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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