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Search of human proteins with 19923615
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19923615 myosin head domain containing 1 isoform 1 [Homo
sapiens]
(770 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19923615 myosin head domain containing 1 isoform 1 [Homo sapi... 1566 0.0
gi|75812980 myosin head domain containing 1 isoform 3 [Homo sapi... 610 e-174
gi|92859701 myosin VI [Homo sapiens] 266 7e-71
gi|215982794 myosin VA isoform 2 [Homo sapiens] 258 1e-68
gi|215982791 myosin VA isoform 1 [Homo sapiens] 258 1e-68
gi|153945715 myosin VC [Homo sapiens] 253 4e-67
gi|122937345 myosin VB [Homo sapiens] 249 7e-66
gi|194272142 myosin IXB isoform 2 [Homo sapiens] 248 2e-65
gi|33356170 myosin IXB isoform 1 [Homo sapiens] 248 2e-65
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 247 3e-65
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 247 3e-65
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 246 6e-65
gi|239582755 myosin IG [Homo sapiens] 245 1e-64
gi|189083802 myosin VIIA isoform 2 [Homo sapiens] 245 1e-64
gi|189083800 myosin VIIA isoform 3 [Homo sapiens] 245 1e-64
gi|189083798 myosin VIIA isoform 1 [Homo sapiens] 245 1e-64
gi|156119615 myosin IXA [Homo sapiens] 243 4e-64
gi|194328685 myosin IB isoform 1 [Homo sapiens] 242 8e-64
gi|44889481 myosin IB isoform 2 [Homo sapiens] 242 8e-64
gi|240120050 myosin IB isoform 1 [Homo sapiens] 242 8e-64
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 241 1e-63
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 241 1e-63
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 241 1e-63
gi|55956916 myosin IE [Homo sapiens] 239 9e-63
gi|27544941 myosin IF [Homo sapiens] 238 1e-62
gi|124494238 myosin IC isoform a [Homo sapiens] 238 2e-62
gi|124494247 myosin IC isoform b [Homo sapiens] 237 3e-62
gi|124494240 myosin IC isoform c [Homo sapiens] 237 3e-62
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 235 1e-61
gi|118402590 myosin XV [Homo sapiens] 231 1e-60
>gi|19923615 myosin head domain containing 1 isoform 1 [Homo
sapiens]
Length = 770
Score = 1566 bits (4055), Expect = 0.0
Identities = 770/770 (100%), Positives = 770/770 (100%)
Query: 1 MLQQVNGHNPGSDGQAREYLREDLQEFLGGEVLLYKLDDLTRVNPVTLETVLRCLQARYM 60
MLQQVNGHNPGSDGQAREYLREDLQEFLGGEVLLYKLDDLTRVNPVTLETVLRCLQARYM
Sbjct: 1 MLQQVNGHNPGSDGQAREYLREDLQEFLGGEVLLYKLDDLTRVNPVTLETVLRCLQARYM 60
Query: 61 ADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHAAPQPQKLKPHVFTVGEQTYRNVKSL 120
ADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHAAPQPQKLKPHVFTVGEQTYRNVKSL
Sbjct: 61 ADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHAAPQPQKLKPHVFTVGEQTYRNVKSL 120
Query: 121 IEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATSPASWESHKIAERIEQRILNSNPVME 180
IEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATSPASWESHKIAERIEQRILNSNPVME
Sbjct: 121 IEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATSPASWESHKIAERIEQRILNSNPVME 180
Query: 181 AFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQTYLLEKTRVACQASSERNFHIFYQ 240
AFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQTYLLEKTRVACQASSERNFHIFYQ
Sbjct: 181 AFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQTYLLEKTRVACQASSERNFHIFYQ 240
Query: 241 ICKGASEDERLQWHLPEGAAFSWLPNPERSLEEDCFEVTREAMLHLGIDTPTQNNIFKVL 300
ICKGASEDERLQWHLPEGAAFSWLPNPERSLEEDCFEVTREAMLHLGIDTPTQNNIFKVL
Sbjct: 241 ICKGASEDERLQWHLPEGAAFSWLPNPERSLEEDCFEVTREAMLHLGIDTPTQNNIFKVL 300
Query: 301 AGLLHLGNIQFAASEDEAQPCQPMDDAKYSVRTAASLLGLPEDVLLEMVQIRTIRAGRQQ 360
AGLLHLGNIQFAASEDEAQPCQPMDDAKYSVRTAASLLGLPEDVLLEMVQIRTIRAGRQQ
Sbjct: 301 AGLLHLGNIQFAASEDEAQPCQPMDDAKYSVRTAASLLGLPEDVLLEMVQIRTIRAGRQQ 360
Query: 361 QVFRKPCARAECDTRRDCLAKLIYARLFDWLVSVINSSICADTDSWTTFIGLLDVYGFES 420
QVFRKPCARAECDTRRDCLAKLIYARLFDWLVSVINSSICADTDSWTTFIGLLDVYGFES
Sbjct: 361 QVFRKPCARAECDTRRDCLAKLIYARLFDWLVSVINSSICADTDSWTTFIGLLDVYGFES 420
Query: 421 FPDNSLEQLCINYANEKLQLEACGLVETIHISAAGFPIRVSHRNFVERYKLLRRLHPCTS 480
FPDNSLEQLCINYANEKLQLEACGLVETIHISAAGFPIRVSHRNFVERYKLLRRLHPCTS
Sbjct: 421 FPDNSLEQLCINYANEKLQLEACGLVETIHISAAGFPIRVSHRNFVERYKLLRRLHPCTS 480
Query: 481 SGPDSPYPAKGLPEWCPHSEEATLEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHCGR 540
SGPDSPYPAKGLPEWCPHSEEATLEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHCGR
Sbjct: 481 SGPDSPYPAKGLPEWCPHSEEATLEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHCGR 540
Query: 541 TKVFMTDSMLELLECGRARVLEQCARCIQGGWRRHRHREQERQWRAVMLIQAAIRSWLTR 600
TKVFMTDSMLELLECGRARVLEQCARCIQGGWRRHRHREQERQWRAVMLIQAAIRSWLTR
Sbjct: 541 TKVFMTDSMLELLECGRARVLEQCARCIQGGWRRHRHREQERQWRAVMLIQAAIRSWLTR 600
Query: 601 KHIQRLHAAATVIKRAWQKWRIRMACLAAKELDGVEEKHFSQAPCSLSTSPLQTRLLEAI 660
KHIQRLHAAATVIKRAWQKWRIRMACLAAKELDGVEEKHFSQAPCSLSTSPLQTRLLEAI
Sbjct: 601 KHIQRLHAAATVIKRAWQKWRIRMACLAAKELDGVEEKHFSQAPCSLSTSPLQTRLLEAI 660
Query: 661 IRLWPLGLVLANTAMGVGSFQRKLVVWACLQLPRGSPSSYTVQTAQDQAGVTSIRALPQG 720
IRLWPLGLVLANTAMGVGSFQRKLVVWACLQLPRGSPSSYTVQTAQDQAGVTSIRALPQG
Sbjct: 661 IRLWPLGLVLANTAMGVGSFQRKLVVWACLQLPRGSPSSYTVQTAQDQAGVTSIRALPQG 720
Query: 721 SIKFHCRKSPLRYADICPEPSPYSITGFNQILLERHRLIHVTSSAFTGLG 770
SIKFHCRKSPLRYADICPEPSPYSITGFNQILLERHRLIHVTSSAFTGLG
Sbjct: 721 SIKFHCRKSPLRYADICPEPSPYSITGFNQILLERHRLIHVTSSAFTGLG 770
>gi|75812980 myosin head domain containing 1 isoform 3 [Homo
sapiens]
Length = 317
Score = 610 bits (1574), Expect = e-174
Identities = 299/299 (100%), Positives = 299/299 (100%)
Query: 1 MLQQVNGHNPGSDGQAREYLREDLQEFLGGEVLLYKLDDLTRVNPVTLETVLRCLQARYM 60
MLQQVNGHNPGSDGQAREYLREDLQEFLGGEVLLYKLDDLTRVNPVTLETVLRCLQARYM
Sbjct: 1 MLQQVNGHNPGSDGQAREYLREDLQEFLGGEVLLYKLDDLTRVNPVTLETVLRCLQARYM 60
Query: 61 ADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHAAPQPQKLKPHVFTVGEQTYRNVKSL 120
ADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHAAPQPQKLKPHVFTVGEQTYRNVKSL
Sbjct: 61 ADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHAAPQPQKLKPHVFTVGEQTYRNVKSL 120
Query: 121 IEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATSPASWESHKIAERIEQRILNSNPVME 180
IEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATSPASWESHKIAERIEQRILNSNPVME
Sbjct: 121 IEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATSPASWESHKIAERIEQRILNSNPVME 180
Query: 181 AFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQTYLLEKTRVACQASSERNFHIFYQ 240
AFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQTYLLEKTRVACQASSERNFHIFYQ
Sbjct: 181 AFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQTYLLEKTRVACQASSERNFHIFYQ 240
Query: 241 ICKGASEDERLQWHLPEGAAFSWLPNPERSLEEDCFEVTREAMLHLGIDTPTQNNIFKV 299
ICKGASEDERLQWHLPEGAAFSWLPNPERSLEEDCFEVTREAMLHLGIDTPTQNNIFKV
Sbjct: 241 ICKGASEDERLQWHLPEGAAFSWLPNPERSLEEDCFEVTREAMLHLGIDTPTQNNIFKV 299
>gi|92859701 myosin VI [Homo sapiens]
Length = 1285
Score = 266 bits (679), Expect = 7e-71
Identities = 158/424 (37%), Positives = 235/424 (55%), Gaps = 48/424 (11%)
Query: 50 TVLRCLQARYMADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHAAPQPQKLKPHVFTV 109
T+L ++ RY D YT L+A+NP+ +P++YS E ++ Y + PHVF +
Sbjct: 72 TLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSEAIKSYQGKSLGTR-PPHVFAI 130
Query: 110 GEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATSPASWESHKIAERIE 169
++ +R++K L ++QSI+VSGESGAGKT ++ ++++ ES+ + I+
Sbjct: 131 ADKAFRDMKVL--KMSQSIIVSGESGAGKTENTKFVLRYLT---------ESYGTGQDID 179
Query: 170 QRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQTYLLEKTRVACQA 229
RI+ +NP++EAFGNA T+RNNNSSRFGKF+++ N + G V YLLEK+R+ Q
Sbjct: 180 DRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRICVQG 239
Query: 230 SSERNFHIFYQICKGASEDERLQWHLPEGAAFSWL---------------------PNPE 268
ERN+HIFY++C GASED R + HL F +L +PE
Sbjct: 240 KEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDKQILQNRKSPE 299
Query: 269 --------RSLEEDCFEVTR--EAMLHLGIDTPTQNNIFKVLAGLLHLGNIQFAASEDEA 318
L +D + R AM +G+D + ++F+V+AG+LHLGNI F + +
Sbjct: 300 YLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEEAGSTS 359
Query: 319 QPCQPMDDAKYSVRTAASLLGLPEDVLLEMVQIR---TIRAGRQQQVFRKPCARAECDTR 375
C + + S+ A LLGL +D L + R T G + V + P + +
Sbjct: 360 GGCNLKNKSAQSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIKVPLKVEQANNA 419
Query: 376 RDCLAKLIYARLFDWLVSVINSSICADTDSWTTFIGLLDVYGFESFPDNSLEQLCINYAN 435
RD LAK +Y+ LFD +V+ +N +T S+ FIG+LD+ GFE F NS EQ CINY N
Sbjct: 420 RDALAKTVYSHLFDHVVNRVNQCFPFETSSY--FIGVLDIAGFEYFEHNSFEQFCINYCN 477
Query: 436 EKLQ 439
EKLQ
Sbjct: 478 EKLQ 481
>gi|215982794 myosin VA isoform 2 [Homo sapiens]
Length = 1828
Score = 258 bits (660), Expect = 1e-68
Identities = 152/408 (37%), Positives = 241/408 (59%), Gaps = 23/408 (5%)
Query: 38 DDLTRVNPVTLETVLRCLQARYM-ADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHAA 96
+DLT ++ + VL L+ R++ + YT G LVA+NP++ +P +Y +++ Y +
Sbjct: 72 NDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLP-IYGEDIINAY-SG 129
Query: 97 PQPQKLKPHVFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATSP 156
+ PH+F V E+ Y+ + + NQSI+VSGESGAGKT +++ M+++A V+ S
Sbjct: 130 QNMGDMDPHIFAVAEEAYKQMAR--DERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSA 187
Query: 157 ASWESHKIAERIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQ 216
+ +E+++L SNP+ME+ GNA T RN+NSSRFGK+I++ ++ ++ GA ++
Sbjct: 188 SE-------ANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMR 240
Query: 217 TYLLEKTRVACQASSERNFHIFYQICKGASEDERLQWHLPEGAAFSWLP---NPERSLEE 273
TYLLEK+RV QA ERN+HIFYQ+C A E L F++ +P +
Sbjct: 241 TYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVD 300
Query: 274 DCFEV--TREAMLHLGIDTPTQNNIFKVLAGLLHLGNIQFAASEDEAQPCQPMDDAKYSV 331
D E+ TR+A LGI Q IF++LAG+LHLGN+ F + + ++ P + +
Sbjct: 301 DAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHE---PL 357
Query: 332 RTAASLLGLPEDVLLEMVQIRTIRAGRQQQVFRKPCARAECDTRRDCLAKLIYARLFDWL 391
L+G+ + + + R + + + KP ++ + RD LAK IYA+LF+W+
Sbjct: 358 CIFCDLMGVDYEEMCHWLCHRKLATATETYI--KPISKLQATNARDALAKHIYAKLFNWI 415
Query: 392 VSVINSSICADTDSWTTFIGLLDVYGFESFPDNSLEQLCINYANEKLQ 439
V +N ++ + +FIG+LD+YGFE+F NS EQ CINYANEKLQ
Sbjct: 416 VDNVNQALHSAVKQ-HSFIGVLDIYGFETFEINSFEQFCINYANEKLQ 462
Score = 53.1 bits (126), Expect = 9e-07
Identities = 54/192 (28%), Positives = 82/192 (42%), Gaps = 47/192 (24%)
Query: 439 QLEACGLVETIHISAAGFPIRVSHRNFVERYKLLRRLHPCTSSGPDSPYPAKGLPEWCPH 498
QL ACG++ETI ISAAGFP R +++ F RY++L + S D K +
Sbjct: 680 QLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLS---DRKQTCKNV------ 730
Query: 499 SEEATLEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHCGRTKVFMTDSMLELLECGRA 558
LE LI D G+TK+F + LE RA
Sbjct: 731 -----LEKLILD----------------------KDKYQFGKTKIFFRAGQVAYLEKLRA 763
Query: 559 RVLEQCARCIQ-----GGWRRHRHREQERQWRAVMLIQAAIRSWLTRKHIQ--RLHAAAT 611
L A CI+ GW ++ R +A + +Q +R + R + + R AAT
Sbjct: 764 DKLR--AACIRIQKTIRGWL--LRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAAT 819
Query: 612 VIKRAWQKWRIR 623
+I++ W+ + +R
Sbjct: 820 IIQKYWRMYVVR 831
Score = 32.7 bits (73), Expect = 1.3
Identities = 21/76 (27%), Positives = 42/76 (55%), Gaps = 5/76 (6%)
Query: 568 IQGGWRRHRHREQERQWRAVMLIQAAIRSWLTRKHIQR-LHAAATV---IKRAWQKWRIR 623
++G R+R+R+ R+ +AV +IQ +R WL R H +R +HA + +R K ++
Sbjct: 848 LRGFLARNRYRKILREHKAV-IIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELK 906
Query: 624 MACLAAKELDGVEEKH 639
+ A+ ++ ++ H
Sbjct: 907 KLKIEARSVERYKKLH 922
>gi|215982791 myosin VA isoform 1 [Homo sapiens]
Length = 1855
Score = 258 bits (660), Expect = 1e-68
Identities = 152/408 (37%), Positives = 241/408 (59%), Gaps = 23/408 (5%)
Query: 38 DDLTRVNPVTLETVLRCLQARYM-ADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHAA 96
+DLT ++ + VL L+ R++ + YT G LVA+NP++ +P +Y +++ Y +
Sbjct: 72 NDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLP-IYGEDIINAY-SG 129
Query: 97 PQPQKLKPHVFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATSP 156
+ PH+F V E+ Y+ + + NQSI+VSGESGAGKT +++ M+++A V+ S
Sbjct: 130 QNMGDMDPHIFAVAEEAYKQMAR--DERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSA 187
Query: 157 ASWESHKIAERIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQ 216
+ +E+++L SNP+ME+ GNA T RN+NSSRFGK+I++ ++ ++ GA ++
Sbjct: 188 SE-------ANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMR 240
Query: 217 TYLLEKTRVACQASSERNFHIFYQICKGASEDERLQWHLPEGAAFSWLP---NPERSLEE 273
TYLLEK+RV QA ERN+HIFYQ+C A E L F++ +P +
Sbjct: 241 TYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVD 300
Query: 274 DCFEV--TREAMLHLGIDTPTQNNIFKVLAGLLHLGNIQFAASEDEAQPCQPMDDAKYSV 331
D E+ TR+A LGI Q IF++LAG+LHLGN+ F + + ++ P + +
Sbjct: 301 DAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHE---PL 357
Query: 332 RTAASLLGLPEDVLLEMVQIRTIRAGRQQQVFRKPCARAECDTRRDCLAKLIYARLFDWL 391
L+G+ + + + R + + + KP ++ + RD LAK IYA+LF+W+
Sbjct: 358 CIFCDLMGVDYEEMCHWLCHRKLATATETYI--KPISKLQATNARDALAKHIYAKLFNWI 415
Query: 392 VSVINSSICADTDSWTTFIGLLDVYGFESFPDNSLEQLCINYANEKLQ 439
V +N ++ + +FIG+LD+YGFE+F NS EQ CINYANEKLQ
Sbjct: 416 VDNVNQALHSAVKQ-HSFIGVLDIYGFETFEINSFEQFCINYANEKLQ 462
Score = 53.1 bits (126), Expect = 9e-07
Identities = 54/192 (28%), Positives = 82/192 (42%), Gaps = 47/192 (24%)
Query: 439 QLEACGLVETIHISAAGFPIRVSHRNFVERYKLLRRLHPCTSSGPDSPYPAKGLPEWCPH 498
QL ACG++ETI ISAAGFP R +++ F RY++L + S D K +
Sbjct: 680 QLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLS---DRKQTCKNV------ 730
Query: 499 SEEATLEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHCGRTKVFMTDSMLELLECGRA 558
LE LI D G+TK+F + LE RA
Sbjct: 731 -----LEKLILD----------------------KDKYQFGKTKIFFRAGQVAYLEKLRA 763
Query: 559 RVLEQCARCIQ-----GGWRRHRHREQERQWRAVMLIQAAIRSWLTRKHIQ--RLHAAAT 611
L A CI+ GW ++ R +A + +Q +R + R + + R AAT
Sbjct: 764 DKLR--AACIRIQKTIRGWL--LRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAAT 819
Query: 612 VIKRAWQKWRIR 623
+I++ W+ + +R
Sbjct: 820 IIQKYWRMYVVR 831
Score = 32.7 bits (73), Expect = 1.3
Identities = 21/76 (27%), Positives = 42/76 (55%), Gaps = 5/76 (6%)
Query: 568 IQGGWRRHRHREQERQWRAVMLIQAAIRSWLTRKHIQR-LHAAATV---IKRAWQKWRIR 623
++G R+R+R+ R+ +AV +IQ +R WL R H +R +HA + +R K ++
Sbjct: 848 LRGFLARNRYRKILREHKAV-IIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELK 906
Query: 624 MACLAAKELDGVEEKH 639
+ A+ ++ ++ H
Sbjct: 907 KLKIEARSVERYKKLH 922
>gi|153945715 myosin VC [Homo sapiens]
Length = 1742
Score = 253 bits (647), Expect = 4e-67
Identities = 158/408 (38%), Positives = 232/408 (56%), Gaps = 23/408 (5%)
Query: 38 DDLTRVNPVTLETVLRCLQARYM-ADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHAA 96
+DLT ++ + VL L+ R+ + YT +G LVA+NP+K +P +Y ++ Y +
Sbjct: 70 NDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLP-IYGDAIIHAY-SG 127
Query: 97 PQPQKLKPHVFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATSP 156
+ PH+F V E+ Y+ + NQSI+VSGESGAGKT ++R M+++A V+ S
Sbjct: 128 QNMGDMDPHIFAVAEEAYKQMAR--NNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSG 185
Query: 157 ASWESHKIAERIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQ 216
++ +E ++L SNP+ EA GNA T RN+NSSRFGK+ ++ + Q+ GA +
Sbjct: 186 SN-------AHVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMS 238
Query: 217 TYLLEKTRVACQASSERNFHIFYQICKGASEDERLQWHLPEGAAFSWLPNPERSLEE--- 273
TYLLEK+RV Q+ +ERN+HIFYQ+C A + E L F++ ++ E
Sbjct: 239 TYLLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTVIEGVN 298
Query: 274 DCFEV--TREAMLHLGIDTPTQNNIFKVLAGLLHLGNIQFAASEDEAQPCQPMDDAKYSV 331
D E+ T++ LG Q ++FK+LA +LHLGN+Q A +E D +
Sbjct: 299 DRAEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDS---HL 355
Query: 332 RTAASLLGLPEDVLLEMVQIRTIRAGRQQQVFRKPCARAECDTRRDCLAKLIYARLFDWL 391
+ LLGL + + + R I + V KP R + RD LAK IYA LFD++
Sbjct: 356 KVFCELLGLESGRVAQWLCNRKIVTSSETVV--KPMTRPQAVNARDALAKKIYAHLFDFI 413
Query: 392 VSVINSSICADTDSWTTFIGLLDVYGFESFPDNSLEQLCINYANEKLQ 439
V IN ++ + TFIG+LD+YGFE+F NS EQ CINYANEKLQ
Sbjct: 414 VERINQAL-QFSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQ 460
Score = 45.8 bits (107), Expect = 1e-04
Identities = 59/212 (27%), Positives = 79/212 (37%), Gaps = 57/212 (26%)
Query: 430 CINYANEKL-----------QLEACGLVETIHISAAGFPIRVSHRNFVERYKLLRRLHPC 478
CI +EKL QL ACG++ETI ISA +P R ++ F RY +L
Sbjct: 649 CIKPNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQEL 708
Query: 479 TSSGPDSPYPAKGLPEWCPHSEEATLEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHC 538
+ S E C + L LIQD
Sbjct: 709 SFSDK---------KEVC----KVVLHRLIQD----------------------SNQYQF 733
Query: 539 GRTKVFMTDSMLELLECGRARVLEQCARCIQ---GGWRRHRHREQERQWRAVMLIQAAIR 595
G+TK+F + LE R L Q +Q GW + + +ER RA ++IQ R
Sbjct: 734 GKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLRER--RAALIIQQYFR 791
Query: 596 SWLT-RKHIQRLHAAATVIKRAWQKWRIRMAC 626
T RK I A +K AW I+ C
Sbjct: 792 GQQTVRKAI-----TAVALKEAWAAIIIQKHC 818
>gi|122937345 myosin VB [Homo sapiens]
Length = 1848
Score = 249 bits (636), Expect = 7e-66
Identities = 157/420 (37%), Positives = 239/420 (56%), Gaps = 24/420 (5%)
Query: 27 FLGGEVLLYKLDDLTRVNPVTLETVLRCLQARYM-ADTFYTNAGCTLVALNPFKPVPQLY 85
FL +L +DLT ++ + VL L+ R++ ++ YT G LVA+NP++ +P +Y
Sbjct: 61 FLRNPDILVGENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLP-IY 119
Query: 86 SPELMREYHAAPQPQKLKPHVFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCL 145
+++ Y + + PH+F V E+ Y+ + + NQSI+VSGESGAGKT +++
Sbjct: 120 GQDVIYTY-SGQNMGDMDPHIFAVAEEAYKQMAR--DEKNQSIIVSGESGAGKTVSAKYA 176
Query: 146 MKFYAVVATSPASWESHKIAERIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLN 205
M+++A V S + IE+++L S+P+MEA GNA T RN+NSSRFGK+IQ+ +
Sbjct: 177 MRYFATVGGSASE-------TNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFD 229
Query: 206 RAQQMTGAAVQTYLLEKTRVACQASSERNFHIFYQICKGASEDERLQWHLPEGAAFSWL- 264
+ + GA ++TYLLEK+RV QA ERN+HIFYQ+C A E + L F +
Sbjct: 230 KRYHIIGANMRTYLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTS 289
Query: 265 PNPERSLE----EDCFEVTREAMLHLGIDTPTQNNIFKVLAGLLHLGNIQFAASED-EAQ 319
+ S+E + FE TR+A LG+ Q +IFK++A +LHLG++ A D ++
Sbjct: 290 QGGDTSIEGVDDAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSC 349
Query: 320 PCQPMDDAKYSVRTAASLLGLPEDVLLEMVQIRTIRAGRQQQVFRKPCARAECDTRRDCL 379
P D + LLG+ + + R + + + K + + R+ L
Sbjct: 350 SISPQD---VYLSNFCRLLGVEHSQMEHWLCHRKLVT--TSETYVKTMSLQQVINARNAL 404
Query: 380 AKLIYARLFDWLVSVINSSICADTDSWTTFIGLLDVYGFESFPDNSLEQLCINYANEKLQ 439
AK IYA+LF W+V IN ++ +FIG+LD+YGFE+F NS EQ CINYANEKLQ
Sbjct: 405 AKHIYAQLFGWIVEHINKALHTSLKQ-HSFIGVLDIYGFETFEVNSFEQFCINYANEKLQ 463
Score = 52.0 bits (123), Expect = 2e-06
Identities = 57/213 (26%), Positives = 87/213 (40%), Gaps = 55/213 (25%)
Query: 430 CINYANEKL-----------QLEACGLVETIHISAAGFPIRVSHRNFVERYKLLRRLHPC 478
CI +EKL QL ACG++ETI ISAAG+P R ++ +F RY++L +
Sbjct: 657 CIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKKREL 716
Query: 479 TSSGPDSPYPAKGLPEWCPHSEEATLEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHC 538
++ + + LE LI+D P
Sbjct: 717 ANTDKKAIC-------------RSVLENLIKD----------------------PDKFQF 741
Query: 539 GRTKVFMTDSMLELLECGRARVLEQCARCIQ---GGWRRHRHREQERQWRAVMLIQAAIR 595
GRTK+F + LE RA IQ GW + + R A + +Q R
Sbjct: 742 GRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRGWL--QKVKYHRLKGATLTLQRYCR 799
Query: 596 SWLTRK---HIQRLHAAATVIKRAWQKWRIRMA 625
L R+ H++R+ AA V+++ ++ R R A
Sbjct: 800 GHLARRLAEHLRRIR-AAVVLQKHYRMQRARQA 831
Score = 35.4 bits (80), Expect = 0.20
Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 7/78 (8%)
Query: 582 RQWRAVML------IQAAIRSWLTRKHIQRLHAAATVIKRAWQKWRIRMACLAAKELDGV 635
R +R V++ IQ +R W+ R+H QRL AA VI+ A++ + R L A ++
Sbjct: 853 RTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRE-LKALRIEAR 911
Query: 636 EEKHFSQAPCSLSTSPLQ 653
+H + + +Q
Sbjct: 912 SAEHLKRLNVGMENKVVQ 929
>gi|194272142 myosin IXB isoform 2 [Homo sapiens]
Length = 2022
Score = 248 bits (632), Expect = 2e-65
Identities = 158/414 (38%), Positives = 238/414 (57%), Gaps = 29/414 (7%)
Query: 38 DDLTRVNPVTLETVLRCLQARYMADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHAAP 97
DDL + +T +L+ L+ R++ YT AG LVA+NPFK +P +Y+P+ ++ Y
Sbjct: 149 DDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLP-IYNPKYVKMYENQ- 206
Query: 98 QPQKLKPHVFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATSPA 157
Q KL+PHVF + + Y + L + VNQ IV+SGESG+GKT ++ L+ + + A S
Sbjct: 207 QLGKLEPHVFALADVAYYTM--LRKRVNQCIVISGESGSGKTQSTNFLI--HCLTALSQK 262
Query: 158 SWESHKIAERIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQT 217
+ A +E+ IL + PV+EAFGNA T NNNSSRFGKFIQ+ + + GA V+
Sbjct: 263 GY-----ASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEK 317
Query: 218 YLLEKTRVACQASSERNFHIFYQICKGASEDERLQWHLPEGAAFSWLPNPERSLE--EDC 275
YLLEK+R+ Q ERN+H+FY + G SE+ER ++ L + + +L +E ED
Sbjct: 318 YLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQHNLKIEDGEDL 377
Query: 276 ---FEVTREAMLHLGIDTPTQNNIFKVLAGLLHLGNIQF---AASEDEAQPCQPMDDAKY 329
FE ++AM +G T+ IF VL+ +L+LGN+ + A +E P +
Sbjct: 378 KHDFERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGLEVGPPE---- 433
Query: 330 SVRTAASLLGLPEDVLLEMVQIRTIRAGRQQQVFRKPCARAECDTRRDCLAKLIYARLFD 389
+ T + LL + ++L+E++ R + + P + +E T RD +AK +Y+ LFD
Sbjct: 434 VLDTLSQLLKVKREILVEVLTKRKTVTVNDKLIL--PYSLSEAITARDSMAKSLYSALFD 491
Query: 390 WLVSVINSSICADTDSWTTF----IGLLDVYGFESFPDNSLEQLCINYANEKLQ 439
W+V IN ++ D IG+LD++GFE F NS EQ CINYANE+LQ
Sbjct: 492 WIVLRINHALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQ 545
Score = 40.8 bits (94), Expect = 0.005
Identities = 40/199 (20%), Positives = 80/199 (40%), Gaps = 60/199 (30%)
Query: 427 EQLCINYANEKLQLEACGLVETIHISAAGFPIRVSHRNFVERYKLLRRLHPCTSSGPDSP 486
++LC + QL G++ET+ I +G+ + + ++F E++++L P
Sbjct: 860 KELCFDDELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTEQFQVLL---------PKDA 910
Query: 487 YPAKGLPEWCPHSEEATLEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHCGRTKVFMT 546
P + +I +L + + + I G+TKVF+
Sbjct: 911 QPCR---------------EVISTLLEKMKIDKRNYQI--------------GKTKVFLK 941
Query: 547 DSMLELLECGRARVLEQCARCIQGGWRRHRHREQERQWRAVMLIQAAIRSWLTRKHIQRL 606
++ + L+ HRE R+ ++L+Q+ R L R+H ++
Sbjct: 942 ETERQALQ-------------------ETLHREVVRK---ILLLQSWFRMVLERRHFLQM 979
Query: 607 HAAATVIKRAWQKWRIRMA 625
AA I+ W+ +R+R A
Sbjct: 980 KRAAVTIQACWRSYRVRRA 998
>gi|33356170 myosin IXB isoform 1 [Homo sapiens]
Length = 2157
Score = 248 bits (632), Expect = 2e-65
Identities = 158/414 (38%), Positives = 238/414 (57%), Gaps = 29/414 (7%)
Query: 38 DDLTRVNPVTLETVLRCLQARYMADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHAAP 97
DDL + +T +L+ L+ R++ YT AG LVA+NPFK +P +Y+P+ ++ Y
Sbjct: 149 DDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLP-IYNPKYVKMYENQ- 206
Query: 98 QPQKLKPHVFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATSPA 157
Q KL+PHVF + + Y + L + VNQ IV+SGESG+GKT ++ L+ + + A S
Sbjct: 207 QLGKLEPHVFALADVAYYTM--LRKRVNQCIVISGESGSGKTQSTNFLI--HCLTALSQK 262
Query: 158 SWESHKIAERIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQT 217
+ A +E+ IL + PV+EAFGNA T NNNSSRFGKFIQ+ + + GA V+
Sbjct: 263 GY-----ASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEK 317
Query: 218 YLLEKTRVACQASSERNFHIFYQICKGASEDERLQWHLPEGAAFSWLPNPERSLE--EDC 275
YLLEK+R+ Q ERN+H+FY + G SE+ER ++ L + + +L +E ED
Sbjct: 318 YLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQHNLKIEDGEDL 377
Query: 276 ---FEVTREAMLHLGIDTPTQNNIFKVLAGLLHLGNIQF---AASEDEAQPCQPMDDAKY 329
FE ++AM +G T+ IF VL+ +L+LGN+ + A +E P +
Sbjct: 378 KHDFERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGLEVGPPE---- 433
Query: 330 SVRTAASLLGLPEDVLLEMVQIRTIRAGRQQQVFRKPCARAECDTRRDCLAKLIYARLFD 389
+ T + LL + ++L+E++ R + + P + +E T RD +AK +Y+ LFD
Sbjct: 434 VLDTLSQLLKVKREILVEVLTKRKTVTVNDKLIL--PYSLSEAITARDSMAKSLYSALFD 491
Query: 390 WLVSVINSSICADTDSWTTF----IGLLDVYGFESFPDNSLEQLCINYANEKLQ 439
W+V IN ++ D IG+LD++GFE F NS EQ CINYANE+LQ
Sbjct: 492 WIVLRINHALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQ 545
Score = 40.8 bits (94), Expect = 0.005
Identities = 40/199 (20%), Positives = 80/199 (40%), Gaps = 60/199 (30%)
Query: 427 EQLCINYANEKLQLEACGLVETIHISAAGFPIRVSHRNFVERYKLLRRLHPCTSSGPDSP 486
++LC + QL G++ET+ I +G+ + + ++F E++++L P
Sbjct: 860 KELCFDDELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTEQFQVLL---------PKDA 910
Query: 487 YPAKGLPEWCPHSEEATLEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHCGRTKVFMT 546
P + +I +L + + + I G+TKVF+
Sbjct: 911 QPCR---------------EVISTLLEKMKIDKRNYQI--------------GKTKVFLK 941
Query: 547 DSMLELLECGRARVLEQCARCIQGGWRRHRHREQERQWRAVMLIQAAIRSWLTRKHIQRL 606
++ + L+ HRE R+ ++L+Q+ R L R+H ++
Sbjct: 942 ETERQALQ-------------------ETLHREVVRK---ILLLQSWFRMVLERRHFLQM 979
Query: 607 HAAATVIKRAWQKWRIRMA 625
AA I+ W+ +R+R A
Sbjct: 980 KRAAVTIQACWRSYRVRRA 998
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 247 bits (630), Expect = 3e-65
Identities = 145/408 (35%), Positives = 233/408 (57%), Gaps = 13/408 (3%)
Query: 36 KLDDLTRVNPVTLETVLRCLQARYMADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHA 95
K++D+ + + +VL L+ RY + YT +G V +NP+K +P +YS +++ Y
Sbjct: 86 KVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLP-IYSEKIVDMYKG 144
Query: 96 APQPQKLKPHVFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATS 155
+ ++ PH++ + + YR++ L + +QSI+ +GESGAGKT ++ ++++ AVVA+S
Sbjct: 145 KKR-HEMPPHIYAIADTAYRSM--LQDREDQSILCTGESGAGKTENTKKVIQYLAVVASS 201
Query: 156 PASWESHKIAERIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAV 215
+ I +E+++L +NP++EAFGNA T++N+NSSRFGKFI++ + + GA +
Sbjct: 202 HKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANI 261
Query: 216 QTYLLEKTRVACQASSERNFHIFYQICKGASEDERLQWHLPEGAAFSWLPNP----ERSL 271
+TYLLEK+R QA ER FHIFY + GA E R L +++L N +
Sbjct: 262 ETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPAAQ 321
Query: 272 EEDCFEVTREAMLHLGIDTPTQNNIFKVLAGLLHLGNIQFAASEDEAQPCQPMDDAKYSV 331
+++ F+ T EAM +G Q +I KV++ +L LGNI F + Q P + A V
Sbjct: 322 DDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKV 381
Query: 332 RTAASLLGLPEDVLLEMVQIRTIRAGRQQQVFRKPCARAECDTRRDCLAKLIYARLFDWL 391
L+G+ + I+ GR V +K + + D + LAK Y RLF W+
Sbjct: 382 ---CHLMGINVTDFTRSILTPRIKVGR--DVVQKAQTKEQADFAVEALAKATYERLFRWI 436
Query: 392 VSVINSSICADTDSWTTFIGLLDVYGFESFPDNSLEQLCINYANEKLQ 439
++ +N ++ +F+G+LD+ GFE F NS EQLCINY NEKLQ
Sbjct: 437 LTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQ 484
Score = 32.3 bits (72), Expect = 1.7
Identities = 42/199 (21%), Positives = 65/199 (32%), Gaps = 74/199 (37%)
Query: 439 QLEACGLVETIHISAAGFPIRVSHRNFVERYKLLRRLHPCTSSGPDSPYPAKGLPEWCPH 498
QL G++E I I GFP R+ + F +RY++L A +P+
Sbjct: 698 QLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEIL---------------AANAIPKGFMD 742
Query: 499 SEEATLEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHCGRTKVFMTDSMLELLECGRA 558
+ QA + + E P G++K+F +L
Sbjct: 743 GK-------------------QACILMIKALELDPNLYRIGQSKIFFRTGVL-------- 775
Query: 559 RVLEQCARCIQGGWRRHRHREQERQWR---AVMLIQAAIRSWLTRKHIQRLHAAATVIK- 614
H E+ER + +M QA R +L RK + T +K
Sbjct: 776 -----------------AHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKV 818
Query: 615 -----------RAWQKWRI 622
R WQ WR+
Sbjct: 819 IQRNCAAYLKLRNWQWWRL 837
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 247 bits (630), Expect = 3e-65
Identities = 145/408 (35%), Positives = 233/408 (57%), Gaps = 13/408 (3%)
Query: 36 KLDDLTRVNPVTLETVLRCLQARYMADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHA 95
K++D+ + + +VL L+ RY + YT +G V +NP+K +P +YS +++ Y
Sbjct: 86 KVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLP-IYSEKIVDMYKG 144
Query: 96 APQPQKLKPHVFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATS 155
+ ++ PH++ + + YR++ L + +QSI+ +GESGAGKT ++ ++++ AVVA+S
Sbjct: 145 KKR-HEMPPHIYAIADTAYRSM--LQDREDQSILCTGESGAGKTENTKKVIQYLAVVASS 201
Query: 156 PASWESHKIAERIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAV 215
+ I +E+++L +NP++EAFGNA T++N+NSSRFGKFI++ + + GA +
Sbjct: 202 HKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANI 261
Query: 216 QTYLLEKTRVACQASSERNFHIFYQICKGASEDERLQWHLPEGAAFSWLPNP----ERSL 271
+TYLLEK+R QA ER FHIFY + GA E R L +++L N +
Sbjct: 262 ETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPAAQ 321
Query: 272 EEDCFEVTREAMLHLGIDTPTQNNIFKVLAGLLHLGNIQFAASEDEAQPCQPMDDAKYSV 331
+++ F+ T EAM +G Q +I KV++ +L LGNI F + Q P + A V
Sbjct: 322 DDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKV 381
Query: 332 RTAASLLGLPEDVLLEMVQIRTIRAGRQQQVFRKPCARAECDTRRDCLAKLIYARLFDWL 391
L+G+ + I+ GR V +K + + D + LAK Y RLF W+
Sbjct: 382 ---CHLMGINVTDFTRSILTPRIKVGR--DVVQKAQTKEQADFAVEALAKATYERLFRWI 436
Query: 392 VSVINSSICADTDSWTTFIGLLDVYGFESFPDNSLEQLCINYANEKLQ 439
++ +N ++ +F+G+LD+ GFE F NS EQLCINY NEKLQ
Sbjct: 437 LTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQ 484
Score = 32.3 bits (72), Expect = 1.7
Identities = 42/199 (21%), Positives = 65/199 (32%), Gaps = 74/199 (37%)
Query: 439 QLEACGLVETIHISAAGFPIRVSHRNFVERYKLLRRLHPCTSSGPDSPYPAKGLPEWCPH 498
QL G++E I I GFP R+ + F +RY++L A +P+
Sbjct: 698 QLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEIL---------------AANAIPKGFMD 742
Query: 499 SEEATLEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHCGRTKVFMTDSMLELLECGRA 558
+ QA + + E P G++K+F +L
Sbjct: 743 GK-------------------QACILMIKALELDPNLYRIGQSKIFFRTGVL-------- 775
Query: 559 RVLEQCARCIQGGWRRHRHREQERQWR---AVMLIQAAIRSWLTRKHIQRLHAAATVIK- 614
H E+ER + +M QA R +L RK + T +K
Sbjct: 776 -----------------AHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKV 818
Query: 615 -----------RAWQKWRI 622
R WQ WR+
Sbjct: 819 IQRNCAAYLKLRNWQWWRL 837
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 246 bits (628), Expect = 6e-65
Identities = 149/408 (36%), Positives = 232/408 (56%), Gaps = 16/408 (3%)
Query: 36 KLDDLTRVNPVTLETVLRCLQARYMADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHA 95
K++D+ + + +VL L+ RY + YT +G V +NP+K +P +YS E++ Y
Sbjct: 82 KVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLP-IYSEEIVEMYKG 140
Query: 96 APQPQKLKPHVFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATS 155
+ ++ PH++ + + YR++ E +QSI+ +GESGAGKT ++ ++++ A VA+S
Sbjct: 141 KKR-HEMPPHIYAITDTAYRSMMQDRE--DQSILCTGESGAGKTENTKKVIQYLAYVASS 197
Query: 156 PASWESHKIAERIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAV 215
+S K +E+++L +NP++EAFGNA T++N+NSSRFGKFI++ + + GA +
Sbjct: 198 H---KSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANI 254
Query: 216 QTYLLEKTRVACQASSERNFHIFYQICKGASEDERLQWHLPEGAAFSWLPNPERSL---- 271
+TYLLEK+R QA ER FHIFY + GA E + L + +L N ++
Sbjct: 255 ETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSNGHVTIPGQQ 314
Query: 272 EEDCFEVTREAMLHLGIDTPTQNNIFKVLAGLLHLGNIQFAASEDEAQPCQPMDDAKYSV 331
++D F+ T EAM +GI Q + +V++G+L LGNI F + Q P + A V
Sbjct: 315 DKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKV 374
Query: 332 RTAASLLGLPEDVLLEMVQIRTIRAGRQQQVFRKPCARAECDTRRDCLAKLIYARLFDWL 391
+ LLG+ + I+ GR +K + + D + LAK Y R+F WL
Sbjct: 375 ---SHLLGINVTDFTRGILTPRIKVGR--DYVQKAQTKEQADFAIEALAKATYERMFRWL 429
Query: 392 VSVINSSICADTDSWTTFIGLLDVYGFESFPDNSLEQLCINYANEKLQ 439
V IN ++ +FIG+LD+ GFE F NS EQLCINY NEKLQ
Sbjct: 430 VLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQ 477
Score = 31.2 bits (69), Expect = 3.8
Identities = 15/34 (44%), Positives = 21/34 (61%)
Query: 439 QLEACGLVETIHISAAGFPIRVSHRNFVERYKLL 472
QL G++E I I GFP RV + F +RY++L
Sbjct: 691 QLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEIL 724
>gi|239582755 myosin IG [Homo sapiens]
Length = 1018
Score = 245 bits (626), Expect = 1e-64
Identities = 153/421 (36%), Positives = 229/421 (54%), Gaps = 25/421 (5%)
Query: 35 YKLDDLTRVNPVTLETVLRCLQARYMADTFYTNAGCTLVALNPFKPVPQLYSPELMREYH 94
Y D ++ VT+E +R LQ R+ YT G LV++NP++ +P LY PE + Y
Sbjct: 9 YGKPDFVLLDQVTMEDFMRNLQLRFEKGRIYTYIGEVLVSVNPYQELP-LYGPEAIARYQ 67
Query: 95 AAPQPQKLKPHVFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVAT 154
++ PH++ V Y+ +K + IV+SGESGAGKT S+ +M++ A V T
Sbjct: 68 GRELYER-PPHLYAVANAAYKAMKHRSR--DTCIVISGESGAGKTEASKHIMQYIAAV-T 123
Query: 155 SPASWESHKIAERIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAA 214
+P+ ER++ +L S V+EAFGNA T RN+NSSRFGK++ + + G
Sbjct: 124 NPSQRAE---VERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGH 180
Query: 215 VQTYLLEKTRVACQASSERNFHIFYQICKGASEDERLQWHLP----------EGAAFSWL 264
+ +YLLEK+RV Q ERNFH FYQ+ +G+ + + + HL +GA +
Sbjct: 181 IHSYLLEKSRVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMT 240
Query: 265 PNPERSLEEDCFEVTREAMLHLGIDTPTQNNIFKVLAGLLHLGNIQFAASEDEAQPCQPM 324
+ +E + EAM +G ++ ++LA +LHLGNI+F +E+ + +
Sbjct: 241 VHSALDSDEQSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEGGLQKEGL 300
Query: 325 DDAKYS-VRTAASLLGLPEDVLLEMVQIRTIRAGRQQQVFRKPCARAECDTRRDCLAKLI 383
A+ + V A L P D++L + RT+ +G +++ K AE RD AK +
Sbjct: 301 AVAEEALVDHVAELTATPRDLVLRSLLARTVASG-GRELIEKGHTAAEASYARDACAKAV 359
Query: 384 YARLFDWLVSVINSSI-----CADTDSWTTFIGLLDVYGFESFPDNSLEQLCINYANEKL 438
Y RLF+W+V+ INS + D T IG+LD+YGFE FP NS EQ CINY NEKL
Sbjct: 360 YQRLFEWVVNRINSVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKL 419
Query: 439 Q 439
Q
Sbjct: 420 Q 420
Score = 36.6 bits (83), Expect = 0.090
Identities = 41/169 (24%), Positives = 67/169 (39%), Gaps = 35/169 (20%)
Query: 439 QLEACGLVETIHISAAGFPIRVSHRNFVERYKLLRRLHPCTSSGPDSPYPAKGLPEWCPH 498
Q+ GL+E + + AGF R + F+ RYK+ C + P+
Sbjct: 621 QVAYLGLLENVRVRRAGFASRQPYSRFLLRYKMT-----CEYTWPNHLLG---------- 665
Query: 499 SEEATLEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHCGRTKVFM-TDSMLELLECGR 557
S++A + L++ + GD A G +K+F+ + L LE R
Sbjct: 666 SDKAAVSALLEQ-----------HGLQGDVA--------FGHSKLFIRSPRTLVTLEQSR 706
Query: 558 ARVLEQCARCIQGGWRRHRHREQERQWRAVMLIQAAIRSWLTRKHIQRL 606
AR++ +Q WR R + R+ RA+ I R R H+ L
Sbjct: 707 ARLIPIIVLLLQKAWRGTLARWRCRRLRAIYTIMRWFRRHKVRAHLAEL 755
>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
Length = 2175
Score = 245 bits (626), Expect = 1e-64
Identities = 155/417 (37%), Positives = 244/417 (58%), Gaps = 29/417 (6%)
Query: 34 LYKLDDLTRVNPVTLETVLRCLQARYMADTFYTNAGCTLVALNPFKPVPQLYSPELMREY 93
++ ++D+ R+ + +LR L RY YT G LVA+NP++ + +YSPE +R+Y
Sbjct: 64 VHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLL-SIYSPEHIRQY 122
Query: 94 HAAPQPQKLKPHVFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVA 153
+ ++ PH+F + + Y N+K +Q ++SGESGAGKT +++ +++F A ++
Sbjct: 123 -TNKKIGEMPPHIFAIADNCYFNMKR--NSRDQCCIISGESGAGKTESTKLILQFLAAIS 179
Query: 154 TSPASWESHKIAERIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGA 213
SW IEQ++L + P++EAFGNA T+RN+NSSRFGK+I + N+ + GA
Sbjct: 180 -GQHSW--------IEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGA 230
Query: 214 AVQTYLLEKTRVACQASSERNFHIFYQICKGASEDERLQWHLPEGAAFSWLP-----NPE 268
++ YLLEK+RV QA ERN+H+FY + +G SED++ + L + + +++L E
Sbjct: 231 KIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCE 290
Query: 269 RSLEEDCFEVTREAMLHLGIDTPTQN-NIFKVLAGLLHLGNIQF-AASEDEAQPCQPMDD 326
++ + R AM L + T T+N I K+LA +LHLGN+Q+ A + + C+ +
Sbjct: 291 GRVDSQEYANIRSAMKVL-MFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFS 349
Query: 327 AKYSVRTAASLLGLPEDVLLEMVQIRTIRAGRQQQVFRKPCARAECDTRRDCLAKLIYAR 386
S+ TAASLL + L+ + RT+ + + P +R + RD K IY R
Sbjct: 350 P--SLATAASLLEVNPPDLMSCLTSRTLIT--RGETVSTPLSREQALDVRDAFVKGIYGR 405
Query: 387 LFDWLVSVINSSI----CADTDSWTTFIGLLDVYGFESFPDNSLEQLCINYANEKLQ 439
LF W+V IN++I D + IGLLD++GFE+F NS EQLCIN+ANE LQ
Sbjct: 406 LFVWIVDKINAAIYKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQ 462
Score = 50.8 bits (120), Expect = 5e-06
Identities = 49/180 (27%), Positives = 72/180 (40%), Gaps = 55/180 (30%)
Query: 439 QLEACGLVETIHISAAGFPIRVSHRNFVERYKLLRRLHPCTSSGPDSPYPAKGLPEWCPH 498
QL G++ETI I AG+PIR S FVERY++L LP P
Sbjct: 655 QLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVL-------------------LPGVKPA 695
Query: 499 SEEATLEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHCGRTKVFMTDSMLELLECGRA 558
++ D+ T + +A T D G+TK+F+ D LLE R
Sbjct: 696 YKQG-------DLRGTCQRMAEAVLGTHDD-------WQIGKTKIFLKDHHDMLLEVERD 741
Query: 559 RVLEQCARCIQGGWRRHRHREQERQWRAVMLIQAAIRSWLTRKHIQRLHAAATVIKRAWQ 618
+ + V+L+Q IR + R + +L AAT+I+R W+
Sbjct: 742 KAITD----------------------RVILLQKVIRGFKDRSNFLKLKNAATLIQRHWR 779
>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
Length = 1204
Score = 245 bits (626), Expect = 1e-64
Identities = 155/417 (37%), Positives = 244/417 (58%), Gaps = 29/417 (6%)
Query: 34 LYKLDDLTRVNPVTLETVLRCLQARYMADTFYTNAGCTLVALNPFKPVPQLYSPELMREY 93
++ ++D+ R+ + +LR L RY YT G LVA+NP++ + +YSPE +R+Y
Sbjct: 64 VHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLL-SIYSPEHIRQY 122
Query: 94 HAAPQPQKLKPHVFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVA 153
+ ++ PH+F + + Y N+K +Q ++SGESGAGKT +++ +++F A ++
Sbjct: 123 -TNKKIGEMPPHIFAIADNCYFNMKR--NSRDQCCIISGESGAGKTESTKLILQFLAAIS 179
Query: 154 TSPASWESHKIAERIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGA 213
SW IEQ++L + P++EAFGNA T+RN+NSSRFGK+I + N+ + GA
Sbjct: 180 -GQHSW--------IEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGA 230
Query: 214 AVQTYLLEKTRVACQASSERNFHIFYQICKGASEDERLQWHLPEGAAFSWLP-----NPE 268
++ YLLEK+RV QA ERN+H+FY + +G SED++ + L + + +++L E
Sbjct: 231 KIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCE 290
Query: 269 RSLEEDCFEVTREAMLHLGIDTPTQN-NIFKVLAGLLHLGNIQF-AASEDEAQPCQPMDD 326
++ + R AM L + T T+N I K+LA +LHLGN+Q+ A + + C+ +
Sbjct: 291 GRVDSQEYANIRSAMKVL-MFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFS 349
Query: 327 AKYSVRTAASLLGLPEDVLLEMVQIRTIRAGRQQQVFRKPCARAECDTRRDCLAKLIYAR 386
S+ TAASLL + L+ + RT+ + + P +R + RD K IY R
Sbjct: 350 P--SLATAASLLEVNPPDLMSCLTSRTLIT--RGETVSTPLSREQALDVRDAFVKGIYGR 405
Query: 387 LFDWLVSVINSSI----CADTDSWTTFIGLLDVYGFESFPDNSLEQLCINYANEKLQ 439
LF W+V IN++I D + IGLLD++GFE+F NS EQLCIN+ANE LQ
Sbjct: 406 LFVWIVDKINAAIYKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQ 462
Score = 50.8 bits (120), Expect = 5e-06
Identities = 49/180 (27%), Positives = 72/180 (40%), Gaps = 55/180 (30%)
Query: 439 QLEACGLVETIHISAAGFPIRVSHRNFVERYKLLRRLHPCTSSGPDSPYPAKGLPEWCPH 498
QL G++ETI I AG+PIR S FVERY++L LP P
Sbjct: 655 QLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVL-------------------LPGVKPA 695
Query: 499 SEEATLEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHCGRTKVFMTDSMLELLECGRA 558
++ D+ T + +A T D G+TK+F+ D LLE R
Sbjct: 696 YKQG-------DLRGTCQRMAEAVLGTHDD-------WQIGKTKIFLKDHHDMLLEVERD 741
Query: 559 RVLEQCARCIQGGWRRHRHREQERQWRAVMLIQAAIRSWLTRKHIQRLHAAATVIKRAWQ 618
+ + V+L+Q IR + R + +L AAT+I+R W+
Sbjct: 742 KAITD----------------------RVILLQKVIRGFKDRSNFLKLKNAATLIQRHWR 779
>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
Length = 2215
Score = 245 bits (626), Expect = 1e-64
Identities = 155/417 (37%), Positives = 244/417 (58%), Gaps = 29/417 (6%)
Query: 34 LYKLDDLTRVNPVTLETVLRCLQARYMADTFYTNAGCTLVALNPFKPVPQLYSPELMREY 93
++ ++D+ R+ + +LR L RY YT G LVA+NP++ + +YSPE +R+Y
Sbjct: 64 VHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLL-SIYSPEHIRQY 122
Query: 94 HAAPQPQKLKPHVFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVA 153
+ ++ PH+F + + Y N+K +Q ++SGESGAGKT +++ +++F A ++
Sbjct: 123 -TNKKIGEMPPHIFAIADNCYFNMKR--NSRDQCCIISGESGAGKTESTKLILQFLAAIS 179
Query: 154 TSPASWESHKIAERIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGA 213
SW IEQ++L + P++EAFGNA T+RN+NSSRFGK+I + N+ + GA
Sbjct: 180 -GQHSW--------IEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGA 230
Query: 214 AVQTYLLEKTRVACQASSERNFHIFYQICKGASEDERLQWHLPEGAAFSWLP-----NPE 268
++ YLLEK+RV QA ERN+H+FY + +G SED++ + L + + +++L E
Sbjct: 231 KIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCE 290
Query: 269 RSLEEDCFEVTREAMLHLGIDTPTQN-NIFKVLAGLLHLGNIQF-AASEDEAQPCQPMDD 326
++ + R AM L + T T+N I K+LA +LHLGN+Q+ A + + C+ +
Sbjct: 291 GRVDSQEYANIRSAMKVL-MFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFS 349
Query: 327 AKYSVRTAASLLGLPEDVLLEMVQIRTIRAGRQQQVFRKPCARAECDTRRDCLAKLIYAR 386
S+ TAASLL + L+ + RT+ + + P +R + RD K IY R
Sbjct: 350 P--SLATAASLLEVNPPDLMSCLTSRTLIT--RGETVSTPLSREQALDVRDAFVKGIYGR 405
Query: 387 LFDWLVSVINSSI----CADTDSWTTFIGLLDVYGFESFPDNSLEQLCINYANEKLQ 439
LF W+V IN++I D + IGLLD++GFE+F NS EQLCIN+ANE LQ
Sbjct: 406 LFVWIVDKINAAIYKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQ 462
Score = 50.8 bits (120), Expect = 5e-06
Identities = 49/180 (27%), Positives = 72/180 (40%), Gaps = 55/180 (30%)
Query: 439 QLEACGLVETIHISAAGFPIRVSHRNFVERYKLLRRLHPCTSSGPDSPYPAKGLPEWCPH 498
QL G++ETI I AG+PIR S FVERY++L LP P
Sbjct: 655 QLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVL-------------------LPGVKPA 695
Query: 499 SEEATLEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHCGRTKVFMTDSMLELLECGRA 558
++ D+ T + +A T D G+TK+F+ D LLE R
Sbjct: 696 YKQG-------DLRGTCQRMAEAVLGTHDD-------WQIGKTKIFLKDHHDMLLEVERD 741
Query: 559 RVLEQCARCIQGGWRRHRHREQERQWRAVMLIQAAIRSWLTRKHIQRLHAAATVIKRAWQ 618
+ + V+L+Q IR + R + +L AAT+I+R W+
Sbjct: 742 KAITD----------------------RVILLQKVIRGFKDRSNFLKLKNAATLIQRHWR 779
>gi|156119615 myosin IXA [Homo sapiens]
Length = 2548
Score = 243 bits (621), Expect = 4e-64
Identities = 159/433 (36%), Positives = 235/433 (54%), Gaps = 50/433 (11%)
Query: 38 DDLTRVNPVTLETVLRCLQARYMADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHAAP 97
DDL + + +T+L L+ R+ + YT G L+ +NPFK +P +Y+P+ ++ Y
Sbjct: 149 DDLCSLPDLNEKTLLENLRNRFKHEKIYTYVGSILIVINPFKFLP-IYNPKYVKMYDNH- 206
Query: 98 QPQKLKPHVFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATSPA 157
Q KL+PH++ V + Y + L NQ IV+SGESG+GKT ++ L+ ++
Sbjct: 207 QLGKLEPHIYAVADVAYHAM--LQRKKNQCIVISGESGSGKTQSTNFLIHHLTALSQKG- 263
Query: 158 SWESHKIAERIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQT 217
A +EQ IL + PV+EAFGNA T NNNSSRFGKFIQ+ + GA V+
Sbjct: 264 ------FASGVEQIILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNYQETGTVLGAYVEK 317
Query: 218 YLLEKTRVACQASSERNFHIFYQICKGASEDERLQWHLPEGAAFSWL----PNPER---- 269
YLLEK+R+ Q +ERN+H+FY + GASEDER +HL + + +L P R
Sbjct: 318 YLLEKSRLVYQEHNERNYHVFYYLLAGASEDERSAFHLKQPEEYHYLNQITKKPLRQSWD 377
Query: 270 ----SLEEDCFEVTREAMLH-----------LGIDTPTQNNIFKVLAGLLHLGNIQFAAS 314
E DCF V E + H +G T+ IF +L+ +LHLGNI +
Sbjct: 378 DYCYDSEPDCFTVEGEDLRHDFERLQLAMEMVGFLPKTRRQIFSLLSAILHLGNICYKKK 437
Query: 315 ---EDEAQPCQPMDDAKYSVRTAASLLGLPEDVLLE-MVQIRTIRAGRQQQVFRKPCARA 370
+D C P + + LL + E++L E +V +T+ G + + P A
Sbjct: 438 TYRDDSIDICNP-----EVLPIVSELLEVKEEMLFEALVTRKTVTVGEKLIL---PYKLA 489
Query: 371 ECDTRRDCLAKLIYARLFDWLVSVINSSICADTD----SWTTFIGLLDVYGFESFPDNSL 426
E T R+ +AK +Y+ LFDW+V IN ++ D + T IG+LD++GFE + +NS
Sbjct: 490 EAVTVRNSMAKSLYSALFDWIVFRINHALLNSKDLEHNTKTLSIGVLDIFGFEDYENNSF 549
Query: 427 EQLCINYANEKLQ 439
EQ CIN+ANE+LQ
Sbjct: 550 EQFCINFANERLQ 562
Score = 37.0 bits (84), Expect = 0.069
Identities = 50/231 (21%), Positives = 91/231 (39%), Gaps = 55/231 (23%)
Query: 439 QLEACGLVETIHISAAGFPIRVSHRNFVERYKLL--RRLHPCTSS----------GPDSP 486
QL G++ET+ I +G+ + S ++FV + +L R + P + PD+
Sbjct: 935 QLRYTGMLETVRIRQSGYSSKYSFQDFVSHFHVLLPRNIIPSKFNIQDFFRKINLNPDNY 994
Query: 487 YPAKGLPEWCPHSEEATLEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHCGRTKVFMT 546
K + + + L Q++L ++ +
Sbjct: 995 QVGKTMVFLKEQERQHLQDLLHQEVLR----------------------------RIILL 1026
Query: 547 DSMLELLECGRARV-LEQCARCIQGGWRRHRHREQERQWR----------AVMLIQAAIR 595
+L C + + L Q + IQ WR + +++Q R A L+QA+ R
Sbjct: 1027 QRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQKQVRDAAVQKDAFVMASAAALLQASWR 1086
Query: 596 SWLTRKHIQRLHAAATVIKRAWQKW--RIRMA--CLAAKELDGVEEKHFSQ 642
+ L R+ L AAA VI++ W+ + R MA C+ A+ E K + +
Sbjct: 1087 AHLERQRYLELRAAAIVIQQKWRDYYRRRHMAAICIQARWKAYRESKRYQE 1137
>gi|194328685 myosin IB isoform 1 [Homo sapiens]
Length = 1136
Score = 242 bits (618), Expect = 8e-64
Identities = 146/406 (35%), Positives = 225/406 (55%), Gaps = 17/406 (4%)
Query: 39 DLTRVNPVTLETVLRCLQARYMADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHAAPQ 98
D+ + P+ ET + L+ R+ YT G ++++NP++ +P +YSPE + EY
Sbjct: 19 DMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLP-IYSPEKVEEYRNR-N 76
Query: 99 PQKLKPHVFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATSPAS 158
+L PH+F + ++ YR+++ + +Q I+++GESGAGKT S+ +M + A V A
Sbjct: 77 FYELSPHIFALSDEAYRSLRD--QDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAE 134
Query: 159 WESHKIAERIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQTY 218
++++++L SNPV+EAFGNA T+RN+NSSRFGK++ ++ + G + Y
Sbjct: 135 ------VNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNY 188
Query: 219 LLEKTRVACQASSERNFHIFYQICKGASEDERLQWHLP-EGAAFSWLPNPERSLE--EDC 275
LLEK+RV Q ERNFH+FYQ+ GASE+ + L + + +++L + +D
Sbjct: 189 LLEKSRVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSAKVNGVDDA 248
Query: 276 --FEVTREAMLHLGIDTPTQNNIFKVLAGLLHLGNIQFAASEDEAQPCQPMDDAKYSVRT 333
F R AM +G ++ V+A +L LGNI+F + K ++
Sbjct: 249 ANFRTVRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKE 308
Query: 334 AASLLGLPEDVLLEMVQIRTIRAGRQQQVFRKPCARAECDTRRDCLAKLIYARLFDWLVS 393
L G+ + VL RT+ A +Q+ A+ RD LAK +Y+RLF WLV+
Sbjct: 309 ICELTGIDQSVLERAFSFRTVEA--KQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVN 366
Query: 394 VINSSICADTDSWTTFIGLLDVYGFESFPDNSLEQLCINYANEKLQ 439
IN SI A T +G+LD+YGFE F DNS EQ INY NEKLQ
Sbjct: 367 RINESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQ 412
Score = 40.0 bits (92), Expect = 0.008
Identities = 56/238 (23%), Positives = 95/238 (39%), Gaps = 48/238 (20%)
Query: 439 QLEACGLVETIHISAAGFPIRVSHRNFVERYKLLRRLHPCTSSGPDSPYPAKGLPEWCPH 498
Q+ GL+E + + AG+ R ++ +ERYK+L C + P PA+
Sbjct: 615 QIRYLGLLENVRVRRAGYAFRQAYEPCLERYKML-----CKQTWPHWKGPAR-------- 661
Query: 499 SEEATLEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHCGRTKVFMTD-SMLELLECGR 557
+ +E L ++ +PV GR+K+F+ + L LE R
Sbjct: 662 ---SGVEVLFNEL--EIPV----------------EEYSFGRSKIFIRNPRTLFKLEDLR 700
Query: 558 ARVLEQCARCIQ---GGWRRHRHREQERQWRAVMLIQAAIRSWLTRKHIQRLHAAATVIK 614
+ LE A IQ GW+ H + ++ ++I A R + +K Q+ ++A VI+
Sbjct: 701 KQRLEDLATLIQKIYRGWKCRTHFLLMK--KSQIVIAAWYRRYAQQKRYQQTKSSALVIQ 758
Query: 615 RAWQKWRIRMACLAAKELDGVEEK--------HFSQAPCSLSTSPLQTRLLEAIIRLW 664
+ W+ R K +E H +QA L + R AI +W
Sbjct: 759 SYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQARRELRRLKEEARNKHAIAVIW 816
>gi|44889481 myosin IB isoform 2 [Homo sapiens]
Length = 1078
Score = 242 bits (618), Expect = 8e-64
Identities = 146/406 (35%), Positives = 225/406 (55%), Gaps = 17/406 (4%)
Query: 39 DLTRVNPVTLETVLRCLQARYMADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHAAPQ 98
D+ + P+ ET + L+ R+ YT G ++++NP++ +P +YSPE + EY
Sbjct: 19 DMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLP-IYSPEKVEEYRNR-N 76
Query: 99 PQKLKPHVFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATSPAS 158
+L PH+F + ++ YR+++ + +Q I+++GESGAGKT S+ +M + A V A
Sbjct: 77 FYELSPHIFALSDEAYRSLRD--QDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAE 134
Query: 159 WESHKIAERIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQTY 218
++++++L SNPV+EAFGNA T+RN+NSSRFGK++ ++ + G + Y
Sbjct: 135 ------VNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNY 188
Query: 219 LLEKTRVACQASSERNFHIFYQICKGASEDERLQWHLP-EGAAFSWLPNPERSLE--EDC 275
LLEK+RV Q ERNFH+FYQ+ GASE+ + L + + +++L + +D
Sbjct: 189 LLEKSRVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSAKVNGVDDA 248
Query: 276 --FEVTREAMLHLGIDTPTQNNIFKVLAGLLHLGNIQFAASEDEAQPCQPMDDAKYSVRT 333
F R AM +G ++ V+A +L LGNI+F + K ++
Sbjct: 249 ANFRTVRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKE 308
Query: 334 AASLLGLPEDVLLEMVQIRTIRAGRQQQVFRKPCARAECDTRRDCLAKLIYARLFDWLVS 393
L G+ + VL RT+ A +Q+ A+ RD LAK +Y+RLF WLV+
Sbjct: 309 ICELTGIDQSVLERAFSFRTVEA--KQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVN 366
Query: 394 VINSSICADTDSWTTFIGLLDVYGFESFPDNSLEQLCINYANEKLQ 439
IN SI A T +G+LD+YGFE F DNS EQ INY NEKLQ
Sbjct: 367 RINESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQ 412
Score = 40.0 bits (92), Expect = 0.008
Identities = 54/216 (25%), Positives = 86/216 (39%), Gaps = 65/216 (30%)
Query: 439 QLEACGLVETIHISAAGFPIRVSHRNFVERYKLLRRLHPCTSSGPDSPYPAKGLPEWCPH 498
Q+ GL+E + + AG+ R ++ +ERYK+L C + P PA+
Sbjct: 615 QIRYLGLLENVRVRRAGYAFRQAYEPCLERYKML-----CKQTWPHWKGPAR-------- 661
Query: 499 SEEATLEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHCGRTKVFMTD-SMLELLECGR 557
+ +E L ++ +PV GR+K+F+ + L LE R
Sbjct: 662 ---SGVEVLFNEL--EIPV----------------EEYSFGRSKIFIRNPRTLFKLEDLR 700
Query: 558 ARVLEQCARCIQ---GGW--RRH----------------RHREQERQWR---AVMLIQAA 593
+ LE A IQ GW R H R+ +Q+R + + ++IQ+
Sbjct: 701 KQRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSY 760
Query: 594 IRSWLTR------KHIQRLHAAATVIKRAWQKWRIR 623
IR W R KH +R A T I W ++R
Sbjct: 761 IRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQVR 796
>gi|240120050 myosin IB isoform 1 [Homo sapiens]
Length = 1136
Score = 242 bits (618), Expect = 8e-64
Identities = 146/406 (35%), Positives = 225/406 (55%), Gaps = 17/406 (4%)
Query: 39 DLTRVNPVTLETVLRCLQARYMADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHAAPQ 98
D+ + P+ ET + L+ R+ YT G ++++NP++ +P +YSPE + EY
Sbjct: 19 DMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLP-IYSPEKVEEYRNR-N 76
Query: 99 PQKLKPHVFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATSPAS 158
+L PH+F + ++ YR+++ + +Q I+++GESGAGKT S+ +M + A V A
Sbjct: 77 FYELSPHIFALSDEAYRSLRD--QDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAE 134
Query: 159 WESHKIAERIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQTY 218
++++++L SNPV+EAFGNA T+RN+NSSRFGK++ ++ + G + Y
Sbjct: 135 ------VNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNY 188
Query: 219 LLEKTRVACQASSERNFHIFYQICKGASEDERLQWHLP-EGAAFSWLPNPERSLE--EDC 275
LLEK+RV Q ERNFH+FYQ+ GASE+ + L + + +++L + +D
Sbjct: 189 LLEKSRVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSAKVNGVDDA 248
Query: 276 --FEVTREAMLHLGIDTPTQNNIFKVLAGLLHLGNIQFAASEDEAQPCQPMDDAKYSVRT 333
F R AM +G ++ V+A +L LGNI+F + K ++
Sbjct: 249 ANFRTVRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKE 308
Query: 334 AASLLGLPEDVLLEMVQIRTIRAGRQQQVFRKPCARAECDTRRDCLAKLIYARLFDWLVS 393
L G+ + VL RT+ A +Q+ A+ RD LAK +Y+RLF WLV+
Sbjct: 309 ICELTGIDQSVLERAFSFRTVEA--KQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVN 366
Query: 394 VINSSICADTDSWTTFIGLLDVYGFESFPDNSLEQLCINYANEKLQ 439
IN SI A T +G+LD+YGFE F DNS EQ INY NEKLQ
Sbjct: 367 RINESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQ 412
Score = 40.0 bits (92), Expect = 0.008
Identities = 56/238 (23%), Positives = 95/238 (39%), Gaps = 48/238 (20%)
Query: 439 QLEACGLVETIHISAAGFPIRVSHRNFVERYKLLRRLHPCTSSGPDSPYPAKGLPEWCPH 498
Q+ GL+E + + AG+ R ++ +ERYK+L C + P PA+
Sbjct: 615 QIRYLGLLENVRVRRAGYAFRQAYEPCLERYKML-----CKQTWPHWKGPAR-------- 661
Query: 499 SEEATLEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHCGRTKVFMTD-SMLELLECGR 557
+ +E L ++ +PV GR+K+F+ + L LE R
Sbjct: 662 ---SGVEVLFNEL--EIPV----------------EEYSFGRSKIFIRNPRTLFKLEDLR 700
Query: 558 ARVLEQCARCIQ---GGWRRHRHREQERQWRAVMLIQAAIRSWLTRKHIQRLHAAATVIK 614
+ LE A IQ GW+ H + ++ ++I A R + +K Q+ ++A VI+
Sbjct: 701 KQRLEDLATLIQKIYRGWKCRTHFLLMK--KSQIVIAAWYRRYAQQKRYQQTKSSALVIQ 758
Query: 615 RAWQKWRIRMACLAAKELDGVEEK--------HFSQAPCSLSTSPLQTRLLEAIIRLW 664
+ W+ R K +E H +QA L + R AI +W
Sbjct: 759 SYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQARRELRRLKEEARNKHAIAVIW 816
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 241 bits (616), Expect = 1e-63
Identities = 147/410 (35%), Positives = 229/410 (55%), Gaps = 17/410 (4%)
Query: 36 KLDDLTRVNPVTLETVLRCLQARYMADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHA 95
K++D+ + + +VL L+ RY + YT +G V +NP+K +P +YS ++ Y
Sbjct: 86 KVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLP-IYSENIIEMYRG 144
Query: 96 APQPQKLKPHVFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATS 155
+ ++ PH++ + E YR + L + +QSI+ +GESGAGKT ++ ++++ A VA+S
Sbjct: 145 KKR-HEMPPHIYAISESAYRCM--LQDREDQSILCTGESGAGKTENTKKVIQYLAHVASS 201
Query: 156 PASWESHKIAERIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAV 215
+ H I +E+++L +NP++E+FGNA T++N+NSSRFGKFI++ + + GA +
Sbjct: 202 HKGRKDHNIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANI 261
Query: 216 QTYLLEKTRVACQASSERNFHIFYQICKGASEDERLQWHLPEG------AAFSWLPNPER 269
+TYLLEK+R QA ER FHIFYQ+ GA E + L EG + ++P P +
Sbjct: 262 ETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDL-LLEGFNNYRFLSNGYIPIPGQ 320
Query: 270 SLEEDCFEVTREAMLHLGIDTPTQNNIFKVLAGLLHLGNIQFAASEDEAQPCQPMDDAKY 329
++D F+ T EAM +G ++ KV++ +L GNI F + Q P +
Sbjct: 321 Q-DKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTV-- 377
Query: 330 SVRTAASLLGLPEDVLLEMVQIRTIRAGRQQQVFRKPCARAECDTRRDCLAKLIYARLFD 389
+ LLG+ + I+ GR +K + + D + LAK Y RLF
Sbjct: 378 -AQKLCHLLGMNVMEFTRAILTPRIKVGR--DYVQKAQTKEQADFAVEALAKATYERLFR 434
Query: 390 WLVSVINSSICADTDSWTTFIGLLDVYGFESFPDNSLEQLCINYANEKLQ 439
WLV IN ++ +FIG+LD+ GFE F NS EQLCINY NEKLQ
Sbjct: 435 WLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQ 484
Score = 30.8 bits (68), Expect = 5.0
Identities = 14/34 (41%), Positives = 21/34 (61%)
Query: 439 QLEACGLVETIHISAAGFPIRVSHRNFVERYKLL 472
QL G++E I I GFP R+ + F +RY++L
Sbjct: 698 QLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEIL 731
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 241 bits (616), Expect = 1e-63
Identities = 145/415 (34%), Positives = 234/415 (56%), Gaps = 20/415 (4%)
Query: 36 KLDDLTRVNPVTLETVLRCLQARYMADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHA 95
K++D+ + + +VL L+ RY + YT +G V +NP+K +P +YS +++ Y
Sbjct: 86 KVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLP-IYSEKIVDMYKG 144
Query: 96 APQPQKLKPHVFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATS 155
+ ++ PH++ + + YR++ L + +QSI+ +GESGAGKT ++ ++++ AVVA+S
Sbjct: 145 KKR-HEMPPHIYAIADTAYRSM--LQDREDQSILCTGESGAGKTENTKKVIQYLAVVASS 201
Query: 156 PASWESHKIAE-------RIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQ 208
+ I + +E+++L +NP++EAFGNA T++N+NSSRFGKFI++ +
Sbjct: 202 HKGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTG 261
Query: 209 QMTGAAVQTYLLEKTRVACQASSERNFHIFYQICKGASEDERLQWHLPEGAAFSWLPNP- 267
+ GA ++TYLLEK+R QA ER FHIFY + GA E R L +++L N
Sbjct: 262 YIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGF 321
Query: 268 ---ERSLEEDCFEVTREAMLHLGIDTPTQNNIFKVLAGLLHLGNIQFAASEDEAQPCQPM 324
+ +++ F+ T EAM +G Q +I KV++ +L LGNI F + Q P
Sbjct: 322 VPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPD 381
Query: 325 DDAKYSVRTAASLLGLPEDVLLEMVQIRTIRAGRQQQVFRKPCARAECDTRRDCLAKLIY 384
+ A V L+G+ + I+ GR V +K + + D + LAK Y
Sbjct: 382 NTAAQKV---CHLMGINVTDFTRSILTPRIKVGR--DVVQKAQTKEQADFAVEALAKATY 436
Query: 385 ARLFDWLVSVINSSICADTDSWTTFIGLLDVYGFESFPDNSLEQLCINYANEKLQ 439
RLF W+++ +N ++ +F+G+LD+ GFE F NS EQLCINY NEKLQ
Sbjct: 437 ERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQ 491
Score = 32.3 bits (72), Expect = 1.7
Identities = 42/199 (21%), Positives = 65/199 (32%), Gaps = 74/199 (37%)
Query: 439 QLEACGLVETIHISAAGFPIRVSHRNFVERYKLLRRLHPCTSSGPDSPYPAKGLPEWCPH 498
QL G++E I I GFP R+ + F +RY++L A +P+
Sbjct: 705 QLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEIL---------------AANAIPKGFMD 749
Query: 499 SEEATLEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHCGRTKVFMTDSMLELLECGRA 558
+ QA + + E P G++K+F +L
Sbjct: 750 GK-------------------QACILMIKALELDPNLYRIGQSKIFFRTGVL-------- 782
Query: 559 RVLEQCARCIQGGWRRHRHREQERQWR---AVMLIQAAIRSWLTRKHIQRLHAAATVIK- 614
H E+ER + +M QA R +L RK + T +K
Sbjct: 783 -----------------AHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKV 825
Query: 615 -----------RAWQKWRI 622
R WQ WR+
Sbjct: 826 IQRNCAAYLKLRNWQWWRL 844
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 241 bits (616), Expect = 1e-63
Identities = 145/415 (34%), Positives = 234/415 (56%), Gaps = 20/415 (4%)
Query: 36 KLDDLTRVNPVTLETVLRCLQARYMADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHA 95
K++D+ + + +VL L+ RY + YT +G V +NP+K +P +YS +++ Y
Sbjct: 86 KVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLP-IYSEKIVDMYKG 144
Query: 96 APQPQKLKPHVFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATS 155
+ ++ PH++ + + YR++ L + +QSI+ +GESGAGKT ++ ++++ AVVA+S
Sbjct: 145 KKR-HEMPPHIYAIADTAYRSM--LQDREDQSILCTGESGAGKTENTKKVIQYLAVVASS 201
Query: 156 PASWESHKIAE-------RIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQ 208
+ I + +E+++L +NP++EAFGNA T++N+NSSRFGKFI++ +
Sbjct: 202 HKGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTG 261
Query: 209 QMTGAAVQTYLLEKTRVACQASSERNFHIFYQICKGASEDERLQWHLPEGAAFSWLPNP- 267
+ GA ++TYLLEK+R QA ER FHIFY + GA E R L +++L N
Sbjct: 262 YIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGF 321
Query: 268 ---ERSLEEDCFEVTREAMLHLGIDTPTQNNIFKVLAGLLHLGNIQFAASEDEAQPCQPM 324
+ +++ F+ T EAM +G Q +I KV++ +L LGNI F + Q P
Sbjct: 322 VPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPD 381
Query: 325 DDAKYSVRTAASLLGLPEDVLLEMVQIRTIRAGRQQQVFRKPCARAECDTRRDCLAKLIY 384
+ A V L+G+ + I+ GR V +K + + D + LAK Y
Sbjct: 382 NTAAQKV---CHLMGINVTDFTRSILTPRIKVGR--DVVQKAQTKEQADFAVEALAKATY 436
Query: 385 ARLFDWLVSVINSSICADTDSWTTFIGLLDVYGFESFPDNSLEQLCINYANEKLQ 439
RLF W+++ +N ++ +F+G+LD+ GFE F NS EQLCINY NEKLQ
Sbjct: 437 ERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQ 491
Score = 32.3 bits (72), Expect = 1.7
Identities = 42/199 (21%), Positives = 65/199 (32%), Gaps = 74/199 (37%)
Query: 439 QLEACGLVETIHISAAGFPIRVSHRNFVERYKLLRRLHPCTSSGPDSPYPAKGLPEWCPH 498
QL G++E I I GFP R+ + F +RY++L A +P+
Sbjct: 705 QLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEIL---------------AANAIPKGFMD 749
Query: 499 SEEATLEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHCGRTKVFMTDSMLELLECGRA 558
+ QA + + E P G++K+F +L
Sbjct: 750 GK-------------------QACILMIKALELDPNLYRIGQSKIFFRTGVL-------- 782
Query: 559 RVLEQCARCIQGGWRRHRHREQERQWR---AVMLIQAAIRSWLTRKHIQRLHAAATVIK- 614
H E+ER + +M QA R +L RK + T +K
Sbjct: 783 -----------------AHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKV 825
Query: 615 -----------RAWQKWRI 622
R WQ WR+
Sbjct: 826 IQRNCAAYLKLRNWQWWRL 844
>gi|55956916 myosin IE [Homo sapiens]
Length = 1108
Score = 239 bits (609), Expect = 9e-63
Identities = 144/411 (35%), Positives = 232/411 (56%), Gaps = 26/411 (6%)
Query: 37 LDDLTRVNPVTLETVLRCLQARYMADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHAA 96
+DD+ ++ +T +++ L+ RYM D +T G L+++NPFK +P E+ Y A
Sbjct: 21 VDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEI-EMYQGA 79
Query: 97 PQPQKLKPHVFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATSP 156
Q + PH++ + + YRN+ +I+ NQ +++SGESGAGKT ++ +M + + V+
Sbjct: 80 AQYEN-PPHIYALADNMYRNM--IIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGGG 136
Query: 157 ASWESHKIAERIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQ 216
+ ++ IL SNP++EAFGNA T+RNNNSSRFGK+ ++Q + + G +
Sbjct: 137 TK------VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKIS 190
Query: 217 TYLLEKTRVACQASSERNFHIFYQICKGASEDERLQWHLPEGAAFSWLPNPERSLEEDC- 275
+LLEK+RV + ER+FHIFYQ+ +GAS +++ + + +L +D
Sbjct: 191 NFLLEKSRVVMRNPGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSLSGSYKVDDID 250
Query: 276 ----FEVTREAMLHLGIDTPTQNNIFKVLAGLLHLGNIQFAASEDEAQPCQPMDDAKYSV 331
F+ T AM +GI Q + +++AG+LHLGNI F + A +++ +
Sbjct: 251 DRREFQETLHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEVGNYAAV-----ESEEFL 305
Query: 332 RTAASLLGLPEDVLLEMVQIRTIRA---GRQQQVFRKPCARAECDTRRDCLAKLIYARLF 388
A LLG+ +D L E + R + + G+ + + C T RD LAK ++AR+F
Sbjct: 306 AFPAYLLGINQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYT-RDALAKALHARVF 364
Query: 389 DWLVSVINSSICADTDSWTTFIGLLDVYGFESFPDNSLEQLCINYANEKLQ 439
D+LV IN ++ D + + IG+LD+YGFE F N EQ CIN+ NEKLQ
Sbjct: 365 DFLVDSINKAMEKDHEEYN--IGVLDIYGFEIFQKNGFEQFCINFVNEKLQ 413
Score = 40.4 bits (93), Expect = 0.006
Identities = 44/150 (29%), Positives = 61/150 (40%), Gaps = 35/150 (23%)
Query: 437 KLQLEACGLVETIHISAAGFPIRVSHRNFVERYKLLRRLHPCTSSGPDSPYPAKGLPEWC 496
K Q+E GL E I + AG+ R + F++RY +L + P W
Sbjct: 604 KHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTK---------------ATWPSW- 647
Query: 497 PHSEEATLEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHCGRTKVFM-TDSMLELLEC 555
EE Q +LH L Q+ + D GR+KVF+ L LLE
Sbjct: 648 -QGEEK------QGVLH----LLQSVNMDSDQ-------FQLGRSKVFIKAPESLFLLEE 689
Query: 556 GRARVLEQCARCIQGGWRRHRHREQERQWR 585
R R + AR IQ WR+ R++ Q R
Sbjct: 690 MRERKYDGYARVIQKSWRKFVARKKYVQMR 719
>gi|27544941 myosin IF [Homo sapiens]
Length = 1098
Score = 238 bits (608), Expect = 1e-62
Identities = 149/410 (36%), Positives = 232/410 (56%), Gaps = 24/410 (5%)
Query: 37 LDDLTRVNPVTLETVLRCLQARYMADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHAA 96
+DD+ + +T + + L+ R+M D +T G L+++NPFK +P E+ Y A
Sbjct: 19 VDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDL-YQGA 77
Query: 97 PQPQKLKPHVFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATSP 156
Q + PH++ + + YRN+ LI+ NQ +++SGESGAGKT ++ +M + + V
Sbjct: 78 AQYEN-PPHIYALTDNMYRNM--LIDCENQCVIISGESGAGKTVAAKYIMGYISKV---- 130
Query: 157 ASWESHKIAERIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQ 216
S K+ + ++ IL SNP++EAFGNA T+RNNNSSRFGK+ ++Q +R + G +
Sbjct: 131 -SGGGEKV-QHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKIS 188
Query: 217 TYLLEKTRVACQASSERNFHIFYQICKGASEDERLQWHLPEGAAFSWLPNPER-----SL 271
+LLEK+RV Q +ERNFHI+YQ+ +GAS+++R L + +L + +
Sbjct: 189 NFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSDTYQVDGTD 248
Query: 272 EEDCFEVTREAMLHLGIDTPTQNNIFKVLAGLLHLGNIQFAASEDEAQPCQPMDDAKYSV 331
+ F T AM +GI Q + +++AG+LHLGNI F + A+ + +D +
Sbjct: 249 DRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYAR-VESVDLLAF-- 305
Query: 332 RTAASLLGLPEDVLLEMVQIRTI--RAGRQQQVFRKPCARAECDTRRDCLAKLIYARLFD 389
A LLG+ L E + R + R G + + + RD LAK +YARLFD
Sbjct: 306 --PAYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFD 363
Query: 390 WLVSVINSSICADTDSWTTFIGLLDVYGFESFPDNSLEQLCINYANEKLQ 439
+LV IN ++ + ++ IG+LD+YGFE F N EQ CIN+ NEKLQ
Sbjct: 364 FLVEAINRAMQKPQEEYS--IGVLDIYGFEIFQKNGFEQFCINFVNEKLQ 411
Score = 41.6 bits (96), Expect = 0.003
Identities = 46/158 (29%), Positives = 64/158 (40%), Gaps = 38/158 (24%)
Query: 437 KLQLEACGLVETIHISAAGFPIRVSHRNFVERYKLLRRLHPCTSSGPDSPYPAKGLPEWC 496
K Q+E GL E I + AGF R F++RY +L P++ P W
Sbjct: 602 KHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILT---------PET------WPRW- 645
Query: 497 PHSEEATLEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHCGRTKVFMTD-SMLELLEC 555
+E Q + H L + P G TKVF+ + L LLE
Sbjct: 646 -RGDER------QGVQHLLRAVNME-----------PDQYQMGSTKVFVKNPESLFLLEE 687
Query: 556 GRARVLEQCARCIQGGWRRH---RHREQERQWRAVMLI 590
R R + AR IQ WRRH R E+ R+ + +L+
Sbjct: 688 VRERKFDGFARTIQKAWRRHVAVRKYEEMREEASNILL 725
>gi|124494238 myosin IC isoform a [Homo sapiens]
Length = 1063
Score = 238 bits (606), Expect = 2e-62
Identities = 158/455 (34%), Positives = 246/455 (54%), Gaps = 37/455 (8%)
Query: 1 MLQQVNGHNP-----GSDGQAREYLREDLQEFLGGEVLLYKLDDLTRVNPVTLETVLRCL 55
+++ V+ H P GSDG +R ++ L + D + N + + L
Sbjct: 13 IIRVVHPHRPCKLALGSDG-----VRVTMESALTARDRVGVQDFVLLENFTSEAAFIENL 67
Query: 56 QARYMADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHAAPQPQKLKPHVFTVGEQTYR 115
+ R+ + YT G LV++NP++ + Q+YS + M Y ++ PH+F V + YR
Sbjct: 68 RRRFRENLIYTYIGPVLVSVNPYRDL-QIYSRQHMERYRGVSF-YEVPPHLFAVADTVYR 125
Query: 116 NVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATSPASWESHKIAERIEQRILNS 175
+++ E +Q++++SGESGAGKT ++ L++FYA +P + + R+L S
Sbjct: 126 ALRT--ERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPERGGA------VRDRLLQS 177
Query: 176 NPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQTYLLEKTRVACQASSERNF 235
NPV+EAFGNA TLRN+NSSRFGK++ +Q + G + +YLLEK+RV Q ERNF
Sbjct: 178 NPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSRVVHQNHGERNF 237
Query: 236 HIFYQICKGASEDERLQWHLPEG-AAFSWLPNPERSL-----EEDCFEVTREAMLHLGID 289
HIFYQ+ +G E+ + L ++ +L + + ++ ++V R+A+ +
Sbjct: 238 HIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKVVRKALTVIDFT 297
Query: 290 TPTQNNIFKVLAGLLHLGNIQFAASEDEAQPCQPMDDAKYSVRTAASLLGLPEDVLLEMV 349
++ ++A +LHLGNI FAA+E+ + KY R LL + L E +
Sbjct: 298 EDEVEDLLSIVASVLHLGNIHFAANEESNAQVTTENQLKYLTR----LLSVEGSTLREAL 353
Query: 350 QIRTIRAGRQQQVFRKPCARAECDTRRDCLAKLIYARLFDWLVSVINSSICA---DTDSW 406
R I A ++ + P + RD LAK +Y+R F WLV IN S+ + ++ SW
Sbjct: 354 THRKIIAKGEELL--SPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSLASKDVESPSW 411
Query: 407 --TTFIGLLDVYGFESFPDNSLEQLCINYANEKLQ 439
TT +GLLD+YGFE F NS EQ CINY NEKLQ
Sbjct: 412 RSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQ 446
Score = 34.7 bits (78), Expect = 0.34
Identities = 45/196 (22%), Positives = 73/196 (37%), Gaps = 50/196 (25%)
Query: 439 QLEACGLVETIHISAAGFPIRVSHRNFVERYKLLRRLHPCTSSGPDSPYPAKGLPEWCPH 498
Q++ GL+E + + AGF R + F++RYK L C + P W
Sbjct: 645 QVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSL-----CPET----------WPTWAGR 689
Query: 499 SEEATLEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHCGRTKVFM--------TDSML 550
++ A+ P GRTK+F+ T+ L
Sbjct: 690 PQD-------------------GVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDAL 730
Query: 551 ELLECGRARVLEQCARCIQGGWRRHRHREQ-ERQWRAVMLIQAAIRSWLTRKHIQRLHAA 609
E+ + A IQ WR R++ R R+ + IQ+ R L R+ + A
Sbjct: 731 EVRR-------QSLATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKWA 783
Query: 610 ATVIKRAWQKWRIRMA 625
A I+R + + +R A
Sbjct: 784 AQTIRRLIRGFVLRHA 799
>gi|124494247 myosin IC isoform b [Homo sapiens]
Length = 1044
Score = 237 bits (604), Expect = 3e-62
Identities = 147/396 (37%), Positives = 224/396 (56%), Gaps = 27/396 (6%)
Query: 55 LQARYMADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHAAPQPQKLKPHVFTVGEQTY 114
L+ R+ + YT G LV++NP++ + Q+YS + M Y ++ PH+F V + Y
Sbjct: 48 LRRRFRENLIYTYIGPVLVSVNPYRDL-QIYSRQHMERYRGVSF-YEVPPHLFAVADTVY 105
Query: 115 RNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATSPASWESHKIAERIEQRILN 174
R +++ E +Q++++SGESGAGKT ++ L++FYA +P + + R+L
Sbjct: 106 RALRT--ERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPERGGA------VRDRLLQ 157
Query: 175 SNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQTYLLEKTRVACQASSERN 234
SNPV+EAFGNA TLRN+NSSRFGK++ +Q + G + +YLLEK+RV Q ERN
Sbjct: 158 SNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSRVVHQNHGERN 217
Query: 235 FHIFYQICKGASEDERLQWHLPEG-AAFSWLPNPERSL-----EEDCFEVTREAMLHLGI 288
FHIFYQ+ +G E+ + L ++ +L + + ++ ++V R+A+ +
Sbjct: 218 FHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKVVRKALTVIDF 277
Query: 289 DTPTQNNIFKVLAGLLHLGNIQFAASEDEAQPCQPMDDAKYSVRTAASLLGLPEDVLLEM 348
++ ++A +LHLGNI FAA+E+ + KY R LL + L E
Sbjct: 278 TEDEVEDLLSIVASVLHLGNIHFAANEESNAQVTTENQLKYLTR----LLSVEGSTLREA 333
Query: 349 VQIRTIRAGRQQQVFRKPCARAECDTRRDCLAKLIYARLFDWLVSVINSSICA---DTDS 405
+ R I A ++ + P + RD LAK +Y+R F WLV IN S+ + ++ S
Sbjct: 334 LTHRKIIAKGEELL--SPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSLASKDVESPS 391
Query: 406 W--TTFIGLLDVYGFESFPDNSLEQLCINYANEKLQ 439
W TT +GLLD+YGFE F NS EQ CINY NEKLQ
Sbjct: 392 WRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQ 427
Score = 34.7 bits (78), Expect = 0.34
Identities = 45/196 (22%), Positives = 73/196 (37%), Gaps = 50/196 (25%)
Query: 439 QLEACGLVETIHISAAGFPIRVSHRNFVERYKLLRRLHPCTSSGPDSPYPAKGLPEWCPH 498
Q++ GL+E + + AGF R + F++RYK L C + P W
Sbjct: 626 QVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSL-----CPET----------WPTWAGR 670
Query: 499 SEEATLEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHCGRTKVFM--------TDSML 550
++ A+ P GRTK+F+ T+ L
Sbjct: 671 PQD-------------------GVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDAL 711
Query: 551 ELLECGRARVLEQCARCIQGGWRRHRHREQ-ERQWRAVMLIQAAIRSWLTRKHIQRLHAA 609
E+ + A IQ WR R++ R R+ + IQ+ R L R+ + A
Sbjct: 712 EVRR-------QSLATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKWA 764
Query: 610 ATVIKRAWQKWRIRMA 625
A I+R + + +R A
Sbjct: 765 AQTIRRLIRGFVLRHA 780
>gi|124494240 myosin IC isoform c [Homo sapiens]
Length = 1028
Score = 237 bits (604), Expect = 3e-62
Identities = 147/396 (37%), Positives = 224/396 (56%), Gaps = 27/396 (6%)
Query: 55 LQARYMADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHAAPQPQKLKPHVFTVGEQTY 114
L+ R+ + YT G LV++NP++ + Q+YS + M Y ++ PH+F V + Y
Sbjct: 32 LRRRFRENLIYTYIGPVLVSVNPYRDL-QIYSRQHMERYRGVSF-YEVPPHLFAVADTVY 89
Query: 115 RNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATSPASWESHKIAERIEQRILN 174
R +++ E +Q++++SGESGAGKT ++ L++FYA +P + + R+L
Sbjct: 90 RALRT--ERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPERGGA------VRDRLLQ 141
Query: 175 SNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQTYLLEKTRVACQASSERN 234
SNPV+EAFGNA TLRN+NSSRFGK++ +Q + G + +YLLEK+RV Q ERN
Sbjct: 142 SNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSRVVHQNHGERN 201
Query: 235 FHIFYQICKGASEDERLQWHLPEG-AAFSWLPNPERSL-----EEDCFEVTREAMLHLGI 288
FHIFYQ+ +G E+ + L ++ +L + + ++ ++V R+A+ +
Sbjct: 202 FHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKVVRKALTVIDF 261
Query: 289 DTPTQNNIFKVLAGLLHLGNIQFAASEDEAQPCQPMDDAKYSVRTAASLLGLPEDVLLEM 348
++ ++A +LHLGNI FAA+E+ + KY R LL + L E
Sbjct: 262 TEDEVEDLLSIVASVLHLGNIHFAANEESNAQVTTENQLKYLTR----LLSVEGSTLREA 317
Query: 349 VQIRTIRAGRQQQVFRKPCARAECDTRRDCLAKLIYARLFDWLVSVINSSICA---DTDS 405
+ R I A ++ + P + RD LAK +Y+R F WLV IN S+ + ++ S
Sbjct: 318 LTHRKIIAKGEELL--SPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSLASKDVESPS 375
Query: 406 W--TTFIGLLDVYGFESFPDNSLEQLCINYANEKLQ 439
W TT +GLLD+YGFE F NS EQ CINY NEKLQ
Sbjct: 376 WRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQ 411
Score = 34.7 bits (78), Expect = 0.34
Identities = 45/196 (22%), Positives = 73/196 (37%), Gaps = 50/196 (25%)
Query: 439 QLEACGLVETIHISAAGFPIRVSHRNFVERYKLLRRLHPCTSSGPDSPYPAKGLPEWCPH 498
Q++ GL+E + + AGF R + F++RYK L C + P W
Sbjct: 610 QVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSL-----CPET----------WPTWAGR 654
Query: 499 SEEATLEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHCGRTKVFM--------TDSML 550
++ A+ P GRTK+F+ T+ L
Sbjct: 655 PQD-------------------GVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDAL 695
Query: 551 ELLECGRARVLEQCARCIQGGWRRHRHREQ-ERQWRAVMLIQAAIRSWLTRKHIQRLHAA 609
E+ + A IQ WR R++ R R+ + IQ+ R L R+ + A
Sbjct: 696 EVRR-------QSLATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKWA 748
Query: 610 ATVIKRAWQKWRIRMA 625
A I+R + + +R A
Sbjct: 749 AQTIRRLIRGFVLRHA 764
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 235 bits (599), Expect = 1e-61
Identities = 142/407 (34%), Positives = 227/407 (55%), Gaps = 12/407 (2%)
Query: 36 KLDDLTRVNPVTLETVLRCLQARYMADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHA 95
K +D+ + + +VL L+ RY + YT +G V +NP+K +P +Y+ ++ Y
Sbjct: 106 KAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLP-IYTEAIVEMYRG 164
Query: 96 APQPQKLKPHVFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATS 155
+ ++ PHV+ V E YR++ L + +QSI+ +GESGAGKT ++ ++++ A VA+S
Sbjct: 165 KKR-HEVPPHVYAVTEGAYRSM--LQDREDQSILCTGESGAGKTENTKKVIQYLAHVASS 221
Query: 156 PASWESHKIAERIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAV 215
P + + +E+++L +NP++EAFGNA T++N+NSSRFGKFI++ + A + GA +
Sbjct: 222 PKGRKEPGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANI 281
Query: 216 QTYLLEKTRVACQASSERNFHIFYQICKGASEDERLQWHLPEGAAFSWL---PNPERSLE 272
+TYLLEK+R QA E +FHIFYQ+ GA E + L + + +L P+ E
Sbjct: 282 ETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQE 341
Query: 273 EDCFEVTREAMLHLGIDTPTQNNIFKVLAGLLHLGNIQFAASEDEAQPCQPMDDAKYSVR 332
+ F+ T E++ LG ++ ++++ +L GNI + Q P + A +
Sbjct: 342 RELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTA---AQ 398
Query: 333 TAASLLGLPEDVLLEMVQIRTIRAGRQQQVFRKPCARAECDTRRDCLAKLIYARLFDWLV 392
LLGL + I+ GR +K + + D + LAK Y RLF WLV
Sbjct: 399 KLCRLLGLGVTDFSRALLTPRIKVGR--DYVQKAQTKEQADFALEALAKATYERLFRWLV 456
Query: 393 SVINSSICADTDSWTTFIGLLDVYGFESFPDNSLEQLCINYANEKLQ 439
+N ++ +F+G+LD+ GFE F NS EQLCINY NEKLQ
Sbjct: 457 LRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQ 503
Score = 32.7 bits (73), Expect = 1.3
Identities = 44/186 (23%), Positives = 72/186 (38%), Gaps = 48/186 (25%)
Query: 439 QLEACGLVETIHISAAGFPIRVSHRNFVERYKLLRRLHPCTSSGPDSPYPAKGLPEWCPH 498
QL G++E I I GFP R+ + F +RY++L +P+
Sbjct: 715 QLRCNGVLEGIRICRQGFPNRILFQEFRQRYEIL---------------TPNAIPKGFMD 759
Query: 499 SEEATLEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHCGRTKVFMTDSMLELLECGRA 558
++A E +IQ + E P G++K+F +L LE R
Sbjct: 760 GKQA-CEKMIQ------------------ALELDPNLYRVGQSKIFFRAGVLAQLEEERD 800
Query: 559 RVLEQCARCIQGGWRRH--RHREQERQWRAVMLIQAAIRSWLTRKHIQRLHAAATVIKRA 616
+ Q R + R Q+RQ + Q+A+R + + + AA + R
Sbjct: 801 LKVTDIIVSFQAAARGYLARRAFQKRQQQ-----QSALR-------VMQRNCAAYLKLRH 848
Query: 617 WQKWRI 622
WQ WR+
Sbjct: 849 WQWWRL 854
>gi|118402590 myosin XV [Homo sapiens]
Length = 3530
Score = 231 bits (590), Expect = 1e-60
Identities = 143/408 (35%), Positives = 234/408 (57%), Gaps = 23/408 (5%)
Query: 37 LDDLTRVNPVTLETVLRCLQARYMADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHAA 96
++D+T++ + TVL L+ R+ + YT G LV++NP++ +Y PE +++Y+
Sbjct: 1224 VEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFG-IYGPEQVQQYNGR 1282
Query: 97 PQPQKLKPHVFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATSP 156
+ PH+F V + K L NQ I++SGESG+GKT ++ ++++ A +
Sbjct: 1283 ALGEN-PPHLFAVANLAF--AKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMN--- 1336
Query: 157 ASWESHKIAERIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQ 216
+ ++ ++I +IL + P++E+FGNA T+RN+NSSRFGKF+++ L ++GA
Sbjct: 1337 ---QKREVMQQI--KILEATPLLESFGNAKTVRNDNSSRFGKFVEIFLEGGV-ISGAITS 1390
Query: 217 TYLLEKTRVACQASSERNFHIFYQICKGASEDERLQWHLPEGAAFSWLP---NPERSLEE 273
YLLEK+R+ QA +ERN+HIFY++ G R + L E + +L N E + +
Sbjct: 1391 QYLLEKSRIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKS 1450
Query: 274 DCFEVTR--EAMLHLGIDTPTQNNIFKVLAGLLHLGNIQFAASEDEAQPCQPMDDAKYSV 331
D + R AM LG + Q++IF++LA +LHLGN+ F E +AQ + A+ +
Sbjct: 1451 DADDFRRLLAAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAR-EI 1509
Query: 332 RTAASLLGLPEDVLLEMVQIRTIRAGRQQQVFRKPCARAECDTRRDCLAKLIYARLFDWL 391
+ A LL + + L + + + R++ +F + D R D +AK++YA LF WL
Sbjct: 1510 QAVAELLQISPEGLQKAITFKVTETMREK-IFTPLTVESAVDAR-DAIAKVLYALLFSWL 1567
Query: 392 VSVINSSICADTDSWTTFIGLLDVYGFESFPDNSLEQLCINYANEKLQ 439
++ +N+ + D T I +LD+YGFE NS EQLCINYANE LQ
Sbjct: 1568 ITRVNALVSPRQD--TLSIAILDIYGFEDLSFNSFEQLCINYANENLQ 1613
Score = 52.8 bits (125), Expect = 1e-06
Identities = 46/201 (22%), Positives = 79/201 (39%), Gaps = 51/201 (25%)
Query: 439 QLEACGLVETIHISAAGFPIRVSHRNFVERYKLLRRLHPCTSSGPDSPYPAKGLPEWCPH 498
QL G++ET+ I GFP+R+ + F++RY C PA G
Sbjct: 1815 QLRYSGVLETVRIRKEGFPVRLPFQGFIDRY--------CCLVALKHDLPANG------- 1859
Query: 499 SEEATLEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHCGRTKVFMTDSMLELLECGRA 558
++ + MP G +K+F+ + + +LLE R
Sbjct: 1860 --------------------DMCVSVLSRLCKVMPNMYRVGVSKLFLKEHLYQLLESMRE 1899
Query: 559 RVLEQCA----RCIQGGWRRHRHREQERQWRAVMLIQAAIRSWLTRKHIQRLHAA----- 609
VL A RC++G + + R R + ++L+Q+ R +L R+ Q++ +
Sbjct: 1900 HVLNLAALTLQRCLRGFFIKRRFRSLRHK---IILLQSRARGYLARQRYQQMRRSLVKFR 1956
Query: 610 ----ATVIKRAWQKWRIRMAC 626
A V +R + K R C
Sbjct: 1957 SLVHAYVSRRRYLKLRAEWRC 1977
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.134 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,542,513
Number of Sequences: 37866
Number of extensions: 1410279
Number of successful extensions: 3765
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 61
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 3292
Number of HSP's gapped (non-prelim): 211
length of query: 770
length of database: 18,247,518
effective HSP length: 110
effective length of query: 660
effective length of database: 14,082,258
effective search space: 9294290280
effective search space used: 9294290280
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.