Guide to the Human Genome
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Search of human proteins with 19923599

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19923599 calmin [Homo sapiens]
         (1002 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19923599 calmin [Homo sapiens]                                    1988   0.0  
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof...   265   1e-70
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo...   259   7e-69
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof...   224   4e-58
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof...   224   4e-58
gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo ...   180   7e-45
gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo ...   179   9e-45
gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens]          176   1e-43
gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [...   176   1e-43
gi|67782321 spectrin beta isoform a [Homo sapiens]                    175   2e-43
gi|67782319 spectrin beta isoform b [Homo sapiens]                    175   2e-43
gi|41322908 plectin 1 isoform 3 [Homo sapiens]                        170   5e-42
gi|41322919 plectin 1 isoform 8 [Homo sapiens]                        170   7e-42
gi|41322912 plectin 1 isoform 2 [Homo sapiens]                        168   2e-41
gi|41322923 plectin 1 isoform 11 [Homo sapiens]                       168   3e-41
gi|41322914 plectin 1 isoform 10 [Homo sapiens]                       168   3e-41
gi|41322910 plectin 1 isoform 7 [Homo sapiens]                        168   3e-41
gi|41322916 plectin 1 isoform 6 [Homo sapiens]                        168   3e-41
gi|47607492 plectin 1 isoform 1 [Homo sapiens]                        168   3e-41
gi|33188445 microfilament and actin filament cross-linker protei...   167   6e-41
gi|34577047 dystonin isoform 1 [Homo sapiens]                         166   8e-41
gi|110611228 utrophin [Homo sapiens]                                  165   2e-40
gi|169218211 PREDICTED: similar to plectin 1, partial [Homo sapi...   165   2e-40
gi|221316624 dystonin isoform 4 [Homo sapiens]                        165   2e-40
gi|221316622 dystonin isoform 3 [Homo sapiens]                        165   2e-40
gi|221316618 dystonin isoform 2 [Homo sapiens]                        165   2e-40
gi|5032281 dystrophin Dp427c isoform [Homo sapiens]                   162   2e-39
gi|5032287 dystrophin Dp427p1 isoform [Homo sapiens]                  161   3e-39
gi|5032283 dystrophin Dp427m isoform [Homo sapiens]                   161   3e-39
gi|12025678 actinin, alpha 4 [Homo sapiens]                           150   4e-36

>gi|19923599 calmin [Homo sapiens]
          Length = 1002

 Score = 1988 bits (5151), Expect = 0.0
 Identities = 1002/1002 (100%), Positives = 1002/1002 (100%)

Query: 1    MAAHEWDWFQREELIGQISDIRVQNLQVERENVQKRTFTRWINLHLEKCNPPLEVKDLFV 60
            MAAHEWDWFQREELIGQISDIRVQNLQVERENVQKRTFTRWINLHLEKCNPPLEVKDLFV
Sbjct: 1    MAAHEWDWFQREELIGQISDIRVQNLQVERENVQKRTFTRWINLHLEKCNPPLEVKDLFV 60

Query: 61   DIQDGKILMALLEVLSGRNLLHEYKSSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIA 120
            DIQDGKILMALLEVLSGRNLLHEYKSSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIA
Sbjct: 61   DIQDGKILMALLEVLSGRNLLHEYKSSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIA 120

Query: 121  DGNPSLVLGLIWNIILFFQIKELTGNLSRNSPSSSLSPGSGGTDSDSSFPPTPTAERSVA 180
            DGNPSLVLGLIWNIILFFQIKELTGNLSRNSPSSSLSPGSGGTDSDSSFPPTPTAERSVA
Sbjct: 121  DGNPSLVLGLIWNIILFFQIKELTGNLSRNSPSSSLSPGSGGTDSDSSFPPTPTAERSVA 180

Query: 181  ISVKDQRKAIKALLAWVQRKTRKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALE 240
            ISVKDQRKAIKALLAWVQRKTRKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALE
Sbjct: 181  ISVKDQRKAIKALLAWVQRKTRKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALE 240

Query: 241  NSTRENLEKAFSIAQDALHIPRLLEPEDIMVDTPDEQSIMTYVAQFLERFPELEAEDIFD 300
            NSTRENLEKAFSIAQDALHIPRLLEPEDIMVDTPDEQSIMTYVAQFLERFPELEAEDIFD
Sbjct: 241  NSTRENLEKAFSIAQDALHIPRLLEPEDIMVDTPDEQSIMTYVAQFLERFPELEAEDIFD 300

Query: 301  SDKEVPIESTFVRIKETPSEQESKVFVLTENGERTYTVNHETSHPPPSKVFVCDKPESMK 360
            SDKEVPIESTFVRIKETPSEQESKVFVLTENGERTYTVNHETSHPPPSKVFVCDKPESMK
Sbjct: 301  SDKEVPIESTFVRIKETPSEQESKVFVLTENGERTYTVNHETSHPPPSKVFVCDKPESMK 360

Query: 361  EFRLDGVSSHALSDSSTEFMHQIIDQVLQGGPGKTSDISEPSPESSILSSRKENGRSNSL 420
            EFRLDGVSSHALSDSSTEFMHQIIDQVLQGGPGKTSDISEPSPESSILSSRKENGRSNSL
Sbjct: 361  EFRLDGVSSHALSDSSTEFMHQIIDQVLQGGPGKTSDISEPSPESSILSSRKENGRSNSL 420

Query: 421  PIKKTVHFEADTYKDPFCSKNLSLCFEGSPRVAKESLRQDGHVLAVEVAEEKEQKQESSK 480
            PIKKTVHFEADTYKDPFCSKNLSLCFEGSPRVAKESLRQDGHVLAVEVAEEKEQKQESSK
Sbjct: 421  PIKKTVHFEADTYKDPFCSKNLSLCFEGSPRVAKESLRQDGHVLAVEVAEEKEQKQESSK 480

Query: 481  IPESSSDKVAGDIFLVEGTNNNSQSSSCNGALESTARHDEESHSLSPPGENTVMADSFQI 540
            IPESSSDKVAGDIFLVEGTNNNSQSSSCNGALESTARHDEESHSLSPPGENTVMADSFQI
Sbjct: 481  IPESSSDKVAGDIFLVEGTNNNSQSSSCNGALESTARHDEESHSLSPPGENTVMADSFQI 540

Query: 541  KVNLMTVEALEEGDYFEAIPLKASKFNSDLIDFASTSQAFNKVPSPHETKPDEDAEAFEN 600
            KVNLMTVEALEEGDYFEAIPLKASKFNSDLIDFASTSQAFNKVPSPHETKPDEDAEAFEN
Sbjct: 541  KVNLMTVEALEEGDYFEAIPLKASKFNSDLIDFASTSQAFNKVPSPHETKPDEDAEAFEN 600

Query: 601  HAEKLGKRSIKSAHKKKDSPEPQVKMDKHEPHQDSGEEAEGCPSAPEETPVDKKPEVHEK 660
            HAEKLGKRSIKSAHKKKDSPEPQVKMDKHEPHQDSGEEAEGCPSAPEETPVDKKPEVHEK
Sbjct: 601  HAEKLGKRSIKSAHKKKDSPEPQVKMDKHEPHQDSGEEAEGCPSAPEETPVDKKPEVHEK 660

Query: 661  AKRKSTRPHYEEEGEDDDLQGVGEELSSSPPSSCVSLETLGSHSEEGLDFKPSPPLSKVS 720
            AKRKSTRPHYEEEGEDDDLQGVGEELSSSPPSSCVSLETLGSHSEEGLDFKPSPPLSKVS
Sbjct: 661  AKRKSTRPHYEEEGEDDDLQGVGEELSSSPPSSCVSLETLGSHSEEGLDFKPSPPLSKVS 720

Query: 721  VIPHDLFYFPHYEVPLAAVLEAYVEDPEDLKNEEMDLEEPEGYMPDLDSREEEADGSQSS 780
            VIPHDLFYFPHYEVPLAAVLEAYVEDPEDLKNEEMDLEEPEGYMPDLDSREEEADGSQSS
Sbjct: 721  VIPHDLFYFPHYEVPLAAVLEAYVEDPEDLKNEEMDLEEPEGYMPDLDSREEEADGSQSS 780

Query: 781  SSSSVPGESLPSASDQVLYLSRGGVGTTPASEPAPLAPHEDHQQRETKENDPMDSHQSQE 840
            SSSSVPGESLPSASDQVLYLSRGGVGTTPASEPAPLAPHEDHQQRETKENDPMDSHQSQE
Sbjct: 781  SSSSVPGESLPSASDQVLYLSRGGVGTTPASEPAPLAPHEDHQQRETKENDPMDSHQSQE 840

Query: 841  SPNLENIANPLEENVTKESISSKKKEKRKHVDHVESSLFVAPGSVQSSDDLEEDSSDYSI 900
            SPNLENIANPLEENVTKESISSKKKEKRKHVDHVESSLFVAPGSVQSSDDLEEDSSDYSI
Sbjct: 841  SPNLENIANPLEENVTKESISSKKKEKRKHVDHVESSLFVAPGSVQSSDDLEEDSSDYSI 900

Query: 901  PSRTSHSDSSIYLRRHTHRSSESDHFSYVQLRNAADLDDRRNRILTRKANSSGEAMSLGS 960
            PSRTSHSDSSIYLRRHTHRSSESDHFSYVQLRNAADLDDRRNRILTRKANSSGEAMSLGS
Sbjct: 901  PSRTSHSDSSIYLRRHTHRSSESDHFSYVQLRNAADLDDRRNRILTRKANSSGEAMSLGS 960

Query: 961  HSPQSDSLTQLVQQPDMMYFILFLWLLVYCLLLFPQLDVSRL 1002
            HSPQSDSLTQLVQQPDMMYFILFLWLLVYCLLLFPQLDVSRL
Sbjct: 961  HSPQSDSLTQLVQQPDMMYFILFLWLLVYCLLLFPQLDVSRL 1002


>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform
           1 [Homo sapiens]
          Length = 8797

 Score =  265 bits (678), Expect = 1e-70
 Identities = 166/350 (47%), Positives = 218/350 (62%), Gaps = 19/350 (5%)

Query: 23  VQNLQVERENVQKRTFTRWINLHLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLH 82
           +Q LQ E+E VQKRTFT+WIN HL K  PP+ V DLF D++DG  L+ALLEVLSG+ L  
Sbjct: 18  MQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGVKLLALLEVLSGQKLPC 77

Query: 83  EYKSSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFFQIKE 142
           E      RI  + NI  ALKFLE   +KLV+I++ +IADG PS+VLGL+W IIL+FQI+E
Sbjct: 78  EQGRRMKRIHAVANIGTALKFLEGRKIKLVNINSTDIADGRPSIVLGLMWTIILYFQIEE 137

Query: 143 LTGNLSRNSPSSSLSPGSGGTDS-DSSFPPTPTAERSVAISVKDQRKAIKALLAWVQRKT 201
           LT NL +     SLS  +   DS  SS  P+P ++R V  + K Q  A KALL WVQ   
Sbjct: 138 LTSNLPQ---LQSLSSSASSVDSIVSSETPSPPSKRKV--TTKIQGNAKKALLKWVQYTA 192

Query: 202 RKY-GVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHI 260
            K  G+ V+DF  SWRSG+AF +VI AI P LVD++     S RENLE AF+IA+  L I
Sbjct: 193 GKQTGIEVKDFGKSWRSGVAFHSVIHAIRPELVDLETVKGRSNRENLEDAFTIAETELGI 252

Query: 261 PRLLEPEDIMVDTPDEQSIMTYVAQFLERFPELE--AEDIFDSDKEVPIESTFVRIKETP 318
           PRLL+PED+ VD PDE+SIMTYVAQFL+ +P++   + D  + D+ +P   +F    +  
Sbjct: 253 PRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDIHNASTDGQEDDEILPGFPSFANSVQNF 312

Query: 319 SEQESKVF----VLTENGERTYTVNHETSHPPPSKVFVCDKPESMKEFRL 364
             ++  +F    V  E  ER  T           +  + DK +S K FR+
Sbjct: 313 KREDRVIFKEMKVWIEQFERDLT------RAQMVESNLQDKYQSFKHFRV 356


>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform
           2 [Homo sapiens]
          Length = 8749

 Score =  259 bits (663), Expect = 7e-69
 Identities = 167/357 (46%), Positives = 219/357 (61%), Gaps = 26/357 (7%)

Query: 23  VQNLQVERENVQKRTFTRWINLHLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLH 82
           +Q LQ E+E VQKRTFT+WIN HL K  PP+ V DLF D++DG  L+ALLEVLSG+ L  
Sbjct: 18  MQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGVKLLALLEVLSGQKLPC 77

Query: 83  EYKSSSHRIFRLNNIAKALKFLED-------SNVKLVSIDAAEIADGNPSLVLGLIWNII 135
           E      RI  + NI  ALKFLE        S +KLV+I++ +IADG PS+VLGL+W II
Sbjct: 78  EQGRRMKRIHAVANIGTALKFLEGRKSMHRGSPIKLVNINSTDIADGRPSIVLGLMWTII 137

Query: 136 LFFQIKELTGNLSRNSPSSSLSPGSGGTDSD-SSFPPTPTAERSVAISVKDQRKAIKALL 194
           L+FQI+ELT NL +     SLS  +   DS  SS  P+P ++R V  + K Q  A KALL
Sbjct: 138 LYFQIEELTSNLPQ---LQSLSSSASSVDSIVSSETPSPPSKRKV--TTKIQGNAKKALL 192

Query: 195 AWVQRKTRKY-GVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSI 253
            WVQ    K  G+ V+DF  SWRSG+AF +VI AI P LVD++     S RENLE AF+I
Sbjct: 193 KWVQYTAGKQTGIEVKDFGKSWRSGVAFHSVIHAIRPELVDLETVKGRSNRENLEDAFTI 252

Query: 254 AQDALHIPRLLEPEDIMVDTPDEQSIMTYVAQFLERFPELE--AEDIFDSDKEVPIESTF 311
           A+  L IPRLL+PED+ VD PDE+SIMTYVAQFL+ +P++   + D  + D+ +P   +F
Sbjct: 253 AETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDIHNASTDGQEDDEILPGFPSF 312

Query: 312 VRIKETPSEQESKVF----VLTENGERTYTVNHETSHPPPSKVFVCDKPESMKEFRL 364
               +    ++  +F    V  E  ER  T           +  + DK +S K FR+
Sbjct: 313 ANSVQNFKREDRVIFKEMKVWIEQFERDLT------RAQMVESNLQDKYQSFKHFRV 363


>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform
           5 [Homo sapiens]
          Length = 6907

 Score =  224 bits (570), Expect = 4e-58
 Identities = 128/272 (47%), Positives = 173/272 (63%), Gaps = 7/272 (2%)

Query: 18  ISDIRVQNLQVERENVQKRTFTRWINLHLEKCNPPLEVKDLFVDIQDGKILMALLEVLSG 77
           I D+ + +LQ E+E+ QK+ FT WIN  L +   P  + DLF DI+ G +L+ LLEVLSG
Sbjct: 18  IDDLHI-SLQAEQEDTQKKAFTCWINSQLARHTSPSVISDLFTDIKKGHVLLDLLEVLSG 76

Query: 78  RNLLHEYKSSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILF 137
           + L  +  S++ +  R+N I  AL FL + ++KL++I   +I DGNPS++LGLIW IIL 
Sbjct: 77  QQLPRDKGSNTFQC-RIN-IEHALTFLRNRSIKLINIHVTDIIDGNPSIILGLIWTIILH 134

Query: 138 FQIKELTGNLSRNSPSSSLSPGSGGTDSDSSFPPTPTAERSVAISVKDQRKAIKALLAWV 197
           F I++L   LS N    SL   S    S +S PP   A++   +  + Q  A KALL W 
Sbjct: 135 FHIEKLAQTLSCNYNQPSLDDVSVVDSSPASSPP---AKKCSKVQARWQMSARKALLLWA 191

Query: 198 QRKTRKY-GVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQD 256
           Q +   Y  V V DF  SWR+G+AFLA+I A+ P L+DMK     S ++NL +AF IA+ 
Sbjct: 192 QEQCATYESVNVTDFKSSWRNGMAFLAIIHALRPDLIDMKSVKHRSNKDNLREAFRIAEQ 251

Query: 257 ALHIPRLLEPEDIMVDTPDEQSIMTYVAQFLE 288
            L IPRLLEPED+ V  PDE+SIMTYVAQFL+
Sbjct: 252 ELKIPRLLEPEDVDVVDPDEKSIMTYVAQFLQ 283


>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform
           1 [Homo sapiens]
          Length = 6885

 Score =  224 bits (570), Expect = 4e-58
 Identities = 128/272 (47%), Positives = 173/272 (63%), Gaps = 7/272 (2%)

Query: 18  ISDIRVQNLQVERENVQKRTFTRWINLHLEKCNPPLEVKDLFVDIQDGKILMALLEVLSG 77
           I D+ + +LQ E+E+ QK+ FT WIN  L +   P  + DLF DI+ G +L+ LLEVLSG
Sbjct: 18  IDDLHI-SLQAEQEDTQKKAFTCWINSQLARHTSPSVISDLFTDIKKGHVLLDLLEVLSG 76

Query: 78  RNLLHEYKSSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILF 137
           + L  +  S++ +  R+N I  AL FL + ++KL++I   +I DGNPS++LGLIW IIL 
Sbjct: 77  QQLPRDKGSNTFQC-RIN-IEHALTFLRNRSIKLINIHVTDIIDGNPSIILGLIWTIILH 134

Query: 138 FQIKELTGNLSRNSPSSSLSPGSGGTDSDSSFPPTPTAERSVAISVKDQRKAIKALLAWV 197
           F I++L   LS N    SL   S    S +S PP   A++   +  + Q  A KALL W 
Sbjct: 135 FHIEKLAQTLSCNYNQPSLDDVSVVDSSPASSPP---AKKCSKVQARWQMSARKALLLWA 191

Query: 198 QRKTRKY-GVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQD 256
           Q +   Y  V V DF  SWR+G+AFLA+I A+ P L+DMK     S ++NL +AF IA+ 
Sbjct: 192 QEQCATYESVNVTDFKSSWRNGMAFLAIIHALRPDLIDMKSVKHRSNKDNLREAFRIAEQ 251

Query: 257 ALHIPRLLEPEDIMVDTPDEQSIMTYVAQFLE 288
            L IPRLLEPED+ V  PDE+SIMTYVAQFL+
Sbjct: 252 ELKIPRLLEPEDVDVVDPDEKSIMTYVAQFLQ 283


>gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo
           sapiens]
          Length = 2155

 Score =  180 bits (456), Expect = 7e-45
 Identities = 106/275 (38%), Positives = 156/275 (56%), Gaps = 37/275 (13%)

Query: 22  RVQNLQVERENVQKRTFTRWINLHLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLL 81
           R + LQ ERE VQK+TFT+W+N HL + +    + DL+ D++DG++L+ LLEVLSG  L 
Sbjct: 31  RFKQLQDEREAVQKKTFTKWVNSHLARVS--CRITDLYTDLRDGRMLIKLLEVLSGERLP 88

Query: 82  HEYKSSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFFQIK 141
              K    RI  L N+ KAL+FL++  V L ++ + +I DGN  L LGLIW IIL FQI+
Sbjct: 89  KPTKGRM-RIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQ 147

Query: 142 ELTGNLSRNSPSSSLSPGSGGTDSDSSFPPTPTAERSVAISVKDQRKAIKALLAWVQRKT 201
           +++     N                                 K+++ A  ALL W Q KT
Sbjct: 148 DISVETEDN---------------------------------KEKKSAKDALLLWCQMKT 174

Query: 202 RKY-GVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHI 260
             Y  V + +F  SWR G+AF A+I    P L+D  +  +++   NL+ AF++A+  L +
Sbjct: 175 AGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGL 234

Query: 261 PRLLEPEDIMVDTPDEQSIMTYVAQFLERFPELEA 295
            +LL+PEDI VD PDE+SI+TYV  +   F +++A
Sbjct: 235 TKLLDPEDISVDHPDEKSIITYVVTYYHYFSKMKA 269


>gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo
           sapiens]
          Length = 2364

 Score =  179 bits (455), Expect = 9e-45
 Identities = 107/290 (36%), Positives = 158/290 (54%), Gaps = 37/290 (12%)

Query: 7   DWFQREELIGQISDIRVQNLQVERENVQKRTFTRWINLHLEKCNPPLEVKDLFVDIQDGK 66
           DW             R++ L  ERE VQK+TFT+W+N HL + +    + DL+ D++DG+
Sbjct: 29  DWDNENSSARLFERSRIKALADEREAVQKKTFTKWVNSHLARVS--CRITDLYTDLRDGR 86

Query: 67  ILMALLEVLSGRNLLHEYKSSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSL 126
           +L+ LLEVLSG  L    K    RI  L N+ KAL+FL++  V L ++ + +I DGN  L
Sbjct: 87  MLIKLLEVLSGERLPKPTKGRM-RIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRL 145

Query: 127 VLGLIWNIILFFQIKELTGNLSRNSPSSSLSPGSGGTDSDSSFPPTPTAERSVAISVKDQ 186
            LGLIW IIL FQI++++     N                                 K++
Sbjct: 146 TLGLIWTIILRFQIQDISVETEDN---------------------------------KEK 172

Query: 187 RKAIKALLAWVQRKTRKY-GVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRE 245
           + A  ALL W Q KT  Y  V + +F  SWR G+AF A+I    P L+D  +  +++   
Sbjct: 173 KSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHY 232

Query: 246 NLEKAFSIAQDALHIPRLLEPEDIMVDTPDEQSIMTYVAQFLERFPELEA 295
           NL+ AF++A+  L + +LL+PEDI VD PDE+SI+TYV  +   F +++A
Sbjct: 233 NLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSIITYVVTYYHYFSKMKA 282



 Score = 30.4 bits (67), Expect = 8.7
 Identities = 26/90 (28%), Positives = 39/90 (43%), Gaps = 14/90 (15%)

Query: 401  PSPESSILSSRKENGRSNSLPIKKTVHFEADTYKDPFCSKNLSLCFEGSPRVAKESLRQD 460
            PSPE S   S +   +            + DT K    S+N     +GSPR+A+     D
Sbjct: 2101 PSPEPSTKVSEEAESQQ-----------QWDTSKGEQVSQNGLPAEQGSPRMAETV---D 2146

Query: 461  GHVLAVEVAEEKEQKQESSKIPESSSDKVA 490
               +     E++   +ESS IP  +SD+ A
Sbjct: 2147 TSEMVNGATEQRTSSKESSPIPSPTSDRKA 2176


>gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens]
          Length = 2390

 Score =  176 bits (446), Expect = 1e-43
 Identities = 107/290 (36%), Positives = 157/290 (54%), Gaps = 37/290 (12%)

Query: 7   DWFQREELIGQISDIRVQNLQVERENVQKRTFTRWINLHLEKCNPPLEVKDLFVDIQDGK 66
           DW             R++ L  ERE VQK+TFT+W+N HL +      V DL+ D++DG+
Sbjct: 32  DWDNDSSSARLFERSRIKALADEREAVQKKTFTKWVNSHLARVT--CRVGDLYSDLRDGR 89

Query: 67  ILMALLEVLSGRNLLHEYKSSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSL 126
            L+ LLEVLSG  +L +      RI  L N+ KAL+FL++  V L ++ + +I DGN  L
Sbjct: 90  NLLRLLEVLSGE-ILPKPTKGRMRIHCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRL 148

Query: 127 VLGLIWNIILFFQIKELTGNLSRNSPSSSLSPGSGGTDSDSSFPPTPTAERSVAISVKDQ 186
            LGL+W IIL FQI++++     N                                 K++
Sbjct: 149 TLGLVWTIILRFQIQDISVETEDN---------------------------------KEK 175

Query: 187 RKAIKALLAWVQRKTRKY-GVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRE 245
           + A  ALL W Q KT  Y  V V +F  SWR GLAF A++    P L+D +   + +   
Sbjct: 176 KSAKDALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHY 235

Query: 246 NLEKAFSIAQDALHIPRLLEPEDIMVDTPDEQSIMTYVAQFLERFPELEA 295
           NL+ AF++A+  L + +LL+PED+ VD PDE+SI+TYVA +   F +++A
Sbjct: 236 NLQNAFNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKA 285


>gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1
           [Homo sapiens]
          Length = 2564

 Score =  176 bits (446), Expect = 1e-43
 Identities = 106/275 (38%), Positives = 151/275 (54%), Gaps = 37/275 (13%)

Query: 22  RVQNLQVERENVQKRTFTRWINLHLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLL 81
           R++ L  ERE VQK+TFT+W+N HL +      + DL+VD++DG +L  LLEVLSG  L 
Sbjct: 51  RIKALADEREAVQKKTFTKWVNSHLARVG--CHIGDLYVDLRDGFVLTRLLEVLSGEQLP 108

Query: 82  HEYKSSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFFQIK 141
              +    RI  L N+ KAL+FL++  V L ++ + +I DGN  L LGL+W IIL FQI+
Sbjct: 109 RPTRGRM-RIHSLENVDKALQFLKEQRVHLENVGSHDIVDGNHRLTLGLVWTIILRFQIQ 167

Query: 142 ELTGNLSRNSPSSSLSPGSGGTDSDSSFPPTPTAERSVAISVKDQRKAIKALLAWVQRKT 201
            +      N                                 ++ R A  ALL W Q KT
Sbjct: 168 VIKIETEDN---------------------------------RETRSAKDALLLWCQMKT 194

Query: 202 RKY-GVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHI 260
             Y  V +Q+F  SWR GLAF A+I    P LVD  +  +++   NL++AF  A+  L +
Sbjct: 195 AGYPEVNIQNFTTSWRDGLAFNALIHRHRPDLVDFSKLTKSNANYNLQRAFRTAEQHLGL 254

Query: 261 PRLLEPEDIMVDTPDEQSIMTYVAQFLERFPELEA 295
            RLL+PED+ ++ PDE+SI+TYV  F   F +++A
Sbjct: 255 ARLLDPEDVNMEAPDEKSIITYVVSFYHYFSKMKA 289


>gi|67782321 spectrin beta isoform a [Homo sapiens]
          Length = 2328

 Score =  175 bits (443), Expect = 2e-43
 Identities = 106/274 (38%), Positives = 152/274 (55%), Gaps = 37/274 (13%)

Query: 22  RVQNLQVERENVQKRTFTRWINLHLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLL 81
           R++ L  ERE VQK+TFT+W+N HL + +    + DL+ D++DG++L+ LLEVLSG  L 
Sbjct: 44  RIKALADEREVVQKKTFTKWVNSHLARVS--CRITDLYKDLRDGRMLIKLLEVLSGEMLP 101

Query: 82  HEYKSSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFFQIK 141
              K    RI  L N+ KAL+FL++  V L ++ + +I DGN  LVLGLIW IIL FQI+
Sbjct: 102 KPTKGKM-RIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQ 160

Query: 142 ELTGNLSRNSPSSSLSPGSGGTDSDSSFPPTPTAERSVAISVKDQRKAIKALLAWVQRKT 201
           ++                                        ++ R A  ALL W Q KT
Sbjct: 161 DIVVQTQEG---------------------------------RETRSAKDALLLWCQMKT 187

Query: 202 RKY-GVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHI 260
             Y  V V +F  SW+ GLAF A+I    P L+D  +  +++ R NLE AF++A+  L I
Sbjct: 188 AGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLIDFDKLKDSNARHNLEHAFNVAERQLGI 247

Query: 261 PRLLEPEDIMVDTPDEQSIMTYVAQFLERFPELE 294
             LL+PED+  + PDE+SI+TYV  F   F +++
Sbjct: 248 IPLLDPEDVFTENPDEKSIITYVVAFYHYFSKMK 281


>gi|67782319 spectrin beta isoform b [Homo sapiens]
          Length = 2137

 Score =  175 bits (443), Expect = 2e-43
 Identities = 106/274 (38%), Positives = 152/274 (55%), Gaps = 37/274 (13%)

Query: 22  RVQNLQVERENVQKRTFTRWINLHLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLL 81
           R++ L  ERE VQK+TFT+W+N HL + +    + DL+ D++DG++L+ LLEVLSG  L 
Sbjct: 44  RIKALADEREVVQKKTFTKWVNSHLARVS--CRITDLYKDLRDGRMLIKLLEVLSGEMLP 101

Query: 82  HEYKSSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFFQIK 141
              K    RI  L N+ KAL+FL++  V L ++ + +I DGN  LVLGLIW IIL FQI+
Sbjct: 102 KPTKGKM-RIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQ 160

Query: 142 ELTGNLSRNSPSSSLSPGSGGTDSDSSFPPTPTAERSVAISVKDQRKAIKALLAWVQRKT 201
           ++                                        ++ R A  ALL W Q KT
Sbjct: 161 DIVVQTQEG---------------------------------RETRSAKDALLLWCQMKT 187

Query: 202 RKY-GVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHI 260
             Y  V V +F  SW+ GLAF A+I    P L+D  +  +++ R NLE AF++A+  L I
Sbjct: 188 AGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLIDFDKLKDSNARHNLEHAFNVAERQLGI 247

Query: 261 PRLLEPEDIMVDTPDEQSIMTYVAQFLERFPELE 294
             LL+PED+  + PDE+SI+TYV  F   F +++
Sbjct: 248 IPLLDPEDVFTENPDEKSIITYVVAFYHYFSKMK 281


>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
          Length = 4525

 Score =  170 bits (431), Expect = 5e-42
 Identities = 104/272 (38%), Positives = 145/272 (53%), Gaps = 40/272 (14%)

Query: 23  VQNLQVERENVQKRTFTRWINLHLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLH 82
           + +L+ ER+ VQK+TFT+W+N HL K      + DL+ D++DG  L++LLEVLSG +L  
Sbjct: 11  ISSLKDERDRVQKKTFTKWVNKHLIKAQR--HISDLYEDLRDGHNLISLLEVLSGDSLPR 68

Query: 83  EYKSSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFFQIKE 142
           E      R  +L N+  AL +L    VKLV+I   +IADGNP L LGLIW IIL FQI +
Sbjct: 69  E--KGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISD 126

Query: 143 LTGNLSRNSPSSSLSPGSGGTDSDSSFPPTPTAERSVAISVKDQRKAIKALLAWVQRKTR 202
           +                  G   D +                    A + LL W QR   
Sbjct: 127 IQ---------------VSGQSEDMT--------------------AKEKLLLWSQRMVE 151

Query: 203 KY-GVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHIP 261
            Y G+   +F  SWR G  F A+I    P L+DM +    +  ENL++AFS+A+  L + 
Sbjct: 152 GYQGLRCDNFTSSWRDGRLFNAIIHRHKPLLIDMNKVYRQTNLENLDQAFSVAERDLGVT 211

Query: 262 RLLEPEDIMVDTPDEQSIMTYVAQFLERFPEL 293
           RLL+PED+ V  PDE+SI+TYV+   +  P +
Sbjct: 212 RLLDPEDVDVPQPDEKSIITYVSSLYDAMPRV 243


>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
          Length = 4547

 Score =  170 bits (430), Expect = 7e-42
 Identities = 105/271 (38%), Positives = 144/271 (53%), Gaps = 40/271 (14%)

Query: 24  QNLQVERENVQKRTFTRWINLHLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHE 83
           Q+ Q ER+ VQK+TFT+W+N HL K      + DL+ D++DG  L++LLEVLSG +L  E
Sbjct: 34  QDEQDERDRVQKKTFTKWVNKHLIKAQR--HISDLYEDLRDGHNLISLLEVLSGDSLPRE 91

Query: 84  YKSSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFFQIKEL 143
                 R  +L N+  AL +L    VKLV+I   +IADGNP L LGLIW IIL FQI ++
Sbjct: 92  --KGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDI 149

Query: 144 TGNLSRNSPSSSLSPGSGGTDSDSSFPPTPTAERSVAISVKDQRKAIKALLAWVQRKTRK 203
                             G   D +                    A + LL W QR    
Sbjct: 150 Q---------------VSGQSEDMT--------------------AKEKLLLWSQRMVEG 174

Query: 204 Y-GVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHIPR 262
           Y G+   +F  SWR G  F A+I    P L+DM +    +  ENL++AFS+A+  L + R
Sbjct: 175 YQGLRCDNFTSSWRDGRLFNAIIHRHKPLLIDMNKVYRQTNLENLDQAFSVAERDLGVTR 234

Query: 263 LLEPEDIMVDTPDEQSIMTYVAQFLERFPEL 293
           LL+PED+ V  PDE+SI+TYV+   +  P +
Sbjct: 235 LLDPEDVDVPQPDEKSIITYVSSLYDAMPRV 265


>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
          Length = 4533

 Score =  168 bits (426), Expect = 2e-41
 Identities = 105/283 (37%), Positives = 149/283 (52%), Gaps = 41/283 (14%)

Query: 12  EELIGQISDIRVQNLQVERENVQKRTFTRWINLHLEKCNPPLEVKDLFVDIQDGKILMAL 71
           ++ I    ++R +  + ER+ VQK+TFT+W+N HL K      + DL+ D++DG  L++L
Sbjct: 9   QDFIQAYEEVR-EKYKDERDRVQKKTFTKWVNKHLIKAQR--HISDLYEDLRDGHNLISL 65

Query: 72  LEVLSGRNLLHEYKSSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLI 131
           LEVLSG +L  E      R  +L N+  AL +L    VKLV+I   +IADGNP L LGLI
Sbjct: 66  LEVLSGDSLPRE--KGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLI 123

Query: 132 WNIILFFQIKELTGNLSRNSPSSSLSPGSGGTDSDSSFPPTPTAERSVAISVKDQRKAIK 191
           W IIL FQI ++                  G   D +                    A +
Sbjct: 124 WTIILHFQISDIQ---------------VSGQSEDMT--------------------AKE 148

Query: 192 ALLAWVQRKTRKY-GVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKA 250
            LL W QR    Y G+   +F  SWR G  F A+I    P L+DM +    +  ENL++A
Sbjct: 149 KLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNAIIHRHKPLLIDMNKVYRQTNLENLDQA 208

Query: 251 FSIAQDALHIPRLLEPEDIMVDTPDEQSIMTYVAQFLERFPEL 293
           FS+A+  L + RLL+PED+ V  PDE+SI+TYV+   +  P +
Sbjct: 209 FSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVSSLYDAMPRV 251


>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
          Length = 4547

 Score =  168 bits (425), Expect = 3e-41
 Identities = 103/266 (38%), Positives = 141/266 (53%), Gaps = 40/266 (15%)

Query: 29  ERENVQKRTFTRWINLHLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYKSSS 88
           ER+ VQK+TFT+W+N HL K      + DL+ D++DG  L++LLEVLSG +L  E     
Sbjct: 39  ERDRVQKKTFTKWVNKHLIKAQR--HISDLYEDLRDGHNLISLLEVLSGDSLPRE--KGR 94

Query: 89  HRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFFQIKELTGNLS 148
            R  +L N+  AL +L    VKLV+I   +IADGNP L LGLIW IIL FQI ++     
Sbjct: 95  MRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQ---- 150

Query: 149 RNSPSSSLSPGSGGTDSDSSFPPTPTAERSVAISVKDQRKAIKALLAWVQRKTRKY-GVA 207
                        G   D +                    A + LL W QR    Y G+ 
Sbjct: 151 -----------VSGQSEDMT--------------------AKEKLLLWSQRMVEGYQGLR 179

Query: 208 VQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHIPRLLEPE 267
             +F  SWR G  F A+I    P L+DM +    +  ENL++AFS+A+  L + RLL+PE
Sbjct: 180 CDNFTSSWRDGRLFNAIIHRHKPLLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPE 239

Query: 268 DIMVDTPDEQSIMTYVAQFLERFPEL 293
           D+ V  PDE+SI+TYV+   +  P +
Sbjct: 240 DVDVPQPDEKSIITYVSSLYDAMPRV 265


>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
          Length = 4551

 Score =  168 bits (425), Expect = 3e-41
 Identities = 103/266 (38%), Positives = 141/266 (53%), Gaps = 40/266 (15%)

Query: 29  ERENVQKRTFTRWINLHLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYKSSS 88
           ER+ VQK+TFT+W+N HL K      + DL+ D++DG  L++LLEVLSG +L  E     
Sbjct: 43  ERDRVQKKTFTKWVNKHLIKAQR--HISDLYEDLRDGHNLISLLEVLSGDSLPRE--KGR 98

Query: 89  HRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFFQIKELTGNLS 148
            R  +L N+  AL +L    VKLV+I   +IADGNP L LGLIW IIL FQI ++     
Sbjct: 99  MRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQ---- 154

Query: 149 RNSPSSSLSPGSGGTDSDSSFPPTPTAERSVAISVKDQRKAIKALLAWVQRKTRKY-GVA 207
                        G   D +                    A + LL W QR    Y G+ 
Sbjct: 155 -----------VSGQSEDMT--------------------AKEKLLLWSQRMVEGYQGLR 183

Query: 208 VQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHIPRLLEPE 267
             +F  SWR G  F A+I    P L+DM +    +  ENL++AFS+A+  L + RLL+PE
Sbjct: 184 CDNFTSSWRDGRLFNAIIHRHKPLLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPE 243

Query: 268 DIMVDTPDEQSIMTYVAQFLERFPEL 293
           D+ V  PDE+SI+TYV+   +  P +
Sbjct: 244 DVDVPQPDEKSIITYVSSLYDAMPRV 269


>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
          Length = 4515

 Score =  168 bits (425), Expect = 3e-41
 Identities = 103/266 (38%), Positives = 141/266 (53%), Gaps = 40/266 (15%)

Query: 29  ERENVQKRTFTRWINLHLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYKSSS 88
           ER+ VQK+TFT+W+N HL K      + DL+ D++DG  L++LLEVLSG +L  E     
Sbjct: 7   ERDRVQKKTFTKWVNKHLIKAQR--HISDLYEDLRDGHNLISLLEVLSGDSLPRE--KGR 62

Query: 89  HRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFFQIKELTGNLS 148
            R  +L N+  AL +L    VKLV+I   +IADGNP L LGLIW IIL FQI ++     
Sbjct: 63  MRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQ---- 118

Query: 149 RNSPSSSLSPGSGGTDSDSSFPPTPTAERSVAISVKDQRKAIKALLAWVQRKTRKY-GVA 207
                        G   D +                    A + LL W QR    Y G+ 
Sbjct: 119 -----------VSGQSEDMT--------------------AKEKLLLWSQRMVEGYQGLR 147

Query: 208 VQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHIPRLLEPE 267
             +F  SWR G  F A+I    P L+DM +    +  ENL++AFS+A+  L + RLL+PE
Sbjct: 148 CDNFTSSWRDGRLFNAIIHRHKPLLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPE 207

Query: 268 DIMVDTPDEQSIMTYVAQFLERFPEL 293
           D+ V  PDE+SI+TYV+   +  P +
Sbjct: 208 DVDVPQPDEKSIITYVSSLYDAMPRV 233


>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
          Length = 4684

 Score =  168 bits (425), Expect = 3e-41
 Identities = 103/266 (38%), Positives = 141/266 (53%), Gaps = 40/266 (15%)

Query: 29  ERENVQKRTFTRWINLHLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYKSSS 88
           ER+ VQK+TFT+W+N HL K      + DL+ D++DG  L++LLEVLSG +L  E     
Sbjct: 176 ERDRVQKKTFTKWVNKHLIKAQR--HISDLYEDLRDGHNLISLLEVLSGDSLPRE--KGR 231

Query: 89  HRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFFQIKELTGNLS 148
            R  +L N+  AL +L    VKLV+I   +IADGNP L LGLIW IIL FQI ++     
Sbjct: 232 MRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQ---- 287

Query: 149 RNSPSSSLSPGSGGTDSDSSFPPTPTAERSVAISVKDQRKAIKALLAWVQRKTRKY-GVA 207
                        G   D +                    A + LL W QR    Y G+ 
Sbjct: 288 -----------VSGQSEDMT--------------------AKEKLLLWSQRMVEGYQGLR 316

Query: 208 VQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHIPRLLEPE 267
             +F  SWR G  F A+I    P L+DM +    +  ENL++AFS+A+  L + RLL+PE
Sbjct: 317 CDNFTSSWRDGRLFNAIIHRHKPLLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPE 376

Query: 268 DIMVDTPDEQSIMTYVAQFLERFPEL 293
           D+ V  PDE+SI+TYV+   +  P +
Sbjct: 377 DVDVPQPDEKSIITYVSSLYDAMPRV 402


>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
          Length = 4574

 Score =  168 bits (425), Expect = 3e-41
 Identities = 103/266 (38%), Positives = 141/266 (53%), Gaps = 40/266 (15%)

Query: 29  ERENVQKRTFTRWINLHLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYKSSS 88
           ER+ VQK+TFT+W+N HL K      + DL+ D++DG  L++LLEVLSG +L  E     
Sbjct: 66  ERDRVQKKTFTKWVNKHLIKAQR--HISDLYEDLRDGHNLISLLEVLSGDSLPRE--KGR 121

Query: 89  HRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFFQIKELTGNLS 148
            R  +L N+  AL +L    VKLV+I   +IADGNP L LGLIW IIL FQI ++     
Sbjct: 122 MRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQ---- 177

Query: 149 RNSPSSSLSPGSGGTDSDSSFPPTPTAERSVAISVKDQRKAIKALLAWVQRKTRKY-GVA 207
                        G   D +                    A + LL W QR    Y G+ 
Sbjct: 178 -----------VSGQSEDMT--------------------AKEKLLLWSQRMVEGYQGLR 206

Query: 208 VQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHIPRLLEPE 267
             +F  SWR G  F A+I    P L+DM +    +  ENL++AFS+A+  L + RLL+PE
Sbjct: 207 CDNFTSSWRDGRLFNAIIHRHKPLLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPE 266

Query: 268 DIMVDTPDEQSIMTYVAQFLERFPEL 293
           D+ V  PDE+SI+TYV+   +  P +
Sbjct: 267 DVDVPQPDEKSIITYVSSLYDAMPRV 292



 Score = 32.7 bits (73), Expect = 1.8
 Identities = 33/126 (26%), Positives = 53/126 (42%), Gaps = 21/126 (16%)

Query: 105 EDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFFQIKELTGNLSRNSPSSSLSPGSGGTD 164
           ED+ V+ VS D +  + G+PS    L WN+          G   R+  S     G G   
Sbjct: 4   EDAEVRAVSEDVSNGSSGSPSPGDTLPWNL----------GKTQRSRRS-----GGGAGS 48

Query: 165 SDSSFPPTPTAERSVAISVKDQRKAI--KALLAWVQRKTRKYGVAVQDFAGSWRSGLAFL 222
           + S   P   AER+V I + D+R  +  K    WV +   K    + D     R G   +
Sbjct: 49  NGSVLDP---AERAV-IRIADERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLI 104

Query: 223 AVIKAI 228
           ++++ +
Sbjct: 105 SLLEVL 110


>gi|33188445 microfilament and actin filament cross-linker protein
           isoform a [Homo sapiens]
          Length = 5430

 Score =  167 bits (422), Expect = 6e-41
 Identities = 105/266 (39%), Positives = 143/266 (53%), Gaps = 41/266 (15%)

Query: 29  ERENVQKRTFTRWINLHLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYKSSS 88
           ER+ VQK+TFT+W+N HL K      + DL+ D++DG  L++LLEVLSG  L  E     
Sbjct: 75  ERDRVQKKTFTKWVNKHLMKVRK--HINDLYEDLRDGHNLISLLEVLSGIKLPRE--KGR 130

Query: 89  HRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFFQIKELTGNLS 148
            R  RL N+  AL FL+   VKLV+I   +I DGNP L LGLIW IIL FQI ++     
Sbjct: 131 MRFHRLQNVQIALDFLKQRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIY---- 186

Query: 149 RNSPSSSLSPGSGGTDSDSSFPPTPTAERSVAISVKDQRKAIKALLAWVQRKTRKY-GVA 207
                        G   D S                    A + LL W Q+ T  Y G+ 
Sbjct: 187 -----------ISGESGDMS--------------------AKEKLLLWTQKVTAGYTGIK 215

Query: 208 VQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHIPRLLEPE 267
             +F+  W  G  F A+I    P LVDM++    S RENLE+AF +A + L + RLL+ E
Sbjct: 216 CTNFSSCWSDGKMFNALIHRYRPDLVDMERVQIQSNRENLEQAFEVA-ERLGVTRLLDAE 274

Query: 268 DIMVDTPDEQSIMTYVAQFLERFPEL 293
           D+ V +PDE+S++TYV+   + FP++
Sbjct: 275 DVDVPSPDEKSVITYVSSIYDAFPKV 300


>gi|34577047 dystonin isoform 1 [Homo sapiens]
          Length = 5497

 Score =  166 bits (421), Expect = 8e-41
 Identities = 111/301 (36%), Positives = 156/301 (51%), Gaps = 44/301 (14%)

Query: 8   WFQREELIGQISDIRVQNLQVERENVQKRTFTRWINLHLEKCNPPLEVKDLFVDIQDGKI 67
           + + +E +    D+ ++  + ER+ VQK+TFT+WIN HL K      V DL+ D++DG  
Sbjct: 12  YVEEQEYLQAYEDV-LERYKDERDKVQKKTFTKWINQHLMKVRK--HVNDLYEDLRDGHN 68

Query: 68  LMALLEVLSGRNLLHEYKSSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLV 127
           L++LLEVLSG  L  E      R  RL N+  AL +L+   VKLV+I   +I DGNP L 
Sbjct: 69  LISLLEVLSGDTLPRE--KGRMRFHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLT 126

Query: 128 LGLIWNIILFFQIKELTGNLSRNSPSSSLSPGSGGTDSDSSFPPTPTAERSVAISVKDQR 187
           LGLIW IIL FQI ++                  G   D S                   
Sbjct: 127 LGLIWTIILHFQISDIHVT---------------GESEDMS------------------- 152

Query: 188 KAIKALLAWVQRKTRKY-GVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTREN 246
            A + LL W Q+ T  Y G+  ++F   WR G  F A+I    P L+DM      S   N
Sbjct: 153 -AKERLLLWTQQATEGYAGIRCENFTTCWRDGKLFNAIIHKYRPDLIDMNTVAVQSNLAN 211

Query: 247 LEKAFSIAQDALHIPRLLEPEDIMVDTPDEQSIMTYVAQFLERFPELE--AEDIFDSDKE 304
           LE AF +A + + + RLL+PED+ V +PDE+S++TYV+   + FP++    E I  +D E
Sbjct: 212 LEHAFYVA-EKIGVIRLLDPEDVDVSSPDEKSVITYVSSLYDAFPKVPEGGEGIGANDVE 270

Query: 305 V 305
           V
Sbjct: 271 V 271


>gi|110611228 utrophin [Homo sapiens]
          Length = 3433

 Score =  165 bits (418), Expect = 2e-40
 Identities = 108/313 (34%), Positives = 163/313 (52%), Gaps = 44/313 (14%)

Query: 17  QISDIRVQNLQVERENVQKRTFTRWINLHLEKCNPPLEVKDLFVDIQDGKILMALLEVLS 76
           + SDI +++   E  +VQK+TFT+WIN    K   P  + D+F D++DG+ L+ LLE L+
Sbjct: 17  EFSDI-IKSRSDEHNDVQKKTFTKWINARFSKSGKP-PINDMFTDLKDGRKLLDLLEGLT 74

Query: 77  GRNLLHEYKSSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIIL 136
           G +L  E  S+  R+  LNN+ + L+ L  +NV+LV+I   +I DGN  L LGL+W+IIL
Sbjct: 75  GTSLPKERGST--RVHALNNVNRVLQVLHQNNVELVNIGGTDIVDGNHKLTLGLLWSIIL 132

Query: 137 FFQIKELTGNLSRNSPSSSLSPGSGGTDSDSSFPPTPTAERSVAISVKDQRKAIKALLAW 196
            +Q+K++  ++                                 +S   Q  + K LL+W
Sbjct: 133 HWQVKDVMKDV---------------------------------MSDLQQTNSEKILLSW 159

Query: 197 VQRKTRKYG-VAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQ 255
           V++ TR Y  V V +F  SW  GLAF AV+    P L    + ++ S  E LE AFS AQ
Sbjct: 160 VRQTTRPYSQVNVLNFTTSWTDGLAFNAVLHRHKPDLFSWDKVVKMSPIERLEHAFSKAQ 219

Query: 256 DALHIPRLLEPEDIMVDTPDEQSIMTYVAQFLERFPELEAEDIFDSDKEVP------IES 309
             L I +LL+PED+ V  PD++SI+ Y+    E  P+    D     + +P       E 
Sbjct: 220 TYLGIEKLLDPEDVAVQLPDKKSIIMYLTSLFEVLPQQVTIDAIREVETLPRKYKKECEE 279

Query: 310 TFVRIKETPSEQE 322
             + I+ T  E+E
Sbjct: 280 EAINIQSTAPEEE 292


>gi|169218211 PREDICTED: similar to plectin 1, partial [Homo
           sapiens]
          Length = 1369

 Score =  165 bits (417), Expect = 2e-40
 Identities = 102/266 (38%), Positives = 140/266 (52%), Gaps = 40/266 (15%)

Query: 29  ERENVQKRTFTRWINLHLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYKSSS 88
           ER+ VQK+T T+W+N HL K      + DL+ D++DG  L++LLEVLSG +L  E     
Sbjct: 172 ERDRVQKKTSTKWVNKHLIKAQR--HISDLYEDLRDGHNLISLLEVLSGDSLPRE--KGR 227

Query: 89  HRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFFQIKELTGNLS 148
            R  +L N+  AL +L    VKLV+I   +IADGNP L LGLIW IIL FQI ++     
Sbjct: 228 MRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQ---- 283

Query: 149 RNSPSSSLSPGSGGTDSDSSFPPTPTAERSVAISVKDQRKAIKALLAWVQRKTRKY-GVA 207
                        G   D +                    A + LL W QR    Y G+ 
Sbjct: 284 -----------VSGQSEDMT--------------------AKEKLLLWSQRMVEGYQGLR 312

Query: 208 VQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHIPRLLEPE 267
             +F  SWR G  F A+I    P L+DM +    +  ENL++AFS+A+  L + RLL+PE
Sbjct: 313 CDNFTSSWRDGRLFNAIIHRHKPLLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPE 372

Query: 268 DIMVDTPDEQSIMTYVAQFLERFPEL 293
           D+ V  PDE+SI+TYV+   +  P +
Sbjct: 373 DVDVPQPDEKSIITYVSSLYDAMPRV 398


>gi|221316624 dystonin isoform 4 [Homo sapiens]
          Length = 5526

 Score =  165 bits (417), Expect = 2e-40
 Identities = 109/280 (38%), Positives = 146/280 (52%), Gaps = 43/280 (15%)

Query: 29  ERENVQKRTFTRWINLHLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYKSSS 88
           ER+ VQK+TFT+WIN HL K      V DL+ D++DG  L++LLEVLSG  L  E     
Sbjct: 61  ERDKVQKKTFTKWINQHLMKVRK--HVNDLYEDLRDGHNLISLLEVLSGDTLPRE--KGR 116

Query: 89  HRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFFQIKELTGNLS 148
            R  RL N+  AL +L+   VKLV+I   +I DGNP L LGLIW IIL FQI ++     
Sbjct: 117 MRFHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIHVT-- 174

Query: 149 RNSPSSSLSPGSGGTDSDSSFPPTPTAERSVAISVKDQRKAIKALLAWVQRKTRKY-GVA 207
                        G   D S                    A + LL W Q+ T  Y G+ 
Sbjct: 175 -------------GESEDMS--------------------AKERLLLWTQQATEGYAGIR 201

Query: 208 VQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHIPRLLEPE 267
            ++F   WR G  F A+I    P L+DM      S   NLE AF +A + + + RLL+PE
Sbjct: 202 CENFTTCWRDGKLFNAIIHKYRPDLIDMNTVAVQSNLANLEHAFYVA-EKIGVIRLLDPE 260

Query: 268 DIMVDTPDEQSIMTYVAQFLERFPELE--AEDIFDSDKEV 305
           D+ V +PDE+S++TYV+   + FP++    E I  +D EV
Sbjct: 261 DVDVSSPDEKSVITYVSSLYDAFPKVPEGGEGIGANDVEV 300


>gi|221316622 dystonin isoform 3 [Homo sapiens]
          Length = 5537

 Score =  165 bits (417), Expect = 2e-40
 Identities = 109/280 (38%), Positives = 146/280 (52%), Gaps = 43/280 (15%)

Query: 29  ERENVQKRTFTRWINLHLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYKSSS 88
           ER+ VQK+TFT+WIN HL K      V DL+ D++DG  L++LLEVLSG  L  E     
Sbjct: 72  ERDKVQKKTFTKWINQHLMKVRK--HVNDLYEDLRDGHNLISLLEVLSGDTLPRE--KGR 127

Query: 89  HRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFFQIKELTGNLS 148
            R  RL N+  AL +L+   VKLV+I   +I DGNP L LGLIW IIL FQI ++     
Sbjct: 128 MRFHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIHVT-- 185

Query: 149 RNSPSSSLSPGSGGTDSDSSFPPTPTAERSVAISVKDQRKAIKALLAWVQRKTRKY-GVA 207
                        G   D S                    A + LL W Q+ T  Y G+ 
Sbjct: 186 -------------GESEDMS--------------------AKERLLLWTQQATEGYAGIR 212

Query: 208 VQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHIPRLLEPE 267
            ++F   WR G  F A+I    P L+DM      S   NLE AF +A + + + RLL+PE
Sbjct: 213 CENFTTCWRDGKLFNAIIHKYRPDLIDMNTVAVQSNLANLEHAFYVA-EKIGVIRLLDPE 271

Query: 268 DIMVDTPDEQSIMTYVAQFLERFPELE--AEDIFDSDKEV 305
           D+ V +PDE+S++TYV+   + FP++    E I  +D EV
Sbjct: 272 DVDVSSPDEKSVITYVSSLYDAFPKVPEGGEGIGANDVEV 311


>gi|221316618 dystonin isoform 2 [Homo sapiens]
          Length = 5675

 Score =  165 bits (417), Expect = 2e-40
 Identities = 109/280 (38%), Positives = 146/280 (52%), Gaps = 43/280 (15%)

Query: 29  ERENVQKRTFTRWINLHLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYKSSS 88
           ER+ VQK+TFT+WIN HL K      V DL+ D++DG  L++LLEVLSG  L  E     
Sbjct: 210 ERDKVQKKTFTKWINQHLMKVRK--HVNDLYEDLRDGHNLISLLEVLSGDTLPRE--KGR 265

Query: 89  HRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFFQIKELTGNLS 148
            R  RL N+  AL +L+   VKLV+I   +I DGNP L LGLIW IIL FQI ++     
Sbjct: 266 MRFHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIHVT-- 323

Query: 149 RNSPSSSLSPGSGGTDSDSSFPPTPTAERSVAISVKDQRKAIKALLAWVQRKTRKY-GVA 207
                        G   D S                    A + LL W Q+ T  Y G+ 
Sbjct: 324 -------------GESEDMS--------------------AKERLLLWTQQATEGYAGIR 350

Query: 208 VQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHIPRLLEPE 267
            ++F   WR G  F A+I    P L+DM      S   NLE AF +A + + + RLL+PE
Sbjct: 351 CENFTTCWRDGKLFNAIIHKYRPDLIDMNTVAVQSNLANLEHAFYVA-EKIGVIRLLDPE 409

Query: 268 DIMVDTPDEQSIMTYVAQFLERFPELE--AEDIFDSDKEV 305
           D+ V +PDE+S++TYV+   + FP++    E I  +D EV
Sbjct: 410 DVDVSSPDEKSVITYVSSLYDAFPKVPEGGEGIGANDVEV 449


>gi|5032281 dystrophin Dp427c isoform [Homo sapiens]
          Length = 3677

 Score =  162 bits (409), Expect = 2e-39
 Identities = 99/269 (36%), Positives = 149/269 (55%), Gaps = 38/269 (14%)

Query: 26  LQVERENVQKRTFTRWINLHLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYK 85
           ++ ERE+VQK+TFT+W+N    K      +++LF D+QDG+ L+ LLE L+G+ L  E  
Sbjct: 1   MEDEREDVQKKTFTKWVNAQFSKFGKQ-HIENLFSDLQDGRRLLDLLEGLTGQKLPKE-- 57

Query: 86  SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFFQIKELTG 145
             S R+  LNN+ KAL+ L+++NV LV+I + +I DGN  L LGLIWNIIL +Q+K +  
Sbjct: 58  KGSTRVHALNNVNKALRVLQNNNVDLVNIGSTDIVDGNHKLTLGLIWNIILHWQVKNVMK 117

Query: 146 NLSRNSPSSSLSPGSGGTDSDSSFPPTPTAERSVAISVKDQRKAIKALLAWVQRKTRKY- 204
           N+                                 ++   Q  + K LL+WV++ TR Y 
Sbjct: 118 NI---------------------------------MAGLQQTNSEKILLSWVRQSTRNYP 144

Query: 205 GVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQAL-ENSTRENLEKAFSIAQDALHIPRL 263
            V V +F  SW  GLA  A+I +  P L D    + + S  + LE AF+IA+  L I +L
Sbjct: 145 QVNVINFTTSWSDGLALNALIHSHRPDLFDWNSVVCQQSATQRLEHAFNIARYQLGIEKL 204

Query: 264 LEPEDIMVDTPDEQSIMTYVAQFLERFPE 292
           L+PED+    PD++SI+ Y+    +  P+
Sbjct: 205 LDPEDVDTTYPDKKSILMYITSLFQVLPQ 233


>gi|5032287 dystrophin Dp427p1 isoform [Homo sapiens]
          Length = 3681

 Score =  161 bits (408), Expect = 3e-39
 Identities = 99/266 (37%), Positives = 147/266 (55%), Gaps = 38/266 (14%)

Query: 29  ERENVQKRTFTRWINLHLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYKSSS 88
           ERE+VQK+TFT+W+N    K      +++LF D+QDG+ L+ LLE L+G+ L  E    S
Sbjct: 8   EREDVQKKTFTKWVNAQFSKFGKQ-HIENLFSDLQDGRRLLDLLEGLTGQKLPKE--KGS 64

Query: 89  HRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFFQIKELTGNLS 148
            R+  LNN+ KAL+ L+++NV LV+I + +I DGN  L LGLIWNIIL +Q+K +  N+ 
Sbjct: 65  TRVHALNNVNKALRVLQNNNVDLVNIGSTDIVDGNHKLTLGLIWNIILHWQVKNVMKNI- 123

Query: 149 RNSPSSSLSPGSGGTDSDSSFPPTPTAERSVAISVKDQRKAIKALLAWVQRKTRKY-GVA 207
                                           ++   Q  + K LL+WV++ TR Y  V 
Sbjct: 124 --------------------------------MAGLQQTNSEKILLSWVRQSTRNYPQVN 151

Query: 208 VQDFAGSWRSGLAFLAVIKAIDPSLVDMKQAL-ENSTRENLEKAFSIAQDALHIPRLLEP 266
           V +F  SW  GLA  A+I +  P L D    + + S  + LE AF+IA+  L I +LL+P
Sbjct: 152 VINFTTSWSDGLALNALIHSHRPDLFDWNSVVCQQSATQRLEHAFNIARYQLGIEKLLDP 211

Query: 267 EDIMVDTPDEQSIMTYVAQFLERFPE 292
           ED+    PD++SI+ Y+    +  P+
Sbjct: 212 EDVDTTYPDKKSILMYITSLFQVLPQ 237


>gi|5032283 dystrophin Dp427m isoform [Homo sapiens]
          Length = 3685

 Score =  161 bits (408), Expect = 3e-39
 Identities = 99/266 (37%), Positives = 147/266 (55%), Gaps = 38/266 (14%)

Query: 29  ERENVQKRTFTRWINLHLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYKSSS 88
           ERE+VQK+TFT+W+N    K      +++LF D+QDG+ L+ LLE L+G+ L  E    S
Sbjct: 12  EREDVQKKTFTKWVNAQFSKFGKQ-HIENLFSDLQDGRRLLDLLEGLTGQKLPKE--KGS 68

Query: 89  HRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFFQIKELTGNLS 148
            R+  LNN+ KAL+ L+++NV LV+I + +I DGN  L LGLIWNIIL +Q+K +  N+ 
Sbjct: 69  TRVHALNNVNKALRVLQNNNVDLVNIGSTDIVDGNHKLTLGLIWNIILHWQVKNVMKNI- 127

Query: 149 RNSPSSSLSPGSGGTDSDSSFPPTPTAERSVAISVKDQRKAIKALLAWVQRKTRKY-GVA 207
                                           ++   Q  + K LL+WV++ TR Y  V 
Sbjct: 128 --------------------------------MAGLQQTNSEKILLSWVRQSTRNYPQVN 155

Query: 208 VQDFAGSWRSGLAFLAVIKAIDPSLVDMKQAL-ENSTRENLEKAFSIAQDALHIPRLLEP 266
           V +F  SW  GLA  A+I +  P L D    + + S  + LE AF+IA+  L I +LL+P
Sbjct: 156 VINFTTSWSDGLALNALIHSHRPDLFDWNSVVCQQSATQRLEHAFNIARYQLGIEKLLDP 215

Query: 267 EDIMVDTPDEQSIMTYVAQFLERFPE 292
           ED+    PD++SI+ Y+    +  P+
Sbjct: 216 EDVDTTYPDKKSILMYITSLFQVLPQ 241


>gi|12025678 actinin, alpha 4 [Homo sapiens]
          Length = 911

 Score =  150 bits (380), Expect = 4e-36
 Identities = 97/262 (37%), Positives = 134/262 (51%), Gaps = 44/262 (16%)

Query: 31  ENVQKRTFTRWINLHLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYKSSSHR 90
           E  Q++TFT W N HL K    +E  D   D +DG  LM LLEV+SG  L    +    R
Sbjct: 49  EKQQRKTFTAWCNSHLRKAGTQIENID--EDFRDGLKLMLLLEVISGERLPKPERGKM-R 105

Query: 91  IFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFFQIKELTGNLSRN 150
           + ++NN+ KAL F+    VKLVSI A EI DGN  + LG+IW IIL F I++++      
Sbjct: 106 VHKINNVNKALDFIASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDIS------ 159

Query: 151 SPSSSLSPGSGGTDSDSSFPPTPTAERSVAISVKDQRKAIKALLAWVQRKTRKY-GVAVQ 209
                                             ++  A + LL W QRKT  Y  V VQ
Sbjct: 160 ---------------------------------VEETSAKEGLLLWCQRKTAPYKNVNVQ 186

Query: 210 DFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHIPRLLEPEDI 269
           +F  SW+ GLAF A+I    P L++  +  ++    NL  AF +A+  L IP++L+ EDI
Sbjct: 187 NFHISWKDGLAFNALIHRHRPELIEYDKLRKDDPVTNLNNAFEVAEKYLDIPKMLDAEDI 246

Query: 270 M-VDTPDEQSIMTYVAQFLERF 290
           +    PDE++IMTYV+ F   F
Sbjct: 247 VNTARPDEKAIMTYVSSFYHAF 268


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.128    0.358 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,590,234
Number of Sequences: 37866
Number of extensions: 2071706
Number of successful extensions: 10869
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 103
Number of HSP's successfully gapped in prelim test: 411
Number of HSP's that attempted gapping in prelim test: 9325
Number of HSP's gapped (non-prelim): 1632
length of query: 1002
length of database: 18,247,518
effective HSP length: 112
effective length of query: 890
effective length of database: 14,006,526
effective search space: 12465808140
effective search space used: 12465808140
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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