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Search of human proteins with 19923485
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19923485 cisplatin resistance-associated overexpressed
protein [Homo sapiens]
(432 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|52426743 cisplatin resistance-associated overexpressed protei... 849 0.0
gi|19923485 cisplatin resistance-associated overexpressed protei... 849 0.0
gi|116812577 LUC7-like 2 [Homo sapiens] 241 9e-64
gi|41393554 LUC7-like isoform b [Homo sapiens] 212 5e-55
gi|8922297 LUC7-like isoform a [Homo sapiens] 204 1e-52
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 135 9e-32
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 125 1e-28
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 121 1e-27
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 118 1e-26
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 118 1e-26
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 117 2e-26
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 112 7e-25
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 112 7e-25
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 110 3e-24
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 109 6e-24
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 108 1e-23
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 107 2e-23
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 107 2e-23
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 104 1e-22
gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s... 103 3e-22
gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] 102 5e-22
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 102 7e-22
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 101 1e-21
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 97 3e-20
gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo sapi... 96 5e-20
gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens] 95 1e-19
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 94 2e-19
gi|148746195 trichohyalin [Homo sapiens] 92 7e-19
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 91 2e-18
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 91 2e-18
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 849 bits (2194), Expect = 0.0
Identities = 432/432 (100%), Positives = 432/432 (100%)
Query: 1 MISAAQLLDELMGRDRNLAPDEKRSNVRWDHESVCKYYLCGFCPAELFTNTRSDLGPCEK 60
MISAAQLLDELMGRDRNLAPDEKRSNVRWDHESVCKYYLCGFCPAELFTNTRSDLGPCEK
Sbjct: 1 MISAAQLLDELMGRDRNLAPDEKRSNVRWDHESVCKYYLCGFCPAELFTNTRSDLGPCEK 60
Query: 61 IHDENLRKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGAAG 120
IHDENLRKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGAAG
Sbjct: 61 IHDENLRKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGAAG 120
Query: 121 PTGKNEEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLKEERELLRSTTSTIE 180
PTGKNEEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLKEERELLRSTTSTIE
Sbjct: 121 PTGKNEEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLKEERELLRSTTSTIE 180
Query: 181 SFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEE 240
SFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEE
Sbjct: 181 SFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEE 240
Query: 241 PDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHS 300
PDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHS
Sbjct: 241 PDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHS 300
Query: 301 SRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKS 360
SRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKS
Sbjct: 301 SRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKS 360
Query: 361 YKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTS 420
YKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTS
Sbjct: 361 YKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTS 420
Query: 421 EDIKSEGDTQSN 432
EDIKSEGDTQSN
Sbjct: 421 EDIKSEGDTQSN 432
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 849 bits (2194), Expect = 0.0
Identities = 432/432 (100%), Positives = 432/432 (100%)
Query: 1 MISAAQLLDELMGRDRNLAPDEKRSNVRWDHESVCKYYLCGFCPAELFTNTRSDLGPCEK 60
MISAAQLLDELMGRDRNLAPDEKRSNVRWDHESVCKYYLCGFCPAELFTNTRSDLGPCEK
Sbjct: 1 MISAAQLLDELMGRDRNLAPDEKRSNVRWDHESVCKYYLCGFCPAELFTNTRSDLGPCEK 60
Query: 61 IHDENLRKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGAAG 120
IHDENLRKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGAAG
Sbjct: 61 IHDENLRKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGAAG 120
Query: 121 PTGKNEEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLKEERELLRSTTSTIE 180
PTGKNEEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLKEERELLRSTTSTIE
Sbjct: 121 PTGKNEEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLKEERELLRSTTSTIE 180
Query: 181 SFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEE 240
SFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEE
Sbjct: 181 SFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEE 240
Query: 241 PDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHS 300
PDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHS
Sbjct: 241 PDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHS 300
Query: 301 SRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKS 360
SRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKS
Sbjct: 301 SRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKS 360
Query: 361 YKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTS 420
YKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTS
Sbjct: 361 YKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTS 420
Query: 421 EDIKSEGDTQSN 432
EDIKSEGDTQSN
Sbjct: 421 EDIKSEGDTQSN 432
>gi|116812577 LUC7-like 2 [Homo sapiens]
Length = 392
Score = 241 bits (615), Expect = 9e-64
Identities = 144/391 (36%), Positives = 229/391 (58%), Gaps = 23/391 (5%)
Query: 7 LLDELMGRDRNLAPDEKRSNVRWDHESVCKYYLCGFCPAELFTNTRSDLGPCEKIHDENL 66
+LD+LMG R+ D R +++ + VCK +L CP ++ + TR DLG C K+HD L
Sbjct: 10 MLDQLMGTSRD--GDTTRQRIKFSDDRVCKSHLLNCCPHDVLSGTRMDLGECLKVHDLAL 67
Query: 67 RKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGAAGPTGKNE 126
R YE +S+ +E D + +LQS +A+ +RR RLA +Q + S+ A
Sbjct: 68 RADYEIASKEQDFFFELDAMDHLQSFIADCDRRTEVAKKRLAETQEEISAEVAAKA---- 123
Query: 127 EKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLK-EERELLRSTTSTIESFAAQ 185
E++ L ++I LL ++E+LG+EG VEE+Q +M VE+ + ++RE +++ + + Q
Sbjct: 124 ERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMPASSFQ 183
Query: 186 EKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDE 245
++++ VCEVC A+L + D R+ DH GK H+G+ +I+ +EELK + ++ E+ +++
Sbjct: 184 QQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRNQER 243
Query: 246 RLKKEKQEREEREK-EREREREERERKRRREEEEREKERARDRERRKRSRSRS-----RH 299
++E++EREEREK R R + ++ R E R + R+ RER++R+RS+S RH
Sbjct: 244 LKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRH 303
Query: 300 SSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRK 359
SR+S R SRSR H+RSR R RSR R +RRS K R R +D S RDR
Sbjct: 304 RSRSSSR--SRSRSHQRSRHSSRDRSRERSKRRS-------SKERFRDQD-LASCDRDRS 353
Query: 360 SYKHRSKSRDREQDRKSKEKEKRGSDDKKSS 390
S + RDR+ ++S E S+D++SS
Sbjct: 354 SRDRSPRDRDRKDKKRSYESANGRSEDRRSS 384
>gi|41393554 LUC7-like isoform b [Homo sapiens]
Length = 371
Score = 212 bits (540), Expect = 5e-55
Identities = 130/375 (34%), Positives = 209/375 (55%), Gaps = 18/375 (4%)
Query: 7 LLDELMGRDRNLAPDEKRSNVRWDHESVCKYYLCGFCPAELFTNTRSDLGPCEKIHDENL 66
LLD+LMG R+ DE R V++ + VCK +L CP ++ TR DLG C KIHD L
Sbjct: 10 LLDQLMGTARD--GDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECTKIHDLAL 67
Query: 67 RKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGAAGPTGKNE 126
R YE +S+ + +E D + +L+S +AE +RR RLA +Q + S+ +
Sbjct: 68 RADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKA---- 123
Query: 127 EKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLK-EERELLRSTTSTIESFAAQ 185
EK+ L ++I LL + E+LG+EG V+E+Q ++ VE+++ +++E +++ + + Q
Sbjct: 124 EKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQ 183
Query: 186 EKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDE 245
++++ VCEVC A+L + D R+ DH GK H+G+ +I+ +++L++ + ++ E+ ++D
Sbjct: 184 QQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDR 243
Query: 246 RLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSD 305
++E++EREER R R R+ R + R + R+ RERRK SRSRSR R
Sbjct: 244 LRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR--- 300
Query: 306 RRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRS 365
R SRSR H R RR SR R + S +R+ R+ S R R
Sbjct: 301 RHRSRSRSHSRG---HRRASRDRSAKYKFSRERASREESWESGRSERGPPDWR-----LE 352
Query: 366 KSRDREQDRKSKEKE 380
S + R+S+EKE
Sbjct: 353 SSNGKMASRRSEEKE 367
Score = 63.2 bits (152), Expect = 5e-10
Identities = 57/227 (25%), Positives = 102/227 (44%), Gaps = 21/227 (9%)
Query: 221 AKIKATVEELKE------KLRKRTEEPDRDERLKKEKQEREEREKERERERE-ERERKRR 273
A++ A E++ E KL + E+ + + + ++ E EK R +++E E E +
Sbjct: 117 AEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNS 176
Query: 274 REEEEREKERARDRERRKRSRSRSRHSSRTSDR----------RCSRSRDHKRSRSRERR 323
++++ R E + R +D + D R E++
Sbjct: 177 MPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQ 236
Query: 324 RSRSRDR-RRSRSHDRSERKHR---SRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEK 379
R++DR RR +R ER R SR+RDRRRS+SRDR+ + RS SR+R + +S+ +
Sbjct: 237 EKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSR 296
Query: 380 EKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSE 426
++ +S S + S D + + K S + + E +SE
Sbjct: 297 DRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGRSE 343
>gi|8922297 LUC7-like isoform a [Homo sapiens]
Length = 325
Score = 204 bits (519), Expect = 1e-52
Identities = 118/326 (36%), Positives = 191/326 (58%), Gaps = 13/326 (3%)
Query: 7 LLDELMGRDRNLAPDEKRSNVRWDHESVCKYYLCGFCPAELFTNTRSDLGPCEKIHDENL 66
LLD+LMG R+ DE R V++ + VCK +L CP ++ TR DLG C KIHD L
Sbjct: 10 LLDQLMGTARD--GDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECTKIHDLAL 67
Query: 67 RKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGAAGPTGKNE 126
R YE +S+ + +E D + +L+S +AE +RR RLA +Q + S+ +
Sbjct: 68 RADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKA---- 123
Query: 127 EKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLK-EERELLRSTTSTIESFAAQ 185
EK+ L ++I LL + E+LG+EG V+E+Q ++ VE+++ +++E +++ + + Q
Sbjct: 124 EKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQ 183
Query: 186 EKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDE 245
++++ VCEVC A+L + D R+ DH GK H+G+ +I+ +++L++ + ++ E+ ++D
Sbjct: 184 QQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDR 243
Query: 246 RLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSD 305
++E++EREER R R R+ R + R + R+ RERRK SRSRSR R
Sbjct: 244 LRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR--- 300
Query: 306 RRCSRSRDHKRSRSRERRRSRSRDRR 331
R SRSR H R RR SR R +
Sbjct: 301 RHRSRSRSHSRG---HRRASRDRSAK 323
Score = 62.0 bits (149), Expect = 1e-09
Identities = 53/209 (25%), Positives = 95/209 (45%), Gaps = 21/209 (10%)
Query: 221 AKIKATVEELKE------KLRKRTEEPDRDERLKKEKQEREEREKERERERE-ERERKRR 273
A++ A E++ E KL + E+ + + + ++ E EK R +++E E E +
Sbjct: 117 AEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNS 176
Query: 274 REEEEREKERARDRERRKRSRSRSRHSSRTSDR----------RCSRSRDHKRSRSRERR 323
++++ R E + R +D + D R E++
Sbjct: 177 MPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQ 236
Query: 324 RSRSRDR-RRSRSHDRSERKHR---SRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEK 379
R++DR RR +R ER R SR+RDRRRS+SRDR+ + RS SR+R + +S+ +
Sbjct: 237 EKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSR 296
Query: 380 EKRGSDDKKSSVKSGSREKQSEDTNTESK 408
++ +S S + S D + + K
Sbjct: 297 DRHRRHRSRSRSHSRGHRRASRDRSAKYK 325
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 135 bits (339), Expect = 9e-32
Identities = 72/180 (40%), Positives = 109/180 (60%), Gaps = 3/180 (1%)
Query: 223 IKATVEELKEKLRKRTEEPDRDERLKKE-KQEREEREKEREREREERERKRRRE-EEERE 280
I + + ++ +K EE + E+ ++E ++ER ERE+ERERERE RER+R RE E ERE
Sbjct: 277 ISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERERERERERE 336
Query: 281 KERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSE 340
KE+ R+RE R+R R R R R DR R RD R RS +R + RSR R +SR +R
Sbjct: 337 KEKERERE-RERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERER 395
Query: 341 RKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQS 400
+ R R R+R R + R+R+ + R + R+RE+D+K +E ++ ++ REK++
Sbjct: 396 EREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEA 455
Score = 132 bits (331), Expect = 8e-31
Identities = 77/228 (33%), Positives = 120/228 (52%), Gaps = 16/228 (7%)
Query: 221 AKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRRE-EEER 279
+K + T ++L+E+ K+ +E E+ ++E++ ERE+ER ERER+R RE E+ER
Sbjct: 282 SKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKER 341
Query: 280 EKERARDRER-RKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDR 338
E+ER RDR+R R + R R R R DR RS D + RSR R +SR R+R R R +R
Sbjct: 342 ERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERER 401
Query: 339 SERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQD-----------RKSKEKEKRGSDDK 387
+ R R R+R R + R+R+ + + K RDRE+D RK +EKE +
Sbjct: 402 EREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERL 461
Query: 388 KS---SVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEGDTQSN 432
K+ + +RE + E E + + E E ++ D + +
Sbjct: 462 KNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDD 509
Score = 125 bits (315), Expect = 6e-29
Identities = 71/184 (38%), Positives = 107/184 (58%), Gaps = 9/184 (4%)
Query: 227 VEELKEKLRKRTEEPDRD--ERLKKEKQEREEREKEREREREERERKRRREEEEREKERA 284
+EE K L R RD ++L++EK ++E+ +E E+ER ERER+R RE E RE+ER
Sbjct: 269 MEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERE 328
Query: 285 RDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHR 344
R+RER R + R +R R RD + R R+R R R RDR R RS DR+ K R
Sbjct: 329 RERERE-----REKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRN--KDR 381
Query: 345 SRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTN 404
SRSR++ R + R+R+ + R + R+RE++R+ + + +R + ++ K RE+ ED
Sbjct: 382 SRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAY 441
Query: 405 TESK 408
K
Sbjct: 442 ERRK 445
Score = 99.0 bits (245), Expect = 7e-21
Identities = 76/279 (27%), Positives = 125/279 (44%), Gaps = 77/279 (27%)
Query: 228 EELKEKLRKRTEEPDRDERLKKEKQERE-EREKERERERE-ERERKRRREEE---EREKE 282
+E +E+ R+R E +R ER ++ ++ERE E+EKERERERE +R+R R +E + +RE++
Sbjct: 307 KERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERD 366
Query: 283 RARDRER---RKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRS 339
R RDRER R + RSRSR SR +R R R+ +R R RER R R R+R R R +R
Sbjct: 367 RDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERERERE 426
Query: 340 ERKHRSRSRD------------------------------------------------RR 351
+ K R R D RR
Sbjct: 427 KDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERR 486
Query: 352 RSKSRDRKSYKH--------------------RSKSRDREQDRKSKEKEKRGSDDKKSSV 391
R +++ K K + + RDRE++ ++ E++++ ++ +
Sbjct: 487 REMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEI 546
Query: 392 KSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEGDTQ 430
+ + D + E + + + E IK E +++
Sbjct: 547 RQRLLAEGHPDPDAELQRMEQEAE-RRRQPQIKQEPESE 584
Score = 98.6 bits (244), Expect = 1e-20
Identities = 91/384 (23%), Positives = 163/384 (42%), Gaps = 74/384 (19%)
Query: 101 RRGHARLALSQNQQSSGAAGPT--GKNEEK-----IQVLTDKIDVLLQQIEELGSEGKVE 153
R+ H L +N ++ G G EK I+ L K ++L G+ GK++
Sbjct: 68 RKDHPGLKAKENDENCGPTTTVFVGNISEKASDMLIRQLLAKCGLVLSWKRVQGASGKLQ 127
Query: 154 --------EAQGMMKLVEQLKE----ERELL----RSTTSTIESFAAQEKQMEVCEVCGA 197
E + ++ + L + E++LL T + ++ + A++K
Sbjct: 128 AFGFCEYKEPESTLRALRLLHDLQIGEKKLLVKVDAKTKAQLDEWKAKKKASN--GNARP 185
Query: 198 FLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREE- 256
+ D + +D+ + M I+ + E +L ++E D R KK+K+++E+
Sbjct: 186 ETVTNDDEEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPR-KKKKEKKEDI 244
Query: 257 ----------------REKEREREREE-------------RERKRRREEEEREKERAR-- 285
+E E EE R+ ++ EEE+ +KE+ R
Sbjct: 245 FRRFPVAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQE 304
Query: 286 -DRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHR 344
++ERR+R R R R R R+ +R R RER R + ++R R R DR + +
Sbjct: 305 IEKERRERERERERERER---------REREREREREREREKEKERERERERDRDRDRTK 355
Query: 345 SRSRDRRRSKSRDR------KSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREK 398
R RDR R + RDR K RS+SR++ +DR+ + + +R + ++ + RE+
Sbjct: 356 ERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERER 415
Query: 399 QSEDTNTESKESDTKNEVNGTSED 422
+ E +E D K + ED
Sbjct: 416 EREREREREREKDKKRDREEDEED 439
Score = 68.2 bits (165), Expect = 1e-11
Identities = 56/209 (26%), Positives = 99/209 (47%), Gaps = 29/209 (13%)
Query: 228 EELKEKLRKRTEEPDRD-ERLKKEKQERE-EREKEREREREERERKRRREEEEREKERAR 285
E +E+ R+R E +R+ ER ++ ++ERE +++++RE + E+ +R+ E + REKE A
Sbjct: 398 EREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAY 457
Query: 286 DRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSR------SRDRRRSRSHDRS 339
+ER K R R +R ++ R + +R ++E +R + DR + + S
Sbjct: 458 -QERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGS 516
Query: 340 ERKHRSRSRDRR-RSKSRDRKSYKHRSK------------SRDREQDRKSKEKEKRGSDD 386
+ R R R++ + RDRK K + D E R +E E+R
Sbjct: 517 ALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQ 576
Query: 387 KKSSVKSGSREKQSEDTNTESKESDTKNE 415
K +E +SE+ E +E + K E
Sbjct: 577 IK-------QEPESEEEEEEKQEKEEKRE 598
Score = 62.4 bits (150), Expect = 8e-10
Identities = 55/210 (26%), Positives = 92/210 (43%), Gaps = 11/210 (5%)
Query: 228 EELKEKLRKRTE-EPDRDERLKKEK--QEREEREKEREREREERERKRRRE-EEEREKER 283
E K+K R R E E D ER K E+ +E+E +ER + E RERK+ RE E+E E+E
Sbjct: 424 EREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREE 483
Query: 284 ARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKH 343
R RE K ++ D RD + + R RDR + D +RK
Sbjct: 484 ERRREMAKEAKRLKEFLEDYDD-----DRDDPKYYRGSALQKRLRDREKEMEADERDRKR 538
Query: 344 RSRSRD--RRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSE 401
+ R+R + + ++E +R+ + + K+ + ++ + +E++ E
Sbjct: 539 EKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKRE 598
Query: 402 DTNTESKESDTKNEVNGTSEDIKSEGDTQS 431
+ E +E + K + T I S S
Sbjct: 599 EPMEEEEEPEQKPCLKPTLRPISSAPSVSS 628
Score = 37.4 bits (85), Expect = 0.027
Identities = 35/161 (21%), Positives = 70/161 (43%), Gaps = 13/161 (8%)
Query: 222 KIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREK 281
K++ +E+L+ + R +++ EREE E+ RE +E + K E+ + ++
Sbjct: 449 KLREKEAAYQERLKNWEIRERKKTREYEKEAEREE-ERRREMAKEAKRLKEFLEDYDDDR 507
Query: 282 ERAR-DRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSE 340
+ + R + R R R +D RD KR + E R R +E
Sbjct: 508 DDPKYYRGSALQKRLRDREKEMEAD-----ERDRKREK-EELEEIRQRLLAEGHPDPDAE 561
Query: 341 RKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEK 381
+ + +RRR + K +S + E++++ KE+++
Sbjct: 562 LQRMEQEAERRR-----QPQIKQEPESEEEEEEKQEKEEKR 597
Score = 33.9 bits (76), Expect = 0.29
Identities = 15/51 (29%), Positives = 31/51 (60%)
Query: 221 AKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERK 271
A+++ +E + + + + ++ E ++EKQE+EE+ +E E EE E+K
Sbjct: 560 AELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQK 610
Score = 32.0 bits (71), Expect = 1.1
Identities = 17/63 (26%), Positives = 36/63 (57%), Gaps = 3/63 (4%)
Query: 224 KATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKER 283
K +EE++++L PD D L++ +QE E R + + ++ E E + EE++ ++E+
Sbjct: 540 KEELEEIRQRLLAEGH-PDPDAELQRMEQEAERRRQPQIKQEPESEEEE--EEKQEKEEK 596
Query: 284 ARD 286
+
Sbjct: 597 REE 599
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 125 bits (313), Expect = 1e-28
Identities = 67/210 (31%), Positives = 116/210 (55%), Gaps = 13/210 (6%)
Query: 228 EELKEKLRKRTEEPDRDERLKKEKQEREEREKERERERE-ERERKRRREEE---EREKER 283
E +E+ R+R E + + + + +++ +R+ ERERE++ ERER RE E ERE+ER
Sbjct: 207 ERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERER 266
Query: 284 ARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKH 343
RDR+R +R + R R + R RR R R+ +R R R+R R R R+R R R +R +
Sbjct: 267 DRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERE 326
Query: 344 RSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKS---------KEKEKRGSDDKKSSVKSG 394
R R R+ R + ++R+ + R DRE++R++ +E+E+ D++S+ +
Sbjct: 327 RERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSARERE 386
Query: 395 SREKQSEDTNTESKESDTKNEVNGTSEDIK 424
RE+ + + +E T+ + +G E K
Sbjct: 387 ERERDRDRDRQKERERQTEKDRDGQRETEK 416
Score = 124 bits (310), Expect = 2e-28
Identities = 67/175 (38%), Positives = 103/175 (58%), Gaps = 4/175 (2%)
Query: 228 EELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDR 287
E ++ R+R E DR+ K+E+Q ERE+ER R+RE RER+R R E ER++E RDR
Sbjct: 280 ERQTDRKRQRRTERDRETERKRERQRERERERERNRKRE-RERERER-ERERQRETERDR 337
Query: 288 ERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSER-KHRSR 346
E ++R R R R + +R R+ +R RER R R RDR+ +R + ER + R R
Sbjct: 338 E-KERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDR 396
Query: 347 SRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSE 401
++R R +DR + K R+RE+DR+S+ +RG + +K + RE+Q++
Sbjct: 397 QKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTD 451
Score = 118 bits (295), Expect = 1e-26
Identities = 68/192 (35%), Positives = 113/192 (58%), Gaps = 9/192 (4%)
Query: 231 KEKLRKRTEEPDRDERLKKEK-QERE-EREKERERERE-ERERKRRREEEEREKERARDR 287
+E+ R+R E +R+++ ++E+ ERE ER+KERERER+ +R+R RR++E ER+ +R R R
Sbjct: 230 RERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQR 289
Query: 288 ER---RKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHR 344
R+ R R R R +R +R R+ +R R RER R R +R R + +R ++
Sbjct: 290 RTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQT 349
Query: 345 SRSRDRRRSKSRDRKSYKHRSKSRDREQDRKS-KEKEKRGSDDKKSSVKSGSREKQSEDT 403
R+R R R+ + R + R+RE+DR+S +E+E+R D + K RE+Q+E
Sbjct: 350 EMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQK--ERERQTEKD 407
Query: 404 NTESKESDTKNE 415
+E++ + E
Sbjct: 408 RDGQRETEKQRE 419
Score = 113 bits (283), Expect = 3e-25
Identities = 63/213 (29%), Positives = 114/213 (53%), Gaps = 10/213 (4%)
Query: 228 EELKEKLRKRTEEPDRDERLKKEKQEREEREKERERERE-ERERKRRREEE-EREKERAR 285
E +EK R R + R+ + +EK+ + ++ER+R+RE ER R++ RE E ERE ER R
Sbjct: 80 ERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGR 139
Query: 286 DRE---RRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDR---- 338
DR+ +R+R R R R R R +R+R +ER R ++R RR R R
Sbjct: 140 DRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKEN 199
Query: 339 -SERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSRE 397
+E +H R R+R R + + ++ + R R+R++ RK++ + ++ ++ +++S + R+
Sbjct: 200 KTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERD 259
Query: 398 KQSEDTNTESKESDTKNEVNGTSEDIKSEGDTQ 430
K+ E ++ D + + D K + T+
Sbjct: 260 KERERERDRDRDRDRRQKERERQTDRKRQRRTE 292
Score = 113 bits (283), Expect = 3e-25
Identities = 65/197 (32%), Positives = 105/197 (53%), Gaps = 19/197 (9%)
Query: 232 EKLRKRTEEPDRDERLKKEKQEREEREKERERERE-ERERKRRREEEEREKERARDRER- 289
EK R+R + +R + ++ +Q+ EREK R+ RE ER+R++ + E+R ER R+RER
Sbjct: 156 EKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERE 215
Query: 290 --------RKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSER 341
RKR R R R ++R + + +R+ RE R + R+R R R DR R
Sbjct: 216 RETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRR 275
Query: 342 -KHRSRSRDRRRSK--SRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREK 398
K R R DR+R + RDR++ + R + R+RE++R+ K +R + ++ RE+
Sbjct: 276 QKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERER------ERER 329
Query: 399 QSEDTNTESKESDTKNE 415
Q E KE + K +
Sbjct: 330 QRETERDREKERERKRK 346
Score = 112 bits (280), Expect = 7e-25
Identities = 68/220 (30%), Positives = 111/220 (50%), Gaps = 31/220 (14%)
Query: 231 KEKLRKRTEEPDRDERLKKEKQEREEREKERERERE-----------ERERKR------- 272
+EK R+R + +RD + +KE+ ++ERE+E ERE E ERER+R
Sbjct: 101 REKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERE 160
Query: 273 --------RREEEEREKERARDR---ERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRE 321
R+ E R+KER R++ ERR+R R R + + +T DR R R+ +R R E
Sbjct: 161 RQTDRERQRQTERNRQKEREREKNRQERRERERQREKEN-KTEDRHSERGRERERERETE 219
Query: 322 RRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEK 381
R R R R R + R + +R R+ R+ + K R + RDR++DR ++KE+
Sbjct: 220 TETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKER 279
Query: 382 RGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSE 421
D+K ++ R++++E +E + + E N E
Sbjct: 280 ERQTDRKRQRRT-ERDRETERKRERQRERERERERNRKRE 318
Score = 111 bits (278), Expect = 1e-24
Identities = 63/200 (31%), Positives = 106/200 (53%), Gaps = 3/200 (1%)
Query: 218 MGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEE 277
+G ++ T+ + R ++E R L + ++ + ++ER R++E RER+R + +
Sbjct: 13 LGTLWVEVTIPLDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKE-RERRREKRQT 71
Query: 278 EREKERARDRERRK-RSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSH 336
ERE +R R+R R K R R R RH R DR R R R R R+R + R+R + R R
Sbjct: 72 ERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERET 131
Query: 337 DRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSR 396
+R + R R D +R + R R + K R + DRE+ R+++ ++ + +K+ + R
Sbjct: 132 EREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRER 191
Query: 397 EKQSEDTN-TESKESDTKNE 415
E+Q E N TE + S+ E
Sbjct: 192 ERQREKENKTEDRHSERGRE 211
Score = 111 bits (277), Expect = 1e-24
Identities = 66/206 (32%), Positives = 111/206 (53%), Gaps = 19/206 (9%)
Query: 228 EELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREE-RERKRRREEE-EREKERAR 285
E ++K R+R E + ER K+ER REK+R R+R+ RER+R RE+E ER+ +R R
Sbjct: 55 ERNRQKERERRREKRQTERETDRKRERR-REKDRHRKRDRHRERQRDREKERERQTDRER 113
Query: 286 DRERRK-------RSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDR 338
DR+R K R R R R DR+ R+ +R R E+ R R DR R R +R
Sbjct: 114 DRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTER 173
Query: 339 SERKHRSRSRDRRRSKSRDRKSYK---------HRSKSRDREQDRKSKEKEKRGSDDKKS 389
+ +K R R ++R+ + R+R+ K R + R+RE++ +++ + KR +D ++
Sbjct: 174 NRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERD 233
Query: 390 SVKSGSREKQSEDTNTESKESDTKNE 415
+ RE++ + + E +T+ +
Sbjct: 234 RQRKTEREREKQAERERASERETERD 259
Score = 110 bits (274), Expect = 3e-24
Identities = 61/179 (34%), Positives = 101/179 (56%), Gaps = 9/179 (5%)
Query: 239 EEPDRDERLKKEKQEREEREKERERERE-ERERKRRREEE-----EREKERARDRER-RK 291
++ D D+R + ++ERE R ++R+ ERE +R+R+RRRE++ +R +ER RDRE+ R+
Sbjct: 47 KDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERE 106
Query: 292 RSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRR 351
R R R R +R + R+ + R ER R R D +R R R K R R DR
Sbjct: 107 RQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRE 166
Query: 352 RSKSRDRKSYKHRSKSRDREQDR-KSKEKEKRGSDDKKSSVKSGSREKQSE-DTNTESK 408
R + +R K R + ++R++ R + +++EK + + S + RE++ E +T TE K
Sbjct: 167 RQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERK 225
Score = 109 bits (272), Expect = 6e-24
Identities = 58/191 (30%), Positives = 102/191 (53%), Gaps = 7/191 (3%)
Query: 232 EKLRKRTEEPDRDERLKKEKQEREEREKERERERE-ERERKRRRE-EEEREKERARDRER 289
E+ R R + R+ +++ ++ ER+ +RER+R+ ER R++ RE E+ R++ R R+R+R
Sbjct: 136 ERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQR 195
Query: 290 RKRSRSRSRHSSRTSDRRCSR----SRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRS 345
K +++ RHS R +R R + KR RER R R +R R + +R R
Sbjct: 196 EKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERE 255
Query: 346 RSRDRRRSKSRDR-KSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTN 404
RD+ R + RDR + R K R+R+ DRK + + +R + ++ + RE++ E
Sbjct: 256 TERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNR 315
Query: 405 TESKESDTKNE 415
+E + + E
Sbjct: 316 KRERERERERE 326
Score = 107 bits (266), Expect = 3e-23
Identities = 61/165 (36%), Positives = 96/165 (58%), Gaps = 8/165 (4%)
Query: 228 EELKEKLRKRTEEPDRDERLKKEKQEREEREKER--ERERE-ERERKRRREEE-EREKER 283
E +E+ R+R E +R+ + ++E++ ERE++R ER+RE ERERKR+R+ E +RE+ R
Sbjct: 298 ERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNR 357
Query: 284 ARDRERRK---RSRSRSRHSSRTSDR-RCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRS 339
RE R+ R R R R R S R R R RD R R +ER R +DR R ++
Sbjct: 358 QTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQ 417
Query: 340 ERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGS 384
+ + R +R R + R+R+ K R + R+R+ DR++ + KR +
Sbjct: 418 REREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRST 462
Score = 66.6 bits (161), Expect = 4e-11
Identities = 52/192 (27%), Positives = 93/192 (48%), Gaps = 6/192 (3%)
Query: 231 KEKLRKRTEEPDRD-ERLKKEKQEREEREKERERERE-ERERKRRREEE-EREKERARDR 287
+E R+ E +R+ ER ++ +EREERE++R+R+R+ ERER+ ++ + +RE E+ R+R
Sbjct: 361 REGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQRER 420
Query: 288 ERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRS 347
E+ + S R R R +++ R RD +R R+ R R R R+ R +S
Sbjct: 421 EKDRES-ERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQS 479
Query: 348 RDRRRSKSRDRKSYKHRSKSRDRE--QDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNT 405
R ++ KS K+ R +K R + ++ + G + Q +
Sbjct: 480 DPNRPTRGIRWKSSPEDPKAASTRFPWGRPAKASRGRVAGRRRWEPRLGEKRGQGGEGRR 539
Query: 406 ESKESDTKNEVN 417
S T+N ++
Sbjct: 540 PSGGFGTENPLS 551
Score = 65.9 bits (159), Expect = 7e-11
Identities = 57/192 (29%), Positives = 91/192 (47%), Gaps = 19/192 (9%)
Query: 228 EELKEKLRKRTEEPDRDERLKKEKQERE-----EREKERERERE-------ERERKRRRE 275
E ++ R+R E +RD + +E++ERE +R+KERER+ E E E++R RE
Sbjct: 362 EGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQRERE 421
Query: 276 ---EEEREKERARDRERRK-RSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRS--RSRD 329
E ER +ER R+RE++K R R R R + R + R+ RS + R R +S
Sbjct: 422 KDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDP 481
Query: 330 RRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKS 389
R +R ++ R R K+ + R R R + R EK +G + ++
Sbjct: 482 NRPTRGIRWKSSPEDPKAASTRFPWGRPAKASRGRVAGRRRWEPRLG-EKRGQGGEGRRP 540
Query: 390 SVKSGSREKQSE 401
S G+ S+
Sbjct: 541 SGGFGTENPLSQ 552
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 121 bits (303), Expect = 1e-27
Identities = 70/194 (36%), Positives = 105/194 (54%), Gaps = 18/194 (9%)
Query: 232 EKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEE---EREKERARDRE 288
E+ R+R E DR + ++E+ + ERE + ERE R+R R RE + +REKER R +E
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
Query: 289 RRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRS--- 345
R R R R R + R ++R+ R R +R R +R R + RDR R R DR+ ++R
Sbjct: 62 R-DRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGR 120
Query: 346 -------RSRDRRRSKSRDRKSYKHRSKSRDREQDRKSK---EKEKRGSDDKKSSVKSGS 395
R RDR R + R R+ + R + R RE DR+ + E+E+R + KK K
Sbjct: 121 ERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKER-KKER 179
Query: 396 REKQSEDTNTESKE 409
+EK+ E+ E K+
Sbjct: 180 KEKKKEEKRREDKK 193
Score = 115 bits (287), Expect = 1e-25
Identities = 63/166 (37%), Positives = 104/166 (62%), Gaps = 6/166 (3%)
Query: 226 TVEELKEKLRKRTEEPDRDERLKKEKQEREEREKERERERE-ERERKRRRE-EEEREKER 283
T E + + R R E DR +KE++ ++ER+++R+RERE ERE +R+RE + +RE++R
Sbjct: 31 TERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKR 90
Query: 284 ARDRERRK-RSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERK 342
DRER K R R R R + R +R +R +R + ER R R R+R+R R +R ++
Sbjct: 91 QTDRERDKDRDRERKRETDRNRER--NRKGGRERDKQTERERDRERERQRQRERERQRQR 148
Query: 343 HRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKK 388
R R DR R + +R+ K + + ++R+++RK K+KE++ +DKK
Sbjct: 149 ERKRETDRERQRWAEREERK-KERKKERKKERKEKKKEEKRREDKK 193
Score = 114 bits (286), Expect = 1e-25
Identities = 65/180 (36%), Positives = 106/180 (58%), Gaps = 11/180 (6%)
Query: 228 EELKEKLRKRTEEPDRDERLKKEKQERE-EREKERERERE---ERERKRRREEE-EREKE 282
E +++ R+R + +R+ R ++ + RE +R+ +RE+ERE ER+R+R+RE E ERE E
Sbjct: 18 ERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETE 77
Query: 283 RARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERK 342
R R+R+ R+R R R R DR R R+ R+R R R+ R RD++ R DR +
Sbjct: 78 RQRERQ-RQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERER 136
Query: 343 HRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSED 402
R R R+R+R + R R++ + R + +RE+ +K ++KE+ KK + EK+ ED
Sbjct: 137 QRQRERERQRQRERKRETDRERQRWAEREERKKERKKER-----KKERKEKKKEEKRRED 191
Score = 110 bits (274), Expect = 3e-24
Identities = 56/189 (29%), Positives = 98/189 (51%), Gaps = 2/189 (1%)
Query: 240 EPDRDERLKKEKQEREEREKEREREREER-ERKRRREEEEREKERARDRERRK-RSRSRS 297
E R+ + + ++ + ERE++R+RERE + ER+ R + +R +ER R +R K R R +
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
Query: 298 RHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRD 357
R R +R R + +R R R+R R R DR R + DR ++ R+R+R R R+
Sbjct: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRE 121
Query: 358 RKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVN 417
R R + R+RE+ R+ + + +R + K+ + + R + E+ E K+ K
Sbjct: 122 RDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKE 181
Query: 418 GTSEDIKSE 426
E+ + E
Sbjct: 182 KKKEEKRRE 190
Score = 109 bits (272), Expect = 6e-24
Identities = 55/152 (36%), Positives = 91/152 (59%), Gaps = 5/152 (3%)
Query: 231 KEKLRKRTEEPDRDERLKKEKQEREEREKERERERE-ERERKR-RREEEEREKERARDRE 288
+E+ R+ E +R+ + ++++Q + ERE ERE ER+ ER+R+R R+ + +RE+++ RDRE
Sbjct: 44 RERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRE 103
Query: 289 RRK---RSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRS 345
R++ R+R R+R R D++ R RD +R R R+R R R R R R R DR ++
Sbjct: 104 RKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAE 163
Query: 346 RSRDRRRSKSRDRKSYKHRSKSRDREQDRKSK 377
R ++ K +K K + K R +D+K K
Sbjct: 164 REERKKERKKERKKERKEKKKEEKRREDKKRK 195
Score = 73.6 bits (179), Expect = 3e-13
Identities = 41/141 (29%), Positives = 73/141 (51%), Gaps = 10/141 (7%)
Query: 215 KQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRR 274
+Q + + E +E+ R+R + D K++ +RE +R RER + + R
Sbjct: 64 RQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERD 123
Query: 275 EEEEREKERARDRER-RKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRS 333
++ ERE++R R+R+R R+R R R R R +DR +R R E R R ++R++
Sbjct: 124 KQTERERDRERERQRQRERERQRQRERKRETDR--------ERQRWAE-REERKKERKKE 174
Query: 334 RSHDRSERKHRSRSRDRRRSK 354
R +R E+K + R+ ++ K
Sbjct: 175 RKKERKEKKKEEKRREDKKRK 195
Score = 65.5 bits (158), Expect = 9e-11
Identities = 31/118 (26%), Positives = 64/118 (54%), Gaps = 1/118 (0%)
Query: 310 RSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRD 369
R R+ KR R + R RDR+R R + ++ER++R R RDR R + R K R + ++
Sbjct: 3 RQRERKRETDRGKETERERDRQREREN-QTERENRHRQRDRHRERDRQTDREKERERQKE 61
Query: 370 REQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEG 427
R++ R+ + + +R ++ ++ + R++Q++ + ++ + K E + E + G
Sbjct: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGG 119
Score = 52.4 bits (124), Expect = 8e-07
Identities = 22/92 (23%), Positives = 54/92 (58%)
Query: 205 QSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKERERE 264
+ R D + G + E +++ R+R + +R+ + ++E++ +RE++R E
Sbjct: 104 RKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAE 163
Query: 265 REERERKRRREEEEREKERARDRERRKRSRSR 296
REER+++R++E ++ KE+ ++ +RR+ + +
Sbjct: 164 REERKKERKKERKKERKEKKKEEKRREDKKRK 195
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 118 bits (295), Expect = 1e-26
Identities = 60/190 (31%), Positives = 110/190 (57%), Gaps = 5/190 (2%)
Query: 243 RDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSR 302
R+ KKE++ERE+R++ERE+ER+ RER ++ +++ +++ER ++RER+++ R + R R
Sbjct: 32 RESERKKERREREKRKREREKERK-RERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
Query: 303 TSDRRCSRSRDHKRSRSRERRRSRSRDR-RRSRSHDRSERKHRSRSRDRRRSKSRDRKSY 361
+RR + KR R + RR R + + R+ R + +R+ R R + R++ + ++RK
Sbjct: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150
Query: 362 KHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSE 421
K R K + + RK +E+EK+ ++K K R+++ E KE K E +
Sbjct: 151 KERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKE---RKK 207
Query: 422 DIKSEGDTQS 431
D K++ T S
Sbjct: 208 DRKTDRQTDS 217
Score = 112 bits (280), Expect = 7e-25
Identities = 57/192 (29%), Positives = 108/192 (56%), Gaps = 3/192 (1%)
Query: 226 TVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREE-RERKRRREEEEREKERA 284
T E + K +R E + ER K+ K+ER ++EK++ ++RE +ER+R+R+E E++++
Sbjct: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER 89
Query: 285 RDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHR 344
R++ERRKR + + + + RR + + ++ R RE ++ R R R++ R R + + R
Sbjct: 90 REKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKR 149
Query: 345 SRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTN 404
+ R +R K + RK + R K R+R + + KE+E++ ++K K R K+ E
Sbjct: 150 EKERGKRERKRKKRKK-EEREKKRERNRKERKKERERKERRERKKERKK-ERRKKKERKK 207
Query: 405 TESKESDTKNEV 416
+ T ++V
Sbjct: 208 DRKTDRQTDSQV 219
Score = 103 bits (256), Expect = 4e-22
Identities = 48/167 (28%), Positives = 99/167 (59%), Gaps = 1/167 (0%)
Query: 224 KATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKER 283
K E +K +K+ ++ +R + +++++ERE++ KER RE+E R+RK+ +++ ER++
Sbjct: 52 KERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER-REKERRKRKKEKKKRERKQRG 110
Query: 284 ARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKH 343
R+R+++K + R R + + +R+ + R KR + R+R + R + R+ + + ER+
Sbjct: 111 RRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREK 170
Query: 344 RSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSS 390
+ + R K R+RK + R K R +E+ +K + K+ R +D + S
Sbjct: 171 KRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDS 217
Score = 100 bits (249), Expect = 3e-21
Identities = 55/156 (35%), Positives = 93/156 (59%), Gaps = 5/156 (3%)
Query: 228 EELKEKLRKRTE-EPDRDERLKKEKQER--EEREKER-EREREERERKRRREEEEREKER 283
E KE+ RKR E E R ER +KE+++R E++++ER +R R ER++K+ R+E ERE ++
Sbjct: 70 ERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQ 129
Query: 284 ARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRR-RSRSHDRSERK 342
R+R+R+KR + + R + R R R K+ + ER + R R+R+ R + +R ER+
Sbjct: 130 RRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERR 189
Query: 343 HRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKE 378
R + R + R K ++RK + + D + R +E
Sbjct: 190 ERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRE 225
Score = 77.8 bits (190), Expect = 2e-14
Identities = 43/149 (28%), Positives = 80/149 (53%), Gaps = 20/149 (13%)
Query: 215 KQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRR 274
K+ K K E + R+R ++ +R ER ++ KQ RE + K+R +++ +ERKR +
Sbjct: 92 KERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREK 151
Query: 275 EEEEREKER-ARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRS 333
E +RE++R R +E R++ R R+R ++ K+ R R+ RR R ++R++
Sbjct: 152 ERGKRERKRKKRKKEEREKKRERNR-------------KERKKERERKERRERKKERKKE 198
Query: 334 RSHDRSERKHRSRSRDRRRSKSRDRKSYK 362
R RK + R +DR+ + D + ++
Sbjct: 199 R------RKKKERKKDRKTDRQTDSQVFR 221
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 118 bits (295), Expect = 1e-26
Identities = 73/209 (34%), Positives = 116/209 (55%), Gaps = 12/209 (5%)
Query: 228 EELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEE-EREKERARD 286
+E +E+ R + RDER ++ +ERE R++ERERERE RER R RE+E E E+ERAR+
Sbjct: 657 DERREERRVDRVDDRRDERARERDRERE-RDRERERERE-RERDREREKERELERERARE 714
Query: 287 RER-RKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRER---RRSRSRDRRRSRSHDRSERK 342
RER R++ R R R R DR R R+ R + RER R R R+R R R +R +
Sbjct: 715 REREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERER 774
Query: 343 HRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSED 402
R+R RD+ R + RD ++ + K RD ++++ + +E R D K S+++ +
Sbjct: 775 ERARERDKERERQRD---WEDKDKGRDDRREKREEIREDRNPRDGHDERK--SKKRYRNE 829
Query: 403 TNTESKESDTKNEVNGTSEDIKSEGDTQS 431
+ ++S + + D + GD ++
Sbjct: 830 GSPSPRQSPKRRREHSPDSDAYNSGDDKN 858
Score = 113 bits (283), Expect = 3e-25
Identities = 66/200 (33%), Positives = 108/200 (54%), Gaps = 24/200 (12%)
Query: 235 RKRTEEPDRDERL--------KKEKQEREEREKEREREREERERKRRREEEEREKERARD 286
R R + +RD+R + ++ ER+ER +ER +R + R R E +RE+ER R+
Sbjct: 629 RDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRE 688
Query: 287 RER-RKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRS------ 339
RER R+R R R R R +R +R R+ +R + R+R R R RD R R +R
Sbjct: 689 RERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKE 748
Query: 340 ---ERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEK-RGSDDKKSSVKSGS 395
ER+ R R R+R R + R+R+ + R++ RD+E++R+ ++K +G DD++
Sbjct: 749 REREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRRE-----K 803
Query: 396 REKQSEDTNTESKESDTKNE 415
RE+ ED N + K++
Sbjct: 804 REEIREDRNPRDGHDERKSK 823
Score = 110 bits (275), Expect = 2e-24
Identities = 73/202 (36%), Positives = 109/202 (53%), Gaps = 20/202 (9%)
Query: 227 VEELKEKLRKRTEEPDRDERLKKEKQEREEREKERERERE---ERERKRRRE-EEEREKE 282
V+ + ++ +R E DR+ +E++ ERE++RERE+E ERER R RE E E+E++
Sbjct: 665 VDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERD 724
Query: 283 RARDRER-----RKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHD 337
R RDR+R R+R R R R R +R R R+ +R R RER R R R+R R R +
Sbjct: 725 RERDRDRDHDRERERERERDREKERERERE-ERERERERERERERERERERERARERDKE 783
Query: 338 RSERK---HRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEK-EKRGSDDKKSSVKS 393
R ++ + + RD RR K R+ + RD +RKSK++ GS + S K
Sbjct: 784 RERQRDWEDKDKGRDDRREK---REEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPK- 839
Query: 394 GSREKQSEDTNTESKESDTKNE 415
R + S D++ + D KNE
Sbjct: 840 -RRREHSPDSDAYN-SGDDKNE 859
Score = 105 bits (262), Expect = 8e-23
Identities = 67/243 (27%), Positives = 115/243 (47%), Gaps = 23/243 (9%)
Query: 202 GDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRD---ERLKKEKQEREERE 258
G S++D H + + +++ E + + RD ER E+ R+ RE
Sbjct: 577 GSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRE 636
Query: 259 KER-------------EREREERERKRRREE-EEREKERARDRER---RKRSRSRSRHSS 301
+++ E ER+ER +RR + ++R ERAR+R+R R R R R R
Sbjct: 637 RDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERE 696
Query: 302 RTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKS- 360
R +R R + +R+R RER R + RDR R R D + R R RDR + + R+R+
Sbjct: 697 RDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREER 756
Query: 361 YKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKES--DTKNEVNG 418
+ R + R+RE++R+ + + R D ++ + + + D E +E + +N +G
Sbjct: 757 ERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDG 816
Query: 419 TSE 421
E
Sbjct: 817 HDE 819
Score = 101 bits (252), Expect = 1e-21
Identities = 57/195 (29%), Positives = 92/195 (47%), Gaps = 10/195 (5%)
Query: 237 RTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSR 296
R+ P+RD +++ ++ + R+ ER ER+R+ RE ++R R + R
Sbjct: 599 RSSYPERDRYPERDNRD-QARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERD 657
Query: 297 SRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSR 356
R R DR R + R R RER R R R+R R R DR K R R+R R + R
Sbjct: 658 ERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARERER 717
Query: 357 DRKSYKHRSKSRDREQDR---------KSKEKEKRGSDDKKSSVKSGSREKQSEDTNTES 407
+R+ + R + RDR+ DR + KE+E+ + ++ + RE++ E +
Sbjct: 718 EREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERA 777
Query: 408 KESDTKNEVNGTSED 422
+E D + E ED
Sbjct: 778 RERDKERERQRDWED 792
Score = 91.7 bits (226), Expect = 1e-18
Identities = 108/418 (25%), Positives = 173/418 (41%), Gaps = 67/418 (16%)
Query: 16 RNLAPDEKRSNVRWDHESVCKYYLCGFCPAELFTNTRSDLGPCEKIHDEN--------LR 67
RN + +E RS +R D + G P +R G H N R
Sbjct: 544 RNESRNESRSEIRNDRMGRSR----GRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETR 599
Query: 68 KQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGAAGPTGKNEE 127
Y + R+ ERD Q+ + ERR R ++Q+ S G+N+E
Sbjct: 600 SSYPERDRYP----ERD--NRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDE 653
Query: 128 ----------KIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLKEERELLRSTTS 177
++ + D+ D ++ + + E + + + ++EREL R
Sbjct: 654 LERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERAR 713
Query: 178 TIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKR 237
E +E+ E + R DH + E +E+ R++
Sbjct: 714 EREREREKERDRE--------------RDRDRDHDRER------------ERERERDREK 747
Query: 238 TEEPDRDERLKKEKQERE-EREKERERER-EERERKRRREEEEREKERARDRERRKRS-- 293
E +R+ER ++ ++ERE ERE+ERERER ER+++R R+ + +K++ RD R KR
Sbjct: 748 EREREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEI 807
Query: 294 ----RSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRD 349
R H R S +R +S +RRR S D S D KHR S+
Sbjct: 808 REDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQV 867
Query: 350 RRRSKSRDRKSYKHRSKSRD---REQDRKSKEKE-KRGSDDKKSSVKSGSREKQSEDT 403
R +SR S H ++ R +E+DRK + KE R ++++ K S +KQ E T
Sbjct: 868 VRPQESRS-LSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQT 924
Score = 72.8 bits (177), Expect = 6e-13
Identities = 60/235 (25%), Positives = 99/235 (42%), Gaps = 29/235 (12%)
Query: 200 IVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREK 259
I G+ +SR+D G+ ++ ++ + R P+ D ++ + R++
Sbjct: 1243 ITGERKSRIDQLKRGEP----SRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDR 1298
Query: 260 EREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRS 319
+ER+R E +R+R RE R +R R R +D+ R+RD R R
Sbjct: 1299 LQERDRYEHDRERERE----------------RRDTRQREWDRDADKDWPRNRD--RDRL 1340
Query: 320 RERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSR-------DREQ 372
RER R R RD+RR +R S RDR R + R +S + S R + E+
Sbjct: 1341 RERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHER 1400
Query: 373 DRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEG 427
D +S ++ D ++ GS + E +E ES + +D S G
Sbjct: 1401 DLESTSRDSLALDKERMDKDLGSVQGFEETNKSERTESLEAGDDESKLDDAHSLG 1455
Score = 72.4 bits (176), Expect = 7e-13
Identities = 39/160 (24%), Positives = 75/160 (46%)
Query: 271 KRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDR 330
+R R E +++ARD +R R R +R D+R S H+ R R +R
Sbjct: 604 ERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREER 663
Query: 331 RRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSS 390
R R DR + + R R R+R R + R+R+ + R + R++E++ + + +R + +K
Sbjct: 664 RVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKER 723
Query: 391 VKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEGDTQ 430
+ R++ + +E D + E E+ + E + +
Sbjct: 724 DRERDRDRDHDRERERERERDREKEREREREERERERERE 763
Score = 66.6 bits (161), Expect = 4e-11
Identities = 59/228 (25%), Positives = 92/228 (40%), Gaps = 20/228 (8%)
Query: 211 HLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERER 270
H G G ++ + +EK + +R R+ + K+ R +R+
Sbjct: 1215 HRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHS 1274
Query: 271 KRRREEEEREKERAR----DRERRKRSRSRSRHS-SRTSDRRCSRSRDHKRSRSRERRRS 325
RR E + +R D R + R R H R +RR +R R+ R ++ R+
Sbjct: 1275 SRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRN 1334
Query: 326 RSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSD 385
R RDR R + R R RD+RR R+R+ S RDR++DR + +
Sbjct: 1335 RDRDRL--R------ERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIES 1386
Query: 386 DKKSSVK-SGSREKQSEDTNTESKESDTK------NEVNGTSEDIKSE 426
K+ K G E+ E T+ +S D + V G E KSE
Sbjct: 1387 VKRCEAKLEGEHERDLESTSRDSLALDKERMDKDLGSVQGFEETNKSE 1434
Score = 64.3 bits (155), Expect = 2e-10
Identities = 57/195 (29%), Positives = 88/195 (45%), Gaps = 18/195 (9%)
Query: 235 RKRTEEPDRDERLKKEKQEREEREKERER--------EREERERKRRRE----EEEREKE 282
R+ D + +EK REERE E+++ +RE R+ + RR+ + RE
Sbjct: 412 RRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELR 471
Query: 283 RARDRERRKRSRSRSRHSSRTSDRRCSRS-RDHKRSRSRERRRSRSRD---RRRSRSHDR 338
+RD + R SR + + D R SRS RD R RE R + ++ SRS+ R
Sbjct: 472 DSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGR 531
Query: 339 SE-RKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKK-SSVKSGSR 396
+ R+ SR+ R S++ R ++ R R + + EK RGS + S S S
Sbjct: 532 NHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSN 591
Query: 397 EKQSEDTNTESKESD 411
S +T + E D
Sbjct: 592 YHDSWETRSSYPERD 606
Score = 62.8 bits (151), Expect = 6e-10
Identities = 50/184 (27%), Positives = 85/184 (46%), Gaps = 14/184 (7%)
Query: 236 KRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRS 295
+R + P R +EK + + +R R+ R + +REK+ RE R+ +
Sbjct: 383 QRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDS---REEREYEQD 439
Query: 296 RSRHSSRTSDRRCSRSRDHKRSR-SRERRRSR-SRDRRRSRSHDRSERKHRSRSRDRRRS 353
+S DR RD + +R +R+RR R SRD R S R+ R SRD + S
Sbjct: 440 QSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDS-------REMRDYSRDTKES 492
Query: 354 KS-RDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDT 412
+ RD +S + RDRE R + KE ++ +S ++ RE+ S +++
Sbjct: 493 RDPRDSRSTRDAHDYRDRE-GRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNES 551
Query: 413 KNEV 416
++E+
Sbjct: 552 RSEI 555
Score = 62.4 bits (150), Expect = 8e-10
Identities = 51/218 (23%), Positives = 91/218 (41%), Gaps = 34/218 (15%)
Query: 249 KEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSD--- 305
KEK + ++R +E+ R+ ++R R R+ E+R+K R+ + S SRH S +S
Sbjct: 281 KEKYKVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGS 340
Query: 306 --RRCSRSRDHKRS-------------------------RSRERRRSRSRDRRRSRSHDR 338
+R S S KR+ S +R++S R R R R
Sbjct: 341 SIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGR 400
Query: 339 SERKHRSRSRDRRRSKSRDRKSYKHRSKS----RDREQDRKSKEKEKRGSDDKKSSVKSG 394
+ + S+S DRR + D + + R K R+ EQD+ S + + + +
Sbjct: 401 HDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRD 460
Query: 395 SREKQSEDTNTESKESDTKNEVNGTSEDIKSEGDTQSN 432
+R+ + +S++ E+ S D K D + +
Sbjct: 461 ARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDS 498
Score = 61.6 bits (148), Expect = 1e-09
Identities = 53/190 (27%), Positives = 73/190 (38%), Gaps = 17/190 (8%)
Query: 243 RDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSR------ 296
RD K++ E R R REE R R E E +R RSR R
Sbjct: 513 RDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPE 572
Query: 297 -SRHSSRTS--DRRCSRSRDHK----RSRSRERRRSRSRDRRRSRSHDRSERKHRSRSR- 348
SR S D S S H RS ER R RD R ER+H R R
Sbjct: 573 KGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRR 632
Query: 349 DRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDK---KSSVKSGSREKQSEDTNT 405
D R R +H+ ++ + E+D + +E+ DD+ ++ + RE+ E
Sbjct: 633 DNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERE 692
Query: 406 ESKESDTKNE 415
+E D + E
Sbjct: 693 RERERDRERE 702
Score = 57.8 bits (138), Expect = 2e-08
Identities = 53/203 (26%), Positives = 88/203 (43%), Gaps = 22/203 (10%)
Query: 230 LKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRER 289
++EK R E + + E+ RE+ +R+RE++ RE + +++ ++ DRE
Sbjct: 395 MREKGRHDHERTSQSHDRRHER--REDTRGKRDREKDSREEREYEQDQSSSRDHRDDREP 452
Query: 290 RK-RSRSRSRHSSRTSDRRCSRS-RDHKRSRSRERRRSRSRDRRRSRS----HDRSERKH 343
R R R +R + + R SR RD + R R SRD R SRS HD +R+
Sbjct: 453 RDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREG 512
Query: 344 RSRSR------DRRRSKSRD-------RKSYKHRSKSRDREQDRKSKEKEKRGS-DDKKS 389
R R + RS R+ R ++ S++ R + R + RG +
Sbjct: 513 RDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPE 572
Query: 390 SVKSGSREKQSEDTNTESKESDT 412
GSR Q + ++ S D+
Sbjct: 573 KGSRGSRGSQIDSHSSNSNYHDS 595
Score = 55.5 bits (132), Expect = 9e-08
Identities = 58/248 (23%), Positives = 91/248 (36%), Gaps = 51/248 (20%)
Query: 231 KEKLRKRTEEPDRD--ERLKKEKQEREEREKER--------------------------- 261
K K++ R EE RD +R + +++RE+R+K R
Sbjct: 283 KYKVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSI 342
Query: 262 EREREERERKR--------------RREEEEREKERARDRERRK---RSRSRSRHSSRTS 304
+R RKR RR +R++ R RS R R
Sbjct: 343 QRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHD 402
Query: 305 DRRCSRSRDHKRSRSRERR--RSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYK 362
R S+S D + R + R R R +D R R +++ + R DR RDR+ +
Sbjct: 403 HERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDAR 462
Query: 363 H---RSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGT 419
R + RD R S+E D K+S SR + + + DT + +
Sbjct: 463 DTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTY 522
Query: 420 SEDIKSEG 427
E+ +S G
Sbjct: 523 PEESRSYG 530
Score = 55.1 bits (131), Expect = 1e-07
Identities = 50/213 (23%), Positives = 90/213 (42%), Gaps = 23/213 (10%)
Query: 224 KATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKERERE--REERERKRRREEEEREK 281
K + EE + + + + RD+R ++ ++R + R+R R+ R+ + RE + +
Sbjct: 428 KDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSR 487
Query: 282 ERARDRERRKRSRSRSRH---------SSRTSDRRCSRSRDHKRSRSRE---RRRSRSRD 329
+ R+ R +R H + R D SR + R+ RE R R+
Sbjct: 488 DTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNES 547
Query: 330 RRRSRSHDRSERKHRSRSR-------DRRRSKSRDRKSYKHRSKSRDREQDRKS-KEKEK 381
R SRS R++R RSR R R S+ S+ S D + R S E+++
Sbjct: 548 RNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDR 607
Query: 382 RGSDDKKSSVKSGSREKQ-SEDTNTESKESDTK 413
D + + S E++ E +++E D +
Sbjct: 608 YPERDNRDQARDSSFERRHGERDRRDNRERDQR 640
Score = 53.5 bits (127), Expect = 4e-07
Identities = 53/214 (24%), Positives = 95/214 (44%), Gaps = 31/214 (14%)
Query: 228 EELKEKLRKRTEEPDRDERLKKEKQEREE-REKERERE-REERERKRRREEEEREKERAR 285
E KE+ R+R E D+D+ +++REE RE R+ +ER+ K+R E R
Sbjct: 779 ERDKERERQRDWE-DKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQS 837
Query: 286 DRERRKRSRSRSRHSSRTSDR----------RCSRSRDHKRSRSRERRRSRSRDRRR--- 332
+ RR+ S ++S R SR S E R+ R ++ R
Sbjct: 838 PKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPE 897
Query: 333 ----SRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRS-------KSRDREQDRKSKEKEK 381
SR ++ E K + S D++R ++ +S + R+ +S DRE ++ ++ K
Sbjct: 898 RKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENK 957
Query: 382 RGSDDKKSSVKSGSREKQSEDTNTESKESDTKNE 415
+ + +K +K +K+ +D E +T +E
Sbjct: 958 KKAKIQKKPIK----KKKEDDVGIERGNIETTSE 987
Score = 49.7 bits (117), Expect = 5e-06
Identities = 53/218 (24%), Positives = 94/218 (43%), Gaps = 34/218 (15%)
Query: 231 KEKLRKRTEEPDRDERLKKEK--QEREEREKEREREREERERKRRREEEE-REKERARDR 287
K +L + P L ++R+ R KE +R+ E +E RR EE+E +EK + D+
Sbjct: 860 KHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDK 919
Query: 288 ERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRS 347
+R + S S R H +S RE R+HD +++K + +
Sbjct: 920 QREQTEILES------SRMRAQDIIGHHQSEDRETS---------DRAHDENKKKAKIQK 964
Query: 348 RDRRRSKSRD----RKSYKHRSK-----SRDREQDRKS---KEKEKRG----SDDKKSSV 391
+ ++ K D R + + S+ S + Q +KS K K+ +G SD++ +
Sbjct: 965 KPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQ 1024
Query: 392 KSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEGDT 429
R ++ T+ + + N NG ED + + DT
Sbjct: 1025 SKKKRGPRTPPITTKEELVEMCNGKNGILEDSQKKEDT 1062
Score = 49.7 bits (117), Expect = 5e-06
Identities = 52/205 (25%), Positives = 85/205 (41%), Gaps = 30/205 (14%)
Query: 235 RKRTEEPDRDERLKKEKQEREEREKERE------REREERERKRRREEEEREKERARD-- 286
R R E+ + ++ Q R+ +++R R R R R+ D
Sbjct: 1162 RTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQ 1221
Query: 287 --RERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHD------R 338
R+R S SR R +++ + R + + E RS S DR+ SRSH
Sbjct: 1222 SGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPE 1281
Query: 339 SERKHRSR-----SRDRRRSKSR---DRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSS 390
S+R+ SR SRDR + + R DR+ + R +R RE DR + + R D
Sbjct: 1282 SDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRD----- 1336
Query: 391 VKSGSREKQSEDTNTESKESDTKNE 415
+ RE++ E + ++ D + E
Sbjct: 1337 -RDRLRERERERERDKRRDLDRERE 1360
Score = 48.5 bits (114), Expect = 1e-05
Identities = 49/190 (25%), Positives = 81/190 (42%), Gaps = 21/190 (11%)
Query: 235 RKRTEEPDRD--ERLKKEKQEREEREKERERE------REERERKRRREEEERE--KERA 284
R+ E P D ER+K ++Q+ + ++R E R+E R R RE+E+ + KER
Sbjct: 75 RRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKERT 134
Query: 285 RDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKH- 343
+ E +R S D + D+ S E +R + + + E++
Sbjct: 135 PESEEENVEWETNRDDSDNGDI----NYDYVHELSLEMKRQKIQRELMKLEQENMEKREE 190
Query: 344 ----RSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQ 399
+ S + RSK S + SKS R+ KS K+ D K S+V S ++Q
Sbjct: 191 IIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKK--DRKTSAVSSPLLDQQ 248
Query: 400 SEDTNTESKE 409
+SK+
Sbjct: 249 RNSKTNQSKK 258
Score = 45.8 bits (107), Expect = 7e-05
Identities = 46/177 (25%), Positives = 71/177 (40%), Gaps = 40/177 (22%)
Query: 266 EERERKRRREEEEREK------ERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRS 319
E+ RK R E+ + E A+ R+ + RS S S+R++ RS +
Sbjct: 1154 EDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSN-----------RSHT 1202
Query: 320 RERRRSRSRDRRRSRSHDRSERKH--RSRSRDRRRSKSRD------------RKSYKHRS 365
R RS S D D+S RK S SRDR ++KS + ++ RS
Sbjct: 1203 SGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRS 1262
Query: 366 KSRDREQDRKSKEKEKRGSDDKKSSVKSGS---------REKQSEDTNTESKESDTK 413
S DR+ R + D++ +SGS R++ D E + DT+
Sbjct: 1263 TSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTR 1319
Score = 42.4 bits (98), Expect = 8e-04
Identities = 51/230 (22%), Positives = 96/230 (41%), Gaps = 38/230 (16%)
Query: 216 QHMGYAKIKATVEELKEKLRKRTE-EPDRDER---------LKKEKQEREEREKERERER 265
+H IK T E E + E E +RD+ + + E + ++ +RE +
Sbjct: 120 RHREKEDIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMK 179
Query: 266 EERERKRRREEEEREKERARDRERRKRSRSRS-RHSSRTSDRRCS--RSRDHKRSRSRER 322
E+E +REE +KE + + R K S S S R SS++ R+ S S K+ R
Sbjct: 180 LEQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSA 239
Query: 323 RRSRSRDRRRSRSHDRSER----------------------KHRSRSRDRRRSKSRDRKS 360
S D++R+ ++S++ K + + +DR K+RD K
Sbjct: 240 VSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKD 299
Query: 361 YKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKES 410
R + +R+++++ K + + S + S S+ ++ + S
Sbjct: 300 ---RGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHS 346
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 117 bits (293), Expect = 2e-26
Identities = 72/210 (34%), Positives = 108/210 (51%), Gaps = 13/210 (6%)
Query: 202 GDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKER 261
GD + R D + K + + E + K ++ DR+++ + E+ E++K R
Sbjct: 74 GDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGR 133
Query: 262 ERERE---ERERKRRREEE-EREKERARDRER-----RKRSRSRSRHSSRTSDRRCSRSR 312
ERER+ ERER R RE+E ER+ E+ RD +R R+R R R + R ++R R R
Sbjct: 134 ERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQR 193
Query: 313 DHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQ 372
D ++ R R+ R R R R+ R + R DRRR + RDR R K RDRE+
Sbjct: 194 DTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDR----DRGKERDRER 249
Query: 373 DRKSKEKEKRGSDDKKSSVKSGSREKQSED 402
DRK + K++R + KK + EK+ ED
Sbjct: 250 DRKEERKKERKKERKKERKEKKKEEKRRED 279
Score = 111 bits (278), Expect = 1e-24
Identities = 63/176 (35%), Positives = 98/176 (55%), Gaps = 17/176 (9%)
Query: 228 EELKEKLRKRTEEPDRDERLKKEKQEREEREKERERERE---ERERKRRREEE-----ER 279
E + + R++ E +RD +K+K ER++ RERER+ E+ER+R+ E++ E
Sbjct: 108 ETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRET 167
Query: 280 EKERARDRERRK-------RSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRR 332
E ER RDRER K R R R R + + +R+ R RD R R + R R DR
Sbjct: 168 ETERERDREREKQKERETERDRDRQRDTEKERERQTDRERD--RQRKTQTERQRETDREG 225
Query: 333 SRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKK 388
R DR + R R R + R + RDRK + + + ++R+++RK K+KE++ +DKK
Sbjct: 226 ERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKK 281
Score = 105 bits (263), Expect = 6e-23
Identities = 55/182 (30%), Positives = 100/182 (54%), Gaps = 6/182 (3%)
Query: 239 EEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRE---RRKRSRS 295
++ D D+R ++ + RE+ EKER+R+R +R+R+RRR+E+E + R R+++ R R R
Sbjct: 70 KDADGDDRQRERDRVREKTEKERDRDR-KRDRERRRKEKETNRNRDREKQTEIERDRERE 128
Query: 296 RSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKS 355
+ + R DR R RD R + RER+ + RD +R +R + R + ++R +
Sbjct: 129 KQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERD 188
Query: 356 RDRK--SYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTK 413
RDR+ + K R + DRE+DR+ K + +R + + + R ++ + KE D +
Sbjct: 189 RDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRE 248
Query: 414 NE 415
+
Sbjct: 249 RD 250
Score = 102 bits (253), Expect = 9e-22
Identities = 53/204 (25%), Positives = 105/204 (51%), Gaps = 11/204 (5%)
Query: 218 MGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEE 277
+G ++ T+ + R ++E R L + ++ + +++R ER+R R + E+
Sbjct: 36 LGTLWVEVTIPLDFSRGRLGSQESPRSWGLGQAHKDADGDDRQR-----ERDRVREKTEK 90
Query: 278 EREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHD 337
ER+++R RDRERR++ + +R+ R R R+ ++ + RER R R R+R R R +
Sbjct: 91 ERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDRE 150
Query: 338 RSERKHRSRSRD------RRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSV 391
+ + + RD R + R+R+ K R RDR++ R ++++ +R +D ++
Sbjct: 151 KERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQ 210
Query: 392 KSGSREKQSEDTNTESKESDTKNE 415
+ E+Q E +E+D + E
Sbjct: 211 RKTQTERQRETDREGERETDRRRE 234
Score = 97.1 bits (240), Expect = 3e-20
Identities = 48/135 (35%), Positives = 85/135 (62%), Gaps = 3/135 (2%)
Query: 231 KEKLRKRTEEPDRDERLKKEKQEREEREKERERERE-ERERKRRRE-EEEREKERARDRE 288
+EK R+R E DRD + + E + +RE+E+++ERE ER+R R+R+ E+ERE++ R+R+
Sbjct: 149 REKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERD 208
Query: 289 RRKRSRS-RSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRS 347
R++++++ R R + R +R R R+ +R R R + R R RDR+ R +R + + + R
Sbjct: 209 RQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERK 268
Query: 348 RDRRRSKSRDRKSYK 362
++ K R+ K K
Sbjct: 269 EKKKEEKRREDKKRK 283
Score = 84.3 bits (207), Expect = 2e-16
Identities = 45/133 (33%), Positives = 73/133 (54%), Gaps = 12/133 (9%)
Query: 228 EELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDR 287
E+ ++ R+ E +RD +K+K+ ER+++R+R+ E +E ER+ +R RDR
Sbjct: 158 EKDRDGQRETETERERDREREKQKERETERDRDRQRDTE--------KERERQTDRERDR 209
Query: 288 ERR---KRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDR-SERKH 343
+R+ +R R R R +DRR R RD R + R+R R R +R++ R +R ERK
Sbjct: 210 QRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKE 269
Query: 344 RSRSRDRRRSKSR 356
+ + RR K R
Sbjct: 270 KKKEEKRREDKKR 282
Score = 60.8 bits (146), Expect = 2e-09
Identities = 42/133 (31%), Positives = 68/133 (51%), Gaps = 19/133 (14%)
Query: 305 DRRCSRSR-DHKRSRSRERRRSRSRDRRR-----SRSHDRSERKHRSRSRDRRRSKSRDR 358
DR+ R R K + R+R R R R+RRR +R+ DR ++ R R+R + K R+R
Sbjct: 76 DRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRER 135
Query: 359 KSYKHRSKSRDREQDR-KSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVN 417
+ R + R+RE+DR + KE+E++ D + G RE ++E +E + E
Sbjct: 136 E----RDRGRERERDRDREKERERQTEKD-----RDGQRETETERERDREREKQKERE-- 184
Query: 418 GTSEDIKSEGDTQ 430
T D + DT+
Sbjct: 185 -TERDRDRQRDTE 196
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 112 bits (280), Expect = 7e-25
Identities = 81/251 (32%), Positives = 131/251 (52%), Gaps = 26/251 (10%)
Query: 205 QSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKERERE 264
+SR H K+ KIK E +KEK R++ E +++ +KE+ + ++R+KERE++
Sbjct: 366 KSRSRSHSRDKRKDTREKIKEK-ERVKEKDREKEREREKEREKEKERGKNKDRDKEREKD 424
Query: 265 REERERKRRREEEEREKERARDRERRK-RSRSRSRHSSRTSDRRCSRSRDHKRSRS---- 319
RE+ + K R E E+E E+ RD+E+ K + + + R R+ + R +D K+SR+
Sbjct: 425 REKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKD-KKSRTPPRS 483
Query: 320 -----RERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRS---KSRDRKSYKHRSKSRDRE 371
R R SR R RRRSRS RS R ++ R RS +SR++K K R K RD
Sbjct: 484 YNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKD-KKREKERDHI 542
Query: 372 QDRKSKEKE---KRGSDDK-------KSSVKSGSREKQSEDTNTESKESDTKNEVNGTSE 421
+R+ +E+ ++ S+D+ K+S +E E ++ SKE D K+
Sbjct: 543 SERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEEN 602
Query: 422 DIKSEGDTQSN 432
I+ G+ Q N
Sbjct: 603 KIQHNGNCQLN 613
Score = 104 bits (259), Expect = 2e-22
Identities = 64/208 (30%), Positives = 111/208 (53%), Gaps = 16/208 (7%)
Query: 224 KATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKER 283
+A +EL+E +++ +E Q E E + + R R K R
Sbjct: 269 QAAAKELEEVMKR-----------VREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSR 317
Query: 284 ARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRR--RSRSHDRSER 341
+ + +R RS+S+H SR+ +R SR +D +RS+S ++RS+SR+RR RSRSH R +R
Sbjct: 318 SSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKR 377
Query: 342 KH-RSRSRDRRRSKSRDRKSYKHRSKSRDREQDR-KSKEKEK-RGSDDKKSSVKSGSREK 398
K R + +++ R K +DR+ + R K R++E++R K+K+++K R D +K K RE+
Sbjct: 378 KDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERER 437
Query: 399 QSEDTNTESKESDTKNEVNGTSEDIKSE 426
+ E KE + + + E +S+
Sbjct: 438 EKEHEKDRDKEKEKEQDKEKEREKDRSK 465
Score = 102 bits (253), Expect = 9e-22
Identities = 60/230 (26%), Positives = 112/230 (48%), Gaps = 15/230 (6%)
Query: 203 DAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKERE 262
+ +S + G + + + K+ RKR++ R + R ++++
Sbjct: 294 EPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRS------RSHNRSRSRQKD 347
Query: 263 REREERERKRRREEEEREKERARD--RERRKRSRSRSRHSSRTS--DRRCSRSRDHKRSR 318
R R + K+R + ER K R+R R++RK +R + + R DR R R+ +R +
Sbjct: 348 RRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREK 407
Query: 319 SRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKE 378
+ER +++ RD+ R + ++ + K R R R++ K RD++ K + K ++RE+DR SKE
Sbjct: 408 EKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDR-SKE 466
Query: 379 KEKRGSDDKKSSVK----SGSREKQSEDTNTESKESDTKNEVNGTSEDIK 424
+++ DKKS + SR +S + S + + TS+ IK
Sbjct: 467 IDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIK 516
Score = 97.8 bits (242), Expect = 2e-20
Identities = 58/229 (25%), Positives = 107/229 (46%), Gaps = 29/229 (12%)
Query: 231 KEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERER---KRRREEEEREKERARDR 287
++K R+R++ P + +E+++ R R++ ++ RE+ K R +E++REKER R++
Sbjct: 344 RQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREK 403
Query: 288 ERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRS 347
ER K + R ++ R +R R +D ++ R RER + +DR + + ++ + K R +
Sbjct: 404 EREKE-KERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKD 462
Query: 348 RD------------------------RRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRG 383
R R RS SR+R+ + RS SR + K K R
Sbjct: 463 RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS 522
Query: 384 SDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEGDTQSN 432
+ + K REK+ D +E +E + + +S D + + N
Sbjct: 523 PSPRSRNKKDKKREKE-RDHISERRERERSTSMRKSSNDRDGKEKLEKN 570
Score = 87.4 bits (215), Expect = 2e-17
Identities = 46/192 (23%), Positives = 98/192 (51%), Gaps = 6/192 (3%)
Query: 231 KEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERR 290
K + R R + ++ K ++R K RER R+ R R R++ + +E+ +++ER
Sbjct: 332 KHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRER-RKSRSRSHSRDKRKDTREKIKEKERV 390
Query: 291 KRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDR 350
K + R + R +R + R + R +ER + R +D+ + R +R + + R +++
Sbjct: 391 KE-KDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEK 449
Query: 351 RRSKSRDRKSYKHRSKSRD--REQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESK 408
+ + ++++ K RSK D R++D+KS+ + + ++S +S SRE++ + + S+
Sbjct: 450 EKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRS--RSSSRERRRRRSRSSSR 507
Query: 409 ESDTKNEVNGTS 420
T + S
Sbjct: 508 SPRTSKTIKRKS 519
Score = 67.4 bits (163), Expect = 2e-11
Identities = 53/160 (33%), Positives = 76/160 (47%), Gaps = 19/160 (11%)
Query: 288 ERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRR--SRSHD---RSERK 342
E KR R S + +S + K RSR S +R + R S+SH RS+ K
Sbjct: 277 EVMKRVREAQSFISAAIEPESGKSNERKGGRSR----SHTRSKSRSSSKSHSRRKRSQSK 332
Query: 343 HRSRSRDRRRSKSRDRK----SYKHRSKSRDREQDR-----KSKEKEKRGSDDKKSSVKS 393
HRSRS +R RS+ +DR+ +K RSKSR+R + R + K K+ R +K VK
Sbjct: 333 HRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKE 392
Query: 394 GSREKQSEDTNTESKESDT-KNEVNGTSEDIKSEGDTQSN 432
REK+ E KE + KN+ + E D + +
Sbjct: 393 KDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKD 432
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 112 bits (280), Expect = 7e-25
Identities = 81/251 (32%), Positives = 131/251 (52%), Gaps = 26/251 (10%)
Query: 205 QSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKERERE 264
+SR H K+ KIK E +KEK R++ E +++ +KE+ + ++R+KERE++
Sbjct: 250 KSRSRSHSRDKRKDTREKIKEK-ERVKEKDREKEREREKEREKEKERGKNKDRDKEREKD 308
Query: 265 REERERKRRREEEEREKERARDRERRK-RSRSRSRHSSRTSDRRCSRSRDHKRSRS---- 319
RE+ + K R E E+E E+ RD+E+ K + + + R R+ + R +D K+SR+
Sbjct: 309 REKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKD-KKSRTPPRS 367
Query: 320 -----RERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRS---KSRDRKSYKHRSKSRDRE 371
R R SR R RRRSRS RS R ++ R RS +SR++K K R K RD
Sbjct: 368 YNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKD-KKREKERDHI 426
Query: 372 QDRKSKEKE---KRGSDDK-------KSSVKSGSREKQSEDTNTESKESDTKNEVNGTSE 421
+R+ +E+ ++ S+D+ K+S +E E ++ SKE D K+
Sbjct: 427 SERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEEN 486
Query: 422 DIKSEGDTQSN 432
I+ G+ Q N
Sbjct: 487 KIQHNGNCQLN 497
Score = 104 bits (259), Expect = 2e-22
Identities = 64/208 (30%), Positives = 111/208 (53%), Gaps = 16/208 (7%)
Query: 224 KATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKER 283
+A +EL+E +++ +E Q E E + + R R K R
Sbjct: 153 QAAAKELEEVMKR-----------VREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSR 201
Query: 284 ARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRR--RSRSHDRSER 341
+ + +R RS+S+H SR+ +R SR +D +RS+S ++RS+SR+RR RSRSH R +R
Sbjct: 202 SSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKR 261
Query: 342 KH-RSRSRDRRRSKSRDRKSYKHRSKSRDREQDR-KSKEKEK-RGSDDKKSSVKSGSREK 398
K R + +++ R K +DR+ + R K R++E++R K+K+++K R D +K K RE+
Sbjct: 262 KDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERER 321
Query: 399 QSEDTNTESKESDTKNEVNGTSEDIKSE 426
+ E KE + + + E +S+
Sbjct: 322 EKEHEKDRDKEKEKEQDKEKEREKDRSK 349
Score = 102 bits (253), Expect = 9e-22
Identities = 60/230 (26%), Positives = 112/230 (48%), Gaps = 15/230 (6%)
Query: 203 DAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKERE 262
+ +S + G + + + K+ RKR++ R + R ++++
Sbjct: 178 EPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRS------RSHNRSRSRQKD 231
Query: 263 REREERERKRRREEEEREKERARD--RERRKRSRSRSRHSSRTS--DRRCSRSRDHKRSR 318
R R + K+R + ER K R+R R++RK +R + + R DR R R+ +R +
Sbjct: 232 RRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREK 291
Query: 319 SRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKE 378
+ER +++ RD+ R + ++ + K R R R++ K RD++ K + K ++RE+DR SKE
Sbjct: 292 EKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDR-SKE 350
Query: 379 KEKRGSDDKKSSVK----SGSREKQSEDTNTESKESDTKNEVNGTSEDIK 424
+++ DKKS + SR +S + S + + TS+ IK
Sbjct: 351 IDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIK 400
Score = 97.8 bits (242), Expect = 2e-20
Identities = 58/229 (25%), Positives = 107/229 (46%), Gaps = 29/229 (12%)
Query: 231 KEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERER---KRRREEEEREKERARDR 287
++K R+R++ P + +E+++ R R++ ++ RE+ K R +E++REKER R++
Sbjct: 228 RQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREK 287
Query: 288 ERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRS 347
ER K + R ++ R +R R +D ++ R RER + +DR + + ++ + K R +
Sbjct: 288 EREKE-KERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKD 346
Query: 348 RD------------------------RRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRG 383
R R RS SR+R+ + RS SR + K K R
Sbjct: 347 RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS 406
Query: 384 SDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEGDTQSN 432
+ + K REK+ D +E +E + + +S D + + N
Sbjct: 407 PSPRSRNKKDKKREKE-RDHISERRERERSTSMRKSSNDRDGKEKLEKN 454
Score = 87.4 bits (215), Expect = 2e-17
Identities = 46/192 (23%), Positives = 98/192 (51%), Gaps = 6/192 (3%)
Query: 231 KEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERR 290
K + R R + ++ K ++R K RER R+ R R R++ + +E+ +++ER
Sbjct: 216 KHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRER-RKSRSRSHSRDKRKDTREKIKEKERV 274
Query: 291 KRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDR 350
K + R + R +R + R + R +ER + R +D+ + R +R + + R +++
Sbjct: 275 KE-KDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEK 333
Query: 351 RRSKSRDRKSYKHRSKSRD--REQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESK 408
+ + ++++ K RSK D R++D+KS+ + + ++S +S SRE++ + + S+
Sbjct: 334 EKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRS--RSSSRERRRRRSRSSSR 391
Query: 409 ESDTKNEVNGTS 420
T + S
Sbjct: 392 SPRTSKTIKRKS 403
Score = 67.4 bits (163), Expect = 2e-11
Identities = 53/160 (33%), Positives = 76/160 (47%), Gaps = 19/160 (11%)
Query: 288 ERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRR--SRSHD---RSERK 342
E KR R S + +S + K RSR S +R + R S+SH RS+ K
Sbjct: 161 EVMKRVREAQSFISAAIEPESGKSNERKGGRSR----SHTRSKSRSSSKSHSRRKRSQSK 216
Query: 343 HRSRSRDRRRSKSRDRK----SYKHRSKSRDREQDR-----KSKEKEKRGSDDKKSSVKS 393
HRSRS +R RS+ +DR+ +K RSKSR+R + R + K K+ R +K VK
Sbjct: 217 HRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKE 276
Query: 394 GSREKQSEDTNTESKESDT-KNEVNGTSEDIKSEGDTQSN 432
REK+ E KE + KN+ + E D + +
Sbjct: 277 KDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKD 316
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 110 bits (274), Expect = 3e-24
Identities = 82/248 (33%), Positives = 122/248 (49%), Gaps = 48/248 (19%)
Query: 219 GYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREE--------REKEREREREERER 270
G +I VE + + +R+ P R R + + E RE ERE+ER+ ER
Sbjct: 247 GAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLER 306
Query: 271 KRRREEEEREKERARDRE-RRKRSRSRSRHSSRTSDRRCSRSRDHK---RSRSRERRRSR 326
+ + E+ER + R+ DR R+RSRSR RH SR SRSRD K R R RER +
Sbjct: 307 EAKEREKERRRSRSIDRGLERRRSRSRERHRSR------SRSRDRKGDRRDRDREREKEN 360
Query: 327 SRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKS---------------YKHRSKSRDRE 371
R RRR R +D+ R + R+R R +S++++S +HR RD +
Sbjct: 361 ERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSK 420
Query: 372 QDRK-----SKEKEKRGSDDKKSSVK---SGSREKQSEDTNTESKESDTKNEVNGTSEDI 423
+++K S+E++ R +++ K S S+EK S+ N ESKE K +G
Sbjct: 421 KEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKN-ESKEKSNKRSRSG----- 474
Query: 424 KSEGDTQS 431
S+G T S
Sbjct: 475 -SQGRTDS 481
Score = 108 bits (270), Expect = 9e-24
Identities = 71/208 (34%), Positives = 105/208 (50%), Gaps = 24/208 (11%)
Query: 232 EKLRKRTEEPDRDE-RLKKEKQEREEREKEREREREERER------KRRREEEEREKERA 284
E+ R R+ E R R + K +R +R++ERE+E E R K R E E+E+ER+
Sbjct: 326 ERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERS 385
Query: 285 RDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHR 344
R+R + +RSR D+ R RD KR +E++ SRSR R ERKHR
Sbjct: 386 RERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSR---------ERKHR 436
Query: 345 SRSRDR---RRSKSRDR-KSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQS 400
SRSR R +RS+SR + KS KH+++S+++ R + R +KS + S K+
Sbjct: 437 SRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEK 496
Query: 401 EDTNTESKESDTKNEVNGTSEDIKSEGD 428
+ SKE K + D K + D
Sbjct: 497 SRKRSRSKERSHKRD----HSDSKDQSD 520
Score = 102 bits (253), Expect = 9e-22
Identities = 68/212 (32%), Positives = 108/212 (50%), Gaps = 12/212 (5%)
Query: 215 KQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKE--KQEREEREKEREREREERERKR 272
++H ++ + + +++ R+R +E +R R ++ K+ EREKERER RE + +R
Sbjct: 334 ERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQR 393
Query: 273 RREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRER---RRSRSRD 329
R E E +K + +RR R R + R SR R H RSRSR R +RSRSR
Sbjct: 394 SRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKH-RSRSRSRNAGKRSRSRS 452
Query: 330 RRRSRSH-----DRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRG- 383
+ +S H ++S ++ RS S+ R S + +K SK + R++ R + KR
Sbjct: 453 KEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDH 512
Query: 384 SDDKKSSVKSGSREKQSEDTNTESKESDTKNE 415
SD K S K R QS + ++ K+ K+E
Sbjct: 513 SDSKDQSDKHDRRRSQSIEQESQEKQHKNKDE 544
Score = 95.9 bits (237), Expect = 6e-20
Identities = 68/227 (29%), Positives = 108/227 (47%), Gaps = 23/227 (10%)
Query: 222 KIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRRE------ 275
+IK ++K+ ++ EE DR ++ + R R R R R RE
Sbjct: 232 QIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRS-PRRSRSRSHHREGHGSSS 290
Query: 276 ---EEEREKERAR---DRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRD 329
E EREKER R + + R++ R RSR R +RR SRSR+ RSRSR R R +
Sbjct: 291 FDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDR---KG 347
Query: 330 RRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSK-----EKEKRGS 384
RR R +R + R R RDR K R + K R +SR+R ++++S+ +K K
Sbjct: 348 DRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDK 407
Query: 385 DDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEGDTQS 431
DD++ + R+ + E ++ S+ + K+ S + ++S
Sbjct: 408 DDRRH--RDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRS 452
Score = 93.2 bits (230), Expect = 4e-19
Identities = 59/174 (33%), Positives = 90/174 (51%), Gaps = 6/174 (3%)
Query: 244 DERLKKEKQEREEREKEREREREER-ERKRRREEEEREKERARDRERRKRSRSRSRHSSR 302
D+++K ++ ++ KE E + ER+R R R R R RS R H S
Sbjct: 230 DQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSS 289
Query: 303 TSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYK 362
+ DR R ++ R R + R ++RRRSRS DR + RSRSR+R RS+SR R K
Sbjct: 290 SFDRELEREKE--RQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSR-DRK 346
Query: 363 HRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEV 416
+ RDRE++++++ +R D K + REK+ E + SKE ++ EV
Sbjct: 347 GDRRDRDREREKENERGRRRDRDYDKE--RGNEREKERERSRERSKEQRSRGEV 398
Score = 88.6 bits (218), Expect = 1e-17
Identities = 75/249 (30%), Positives = 113/249 (45%), Gaps = 24/249 (9%)
Query: 180 ESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEE-LKEKLRKRT 238
ESF E+ ++V G + +G+ L + + +I V++ + ++++ R
Sbjct: 179 ESFLDDEEDLDVKAGGGCVMTIGEMLRSFLTKLEWFSTL-FPRIPVPVQKNIDQQIKTRP 237
Query: 239 EEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRS---RS 295
+ +D KE E +R ER R R R R R + R+ RE S R
Sbjct: 238 RKIKKDG---KEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRE 294
Query: 296 RSRHSSRTSDRRCSRSRDHKRSRSR------ERRRSRSRDRRRSRSHDRSERKHRSRSRD 349
R R R ++ R+ +R RSR ERRRSRSR+R RSRS R +RK R RD
Sbjct: 295 LEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSR-DRKGDRRDRD 353
Query: 350 RRRSKS------RDRKSYKHRSKSRDREQDR---KSKEKEKRGSDDKKSSVKSGSREKQS 400
R R K RDR K R R++E++R +SKE+ RG ++K + +
Sbjct: 354 REREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHR 413
Query: 401 EDTNTESKE 409
+D KE
Sbjct: 414 DDKRDSKKE 422
Score = 48.1 bits (113), Expect = 2e-05
Identities = 36/154 (23%), Positives = 70/154 (45%), Gaps = 25/154 (16%)
Query: 203 DAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERL----KKEKQEREERE 258
D + DD K+ +++ ++ E K + R R+ + R K K + E +E
Sbjct: 408 DDRRHRDDKRDSKKEKKHSRSRS--RERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKE 465
Query: 259 KEREREREERERKRRREEEEREKERARDRER---RKRSRSRSRHSSRTSDRRCSRSRDHK 315
K +R R + + E+ +++E + +E+ R RS+ RS HK
Sbjct: 466 KSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERS----------------HK 509
Query: 316 RSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRD 349
R S + +S DRRRS+S ++ ++ + +++D
Sbjct: 510 RDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKD 543
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 109 bits (272), Expect = 6e-24
Identities = 65/186 (34%), Positives = 100/186 (53%), Gaps = 12/186 (6%)
Query: 229 ELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRE 288
E + K +R E + ER K+ K+ER ++EK+ ER++EERERK+RR REKE E
Sbjct: 56 ESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRR----REKENKEGEE 111
Query: 289 RRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDR-RRSRSHDRSERKHRSRS 347
+ KR + + RTS + R+ K R RE R+ R R + R + +R ERK R R
Sbjct: 112 KEKRKKKEKKERGRTSKE--GKERERKEERKREERKERERKKEEREKERERKERKKRERK 169
Query: 348 RDRRRSKSRDRKSYKHRSK----SRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDT 403
+ + + R K K R K ++R+++R+ KE+ +R + KK + R+K + T
Sbjct: 170 QVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQ-T 228
Query: 404 NTESKE 409
N KE
Sbjct: 229 NWREKE 234
Score = 107 bits (267), Expect = 2e-23
Identities = 57/197 (28%), Positives = 108/197 (54%), Gaps = 11/197 (5%)
Query: 224 KATVEELKEKLRKRTE-EPDRDERLKKEKQERE----EREKEREREREERERKRRREEEE 278
++ + E + ++ R E + +R+ KKE++ERE EREKER+RER ++E+K R++EE
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
Query: 279 REKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDR 338
RE+++ R R K ++ R + R R K + RER+ R R+ R+ R +
Sbjct: 95 RERKK---RRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKK 151
Query: 339 SERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREK 398
ER+ + R+R+ K R+RK + + R ++ ++ K++E+ + KK + RE+
Sbjct: 152 EERE---KERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRER 208
Query: 399 QSEDTNTESKESDTKNE 415
+ E E ++ + + +
Sbjct: 209 KKERKKKEERKKERQKD 225
Score = 100 bits (248), Expect = 3e-21
Identities = 61/208 (29%), Positives = 114/208 (54%), Gaps = 13/208 (6%)
Query: 201 VGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKE 260
+ + + ++ GK+ + K E K K R+R +E R+ K++K ER++ E+E
Sbjct: 38 IREREREIETRKEGKKERESERKKERREREKRK-REREKERKRERGKKEKKGERKKEERE 96
Query: 261 REREREERERKRRREEEEREKERARDRER-RKRSRSRSRHSSRTSDRRCSRSR-DHKRSR 318
R++ R E+E K E+E+R+K+ ++R R K + R R R + R R R +R +
Sbjct: 97 RKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREK 156
Query: 319 SRERRRSRSRDRRR-------SRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDRE 371
RER+ + R+R++ + +R ERK R R+R + R K R+RK + R K R ++
Sbjct: 157 ERERKERKKRERKQVGEKEEERKEKERKERKKRERNR-KERKKERERKERRERKKERKKK 215
Query: 372 QDRKSKEKEKRGSDDKKSSVKSGSREKQ 399
++RK + ++ R ++ ++ + G RE++
Sbjct: 216 EERKKERQKDRQTNWREK--ERGKRERK 241
Score = 96.7 bits (239), Expect = 4e-20
Identities = 58/177 (32%), Positives = 98/177 (55%), Gaps = 15/177 (8%)
Query: 228 EELKEKLRKRTEEPDRDERLKKEKQEREEREKERE-REREERERKRRREEEER------E 280
E KE+ R+R ++ + ER KKE++ER++R +E+E +E EE+E+++++E++ER
Sbjct: 72 EREKERKRERGKKEKKGER-KKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEG 130
Query: 281 KERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSR-----ERRRSRSRDRRRSRS 335
KER R ER++ R ++ R KR R + E R+ + R R+ R
Sbjct: 131 KERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRE 190
Query: 336 HDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVK 392
+R ERK + R R RR + ++RK + R K R +++ +EKE RG ++K K
Sbjct: 191 RNRKERK-KERERKERRERKKERKKKEERKKERQKDRQTNWREKE-RGKRERKERKK 245
Score = 85.1 bits (209), Expect = 1e-16
Identities = 62/217 (28%), Positives = 112/217 (51%), Gaps = 21/217 (9%)
Query: 147 GSEGKVEEAQGMMKLVEQLKEERELLRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQS 206
G + ++ E + ++ ++ K+ERE R +E++ E G G+ +
Sbjct: 33 GWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKK 92
Query: 207 RVDDHLMGKQHM----GYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREK--- 259
+ ++ G K K +E KE+ R E +R+ + +++++ER+ERE+
Sbjct: 93 EERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE 152
Query: 260 EREREREERERKRR-------REEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSR 312
ERE+ERE +ERK+R +EEE +EKER +ER+KR R+R + + +R+ R R
Sbjct: 153 EREKERERKERKKRERKQVGEKEEERKEKER---KERKKRERNR-KERKKERERKERRER 208
Query: 313 DHKRSRSRERRRSRSRDRR---RSRSHDRSERKHRSR 346
+R + ER++ R +DR+ R + + ERK R +
Sbjct: 209 KKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 81.3 bits (199), Expect = 2e-15
Identities = 46/170 (27%), Positives = 84/170 (49%), Gaps = 8/170 (4%)
Query: 261 REREREERERKRRREEEEREKERARDRERR---KRSRSRSRHSSRTSDRRCSRSRDHKRS 317
RERERE RK E ++E+E R +ERR KR R R + R ++ + K
Sbjct: 39 REREREIETRK----EGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
Query: 318 RSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSK 377
R R++RR ++ R +++ + R R + K R+RK + R + ++RE+ ++ +
Sbjct: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER 154
Query: 378 EKEKRGSDDKKSSVKS-GSREKQSEDTNTESKESDTKNEVNGTSEDIKSE 426
EKE+ + KK K G +E++ ++ + ++ +N E + E
Sbjct: 155 EKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKE 204
Score = 64.7 bits (156), Expect = 2e-10
Identities = 34/117 (29%), Positives = 60/117 (51%), Gaps = 2/117 (1%)
Query: 299 HSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDR 358
H S+ + +S +R R E R+ ++R R +R ER+ R R R++ R + R +
Sbjct: 24 HISKPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGK 83
Query: 359 KSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNE 415
K K K +RE+ ++ +EKE + ++K+ K +E+ T+ E KE + K E
Sbjct: 84 KEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGR--TSKEGKERERKEE 138
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 108 bits (269), Expect = 1e-23
Identities = 67/192 (34%), Positives = 101/192 (52%), Gaps = 11/192 (5%)
Query: 243 RDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSR 302
R+ R +++ R R R R +++ +R ++ R + R RDR RR+RSRSR + SR
Sbjct: 3 RESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDR-RRERSRSRDKRRSR 61
Query: 303 TSDR-RCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRS-------RSRDRRRSK 354
+ DR R RSR +R RSRERRRSRSRDRRRSRS R R S ++ +R RSK
Sbjct: 62 SRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSK 121
Query: 355 SRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKN 414
+ + K +D++ KEK+ D K + R+++ E E ++ +N
Sbjct: 122 EKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMEN 181
Query: 415 --EVNGTSEDIK 424
E+ E++K
Sbjct: 182 IGELKKEIEEMK 193
Score = 75.1 bits (183), Expect = 1e-13
Identities = 47/122 (38%), Positives = 64/122 (52%), Gaps = 2/122 (1%)
Query: 310 RSRDHKRSRSRERRRSRSRDRRRSRSHDRSER--KHRSRSRDRRRSKSRDRKSYKHRSKS 367
R H R RS R RS SR R RS S RS+R RSRSRDR R + R R K RS+S
Sbjct: 3 RESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRS 62
Query: 368 RDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEG 427
RDR++ R+S+ +E+ S +++ S R +S S+ S N+ T +S+
Sbjct: 63 RDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKE 122
Query: 428 DT 429
T
Sbjct: 123 KT 124
Score = 62.4 bits (150), Expect = 8e-10
Identities = 49/204 (24%), Positives = 93/204 (45%), Gaps = 18/204 (8%)
Query: 231 KEKLRKRTEEPD-RDERLKKEKQEREEREKEREREREERE---RKRRREEEEREKERARD 286
+++ R+R+ D R R + K+ R R +ER+R RE R R RRR R+R
Sbjct: 45 RDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRR-------SRSRS 97
Query: 287 RERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSR----SRDRRRSRSHDRSERK 342
R RR RS S S +T +R S+ + S+E+++ + + + + D+++ +
Sbjct: 98 RGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLE 157
Query: 343 HRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSED 402
R R R K R+ + K + +++ + ++ K+ S + + E + E
Sbjct: 158 EEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEG 217
Query: 403 TNTESKESDTKNEVNGTSEDIKSE 426
E +E D ++ E++K E
Sbjct: 218 NEMEGEELD---PLDAYMEEVKEE 238
>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
[Homo sapiens]
Length = 213
Score = 107 bits (268), Expect = 2e-23
Identities = 65/201 (32%), Positives = 108/201 (53%), Gaps = 12/201 (5%)
Query: 226 TVEELKEKLRKRTEEPDRD-ERLKKEKQEREEREKEREREREE-RERKRRREEE---ERE 280
T E ++ R+R E DR+ +R K+ K E E++R+R+RE RER R RE E +RE
Sbjct: 12 TETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDRE 71
Query: 281 KERARDRER---RKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHD 337
ER R+RER R+R R R R +DR R+ ++ + RE R R R+R + +
Sbjct: 72 GERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMG 131
Query: 338 RSERKHRSRSRDRRRSKSRDRKSYKHR---SKSRDREQDRKSKEKEKRGSDDKKSSVKSG 394
R + R R+R R R+R++ + R + R+RE++RK + + KR + +++
Sbjct: 132 RERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDM- 190
Query: 395 SREKQSEDTNTESKESDTKNE 415
RE+Q E ++ +++ E
Sbjct: 191 ERERQRETDRKRDRQRESERE 211
Score = 101 bits (251), Expect = 2e-21
Identities = 61/181 (33%), Positives = 100/181 (55%), Gaps = 5/181 (2%)
Query: 221 AKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRRE-EEER 279
AK T + E+ R+R E +R+ +E++++ +RE ER+RERE R+R R+RE E ER
Sbjct: 34 AKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERE-RDRDRQRETERER 92
Query: 280 EKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRS 339
+KER DR + R R + R +R R R+ ++ RER+ R DR R R +R
Sbjct: 93 DKERETDR-HTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERE 151
Query: 340 ERKHRSR-SRDRRRSKSRDRKSYKHRSK-SRDREQDRKSKEKEKRGSDDKKSSVKSGSRE 397
R R + DR R + R+RK + R + +++RE+ + + +R +D K+ + RE
Sbjct: 152 RETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERE 211
Query: 398 K 398
+
Sbjct: 212 R 212
Score = 99.0 bits (245), Expect = 7e-21
Identities = 51/186 (27%), Positives = 96/186 (51%), Gaps = 3/186 (1%)
Query: 245 ERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTS 304
E + ++++ R E ++ER+R +E + R E +R+++R R+RE R R R R + + R
Sbjct: 15 ETMDRQRERRRETDRERDRAKESKTEDRH-SERDRQRDRERNRE-RDRDREREKQTDREG 72
Query: 305 DRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHR 364
+R+ R RD R R ER R + R+ R DR +K + R +R R + R+++ R
Sbjct: 73 ERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGR 132
Query: 365 SKSRDREQDR-KSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDI 423
+ DRE DR + ++ E+ ++ + RE++ E ++ +TK T +
Sbjct: 133 ERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMER 192
Query: 424 KSEGDT 429
+ + +T
Sbjct: 193 ERQRET 198
Score = 97.8 bits (242), Expect = 2e-20
Identities = 57/192 (29%), Positives = 99/192 (51%), Gaps = 7/192 (3%)
Query: 240 EPDRDERLKKEKQEREEREKERERERE-ERERKRRREEEEREKERARDRER-RKRSRSRS 297
E + R + E +R++ER RE + ER+R + + E+R ER R R+R R R R R
Sbjct: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRD 61
Query: 298 RHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRD 357
R + +DR R R+ +R R R+R R RD+ R + R + ++R + RD
Sbjct: 62 REREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRD 121
Query: 358 RKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVN 417
R+ K + R+R+ DR++ + +R ++ ++ + RE+++ED + E +E + K E
Sbjct: 122 REREKQKEMGRERQTDRETDRERERQAERERET----GRERKTEDRHRE-RERERKRERE 176
Query: 418 GTSEDIKSEGDT 429
E + E T
Sbjct: 177 RKRETKERERHT 188
Score = 70.5 bits (171), Expect = 3e-12
Identities = 34/105 (32%), Positives = 62/105 (59%), Gaps = 3/105 (2%)
Query: 228 EELKEKLRKRTEEPDRDERLKKEKQEREEREKERERERE---ERERKRRREEEEREKERA 284
++ KE+ +R + +R+++ + ++ + +RE +RERER+ ERE R R+ E+R +ER
Sbjct: 109 QKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERE 168
Query: 285 RDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRD 329
R+R+R + + ++ R +D R R+ R R R+R R RD
Sbjct: 169 RERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
Score = 53.9 bits (128), Expect = 3e-07
Identities = 49/145 (33%), Positives = 72/145 (49%), Gaps = 31/145 (21%)
Query: 167 EERELLRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQ-HMGYAKIKA 225
+ERE R T + E +E++ME RV D KQ MG +
Sbjct: 94 KERETDRHTETDRERQKQKEREME----------------RVRDREREKQKEMGRER--- 134
Query: 226 TVEELKEKLRKRTEEPDRDERLKKEKQEREEREKERERERE-ERERKRRREEEER----E 280
+ +E R+R + +R+ +E++ E+R +ERERER+ ERERKR +E ER E
Sbjct: 135 --QTDRETDRERERQAERERETGRERKT-EDRHRERERERKRERERKRETKERERHTDME 191
Query: 281 KERARDRERRKRSRSRSRHSSRTSD 305
+ER R+ +R+ R R R S R D
Sbjct: 192 RERQRETDRK---RDRQRESERERD 213
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 107 bits (268), Expect = 2e-23
Identities = 73/206 (35%), Positives = 101/206 (49%), Gaps = 16/206 (7%)
Query: 222 KIKATVEELKEKLRKRTEEPDR----DERLKKEKQER---EEREKERERER--------E 266
K K+ E K + R R++E R D+ KK K E +E ++ RER +
Sbjct: 51 KRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGED 110
Query: 267 ERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSR 326
+RK R+ R R+R RERR RSRSR R SR+ R +SR R R + R RSR
Sbjct: 111 RHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSR 170
Query: 327 SRDRR-RSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSD 385
R RR RSRS RS +HR+RSR R RS+SRDRK + + R R RG +
Sbjct: 171 ERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRN 230
Query: 386 DKKSSVKSGSREKQSEDTNTESKESD 411
+ ++ +R + E +E +
Sbjct: 231 TAMDAQEALARRLERAKKLQEQREKE 256
Score = 104 bits (259), Expect = 2e-22
Identities = 64/166 (38%), Positives = 96/166 (57%), Gaps = 21/166 (12%)
Query: 235 RKRTEEPDRDERLKKEKQEREEREKE-REREREERERKRRREEEEREKERARDRERRKRS 293
R R+ E R + K R KE R E +++ K+ + EE +KE + D+ R + +
Sbjct: 44 RSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLN 103
Query: 294 RSRS---RHSSRTSDRRCSRSRDHKRSRSRERR-----------RSRSRDRRRSRSHDRS 339
S + RH + +R+ SR R H RSRSRERR RSRSR+R++SRS R
Sbjct: 104 SSENGEDRHKRK--ERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRE 161
Query: 340 ERKHRSRSRDRR---RSKSRDRKSYKHRSKSRDREQDRKSKEKEKR 382
+K RSRSR+R+ RS+SR R ++HR++SR R + R S++++KR
Sbjct: 162 RKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSR-SRDRKKR 206
Score = 100 bits (248), Expect = 3e-21
Identities = 66/207 (31%), Positives = 105/207 (50%), Gaps = 25/207 (12%)
Query: 219 GYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERER-------- 270
G A K + + K+K + R + + RE++R+ + E R+
Sbjct: 10 GLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKE 69
Query: 271 -----------KRRREEEEREKERARDRER-RKRSRSRSRHSSRTSDRRCSRSRDHKRSR 318
K+ + EE +KE + D+ R R S + +R+ SR R H RSR
Sbjct: 70 GRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSR 129
Query: 319 SRERR-RSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDR---KSYKHRSKSRDREQDR 374
SRERR RSRSR+R++SRS R +K RSRSR+R++S+SR R + + RS+SR R + R
Sbjct: 130 SRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHR 189
Query: 375 -KSKEKEKRGSDDKKSSVKSGSREKQS 400
+S+ + + S D+K ++ R +S
Sbjct: 190 TRSRSRTRSRSRDRKKRIEKPRRFSRS 216
Score = 86.3 bits (212), Expect = 5e-17
Identities = 59/204 (28%), Positives = 99/204 (48%), Gaps = 28/204 (13%)
Query: 240 EPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRE-----RRKRSR 294
+ +RD ++ +++KE+ + R + R R R+ R+ RSR
Sbjct: 5 DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSR 64
Query: 295 SRS----RHSSRTSDRRCSRSRDHK-------RSRSR--------ERRRSRSRDRRRSRS 335
SRS RH S+ + +S +H + R R +R + + R R RS
Sbjct: 65 SRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRS 124
Query: 336 HDRS---ERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVK 392
H RS ER+HRSRSR+R++S+SR R+ K RS+SR+R++ R S+ +E++ +S +
Sbjct: 125 HSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSR-SRSRERKRRIRSRSRSR 183
Query: 393 SGSREKQSEDTNTESKESDTKNEV 416
S R + + T S+ D K +
Sbjct: 184 SRHRHRTRSRSRTRSRSRDRKKRI 207
Score = 86.3 bits (212), Expect = 5e-17
Identities = 58/159 (36%), Positives = 86/159 (54%), Gaps = 12/159 (7%)
Query: 232 EKLRKRTEEPDRDERLKKEKQEREEREKEREREREE-----RERKRRREEE-EREKERAR 285
E KR E R + RE R + R RER++ RERK+ R ER+K R+R
Sbjct: 109 EDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSR 168
Query: 286 DRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSER---- 341
RER++R RSRSR SR+ R +RSR RSRSR+R++ + RR SRS R+
Sbjct: 169 SRERKRRIRSRSR--SRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPF 226
Query: 342 KHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKE 380
+ R+ + D + + +R + K + R++E K K++E
Sbjct: 227 RGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQE 265
Score = 37.7 bits (86), Expect = 0.020
Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 5/92 (5%)
Query: 345 SRSRDRRRSKSR----DRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQS 400
S RD+++ +S R S H S+SR R ++RK K + +S K G R +S
Sbjct: 17 SPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEG-RRHES 75
Query: 401 EDTNTESKESDTKNEVNGTSEDIKSEGDTQSN 432
+D +++ +S+ N+ +S+ + ++ N
Sbjct: 76 KDKSSKKHKSEEHNDKEHSSDKGRERLNSSEN 107
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 104 bits (260), Expect = 1e-22
Identities = 76/249 (30%), Positives = 126/249 (50%), Gaps = 29/249 (11%)
Query: 205 QSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREE-REKERER 263
+ R+ G+ H K K + K K ++R+ ++ ++L+ + E + + KE++R
Sbjct: 482 EKRMRSRSKGRDHEN-VKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDR 540
Query: 264 EREERER-------KRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKR 316
+ R R K RE+ R+RDR RR RSR+ R SR+ + R ++++R
Sbjct: 541 RAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRR 600
Query: 317 ---SRSRERR----RSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHR----- 364
SRSRERR RSRS+DRRR R RS + S+SR++ + ++++ KS HR
Sbjct: 601 RGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKS-SHRKENSE 659
Query: 365 ------SKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNG 418
SKSRD S+EK+ S +K S++ + + + ++KE D K +
Sbjct: 660 SEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKE-DEKIRSSV 718
Query: 419 TSEDIKSEG 427
E+ KS+G
Sbjct: 719 EKENQKSKG 727
Score = 102 bits (254), Expect = 7e-22
Identities = 86/261 (32%), Positives = 128/261 (49%), Gaps = 44/261 (16%)
Query: 203 DAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKERE 262
+ + +V DH + + ++ K K++KR + R + KEK + +ER+ +
Sbjct: 421 EKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSK--SKEKSKSKERDSKHN 478
Query: 263 REREERERKR---RREEEEREKERARDRERRKRSRSRSR--------------HS-SRTS 304
R E+R R R R E +EKE+ D + + + RSRS+ HS S+
Sbjct: 479 RNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEK 538
Query: 305 DRRC-SRSRD--------HKRSRSRERRRSRSRDRR-RSRSHD----RSERKHRSRS--- 347
DRR SRSR+ SR+RER RSR R RR RSR+HD RS+ HR R
Sbjct: 539 DRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEY 598
Query: 348 RDRRRSKSRDRKSYKHRSKSRD---REQDRKSKEKEKRGSDDK----KSSVKSGSREKQS 400
R R RS+SR+R++ RS+S+D R +D +S E+E+ S +K KS R++ S
Sbjct: 599 RRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENS 658
Query: 401 EDTNTESKESDTKNEVNGTSE 421
E +S N N + E
Sbjct: 659 ESEKRMYSKSRDHNSSNNSRE 679
Score = 95.1 bits (235), Expect = 1e-19
Identities = 74/219 (33%), Positives = 106/219 (48%), Gaps = 30/219 (13%)
Query: 231 KEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEE-----REKERAR 285
KEK R R + R+ + K K R +ER R R+ R R R + +E R R
Sbjct: 536 KEKDR-RAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYR 594
Query: 286 DRERRKRSRSRSRHS------SRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRS 339
++E R+R RSRSR SR+ DRR R R RS RE +SR++D+ R++ S
Sbjct: 595 EQEYRRRGRSRSRERRTPPGRSRSKDRR--RRRRDSRSSEREESQSRNKDKYRNQESKSS 652
Query: 340 ERKHRSRSRDRRRSKSRDRKSYKH-RSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREK 398
RK S S R SKSRD S + R K DR+Q SK K+ ++ KSS+ ++
Sbjct: 653 HRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDE 712
Query: 399 ------QSEDTNTESKESDTKNEVN---------GTSED 422
+ E+ ++ +E+D +E N GT ED
Sbjct: 713 KIRSSVEKENQKSKGQENDHVHEKNKKFDHESSPGTDED 751
Score = 83.6 bits (205), Expect = 3e-16
Identities = 70/256 (27%), Positives = 124/256 (48%), Gaps = 56/256 (21%)
Query: 224 KATVEELKEKLRKRTEEPDR---DERLKKE----KQEREEREKEREREREERERKRRREE 276
K+ + E+KE R +R D R E K E+E++ K+ + +ER+ +R E+
Sbjct: 385 KSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEK 444
Query: 277 EEREKERARDRERRKRSRSRSRHSSRTSDRRC---------------------------- 308
+++ K + + R + K SRS+S+ S++ +R
Sbjct: 445 DDKYKNKVKKRAKSK-SRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQ 503
Query: 309 --SRSRDHKRSRSRER-------------RRSRSRDRR---RSRSHDRSERKHRSRSRDR 350
S+ +D +RSRS+E+ +S+ +DRR RSR D ++ KH SR R
Sbjct: 504 SDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTR 563
Query: 351 RRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKES 410
RS+SRDR S + RS++ DR++ R SKE + + + +S SRE+++ + SK+
Sbjct: 564 ERSRSRDR-SRRVRSRTHDRDRSR-SKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDR 621
Query: 411 DTKNEVNGTSEDIKSE 426
+ + +SE +S+
Sbjct: 622 RRRRRDSRSSEREESQ 637
Score = 71.2 bits (173), Expect = 2e-12
Identities = 56/207 (27%), Positives = 101/207 (48%), Gaps = 21/207 (10%)
Query: 237 RTEEPDRDERLKKEKQEREEREKEREREREERER------KRRREEEEREKERARDRERR 290
R+ DR R + R+E ++ + ER E +E ++ R +ER+
Sbjct: 346 RSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERK 405
Query: 291 KRSRSRSRHSSRTSDRRCSRSRDHKRSRSRER---RRSRSRDRRRSRSHDRSERKHRSRS 347
S + + + +DHK S S+ER R S D+ +++ R++ K RS+S
Sbjct: 406 ITDHRNVSESPNRKNEKEKKVKDHK-SNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKS 464
Query: 348 RDRRRSKSRDRKSYKH---RSKSRDREQDRKS-KEKEK----RGSDDKKSSVKSGSRE-- 397
+++ +SK RD K ++ R +SR + +D ++ KEKEK +G D ++S K S++
Sbjct: 465 KEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLE 524
Query: 398 -KQSEDTNTESKESDTKNEVNGTSEDI 423
K +E +++SKE D + + DI
Sbjct: 525 SKSNEHDHSKSKEKDRRAQSRSRECDI 551
Score = 67.8 bits (164), Expect = 2e-11
Identities = 68/288 (23%), Positives = 125/288 (43%), Gaps = 66/288 (22%)
Query: 211 HLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERL---------------KKEKQERE 255
H K+ +K A+ E E L + + R E + K +++ER+
Sbjct: 241 HKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERK 300
Query: 256 EREKERERE------------------REERERKRRREEEEREKERARDRERRKRSRS-- 295
RE+ERERE R R+ K R R R+R R+R +RS +
Sbjct: 301 NRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPP 360
Query: 296 ----------RSRHSS-----RTSDRRCSRSRDHKRSRSRERRR--------SRSRDRRR 332
R R SS + + ++++RS R + R S S +R+
Sbjct: 361 HWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKN 420
Query: 333 SRSHDRSERKHRSRSRDRRRSKSRDRK---SYKHRSKSRDREQDR---KSKEKEKRGSDD 386
+ + K S+ RD RR+ +D K K R+KS+ R + + KSKE++ + + +
Sbjct: 421 EKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRN 480
Query: 387 KKSSVKSGSREKQSEDTNTESKESDT--KNEVNGTSEDIKSEGDTQSN 432
++ ++S S+ + E+ + K+SD+ K++ S++ + +++SN
Sbjct: 481 EEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSN 528
Score = 60.5 bits (145), Expect = 3e-09
Identities = 61/264 (23%), Positives = 106/264 (40%), Gaps = 73/264 (27%)
Query: 224 KATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRR---REEE--- 277
++ EE +K +K+ + R + +K+K+++ ++ E E E E + + R EE
Sbjct: 220 ESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPP 279
Query: 278 --------EREKERARDRERRKRSRSRSRHSSRTSD------RRCSRSRDHKRSRSRERR 323
+ +A ++ER+ R R R R + + RR +R ++ + R R
Sbjct: 280 IPENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPR 339
Query: 324 RSRSRDRRRSRSHDR--------------------------------------------- 338
R R+ R RSR R
Sbjct: 340 RYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPV 399
Query: 339 --SERK---HRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKS 393
ERK HR+ S R +++K H+S S++R+ R++ EK+ + + K KS
Sbjct: 400 RVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERD-IRRNSEKDDKYKNKVKKRAKS 458
Query: 394 GSREKQSEDTNTESKESDTKNEVN 417
SR K E ++SKE D+K+ N
Sbjct: 459 KSRSKSKE--KSKSKERDSKHNRN 480
Score = 54.3 bits (129), Expect = 2e-07
Identities = 48/207 (23%), Positives = 90/207 (43%), Gaps = 30/207 (14%)
Query: 248 KKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRH-----SSR 302
K +K++++ R+ R+ ++E+++RK+ ++ E E A + E + +S R +R
Sbjct: 226 KSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESE-AENLEAQPQSTVRPEEIPPIPENR 284
Query: 303 TSDRRCSRSRDHKRSRSRERRRSRSRD----------------RRRSRSHDRSERKHRSR 346
R+ D K ++RER R R + R + R R++R+
Sbjct: 285 FLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTP 344
Query: 347 SRDRRRSKSRDRKSYKHRSKSRDREQDRK--SKEKEKRGSDDKKSSVKSGSR------EK 398
SR R R + R ++ H + R Q + S E+ +G + + +K R E+
Sbjct: 345 SRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKER 404
Query: 399 QSEDTNTESKESDTKNEVNGTSEDIKS 425
+ D S+ + KNE +D KS
Sbjct: 405 KITDHRNVSESPNRKNEKEKKVKDHKS 431
Score = 48.9 bits (115), Expect = 9e-06
Identities = 34/157 (21%), Positives = 64/157 (40%), Gaps = 20/157 (12%)
Query: 287 RERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSR 346
+E +KR +S S SS +SD S S + + ++R + H ++ RKH+
Sbjct: 185 KEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKE 244
Query: 347 SRDRRRSKSRDRKSYKHRSKSRDRE----------------QDRKSKEKEKRGSDDKKSS 390
+ R++SK KS S++ + E ++R K +D+K+
Sbjct: 245 KKKRKKSK----KSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERK 300
Query: 391 VKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEG 427
+ RE++ N++ + V + IK G
Sbjct: 301 NRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRG 337
Score = 42.7 bits (99), Expect = 6e-04
Identities = 32/136 (23%), Positives = 55/136 (40%), Gaps = 6/136 (4%)
Query: 281 KERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSE 340
+E R+ E +K + S+ + C + + E++R +S S S D
Sbjct: 148 QEVVREIENQKTDAA-SKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDSDS 206
Query: 341 RKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQS 400
S D S+S + K R K + + KEK+KR K S KS S E ++
Sbjct: 207 SSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKR-----KKSKKSASSESEA 261
Query: 401 EDTNTESKESDTKNEV 416
E+ + + + E+
Sbjct: 262 ENLEAQPQSTVRPEEI 277
Score = 36.6 bits (83), Expect = 0.045
Identities = 24/124 (19%), Positives = 53/124 (42%), Gaps = 6/124 (4%)
Query: 235 RKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSR 294
R+ ++ ++D K QE + ++ E E+R + R+ R + +R +
Sbjct: 633 REESQSRNKD---KYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPF 689
Query: 295 SRSRHSSRTSDRRCS---RSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRR 351
S+ + SS+ ++ + S D K S E+ +S+ + H+++++ S
Sbjct: 690 SKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKKFDHESSPGTD 749
Query: 352 RSKS 355
KS
Sbjct: 750 EDKS 753
Score = 32.0 bits (71), Expect = 1.1
Identities = 18/121 (14%), Positives = 50/121 (41%), Gaps = 4/121 (3%)
Query: 231 KEKLRKRTEEPDRDERLK----KEKQEREEREKEREREREERERKRRREEEEREKERARD 286
+E+ + R ++ R++ K KE E E+R + R+ R ++ + + ++
Sbjct: 633 REESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKI 692
Query: 287 RERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSR 346
++ + + +S D + S + + +S+ + ++ + H+ S +
Sbjct: 693 KQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKKFDHESSPGTDEDK 752
Query: 347 S 347
S
Sbjct: 753 S 753
Score = 28.9 bits (63), Expect = 9.5
Identities = 19/80 (23%), Positives = 33/80 (41%), Gaps = 5/80 (6%)
Query: 352 RSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESD 411
+SK + + +H+S S S + S D +SS S E +E+ + + K+
Sbjct: 180 KSKVKKEEKKRHKSSS-----SSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKH 234
Query: 412 TKNEVNGTSEDIKSEGDTQS 431
KN E K + +S
Sbjct: 235 RKNSRKHKKEKKKRKKSKKS 254
>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
sapiens]
Length = 375
Score = 103 bits (257), Expect = 3e-22
Identities = 67/188 (35%), Positives = 95/188 (50%), Gaps = 10/188 (5%)
Query: 229 ELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRE 288
E K+K K+ + + +++ + RE R E + +RK R+ R R+R RE
Sbjct: 15 ESKDKSSKKHKSEEHNDKEHSSDKGRE-RLNSSENGEDRHKRKERKSSRGRSHSRSRSRE 73
Query: 289 RRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRR-----RSRSHDRSERKH 343
RR RSRSR R SR+ SR R RSRSRER++SRSR R RSRS RS +H
Sbjct: 74 RRHRSRSRERKKSRSR----SRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRH 129
Query: 344 RSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDT 403
R+RSR R RS+SRDRK + + R R RG + + ++ +R +
Sbjct: 130 RTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKK 189
Query: 404 NTESKESD 411
E +E +
Sbjct: 190 LQEQREKE 197
Score = 100 bits (250), Expect = 2e-21
Identities = 58/148 (39%), Positives = 92/148 (62%), Gaps = 10/148 (6%)
Query: 261 REREREERERKRRREEEEREKERARDRERRKRSRSRS---RHSSRTSDRRCSRSRDHKRS 317
R E +++ K+ + EE +KE + D+ R + + S + RH + +R+ SR R H RS
Sbjct: 12 RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRK--ERKSSRGRSHSRS 69
Query: 318 RSRERR-RSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDR---KSYKHRSKSRDREQD 373
RSRERR RSRSR+R++SRS R +K RSRSR+R++S+SR R + + RS+SR R +
Sbjct: 70 RSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRH 129
Query: 374 R-KSKEKEKRGSDDKKSSVKSGSREKQS 400
R +S+ + + S D+K ++ R +S
Sbjct: 130 RTRSRSRTRSRSRDRKKRIEKPRRFSRS 157
Score = 95.9 bits (237), Expect = 6e-20
Identities = 65/155 (41%), Positives = 91/155 (58%), Gaps = 11/155 (7%)
Query: 233 KLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRER-RK 291
K +R E D+ + K + +E ++E ++ RE E+ + KER R R
Sbjct: 9 KQGRRHESKDKSSK-KHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHS 67
Query: 292 RSRSRSR-HSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDR 350
RSRSR R H SR+ +R+ SRSR SR R++ RSRSR+R++SRS R ERK R RSR R
Sbjct: 68 RSRSRERRHRSRSRERKKSRSR----SRERKKSRSRSRERKKSRSRSR-ERKRRIRSRSR 122
Query: 351 RRSKSRDRKSYKHRSKSRDREQDRKSK-EKEKRGS 384
RS+ R R + RS++R R +DRK + EK +R S
Sbjct: 123 SRSRHRHRT--RSRSRTRSRSRDRKKRIEKPRRFS 155
Score = 91.3 bits (225), Expect = 2e-18
Identities = 60/151 (39%), Positives = 87/151 (57%), Gaps = 13/151 (8%)
Query: 234 LRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRS 293
L++ +D+ KK K E E +KE ++ E+R K R+ RK S
Sbjct: 8 LKQGRRHESKDKSSKKHKSE-EHNDKEHSSDKGRERLNSSENGEDRHK-----RKERKSS 61
Query: 294 RSRSRHSSRTSDRRC-SRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRR- 351
R RS SR+ +RR SRSR+ K+SRSR SR R + RSRS +R + + RSR R RR
Sbjct: 62 RGRSHSRSRSRERRHRSRSRERKKSRSR----SRERKKSRSRSRERKKSRSRSRERKRRI 117
Query: 352 RSKSRDRKSYKHRSKSRDREQDRKSKEKEKR 382
RS+SR R ++HR++SR R + R S++++KR
Sbjct: 118 RSRSRSRSRHRHRTRSRSRTRSR-SRDRKKR 147
Score = 86.3 bits (212), Expect = 5e-17
Identities = 58/159 (36%), Positives = 86/159 (54%), Gaps = 12/159 (7%)
Query: 232 EKLRKRTEEPDRDERLKKEKQEREEREKEREREREE-----RERKRRREEE-EREKERAR 285
E KR E R + RE R + R RER++ RERK+ R ER+K R+R
Sbjct: 50 EDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSR 109
Query: 286 DRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSER---- 341
RER++R RSRSR SR+ R +RSR RSRSR+R++ + RR SRS R+
Sbjct: 110 SRERKRRIRSRSR--SRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPF 167
Query: 342 KHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKE 380
+ R+ + D + + +R + K + R++E K K++E
Sbjct: 168 RGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQE 206
Score = 59.7 bits (143), Expect = 5e-09
Identities = 36/126 (28%), Positives = 63/126 (50%), Gaps = 9/126 (7%)
Query: 289 RRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSR 348
RR S+ +S ++ + ++H + RER S R + +R + RS SR
Sbjct: 12 RRHESKDKSSKKHKSEEHN---DKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68
Query: 349 DR---RRSKSRDRKSYKHRSKSRDREQDR---KSKEKEKRGSDDKKSSVKSGSREKQSED 402
R RR +SR R+ K RS+SR+R++ R + ++K + S ++K ++S SR +
Sbjct: 69 SRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHR 128
Query: 403 TNTESK 408
T S+
Sbjct: 129 HRTRSR 134
Score = 42.7 bits (99), Expect = 6e-04
Identities = 29/110 (26%), Positives = 50/110 (45%), Gaps = 20/110 (18%)
Query: 331 RRSRSHDRSERKHRS-----------RSRDR--------RRSKSRDRKSYKHRSKSRDRE 371
RR S D+S +KH+S + R+R R K ++RKS + RS SR R
Sbjct: 12 RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS 71
Query: 372 QDRKSKEKEK-RGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTS 420
++R+ + + + R +S + SR + E + S+ + K + S
Sbjct: 72 RERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRS 121
>gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]
Length = 285
Score = 102 bits (255), Expect = 5e-22
Identities = 61/179 (34%), Positives = 95/179 (53%), Gaps = 21/179 (11%)
Query: 231 KEKLRKRTEEPDRDERLKKEKQEREEREKERERER-EERERKRRR---------EEEERE 280
+E+ RKR +E R++ + EK +R+++RER+R +R+RKR R E + E
Sbjct: 66 RERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEE 125
Query: 281 KERARDRERRK-RSRSRSRHSSRTSDRRCSRSRDHKRSRS---------RERRRSRSRDR 330
+ER RDR+R K R R R R DR +D R R RER R + R+
Sbjct: 126 RERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRET 185
Query: 331 RRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKS 389
RR R +R +R+ R RDR R K R++ Y+ R RDR+++R + + ++ D +K+
Sbjct: 186 RRDRDRER-QREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQKA 243
Score = 100 bits (250), Expect = 2e-21
Identities = 60/203 (29%), Positives = 99/203 (48%), Gaps = 21/203 (10%)
Query: 233 KLRKRTEEPDRD----------ERLKKEKQEREEREKEREREREERERKRRREEEEREKE 282
+L R++ DRD + +E++ + ERE++R+R +E K R E++R+++
Sbjct: 32 RLAMRSQIEDRDVLILRGSRVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQ 91
Query: 283 RARDRER---RKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRS 339
R RDRER R R R R R R + R + +R R R+R + R R R+R D+
Sbjct: 92 RKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKD 151
Query: 340 ERKHRSRSRDRRRS-------KSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVK 392
+ RDR R + R+R+ K R RDR+++R+ +EKE R D + +
Sbjct: 152 REIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQ-REKEDRERDRDRQKER 210
Query: 393 SGSREKQSEDTNTESKESDTKNE 415
R ++ E KE D + +
Sbjct: 211 EKDRYRERETGRDRDKERDRERQ 233
Score = 95.5 bits (236), Expect = 8e-20
Identities = 62/188 (32%), Positives = 97/188 (51%), Gaps = 19/188 (10%)
Query: 242 DRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRER-RKRSRSRSRHS 300
+R+ + ++E+Q + +E+ RE++RE + + R+ + +RE++R RDR+R R+R R R +
Sbjct: 59 ERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRET 118
Query: 301 SRTSDRRCSRSRDHKRSRSRERRRSRS------------RDRRRSRSHDRSER-KHRSRS 347
R RD KR + RER+R R +DR R R +ER + R R
Sbjct: 119 ETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERE 178
Query: 348 RDRRRSKSRDRKSYKHRSKSRDREQDR-KSKEKEK---RGSDDKKSSVKSGSREKQSEDT 403
R ++R RDR + R K DRE+DR + KE+EK R + + K RE+Q E
Sbjct: 179 RQKQRETRRDRDRERQREKE-DRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKD 237
Query: 404 NTESKESD 411
K D
Sbjct: 238 RDRQKAID 245
Score = 77.0 bits (188), Expect = 3e-14
Identities = 45/121 (37%), Positives = 69/121 (57%), Gaps = 15/121 (12%)
Query: 228 EELKEKLRKRTEEPDRDERLKKE----KQEREEREKERERERE--------ERERKRRRE 275
+E +E+ R R E DR+ + ++E K E EK+R+RERE +RER+R+++
Sbjct: 123 QEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQ 182
Query: 276 EE-EREKERARDRERRKRSRSRSRHSSRTSDRRCSRS--RDHKRSRSRERRRSRSRDRRR 332
E R+++R R RE+ R R R R R DR R RD + R RER+R + RDR++
Sbjct: 183 RETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQK 242
Query: 333 S 333
+
Sbjct: 243 A 243
Score = 71.2 bits (173), Expect = 2e-12
Identities = 50/165 (30%), Positives = 73/165 (44%), Gaps = 30/165 (18%)
Query: 279 REKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDR 338
RE+ER R+RER+ R R++ RH R DR + RD R R RDR R R DR
Sbjct: 58 RERERQRERERQ-RKRAKERH--REKDREIEKDRD----------RQRKRDRERQRWRDR 104
Query: 339 SERKHRSRSRDR--------RRSKSRDRKSYKHRSKSRDRE---------QDRKSKEKEK 381
++ R RDR R + RDRK K R + R RE + K +++E+
Sbjct: 105 DRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDRER 164
Query: 382 RGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSE 426
+ ++ + R+KQ E +E + E D + E
Sbjct: 165 EMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKE 209
Score = 53.1 bits (126), Expect = 5e-07
Identities = 30/80 (37%), Positives = 54/80 (67%), Gaps = 3/80 (3%)
Query: 215 KQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQERE-EREKERERER-EERERKR 272
++ MG + E ++K R+ + DR+ + +KE +ER+ +R+KERE++R ERE R
Sbjct: 163 EREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGR 222
Query: 273 RREEE-EREKERARDRERRK 291
R++E +RE++R +DR+R+K
Sbjct: 223 DRDKERDRERQREKDRDRQK 242
Score = 41.6 bits (96), Expect = 0.001
Identities = 21/69 (30%), Positives = 42/69 (60%), Gaps = 13/69 (18%)
Query: 231 KEKLRKRTEEPDRDERLKKEKQERE---EREKERE----------REREERERKRRREEE 277
+E+ ++R DRD ++EK++RE +R+KERE R+R++ + R+ E+
Sbjct: 177 RERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREK 236
Query: 278 EREKERARD 286
+R++++A D
Sbjct: 237 DRDRQKAID 245
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 102 bits (254), Expect = 7e-22
Identities = 75/231 (32%), Positives = 110/231 (47%), Gaps = 10/231 (4%)
Query: 203 DAQSRVDDHLMGKQHMGYAKIKATVE-ELKEKLRKRTEEPDRDERLKKEKQEREEREKER 261
D S+ + M + + I A +E + KE+ R+ + R R + R R + R
Sbjct: 213 DTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSR 272
Query: 262 EREREERERKRRREEEEREKERARDRERRKRSRSRSR-HSSRTSDRRCSRSRDHKRSRS- 319
R R + + RR + + R+ RER +RSRS S+ + D+ RS+ +S S
Sbjct: 273 SRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYST 332
Query: 320 --RERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSK 377
R R SR R RRRSRS RS +K RS R RS S R + K +D++++R
Sbjct: 333 ARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHK---KEKKKDKDKERSRD 389
Query: 378 EKEKRGSDDKKSSVKSGSREKQSE-DTNTESKESDTKNEVNG-TSEDIKSE 426
E+E+ S KKS K RE++SE D + + D E G SE K E
Sbjct: 390 ERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKE 440
Score = 94.7 bits (234), Expect = 1e-19
Identities = 71/221 (32%), Positives = 105/221 (47%), Gaps = 30/221 (13%)
Query: 234 LRKRTEEPDRDERLKK--EKQEREEREKEREREREERERKRRREEEEREKERARDRERRK 291
L+ T + +E +K+ E Q E +++ E+R R R R + + R RR
Sbjct: 210 LKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRS 269
Query: 292 RSRSRSRHSSRTSDRRCSRSRDHKRSRSRER-RRSRSRDR-------------------- 330
RSRSR R S++ RR S+S +RS SRER RRSRS +
Sbjct: 270 RSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKS 329
Query: 331 ----RRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDD 386
RRSRS R R+ RSRS R K R K RS S R + K K+K+K S D
Sbjct: 330 YSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRD 389
Query: 387 KKSSVKSGSREKQSEDTNTE-SKESDTKNEVNGTSEDIKSE 426
++ +S S++K+S+D + ++S++ +V + D E
Sbjct: 390 ERE--RSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEE 428
Score = 87.4 bits (215), Expect = 2e-17
Identities = 64/246 (26%), Positives = 108/246 (43%), Gaps = 23/246 (9%)
Query: 172 LRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELK 231
L+S TS+ E A ++ E + A I D + H + + ++ +
Sbjct: 210 LKSDTSSKEIEEAMKRVREAQSLISA-AIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRR 268
Query: 232 EKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRE--- 288
+ R R + ++ K R R RER R R + R++++ +KE+ R +
Sbjct: 269 SRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPK 328
Query: 289 -----RRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKH 343
RR RS SR R R+ S +R K+ RS +R+ SRS RR +K
Sbjct: 329 SYSTARRSRSASRERRRRRSR----SGTRSPKKPRSPKRKLSRSPSPRR-------HKKE 377
Query: 344 RSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDT 403
+ + +D+ RS+ +S + KS+D+E+DR E++ D K + E+Q D+
Sbjct: 378 KKKDKDKERSRDERERSTSKKKKSKDKEKDR---ERKSESDKDVKQVTRDYDEEEQGYDS 434
Query: 404 NTESKE 409
E KE
Sbjct: 435 EKEKKE 440
Score = 72.0 bits (175), Expect = 1e-12
Identities = 51/205 (24%), Positives = 98/205 (47%), Gaps = 37/205 (18%)
Query: 231 KEKLRKRTEEPDRDERLKKEKQEREEREKEREREREER--------------ERKRRREE 276
K R+R+ +R R + + R+++++++E++R + R+RRR
Sbjct: 288 KSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRR-- 345
Query: 277 EEREKERARDRERRKRSRSRSRHSSRTSDRRCSRS---RDHKRSRSRERRRSRSRDRRRS 333
RR RS +RS R+ R+ SRS R HK+ + +++ + RSRD R
Sbjct: 346 ------------RRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERER 393
Query: 334 RSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKS 393
+ + + K + + R+R KS K K ++ D E+ EKEK+ ++K +++
Sbjct: 394 STSKKKKSKDKEKDRER---KSESDKDVKQVTRDYDEEEQGYDSEKEKK---EEKKPIET 447
Query: 394 GSREKQSEDTNTESKESDTKNEVNG 418
GS + + + +S +++VNG
Sbjct: 448 GSPKTKECSVEKGTGDSLRESKVNG 472
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 101 bits (252), Expect = 1e-21
Identities = 65/199 (32%), Positives = 103/199 (51%), Gaps = 9/199 (4%)
Query: 231 KEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERR 290
+ K R R++ R KKEK +EK R R + + + +++ EK + D +
Sbjct: 229 RSKSRSRSQSRSRS---KKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGK 285
Query: 291 KRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDR 350
+SRS SRH S++ R S+ R + + R RS+++ +S RS K SRSR R
Sbjct: 286 PKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSR 345
Query: 351 RRSKSRDRKSYKHRSKSRDREQDR---KSKEKEKRGSDDKKSSVKSGSREKQSEDTNTES 407
RSKS+D++ + RS+ R + R KS+ KRGS K+ S S++K+ EDT+
Sbjct: 346 SRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGS--KRDSKAGSSKKKKKEDTDRSQ 403
Query: 408 KESDTKNEVNGTSEDIKSE 426
S +++ V+ E KSE
Sbjct: 404 SRSPSRS-VSKEREHAKSE 421
Score = 89.4 bits (220), Expect = 6e-18
Identities = 67/212 (31%), Positives = 107/212 (50%), Gaps = 18/212 (8%)
Query: 231 KEKLRKRTEEP-DRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRE- 288
+ K + + EE ++ + K K R K + + R + +R EE+ R R +E
Sbjct: 266 RSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEK 325
Query: 289 --RRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSR 346
R+ RSRSRS+ SR+ R S+S+D ++ R R R SRSR R RS +SER +
Sbjct: 326 SLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRS----KSERSRKRG 381
Query: 347 SRDRRRSKSRDRKSYKHRSKSRDREQDRK-SKEKEKRGSDDKKSSVKSGSREKQSEDTNT 405
S+ ++ S +K + +S+ R R SKE+E S+ SS + G E ++ TN
Sbjct: 382 SKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSE---SSQREGRGESENAGTNQ 438
Query: 406 ESK---ESDTKNEVNGTSED---IKSEGDTQS 431
E++ S++K++ N SE KS T+S
Sbjct: 439 ETRSRSRSNSKSKPNLPSESRSRSKSASKTRS 470
Score = 88.6 bits (218), Expect = 1e-17
Identities = 62/209 (29%), Positives = 97/209 (46%), Gaps = 8/209 (3%)
Query: 205 QSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKERERE 264
+SR H GK +K K EE + + R K K + R +ER E
Sbjct: 254 KSRSRSHSAGKSR---SKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVE 310
Query: 265 REERERKRRREEEEREKERARDRERRKR-SRSRSRHSSRTSDRRCSRSRDHKRSRSRERR 323
E+R R +E+ ++R R R K SRSRSR S++ D+R R R + SRSR R
Sbjct: 311 EEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRS 370
Query: 324 RSRS-RDRRRSRSHDR---SERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEK 379
RS+S R R+R D S +K + DR +S+S R K R ++ R+ + +
Sbjct: 371 RSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGE 430
Query: 380 EKRGSDDKKSSVKSGSREKQSEDTNTESK 408
+ ++++ +S S K + +ES+
Sbjct: 431 SENAGTNQETRSRSRSNSKSKPNLPSESR 459
Score = 83.6 bits (205), Expect = 3e-16
Identities = 57/154 (37%), Positives = 82/154 (53%), Gaps = 10/154 (6%)
Query: 271 KRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRS----RDHKRSRSRERRRSR 326
++ R E++ R R R RS SRSR SR S + SRS H +SRSR R SR
Sbjct: 168 RKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSR 227
Query: 327 SRDRRRSRSHDRS-ERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSD 385
SR + RSRS RS +K +SRS + +S+SR + K RSKS+D +++EK + +
Sbjct: 228 SRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKD-----QAEEKIQNNDN 282
Query: 386 DKKSSVKSGSREKQSEDTNTESKESDTKNEVNGT 419
K +S SR K + + S+E + E G+
Sbjct: 283 VGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGS 316
Score = 80.5 bits (197), Expect = 3e-15
Identities = 66/265 (24%), Positives = 114/265 (43%), Gaps = 49/265 (18%)
Query: 216 QHMGYAKIKATVEELK------EKLRKRTEEPDRDERLKKEKQEREEREKEREREREERE 269
+ + Y+ +K +E+L K+R ++P R + R + R R +
Sbjct: 146 EFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSR 205
Query: 270 RKRRREEEEREKERARDRE-RRKRSRSRSRHSSRT-SDRRCSRSRDHKRSRSRE----RR 323
+ + K R+R R R RS+SRSR SR+ S + SRS ++SRSR +
Sbjct: 206 SRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKS 265
Query: 324 RSRSRD---------------RRRSRSHDRSERKHRSRSRDRR----------------- 351
RS+S+D + RS S +S+ K RSRS++RR
Sbjct: 266 RSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEK 325
Query: 352 -----RSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTE 406
RS+SR + + RS+SR + +D++ K R +S +S S + + +
Sbjct: 326 SLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRD 385
Query: 407 SKESDTKNEVNGTSEDIKSEGDTQS 431
SK +K + ++ +S ++S
Sbjct: 386 SKAGSSKKKKKEDTDRSQSRSPSRS 410
Score = 78.2 bits (191), Expect = 1e-14
Identities = 58/208 (27%), Positives = 91/208 (43%), Gaps = 13/208 (6%)
Query: 201 VGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKE 260
VG +SR K + VEE K R ++ R + + + +
Sbjct: 283 VGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRS 342
Query: 261 REREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSR---DHKRS 317
R R R + + KR+ + RE+ R+R R R K RSR R S R S S+ + D RS
Sbjct: 343 RSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRS 402
Query: 318 RSRERRRSRSRDRRRSRSHDRSERKHRSRS---------RDRRRSKSRDRKSYKHRSKSR 368
+SR RS S++R ++S + S+R+ R S R R RS S+ + + S+SR
Sbjct: 403 QSRSPSRSVSKEREHAKS-ESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSR 461
Query: 369 DREQDRKSKEKEKRGSDDKKSSVKSGSR 396
+ + + R +S +S SR
Sbjct: 462 SKSASKTRSRSKSRSRSASRSPSRSRSR 489
Score = 72.4 bits (176), Expect = 7e-13
Identities = 46/230 (20%), Positives = 103/230 (44%), Gaps = 6/230 (2%)
Query: 204 AQSRVDDHLMGKQHMGYAKIKA-TVEELKEKLRKRTEEPDRDERLKKEKQEREEREKERE 262
++ + ++ + ++G K ++ + + K K R R++E R+++EK+ R + +E
Sbjct: 269 SKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQE----RRVEEEKRGSVSRGRSQE 324
Query: 263 REREERERKRRREEEEREKERARDRERRKRS-RSRSRHSSRTSDRRCSRSRDHKRSRSRE 321
+ + + R + R + R+R + + KR R RSR SR+ R S+S ++ S+
Sbjct: 325 KSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKR 384
Query: 322 RRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEK 381
++ S +++ DRS+ + SRS + R ++ S + + +
Sbjct: 385 DSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRS 444
Query: 382 RGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEGDTQS 431
R + K ++ S SR + + T S+ + + +S ++S
Sbjct: 445 RSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
Score = 54.7 bits (130), Expect = 2e-07
Identities = 44/124 (35%), Positives = 58/124 (46%), Gaps = 25/124 (20%)
Query: 310 RSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRD 369
R R + RSRS R RSRSR R+SRS S + S+SR R RS SR R SKSR
Sbjct: 181 RRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSR------SKSRS 234
Query: 370 REQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESK-ESDTKNEVNGTSEDIKSEGD 428
R Q R +KEK S + +S+ S + + S+D ++E
Sbjct: 235 RSQSRSRSKKEKSRSP-----------------SKEKSRSRSHSAGKSRSKSKD-QAEEK 276
Query: 429 TQSN 432
Q+N
Sbjct: 277 IQNN 280
>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
Length = 330
Score = 97.1 bits (240), Expect = 3e-20
Identities = 66/193 (34%), Positives = 96/193 (49%), Gaps = 5/193 (2%)
Query: 215 KQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRR 274
K++ G A A++ + E EE D DE L K K + +E E + + + +
Sbjct: 132 KKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDAS--- 188
Query: 275 EEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSR 334
EEE+ K+++ R R K S SR SSR+S SRSR RSRS +SRSR R R
Sbjct: 189 EEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRER 248
Query: 335 SHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSG 394
S R K RS SR R S S ++SY S S +R + ++S+ + D KK +S
Sbjct: 249 SRSRGS-KSRSSSRSHRGSSSPRKRSYSSSSSSPERNR-KRSRSRSSSSGDRKKRRTRSR 306
Query: 395 SREKQSEDTNTES 407
S E++ ++ S
Sbjct: 307 SPERRHRSSSGSS 319
Score = 64.7 bits (156), Expect = 2e-10
Identities = 50/197 (25%), Positives = 89/197 (45%), Gaps = 12/197 (6%)
Query: 232 EKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRK 291
E + + + + DE +K+K+ R + +E +++ EEE+ ++ D + K
Sbjct: 113 EYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDE----DLSKYK 168
Query: 292 RSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRR 351
+ S S + ++ + RRSRS+ R SH RS + S S R
Sbjct: 169 LDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRS---SHSRSSSRSSSPSSSRS 225
Query: 352 RSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESD 411
RS+SR R S +S+SR ++R S+ + + +S S S K+S +++ S E +
Sbjct: 226 RSRSRSRSSSSSQSRSRSSSRER-SRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERN 284
Query: 412 TKNEVNGTSEDIKSEGD 428
K + +S S GD
Sbjct: 285 RKRSRSRSS----SSGD 297
>gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo
sapiens]
Length = 437
Score = 96.3 bits (238), Expect = 5e-20
Identities = 66/197 (33%), Positives = 99/197 (50%), Gaps = 29/197 (14%)
Query: 241 PDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHS 300
P RD + +ERE RE+ RER++E RER+R R + R + R+RD+E R+RSR RS+
Sbjct: 229 PHRD---RDRDRERERRERSRERDKE-RERRRSRSRDRRRRSRSRDKEERRRSRERSKDK 284
Query: 301 SRTSDRRCSRSRDHKRSRSRERR---RSRSRDRRRSR------------------SHDRS 339
R RR SRSR+ R R RER+ R D D
Sbjct: 285 DRDRKRRSSRSRERAR-RERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGP 343
Query: 340 ERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEK-EKRGSDDKKSSVKSGSREK 398
E K R R R+RRRS +R+ + R + RDR+++ K E+ +RG D+ + G ++
Sbjct: 344 EEKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDEARGG--GGGQDN 401
Query: 399 QSEDTNTESKESDTKNE 415
E +S++ ++E
Sbjct: 402 GLEGLGNDSRDMYMESE 418
Score = 75.5 bits (184), Expect = 9e-14
Identities = 57/196 (29%), Positives = 81/196 (41%), Gaps = 31/196 (15%)
Query: 230 LKEKLRKRTEEPDRDERLK---KEKQEREEREKEREREREERERKRRREEEEREKERARD 286
L + R R E +R ER + KE++ R R ++R R R+++ RR ER K++ RD
Sbjct: 228 LPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRD 287
Query: 287 RERR-KRSRSRSRHSSRTSDRRCSRSRDHKRSRSR--------------------ERRRS 325
R+RR RSR R+R + D +
Sbjct: 288 RKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKG 347
Query: 326 RSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSD 385
R RDR R RSH R R R RDR R + RDR +H+ R E+ R G D
Sbjct: 348 RDRDRERRRSH----RSERERRRDRDRDRDRDR---EHKRGERGSERGRDEARGGGGGQD 400
Query: 386 DKKSSVKSGSREKQSE 401
+ + + SR+ E
Sbjct: 401 NGLEGLGNDSRDMYME 416
Score = 68.9 bits (167), Expect = 8e-12
Identities = 48/138 (34%), Positives = 71/138 (51%), Gaps = 23/138 (16%)
Query: 257 REKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKR 316
R R+ ER R+++R R+RERR+RSR R + R+ +R
Sbjct: 209 RHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKE------------RERRR 256
Query: 317 SRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKS 376
SRSR+RRR RSR R +++ R RSR+R + K RDRK RS+ R R ++R+
Sbjct: 257 SRSRDRRR-RSRSR---------DKEERRRSRERSKDKDRDRKRRSSRSRERAR-RERER 305
Query: 377 KEKEKRGSDDKKSSVKSG 394
KE+ + G D ++G
Sbjct: 306 KEELRGGGGDMAEPSEAG 323
Score = 63.5 bits (153), Expect = 3e-10
Identities = 44/112 (39%), Positives = 57/112 (50%), Gaps = 17/112 (15%)
Query: 289 RRKRSRSRSRHSSRTSDRRCSRS--------RDHKRSRSRERR-RSRSRDRRRSRSHDRS 339
RR + RHS R R RD R R RERR RSR RD+ R R RS
Sbjct: 200 RRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRS 259
Query: 340 -ERKHRSRSRD-------RRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRG 383
+R+ RSRSRD R RSK +DR + S+SR+R + + +++E RG
Sbjct: 260 RDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERARRERERKEELRG 311
Score = 37.4 bits (85), Expect = 0.027
Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 9/94 (9%)
Query: 342 KHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDR------KSKEKEKRGSDDKKSSVKSGS 395
+H R R + HR + RDRE++R + KE+E+R S + +S S
Sbjct: 209 RHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRS 268
Query: 396 REKQSEDTNTE---SKESDTKNEVNGTSEDIKSE 426
R+K+ + E K+ D K + + E + E
Sbjct: 269 RDKEERRRSRERSKDKDRDRKRRSSRSRERARRE 302
>gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]
Length = 320
Score = 95.1 bits (235), Expect = 1e-19
Identities = 70/195 (35%), Positives = 99/195 (50%), Gaps = 11/195 (5%)
Query: 215 KQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRR 274
K++ G A A++ + E EE D DE L K K + +E E + + + +
Sbjct: 132 KKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDAS--- 188
Query: 275 EEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSR 334
EEE+ K+++ RR RS+SRS HS R+S R S S RSRSR R S S+ R RS
Sbjct: 189 EEEDSNKKKSN---RRSRSKSRSSHS-RSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSS 244
Query: 335 SHDRSE---RKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSV 391
S +RS K RS SR R S S ++SY S S +R + ++S+ + D KK
Sbjct: 245 SRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNR-KRSRSRSSSSGDRKKRRT 303
Query: 392 KSGSREKQSEDTNTE 406
+S S E Q NT+
Sbjct: 304 RSRSPESQVIGENTK 318
Score = 68.6 bits (166), Expect = 1e-11
Identities = 49/188 (26%), Positives = 81/188 (43%), Gaps = 5/188 (2%)
Query: 232 EKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRK 291
E + + + + DE +K+K+ R + +E +++ EEE+ ++ D + K
Sbjct: 113 EYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDE----DLSKYK 168
Query: 292 RSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRR-RSRSHDRSERKHRSRSRDR 350
+ S S + ++ + RRSRS+ R SRS RS SRSR R
Sbjct: 169 LDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSR 228
Query: 351 RRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKES 410
RS+S + RS SR+R + R SK + S SS + S S K S
Sbjct: 229 SRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRS 288
Query: 411 DTKNEVNG 418
+++ +G
Sbjct: 289 RSRSSSSG 296
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 94.0 bits (232), Expect = 2e-19
Identities = 66/223 (29%), Positives = 107/223 (47%), Gaps = 27/223 (12%)
Query: 231 KEKLRKRTEEPDRDERLKKEKQEREEREKERERE-REERERKRRR---EEEEREKERARD 286
K + R R+ P++ + + + R++ R R + R+ R R + +R + R+
Sbjct: 421 KARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPS 480
Query: 287 RER-------------RKRSRSRSRHSSRTSDRRCSRSRDHKRSRS----RERRRSRSRD 329
+ER +RSRS S+ R S+ RDH+RSRS R+RR+SRS +
Sbjct: 481 KERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPN 540
Query: 330 RRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEK---EKRGSDD 386
+ R RS RS + R + R SK RDR+ ++ SK R+R Q R S E+ + S +
Sbjct: 541 KERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPN 600
Query: 387 KKSSV---KSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSE 426
K+S ++ S+EK + T SKE + + E S+
Sbjct: 601 KQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQ 643
Score = 91.7 bits (226), Expect = 1e-18
Identities = 66/202 (32%), Positives = 100/202 (49%), Gaps = 25/202 (12%)
Query: 237 RTEEPDRDERLKKEKQEREERE------KEREREREERERKRRREEEEREKERARDRER- 289
R+ +RD R ++ R K+R+ R K R R +ARDR R
Sbjct: 369 RSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRS 428
Query: 290 ------RKRSRSRSRHSSRTSDRRCS--RSRDHKRSRSRERRRSRSRDRRRSRSHDRSER 341
R SRSRS + +R R S ++RDH RSRS + R RSR R S+ D S+
Sbjct: 429 RSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQL 488
Query: 342 KHRSRSRDRRRSK--SRDRKSYKHRSKSRDREQDRK---SKEKEKRGS-----DDKKSSV 391
S+ RD RRS+ S++R+ + RS S++R+ R SKE+++R S + +S
Sbjct: 489 GSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQS 548
Query: 392 KSGSREKQSEDTNTESKESDTK 413
+S S E++ + + SKE D +
Sbjct: 549 RSPSEEREHRQSRSPSKERDRR 570
Score = 87.8 bits (216), Expect = 2e-17
Identities = 58/207 (28%), Positives = 93/207 (44%), Gaps = 13/207 (6%)
Query: 231 KEKLRKRTEEPDRDERLKKEKQEREEREKERERERE-----------ERERKRRREEEER 279
+++ R R+ RD + + +R + R +E ER+ +R R +
Sbjct: 447 RDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKE 506
Query: 280 EKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRS 339
+ R ++R RSR S+ RR SRS + +R RS+ R S R+ R+SRS +
Sbjct: 507 RQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKE 566
Query: 340 ERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKK--SSVKSGSRE 397
+ R RS + R + + R S + R SR R +++S R S +K S ++ S+E
Sbjct: 567 RDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKE 626
Query: 398 KQSEDTNTESKESDTKNEVNGTSEDIK 424
+ T SKESD S D K
Sbjct: 627 GNHSQSRTSSKESDPSQSTVPRSPDWK 653
Score = 85.5 bits (210), Expect = 9e-17
Identities = 66/201 (32%), Positives = 96/201 (47%), Gaps = 21/201 (10%)
Query: 235 RKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSR 294
++R+ R +++ + KE R + K+R R +ARDR SR
Sbjct: 361 KERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDR-----SR 415
Query: 295 SRSRHSSRTSDRRCS--RSRDHKRSRS----RERRRSRSRDRRRSRSHDRSERKHRSRSR 348
SRS + +R R S ++RD RSRS R+R RSRS ++ R S RS K R RSR
Sbjct: 416 SRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSR 475
Query: 349 DRRRSKSRDRKSYKHRSKSRDREQDRK-SKEKEKRGS-------DDKKSSVKSGSREKQS 400
R SK RD SK RD + R SKE++ R S D ++S +S S+E+Q
Sbjct: 476 SRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRS--RSPSKERQR 533
Query: 401 EDTNTESKESDTKNEVNGTSE 421
+ + +KE D + + E
Sbjct: 534 RQSRSPNKERDRSQSRSPSEE 554
Score = 84.3 bits (207), Expect = 2e-16
Identities = 61/196 (31%), Positives = 88/196 (44%), Gaps = 19/196 (9%)
Query: 235 RKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRK--- 291
++R R +++ K R+R R K R R +ARDR R +
Sbjct: 397 KQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPN 456
Query: 292 --RSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRS--------HDRSER 341
R SRSR ++ DR SRS +R S+ S+ RD RRSRS RS
Sbjct: 457 KARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSS 516
Query: 342 KHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRK-SKEKEKRGS-----DDKKSSVKSGS 395
K R R R SK R R+ + +K RDR Q R S+E+E R S + + +S S
Sbjct: 517 KERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPS 576
Query: 396 REKQSEDTNTESKESD 411
+E++ + + S+E D
Sbjct: 577 KERERRQSRSSSEERD 592
Score = 82.8 bits (203), Expect = 6e-16
Identities = 63/213 (29%), Positives = 100/213 (46%), Gaps = 22/213 (10%)
Query: 231 KEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERR 290
KE+ +R+ P KE+Q R+ R +ER+ R + +E +R + R+ ++E
Sbjct: 493 KERDHRRSRSPS------KERQCRQSRSSSKERDH--RRSRSPSKERQRRQSRSPNKE-- 542
Query: 291 KRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDR 350
R RS+SR S + R SRS +R R R R S+ R+RR+SRS RSRS ++
Sbjct: 543 -RDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNK 601
Query: 351 RRSKSRDRKSYKHRSKSRDREQDRKSKEKEKR----GSDDKKSSV-------KSGSREKQ 399
+ SR R S K ++ SR R ++ + R SD +S+V +S +R
Sbjct: 602 QSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSS 661
Query: 400 SEDTNTESKESDTKNEVNGTSEDIKSEGDTQSN 432
T SK S + S+ D+Q++
Sbjct: 662 LSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQAD 694
Score = 80.1 bits (196), Expect = 4e-15
Identities = 60/195 (30%), Positives = 91/195 (46%), Gaps = 23/195 (11%)
Query: 249 KEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRC 308
K K + + R R R + + +++R+ R S R + S R+
Sbjct: 337 KGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPR-KESGRSQSGSP 395
Query: 309 SRSRDHKRSRS----RERRRSRS----RDRRRSR--------SHDRSERKHRSRSRDRRR 352
++ RDH RSRS R+R RSRS RDR RSR S RS K R RSR R
Sbjct: 396 NKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSP 455
Query: 353 SKSRDRKSYKHRSKSRDREQDR---KSKEKEKRGSDDKKSS---VKSGSREKQSEDTNTE 406
+K+RD + +K+RDR + R K ++ + GS K+ +S S+E+Q + +
Sbjct: 456 NKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSS 515
Query: 407 SKESDTKNEVNGTSE 421
SKE D + + + E
Sbjct: 516 SKERDHRRSRSPSKE 530
Score = 75.5 bits (184), Expect = 9e-14
Identities = 55/216 (25%), Positives = 99/216 (45%), Gaps = 10/216 (4%)
Query: 214 GKQHMGYAKIKA-TVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKR 272
G Q ++++++ + + + R RT + + + + + K + + R R +
Sbjct: 293 GSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRS 352
Query: 273 RREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRR 332
KER+ R S+ R S + + RS+ ++ R+ RSRS ++ R
Sbjct: 353 HNWSRNPSKERSHSHSRSS-SKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKAR 411
Query: 333 SRSHDRSERKHRSRSRDRRRSKSRD----RKSYKHRSKSRDREQDRKSKEKEKRGSDDK- 387
RS RS K R RSR R +K+RD R YK R +SR R + K+++ + S +K
Sbjct: 412 DRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPN-KARDHSRSRSPNKA 470
Query: 388 --KSSVKSGSREKQSEDTNTESKESDTKNEVNGTSE 421
+S +S S+E+ + SKE D + + + E
Sbjct: 471 RDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKE 506
Score = 75.1 bits (183), Expect = 1e-13
Identities = 58/227 (25%), Positives = 93/227 (40%), Gaps = 20/227 (8%)
Query: 206 SRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKERERER 265
S+ DH + + + + KE+ +R+ P KE+Q R+ R +ER+R
Sbjct: 492 SKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPS------KERQRRQSRSPNKERDR 545
Query: 266 EERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRS 325
+ E + + +++R+RR R RS S+ R R S RDH RSRS ++
Sbjct: 546 SQSRSPSEEREHRQSRSPSKERDRR-RWRSPSKERERRQSRSSSEERDHSRSRSPNKQSG 604
Query: 326 RSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSD 385
SR R S K ++ SR R SK + + SK D S+ R D
Sbjct: 605 YSRPRASS--------KEKAHSRSRTPSKEGNHSQSRTSSKESD-----PSQSTVPRSPD 651
Query: 386 DKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEGDTQSN 432
K+S ++ S + + T S T T S+ D ++
Sbjct: 652 WKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTS 698
Score = 63.5 bits (153), Expect = 3e-10
Identities = 52/157 (33%), Positives = 77/157 (49%), Gaps = 13/157 (8%)
Query: 261 REREREERERKRRREEEEREKERARDR---ERRKRSRSRSRHSSRTSDRRCSRS--RDHK 315
RE+ E R + + R+R + + R RSRS RT R S S R+H
Sbjct: 253 REKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHS 312
Query: 316 RSRSRERRRSRSRDRR--RSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQD 373
R+RSR R+ S+ R +SRSH + + +++SR+ R RS + R K RS S R
Sbjct: 313 RARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRS-- 370
Query: 374 RKSKEKEKRGSDDKKSS---VKSGSREKQSEDTNTES 407
SKE++ RGS + +SGS KQ + + + S
Sbjct: 371 -SSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRS 406
Score = 62.8 bits (151), Expect = 6e-10
Identities = 48/193 (24%), Positives = 77/193 (39%), Gaps = 15/193 (7%)
Query: 229 ELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRE 288
E+ +++ + R R + Q R R + R ++ + R +R RAR R
Sbjct: 261 EMSSRVKSYNQASTRS-RPQSHSQSRSPR-RSRSGSQKRTHSRVRSHSWKRNHSRARSRT 318
Query: 289 RR---------KRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDR- 338
R+ +SRS S+ S+ R R R H SR+ + RS S R S+ D
Sbjct: 319 RKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHR 378
Query: 339 ---SERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGS 395
S RK RS+ +K RD + +K+RDR + R + R + + S
Sbjct: 379 GSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCS 438
Query: 396 REKQSEDTNTESK 408
R + S+
Sbjct: 439 RSRSPYKARDRSR 451
Score = 60.8 bits (146), Expect = 2e-09
Identities = 48/207 (23%), Positives = 90/207 (43%), Gaps = 22/207 (10%)
Query: 204 AQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKERER 263
+ S+ DH + + + + KE+ R ++ P +E++ R+ R +ER
Sbjct: 514 SSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSP------SEEREHRQSRSPSKER 567
Query: 264 EREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERR 323
+R R R +E E R+ + + RSRS ++ S + R S+ + H RSR+ +
Sbjct: 568 DR-RRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKE 626
Query: 324 RSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRG 383
+ S+ R S+ D S+ RS D +RS +R ++R+ S+
Sbjct: 627 GNHSQSRTSSKESDPSQ-STVPRSPDWKRSPTRTSSLSQNRTPSKT-------------- 671
Query: 384 SDDKKSSVKSGSREKQSEDTNTESKES 410
S S+ SG + +D+ ++ S
Sbjct: 672 SSHSPSTFPSGGQTLSQDDSQADATTS 698
Score = 53.9 bits (128), Expect = 3e-07
Identities = 37/141 (26%), Positives = 65/141 (46%), Gaps = 2/141 (1%)
Query: 293 SRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRS--RDR 350
SR +S + S R S ++ RSR + +SRS R RS S R+ + RS S R+
Sbjct: 252 SREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNH 311
Query: 351 RRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKES 410
R++SR RK + + + + + + ++ + SR E +++ S+ S
Sbjct: 312 SRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSS 371
Query: 411 DTKNEVNGTSEDIKSEGDTQS 431
+ + G+S K G +QS
Sbjct: 372 SKERDHRGSSSPRKESGRSQS 392
Score = 47.0 bits (110), Expect = 3e-05
Identities = 48/177 (27%), Positives = 73/177 (41%), Gaps = 21/177 (11%)
Query: 271 KRRREEEEREKERARDRER---RKRSRSRSRHSSRTSDRRCSRSRD-HKRSRSRERRRSR 326
KR + R R + R R + +R+ +S+ SD RC + R H R R+ RR SR
Sbjct: 71 KRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSR 130
Query: 327 SRDRRRSRSHDRSE-RKHRSR--SRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRG 383
S R SR+ R H +R R R+ + +K + +S R R +R+ + + R
Sbjct: 131 SSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRN 190
Query: 384 SDDKKSSVKSGSREKQSED-------------TNTESKESDTKNEVNGTSEDIKSEG 427
K GS +S + T SKE + N +S +KS G
Sbjct: 191 LSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEK-SDNPSPSSSRKVKSYG 246
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 92.4 bits (228), Expect = 7e-19
Identities = 71/299 (23%), Positives = 142/299 (47%), Gaps = 32/299 (10%)
Query: 126 EEKIQVLTDKIDVLLQQIEELG----------SEGKVEEAQGMMKLVEQLKEERELLRST 175
EEK Q ++ D + Q+ EE E K++E + + +L+EE E LR
Sbjct: 224 EEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQ--RELQEEEEQLRKL 281
Query: 176 TSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLR 235
QE++ + + R + L KQ + + E +++ R
Sbjct: 282 ERQELRRERQEEEQQ------------QQRLRREQQLRRKQEE--ERREQQEERREQQER 327
Query: 236 KRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRE---RRKR 292
+ +E R+++L++E++ER E++ RE+E E RE++ RRE+EE +E+ RE RR++
Sbjct: 328 REQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQ 387
Query: 293 SRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRR- 351
R + R R + ++ RE++ R + RR + +R E+KH R++R
Sbjct: 388 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRL 447
Query: 352 RSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSS--VKSGSREKQSEDTNTESK 408
+ + +R+ + R + +R + + K++ KR ++++ +K E++ + E +
Sbjct: 448 KREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQ 506
Score = 86.7 bits (213), Expect = 4e-17
Identities = 89/386 (23%), Positives = 170/386 (44%), Gaps = 24/386 (6%)
Query: 59 EKIHDENLRKQYEKSSRFMKVGYERDFLRYLQSLLAEVE-RRIRRGHARLALSQNQQSSG 117
E+ ++ LR++ E+ R ++ E++ R Q L E + RR ++ L + QQ
Sbjct: 344 EERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRR 403
Query: 118 AAGPTGKNEEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLKEERELLRSTTS 177
+ + + + + L ++ EE E K E+ + +L + +E R+ L+
Sbjct: 404 EQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEE 463
Query: 178 TIESFAAQEKQM----EVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEK 233
T + KQ + E +L + + + R +Q ++ EE +E+
Sbjct: 464 TERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQ------LRREQEERREQ 517
Query: 234 LRKRTEEPDR-DERLKKEKQEREEREKERE----REREER-ERKRRREEEEREKERARDR 287
KR EE +R +RL+ E+Q R E+E+ RE RE E+R E++RR + +RE+E RD+
Sbjct: 518 RLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQ 577
Query: 288 ERRKRSRSRSRHSSRTSDRRC-SRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSR 346
++ R + R + R R + + R + R R +R +R ++ +S
Sbjct: 578 LLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSE 637
Query: 347 SRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTE 406
++ RR + R + REQ K +E+E+R K + RE++ + E
Sbjct: 638 EQEERRQQQ------LRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQE 691
Query: 407 SKESDTKNEVNGTSEDIKSEGDTQSN 432
K+ + ++SE D + +
Sbjct: 692 QARERIKSRIPKWQWQLESEADARQS 717
Score = 85.9 bits (211), Expect = 7e-17
Identities = 83/399 (20%), Positives = 170/399 (42%), Gaps = 51/399 (12%)
Query: 63 DENLRKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGAAGPT 122
+E +++E+ R ++ E++ R E ER + + L ++Q+
Sbjct: 431 EERHEQKHEQERREQRLKREQEERRDWLKREEETERH-EQERRKQQLKRDQEEERRERWL 489
Query: 123 GKNEEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLKEERELLRSTTSTIESF 182
EE+ + ++ + L++ +E E +++ + +L ++L+ E++L R E
Sbjct: 490 KLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQL 549
Query: 183 AAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTE--- 239
+E++ + + + + + R D L ++ ++K EE E+ KR E
Sbjct: 550 LKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVER 609
Query: 240 ---EPDRDERLKKEKQEREERE-----------KEREREREERER--------------- 270
E R++RLK+E+ E E R+ ++++ RE++ER
Sbjct: 610 LEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLE 669
Query: 271 ---KRRREEEEREKERARDRERRKRSRSRSR------HSSRTSDRRCSRSRDHKRSRSRE 321
KR EEE RE+E A + + + R R +SR +D R S+ R + +
Sbjct: 670 QRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQ 729
Query: 322 RRRSRSRDRRRSRSHD----RSERKHRSRSRDRRRSK-----SRDRKSYKHRSKSRDREQ 372
RRR ++RR R + ER HR + + +R + KS + R + R
Sbjct: 730 RRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPP 789
Query: 373 DRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESD 411
R+ +E++ R + ++ + E++ E + +E +
Sbjct: 790 LREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRERE 828
Score = 85.1 bits (209), Expect = 1e-16
Identities = 82/378 (21%), Positives = 175/378 (46%), Gaps = 65/378 (17%)
Query: 63 DENLRKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGAAGPT 122
++ LR++ EK R +ER + R L E E+ +R + L + ++
Sbjct: 1001 EQLLREEREKRRR---QEWERQY-RKKDELQQEEEQLLREEREKRRLQERERQY------ 1050
Query: 123 GKNEEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLKEERELLRSTTSTIESF 182
+ EE++Q Q+ E+L G+ E + +L Q ++E EL + +
Sbjct: 1051 -REEEELQ----------QEEEQL--LGEERETRRRQELERQYRKEEELQQEEEQLLREE 1097
Query: 183 AAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQH--MGYAKIKATVEELKEKLRKRTE- 239
+ ++ E + Q R ++ L ++ + + K +EL+ + R+ E
Sbjct: 1098 PEKRRRQE-----------RERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEV 1146
Query: 240 ----------EPDRDERLKKEKQEREEREK----------EREREREERERKRRREEE-- 277
EP++ R + E+Q REE E E+E+ R+ERER+ R EEE
Sbjct: 1147 QQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQ 1206
Query: 278 -EREKERARDRERR---KRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRS 333
++ K+R RD ++R K + ++ ++ + R++++ R E + R R ++
Sbjct: 1207 RQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQD 1266
Query: 334 RSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKS 393
H E++ R R ++RRR + RDR + + +RE+ +++K ++++ ++K+ +
Sbjct: 1267 LQHLLGEQQERDREQERRRWQQRDR--HFPEEEQLEREEQKEAKRRDRKSQEEKQLLREE 1324
Query: 394 GSREKQSEDTNTESKESD 411
+++ ++T+ + +E +
Sbjct: 1325 REEKRRRQETDRKFREEE 1342
Score = 84.3 bits (207), Expect = 2e-16
Identities = 45/193 (23%), Positives = 101/193 (52%), Gaps = 6/193 (3%)
Query: 229 ELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREER---ERKRRREEEEREKERAR 285
E +E R+R EE + +RL++E+Q R ++E+ER ++EER + +R ++EE RE++ R
Sbjct: 282 ERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRR 341
Query: 286 DRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRS---RERRRSRSRDRRRSRSHDRSERK 342
++E R+ + R +++ R ++ +R RE++ R + RR + R ++
Sbjct: 342 EQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQL 401
Query: 343 HRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSED 402
R + R + R+++ + + R++E++R ++ E+ + + + R+ +
Sbjct: 402 RREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKRE 461
Query: 403 TNTESKESDTKNE 415
TE E + + +
Sbjct: 462 EETERHEQERRKQ 474
Score = 83.2 bits (204), Expect = 4e-16
Identities = 59/279 (21%), Positives = 127/279 (45%), Gaps = 26/279 (9%)
Query: 163 EQLKEERELLRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAK 222
E+ +E +L R + +EKQ + + R D ++ + K
Sbjct: 202 EEFPDEEQLRRRELLELRRKGREEKQQQ-------------RRERQDRVFQEEEEKEWRK 248
Query: 223 IKATVEELKEKLRKRTEEPDRDERLKKEKQ-----EREEREKEREREREERERKRRREEE 277
+ + + +EKL++ EEP R L++E++ ER+E +ER+ E ++++R RR ++
Sbjct: 249 RETVLRKEEEKLQE--EEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQL 306
Query: 278 EREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDR-----RR 332
R++E R ++ +R + R + R R+ + R ++ RR + +R RR
Sbjct: 307 RRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRR 366
Query: 333 SRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVK 392
+ +R E++ R + RR + R + + + R +Q R+ ++ + ++ ++
Sbjct: 367 EQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 426
Query: 393 SGSREKQSEDTN-TESKESDTKNEVNGTSEDIKSEGDTQ 430
E++ E + E +E K E + +K E +T+
Sbjct: 427 REQEEERHEQKHEQERREQRLKREQEERRDWLKREEETE 465
Score = 82.8 bits (203), Expect = 6e-16
Identities = 66/299 (22%), Positives = 138/299 (46%), Gaps = 12/299 (4%)
Query: 124 KNEEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLKEERELLRSTTSTIESFA 183
K+E Q L+ + + Q+ +L +E + + Q + E+ ++ R R ++ F
Sbjct: 776 KSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQ-FL 834
Query: 184 AQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRT--EEP 241
+E+Q++ E D + ++ K + +EE + K R+ T +P
Sbjct: 835 EEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEE-ERKRRRHTLYAKP 893
Query: 242 DRDERLKKEKQEREEREKERERE------REERERKRRREEEEREKERARDRERRKRSRS 295
E+L+KE+Q +E E+E +RE R+E+ER+ R EE+ +++E RE R++ R
Sbjct: 894 ALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRR 953
Query: 296 RSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRR-RSRSHDRSERKHRSRSRDRRRSK 354
+ R D++ + + E+RR + R+++ R + E + R +R +
Sbjct: 954 QERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRR 1013
Query: 355 SRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTK 413
+ Y+ + + + E+ +E+EKR +++ + E Q E+ +E +T+
Sbjct: 1014 QEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYRE-EEELQQEEEQLLGEERETR 1071
Score = 80.5 bits (197), Expect = 3e-15
Identities = 81/382 (21%), Positives = 172/382 (45%), Gaps = 39/382 (10%)
Query: 59 EKIHDENLRKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGA 118
EK + +QY K + E + L + ++ R R+ L Q ++
Sbjct: 1009 EKRRRQEWERQYRKKDELQQ---EEEQLLREEREKRRLQERERQYREEEELQQEEEQLLG 1065
Query: 119 AGPTGKNEEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLKEERELLRSTTST 178
+ ++++ K + L Q+ E+L E E + + Q +EE EL +
Sbjct: 1066 EERETRRRQELERQYRKEEELQQEEEQLLREEP--EKRRRQERERQCREEEELQQEEEQL 1123
Query: 179 IESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQH--MGYAKIKATVEELKEKLRK 236
+ + ++ E+ + Q R ++ + ++ + K +EL+ + R+
Sbjct: 1124 LREEREKRRRQEL-----------ERQYREEEEVQQEEEQLLREEPEKRRRQELERQYRE 1172
Query: 237 RTEEPDRDERLKKEKQEREEREKERE-REREERERKRR----REEEER---------EKE 282
E +E+L +E+QE+ +E+ER+ RE EE +R++R R+E++R EKE
Sbjct: 1173 EEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKE 1232
Query: 283 RA-RDRE----RRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHD 337
A RD + R+ + R S+ DR+ + H +ER R + R R + R
Sbjct: 1233 NAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRH 1292
Query: 338 RSERKHRSRSRDRRRSKSRDRKSYKHRSKSRD-REQDRKSKEKEKRGSDDKKSSVKSGSR 396
E + R +++ +K RDRKS + + R+ RE+ R+ +E +++ ++++ + +
Sbjct: 1293 FPEEEQLERE-EQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQ 1351
Query: 397 EKQSEDTNTESKESDTKNEVNG 418
+ ++ + + +E + +++ G
Sbjct: 1352 PLRRQERDRKFREEELRHQEQG 1373
Score = 79.3 bits (194), Expect = 6e-15
Identities = 63/284 (22%), Positives = 127/284 (44%), Gaps = 26/284 (9%)
Query: 144 EELGSEGKVEEAQGMMKLVEQLKEERELLRSTTSTIESFAAQEKQMEVCEVCGAFLIVGD 203
++L + + E + +KL E+ + E++ R E +E++++ E
Sbjct: 474 QQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQE---------- 523
Query: 204 AQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKE-RE 262
+ R+ L +Q + + + + LK + KR E+ R++RLK+E +EER + +
Sbjct: 524 EEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKRE---QEERRDQLLK 580
Query: 263 REREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRER 322
RE E R+++ +RE+EER ++R + RE +R R R R + +S E+
Sbjct: 581 REEERRQQRLKREQEERLEQRLK-REEVERLEQEERREQRLKREEPEEERRQQLLKSEEQ 639
Query: 323 RRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEK- 381
R + RR + R +R R +R + + + R + E+ +++E+ K
Sbjct: 640 EERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKS 699
Query: 382 ----------RGSDDKKSSVKSGSREKQSEDTNTESKESDTKNE 415
+D ++S V S R+++ + E +E + E
Sbjct: 700 RIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRE 743
Score = 76.3 bits (186), Expect = 5e-14
Identities = 73/335 (21%), Positives = 151/335 (45%), Gaps = 19/335 (5%)
Query: 60 KIHDENLRKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGAA 119
++ ++ +R+Q E+ +FM+ + Q L E +R+ R L + QQ
Sbjct: 1582 RLEEQKVRRQ-EQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQE 1640
Query: 120 G--------PTGKNEEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLKEEREL 171
P + +E+ Q L D ++ E+L EG+ ++ + + + +EE++L
Sbjct: 1641 RDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQL 1700
Query: 172 LRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELK 231
R F +E+Q+ E+ F + + + +Q Y KI +
Sbjct: 1701 RRQERE--RKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQER-YRKILEEEQLRP 1757
Query: 232 EKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREE---EEREKERARDRE 288
E+ ++ +RD + ++E+Q R+ERE+++ R +E +RK R EE +ERE+++ R ++
Sbjct: 1758 EREEQQLRRQERDRKFREEEQLRQEREEQQLRS-QESDRKFREEEQLRQEREEQQLRPQQ 1816
Query: 289 RRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSR 348
R + R + R ++ R+ E+ ++ + RR + + E + R + R
Sbjct: 1817 RDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQER 1876
Query: 349 DRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRG 383
+R+ + R+ K + R Q + K +E +G
Sbjct: 1877 ERKLREEHIRRQQKEEQRHR---QVGEIKSQEGKG 1908
Score = 73.6 bits (179), Expect = 3e-13
Identities = 67/308 (21%), Positives = 139/308 (45%), Gaps = 26/308 (8%)
Query: 124 KNEEKIQVLTDKIDVLLQQIEE----LGSEGKVEEAQGMMKLVEQLKEERELLRSTTSTI 179
K EEK+Q + LQ+ EE L + E Q + ++L+ E++L R
Sbjct: 255 KEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEE-- 312
Query: 180 ESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTE 239
E QE++ E E + R + L +Q E +++LR+ E
Sbjct: 313 ERREQQEERREQQERRE------QQEERREQQLRREQE----------ERREQQLRREQE 356
Query: 240 EPDRDERLKKEKQEREEREKERERERE-ERERKRRREEEEREKERARDRERRKRSRSRSR 298
E R+++L++E QE E RE++ RE++ RE++ RRE++ R +++ R ++ +R + R
Sbjct: 357 EERREQQLRRE-QEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 415
Query: 299 HSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDR 358
+++ R ++ +R + + R + +R + R K + R + R +
Sbjct: 416 EQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEET--ERHEQERRK 473
Query: 359 KSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNG 418
+ K + RE+ K +E+E+R +++ +E++ E +E + +
Sbjct: 474 QQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLR 533
Query: 419 TSEDIKSE 426
+ + ++ E
Sbjct: 534 SEQQLRRE 541
Score = 73.2 bits (178), Expect = 4e-13
Identities = 73/321 (22%), Positives = 143/321 (44%), Gaps = 42/321 (13%)
Query: 122 TGKNEEKIQVLTDKIDVLLQQIEELGS------EGKVEEAQGMMKLVEQLKEERELLRST 175
TG +EEK K +L + +E + ++EE G + ++ ++EREL
Sbjct: 93 TGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQEREL---- 148
Query: 176 TSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQH-MGYAKIKATVEELKEKL 234
A E+Q E E L D Q R ++ +Q + +A E+L+
Sbjct: 149 -------AEGEEQSEKQER----LEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCK 197
Query: 235 RKRTEE-PDRDERLKKE--------KQEREEREKERE----REREERERKRR----REEE 277
TEE PD ++ ++E ++E++++ +ER+ +E EE+E ++R R+EE
Sbjct: 198 GHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEE 257
Query: 278 EREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRD---HKRSRSRERRRSRSRDRRRSR 334
E+ +E R+R + + R R + +R R ++ R + + RR +
Sbjct: 258 EKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQ 317
Query: 335 SHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSG 394
+R E++ R ++ RR + R+ + R + REQ+ + +E++ R +++ +
Sbjct: 318 QEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQL 377
Query: 395 SREKQSEDTNTESKESDTKNE 415
RE+Q +E + E
Sbjct: 378 RREQQLRREQQLRREQQLRRE 398
Score = 73.2 bits (178), Expect = 4e-13
Identities = 89/373 (23%), Positives = 160/373 (42%), Gaps = 26/373 (6%)
Query: 64 ENLRKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGAAGPTG 123
E RK E+ + + ER FL Q L E R+ R L + QQ
Sbjct: 1427 ERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRK 1486
Query: 124 KNEEKIQVLTDKIDVLLQQIEELGSEGK---VEEAQGMMKLVEQ---LKEERELLRSTTS 177
EE+ Q+ + D ++ E E + +EE Q + + Q L+EE++L R
Sbjct: 1487 FLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERG 1546
Query: 178 TIE------SFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELK 231
F +E+ + E D + R+++ + +Q K ++L+
Sbjct: 1547 QQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQE-RKFMEDEQQLR 1605
Query: 232 --EKLRKRTEEPDR----DERLKKEKQEREEREKEREREREERERKRRREEEEREKERAR 285
E ++ +E DR DE+L +E++E++ +ER+R+ E E + RR+E E++ R
Sbjct: 1606 RQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDR 1665
Query: 286 DRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSR---DRRRSRSHDRSERK 342
DR+ R+ + + RR R R + + RR+ R R + ERK
Sbjct: 1666 DRKFREEEQ-LLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERK 1724
Query: 343 HRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKE--KRGSDDKKSSVKSGSREKQS 400
R + R+ ++ + + K + EQ R +E++ +R D+K + R+++
Sbjct: 1725 FREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQER- 1783
Query: 401 EDTNTESKESDTK 413
E+ S+ESD K
Sbjct: 1784 EEQQLRSQESDRK 1796
Score = 72.4 bits (176), Expect = 7e-13
Identities = 64/239 (26%), Positives = 118/239 (49%), Gaps = 40/239 (16%)
Query: 203 DAQSRVD-DHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDR----DERLKKEKQEREER 257
D QS+ D HL+G+Q E +E+ R+R ++ DR +E+L++E+Q+ +R
Sbjct: 1260 DRQSQQDLQHLLGEQQ----------ERDREQERRRWQQRDRHFPEEEQLEREEQKEAKR 1309
Query: 258 --------------EKEREREREERERKRRREE---EEREKERARDRERRKRSRSRS-RH 299
E+E +R R+E +RK R EE +ERE++ R +ER ++ R RH
Sbjct: 1310 RDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRH 1369
Query: 300 SSR----TSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKS 355
+ + + R ++ +R +E ++ R ++R + DR +RK R + R +
Sbjct: 1370 QEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDR-DRKFREEEQQLSR-QE 1427
Query: 356 RDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQS-EDTNTESKESDTK 413
RDRK + + R +E++RK E+E++ ++ + + Q E+ +E D K
Sbjct: 1428 RDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRK 1486
Score = 72.4 bits (176), Expect = 7e-13
Identities = 74/355 (20%), Positives = 155/355 (43%), Gaps = 34/355 (9%)
Query: 59 EKIHDENLRKQYEKSSRFMKVGYERDFLRYLQS--LLAEVERRIRRGHARLALSQNQQSS 116
E++ E +Q + R K E +R + E E+++RR + L Q +
Sbjct: 1561 EQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDR- 1619
Query: 117 GAAGPTGKNEEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVE---QLKEERELLR 173
K E Q+L ++ + QQ+ + K E + ++ E QL+ +R+
Sbjct: 1620 -------KFREDEQLLQEREE---QQLHRQERDRKFLEEEPQLRRQEREQQLRHDRD--- 1666
Query: 174 STTSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEK 233
F +E+ ++ E D + R ++ + +Q ++ + +++
Sbjct: 1667 ------RKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQE 1720
Query: 234 LRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDR-----E 288
L ++ E +E+L++E ++ + R +ER R+ E E+ R EE++ + + RDR E
Sbjct: 1721 LERKFRE---EEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEE 1777
Query: 289 RRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRD-RRRSRSHDRSERKHRSRS 347
+ ++ R + S+ SDR+ ++ R ++ R + RD + R + R
Sbjct: 1778 QLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRL 1837
Query: 348 RDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSED 402
R R + R + + + KSR EQ+ +E++KR + ++ + R +Q E+
Sbjct: 1838 RQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEE 1892
Score = 72.0 bits (175), Expect = 1e-12
Identities = 60/282 (21%), Positives = 128/282 (45%), Gaps = 36/282 (12%)
Query: 161 LVEQLKEERELLRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQH--M 218
L EQL++E++LL+ ++ ++++ + E Q R ++ L ++ +
Sbjct: 895 LQEQLRKEQQLLQEEEEELQREEREKRRRQEQE----------RQYREEEQLQQEEEQLL 944
Query: 219 GYAKIKATVEELKEKLRKRT-----------EEPDRDERLKKEKQEREEREKERERE--- 264
+ K +E + + RK EEP++ R ++EK+ REE E ++E E
Sbjct: 945 REEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLL 1004
Query: 265 REERERKRRRE--------EEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKR 316
REERE++RR+E +E +++E RE R++ R + R + + +
Sbjct: 1005 REEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLL 1064
Query: 317 SRSRERRRSRSRDR--RRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDR 374
RE RR + +R R+ + E + ++RR + R+R+ + ++ EQ
Sbjct: 1065 GEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLL 1124
Query: 375 KSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEV 416
+ + +++R + ++ + +++ E E E + E+
Sbjct: 1125 REEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQEL 1166
Score = 72.0 bits (175), Expect = 1e-12
Identities = 83/377 (22%), Positives = 159/377 (42%), Gaps = 32/377 (8%)
Query: 59 EKIH-DENLRKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSG 117
+++H E RK E+ + + +R F R + E ER+ +L Q Q+
Sbjct: 1476 QQLHRQERDRKFLEEEQQLRRQERDRKF-REQELRSQEPERKFLEEEQQLHRQQRQRKFL 1534
Query: 118 AAGPTGKNEEKIQVLTDKIDVLLQQIEELGSEGKVE-----EAQGMMKLVEQLKEERELL 172
+ +E+ Q D ++ E+L E + + E +L EQ +E
Sbjct: 1535 QEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQE 1594
Query: 173 RSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQ-----HMGYAKIKATV 227
R + QE Q ++ + D + R D+ L+ ++ H K
Sbjct: 1595 RKFMEDEQQLRRQEGQQQLRQE-------RDRKFREDEQLLQEREEQQLHRQERDRKFLE 1647
Query: 228 EE--LKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEE---REKE 282
EE L+ + R++ DRD + ++E+Q +E E+++ R R+ER+RK R EE++ +E+E
Sbjct: 1648 EEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLR-RQERDRKFREEEQQLRRQERE 1706
Query: 283 RARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERK 342
R +E ++ R R ++ + + R R+ ++ R +R E++
Sbjct: 1707 RKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRP---EREEQQ 1763
Query: 343 HRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKE----KRGSDDKKSSVKSGSREK 398
R + RDR+ + + + + R +E DRK +E+E +R + + G
Sbjct: 1764 LRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRW 1823
Query: 399 QSEDTNTESKESDTKNE 415
+ E E +E + E
Sbjct: 1824 EEEQLQLEEQEQRLRQE 1840
Score = 72.0 bits (175), Expect = 1e-12
Identities = 87/382 (22%), Positives = 166/382 (43%), Gaps = 30/382 (7%)
Query: 67 RKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGAAGPTGKNE 126
RK E+ + + +R FL+ Q L RR RG R + + E
Sbjct: 1515 RKFLEEEQQLHRQQRQRKFLQEEQQL-----RRQERGQQRRQDRDRKFREEEQLRQEREE 1569
Query: 127 EKI--QVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVE---QLKEEREL-LRSTTSTIE 180
+++ Q K + Q++ E K E + ++ E QL++ER+ R ++
Sbjct: 1570 QQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQ 1629
Query: 181 SFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEE 240
+E+Q+ E FL + Q R + +H K + + L+E ++
Sbjct: 1630 E--REEQQLHRQERDRKFL-EEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRR 1686
Query: 241 PDRDERLKKEKQE--REEREK-----EREREREERERKRRREE---EEREKERARDRER- 289
+RD + ++E+Q+ R+ERE+ E++ R+E ERK R EE +E E+E+ R +ER
Sbjct: 1687 QERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERY 1746
Query: 290 RKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDR----SERKHRS 345
RK R + + RD K + R+ R + RS+ DR E+ +
Sbjct: 1747 RKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQE 1806
Query: 346 RSRDRRRSKSRDRK-SYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTN 404
R + R + RD K ++ + ++ R +E++++ +++ + + SR ++ E
Sbjct: 1807 REEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQ 1866
Query: 405 TESKESDTKNEVNGTSEDIKSE 426
E ++ + E E I+ +
Sbjct: 1867 EEEQKRRQERERKLREEHIRRQ 1888
Score = 70.9 bits (172), Expect = 2e-12
Identities = 82/385 (21%), Positives = 169/385 (43%), Gaps = 30/385 (7%)
Query: 59 EKIHDENLRKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGA 118
++ DE+ R + K RD Y + E R++ R SQ
Sbjct: 1212 QRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLL 1271
Query: 119 AGPTGKNEEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQ---LKEERELLRST 175
++ E+ + + D + E+L E + E + K E+ L+EERE R
Sbjct: 1272 GEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRR 1331
Query: 176 TSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEE------ 229
T F +E+ ++ E D + R ++ +Q + + + +
Sbjct: 1332 QETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERK 1391
Query: 230 -LKEKLRKRTEE------PDRDERLKKEKQEREEREKERE-REREERERKRRREEEEREK 281
LKE+ + R +E DRD + ++E+Q+ +E++R+ RE E++ R++ RE + E+
Sbjct: 1392 FLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEE 1451
Query: 282 ERARDRERRKRSRSRSRHSSRTSDRRCSR-SRDHKRSRSRERRRSRSRDRR------RSR 334
E+ +ER ++ R + +++ R RD K ++ R + RDR+ RS+
Sbjct: 1452 EQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQ 1511
Query: 335 SHDR----SERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKE--KRGSDDKK 388
+R E++ + R R+ + + + R + R +++DRK +E+E ++ ++++
Sbjct: 1512 EPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQ 1571
Query: 389 SSVKSGSREKQSEDTNTESKESDTK 413
S + R+ + E+ +E + K
Sbjct: 1572 LSRQERDRKFRLEEQKVRRQEQERK 1596
Score = 70.1 bits (170), Expect = 4e-12
Identities = 90/403 (22%), Positives = 168/403 (41%), Gaps = 62/403 (15%)
Query: 67 RKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGAAGPTGKNE 126
R+Q E+ + +K ER R + +E+R++R L Q ++ E
Sbjct: 569 REQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVE-RLEQEERREQRLKREEPEE 627
Query: 127 EKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLKEERELLRS-TTSTIESFAAQ 185
E+ Q L + ++ ++L E + Q + + E+ + E+ L R E A+
Sbjct: 628 ERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAE 687
Query: 186 EKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATV-----EELKEKLRKRTEE 240
E+Q + E + + Q +++ +Q Y++ + +E +EK R+R E
Sbjct: 688 EEQEQARERIKSR--IPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESE 745
Query: 241 PD--RDERLKKEKQEREER-----------EKERERER--------EERERKRRREE--- 276
+ER +++QE E+R + ER R+R E+RER+ R EE
Sbjct: 746 LQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQ 805
Query: 277 -------EEREKERARDRERRKRSR-----------SRSRHSSRTSDRRCSRSRDHKRSR 318
EE EKE+ R R+RR+R + R + + + D +R R
Sbjct: 806 REQRFLPEEEEKEQRR-RQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRR 864
Query: 319 SRERRRSR--------SRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDR 370
S+E+RR + R RRR + + + + R + + + + R K R +
Sbjct: 865 SQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQ 924
Query: 371 EQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTK 413
EQ+R+ +E+E+ ++++ + REK+ D K
Sbjct: 925 EQERQYREEEQLQQEEEQ--LLREEREKRRRQERERQYRKDKK 965
Score = 69.7 bits (169), Expect = 5e-12
Identities = 61/277 (22%), Positives = 123/277 (44%), Gaps = 20/277 (7%)
Query: 153 EEAQGMMKLVEQLKEERELLRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHL 212
EE Q + + L+EERE R E ++K+++ E ++G+ +
Sbjct: 932 EEEQLQQEEEQLLREEREKRRRQER--ERQYRKDKKLQQKEE----QLLGEEPEKRRRQE 985
Query: 213 MGKQHMGYAKIKATVEEL--KEKLRKRTEEPDRDERLKKEKQE------REEREKER--E 262
K++ +++ E+L +E+ ++R +E +R R K E Q+ REEREK R E
Sbjct: 986 REKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQE 1045
Query: 263 REREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRER 322
RER+ RE + ++EEE+ R+ RR+ + R R+ R R+
Sbjct: 1046 RERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQE 1105
Query: 323 RRSRSRDRRRSRSHD----RSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKE 378
R + R+ + + R ER+ R R R+ + + + R+ + R+ +E
Sbjct: 1106 RERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQE 1165
Query: 379 KEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNE 415
E++ ++++ + ++ ++ + +E + E
Sbjct: 1166 LERQYREEEELQQEEEQLLREEQEKRRQERERQYREE 1202
Score = 69.3 bits (168), Expect = 6e-12
Identities = 65/305 (21%), Positives = 137/305 (44%), Gaps = 21/305 (6%)
Query: 124 KNEEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLKEERELLRSTTSTIESFA 183
+ E+ Q L ++ D L + E S+ + + + +L E+ K R L + + E
Sbjct: 841 QRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLR 900
Query: 184 AQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEEL--KEKLRKRTEEP 241
+++ ++ E + + + + +Q+ +++ E+L +E+ ++R +E
Sbjct: 901 KEQQLLQEEEE----ELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQER 956
Query: 242 DRDERLKKEKQEREER------EKER--EREREERERKRRREEEEREKERARDRERRKRS 293
+R R K+ Q++EE+ EK R ERE++ RE EE ++E+E+ ER KR
Sbjct: 957 ERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYRE----EEELQQEEEQLLREEREKRR 1012
Query: 294 RSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDR--RRSRSHDRSERKHRSRSRDRR 351
R R D + + RE+RR + R+R R + E + R+ R
Sbjct: 1013 RQEWERQYRKKD-ELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETR 1071
Query: 352 RSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESD 411
R + +R+ K ++ EQ + + +++R + ++ + +++ E E +E
Sbjct: 1072 RRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKR 1131
Query: 412 TKNEV 416
+ E+
Sbjct: 1132 RRQEL 1136
Score = 68.6 bits (166), Expect = 1e-11
Identities = 80/350 (22%), Positives = 138/350 (39%), Gaps = 46/350 (13%)
Query: 86 LRYLQSLLAEVERRIRRGHARLALSQNQQSSGAAGPTGKNEEKIQVLTD----------- 134
LR Q LL E E ++R Q Q+ + EE+ Q+L +
Sbjct: 899 LRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEE-QLLREEREKRRRQERE 957
Query: 135 ---KIDVLLQQIEE--LGSEGKVEEAQGMMKLVEQLKEERELLRSTTSTIESFAAQEKQM 189
+ D LQQ EE LG E + Q K + +EE EL + + + ++
Sbjct: 958 RQYRKDKKLQQKEEQLLGEEPEKRRRQEREK---KYREEEELQQEEEQLLREEREKRRRQ 1014
Query: 190 EVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKK 249
E + Q R D L ++ + E +EK +R +E +R R ++
Sbjct: 1015 E-----------WERQYRKKDELQQEEEQ-------LLREEREK--RRLQERERQYREEE 1054
Query: 250 EKQEREER--EKEREREREERERKRRREEEE--REKERARDRERRKRSRSRSRHSSRTSD 305
E Q+ EE+ +ERE R + ++ R+EEE +E+E+ E KR R R +
Sbjct: 1055 ELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEE 1114
Query: 306 RRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRS 365
R +RRR + R + E + R +R + + Y+
Sbjct: 1115 ELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEE 1174
Query: 366 KSRDREQDRKSKEKEKRGSDDKKS--SVKSGSREKQSEDTNTESKESDTK 413
+ + E+ +E+EKR + ++ + R+K+ + E + SD K
Sbjct: 1175 ELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLK 1224
Score = 67.8 bits (164), Expect = 2e-11
Identities = 85/393 (21%), Positives = 175/393 (44%), Gaps = 47/393 (11%)
Query: 60 KIHDENLRKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIR---RGHARLALSQNQQSS 116
K+ +E R+Q E+ R ++ E++ R + E E R++ R +L Q ++
Sbjct: 490 KLEEEERREQQER--REQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERRE 547
Query: 117 GAAGPTGKNEEKIQVLTDKIDVLLQQIEELGSEG--KVEEAQGMMKLVEQLKE--ERELL 172
K EE+ ++ ++ + L++ +E + K EE + +L + +E E+ L
Sbjct: 548 QLL----KREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLK 603
Query: 173 RSTTSTIESFAAQEKQM---EVCEVCGAFLIVGDAQS--RVDDHLMGKQHMGYAKIKATV 227
R +E +E+++ E E L+ + Q R +Q ++K
Sbjct: 604 REEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREE 663
Query: 228 EE--LKEKLRKRTEEPDRDERLKKEKQER-EEREKER--------EREREERERK----- 271
EE L+++L++ EE R++ L +E+QE+ ER K R E E + R+ K
Sbjct: 664 EEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRP 723
Query: 272 -----RRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSR 326
+RR +E+ EK R R+ E + + R+ + ++R RD E + R
Sbjct: 724 RKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQR----RDFTWQWQAEEKSER 779
Query: 327 SRDRRRSRSHDRSERKHRSRSRDRRRSKSR----DRKSYKHRSKSRDREQDRKSKEKEKR 382
R R +R R +R+ + R+ +R++ + R + + + R + R+RE++ + E+E++
Sbjct: 780 GRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQ 839
Query: 383 GSDDKKSSVKSGSREKQSEDTNTESKESDTKNE 415
+++ + ED + +++
Sbjct: 840 LQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQ 872
Score = 67.0 bits (162), Expect = 3e-11
Identities = 74/364 (20%), Positives = 158/364 (43%), Gaps = 32/364 (8%)
Query: 59 EKIHDENLRKQYEKSSRFMKVGYERDFLRYL-----QSLLAEVERRIRRGHARLALSQNQ 113
E+ ++ L++Q E+ ++ E+ R Q L E E+R+ + L + Q
Sbjct: 512 EERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQ 571
Query: 114 QSSGAAGPTGKNEEKIQVLTDKIDVLLQQI---EELGSEGKVEEAQGMMKLVEQLKEERE 170
+ + E + Q L + + L+Q EE+ + E + +K E +E R+
Sbjct: 572 EERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQ 631
Query: 171 LLRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEEL 230
L + E Q+ + E E L + + R++ L ++H + + EE
Sbjct: 632 QLLKSEEQ-EERRQQQLRREQQERREQRLKREEEEERLEQRLK-REHEEERREQELAEEE 689
Query: 231 KEKLRKRTEE--PDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRE 288
+E+ R+R + P +L+ E R+ + R R++E + R++ +EE+ R +E +
Sbjct: 690 QEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQ 749
Query: 289 RRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRS----RSRDRRRSRSHDRSERKHR 344
+R+ + + + D + K R R+R + R + R+ R+ +R +R+ R
Sbjct: 750 EEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQR 809
Query: 345 ----SRSRDRRRSKSRDRK------------SYKHRSKSRDREQDRKSKEKEKRGSDDKK 388
+++RR + R+R+ + R++ E+D +++E+R S +++
Sbjct: 810 FLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQR 869
Query: 389 SSVK 392
K
Sbjct: 870 RDQK 873
Score = 66.6 bits (161), Expect = 4e-11
Identities = 77/304 (25%), Positives = 140/304 (46%), Gaps = 22/304 (7%)
Query: 95 EVERRIRRGHA--RLALSQNQQSSGAAGPTGKNEEKIQVLTDKIDVLLQQIEELGSEGKV 152
E +RR R+ +L + ++ K E+ Q+L ++ + L++ +E + +
Sbjct: 1306 EAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRR-QERDRKFRE 1364
Query: 153 EEAQGMMKLVEQLKEERELLRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHL 212
EE + + + L+EE+ L R F +E+Q+ E D + R ++
Sbjct: 1365 EELRHQEQGRKFLEEEQRLRRQERE--RKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQ 1422
Query: 213 MGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKE---RERE----- 264
+ +Q K EE + + ++R + +E+ ++++ R+ RE+E +ERE
Sbjct: 1423 LSRQERDR---KFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLH 1479
Query: 265 REERERKRRREEEE-REKERARD-RERRKRSRSRSRHSSRTSDR--RCSRSRDHKRSRSR 320
R+ER+RK EE++ R +ER R RE+ RS+ R + R R R + +
Sbjct: 1480 RQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQ 1539
Query: 321 ERRRSRSRDRR--RSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKE 378
RR+ R + RR R R E+ + R + + RDRK K R +EQ+RK E
Sbjct: 1540 LRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFME 1599
Query: 379 KEKR 382
E++
Sbjct: 1600 DEQQ 1603
Score = 66.2 bits (160), Expect = 5e-11
Identities = 65/307 (21%), Positives = 127/307 (41%), Gaps = 46/307 (14%)
Query: 138 VLLQQIEELGSEGKVEEAQGMMKLVEQLKEERELLRSTTSTIESFAAQEKQMEVCEVCGA 197
+L ++ EEL E + E + + Q +EE +L + + + ++ E
Sbjct: 905 LLQEEEEELQREER--EKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQE------- 955
Query: 198 FLIVGDAQSRVDDHLMGKQH--MGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQERE 255
+ Q R D L K+ +G K +E ++K R+ E +E+L +E++E+
Sbjct: 956 ----RERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKR 1011
Query: 256 EREKEREREREERERKRRREE------EEREKERARDRERRKRSRSRSRH-------SSR 302
R+ E ER+ R++ ++E EEREK R ++RER+ R + R
Sbjct: 1012 RRQ---EWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEER 1068
Query: 303 TSDRRCSRSRDHKRSR--------------SRERRRSRSRDRRRSRSHDRSERKHRSRSR 348
+ RR R +++ + RR+ R R R + E + R
Sbjct: 1069 ETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREER 1128
Query: 349 DRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESK 408
++RR + +R+ Y+ + + E+ +E EKR + + + +Q E+ +
Sbjct: 1129 EKRRRQELERQ-YREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREE 1187
Query: 409 ESDTKNE 415
+ + E
Sbjct: 1188 QEKRRQE 1194
Score = 65.9 bits (159), Expect = 7e-11
Identities = 84/387 (21%), Positives = 161/387 (41%), Gaps = 51/387 (13%)
Query: 57 PCEKIHDENLRKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSS 116
P E+ + L+ + ++ R ++ E+ R + E E R+ + R + ++
Sbjct: 625 PEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQE 684
Query: 117 GAAGPTGKNEEKIQVLTDKIDVLLQQIEELGSEGKV----EEAQGMMKLVEQLKEERELL 172
A + E+I+ K L+ E + KV + +G + EQ +E+R
Sbjct: 685 LAEEEQEQARERIKSRIPKWQWQLES-EADARQSKVYSRPRKQEGQRRRQEQ-EEKRRRR 742
Query: 173 RSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKE 232
S E A +Q E E F A+ + + G+Q + + + E +E
Sbjct: 743 ESELQWQEEERAHRQQQEE-EQRRDFTWQWQAEEKSE---RGRQRLS---ARPPLREQRE 795
Query: 233 KLRKRTEEPDRDERLKKEKQERE-------EREK-----EREREREERERKRRREEEE-- 278
+ + E R++R E++E+E EREK E E + + RER ++ +EEE
Sbjct: 796 RQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDG 855
Query: 279 --REKERARDRERRK---------RSRSRSRHS----------SRTSDRRCSRSRDHKRS 317
++ER R +E+R+ R R RH+ R + + +
Sbjct: 856 LQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQR 915
Query: 318 RSRERRRSRSRDR--RRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRK 375
RE+RR + ++R R + E + R++RR + R+R+ Y+ K + +E+
Sbjct: 916 EEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQ-YRKDKKLQQKEEQLL 974
Query: 376 SKEKEKRGSDDKKSSVKSGSREKQSED 402
+E EKR +++ + +Q E+
Sbjct: 975 GEEPEKRRRQEREKKYREEEELQQEEE 1001
Score = 63.2 bits (152), Expect = 5e-10
Identities = 76/377 (20%), Positives = 160/377 (42%), Gaps = 27/377 (7%)
Query: 66 LRKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGAAGPTGKN 125
LR++ E+ R + +R F Q L E+ +RR + + G
Sbjct: 1321 LREEREEKRRRQET--DRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLE 1378
Query: 126 EEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLKEERELLRSTTSTIESFAAQ 185
EE+ ++ L++ ++L + + E Q + +EE + L S F +
Sbjct: 1379 EEQRLRRQERERKFLKEEQQLRCQER--EQQLRQDRDRKFREEEQQL-SRQERDRKFREE 1435
Query: 186 EKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDE 245
E+Q+ E FL + L ++H + + + ++E +E+ R E RD
Sbjct: 1436 EQQVRRQERERKFL-------EEEQQLRQERHRKFREEEQLLQEREEQQLHRQE---RDR 1485
Query: 246 RLKKEKQE--REERE-KEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSR 302
+ +E+Q+ R+ER+ K RE+E +E +R+ EEE++ R + + + + + R R
Sbjct: 1486 KFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQER 1545
Query: 303 TSDRRCSRSRDHKRSRS--RERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKS 360
RR R R + +ER + + R R E+K R + ++R+ + +
Sbjct: 1546 GQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLR 1605
Query: 361 YKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVN--- 417
+ + +E+DRK +E E+ + ++ + R+++ + + + + + ++
Sbjct: 1606 RQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDR 1665
Query: 418 ----GTSEDIKSEGDTQ 430
E + EG+ Q
Sbjct: 1666 DRKFREEEQLLQEGEEQ 1682
Score = 62.0 bits (149), Expect = 1e-09
Identities = 51/204 (25%), Positives = 91/204 (44%), Gaps = 23/204 (11%)
Query: 233 KLRKRTEEPDRDERLKKEKQEREEREKERER--------------EREE-RERKRRREEE 277
+LR R + D + L E+QER+ RE+ER R EREE +E KRR +
Sbjct: 1257 QLRDRQSQQDL-QHLLGEQQERD-REQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKS 1314
Query: 278 EREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRD---HKRSRSRERRRSRSRDRRRSR 334
+ EK+ R+ KR R + R ++ + ++ R R+ R R + + R
Sbjct: 1315 QEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGR 1374
Query: 335 SHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEK---RGSDDKKSSV 391
E++ R + R+R+ K + + R + +++DRK +E+E+ R D+K
Sbjct: 1375 KFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFRE 1434
Query: 392 KSGSREKQSEDTNTESKESDTKNE 415
+ +Q + +E + E
Sbjct: 1435 EEQQVRRQERERKFLEEEQQLRQE 1458
Score = 61.6 bits (148), Expect = 1e-09
Identities = 46/213 (21%), Positives = 97/213 (45%), Gaps = 21/213 (9%)
Query: 235 RKRTEEPDRDERLKKEKQERE------EREKEREREREERERKRRREEEEREKERARDRE 288
R R E + +R ++++QE+E E + E++ E+R+R+RR EE R+++ ++RE
Sbjct: 125 RDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQERE 184
Query: 289 RRKRSRS-----RSRHSSRTSDRRCSRSRD--HKRSRSRERRRSRSRDRRRSRSHDRSER 341
R+ + + D R R+ R + RE ++ + R+R+ + E+
Sbjct: 185 ERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEK 244
Query: 342 KHRSRSRDRRR--SKSRDRKSYKHRSKSRDREQDRK------SKEKEKRGSDDKKSSVKS 393
+ R R R+ K ++ + + R + EQ RK +E+++ ++ +
Sbjct: 245 EWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQ 304
Query: 394 GSREKQSEDTNTESKESDTKNEVNGTSEDIKSE 426
R KQ E+ + +E + E E+ + +
Sbjct: 305 QLRRKQEEERREQQEERREQQERREQQEERREQ 337
Score = 61.2 bits (147), Expect = 2e-09
Identities = 51/197 (25%), Positives = 92/197 (46%), Gaps = 8/197 (4%)
Query: 220 YAKIKATVEELKEKLRKRTEEPDRDERLKKEKQER-EEREKEREREREERERKRRREEEE 278
YA +AT + +++ R +E +R ++E Q R E R+++ E E +R R++R+E+E
Sbjct: 87 YALGQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQER 146
Query: 279 REKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDR 338
E E+++R R R + D R R + + RE RR+ + + H+
Sbjct: 147 ELAEGEEQSEKQERLEQRDR---QRRDEELWRQR--QEWQEREERRAEEEQLQSCKGHET 201
Query: 339 SERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREK 398
E + R R + R RK + + + R QDR +E+E++ K+ +V EK
Sbjct: 202 EEFPDEEQLRRRELLELR-RKGREEKQQQRRERQDRVFQEEEEK-EWRKRETVLRKEEEK 259
Query: 399 QSEDTNTESKESDTKNE 415
E+ +E + E
Sbjct: 260 LQEEEPQRQRELQEEEE 276
Score = 56.6 bits (135), Expect = 4e-08
Identities = 81/384 (21%), Positives = 159/384 (41%), Gaps = 60/384 (15%)
Query: 64 ENLRKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLA-----LSQNQQSSGA 118
+ L +QY K + E LR E E+R R+ R L Q ++
Sbjct: 1074 QELERQYRKEEELQQE--EEQLLR------EEPEKRRRQERERQCREEEELQQEEEQLLR 1125
Query: 119 AGPTGKNEEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLKEERELLRSTTST 178
+ ++++ + + + Q+ E+L E E + +L Q +EE EL +
Sbjct: 1126 EEREKRRRQELERQYREEEEVQQEEEQLLREEP--EKRRRQELERQYREEEELQQEEEQL 1183
Query: 179 IESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRT 238
+ QEK+ + E Q R ++ L ++ + + +LK +
Sbjct: 1184 LRE--EQEKRRQERE----------RQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEK 1231
Query: 239 EEPDRDERLKKEKQEREE---------REKERERER-----EERERKRRREEEEREKERA 284
E RD ++ + +E E+ R+++ +++ E++ER R E+ER + +
Sbjct: 1232 ENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDR---EQERRRWQQ 1288
Query: 285 RDR---ERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRR----RSRSHD 337
RDR E + R + + R DR+ + R E+RR + DR+ +
Sbjct: 1289 RDRHFPEEEQLEREEQKEAKR-RDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQE 1347
Query: 338 RSERKHRSRSRDRR------RSKSRDRKSYKHRSKSRDREQDRK--SKEKEKRGSDDKKS 389
R E+ R + RDR+ R + + RK + + R +E++RK +E++ R + ++
Sbjct: 1348 REEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQ 1407
Query: 390 SVKSGSREKQSEDTNTESKESDTK 413
+ R+ + E+ +E D K
Sbjct: 1408 LRQDRDRKFREEEQQLSRQERDRK 1431
Score = 49.7 bits (117), Expect = 5e-06
Identities = 53/249 (21%), Positives = 112/249 (44%), Gaps = 39/249 (15%)
Query: 64 ENLRKQYEKSSRFMKVGYERDFLRYLQSLLA-EVERRIRRGHARLALSQNQQSSGAAGPT 122
E RK E+ + + ER FL+ Q L E+ER+ R ++ +Q
Sbjct: 1688 ERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQL------- 1740
Query: 123 GKNEEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLKEERELLRSTTSTIESF 182
+ +E+ + + ++ + ++ E+ + + +E + EQL++ERE + + +
Sbjct: 1741 -RRQERYRKILEEEQLRPEREEQ---QLRRQERDRKFREEEQLRQEREEQQLRSQESDRK 1796
Query: 183 AAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPD 242
+E+Q+ Q R + L +Q G + + +L+E+ ++ +E D
Sbjct: 1797 FREEEQLR--------------QEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERD 1842
Query: 243 RD----------ERLKKEKQE---REEREKEREREREERERKRRREEEEREKERARDRER 289
R E+ ++E+QE EE+++ +ERER+ RE RR+++E ++ R +
Sbjct: 1843 RQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIK 1902
Query: 290 RKRSRSRSR 298
+ + R
Sbjct: 1903 SQEGKGHGR 1911
Score = 48.5 bits (114), Expect = 1e-05
Identities = 40/173 (23%), Positives = 77/173 (44%), Gaps = 13/173 (7%)
Query: 256 EREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHK 315
+ EK + +E + RR+EE++ + RDR+ + R R + +R + +
Sbjct: 96 DEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEE-- 153
Query: 316 RSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSR--DREQD 373
+S ++ R RDR+R R + ++ + R+ RR++ +S K D EQ
Sbjct: 154 --QSEKQERLEQRDRQR-RDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQL 210
Query: 374 RKSK--EKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIK 424
R+ + E ++G ++K+ RE+Q E ++ K E E+ K
Sbjct: 211 RRRELLELRRKGREEKQQQ----RRERQDRVFQEEEEKEWRKRETVLRKEEEK 259
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 90.9 bits (224), Expect = 2e-18
Identities = 72/221 (32%), Positives = 106/221 (47%), Gaps = 18/221 (8%)
Query: 220 YAKIKATVEELKEKLR--KRTEEPDRDERLK-KEKQEREEREKEREREREERERKRRREE 276
+ K+K T E+ K+ K +E RD L+ + K+ + K R+R E R R R+R
Sbjct: 1793 FVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSS 1852
Query: 277 EE---REKERARDRERRKRSRSRSRHSSR----TSDRRCSRSRDHK-RSRSRERRRSRSR 328
+ R + R+R R RR+R SRSR SR S + RS H+ +SR R+R+RS SR
Sbjct: 1853 KSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSR 1912
Query: 329 DRR-----RSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRG 383
D R RSR+ R R H R R RS R R+S+ R R R+S+ +R
Sbjct: 1913 DNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGR-RRSFSISPSRRSRTPSRRSRTPSRRS 1971
Query: 384 -SDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDI 423
+ ++S S S + T S+ +++ V S I
Sbjct: 1972 RTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSI 2012
Score = 84.7 bits (208), Expect = 1e-16
Identities = 61/160 (38%), Positives = 89/160 (55%), Gaps = 16/160 (10%)
Query: 241 PDR-DERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRH 299
P+R E +EK + E K ++ + ++ K R ++ EKE+ RD R RS+ RS+
Sbjct: 1776 PERASESSSEEKDDYEIFVKVKDTHEKSKKNKNR---DKGEKEKKRDSSLRSRSK-RSKS 1831
Query: 300 SSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRR---SKSR 356
S S +R S SR R RS + + RS+ R RSRS R R RSRS+ R R SK +
Sbjct: 1832 SEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSR-RRRRSSRSRSKSRGRRSVSKEK 1890
Query: 357 DRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSR 396
++S KHRSKSR+R++ R S S D + +V++ SR
Sbjct: 1891 RKRSPKHRSKSRERKRKRSS-------SRDNRKTVRARSR 1923
Score = 84.7 bits (208), Expect = 1e-16
Identities = 71/200 (35%), Positives = 106/200 (53%), Gaps = 21/200 (10%)
Query: 238 TEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRS 297
+EE D E K K E+ +K + R++ E+E+KR R K R + +SR R+
Sbjct: 1784 SEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSK---RSKSSEHKSRKRT 1840
Query: 298 RHSSRTSDRRCSRSRDHK---RSRSRERRR---SRSRDR---RRSRSHDRSER--KHRSR 346
S + +R S+S+ H+ RSRSR RRR SRSR + RRS S ++ +R KHRS+
Sbjct: 1841 SESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSK 1900
Query: 347 SRD--RRRSKSRD-RKSYKHRSK--SRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQ-- 399
SR+ R+RS SRD RK+ + RS+ SR S+ + R ++S S SR +
Sbjct: 1901 SRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTP 1960
Query: 400 SEDTNTESKESDTKNEVNGT 419
S + T S+ S T + + T
Sbjct: 1961 SRRSRTPSRRSRTPSRRSRT 1980
Score = 73.9 bits (180), Expect = 3e-13
Identities = 59/173 (34%), Positives = 86/173 (49%), Gaps = 17/173 (9%)
Query: 235 RKRTEEPDRDERLKKEKQEREEREKEREREREERER--KRRREEEEREKERARDRERRKR 292
R +T R R ++ + R + R +E+R+R K R + ER+++R+ R+ RK
Sbjct: 1858 RSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKT 1917
Query: 293 SRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSER----KHRSRSR 348
R+RSR SR RSR H SR RRRSRS RRRS S S R RSR+
Sbjct: 1918 VRARSRTPSR-------RSRSHTPSR---RRRSRSVGRRRSFSISPSRRSRTPSRRSRTP 1967
Query: 349 DRR-RSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQS 400
RR R+ SR ++ RS++ R S+ + R ++S S R ++S
Sbjct: 1968 SRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRS 2020
Score = 63.2 bits (152), Expect = 5e-10
Identities = 65/202 (32%), Positives = 90/202 (44%), Gaps = 35/202 (17%)
Query: 215 KQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRR 274
K H + ++ + R R++ R + KEK++R + + + RER+ RKR
Sbjct: 1855 KSHRSQTRSRSRSRRRRRSSRSRSKSRGR-RSVSKEKRKRSPKHRSKSRERK---RKRSS 1910
Query: 275 EEEEREKERARDRERRKRSRSRS---RHSSRTSDRRCS-------RSRDHKRSRSRERRR 324
+ R+ RAR R +RSRS + R SR+ RR S RSR R RR
Sbjct: 1911 SRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRR 1970
Query: 325 SRSRDRR------RSRSHDRSER----KHRSRSRDRRRSKS-------RDRKSYKHR-SK 366
SR+ RR RSR+ R R + RSRS RRRS S R R + R S+
Sbjct: 1971 SRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSR 2030
Query: 367 SRDREQDRKSKEKEKRGSDDKK 388
S R RK +RG K+
Sbjct: 2031 SPIR---RKRSRSSERGRSPKR 2049
Score = 35.8 bits (81), Expect = 0.078
Identities = 23/126 (18%), Positives = 56/126 (44%), Gaps = 1/126 (0%)
Query: 292 RSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRR 351
R RS + + R S S ++ + + + ++ +R + + +
Sbjct: 1763 RDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSL 1822
Query: 352 RSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESD 411
RS+S+ KS +H+S+ R E +++++ + S +S +S SR ++ ++ +S
Sbjct: 1823 RSRSKRSKSSEHKSRKRTSESRSRARKRSSK-SKSHRSQTRSRSRSRRRRRSSRSRSKSR 1881
Query: 412 TKNEVN 417
+ V+
Sbjct: 1882 GRRSVS 1887
Score = 34.3 bits (77), Expect = 0.23
Identities = 13/59 (22%), Positives = 35/59 (59%)
Query: 287 RERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRS 345
+E ++SR S + T + +S+ HK+ +++++++ + ++++ R + SE K +S
Sbjct: 84 KEGSRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESESKTKS 142
Score = 30.4 bits (67), Expect = 3.3
Identities = 22/92 (23%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 340 ERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQ 399
ER S S ++ + + H +++ +D+ KEK KR S + S +S S E +
Sbjct: 1777 ERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEK-KRDSSLRSRSKRSKSSEHK 1835
Query: 400 SEDTNTESKESDTKNEVNGTSEDIKSEGDTQS 431
S +ES+ K S ++ ++S
Sbjct: 1836 SRKRTSESRSRARKRSSKSKSHRSQTRSRSRS 1867
Score = 28.9 bits (63), Expect = 9.5
Identities = 32/152 (21%), Positives = 58/152 (38%), Gaps = 18/152 (11%)
Query: 285 RDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRS------RSHDR 338
+D ER R+ SD RS S R S S + + D
Sbjct: 1740 KDMERLTSLRAGIEGPLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDT 1799
Query: 339 SERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSK---EKEKRGSDDKKSSVKSGS 395
E+ ++++RD+ + + S + RSK +SK K ++ + + +S + S
Sbjct: 1800 HEKSKKNKNRDKGEKEKKRDSSLRSRSK--------RSKSSEHKSRKRTSESRSRARKRS 1851
Query: 396 REKQSEDTNTESKESDTKNEVNGTSEDIKSEG 427
+ +S + T S+ + + S KS G
Sbjct: 1852 SKSKSHRSQTRSRSRSRRRRRSSRSRS-KSRG 1882
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 90.9 bits (224), Expect = 2e-18
Identities = 72/221 (32%), Positives = 106/221 (47%), Gaps = 18/221 (8%)
Query: 220 YAKIKATVEELKEKLR--KRTEEPDRDERLK-KEKQEREEREKEREREREERERKRRREE 276
+ K+K T E+ K+ K +E RD L+ + K+ + K R+R E R R R+R
Sbjct: 1793 FVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSS 1852
Query: 277 EE---REKERARDRERRKRSRSRSRHSSR----TSDRRCSRSRDHK-RSRSRERRRSRSR 328
+ R + R+R R RR+R SRSR SR S + RS H+ +SR R+R+RS SR
Sbjct: 1853 KSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSR 1912
Query: 329 DRR-----RSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRG 383
D R RSR+ R R H R R RS R R+S+ R R R+S+ +R
Sbjct: 1913 DNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGR-RRSFSISPSRRSRTPSRRSRTPSRRS 1971
Query: 384 -SDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDI 423
+ ++S S S + T S+ +++ V S I
Sbjct: 1972 RTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSI 2012
Score = 84.7 bits (208), Expect = 1e-16
Identities = 61/160 (38%), Positives = 89/160 (55%), Gaps = 16/160 (10%)
Query: 241 PDR-DERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRH 299
P+R E +EK + E K ++ + ++ K R ++ EKE+ RD R RS+ RS+
Sbjct: 1776 PERASESSSEEKDDYEIFVKVKDTHEKSKKNKNR---DKGEKEKKRDSSLRSRSK-RSKS 1831
Query: 300 SSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRR---SKSR 356
S S +R S SR R RS + + RS+ R RSRS R R RSRS+ R R SK +
Sbjct: 1832 SEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSR-RRRRSSRSRSKSRGRRSVSKEK 1890
Query: 357 DRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSR 396
++S KHRSKSR+R++ R S S D + +V++ SR
Sbjct: 1891 RKRSPKHRSKSRERKRKRSS-------SRDNRKTVRARSR 1923
Score = 84.7 bits (208), Expect = 1e-16
Identities = 71/200 (35%), Positives = 106/200 (53%), Gaps = 21/200 (10%)
Query: 238 TEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRS 297
+EE D E K K E+ +K + R++ E+E+KR R K R + +SR R+
Sbjct: 1784 SEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSK---RSKSSEHKSRKRT 1840
Query: 298 RHSSRTSDRRCSRSRDHK---RSRSRERRR---SRSRDR---RRSRSHDRSER--KHRSR 346
S + +R S+S+ H+ RSRSR RRR SRSR + RRS S ++ +R KHRS+
Sbjct: 1841 SESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSK 1900
Query: 347 SRD--RRRSKSRD-RKSYKHRSK--SRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQ-- 399
SR+ R+RS SRD RK+ + RS+ SR S+ + R ++S S SR +
Sbjct: 1901 SRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTP 1960
Query: 400 SEDTNTESKESDTKNEVNGT 419
S + T S+ S T + + T
Sbjct: 1961 SRRSRTPSRRSRTPSRRSRT 1980
Score = 73.9 bits (180), Expect = 3e-13
Identities = 59/173 (34%), Positives = 86/173 (49%), Gaps = 17/173 (9%)
Query: 235 RKRTEEPDRDERLKKEKQEREEREKEREREREERER--KRRREEEEREKERARDRERRKR 292
R +T R R ++ + R + R +E+R+R K R + ER+++R+ R+ RK
Sbjct: 1858 RSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKT 1917
Query: 293 SRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSER----KHRSRSR 348
R+RSR SR RSR H SR RRRSRS RRRS S S R RSR+
Sbjct: 1918 VRARSRTPSR-------RSRSHTPSR---RRRSRSVGRRRSFSISPSRRSRTPSRRSRTP 1967
Query: 349 DRR-RSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQS 400
RR R+ SR ++ RS++ R S+ + R ++S S R ++S
Sbjct: 1968 SRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRS 2020
Score = 63.2 bits (152), Expect = 5e-10
Identities = 65/202 (32%), Positives = 90/202 (44%), Gaps = 35/202 (17%)
Query: 215 KQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRR 274
K H + ++ + R R++ R + KEK++R + + + RER+ RKR
Sbjct: 1855 KSHRSQTRSRSRSRRRRRSSRSRSKSRGR-RSVSKEKRKRSPKHRSKSRERK---RKRSS 1910
Query: 275 EEEEREKERARDRERRKRSRSRS---RHSSRTSDRRCS-------RSRDHKRSRSRERRR 324
+ R+ RAR R +RSRS + R SR+ RR S RSR R RR
Sbjct: 1911 SRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRR 1970
Query: 325 SRSRDRR------RSRSHDRSER----KHRSRSRDRRRSKS-------RDRKSYKHR-SK 366
SR+ RR RSR+ R R + RSRS RRRS S R R + R S+
Sbjct: 1971 SRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSR 2030
Query: 367 SRDREQDRKSKEKEKRGSDDKK 388
S R RK +RG K+
Sbjct: 2031 SPIR---RKRSRSSERGRSPKR 2049
Score = 35.8 bits (81), Expect = 0.078
Identities = 23/126 (18%), Positives = 56/126 (44%), Gaps = 1/126 (0%)
Query: 292 RSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRR 351
R RS + + R S S ++ + + + ++ +R + + +
Sbjct: 1763 RDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSL 1822
Query: 352 RSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESD 411
RS+S+ KS +H+S+ R E +++++ + S +S +S SR ++ ++ +S
Sbjct: 1823 RSRSKRSKSSEHKSRKRTSESRSRARKRSSK-SKSHRSQTRSRSRSRRRRRSSRSRSKSR 1881
Query: 412 TKNEVN 417
+ V+
Sbjct: 1882 GRRSVS 1887
Score = 34.3 bits (77), Expect = 0.23
Identities = 13/59 (22%), Positives = 35/59 (59%)
Query: 287 RERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRS 345
+E ++SR S + T + +S+ HK+ +++++++ + ++++ R + SE K +S
Sbjct: 84 KEGSRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESESKTKS 142
Score = 30.4 bits (67), Expect = 3.3
Identities = 22/92 (23%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 340 ERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQ 399
ER S S ++ + + H +++ +D+ KEK KR S + S +S S E +
Sbjct: 1777 ERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEK-KRDSSLRSRSKRSKSSEHK 1835
Query: 400 SEDTNTESKESDTKNEVNGTSEDIKSEGDTQS 431
S +ES+ K S ++ ++S
Sbjct: 1836 SRKRTSESRSRARKRSSKSKSHRSQTRSRSRS 1867
Score = 28.9 bits (63), Expect = 9.5
Identities = 32/152 (21%), Positives = 58/152 (38%), Gaps = 18/152 (11%)
Query: 285 RDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRS------RSHDR 338
+D ER R+ SD RS S R S S + + D
Sbjct: 1740 KDMERLTSLRAGIEGPLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDT 1799
Query: 339 SERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSK---EKEKRGSDDKKSSVKSGS 395
E+ ++++RD+ + + S + RSK +SK K ++ + + +S + S
Sbjct: 1800 HEKSKKNKNRDKGEKEKKRDSSLRSRSK--------RSKSSEHKSRKRTSESRSRARKRS 1851
Query: 396 REKQSEDTNTESKESDTKNEVNGTSEDIKSEG 427
+ +S + T S+ + + S KS G
Sbjct: 1852 SKSKSHRSQTRSRSRSRRRRRSSRSRS-KSRG 1882
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.125 0.334
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,724,560
Number of Sequences: 37866
Number of extensions: 793576
Number of successful extensions: 69089
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1446
Number of HSP's successfully gapped in prelim test: 934
Number of HSP's that attempted gapping in prelim test: 9835
Number of HSP's gapped (non-prelim): 19208
length of query: 432
length of database: 18,247,518
effective HSP length: 105
effective length of query: 327
effective length of database: 14,271,588
effective search space: 4666809276
effective search space used: 4666809276
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.