Guide to the Human Genome
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Search of human proteins with 19913410

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19913410 major vault protein [Homo sapiens]
         (893 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19913410 major vault protein [Homo sapiens]                       1753   0.0  
gi|19913412 major vault protein [Homo sapiens]                       1753   0.0  
gi|41322923 plectin 1 isoform 11 [Homo sapiens]                        47   1e-04
gi|41322914 plectin 1 isoform 10 [Homo sapiens]                        47   1e-04
gi|41322919 plectin 1 isoform 8 [Homo sapiens]                         47   1e-04
gi|41322910 plectin 1 isoform 7 [Homo sapiens]                         47   1e-04
gi|41322916 plectin 1 isoform 6 [Homo sapiens]                         47   1e-04
gi|41322908 plectin 1 isoform 3 [Homo sapiens]                         47   1e-04
gi|41322912 plectin 1 isoform 2 [Homo sapiens]                         47   1e-04
gi|47607492 plectin 1 isoform 1 [Homo sapiens]                         47   1e-04
gi|94538362 flotillin 2 [Homo sapiens]                                 46   2e-04
gi|191252785 centrobin, centrosomal BRCA2 interacting protein is...    46   2e-04
gi|80861396 centrobin, centrosomal BRCA2 interacting protein iso...    46   2e-04
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              45   3e-04
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]         44   7e-04
gi|157042792 coiled-coil domain containing 64B [Homo sapiens]          44   7e-04
gi|93102364 SWAP-70 protein [Homo sapiens]                             44   9e-04
gi|154354979 myosin X [Homo sapiens]                                   44   9e-04
gi|115648142 centrosomal protein 164kDa [Homo sapiens]                 43   0.001
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]                43   0.001
gi|4504063 golgin 97 [Homo sapiens]                                    43   0.001
gi|31982906 cingulin-like 1 [Homo sapiens]                             43   0.001
gi|4505101 microtubule-associated protein 7 [Homo sapiens]             43   0.001
gi|87298937 centrosomal protein 110kDa [Homo sapiens]                  43   0.001
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]     42   0.002
gi|35038601 spindle assembly abnormal protein 6 [Homo sapiens]         42   0.003
gi|88196790 coiled-coil domain containing 88 [Homo sapiens]            42   0.003
gi|5031699 flotillin 1 [Homo sapiens]                                  42   0.003
gi|4505257 moesin [Homo sapiens]                                       42   0.003
gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo s...    42   0.003

>gi|19913410 major vault protein [Homo sapiens]
          Length = 893

 Score = 1753 bits (4541), Expect = 0.0
 Identities = 893/893 (100%), Positives = 893/893 (100%)

Query: 1   MATEEFIIRIPPYHYIHVLDQNSNVSRVEVGPKTYIRQDNERVLFAPMRMVTVPPRHYCT 60
           MATEEFIIRIPPYHYIHVLDQNSNVSRVEVGPKTYIRQDNERVLFAPMRMVTVPPRHYCT
Sbjct: 1   MATEEFIIRIPPYHYIHVLDQNSNVSRVEVGPKTYIRQDNERVLFAPMRMVTVPPRHYCT 60

Query: 61  VANPVSRDAQGLVLFDVTGQVRLRHADLEIRLAQDPFPLYPGEVLEKDITPLQVVLPNTA 120
           VANPVSRDAQGLVLFDVTGQVRLRHADLEIRLAQDPFPLYPGEVLEKDITPLQVVLPNTA
Sbjct: 61  VANPVSRDAQGLVLFDVTGQVRLRHADLEIRLAQDPFPLYPGEVLEKDITPLQVVLPNTA 120

Query: 121 LHLKALLDFEDKDGDKVVAGDEWLFEGPGTYIPRKEVEVVEIIQATIIRQNQALRLRARK 180
           LHLKALLDFEDKDGDKVVAGDEWLFEGPGTYIPRKEVEVVEIIQATIIRQNQALRLRARK
Sbjct: 121 LHLKALLDFEDKDGDKVVAGDEWLFEGPGTYIPRKEVEVVEIIQATIIRQNQALRLRARK 180

Query: 181 ECWDRDGKERVTGEEWLVTTVGAYLPAVFEEVLDLVDAVILTEKTALHLRARRNFRDFRG 240
           ECWDRDGKERVTGEEWLVTTVGAYLPAVFEEVLDLVDAVILTEKTALHLRARRNFRDFRG
Sbjct: 181 ECWDRDGKERVTGEEWLVTTVGAYLPAVFEEVLDLVDAVILTEKTALHLRARRNFRDFRG 240

Query: 241 VSRRTGEEWLVTVQDTEAHVPDVHEEVLGVVPITTLGPHNYCVILDPVGPDGKNQLGQKR 300
           VSRRTGEEWLVTVQDTEAHVPDVHEEVLGVVPITTLGPHNYCVILDPVGPDGKNQLGQKR
Sbjct: 241 VSRRTGEEWLVTVQDTEAHVPDVHEEVLGVVPITTLGPHNYCVILDPVGPDGKNQLGQKR 300

Query: 301 VVKGEKSFFLQPGEQLEQGIQDVYVLSEQQGLLLRALQPLEEGEDEEKVSHQAGDHWLIR 360
           VVKGEKSFFLQPGEQLEQGIQDVYVLSEQQGLLLRALQPLEEGEDEEKVSHQAGDHWLIR
Sbjct: 301 VVKGEKSFFLQPGEQLEQGIQDVYVLSEQQGLLLRALQPLEEGEDEEKVSHQAGDHWLIR 360

Query: 361 GPLEYVPSAKVEVVEERQAIPLDENEGIYVQDVKTGKVRAVIGSTYMLTQDEVLWEKELP 420
           GPLEYVPSAKVEVVEERQAIPLDENEGIYVQDVKTGKVRAVIGSTYMLTQDEVLWEKELP
Sbjct: 361 GPLEYVPSAKVEVVEERQAIPLDENEGIYVQDVKTGKVRAVIGSTYMLTQDEVLWEKELP 420

Query: 421 PGVEELLNKGQDPLADRGEKDTAKSLQPLAPRNKTRVVSYRVPHNAAVQVYDYREKRARV 480
           PGVEELLNKGQDPLADRGEKDTAKSLQPLAPRNKTRVVSYRVPHNAAVQVYDYREKRARV
Sbjct: 421 PGVEELLNKGQDPLADRGEKDTAKSLQPLAPRNKTRVVSYRVPHNAAVQVYDYREKRARV 480

Query: 481 VFGPELVSLGPEEQFTVLSLSAGRPKRPHARRALCLLLGPDFFTDVITIETADHARLQLQ 540
           VFGPELVSLGPEEQFTVLSLSAGRPKRPHARRALCLLLGPDFFTDVITIETADHARLQLQ
Sbjct: 481 VFGPELVSLGPEEQFTVLSLSAGRPKRPHARRALCLLLGPDFFTDVITIETADHARLQLQ 540

Query: 541 LAYNWHFEVNDRKDPQETAKLFSVPDFVGDACKAIASRVRGAVASVTFDDFHKNSARIIR 600
           LAYNWHFEVNDRKDPQETAKLFSVPDFVGDACKAIASRVRGAVASVTFDDFHKNSARIIR
Sbjct: 541 LAYNWHFEVNDRKDPQETAKLFSVPDFVGDACKAIASRVRGAVASVTFDDFHKNSARIIR 600

Query: 601 TAVFGFETSEAKGPDGMALPRPRDQAVFPQNGLVVSSVDVQSVEPVDQRTRDALQRSVQL 660
           TAVFGFETSEAKGPDGMALPRPRDQAVFPQNGLVVSSVDVQSVEPVDQRTRDALQRSVQL
Sbjct: 601 TAVFGFETSEAKGPDGMALPRPRDQAVFPQNGLVVSSVDVQSVEPVDQRTRDALQRSVQL 660

Query: 661 AIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTG 720
           AIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTG
Sbjct: 661 AIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTG 720

Query: 721 TAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELE 780
           TAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELE
Sbjct: 721 TAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELE 780

Query: 781 VSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLKSTLITDGSTPIN 840
           VSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLKSTLITDGSTPIN
Sbjct: 781 VSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLKSTLITDGSTPIN 840

Query: 841 LFNTAFGLLGMGPEGQPLGRRVASGPSPGEGISPQSAQAPQAPGDNHVVPVLR 893
           LFNTAFGLLGMGPEGQPLGRRVASGPSPGEGISPQSAQAPQAPGDNHVVPVLR
Sbjct: 841 LFNTAFGLLGMGPEGQPLGRRVASGPSPGEGISPQSAQAPQAPGDNHVVPVLR 893


>gi|19913412 major vault protein [Homo sapiens]
          Length = 893

 Score = 1753 bits (4541), Expect = 0.0
 Identities = 893/893 (100%), Positives = 893/893 (100%)

Query: 1   MATEEFIIRIPPYHYIHVLDQNSNVSRVEVGPKTYIRQDNERVLFAPMRMVTVPPRHYCT 60
           MATEEFIIRIPPYHYIHVLDQNSNVSRVEVGPKTYIRQDNERVLFAPMRMVTVPPRHYCT
Sbjct: 1   MATEEFIIRIPPYHYIHVLDQNSNVSRVEVGPKTYIRQDNERVLFAPMRMVTVPPRHYCT 60

Query: 61  VANPVSRDAQGLVLFDVTGQVRLRHADLEIRLAQDPFPLYPGEVLEKDITPLQVVLPNTA 120
           VANPVSRDAQGLVLFDVTGQVRLRHADLEIRLAQDPFPLYPGEVLEKDITPLQVVLPNTA
Sbjct: 61  VANPVSRDAQGLVLFDVTGQVRLRHADLEIRLAQDPFPLYPGEVLEKDITPLQVVLPNTA 120

Query: 121 LHLKALLDFEDKDGDKVVAGDEWLFEGPGTYIPRKEVEVVEIIQATIIRQNQALRLRARK 180
           LHLKALLDFEDKDGDKVVAGDEWLFEGPGTYIPRKEVEVVEIIQATIIRQNQALRLRARK
Sbjct: 121 LHLKALLDFEDKDGDKVVAGDEWLFEGPGTYIPRKEVEVVEIIQATIIRQNQALRLRARK 180

Query: 181 ECWDRDGKERVTGEEWLVTTVGAYLPAVFEEVLDLVDAVILTEKTALHLRARRNFRDFRG 240
           ECWDRDGKERVTGEEWLVTTVGAYLPAVFEEVLDLVDAVILTEKTALHLRARRNFRDFRG
Sbjct: 181 ECWDRDGKERVTGEEWLVTTVGAYLPAVFEEVLDLVDAVILTEKTALHLRARRNFRDFRG 240

Query: 241 VSRRTGEEWLVTVQDTEAHVPDVHEEVLGVVPITTLGPHNYCVILDPVGPDGKNQLGQKR 300
           VSRRTGEEWLVTVQDTEAHVPDVHEEVLGVVPITTLGPHNYCVILDPVGPDGKNQLGQKR
Sbjct: 241 VSRRTGEEWLVTVQDTEAHVPDVHEEVLGVVPITTLGPHNYCVILDPVGPDGKNQLGQKR 300

Query: 301 VVKGEKSFFLQPGEQLEQGIQDVYVLSEQQGLLLRALQPLEEGEDEEKVSHQAGDHWLIR 360
           VVKGEKSFFLQPGEQLEQGIQDVYVLSEQQGLLLRALQPLEEGEDEEKVSHQAGDHWLIR
Sbjct: 301 VVKGEKSFFLQPGEQLEQGIQDVYVLSEQQGLLLRALQPLEEGEDEEKVSHQAGDHWLIR 360

Query: 361 GPLEYVPSAKVEVVEERQAIPLDENEGIYVQDVKTGKVRAVIGSTYMLTQDEVLWEKELP 420
           GPLEYVPSAKVEVVEERQAIPLDENEGIYVQDVKTGKVRAVIGSTYMLTQDEVLWEKELP
Sbjct: 361 GPLEYVPSAKVEVVEERQAIPLDENEGIYVQDVKTGKVRAVIGSTYMLTQDEVLWEKELP 420

Query: 421 PGVEELLNKGQDPLADRGEKDTAKSLQPLAPRNKTRVVSYRVPHNAAVQVYDYREKRARV 480
           PGVEELLNKGQDPLADRGEKDTAKSLQPLAPRNKTRVVSYRVPHNAAVQVYDYREKRARV
Sbjct: 421 PGVEELLNKGQDPLADRGEKDTAKSLQPLAPRNKTRVVSYRVPHNAAVQVYDYREKRARV 480

Query: 481 VFGPELVSLGPEEQFTVLSLSAGRPKRPHARRALCLLLGPDFFTDVITIETADHARLQLQ 540
           VFGPELVSLGPEEQFTVLSLSAGRPKRPHARRALCLLLGPDFFTDVITIETADHARLQLQ
Sbjct: 481 VFGPELVSLGPEEQFTVLSLSAGRPKRPHARRALCLLLGPDFFTDVITIETADHARLQLQ 540

Query: 541 LAYNWHFEVNDRKDPQETAKLFSVPDFVGDACKAIASRVRGAVASVTFDDFHKNSARIIR 600
           LAYNWHFEVNDRKDPQETAKLFSVPDFVGDACKAIASRVRGAVASVTFDDFHKNSARIIR
Sbjct: 541 LAYNWHFEVNDRKDPQETAKLFSVPDFVGDACKAIASRVRGAVASVTFDDFHKNSARIIR 600

Query: 601 TAVFGFETSEAKGPDGMALPRPRDQAVFPQNGLVVSSVDVQSVEPVDQRTRDALQRSVQL 660
           TAVFGFETSEAKGPDGMALPRPRDQAVFPQNGLVVSSVDVQSVEPVDQRTRDALQRSVQL
Sbjct: 601 TAVFGFETSEAKGPDGMALPRPRDQAVFPQNGLVVSSVDVQSVEPVDQRTRDALQRSVQL 660

Query: 661 AIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTG 720
           AIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTG
Sbjct: 661 AIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTG 720

Query: 721 TAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELE 780
           TAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELE
Sbjct: 721 TAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELE 780

Query: 781 VSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLKSTLITDGSTPIN 840
           VSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLKSTLITDGSTPIN
Sbjct: 781 VSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLKSTLITDGSTPIN 840

Query: 841 LFNTAFGLLGMGPEGQPLGRRVASGPSPGEGISPQSAQAPQAPGDNHVVPVLR 893
           LFNTAFGLLGMGPEGQPLGRRVASGPSPGEGISPQSAQAPQAPGDNHVVPVLR
Sbjct: 841 LFNTAFGLLGMGPEGQPLGRRVASGPSPGEGISPQSAQAPQAPGDNHVVPVLR 893


>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
          Length = 4547

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 43/152 (28%), Positives = 76/152 (50%), Gaps = 13/152 (8%)

Query: 648  QRTRDALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKEL 706
            Q+    LQ+++Q    +    + EA A   A    +EAR + ER       EA ++R+++
Sbjct: 2059 QQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER-------EAAQSRRQV 2111

Query: 707  LELEALSMAVESTGTAKAEAESRAEAARIEGEGSV---LQAKLKAQALAIETEAELQRVQ 763
             E E L  + E    A+A+A++ AE  R E E       QA+  A       +AE+++ +
Sbjct: 2112 EEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHK 2171

Query: 764  KVRELELVYARAQLELEVSKAQ-QLAEVEVKK 794
            K  E + +  +AQ+E E++  + QL E + +K
Sbjct: 2172 KFAE-QTLRQKAQVEQELTTLRLQLEETDHQK 2202



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 41/154 (26%), Positives = 65/154 (42%), Gaps = 28/154 (18%)

Query: 669  QEAAAKHEAQRLEQEA------RGRLERQKILDQSEAEKARKELLELEALSMAVESTGTA 722
            Q++ A+ EA++ ++EA      RG+ E Q +  +  AE+      ELE      E T   
Sbjct: 1654 QKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQ------ELEKQRQLAEGTAQQ 1707

Query: 723  KAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEV- 781
            +  AE      R E E    Q +L  + LA          QK +ELE   A+ + E+EV 
Sbjct: 1708 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL 1767

Query: 782  ---------------SKAQQLAEVEVKKFKQMTE 800
                            K++Q  E E  +F+++ E
Sbjct: 1768 LASKARAEEESRSTSEKSKQRLEAEAGRFRELAE 1801



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 50/159 (31%), Positives = 75/159 (47%), Gaps = 8/159 (5%)

Query: 648  QRTRDALQRS-VQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQ----SEAEKA 702
            + T  A QRS V+  +       E  +K +A R+E E R  + R K   Q     EAEK 
Sbjct: 2215 EATEAARQRSQVEEELFSVRVQMEELSKLKA-RIEAENRALILRDKDNTQRFLQEEAEKM 2273

Query: 703  RKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRV 762
            ++   E   LS+A +     +  AE      R   E  +L+ K++A   A   +AE + +
Sbjct: 2274 KQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAE-KMLKEKMQAVQEATRLKAEAELL 2332

Query: 763  QKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEA 801
            Q+ +EL    AR   E +   AQQLAE E + F++  EA
Sbjct: 2333 QQQKELAQEQARRLQEDKEQMAQQLAE-ETQGFQRTLEA 2370



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 49/189 (25%), Positives = 85/189 (44%), Gaps = 33/189 (17%)

Query: 644  EPVDQRTRDALQRSVQLAIEITTNSQEA--AAKHEAQRLEQEARGRLERQKILDQSE--- 698
            E  + + R A + + +L  ++   SQ    A    A R++ EA    E+Q+ L   E   
Sbjct: 1483 EEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELR 1542

Query: 699  --AEKARKELLELEA-----LSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQAL 751
              AE+A + L + E      + +A+E T    AEAE +++ A    + + L+  L+ + +
Sbjct: 1543 LQAEEAERRLRQAEVERARQVQVALE-TAQRSAEAELQSKRASFAEKTAQLERSLQEEHV 1601

Query: 752  AI-------------ETEAELQRVQKVRELELVYARAQLEL-------EVSKAQQLAEVE 791
            A+             + EAE  R +  RELE    +A   L       EV++ + LA+ E
Sbjct: 1602 AVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAE 1661

Query: 792  VKKFKQMTE 800
             +K K+  E
Sbjct: 1662 AEKQKEEAE 1670



 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 42/156 (26%), Positives = 76/156 (48%), Gaps = 15/156 (9%)

Query: 647  DQRTRDALQR-SVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKE 705
            ++R R+A +R    LA E     Q  AA  E +RL+ +     E +++ +++E E AR+ 
Sbjct: 1980 ERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVE---EARRLRERAEQESARQL 2036

Query: 706  LLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKL-KAQALAIETEAELQRVQK 764
             L  EA           + +AE +A A  ++ +   LQ  L + Q++  +   E +  ++
Sbjct: 2037 QLAQEA--------AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARR 2088

Query: 765  VRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTE 800
              E E   AR Q E E +++++  E E ++ KQ  E
Sbjct: 2089 AAE-EAEEARVQAEREAAQSRRQVE-EAERLKQSAE 2122



 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 48/170 (28%), Positives = 81/170 (47%), Gaps = 19/170 (11%)

Query: 641  QSVEPVDQRTR-----DALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILD 695
            + ++ V + TR     + LQ+  +LA E     QE   +  AQ+L +E +G    Q+ L 
Sbjct: 2314 EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDK-EQMAQQLAEETQGF---QRTL- 2368

Query: 696  QSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIET 755
              EAE+ R+  +  EA  + +     ++A+A +  +A R   +   +  KL    LA + 
Sbjct: 2369 --EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQE 2426

Query: 756  EA------ELQRVQKVRELE-LVYARAQLELEVSKAQQLAEVEVKKFKQM 798
            +       E+QR Q   + E L  A A+LE E  K QQ A++   K ++M
Sbjct: 2427 KVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM 2476



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 41/140 (29%), Positives = 67/140 (47%), Gaps = 11/140 (7%)

Query: 653  ALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEA 711
            AL++  QLA     ++Q +A A+ EA+ L+Q  +  + R++       ++ R    EL+ 
Sbjct: 1368 ALEKQRQLA---EAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQ 1424

Query: 712  LSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELV 771
            L  + E+   AKA     AE +R+  E  +   +L+ +A       E QR     EL+ +
Sbjct: 1425 LRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA------TERQRGGAEGELQAL 1478

Query: 772  YARAQLELEVSKAQQLAEVE 791
             ARA+ E E  K Q   E E
Sbjct: 1479 RARAE-EAEAQKRQAQEEAE 1497



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 47/169 (27%), Positives = 76/169 (44%), Gaps = 13/169 (7%)

Query: 669  QEAAAKHEAQ------RLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTA 722
            +E AA+H+A       +L + +   LERQK L +    + R+   E+ AL  + E     
Sbjct: 1881 EEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAG 1940

Query: 723  KAEAESRAEAARIEGEGSVL---QAKLKAQALAIETEAELQRVQKVRELELVYARAQLEL 779
            KAE E      R   E ++    QA+L+A A   +  AE +R ++  E E V      E 
Sbjct: 1941 KAELELELGRIRSNAEDTLRSKEQAELEA-ARQRQLAAEEERRRREAE-ERVQKSLAAEE 1998

Query: 780  EVSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLK 828
            E ++ ++ A  EV++ K   E      +R+ A      Q++L Q    K
Sbjct: 1999 EAARQRKAALEEVERLKAKVEE--ARRLRERAEQESARQLQLAQEAAQK 2045



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 46/155 (29%), Positives = 70/155 (45%), Gaps = 14/155 (9%)

Query: 648  QRTRDALQ--RSVQLAIEITTNSQEAA-----AKHEAQRLEQEARGRLERQKILDQSEAE 700
            Q  R+A Q  R V+ A  +  +++E A     A+  A++L +EA     R+   +Q+   
Sbjct: 2099 QAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALR 2158

Query: 701  KARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQAL----AIETE 756
            + +    E+E      E T   KA+ E      R++ E +  Q  L  + L    A  TE
Sbjct: 2159 QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATE 2218

Query: 757  AELQRVQKVRELELVYARAQLELEVSKAQQLAEVE 791
            A  QR Q   E EL   R Q+E E+SK +   E E
Sbjct: 2219 AARQRSQV--EEELFSVRVQME-ELSKLKARIEAE 2250



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 43/179 (24%), Positives = 84/179 (46%), Gaps = 20/179 (11%)

Query: 641  QSVEPVDQRTRDALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEA 699
            +++E   QR  +    + +L + +   S+ +A A+ +AQR  ++A    E+    + +  
Sbjct: 2366 RTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQ 2425

Query: 700  EKARK-ELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAE 758
            EK    + LE++      ++    +A AE   E  +++ E  +LQ K + +   ++ E  
Sbjct: 2426 EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSE-EMQTVQQEQL 2484

Query: 759  LQRVQKV-------------RELELVYARAQLEL----EVSKAQQLAEVEVKKFKQMTE 800
            LQ  Q +             RE  +   +A+LE     EV+KAQQL E + ++ +QM +
Sbjct: 2485 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQ 2543



 Score = 38.1 bits (87), Expect = 0.037
 Identities = 43/180 (23%), Positives = 87/180 (48%), Gaps = 23/180 (12%)

Query: 662  IEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGT 721
            +E +   +  A     +  E+ A+ + E ++  +++E E  R +L   EAL + +++   
Sbjct: 1592 LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEV 1651

Query: 722  AKAEAESRAEAARIEGEGS-VLQAKLKAQALAI-ETEAELQRVQKVREL----------- 768
            A+ ++ ++AEA + + E     + + KA+  A+ + E   Q ++K R+L           
Sbjct: 1652 AQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAA 1711

Query: 769  --ELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAIGPSTIR-----DLAVAGPEMQVKL 821
              EL+  RA+ E +  + +QL E E+ + ++  EA   +  R     +LA    EM+V L
Sbjct: 1712 EQELIRLRAETE-QGEQQRQLLEEELARLQR--EAAAATQKRQELEAELAKVRAEMEVLL 1768



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 26/120 (21%), Positives = 56/120 (46%), Gaps = 4/120 (3%)

Query: 683  EARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVL 742
            E   R+E ++ L + +  + R+ L E+EA          A A+A+++AE    E +  + 
Sbjct: 1339 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1398

Query: 743  QAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAI 802
            +  ++ +  A++ + + + +Q+    EL   R   E E+    + AE   +   ++ E I
Sbjct: 1399 EEVVRREEAAVDAQQQKRSIQE----ELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEI 1454


>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
          Length = 4551

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 43/152 (28%), Positives = 76/152 (50%), Gaps = 13/152 (8%)

Query: 648  QRTRDALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKEL 706
            Q+    LQ+++Q    +    + EA A   A    +EAR + ER       EA ++R+++
Sbjct: 2063 QQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER-------EAAQSRRQV 2115

Query: 707  LELEALSMAVESTGTAKAEAESRAEAARIEGEGSV---LQAKLKAQALAIETEAELQRVQ 763
             E E L  + E    A+A+A++ AE  R E E       QA+  A       +AE+++ +
Sbjct: 2116 EEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHK 2175

Query: 764  KVRELELVYARAQLELEVSKAQ-QLAEVEVKK 794
            K  E + +  +AQ+E E++  + QL E + +K
Sbjct: 2176 KFAE-QTLRQKAQVEQELTTLRLQLEETDHQK 2206



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 41/154 (26%), Positives = 65/154 (42%), Gaps = 28/154 (18%)

Query: 669  QEAAAKHEAQRLEQEA------RGRLERQKILDQSEAEKARKELLELEALSMAVESTGTA 722
            Q++ A+ EA++ ++EA      RG+ E Q +  +  AE+      ELE      E T   
Sbjct: 1658 QKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQ------ELEKQRQLAEGTAQQ 1711

Query: 723  KAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEV- 781
            +  AE      R E E    Q +L  + LA          QK +ELE   A+ + E+EV 
Sbjct: 1712 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL 1771

Query: 782  ---------------SKAQQLAEVEVKKFKQMTE 800
                            K++Q  E E  +F+++ E
Sbjct: 1772 LASKARAEEESRSTSEKSKQRLEAEAGRFRELAE 1805



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 50/159 (31%), Positives = 75/159 (47%), Gaps = 8/159 (5%)

Query: 648  QRTRDALQRS-VQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQ----SEAEKA 702
            + T  A QRS V+  +       E  +K +A R+E E R  + R K   Q     EAEK 
Sbjct: 2219 EATEAARQRSQVEEELFSVRVQMEELSKLKA-RIEAENRALILRDKDNTQRFLQEEAEKM 2277

Query: 703  RKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRV 762
            ++   E   LS+A +     +  AE      R   E  +L+ K++A   A   +AE + +
Sbjct: 2278 KQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAE-KMLKEKMQAVQEATRLKAEAELL 2336

Query: 763  QKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEA 801
            Q+ +EL    AR   E +   AQQLAE E + F++  EA
Sbjct: 2337 QQQKELAQEQARRLQEDKEQMAQQLAE-ETQGFQRTLEA 2374



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 49/189 (25%), Positives = 85/189 (44%), Gaps = 33/189 (17%)

Query: 644  EPVDQRTRDALQRSVQLAIEITTNSQEA--AAKHEAQRLEQEARGRLERQKILDQSE--- 698
            E  + + R A + + +L  ++   SQ    A    A R++ EA    E+Q+ L   E   
Sbjct: 1487 EEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELR 1546

Query: 699  --AEKARKELLELEA-----LSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQAL 751
              AE+A + L + E      + +A+E T    AEAE +++ A    + + L+  L+ + +
Sbjct: 1547 LQAEEAERRLRQAEVERARQVQVALE-TAQRSAEAELQSKRASFAEKTAQLERSLQEEHV 1605

Query: 752  AI-------------ETEAELQRVQKVRELELVYARAQLEL-------EVSKAQQLAEVE 791
            A+             + EAE  R +  RELE    +A   L       EV++ + LA+ E
Sbjct: 1606 AVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAE 1665

Query: 792  VKKFKQMTE 800
             +K K+  E
Sbjct: 1666 AEKQKEEAE 1674



 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 42/156 (26%), Positives = 76/156 (48%), Gaps = 15/156 (9%)

Query: 647  DQRTRDALQR-SVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKE 705
            ++R R+A +R    LA E     Q  AA  E +RL+ +     E +++ +++E E AR+ 
Sbjct: 1984 ERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVE---EARRLRERAEQESARQL 2040

Query: 706  LLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKL-KAQALAIETEAELQRVQK 764
             L  EA           + +AE +A A  ++ +   LQ  L + Q++  +   E +  ++
Sbjct: 2041 QLAQEA--------AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARR 2092

Query: 765  VRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTE 800
              E E   AR Q E E +++++  E E ++ KQ  E
Sbjct: 2093 AAE-EAEEARVQAEREAAQSRRQVE-EAERLKQSAE 2126



 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 48/170 (28%), Positives = 81/170 (47%), Gaps = 19/170 (11%)

Query: 641  QSVEPVDQRTR-----DALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILD 695
            + ++ V + TR     + LQ+  +LA E     QE   +  AQ+L +E +G    Q+ L 
Sbjct: 2318 EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDK-EQMAQQLAEETQGF---QRTL- 2372

Query: 696  QSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIET 755
              EAE+ R+  +  EA  + +     ++A+A +  +A R   +   +  KL    LA + 
Sbjct: 2373 --EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQE 2430

Query: 756  EA------ELQRVQKVRELE-LVYARAQLELEVSKAQQLAEVEVKKFKQM 798
            +       E+QR Q   + E L  A A+LE E  K QQ A++   K ++M
Sbjct: 2431 KVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM 2480



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 41/140 (29%), Positives = 67/140 (47%), Gaps = 11/140 (7%)

Query: 653  ALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEA 711
            AL++  QLA     ++Q +A A+ EA+ L+Q  +  + R++       ++ R    EL+ 
Sbjct: 1372 ALEKQRQLA---EAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQ 1428

Query: 712  LSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELV 771
            L  + E+   AKA     AE +R+  E  +   +L+ +A       E QR     EL+ +
Sbjct: 1429 LRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA------TERQRGGAEGELQAL 1482

Query: 772  YARAQLELEVSKAQQLAEVE 791
             ARA+ E E  K Q   E E
Sbjct: 1483 RARAE-EAEAQKRQAQEEAE 1501



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 47/169 (27%), Positives = 76/169 (44%), Gaps = 13/169 (7%)

Query: 669  QEAAAKHEAQ------RLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTA 722
            +E AA+H+A       +L + +   LERQK L +    + R+   E+ AL  + E     
Sbjct: 1885 EEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAG 1944

Query: 723  KAEAESRAEAARIEGEGSVL---QAKLKAQALAIETEAELQRVQKVRELELVYARAQLEL 779
            KAE E      R   E ++    QA+L+A A   +  AE +R ++  E E V      E 
Sbjct: 1945 KAELELELGRIRSNAEDTLRSKEQAELEA-ARQRQLAAEEERRRREAE-ERVQKSLAAEE 2002

Query: 780  EVSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLK 828
            E ++ ++ A  EV++ K   E      +R+ A      Q++L Q    K
Sbjct: 2003 EAARQRKAALEEVERLKAKVEE--ARRLRERAEQESARQLQLAQEAAQK 2049



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 46/155 (29%), Positives = 70/155 (45%), Gaps = 14/155 (9%)

Query: 648  QRTRDALQ--RSVQLAIEITTNSQEAA-----AKHEAQRLEQEARGRLERQKILDQSEAE 700
            Q  R+A Q  R V+ A  +  +++E A     A+  A++L +EA     R+   +Q+   
Sbjct: 2103 QAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALR 2162

Query: 701  KARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQAL----AIETE 756
            + +    E+E      E T   KA+ E      R++ E +  Q  L  + L    A  TE
Sbjct: 2163 QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATE 2222

Query: 757  AELQRVQKVRELELVYARAQLELEVSKAQQLAEVE 791
            A  QR Q   E EL   R Q+E E+SK +   E E
Sbjct: 2223 AARQRSQV--EEELFSVRVQME-ELSKLKARIEAE 2254



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 43/179 (24%), Positives = 84/179 (46%), Gaps = 20/179 (11%)

Query: 641  QSVEPVDQRTRDALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEA 699
            +++E   QR  +    + +L + +   S+ +A A+ +AQR  ++A    E+    + +  
Sbjct: 2370 RTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQ 2429

Query: 700  EKARK-ELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAE 758
            EK    + LE++      ++    +A AE   E  +++ E  +LQ K + +   ++ E  
Sbjct: 2430 EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSE-EMQTVQQEQL 2488

Query: 759  LQRVQKV-------------RELELVYARAQLEL----EVSKAQQLAEVEVKKFKQMTE 800
            LQ  Q +             RE  +   +A+LE     EV+KAQQL E + ++ +QM +
Sbjct: 2489 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQ 2547



 Score = 38.1 bits (87), Expect = 0.037
 Identities = 43/180 (23%), Positives = 87/180 (48%), Gaps = 23/180 (12%)

Query: 662  IEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGT 721
            +E +   +  A     +  E+ A+ + E ++  +++E E  R +L   EAL + +++   
Sbjct: 1596 LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEV 1655

Query: 722  AKAEAESRAEAARIEGEGS-VLQAKLKAQALAI-ETEAELQRVQKVREL----------- 768
            A+ ++ ++AEA + + E     + + KA+  A+ + E   Q ++K R+L           
Sbjct: 1656 AQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAA 1715

Query: 769  --ELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAIGPSTIR-----DLAVAGPEMQVKL 821
              EL+  RA+ E +  + +QL E E+ + ++  EA   +  R     +LA    EM+V L
Sbjct: 1716 EQELIRLRAETE-QGEQQRQLLEEELARLQR--EAAAATQKRQELEAELAKVRAEMEVLL 1772



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 26/120 (21%), Positives = 56/120 (46%), Gaps = 4/120 (3%)

Query: 683  EARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVL 742
            E   R+E ++ L + +  + R+ L E+EA          A A+A+++AE    E +  + 
Sbjct: 1343 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1402

Query: 743  QAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAI 802
            +  ++ +  A++ + + + +Q+    EL   R   E E+    + AE   +   ++ E I
Sbjct: 1403 EEVVRREEAAVDAQQQKRSIQE----ELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEI 1458


>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
          Length = 4547

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 43/152 (28%), Positives = 76/152 (50%), Gaps = 13/152 (8%)

Query: 648  QRTRDALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKEL 706
            Q+    LQ+++Q    +    + EA A   A    +EAR + ER       EA ++R+++
Sbjct: 2059 QQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER-------EAAQSRRQV 2111

Query: 707  LELEALSMAVESTGTAKAEAESRAEAARIEGEGSV---LQAKLKAQALAIETEAELQRVQ 763
             E E L  + E    A+A+A++ AE  R E E       QA+  A       +AE+++ +
Sbjct: 2112 EEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHK 2171

Query: 764  KVRELELVYARAQLELEVSKAQ-QLAEVEVKK 794
            K  E + +  +AQ+E E++  + QL E + +K
Sbjct: 2172 KFAE-QTLRQKAQVEQELTTLRLQLEETDHQK 2202



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 41/154 (26%), Positives = 65/154 (42%), Gaps = 28/154 (18%)

Query: 669  QEAAAKHEAQRLEQEA------RGRLERQKILDQSEAEKARKELLELEALSMAVESTGTA 722
            Q++ A+ EA++ ++EA      RG+ E Q +  +  AE+      ELE      E T   
Sbjct: 1654 QKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQ------ELEKQRQLAEGTAQQ 1707

Query: 723  KAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEV- 781
            +  AE      R E E    Q +L  + LA          QK +ELE   A+ + E+EV 
Sbjct: 1708 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL 1767

Query: 782  ---------------SKAQQLAEVEVKKFKQMTE 800
                            K++Q  E E  +F+++ E
Sbjct: 1768 LASKARAEEESRSTSEKSKQRLEAEAGRFRELAE 1801



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 50/159 (31%), Positives = 75/159 (47%), Gaps = 8/159 (5%)

Query: 648  QRTRDALQRS-VQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQ----SEAEKA 702
            + T  A QRS V+  +       E  +K +A R+E E R  + R K   Q     EAEK 
Sbjct: 2215 EATEAARQRSQVEEELFSVRVQMEELSKLKA-RIEAENRALILRDKDNTQRFLQEEAEKM 2273

Query: 703  RKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRV 762
            ++   E   LS+A +     +  AE      R   E  +L+ K++A   A   +AE + +
Sbjct: 2274 KQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAE-KMLKEKMQAVQEATRLKAEAELL 2332

Query: 763  QKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEA 801
            Q+ +EL    AR   E +   AQQLAE E + F++  EA
Sbjct: 2333 QQQKELAQEQARRLQEDKEQMAQQLAE-ETQGFQRTLEA 2370



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 49/189 (25%), Positives = 85/189 (44%), Gaps = 33/189 (17%)

Query: 644  EPVDQRTRDALQRSVQLAIEITTNSQEA--AAKHEAQRLEQEARGRLERQKILDQSE--- 698
            E  + + R A + + +L  ++   SQ    A    A R++ EA    E+Q+ L   E   
Sbjct: 1483 EEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELR 1542

Query: 699  --AEKARKELLELEA-----LSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQAL 751
              AE+A + L + E      + +A+E T    AEAE +++ A    + + L+  L+ + +
Sbjct: 1543 LQAEEAERRLRQAEVERARQVQVALE-TAQRSAEAELQSKRASFAEKTAQLERSLQEEHV 1601

Query: 752  AI-------------ETEAELQRVQKVRELELVYARAQLEL-------EVSKAQQLAEVE 791
            A+             + EAE  R +  RELE    +A   L       EV++ + LA+ E
Sbjct: 1602 AVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAE 1661

Query: 792  VKKFKQMTE 800
             +K K+  E
Sbjct: 1662 AEKQKEEAE 1670



 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 42/156 (26%), Positives = 76/156 (48%), Gaps = 15/156 (9%)

Query: 647  DQRTRDALQR-SVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKE 705
            ++R R+A +R    LA E     Q  AA  E +RL+ +     E +++ +++E E AR+ 
Sbjct: 1980 ERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVE---EARRLRERAEQESARQL 2036

Query: 706  LLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKL-KAQALAIETEAELQRVQK 764
             L  EA           + +AE +A A  ++ +   LQ  L + Q++  +   E +  ++
Sbjct: 2037 QLAQEA--------AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARR 2088

Query: 765  VRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTE 800
              E E   AR Q E E +++++  E E ++ KQ  E
Sbjct: 2089 AAE-EAEEARVQAEREAAQSRRQVE-EAERLKQSAE 2122



 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 48/170 (28%), Positives = 81/170 (47%), Gaps = 19/170 (11%)

Query: 641  QSVEPVDQRTR-----DALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILD 695
            + ++ V + TR     + LQ+  +LA E     QE   +  AQ+L +E +G    Q+ L 
Sbjct: 2314 EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDK-EQMAQQLAEETQGF---QRTL- 2368

Query: 696  QSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIET 755
              EAE+ R+  +  EA  + +     ++A+A +  +A R   +   +  KL    LA + 
Sbjct: 2369 --EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQE 2426

Query: 756  EA------ELQRVQKVRELE-LVYARAQLELEVSKAQQLAEVEVKKFKQM 798
            +       E+QR Q   + E L  A A+LE E  K QQ A++   K ++M
Sbjct: 2427 KVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM 2476



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 41/140 (29%), Positives = 67/140 (47%), Gaps = 11/140 (7%)

Query: 653  ALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEA 711
            AL++  QLA     ++Q +A A+ EA+ L+Q  +  + R++       ++ R    EL+ 
Sbjct: 1368 ALEKQRQLA---EAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQ 1424

Query: 712  LSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELV 771
            L  + E+   AKA     AE +R+  E  +   +L+ +A       E QR     EL+ +
Sbjct: 1425 LRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA------TERQRGGAEGELQAL 1478

Query: 772  YARAQLELEVSKAQQLAEVE 791
             ARA+ E E  K Q   E E
Sbjct: 1479 RARAE-EAEAQKRQAQEEAE 1497



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 47/169 (27%), Positives = 76/169 (44%), Gaps = 13/169 (7%)

Query: 669  QEAAAKHEAQ------RLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTA 722
            +E AA+H+A       +L + +   LERQK L +    + R+   E+ AL  + E     
Sbjct: 1881 EEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAG 1940

Query: 723  KAEAESRAEAARIEGEGSVL---QAKLKAQALAIETEAELQRVQKVRELELVYARAQLEL 779
            KAE E      R   E ++    QA+L+A A   +  AE +R ++  E E V      E 
Sbjct: 1941 KAELELELGRIRSNAEDTLRSKEQAELEA-ARQRQLAAEEERRRREAE-ERVQKSLAAEE 1998

Query: 780  EVSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLK 828
            E ++ ++ A  EV++ K   E      +R+ A      Q++L Q    K
Sbjct: 1999 EAARQRKAALEEVERLKAKVEE--ARRLRERAEQESARQLQLAQEAAQK 2045



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 46/155 (29%), Positives = 70/155 (45%), Gaps = 14/155 (9%)

Query: 648  QRTRDALQ--RSVQLAIEITTNSQEAA-----AKHEAQRLEQEARGRLERQKILDQSEAE 700
            Q  R+A Q  R V+ A  +  +++E A     A+  A++L +EA     R+   +Q+   
Sbjct: 2099 QAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALR 2158

Query: 701  KARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQAL----AIETE 756
            + +    E+E      E T   KA+ E      R++ E +  Q  L  + L    A  TE
Sbjct: 2159 QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATE 2218

Query: 757  AELQRVQKVRELELVYARAQLELEVSKAQQLAEVE 791
            A  QR Q   E EL   R Q+E E+SK +   E E
Sbjct: 2219 AARQRSQV--EEELFSVRVQME-ELSKLKARIEAE 2250



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 43/179 (24%), Positives = 84/179 (46%), Gaps = 20/179 (11%)

Query: 641  QSVEPVDQRTRDALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEA 699
            +++E   QR  +    + +L + +   S+ +A A+ +AQR  ++A    E+    + +  
Sbjct: 2366 RTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQ 2425

Query: 700  EKARK-ELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAE 758
            EK    + LE++      ++    +A AE   E  +++ E  +LQ K + +   ++ E  
Sbjct: 2426 EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSE-EMQTVQQEQL 2484

Query: 759  LQRVQKV-------------RELELVYARAQLEL----EVSKAQQLAEVEVKKFKQMTE 800
            LQ  Q +             RE  +   +A+LE     EV+KAQQL E + ++ +QM +
Sbjct: 2485 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQ 2543



 Score = 38.1 bits (87), Expect = 0.037
 Identities = 43/180 (23%), Positives = 87/180 (48%), Gaps = 23/180 (12%)

Query: 662  IEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGT 721
            +E +   +  A     +  E+ A+ + E ++  +++E E  R +L   EAL + +++   
Sbjct: 1592 LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEV 1651

Query: 722  AKAEAESRAEAARIEGEGS-VLQAKLKAQALAI-ETEAELQRVQKVREL----------- 768
            A+ ++ ++AEA + + E     + + KA+  A+ + E   Q ++K R+L           
Sbjct: 1652 AQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAA 1711

Query: 769  --ELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAIGPSTIR-----DLAVAGPEMQVKL 821
              EL+  RA+ E +  + +QL E E+ + ++  EA   +  R     +LA    EM+V L
Sbjct: 1712 EQELIRLRAETE-QGEQQRQLLEEELARLQR--EAAAATQKRQELEAELAKVRAEMEVLL 1768



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 26/120 (21%), Positives = 56/120 (46%), Gaps = 4/120 (3%)

Query: 683  EARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVL 742
            E   R+E ++ L + +  + R+ L E+EA          A A+A+++AE    E +  + 
Sbjct: 1339 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1398

Query: 743  QAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAI 802
            +  ++ +  A++ + + + +Q+    EL   R   E E+    + AE   +   ++ E I
Sbjct: 1399 EEVVRREEAAVDAQQQKRSIQE----ELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEI 1454


>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
          Length = 4515

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 43/152 (28%), Positives = 76/152 (50%), Gaps = 13/152 (8%)

Query: 648  QRTRDALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKEL 706
            Q+    LQ+++Q    +    + EA A   A    +EAR + ER       EA ++R+++
Sbjct: 2027 QQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER-------EAAQSRRQV 2079

Query: 707  LELEALSMAVESTGTAKAEAESRAEAARIEGEGSV---LQAKLKAQALAIETEAELQRVQ 763
             E E L  + E    A+A+A++ AE  R E E       QA+  A       +AE+++ +
Sbjct: 2080 EEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHK 2139

Query: 764  KVRELELVYARAQLELEVSKAQ-QLAEVEVKK 794
            K  E + +  +AQ+E E++  + QL E + +K
Sbjct: 2140 KFAE-QTLRQKAQVEQELTTLRLQLEETDHQK 2170



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 41/154 (26%), Positives = 65/154 (42%), Gaps = 28/154 (18%)

Query: 669  QEAAAKHEAQRLEQEA------RGRLERQKILDQSEAEKARKELLELEALSMAVESTGTA 722
            Q++ A+ EA++ ++EA      RG+ E Q +  +  AE+      ELE      E T   
Sbjct: 1622 QKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQ------ELEKQRQLAEGTAQQ 1675

Query: 723  KAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEV- 781
            +  AE      R E E    Q +L  + LA          QK +ELE   A+ + E+EV 
Sbjct: 1676 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL 1735

Query: 782  ---------------SKAQQLAEVEVKKFKQMTE 800
                            K++Q  E E  +F+++ E
Sbjct: 1736 LASKARAEEESRSTSEKSKQRLEAEAGRFRELAE 1769



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 50/159 (31%), Positives = 75/159 (47%), Gaps = 8/159 (5%)

Query: 648  QRTRDALQRS-VQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQ----SEAEKA 702
            + T  A QRS V+  +       E  +K +A R+E E R  + R K   Q     EAEK 
Sbjct: 2183 EATEAARQRSQVEEELFSVRVQMEELSKLKA-RIEAENRALILRDKDNTQRFLQEEAEKM 2241

Query: 703  RKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRV 762
            ++   E   LS+A +     +  AE      R   E  +L+ K++A   A   +AE + +
Sbjct: 2242 KQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAE-KMLKEKMQAVQEATRLKAEAELL 2300

Query: 763  QKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEA 801
            Q+ +EL    AR   E +   AQQLAE E + F++  EA
Sbjct: 2301 QQQKELAQEQARRLQEDKEQMAQQLAE-ETQGFQRTLEA 2338



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 49/189 (25%), Positives = 85/189 (44%), Gaps = 33/189 (17%)

Query: 644  EPVDQRTRDALQRSVQLAIEITTNSQEA--AAKHEAQRLEQEARGRLERQKILDQSE--- 698
            E  + + R A + + +L  ++   SQ    A    A R++ EA    E+Q+ L   E   
Sbjct: 1451 EEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELR 1510

Query: 699  --AEKARKELLELEA-----LSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQAL 751
              AE+A + L + E      + +A+E T    AEAE +++ A    + + L+  L+ + +
Sbjct: 1511 LQAEEAERRLRQAEVERARQVQVALE-TAQRSAEAELQSKRASFAEKTAQLERSLQEEHV 1569

Query: 752  AI-------------ETEAELQRVQKVRELELVYARAQLEL-------EVSKAQQLAEVE 791
            A+             + EAE  R +  RELE    +A   L       EV++ + LA+ E
Sbjct: 1570 AVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAE 1629

Query: 792  VKKFKQMTE 800
             +K K+  E
Sbjct: 1630 AEKQKEEAE 1638



 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 42/156 (26%), Positives = 76/156 (48%), Gaps = 15/156 (9%)

Query: 647  DQRTRDALQR-SVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKE 705
            ++R R+A +R    LA E     Q  AA  E +RL+ +     E +++ +++E E AR+ 
Sbjct: 1948 ERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVE---EARRLRERAEQESARQL 2004

Query: 706  LLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKL-KAQALAIETEAELQRVQK 764
             L  EA           + +AE +A A  ++ +   LQ  L + Q++  +   E +  ++
Sbjct: 2005 QLAQEA--------AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARR 2056

Query: 765  VRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTE 800
              E E   AR Q E E +++++  E E ++ KQ  E
Sbjct: 2057 AAE-EAEEARVQAEREAAQSRRQVE-EAERLKQSAE 2090



 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 48/170 (28%), Positives = 81/170 (47%), Gaps = 19/170 (11%)

Query: 641  QSVEPVDQRTR-----DALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILD 695
            + ++ V + TR     + LQ+  +LA E     QE   +  AQ+L +E +G    Q+ L 
Sbjct: 2282 EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDK-EQMAQQLAEETQGF---QRTL- 2336

Query: 696  QSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIET 755
              EAE+ R+  +  EA  + +     ++A+A +  +A R   +   +  KL    LA + 
Sbjct: 2337 --EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQE 2394

Query: 756  EA------ELQRVQKVRELE-LVYARAQLELEVSKAQQLAEVEVKKFKQM 798
            +       E+QR Q   + E L  A A+LE E  K QQ A++   K ++M
Sbjct: 2395 KVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM 2444



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 41/140 (29%), Positives = 67/140 (47%), Gaps = 11/140 (7%)

Query: 653  ALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEA 711
            AL++  QLA     ++Q +A A+ EA+ L+Q  +  + R++       ++ R    EL+ 
Sbjct: 1336 ALEKQRQLA---EAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQ 1392

Query: 712  LSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELV 771
            L  + E+   AKA     AE +R+  E  +   +L+ +A       E QR     EL+ +
Sbjct: 1393 LRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA------TERQRGGAEGELQAL 1446

Query: 772  YARAQLELEVSKAQQLAEVE 791
             ARA+ E E  K Q   E E
Sbjct: 1447 RARAE-EAEAQKRQAQEEAE 1465



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 47/169 (27%), Positives = 76/169 (44%), Gaps = 13/169 (7%)

Query: 669  QEAAAKHEAQ------RLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTA 722
            +E AA+H+A       +L + +   LERQK L +    + R+   E+ AL  + E     
Sbjct: 1849 EEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAG 1908

Query: 723  KAEAESRAEAARIEGEGSVL---QAKLKAQALAIETEAELQRVQKVRELELVYARAQLEL 779
            KAE E      R   E ++    QA+L+A A   +  AE +R ++  E E V      E 
Sbjct: 1909 KAELELELGRIRSNAEDTLRSKEQAELEA-ARQRQLAAEEERRRREAE-ERVQKSLAAEE 1966

Query: 780  EVSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLK 828
            E ++ ++ A  EV++ K   E      +R+ A      Q++L Q    K
Sbjct: 1967 EAARQRKAALEEVERLKAKVEE--ARRLRERAEQESARQLQLAQEAAQK 2013



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 46/155 (29%), Positives = 70/155 (45%), Gaps = 14/155 (9%)

Query: 648  QRTRDALQ--RSVQLAIEITTNSQEAA-----AKHEAQRLEQEARGRLERQKILDQSEAE 700
            Q  R+A Q  R V+ A  +  +++E A     A+  A++L +EA     R+   +Q+   
Sbjct: 2067 QAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALR 2126

Query: 701  KARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQAL----AIETE 756
            + +    E+E      E T   KA+ E      R++ E +  Q  L  + L    A  TE
Sbjct: 2127 QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATE 2186

Query: 757  AELQRVQKVRELELVYARAQLELEVSKAQQLAEVE 791
            A  QR Q   E EL   R Q+E E+SK +   E E
Sbjct: 2187 AARQRSQV--EEELFSVRVQME-ELSKLKARIEAE 2218



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 43/179 (24%), Positives = 84/179 (46%), Gaps = 20/179 (11%)

Query: 641  QSVEPVDQRTRDALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEA 699
            +++E   QR  +    + +L + +   S+ +A A+ +AQR  ++A    E+    + +  
Sbjct: 2334 RTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQ 2393

Query: 700  EKARK-ELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAE 758
            EK    + LE++      ++    +A AE   E  +++ E  +LQ K + +   ++ E  
Sbjct: 2394 EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSE-EMQTVQQEQL 2452

Query: 759  LQRVQKV-------------RELELVYARAQLEL----EVSKAQQLAEVEVKKFKQMTE 800
            LQ  Q +             RE  +   +A+LE     EV+KAQQL E + ++ +QM +
Sbjct: 2453 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQ 2511



 Score = 38.1 bits (87), Expect = 0.037
 Identities = 43/180 (23%), Positives = 87/180 (48%), Gaps = 23/180 (12%)

Query: 662  IEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGT 721
            +E +   +  A     +  E+ A+ + E ++  +++E E  R +L   EAL + +++   
Sbjct: 1560 LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEV 1619

Query: 722  AKAEAESRAEAARIEGEGS-VLQAKLKAQALAI-ETEAELQRVQKVREL----------- 768
            A+ ++ ++AEA + + E     + + KA+  A+ + E   Q ++K R+L           
Sbjct: 1620 AQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAA 1679

Query: 769  --ELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAIGPSTIR-----DLAVAGPEMQVKL 821
              EL+  RA+ E +  + +QL E E+ + ++  EA   +  R     +LA    EM+V L
Sbjct: 1680 EQELIRLRAETE-QGEQQRQLLEEELARLQR--EAAAATQKRQELEAELAKVRAEMEVLL 1736



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 26/120 (21%), Positives = 56/120 (46%), Gaps = 4/120 (3%)

Query: 683  EARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVL 742
            E   R+E ++ L + +  + R+ L E+EA          A A+A+++AE    E +  + 
Sbjct: 1307 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1366

Query: 743  QAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAI 802
            +  ++ +  A++ + + + +Q+    EL   R   E E+    + AE   +   ++ E I
Sbjct: 1367 EEVVRREEAAVDAQQQKRSIQE----ELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEI 1422


>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
          Length = 4684

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 43/152 (28%), Positives = 76/152 (50%), Gaps = 13/152 (8%)

Query: 648  QRTRDALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKEL 706
            Q+    LQ+++Q    +    + EA A   A    +EAR + ER       EA ++R+++
Sbjct: 2196 QQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER-------EAAQSRRQV 2248

Query: 707  LELEALSMAVESTGTAKAEAESRAEAARIEGEGSV---LQAKLKAQALAIETEAELQRVQ 763
             E E L  + E    A+A+A++ AE  R E E       QA+  A       +AE+++ +
Sbjct: 2249 EEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHK 2308

Query: 764  KVRELELVYARAQLELEVSKAQ-QLAEVEVKK 794
            K  E + +  +AQ+E E++  + QL E + +K
Sbjct: 2309 KFAE-QTLRQKAQVEQELTTLRLQLEETDHQK 2339



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 41/154 (26%), Positives = 65/154 (42%), Gaps = 28/154 (18%)

Query: 669  QEAAAKHEAQRLEQEA------RGRLERQKILDQSEAEKARKELLELEALSMAVESTGTA 722
            Q++ A+ EA++ ++EA      RG+ E Q +  +  AE+      ELE      E T   
Sbjct: 1791 QKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQ------ELEKQRQLAEGTAQQ 1844

Query: 723  KAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEV- 781
            +  AE      R E E    Q +L  + LA          QK +ELE   A+ + E+EV 
Sbjct: 1845 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL 1904

Query: 782  ---------------SKAQQLAEVEVKKFKQMTE 800
                            K++Q  E E  +F+++ E
Sbjct: 1905 LASKARAEEESRSTSEKSKQRLEAEAGRFRELAE 1938



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 50/159 (31%), Positives = 75/159 (47%), Gaps = 8/159 (5%)

Query: 648  QRTRDALQRS-VQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQ----SEAEKA 702
            + T  A QRS V+  +       E  +K +A R+E E R  + R K   Q     EAEK 
Sbjct: 2352 EATEAARQRSQVEEELFSVRVQMEELSKLKA-RIEAENRALILRDKDNTQRFLQEEAEKM 2410

Query: 703  RKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRV 762
            ++   E   LS+A +     +  AE      R   E  +L+ K++A   A   +AE + +
Sbjct: 2411 KQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAE-KMLKEKMQAVQEATRLKAEAELL 2469

Query: 763  QKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEA 801
            Q+ +EL    AR   E +   AQQLAE E + F++  EA
Sbjct: 2470 QQQKELAQEQARRLQEDKEQMAQQLAE-ETQGFQRTLEA 2507



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 49/189 (25%), Positives = 85/189 (44%), Gaps = 33/189 (17%)

Query: 644  EPVDQRTRDALQRSVQLAIEITTNSQEA--AAKHEAQRLEQEARGRLERQKILDQSE--- 698
            E  + + R A + + +L  ++   SQ    A    A R++ EA    E+Q+ L   E   
Sbjct: 1620 EEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELR 1679

Query: 699  --AEKARKELLELEA-----LSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQAL 751
              AE+A + L + E      + +A+E T    AEAE +++ A    + + L+  L+ + +
Sbjct: 1680 LQAEEAERRLRQAEVERARQVQVALE-TAQRSAEAELQSKRASFAEKTAQLERSLQEEHV 1738

Query: 752  AI-------------ETEAELQRVQKVRELELVYARAQLEL-------EVSKAQQLAEVE 791
            A+             + EAE  R +  RELE    +A   L       EV++ + LA+ E
Sbjct: 1739 AVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAE 1798

Query: 792  VKKFKQMTE 800
             +K K+  E
Sbjct: 1799 AEKQKEEAE 1807



 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 42/156 (26%), Positives = 76/156 (48%), Gaps = 15/156 (9%)

Query: 647  DQRTRDALQR-SVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKE 705
            ++R R+A +R    LA E     Q  AA  E +RL+ +     E +++ +++E E AR+ 
Sbjct: 2117 ERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVE---EARRLRERAEQESARQL 2173

Query: 706  LLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKL-KAQALAIETEAELQRVQK 764
             L  EA           + +AE +A A  ++ +   LQ  L + Q++  +   E +  ++
Sbjct: 2174 QLAQEA--------AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARR 2225

Query: 765  VRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTE 800
              E E   AR Q E E +++++  E E ++ KQ  E
Sbjct: 2226 AAE-EAEEARVQAEREAAQSRRQVE-EAERLKQSAE 2259



 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 48/170 (28%), Positives = 81/170 (47%), Gaps = 19/170 (11%)

Query: 641  QSVEPVDQRTR-----DALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILD 695
            + ++ V + TR     + LQ+  +LA E     QE   +  AQ+L +E +G    Q+ L 
Sbjct: 2451 EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDK-EQMAQQLAEETQGF---QRTL- 2505

Query: 696  QSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIET 755
              EAE+ R+  +  EA  + +     ++A+A +  +A R   +   +  KL    LA + 
Sbjct: 2506 --EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQE 2563

Query: 756  EA------ELQRVQKVRELE-LVYARAQLELEVSKAQQLAEVEVKKFKQM 798
            +       E+QR Q   + E L  A A+LE E  K QQ A++   K ++M
Sbjct: 2564 KVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM 2613



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 41/140 (29%), Positives = 67/140 (47%), Gaps = 11/140 (7%)

Query: 653  ALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEA 711
            AL++  QLA     ++Q +A A+ EA+ L+Q  +  + R++       ++ R    EL+ 
Sbjct: 1505 ALEKQRQLA---EAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQ 1561

Query: 712  LSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELV 771
            L  + E+   AKA     AE +R+  E  +   +L+ +A       E QR     EL+ +
Sbjct: 1562 LRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA------TERQRGGAEGELQAL 1615

Query: 772  YARAQLELEVSKAQQLAEVE 791
             ARA+ E E  K Q   E E
Sbjct: 1616 RARAE-EAEAQKRQAQEEAE 1634



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 47/169 (27%), Positives = 76/169 (44%), Gaps = 13/169 (7%)

Query: 669  QEAAAKHEAQ------RLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTA 722
            +E AA+H+A       +L + +   LERQK L +    + R+   E+ AL  + E     
Sbjct: 2018 EEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAG 2077

Query: 723  KAEAESRAEAARIEGEGSVL---QAKLKAQALAIETEAELQRVQKVRELELVYARAQLEL 779
            KAE E      R   E ++    QA+L+A A   +  AE +R ++  E E V      E 
Sbjct: 2078 KAELELELGRIRSNAEDTLRSKEQAELEA-ARQRQLAAEEERRRREAE-ERVQKSLAAEE 2135

Query: 780  EVSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLK 828
            E ++ ++ A  EV++ K   E      +R+ A      Q++L Q    K
Sbjct: 2136 EAARQRKAALEEVERLKAKVEE--ARRLRERAEQESARQLQLAQEAAQK 2182



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 46/155 (29%), Positives = 70/155 (45%), Gaps = 14/155 (9%)

Query: 648  QRTRDALQ--RSVQLAIEITTNSQEAA-----AKHEAQRLEQEARGRLERQKILDQSEAE 700
            Q  R+A Q  R V+ A  +  +++E A     A+  A++L +EA     R+   +Q+   
Sbjct: 2236 QAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALR 2295

Query: 701  KARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQAL----AIETE 756
            + +    E+E      E T   KA+ E      R++ E +  Q  L  + L    A  TE
Sbjct: 2296 QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATE 2355

Query: 757  AELQRVQKVRELELVYARAQLELEVSKAQQLAEVE 791
            A  QR Q   E EL   R Q+E E+SK +   E E
Sbjct: 2356 AARQRSQV--EEELFSVRVQME-ELSKLKARIEAE 2387



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 43/179 (24%), Positives = 84/179 (46%), Gaps = 20/179 (11%)

Query: 641  QSVEPVDQRTRDALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEA 699
            +++E   QR  +    + +L + +   S+ +A A+ +AQR  ++A    E+    + +  
Sbjct: 2503 RTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQ 2562

Query: 700  EKARK-ELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAE 758
            EK    + LE++      ++    +A AE   E  +++ E  +LQ K + +   ++ E  
Sbjct: 2563 EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSE-EMQTVQQEQL 2621

Query: 759  LQRVQKV-------------RELELVYARAQLEL----EVSKAQQLAEVEVKKFKQMTE 800
            LQ  Q +             RE  +   +A+LE     EV+KAQQL E + ++ +QM +
Sbjct: 2622 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQ 2680



 Score = 38.1 bits (87), Expect = 0.037
 Identities = 43/180 (23%), Positives = 87/180 (48%), Gaps = 23/180 (12%)

Query: 662  IEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGT 721
            +E +   +  A     +  E+ A+ + E ++  +++E E  R +L   EAL + +++   
Sbjct: 1729 LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEV 1788

Query: 722  AKAEAESRAEAARIEGEGS-VLQAKLKAQALAI-ETEAELQRVQKVREL----------- 768
            A+ ++ ++AEA + + E     + + KA+  A+ + E   Q ++K R+L           
Sbjct: 1789 AQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAA 1848

Query: 769  --ELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAIGPSTIR-----DLAVAGPEMQVKL 821
              EL+  RA+ E +  + +QL E E+ + ++  EA   +  R     +LA    EM+V L
Sbjct: 1849 EQELIRLRAETE-QGEQQRQLLEEELARLQR--EAAAATQKRQELEAELAKVRAEMEVLL 1905



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 26/120 (21%), Positives = 56/120 (46%), Gaps = 4/120 (3%)

Query: 683  EARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVL 742
            E   R+E ++ L + +  + R+ L E+EA          A A+A+++AE    E +  + 
Sbjct: 1476 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1535

Query: 743  QAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAI 802
            +  ++ +  A++ + + + +Q+    EL   R   E E+    + AE   +   ++ E I
Sbjct: 1536 EEVVRREEAAVDAQQQKRSIQE----ELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEI 1591


>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
          Length = 4525

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 43/152 (28%), Positives = 76/152 (50%), Gaps = 13/152 (8%)

Query: 648  QRTRDALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKEL 706
            Q+    LQ+++Q    +    + EA A   A    +EAR + ER       EA ++R+++
Sbjct: 2037 QQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER-------EAAQSRRQV 2089

Query: 707  LELEALSMAVESTGTAKAEAESRAEAARIEGEGSV---LQAKLKAQALAIETEAELQRVQ 763
             E E L  + E    A+A+A++ AE  R E E       QA+  A       +AE+++ +
Sbjct: 2090 EEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHK 2149

Query: 764  KVRELELVYARAQLELEVSKAQ-QLAEVEVKK 794
            K  E + +  +AQ+E E++  + QL E + +K
Sbjct: 2150 KFAE-QTLRQKAQVEQELTTLRLQLEETDHQK 2180



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 41/154 (26%), Positives = 65/154 (42%), Gaps = 28/154 (18%)

Query: 669  QEAAAKHEAQRLEQEA------RGRLERQKILDQSEAEKARKELLELEALSMAVESTGTA 722
            Q++ A+ EA++ ++EA      RG+ E Q +  +  AE+      ELE      E T   
Sbjct: 1632 QKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQ------ELEKQRQLAEGTAQQ 1685

Query: 723  KAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEV- 781
            +  AE      R E E    Q +L  + LA          QK +ELE   A+ + E+EV 
Sbjct: 1686 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL 1745

Query: 782  ---------------SKAQQLAEVEVKKFKQMTE 800
                            K++Q  E E  +F+++ E
Sbjct: 1746 LASKARAEEESRSTSEKSKQRLEAEAGRFRELAE 1779



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 50/159 (31%), Positives = 75/159 (47%), Gaps = 8/159 (5%)

Query: 648  QRTRDALQRS-VQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQ----SEAEKA 702
            + T  A QRS V+  +       E  +K +A R+E E R  + R K   Q     EAEK 
Sbjct: 2193 EATEAARQRSQVEEELFSVRVQMEELSKLKA-RIEAENRALILRDKDNTQRFLQEEAEKM 2251

Query: 703  RKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRV 762
            ++   E   LS+A +     +  AE      R   E  +L+ K++A   A   +AE + +
Sbjct: 2252 KQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAE-KMLKEKMQAVQEATRLKAEAELL 2310

Query: 763  QKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEA 801
            Q+ +EL    AR   E +   AQQLAE E + F++  EA
Sbjct: 2311 QQQKELAQEQARRLQEDKEQMAQQLAE-ETQGFQRTLEA 2348



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 49/189 (25%), Positives = 85/189 (44%), Gaps = 33/189 (17%)

Query: 644  EPVDQRTRDALQRSVQLAIEITTNSQEA--AAKHEAQRLEQEARGRLERQKILDQSE--- 698
            E  + + R A + + +L  ++   SQ    A    A R++ EA    E+Q+ L   E   
Sbjct: 1461 EEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELR 1520

Query: 699  --AEKARKELLELEA-----LSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQAL 751
              AE+A + L + E      + +A+E T    AEAE +++ A    + + L+  L+ + +
Sbjct: 1521 LQAEEAERRLRQAEVERARQVQVALE-TAQRSAEAELQSKRASFAEKTAQLERSLQEEHV 1579

Query: 752  AI-------------ETEAELQRVQKVRELELVYARAQLEL-------EVSKAQQLAEVE 791
            A+             + EAE  R +  RELE    +A   L       EV++ + LA+ E
Sbjct: 1580 AVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAE 1639

Query: 792  VKKFKQMTE 800
             +K K+  E
Sbjct: 1640 AEKQKEEAE 1648



 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 42/156 (26%), Positives = 76/156 (48%), Gaps = 15/156 (9%)

Query: 647  DQRTRDALQR-SVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKE 705
            ++R R+A +R    LA E     Q  AA  E +RL+ +     E +++ +++E E AR+ 
Sbjct: 1958 ERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVE---EARRLRERAEQESARQL 2014

Query: 706  LLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKL-KAQALAIETEAELQRVQK 764
             L  EA           + +AE +A A  ++ +   LQ  L + Q++  +   E +  ++
Sbjct: 2015 QLAQEA--------AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARR 2066

Query: 765  VRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTE 800
              E E   AR Q E E +++++  E E ++ KQ  E
Sbjct: 2067 AAE-EAEEARVQAEREAAQSRRQVE-EAERLKQSAE 2100



 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 48/170 (28%), Positives = 81/170 (47%), Gaps = 19/170 (11%)

Query: 641  QSVEPVDQRTR-----DALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILD 695
            + ++ V + TR     + LQ+  +LA E     QE   +  AQ+L +E +G    Q+ L 
Sbjct: 2292 EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDK-EQMAQQLAEETQGF---QRTL- 2346

Query: 696  QSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIET 755
              EAE+ R+  +  EA  + +     ++A+A +  +A R   +   +  KL    LA + 
Sbjct: 2347 --EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQE 2404

Query: 756  EA------ELQRVQKVRELE-LVYARAQLELEVSKAQQLAEVEVKKFKQM 798
            +       E+QR Q   + E L  A A+LE E  K QQ A++   K ++M
Sbjct: 2405 KVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM 2454



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 41/140 (29%), Positives = 67/140 (47%), Gaps = 11/140 (7%)

Query: 653  ALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEA 711
            AL++  QLA     ++Q +A A+ EA+ L+Q  +  + R++       ++ R    EL+ 
Sbjct: 1346 ALEKQRQLA---EAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQ 1402

Query: 712  LSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELV 771
            L  + E+   AKA     AE +R+  E  +   +L+ +A       E QR     EL+ +
Sbjct: 1403 LRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA------TERQRGGAEGELQAL 1456

Query: 772  YARAQLELEVSKAQQLAEVE 791
             ARA+ E E  K Q   E E
Sbjct: 1457 RARAE-EAEAQKRQAQEEAE 1475



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 47/169 (27%), Positives = 76/169 (44%), Gaps = 13/169 (7%)

Query: 669  QEAAAKHEAQ------RLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTA 722
            +E AA+H+A       +L + +   LERQK L +    + R+   E+ AL  + E     
Sbjct: 1859 EEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAG 1918

Query: 723  KAEAESRAEAARIEGEGSVL---QAKLKAQALAIETEAELQRVQKVRELELVYARAQLEL 779
            KAE E      R   E ++    QA+L+A A   +  AE +R ++  E E V      E 
Sbjct: 1919 KAELELELGRIRSNAEDTLRSKEQAELEA-ARQRQLAAEEERRRREAE-ERVQKSLAAEE 1976

Query: 780  EVSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLK 828
            E ++ ++ A  EV++ K   E      +R+ A      Q++L Q    K
Sbjct: 1977 EAARQRKAALEEVERLKAKVEE--ARRLRERAEQESARQLQLAQEAAQK 2023



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 46/155 (29%), Positives = 70/155 (45%), Gaps = 14/155 (9%)

Query: 648  QRTRDALQ--RSVQLAIEITTNSQEAA-----AKHEAQRLEQEARGRLERQKILDQSEAE 700
            Q  R+A Q  R V+ A  +  +++E A     A+  A++L +EA     R+   +Q+   
Sbjct: 2077 QAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALR 2136

Query: 701  KARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQAL----AIETE 756
            + +    E+E      E T   KA+ E      R++ E +  Q  L  + L    A  TE
Sbjct: 2137 QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATE 2196

Query: 757  AELQRVQKVRELELVYARAQLELEVSKAQQLAEVE 791
            A  QR Q   E EL   R Q+E E+SK +   E E
Sbjct: 2197 AARQRSQV--EEELFSVRVQME-ELSKLKARIEAE 2228



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 43/179 (24%), Positives = 84/179 (46%), Gaps = 20/179 (11%)

Query: 641  QSVEPVDQRTRDALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEA 699
            +++E   QR  +    + +L + +   S+ +A A+ +AQR  ++A    E+    + +  
Sbjct: 2344 RTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQ 2403

Query: 700  EKARK-ELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAE 758
            EK    + LE++      ++    +A AE   E  +++ E  +LQ K + +   ++ E  
Sbjct: 2404 EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSE-EMQTVQQEQL 2462

Query: 759  LQRVQKV-------------RELELVYARAQLEL----EVSKAQQLAEVEVKKFKQMTE 800
            LQ  Q +             RE  +   +A+LE     EV+KAQQL E + ++ +QM +
Sbjct: 2463 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQ 2521



 Score = 38.1 bits (87), Expect = 0.037
 Identities = 43/180 (23%), Positives = 87/180 (48%), Gaps = 23/180 (12%)

Query: 662  IEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGT 721
            +E +   +  A     +  E+ A+ + E ++  +++E E  R +L   EAL + +++   
Sbjct: 1570 LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEV 1629

Query: 722  AKAEAESRAEAARIEGEGS-VLQAKLKAQALAI-ETEAELQRVQKVREL----------- 768
            A+ ++ ++AEA + + E     + + KA+  A+ + E   Q ++K R+L           
Sbjct: 1630 AQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAA 1689

Query: 769  --ELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAIGPSTIR-----DLAVAGPEMQVKL 821
              EL+  RA+ E +  + +QL E E+ + ++  EA   +  R     +LA    EM+V L
Sbjct: 1690 EQELIRLRAETE-QGEQQRQLLEEELARLQR--EAAAATQKRQELEAELAKVRAEMEVLL 1746



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 26/120 (21%), Positives = 56/120 (46%), Gaps = 4/120 (3%)

Query: 683  EARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVL 742
            E   R+E ++ L + +  + R+ L E+EA          A A+A+++AE    E +  + 
Sbjct: 1317 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1376

Query: 743  QAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAI 802
            +  ++ +  A++ + + + +Q+    EL   R   E E+    + AE   +   ++ E I
Sbjct: 1377 EEVVRREEAAVDAQQQKRSIQE----ELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEI 1432


>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
          Length = 4533

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 43/152 (28%), Positives = 76/152 (50%), Gaps = 13/152 (8%)

Query: 648  QRTRDALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKEL 706
            Q+    LQ+++Q    +    + EA A   A    +EAR + ER       EA ++R+++
Sbjct: 2045 QQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER-------EAAQSRRQV 2097

Query: 707  LELEALSMAVESTGTAKAEAESRAEAARIEGEGSV---LQAKLKAQALAIETEAELQRVQ 763
             E E L  + E    A+A+A++ AE  R E E       QA+  A       +AE+++ +
Sbjct: 2098 EEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHK 2157

Query: 764  KVRELELVYARAQLELEVSKAQ-QLAEVEVKK 794
            K  E + +  +AQ+E E++  + QL E + +K
Sbjct: 2158 KFAE-QTLRQKAQVEQELTTLRLQLEETDHQK 2188



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 41/154 (26%), Positives = 65/154 (42%), Gaps = 28/154 (18%)

Query: 669  QEAAAKHEAQRLEQEA------RGRLERQKILDQSEAEKARKELLELEALSMAVESTGTA 722
            Q++ A+ EA++ ++EA      RG+ E Q +  +  AE+      ELE      E T   
Sbjct: 1640 QKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQ------ELEKQRQLAEGTAQQ 1693

Query: 723  KAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEV- 781
            +  AE      R E E    Q +L  + LA          QK +ELE   A+ + E+EV 
Sbjct: 1694 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL 1753

Query: 782  ---------------SKAQQLAEVEVKKFKQMTE 800
                            K++Q  E E  +F+++ E
Sbjct: 1754 LASKARAEEESRSTSEKSKQRLEAEAGRFRELAE 1787



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 50/159 (31%), Positives = 75/159 (47%), Gaps = 8/159 (5%)

Query: 648  QRTRDALQRS-VQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQ----SEAEKA 702
            + T  A QRS V+  +       E  +K +A R+E E R  + R K   Q     EAEK 
Sbjct: 2201 EATEAARQRSQVEEELFSVRVQMEELSKLKA-RIEAENRALILRDKDNTQRFLQEEAEKM 2259

Query: 703  RKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRV 762
            ++   E   LS+A +     +  AE      R   E  +L+ K++A   A   +AE + +
Sbjct: 2260 KQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAE-KMLKEKMQAVQEATRLKAEAELL 2318

Query: 763  QKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEA 801
            Q+ +EL    AR   E +   AQQLAE E + F++  EA
Sbjct: 2319 QQQKELAQEQARRLQEDKEQMAQQLAE-ETQGFQRTLEA 2356



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 49/189 (25%), Positives = 85/189 (44%), Gaps = 33/189 (17%)

Query: 644  EPVDQRTRDALQRSVQLAIEITTNSQEA--AAKHEAQRLEQEARGRLERQKILDQSE--- 698
            E  + + R A + + +L  ++   SQ    A    A R++ EA    E+Q+ L   E   
Sbjct: 1469 EEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELR 1528

Query: 699  --AEKARKELLELEA-----LSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQAL 751
              AE+A + L + E      + +A+E T    AEAE +++ A    + + L+  L+ + +
Sbjct: 1529 LQAEEAERRLRQAEVERARQVQVALE-TAQRSAEAELQSKRASFAEKTAQLERSLQEEHV 1587

Query: 752  AI-------------ETEAELQRVQKVRELELVYARAQLEL-------EVSKAQQLAEVE 791
            A+             + EAE  R +  RELE    +A   L       EV++ + LA+ E
Sbjct: 1588 AVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAE 1647

Query: 792  VKKFKQMTE 800
             +K K+  E
Sbjct: 1648 AEKQKEEAE 1656



 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 42/156 (26%), Positives = 76/156 (48%), Gaps = 15/156 (9%)

Query: 647  DQRTRDALQR-SVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKE 705
            ++R R+A +R    LA E     Q  AA  E +RL+ +     E +++ +++E E AR+ 
Sbjct: 1966 ERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVE---EARRLRERAEQESARQL 2022

Query: 706  LLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKL-KAQALAIETEAELQRVQK 764
             L  EA           + +AE +A A  ++ +   LQ  L + Q++  +   E +  ++
Sbjct: 2023 QLAQEA--------AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARR 2074

Query: 765  VRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTE 800
              E E   AR Q E E +++++  E E ++ KQ  E
Sbjct: 2075 AAE-EAEEARVQAEREAAQSRRQVE-EAERLKQSAE 2108



 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 48/170 (28%), Positives = 81/170 (47%), Gaps = 19/170 (11%)

Query: 641  QSVEPVDQRTR-----DALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILD 695
            + ++ V + TR     + LQ+  +LA E     QE   +  AQ+L +E +G    Q+ L 
Sbjct: 2300 EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDK-EQMAQQLAEETQGF---QRTL- 2354

Query: 696  QSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIET 755
              EAE+ R+  +  EA  + +     ++A+A +  +A R   +   +  KL    LA + 
Sbjct: 2355 --EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQE 2412

Query: 756  EA------ELQRVQKVRELE-LVYARAQLELEVSKAQQLAEVEVKKFKQM 798
            +       E+QR Q   + E L  A A+LE E  K QQ A++   K ++M
Sbjct: 2413 KVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM 2462



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 41/140 (29%), Positives = 67/140 (47%), Gaps = 11/140 (7%)

Query: 653  ALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEA 711
            AL++  QLA     ++Q +A A+ EA+ L+Q  +  + R++       ++ R    EL+ 
Sbjct: 1354 ALEKQRQLA---EAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQ 1410

Query: 712  LSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELV 771
            L  + E+   AKA     AE +R+  E  +   +L+ +A       E QR     EL+ +
Sbjct: 1411 LRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA------TERQRGGAEGELQAL 1464

Query: 772  YARAQLELEVSKAQQLAEVE 791
             ARA+ E E  K Q   E E
Sbjct: 1465 RARAE-EAEAQKRQAQEEAE 1483



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 47/169 (27%), Positives = 76/169 (44%), Gaps = 13/169 (7%)

Query: 669  QEAAAKHEAQ------RLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTA 722
            +E AA+H+A       +L + +   LERQK L +    + R+   E+ AL  + E     
Sbjct: 1867 EEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAG 1926

Query: 723  KAEAESRAEAARIEGEGSVL---QAKLKAQALAIETEAELQRVQKVRELELVYARAQLEL 779
            KAE E      R   E ++    QA+L+A A   +  AE +R ++  E E V      E 
Sbjct: 1927 KAELELELGRIRSNAEDTLRSKEQAELEA-ARQRQLAAEEERRRREAE-ERVQKSLAAEE 1984

Query: 780  EVSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLK 828
            E ++ ++ A  EV++ K   E      +R+ A      Q++L Q    K
Sbjct: 1985 EAARQRKAALEEVERLKAKVEE--ARRLRERAEQESARQLQLAQEAAQK 2031



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 46/155 (29%), Positives = 70/155 (45%), Gaps = 14/155 (9%)

Query: 648  QRTRDALQ--RSVQLAIEITTNSQEAA-----AKHEAQRLEQEARGRLERQKILDQSEAE 700
            Q  R+A Q  R V+ A  +  +++E A     A+  A++L +EA     R+   +Q+   
Sbjct: 2085 QAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALR 2144

Query: 701  KARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQAL----AIETE 756
            + +    E+E      E T   KA+ E      R++ E +  Q  L  + L    A  TE
Sbjct: 2145 QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATE 2204

Query: 757  AELQRVQKVRELELVYARAQLELEVSKAQQLAEVE 791
            A  QR Q   E EL   R Q+E E+SK +   E E
Sbjct: 2205 AARQRSQV--EEELFSVRVQME-ELSKLKARIEAE 2236



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 43/179 (24%), Positives = 84/179 (46%), Gaps = 20/179 (11%)

Query: 641  QSVEPVDQRTRDALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEA 699
            +++E   QR  +    + +L + +   S+ +A A+ +AQR  ++A    E+    + +  
Sbjct: 2352 RTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQ 2411

Query: 700  EKARK-ELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAE 758
            EK    + LE++      ++    +A AE   E  +++ E  +LQ K + +   ++ E  
Sbjct: 2412 EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSE-EMQTVQQEQL 2470

Query: 759  LQRVQKV-------------RELELVYARAQLEL----EVSKAQQLAEVEVKKFKQMTE 800
            LQ  Q +             RE  +   +A+LE     EV+KAQQL E + ++ +QM +
Sbjct: 2471 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQ 2529



 Score = 38.1 bits (87), Expect = 0.037
 Identities = 43/180 (23%), Positives = 87/180 (48%), Gaps = 23/180 (12%)

Query: 662  IEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGT 721
            +E +   +  A     +  E+ A+ + E ++  +++E E  R +L   EAL + +++   
Sbjct: 1578 LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEV 1637

Query: 722  AKAEAESRAEAARIEGEGS-VLQAKLKAQALAI-ETEAELQRVQKVREL----------- 768
            A+ ++ ++AEA + + E     + + KA+  A+ + E   Q ++K R+L           
Sbjct: 1638 AQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAA 1697

Query: 769  --ELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAIGPSTIR-----DLAVAGPEMQVKL 821
              EL+  RA+ E +  + +QL E E+ + ++  EA   +  R     +LA    EM+V L
Sbjct: 1698 EQELIRLRAETE-QGEQQRQLLEEELARLQR--EAAAATQKRQELEAELAKVRAEMEVLL 1754



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 26/120 (21%), Positives = 56/120 (46%), Gaps = 4/120 (3%)

Query: 683  EARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVL 742
            E   R+E ++ L + +  + R+ L E+EA          A A+A+++AE    E +  + 
Sbjct: 1325 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1384

Query: 743  QAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAI 802
            +  ++ +  A++ + + + +Q+    EL   R   E E+    + AE   +   ++ E I
Sbjct: 1385 EEVVRREEAAVDAQQQKRSIQE----ELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEI 1440


>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
          Length = 4574

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 43/152 (28%), Positives = 76/152 (50%), Gaps = 13/152 (8%)

Query: 648  QRTRDALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKEL 706
            Q+    LQ+++Q    +    + EA A   A    +EAR + ER       EA ++R+++
Sbjct: 2086 QQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER-------EAAQSRRQV 2138

Query: 707  LELEALSMAVESTGTAKAEAESRAEAARIEGEGSV---LQAKLKAQALAIETEAELQRVQ 763
             E E L  + E    A+A+A++ AE  R E E       QA+  A       +AE+++ +
Sbjct: 2139 EEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHK 2198

Query: 764  KVRELELVYARAQLELEVSKAQ-QLAEVEVKK 794
            K  E + +  +AQ+E E++  + QL E + +K
Sbjct: 2199 KFAE-QTLRQKAQVEQELTTLRLQLEETDHQK 2229



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 41/154 (26%), Positives = 65/154 (42%), Gaps = 28/154 (18%)

Query: 669  QEAAAKHEAQRLEQEA------RGRLERQKILDQSEAEKARKELLELEALSMAVESTGTA 722
            Q++ A+ EA++ ++EA      RG+ E Q +  +  AE+      ELE      E T   
Sbjct: 1681 QKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQ------ELEKQRQLAEGTAQQ 1734

Query: 723  KAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEV- 781
            +  AE      R E E    Q +L  + LA          QK +ELE   A+ + E+EV 
Sbjct: 1735 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL 1794

Query: 782  ---------------SKAQQLAEVEVKKFKQMTE 800
                            K++Q  E E  +F+++ E
Sbjct: 1795 LASKARAEEESRSTSEKSKQRLEAEAGRFRELAE 1828



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 50/159 (31%), Positives = 75/159 (47%), Gaps = 8/159 (5%)

Query: 648  QRTRDALQRS-VQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQ----SEAEKA 702
            + T  A QRS V+  +       E  +K +A R+E E R  + R K   Q     EAEK 
Sbjct: 2242 EATEAARQRSQVEEELFSVRVQMEELSKLKA-RIEAENRALILRDKDNTQRFLQEEAEKM 2300

Query: 703  RKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRV 762
            ++   E   LS+A +     +  AE      R   E  +L+ K++A   A   +AE + +
Sbjct: 2301 KQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAE-KMLKEKMQAVQEATRLKAEAELL 2359

Query: 763  QKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEA 801
            Q+ +EL    AR   E +   AQQLAE E + F++  EA
Sbjct: 2360 QQQKELAQEQARRLQEDKEQMAQQLAE-ETQGFQRTLEA 2397



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 49/189 (25%), Positives = 85/189 (44%), Gaps = 33/189 (17%)

Query: 644  EPVDQRTRDALQRSVQLAIEITTNSQEA--AAKHEAQRLEQEARGRLERQKILDQSE--- 698
            E  + + R A + + +L  ++   SQ    A    A R++ EA    E+Q+ L   E   
Sbjct: 1510 EEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELR 1569

Query: 699  --AEKARKELLELEA-----LSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQAL 751
              AE+A + L + E      + +A+E T    AEAE +++ A    + + L+  L+ + +
Sbjct: 1570 LQAEEAERRLRQAEVERARQVQVALE-TAQRSAEAELQSKRASFAEKTAQLERSLQEEHV 1628

Query: 752  AI-------------ETEAELQRVQKVRELELVYARAQLEL-------EVSKAQQLAEVE 791
            A+             + EAE  R +  RELE    +A   L       EV++ + LA+ E
Sbjct: 1629 AVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAE 1688

Query: 792  VKKFKQMTE 800
             +K K+  E
Sbjct: 1689 AEKQKEEAE 1697



 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 42/156 (26%), Positives = 76/156 (48%), Gaps = 15/156 (9%)

Query: 647  DQRTRDALQR-SVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKE 705
            ++R R+A +R    LA E     Q  AA  E +RL+ +     E +++ +++E E AR+ 
Sbjct: 2007 ERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVE---EARRLRERAEQESARQL 2063

Query: 706  LLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKL-KAQALAIETEAELQRVQK 764
             L  EA           + +AE +A A  ++ +   LQ  L + Q++  +   E +  ++
Sbjct: 2064 QLAQEA--------AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARR 2115

Query: 765  VRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTE 800
              E E   AR Q E E +++++  E E ++ KQ  E
Sbjct: 2116 AAE-EAEEARVQAEREAAQSRRQVE-EAERLKQSAE 2149



 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 48/170 (28%), Positives = 81/170 (47%), Gaps = 19/170 (11%)

Query: 641  QSVEPVDQRTR-----DALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILD 695
            + ++ V + TR     + LQ+  +LA E     QE   +  AQ+L +E +G    Q+ L 
Sbjct: 2341 EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDK-EQMAQQLAEETQGF---QRTL- 2395

Query: 696  QSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIET 755
              EAE+ R+  +  EA  + +     ++A+A +  +A R   +   +  KL    LA + 
Sbjct: 2396 --EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQE 2453

Query: 756  EA------ELQRVQKVRELE-LVYARAQLELEVSKAQQLAEVEVKKFKQM 798
            +       E+QR Q   + E L  A A+LE E  K QQ A++   K ++M
Sbjct: 2454 KVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM 2503



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 41/140 (29%), Positives = 67/140 (47%), Gaps = 11/140 (7%)

Query: 653  ALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEA 711
            AL++  QLA     ++Q +A A+ EA+ L+Q  +  + R++       ++ R    EL+ 
Sbjct: 1395 ALEKQRQLA---EAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQ 1451

Query: 712  LSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELV 771
            L  + E+   AKA     AE +R+  E  +   +L+ +A       E QR     EL+ +
Sbjct: 1452 LRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA------TERQRGGAEGELQAL 1505

Query: 772  YARAQLELEVSKAQQLAEVE 791
             ARA+ E E  K Q   E E
Sbjct: 1506 RARAE-EAEAQKRQAQEEAE 1524



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 47/169 (27%), Positives = 76/169 (44%), Gaps = 13/169 (7%)

Query: 669  QEAAAKHEAQ------RLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTA 722
            +E AA+H+A       +L + +   LERQK L +    + R+   E+ AL  + E     
Sbjct: 1908 EEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAG 1967

Query: 723  KAEAESRAEAARIEGEGSVL---QAKLKAQALAIETEAELQRVQKVRELELVYARAQLEL 779
            KAE E      R   E ++    QA+L+A A   +  AE +R ++  E E V      E 
Sbjct: 1968 KAELELELGRIRSNAEDTLRSKEQAELEA-ARQRQLAAEEERRRREAE-ERVQKSLAAEE 2025

Query: 780  EVSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLK 828
            E ++ ++ A  EV++ K   E      +R+ A      Q++L Q    K
Sbjct: 2026 EAARQRKAALEEVERLKAKVEE--ARRLRERAEQESARQLQLAQEAAQK 2072



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 46/155 (29%), Positives = 70/155 (45%), Gaps = 14/155 (9%)

Query: 648  QRTRDALQ--RSVQLAIEITTNSQEAA-----AKHEAQRLEQEARGRLERQKILDQSEAE 700
            Q  R+A Q  R V+ A  +  +++E A     A+  A++L +EA     R+   +Q+   
Sbjct: 2126 QAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALR 2185

Query: 701  KARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQAL----AIETE 756
            + +    E+E      E T   KA+ E      R++ E +  Q  L  + L    A  TE
Sbjct: 2186 QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATE 2245

Query: 757  AELQRVQKVRELELVYARAQLELEVSKAQQLAEVE 791
            A  QR Q   E EL   R Q+E E+SK +   E E
Sbjct: 2246 AARQRSQV--EEELFSVRVQME-ELSKLKARIEAE 2277



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 43/179 (24%), Positives = 84/179 (46%), Gaps = 20/179 (11%)

Query: 641  QSVEPVDQRTRDALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEA 699
            +++E   QR  +    + +L + +   S+ +A A+ +AQR  ++A    E+    + +  
Sbjct: 2393 RTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQ 2452

Query: 700  EKARK-ELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAE 758
            EK    + LE++      ++    +A AE   E  +++ E  +LQ K + +   ++ E  
Sbjct: 2453 EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSE-EMQTVQQEQL 2511

Query: 759  LQRVQKV-------------RELELVYARAQLEL----EVSKAQQLAEVEVKKFKQMTE 800
            LQ  Q +             RE  +   +A+LE     EV+KAQQL E + ++ +QM +
Sbjct: 2512 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQ 2570



 Score = 38.1 bits (87), Expect = 0.037
 Identities = 43/180 (23%), Positives = 87/180 (48%), Gaps = 23/180 (12%)

Query: 662  IEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGT 721
            +E +   +  A     +  E+ A+ + E ++  +++E E  R +L   EAL + +++   
Sbjct: 1619 LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEV 1678

Query: 722  AKAEAESRAEAARIEGEGS-VLQAKLKAQALAI-ETEAELQRVQKVREL----------- 768
            A+ ++ ++AEA + + E     + + KA+  A+ + E   Q ++K R+L           
Sbjct: 1679 AQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAA 1738

Query: 769  --ELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAIGPSTIR-----DLAVAGPEMQVKL 821
              EL+  RA+ E +  + +QL E E+ + ++  EA   +  R     +LA    EM+V L
Sbjct: 1739 EQELIRLRAETE-QGEQQRQLLEEELARLQR--EAAAATQKRQELEAELAKVRAEMEVLL 1795



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 26/120 (21%), Positives = 56/120 (46%), Gaps = 4/120 (3%)

Query: 683  EARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVL 742
            E   R+E ++ L + +  + R+ L E+EA          A A+A+++AE    E +  + 
Sbjct: 1366 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1425

Query: 743  QAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAI 802
            +  ++ +  A++ + + + +Q+    EL   R   E E+    + AE   +   ++ E I
Sbjct: 1426 EEVVRREEAAVDAQQQKRSIQE----ELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEI 1481


>gi|94538362 flotillin 2 [Homo sapiens]
          Length = 428

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 40/125 (32%), Positives = 69/125 (55%), Gaps = 14/125 (11%)

Query: 652 DALQRSVQLAIE----ITTNSQEAA-----AKHEAQRLEQEARGRLERQKILDQSEAEKA 702
           + +QR  Q+A+E    + T+ +  A     A+ EA R++Q A G   +Q +L Q+EAEK 
Sbjct: 260 EVVQRKKQIAVEAQEILRTDKELIATVRRPAEAEAHRIQQIAEGEKVKQVLLAQAEAEKI 319

Query: 703 RKELLELEALSMAVESTGTAKAE-AESRAEAARIEGEGSVLQAKLKA-QALAIETEAELQ 760
           RK     EA +  +E+ G A+AE  + +AEA +  G+ + +   L+A   +A +  A L 
Sbjct: 320 RK---IGEAEAAVIEAMGKAEAERMKLKAEAYQKYGDAAKMALVLEALPQIAAKIAAPLT 376

Query: 761 RVQKV 765
           +V ++
Sbjct: 377 KVDEI 381



 Score = 33.9 bits (76), Expect = 0.69
 Identities = 36/147 (24%), Positives = 62/147 (42%), Gaps = 10/147 (6%)

Query: 647 DQRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKEL 706
           D +    LQ+S   + E+   + EA   +E Q   ++ + R E  +I      ++   E 
Sbjct: 214 DSKRAFELQKSA-FSEEVNIKTAEAQLAYELQGAREQQKIRQEEIEIEVVQRKKQIAVEA 272

Query: 707 LELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVR 766
            E+      + +T    AEAE+       EGE      K+K   LA   +AE ++++K+ 
Sbjct: 273 QEILRTDKELIATVRRPAEAEAHRIQQIAEGE------KVKQVLLA---QAEAEKIRKIG 323

Query: 767 ELELVYARAQLELEVSKAQQLAEVEVK 793
           E E     A  + E  + +  AE   K
Sbjct: 324 EAEAAVIEAMGKAEAERMKLKAEAYQK 350



 Score = 32.3 bits (72), Expect = 2.0
 Identities = 34/138 (24%), Positives = 55/138 (39%), Gaps = 32/138 (23%)

Query: 668 SQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALS----MAVESTGTAK 723
           S+E   K    +L  E +G  E+QKI         R+E +E+E +     +AVE+    +
Sbjct: 227 SEEVNIKTAEAQLAYELQGAREQQKI---------RQEEIEIEVVQRKKQIAVEAQEILR 277

Query: 724 AEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSK 783
            + E  A   R                     EAE  R+Q++ E E V      + E  K
Sbjct: 278 TDKELIATVRR-------------------PAEAEAHRIQQIAEGEKVKQVLLAQAEAEK 318

Query: 784 AQQLAEVEVKKFKQMTEA 801
            +++ E E    + M +A
Sbjct: 319 IRKIGEAEAAVIEAMGKA 336


>gi|191252785 centrobin, centrosomal BRCA2 interacting protein
           isoform alpha [Homo sapiens]
          Length = 903

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 40/138 (28%), Positives = 72/138 (52%), Gaps = 12/138 (8%)

Query: 665 TTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKA 724
           T   QE   K   Q L++E++ +LER+K   Q EA+ A +   +L     A+  +   + 
Sbjct: 361 TWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQL-----ALVQSEVRRL 415

Query: 725 EAE---SRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEV 781
           E E   +R E   ++ E S++QA+ ++Q + +E+E  +Q  Q+V E     A+AQ E  +
Sbjct: 416 EGELDTARRERDALQLEMSLVQARYESQRIQLESELAVQLEQRVTER---LAQAQ-ESSL 471

Query: 782 SKAQQLAEVEVKKFKQMT 799
            +A  L E   K+ + ++
Sbjct: 472 RQAASLREHHRKQLQDLS 489


>gi|80861396 centrobin, centrosomal BRCA2 interacting protein
           isoform beta [Homo sapiens]
          Length = 925

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 40/138 (28%), Positives = 72/138 (52%), Gaps = 12/138 (8%)

Query: 665 TTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKA 724
           T   QE   K   Q L++E++ +LER+K   Q EA+ A +   +L     A+  +   + 
Sbjct: 361 TWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQL-----ALVQSEVRRL 415

Query: 725 EAE---SRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEV 781
           E E   +R E   ++ E S++QA+ ++Q + +E+E  +Q  Q+V E     A+AQ E  +
Sbjct: 416 EGELDTARRERDALQLEMSLVQARYESQRIQLESELAVQLEQRVTER---LAQAQ-ESSL 471

Query: 782 SKAQQLAEVEVKKFKQMT 799
            +A  L E   K+ + ++
Sbjct: 472 RQAASLREHHRKQLQDLS 489


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 68/284 (23%), Positives = 116/284 (40%), Gaps = 36/284 (12%)

Query: 607  ETSEAKGPDGMALPRPRDQAVFPQNGLVVSSVDVQSVEPVDQRTRDALQRSVQLAIEITT 666
            E  EA   +G A P   D    P+    V      +  P  ++       SV+ A+E   
Sbjct: 1872 EDVEAPEAEGEAQPESEDVET-PEAEWEVQPESEGAEAPEAEKEAQPETESVE-ALETEG 1929

Query: 667  NSQ---EAAAKHEAQRLEQEARGRLERQ-KILDQSEAEK-ARKELLELEALSMAVESTGT 721
              +   E A   EA+   QEA G+ + + ++++  EAE+ A+ E  ++EAL + VE   T
Sbjct: 1930 EDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVE---T 1986

Query: 722  AKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEV 781
             +AE E++ E+  +E               A E E E+Q  ++  + E     AQ + E 
Sbjct: 1987 QEAEGEAQPESEDVE---------------APEAEGEMQEAEEEAQPESDGVEAQPKSEG 2031

Query: 782  SKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLKSTLITDGSTPINL 841
             +AQ     EV+   Q TE  G +      V  PE + +  ++ G     + +     + 
Sbjct: 2032 EEAQ-----EVEGETQKTE--GDAQPESDGVEAPEAEEEAQEAEGE----VQEAEGEAHP 2080

Query: 842  FNTAFGLLGMGPEGQPLGRRVASGPSPGEGISPQSAQAPQAPGD 885
             +          E QP    V +  + GE    +  +AP+  G+
Sbjct: 2081 ESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGE 2124


>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
          Length = 2115

 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 54/211 (25%), Positives = 93/211 (44%), Gaps = 24/211 (11%)

Query: 642 SVEPVDQRTRDALQRSVQLAIEITTNSQEAAAKHEAQR--LEQEARGR------LERQKI 693
           S+E   +R  DAL+   +   E+   ++    +H+ +R  LE+E  GR      L++   
Sbjct: 717 SLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGE 776

Query: 694 LDQSEAEKARKELLELEALSMAVES--TGTAKAEAESRAEAARIEGEGSVLQAKLKAQAL 751
             Q+E E  R+EL E  A     ES      K  A  R      + E +   A  + Q +
Sbjct: 777 AHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLM 836

Query: 752 AIETEAE--LQRVQKVRE--------LELVYARAQ---LELEVSKAQQLAEVEVKKFKQM 798
            ++ E E   Q +Q+ +E         EL  +R Q    EL  + A+ L +V+ K+ +  
Sbjct: 837 TLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQ 896

Query: 799 TEAIGPSTIRDLAVAGPEMQVKLLQSLGLKS 829
             A   ST+++  +A    +V  L++L  K+
Sbjct: 897 KLADDLSTLQE-KMAATSKEVARLETLVRKA 926



 Score = 38.1 bits (87), Expect = 0.037
 Identities = 39/165 (23%), Positives = 73/165 (44%), Gaps = 19/165 (11%)

Query: 648 QRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELL 707
           QR +  L R V+        +++   + +AQ  E E + R E+QK  ++    + + +L 
Sbjct: 642 QREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQ 701

Query: 708 E-LEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIE------------ 754
           E L+AL  +++ T  +  E + RA  A  E +  + + K + ++L  +            
Sbjct: 702 EQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEER 761

Query: 755 -----TEAELQRVQKVRELELVYARAQLELEVSKAQQLAEVEVKK 794
                 EA LQ++ +  + E    R +L  E   AQ  AE E ++
Sbjct: 762 AGRKGLEARLQQLGEAHQAETEVLRREL-AEAMAAQHTAESECEQ 805



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 46/134 (34%), Positives = 62/134 (46%), Gaps = 15/134 (11%)

Query: 672  AAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAE 731
            AA  E+Q  +QE RG+ ER+      E  +A+ +L    AL  A      A+AE E R +
Sbjct: 986  AALMESQGQQQEERGQQEREVARLTQERGRAQADL----ALEKA------ARAELEMRLQ 1035

Query: 732  AARIEG--EGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSKAQQLAE 789
             A  E   E + LQ  L A AL  E E + Q + K+R LE    +   EL     +QL E
Sbjct: 1036 NALNEQRVEFATLQEAL-AHALT-EKEGKDQELAKLRGLEAAQIKELEELR-QTVKQLKE 1092

Query: 790  VEVKKFKQMTEAIG 803
               KK K+     G
Sbjct: 1093 QLAKKEKEHASGSG 1106



 Score = 34.7 bits (78), Expect = 0.41
 Identities = 53/222 (23%), Positives = 96/222 (43%), Gaps = 21/222 (9%)

Query: 668  SQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEA-LSMAVESTGTAKAEA 726
            S++ A   +A +++Q+    ++ Q    Q EA++ + +L EL+A LS   ++    K + 
Sbjct: 1555 SKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQM 1614

Query: 727  E-SRAEAARIEGEGSVLQAKLKA----QALAIETEAELQRV-QKVRELELVYARAQLELE 780
            E ++      + +   LQ +L++    Q    E  AE +R+  ++++  L    A+    
Sbjct: 1615 EKAKTHYDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCR 1674

Query: 781  VSKAQ-QLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLKS-TLITDGSTP 838
               AQ +  E +V    Q    +G   +   A+   E Q K    L + S  L  +  TP
Sbjct: 1675 HLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTP 1734

Query: 839  INLFNTAFGLLGMGPEGQPLGRRVASGPSPGEGISPQSAQAP 880
            +++ +         P  QP G  V     PGE  SP S + P
Sbjct: 1735 LSITSKL-------PRTQPDGTSV-----PGEPASPISQRLP 1764



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 45/188 (23%), Positives = 86/188 (45%), Gaps = 26/188 (13%)

Query: 640 VQSVEPVDQRTRDALQRSVQ--LAIEITTNSQ------EAAA---KHEAQRLEQEARGRL 688
           +Q +    Q   + L+R +   +A + T  S+      E AA   ++E  + E+   G +
Sbjct: 771 LQQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAM 830

Query: 689 ERQKILD-QSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLK 747
            +++++  + E EKAR+EL E +     +ES         S  + +R + E + L A L 
Sbjct: 831 FQEQLMTLKEECEKARQELQEAKEKVAGIES--------HSELQISRQQNELAELHANL- 881

Query: 748 AQALAIETEAELQRVQKVRELELVYAR-AQLELEVSKAQQLAEVEVKKFKQMTEAIGPST 806
           A+AL    E E++  +   +L  +  + A    EV++ + L    V+K  +  E      
Sbjct: 882 ARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETL----VRKAGEQQETASREL 937

Query: 807 IRDLAVAG 814
           +++ A AG
Sbjct: 938 VKEPARAG 945


>gi|157042792 coiled-coil domain containing 64B [Homo sapiens]
          Length = 508

 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 50/189 (26%), Positives = 90/189 (47%), Gaps = 27/189 (14%)

Query: 661 AIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQ------------SEAEKARKEL-L 707
           A+E+  + +   A+   QR EQ+  GR ER + L +            ++A +  +EL  
Sbjct: 118 AVELEGDVEALRAQLGEQRSEQQDSGR-ERARALSELSEQNLRLSQQLAQASQTEQELQR 176

Query: 708 ELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAK---LKAQALAIETEAEL--QRV 762
           EL+AL    ++   A AE  +R E+  ++GE  +LQ++   L+AQ   +  E E    R+
Sbjct: 177 ELDALRGQCQAQALAGAELRTRLES--LQGENQMLQSRRQDLEAQIRGLREEVEKGEGRL 234

Query: 763 QKVRELELVYARAQLE--LEVSKAQQLAEVEVKKFKQMTEAIG----PSTIRDLAVAGPE 816
           Q   E  L+  R + E  LE+ +A+  A   +   +++   +      S ++D  V+   
Sbjct: 235 QTTHEELLLLRRERREHSLELERARSEAGEALSALRRLQRRVSELEEESRLQDADVSAAS 294

Query: 817 MQVKLLQSL 825
           +Q +L  SL
Sbjct: 295 LQSELAHSL 303


>gi|93102364 SWAP-70 protein [Homo sapiens]
          Length = 585

 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 34/132 (25%), Positives = 64/132 (48%), Gaps = 18/132 (13%)

Query: 682 QEARGRLERQKILDQSEAEKARKELL--------ELEALSMAVESTGTAKAEAESRAEAA 733
           ++ R  L ++++ +Q E E+  KEL         ELEA+   +E   +  AE E +    
Sbjct: 320 RQRRKELRKKQLAEQEELERQMKELQAANESKQQELEAVRKKLEEAASRAAEEEKKRLQT 379

Query: 734 RIEGEG---------SVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSKA 784
           ++E +           +++ +++ Q     +E E Q +Q+VRELE +Y + Q  LE  + 
Sbjct: 380 QVELQARFSTELEREKLIRQQMEEQVAQKSSELE-QYLQRVRELEDMYLKLQEALEDERQ 438

Query: 785 QQLAEVEVKKFK 796
            +  E  V+K +
Sbjct: 439 ARQDEETVRKLQ 450



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 63/238 (26%), Positives = 109/238 (45%), Gaps = 30/238 (12%)

Query: 623 RDQAVFPQNGLVVSSVDVQSVEPVDQRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQ 682
           R + +  Q  L     ++Q+     Q+  +A+++ ++   E  + + E   K    ++E 
Sbjct: 327 RKKQLAEQEELERQMKELQAANESKQQELEAVRKKLE---EAASRAAEEEKKRLQTQVEL 383

Query: 683 EAR--GRLERQKILDQSEAEKARKELLELE--------------ALSMAVESTGTAKAEA 726
           +AR    LER+K++ Q   E+  ++  ELE               L  A+E    A+ + 
Sbjct: 384 QARFSTELEREKLIRQQMEEQVAQKSSELEQYLQRVRELEDMYLKLQEALEDERQARQDE 443

Query: 727 ES-RAEAARIEGEGSVLQAKLK----AQALAIE-TEAELQRVQKVRELE---LVYARAQL 777
           E+ R   AR+  E S  +A+L+     Q  AI+ TEAE Q ++  R L+   L  A  QL
Sbjct: 444 ETVRKLQARLLEEESSKRAELEKWHLEQQQAIQTTEAEKQELENQRVLKEQALQEAMEQL 503

Query: 778 E-LEVSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLKSTLITD 834
           E LE+ + Q L + E  K K++  A   +      VA  E  ++L++       LIT+
Sbjct: 504 EQLELERKQALEQYEEVK-KKLEMATNKTKSWKDKVAHHEGLIRLIEPGSKNPHLITN 560


>gi|154354979 myosin X [Homo sapiens]
          Length = 2058

 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 48/158 (30%), Positives = 78/158 (49%), Gaps = 11/158 (6%)

Query: 669 QEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAES 728
           +E   K E +  E+E R R E +    Q E  + ++EL  L+      E T   + + E+
Sbjct: 826 EEEKKKREEEERERE-RERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKEN 884

Query: 729 RA--EAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSKAQQ 786
           +   E  R+E E   LQ   + Q L++ TEA LQ++Q+ R+ EL     +LE E  +A Q
Sbjct: 885 KQVEEILRLEKEIEDLQRMKEQQELSL-TEASLQKLQERRDQEL----RRLEEEACRAAQ 939

Query: 787 LAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQS 824
              +E   F ++ E +  +  R L+V G E   +L +S
Sbjct: 940 -EFLESLNFDEIDECV-RNIERSLSV-GSEFSSELAES 974


>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
          Length = 1460

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 40/160 (25%), Positives = 81/160 (50%), Gaps = 9/160 (5%)

Query: 641 QSVEPVDQRTRDA-LQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEA 699
           +++E  + R R+   QR   L  ++ +++Q   A  +  R EQEA  +  R+++  Q +A
Sbjct: 653 KAIEEEEARMREEESQRLSWLRAQVQSSTQ---ADEDQIRAEQEASLQKLREELESQQKA 709

Query: 700 EKA---RKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETE 756
           E+A   +K    LE L   +E++  ++  A + A+   ++     L+ + K     +E E
Sbjct: 710 ERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKE 769

Query: 757 --AELQRVQKVRELELVYARAQLELEVSKAQQLAEVEVKK 794
             AEL+R+    E +     + L+ ++ +AQQ  E +++K
Sbjct: 770 HSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQK 809



 Score = 37.0 bits (84), Expect = 0.082
 Identities = 35/163 (21%), Positives = 67/163 (41%), Gaps = 1/163 (0%)

Query: 641 QSVEPVDQRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLER-QKILDQSEA 699
           Q +E   +   ++ Q  +Q   E     +E       Q+ EQ      ER QK +++ EA
Sbjct: 601 QVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEA 660

Query: 700 EKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAEL 759
               +E   L  L   V+S+  A  +     + A ++     L+++ KA+  ++E +   
Sbjct: 661 RMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQ 720

Query: 760 QRVQKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAI 802
              Q   E+E      Q  L  +K + L ++  +   +  EA+
Sbjct: 721 MLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAV 763



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 45/188 (23%), Positives = 90/188 (47%), Gaps = 23/188 (12%)

Query: 623 RDQAVFPQNGLVVS-----SVDVQSVEPV---DQRTRDALQRSVQLAIEITTNSQEAAAK 674
           +++A  P+  + VS     S +V+S EPV   +Q +  AL+   +   ++    Q    +
Sbjct: 553 QEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLE 612

Query: 675 HEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAAR 734
            + ++++Q       R+K+  + E     +E+L L        S+   + +     E AR
Sbjct: 613 SKQEKMQQL------REKLCQEEE-----EEILRLHQQKEQSLSSLRERLQKAIEEEEAR 661

Query: 735 IEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSKAQQLAEVEVKK 794
           +  E S   + L+AQ  +  T+A+  +++  +E  L   R +LE +  KA++ A +E +K
Sbjct: 662 MREEESQRLSWLRAQVQS-STQADEDQIRAEQEASLQKLREELESQ-QKAER-ASLE-QK 717

Query: 795 FKQMTEAI 802
            +QM E +
Sbjct: 718 NRQMLEQL 725



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 34/144 (23%), Positives = 65/144 (45%), Gaps = 7/144 (4%)

Query: 643 VEPVDQRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLE--RQKILDQSEAE 700
           V+   Q   D ++   + +++      E+  K E   LEQ+ R  LE  +++I    ++E
Sbjct: 677 VQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSE 736

Query: 701 KARKELLELEALSMAVESTGTAKAEAESRAE---AARIEGEGSVLQAKLKAQALAIETEA 757
           +A     + +AL    E     + EA +  E   +A +E   S L+AK +    +++ + 
Sbjct: 737 QAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKK- 795

Query: 758 ELQRVQKVRELELVYARAQLELEV 781
            +Q  Q+  E +L     Q+E  V
Sbjct: 796 -IQEAQQKEEAQLQKCLGQVEHRV 818



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 41/190 (21%), Positives = 74/190 (38%), Gaps = 16/190 (8%)

Query: 641  QSVEPVDQRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAE 700
            Q VE   +R  D ++   Q  +       EA  + +   L     G LER +   + E E
Sbjct: 841  QEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELE 900

Query: 701  KARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQ 760
              R+E          +E       E E + +   ++ E      K +   L ++ E   +
Sbjct: 901  TVRQE------QHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARR 954

Query: 761  RVQKVRELELVYARAQLELEVSKAQQLAEVE------VKKFKQMTEAIGPSTIRDLAVAG 814
              Q++ +++   A  + E   +  QQL E +      ++  +Q+ E +     R L +  
Sbjct: 955  EKQQLLDVQRQVA-LKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKL-- 1011

Query: 815  PEMQVKLLQS 824
             E QV LLQ+
Sbjct: 1012 -ESQVDLLQA 1020


>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
          Length = 2017

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 40/137 (29%), Positives = 68/137 (49%), Gaps = 10/137 (7%)

Query: 670  EAAAKHEAQRLEQEARGRLER----QKILDQSEAEK--ARKELLELEALSMAVEST--GT 721
            EAAA +  Q+L+ E R   ER    Q+ L Q EAEK    +  L LE   +A+  T    
Sbjct: 1826 EAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKV 1885

Query: 722  AKAEAESRAEAARIEGEGSVLQAKLKAQALAI-ETEAELQRVQ-KVRELELVYARAQLEL 779
             + +  S  +  R+  E   L   L    L + E + ++Q+++ +V  LE  ++ AQLE+
Sbjct: 1886 EREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEV 1945

Query: 780  EVSKAQQLAEVEVKKFK 796
            +  + Q   + EV++ +
Sbjct: 1946 DAQQQQLELQQEVERLR 1962



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 68/258 (26%), Positives = 103/258 (39%), Gaps = 56/258 (21%)

Query: 619  LPRPRDQAVFPQNGLVVSSVDVQSVEPVDQRTRDALQRSVQLAIEITTNSQEAAAKHEAQ 678
            LP  R +    Q  L   S  +   E   ++ R   QR V+ A+E     +EA AK  A 
Sbjct: 822  LPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVE-ALERAAREKEALAKEHAG 880

Query: 679  RLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGE 738
               Q      E + +     +E+A +  LE EAL  ++       A+ E+R E    EG+
Sbjct: 881  LAVQLVAAEREGRTL-----SEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQ 935

Query: 739  GSVL-----------------------------------QAKLKAQALAIET----EAEL 759
              +L                                   QA+ +AQA   E     E +L
Sbjct: 936  ALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDL 995

Query: 760  QRVQKVREL---ELVYARAQLELEVSKAQQ--LAEVEVKKFKQMTEAIGPSTIRD--LAV 812
            QR+Q+ +E    EL   RAQL+ ++ + Q+  LA +E +K +   E       RD  L +
Sbjct: 996  QRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLL 1055

Query: 813  AGPEMQVKLLQSLGLKST 830
            A  E Q    Q+L LK +
Sbjct: 1056 AESEKQ----QALSLKES 1069



 Score = 35.0 bits (79), Expect = 0.31
 Identities = 51/164 (31%), Positives = 80/164 (48%), Gaps = 35/164 (21%)

Query: 653 ALQRSVQLAIEITTNSQEAAAKHEA-----QRLEQE----------ARGRLERQ-KILDQ 696
           +LQ + Q A E+    ++  A  E       RLE+E           R  LER  + L+Q
Sbjct: 611 SLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQ 670

Query: 697 SEAEKA--RKELLEL-EALSMA------VESTGTAKAEAESRAEAARIEGEGSVLQAKLK 747
            E +++   KEL+E+ EALS A      +++     AEA ++AEA R+E E S+   KL+
Sbjct: 671 LEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSM--TKLR 728

Query: 748 AQALAIETEAELQRVQKVRE------LELVYARAQLELEVSKAQ 785
           A+  +++    L ++  + E      L+L    AQLE E S  Q
Sbjct: 729 AEEASLQD--SLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQ 770



 Score = 34.3 bits (77), Expect = 0.53
 Identities = 58/250 (23%), Positives = 102/250 (40%), Gaps = 36/250 (14%)

Query: 615  DGMALPRPRDQAVFPQNGLVVSSVDVQSVEPVDQRTRDALQRSVQLAIEITTNSQEAAAK 674
            +G AL   ++       GL    +  Q    +D+      Q+ VQ   E   + +E  A 
Sbjct: 933  EGQALLLAKETLTGELAGLRQQIIATQEKASLDKELM--AQKLVQAEREAQASLREQRAA 990

Query: 675  HEA--QRLEQEARG---RLERQKILDQSEAEKARKELL-----ELEALSMAVEST----- 719
            HE   QRL++E       LE ++   QS+ ++ ++ELL     E E LS  + +      
Sbjct: 991  HEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERD 1050

Query: 720  -GTAKAEAESRAEAARIEGEGSVLQAKL-----KAQALAIETEAELQRVQKVRELE---- 769
             G   AE+E +   +  E E + L  KL         +++E E + +  Q  +E +    
Sbjct: 1051 EGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTV 1110

Query: 770  --LVYARAQLELEVSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPE---MQVKLLQS 824
              L      L  +  +A      EV++ ++    +G    RD  +   E    Q++LL+ 
Sbjct: 1111 NALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQ--RDSCLREAEELRTQLRLLED 1168

Query: 825  L--GLKSTLI 832
               GL+  L+
Sbjct: 1169 ARDGLRRELL 1178



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 32/140 (22%), Positives = 67/140 (47%), Gaps = 10/140 (7%)

Query: 648  QRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELL 707
            ++ R AL+R++         S E   +  A++      GRL+R     + E  +A++++ 
Sbjct: 1872 EKDRVALRRTLDKVEREKLRSHEDTVRLSAEK------GRLDRTLTGAELELAEAQRQIQ 1925

Query: 708  ELEALSMAVE-STGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVR 766
            +LEA  + +E S   A+ E +++ +   ++ E   L++        +E      R Q+VR
Sbjct: 1926 QLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERLRSAQAQTERTLEARERAHR-QRVR 1984

Query: 767  ELE--LVYARAQLELEVSKA 784
             LE  +   + QL+ E+ ++
Sbjct: 1985 GLEEQVSTLKGQLQQELRRS 2004



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 44/145 (30%), Positives = 73/145 (50%), Gaps = 12/145 (8%)

Query: 655 QRSVQL---AIEITTNSQEAAAKHEAQRLEQEARG-RLERQKILDQSEAEKARKELLELE 710
           QR VQ    A E+ +  +   A H  Q  +Q+A   R ER+K+    E  + +++ LE E
Sbjct: 588 QREVQRLRSANELLSREKSNLA-HSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLE-E 645

Query: 711 ALSMAVESTGTAKAEAE-SRAEAARIEGEGSVLQAKL--KAQALAIET-EAELQRVQKVR 766
               AV+     + E E S  +  ++EG+ SVL  +L    +AL+  T + ++ + +K  
Sbjct: 646 EQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAE 705

Query: 767 ELE-LVYARA-QLELEVSKAQQLAE 789
             E L  A A ++ELE+S  +  AE
Sbjct: 706 VAEALTKAEAGRVELELSMTKLRAE 730



 Score = 31.2 bits (69), Expect = 4.5
 Identities = 56/231 (24%), Positives = 85/231 (36%), Gaps = 37/231 (16%)

Query: 651 RDALQRSVQLAIEITTNSQEAAAKHEAQRL-EQEARGRLERQKILDQSEAEKARKELLEL 709
           RD LQ   +LA       +         RL E  A   LE+Q +L     E+ R ++L  
Sbjct: 319 RDLLQLGGELARTSRAVQEAGLGLSTGLRLAESRAEAALEKQALLQAQLEEQLRDKVLRE 378

Query: 710 EALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELE 769
           + L+     +   KA+  +R        E  +   +L+ Q L  + +      +K+  LE
Sbjct: 379 KDLAQQQMQSDLDKADLSARVT------ELGLAVKRLEKQNLE-KDQVNKDLTEKLEALE 431

Query: 770 LVYARAQLELEVSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLKS 829
            +  + Q  LE    + L +                T+RDLA A        +Q  G + 
Sbjct: 432 SLRLQEQAALETEDGEGLQQ----------------TLRDLAQAVLSDSESGVQLSGSER 475

Query: 830 TLITDGSTPINLFNTAFGLLGMGPEGQPLGRRVASGPSPGEGISPQSAQAP 880
           T   D S       +  GL G      P  RR     SPG G SP+   +P
Sbjct: 476 T--ADASN-----GSLRGLSGQRTPSPP--RR----SSPGRGRSPRRGPSP 513



 Score = 30.8 bits (68), Expect = 5.9
 Identities = 38/157 (24%), Positives = 70/157 (44%), Gaps = 15/157 (9%)

Query: 650 TRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQE--------ARGRLERQKILDQSEAEK 701
           TR+  Q    + +  T  +   + + E Q L+QE        A+ R ER ++  +  A  
Sbjct: 56  TRNLSQPESPVLLPATEMASLLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVS 115

Query: 702 ARKE-LLELEALSMAV-ESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAEL 759
            R E  L LE   +   E  G  +   E R +   ++ E +  + KL+A     + +A+L
Sbjct: 116 ERLEQALRLEPGELETQEPRGLVRQSVELRRQ---LQEEQASYRRKLQAYQEGQQRQAQL 172

Query: 760 QRVQKVRELELVYARAQLELEVSKAQQLAEVEVKKFK 796
             VQ+++   L Y +   ELE    ++  E+E ++ +
Sbjct: 173 --VQRLQGKILQYKKRCSELEQQLLERSGELEQQRLR 207


>gi|4504063 golgin 97 [Homo sapiens]
          Length = 767

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 50/183 (27%), Positives = 88/183 (48%), Gaps = 19/183 (10%)

Query: 648 QRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQE------ARGRLERQKILDQSEAEK 701
           +RT+ AL+  + +A+E T  + +  A+   ++LEQE       R   ER     Q E +K
Sbjct: 410 ERTQ-ALEAQI-VALERTRAADQTTAEQGMRQLEQENAALKECRNEYERSLQNHQFELKK 467

Query: 702 ARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKL--KAQALAIETEAEL 759
            ++E  + E +S+A+     A+A  E R +    + + + L A +  K Q L  +TE  L
Sbjct: 468 LKEEWSQREIVSVAM-----AQALEEVRKQREEFQQQAANLTAIIDEKEQNLREKTEVLL 522

Query: 760 QRVQKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQV 819
           Q+ Q++ +LE  +  A L++     Q  AE+E  +  +  EA   +   DL      +Q 
Sbjct: 523 QKEQEILQLERGHNSALLQIH----QLQAELEALRTLKAEEAAVVAEQEDLLRLRGPLQA 578

Query: 820 KLL 822
           + L
Sbjct: 579 EAL 581


>gi|31982906 cingulin-like 1 [Homo sapiens]
          Length = 1302

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 58/208 (27%), Positives = 89/208 (42%), Gaps = 43/208 (20%)

Query: 654 LQRSVQLAIEITTNSQEAAAKHEA--QRLEQEARGRLER----QKILDQSEAEKARKELL 707
           LQR +QL ++   N +E   +  A  + L  +   ++E     Q+ L++SE E  RK L 
Sbjct: 626 LQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGE-LRKNLE 684

Query: 708 ELEALSMAVESTGT-----------------AKAEAESRAEAARIEGEGSVLQAKLKAQA 750
           EL  + M  E   T                 +   +E R + A IE    +LQAK   Q 
Sbjct: 685 ELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIE---ELLQAKQDLQD 741

Query: 751 LAIETEAELQRVQKVRELELVYARAQLELEVS-------KAQQLAEVEVKKFKQMTEAI- 802
           L I  E +   ++K RE EL   +  L+ EVS       K ++  + E++  ++  E   
Sbjct: 742 LLIAKEEQEDLLRK-RERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEAT 800

Query: 803 -------GPSTIRDLAVAGPEMQVKLLQ 823
                    S   +   AG EM+VKLLQ
Sbjct: 801 KNVEVLASRSNTSEQDQAGTEMRVKLLQ 828


>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
          Length = 749

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 42/145 (28%), Positives = 65/145 (44%), Gaps = 6/145 (4%)

Query: 665 TTNSQEAAAK-HEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAK 723
           TT+ +EA     E +RL +E R + ER++  +Q E E+ ++E    E      E   T +
Sbjct: 473 TTDPEEATRLLAEKRRLAREQREKEERER-REQEELERQKRE----ELAQRVAEERTTRR 527

Query: 724 AEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSK 783
            E   R EA +   +   LQ + + +AL    EAE  + QK  E  +     ++  E  K
Sbjct: 528 EEESRRLEAEQAREKEEQLQRQAEERALREREEAERAQRQKEEEARVREEAERVRQEREK 587

Query: 784 AQQLAEVEVKKFKQMTEAIGPSTIR 808
             Q  E E  + K+  E I   T R
Sbjct: 588 HFQREEQERLERKKRLEEIMKRTRR 612



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 23/96 (23%), Positives = 50/96 (52%), Gaps = 5/96 (5%)

Query: 644 EPVDQRTRDALQRSVQLAIEITTNSQEAAAKHEAQRL---EQEARGRLERQKILDQSEAE 700
           E ++++ R+ L + V  A E TT  +E + + EA++    E++ + + E + + ++ EAE
Sbjct: 505 EELERQKREELAQRV--AEERTTRREEESRRLEAEQAREKEEQLQRQAEERALREREEAE 562

Query: 701 KARKELLELEALSMAVESTGTAKAEAESRAEAARIE 736
           +A+++  E   +    E     + +   R E  R+E
Sbjct: 563 RAQRQKEEEARVREEAERVRQEREKHFQREEQERLE 598


>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
          Length = 2325

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 36/130 (27%), Positives = 63/130 (48%), Gaps = 23/130 (17%)

Query: 665 TTNSQEAAAKHEAQRLEQEARGRLERQKILDQS---------EAEKARKELLELEALSMA 715
           T   Q   A++E ++L  E    L+R   ++Q          +AE  RKEL ELE+    
Sbjct: 627 TIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELES---- 682

Query: 716 VESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQ-----ALAIETEAELQRVQKVRELEL 770
                  + + E  A   + +G+ S  +A+L+A+     A A + + EL++V ++ +LE 
Sbjct: 683 -----ALQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKVTRLTQLEQ 737

Query: 771 VYARAQLELE 780
              +A+LE E
Sbjct: 738 SALQAELEKE 747


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 47/170 (27%), Positives = 81/170 (47%), Gaps = 17/170 (10%)

Query: 674  KHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAA 733
            KHEA   + E R R E ++   + E EK R++L          +ST  +   AE +A+ A
Sbjct: 1024 KHEAMITDLEERLRREEKQ---RQELEKTRRKL--------EGDSTDLSDQIAELQAQIA 1072

Query: 734  RIEGEGSVLQAKLKAQALAIETEAELQRV--QKVRELELVYARAQLELEVSKA-QQLAEV 790
             ++ + +  + +L+A    +E EA  + +  +K+RELE   +  Q +LE  +A +  AE 
Sbjct: 1073 ELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEK 1132

Query: 791  EVKKFKQMTEAIGP--STIRDLAVAGPEMQVKLLQSLG-LKSTLITDGST 837
            + +   +  EA+        D   A  E++ K  Q +  LK TL  +  T
Sbjct: 1133 QKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKT 1182



 Score = 31.2 bits (69), Expect = 4.5
 Identities = 38/170 (22%), Positives = 75/170 (44%), Gaps = 24/170 (14%)

Query: 650  TRDALQRSVQLAIE-ITTNSQEAAAKHEA-----QRLEQEARGRL-----ERQKILDQSE 698
            T + ++R +Q  +E ++   +E  A ++       RL+QE    L     +RQ   +  +
Sbjct: 1382 TAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEK 1441

Query: 699  AEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAE 758
             +K   +LL  E    A  +    +AEAE+R +  +       L+        A+E +AE
Sbjct: 1442 KQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEE-------AMEQKAE 1494

Query: 759  LQRVQKVRELELVYARAQLE------LEVSKAQQLAEVEVKKFKQMTEAI 802
            L+R+ K    E+    +  +       E+ K+++  E +V++ K   E +
Sbjct: 1495 LERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEEL 1544


>gi|35038601 spindle assembly abnormal protein 6 [Homo sapiens]
          Length = 657

 Score = 42.0 bits (97), Expect = 0.003
 Identities = 41/153 (26%), Positives = 72/153 (47%), Gaps = 16/153 (10%)

Query: 659 QLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVES 718
           QL  ++    QE   K +     +EA   ++ QK++ +   EK + +L +LEA    ++S
Sbjct: 319 QLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEA---TIKS 375

Query: 719 TGTAKAEAESRAEAARIEGEGSVLQAKLK--------AQALAIETEAELQRVQKVRELEL 770
                 +A    +  +++G+   L  KLK         + L  E E +LQ+ QK  EL+ 
Sbjct: 376 LSAELLKANEIIK--KLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQK--ELQD 431

Query: 771 VYARAQL-ELEVSKAQQLAEVEVKKFKQMTEAI 802
           V    ++ E EV K Q+  E  VKK ++  + +
Sbjct: 432 VGQSLRIKEQEVCKLQEQLEATVKKLEESKQLL 464


>gi|88196790 coiled-coil domain containing 88 [Homo sapiens]
          Length = 1476

 Score = 42.0 bits (97), Expect = 0.003
 Identities = 50/185 (27%), Positives = 86/185 (46%), Gaps = 20/185 (10%)

Query: 649 RTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQ--KILDQSEAEKARKEL 706
           R R+A++ + Q   E+ + SQE  A  EA       R + ER+  ++  QSEA + R ++
Sbjct: 792 RLREAVEAAGQ---ELESASQEREALVEALAAAGRERRQWEREGSRLRAQSEAAEERMQV 848

Query: 707 LELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVR 766
           LE E      E+    + +   +AE  +    G  L A+L+     +E +A L+R + +R
Sbjct: 849 LESEGRQHLEEAERERREKEALQAELEKAVVRGKELGARLEHLQRELE-QAALERQEFLR 907

Query: 767 ELELVYARAQ-----LELEV-----SKAQQLAEVEVKKFKQMTEAI----GPSTIRDLAV 812
           E E  + R Q     LE E+     SK + L E++ +  +   E      GP+ +     
Sbjct: 908 EKESQHQRYQGLEQRLEAELQAAATSKEEALMELKTRALQLEEELFQLRQGPAGLGPKKR 967

Query: 813 AGPEM 817
           A P++
Sbjct: 968 AEPQL 972



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 41/166 (24%), Positives = 72/166 (43%), Gaps = 19/166 (11%)

Query: 673 AKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAEA 732
           A+ EA R E+ A+ R + + + D+ EA+  + E    EA  ++ E     +AEAE+  EA
Sbjct: 725 AEQEALR-EEVAQLRRKAEALGDELEAQARKLEAQNTEAARLSKELAQARRAEAEAHREA 783

Query: 733 -----------ARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEV 781
                        +E  G  L++  + +   +E  A   R ++  E E    RAQ E   
Sbjct: 784 EAQAWEQARLREAVEAAGQELESASQEREALVEALAAAGRERRQWEREGSRLRAQSEAAE 843

Query: 782 SKAQQLAE------VEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKL 821
            + Q L         E ++ ++  EA+  + +    V G E+  +L
Sbjct: 844 ERMQVLESEGRQHLEEAERERREKEAL-QAELEKAVVRGKELGARL 888


>gi|5031699 flotillin 1 [Homo sapiens]
          Length = 427

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 53/232 (22%), Positives = 95/232 (40%), Gaps = 34/232 (14%)

Query: 582 AVASVTFDDFHKN-----------SARIIRTAVFGFETSEAKGPDGMALPRPRDQAVFPQ 630
           +V S T  D H +           +A++ + A  G   +EAK   G+   + + + V  Q
Sbjct: 145 SVVSYTLKDIHDDQDYLHSLGKARTAQVQKDARIG--EAEAKRDAGIREAKAKQEKVSAQ 202

Query: 631 NGLVVSSVDVQ----------SVEPVDQRTRDALQRSVQLAI---EITTNSQEAAAKHEA 677
               +     Q           +E   +R +  L   +Q+A    +I     +      A
Sbjct: 203 YLSEIEMAKAQRDYELKKAAYDIEVNTRRAQADLAYQLQVAKTKQQIEEQRVQVQVVERA 262

Query: 678 QRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEG 737
           Q++  + +    R+K L+    + A  E  +LE L+ A +S    +AEAE+ +   R E 
Sbjct: 263 QQVAVQEQEIARREKELEARVRKPAEAERYKLERLAEAEKSQLIMQAEAEAASVRMRGEA 322

Query: 738 EGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSKAQQLAE 789
           E   + A+ +A+A         Q  +K    +L    AQL++ + K  Q+AE
Sbjct: 323 EAFAIGARARAEA--------EQMAKKAEAFQLYQEAAQLDMLLEKLPQVAE 366



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 40/183 (21%), Positives = 79/183 (43%), Gaps = 25/183 (13%)

Query: 632 GLVVSSVDVQSVEPVDQRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQ 691
           G+ V S  ++ +   DQ    +L ++    ++      EA AK +A   E +A+      
Sbjct: 143 GISVVSYTLKDIHD-DQDYLHSLGKARTAQVQKDARIGEAEAKRDAGIREAKAKQEKVSA 201

Query: 692 KILDQSEAEKARKELLELEALSMAVE-STGTAKAEAESRAEAAR----IEGEGSVLQAKL 746
           + L + E  KA+++  EL+  +  +E +T  A+A+   + + A+    IE +   +Q   
Sbjct: 202 QYLSEIEMAKAQRDY-ELKKAAYDIEVNTRRAQADLAYQLQVAKTKQQIEEQRVQVQVVE 260

Query: 747 KAQALAIE------------------TEAELQRVQKVRELELVYARAQLELEVSKAQQLA 788
           +AQ +A++                   EAE  +++++ E E      Q E E +  +   
Sbjct: 261 RAQQVAVQEQEIARREKELEARVRKPAEAERYKLERLAEAEKSQLIMQAEAEAASVRMRG 320

Query: 789 EVE 791
           E E
Sbjct: 321 EAE 323


>gi|4505257 moesin [Homo sapiens]
          Length = 577

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 38/139 (27%), Positives = 68/139 (48%), Gaps = 8/139 (5%)

Query: 648 QRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARG-RLERQKILDQSEAEKARKEL 706
           ++ ++ ++R  +  +E     +E   K + +  EQ  R   LE+++   QSEAEK  KE 
Sbjct: 334 EKEKEKIEREKEELMERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKER 393

Query: 707 LELEALSMAV--ESTGTAKAEAESRAEAARIEGEGSVLQ-AKLKAQALAIETEAELQRVQ 763
            E E    A+   S    K + +   E A +    S L+ A+ K ++ A+E + + Q VQ
Sbjct: 394 QEAEEAKEALLQASRDQKKTQEQLALEMAELTARISQLEMARQKKESEAVEWQQKAQMVQ 453

Query: 764 KVRELELVYARAQLELEVS 782
           +    +L   RA+L+  +S
Sbjct: 454 E----DLEKTRAELKTAMS 468



 Score = 38.9 bits (89), Expect = 0.022
 Identities = 43/161 (26%), Positives = 87/161 (54%), Gaps = 15/161 (9%)

Query: 637 SVDVQSVEPVDQRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQ 696
           +++VQ ++   Q   +  Q+ ++ A+      +   A+ E +++E+E    +ER K +++
Sbjct: 299 TIEVQQMKA--QAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEELMERLKQIEE 356

Query: 697 SEAEKARKELLELEALSMAVE-STGTAKAEAESRAEAAR--IEGEGSVLQA----KLKAQ 749
            + +KA++EL E    ++ +E     A++EAE  A+  +   E + ++LQA    K   +
Sbjct: 357 -QTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQE 415

Query: 750 ALAIETEAELQRVQKVRELELVYARAQLELEVSKAQQLAEV 790
            LA+E  AEL    ++ +LE+  AR + E E  + QQ A++
Sbjct: 416 QLALEM-AEL--TARISQLEM--ARQKKESEAVEWQQKAQM 451


>gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo
           sapiens]
          Length = 551

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 42/177 (23%), Positives = 77/177 (43%), Gaps = 25/177 (14%)

Query: 646 VDQRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARK- 704
           +DQ      Q+S+Q   E+    +E   +   Q +EQ  + + ER  + +Q E EK +  
Sbjct: 228 LDQMMEVERQKSIQRQEELERKRREERIRGRRQIVEQMEKNQEERSLLAEQREQEKEQML 287

Query: 705 ELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQ--------------- 749
           E +E        +     + + + +AE  RI  E    +A+L AQ               
Sbjct: 288 EYMEQLQEEDLKDMERRQQQKLKMQAEIKRINDENQKQKAELLAQEKLADQMVMEFTKKK 347

Query: 750 -ALAIETEAELQRVQKVRELELVYARA--------QLELEVSKAQQLAEVEVKKFKQ 797
            A   E EAE +R+++ +E E+   RA        Q E +  +A++  EV  +++++
Sbjct: 348 MAREAEFEAEQERIRREKEKEIARLRAMQEKAQDYQAEQDALRAKRNQEVADREWRR 404



 Score = 30.8 bits (68), Expect = 5.9
 Identities = 38/143 (26%), Positives = 64/143 (44%), Gaps = 18/143 (12%)

Query: 669 QEAAAKHEAQRLEQEAR--GRLERQKILDQSEAE-KARKELLELEALSMAVESTGTAKAE 725
           +E  A+ +A + E+EA     + R+KI+ Q E      K+L +LE +         AK  
Sbjct: 122 EELEARDQAFKKEKEATMDAVMTRKKIMKQKEMVWNNNKKLSDLEEV---------AKER 172

Query: 726 AES---RAEAARIEGEGSVLQAK---LKAQALAIETEAELQRVQKVRELELVYARAQLEL 779
           A++   RA   R+E E  +       L A+  AI     L++ Q  +EL+    R    +
Sbjct: 173 AQNLLQRANKLRMEQEEELKDMSKIILNAKCHAIRDAQILEKQQIQKELDTEEKRLDQMM 232

Query: 780 EVSKAQQLAEVEVKKFKQMTEAI 802
           EV + + +   E  + K+  E I
Sbjct: 233 EVERQKSIQRQEELERKRREERI 255


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.134    0.382 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,893,811
Number of Sequences: 37866
Number of extensions: 1587883
Number of successful extensions: 6724
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 289
Number of HSP's that attempted gapping in prelim test: 5863
Number of HSP's gapped (non-prelim): 945
length of query: 893
length of database: 18,247,518
effective HSP length: 111
effective length of query: 782
effective length of database: 14,044,392
effective search space: 10982714544
effective search space used: 10982714544
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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