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Search of human proteins with 19913410
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19913410 major vault protein [Homo sapiens]
(893 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19913410 major vault protein [Homo sapiens] 1753 0.0
gi|19913412 major vault protein [Homo sapiens] 1753 0.0
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 47 1e-04
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 47 1e-04
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 47 1e-04
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 47 1e-04
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 47 1e-04
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 47 1e-04
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 47 1e-04
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 47 1e-04
gi|94538362 flotillin 2 [Homo sapiens] 46 2e-04
gi|191252785 centrobin, centrosomal BRCA2 interacting protein is... 46 2e-04
gi|80861396 centrobin, centrosomal BRCA2 interacting protein iso... 46 2e-04
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 45 3e-04
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 44 7e-04
gi|157042792 coiled-coil domain containing 64B [Homo sapiens] 44 7e-04
gi|93102364 SWAP-70 protein [Homo sapiens] 44 9e-04
gi|154354979 myosin X [Homo sapiens] 44 9e-04
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 43 0.001
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 43 0.001
gi|4504063 golgin 97 [Homo sapiens] 43 0.001
gi|31982906 cingulin-like 1 [Homo sapiens] 43 0.001
gi|4505101 microtubule-associated protein 7 [Homo sapiens] 43 0.001
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 43 0.001
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 42 0.002
gi|35038601 spindle assembly abnormal protein 6 [Homo sapiens] 42 0.003
gi|88196790 coiled-coil domain containing 88 [Homo sapiens] 42 0.003
gi|5031699 flotillin 1 [Homo sapiens] 42 0.003
gi|4505257 moesin [Homo sapiens] 42 0.003
gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo s... 42 0.003
>gi|19913410 major vault protein [Homo sapiens]
Length = 893
Score = 1753 bits (4541), Expect = 0.0
Identities = 893/893 (100%), Positives = 893/893 (100%)
Query: 1 MATEEFIIRIPPYHYIHVLDQNSNVSRVEVGPKTYIRQDNERVLFAPMRMVTVPPRHYCT 60
MATEEFIIRIPPYHYIHVLDQNSNVSRVEVGPKTYIRQDNERVLFAPMRMVTVPPRHYCT
Sbjct: 1 MATEEFIIRIPPYHYIHVLDQNSNVSRVEVGPKTYIRQDNERVLFAPMRMVTVPPRHYCT 60
Query: 61 VANPVSRDAQGLVLFDVTGQVRLRHADLEIRLAQDPFPLYPGEVLEKDITPLQVVLPNTA 120
VANPVSRDAQGLVLFDVTGQVRLRHADLEIRLAQDPFPLYPGEVLEKDITPLQVVLPNTA
Sbjct: 61 VANPVSRDAQGLVLFDVTGQVRLRHADLEIRLAQDPFPLYPGEVLEKDITPLQVVLPNTA 120
Query: 121 LHLKALLDFEDKDGDKVVAGDEWLFEGPGTYIPRKEVEVVEIIQATIIRQNQALRLRARK 180
LHLKALLDFEDKDGDKVVAGDEWLFEGPGTYIPRKEVEVVEIIQATIIRQNQALRLRARK
Sbjct: 121 LHLKALLDFEDKDGDKVVAGDEWLFEGPGTYIPRKEVEVVEIIQATIIRQNQALRLRARK 180
Query: 181 ECWDRDGKERVTGEEWLVTTVGAYLPAVFEEVLDLVDAVILTEKTALHLRARRNFRDFRG 240
ECWDRDGKERVTGEEWLVTTVGAYLPAVFEEVLDLVDAVILTEKTALHLRARRNFRDFRG
Sbjct: 181 ECWDRDGKERVTGEEWLVTTVGAYLPAVFEEVLDLVDAVILTEKTALHLRARRNFRDFRG 240
Query: 241 VSRRTGEEWLVTVQDTEAHVPDVHEEVLGVVPITTLGPHNYCVILDPVGPDGKNQLGQKR 300
VSRRTGEEWLVTVQDTEAHVPDVHEEVLGVVPITTLGPHNYCVILDPVGPDGKNQLGQKR
Sbjct: 241 VSRRTGEEWLVTVQDTEAHVPDVHEEVLGVVPITTLGPHNYCVILDPVGPDGKNQLGQKR 300
Query: 301 VVKGEKSFFLQPGEQLEQGIQDVYVLSEQQGLLLRALQPLEEGEDEEKVSHQAGDHWLIR 360
VVKGEKSFFLQPGEQLEQGIQDVYVLSEQQGLLLRALQPLEEGEDEEKVSHQAGDHWLIR
Sbjct: 301 VVKGEKSFFLQPGEQLEQGIQDVYVLSEQQGLLLRALQPLEEGEDEEKVSHQAGDHWLIR 360
Query: 361 GPLEYVPSAKVEVVEERQAIPLDENEGIYVQDVKTGKVRAVIGSTYMLTQDEVLWEKELP 420
GPLEYVPSAKVEVVEERQAIPLDENEGIYVQDVKTGKVRAVIGSTYMLTQDEVLWEKELP
Sbjct: 361 GPLEYVPSAKVEVVEERQAIPLDENEGIYVQDVKTGKVRAVIGSTYMLTQDEVLWEKELP 420
Query: 421 PGVEELLNKGQDPLADRGEKDTAKSLQPLAPRNKTRVVSYRVPHNAAVQVYDYREKRARV 480
PGVEELLNKGQDPLADRGEKDTAKSLQPLAPRNKTRVVSYRVPHNAAVQVYDYREKRARV
Sbjct: 421 PGVEELLNKGQDPLADRGEKDTAKSLQPLAPRNKTRVVSYRVPHNAAVQVYDYREKRARV 480
Query: 481 VFGPELVSLGPEEQFTVLSLSAGRPKRPHARRALCLLLGPDFFTDVITIETADHARLQLQ 540
VFGPELVSLGPEEQFTVLSLSAGRPKRPHARRALCLLLGPDFFTDVITIETADHARLQLQ
Sbjct: 481 VFGPELVSLGPEEQFTVLSLSAGRPKRPHARRALCLLLGPDFFTDVITIETADHARLQLQ 540
Query: 541 LAYNWHFEVNDRKDPQETAKLFSVPDFVGDACKAIASRVRGAVASVTFDDFHKNSARIIR 600
LAYNWHFEVNDRKDPQETAKLFSVPDFVGDACKAIASRVRGAVASVTFDDFHKNSARIIR
Sbjct: 541 LAYNWHFEVNDRKDPQETAKLFSVPDFVGDACKAIASRVRGAVASVTFDDFHKNSARIIR 600
Query: 601 TAVFGFETSEAKGPDGMALPRPRDQAVFPQNGLVVSSVDVQSVEPVDQRTRDALQRSVQL 660
TAVFGFETSEAKGPDGMALPRPRDQAVFPQNGLVVSSVDVQSVEPVDQRTRDALQRSVQL
Sbjct: 601 TAVFGFETSEAKGPDGMALPRPRDQAVFPQNGLVVSSVDVQSVEPVDQRTRDALQRSVQL 660
Query: 661 AIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTG 720
AIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTG
Sbjct: 661 AIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTG 720
Query: 721 TAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELE 780
TAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELE
Sbjct: 721 TAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELE 780
Query: 781 VSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLKSTLITDGSTPIN 840
VSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLKSTLITDGSTPIN
Sbjct: 781 VSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLKSTLITDGSTPIN 840
Query: 841 LFNTAFGLLGMGPEGQPLGRRVASGPSPGEGISPQSAQAPQAPGDNHVVPVLR 893
LFNTAFGLLGMGPEGQPLGRRVASGPSPGEGISPQSAQAPQAPGDNHVVPVLR
Sbjct: 841 LFNTAFGLLGMGPEGQPLGRRVASGPSPGEGISPQSAQAPQAPGDNHVVPVLR 893
>gi|19913412 major vault protein [Homo sapiens]
Length = 893
Score = 1753 bits (4541), Expect = 0.0
Identities = 893/893 (100%), Positives = 893/893 (100%)
Query: 1 MATEEFIIRIPPYHYIHVLDQNSNVSRVEVGPKTYIRQDNERVLFAPMRMVTVPPRHYCT 60
MATEEFIIRIPPYHYIHVLDQNSNVSRVEVGPKTYIRQDNERVLFAPMRMVTVPPRHYCT
Sbjct: 1 MATEEFIIRIPPYHYIHVLDQNSNVSRVEVGPKTYIRQDNERVLFAPMRMVTVPPRHYCT 60
Query: 61 VANPVSRDAQGLVLFDVTGQVRLRHADLEIRLAQDPFPLYPGEVLEKDITPLQVVLPNTA 120
VANPVSRDAQGLVLFDVTGQVRLRHADLEIRLAQDPFPLYPGEVLEKDITPLQVVLPNTA
Sbjct: 61 VANPVSRDAQGLVLFDVTGQVRLRHADLEIRLAQDPFPLYPGEVLEKDITPLQVVLPNTA 120
Query: 121 LHLKALLDFEDKDGDKVVAGDEWLFEGPGTYIPRKEVEVVEIIQATIIRQNQALRLRARK 180
LHLKALLDFEDKDGDKVVAGDEWLFEGPGTYIPRKEVEVVEIIQATIIRQNQALRLRARK
Sbjct: 121 LHLKALLDFEDKDGDKVVAGDEWLFEGPGTYIPRKEVEVVEIIQATIIRQNQALRLRARK 180
Query: 181 ECWDRDGKERVTGEEWLVTTVGAYLPAVFEEVLDLVDAVILTEKTALHLRARRNFRDFRG 240
ECWDRDGKERVTGEEWLVTTVGAYLPAVFEEVLDLVDAVILTEKTALHLRARRNFRDFRG
Sbjct: 181 ECWDRDGKERVTGEEWLVTTVGAYLPAVFEEVLDLVDAVILTEKTALHLRARRNFRDFRG 240
Query: 241 VSRRTGEEWLVTVQDTEAHVPDVHEEVLGVVPITTLGPHNYCVILDPVGPDGKNQLGQKR 300
VSRRTGEEWLVTVQDTEAHVPDVHEEVLGVVPITTLGPHNYCVILDPVGPDGKNQLGQKR
Sbjct: 241 VSRRTGEEWLVTVQDTEAHVPDVHEEVLGVVPITTLGPHNYCVILDPVGPDGKNQLGQKR 300
Query: 301 VVKGEKSFFLQPGEQLEQGIQDVYVLSEQQGLLLRALQPLEEGEDEEKVSHQAGDHWLIR 360
VVKGEKSFFLQPGEQLEQGIQDVYVLSEQQGLLLRALQPLEEGEDEEKVSHQAGDHWLIR
Sbjct: 301 VVKGEKSFFLQPGEQLEQGIQDVYVLSEQQGLLLRALQPLEEGEDEEKVSHQAGDHWLIR 360
Query: 361 GPLEYVPSAKVEVVEERQAIPLDENEGIYVQDVKTGKVRAVIGSTYMLTQDEVLWEKELP 420
GPLEYVPSAKVEVVEERQAIPLDENEGIYVQDVKTGKVRAVIGSTYMLTQDEVLWEKELP
Sbjct: 361 GPLEYVPSAKVEVVEERQAIPLDENEGIYVQDVKTGKVRAVIGSTYMLTQDEVLWEKELP 420
Query: 421 PGVEELLNKGQDPLADRGEKDTAKSLQPLAPRNKTRVVSYRVPHNAAVQVYDYREKRARV 480
PGVEELLNKGQDPLADRGEKDTAKSLQPLAPRNKTRVVSYRVPHNAAVQVYDYREKRARV
Sbjct: 421 PGVEELLNKGQDPLADRGEKDTAKSLQPLAPRNKTRVVSYRVPHNAAVQVYDYREKRARV 480
Query: 481 VFGPELVSLGPEEQFTVLSLSAGRPKRPHARRALCLLLGPDFFTDVITIETADHARLQLQ 540
VFGPELVSLGPEEQFTVLSLSAGRPKRPHARRALCLLLGPDFFTDVITIETADHARLQLQ
Sbjct: 481 VFGPELVSLGPEEQFTVLSLSAGRPKRPHARRALCLLLGPDFFTDVITIETADHARLQLQ 540
Query: 541 LAYNWHFEVNDRKDPQETAKLFSVPDFVGDACKAIASRVRGAVASVTFDDFHKNSARIIR 600
LAYNWHFEVNDRKDPQETAKLFSVPDFVGDACKAIASRVRGAVASVTFDDFHKNSARIIR
Sbjct: 541 LAYNWHFEVNDRKDPQETAKLFSVPDFVGDACKAIASRVRGAVASVTFDDFHKNSARIIR 600
Query: 601 TAVFGFETSEAKGPDGMALPRPRDQAVFPQNGLVVSSVDVQSVEPVDQRTRDALQRSVQL 660
TAVFGFETSEAKGPDGMALPRPRDQAVFPQNGLVVSSVDVQSVEPVDQRTRDALQRSVQL
Sbjct: 601 TAVFGFETSEAKGPDGMALPRPRDQAVFPQNGLVVSSVDVQSVEPVDQRTRDALQRSVQL 660
Query: 661 AIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTG 720
AIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTG
Sbjct: 661 AIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTG 720
Query: 721 TAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELE 780
TAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELE
Sbjct: 721 TAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELE 780
Query: 781 VSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLKSTLITDGSTPIN 840
VSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLKSTLITDGSTPIN
Sbjct: 781 VSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLKSTLITDGSTPIN 840
Query: 841 LFNTAFGLLGMGPEGQPLGRRVASGPSPGEGISPQSAQAPQAPGDNHVVPVLR 893
LFNTAFGLLGMGPEGQPLGRRVASGPSPGEGISPQSAQAPQAPGDNHVVPVLR
Sbjct: 841 LFNTAFGLLGMGPEGQPLGRRVASGPSPGEGISPQSAQAPQAPGDNHVVPVLR 893
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 46.6 bits (109), Expect = 1e-04
Identities = 43/152 (28%), Positives = 76/152 (50%), Gaps = 13/152 (8%)
Query: 648 QRTRDALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKEL 706
Q+ LQ+++Q + + EA A A +EAR + ER EA ++R+++
Sbjct: 2059 QQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER-------EAAQSRRQV 2111
Query: 707 LELEALSMAVESTGTAKAEAESRAEAARIEGEGSV---LQAKLKAQALAIETEAELQRVQ 763
E E L + E A+A+A++ AE R E E QA+ A +AE+++ +
Sbjct: 2112 EEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHK 2171
Query: 764 KVRELELVYARAQLELEVSKAQ-QLAEVEVKK 794
K E + + +AQ+E E++ + QL E + +K
Sbjct: 2172 KFAE-QTLRQKAQVEQELTTLRLQLEETDHQK 2202
Score = 45.4 bits (106), Expect = 2e-04
Identities = 41/154 (26%), Positives = 65/154 (42%), Gaps = 28/154 (18%)
Query: 669 QEAAAKHEAQRLEQEA------RGRLERQKILDQSEAEKARKELLELEALSMAVESTGTA 722
Q++ A+ EA++ ++EA RG+ E Q + + AE+ ELE E T
Sbjct: 1654 QKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQ------ELEKQRQLAEGTAQQ 1707
Query: 723 KAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEV- 781
+ AE R E E Q +L + LA QK +ELE A+ + E+EV
Sbjct: 1708 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL 1767
Query: 782 ---------------SKAQQLAEVEVKKFKQMTE 800
K++Q E E +F+++ E
Sbjct: 1768 LASKARAEEESRSTSEKSKQRLEAEAGRFRELAE 1801
Score = 45.1 bits (105), Expect = 3e-04
Identities = 50/159 (31%), Positives = 75/159 (47%), Gaps = 8/159 (5%)
Query: 648 QRTRDALQRS-VQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQ----SEAEKA 702
+ T A QRS V+ + E +K +A R+E E R + R K Q EAEK
Sbjct: 2215 EATEAARQRSQVEEELFSVRVQMEELSKLKA-RIEAENRALILRDKDNTQRFLQEEAEKM 2273
Query: 703 RKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRV 762
++ E LS+A + + AE R E +L+ K++A A +AE + +
Sbjct: 2274 KQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAE-KMLKEKMQAVQEATRLKAEAELL 2332
Query: 763 QKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEA 801
Q+ +EL AR E + AQQLAE E + F++ EA
Sbjct: 2333 QQQKELAQEQARRLQEDKEQMAQQLAE-ETQGFQRTLEA 2370
Score = 44.3 bits (103), Expect = 5e-04
Identities = 49/189 (25%), Positives = 85/189 (44%), Gaps = 33/189 (17%)
Query: 644 EPVDQRTRDALQRSVQLAIEITTNSQEA--AAKHEAQRLEQEARGRLERQKILDQSE--- 698
E + + R A + + +L ++ SQ A A R++ EA E+Q+ L E
Sbjct: 1483 EEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELR 1542
Query: 699 --AEKARKELLELEA-----LSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQAL 751
AE+A + L + E + +A+E T AEAE +++ A + + L+ L+ + +
Sbjct: 1543 LQAEEAERRLRQAEVERARQVQVALE-TAQRSAEAELQSKRASFAEKTAQLERSLQEEHV 1601
Query: 752 AI-------------ETEAELQRVQKVRELELVYARAQLEL-------EVSKAQQLAEVE 791
A+ + EAE R + RELE +A L EV++ + LA+ E
Sbjct: 1602 AVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAE 1661
Query: 792 VKKFKQMTE 800
+K K+ E
Sbjct: 1662 AEKQKEEAE 1670
Score = 43.5 bits (101), Expect = 9e-04
Identities = 42/156 (26%), Positives = 76/156 (48%), Gaps = 15/156 (9%)
Query: 647 DQRTRDALQR-SVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKE 705
++R R+A +R LA E Q AA E +RL+ + E +++ +++E E AR+
Sbjct: 1980 ERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVE---EARRLRERAEQESARQL 2036
Query: 706 LLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKL-KAQALAIETEAELQRVQK 764
L EA + +AE +A A ++ + LQ L + Q++ + E + ++
Sbjct: 2037 QLAQEA--------AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARR 2088
Query: 765 VRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTE 800
E E AR Q E E +++++ E E ++ KQ E
Sbjct: 2089 AAE-EAEEARVQAEREAAQSRRQVE-EAERLKQSAE 2122
Score = 43.5 bits (101), Expect = 9e-04
Identities = 48/170 (28%), Positives = 81/170 (47%), Gaps = 19/170 (11%)
Query: 641 QSVEPVDQRTR-----DALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILD 695
+ ++ V + TR + LQ+ +LA E QE + AQ+L +E +G Q+ L
Sbjct: 2314 EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDK-EQMAQQLAEETQGF---QRTL- 2368
Query: 696 QSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIET 755
EAE+ R+ + EA + + ++A+A + +A R + + KL LA +
Sbjct: 2369 --EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQE 2426
Query: 756 EA------ELQRVQKVRELE-LVYARAQLELEVSKAQQLAEVEVKKFKQM 798
+ E+QR Q + E L A A+LE E K QQ A++ K ++M
Sbjct: 2427 KVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM 2476
Score = 41.2 bits (95), Expect = 0.004
Identities = 41/140 (29%), Positives = 67/140 (47%), Gaps = 11/140 (7%)
Query: 653 ALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEA 711
AL++ QLA ++Q +A A+ EA+ L+Q + + R++ ++ R EL+
Sbjct: 1368 ALEKQRQLA---EAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQ 1424
Query: 712 LSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELV 771
L + E+ AKA AE +R+ E + +L+ +A E QR EL+ +
Sbjct: 1425 LRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA------TERQRGGAEGELQAL 1478
Query: 772 YARAQLELEVSKAQQLAEVE 791
ARA+ E E K Q E E
Sbjct: 1479 RARAE-EAEAQKRQAQEEAE 1497
Score = 41.2 bits (95), Expect = 0.004
Identities = 47/169 (27%), Positives = 76/169 (44%), Gaps = 13/169 (7%)
Query: 669 QEAAAKHEAQ------RLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTA 722
+E AA+H+A +L + + LERQK L + + R+ E+ AL + E
Sbjct: 1881 EEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAG 1940
Query: 723 KAEAESRAEAARIEGEGSVL---QAKLKAQALAIETEAELQRVQKVRELELVYARAQLEL 779
KAE E R E ++ QA+L+A A + AE +R ++ E E V E
Sbjct: 1941 KAELELELGRIRSNAEDTLRSKEQAELEA-ARQRQLAAEEERRRREAE-ERVQKSLAAEE 1998
Query: 780 EVSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLK 828
E ++ ++ A EV++ K E +R+ A Q++L Q K
Sbjct: 1999 EAARQRKAALEEVERLKAKVEE--ARRLRERAEQESARQLQLAQEAAQK 2045
Score = 40.4 bits (93), Expect = 0.007
Identities = 46/155 (29%), Positives = 70/155 (45%), Gaps = 14/155 (9%)
Query: 648 QRTRDALQ--RSVQLAIEITTNSQEAA-----AKHEAQRLEQEARGRLERQKILDQSEAE 700
Q R+A Q R V+ A + +++E A A+ A++L +EA R+ +Q+
Sbjct: 2099 QAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALR 2158
Query: 701 KARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQAL----AIETE 756
+ + E+E E T KA+ E R++ E + Q L + L A TE
Sbjct: 2159 QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATE 2218
Query: 757 AELQRVQKVRELELVYARAQLELEVSKAQQLAEVE 791
A QR Q E EL R Q+E E+SK + E E
Sbjct: 2219 AARQRSQV--EEELFSVRVQME-ELSKLKARIEAE 2250
Score = 39.7 bits (91), Expect = 0.013
Identities = 43/179 (24%), Positives = 84/179 (46%), Gaps = 20/179 (11%)
Query: 641 QSVEPVDQRTRDALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEA 699
+++E QR + + +L + + S+ +A A+ +AQR ++A E+ + +
Sbjct: 2366 RTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQ 2425
Query: 700 EKARK-ELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAE 758
EK + LE++ ++ +A AE E +++ E +LQ K + + ++ E
Sbjct: 2426 EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSE-EMQTVQQEQL 2484
Query: 759 LQRVQKV-------------RELELVYARAQLEL----EVSKAQQLAEVEVKKFKQMTE 800
LQ Q + RE + +A+LE EV+KAQQL E + ++ +QM +
Sbjct: 2485 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQ 2543
Score = 38.1 bits (87), Expect = 0.037
Identities = 43/180 (23%), Positives = 87/180 (48%), Gaps = 23/180 (12%)
Query: 662 IEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGT 721
+E + + A + E+ A+ + E ++ +++E E R +L EAL + +++
Sbjct: 1592 LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEV 1651
Query: 722 AKAEAESRAEAARIEGEGS-VLQAKLKAQALAI-ETEAELQRVQKVREL----------- 768
A+ ++ ++AEA + + E + + KA+ A+ + E Q ++K R+L
Sbjct: 1652 AQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAA 1711
Query: 769 --ELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAIGPSTIR-----DLAVAGPEMQVKL 821
EL+ RA+ E + + +QL E E+ + ++ EA + R +LA EM+V L
Sbjct: 1712 EQELIRLRAETE-QGEQQRQLLEEELARLQR--EAAAATQKRQELEAELAKVRAEMEVLL 1768
Score = 35.8 bits (81), Expect = 0.18
Identities = 26/120 (21%), Positives = 56/120 (46%), Gaps = 4/120 (3%)
Query: 683 EARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVL 742
E R+E ++ L + + + R+ L E+EA A A+A+++AE E + +
Sbjct: 1339 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1398
Query: 743 QAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAI 802
+ ++ + A++ + + + +Q+ EL R E E+ + AE + ++ E I
Sbjct: 1399 EEVVRREEAAVDAQQQKRSIQE----ELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEI 1454
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 46.6 bits (109), Expect = 1e-04
Identities = 43/152 (28%), Positives = 76/152 (50%), Gaps = 13/152 (8%)
Query: 648 QRTRDALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKEL 706
Q+ LQ+++Q + + EA A A +EAR + ER EA ++R+++
Sbjct: 2063 QQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER-------EAAQSRRQV 2115
Query: 707 LELEALSMAVESTGTAKAEAESRAEAARIEGEGSV---LQAKLKAQALAIETEAELQRVQ 763
E E L + E A+A+A++ AE R E E QA+ A +AE+++ +
Sbjct: 2116 EEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHK 2175
Query: 764 KVRELELVYARAQLELEVSKAQ-QLAEVEVKK 794
K E + + +AQ+E E++ + QL E + +K
Sbjct: 2176 KFAE-QTLRQKAQVEQELTTLRLQLEETDHQK 2206
Score = 45.4 bits (106), Expect = 2e-04
Identities = 41/154 (26%), Positives = 65/154 (42%), Gaps = 28/154 (18%)
Query: 669 QEAAAKHEAQRLEQEA------RGRLERQKILDQSEAEKARKELLELEALSMAVESTGTA 722
Q++ A+ EA++ ++EA RG+ E Q + + AE+ ELE E T
Sbjct: 1658 QKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQ------ELEKQRQLAEGTAQQ 1711
Query: 723 KAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEV- 781
+ AE R E E Q +L + LA QK +ELE A+ + E+EV
Sbjct: 1712 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL 1771
Query: 782 ---------------SKAQQLAEVEVKKFKQMTE 800
K++Q E E +F+++ E
Sbjct: 1772 LASKARAEEESRSTSEKSKQRLEAEAGRFRELAE 1805
Score = 45.1 bits (105), Expect = 3e-04
Identities = 50/159 (31%), Positives = 75/159 (47%), Gaps = 8/159 (5%)
Query: 648 QRTRDALQRS-VQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQ----SEAEKA 702
+ T A QRS V+ + E +K +A R+E E R + R K Q EAEK
Sbjct: 2219 EATEAARQRSQVEEELFSVRVQMEELSKLKA-RIEAENRALILRDKDNTQRFLQEEAEKM 2277
Query: 703 RKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRV 762
++ E LS+A + + AE R E +L+ K++A A +AE + +
Sbjct: 2278 KQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAE-KMLKEKMQAVQEATRLKAEAELL 2336
Query: 763 QKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEA 801
Q+ +EL AR E + AQQLAE E + F++ EA
Sbjct: 2337 QQQKELAQEQARRLQEDKEQMAQQLAE-ETQGFQRTLEA 2374
Score = 44.3 bits (103), Expect = 5e-04
Identities = 49/189 (25%), Positives = 85/189 (44%), Gaps = 33/189 (17%)
Query: 644 EPVDQRTRDALQRSVQLAIEITTNSQEA--AAKHEAQRLEQEARGRLERQKILDQSE--- 698
E + + R A + + +L ++ SQ A A R++ EA E+Q+ L E
Sbjct: 1487 EEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELR 1546
Query: 699 --AEKARKELLELEA-----LSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQAL 751
AE+A + L + E + +A+E T AEAE +++ A + + L+ L+ + +
Sbjct: 1547 LQAEEAERRLRQAEVERARQVQVALE-TAQRSAEAELQSKRASFAEKTAQLERSLQEEHV 1605
Query: 752 AI-------------ETEAELQRVQKVRELELVYARAQLEL-------EVSKAQQLAEVE 791
A+ + EAE R + RELE +A L EV++ + LA+ E
Sbjct: 1606 AVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAE 1665
Query: 792 VKKFKQMTE 800
+K K+ E
Sbjct: 1666 AEKQKEEAE 1674
Score = 43.5 bits (101), Expect = 9e-04
Identities = 42/156 (26%), Positives = 76/156 (48%), Gaps = 15/156 (9%)
Query: 647 DQRTRDALQR-SVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKE 705
++R R+A +R LA E Q AA E +RL+ + E +++ +++E E AR+
Sbjct: 1984 ERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVE---EARRLRERAEQESARQL 2040
Query: 706 LLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKL-KAQALAIETEAELQRVQK 764
L EA + +AE +A A ++ + LQ L + Q++ + E + ++
Sbjct: 2041 QLAQEA--------AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARR 2092
Query: 765 VRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTE 800
E E AR Q E E +++++ E E ++ KQ E
Sbjct: 2093 AAE-EAEEARVQAEREAAQSRRQVE-EAERLKQSAE 2126
Score = 43.5 bits (101), Expect = 9e-04
Identities = 48/170 (28%), Positives = 81/170 (47%), Gaps = 19/170 (11%)
Query: 641 QSVEPVDQRTR-----DALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILD 695
+ ++ V + TR + LQ+ +LA E QE + AQ+L +E +G Q+ L
Sbjct: 2318 EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDK-EQMAQQLAEETQGF---QRTL- 2372
Query: 696 QSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIET 755
EAE+ R+ + EA + + ++A+A + +A R + + KL LA +
Sbjct: 2373 --EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQE 2430
Query: 756 EA------ELQRVQKVRELE-LVYARAQLELEVSKAQQLAEVEVKKFKQM 798
+ E+QR Q + E L A A+LE E K QQ A++ K ++M
Sbjct: 2431 KVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM 2480
Score = 41.2 bits (95), Expect = 0.004
Identities = 41/140 (29%), Positives = 67/140 (47%), Gaps = 11/140 (7%)
Query: 653 ALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEA 711
AL++ QLA ++Q +A A+ EA+ L+Q + + R++ ++ R EL+
Sbjct: 1372 ALEKQRQLA---EAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQ 1428
Query: 712 LSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELV 771
L + E+ AKA AE +R+ E + +L+ +A E QR EL+ +
Sbjct: 1429 LRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA------TERQRGGAEGELQAL 1482
Query: 772 YARAQLELEVSKAQQLAEVE 791
ARA+ E E K Q E E
Sbjct: 1483 RARAE-EAEAQKRQAQEEAE 1501
Score = 41.2 bits (95), Expect = 0.004
Identities = 47/169 (27%), Positives = 76/169 (44%), Gaps = 13/169 (7%)
Query: 669 QEAAAKHEAQ------RLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTA 722
+E AA+H+A +L + + LERQK L + + R+ E+ AL + E
Sbjct: 1885 EEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAG 1944
Query: 723 KAEAESRAEAARIEGEGSVL---QAKLKAQALAIETEAELQRVQKVRELELVYARAQLEL 779
KAE E R E ++ QA+L+A A + AE +R ++ E E V E
Sbjct: 1945 KAELELELGRIRSNAEDTLRSKEQAELEA-ARQRQLAAEEERRRREAE-ERVQKSLAAEE 2002
Query: 780 EVSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLK 828
E ++ ++ A EV++ K E +R+ A Q++L Q K
Sbjct: 2003 EAARQRKAALEEVERLKAKVEE--ARRLRERAEQESARQLQLAQEAAQK 2049
Score = 40.4 bits (93), Expect = 0.007
Identities = 46/155 (29%), Positives = 70/155 (45%), Gaps = 14/155 (9%)
Query: 648 QRTRDALQ--RSVQLAIEITTNSQEAA-----AKHEAQRLEQEARGRLERQKILDQSEAE 700
Q R+A Q R V+ A + +++E A A+ A++L +EA R+ +Q+
Sbjct: 2103 QAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALR 2162
Query: 701 KARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQAL----AIETE 756
+ + E+E E T KA+ E R++ E + Q L + L A TE
Sbjct: 2163 QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATE 2222
Query: 757 AELQRVQKVRELELVYARAQLELEVSKAQQLAEVE 791
A QR Q E EL R Q+E E+SK + E E
Sbjct: 2223 AARQRSQV--EEELFSVRVQME-ELSKLKARIEAE 2254
Score = 39.7 bits (91), Expect = 0.013
Identities = 43/179 (24%), Positives = 84/179 (46%), Gaps = 20/179 (11%)
Query: 641 QSVEPVDQRTRDALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEA 699
+++E QR + + +L + + S+ +A A+ +AQR ++A E+ + +
Sbjct: 2370 RTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQ 2429
Query: 700 EKARK-ELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAE 758
EK + LE++ ++ +A AE E +++ E +LQ K + + ++ E
Sbjct: 2430 EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSE-EMQTVQQEQL 2488
Query: 759 LQRVQKV-------------RELELVYARAQLEL----EVSKAQQLAEVEVKKFKQMTE 800
LQ Q + RE + +A+LE EV+KAQQL E + ++ +QM +
Sbjct: 2489 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQ 2547
Score = 38.1 bits (87), Expect = 0.037
Identities = 43/180 (23%), Positives = 87/180 (48%), Gaps = 23/180 (12%)
Query: 662 IEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGT 721
+E + + A + E+ A+ + E ++ +++E E R +L EAL + +++
Sbjct: 1596 LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEV 1655
Query: 722 AKAEAESRAEAARIEGEGS-VLQAKLKAQALAI-ETEAELQRVQKVREL----------- 768
A+ ++ ++AEA + + E + + KA+ A+ + E Q ++K R+L
Sbjct: 1656 AQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAA 1715
Query: 769 --ELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAIGPSTIR-----DLAVAGPEMQVKL 821
EL+ RA+ E + + +QL E E+ + ++ EA + R +LA EM+V L
Sbjct: 1716 EQELIRLRAETE-QGEQQRQLLEEELARLQR--EAAAATQKRQELEAELAKVRAEMEVLL 1772
Score = 35.8 bits (81), Expect = 0.18
Identities = 26/120 (21%), Positives = 56/120 (46%), Gaps = 4/120 (3%)
Query: 683 EARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVL 742
E R+E ++ L + + + R+ L E+EA A A+A+++AE E + +
Sbjct: 1343 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1402
Query: 743 QAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAI 802
+ ++ + A++ + + + +Q+ EL R E E+ + AE + ++ E I
Sbjct: 1403 EEVVRREEAAVDAQQQKRSIQE----ELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEI 1458
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 46.6 bits (109), Expect = 1e-04
Identities = 43/152 (28%), Positives = 76/152 (50%), Gaps = 13/152 (8%)
Query: 648 QRTRDALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKEL 706
Q+ LQ+++Q + + EA A A +EAR + ER EA ++R+++
Sbjct: 2059 QQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER-------EAAQSRRQV 2111
Query: 707 LELEALSMAVESTGTAKAEAESRAEAARIEGEGSV---LQAKLKAQALAIETEAELQRVQ 763
E E L + E A+A+A++ AE R E E QA+ A +AE+++ +
Sbjct: 2112 EEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHK 2171
Query: 764 KVRELELVYARAQLELEVSKAQ-QLAEVEVKK 794
K E + + +AQ+E E++ + QL E + +K
Sbjct: 2172 KFAE-QTLRQKAQVEQELTTLRLQLEETDHQK 2202
Score = 45.4 bits (106), Expect = 2e-04
Identities = 41/154 (26%), Positives = 65/154 (42%), Gaps = 28/154 (18%)
Query: 669 QEAAAKHEAQRLEQEA------RGRLERQKILDQSEAEKARKELLELEALSMAVESTGTA 722
Q++ A+ EA++ ++EA RG+ E Q + + AE+ ELE E T
Sbjct: 1654 QKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQ------ELEKQRQLAEGTAQQ 1707
Query: 723 KAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEV- 781
+ AE R E E Q +L + LA QK +ELE A+ + E+EV
Sbjct: 1708 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL 1767
Query: 782 ---------------SKAQQLAEVEVKKFKQMTE 800
K++Q E E +F+++ E
Sbjct: 1768 LASKARAEEESRSTSEKSKQRLEAEAGRFRELAE 1801
Score = 45.1 bits (105), Expect = 3e-04
Identities = 50/159 (31%), Positives = 75/159 (47%), Gaps = 8/159 (5%)
Query: 648 QRTRDALQRS-VQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQ----SEAEKA 702
+ T A QRS V+ + E +K +A R+E E R + R K Q EAEK
Sbjct: 2215 EATEAARQRSQVEEELFSVRVQMEELSKLKA-RIEAENRALILRDKDNTQRFLQEEAEKM 2273
Query: 703 RKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRV 762
++ E LS+A + + AE R E +L+ K++A A +AE + +
Sbjct: 2274 KQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAE-KMLKEKMQAVQEATRLKAEAELL 2332
Query: 763 QKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEA 801
Q+ +EL AR E + AQQLAE E + F++ EA
Sbjct: 2333 QQQKELAQEQARRLQEDKEQMAQQLAE-ETQGFQRTLEA 2370
Score = 44.3 bits (103), Expect = 5e-04
Identities = 49/189 (25%), Positives = 85/189 (44%), Gaps = 33/189 (17%)
Query: 644 EPVDQRTRDALQRSVQLAIEITTNSQEA--AAKHEAQRLEQEARGRLERQKILDQSE--- 698
E + + R A + + +L ++ SQ A A R++ EA E+Q+ L E
Sbjct: 1483 EEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELR 1542
Query: 699 --AEKARKELLELEA-----LSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQAL 751
AE+A + L + E + +A+E T AEAE +++ A + + L+ L+ + +
Sbjct: 1543 LQAEEAERRLRQAEVERARQVQVALE-TAQRSAEAELQSKRASFAEKTAQLERSLQEEHV 1601
Query: 752 AI-------------ETEAELQRVQKVRELELVYARAQLEL-------EVSKAQQLAEVE 791
A+ + EAE R + RELE +A L EV++ + LA+ E
Sbjct: 1602 AVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAE 1661
Query: 792 VKKFKQMTE 800
+K K+ E
Sbjct: 1662 AEKQKEEAE 1670
Score = 43.5 bits (101), Expect = 9e-04
Identities = 42/156 (26%), Positives = 76/156 (48%), Gaps = 15/156 (9%)
Query: 647 DQRTRDALQR-SVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKE 705
++R R+A +R LA E Q AA E +RL+ + E +++ +++E E AR+
Sbjct: 1980 ERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVE---EARRLRERAEQESARQL 2036
Query: 706 LLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKL-KAQALAIETEAELQRVQK 764
L EA + +AE +A A ++ + LQ L + Q++ + E + ++
Sbjct: 2037 QLAQEA--------AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARR 2088
Query: 765 VRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTE 800
E E AR Q E E +++++ E E ++ KQ E
Sbjct: 2089 AAE-EAEEARVQAEREAAQSRRQVE-EAERLKQSAE 2122
Score = 43.5 bits (101), Expect = 9e-04
Identities = 48/170 (28%), Positives = 81/170 (47%), Gaps = 19/170 (11%)
Query: 641 QSVEPVDQRTR-----DALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILD 695
+ ++ V + TR + LQ+ +LA E QE + AQ+L +E +G Q+ L
Sbjct: 2314 EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDK-EQMAQQLAEETQGF---QRTL- 2368
Query: 696 QSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIET 755
EAE+ R+ + EA + + ++A+A + +A R + + KL LA +
Sbjct: 2369 --EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQE 2426
Query: 756 EA------ELQRVQKVRELE-LVYARAQLELEVSKAQQLAEVEVKKFKQM 798
+ E+QR Q + E L A A+LE E K QQ A++ K ++M
Sbjct: 2427 KVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM 2476
Score = 41.2 bits (95), Expect = 0.004
Identities = 41/140 (29%), Positives = 67/140 (47%), Gaps = 11/140 (7%)
Query: 653 ALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEA 711
AL++ QLA ++Q +A A+ EA+ L+Q + + R++ ++ R EL+
Sbjct: 1368 ALEKQRQLA---EAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQ 1424
Query: 712 LSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELV 771
L + E+ AKA AE +R+ E + +L+ +A E QR EL+ +
Sbjct: 1425 LRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA------TERQRGGAEGELQAL 1478
Query: 772 YARAQLELEVSKAQQLAEVE 791
ARA+ E E K Q E E
Sbjct: 1479 RARAE-EAEAQKRQAQEEAE 1497
Score = 41.2 bits (95), Expect = 0.004
Identities = 47/169 (27%), Positives = 76/169 (44%), Gaps = 13/169 (7%)
Query: 669 QEAAAKHEAQ------RLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTA 722
+E AA+H+A +L + + LERQK L + + R+ E+ AL + E
Sbjct: 1881 EEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAG 1940
Query: 723 KAEAESRAEAARIEGEGSVL---QAKLKAQALAIETEAELQRVQKVRELELVYARAQLEL 779
KAE E R E ++ QA+L+A A + AE +R ++ E E V E
Sbjct: 1941 KAELELELGRIRSNAEDTLRSKEQAELEA-ARQRQLAAEEERRRREAE-ERVQKSLAAEE 1998
Query: 780 EVSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLK 828
E ++ ++ A EV++ K E +R+ A Q++L Q K
Sbjct: 1999 EAARQRKAALEEVERLKAKVEE--ARRLRERAEQESARQLQLAQEAAQK 2045
Score = 40.4 bits (93), Expect = 0.007
Identities = 46/155 (29%), Positives = 70/155 (45%), Gaps = 14/155 (9%)
Query: 648 QRTRDALQ--RSVQLAIEITTNSQEAA-----AKHEAQRLEQEARGRLERQKILDQSEAE 700
Q R+A Q R V+ A + +++E A A+ A++L +EA R+ +Q+
Sbjct: 2099 QAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALR 2158
Query: 701 KARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQAL----AIETE 756
+ + E+E E T KA+ E R++ E + Q L + L A TE
Sbjct: 2159 QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATE 2218
Query: 757 AELQRVQKVRELELVYARAQLELEVSKAQQLAEVE 791
A QR Q E EL R Q+E E+SK + E E
Sbjct: 2219 AARQRSQV--EEELFSVRVQME-ELSKLKARIEAE 2250
Score = 39.7 bits (91), Expect = 0.013
Identities = 43/179 (24%), Positives = 84/179 (46%), Gaps = 20/179 (11%)
Query: 641 QSVEPVDQRTRDALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEA 699
+++E QR + + +L + + S+ +A A+ +AQR ++A E+ + +
Sbjct: 2366 RTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQ 2425
Query: 700 EKARK-ELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAE 758
EK + LE++ ++ +A AE E +++ E +LQ K + + ++ E
Sbjct: 2426 EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSE-EMQTVQQEQL 2484
Query: 759 LQRVQKV-------------RELELVYARAQLEL----EVSKAQQLAEVEVKKFKQMTE 800
LQ Q + RE + +A+LE EV+KAQQL E + ++ +QM +
Sbjct: 2485 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQ 2543
Score = 38.1 bits (87), Expect = 0.037
Identities = 43/180 (23%), Positives = 87/180 (48%), Gaps = 23/180 (12%)
Query: 662 IEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGT 721
+E + + A + E+ A+ + E ++ +++E E R +L EAL + +++
Sbjct: 1592 LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEV 1651
Query: 722 AKAEAESRAEAARIEGEGS-VLQAKLKAQALAI-ETEAELQRVQKVREL----------- 768
A+ ++ ++AEA + + E + + KA+ A+ + E Q ++K R+L
Sbjct: 1652 AQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAA 1711
Query: 769 --ELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAIGPSTIR-----DLAVAGPEMQVKL 821
EL+ RA+ E + + +QL E E+ + ++ EA + R +LA EM+V L
Sbjct: 1712 EQELIRLRAETE-QGEQQRQLLEEELARLQR--EAAAATQKRQELEAELAKVRAEMEVLL 1768
Score = 35.8 bits (81), Expect = 0.18
Identities = 26/120 (21%), Positives = 56/120 (46%), Gaps = 4/120 (3%)
Query: 683 EARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVL 742
E R+E ++ L + + + R+ L E+EA A A+A+++AE E + +
Sbjct: 1339 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1398
Query: 743 QAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAI 802
+ ++ + A++ + + + +Q+ EL R E E+ + AE + ++ E I
Sbjct: 1399 EEVVRREEAAVDAQQQKRSIQE----ELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEI 1454
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 46.6 bits (109), Expect = 1e-04
Identities = 43/152 (28%), Positives = 76/152 (50%), Gaps = 13/152 (8%)
Query: 648 QRTRDALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKEL 706
Q+ LQ+++Q + + EA A A +EAR + ER EA ++R+++
Sbjct: 2027 QQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER-------EAAQSRRQV 2079
Query: 707 LELEALSMAVESTGTAKAEAESRAEAARIEGEGSV---LQAKLKAQALAIETEAELQRVQ 763
E E L + E A+A+A++ AE R E E QA+ A +AE+++ +
Sbjct: 2080 EEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHK 2139
Query: 764 KVRELELVYARAQLELEVSKAQ-QLAEVEVKK 794
K E + + +AQ+E E++ + QL E + +K
Sbjct: 2140 KFAE-QTLRQKAQVEQELTTLRLQLEETDHQK 2170
Score = 45.4 bits (106), Expect = 2e-04
Identities = 41/154 (26%), Positives = 65/154 (42%), Gaps = 28/154 (18%)
Query: 669 QEAAAKHEAQRLEQEA------RGRLERQKILDQSEAEKARKELLELEALSMAVESTGTA 722
Q++ A+ EA++ ++EA RG+ E Q + + AE+ ELE E T
Sbjct: 1622 QKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQ------ELEKQRQLAEGTAQQ 1675
Query: 723 KAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEV- 781
+ AE R E E Q +L + LA QK +ELE A+ + E+EV
Sbjct: 1676 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL 1735
Query: 782 ---------------SKAQQLAEVEVKKFKQMTE 800
K++Q E E +F+++ E
Sbjct: 1736 LASKARAEEESRSTSEKSKQRLEAEAGRFRELAE 1769
Score = 45.1 bits (105), Expect = 3e-04
Identities = 50/159 (31%), Positives = 75/159 (47%), Gaps = 8/159 (5%)
Query: 648 QRTRDALQRS-VQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQ----SEAEKA 702
+ T A QRS V+ + E +K +A R+E E R + R K Q EAEK
Sbjct: 2183 EATEAARQRSQVEEELFSVRVQMEELSKLKA-RIEAENRALILRDKDNTQRFLQEEAEKM 2241
Query: 703 RKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRV 762
++ E LS+A + + AE R E +L+ K++A A +AE + +
Sbjct: 2242 KQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAE-KMLKEKMQAVQEATRLKAEAELL 2300
Query: 763 QKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEA 801
Q+ +EL AR E + AQQLAE E + F++ EA
Sbjct: 2301 QQQKELAQEQARRLQEDKEQMAQQLAE-ETQGFQRTLEA 2338
Score = 44.3 bits (103), Expect = 5e-04
Identities = 49/189 (25%), Positives = 85/189 (44%), Gaps = 33/189 (17%)
Query: 644 EPVDQRTRDALQRSVQLAIEITTNSQEA--AAKHEAQRLEQEARGRLERQKILDQSE--- 698
E + + R A + + +L ++ SQ A A R++ EA E+Q+ L E
Sbjct: 1451 EEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELR 1510
Query: 699 --AEKARKELLELEA-----LSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQAL 751
AE+A + L + E + +A+E T AEAE +++ A + + L+ L+ + +
Sbjct: 1511 LQAEEAERRLRQAEVERARQVQVALE-TAQRSAEAELQSKRASFAEKTAQLERSLQEEHV 1569
Query: 752 AI-------------ETEAELQRVQKVRELELVYARAQLEL-------EVSKAQQLAEVE 791
A+ + EAE R + RELE +A L EV++ + LA+ E
Sbjct: 1570 AVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAE 1629
Query: 792 VKKFKQMTE 800
+K K+ E
Sbjct: 1630 AEKQKEEAE 1638
Score = 43.5 bits (101), Expect = 9e-04
Identities = 42/156 (26%), Positives = 76/156 (48%), Gaps = 15/156 (9%)
Query: 647 DQRTRDALQR-SVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKE 705
++R R+A +R LA E Q AA E +RL+ + E +++ +++E E AR+
Sbjct: 1948 ERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVE---EARRLRERAEQESARQL 2004
Query: 706 LLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKL-KAQALAIETEAELQRVQK 764
L EA + +AE +A A ++ + LQ L + Q++ + E + ++
Sbjct: 2005 QLAQEA--------AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARR 2056
Query: 765 VRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTE 800
E E AR Q E E +++++ E E ++ KQ E
Sbjct: 2057 AAE-EAEEARVQAEREAAQSRRQVE-EAERLKQSAE 2090
Score = 43.5 bits (101), Expect = 9e-04
Identities = 48/170 (28%), Positives = 81/170 (47%), Gaps = 19/170 (11%)
Query: 641 QSVEPVDQRTR-----DALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILD 695
+ ++ V + TR + LQ+ +LA E QE + AQ+L +E +G Q+ L
Sbjct: 2282 EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDK-EQMAQQLAEETQGF---QRTL- 2336
Query: 696 QSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIET 755
EAE+ R+ + EA + + ++A+A + +A R + + KL LA +
Sbjct: 2337 --EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQE 2394
Query: 756 EA------ELQRVQKVRELE-LVYARAQLELEVSKAQQLAEVEVKKFKQM 798
+ E+QR Q + E L A A+LE E K QQ A++ K ++M
Sbjct: 2395 KVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM 2444
Score = 41.2 bits (95), Expect = 0.004
Identities = 41/140 (29%), Positives = 67/140 (47%), Gaps = 11/140 (7%)
Query: 653 ALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEA 711
AL++ QLA ++Q +A A+ EA+ L+Q + + R++ ++ R EL+
Sbjct: 1336 ALEKQRQLA---EAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQ 1392
Query: 712 LSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELV 771
L + E+ AKA AE +R+ E + +L+ +A E QR EL+ +
Sbjct: 1393 LRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA------TERQRGGAEGELQAL 1446
Query: 772 YARAQLELEVSKAQQLAEVE 791
ARA+ E E K Q E E
Sbjct: 1447 RARAE-EAEAQKRQAQEEAE 1465
Score = 41.2 bits (95), Expect = 0.004
Identities = 47/169 (27%), Positives = 76/169 (44%), Gaps = 13/169 (7%)
Query: 669 QEAAAKHEAQ------RLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTA 722
+E AA+H+A +L + + LERQK L + + R+ E+ AL + E
Sbjct: 1849 EEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAG 1908
Query: 723 KAEAESRAEAARIEGEGSVL---QAKLKAQALAIETEAELQRVQKVRELELVYARAQLEL 779
KAE E R E ++ QA+L+A A + AE +R ++ E E V E
Sbjct: 1909 KAELELELGRIRSNAEDTLRSKEQAELEA-ARQRQLAAEEERRRREAE-ERVQKSLAAEE 1966
Query: 780 EVSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLK 828
E ++ ++ A EV++ K E +R+ A Q++L Q K
Sbjct: 1967 EAARQRKAALEEVERLKAKVEE--ARRLRERAEQESARQLQLAQEAAQK 2013
Score = 40.4 bits (93), Expect = 0.007
Identities = 46/155 (29%), Positives = 70/155 (45%), Gaps = 14/155 (9%)
Query: 648 QRTRDALQ--RSVQLAIEITTNSQEAA-----AKHEAQRLEQEARGRLERQKILDQSEAE 700
Q R+A Q R V+ A + +++E A A+ A++L +EA R+ +Q+
Sbjct: 2067 QAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALR 2126
Query: 701 KARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQAL----AIETE 756
+ + E+E E T KA+ E R++ E + Q L + L A TE
Sbjct: 2127 QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATE 2186
Query: 757 AELQRVQKVRELELVYARAQLELEVSKAQQLAEVE 791
A QR Q E EL R Q+E E+SK + E E
Sbjct: 2187 AARQRSQV--EEELFSVRVQME-ELSKLKARIEAE 2218
Score = 39.7 bits (91), Expect = 0.013
Identities = 43/179 (24%), Positives = 84/179 (46%), Gaps = 20/179 (11%)
Query: 641 QSVEPVDQRTRDALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEA 699
+++E QR + + +L + + S+ +A A+ +AQR ++A E+ + +
Sbjct: 2334 RTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQ 2393
Query: 700 EKARK-ELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAE 758
EK + LE++ ++ +A AE E +++ E +LQ K + + ++ E
Sbjct: 2394 EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSE-EMQTVQQEQL 2452
Query: 759 LQRVQKV-------------RELELVYARAQLEL----EVSKAQQLAEVEVKKFKQMTE 800
LQ Q + RE + +A+LE EV+KAQQL E + ++ +QM +
Sbjct: 2453 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQ 2511
Score = 38.1 bits (87), Expect = 0.037
Identities = 43/180 (23%), Positives = 87/180 (48%), Gaps = 23/180 (12%)
Query: 662 IEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGT 721
+E + + A + E+ A+ + E ++ +++E E R +L EAL + +++
Sbjct: 1560 LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEV 1619
Query: 722 AKAEAESRAEAARIEGEGS-VLQAKLKAQALAI-ETEAELQRVQKVREL----------- 768
A+ ++ ++AEA + + E + + KA+ A+ + E Q ++K R+L
Sbjct: 1620 AQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAA 1679
Query: 769 --ELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAIGPSTIR-----DLAVAGPEMQVKL 821
EL+ RA+ E + + +QL E E+ + ++ EA + R +LA EM+V L
Sbjct: 1680 EQELIRLRAETE-QGEQQRQLLEEELARLQR--EAAAATQKRQELEAELAKVRAEMEVLL 1736
Score = 35.8 bits (81), Expect = 0.18
Identities = 26/120 (21%), Positives = 56/120 (46%), Gaps = 4/120 (3%)
Query: 683 EARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVL 742
E R+E ++ L + + + R+ L E+EA A A+A+++AE E + +
Sbjct: 1307 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1366
Query: 743 QAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAI 802
+ ++ + A++ + + + +Q+ EL R E E+ + AE + ++ E I
Sbjct: 1367 EEVVRREEAAVDAQQQKRSIQE----ELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEI 1422
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 46.6 bits (109), Expect = 1e-04
Identities = 43/152 (28%), Positives = 76/152 (50%), Gaps = 13/152 (8%)
Query: 648 QRTRDALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKEL 706
Q+ LQ+++Q + + EA A A +EAR + ER EA ++R+++
Sbjct: 2196 QQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER-------EAAQSRRQV 2248
Query: 707 LELEALSMAVESTGTAKAEAESRAEAARIEGEGSV---LQAKLKAQALAIETEAELQRVQ 763
E E L + E A+A+A++ AE R E E QA+ A +AE+++ +
Sbjct: 2249 EEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHK 2308
Query: 764 KVRELELVYARAQLELEVSKAQ-QLAEVEVKK 794
K E + + +AQ+E E++ + QL E + +K
Sbjct: 2309 KFAE-QTLRQKAQVEQELTTLRLQLEETDHQK 2339
Score = 45.4 bits (106), Expect = 2e-04
Identities = 41/154 (26%), Positives = 65/154 (42%), Gaps = 28/154 (18%)
Query: 669 QEAAAKHEAQRLEQEA------RGRLERQKILDQSEAEKARKELLELEALSMAVESTGTA 722
Q++ A+ EA++ ++EA RG+ E Q + + AE+ ELE E T
Sbjct: 1791 QKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQ------ELEKQRQLAEGTAQQ 1844
Query: 723 KAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEV- 781
+ AE R E E Q +L + LA QK +ELE A+ + E+EV
Sbjct: 1845 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL 1904
Query: 782 ---------------SKAQQLAEVEVKKFKQMTE 800
K++Q E E +F+++ E
Sbjct: 1905 LASKARAEEESRSTSEKSKQRLEAEAGRFRELAE 1938
Score = 45.1 bits (105), Expect = 3e-04
Identities = 50/159 (31%), Positives = 75/159 (47%), Gaps = 8/159 (5%)
Query: 648 QRTRDALQRS-VQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQ----SEAEKA 702
+ T A QRS V+ + E +K +A R+E E R + R K Q EAEK
Sbjct: 2352 EATEAARQRSQVEEELFSVRVQMEELSKLKA-RIEAENRALILRDKDNTQRFLQEEAEKM 2410
Query: 703 RKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRV 762
++ E LS+A + + AE R E +L+ K++A A +AE + +
Sbjct: 2411 KQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAE-KMLKEKMQAVQEATRLKAEAELL 2469
Query: 763 QKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEA 801
Q+ +EL AR E + AQQLAE E + F++ EA
Sbjct: 2470 QQQKELAQEQARRLQEDKEQMAQQLAE-ETQGFQRTLEA 2507
Score = 44.3 bits (103), Expect = 5e-04
Identities = 49/189 (25%), Positives = 85/189 (44%), Gaps = 33/189 (17%)
Query: 644 EPVDQRTRDALQRSVQLAIEITTNSQEA--AAKHEAQRLEQEARGRLERQKILDQSE--- 698
E + + R A + + +L ++ SQ A A R++ EA E+Q+ L E
Sbjct: 1620 EEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELR 1679
Query: 699 --AEKARKELLELEA-----LSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQAL 751
AE+A + L + E + +A+E T AEAE +++ A + + L+ L+ + +
Sbjct: 1680 LQAEEAERRLRQAEVERARQVQVALE-TAQRSAEAELQSKRASFAEKTAQLERSLQEEHV 1738
Query: 752 AI-------------ETEAELQRVQKVRELELVYARAQLEL-------EVSKAQQLAEVE 791
A+ + EAE R + RELE +A L EV++ + LA+ E
Sbjct: 1739 AVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAE 1798
Query: 792 VKKFKQMTE 800
+K K+ E
Sbjct: 1799 AEKQKEEAE 1807
Score = 43.5 bits (101), Expect = 9e-04
Identities = 42/156 (26%), Positives = 76/156 (48%), Gaps = 15/156 (9%)
Query: 647 DQRTRDALQR-SVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKE 705
++R R+A +R LA E Q AA E +RL+ + E +++ +++E E AR+
Sbjct: 2117 ERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVE---EARRLRERAEQESARQL 2173
Query: 706 LLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKL-KAQALAIETEAELQRVQK 764
L EA + +AE +A A ++ + LQ L + Q++ + E + ++
Sbjct: 2174 QLAQEA--------AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARR 2225
Query: 765 VRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTE 800
E E AR Q E E +++++ E E ++ KQ E
Sbjct: 2226 AAE-EAEEARVQAEREAAQSRRQVE-EAERLKQSAE 2259
Score = 43.5 bits (101), Expect = 9e-04
Identities = 48/170 (28%), Positives = 81/170 (47%), Gaps = 19/170 (11%)
Query: 641 QSVEPVDQRTR-----DALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILD 695
+ ++ V + TR + LQ+ +LA E QE + AQ+L +E +G Q+ L
Sbjct: 2451 EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDK-EQMAQQLAEETQGF---QRTL- 2505
Query: 696 QSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIET 755
EAE+ R+ + EA + + ++A+A + +A R + + KL LA +
Sbjct: 2506 --EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQE 2563
Query: 756 EA------ELQRVQKVRELE-LVYARAQLELEVSKAQQLAEVEVKKFKQM 798
+ E+QR Q + E L A A+LE E K QQ A++ K ++M
Sbjct: 2564 KVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM 2613
Score = 41.2 bits (95), Expect = 0.004
Identities = 41/140 (29%), Positives = 67/140 (47%), Gaps = 11/140 (7%)
Query: 653 ALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEA 711
AL++ QLA ++Q +A A+ EA+ L+Q + + R++ ++ R EL+
Sbjct: 1505 ALEKQRQLA---EAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQ 1561
Query: 712 LSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELV 771
L + E+ AKA AE +R+ E + +L+ +A E QR EL+ +
Sbjct: 1562 LRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA------TERQRGGAEGELQAL 1615
Query: 772 YARAQLELEVSKAQQLAEVE 791
ARA+ E E K Q E E
Sbjct: 1616 RARAE-EAEAQKRQAQEEAE 1634
Score = 41.2 bits (95), Expect = 0.004
Identities = 47/169 (27%), Positives = 76/169 (44%), Gaps = 13/169 (7%)
Query: 669 QEAAAKHEAQ------RLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTA 722
+E AA+H+A +L + + LERQK L + + R+ E+ AL + E
Sbjct: 2018 EEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAG 2077
Query: 723 KAEAESRAEAARIEGEGSVL---QAKLKAQALAIETEAELQRVQKVRELELVYARAQLEL 779
KAE E R E ++ QA+L+A A + AE +R ++ E E V E
Sbjct: 2078 KAELELELGRIRSNAEDTLRSKEQAELEA-ARQRQLAAEEERRRREAE-ERVQKSLAAEE 2135
Query: 780 EVSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLK 828
E ++ ++ A EV++ K E +R+ A Q++L Q K
Sbjct: 2136 EAARQRKAALEEVERLKAKVEE--ARRLRERAEQESARQLQLAQEAAQK 2182
Score = 40.4 bits (93), Expect = 0.007
Identities = 46/155 (29%), Positives = 70/155 (45%), Gaps = 14/155 (9%)
Query: 648 QRTRDALQ--RSVQLAIEITTNSQEAA-----AKHEAQRLEQEARGRLERQKILDQSEAE 700
Q R+A Q R V+ A + +++E A A+ A++L +EA R+ +Q+
Sbjct: 2236 QAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALR 2295
Query: 701 KARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQAL----AIETE 756
+ + E+E E T KA+ E R++ E + Q L + L A TE
Sbjct: 2296 QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATE 2355
Query: 757 AELQRVQKVRELELVYARAQLELEVSKAQQLAEVE 791
A QR Q E EL R Q+E E+SK + E E
Sbjct: 2356 AARQRSQV--EEELFSVRVQME-ELSKLKARIEAE 2387
Score = 39.7 bits (91), Expect = 0.013
Identities = 43/179 (24%), Positives = 84/179 (46%), Gaps = 20/179 (11%)
Query: 641 QSVEPVDQRTRDALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEA 699
+++E QR + + +L + + S+ +A A+ +AQR ++A E+ + +
Sbjct: 2503 RTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQ 2562
Query: 700 EKARK-ELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAE 758
EK + LE++ ++ +A AE E +++ E +LQ K + + ++ E
Sbjct: 2563 EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSE-EMQTVQQEQL 2621
Query: 759 LQRVQKV-------------RELELVYARAQLEL----EVSKAQQLAEVEVKKFKQMTE 800
LQ Q + RE + +A+LE EV+KAQQL E + ++ +QM +
Sbjct: 2622 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQ 2680
Score = 38.1 bits (87), Expect = 0.037
Identities = 43/180 (23%), Positives = 87/180 (48%), Gaps = 23/180 (12%)
Query: 662 IEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGT 721
+E + + A + E+ A+ + E ++ +++E E R +L EAL + +++
Sbjct: 1729 LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEV 1788
Query: 722 AKAEAESRAEAARIEGEGS-VLQAKLKAQALAI-ETEAELQRVQKVREL----------- 768
A+ ++ ++AEA + + E + + KA+ A+ + E Q ++K R+L
Sbjct: 1789 AQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAA 1848
Query: 769 --ELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAIGPSTIR-----DLAVAGPEMQVKL 821
EL+ RA+ E + + +QL E E+ + ++ EA + R +LA EM+V L
Sbjct: 1849 EQELIRLRAETE-QGEQQRQLLEEELARLQR--EAAAATQKRQELEAELAKVRAEMEVLL 1905
Score = 35.8 bits (81), Expect = 0.18
Identities = 26/120 (21%), Positives = 56/120 (46%), Gaps = 4/120 (3%)
Query: 683 EARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVL 742
E R+E ++ L + + + R+ L E+EA A A+A+++AE E + +
Sbjct: 1476 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1535
Query: 743 QAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAI 802
+ ++ + A++ + + + +Q+ EL R E E+ + AE + ++ E I
Sbjct: 1536 EEVVRREEAAVDAQQQKRSIQE----ELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEI 1591
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 46.6 bits (109), Expect = 1e-04
Identities = 43/152 (28%), Positives = 76/152 (50%), Gaps = 13/152 (8%)
Query: 648 QRTRDALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKEL 706
Q+ LQ+++Q + + EA A A +EAR + ER EA ++R+++
Sbjct: 2037 QQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER-------EAAQSRRQV 2089
Query: 707 LELEALSMAVESTGTAKAEAESRAEAARIEGEGSV---LQAKLKAQALAIETEAELQRVQ 763
E E L + E A+A+A++ AE R E E QA+ A +AE+++ +
Sbjct: 2090 EEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHK 2149
Query: 764 KVRELELVYARAQLELEVSKAQ-QLAEVEVKK 794
K E + + +AQ+E E++ + QL E + +K
Sbjct: 2150 KFAE-QTLRQKAQVEQELTTLRLQLEETDHQK 2180
Score = 45.4 bits (106), Expect = 2e-04
Identities = 41/154 (26%), Positives = 65/154 (42%), Gaps = 28/154 (18%)
Query: 669 QEAAAKHEAQRLEQEA------RGRLERQKILDQSEAEKARKELLELEALSMAVESTGTA 722
Q++ A+ EA++ ++EA RG+ E Q + + AE+ ELE E T
Sbjct: 1632 QKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQ------ELEKQRQLAEGTAQQ 1685
Query: 723 KAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEV- 781
+ AE R E E Q +L + LA QK +ELE A+ + E+EV
Sbjct: 1686 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL 1745
Query: 782 ---------------SKAQQLAEVEVKKFKQMTE 800
K++Q E E +F+++ E
Sbjct: 1746 LASKARAEEESRSTSEKSKQRLEAEAGRFRELAE 1779
Score = 45.1 bits (105), Expect = 3e-04
Identities = 50/159 (31%), Positives = 75/159 (47%), Gaps = 8/159 (5%)
Query: 648 QRTRDALQRS-VQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQ----SEAEKA 702
+ T A QRS V+ + E +K +A R+E E R + R K Q EAEK
Sbjct: 2193 EATEAARQRSQVEEELFSVRVQMEELSKLKA-RIEAENRALILRDKDNTQRFLQEEAEKM 2251
Query: 703 RKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRV 762
++ E LS+A + + AE R E +L+ K++A A +AE + +
Sbjct: 2252 KQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAE-KMLKEKMQAVQEATRLKAEAELL 2310
Query: 763 QKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEA 801
Q+ +EL AR E + AQQLAE E + F++ EA
Sbjct: 2311 QQQKELAQEQARRLQEDKEQMAQQLAE-ETQGFQRTLEA 2348
Score = 44.3 bits (103), Expect = 5e-04
Identities = 49/189 (25%), Positives = 85/189 (44%), Gaps = 33/189 (17%)
Query: 644 EPVDQRTRDALQRSVQLAIEITTNSQEA--AAKHEAQRLEQEARGRLERQKILDQSE--- 698
E + + R A + + +L ++ SQ A A R++ EA E+Q+ L E
Sbjct: 1461 EEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELR 1520
Query: 699 --AEKARKELLELEA-----LSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQAL 751
AE+A + L + E + +A+E T AEAE +++ A + + L+ L+ + +
Sbjct: 1521 LQAEEAERRLRQAEVERARQVQVALE-TAQRSAEAELQSKRASFAEKTAQLERSLQEEHV 1579
Query: 752 AI-------------ETEAELQRVQKVRELELVYARAQLEL-------EVSKAQQLAEVE 791
A+ + EAE R + RELE +A L EV++ + LA+ E
Sbjct: 1580 AVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAE 1639
Query: 792 VKKFKQMTE 800
+K K+ E
Sbjct: 1640 AEKQKEEAE 1648
Score = 43.5 bits (101), Expect = 9e-04
Identities = 42/156 (26%), Positives = 76/156 (48%), Gaps = 15/156 (9%)
Query: 647 DQRTRDALQR-SVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKE 705
++R R+A +R LA E Q AA E +RL+ + E +++ +++E E AR+
Sbjct: 1958 ERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVE---EARRLRERAEQESARQL 2014
Query: 706 LLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKL-KAQALAIETEAELQRVQK 764
L EA + +AE +A A ++ + LQ L + Q++ + E + ++
Sbjct: 2015 QLAQEA--------AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARR 2066
Query: 765 VRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTE 800
E E AR Q E E +++++ E E ++ KQ E
Sbjct: 2067 AAE-EAEEARVQAEREAAQSRRQVE-EAERLKQSAE 2100
Score = 43.5 bits (101), Expect = 9e-04
Identities = 48/170 (28%), Positives = 81/170 (47%), Gaps = 19/170 (11%)
Query: 641 QSVEPVDQRTR-----DALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILD 695
+ ++ V + TR + LQ+ +LA E QE + AQ+L +E +G Q+ L
Sbjct: 2292 EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDK-EQMAQQLAEETQGF---QRTL- 2346
Query: 696 QSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIET 755
EAE+ R+ + EA + + ++A+A + +A R + + KL LA +
Sbjct: 2347 --EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQE 2404
Query: 756 EA------ELQRVQKVRELE-LVYARAQLELEVSKAQQLAEVEVKKFKQM 798
+ E+QR Q + E L A A+LE E K QQ A++ K ++M
Sbjct: 2405 KVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM 2454
Score = 41.2 bits (95), Expect = 0.004
Identities = 41/140 (29%), Positives = 67/140 (47%), Gaps = 11/140 (7%)
Query: 653 ALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEA 711
AL++ QLA ++Q +A A+ EA+ L+Q + + R++ ++ R EL+
Sbjct: 1346 ALEKQRQLA---EAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQ 1402
Query: 712 LSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELV 771
L + E+ AKA AE +R+ E + +L+ +A E QR EL+ +
Sbjct: 1403 LRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA------TERQRGGAEGELQAL 1456
Query: 772 YARAQLELEVSKAQQLAEVE 791
ARA+ E E K Q E E
Sbjct: 1457 RARAE-EAEAQKRQAQEEAE 1475
Score = 41.2 bits (95), Expect = 0.004
Identities = 47/169 (27%), Positives = 76/169 (44%), Gaps = 13/169 (7%)
Query: 669 QEAAAKHEAQ------RLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTA 722
+E AA+H+A +L + + LERQK L + + R+ E+ AL + E
Sbjct: 1859 EEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAG 1918
Query: 723 KAEAESRAEAARIEGEGSVL---QAKLKAQALAIETEAELQRVQKVRELELVYARAQLEL 779
KAE E R E ++ QA+L+A A + AE +R ++ E E V E
Sbjct: 1919 KAELELELGRIRSNAEDTLRSKEQAELEA-ARQRQLAAEEERRRREAE-ERVQKSLAAEE 1976
Query: 780 EVSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLK 828
E ++ ++ A EV++ K E +R+ A Q++L Q K
Sbjct: 1977 EAARQRKAALEEVERLKAKVEE--ARRLRERAEQESARQLQLAQEAAQK 2023
Score = 40.4 bits (93), Expect = 0.007
Identities = 46/155 (29%), Positives = 70/155 (45%), Gaps = 14/155 (9%)
Query: 648 QRTRDALQ--RSVQLAIEITTNSQEAA-----AKHEAQRLEQEARGRLERQKILDQSEAE 700
Q R+A Q R V+ A + +++E A A+ A++L +EA R+ +Q+
Sbjct: 2077 QAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALR 2136
Query: 701 KARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQAL----AIETE 756
+ + E+E E T KA+ E R++ E + Q L + L A TE
Sbjct: 2137 QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATE 2196
Query: 757 AELQRVQKVRELELVYARAQLELEVSKAQQLAEVE 791
A QR Q E EL R Q+E E+SK + E E
Sbjct: 2197 AARQRSQV--EEELFSVRVQME-ELSKLKARIEAE 2228
Score = 39.7 bits (91), Expect = 0.013
Identities = 43/179 (24%), Positives = 84/179 (46%), Gaps = 20/179 (11%)
Query: 641 QSVEPVDQRTRDALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEA 699
+++E QR + + +L + + S+ +A A+ +AQR ++A E+ + +
Sbjct: 2344 RTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQ 2403
Query: 700 EKARK-ELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAE 758
EK + LE++ ++ +A AE E +++ E +LQ K + + ++ E
Sbjct: 2404 EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSE-EMQTVQQEQL 2462
Query: 759 LQRVQKV-------------RELELVYARAQLEL----EVSKAQQLAEVEVKKFKQMTE 800
LQ Q + RE + +A+LE EV+KAQQL E + ++ +QM +
Sbjct: 2463 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQ 2521
Score = 38.1 bits (87), Expect = 0.037
Identities = 43/180 (23%), Positives = 87/180 (48%), Gaps = 23/180 (12%)
Query: 662 IEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGT 721
+E + + A + E+ A+ + E ++ +++E E R +L EAL + +++
Sbjct: 1570 LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEV 1629
Query: 722 AKAEAESRAEAARIEGEGS-VLQAKLKAQALAI-ETEAELQRVQKVREL----------- 768
A+ ++ ++AEA + + E + + KA+ A+ + E Q ++K R+L
Sbjct: 1630 AQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAA 1689
Query: 769 --ELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAIGPSTIR-----DLAVAGPEMQVKL 821
EL+ RA+ E + + +QL E E+ + ++ EA + R +LA EM+V L
Sbjct: 1690 EQELIRLRAETE-QGEQQRQLLEEELARLQR--EAAAATQKRQELEAELAKVRAEMEVLL 1746
Score = 35.8 bits (81), Expect = 0.18
Identities = 26/120 (21%), Positives = 56/120 (46%), Gaps = 4/120 (3%)
Query: 683 EARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVL 742
E R+E ++ L + + + R+ L E+EA A A+A+++AE E + +
Sbjct: 1317 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1376
Query: 743 QAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAI 802
+ ++ + A++ + + + +Q+ EL R E E+ + AE + ++ E I
Sbjct: 1377 EEVVRREEAAVDAQQQKRSIQE----ELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEI 1432
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 46.6 bits (109), Expect = 1e-04
Identities = 43/152 (28%), Positives = 76/152 (50%), Gaps = 13/152 (8%)
Query: 648 QRTRDALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKEL 706
Q+ LQ+++Q + + EA A A +EAR + ER EA ++R+++
Sbjct: 2045 QQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER-------EAAQSRRQV 2097
Query: 707 LELEALSMAVESTGTAKAEAESRAEAARIEGEGSV---LQAKLKAQALAIETEAELQRVQ 763
E E L + E A+A+A++ AE R E E QA+ A +AE+++ +
Sbjct: 2098 EEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHK 2157
Query: 764 KVRELELVYARAQLELEVSKAQ-QLAEVEVKK 794
K E + + +AQ+E E++ + QL E + +K
Sbjct: 2158 KFAE-QTLRQKAQVEQELTTLRLQLEETDHQK 2188
Score = 45.4 bits (106), Expect = 2e-04
Identities = 41/154 (26%), Positives = 65/154 (42%), Gaps = 28/154 (18%)
Query: 669 QEAAAKHEAQRLEQEA------RGRLERQKILDQSEAEKARKELLELEALSMAVESTGTA 722
Q++ A+ EA++ ++EA RG+ E Q + + AE+ ELE E T
Sbjct: 1640 QKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQ------ELEKQRQLAEGTAQQ 1693
Query: 723 KAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEV- 781
+ AE R E E Q +L + LA QK +ELE A+ + E+EV
Sbjct: 1694 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL 1753
Query: 782 ---------------SKAQQLAEVEVKKFKQMTE 800
K++Q E E +F+++ E
Sbjct: 1754 LASKARAEEESRSTSEKSKQRLEAEAGRFRELAE 1787
Score = 45.1 bits (105), Expect = 3e-04
Identities = 50/159 (31%), Positives = 75/159 (47%), Gaps = 8/159 (5%)
Query: 648 QRTRDALQRS-VQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQ----SEAEKA 702
+ T A QRS V+ + E +K +A R+E E R + R K Q EAEK
Sbjct: 2201 EATEAARQRSQVEEELFSVRVQMEELSKLKA-RIEAENRALILRDKDNTQRFLQEEAEKM 2259
Query: 703 RKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRV 762
++ E LS+A + + AE R E +L+ K++A A +AE + +
Sbjct: 2260 KQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAE-KMLKEKMQAVQEATRLKAEAELL 2318
Query: 763 QKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEA 801
Q+ +EL AR E + AQQLAE E + F++ EA
Sbjct: 2319 QQQKELAQEQARRLQEDKEQMAQQLAE-ETQGFQRTLEA 2356
Score = 44.3 bits (103), Expect = 5e-04
Identities = 49/189 (25%), Positives = 85/189 (44%), Gaps = 33/189 (17%)
Query: 644 EPVDQRTRDALQRSVQLAIEITTNSQEA--AAKHEAQRLEQEARGRLERQKILDQSE--- 698
E + + R A + + +L ++ SQ A A R++ EA E+Q+ L E
Sbjct: 1469 EEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELR 1528
Query: 699 --AEKARKELLELEA-----LSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQAL 751
AE+A + L + E + +A+E T AEAE +++ A + + L+ L+ + +
Sbjct: 1529 LQAEEAERRLRQAEVERARQVQVALE-TAQRSAEAELQSKRASFAEKTAQLERSLQEEHV 1587
Query: 752 AI-------------ETEAELQRVQKVRELELVYARAQLEL-------EVSKAQQLAEVE 791
A+ + EAE R + RELE +A L EV++ + LA+ E
Sbjct: 1588 AVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAE 1647
Query: 792 VKKFKQMTE 800
+K K+ E
Sbjct: 1648 AEKQKEEAE 1656
Score = 43.5 bits (101), Expect = 9e-04
Identities = 42/156 (26%), Positives = 76/156 (48%), Gaps = 15/156 (9%)
Query: 647 DQRTRDALQR-SVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKE 705
++R R+A +R LA E Q AA E +RL+ + E +++ +++E E AR+
Sbjct: 1966 ERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVE---EARRLRERAEQESARQL 2022
Query: 706 LLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKL-KAQALAIETEAELQRVQK 764
L EA + +AE +A A ++ + LQ L + Q++ + E + ++
Sbjct: 2023 QLAQEA--------AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARR 2074
Query: 765 VRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTE 800
E E AR Q E E +++++ E E ++ KQ E
Sbjct: 2075 AAE-EAEEARVQAEREAAQSRRQVE-EAERLKQSAE 2108
Score = 43.5 bits (101), Expect = 9e-04
Identities = 48/170 (28%), Positives = 81/170 (47%), Gaps = 19/170 (11%)
Query: 641 QSVEPVDQRTR-----DALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILD 695
+ ++ V + TR + LQ+ +LA E QE + AQ+L +E +G Q+ L
Sbjct: 2300 EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDK-EQMAQQLAEETQGF---QRTL- 2354
Query: 696 QSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIET 755
EAE+ R+ + EA + + ++A+A + +A R + + KL LA +
Sbjct: 2355 --EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQE 2412
Query: 756 EA------ELQRVQKVRELE-LVYARAQLELEVSKAQQLAEVEVKKFKQM 798
+ E+QR Q + E L A A+LE E K QQ A++ K ++M
Sbjct: 2413 KVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM 2462
Score = 41.2 bits (95), Expect = 0.004
Identities = 41/140 (29%), Positives = 67/140 (47%), Gaps = 11/140 (7%)
Query: 653 ALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEA 711
AL++ QLA ++Q +A A+ EA+ L+Q + + R++ ++ R EL+
Sbjct: 1354 ALEKQRQLA---EAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQ 1410
Query: 712 LSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELV 771
L + E+ AKA AE +R+ E + +L+ +A E QR EL+ +
Sbjct: 1411 LRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA------TERQRGGAEGELQAL 1464
Query: 772 YARAQLELEVSKAQQLAEVE 791
ARA+ E E K Q E E
Sbjct: 1465 RARAE-EAEAQKRQAQEEAE 1483
Score = 41.2 bits (95), Expect = 0.004
Identities = 47/169 (27%), Positives = 76/169 (44%), Gaps = 13/169 (7%)
Query: 669 QEAAAKHEAQ------RLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTA 722
+E AA+H+A +L + + LERQK L + + R+ E+ AL + E
Sbjct: 1867 EEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAG 1926
Query: 723 KAEAESRAEAARIEGEGSVL---QAKLKAQALAIETEAELQRVQKVRELELVYARAQLEL 779
KAE E R E ++ QA+L+A A + AE +R ++ E E V E
Sbjct: 1927 KAELELELGRIRSNAEDTLRSKEQAELEA-ARQRQLAAEEERRRREAE-ERVQKSLAAEE 1984
Query: 780 EVSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLK 828
E ++ ++ A EV++ K E +R+ A Q++L Q K
Sbjct: 1985 EAARQRKAALEEVERLKAKVEE--ARRLRERAEQESARQLQLAQEAAQK 2031
Score = 40.4 bits (93), Expect = 0.007
Identities = 46/155 (29%), Positives = 70/155 (45%), Gaps = 14/155 (9%)
Query: 648 QRTRDALQ--RSVQLAIEITTNSQEAA-----AKHEAQRLEQEARGRLERQKILDQSEAE 700
Q R+A Q R V+ A + +++E A A+ A++L +EA R+ +Q+
Sbjct: 2085 QAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALR 2144
Query: 701 KARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQAL----AIETE 756
+ + E+E E T KA+ E R++ E + Q L + L A TE
Sbjct: 2145 QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATE 2204
Query: 757 AELQRVQKVRELELVYARAQLELEVSKAQQLAEVE 791
A QR Q E EL R Q+E E+SK + E E
Sbjct: 2205 AARQRSQV--EEELFSVRVQME-ELSKLKARIEAE 2236
Score = 39.7 bits (91), Expect = 0.013
Identities = 43/179 (24%), Positives = 84/179 (46%), Gaps = 20/179 (11%)
Query: 641 QSVEPVDQRTRDALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEA 699
+++E QR + + +L + + S+ +A A+ +AQR ++A E+ + +
Sbjct: 2352 RTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQ 2411
Query: 700 EKARK-ELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAE 758
EK + LE++ ++ +A AE E +++ E +LQ K + + ++ E
Sbjct: 2412 EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSE-EMQTVQQEQL 2470
Query: 759 LQRVQKV-------------RELELVYARAQLEL----EVSKAQQLAEVEVKKFKQMTE 800
LQ Q + RE + +A+LE EV+KAQQL E + ++ +QM +
Sbjct: 2471 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQ 2529
Score = 38.1 bits (87), Expect = 0.037
Identities = 43/180 (23%), Positives = 87/180 (48%), Gaps = 23/180 (12%)
Query: 662 IEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGT 721
+E + + A + E+ A+ + E ++ +++E E R +L EAL + +++
Sbjct: 1578 LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEV 1637
Query: 722 AKAEAESRAEAARIEGEGS-VLQAKLKAQALAI-ETEAELQRVQKVREL----------- 768
A+ ++ ++AEA + + E + + KA+ A+ + E Q ++K R+L
Sbjct: 1638 AQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAA 1697
Query: 769 --ELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAIGPSTIR-----DLAVAGPEMQVKL 821
EL+ RA+ E + + +QL E E+ + ++ EA + R +LA EM+V L
Sbjct: 1698 EQELIRLRAETE-QGEQQRQLLEEELARLQR--EAAAATQKRQELEAELAKVRAEMEVLL 1754
Score = 35.8 bits (81), Expect = 0.18
Identities = 26/120 (21%), Positives = 56/120 (46%), Gaps = 4/120 (3%)
Query: 683 EARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVL 742
E R+E ++ L + + + R+ L E+EA A A+A+++AE E + +
Sbjct: 1325 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1384
Query: 743 QAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAI 802
+ ++ + A++ + + + +Q+ EL R E E+ + AE + ++ E I
Sbjct: 1385 EEVVRREEAAVDAQQQKRSIQE----ELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEI 1440
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 46.6 bits (109), Expect = 1e-04
Identities = 43/152 (28%), Positives = 76/152 (50%), Gaps = 13/152 (8%)
Query: 648 QRTRDALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKEL 706
Q+ LQ+++Q + + EA A A +EAR + ER EA ++R+++
Sbjct: 2086 QQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER-------EAAQSRRQV 2138
Query: 707 LELEALSMAVESTGTAKAEAESRAEAARIEGEGSV---LQAKLKAQALAIETEAELQRVQ 763
E E L + E A+A+A++ AE R E E QA+ A +AE+++ +
Sbjct: 2139 EEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHK 2198
Query: 764 KVRELELVYARAQLELEVSKAQ-QLAEVEVKK 794
K E + + +AQ+E E++ + QL E + +K
Sbjct: 2199 KFAE-QTLRQKAQVEQELTTLRLQLEETDHQK 2229
Score = 45.4 bits (106), Expect = 2e-04
Identities = 41/154 (26%), Positives = 65/154 (42%), Gaps = 28/154 (18%)
Query: 669 QEAAAKHEAQRLEQEA------RGRLERQKILDQSEAEKARKELLELEALSMAVESTGTA 722
Q++ A+ EA++ ++EA RG+ E Q + + AE+ ELE E T
Sbjct: 1681 QKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQ------ELEKQRQLAEGTAQQ 1734
Query: 723 KAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEV- 781
+ AE R E E Q +L + LA QK +ELE A+ + E+EV
Sbjct: 1735 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL 1794
Query: 782 ---------------SKAQQLAEVEVKKFKQMTE 800
K++Q E E +F+++ E
Sbjct: 1795 LASKARAEEESRSTSEKSKQRLEAEAGRFRELAE 1828
Score = 45.1 bits (105), Expect = 3e-04
Identities = 50/159 (31%), Positives = 75/159 (47%), Gaps = 8/159 (5%)
Query: 648 QRTRDALQRS-VQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQ----SEAEKA 702
+ T A QRS V+ + E +K +A R+E E R + R K Q EAEK
Sbjct: 2242 EATEAARQRSQVEEELFSVRVQMEELSKLKA-RIEAENRALILRDKDNTQRFLQEEAEKM 2300
Query: 703 RKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRV 762
++ E LS+A + + AE R E +L+ K++A A +AE + +
Sbjct: 2301 KQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAE-KMLKEKMQAVQEATRLKAEAELL 2359
Query: 763 QKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEA 801
Q+ +EL AR E + AQQLAE E + F++ EA
Sbjct: 2360 QQQKELAQEQARRLQEDKEQMAQQLAE-ETQGFQRTLEA 2397
Score = 44.3 bits (103), Expect = 5e-04
Identities = 49/189 (25%), Positives = 85/189 (44%), Gaps = 33/189 (17%)
Query: 644 EPVDQRTRDALQRSVQLAIEITTNSQEA--AAKHEAQRLEQEARGRLERQKILDQSE--- 698
E + + R A + + +L ++ SQ A A R++ EA E+Q+ L E
Sbjct: 1510 EEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELR 1569
Query: 699 --AEKARKELLELEA-----LSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQAL 751
AE+A + L + E + +A+E T AEAE +++ A + + L+ L+ + +
Sbjct: 1570 LQAEEAERRLRQAEVERARQVQVALE-TAQRSAEAELQSKRASFAEKTAQLERSLQEEHV 1628
Query: 752 AI-------------ETEAELQRVQKVRELELVYARAQLEL-------EVSKAQQLAEVE 791
A+ + EAE R + RELE +A L EV++ + LA+ E
Sbjct: 1629 AVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAE 1688
Query: 792 VKKFKQMTE 800
+K K+ E
Sbjct: 1689 AEKQKEEAE 1697
Score = 43.5 bits (101), Expect = 9e-04
Identities = 42/156 (26%), Positives = 76/156 (48%), Gaps = 15/156 (9%)
Query: 647 DQRTRDALQR-SVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKE 705
++R R+A +R LA E Q AA E +RL+ + E +++ +++E E AR+
Sbjct: 2007 ERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVE---EARRLRERAEQESARQL 2063
Query: 706 LLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKL-KAQALAIETEAELQRVQK 764
L EA + +AE +A A ++ + LQ L + Q++ + E + ++
Sbjct: 2064 QLAQEA--------AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARR 2115
Query: 765 VRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTE 800
E E AR Q E E +++++ E E ++ KQ E
Sbjct: 2116 AAE-EAEEARVQAEREAAQSRRQVE-EAERLKQSAE 2149
Score = 43.5 bits (101), Expect = 9e-04
Identities = 48/170 (28%), Positives = 81/170 (47%), Gaps = 19/170 (11%)
Query: 641 QSVEPVDQRTR-----DALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILD 695
+ ++ V + TR + LQ+ +LA E QE + AQ+L +E +G Q+ L
Sbjct: 2341 EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDK-EQMAQQLAEETQGF---QRTL- 2395
Query: 696 QSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIET 755
EAE+ R+ + EA + + ++A+A + +A R + + KL LA +
Sbjct: 2396 --EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQE 2453
Query: 756 EA------ELQRVQKVRELE-LVYARAQLELEVSKAQQLAEVEVKKFKQM 798
+ E+QR Q + E L A A+LE E K QQ A++ K ++M
Sbjct: 2454 KVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM 2503
Score = 41.2 bits (95), Expect = 0.004
Identities = 41/140 (29%), Positives = 67/140 (47%), Gaps = 11/140 (7%)
Query: 653 ALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEA 711
AL++ QLA ++Q +A A+ EA+ L+Q + + R++ ++ R EL+
Sbjct: 1395 ALEKQRQLA---EAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQ 1451
Query: 712 LSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELV 771
L + E+ AKA AE +R+ E + +L+ +A E QR EL+ +
Sbjct: 1452 LRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA------TERQRGGAEGELQAL 1505
Query: 772 YARAQLELEVSKAQQLAEVE 791
ARA+ E E K Q E E
Sbjct: 1506 RARAE-EAEAQKRQAQEEAE 1524
Score = 41.2 bits (95), Expect = 0.004
Identities = 47/169 (27%), Positives = 76/169 (44%), Gaps = 13/169 (7%)
Query: 669 QEAAAKHEAQ------RLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTA 722
+E AA+H+A +L + + LERQK L + + R+ E+ AL + E
Sbjct: 1908 EEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAG 1967
Query: 723 KAEAESRAEAARIEGEGSVL---QAKLKAQALAIETEAELQRVQKVRELELVYARAQLEL 779
KAE E R E ++ QA+L+A A + AE +R ++ E E V E
Sbjct: 1968 KAELELELGRIRSNAEDTLRSKEQAELEA-ARQRQLAAEEERRRREAE-ERVQKSLAAEE 2025
Query: 780 EVSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLK 828
E ++ ++ A EV++ K E +R+ A Q++L Q K
Sbjct: 2026 EAARQRKAALEEVERLKAKVEE--ARRLRERAEQESARQLQLAQEAAQK 2072
Score = 40.4 bits (93), Expect = 0.007
Identities = 46/155 (29%), Positives = 70/155 (45%), Gaps = 14/155 (9%)
Query: 648 QRTRDALQ--RSVQLAIEITTNSQEAA-----AKHEAQRLEQEARGRLERQKILDQSEAE 700
Q R+A Q R V+ A + +++E A A+ A++L +EA R+ +Q+
Sbjct: 2126 QAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALR 2185
Query: 701 KARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQAL----AIETE 756
+ + E+E E T KA+ E R++ E + Q L + L A TE
Sbjct: 2186 QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATE 2245
Query: 757 AELQRVQKVRELELVYARAQLELEVSKAQQLAEVE 791
A QR Q E EL R Q+E E+SK + E E
Sbjct: 2246 AARQRSQV--EEELFSVRVQME-ELSKLKARIEAE 2277
Score = 39.7 bits (91), Expect = 0.013
Identities = 43/179 (24%), Positives = 84/179 (46%), Gaps = 20/179 (11%)
Query: 641 QSVEPVDQRTRDALQRSVQLAIEITTNSQ-EAAAKHEAQRLEQEARGRLERQKILDQSEA 699
+++E QR + + +L + + S+ +A A+ +AQR ++A E+ + +
Sbjct: 2393 RTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQ 2452
Query: 700 EKARK-ELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAE 758
EK + LE++ ++ +A AE E +++ E +LQ K + + ++ E
Sbjct: 2453 EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSE-EMQTVQQEQL 2511
Query: 759 LQRVQKV-------------RELELVYARAQLEL----EVSKAQQLAEVEVKKFKQMTE 800
LQ Q + RE + +A+LE EV+KAQQL E + ++ +QM +
Sbjct: 2512 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQ 2570
Score = 38.1 bits (87), Expect = 0.037
Identities = 43/180 (23%), Positives = 87/180 (48%), Gaps = 23/180 (12%)
Query: 662 IEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGT 721
+E + + A + E+ A+ + E ++ +++E E R +L EAL + +++
Sbjct: 1619 LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEV 1678
Query: 722 AKAEAESRAEAARIEGEGS-VLQAKLKAQALAI-ETEAELQRVQKVREL----------- 768
A+ ++ ++AEA + + E + + KA+ A+ + E Q ++K R+L
Sbjct: 1679 AQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAA 1738
Query: 769 --ELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAIGPSTIR-----DLAVAGPEMQVKL 821
EL+ RA+ E + + +QL E E+ + ++ EA + R +LA EM+V L
Sbjct: 1739 EQELIRLRAETE-QGEQQRQLLEEELARLQR--EAAAATQKRQELEAELAKVRAEMEVLL 1795
Score = 35.8 bits (81), Expect = 0.18
Identities = 26/120 (21%), Positives = 56/120 (46%), Gaps = 4/120 (3%)
Query: 683 EARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVL 742
E R+E ++ L + + + R+ L E+EA A A+A+++AE E + +
Sbjct: 1366 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1425
Query: 743 QAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAI 802
+ ++ + A++ + + + +Q+ EL R E E+ + AE + ++ E I
Sbjct: 1426 EEVVRREEAAVDAQQQKRSIQE----ELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEI 1481
>gi|94538362 flotillin 2 [Homo sapiens]
Length = 428
Score = 45.8 bits (107), Expect = 2e-04
Identities = 40/125 (32%), Positives = 69/125 (55%), Gaps = 14/125 (11%)
Query: 652 DALQRSVQLAIE----ITTNSQEAA-----AKHEAQRLEQEARGRLERQKILDQSEAEKA 702
+ +QR Q+A+E + T+ + A A+ EA R++Q A G +Q +L Q+EAEK
Sbjct: 260 EVVQRKKQIAVEAQEILRTDKELIATVRRPAEAEAHRIQQIAEGEKVKQVLLAQAEAEKI 319
Query: 703 RKELLELEALSMAVESTGTAKAE-AESRAEAARIEGEGSVLQAKLKA-QALAIETEAELQ 760
RK EA + +E+ G A+AE + +AEA + G+ + + L+A +A + A L
Sbjct: 320 RK---IGEAEAAVIEAMGKAEAERMKLKAEAYQKYGDAAKMALVLEALPQIAAKIAAPLT 376
Query: 761 RVQKV 765
+V ++
Sbjct: 377 KVDEI 381
Score = 33.9 bits (76), Expect = 0.69
Identities = 36/147 (24%), Positives = 62/147 (42%), Gaps = 10/147 (6%)
Query: 647 DQRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKEL 706
D + LQ+S + E+ + EA +E Q ++ + R E +I ++ E
Sbjct: 214 DSKRAFELQKSA-FSEEVNIKTAEAQLAYELQGAREQQKIRQEEIEIEVVQRKKQIAVEA 272
Query: 707 LELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVR 766
E+ + +T AEAE+ EGE K+K LA +AE ++++K+
Sbjct: 273 QEILRTDKELIATVRRPAEAEAHRIQQIAEGE------KVKQVLLA---QAEAEKIRKIG 323
Query: 767 ELELVYARAQLELEVSKAQQLAEVEVK 793
E E A + E + + AE K
Sbjct: 324 EAEAAVIEAMGKAEAERMKLKAEAYQK 350
Score = 32.3 bits (72), Expect = 2.0
Identities = 34/138 (24%), Positives = 55/138 (39%), Gaps = 32/138 (23%)
Query: 668 SQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALS----MAVESTGTAK 723
S+E K +L E +G E+QKI R+E +E+E + +AVE+ +
Sbjct: 227 SEEVNIKTAEAQLAYELQGAREQQKI---------RQEEIEIEVVQRKKQIAVEAQEILR 277
Query: 724 AEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSK 783
+ E A R EAE R+Q++ E E V + E K
Sbjct: 278 TDKELIATVRR-------------------PAEAEAHRIQQIAEGEKVKQVLLAQAEAEK 318
Query: 784 AQQLAEVEVKKFKQMTEA 801
+++ E E + M +A
Sbjct: 319 IRKIGEAEAAVIEAMGKA 336
>gi|191252785 centrobin, centrosomal BRCA2 interacting protein
isoform alpha [Homo sapiens]
Length = 903
Score = 45.8 bits (107), Expect = 2e-04
Identities = 40/138 (28%), Positives = 72/138 (52%), Gaps = 12/138 (8%)
Query: 665 TTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKA 724
T QE K Q L++E++ +LER+K Q EA+ A + +L A+ + +
Sbjct: 361 TWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQL-----ALVQSEVRRL 415
Query: 725 EAE---SRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEV 781
E E +R E ++ E S++QA+ ++Q + +E+E +Q Q+V E A+AQ E +
Sbjct: 416 EGELDTARRERDALQLEMSLVQARYESQRIQLESELAVQLEQRVTER---LAQAQ-ESSL 471
Query: 782 SKAQQLAEVEVKKFKQMT 799
+A L E K+ + ++
Sbjct: 472 RQAASLREHHRKQLQDLS 489
>gi|80861396 centrobin, centrosomal BRCA2 interacting protein
isoform beta [Homo sapiens]
Length = 925
Score = 45.8 bits (107), Expect = 2e-04
Identities = 40/138 (28%), Positives = 72/138 (52%), Gaps = 12/138 (8%)
Query: 665 TTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKA 724
T QE K Q L++E++ +LER+K Q EA+ A + +L A+ + +
Sbjct: 361 TWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQL-----ALVQSEVRRL 415
Query: 725 EAE---SRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEV 781
E E +R E ++ E S++QA+ ++Q + +E+E +Q Q+V E A+AQ E +
Sbjct: 416 EGELDTARRERDALQLEMSLVQARYESQRIQLESELAVQLEQRVTER---LAQAQ-ESSL 471
Query: 782 SKAQQLAEVEVKKFKQMT 799
+A L E K+ + ++
Sbjct: 472 RQAASLREHHRKQLQDLS 489
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 45.1 bits (105), Expect = 3e-04
Identities = 68/284 (23%), Positives = 116/284 (40%), Gaps = 36/284 (12%)
Query: 607 ETSEAKGPDGMALPRPRDQAVFPQNGLVVSSVDVQSVEPVDQRTRDALQRSVQLAIEITT 666
E EA +G A P D P+ V + P ++ SV+ A+E
Sbjct: 1872 EDVEAPEAEGEAQPESEDVET-PEAEWEVQPESEGAEAPEAEKEAQPETESVE-ALETEG 1929
Query: 667 NSQ---EAAAKHEAQRLEQEARGRLERQ-KILDQSEAEK-ARKELLELEALSMAVESTGT 721
+ E A EA+ QEA G+ + + ++++ EAE+ A+ E ++EAL + VE T
Sbjct: 1930 EDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVE---T 1986
Query: 722 AKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEV 781
+AE E++ E+ +E A E E E+Q ++ + E AQ + E
Sbjct: 1987 QEAEGEAQPESEDVE---------------APEAEGEMQEAEEEAQPESDGVEAQPKSEG 2031
Query: 782 SKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLKSTLITDGSTPINL 841
+AQ EV+ Q TE G + V PE + + ++ G + + +
Sbjct: 2032 EEAQ-----EVEGETQKTE--GDAQPESDGVEAPEAEEEAQEAEGE----VQEAEGEAHP 2080
Query: 842 FNTAFGLLGMGPEGQPLGRRVASGPSPGEGISPQSAQAPQAPGD 885
+ E QP V + + GE + +AP+ G+
Sbjct: 2081 ESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGE 2124
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 43.9 bits (102), Expect = 7e-04
Identities = 54/211 (25%), Positives = 93/211 (44%), Gaps = 24/211 (11%)
Query: 642 SVEPVDQRTRDALQRSVQLAIEITTNSQEAAAKHEAQR--LEQEARGR------LERQKI 693
S+E +R DAL+ + E+ ++ +H+ +R LE+E GR L++
Sbjct: 717 SLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGE 776
Query: 694 LDQSEAEKARKELLELEALSMAVES--TGTAKAEAESRAEAARIEGEGSVLQAKLKAQAL 751
Q+E E R+EL E A ES K A R + E + A + Q +
Sbjct: 777 AHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLM 836
Query: 752 AIETEAE--LQRVQKVRE--------LELVYARAQ---LELEVSKAQQLAEVEVKKFKQM 798
++ E E Q +Q+ +E EL +R Q EL + A+ L +V+ K+ +
Sbjct: 837 TLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQ 896
Query: 799 TEAIGPSTIRDLAVAGPEMQVKLLQSLGLKS 829
A ST+++ +A +V L++L K+
Sbjct: 897 KLADDLSTLQE-KMAATSKEVARLETLVRKA 926
Score = 38.1 bits (87), Expect = 0.037
Identities = 39/165 (23%), Positives = 73/165 (44%), Gaps = 19/165 (11%)
Query: 648 QRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELL 707
QR + L R V+ +++ + +AQ E E + R E+QK ++ + + +L
Sbjct: 642 QREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQ 701
Query: 708 E-LEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIE------------ 754
E L+AL +++ T + E + RA A E + + + K + ++L +
Sbjct: 702 EQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEER 761
Query: 755 -----TEAELQRVQKVRELELVYARAQLELEVSKAQQLAEVEVKK 794
EA LQ++ + + E R +L E AQ AE E ++
Sbjct: 762 AGRKGLEARLQQLGEAHQAETEVLRREL-AEAMAAQHTAESECEQ 805
Score = 36.6 bits (83), Expect = 0.11
Identities = 46/134 (34%), Positives = 62/134 (46%), Gaps = 15/134 (11%)
Query: 672 AAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAE 731
AA E+Q +QE RG+ ER+ E +A+ +L AL A A+AE E R +
Sbjct: 986 AALMESQGQQQEERGQQEREVARLTQERGRAQADL----ALEKA------ARAELEMRLQ 1035
Query: 732 AARIEG--EGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSKAQQLAE 789
A E E + LQ L A AL E E + Q + K+R LE + EL +QL E
Sbjct: 1036 NALNEQRVEFATLQEAL-AHALT-EKEGKDQELAKLRGLEAAQIKELEELR-QTVKQLKE 1092
Query: 790 VEVKKFKQMTEAIG 803
KK K+ G
Sbjct: 1093 QLAKKEKEHASGSG 1106
Score = 34.7 bits (78), Expect = 0.41
Identities = 53/222 (23%), Positives = 96/222 (43%), Gaps = 21/222 (9%)
Query: 668 SQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEA-LSMAVESTGTAKAEA 726
S++ A +A +++Q+ ++ Q Q EA++ + +L EL+A LS ++ K +
Sbjct: 1555 SKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQM 1614
Query: 727 E-SRAEAARIEGEGSVLQAKLKA----QALAIETEAELQRV-QKVRELELVYARAQLELE 780
E ++ + + LQ +L++ Q E AE +R+ ++++ L A+
Sbjct: 1615 EKAKTHYDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCR 1674
Query: 781 VSKAQ-QLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLKS-TLITDGSTP 838
AQ + E +V Q +G + A+ E Q K L + S L + TP
Sbjct: 1675 HLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTP 1734
Query: 839 INLFNTAFGLLGMGPEGQPLGRRVASGPSPGEGISPQSAQAP 880
+++ + P QP G V PGE SP S + P
Sbjct: 1735 LSITSKL-------PRTQPDGTSV-----PGEPASPISQRLP 1764
Score = 32.7 bits (73), Expect = 1.5
Identities = 45/188 (23%), Positives = 86/188 (45%), Gaps = 26/188 (13%)
Query: 640 VQSVEPVDQRTRDALQRSVQ--LAIEITTNSQ------EAAA---KHEAQRLEQEARGRL 688
+Q + Q + L+R + +A + T S+ E AA ++E + E+ G +
Sbjct: 771 LQQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAM 830
Query: 689 ERQKILD-QSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLK 747
+++++ + E EKAR+EL E + +ES S + +R + E + L A L
Sbjct: 831 FQEQLMTLKEECEKARQELQEAKEKVAGIES--------HSELQISRQQNELAELHANL- 881
Query: 748 AQALAIETEAELQRVQKVRELELVYAR-AQLELEVSKAQQLAEVEVKKFKQMTEAIGPST 806
A+AL E E++ + +L + + A EV++ + L V+K + E
Sbjct: 882 ARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETL----VRKAGEQQETASREL 937
Query: 807 IRDLAVAG 814
+++ A AG
Sbjct: 938 VKEPARAG 945
>gi|157042792 coiled-coil domain containing 64B [Homo sapiens]
Length = 508
Score = 43.9 bits (102), Expect = 7e-04
Identities = 50/189 (26%), Positives = 90/189 (47%), Gaps = 27/189 (14%)
Query: 661 AIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQ------------SEAEKARKEL-L 707
A+E+ + + A+ QR EQ+ GR ER + L + ++A + +EL
Sbjct: 118 AVELEGDVEALRAQLGEQRSEQQDSGR-ERARALSELSEQNLRLSQQLAQASQTEQELQR 176
Query: 708 ELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAK---LKAQALAIETEAEL--QRV 762
EL+AL ++ A AE +R E+ ++GE +LQ++ L+AQ + E E R+
Sbjct: 177 ELDALRGQCQAQALAGAELRTRLES--LQGENQMLQSRRQDLEAQIRGLREEVEKGEGRL 234
Query: 763 QKVRELELVYARAQLE--LEVSKAQQLAEVEVKKFKQMTEAIG----PSTIRDLAVAGPE 816
Q E L+ R + E LE+ +A+ A + +++ + S ++D V+
Sbjct: 235 QTTHEELLLLRRERREHSLELERARSEAGEALSALRRLQRRVSELEEESRLQDADVSAAS 294
Query: 817 MQVKLLQSL 825
+Q +L SL
Sbjct: 295 LQSELAHSL 303
>gi|93102364 SWAP-70 protein [Homo sapiens]
Length = 585
Score = 43.5 bits (101), Expect = 9e-04
Identities = 34/132 (25%), Positives = 64/132 (48%), Gaps = 18/132 (13%)
Query: 682 QEARGRLERQKILDQSEAEKARKELL--------ELEALSMAVESTGTAKAEAESRAEAA 733
++ R L ++++ +Q E E+ KEL ELEA+ +E + AE E +
Sbjct: 320 RQRRKELRKKQLAEQEELERQMKELQAANESKQQELEAVRKKLEEAASRAAEEEKKRLQT 379
Query: 734 RIEGEG---------SVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSKA 784
++E + +++ +++ Q +E E Q +Q+VRELE +Y + Q LE +
Sbjct: 380 QVELQARFSTELEREKLIRQQMEEQVAQKSSELE-QYLQRVRELEDMYLKLQEALEDERQ 438
Query: 785 QQLAEVEVKKFK 796
+ E V+K +
Sbjct: 439 ARQDEETVRKLQ 450
Score = 41.2 bits (95), Expect = 0.004
Identities = 63/238 (26%), Positives = 109/238 (45%), Gaps = 30/238 (12%)
Query: 623 RDQAVFPQNGLVVSSVDVQSVEPVDQRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQ 682
R + + Q L ++Q+ Q+ +A+++ ++ E + + E K ++E
Sbjct: 327 RKKQLAEQEELERQMKELQAANESKQQELEAVRKKLE---EAASRAAEEEKKRLQTQVEL 383
Query: 683 EAR--GRLERQKILDQSEAEKARKELLELE--------------ALSMAVESTGTAKAEA 726
+AR LER+K++ Q E+ ++ ELE L A+E A+ +
Sbjct: 384 QARFSTELEREKLIRQQMEEQVAQKSSELEQYLQRVRELEDMYLKLQEALEDERQARQDE 443
Query: 727 ES-RAEAARIEGEGSVLQAKLK----AQALAIE-TEAELQRVQKVRELE---LVYARAQL 777
E+ R AR+ E S +A+L+ Q AI+ TEAE Q ++ R L+ L A QL
Sbjct: 444 ETVRKLQARLLEEESSKRAELEKWHLEQQQAIQTTEAEKQELENQRVLKEQALQEAMEQL 503
Query: 778 E-LEVSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLKSTLITD 834
E LE+ + Q L + E K K++ A + VA E ++L++ LIT+
Sbjct: 504 EQLELERKQALEQYEEVK-KKLEMATNKTKSWKDKVAHHEGLIRLIEPGSKNPHLITN 560
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 43.5 bits (101), Expect = 9e-04
Identities = 48/158 (30%), Positives = 78/158 (49%), Gaps = 11/158 (6%)
Query: 669 QEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAES 728
+E K E + E+E R R E + Q E + ++EL L+ E T + + E+
Sbjct: 826 EEEKKKREEEERERE-RERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKEN 884
Query: 729 RA--EAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSKAQQ 786
+ E R+E E LQ + Q L++ TEA LQ++Q+ R+ EL +LE E +A Q
Sbjct: 885 KQVEEILRLEKEIEDLQRMKEQQELSL-TEASLQKLQERRDQEL----RRLEEEACRAAQ 939
Query: 787 LAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQS 824
+E F ++ E + + R L+V G E +L +S
Sbjct: 940 -EFLESLNFDEIDECV-RNIERSLSV-GSEFSSELAES 974
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 42.7 bits (99), Expect = 0.001
Identities = 40/160 (25%), Positives = 81/160 (50%), Gaps = 9/160 (5%)
Query: 641 QSVEPVDQRTRDA-LQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEA 699
+++E + R R+ QR L ++ +++Q A + R EQEA + R+++ Q +A
Sbjct: 653 KAIEEEEARMREEESQRLSWLRAQVQSSTQ---ADEDQIRAEQEASLQKLREELESQQKA 709
Query: 700 EKA---RKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETE 756
E+A +K LE L +E++ ++ A + A+ ++ L+ + K +E E
Sbjct: 710 ERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKE 769
Query: 757 --AELQRVQKVRELELVYARAQLELEVSKAQQLAEVEVKK 794
AEL+R+ E + + L+ ++ +AQQ E +++K
Sbjct: 770 HSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQK 809
Score = 37.0 bits (84), Expect = 0.082
Identities = 35/163 (21%), Positives = 67/163 (41%), Gaps = 1/163 (0%)
Query: 641 QSVEPVDQRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLER-QKILDQSEA 699
Q +E + ++ Q +Q E +E Q+ EQ ER QK +++ EA
Sbjct: 601 QVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEA 660
Query: 700 EKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAEL 759
+E L L V+S+ A + + A ++ L+++ KA+ ++E +
Sbjct: 661 RMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQ 720
Query: 760 QRVQKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAI 802
Q E+E Q L +K + L ++ + + EA+
Sbjct: 721 MLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAV 763
Score = 35.8 bits (81), Expect = 0.18
Identities = 45/188 (23%), Positives = 90/188 (47%), Gaps = 23/188 (12%)
Query: 623 RDQAVFPQNGLVVS-----SVDVQSVEPV---DQRTRDALQRSVQLAIEITTNSQEAAAK 674
+++A P+ + VS S +V+S EPV +Q + AL+ + ++ Q +
Sbjct: 553 QEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLE 612
Query: 675 HEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAAR 734
+ ++++Q R+K+ + E +E+L L S+ + + E AR
Sbjct: 613 SKQEKMQQL------REKLCQEEE-----EEILRLHQQKEQSLSSLRERLQKAIEEEEAR 661
Query: 735 IEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSKAQQLAEVEVKK 794
+ E S + L+AQ + T+A+ +++ +E L R +LE + KA++ A +E +K
Sbjct: 662 MREEESQRLSWLRAQVQS-STQADEDQIRAEQEASLQKLREELESQ-QKAER-ASLE-QK 717
Query: 795 FKQMTEAI 802
+QM E +
Sbjct: 718 NRQMLEQL 725
Score = 33.1 bits (74), Expect = 1.2
Identities = 34/144 (23%), Positives = 65/144 (45%), Gaps = 7/144 (4%)
Query: 643 VEPVDQRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLE--RQKILDQSEAE 700
V+ Q D ++ + +++ E+ K E LEQ+ R LE +++I ++E
Sbjct: 677 VQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSE 736
Query: 701 KARKELLELEALSMAVESTGTAKAEAESRAE---AARIEGEGSVLQAKLKAQALAIETEA 757
+A + +AL E + EA + E +A +E S L+AK + +++ +
Sbjct: 737 QAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKK- 795
Query: 758 ELQRVQKVRELELVYARAQLELEV 781
+Q Q+ E +L Q+E V
Sbjct: 796 -IQEAQQKEEAQLQKCLGQVEHRV 818
Score = 33.1 bits (74), Expect = 1.2
Identities = 41/190 (21%), Positives = 74/190 (38%), Gaps = 16/190 (8%)
Query: 641 QSVEPVDQRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAE 700
Q VE +R D ++ Q + EA + + L G LER + + E E
Sbjct: 841 QEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELE 900
Query: 701 KARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQ 760
R+E +E E E + + ++ E K + L ++ E +
Sbjct: 901 TVRQE------QHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARR 954
Query: 761 RVQKVRELELVYARAQLELEVSKAQQLAEVE------VKKFKQMTEAIGPSTIRDLAVAG 814
Q++ +++ A + E + QQL E + ++ +Q+ E + R L +
Sbjct: 955 EKQQLLDVQRQVA-LKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKL-- 1011
Query: 815 PEMQVKLLQS 824
E QV LLQ+
Sbjct: 1012 -ESQVDLLQA 1020
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 42.7 bits (99), Expect = 0.001
Identities = 40/137 (29%), Positives = 68/137 (49%), Gaps = 10/137 (7%)
Query: 670 EAAAKHEAQRLEQEARGRLER----QKILDQSEAEK--ARKELLELEALSMAVEST--GT 721
EAAA + Q+L+ E R ER Q+ L Q EAEK + L LE +A+ T
Sbjct: 1826 EAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKV 1885
Query: 722 AKAEAESRAEAARIEGEGSVLQAKLKAQALAI-ETEAELQRVQ-KVRELELVYARAQLEL 779
+ + S + R+ E L L L + E + ++Q+++ +V LE ++ AQLE+
Sbjct: 1886 EREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEV 1945
Query: 780 EVSKAQQLAEVEVKKFK 796
+ + Q + EV++ +
Sbjct: 1946 DAQQQQLELQQEVERLR 1962
Score = 42.0 bits (97), Expect = 0.003
Identities = 68/258 (26%), Positives = 103/258 (39%), Gaps = 56/258 (21%)
Query: 619 LPRPRDQAVFPQNGLVVSSVDVQSVEPVDQRTRDALQRSVQLAIEITTNSQEAAAKHEAQ 678
LP R + Q L S + E ++ R QR V+ A+E +EA AK A
Sbjct: 822 LPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVE-ALERAAREKEALAKEHAG 880
Query: 679 RLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGE 738
Q E + + +E+A + LE EAL ++ A+ E+R E EG+
Sbjct: 881 LAVQLVAAEREGRTL-----SEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQ 935
Query: 739 GSVL-----------------------------------QAKLKAQALAIET----EAEL 759
+L QA+ +AQA E E +L
Sbjct: 936 ALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDL 995
Query: 760 QRVQKVREL---ELVYARAQLELEVSKAQQ--LAEVEVKKFKQMTEAIGPSTIRD--LAV 812
QR+Q+ +E EL RAQL+ ++ + Q+ LA +E +K + E RD L +
Sbjct: 996 QRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLL 1055
Query: 813 AGPEMQVKLLQSLGLKST 830
A E Q Q+L LK +
Sbjct: 1056 AESEKQ----QALSLKES 1069
Score = 35.0 bits (79), Expect = 0.31
Identities = 51/164 (31%), Positives = 80/164 (48%), Gaps = 35/164 (21%)
Query: 653 ALQRSVQLAIEITTNSQEAAAKHEA-----QRLEQE----------ARGRLERQ-KILDQ 696
+LQ + Q A E+ ++ A E RLE+E R LER + L+Q
Sbjct: 611 SLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQ 670
Query: 697 SEAEKA--RKELLEL-EALSMA------VESTGTAKAEAESRAEAARIEGEGSVLQAKLK 747
E +++ KEL+E+ EALS A +++ AEA ++AEA R+E E S+ KL+
Sbjct: 671 LEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSM--TKLR 728
Query: 748 AQALAIETEAELQRVQKVRE------LELVYARAQLELEVSKAQ 785
A+ +++ L ++ + E L+L AQLE E S Q
Sbjct: 729 AEEASLQD--SLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQ 770
Score = 34.3 bits (77), Expect = 0.53
Identities = 58/250 (23%), Positives = 102/250 (40%), Gaps = 36/250 (14%)
Query: 615 DGMALPRPRDQAVFPQNGLVVSSVDVQSVEPVDQRTRDALQRSVQLAIEITTNSQEAAAK 674
+G AL ++ GL + Q +D+ Q+ VQ E + +E A
Sbjct: 933 EGQALLLAKETLTGELAGLRQQIIATQEKASLDKELM--AQKLVQAEREAQASLREQRAA 990
Query: 675 HEA--QRLEQEARG---RLERQKILDQSEAEKARKELL-----ELEALSMAVEST----- 719
HE QRL++E LE ++ QS+ ++ ++ELL E E LS + +
Sbjct: 991 HEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERD 1050
Query: 720 -GTAKAEAESRAEAARIEGEGSVLQAKL-----KAQALAIETEAELQRVQKVRELE---- 769
G AE+E + + E E + L KL +++E E + + Q +E +
Sbjct: 1051 EGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTV 1110
Query: 770 --LVYARAQLELEVSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPE---MQVKLLQS 824
L L + +A EV++ ++ +G RD + E Q++LL+
Sbjct: 1111 NALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQ--RDSCLREAEELRTQLRLLED 1168
Query: 825 L--GLKSTLI 832
GL+ L+
Sbjct: 1169 ARDGLRRELL 1178
Score = 32.7 bits (73), Expect = 1.5
Identities = 32/140 (22%), Positives = 67/140 (47%), Gaps = 10/140 (7%)
Query: 648 QRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELL 707
++ R AL+R++ S E + A++ GRL+R + E +A++++
Sbjct: 1872 EKDRVALRRTLDKVEREKLRSHEDTVRLSAEK------GRLDRTLTGAELELAEAQRQIQ 1925
Query: 708 ELEALSMAVE-STGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVR 766
+LEA + +E S A+ E +++ + ++ E L++ +E R Q+VR
Sbjct: 1926 QLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERLRSAQAQTERTLEARERAHR-QRVR 1984
Query: 767 ELE--LVYARAQLELEVSKA 784
LE + + QL+ E+ ++
Sbjct: 1985 GLEEQVSTLKGQLQQELRRS 2004
Score = 32.0 bits (71), Expect = 2.6
Identities = 44/145 (30%), Positives = 73/145 (50%), Gaps = 12/145 (8%)
Query: 655 QRSVQL---AIEITTNSQEAAAKHEAQRLEQEARG-RLERQKILDQSEAEKARKELLELE 710
QR VQ A E+ + + A H Q +Q+A R ER+K+ E + +++ LE E
Sbjct: 588 QREVQRLRSANELLSREKSNLA-HSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLE-E 645
Query: 711 ALSMAVESTGTAKAEAE-SRAEAARIEGEGSVLQAKL--KAQALAIET-EAELQRVQKVR 766
AV+ + E E S + ++EG+ SVL +L +AL+ T + ++ + +K
Sbjct: 646 EQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAE 705
Query: 767 ELE-LVYARA-QLELEVSKAQQLAE 789
E L A A ++ELE+S + AE
Sbjct: 706 VAEALTKAEAGRVELELSMTKLRAE 730
Score = 31.2 bits (69), Expect = 4.5
Identities = 56/231 (24%), Positives = 85/231 (36%), Gaps = 37/231 (16%)
Query: 651 RDALQRSVQLAIEITTNSQEAAAKHEAQRL-EQEARGRLERQKILDQSEAEKARKELLEL 709
RD LQ +LA + RL E A LE+Q +L E+ R ++L
Sbjct: 319 RDLLQLGGELARTSRAVQEAGLGLSTGLRLAESRAEAALEKQALLQAQLEEQLRDKVLRE 378
Query: 710 EALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELE 769
+ L+ + KA+ +R E + +L+ Q L + + +K+ LE
Sbjct: 379 KDLAQQQMQSDLDKADLSARVT------ELGLAVKRLEKQNLE-KDQVNKDLTEKLEALE 431
Query: 770 LVYARAQLELEVSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLKS 829
+ + Q LE + L + T+RDLA A +Q G +
Sbjct: 432 SLRLQEQAALETEDGEGLQQ----------------TLRDLAQAVLSDSESGVQLSGSER 475
Query: 830 TLITDGSTPINLFNTAFGLLGMGPEGQPLGRRVASGPSPGEGISPQSAQAP 880
T D S + GL G P RR SPG G SP+ +P
Sbjct: 476 T--ADASN-----GSLRGLSGQRTPSPP--RR----SSPGRGRSPRRGPSP 513
Score = 30.8 bits (68), Expect = 5.9
Identities = 38/157 (24%), Positives = 70/157 (44%), Gaps = 15/157 (9%)
Query: 650 TRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQE--------ARGRLERQKILDQSEAEK 701
TR+ Q + + T + + + E Q L+QE A+ R ER ++ + A
Sbjct: 56 TRNLSQPESPVLLPATEMASLLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVS 115
Query: 702 ARKE-LLELEALSMAV-ESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAEL 759
R E L LE + E G + E R + ++ E + + KL+A + +A+L
Sbjct: 116 ERLEQALRLEPGELETQEPRGLVRQSVELRRQ---LQEEQASYRRKLQAYQEGQQRQAQL 172
Query: 760 QRVQKVRELELVYARAQLELEVSKAQQLAEVEVKKFK 796
VQ+++ L Y + ELE ++ E+E ++ +
Sbjct: 173 --VQRLQGKILQYKKRCSELEQQLLERSGELEQQRLR 207
>gi|4504063 golgin 97 [Homo sapiens]
Length = 767
Score = 42.7 bits (99), Expect = 0.001
Identities = 50/183 (27%), Positives = 88/183 (48%), Gaps = 19/183 (10%)
Query: 648 QRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQE------ARGRLERQKILDQSEAEK 701
+RT+ AL+ + +A+E T + + A+ ++LEQE R ER Q E +K
Sbjct: 410 ERTQ-ALEAQI-VALERTRAADQTTAEQGMRQLEQENAALKECRNEYERSLQNHQFELKK 467
Query: 702 ARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKL--KAQALAIETEAEL 759
++E + E +S+A+ A+A E R + + + + L A + K Q L +TE L
Sbjct: 468 LKEEWSQREIVSVAM-----AQALEEVRKQREEFQQQAANLTAIIDEKEQNLREKTEVLL 522
Query: 760 QRVQKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQV 819
Q+ Q++ +LE + A L++ Q AE+E + + EA + DL +Q
Sbjct: 523 QKEQEILQLERGHNSALLQIH----QLQAELEALRTLKAEEAAVVAEQEDLLRLRGPLQA 578
Query: 820 KLL 822
+ L
Sbjct: 579 EAL 581
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 42.7 bits (99), Expect = 0.001
Identities = 58/208 (27%), Positives = 89/208 (42%), Gaps = 43/208 (20%)
Query: 654 LQRSVQLAIEITTNSQEAAAKHEA--QRLEQEARGRLER----QKILDQSEAEKARKELL 707
LQR +QL ++ N +E + A + L + ++E Q+ L++SE E RK L
Sbjct: 626 LQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGE-LRKNLE 684
Query: 708 ELEALSMAVESTGT-----------------AKAEAESRAEAARIEGEGSVLQAKLKAQA 750
EL + M E T + +E R + A IE +LQAK Q
Sbjct: 685 ELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIE---ELLQAKQDLQD 741
Query: 751 LAIETEAELQRVQKVRELELVYARAQLELEVS-------KAQQLAEVEVKKFKQMTEAI- 802
L I E + ++K RE EL + L+ EVS K ++ + E++ ++ E
Sbjct: 742 LLIAKEEQEDLLRK-RERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEAT 800
Query: 803 -------GPSTIRDLAVAGPEMQVKLLQ 823
S + AG EM+VKLLQ
Sbjct: 801 KNVEVLASRSNTSEQDQAGTEMRVKLLQ 828
>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
Length = 749
Score = 42.7 bits (99), Expect = 0.001
Identities = 42/145 (28%), Positives = 65/145 (44%), Gaps = 6/145 (4%)
Query: 665 TTNSQEAAAK-HEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAK 723
TT+ +EA E +RL +E R + ER++ +Q E E+ ++E E E T +
Sbjct: 473 TTDPEEATRLLAEKRRLAREQREKEERER-REQEELERQKRE----ELAQRVAEERTTRR 527
Query: 724 AEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSK 783
E R EA + + LQ + + +AL EAE + QK E + ++ E K
Sbjct: 528 EEESRRLEAEQAREKEEQLQRQAEERALREREEAERAQRQKEEEARVREEAERVRQEREK 587
Query: 784 AQQLAEVEVKKFKQMTEAIGPSTIR 808
Q E E + K+ E I T R
Sbjct: 588 HFQREEQERLERKKRLEEIMKRTRR 612
Score = 31.6 bits (70), Expect = 3.4
Identities = 23/96 (23%), Positives = 50/96 (52%), Gaps = 5/96 (5%)
Query: 644 EPVDQRTRDALQRSVQLAIEITTNSQEAAAKHEAQRL---EQEARGRLERQKILDQSEAE 700
E ++++ R+ L + V A E TT +E + + EA++ E++ + + E + + ++ EAE
Sbjct: 505 EELERQKREELAQRV--AEERTTRREEESRRLEAEQAREKEEQLQRQAEERALREREEAE 562
Query: 701 KARKELLELEALSMAVESTGTAKAEAESRAEAARIE 736
+A+++ E + E + + R E R+E
Sbjct: 563 RAQRQKEEEARVREEAERVRQEREKHFQREEQERLE 598
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 42.7 bits (99), Expect = 0.001
Identities = 36/130 (27%), Positives = 63/130 (48%), Gaps = 23/130 (17%)
Query: 665 TTNSQEAAAKHEAQRLEQEARGRLERQKILDQS---------EAEKARKELLELEALSMA 715
T Q A++E ++L E L+R ++Q +AE RKEL ELE+
Sbjct: 627 TIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELES---- 682
Query: 716 VESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQ-----ALAIETEAELQRVQKVRELEL 770
+ + E A + +G+ S +A+L+A+ A A + + EL++V ++ +LE
Sbjct: 683 -----ALQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKVTRLTQLEQ 737
Query: 771 VYARAQLELE 780
+A+LE E
Sbjct: 738 SALQAELEKE 747
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 42.4 bits (98), Expect = 0.002
Identities = 47/170 (27%), Positives = 81/170 (47%), Gaps = 17/170 (10%)
Query: 674 KHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAA 733
KHEA + E R R E ++ + E EK R++L +ST + AE +A+ A
Sbjct: 1024 KHEAMITDLEERLRREEKQ---RQELEKTRRKL--------EGDSTDLSDQIAELQAQIA 1072
Query: 734 RIEGEGSVLQAKLKAQALAIETEAELQRV--QKVRELELVYARAQLELEVSKA-QQLAEV 790
++ + + + +L+A +E EA + + +K+RELE + Q +LE +A + AE
Sbjct: 1073 ELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEK 1132
Query: 791 EVKKFKQMTEAIGP--STIRDLAVAGPEMQVKLLQSLG-LKSTLITDGST 837
+ + + EA+ D A E++ K Q + LK TL + T
Sbjct: 1133 QKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKT 1182
Score = 31.2 bits (69), Expect = 4.5
Identities = 38/170 (22%), Positives = 75/170 (44%), Gaps = 24/170 (14%)
Query: 650 TRDALQRSVQLAIE-ITTNSQEAAAKHEA-----QRLEQEARGRL-----ERQKILDQSE 698
T + ++R +Q +E ++ +E A ++ RL+QE L +RQ + +
Sbjct: 1382 TAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEK 1441
Query: 699 AEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAE 758
+K +LL E A + +AEAE+R + + L+ A+E +AE
Sbjct: 1442 KQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEE-------AMEQKAE 1494
Query: 759 LQRVQKVRELELVYARAQLE------LEVSKAQQLAEVEVKKFKQMTEAI 802
L+R+ K E+ + + E+ K+++ E +V++ K E +
Sbjct: 1495 LERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEEL 1544
>gi|35038601 spindle assembly abnormal protein 6 [Homo sapiens]
Length = 657
Score = 42.0 bits (97), Expect = 0.003
Identities = 41/153 (26%), Positives = 72/153 (47%), Gaps = 16/153 (10%)
Query: 659 QLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVES 718
QL ++ QE K + +EA ++ QK++ + EK + +L +LEA ++S
Sbjct: 319 QLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEA---TIKS 375
Query: 719 TGTAKAEAESRAEAARIEGEGSVLQAKLK--------AQALAIETEAELQRVQKVRELEL 770
+A + +++G+ L KLK + L E E +LQ+ QK EL+
Sbjct: 376 LSAELLKANEIIK--KLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQK--ELQD 431
Query: 771 VYARAQL-ELEVSKAQQLAEVEVKKFKQMTEAI 802
V ++ E EV K Q+ E VKK ++ + +
Sbjct: 432 VGQSLRIKEQEVCKLQEQLEATVKKLEESKQLL 464
>gi|88196790 coiled-coil domain containing 88 [Homo sapiens]
Length = 1476
Score = 42.0 bits (97), Expect = 0.003
Identities = 50/185 (27%), Positives = 86/185 (46%), Gaps = 20/185 (10%)
Query: 649 RTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQ--KILDQSEAEKARKEL 706
R R+A++ + Q E+ + SQE A EA R + ER+ ++ QSEA + R ++
Sbjct: 792 RLREAVEAAGQ---ELESASQEREALVEALAAAGRERRQWEREGSRLRAQSEAAEERMQV 848
Query: 707 LELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVR 766
LE E E+ + + +AE + G L A+L+ +E +A L+R + +R
Sbjct: 849 LESEGRQHLEEAERERREKEALQAELEKAVVRGKELGARLEHLQRELE-QAALERQEFLR 907
Query: 767 ELELVYARAQ-----LELEV-----SKAQQLAEVEVKKFKQMTEAI----GPSTIRDLAV 812
E E + R Q LE E+ SK + L E++ + + E GP+ +
Sbjct: 908 EKESQHQRYQGLEQRLEAELQAAATSKEEALMELKTRALQLEEELFQLRQGPAGLGPKKR 967
Query: 813 AGPEM 817
A P++
Sbjct: 968 AEPQL 972
Score = 36.6 bits (83), Expect = 0.11
Identities = 41/166 (24%), Positives = 72/166 (43%), Gaps = 19/166 (11%)
Query: 673 AKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAEA 732
A+ EA R E+ A+ R + + + D+ EA+ + E EA ++ E +AEAE+ EA
Sbjct: 725 AEQEALR-EEVAQLRRKAEALGDELEAQARKLEAQNTEAARLSKELAQARRAEAEAHREA 783
Query: 733 -----------ARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEV 781
+E G L++ + + +E A R ++ E E RAQ E
Sbjct: 784 EAQAWEQARLREAVEAAGQELESASQEREALVEALAAAGRERRQWEREGSRLRAQSEAAE 843
Query: 782 SKAQQLAE------VEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKL 821
+ Q L E ++ ++ EA+ + + V G E+ +L
Sbjct: 844 ERMQVLESEGRQHLEEAERERREKEAL-QAELEKAVVRGKELGARL 888
>gi|5031699 flotillin 1 [Homo sapiens]
Length = 427
Score = 41.6 bits (96), Expect = 0.003
Identities = 53/232 (22%), Positives = 95/232 (40%), Gaps = 34/232 (14%)
Query: 582 AVASVTFDDFHKN-----------SARIIRTAVFGFETSEAKGPDGMALPRPRDQAVFPQ 630
+V S T D H + +A++ + A G +EAK G+ + + + V Q
Sbjct: 145 SVVSYTLKDIHDDQDYLHSLGKARTAQVQKDARIG--EAEAKRDAGIREAKAKQEKVSAQ 202
Query: 631 NGLVVSSVDVQ----------SVEPVDQRTRDALQRSVQLAI---EITTNSQEAAAKHEA 677
+ Q +E +R + L +Q+A +I + A
Sbjct: 203 YLSEIEMAKAQRDYELKKAAYDIEVNTRRAQADLAYQLQVAKTKQQIEEQRVQVQVVERA 262
Query: 678 QRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEG 737
Q++ + + R+K L+ + A E +LE L+ A +S +AEAE+ + R E
Sbjct: 263 QQVAVQEQEIARREKELEARVRKPAEAERYKLERLAEAEKSQLIMQAEAEAASVRMRGEA 322
Query: 738 EGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSKAQQLAE 789
E + A+ +A+A Q +K +L AQL++ + K Q+AE
Sbjct: 323 EAFAIGARARAEA--------EQMAKKAEAFQLYQEAAQLDMLLEKLPQVAE 366
Score = 31.6 bits (70), Expect = 3.4
Identities = 40/183 (21%), Positives = 79/183 (43%), Gaps = 25/183 (13%)
Query: 632 GLVVSSVDVQSVEPVDQRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQ 691
G+ V S ++ + DQ +L ++ ++ EA AK +A E +A+
Sbjct: 143 GISVVSYTLKDIHD-DQDYLHSLGKARTAQVQKDARIGEAEAKRDAGIREAKAKQEKVSA 201
Query: 692 KILDQSEAEKARKELLELEALSMAVE-STGTAKAEAESRAEAAR----IEGEGSVLQAKL 746
+ L + E KA+++ EL+ + +E +T A+A+ + + A+ IE + +Q
Sbjct: 202 QYLSEIEMAKAQRDY-ELKKAAYDIEVNTRRAQADLAYQLQVAKTKQQIEEQRVQVQVVE 260
Query: 747 KAQALAIE------------------TEAELQRVQKVRELELVYARAQLELEVSKAQQLA 788
+AQ +A++ EAE +++++ E E Q E E + +
Sbjct: 261 RAQQVAVQEQEIARREKELEARVRKPAEAERYKLERLAEAEKSQLIMQAEAEAASVRMRG 320
Query: 789 EVE 791
E E
Sbjct: 321 EAE 323
>gi|4505257 moesin [Homo sapiens]
Length = 577
Score = 41.6 bits (96), Expect = 0.003
Identities = 38/139 (27%), Positives = 68/139 (48%), Gaps = 8/139 (5%)
Query: 648 QRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARG-RLERQKILDQSEAEKARKEL 706
++ ++ ++R + +E +E K + + EQ R LE+++ QSEAEK KE
Sbjct: 334 EKEKEKIEREKEELMERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKER 393
Query: 707 LELEALSMAV--ESTGTAKAEAESRAEAARIEGEGSVLQ-AKLKAQALAIETEAELQRVQ 763
E E A+ S K + + E A + S L+ A+ K ++ A+E + + Q VQ
Sbjct: 394 QEAEEAKEALLQASRDQKKTQEQLALEMAELTARISQLEMARQKKESEAVEWQQKAQMVQ 453
Query: 764 KVRELELVYARAQLELEVS 782
+ +L RA+L+ +S
Sbjct: 454 E----DLEKTRAELKTAMS 468
Score = 38.9 bits (89), Expect = 0.022
Identities = 43/161 (26%), Positives = 87/161 (54%), Gaps = 15/161 (9%)
Query: 637 SVDVQSVEPVDQRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQ 696
+++VQ ++ Q + Q+ ++ A+ + A+ E +++E+E +ER K +++
Sbjct: 299 TIEVQQMKA--QAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEELMERLKQIEE 356
Query: 697 SEAEKARKELLELEALSMAVE-STGTAKAEAESRAEAAR--IEGEGSVLQA----KLKAQ 749
+ +KA++EL E ++ +E A++EAE A+ + E + ++LQA K +
Sbjct: 357 -QTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQE 415
Query: 750 ALAIETEAELQRVQKVRELELVYARAQLELEVSKAQQLAEV 790
LA+E AEL ++ +LE+ AR + E E + QQ A++
Sbjct: 416 QLALEM-AEL--TARISQLEM--ARQKKESEAVEWQQKAQM 451
>gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo
sapiens]
Length = 551
Score = 41.6 bits (96), Expect = 0.003
Identities = 42/177 (23%), Positives = 77/177 (43%), Gaps = 25/177 (14%)
Query: 646 VDQRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARK- 704
+DQ Q+S+Q E+ +E + Q +EQ + + ER + +Q E EK +
Sbjct: 228 LDQMMEVERQKSIQRQEELERKRREERIRGRRQIVEQMEKNQEERSLLAEQREQEKEQML 287
Query: 705 ELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQ--------------- 749
E +E + + + + +AE RI E +A+L AQ
Sbjct: 288 EYMEQLQEEDLKDMERRQQQKLKMQAEIKRINDENQKQKAELLAQEKLADQMVMEFTKKK 347
Query: 750 -ALAIETEAELQRVQKVRELELVYARA--------QLELEVSKAQQLAEVEVKKFKQ 797
A E EAE +R+++ +E E+ RA Q E + +A++ EV +++++
Sbjct: 348 MAREAEFEAEQERIRREKEKEIARLRAMQEKAQDYQAEQDALRAKRNQEVADREWRR 404
Score = 30.8 bits (68), Expect = 5.9
Identities = 38/143 (26%), Positives = 64/143 (44%), Gaps = 18/143 (12%)
Query: 669 QEAAAKHEAQRLEQEAR--GRLERQKILDQSEAE-KARKELLELEALSMAVESTGTAKAE 725
+E A+ +A + E+EA + R+KI+ Q E K+L +LE + AK
Sbjct: 122 EELEARDQAFKKEKEATMDAVMTRKKIMKQKEMVWNNNKKLSDLEEV---------AKER 172
Query: 726 AES---RAEAARIEGEGSVLQAK---LKAQALAIETEAELQRVQKVRELELVYARAQLEL 779
A++ RA R+E E + L A+ AI L++ Q +EL+ R +
Sbjct: 173 AQNLLQRANKLRMEQEEELKDMSKIILNAKCHAIRDAQILEKQQIQKELDTEEKRLDQMM 232
Query: 780 EVSKAQQLAEVEVKKFKQMTEAI 802
EV + + + E + K+ E I
Sbjct: 233 EVERQKSIQRQEELERKRREERI 255
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,893,811
Number of Sequences: 37866
Number of extensions: 1587883
Number of successful extensions: 6724
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 289
Number of HSP's that attempted gapping in prelim test: 5863
Number of HSP's gapped (non-prelim): 945
length of query: 893
length of database: 18,247,518
effective HSP length: 111
effective length of query: 782
effective length of database: 14,044,392
effective search space: 10982714544
effective search space used: 10982714544
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.