BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|19913408 DNA topoisomerase II, beta isozyme [Homo sapiens] (1621 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|19913408 DNA topoisomerase II, beta isozyme [Homo sapiens] 3262 0.0 gi|19913406 DNA topoisomerase II, alpha isozyme [Homo sapiens] 2112 0.0 gi|55956788 nucleolin [Homo sapiens] 62 3e-09 gi|217330641 IWS1 homolog [Homo sapiens] 62 5e-09 gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 59 4e-08 gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 55 6e-07 gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 54 9e-07 gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 54 9e-07 gi|16445033 ACRC protein [Homo sapiens] 54 9e-07 gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 54 1e-06 gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 54 1e-06 gi|59814411 hypothetical protein LOC253725 [Homo sapiens] 52 4e-06 gi|55741677 SET domain containing 1A [Homo sapiens] 52 5e-06 gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 51 8e-06 gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi... 50 1e-05 gi|48255931 hepatoma-derived growth factor-related protein 2 iso... 50 2e-05 gi|14249158 hepatoma-derived growth factor-related protein 2 iso... 50 2e-05 gi|210032580 SET domain containing 1B [Homo sapiens] 49 3e-05 gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 49 3e-05 gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform... 49 4e-05 gi|38788333 remodeling and spacing factor 1 [Homo sapiens] 49 5e-05 gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora... 48 7e-05 gi|54124343 hypothetical protein LOC387680 [Homo sapiens] 48 7e-05 gi|104526627 triadin [Homo sapiens] 48 7e-05 gi|154090959 hypothetical protein LOC55747 [Homo sapiens] 48 7e-05 gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 48 9e-05 gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 48 9e-05 gi|150170670 piccolo isoform 2 [Homo sapiens] 48 9e-05 gi|150378539 piccolo isoform 1 [Homo sapiens] 48 9e-05 gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa... 47 1e-04 >gi|19913408 DNA topoisomerase II, beta isozyme [Homo sapiens] Length = 1621 Score = 3262 bits (8458), Expect = 0.0 Identities = 1621/1621 (100%), Positives = 1621/1621 (100%) Query: 1 MAKSGGCGAGAGVGGGNGALTWVNNAAKKEESETANKNDSSKKLSVERVYQKKTQLEHIL 60 MAKSGGCGAGAGVGGGNGALTWVNNAAKKEESETANKNDSSKKLSVERVYQKKTQLEHIL Sbjct: 1 MAKSGGCGAGAGVGGGNGALTWVNNAAKKEESETANKNDSSKKLSVERVYQKKTQLEHIL 60 Query: 61 LRPDTYIGSVEPLTQFMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTC 120 LRPDTYIGSVEPLTQFMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTC Sbjct: 61 LRPDTYIGSVEPLTQFMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTC 120 Query: 121 IKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNG 180 IKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNG Sbjct: 121 IKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNG 180 Query: 181 YGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLS 240 YGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLS Sbjct: 181 YGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLS 240 Query: 241 KFKMEKLDKDIVALMTRRAYDLAGSCRGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGV 300 KFKMEKLDKDIVALMTRRAYDLAGSCRGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGV Sbjct: 241 KFKMEKLDKDIVALMTRRAYDLAGSCRGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGV 300 Query: 301 ALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKK 360 ALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKK Sbjct: 301 ALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKK 360 Query: 361 NKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASN 420 NKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASN Sbjct: 361 NKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASN 420 Query: 421 CGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDS 480 CGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDS Sbjct: 421 CGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDS 480 Query: 481 AKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDD 540 AKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDD Sbjct: 481 AKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDD 540 Query: 541 AESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNK 600 AESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNK Sbjct: 541 AESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNK 600 Query: 601 QELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPE 660 QELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPE Sbjct: 601 QELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPE 660 Query: 661 DDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELI 720 DDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELI Sbjct: 661 DDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELI 720 Query: 721 LFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQAL 780 LFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQAL Sbjct: 721 LFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQAL 780 Query: 781 MMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSTLARLLFPAVDDN 840 MMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSTLARLLFPAVDDN Sbjct: 781 MMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSTLARLLFPAVDDN 840 Query: 841 LLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGLD 900 LLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGLD Sbjct: 841 LLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGLD 900 Query: 901 PHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPML 960 PHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPML Sbjct: 901 PHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPML 960 Query: 961 NGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFD 1020 NGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFD Sbjct: 961 NGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFD 1020 Query: 1021 HMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKIT 1080 HMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKIT Sbjct: 1021 HMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKIT 1080 Query: 1081 IENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEDETQNQHDDSSSDSGTPSGPDFNY 1140 IENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEDETQNQHDDSSSDSGTPSGPDFNY Sbjct: 1081 IENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEDETQNQHDDSSSDSGTPSGPDFNY 1140 Query: 1141 ILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVESQERE 1200 ILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVESQERE Sbjct: 1141 ILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVESQERE 1200 Query: 1201 DVLAGMSGKAIKGKVGKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKKKGDL 1260 DVLAGMSGKAIKGKVGKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKKKGDL Sbjct: 1201 DVLAGMSGKAIKGKVGKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKKKGDL 1260 Query: 1261 DTAAVKVEFDEEFSGAPVEGAGEEALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPS 1320 DTAAVKVEFDEEFSGAPVEGAGEEALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPS Sbjct: 1261 DTAAVKVEFDEEFSGAPVEGAGEEALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPS 1320 Query: 1321 AKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDD 1380 AKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDD Sbjct: 1321 AKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDD 1380 Query: 1381 DDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFG 1440 DDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFG Sbjct: 1381 DDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFG 1440 Query: 1441 NLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVP 1500 NLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVP Sbjct: 1441 NLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVP 1500 Query: 1501 KPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTS 1560 KPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTS Sbjct: 1501 KPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTS 1560 Query: 1561 KTTSKKPKKTSFDQDSDVDIFPSDFPTEPPSLPRTGRARKEVKYFAESDEEEDDVDFAMF 1620 KTTSKKPKKTSFDQDSDVDIFPSDFPTEPPSLPRTGRARKEVKYFAESDEEEDDVDFAMF Sbjct: 1561 KTTSKKPKKTSFDQDSDVDIFPSDFPTEPPSLPRTGRARKEVKYFAESDEEEDDVDFAMF 1620 Query: 1621 N 1621 N Sbjct: 1621 N 1621 >gi|19913406 DNA topoisomerase II, alpha isozyme [Homo sapiens] Length = 1531 Score = 2112 bits (5471), Expect = 0.0 Identities = 1091/1599 (68%), Positives = 1259/1599 (78%), Gaps = 96/1599 (6%) Query: 25 NAAKKEESETANKNDSSKKLSVERVYQKKTQLEHILLRPDTYIGSVEPLTQFMWVYDEDV 84 N KK E D+ K+LSVER+YQKKTQLEHILLRPDTYIGSVE +TQ MWVYDEDV Sbjct: 16 NKIKKNE-------DAKKRLSVERIYQKKTQLEHILLRPDTYIGSVELVTQQMWVYDEDV 68 Query: 85 GMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTCIKVSIDPESNIISIWNNGKGIPVV 144 G+N REVTFVPGLYKIFDEILVNAADNKQRD M+CI+V+IDPE+N+ISIWNNGKGIPVV Sbjct: 69 GINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVV 128 Query: 145 EHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVETACKEYKH 204 EHKVEK+YVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVETA +EYK Sbjct: 129 EHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKK 188 Query: 205 SFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLSKFKMEKLDKDIVALMTRRAYDLAG 264 FKQTWM+NM + E ++K F+GEDYTCITFQPDLSKFKM+ LDKDIVALM RRAYD+AG Sbjct: 189 MFKQTWMDNMGRAGEMELKPFNGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAG 248 Query: 265 SCRGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGVALKVIHELANERWDVCLTLSEKGF 324 S + VKV NG KLPV GFRSYVD+Y+KDKLDETG +LKVIHE N RW+VCLT+SEKGF Sbjct: 249 STKDVKVFLNGNKLPVKGFRSYVDMYLKDKLDETGNSLKVIHEQVNHRWEVCLTMSEKGF 308 Query: 325 QQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKKNKAGVSVKPFQVKNHIWVFINCLI 384 QQISFVNSIAT+KGGRHVDYV DQ+V KL++VVKKKNK GV+VK QVKNH+W+F+N LI Sbjct: 309 QQISFVNSIATSKGGRHVDYVADQIVTKLVDVVKKKNKGGVAVKAHQVKNHMWIFVNALI 368 Query: 385 ENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASNCGIVESILNWVKFKAQTQLNKKCS 444 ENPTFDSQTKENMTLQPKSFGS CQLSEKF KAA CGIVESILNWVKFKAQ QLNKKCS Sbjct: 369 ENPTFDSQTKENMTLQPKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQVQLNKKCS 428 Query: 445 SVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDSAKSLAVSGLGVIGRDRYGVFPLRG 504 +VK+++IKGIPKLDDANDAGG++S ECTLILTEGDSAK+LAVSGLGV+GRD+YGVFPLRG Sbjct: 429 AVKHNRIKGIPKLDDANDAGGRNSTECTLILTEGDSAKTLAVSGLGVVGRDKYGVFPLRG 488 Query: 505 KILNVREASHKQIMENAEINNIIKIVGLQYKKSYDDAESLKTLRYGKIMIMTDQDQDGSH 564 KILNVREASHKQIMENAEINNIIKIVGLQYKK+Y+D +SLKTLRYGKIMIMTDQDQDGSH Sbjct: 489 KILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMTDQDQDGSH 548 Query: 565 IKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNKQELSFYSIPEFDEWKKHIENQKAW 624 IKGLLINFIHHNWPSLL+H FLEEFITPIVK SKNKQE++FYS+PEF+EWK N K W Sbjct: 549 IKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKSSTPNHKKW 608 Query: 625 KIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPEDDAAITLAFSKKKIDDRKEWLTNF 684 K+KYYKGLGTST+KEAKEYFADM+RHRI F+Y+GPEDDAAI+LAFSKK+IDDRKEWLTNF Sbjct: 609 KVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDDRKEWLTNF 668 Query: 685 MEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELILFSNSDNERSIPSLVDGFKPGQRK 744 MEDRRQR+L GLPE +LYG T +LTYNDFINKELILFSNSDNERSIPS+VDG KPGQRK Sbjct: 669 MEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVDGLKPGQRK 728 Query: 745 VLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQALMMTIVNLAQNFVGSNNINLLQPIG 804 VLFTCFKRNDKREVKVAQLAGSVAEMS+YHHGE +LMMTI+NLAQNFVGSNN+NLLQPIG Sbjct: 729 VLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNNLNLLQPIG 788 Query: 805 QFGTRLHGGKDAASPRYIFTMLSTLARLLFPAVDDNLLKFLYDDNQRVEPEWYIPIIPMV 864 QFGTRLHGGKD+ASPRYIFTMLS+LARLLFP DD+ LKFLYDDNQRVEPEWYIPIIPMV Sbjct: 789 QFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLKFLYDDNQRVEPEWYIPIIPMV 848 Query: 865 LINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGLDPHPMLPNYKNFKGTIQELGQNQYA 924 LINGAEGIGTGW+CK+PN+D REIVNN+RR++DG +P PMLP+YKNFKGTI+EL NQY Sbjct: 849 LINGAEGIGTGWSCKIPNFDVREIVNNIRRLMDGEEPLPMLPSYKNFKGTIEELAPNQYV 908 Query: 925 VSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPMLNGTDKTPALISDYKEYHTDTTVKF 984 +SGE+ +++ T+EI+ELPVRTWTQ YKEQVLEPMLNGT+KTP LI+DY+EYHTDTTVKF Sbjct: 909 ISGEVAILNSTTIEISELPVRTWTQTYKEQVLEPMLNGTEKTPPLITDYREYHTDTTVKF 968 Query: 985 VVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFDHMGCLKKYETVQDILKEFFDLRLS 1044 VVKMTEEKLA+AE GLHKVFKLQT+LTCNSMVLFDH+GCLKKY+TV DIL++FF+LRL Sbjct: 969 VVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILRDFFELRLK 1028 Query: 1045 YYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKITIENRSKKDLIQMLVQRGYESDPVK 1104 YYGLRKEWL+GMLGAES KLNNQARFILEKI GKI IEN+ KK+LI++L+QRGY+SDPVK Sbjct: 1029 YYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQRGYDSDPVK 1088 Query: 1105 AWKEAQEKAAEEDETQ---NQHDDSSSDSGTPSGPDFNYILNMSLWSLTKEKVEELIKQR 1161 AWKEAQ+K +E+E + N+ + SDS T SGP FNY+L+M LW LTKEK +EL + R Sbjct: 1089 AWKEAQQKVPDEEENEESDNEKETEKSDSVTDSGPTFNYLLDMPLWYLTKEKKDELCRLR 1148 Query: 1162 DAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVESQEREDVLAGMSGKAIKGKVGKPKVK 1221 + K +E++ LKRKSPSDLWKEDLA F+EEL+ VE++E++D G+ GK GK K K Sbjct: 1149 NEKEQELDTLKRKSPSDLWKEDLATFIEELEAVEAKEKQDEQVGLPGKG-----GKAKGK 1203 Query: 1222 KLQLEETMPSPYGRRIIPEITA-MKADASKKLLKKKKGDLDTAAVKVEFDEEFSGAPVEG 1280 K Q+ E +PSP G+R+IP IT MKA+A KK KK K + E + G +EG Sbjct: 1204 KTQMAEVLPSPRGQRVIPRITIEMKAEAEKKNKKKIKNE------NTEGSPQEDGVELEG 1257 Query: 1281 AGEEALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSESD 1340 + K++K+EPGT+ +K T + KP KK KKRNPWSD ES SD Sbjct: 1258 LKQRL------------EKKQKREPGTKTKKQTTLAFKP-IKKGKKRNPWSDSESDRSSD 1304 Query: 1341 LEETEPVVIPRDSLLRRAAAERPKYTFDFSEEED-DDADDDDDDNNDLEELKVKASPITN 1399 E+ V PR++ RRAA + K+T D +ED D D+ DD Sbjct: 1305 --ESNFDVPPRETEPRRAAT-KTKFTMDLDSDEDFSDFDEKTDD---------------- 1345 Query: 1400 DGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKF 1459 ++FVPSD SP K+K +P+ S + K Q S E D K Sbjct: 1346 ---EDFVPSDA--------SPPKTKTSPKLSNKELKPQK--------SVVSDLEADDVKG 1386 Query: 1460 DSNEEDSASVFSPSFGLKQTDKVPSKTV-----AAKKGKPSSDTVPKPKRAPKQKKVVEA 1514 S + T+ VP K V AAK +S T K + APK K A Sbjct: 1387 SVPLSSSPPATHFPDETEITNPVPKKNVTVKKTAAKSQSSTSTTGAKKRAAPKGTKRDPA 1446 Query: 1515 VNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTSKT-TSKKPKKTSFD 1573 +NS G+ +K K K R +KRK S S+ + D N + SK TSKK K S D Sbjct: 1447 LNS------GVSQKPDPAKTKNR--RKRKPSTSD-DSDSNFEKIVSKAVTSKKSKGESDD 1497 Query: 1574 QDSDVDIFPSDFPTEPPSLPRTGRARKEVKYFAESDEEE 1612 F DF + ++ RA+K +KY ESDE++ Sbjct: 1498 -------FHMDFDSAVAPRAKSVRAKKPIKYLEESDEDD 1529 Score = 41.2 bits (95), Expect = 0.008 Identities = 65/270 (24%), Positives = 110/270 (40%), Gaps = 41/270 (15%) Query: 1369 FSEEEDDDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPE 1428 + E + D+++++ +D E+ K+ +T+ G P+ D + K K Sbjct: 1090 WKEAQQKVPDEEENEESDNEKETEKSDSVTDSG-----PTFNYLLDMPLWYLTKEKKDEL 1144 Query: 1429 KSLHDKKSQDFGNLFSFPSYSQKSEDDSAKF-------DSNEEDSASVFSPSFGLKQTDK 1481 L ++K Q+ L S S ++D A F ++ E+ V P G K K Sbjct: 1145 CRLRNEKEQELDTL-KRKSPSDLWKEDLATFIEELEAVEAKEKQDEQVGLPGKGGKAKGK 1203 Query: 1482 VP--SKTVAAKKGK---PSSDTVPKPKRAPKQKKVVEAVNSD-SDSEFGIPKKTTTPKGK 1535 ++ + + +G+ P K + K KK ++ N++ S E G+ + Sbjct: 1204 KTQMAEVLPSPRGQRVIPRITIEMKAEAEKKNKKKIKNENTEGSPQEDGVELE------- 1256 Query: 1536 GRGAKKRKASGSENEGDYNPGRKTSKTTS------KKPKKTS--FDQDSDVDIFPSDFPT 1587 G K+R + E PG KT K T+ KK KK + D +SD S+F Sbjct: 1257 --GLKQRLEKKQKRE----PGTKTKKQTTLAFKPIKKGKKRNPWSDSESDRSSDESNFDV 1310 Query: 1588 EPPSLPRTGRARKEVKYFAESDEEEDDVDF 1617 PP RA + K+ + D +ED DF Sbjct: 1311 -PPRETEPRRAATKTKFTMDLDSDEDFSDF 1339 >gi|55956788 nucleolin [Homo sapiens] Length = 710 Score = 62.4 bits (150), Expect = 3e-09 Identities = 72/284 (25%), Positives = 115/284 (40%), Gaps = 45/284 (15%) Query: 1237 IIPEITAMKADAS--KKLLKK--KKGDLDTAAVK--VEFDEEFSGAPVEGAGEEALTPSV 1290 +IP+ KA A+ KK++ KK + T A K V ++ + P + A + Sbjct: 47 VIPQKKGKKAAATSAKKVVVSPTKKVAVATPAKKAAVTPGKKAAATPAKKTVTPAKAVTT 106 Query: 1291 PINKGPKP-KREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVI 1349 P KG P K PG + P K + K KK + +++ SE D E+ E Sbjct: 107 PGKKGATPGKALVATPGKKGAAIPAKGAK-NGKNAKKEDSDEEEDDDSEEDEEDDEDEDE 165 Query: 1350 PRDSL---LRRAAAERPKYTFDFSEEEDDDADDDDDDNNDLEELKVKASPITNDGEDEFV 1406 D + +AAA P + E+++DD DDDDD+ +D EE ++ +P + V Sbjct: 166 DEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVV 225 Query: 1407 PSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDS 1466 P K+ A E D + +D + + EDD + D EE+ Sbjct: 226 P-----------VKAKNVAEDEDEEEDDEDEDDDD-------DEDDEDDDDEDDEEEEE- 266 Query: 1467 ASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVPKPKRAPKQKK 1510 + ++ P K K+ K + K K AP+ KK Sbjct: 267 -----------EEEEEPVKEAPGKRKK----EMAKQKAAPEAKK 295 Score = 35.8 bits (81), Expect = 0.35 Identities = 47/199 (23%), Positives = 68/199 (34%), Gaps = 18/199 (9%) Query: 1421 GKSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSAS-VFSPSFGLKQT 1479 GK++ P+K K + + SED+ D ++ S V P K+ Sbjct: 8 GKNQGDPKKMAPPPKEVE-----------EDSEDEEMSEDEEDDSSGEEVVIPQKKGKKA 56 Query: 1480 DKVPSKTVAAKKGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGA 1539 +K V K + P K A K +A + + K TTP KG Sbjct: 57 AATSAKKVVVSPTKKVAVATPAKKAAVTPGK--KAAATPAKKTVTPAKAVTTPGKKGATP 114 Query: 1540 KKRKASGSENEGDYNP--GRKTSKTTSKKPKKTSFDQDSDVDIFPSDFPTEPPSLPRTGR 1597 K + +G P G K K K+ D DS+ D D E Sbjct: 115 GKALVATPGKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEED--EEDDEDEDEDEDEIEP 172 Query: 1598 ARKEVKYFAESDEEEDDVD 1616 A + A + E+EDD D Sbjct: 173 AAMKAAAAAPASEDEDDED 191 >gi|217330641 IWS1 homolog [Homo sapiens] Length = 819 Score = 62.0 bits (149), Expect = 5e-09 Identities = 119/524 (22%), Positives = 193/524 (36%), Gaps = 97/524 (18%) Query: 1118 ETQNQHDDSSSDSGTPSGPDFNYILNMSLWSL--TKEKVEELIKQRDAKGREVNDLKRKS 1175 E ++++ S + G P G N +L + + EEL +Q+D+ E + Sbjct: 46 ERHSENETSDREDGLPKGHHVTDSENDEPLNLNASDSESEELHRQKDSDS-ESEERAEPP 104 Query: 1176 PSDLWKEDLAAFVEELDKVESQ-------EREDVLAGMSGKAIKGKVGKPKVKKLQLEET 1228 SD ED+ + + E++ E E++L G + + VGK ++EE Sbjct: 105 ASDSENEDVNQHGSDSESEETRKLPGSDSENEELLNGHASDSENEDVGKHPASDSEIEEL 164 Query: 1229 MPSPYGRRIIPEITAMKADASKKLLKKKKGDLDTA-AVKVEFDEEFSGAPVEGAGEEALT 1287 SP D +T A+K + + S P ++ Sbjct: 165 QKSP------------------------ASDSETEDALKPQISDSESEEPPRHQASDSEN 200 Query: 1288 PSVPINKGPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSE-----SDLE 1342 + PKP+ E + P S + R+ SD E++ SD E Sbjct: 201 -----EEPPKPRMSDSES----EELPKPQVSDSESEEPPRHQASDSENEELPKPRISDSE 251 Query: 1343 ETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDDNNDLEELKVKASPITNDGE 1402 +P PR E PK SE ED + D N EEL P +D E Sbjct: 252 SEDP---PRHQASDSENEELPKPRISDSESEDPPRNQASDSEN--EEL---PKPRVSDSE 303 Query: 1403 DEFVPSDGLDKDEYTFSPGKSKATPEK-SLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDS 1461 E P G D T + K PE D++++ S+ S D KF S Sbjct: 304 SE-GPQKGPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHS 362 Query: 1462 NEEDSASVFSPSFGLKQTDKV-PSKTVAAKKGKPSSDTVPKPKRAPKQKKVV-EAVNSDS 1519 ++ + + +K + VA +K SD+ + K + K+ +VV +A +SDS Sbjct: 363 SDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSDS 422 Query: 1520 DSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKPKKTSFDQDSDVD 1579 D+ + GK +K AS SE E K+ S ++ + D Sbjct: 423 DA-------VSDKSGK---REKTIASDSEEEAG---------------KELSDKKNEEKD 457 Query: 1580 IFPSDFPTEPPSLPRTGRARKEV--KYFAESDEEEDDVDFAMFN 1621 +F SD +G + + F ES +EE++ +F FN Sbjct: 458 LFGSD--------SESGNEEENLIADIFGESGDEEEE-EFTGFN 492 Score = 61.6 bits (148), Expect = 6e-09 Identities = 100/452 (22%), Positives = 164/452 (36%), Gaps = 60/452 (13%) Query: 1094 VQRGYESDPVKAWKEAQEKAAEEDETQNQHDDSSSDSGTPSGPDFNYILNMSLWSLTKEK 1153 + R +SD + + E+E NQH S T P + L + Sbjct: 87 LHRQKDSDSESEERAEPPASDSENEDVNQHGSDSESEETRKLPGSDSENEELLNGHASDS 146 Query: 1154 VEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVESQEREDVLAGMSGKAIKG 1213 E + + A E+ +L++ SD ED ++ E E+ + + Sbjct: 147 ENEDVGKHPASDSEIEELQKSPASDSETEDALK-----PQISDSESEEPPRHQASDSENE 201 Query: 1214 KVGKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKKKGDLDTAAVKVEFDEEF 1273 + KP++ + EE +P P +++ +++ + + + ++ D E Sbjct: 202 EPPKPRMSDSESEE-LPKP-------QVSDSESEEPPRHQASDSENEELPKPRIS-DSES 252 Query: 1274 SGAPVEGAG----EEALTPSVPINKGPKPKREKKE-------PGTRV--------RKTPT 1314 P A EE P + ++ P R + P RV +K P Sbjct: 253 EDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQKGPA 312 Query: 1315 SSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEED 1374 S + K+ P SDD+S E+ E+TE + DS + +R K+ SEEE+ Sbjct: 313 SDSETEDASRHKQKPESDDDSDRENKGEDTE---MQNDSFHSDSHMDRKKFHSSDSEEEE 369 Query: 1375 DDAD--DDDDDNNDLEELKV--KASPITNDGEDE--------FVPSDGLDKDEYTFSPGK 1422 D D+D + EE KV + + + +D EDE V SD D D S Sbjct: 370 HKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSDSDAVSDKS 429 Query: 1423 SKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDS--ASVFSPS------- 1473 K EK++ ++ G S +K S NEE++ A +F S Sbjct: 430 GKR--EKTIASDSEEEAGKELSDKKNEEKDLFGSDSESGNEEENLIADIFGESGDEEEEE 487 Query: 1474 -FGLKQTDKVPSKTVAAKKGKPSSDTVPKPKR 1504 G Q D K K SD+ KR Sbjct: 488 FTGFNQEDLEEEKGETQVKEAEDSDSDDNIKR 519 >gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] Length = 1301 Score = 58.9 bits (141), Expect = 4e-08 Identities = 106/502 (21%), Positives = 181/502 (36%), Gaps = 77/502 (15%) Query: 1108 EAQEKAAEEDETQNQHDDSSSDS----GTPSGPDFNYILNMSLWSLTKEKVEELIKQRDA 1163 E + +EDE DSS++S G G + ++ ++ S +KE + K+ D Sbjct: 255 EDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKE-DP 313 Query: 1164 KGREVNDLKRKSPSD---LWKEDLAAFVEELDKVESQEREDVLAGMSGKAIKGKVGKPKV 1220 D KS + + +++ + +E+ K+ +E + V ++ ++ VGK + Sbjct: 314 HNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQD 373 Query: 1221 KKLQLEETMPSPYGRRIIPEI---TAMKADASKKLLKKKKGDLDTAAVKVEFDEEFSGAP 1277 K ++++ PS R I E+ K D + + KG++ T V Sbjct: 374 KGIEIKG--PSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVN--------- 422 Query: 1278 VEGAGEEALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPSA---------KKVKKRN 1328 +EG G+ K EPG +V + T S S K ++ + Sbjct: 423 IEGPGQ------------------KSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDD 464 Query: 1329 PWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDDNNDLE 1388 P S DES D +S R A+ + D D +DDD ++ + Sbjct: 465 PNSSDESNGNDDANSESD----NNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSD 520 Query: 1389 ELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSY 1448 ++ N+G D D D+ GKS ++ S S D + S Sbjct: 521 TNNSDSNGNGNNGND--------DNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSS 572 Query: 1449 SQKSEDDSAKFD--------------SNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKP 1494 S DS D SN DS+ S +D SK+ ++K Sbjct: 573 DSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESD 632 Query: 1495 SSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYN 1554 SSD+ K + + NSDS S+ ++ + +S S N D + Sbjct: 633 SSDSDSKSDSSDSNSS-DSSDNSDS-SDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSS 690 Query: 1555 PGRKTSKTTSKKPKKTSFDQDS 1576 +S ++ S D DS Sbjct: 691 DSSDSSNSSESSDSSDSSDSDS 712 Score = 43.9 bits (102), Expect = 0.001 Identities = 37/212 (17%), Positives = 73/212 (34%), Gaps = 1/212 (0%) Query: 1368 DFSEEEDDDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATP 1427 D S+ D D+ D + ++ + +D D SD D + + S S ++ Sbjct: 562 DSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSD 621 Query: 1428 EKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTV 1487 KS K D + S S + DS+ +S+ DS++ + S +D S + Sbjct: 622 SKSDSSKSESDSSDSDSKSDSSDSNSSDSSD-NSDSSDSSNSSNSSDSSDSSDSSDSSSS 680 Query: 1488 AAKKGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGS 1547 + S + + ++ +SDS ++ + +S S Sbjct: 681 SDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNS 740 Query: 1548 ENEGDYNPGRKTSKTTSKKPKKTSFDQDSDVD 1579 + D + +S ++ S D D Sbjct: 741 SDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSD 772 Score = 43.9 bits (102), Expect = 0.001 Identities = 47/267 (17%), Positives = 91/267 (34%), Gaps = 3/267 (1%) Query: 1315 SSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEED 1374 SS ++ + SD S+SD + DS +++ + D S+ D Sbjct: 794 SSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSS-DSSDGSD 852 Query: 1375 DDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDK 1434 D+ + D +N + S ++D D ++ + + + S S + S + Sbjct: 853 SDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSS 912 Query: 1435 KSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKP 1494 S D N S S++ ++ SN DS+ S ++ S + Sbjct: 913 DSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSN 972 Query: 1495 SSDTVPKPKRAPKQKKVVEAVNSDS--DSEFGIPKKTTTPKGKGRGAKKRKASGSENEGD 1552 SSD+ + + +SDS S ++ + +S S N D Sbjct: 973 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSD 1032 Query: 1553 YNPGRKTSKTTSKKPKKTSFDQDSDVD 1579 + +S ++ S D + D Sbjct: 1033 SSDSSDSSDSSDSSDSSDSSDSSNSSD 1059 Score = 42.4 bits (98), Expect = 0.004 Identities = 53/266 (19%), Positives = 85/266 (31%), Gaps = 16/266 (6%) Query: 1315 SSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEED 1374 SS S+ N +S + SD ++ DS + + D S+ D Sbjct: 815 SSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDS--DSSNRSDSSNSSDSSDSSD 872 Query: 1375 DDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDK 1434 D D++D E S ++D D SD D S + S Sbjct: 873 SSNSSDSSDSSDSNE-----SSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESS 927 Query: 1435 KSQDFGNLFSFPSYSQKSEDDSAKFD-SNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGK 1493 S D N S S S D S D SN DS++ S +D S + + Sbjct: 928 NSSDNSN----SSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSS 983 Query: 1494 PSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDY 1553 SSD+ + ++ NS S+ ++ + +S S + D Sbjct: 984 DSSDSSDSSDSSDSS----DSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDS 1039 Query: 1554 NPGRKTSKTTSKKPKKTSFDQDSDVD 1579 + +S ++ S D D Sbjct: 1040 SDSSDSSDSSDSSDSSNSSDSSDSSD 1065 Score = 41.6 bits (96), Expect = 0.006 Identities = 52/271 (19%), Positives = 93/271 (34%), Gaps = 29/271 (10%) Query: 1314 TSSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEE 1373 + S S+ + S D S S + E ++ DS ++ + S+ + Sbjct: 672 SDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDS----SDSSDSDSSDSSDSSNSNSSDSD 727 Query: 1374 DDDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHD 1433 ++ D D +N + S ++D D S+ D + + S S ++ +D Sbjct: 728 SSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSND 787 Query: 1434 KKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGK 1493 + + S S S S D S DS++ DS++ S +D S + + Sbjct: 788 SSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDS--SNSSDSSDSS 845 Query: 1494 PSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDY 1553 SSD SDSDS + + +S S + D Sbjct: 846 DSSD------------------GSDSDS-----SNRSDSSNSSDSSDSSDSSNSSDSSDS 882 Query: 1554 NPGRKTSKTTSKKPKKTSFDQDSDVDIFPSD 1584 + ++S ++ S D DS SD Sbjct: 883 SDSNESSNSSDSSDSSNSSDSDSSDSSNSSD 913 Score = 41.2 bits (95), Expect = 0.008 Identities = 49/266 (18%), Positives = 87/266 (32%), Gaps = 15/266 (5%) Query: 1315 SSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEED 1374 SS + + SD +S + SD + DS + D S+ D Sbjct: 835 SSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDS----------SNSSDSSDSSD 884 Query: 1375 DDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDK 1434 + + D++D S +++ D S+ D E + S S ++ + D Sbjct: 885 SNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDS 944 Query: 1435 KSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVA-AKKGK 1493 + S S S S + S DSN DS+ + S +D S + + Sbjct: 945 SDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSS 1004 Query: 1494 PSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDY 1553 SSD+ + ++ NS S ++ + +S S N D Sbjct: 1005 DSSDS----SDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1060 Query: 1554 NPGRKTSKTTSKKPKKTSFDQDSDVD 1579 + +S ++ S D D Sbjct: 1061 SDSSDSSDSSDSSDSSDSSDSSESSD 1086 Score = 40.8 bits (94), Expect = 0.011 Identities = 45/249 (18%), Positives = 87/249 (34%), Gaps = 11/249 (4%) Query: 1331 SDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDDNNDLEEL 1390 SD +S + SD ++ DS +++ + + + D+ D D ++ Sbjct: 724 SDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSS 783 Query: 1391 KVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSYSQ 1450 S ++D D SD + + + S S + S S D + S S Sbjct: 784 DSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSD----SSNSS 839 Query: 1451 KSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVPKPKRAPKQKK 1510 S D S D ++ DS++ S +D S SSD+ + + Sbjct: 840 DSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSN-----SSDSSDSSDSNESSNSSDS 894 Query: 1511 VVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKPKKT 1570 + +SDSDS ++ + ++S S + + + +S ++ Sbjct: 895 SDSSNSSDSDSSDS--SNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSN 952 Query: 1571 SFDQDSDVD 1579 S D + D Sbjct: 953 SSDSSNSSD 961 Score = 39.3 bits (90), Expect = 0.031 Identities = 60/346 (17%), Positives = 105/346 (30%), Gaps = 25/346 (7%) Query: 1246 ADASKKLLKKKKGDLDTAAVKVEFDEEFSGAPVEGAGEEALTPSVPINKGPKPKREKKEP 1305 +D+S K + D++ + D S + ++ S N Sbjct: 617 SDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSD 676 Query: 1306 GTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKY 1365 + + SS + + SD S+SD ++ DS ++ Sbjct: 677 SSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSS------DSSNSNSSDSDSSN 730 Query: 1366 TFDFSEEEDD-DADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSK 1424 + D S+ + D+ D D +N + S ++D D SD D + S S Sbjct: 731 SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSN 790 Query: 1425 ATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFD-----------SNEEDSASVFSPS 1473 ++ S S D N S S+ DS+ SN DS+ S Sbjct: 791 SSD--SSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSS 848 Query: 1474 FGLKQTDKVPSKTVAAKKGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPK 1533 G S + + SSD+ + N S+S ++ Sbjct: 849 DGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDS-----NESSNSSDSSDSSNSSDS 903 Query: 1534 GKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKPKKTSFDQDSDVD 1579 + +S S N D + +S ++ S D D Sbjct: 904 DSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSD 949 Score = 38.9 bits (89), Expect = 0.041 Identities = 45/273 (16%), Positives = 90/273 (32%), Gaps = 3/273 (1%) Query: 1314 TSSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEE 1373 +S+ S+ + +S + SD ++ DS +++ + + Sbjct: 728 SSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSND 787 Query: 1374 DDDADDDDDDNNDLEELKVKASPITNDGEDEFVP--SDGLDKDEYTFSPGKSKATPEKSL 1431 ++ D D +N + S ++D D SD + + + S S ++ Sbjct: 788 SSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDS 847 Query: 1432 HDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKK 1491 D D N + S S+ + S+ DS+ S +D S + Sbjct: 848 SDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSD 907 Query: 1492 GKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEG 1551 SSD+ + + + NS+S S+ ++ + +S S N Sbjct: 908 SSNSSDSSDSSNSSDSSESSNSSDNSNS-SDSSNSSDSSDSSDSSNSSDSSNSSDSSNSS 966 Query: 1552 DYNPGRKTSKTTSKKPKKTSFDQDSDVDIFPSD 1584 D + + + S +S DS SD Sbjct: 967 DSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSD 999 Score = 38.9 bits (89), Expect = 0.041 Identities = 60/305 (19%), Positives = 101/305 (33%), Gaps = 30/305 (9%) Query: 1314 TSSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEE 1373 +S+ S+ N +S SD ++ DS + D S+ Sbjct: 1015 SSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS----------SNSSDSSDSS 1064 Query: 1374 DDDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHD 1433 D D D++D + S ++D D SD D + + S S ++ D Sbjct: 1065 DSSDSSDSSDSSDSSD-----SSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSD 1119 Query: 1434 KKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGK 1493 + + S S S S + S DS+E +S S S S + + Sbjct: 1120 SSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDS----------SDSSDSSDSS 1169 Query: 1494 PSSDTVPKPKRAPKQKKVVEAVNSDS--DSEFGIPKKTTTPKGKGRGAKKRKASGSENEG 1551 SSD+ + + +SDS S+ ++ + +S S + Sbjct: 1170 DSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1229 Query: 1552 DYNPGRKTSKTTSKKPKKTSFD--QDSDVDIFPSDFPTEPPSLPRTGRARKEVKYFAESD 1609 D N +S ++ S D SD SD E S ++G ++SD Sbjct: 1230 DSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGS-DSDSD 1288 Query: 1610 EEEDD 1614 E D Sbjct: 1289 SEGSD 1293 Score = 38.5 bits (88), Expect = 0.053 Identities = 49/251 (19%), Positives = 84/251 (33%), Gaps = 23/251 (9%) Query: 1331 SDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDD-----DDDNN 1385 SD SD + DS +++ D S+ E D +D D D N Sbjct: 588 SDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSN- 646 Query: 1386 DLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSF 1445 ++D D SD + + S S ++ S D + + S Sbjct: 647 ------------SSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSD 694 Query: 1446 PSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVPKPKRA 1505 S S +S D S DS+ DS S S +D S + + SSD+ + Sbjct: 695 SSNSSESSDSSDSSDSDSSDS----SDSSNSNSSDSDSSNSSDSSDSSNSSDS-SDSSDS 749 Query: 1506 PKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTSKTTSK 1565 ++ +S + S+ ++ + +S S + D + +S ++ Sbjct: 750 SNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDS 809 Query: 1566 KPKKTSFDQDS 1576 S D DS Sbjct: 810 SDSSDSSDSDS 820 Score = 33.9 bits (76), Expect = 1.3 Identities = 44/263 (16%), Positives = 82/263 (31%), Gaps = 11/263 (4%) Query: 1315 SSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDF----S 1370 SS + + + SD + S+SD ++ DS ++E + + S Sbjct: 879 SSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDS 938 Query: 1371 EEEDDDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKS 1430 D +D D N+ S ++D + SD D S + S Sbjct: 939 SNSSDSSDSSDSSNS-------SDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDS 991 Query: 1431 LHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAK 1490 S D N S S+ ++ SN DS++ S +D S + Sbjct: 992 SDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1051 Query: 1491 KGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENE 1550 +S + ++ +S SE ++ + +S S + Sbjct: 1052 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDS 1111 Query: 1551 GDYNPGRKTSKTTSKKPKKTSFD 1573 D + +S ++ S D Sbjct: 1112 SDSSDSSDSSNSSDSSDSSDSSD 1134 Score = 33.5 bits (75), Expect = 1.7 Identities = 35/213 (16%), Positives = 71/213 (33%), Gaps = 3/213 (1%) Query: 1368 DFSEEEDDDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATP 1427 D S+ + D D++D + ++ ++D D SD + + + S S ++ Sbjct: 975 DSSDSSNSSDSSDSSDSSDSSDSSDSSN--SSDSSDSSDSSDSSNSSDSSNSSDSSNSSD 1032 Query: 1428 EKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNE-EDSASVFSPSFGLKQTDKVPSKT 1486 D + S S S S D S DS++ DS+ S + +D S Sbjct: 1033 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSN 1092 Query: 1487 VAAKKGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASG 1546 + S + ++ NS S+ ++ + ++S Sbjct: 1093 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSD 1152 Query: 1547 SENEGDYNPGRKTSKTTSKKPKKTSFDQDSDVD 1579 S + D + +S ++ S + D Sbjct: 1153 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1185 Score = 33.1 bits (74), Expect = 2.2 Identities = 39/269 (14%), Positives = 83/269 (30%), Gaps = 5/269 (1%) Query: 1316 SGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDD 1375 S S+ + N +S S+ ++ +S +++ + S + + Sbjct: 851 SDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSN 910 Query: 1376 DADDDDDDNNDLEELKVKASPITNDGE-----DEFVPSDGLDKDEYTFSPGKSKATPEKS 1430 +D D N+ +S +N + D SD + + + S S ++ Sbjct: 911 SSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSD 970 Query: 1431 LHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAK 1490 + S D N S S+ + SN DS+ S +D S + Sbjct: 971 SNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNS 1030 Query: 1491 KGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENE 1550 S + ++ NS S+ ++ + ++S S + Sbjct: 1031 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDS 1090 Query: 1551 GDYNPGRKTSKTTSKKPKKTSFDQDSDVD 1579 + + +S ++ S D D Sbjct: 1091 SNSSDSSDSSDSSDSSDSSDSSDSSDSSD 1119 >gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] Length = 1163 Score = 55.1 bits (131), Expect = 6e-07 Identities = 90/397 (22%), Positives = 151/397 (38%), Gaps = 57/397 (14%) Query: 1225 LEETMPSPYGRRIIP---EITAMKADASKKLLKKKKGDLDTAAVKVEFDEEFSGAPVEGA 1281 +++ S GR+ P + T + KK KK A K +E G +E Sbjct: 536 IQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKK--------AEKAAAEEPRGGLKIESE 587 Query: 1282 GEEALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSESDL 1341 L S+P ++ + ++P ++K SS +P+A+K KK S KS + Sbjct: 588 TPVDLASSMPSSRHKAATKGSRKPN--IKKESKSSPRPTAEK-KKYKSTSKSSQKSREII 644 Query: 1342 EETEPVVIPRDSLLRRAAAERPKYTFDF------SEEEDDDADDDDDDNNDLEELKVKAS 1395 E +S +++ PKY S E++D+ + +EE K S Sbjct: 645 ETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEE-KELLS 703 Query: 1396 PITNDGEDEFVPSDGLDKDEYTFSPGK-----------SKATPEKSLHDKKSQDFGNLFS 1444 P++ + +D + +D + T PGK K PEK + + Q + + Sbjct: 704 PLS-EPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSN 762 Query: 1445 FPSYSQKSEDDS----AKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVP 1500 K+EDD+ +K E+ +++ PS +++ SK AAK+ D +P Sbjct: 763 KGKRKHKNEDDNRASESKKPKTEDKNSAGHKPS-----SNRESSKQSAAKE----KDLLP 813 Query: 1501 KPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKG---KGRGAKKRKASGSENEGDYNPGR 1557 P K D +E G K+T + + K + S+N + + Sbjct: 814 SPAGPVPSK--------DPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQK 865 Query: 1558 KTSKTTSKKPKKTSFDQDSDVDIFPSDFPTEPPSLPR 1594 KT TS K+ S P PT S PR Sbjct: 866 KTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPR 902 >gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens] Length = 1758 Score = 54.3 bits (129), Expect = 9e-07 Identities = 100/511 (19%), Positives = 188/511 (36%), Gaps = 48/511 (9%) Query: 1074 KIQGKITIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEDETQNQHDDSSSDSGT- 1132 K K E++ K + + V++ Y D +E+ A++ +N+ D+ + Sbjct: 1056 KAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKR 1115 Query: 1133 ---PSGPDFNYILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVE 1189 G D ++ S ++K +V E++K + E + K + K L+A + Sbjct: 1116 KTEEKGVDKDF--ESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAK 1173 Query: 1190 ELD-------KVESQEREDVLAGMSGK--AIKGKVGKPKVKKLQLEETMPSPYGRRIIPE 1240 ++ K+ S E S K + KV + KVK + + + + Sbjct: 1174 KIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVD 1233 Query: 1241 ITAMKADASKKLLKKKKGDLDTAAVKVEFDEEFSGAPVEGAGEEALTPSVPINKGPKPKR 1300 T+ + + +K + DT ++ EE++ A + + VP +K K Sbjct: 1234 YTSTSSTGGSPV-RKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDF 1292 Query: 1301 EKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAA 1360 E +E + + +S GKP++ S+ E + E +E + Sbjct: 1293 ESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKI------------- 1339 Query: 1361 ERPKYTFDFSEEEDDDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSP 1420 K+T D S E ++ E+ K T D + + + +K Sbjct: 1340 --QKFTKDVSHEIIQHEVKSSKNSASSEKGK------TKDRDYSVLEKENPEK------- 1384 Query: 1421 GKSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTD 1480 K+ PEK + + + GN F S S K S K DS S F+P+ K+TD Sbjct: 1385 RKNSTQPEKESNLDRLNEQGN-FKSLSQSSKEARTSDKHDSTRASSNKDFTPNRD-KKTD 1442 Query: 1481 KVPSKTVAAKKGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAK 1540 + ++K+ ++ + + K + E +PKK T K + Sbjct: 1443 YDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSP 1502 Query: 1541 KRKASGSENEGDYNPGRKTSKTTS--KKPKK 1569 R +++ Y+ R +T S K P K Sbjct: 1503 SRDRKPHDHKATYDTKRPNEETKSVDKNPCK 1533 Score = 38.5 bits (88), Expect = 0.053 Identities = 47/235 (20%), Positives = 89/235 (37%), Gaps = 16/235 (6%) Query: 1120 QNQHDDSSSDSGTPSGPDFNYILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDL 1179 + +H + ++ SG YILN + KE++ I + K + + SDL Sbjct: 1535 REKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDL 1594 Query: 1180 WKE-DLAAFVEELDKVESQE----REDVLAGMSGKAIKGKVGKPKVKKLQLEETMPSPYG 1234 +E D AAF + ++ +S+ +E+ +G K +K K+ + + L + Sbjct: 1595 TRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGIS 1654 Query: 1235 RRIIPEITAMKADASKKLLKKKKGDLDTAAVKVEFDEEFSGAPVEGAGEEALTPSVPINK 1294 R ++ +S + + + + S + ++ K Sbjct: 1655 RN--------QSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKK 1706 Query: 1295 GPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVI 1349 K K+ KK GT V + K KK KK D E + E D ++ + V + Sbjct: 1707 HKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKN---KDKEKEKEKDDQKVKSVTV 1758 Score = 37.0 bits (84), Expect = 0.16 Identities = 34/166 (20%), Positives = 63/166 (37%), Gaps = 13/166 (7%) Query: 1412 DKDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFS 1471 + DE F P +++ E ++ K+ + GN+ S+ +D + D+A+V Sbjct: 1597 ETDEAAFEPDYNESDSESNVSVKEEESSGNI------SKDLKDKIVEKAKESLDTAAVVQ 1650 Query: 1472 PSFGLKQTDKVPSKTVAAKKGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTT 1531 Q+ PS + PS P + + S + K+ Sbjct: 1651 VGISRNQSHSSPSVS-------PSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKK 1703 Query: 1532 PKGKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKPKKTSFDQDSD 1577 K + K +K +G+E E + + K K SKK K +++ D Sbjct: 1704 HKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKD 1749 Score = 33.5 bits (75), Expect = 1.7 Identities = 48/276 (17%), Positives = 102/276 (36%), Gaps = 36/276 (13%) Query: 1299 KREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRA 1358 +R++K TR + +P+ + ++ + K D K D +++ S R Sbjct: 1453 RRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSN------SSPSRDR 1506 Query: 1359 AAERPKYTFDFSEEEDDDADDDDDDNNDLEELKVKASPITNDGEDEFV-----PSDGLDK 1413 K T+D ++ D + D E+ ++A ++ + P ++K Sbjct: 1507 KPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEK 1566 Query: 1414 DEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPS 1473 ++ T KS P+ L S+S + D + E + F P Sbjct: 1567 EQITGQIDKSTVKPKPQL---------------SHSSRLSSDLTR-----ETDEAAFEPD 1606 Query: 1474 FGLKQTDKVPSKTVAAKKGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPK 1533 + ++ S++ + K + SS + K + +K E++++ + + GI + + Sbjct: 1607 Y-----NESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSS 1661 Query: 1534 GKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKPKK 1569 ++ SGS+ + SKK KK Sbjct: 1662 PSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKK 1697 >gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens] Length = 1792 Score = 54.3 bits (129), Expect = 9e-07 Identities = 100/511 (19%), Positives = 188/511 (36%), Gaps = 48/511 (9%) Query: 1074 KIQGKITIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEDETQNQHDDSSSDSGT- 1132 K K E++ K + + V++ Y D +E+ A++ +N+ D+ + Sbjct: 1090 KAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKR 1149 Query: 1133 ---PSGPDFNYILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVE 1189 G D ++ S ++K +V E++K + E + K + K L+A + Sbjct: 1150 KTEEKGVDKDF--ESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAK 1207 Query: 1190 ELD-------KVESQEREDVLAGMSGK--AIKGKVGKPKVKKLQLEETMPSPYGRRIIPE 1240 ++ K+ S E S K + KV + KVK + + + + Sbjct: 1208 KIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVD 1267 Query: 1241 ITAMKADASKKLLKKKKGDLDTAAVKVEFDEEFSGAPVEGAGEEALTPSVPINKGPKPKR 1300 T+ + + +K + DT ++ EE++ A + + VP +K K Sbjct: 1268 YTSTSSTGGSPV-RKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDF 1326 Query: 1301 EKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAA 1360 E +E + + +S GKP++ S+ E + E +E + Sbjct: 1327 ESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKI------------- 1373 Query: 1361 ERPKYTFDFSEEEDDDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSP 1420 K+T D S E ++ E+ K T D + + + +K Sbjct: 1374 --QKFTKDVSHEIIQHEVKSSKNSASSEKGK------TKDRDYSVLEKENPEK------- 1418 Query: 1421 GKSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTD 1480 K+ PEK + + + GN F S S K S K DS S F+P+ K+TD Sbjct: 1419 RKNSTQPEKESNLDRLNEQGN-FKSLSQSSKEARTSDKHDSTRASSNKDFTPNRD-KKTD 1476 Query: 1481 KVPSKTVAAKKGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAK 1540 + ++K+ ++ + + K + E +PKK T K + Sbjct: 1477 YDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSP 1536 Query: 1541 KRKASGSENEGDYNPGRKTSKTTS--KKPKK 1569 R +++ Y+ R +T S K P K Sbjct: 1537 SRDRKPHDHKATYDTKRPNEETKSVDKNPCK 1567 Score = 38.5 bits (88), Expect = 0.053 Identities = 47/235 (20%), Positives = 89/235 (37%), Gaps = 16/235 (6%) Query: 1120 QNQHDDSSSDSGTPSGPDFNYILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDL 1179 + +H + ++ SG YILN + KE++ I + K + + SDL Sbjct: 1569 REKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDL 1628 Query: 1180 WKE-DLAAFVEELDKVESQE----REDVLAGMSGKAIKGKVGKPKVKKLQLEETMPSPYG 1234 +E D AAF + ++ +S+ +E+ +G K +K K+ + + L + Sbjct: 1629 TRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGIS 1688 Query: 1235 RRIIPEITAMKADASKKLLKKKKGDLDTAAVKVEFDEEFSGAPVEGAGEEALTPSVPINK 1294 R ++ +S + + + + S + ++ K Sbjct: 1689 RN--------QSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKK 1740 Query: 1295 GPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVI 1349 K K+ KK GT V + K KK KK D E + E D ++ + V + Sbjct: 1741 HKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKN---KDKEKEKEKDDQKVKSVTV 1792 Score = 37.0 bits (84), Expect = 0.16 Identities = 34/166 (20%), Positives = 63/166 (37%), Gaps = 13/166 (7%) Query: 1412 DKDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFS 1471 + DE F P +++ E ++ K+ + GN+ S+ +D + D+A+V Sbjct: 1631 ETDEAAFEPDYNESDSESNVSVKEEESSGNI------SKDLKDKIVEKAKESLDTAAVVQ 1684 Query: 1472 PSFGLKQTDKVPSKTVAAKKGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTT 1531 Q+ PS + PS P + + S + K+ Sbjct: 1685 VGISRNQSHSSPSVS-------PSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKK 1737 Query: 1532 PKGKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKPKKTSFDQDSD 1577 K + K +K +G+E E + + K K SKK K +++ D Sbjct: 1738 HKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKD 1783 Score = 33.5 bits (75), Expect = 1.7 Identities = 48/276 (17%), Positives = 102/276 (36%), Gaps = 36/276 (13%) Query: 1299 KREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRA 1358 +R++K TR + +P+ + ++ + K D K D +++ S R Sbjct: 1487 RRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSN------SSPSRDR 1540 Query: 1359 AAERPKYTFDFSEEEDDDADDDDDDNNDLEELKVKASPITNDGEDEFV-----PSDGLDK 1413 K T+D ++ D + D E+ ++A ++ + P ++K Sbjct: 1541 KPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEK 1600 Query: 1414 DEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPS 1473 ++ T KS P+ L S+S + D + E + F P Sbjct: 1601 EQITGQIDKSTVKPKPQL---------------SHSSRLSSDLTR-----ETDEAAFEPD 1640 Query: 1474 FGLKQTDKVPSKTVAAKKGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPK 1533 + ++ S++ + K + SS + K + +K E++++ + + GI + + Sbjct: 1641 Y-----NESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSS 1695 Query: 1534 GKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKPKK 1569 ++ SGS+ + SKK KK Sbjct: 1696 PSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKK 1731 >gi|16445033 ACRC protein [Homo sapiens] Length = 691 Score = 54.3 bits (129), Expect = 9e-07 Identities = 59/253 (23%), Positives = 98/253 (38%), Gaps = 38/253 (15%) Query: 1368 DFSEEEDDDADDDDDDNNDLEELKVKASPITNDGEDEF-VPSDGLDKDEYTFSPGKSKAT 1426 D S++ DD+ DD+ D++D+ + K S + +D D+ VP D D E Sbjct: 195 DSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEA 254 Query: 1427 PEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKT 1486 P+ S D ++ D S+D A DS+++ AS S D S Sbjct: 255 PDDSSDDSEAPD-----------DSSDDSEAPDDSSDDSEASDDSSDDSEASDDS--SDD 301 Query: 1487 VAAKKGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGK---------GR 1537 A K VP+ K V NSD D E +P + +G+ Sbjct: 302 SEAPDDKSDDSDVPEDK---SDDSDVPDDNSD-DLEVPVPAEDLCNEGQIASDEEELVEA 357 Query: 1538 GAKKRKASGSENEGDYNPGRKTSKTTSKKPKKTSFDQDSDVDIFPSDFPTE---PPSLPR 1594 A + S++ G+ + G SK S D +++ ++ PTE P + + Sbjct: 358 AAAVSQHDSSDDAGEQDLGENLSKPPS--------DPEANPEVSERKLPTEEEPAPVVEQ 409 Query: 1595 TGRARKEVKYFAE 1607 +G+ + + K E Sbjct: 410 SGKRKSKTKTIVE 422 Score = 38.1 bits (87), Expect = 0.070 Identities = 54/249 (21%), Positives = 85/249 (34%), Gaps = 32/249 (12%) Query: 1376 DADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKK 1435 D D+DDD+ NDLE P N + E P D D E P+ + D + Sbjct: 125 DDDNDDDNGNDLE------VPDDNSDDSE-APDDNSDDSEAPDDNSDDSEAPDDNSDDSE 177 Query: 1436 SQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSA---SVFSPSFGLKQTDKVPSKTVAAKKG 1492 + D + DDS D N +DS+ S S +D K+ + Sbjct: 178 APD------------DNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVP 225 Query: 1493 KPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGD 1552 SSD P + + + + DS++ + P ++ S ++E Sbjct: 226 DDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAS 285 Query: 1553 YNPGRKTSKTTSKKPKKTSFDQDSDVDIFPSDFPTEPPSLPRTGRARKEVKYFAE----- 1607 + + + + D SD P D ++ +P EV AE Sbjct: 286 DDSSDDSEASDDSSDDSEAPDDKSDDSDVPED-KSDDSDVPDDNSDDLEVPVPAEDLCNE 344 Query: 1608 ----SDEEE 1612 SDEEE Sbjct: 345 GQIASDEEE 353 >gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sapiens] Length = 699 Score = 53.9 bits (128), Expect = 1e-06 Identities = 72/327 (22%), Positives = 112/327 (34%), Gaps = 34/327 (10%) Query: 1308 RVRKTPTSSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTF 1367 +V + + P AKK KK+ SD E SE + E P +R K Sbjct: 62 KVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAA 121 Query: 1368 DFSEEEDDDADDDDDDNNDLEELKV-----------KASPITNDGEDEFVPSDGLDKDEY 1416 SE + DDDD D ++ V KA P D S D+ Sbjct: 122 KASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPK 181 Query: 1417 TFSP--------GKSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSAS 1468 P ++KA P+ + K + S S S S D DS EE +A+ Sbjct: 182 NQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSD----DSEEEKAAA 237 Query: 1469 VFSPSFGLKQ-TDKVPSKTVAAKKGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPK 1527 + KQ K P K K SS +QKK ++ S +P Sbjct: 238 TPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSS---VPP 294 Query: 1528 KTTTPKGKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKPKKTSFDQDSDVDIFPSDFPT 1587 + P K G + K + + + P + ++ + + ++ S T Sbjct: 295 PSAPPPKKSLGTQPPKKAVEKQQ----PVESSEDSSDESDSSSEEEKKPPTKAVVSKATT 350 Query: 1588 EPPSLPRTGRARKEVKYFAESDEEEDD 1614 +PP + + + ++SD EDD Sbjct: 351 KPPPAKKAAESSSD---SSDSDSSEDD 374 Score = 52.4 bits (124), Expect = 4e-06 Identities = 114/552 (20%), Positives = 192/552 (34%), Gaps = 91/552 (16%) Query: 1099 ESDPVKAWKEAQEKAAEEDETQNQHDDSSSDSGTPSGPDFNYILNMSLWSLTKEKVEELI 1158 + PV+ + Q KAA+ + + DS SDS + P N K K+ + Sbjct: 142 KKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQ----------KPKITPVT 191 Query: 1159 KQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVESQEREDVLAGMSGKAIKGKVGKP 1218 + K R +P + ++ S + E+ A + K K K Sbjct: 192 VKAQTKAPPKP--ARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPK--KQ 247 Query: 1219 KVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKKKG---------------DLDTA 1263 V K ++ + ++ + + KK +K K G L T Sbjct: 248 VVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQ 307 Query: 1264 AVKVEFDEEFSGAPVEGAGEEALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPSAKK 1323 K +++ PVE + + + ++ E+K+P T+ + ++ P AKK Sbjct: 308 PPKKAVEKQ---QPVESSEDSS-------DESDSSSEEEKKPPTKAVVSKATTKPPPAKK 357 Query: 1324 VKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAA---------AERPKYTFDFSEE-- 1372 + + S D SE D ++P ++S + A A PK ++ Sbjct: 358 AAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLL 417 Query: 1373 -EDDDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSL 1431 D+ +++++ EE K K T K KAT + +L Sbjct: 418 TRKADSSSSEEESSSSEEEKTKKMVATT----------------------KPKATAKAAL 455 Query: 1432 HDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKV-----PSKT 1486 Q P S+ S DS S EE+ + S S K+ KV PSK Sbjct: 456 SLPAKQ-------APQGSRDSSSDSDSSSSEEEEEKT--SKSAVKKKPQKVAGGAAPSKP 506 Query: 1487 VAAKKGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASG 1546 +AKKGK S + ++++ E + PK T + K K S Sbjct: 507 ASAKKGKAESSNSSSSDDSSEEEE--EKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSE 564 Query: 1547 SENEGDYNPGRKTSKTTS-KKPKKTSFDQDSDVDIFPSDFPTEPPSLPRTGRARKEVKY- 1604 E E SK+ S KK K+ ++++ P + P+ + K Sbjct: 565 EEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTPNTFPKRKKGEKRASSP 624 Query: 1605 FAESDEEEDDVD 1616 F EEE +VD Sbjct: 625 FRRVREEEIEVD 636 Score = 33.1 bits (74), Expect = 2.2 Identities = 61/297 (20%), Positives = 106/297 (35%), Gaps = 22/297 (7%) Query: 1107 KEAQEKAAEEDETQNQHDDSSSDSGTPSGPDFNYILNMSLWSLTKEK--VEELIKQRDAK 1164 K K A E + + DSS D PS P + + ++T + V+ + Sbjct: 351 KPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPV 410 Query: 1165 GREVNDLKRKSPSDLWKEDLAAFVEELDK---VESQEREDVLAGMSGKAIKGKVGK---- 1217 G L RK+ S +E+ ++ EE K ++ + A +S A + G Sbjct: 411 GGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSS 470 Query: 1218 --PKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKK-------KGDLDTAAVKVE 1268 + EE S + P+ A A SK KK D ++ + E Sbjct: 471 SDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEE 530 Query: 1269 FDEEFSGAPVEGAGEEALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRN 1328 + G+P A + T ++ G K ++E + + S S KK K+ Sbjct: 531 EKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNE 590 Query: 1329 PWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDDNN 1385 + E+ ++ P P+ R+ +R F EE+ + D DN+ Sbjct: 591 AAKEAETPQAKKIKLQTPNTFPK----RKKGEKRASSPFRRVREEEIEVDSRVADNS 643 >gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] Length = 1020 Score = 53.9 bits (128), Expect = 1e-06 Identities = 115/585 (19%), Positives = 207/585 (35%), Gaps = 80/585 (13%) Query: 1059 AESTKLNNQARFILEKIQGKITIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEDE 1118 +E+ K+N A + Q +IT R L R E + +K+ K++ E+ E E Sbjct: 301 SEAAKVNTDA---MRSAQEEITEYRRQ-------LQARTTELEALKSTKDSLERQRSELE 350 Query: 1119 TQNQHDDSSSDSGTPSGPDFNYILNMSLWSLTKEKVEELIKQRDAKGREVN---DLKRKS 1175 ++Q D +S +E I+Q DA+ R + + Sbjct: 351 DRHQADIAS--------------------------YQEAIQQLDAELRNTKWEMAAQLRE 384 Query: 1176 PSDLWKEDLAAFVEELDKVESQEREDVLAGMSGKAIKGKVGKPKVKKLQLEETMPSPYGR 1235 DL +A +E + E E+ G G PK+ + + S Sbjct: 385 YQDLLNVKMALDIEIAAYRKLLEGEECRIGFGPIPFSLPEGLPKIPSVSTHIKVKSEEKI 444 Query: 1236 RIIPE-----ITAMKADASKKLLKKKKGDLDTAAVKVEFDEEFSGAPVEGAGEEALTPSV 1290 +++ + + + ++ ++ + + A + E EE G E G E T S Sbjct: 445 KVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSP 504 Query: 1291 PINKGPKPKREKKEPGTRVRKTPTSSGKP---------------SAKKVKKRNPWSDDES 1335 P + P++E K P K+P + P AK K S E+ Sbjct: 505 PAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEA 564 Query: 1336 KSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDDNNDLEELKVKAS 1395 KS E P + + A E K + E + ++ + E S Sbjct: 565 KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAE----AKS 620 Query: 1396 PITNDGEDEFVPSDGLDKDEYTFSPGKSKA-TPEKSLH-DKKSQDFGNLFSFPSYSQKSE 1453 P+ + + P++ + E SP K +A +PEK+ +K+ P ++ Sbjct: 621 PVKEEAKS---PAE-VKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKS 676 Query: 1454 DDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVPKPKRAP--KQKKV 1511 + AK E + + S +K+ K P K + K + S P+ ++P ++ K Sbjct: 677 PEKAKSPVKAEAKSPEKAKS-PVKEEAKSPEKAKSPVKEEAKS---PEKAKSPVKEEAKT 732 Query: 1512 VEAVNSDSDSEFGIPKKTTTP-KGKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKPKKT 1570 E S E P+K +P K K K +A E +P K + K+ Sbjct: 733 PEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEE 792 Query: 1571 SFDQDSDVDIFPSDFPTEPPSLPRTGRARKEVKYFAESDEEEDDV 1615 + D +P+ ++EVK + +E+ +V Sbjct: 793 VKSPEKAKSPLKEDAKAPEKEIPK----KEEVKSPVKEEEKPQEV 833 Score = 53.9 bits (128), Expect = 1e-06 Identities = 102/480 (21%), Positives = 178/480 (37%), Gaps = 73/480 (15%) Query: 1102 PVKAWKEAQEKAAEEDETQNQHDDSSSDSGTPSGPDFNYILNMSLWSLTKEKVEELIKQR 1161 P KA +E+A E ++ + + P+ S TKE+ + K + Sbjct: 601 PEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPE-------KAKSPTKEEAKSPEKAK 653 Query: 1162 DAKGREVNDL-KRKSP-------SDLWKEDLAAFVEELDKVESQEREDVLAGMSGKA-IK 1212 + E K KSP + K + A + +K +S +E+ + K+ +K Sbjct: 654 SPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVK 713 Query: 1213 GKVGKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKKKGDLDTAAVKVEFDEE 1272 + P+ K ++E +P + + A + +K K K D+ + K EE Sbjct: 714 EEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEE 773 Query: 1273 FSGAPVEGAGEEALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSD 1332 + +P + E+A +P + + K + K P K P K KK + ++P + Sbjct: 774 -ARSPADKFPEKAKSP---VKEEVKSPEKAKSPLKEDAKAPE---KEIPKKEEVKSPVKE 826 Query: 1333 DESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDDNNDLEELKV 1392 +E E ++E P A PK T + + + ++A + +EE K Sbjct: 827 EEKPQEVKVKE------PPKKAEEEKAPATPK-TEEKKDSKKEEAPKKEAPKPKVEEKKE 879 Query: 1393 KASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSYSQKS 1452 A + + E + DK K TPEK P+ + Sbjct: 880 PAVEKPKESKVEAKKEEAEDK--------KKVPTPEKEA--------------PAKVEVK 917 Query: 1453 ED----DSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVPKPKRAPKQ 1508 ED + + E D A PS K +K K A +K + KP+ PK Sbjct: 918 EDAKPKEKTEVAKKEPDDAKAKEPS---KPAEK---KEAAPEKKDTKEEKAKKPEEKPK- 970 Query: 1509 KKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKPK 1568 EA + D + K+ + PK A+K + S S ++ D P K ++ + K K Sbjct: 971 ---TEAKAKEDDKT--LSKEPSKPK-----AEKAEKSSSTDQKDSKPPEKATEDKAAKGK 1020 Score = 43.5 bits (101), Expect = 0.002 Identities = 114/585 (19%), Positives = 200/585 (34%), Gaps = 80/585 (13%) Query: 1063 KLNNQARFILEKIQGKITIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEDETQNQ 1122 K+ + + I K + KI + +S+K+ + ++ ++ E+ + E +EK A+E+E + + Sbjct: 428 KIPSVSTHIKVKSEEKIKVVEKSEKETV-IVEEQTEETQVTEEVTEEEEKEAKEEEGKEE 486 Query: 1123 HDDSSSDSGTPSGPDFNYILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKE 1182 ++ E EE K A+ + + KSP KE Sbjct: 487 EGGEEEEA---------------------EGGEEETKSPPAEEAASPEKEAKSPV---KE 522 Query: 1183 DLAAFVEELDKVESQEREDVLAGMSGKAIKGKVGKPKVKKLQLEETMPSPYGRRIIPEIT 1242 + + E +S E+E+ + +V P+ K +E SP + PE Sbjct: 523 EAKSPAE----AKSPEKEEAKS-------PAEVKSPEKAKSPAKEEAKSPPEAKS-PEKE 570 Query: 1243 AMKADASKKLLKKKKGDLDTAAVKVEFDE--EFSGAPVEGAGEEALTPSVPINKGPKPKR 1300 K+ A K +K K A + E + +PV+ + P+ + K Sbjct: 571 EAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPA 630 Query: 1301 EKKEPGTRVRKTPTSSGKPSAKKVK---KRNPWSDDESKSESDLEETEPVVIPRDSLLRR 1357 E K P K+PT S +K K K S +++KS E P S ++ Sbjct: 631 EVKSP--EKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPE--KAKSPVKA 686 Query: 1358 AAAERPKYTFDFSEEEDDDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKD--- 1414 A K EE + + + SP+ + + + ++ Sbjct: 687 EAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKS 746 Query: 1415 -EYTFSPGKSKA---------TPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEE 1464 E SP K+K TP K + F P + + AK E+ Sbjct: 747 PEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKED 806 Query: 1465 DSA---------SVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVPKPKR--------APK 1507 A V SP ++ +V K K + + PK + APK Sbjct: 807 AKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPK 866 Query: 1508 QKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKP 1567 ++ V + PK++ K K+K E E P + K +K Sbjct: 867 KEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEA---PAKVEVKEDAKPK 923 Query: 1568 KKTSFDQDSDVDIFPSDFPTEPPSLPRTGRARKEVKYFAESDEEE 1612 +KT + D + P++P +K+ K EE Sbjct: 924 EKTEVAKKEPDDAKAKE-PSKPAEKKEAAPEKKDTKEEKAKKPEE 967 >gi|59814411 hypothetical protein LOC253725 [Homo sapiens] Length = 1318 Score = 52.4 bits (124), Expect = 4e-06 Identities = 75/294 (25%), Positives = 114/294 (38%), Gaps = 55/294 (18%) Query: 1373 EDDDADDDDD-----DNNDLEELKVKASP-ITNDGEDEFVPSDGLDKDEYTFSP-GKSKA 1425 +DDD DDDDD + + KV+++ I D E + + E T S ++KA Sbjct: 452 DDDDGDDDDDFFSAPHSKPSKTRKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKA 511 Query: 1426 TPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSP--SFGLKQTDKVP 1483 EK + S++ PS K++ S+EEDS +FS + LK +P Sbjct: 512 RAEKKVTLSYSKNLK-----PSSETKTQKG---LFSDEEDSEDLFSSQSASNLKGASLLP 563 Query: 1484 SKT-------------------VAAKKGKPS--SDTVPKPKRAPKQKKVVEAVNSDSDSE 1522 K AAKK S + K K + KK A+ SD E Sbjct: 564 GKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQREEKAKASELSKKKASALLFSSDEE 623 Query: 1523 FGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTS--------------KTTSKKPK 1568 + IP T R + + SG+ + +KTS K + KK + Sbjct: 624 WNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDKEDDLFAIAKDSQKKTQ 683 Query: 1569 KTSFDQDSDVDIFPSDFPTEPPSLPRTGRARK---EVKYFAESDEEEDDVDFAM 1619 + S + DVD S F + P S+P + ++ E SDEEE + + Sbjct: 684 RVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGV 737 Score = 40.8 bits (94), Expect = 0.011 Identities = 73/326 (22%), Positives = 119/326 (36%), Gaps = 53/326 (16%) Query: 1333 DESKSESDLEETEPVVIPRDSLLRRAAAE-----RPKYTFDFSEEEDDDADDDDDDNNDL 1387 D K E D+E+ E P+ S A E + EE + L Sbjct: 264 DSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAMGRVDEEPTTLPSGEAKPRKTL 323 Query: 1388 EELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPS 1447 +E K + +P ++ ++ F P D+D F G + K L D + ++ +LF Sbjct: 324 KEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEE-SDLF---- 378 Query: 1448 YSQKSEDDSAKFDSNEEDSAS-------VFSPSFGLKQTDKVPSKTVAAKK--GKPSSDT 1498 ++ S+D A EE S+S + S L TD + +V + K KP T Sbjct: 379 -TEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSLKEPQKPEQPT 437 Query: 1499 VPKPKRAPKQKKVVEAVNSDSDSEF-----GIPKKTTTPKG--------KGRGAKKRKAS 1545 K P + + + D D +F P KT + +G K++ + Sbjct: 438 PRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTADIFGDEEGDLFKEKAVA 497 Query: 1546 GSE---NEGDYNPGRKTSKTT------------SKKPKKTSFDQDSDVDIFPSDFPTE-- 1588 E ++ D N R K T +K K D++ D+F S + Sbjct: 498 SPEATVSQTDENKARAEKKVTLSYSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASNLK 557 Query: 1589 -PPSLPRTGRARKEVKYFAESDEEED 1613 LP G+ V F + DEE++ Sbjct: 558 GASLLP--GKLPTSVSLFDDEDEEDN 581 >gi|55741677 SET domain containing 1A [Homo sapiens] Length = 1707 Score = 52.0 bits (123), Expect = 5e-06 Identities = 73/330 (22%), Positives = 112/330 (33%), Gaps = 64/330 (19%) Query: 1279 EGAGEEALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSE 1338 E + E+ PS P + ++KE G G+P K K+ DE + + Sbjct: 905 EASEEKRPRPSTPAEEDEDDPEQEKEAG--------EPGRPGTKPPKR------DEERGK 950 Query: 1339 SDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDDNNDLEELKVKASPIT 1398 + + R S + E ++E+DD +D++D++ + K Sbjct: 951 TQGKH-------RKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEV 1003 Query: 1399 NDGEDEFVPSDGLDK-DEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSA 1457 +DGEDE SD K Y S G++ +T + S + S S S S +S+ Sbjct: 1004 SDGEDE--ESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESS 1061 Query: 1458 KFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVPKPKRAPKQKKVVEAVNS 1517 D EE+ + A P VP P AP + V E V Sbjct: 1062 SEDEEEEE-------------------RPAALPSASPPPREVPVPTPAPVEVPVPERV-- 1100 Query: 1518 DSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKPKKTSFDQDSD 1577 G P TP + + R A +E P R Sbjct: 1101 -----AGSP---VTPLPEQEASPARPAGPTEESPPSAPLRPPEPPAGPPAPAPR------ 1146 Query: 1578 VDIFPSDFPTEP-PSLPRTGRARKEVKYFA 1606 P + P+ P P LP + RK V + A Sbjct: 1147 ----PDERPSSPIPLLPPPKKRRKTVSFSA 1172 >gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 [Homo sapiens] Length = 916 Score = 51.2 bits (121), Expect = 8e-06 Identities = 104/508 (20%), Positives = 193/508 (37%), Gaps = 52/508 (10%) Query: 1084 RSKKDLI----QMLVQRGYESDPVKAWKEAQEKAAEEDETQNQHDDSSSDSGTPSGPDFN 1139 RS K+ I + L + E + V+ KE+ E+ + E ++ HD SS Sbjct: 311 RSAKEEIAEYRRQLQSKSIELESVRGTKESLERQLSDIEERHNHDLSSYQDTIQQ---LE 367 Query: 1140 YILNMSLWSLTKE--KVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVESQ 1197 L + W + + + ++L+ + A E+ ++ + + + F + Sbjct: 368 NELRGTKWEMARHLREYQDLLNVKMALDIEIAAYRKLLEGE--ETRFSTFAGSITGPLYT 425 Query: 1198 EREDVLAGMSGKAIKGKVGKPKVKKLQ------LEETMPSPYGRRIIPEITAMKADASKK 1251 R + +S K K KV PK+K +EET + +TA+ + + Sbjct: 426 HRPPIT--ISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVS 483 Query: 1252 LLKKKKGDLDTAAVKVEFDEEFSGAPVEGAGEEALTPSVPINKGPKPKREKKEP------ 1305 + ++KK + + E +EE A + + +A P V +G K + E +E Sbjct: 484 MKEEKKEAAEEKEEEPEAEEEEVAA--KKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDE 541 Query: 1306 GTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKY 1365 G + + + K+ + E+++E++ EE E + A + + Sbjct: 542 GAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEEL 601 Query: 1366 TFDFSEEEDDDADDDDDDNNDLEELK--VKASPITNDGEDEFV--PSDGLDKDEYTFSPG 1421 D E+ + A + E+ K V SP+ G+ P + K SP Sbjct: 602 VADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPV 661 Query: 1422 KSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDK 1481 + K S + + + P KS+ + K + EE+ K+ + Sbjct: 662 EEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEE----------KEVKE 711 Query: 1482 VPSKTVAAKKGKPSSDTVPKPKRAP---KQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRG 1538 P + KK + D VP+ K+A K++ V E V + + K+T +GK Sbjct: 712 APKEEKVEKKEEKPKD-VPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKE-EGKPLQ 769 Query: 1539 AKKRK-----ASGSENEGDYNPGRKTSK 1561 +K K GSE EG + G K S+ Sbjct: 770 QEKEKEKAGGEGGSEEEGS-DKGAKGSR 796 Score = 42.4 bits (98), Expect = 0.004 Identities = 62/263 (23%), Positives = 106/263 (40%), Gaps = 28/263 (10%) Query: 1082 ENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEDETQNQHDDSSSDSGTPSGPDFNYI 1141 E +KK ++ E + K +E QE+ EEDE + SD G + Sbjct: 505 EVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDE------GAKSDQAEEGGSEKEGS 558 Query: 1142 LNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVESQERED 1201 + + E + +A+ +E ++ KS KE+L A KVE E+ Sbjct: 559 SEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADA----KVEKPEKAK 614 Query: 1202 VLAGMSGKAIKGKVGKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKK-KGDL 1260 S K GK V K +EE SP + + E K+ K +++K K + Sbjct: 615 SPVPKSPVEEK---GKSPVPKSPVEEKGKSPVPKSPVEE--KGKSPVPKSPVEEKGKSPV 669 Query: 1261 DTAAVKVEFDEEFSGAPVEGAGEEALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPS 1320 + V+ + +PVE A +A + KG + + E+KE V++ P Sbjct: 670 SKSPVEEKAKSPVPKSPVEEAKSKA-----EVGKGEQKEEEEKE----VKEAPKEEKVEK 720 Query: 1321 AKKVKKRNPWSDDESKSESDLEE 1343 ++ K P ++ K+ES ++E Sbjct: 721 KEEKPKDVP---EKKKAESPVKE 740 Score = 32.7 bits (73), Expect = 2.9 Identities = 60/305 (19%), Positives = 107/305 (35%), Gaps = 26/305 (8%) Query: 1318 KPSAKKVKKRNPWSDD---ESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEED 1374 K A K+K ++ + ++ E+K E + E E + L + E K + EEE Sbjct: 440 KVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEP 499 Query: 1375 DDADDDDDDNNDLEELKVKASPI------TNDGEDEFVPSDGLDKDEYTFSPGKSKATPE 1428 + + EE+ K SP+ + E E +G +++E KS E Sbjct: 500 EAEE---------EEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEE 550 Query: 1429 KSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVA 1488 +K+ ++E + + ++ EE S K+ +K Sbjct: 551 GG-SEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEK 609 Query: 1489 AKKGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSE 1548 +K K VPK K K V + + +PK KGK K + Sbjct: 610 PEKAK---SPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGK 666 Query: 1549 NEGDYNPGRKTSKTTSKKPKKTSFDQDSDVDIFPSDFPTEPPSLPRTGRARKEVKYFAES 1608 + +P + +K S PK + S ++ + E A KE K + Sbjct: 667 SPVSKSPVEEKAK--SPVPKSPVEEAKSKAEVGKGEQKEEEEK--EVKEAPKEEKVEKKE 722 Query: 1609 DEEED 1613 ++ +D Sbjct: 723 EKPKD 727 >gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapiens] Length = 674 Score = 50.4 bits (119), Expect = 1e-05 Identities = 62/267 (23%), Positives = 103/267 (38%), Gaps = 32/267 (11%) Query: 1086 KKDLIQMLVQRGY--ESDPVKAWKEAQEKAAEEDETQNQHDDSSSDSGTPSGPDFNYILN 1143 KK L + GY E V ++A EK EE+ + +S D P + + Sbjct: 153 KKKLAEKKASIGYTYEDSTVAEVEKAAEKPEEEESAAEEESNSDEDEVIP-----DIDVE 207 Query: 1144 MSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVESQEREDVL 1203 + + L +E+V +L KQ G D R D KE+ E + ++ E E + Sbjct: 208 VDVDELNQEQVADLNKQATTYGMADGDFVRMLRKD--KEE----AEAIKHAKALEEEKAM 261 Query: 1204 AGMSGKAIKGKVGKPKVKKLQLEETMPSPYGRRIIPEITAMK---ADASKKLLKKKKGDL 1260 SG+ + + + + K+L+ + P Y RR P K +++S + + + Sbjct: 262 --YSGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPT 319 Query: 1261 DTAAVKVEFDEEFSGAPVEGAGEEALT----------PSVPINKGPKPKREKKEPGTRVR 1310 K+ F F G+ E A A P+ P GP P R + R Sbjct: 320 PGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRN----ASARR 375 Query: 1311 KTPTSSGKPSAKKVKKRNPWSDDESKS 1337 ++ +SS SA + S S+S Sbjct: 376 RSSSSSSSSSASRTSSSRSSSRSSSRS 402 Score = 32.3 bits (72), Expect = 3.8 Identities = 50/242 (20%), Positives = 87/242 (35%), Gaps = 49/242 (20%) Query: 1359 AAERPKYTFDFSEEEDDDADD----DDDDNNDLEELKVKASPITNDGEDEFVPSDG---- 1410 AAE+P+ +EEE + +D D D D++EL + N + +DG Sbjct: 178 AAEKPEEEESAAEEESNSDEDEVIPDIDVEVDVDELNQEQVADLNKQATTYGMADGDFVR 237 Query: 1411 ---LDKDEYTFSPGKSKATPEKSLHD-----KKSQDF------GNLFSFPSYSQKSEDDS 1456 DK+E EK+++ ++ ++F G S PSY+++ Sbjct: 238 MLRKDKEEAEAIKHAKALEEEKAMYSGRRSRRQRREFREKRLRGRKISPPSYARRDSPTY 297 Query: 1457 AKFDSNEEDSAS-----------------VFSPSFGLKQTDKVPSKTVAAKK----GKPS 1495 + + +S+S F SFG + + AA GKP Sbjct: 298 DPYKRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPP 357 Query: 1496 SDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNP 1555 + P+P + S S S +T++ + R + + + G G Y Sbjct: 358 AP--PQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGG----GYYRS 411 Query: 1556 GR 1557 GR Sbjct: 412 GR 413 >gi|48255931 hepatoma-derived growth factor-related protein 2 isoform 1 [Homo sapiens] Length = 671 Score = 49.7 bits (117), Expect = 2e-05 Identities = 77/324 (23%), Positives = 120/324 (37%), Gaps = 67/324 (20%) Query: 1317 GKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDD 1376 GKP+ +K W + S P V DS E P + + + D Sbjct: 69 GKPNKRKGFNEGLWEIQNNPHAS--YSAPPPVSSSDS-------EAP----EANPADGSD 115 Query: 1377 ADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKS 1436 AD+DD+D + V A+ ++ E + D D+ + + G + TP + K Sbjct: 116 ADEDDEDRGVMAVTAVTATAASDRMESD------SDSDKSSDNSGLKRKTPALKMSVSKR 169 Query: 1437 QDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSS 1496 + S+ D A +EE+++ S S D P K A Sbjct: 170 ----------ARKASSDLDQASVSPSEEENSESSSESEKTSDQDFTPEKKAA-------- 211 Query: 1497 DTVPKPKRAP----KQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGD 1552 V P+R P K+KK A SDSDS+ P R A +S S ++ D Sbjct: 212 --VRAPRRGPLGGRKKKKAPSA--SDSDSKADSDGAKPEPVAMARSASSSSSSSSSSDSD 267 Query: 1553 YN-----PGRKTS-----KTTSKKPK------KTSFDQDSDVDIFPSDFPTEPPSLPRTG 1596 + GRK + K +KPK +S D DSD S++ + R Sbjct: 268 VSVKKPPRGRKPAEKPLPKPRGRKPKPERPPSSSSSDSDSDEVDRISEWKRRDEARRREL 327 Query: 1597 RARK------EVKYFAESDEEEDD 1614 AR+ E++ E ++EE + Sbjct: 328 EARRRREQEEELRRLREQEKEEKE 351 Score = 41.6 bits (96), Expect = 0.006 Identities = 75/344 (21%), Positives = 124/344 (36%), Gaps = 99/344 (28%) Query: 1243 AMKADASKKLLKKKKGDLDTAAVKVEFDEEF-SGAPVEGAGEEALTPSVPINKGPKPKRE 1301 A+K SK+ +K DLD A+V +E S + E ++ TP E Sbjct: 161 ALKMSVSKRA-RKASSDLDQASVSPSEEENSESSSESEKTSDQDFTP------------E 207 Query: 1302 KKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAE 1361 KK R+ P +K KK SD +SK++SD + EPV + R + Sbjct: 208 KKAAVRAPRRGPLGG-----RKKKKAPSASDSDSKADSDGAKPEPVAMARSA-------- 254 Query: 1362 RPKYTFDFSEEEDDDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPG 1421 S + D D + VK P ++ +P P Sbjct: 255 --------SSSSSSSSSSDSD-------VSVKKPPRGRKPAEKPLP-----------KPR 288 Query: 1422 KSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDK 1481 K PE+ P S S+ DS + D E K+ D+ Sbjct: 289 GRKPKPER----------------PPSSSSSDSDSDEVDRISE-----------WKRRDE 321 Query: 1482 VPSKTVAAKKGKPSSDTVPKPKRAPKQKKVVEAVNSD-SDSEFGI-------------PK 1527 + + A++ + + + + + K++K +D ++E G P Sbjct: 322 ARRRELEARRRREQEEELRRLREQEKEEKERRRERADRGEAERGSGGSSGDELREDDEPV 381 Query: 1528 KTTTPKGKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKPKKTS 1571 K KG+GRG +S SE E + + +K ++KKP+ +S Sbjct: 382 KKRGRKGRGRGPP--SSSDSEPEAEL---EREAKKSAKKPQSSS 420 >gi|14249158 hepatoma-derived growth factor-related protein 2 isoform 2 [Homo sapiens] Length = 670 Score = 49.7 bits (117), Expect = 2e-05 Identities = 77/324 (23%), Positives = 120/324 (37%), Gaps = 67/324 (20%) Query: 1317 GKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDD 1376 GKP+ +K W + S P V DS E P + + + D Sbjct: 69 GKPNKRKGFNEGLWEIQNNPHAS--YSAPPPVSSSDS-------EAP----EANPADGSD 115 Query: 1377 ADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKS 1436 AD+DD+D + V A+ ++ E + D D+ + + G + TP + K Sbjct: 116 ADEDDEDRGVMAVTAVTATAASDRMESD------SDSDKSSDNSGLKRKTPALKMSVSKR 169 Query: 1437 QDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSS 1496 + S+ D A +EE+++ S S D P K A Sbjct: 170 ----------ARKASSDLDQASVSPSEEENSESSSESEKTSDQDFTPEKKAA-------- 211 Query: 1497 DTVPKPKRAP----KQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGD 1552 V P+R P K+KK A SDSDS+ P R A +S S ++ D Sbjct: 212 --VRAPRRGPLGGRKKKKAPSA--SDSDSKADSDGAKPEPVAMARSASSSSSSSSSSDSD 267 Query: 1553 YN-----PGRKTS-----KTTSKKPK------KTSFDQDSDVDIFPSDFPTEPPSLPRTG 1596 + GRK + K +KPK +S D DSD S++ + R Sbjct: 268 VSVKKPPRGRKPAEKPLPKPRGRKPKPERPPSSSSSDSDSDEVDRISEWKRRDEARRREL 327 Query: 1597 RARK------EVKYFAESDEEEDD 1614 AR+ E++ E ++EE + Sbjct: 328 EARRRREQEEELRRLREQEKEEKE 351 Score = 41.6 bits (96), Expect = 0.006 Identities = 75/344 (21%), Positives = 124/344 (36%), Gaps = 99/344 (28%) Query: 1243 AMKADASKKLLKKKKGDLDTAAVKVEFDEEF-SGAPVEGAGEEALTPSVPINKGPKPKRE 1301 A+K SK+ +K DLD A+V +E S + E ++ TP E Sbjct: 161 ALKMSVSKRA-RKASSDLDQASVSPSEEENSESSSESEKTSDQDFTP------------E 207 Query: 1302 KKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAE 1361 KK R+ P +K KK SD +SK++SD + EPV + R + Sbjct: 208 KKAAVRAPRRGPLGG-----RKKKKAPSASDSDSKADSDGAKPEPVAMARSA-------- 254 Query: 1362 RPKYTFDFSEEEDDDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPG 1421 S + D D + VK P ++ +P P Sbjct: 255 --------SSSSSSSSSSDSD-------VSVKKPPRGRKPAEKPLP-----------KPR 288 Query: 1422 KSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDK 1481 K PE+ P S S+ DS + D E K+ D+ Sbjct: 289 GRKPKPER----------------PPSSSSSDSDSDEVDRISE-----------WKRRDE 321 Query: 1482 VPSKTVAAKKGKPSSDTVPKPKRAPKQKKVVEAVNSD-SDSEFGI-------------PK 1527 + + A++ + + + + + K++K +D ++E G P Sbjct: 322 ARRRELEARRRREQEEELRRLREQEKEEKERRRERADRGEAERGSGGSSGDELREDDEPV 381 Query: 1528 KTTTPKGKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKPKKTS 1571 K KG+GRG +S SE E + + +K ++KKP+ +S Sbjct: 382 KKRGRKGRGRGPP--SSSDSEPEAEL---EREAKKSAKKPQSSS 420 >gi|210032580 SET domain containing 1B [Homo sapiens] Length = 1923 Score = 49.3 bits (116), Expect = 3e-05 Identities = 50/190 (26%), Positives = 84/190 (44%), Gaps = 26/190 (13%) Query: 1283 EEALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPSAKKVK-KRNPWSDDESKSESDL 1341 ++ L PS +++ + + ++E + TP K K V +R P E S + Sbjct: 978 QKRLRPSTSVDE--EDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEE 1035 Query: 1342 EETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDDNNDLEELKVKASPITNDG 1401 +E E + ++S AE EE+++ DDDDDD++D +E + ND Sbjct: 1036 DEKESLSEEQESTEEEEEAE----------EEEEEEDDDDDDSDDRDESE-------NDD 1078 Query: 1402 EDEFV-----PSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDF-GNLFSFPSYSQKSEDD 1455 ED + +G +E T S SKA S +S +F + S PS S+ E+ Sbjct: 1079 EDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEV 1138 Query: 1456 SAKFDSNEED 1465 A+ + EE+ Sbjct: 1139 VAREEEEEEE 1148 Score = 43.5 bits (101), Expect = 0.002 Identities = 58/258 (22%), Positives = 97/258 (37%), Gaps = 46/258 (17%) Query: 1108 EAQEKAAEEDETQNQHDDSSSDSGTPSGPDFNYILNMS------------LWSLTKEKVE 1155 E +E+A EE+E ++ DD S D D + L+ + S+ K E Sbjct: 1049 EEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAE 1108 Query: 1156 ELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVESQEREDVLAGMSGKAIKGKV 1215 ++ E SPS E+ EE E +E E+++A Sbjct: 1109 ATSSSESSESSEFESSSESSPSSSEDEEEVVAREE---EEEEEEEEMVA----------- 1154 Query: 1216 GKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKKKGDLDTAAVKVEFDEEFSG 1275 EE+M S PE + D + L +D+ ++ E D E Sbjct: 1155 ----------EESMASAG-----PE--DFEQDGEEAALAPGAPAVDSLGMEEEVDIETEA 1197 Query: 1276 APVEGAGEEALTPSVPIN-KGPKPKRE-KKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDD 1333 E P +P+ + P RE +EPG S +P AK+V+ R P S + Sbjct: 1198 VAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPE 1257 Query: 1334 ES-KSESDLEETEPVVIP 1350 + + + ++E P+++P Sbjct: 1258 RAPEHDLEVEPEPPMMLP 1275 >gi|84043963 eukaryotic translation initiation factor 5B [Homo sapiens] Length = 1220 Score = 49.3 bits (116), Expect = 3e-05 Identities = 73/324 (22%), Positives = 126/324 (38%), Gaps = 49/324 (15%) Query: 1325 KKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDDN 1384 KK+ S+D +K + DL+ + + A + P+ + ++E D D+DD Sbjct: 3 KKQKNKSEDSTKDDIDLDALAAEIEGAGA----AKEQEPQKSKGKKKKEKKKQDFDEDDI 58 Query: 1385 -NDLEELKVKASPI-----------TNDGEDEFVPSD----GLDKDEYTFSPGKSKATPE 1428 +LEEL ++A I T + E+EF D G + +F S+ + Sbjct: 59 LKELEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELED 118 Query: 1429 KSLHDKK-----------SQDFGNLFSFPSYSQ-KSEDDSAKFDSNEEDSASVFSPSFGL 1476 K KK S D + P ++ K++ + K+D +EED + S + Sbjct: 119 KDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDN----SKKI 174 Query: 1477 KQTDKVPSKTVAAKKGKPSSDTVPKPKRAPKQKK-----VVEAVNSDSDSEFGIPKKTTT 1531 K+ ++ S + + G S + + K K +K +E+ N D D+ F I KT Sbjct: 175 KERSRINS---SGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKI--KTVA 229 Query: 1532 PKGKGRGAKKRKASGSENEGDYNPGRKTSKTTSKK--PKKTSFDQDSDVDIFPSDFPTEP 1589 K + ++RK E K T KK K+ + + + S + Sbjct: 230 QKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDT 289 Query: 1590 PSLPRTGRARKEVKYFAESDEEED 1613 +P + E AE D E D Sbjct: 290 GVIP-ASEEKAETPTAAEDDNEGD 312 Score = 39.3 bits (90), Expect = 0.031 Identities = 96/486 (19%), Positives = 180/486 (37%), Gaps = 55/486 (11%) Query: 1063 KLNNQARFILEKIQGKITIENRSKK----DLIQMLVQRGYESDPVKAWKEAQEKAAEED- 1117 K +A+ +K G E+ SKK I + G ESD ++ Q+K + Sbjct: 149 KAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKP 208 Query: 1118 ----ETQNQHDDSSSDSGTPSGPDFNYILNMSLWSLTKEKVEELIKQRDAKGREVNDLKR 1173 E+ N+ DD+S T + EK E K+RD + ++ LK Sbjct: 209 GPNIESGNEDDDASFKIKTVA-------------QKKAEKKERERKKRDEEKAKLRKLKE 255 Query: 1174 KSPSDLWKEDLAAFVEELDKVESQEREDVLAGMSG--KAIKGKVGKPKVKKLQLEETMPS 1231 K + K+D + E K E + + + +G A + K P + E Sbjct: 256 KEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNE----- 310 Query: 1232 PYGRRIIPEITAMKADASKKLLKKKKGD-------LDTAAVKVEFDEEFSGAPVEGAGEE 1284 G + + K + +K +KKKG + A K++ +EE E + Sbjct: 311 --GDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKR 368 Query: 1285 ALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSESDLEET 1344 + + ++EK+E + K K K + K + +++ L + Sbjct: 369 LEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQA 428 Query: 1345 EPVVIP-RDSLLRRAAAERPKYTFDFSEE-EDDDADDDDDDNNDLEEL------KVKASP 1396 + V +P +DSL ++ K ++ E + + + +E + K + P Sbjct: 429 QGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPP 488 Query: 1397 ITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLH--------DKKSQDFGNLFSFPSY 1448 E+E GLD E S +++ +H +++ ++ S Sbjct: 489 PVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESE 548 Query: 1449 SQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVPKPKRA-PK 1507 ++ E+ ++ +E+ V K DK PSK +++ S D K +RA K Sbjct: 549 EEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDK 608 Query: 1508 QKKVVE 1513 K+ +E Sbjct: 609 AKRRIE 614 >gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform a [Homo sapiens] Length = 845 Score = 48.9 bits (115), Expect = 4e-05 Identities = 70/290 (24%), Positives = 104/290 (35%), Gaps = 49/290 (16%) Query: 1298 PKREKKEP---GTRVRKTPTSSGKPSAKKVKK-RNPWSDDESKSESDLEETEPVVIPRDS 1353 PK++ EP G +P+ KK KK + + ++ + + E E V+ ++ Sbjct: 5 PKQQPPEPEWIGDGESTSPSDKVVKKGKKDKKIKKTFFEELAVEDKQAGEEEKVLKEKEQ 64 Query: 1354 LLRRAAAERPKYTFDFSEEEDDDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDK 1413 ++ ++ K D DDD ++ +E LK K S T+D EDE Sbjct: 65 QQQQQQQQQKKKRDTRKGRRKKDVDDDGEEKELMERLK-KLSVPTSDEEDE--------- 114 Query: 1414 DEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPS 1473 P K GN+F+ Q E+ EE+ P+ Sbjct: 115 ------------VPAPKPRGGKKTKGGNVFAALIQDQSEEE--------EEEEKHPPKPA 154 Query: 1474 FGLKQ--TDKVPSKTVAAKKGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTT 1531 K V + A KGK + K K P Q K N + D E I K+ Sbjct: 155 KPEKNRINKAVSEEQQPALKGKKGKEEKSKGKAKP-QNKFAALDNEEEDKEEEIIKEKEP 213 Query: 1532 PK-GKGRGAKKRKASGSENEGDY-----------NPGRKTSKTTSKKPKK 1569 PK GK + K + S E EG+ +P SK KK KK Sbjct: 214 PKQGKEKAKKAEQGSEEEGEGEEEEEEGGESKADDPYAHLSKKEKKKLKK 263 Score = 33.5 bits (75), Expect = 1.7 Identities = 51/239 (21%), Positives = 92/239 (38%), Gaps = 40/239 (16%) Query: 1149 LTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVESQEREDVLAGMSG 1208 + K EEL + G E LK K ++ ++ D + + ++DV Sbjct: 37 IKKTFFEELAVEDKQAGEEEKVLKEKEQQQQQQQQQQK--KKRDTRKGRRKKDVDDDGEE 94 Query: 1209 KAIKGKVGKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKKKGDLDTAAVKVE 1268 K + ++ K V E+ +P+P K KK K G++ A ++ + Sbjct: 95 KELMERLKKLSVPTSDEEDEVPAP------------KPRGGKKT---KGGNVFAALIQDQ 139 Query: 1269 FDEEFSGAPVEGAGEEALTPSVPI----NKGPKPKREKKEPGTRVRKTPTSSGKPSAKKV 1324 +EE EE P P N+ K E+++P + +K K AK Sbjct: 140 SEEE---------EEEEKHPPKPAKPEKNRINKAVSEEQQPALKGKKGKEEKSKGKAKPQ 190 Query: 1325 KKRNPW-SDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDD 1382 K +++E K E ++E EP + E+ K SEEE + +++++ Sbjct: 191 NKFAALDNEEEDKEEEIIKEKEPP---------KQGKEKAKKAEQGSEEEGEGEEEEEE 240 >gi|38788333 remodeling and spacing factor 1 [Homo sapiens] Length = 1441 Score = 48.5 bits (114), Expect = 5e-05 Identities = 65/286 (22%), Positives = 109/286 (38%), Gaps = 42/286 (14%) Query: 1356 RRAAAERPKYTFDFSEEEDDDADDDDDDNNDLEELKVKASPITNDGEDEFVPSD------ 1409 R AAA R K D D+D + D+ +E K I++ +DEFV SD Sbjct: 1079 RAAAARRKKRR----RLNDLDSDSNLDEEESEDEFK-----ISDGSQDEFVVSDENPDES 1129 Query: 1410 -----GLDKDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEE 1464 D + F + + P + + + P +D+ + + N Sbjct: 1130 EEDPPSNDDSDTDFCSRRLRRHPSRPMRQSRRL----RRKTPKKKYSDDDEEEESEENSR 1185 Query: 1465 DSASVFSPSFG-------LKQTDKVPSKTVAAKKGKPSSDTVPKPKRAPKQKKVVEAVNS 1517 DS S FS F +++ + + + K+ S + +R + ++V + S Sbjct: 1186 DSESDFSDDFSDDFVETRRRRSRRNQKRQINYKEDSESDGSQKSLRRGKEIRRVHKRRLS 1245 Query: 1518 DSDSEFGIPKKTT----TPKGKGRGAKKRKASGSE-NEGDYNPGRKTSKTTSKKPKKTSF 1572 S+SE K + K R +KR S E +E D + K + K+ + Sbjct: 1246 SSESEESYLSKNSEDDELAKESKRSVRKRGRSTDEYSEADEEEEEEEGKPSRKRLHRIET 1305 Query: 1573 DQDSDVDIFPSDF-----PTEPPSLPRTGRARKEVKYFAESDEEED 1613 D++ D D ++P LP + K+ Y ESDEEED Sbjct: 1306 DEEESCDNAHGDANQPARDSQPRVLPSEQESTKK-PYRIESDEEED 1350 >gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 [Homo sapiens] Length = 559 Score = 48.1 bits (113), Expect = 7e-05 Identities = 71/330 (21%), Positives = 125/330 (37%), Gaps = 48/330 (14%) Query: 1286 LTPSVPINKGPKPKREKKEPGTR-VRKTPTSSGKP-SAKKVKKRNPWSDDESKSESDLEE 1343 + P++P++ PK+ K G++ K + + KP K + P D ESKS S E Sbjct: 160 MLPTIPLSAFSDPKKTKPSHGSKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELE 219 Query: 1344 TEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDDNNDLEELKVKA-SPITNDGE 1402 E +D+ + PK E+ + L+E K+++ SP Sbjct: 220 REQAKSSKDTSRKLGEGRLPK-----EEKAPPPKAAFKEPKMALKETKLESTSPKGGPPP 274 Query: 1403 DEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSN 1462 P K T K A +K K S+ SA S Sbjct: 275 PPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSR------------------SAPGTSP 316 Query: 1463 EEDSASVFSPSFGLKQTDKVPSKTVAAKKG-KPSSDTVPKPKRAPKQKKVVEAVNSDSDS 1521 S+S FS DK P+K ++ +G K +++ P R K+ VE NS+ ++ Sbjct: 317 RTSSSSSFS--------DKKPAKDKSSTRGEKVKAESEP---REAKKALEVEESNSEDEA 365 Query: 1522 EFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKPKKTSFDQDSDVDIF 1581 F ++P + +S S ++ D+ P + S+ + + ++SD D Sbjct: 366 SFKSESAQSSP------SNSSSSSDSSSDSDFEPSQNHSQGPLRSMVEDLQSEESDED-- 417 Query: 1582 PSDFPTEPPSLPRTGRARKEVKYFAESDEE 1611 D + + +T R F++S+ + Sbjct: 418 --DSSSGEEAAGKTNPGRDSRLSFSDSESD 445 >gi|54124343 hypothetical protein LOC387680 [Homo sapiens] Length = 1341 Score = 48.1 bits (113), Expect = 7e-05 Identities = 72/292 (24%), Positives = 107/292 (36%), Gaps = 50/292 (17%) Query: 1374 DDDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDG-LDKDEYTFSPGK--SKATPEKS 1430 DDD DDDDD K + D F +G L K++ SP S+ K+ Sbjct: 452 DDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKA 511 Query: 1431 LHDKKSQDFGNLFSFPSYSQKSEDDSAK-FDSNEEDSASVFSPSFG--LKQTDKVPSKT- 1486 +KK L S + SE + K S+EEDS +FS LK +P K Sbjct: 512 RAEKKV----TLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLP 567 Query: 1487 ------------------VAAKKG----KPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFG 1524 AAKK + + K K+K +SD + ++ Sbjct: 568 TLVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWN 627 Query: 1525 IPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTS--------------KTTSKKPKKT 1570 IP T R + + SG+ + +KTS K + KK ++ Sbjct: 628 IPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRV 687 Query: 1571 SFDQDSDVDIFPSDFPTEPPSLPRTGRARK---EVKYFAESDEEEDDVDFAM 1619 S + DVD S F + P S+P + ++ E SDEEE + + Sbjct: 688 SLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGV 739 Score = 40.0 bits (92), Expect = 0.018 Identities = 72/327 (22%), Positives = 117/327 (35%), Gaps = 55/327 (16%) Query: 1333 DESKSESDLEETEPVVIPRDSLLRRAAAE-----RPKYTFDFSEEEDDDADDDDDDNNDL 1387 D K E D+E+ E P+ S A E + EE + L Sbjct: 264 DSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTL 323 Query: 1388 EELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPS 1447 +E K + +P ++ ++ F P D+D F G + K L D + ++ +LF Sbjct: 324 KEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEE-SDLF---- 378 Query: 1448 YSQKSEDDSAKFDSNEEDSAS-------VFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVP 1500 ++ +D A EE S+S + S L TD + +V + K +P P Sbjct: 379 -TEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMK-EPQKPEQP 436 Query: 1501 KPKRAPKQKKVV----EAVNSDSDSEFGIPKKTTTPKGKGRGAK-----------KRKAS 1545 P+++P + D D F P + GK + K KA Sbjct: 437 TPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAV 496 Query: 1546 GSE----NEGDYNPGRKTSKTT------------SKKPKKTSFDQDSDVDIFPSDFPTE- 1588 S ++ D N R K T +K K D++ D+F S ++ Sbjct: 497 ASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKL 556 Query: 1589 --PPSLPRTGRARKEVKYFAESDEEED 1613 LP G+ V F + DEE++ Sbjct: 557 KGASLLP--GKLPTLVSLFDDEDEEDN 581 >gi|104526627 triadin [Homo sapiens] Length = 729 Score = 48.1 bits (113), Expect = 7e-05 Identities = 101/482 (20%), Positives = 176/482 (36%), Gaps = 44/482 (9%) Query: 1151 KEKVEELIK-QRDAKGREVNDLKRKSPSD-LWKEDLAAFVEELDKVESQEREDVLAGMSG 1208 KEKV E K ++ A +E + K K + L KE A E K E + +++V G Sbjct: 171 KEKVREKEKPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAE--KSEEKTKKEV---KGG 225 Query: 1209 KAIKGKVGKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKKKGDLDTAAVKVE 1268 K K K KVK++Q + P K D K + K + A + Sbjct: 226 KQEKVKQTAAKVKEVQKTPSKPKE------------KEDKEKAAVSKHEQKDQYAFCRYM 273 Query: 1269 FDEEFSGAPVEGAGEEALTPSVPINKGPKP----------KREKKEPGTRVRKTPTSSGK 1318 D F ++ A+ P +P + +P + EKK+ +V K Sbjct: 274 IDI-FVHGDLKPGQSPAIPPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEK 332 Query: 1319 PSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDAD 1378 KK ++ D E K ET+ + + +AAA++ + D S++ A+ Sbjct: 333 EDIKKKSEKETAIDVEKKEPGKASETKQGTV---KIAAQAAAKKDEKKED-SKKTKKPAE 388 Query: 1379 DDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATP-EKSLHDKKSQ 1437 + E+ + P + ++ VPSD K + + + A +K++ KK + Sbjct: 389 VEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEE 448 Query: 1438 DFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSD 1497 +KS S+ E LK +K P K K + Sbjct: 449 KTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLK--EKEPETKKDEKMSKAGKE 506 Query: 1498 TVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGR 1557 PKP + +K+ +++ I +K K +K + G E + Sbjct: 507 VKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEKVLKQVK 566 Query: 1558 KTS--KTTSKKPKKTSFDQDSDVDIFPSDFPTEPP----SLPRTGRARKEVKYFAESDEE 1611 + KT KP K + ++ + +D P P + +G+ + E+ ES E+ Sbjct: 567 AVTIEKTAKPKPTKKAEHREREPPSIKTDKPKPTPKGTSEVTESGKKKTEISE-KESKEK 625 Query: 1612 ED 1613 D Sbjct: 626 AD 627 Score = 37.7 bits (86), Expect = 0.091 Identities = 88/420 (20%), Positives = 149/420 (35%), Gaps = 67/420 (15%) Query: 1148 SLTKEKVEELIKQRDAKGREVNDLKRKSPSDL--WKEDLAAFVEELDKVESQEREDVLAG 1205 S TK+K +E IK++ K + D+++K P K+ + + +++ED Sbjct: 325 SETKKKEKEDIKKKSEKETAI-DVEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKT 383 Query: 1206 MSGKAIKGKVGKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKKKGDLDTAAV 1265 ++ GK + KK + E SP +P +KA + Sbjct: 384 KKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAK------------- 430 Query: 1266 KVEFDEEFSGAPVEGAGEEALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPSAKKVK 1325 E G ++ +VP G K ++ K +RK SGK S+ +K Sbjct: 431 -------------EEIGAVSIKKAVP---GKKEEKTTKTVEQEIRKE--KSGKTSSI-LK 471 Query: 1326 KRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAE---RPKYTFDFSEEEDDDADDDDD 1382 + P E K + L+E EP +D + +A E +P EE+ + Sbjct: 472 DKEPIKGKEEKVPASLKEKEPET-KKDEKMSKAGKEVKPKPPQLQGKKEEKPE------- 523 Query: 1383 DNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFGNL 1442 ++K +A P + E + + K E T S GK + EK L K+ Sbjct: 524 -----PQIKKEAKPAIS--EKVQIHKQDIVKPEKTVSHGKPE---EKVLKQVKA------ 567 Query: 1443 FSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVPKP 1502 + ++ A+ E S P K T +V T + KK S+ K Sbjct: 568 VTIEKTAKPKPTKKAEHREREPPSIKTDKPKPTPKGTSEV---TESGKKKTEISEKESKE 624 Query: 1503 KRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEG--DYNPGRKTS 1560 K K + + + K P + + AS EG D +P ++ S Sbjct: 625 KADMKHLREEKVSTRKESLQLHNVTKAEKPARVSKDVEDVPASKKAKEGTEDVSPTKQKS 684 Score = 37.0 bits (84), Expect = 0.16 Identities = 58/294 (19%), Positives = 110/294 (37%), Gaps = 38/294 (12%) Query: 1354 LLRRAAAERPKYTFDF---------SEEEDDDADDDDDDNNDLEELKVKASPITNDGEDE 1404 L+R A E + + F SE+E+DD D+D D +++E ++ I D ++ Sbjct: 91 LVRDAMEETTDWIYGFFSLLSDIISSEDEEDDDGDEDTDKGEIDEPPLRKKEIHKDKTEK 150 Query: 1405 FVPSD--------------GLDKDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSYSQ 1450 + G +K P K KAT ++ + K+ + L ++ Sbjct: 151 QEKPERKIQTKVTHKEKEKGKEKVREKEKPEK-KATHKEKIEKKEKPETKTLAKEQKKAK 209 Query: 1451 KSE--DDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVPKPKRAPKQ 1508 +E ++ K + V + +K+ K PSK K K + K K Sbjct: 210 TAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKP----KEKEDKEKAAVSKHEQKD 265 Query: 1509 K----KVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGS--ENEGDYNPGRKTSKT 1562 + + + + D + G P + ++ AS + E EG+ K + Sbjct: 266 QYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTS 325 Query: 1563 TSKKPKKTSFDQDSDVDIFPSDFPTEPPSLPRT--GRARKEVKYFAESDEEEDD 1614 +KK +K + S+ + EP T G + + A+ DE+++D Sbjct: 326 ETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKKED 379 >gi|154090959 hypothetical protein LOC55747 [Homo sapiens] Length = 1253 Score = 48.1 bits (113), Expect = 7e-05 Identities = 72/292 (24%), Positives = 107/292 (36%), Gaps = 50/292 (17%) Query: 1374 DDDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDG-LDKDEYTFSPGK--SKATPEKS 1430 DDD DDDDD K + D F +G L K++ SP S+ K+ Sbjct: 364 DDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKA 423 Query: 1431 LHDKKSQDFGNLFSFPSYSQKSEDDSAK-FDSNEEDSASVFSPSFG--LKQTDKVPSKT- 1486 +KK L S + SE + K S+EEDS +FS LK +P K Sbjct: 424 RAEKKV----TLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLP 479 Query: 1487 ------------------VAAKKG----KPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFG 1524 AAKK + + K K+K +SD + ++ Sbjct: 480 TSVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWN 539 Query: 1525 IPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTS--------------KTTSKKPKKT 1570 IP T R + + SG+ + +KTS K + KK ++ Sbjct: 540 IPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRV 599 Query: 1571 SFDQDSDVDIFPSDFPTEPPSLPRTGRARK---EVKYFAESDEEEDDVDFAM 1619 S + DVD S F + P S+P + ++ E SDEEE + + Sbjct: 600 SLLFEDDVDSRGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGV 651 Score = 41.2 bits (95), Expect = 0.008 Identities = 72/327 (22%), Positives = 117/327 (35%), Gaps = 55/327 (16%) Query: 1333 DESKSESDLEETEPVVIPRDSLLRRAAAE-----RPKYTFDFSEEEDDDADDDDDDNNDL 1387 D K E D+E+ E P+ S A E + EE + L Sbjct: 176 DSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTL 235 Query: 1388 EELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPS 1447 +E K + +P ++ ++ F P D+D F G + K L D + ++ +LF Sbjct: 236 KEKKERRTPSDDEEDNLFTPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEE-SDLF---- 290 Query: 1448 YSQKSEDDSAKFDSNEEDSAS-------VFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVP 1500 ++ +D A EE S+S + S L TD + +V + K +P P Sbjct: 291 -TEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMK-EPQKPEQP 348 Query: 1501 KPKRAPKQKKVV----EAVNSDSDSEFGIPKKTTTPKGKGRGAK-----------KRKAS 1545 P+++P + D D F P + GK + K KA Sbjct: 349 TPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAV 408 Query: 1546 GSE----NEGDYNPGRKTSKTT------------SKKPKKTSFDQDSDVDIFPSDFPTE- 1588 S ++ D N R K T +K K D++ D+F S ++ Sbjct: 409 ASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKL 468 Query: 1589 --PPSLPRTGRARKEVKYFAESDEEED 1613 LP G+ V F + DEE++ Sbjct: 469 KGASLLP--GKLPTSVSLFDDEDEEDN 493 >gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 [Homo sapiens] Length = 540 Score = 47.8 bits (112), Expect = 9e-05 Identities = 82/380 (21%), Positives = 145/380 (38%), Gaps = 39/380 (10%) Query: 1206 MSGKAIKGKVGKPKVKKLQ------LEETMPSPYGRRIIPEITAMKADASKKLLKKKKGD 1259 +S K K KV PK+K +EET + +TA+ + + + ++KK Sbjct: 56 ISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEA 115 Query: 1260 LDTAAVKVEFDEEFSGAPVEGAGEEALTPSVPINKGPKPKREKKEP------GTRVRKTP 1313 + + E +EE A + + +A P V +G K + E +E G + + Sbjct: 116 AEEKEEEPEAEEEEVAA--KKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAE 173 Query: 1314 TSSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEE 1373 + K+ + E+++E++ EE E + A + + D E+ Sbjct: 174 EGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEK 233 Query: 1374 DDDADDDDDDNNDLEELK--VKASPITNDGEDEFV--PSDGLDKDEYTFSPGKSKATPEK 1429 + A + E+ K V SP+ G+ P + K SP + K Sbjct: 234 PEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV 293 Query: 1430 SLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAA 1489 S + + + P KS+ + K + EE+ K+ + P + Sbjct: 294 SKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEE----------KEVKEAPKEEKVE 343 Query: 1490 KKGKPSSDTVPKPKRAP---KQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRK--- 1543 KK + D VP+ K+A K++ V E V + + K+T +GK +K K Sbjct: 344 KKEEKPKD-VPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKE-EGKPLQQEKEKEKA 401 Query: 1544 --ASGSENEGDYNPGRKTSK 1561 GSE EG + G K S+ Sbjct: 402 GGEGGSEEEGS-DKGAKGSR 420 Score = 42.4 bits (98), Expect = 0.004 Identities = 62/263 (23%), Positives = 106/263 (40%), Gaps = 28/263 (10%) Query: 1082 ENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEDETQNQHDDSSSDSGTPSGPDFNYI 1141 E +KK ++ E + K +E QE+ EEDE + SD G + Sbjct: 129 EVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDE------GAKSDQAEEGGSEKEGS 182 Query: 1142 LNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVESQERED 1201 + + E + +A+ +E ++ KS KE+L A KVE E+ Sbjct: 183 SEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADA----KVEKPEKAK 238 Query: 1202 VLAGMSGKAIKGKVGKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKK-KGDL 1260 S K GK V K +EE SP + + E K+ K +++K K + Sbjct: 239 SPVPKSPVEEK---GKSPVPKSPVEEKGKSPVPKSPVEE--KGKSPVPKSPVEEKGKSPV 293 Query: 1261 DTAAVKVEFDEEFSGAPVEGAGEEALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPS 1320 + V+ + +PVE A +A + KG + + E+KE V++ P Sbjct: 294 SKSPVEEKAKSPVPKSPVEEAKSKA-----EVGKGEQKEEEEKE----VKEAPKEEKVEK 344 Query: 1321 AKKVKKRNPWSDDESKSESDLEE 1343 ++ K P ++ K+ES ++E Sbjct: 345 KEEKPKDVP---EKKKAESPVKE 364 Score = 32.7 bits (73), Expect = 2.9 Identities = 60/305 (19%), Positives = 107/305 (35%), Gaps = 26/305 (8%) Query: 1318 KPSAKKVKKRNPWSDD---ESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEED 1374 K A K+K ++ + ++ E+K E + E E + L + E K + EEE Sbjct: 64 KVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEP 123 Query: 1375 DDADDDDDDNNDLEELKVKASPI------TNDGEDEFVPSDGLDKDEYTFSPGKSKATPE 1428 + + EE+ K SP+ + E E +G +++E KS E Sbjct: 124 EAEE---------EEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEE 174 Query: 1429 KSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVA 1488 +K+ ++E + + ++ EE S K+ +K Sbjct: 175 GG-SEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEK 233 Query: 1489 AKKGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSE 1548 +K K VPK K K V + + +PK KGK K + Sbjct: 234 PEKAK---SPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGK 290 Query: 1549 NEGDYNPGRKTSKTTSKKPKKTSFDQDSDVDIFPSDFPTEPPSLPRTGRARKEVKYFAES 1608 + +P + +K S PK + S ++ + E A KE K + Sbjct: 291 SPVSKSPVEEKAK--SPVPKSPVEEAKSKAEVGKGEQKEEEEK--EVKEAPKEEKVEKKE 346 Query: 1609 DEEED 1613 ++ +D Sbjct: 347 EKPKD 351 >gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1 [Homo sapiens] Length = 651 Score = 47.8 bits (112), Expect = 9e-05 Identities = 89/420 (21%), Positives = 162/420 (38%), Gaps = 69/420 (16%) Query: 1231 SPYGRRIIPEITAMKADASKKLLKKKKGDLDTAAVKVEFDEEFSGAPVEGAGEEALTPSV 1290 +P ++I+ E T + +A K LK + + K + E E + +V Sbjct: 141 NPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSK---------SSSETNPESQNSKTV 191 Query: 1291 PINKGPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDD---ESKSESDLE----- 1342 N K K++ K ++ T K + KK KR+ S+D E SE+ L Sbjct: 192 SKNCSQKDKKDSKN--SKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLM 249 Query: 1343 ---ETEPVVIPRDSLLRRAAAERPK-YTFDFSE----------EEDDDADDDDDDNNDLE 1388 +++ I D+ LR + K Y+ +++ ++ DA+ +D + + Sbjct: 250 LVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKD 309 Query: 1389 ELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSY 1448 KVK + + D + + V D D + G SK + + DKK Sbjct: 310 SKKVKKN-VKKDDKKKDVKKDTESTDAES---GDSKDERKDTKKDKKKLK---------- 355 Query: 1449 SQKSEDDSAKF----DSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVPKPKR 1504 + D+ K+ D+ D+ + S LK+ K K AKK S+D+ Sbjct: 356 KDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDS------ 409 Query: 1505 APKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTSKTTS 1564 + +E+ S D + T K + ++ + SE +GD G+K K Sbjct: 410 ----ESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGK 465 Query: 1565 KKPKKTSFDQDSDVDIFPSDFPTE-------PPSLPRTGRARKEVKYFAESDEEEDDVDF 1617 K KK +D+ + ++ ++ S + G ++K++K A D E D +F Sbjct: 466 KDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSKEKKG-SKKDIKKDARKDTESTDAEF 524 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 47.8 bits (112), Expect = 9e-05 Identities = 79/411 (19%), Positives = 161/411 (39%), Gaps = 53/411 (12%) Query: 1171 LKRKSPSDLWKEDLAAFVEELDKVESQEREDVLAGMSGKAIKGKVGKPKVKKLQLEETMP 1230 L +K ++ E +E++ + S E+ + K + K+ K K LQ E P Sbjct: 1156 LVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQ--EKKP 1213 Query: 1231 SPYGRRIIPEITAMKADASKKLLKKKKGDLDTAAVKVEFDEEFSGAPVEGAGEEALTPSV 1290 P +++IPE ++++ K LL++KK T K E + AP E + L V Sbjct: 1214 LPEEKKLIPEEEKIRSEEKKPLLEEKK---PTPEDKKLLPEAKTSAP-EEQKHDLLKSQV 1269 Query: 1291 PINK-------GPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSESDLEE 1343 I + PK +E K+P T++ P SG P + +D+ +++ E+ Sbjct: 1270 QIAEEKLEGRVAPKTVQEGKQPQTKMEGLP--SGTPQSLP-------KEDDKTTKTIKEQ 1320 Query: 1344 TEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDDN----NDLEELKVKASPITN 1399 +P + + + +E+EDD +D L + + I++ Sbjct: 1321 PQPPCTAKPDQVEPGKEK--------TEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISS 1372 Query: 1400 D-GE-DEFVPSD------GLDKDEYTFSPGKSKATP------EKSLHDKKSQDFGNLFSF 1445 GE +P+D GL KD +FS S ++P E ++ L Sbjct: 1373 SLGEIPSLIPTDEKDILKGLKKD--SFSQESSPSSPSDLAKLESTVLSILEAQASTLADE 1430 Query: 1446 PSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKG---KPSSDTVPKP 1502 S + + + +++ S + + +++ ++ +K K S +P Sbjct: 1431 KSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSS 1490 Query: 1503 KRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDY 1553 K ++ + V+ + + + + + + + K+R + GS + +Y Sbjct: 1491 KDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEY 1541 Score = 43.5 bits (101), Expect = 0.002 Identities = 59/265 (22%), Positives = 102/265 (38%), Gaps = 21/265 (7%) Query: 1274 SGAPVEGAGEEALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDD 1333 S P + + ++ P ++K P+PK+ + K PT G PSAK K+ P +D Sbjct: 676 SPQPQQTSPKKDAAPKQDLSKAPEPKKPPP-----LVKQPTLHGSPSAKA--KQPPEADS 728 Query: 1334 ESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDDNNDLEELKVK 1393 SK E + +P + A ++PK D + D+ KV+ Sbjct: 729 LSKPAPPKEPS----VPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQ 784 Query: 1394 ASPITNDGEDEFVPSDGLD--KDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSYSQK 1451 + E++ P D K +F P K +P S + + S P S + Sbjct: 785 SQ-----AEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSE 839 Query: 1452 SEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKG-KPSS-DTVPKPKRAPKQK 1509 S+ +++ K K K G +P++ TVP P+++PK + Sbjct: 840 SKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQ 899 Query: 1510 KVVEAVNSDSDSEFGIPK-KTTTPK 1533 + + + S PK + TTP+ Sbjct: 900 EQSRRFSLNLGSITDAPKSQPTTPQ 924 Score = 39.7 bits (91), Expect = 0.024 Identities = 95/494 (19%), Positives = 177/494 (35%), Gaps = 66/494 (13%) Query: 1073 EKIQGKITIENRSKKDLIQMLVQRGYESDPVKAWK---EAQEKAAEEDETQNQHDDSSSD 1129 EK K + + Q L GY SD + + + E+D + DS S Sbjct: 1340 EKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQ 1399 Query: 1130 SGTPSGPDFNYILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWK-----EDL 1184 +PS P L ++ S+ + + L ++ K + +++ + P D K E L Sbjct: 1400 ESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETL 1459 Query: 1185 AAFVEELDKVESQ-EREDVLAGMSGKAI-KGKVGKPKVKKLQLEETMPSPYG-------- 1234 + E + ESQ ER+D S + I K K K + + T PY Sbjct: 1460 EITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSES 1519 Query: 1235 -------RRIIPEITAMKADASKKLLKKKKGD----LDTAAVKVEFDEEFSGAPVEGAGE 1283 R+ + + +D K+ + G+ + +++ DE+ SG+ + Sbjct: 1520 ENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIR 1579 Query: 1284 EAL---TPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKS--- 1337 L + S K + K + K + R+ S + +R+ W D++ ++ Sbjct: 1580 NQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDE 1639 Query: 1338 -------ESDLEETEPVVIPRDSLLRR---------------AAAERPKYTFDFSEEEDD 1375 E+ +E+E +V+ LRR A + + K + F EE + Sbjct: 1640 SPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPEL 1699 Query: 1376 DADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKK 1435 + + D D + +S + P+ DE + S K K + Sbjct: 1700 EMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKAR 1759 Query: 1436 SQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPS 1495 + G L P+ SE++ + EE+ ++Q + S +KK K Sbjct: 1760 HRPHGPL--LPTIEDSSEEEELR---EEEELLKEQEKQREIEQQQRKSS----SKKSKKD 1810 Query: 1496 SDTVPKPKRAPKQK 1509 D + +R + K Sbjct: 1811 KDELRAQRRRERPK 1824 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 47.8 bits (112), Expect = 9e-05 Identities = 79/411 (19%), Positives = 161/411 (39%), Gaps = 53/411 (12%) Query: 1171 LKRKSPSDLWKEDLAAFVEELDKVESQEREDVLAGMSGKAIKGKVGKPKVKKLQLEETMP 1230 L +K ++ E +E++ + S E+ + K + K+ K K LQ E P Sbjct: 1156 LVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQ--EKKP 1213 Query: 1231 SPYGRRIIPEITAMKADASKKLLKKKKGDLDTAAVKVEFDEEFSGAPVEGAGEEALTPSV 1290 P +++IPE ++++ K LL++KK T K E + AP E + L V Sbjct: 1214 LPEEKKLIPEEEKIRSEEKKPLLEEKK---PTPEDKKLLPEAKTSAP-EEQKHDLLKSQV 1269 Query: 1291 PINK-------GPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSESDLEE 1343 I + PK +E K+P T++ P SG P + +D+ +++ E+ Sbjct: 1270 QIAEEKLEGRVAPKTVQEGKQPQTKMEGLP--SGTPQSLP-------KEDDKTTKTIKEQ 1320 Query: 1344 TEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDDN----NDLEELKVKASPITN 1399 +P + + + +E+EDD +D L + + I++ Sbjct: 1321 PQPPCTAKPDQVEPGKEK--------TEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISS 1372 Query: 1400 D-GE-DEFVPSD------GLDKDEYTFSPGKSKATP------EKSLHDKKSQDFGNLFSF 1445 GE +P+D GL KD +FS S ++P E ++ L Sbjct: 1373 SLGEIPSLIPTDEKDILKGLKKD--SFSQESSPSSPSDLAKLESTVLSILEAQASTLADE 1430 Query: 1446 PSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKG---KPSSDTVPKP 1502 S + + + +++ S + + +++ ++ +K K S +P Sbjct: 1431 KSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSS 1490 Query: 1503 KRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDY 1553 K ++ + V+ + + + + + + + K+R + GS + +Y Sbjct: 1491 KDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEY 1541 Score = 43.5 bits (101), Expect = 0.002 Identities = 59/265 (22%), Positives = 102/265 (38%), Gaps = 21/265 (7%) Query: 1274 SGAPVEGAGEEALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDD 1333 S P + + ++ P ++K P+PK+ + K PT G PSAK K+ P +D Sbjct: 676 SPQPQQTSPKKDAAPKQDLSKAPEPKKPPP-----LVKQPTLHGSPSAKA--KQPPEADS 728 Query: 1334 ESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDDNNDLEELKVK 1393 SK E + +P + A ++PK D + D+ KV+ Sbjct: 729 LSKPAPPKEPS----VPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQ 784 Query: 1394 ASPITNDGEDEFVPSDGLD--KDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSYSQK 1451 + E++ P D K +F P K +P S + + S P S + Sbjct: 785 SQ-----AEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSE 839 Query: 1452 SEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKG-KPSS-DTVPKPKRAPKQK 1509 S+ +++ K K K G +P++ TVP P+++PK + Sbjct: 840 SKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQ 899 Query: 1510 KVVEAVNSDSDSEFGIPK-KTTTPK 1533 + + + S PK + TTP+ Sbjct: 900 EQSRRFSLNLGSITDAPKSQPTTPQ 924 Score = 39.7 bits (91), Expect = 0.024 Identities = 95/494 (19%), Positives = 177/494 (35%), Gaps = 66/494 (13%) Query: 1073 EKIQGKITIENRSKKDLIQMLVQRGYESDPVKAWK---EAQEKAAEEDETQNQHDDSSSD 1129 EK K + + Q L GY SD + + + E+D + DS S Sbjct: 1340 EKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQ 1399 Query: 1130 SGTPSGPDFNYILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWK-----EDL 1184 +PS P L ++ S+ + + L ++ K + +++ + P D K E L Sbjct: 1400 ESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETL 1459 Query: 1185 AAFVEELDKVESQ-EREDVLAGMSGKAI-KGKVGKPKVKKLQLEETMPSPYG-------- 1234 + E + ESQ ER+D S + I K K K + + T PY Sbjct: 1460 EITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSES 1519 Query: 1235 -------RRIIPEITAMKADASKKLLKKKKGD----LDTAAVKVEFDEEFSGAPVEGAGE 1283 R+ + + +D K+ + G+ + +++ DE+ SG+ + Sbjct: 1520 ENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIR 1579 Query: 1284 EAL---TPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKS--- 1337 L + S K + K + K + R+ S + +R+ W D++ ++ Sbjct: 1580 NQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDE 1639 Query: 1338 -------ESDLEETEPVVIPRDSLLRR---------------AAAERPKYTFDFSEEEDD 1375 E+ +E+E +V+ LRR A + + K + F EE + Sbjct: 1640 SPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPEL 1699 Query: 1376 DADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKK 1435 + + D D + +S + P+ DE + S K K + Sbjct: 1700 EMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKAR 1759 Query: 1436 SQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPS 1495 + G L P+ SE++ + EE+ ++Q + S +KK K Sbjct: 1760 HRPHGPL--LPTIEDSSEEEELR---EEEELLKEQEKQREIEQQQRKSS----SKKSKKD 1810 Query: 1496 SDTVPKPKRAPKQK 1509 D + +R + K Sbjct: 1811 KDELRAQRRRERPK 1824 >gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sapiens] Length = 2997 Score = 47.4 bits (111), Expect = 1e-04 Identities = 54/183 (29%), Positives = 74/183 (40%), Gaps = 28/183 (15%) Query: 1452 SEDDSAKFDSNE----EDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVPKPKRAPK 1507 +ED S F ++ D+ + S Q +K K AKK P PK K+ PK Sbjct: 608 AEDPSKGFGKDDFPGGVDNQELNRNSLDGSQEEKKKKKRSKAKKD-PKEPKEPKEKKEPK 666 Query: 1508 QKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKP 1567 + K +A IPK+ K K K + + S N+ P + S K Sbjct: 667 EPKTPKAPK--------IPKEPKEKKAKTATPKPKSSKKSSNK---KPDSEASALKKKVN 715 Query: 1568 K-KTSFDQDSDVDIFPSDFP----TEPPSLP--RTGRARKEVKY-----FAESDEEEDDV 1615 K KT ++SD+D P P E P + R+ R K +Y F SDEE DD Sbjct: 716 KGKTEGSENSDLDKTPPPSPPPEEDEDPGVQKRRSSRQVKRKRYTEDLEFKISDEEADDA 775 Query: 1616 DFA 1618 D A Sbjct: 776 DAA 778 Score = 42.0 bits (97), Expect = 0.005 Identities = 49/159 (30%), Positives = 67/159 (42%), Gaps = 30/159 (18%) Query: 1240 EITAMKADASKKLLKKKKGDLDTAAVKVEFDEEFSGAPVEGAGEEALTPSVPINKGPK-P 1298 E+ D S++ KKKK K + D + P E +E P P K PK P Sbjct: 628 ELNRNSLDGSQEEKKKKKRS------KAKKDPKEPKEPKEK--KEPKEPKTP--KAPKIP 677 Query: 1299 KREKKEPGTRVRKTPTSSGKPSAKK-------VKKRNPWSDDESKSESDLEETEPVVIPR 1351 K K++ P SS K S KK +KK+ E SDL++T P P Sbjct: 678 KEPKEKKAKTATPKPKSSKKSSNKKPDSEASALKKKVNKGKTEGSENSDLDKTPPPSPPP 737 Query: 1352 DS------LLRRAA--AERPKYT----FDFSEEEDDDAD 1378 + RR++ +R +YT F S+EE DDAD Sbjct: 738 EEDEDPGVQKRRSSRQVKRKRYTEDLEFKISDEEADDAD 776 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.132 0.381 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 62,797,122 Number of Sequences: 37866 Number of extensions: 3054302 Number of successful extensions: 15442 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 58 Number of HSP's successfully gapped in prelim test: 408 Number of HSP's that attempted gapping in prelim test: 12655 Number of HSP's gapped (non-prelim): 2074 length of query: 1621 length of database: 18,247,518 effective HSP length: 116 effective length of query: 1505 effective length of database: 13,855,062 effective search space: 20851868310 effective search space used: 20851868310 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.