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Search of human proteins with 19913408
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19913408 DNA topoisomerase II, beta isozyme [Homo sapiens]
(1621 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19913408 DNA topoisomerase II, beta isozyme [Homo sapiens] 3262 0.0
gi|19913406 DNA topoisomerase II, alpha isozyme [Homo sapiens] 2112 0.0
gi|55956788 nucleolin [Homo sapiens] 62 3e-09
gi|217330641 IWS1 homolog [Homo sapiens] 62 5e-09
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 59 4e-08
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 55 6e-07
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 54 9e-07
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 54 9e-07
gi|16445033 ACRC protein [Homo sapiens] 54 9e-07
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 54 1e-06
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 54 1e-06
gi|59814411 hypothetical protein LOC253725 [Homo sapiens] 52 4e-06
gi|55741677 SET domain containing 1A [Homo sapiens] 52 5e-06
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 51 8e-06
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi... 50 1e-05
gi|48255931 hepatoma-derived growth factor-related protein 2 iso... 50 2e-05
gi|14249158 hepatoma-derived growth factor-related protein 2 iso... 50 2e-05
gi|210032580 SET domain containing 1B [Homo sapiens] 49 3e-05
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 49 3e-05
gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform... 49 4e-05
gi|38788333 remodeling and spacing factor 1 [Homo sapiens] 49 5e-05
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora... 48 7e-05
gi|54124343 hypothetical protein LOC387680 [Homo sapiens] 48 7e-05
gi|104526627 triadin [Homo sapiens] 48 7e-05
gi|154090959 hypothetical protein LOC55747 [Homo sapiens] 48 7e-05
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 48 9e-05
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 48 9e-05
gi|150170670 piccolo isoform 2 [Homo sapiens] 48 9e-05
gi|150378539 piccolo isoform 1 [Homo sapiens] 48 9e-05
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa... 47 1e-04
>gi|19913408 DNA topoisomerase II, beta isozyme [Homo sapiens]
Length = 1621
Score = 3262 bits (8458), Expect = 0.0
Identities = 1621/1621 (100%), Positives = 1621/1621 (100%)
Query: 1 MAKSGGCGAGAGVGGGNGALTWVNNAAKKEESETANKNDSSKKLSVERVYQKKTQLEHIL 60
MAKSGGCGAGAGVGGGNGALTWVNNAAKKEESETANKNDSSKKLSVERVYQKKTQLEHIL
Sbjct: 1 MAKSGGCGAGAGVGGGNGALTWVNNAAKKEESETANKNDSSKKLSVERVYQKKTQLEHIL 60
Query: 61 LRPDTYIGSVEPLTQFMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTC 120
LRPDTYIGSVEPLTQFMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTC
Sbjct: 61 LRPDTYIGSVEPLTQFMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTC 120
Query: 121 IKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNG 180
IKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNG
Sbjct: 121 IKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNG 180
Query: 181 YGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLS 240
YGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLS
Sbjct: 181 YGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLS 240
Query: 241 KFKMEKLDKDIVALMTRRAYDLAGSCRGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGV 300
KFKMEKLDKDIVALMTRRAYDLAGSCRGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGV
Sbjct: 241 KFKMEKLDKDIVALMTRRAYDLAGSCRGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGV 300
Query: 301 ALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKK 360
ALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKK
Sbjct: 301 ALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKK 360
Query: 361 NKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASN 420
NKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASN
Sbjct: 361 NKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASN 420
Query: 421 CGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDS 480
CGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDS
Sbjct: 421 CGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDS 480
Query: 481 AKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDD 540
AKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDD
Sbjct: 481 AKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDD 540
Query: 541 AESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNK 600
AESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNK
Sbjct: 541 AESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNK 600
Query: 601 QELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPE 660
QELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPE
Sbjct: 601 QELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPE 660
Query: 661 DDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELI 720
DDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELI
Sbjct: 661 DDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELI 720
Query: 721 LFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQAL 780
LFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQAL
Sbjct: 721 LFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQAL 780
Query: 781 MMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSTLARLLFPAVDDN 840
MMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSTLARLLFPAVDDN
Sbjct: 781 MMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSTLARLLFPAVDDN 840
Query: 841 LLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGLD 900
LLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGLD
Sbjct: 841 LLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGLD 900
Query: 901 PHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPML 960
PHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPML
Sbjct: 901 PHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPML 960
Query: 961 NGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFD 1020
NGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFD
Sbjct: 961 NGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFD 1020
Query: 1021 HMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKIT 1080
HMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKIT
Sbjct: 1021 HMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKIT 1080
Query: 1081 IENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEDETQNQHDDSSSDSGTPSGPDFNY 1140
IENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEDETQNQHDDSSSDSGTPSGPDFNY
Sbjct: 1081 IENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEDETQNQHDDSSSDSGTPSGPDFNY 1140
Query: 1141 ILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVESQERE 1200
ILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVESQERE
Sbjct: 1141 ILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVESQERE 1200
Query: 1201 DVLAGMSGKAIKGKVGKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKKKGDL 1260
DVLAGMSGKAIKGKVGKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKKKGDL
Sbjct: 1201 DVLAGMSGKAIKGKVGKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKKKGDL 1260
Query: 1261 DTAAVKVEFDEEFSGAPVEGAGEEALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPS 1320
DTAAVKVEFDEEFSGAPVEGAGEEALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPS
Sbjct: 1261 DTAAVKVEFDEEFSGAPVEGAGEEALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPS 1320
Query: 1321 AKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDD 1380
AKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDD
Sbjct: 1321 AKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDD 1380
Query: 1381 DDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFG 1440
DDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFG
Sbjct: 1381 DDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFG 1440
Query: 1441 NLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVP 1500
NLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVP
Sbjct: 1441 NLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVP 1500
Query: 1501 KPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTS 1560
KPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTS
Sbjct: 1501 KPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTS 1560
Query: 1561 KTTSKKPKKTSFDQDSDVDIFPSDFPTEPPSLPRTGRARKEVKYFAESDEEEDDVDFAMF 1620
KTTSKKPKKTSFDQDSDVDIFPSDFPTEPPSLPRTGRARKEVKYFAESDEEEDDVDFAMF
Sbjct: 1561 KTTSKKPKKTSFDQDSDVDIFPSDFPTEPPSLPRTGRARKEVKYFAESDEEEDDVDFAMF 1620
Query: 1621 N 1621
N
Sbjct: 1621 N 1621
>gi|19913406 DNA topoisomerase II, alpha isozyme [Homo sapiens]
Length = 1531
Score = 2112 bits (5471), Expect = 0.0
Identities = 1091/1599 (68%), Positives = 1259/1599 (78%), Gaps = 96/1599 (6%)
Query: 25 NAAKKEESETANKNDSSKKLSVERVYQKKTQLEHILLRPDTYIGSVEPLTQFMWVYDEDV 84
N KK E D+ K+LSVER+YQKKTQLEHILLRPDTYIGSVE +TQ MWVYDEDV
Sbjct: 16 NKIKKNE-------DAKKRLSVERIYQKKTQLEHILLRPDTYIGSVELVTQQMWVYDEDV 68
Query: 85 GMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTCIKVSIDPESNIISIWNNGKGIPVV 144
G+N REVTFVPGLYKIFDEILVNAADNKQRD M+CI+V+IDPE+N+ISIWNNGKGIPVV
Sbjct: 69 GINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVV 128
Query: 145 EHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVETACKEYKH 204
EHKVEK+YVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVETA +EYK
Sbjct: 129 EHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKK 188
Query: 205 SFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLSKFKMEKLDKDIVALMTRRAYDLAG 264
FKQTWM+NM + E ++K F+GEDYTCITFQPDLSKFKM+ LDKDIVALM RRAYD+AG
Sbjct: 189 MFKQTWMDNMGRAGEMELKPFNGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAG 248
Query: 265 SCRGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGVALKVIHELANERWDVCLTLSEKGF 324
S + VKV NG KLPV GFRSYVD+Y+KDKLDETG +LKVIHE N RW+VCLT+SEKGF
Sbjct: 249 STKDVKVFLNGNKLPVKGFRSYVDMYLKDKLDETGNSLKVIHEQVNHRWEVCLTMSEKGF 308
Query: 325 QQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKKNKAGVSVKPFQVKNHIWVFINCLI 384
QQISFVNSIAT+KGGRHVDYV DQ+V KL++VVKKKNK GV+VK QVKNH+W+F+N LI
Sbjct: 309 QQISFVNSIATSKGGRHVDYVADQIVTKLVDVVKKKNKGGVAVKAHQVKNHMWIFVNALI 368
Query: 385 ENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASNCGIVESILNWVKFKAQTQLNKKCS 444
ENPTFDSQTKENMTLQPKSFGS CQLSEKF KAA CGIVESILNWVKFKAQ QLNKKCS
Sbjct: 369 ENPTFDSQTKENMTLQPKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQVQLNKKCS 428
Query: 445 SVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDSAKSLAVSGLGVIGRDRYGVFPLRG 504
+VK+++IKGIPKLDDANDAGG++S ECTLILTEGDSAK+LAVSGLGV+GRD+YGVFPLRG
Sbjct: 429 AVKHNRIKGIPKLDDANDAGGRNSTECTLILTEGDSAKTLAVSGLGVVGRDKYGVFPLRG 488
Query: 505 KILNVREASHKQIMENAEINNIIKIVGLQYKKSYDDAESLKTLRYGKIMIMTDQDQDGSH 564
KILNVREASHKQIMENAEINNIIKIVGLQYKK+Y+D +SLKTLRYGKIMIMTDQDQDGSH
Sbjct: 489 KILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMTDQDQDGSH 548
Query: 565 IKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNKQELSFYSIPEFDEWKKHIENQKAW 624
IKGLLINFIHHNWPSLL+H FLEEFITPIVK SKNKQE++FYS+PEF+EWK N K W
Sbjct: 549 IKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKSSTPNHKKW 608
Query: 625 KIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPEDDAAITLAFSKKKIDDRKEWLTNF 684
K+KYYKGLGTST+KEAKEYFADM+RHRI F+Y+GPEDDAAI+LAFSKK+IDDRKEWLTNF
Sbjct: 609 KVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDDRKEWLTNF 668
Query: 685 MEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELILFSNSDNERSIPSLVDGFKPGQRK 744
MEDRRQR+L GLPE +LYG T +LTYNDFINKELILFSNSDNERSIPS+VDG KPGQRK
Sbjct: 669 MEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVDGLKPGQRK 728
Query: 745 VLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQALMMTIVNLAQNFVGSNNINLLQPIG 804
VLFTCFKRNDKREVKVAQLAGSVAEMS+YHHGE +LMMTI+NLAQNFVGSNN+NLLQPIG
Sbjct: 729 VLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNNLNLLQPIG 788
Query: 805 QFGTRLHGGKDAASPRYIFTMLSTLARLLFPAVDDNLLKFLYDDNQRVEPEWYIPIIPMV 864
QFGTRLHGGKD+ASPRYIFTMLS+LARLLFP DD+ LKFLYDDNQRVEPEWYIPIIPMV
Sbjct: 789 QFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLKFLYDDNQRVEPEWYIPIIPMV 848
Query: 865 LINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGLDPHPMLPNYKNFKGTIQELGQNQYA 924
LINGAEGIGTGW+CK+PN+D REIVNN+RR++DG +P PMLP+YKNFKGTI+EL NQY
Sbjct: 849 LINGAEGIGTGWSCKIPNFDVREIVNNIRRLMDGEEPLPMLPSYKNFKGTIEELAPNQYV 908
Query: 925 VSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPMLNGTDKTPALISDYKEYHTDTTVKF 984
+SGE+ +++ T+EI+ELPVRTWTQ YKEQVLEPMLNGT+KTP LI+DY+EYHTDTTVKF
Sbjct: 909 ISGEVAILNSTTIEISELPVRTWTQTYKEQVLEPMLNGTEKTPPLITDYREYHTDTTVKF 968
Query: 985 VVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFDHMGCLKKYETVQDILKEFFDLRLS 1044
VVKMTEEKLA+AE GLHKVFKLQT+LTCNSMVLFDH+GCLKKY+TV DIL++FF+LRL
Sbjct: 969 VVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILRDFFELRLK 1028
Query: 1045 YYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKITIENRSKKDLIQMLVQRGYESDPVK 1104
YYGLRKEWL+GMLGAES KLNNQARFILEKI GKI IEN+ KK+LI++L+QRGY+SDPVK
Sbjct: 1029 YYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQRGYDSDPVK 1088
Query: 1105 AWKEAQEKAAEEDETQ---NQHDDSSSDSGTPSGPDFNYILNMSLWSLTKEKVEELIKQR 1161
AWKEAQ+K +E+E + N+ + SDS T SGP FNY+L+M LW LTKEK +EL + R
Sbjct: 1089 AWKEAQQKVPDEEENEESDNEKETEKSDSVTDSGPTFNYLLDMPLWYLTKEKKDELCRLR 1148
Query: 1162 DAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVESQEREDVLAGMSGKAIKGKVGKPKVK 1221
+ K +E++ LKRKSPSDLWKEDLA F+EEL+ VE++E++D G+ GK GK K K
Sbjct: 1149 NEKEQELDTLKRKSPSDLWKEDLATFIEELEAVEAKEKQDEQVGLPGKG-----GKAKGK 1203
Query: 1222 KLQLEETMPSPYGRRIIPEITA-MKADASKKLLKKKKGDLDTAAVKVEFDEEFSGAPVEG 1280
K Q+ E +PSP G+R+IP IT MKA+A KK KK K + E + G +EG
Sbjct: 1204 KTQMAEVLPSPRGQRVIPRITIEMKAEAEKKNKKKIKNE------NTEGSPQEDGVELEG 1257
Query: 1281 AGEEALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSESD 1340
+ K++K+EPGT+ +K T + KP KK KKRNPWSD ES SD
Sbjct: 1258 LKQRL------------EKKQKREPGTKTKKQTTLAFKP-IKKGKKRNPWSDSESDRSSD 1304
Query: 1341 LEETEPVVIPRDSLLRRAAAERPKYTFDFSEEED-DDADDDDDDNNDLEELKVKASPITN 1399
E+ V PR++ RRAA + K+T D +ED D D+ DD
Sbjct: 1305 --ESNFDVPPRETEPRRAAT-KTKFTMDLDSDEDFSDFDEKTDD---------------- 1345
Query: 1400 DGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKF 1459
++FVPSD SP K+K +P+ S + K Q S E D K
Sbjct: 1346 ---EDFVPSDA--------SPPKTKTSPKLSNKELKPQK--------SVVSDLEADDVKG 1386
Query: 1460 DSNEEDSASVFSPSFGLKQTDKVPSKTV-----AAKKGKPSSDTVPKPKRAPKQKKVVEA 1514
S + T+ VP K V AAK +S T K + APK K A
Sbjct: 1387 SVPLSSSPPATHFPDETEITNPVPKKNVTVKKTAAKSQSSTSTTGAKKRAAPKGTKRDPA 1446
Query: 1515 VNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTSKT-TSKKPKKTSFD 1573
+NS G+ +K K K R +KRK S S+ + D N + SK TSKK K S D
Sbjct: 1447 LNS------GVSQKPDPAKTKNR--RKRKPSTSD-DSDSNFEKIVSKAVTSKKSKGESDD 1497
Query: 1574 QDSDVDIFPSDFPTEPPSLPRTGRARKEVKYFAESDEEE 1612
F DF + ++ RA+K +KY ESDE++
Sbjct: 1498 -------FHMDFDSAVAPRAKSVRAKKPIKYLEESDEDD 1529
Score = 41.2 bits (95), Expect = 0.008
Identities = 65/270 (24%), Positives = 110/270 (40%), Gaps = 41/270 (15%)
Query: 1369 FSEEEDDDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPE 1428
+ E + D+++++ +D E+ K+ +T+ G P+ D + K K
Sbjct: 1090 WKEAQQKVPDEEENEESDNEKETEKSDSVTDSG-----PTFNYLLDMPLWYLTKEKKDEL 1144
Query: 1429 KSLHDKKSQDFGNLFSFPSYSQKSEDDSAKF-------DSNEEDSASVFSPSFGLKQTDK 1481
L ++K Q+ L S S ++D A F ++ E+ V P G K K
Sbjct: 1145 CRLRNEKEQELDTL-KRKSPSDLWKEDLATFIEELEAVEAKEKQDEQVGLPGKGGKAKGK 1203
Query: 1482 VP--SKTVAAKKGK---PSSDTVPKPKRAPKQKKVVEAVNSD-SDSEFGIPKKTTTPKGK 1535
++ + + +G+ P K + K KK ++ N++ S E G+ +
Sbjct: 1204 KTQMAEVLPSPRGQRVIPRITIEMKAEAEKKNKKKIKNENTEGSPQEDGVELE------- 1256
Query: 1536 GRGAKKRKASGSENEGDYNPGRKTSKTTS------KKPKKTS--FDQDSDVDIFPSDFPT 1587
G K+R + E PG KT K T+ KK KK + D +SD S+F
Sbjct: 1257 --GLKQRLEKKQKRE----PGTKTKKQTTLAFKPIKKGKKRNPWSDSESDRSSDESNFDV 1310
Query: 1588 EPPSLPRTGRARKEVKYFAESDEEEDDVDF 1617
PP RA + K+ + D +ED DF
Sbjct: 1311 -PPRETEPRRAATKTKFTMDLDSDEDFSDF 1339
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 62.4 bits (150), Expect = 3e-09
Identities = 72/284 (25%), Positives = 115/284 (40%), Gaps = 45/284 (15%)
Query: 1237 IIPEITAMKADAS--KKLLKK--KKGDLDTAAVK--VEFDEEFSGAPVEGAGEEALTPSV 1290
+IP+ KA A+ KK++ KK + T A K V ++ + P + A +
Sbjct: 47 VIPQKKGKKAAATSAKKVVVSPTKKVAVATPAKKAAVTPGKKAAATPAKKTVTPAKAVTT 106
Query: 1291 PINKGPKP-KREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVI 1349
P KG P K PG + P K + K KK + +++ SE D E+ E
Sbjct: 107 PGKKGATPGKALVATPGKKGAAIPAKGAK-NGKNAKKEDSDEEEDDDSEEDEEDDEDEDE 165
Query: 1350 PRDSL---LRRAAAERPKYTFDFSEEEDDDADDDDDDNNDLEELKVKASPITNDGEDEFV 1406
D + +AAA P + E+++DD DDDDD+ +D EE ++ +P + V
Sbjct: 166 DEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVV 225
Query: 1407 PSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDS 1466
P K+ A E D + +D + + EDD + D EE+
Sbjct: 226 P-----------VKAKNVAEDEDEEEDDEDEDDDD-------DEDDEDDDDEDDEEEEE- 266
Query: 1467 ASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVPKPKRAPKQKK 1510
+ ++ P K K+ K + K K AP+ KK
Sbjct: 267 -----------EEEEEPVKEAPGKRKK----EMAKQKAAPEAKK 295
Score = 35.8 bits (81), Expect = 0.35
Identities = 47/199 (23%), Positives = 68/199 (34%), Gaps = 18/199 (9%)
Query: 1421 GKSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSAS-VFSPSFGLKQT 1479
GK++ P+K K + + SED+ D ++ S V P K+
Sbjct: 8 GKNQGDPKKMAPPPKEVE-----------EDSEDEEMSEDEEDDSSGEEVVIPQKKGKKA 56
Query: 1480 DKVPSKTVAAKKGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGA 1539
+K V K + P K A K +A + + K TTP KG
Sbjct: 57 AATSAKKVVVSPTKKVAVATPAKKAAVTPGK--KAAATPAKKTVTPAKAVTTPGKKGATP 114
Query: 1540 KKRKASGSENEGDYNP--GRKTSKTTSKKPKKTSFDQDSDVDIFPSDFPTEPPSLPRTGR 1597
K + +G P G K K K+ D DS+ D D E
Sbjct: 115 GKALVATPGKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEED--EEDDEDEDEDEDEIEP 172
Query: 1598 ARKEVKYFAESDEEEDDVD 1616
A + A + E+EDD D
Sbjct: 173 AAMKAAAAAPASEDEDDED 191
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 62.0 bits (149), Expect = 5e-09
Identities = 119/524 (22%), Positives = 193/524 (36%), Gaps = 97/524 (18%)
Query: 1118 ETQNQHDDSSSDSGTPSGPDFNYILNMSLWSL--TKEKVEELIKQRDAKGREVNDLKRKS 1175
E ++++ S + G P G N +L + + EEL +Q+D+ E +
Sbjct: 46 ERHSENETSDREDGLPKGHHVTDSENDEPLNLNASDSESEELHRQKDSDS-ESEERAEPP 104
Query: 1176 PSDLWKEDLAAFVEELDKVESQ-------EREDVLAGMSGKAIKGKVGKPKVKKLQLEET 1228
SD ED+ + + E++ E E++L G + + VGK ++EE
Sbjct: 105 ASDSENEDVNQHGSDSESEETRKLPGSDSENEELLNGHASDSENEDVGKHPASDSEIEEL 164
Query: 1229 MPSPYGRRIIPEITAMKADASKKLLKKKKGDLDTA-AVKVEFDEEFSGAPVEGAGEEALT 1287
SP D +T A+K + + S P ++
Sbjct: 165 QKSP------------------------ASDSETEDALKPQISDSESEEPPRHQASDSEN 200
Query: 1288 PSVPINKGPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSE-----SDLE 1342
+ PKP+ E + P S + R+ SD E++ SD E
Sbjct: 201 -----EEPPKPRMSDSES----EELPKPQVSDSESEEPPRHQASDSENEELPKPRISDSE 251
Query: 1343 ETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDDNNDLEELKVKASPITNDGE 1402
+P PR E PK SE ED + D N EEL P +D E
Sbjct: 252 SEDP---PRHQASDSENEELPKPRISDSESEDPPRNQASDSEN--EEL---PKPRVSDSE 303
Query: 1403 DEFVPSDGLDKDEYTFSPGKSKATPEK-SLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDS 1461
E P G D T + K PE D++++ S+ S D KF S
Sbjct: 304 SE-GPQKGPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHS 362
Query: 1462 NEEDSASVFSPSFGLKQTDKV-PSKTVAAKKGKPSSDTVPKPKRAPKQKKVV-EAVNSDS 1519
++ + + +K + VA +K SD+ + K + K+ +VV +A +SDS
Sbjct: 363 SDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSDS 422
Query: 1520 DSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKPKKTSFDQDSDVD 1579
D+ + GK +K AS SE E K+ S ++ + D
Sbjct: 423 DA-------VSDKSGK---REKTIASDSEEEAG---------------KELSDKKNEEKD 457
Query: 1580 IFPSDFPTEPPSLPRTGRARKEV--KYFAESDEEEDDVDFAMFN 1621
+F SD +G + + F ES +EE++ +F FN
Sbjct: 458 LFGSD--------SESGNEEENLIADIFGESGDEEEE-EFTGFN 492
Score = 61.6 bits (148), Expect = 6e-09
Identities = 100/452 (22%), Positives = 164/452 (36%), Gaps = 60/452 (13%)
Query: 1094 VQRGYESDPVKAWKEAQEKAAEEDETQNQHDDSSSDSGTPSGPDFNYILNMSLWSLTKEK 1153
+ R +SD + + E+E NQH S T P + L +
Sbjct: 87 LHRQKDSDSESEERAEPPASDSENEDVNQHGSDSESEETRKLPGSDSENEELLNGHASDS 146
Query: 1154 VEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVESQEREDVLAGMSGKAIKG 1213
E + + A E+ +L++ SD ED ++ E E+ + +
Sbjct: 147 ENEDVGKHPASDSEIEELQKSPASDSETEDALK-----PQISDSESEEPPRHQASDSENE 201
Query: 1214 KVGKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKKKGDLDTAAVKVEFDEEF 1273
+ KP++ + EE +P P +++ +++ + + + ++ D E
Sbjct: 202 EPPKPRMSDSESEE-LPKP-------QVSDSESEEPPRHQASDSENEELPKPRIS-DSES 252
Query: 1274 SGAPVEGAG----EEALTPSVPINKGPKPKREKKE-------PGTRV--------RKTPT 1314
P A EE P + ++ P R + P RV +K P
Sbjct: 253 EDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQKGPA 312
Query: 1315 SSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEED 1374
S + K+ P SDD+S E+ E+TE + DS + +R K+ SEEE+
Sbjct: 313 SDSETEDASRHKQKPESDDDSDRENKGEDTE---MQNDSFHSDSHMDRKKFHSSDSEEEE 369
Query: 1375 DDAD--DDDDDNNDLEELKV--KASPITNDGEDE--------FVPSDGLDKDEYTFSPGK 1422
D D+D + EE KV + + + +D EDE V SD D D S
Sbjct: 370 HKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSDSDAVSDKS 429
Query: 1423 SKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDS--ASVFSPS------- 1473
K EK++ ++ G S +K S NEE++ A +F S
Sbjct: 430 GKR--EKTIASDSEEEAGKELSDKKNEEKDLFGSDSESGNEEENLIADIFGESGDEEEEE 487
Query: 1474 -FGLKQTDKVPSKTVAAKKGKPSSDTVPKPKR 1504
G Q D K K SD+ KR
Sbjct: 488 FTGFNQEDLEEEKGETQVKEAEDSDSDDNIKR 519
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 58.9 bits (141), Expect = 4e-08
Identities = 106/502 (21%), Positives = 181/502 (36%), Gaps = 77/502 (15%)
Query: 1108 EAQEKAAEEDETQNQHDDSSSDS----GTPSGPDFNYILNMSLWSLTKEKVEELIKQRDA 1163
E + +EDE DSS++S G G + ++ ++ S +KE + K+ D
Sbjct: 255 EDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKE-DP 313
Query: 1164 KGREVNDLKRKSPSD---LWKEDLAAFVEELDKVESQEREDVLAGMSGKAIKGKVGKPKV 1220
D KS + + +++ + +E+ K+ +E + V ++ ++ VGK +
Sbjct: 314 HNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQD 373
Query: 1221 KKLQLEETMPSPYGRRIIPEI---TAMKADASKKLLKKKKGDLDTAAVKVEFDEEFSGAP 1277
K ++++ PS R I E+ K D + + KG++ T V
Sbjct: 374 KGIEIKG--PSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVN--------- 422
Query: 1278 VEGAGEEALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPSA---------KKVKKRN 1328
+EG G+ K EPG +V + T S S K ++ +
Sbjct: 423 IEGPGQ------------------KSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDD 464
Query: 1329 PWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDDNNDLE 1388
P S DES D +S R A+ + D D +DDD ++ +
Sbjct: 465 PNSSDESNGNDDANSESD----NNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSD 520
Query: 1389 ELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSY 1448
++ N+G D D D+ GKS ++ S S D + S
Sbjct: 521 TNNSDSNGNGNNGND--------DNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSS 572
Query: 1449 SQKSEDDSAKFD--------------SNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKP 1494
S DS D SN DS+ S +D SK+ ++K
Sbjct: 573 DSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESD 632
Query: 1495 SSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYN 1554
SSD+ K + + NSDS S+ ++ + +S S N D +
Sbjct: 633 SSDSDSKSDSSDSNSS-DSSDNSDS-SDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSS 690
Query: 1555 PGRKTSKTTSKKPKKTSFDQDS 1576
+S ++ S D DS
Sbjct: 691 DSSDSSNSSESSDSSDSSDSDS 712
Score = 43.9 bits (102), Expect = 0.001
Identities = 37/212 (17%), Positives = 73/212 (34%), Gaps = 1/212 (0%)
Query: 1368 DFSEEEDDDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATP 1427
D S+ D D+ D + ++ + +D D SD D + + S S ++
Sbjct: 562 DSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSD 621
Query: 1428 EKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTV 1487
KS K D + S S + DS+ +S+ DS++ + S +D S +
Sbjct: 622 SKSDSSKSESDSSDSDSKSDSSDSNSSDSSD-NSDSSDSSNSSNSSDSSDSSDSSDSSSS 680
Query: 1488 AAKKGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGS 1547
+ S + + ++ +SDS ++ + +S S
Sbjct: 681 SDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNS 740
Query: 1548 ENEGDYNPGRKTSKTTSKKPKKTSFDQDSDVD 1579
+ D + +S ++ S D D
Sbjct: 741 SDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSD 772
Score = 43.9 bits (102), Expect = 0.001
Identities = 47/267 (17%), Positives = 91/267 (34%), Gaps = 3/267 (1%)
Query: 1315 SSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEED 1374
SS ++ + SD S+SD + DS +++ + D S+ D
Sbjct: 794 SSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSS-DSSDGSD 852
Query: 1375 DDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDK 1434
D+ + D +N + S ++D D ++ + + + S S + S +
Sbjct: 853 SDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSS 912
Query: 1435 KSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKP 1494
S D N S S++ ++ SN DS+ S ++ S +
Sbjct: 913 DSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSN 972
Query: 1495 SSDTVPKPKRAPKQKKVVEAVNSDS--DSEFGIPKKTTTPKGKGRGAKKRKASGSENEGD 1552
SSD+ + + +SDS S ++ + +S S N D
Sbjct: 973 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSD 1032
Query: 1553 YNPGRKTSKTTSKKPKKTSFDQDSDVD 1579
+ +S ++ S D + D
Sbjct: 1033 SSDSSDSSDSSDSSDSSDSSDSSNSSD 1059
Score = 42.4 bits (98), Expect = 0.004
Identities = 53/266 (19%), Positives = 85/266 (31%), Gaps = 16/266 (6%)
Query: 1315 SSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEED 1374
SS S+ N +S + SD ++ DS + + D S+ D
Sbjct: 815 SSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDS--DSSNRSDSSNSSDSSDSSD 872
Query: 1375 DDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDK 1434
D D++D E S ++D D SD D S + S
Sbjct: 873 SSNSSDSSDSSDSNE-----SSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESS 927
Query: 1435 KSQDFGNLFSFPSYSQKSEDDSAKFD-SNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGK 1493
S D N S S S D S D SN DS++ S +D S + +
Sbjct: 928 NSSDNSN----SSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSS 983
Query: 1494 PSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDY 1553
SSD+ + ++ NS S+ ++ + +S S + D
Sbjct: 984 DSSDSSDSSDSSDSS----DSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDS 1039
Query: 1554 NPGRKTSKTTSKKPKKTSFDQDSDVD 1579
+ +S ++ S D D
Sbjct: 1040 SDSSDSSDSSDSSDSSNSSDSSDSSD 1065
Score = 41.6 bits (96), Expect = 0.006
Identities = 52/271 (19%), Positives = 93/271 (34%), Gaps = 29/271 (10%)
Query: 1314 TSSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEE 1373
+ S S+ + S D S S + E ++ DS ++ + S+ +
Sbjct: 672 SDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDS----SDSSDSDSSDSSDSSNSNSSDSD 727
Query: 1374 DDDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHD 1433
++ D D +N + S ++D D S+ D + + S S ++ +D
Sbjct: 728 SSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSND 787
Query: 1434 KKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGK 1493
+ + S S S S D S DS++ DS++ S +D S + +
Sbjct: 788 SSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDS--SNSSDSSDSS 845
Query: 1494 PSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDY 1553
SSD SDSDS + + +S S + D
Sbjct: 846 DSSD------------------GSDSDS-----SNRSDSSNSSDSSDSSDSSNSSDSSDS 882
Query: 1554 NPGRKTSKTTSKKPKKTSFDQDSDVDIFPSD 1584
+ ++S ++ S D DS SD
Sbjct: 883 SDSNESSNSSDSSDSSNSSDSDSSDSSNSSD 913
Score = 41.2 bits (95), Expect = 0.008
Identities = 49/266 (18%), Positives = 87/266 (32%), Gaps = 15/266 (5%)
Query: 1315 SSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEED 1374
SS + + SD +S + SD + DS + D S+ D
Sbjct: 835 SSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDS----------SNSSDSSDSSD 884
Query: 1375 DDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDK 1434
+ + D++D S +++ D S+ D E + S S ++ + D
Sbjct: 885 SNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDS 944
Query: 1435 KSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVA-AKKGK 1493
+ S S S S + S DSN DS+ + S +D S + +
Sbjct: 945 SDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSS 1004
Query: 1494 PSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDY 1553
SSD+ + ++ NS S ++ + +S S N D
Sbjct: 1005 DSSDS----SDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1060
Query: 1554 NPGRKTSKTTSKKPKKTSFDQDSDVD 1579
+ +S ++ S D D
Sbjct: 1061 SDSSDSSDSSDSSDSSDSSDSSESSD 1086
Score = 40.8 bits (94), Expect = 0.011
Identities = 45/249 (18%), Positives = 87/249 (34%), Gaps = 11/249 (4%)
Query: 1331 SDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDDNNDLEEL 1390
SD +S + SD ++ DS +++ + + + D+ D D ++
Sbjct: 724 SDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSS 783
Query: 1391 KVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSYSQ 1450
S ++D D SD + + + S S + S S D + S S
Sbjct: 784 DSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSD----SSNSS 839
Query: 1451 KSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVPKPKRAPKQKK 1510
S D S D ++ DS++ S +D S SSD+ + +
Sbjct: 840 DSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSN-----SSDSSDSSDSNESSNSSDS 894
Query: 1511 VVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKPKKT 1570
+ +SDSDS ++ + ++S S + + + +S ++
Sbjct: 895 SDSSNSSDSDSSDS--SNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSN 952
Query: 1571 SFDQDSDVD 1579
S D + D
Sbjct: 953 SSDSSNSSD 961
Score = 39.3 bits (90), Expect = 0.031
Identities = 60/346 (17%), Positives = 105/346 (30%), Gaps = 25/346 (7%)
Query: 1246 ADASKKLLKKKKGDLDTAAVKVEFDEEFSGAPVEGAGEEALTPSVPINKGPKPKREKKEP 1305
+D+S K + D++ + D S + ++ S N
Sbjct: 617 SDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSD 676
Query: 1306 GTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKY 1365
+ + SS + + SD S+SD ++ DS ++
Sbjct: 677 SSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSS------DSSNSNSSDSDSSN 730
Query: 1366 TFDFSEEEDD-DADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSK 1424
+ D S+ + D+ D D +N + S ++D D SD D + S S
Sbjct: 731 SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSN 790
Query: 1425 ATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFD-----------SNEEDSASVFSPS 1473
++ S S D N S S+ DS+ SN DS+ S
Sbjct: 791 SSD--SSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSS 848
Query: 1474 FGLKQTDKVPSKTVAAKKGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPK 1533
G S + + SSD+ + N S+S ++
Sbjct: 849 DGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDS-----NESSNSSDSSDSSNSSDS 903
Query: 1534 GKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKPKKTSFDQDSDVD 1579
+ +S S N D + +S ++ S D D
Sbjct: 904 DSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSD 949
Score = 38.9 bits (89), Expect = 0.041
Identities = 45/273 (16%), Positives = 90/273 (32%), Gaps = 3/273 (1%)
Query: 1314 TSSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEE 1373
+S+ S+ + +S + SD ++ DS +++ + +
Sbjct: 728 SSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSND 787
Query: 1374 DDDADDDDDDNNDLEELKVKASPITNDGEDEFVP--SDGLDKDEYTFSPGKSKATPEKSL 1431
++ D D +N + S ++D D SD + + + S S ++
Sbjct: 788 SSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDS 847
Query: 1432 HDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKK 1491
D D N + S S+ + S+ DS+ S +D S +
Sbjct: 848 SDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSD 907
Query: 1492 GKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEG 1551
SSD+ + + + NS+S S+ ++ + +S S N
Sbjct: 908 SSNSSDSSDSSNSSDSSESSNSSDNSNS-SDSSNSSDSSDSSDSSNSSDSSNSSDSSNSS 966
Query: 1552 DYNPGRKTSKTTSKKPKKTSFDQDSDVDIFPSD 1584
D + + + S +S DS SD
Sbjct: 967 DSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSD 999
Score = 38.9 bits (89), Expect = 0.041
Identities = 60/305 (19%), Positives = 101/305 (33%), Gaps = 30/305 (9%)
Query: 1314 TSSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEE 1373
+S+ S+ N +S SD ++ DS + D S+
Sbjct: 1015 SSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS----------SNSSDSSDSS 1064
Query: 1374 DDDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHD 1433
D D D++D + S ++D D SD D + + S S ++ D
Sbjct: 1065 DSSDSSDSSDSSDSSD-----SSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSD 1119
Query: 1434 KKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGK 1493
+ + S S S S + S DS+E +S S S S + +
Sbjct: 1120 SSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDS----------SDSSDSSDSS 1169
Query: 1494 PSSDTVPKPKRAPKQKKVVEAVNSDS--DSEFGIPKKTTTPKGKGRGAKKRKASGSENEG 1551
SSD+ + + +SDS S+ ++ + +S S +
Sbjct: 1170 DSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1229
Query: 1552 DYNPGRKTSKTTSKKPKKTSFD--QDSDVDIFPSDFPTEPPSLPRTGRARKEVKYFAESD 1609
D N +S ++ S D SD SD E S ++G ++SD
Sbjct: 1230 DSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGS-DSDSD 1288
Query: 1610 EEEDD 1614
E D
Sbjct: 1289 SEGSD 1293
Score = 38.5 bits (88), Expect = 0.053
Identities = 49/251 (19%), Positives = 84/251 (33%), Gaps = 23/251 (9%)
Query: 1331 SDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDD-----DDDNN 1385
SD SD + DS +++ D S+ E D +D D D N
Sbjct: 588 SDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSN- 646
Query: 1386 DLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSF 1445
++D D SD + + S S ++ S D + + S
Sbjct: 647 ------------SSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSD 694
Query: 1446 PSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVPKPKRA 1505
S S +S D S DS+ DS S S +D S + + SSD+ +
Sbjct: 695 SSNSSESSDSSDSSDSDSSDS----SDSSNSNSSDSDSSNSSDSSDSSNSSDS-SDSSDS 749
Query: 1506 PKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTSKTTSK 1565
++ +S + S+ ++ + +S S + D + +S ++
Sbjct: 750 SNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDS 809
Query: 1566 KPKKTSFDQDS 1576
S D DS
Sbjct: 810 SDSSDSSDSDS 820
Score = 33.9 bits (76), Expect = 1.3
Identities = 44/263 (16%), Positives = 82/263 (31%), Gaps = 11/263 (4%)
Query: 1315 SSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDF----S 1370
SS + + + SD + S+SD ++ DS ++E + + S
Sbjct: 879 SSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDS 938
Query: 1371 EEEDDDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKS 1430
D +D D N+ S ++D + SD D S + S
Sbjct: 939 SNSSDSSDSSDSSNS-------SDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDS 991
Query: 1431 LHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAK 1490
S D N S S+ ++ SN DS++ S +D S +
Sbjct: 992 SDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1051
Query: 1491 KGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENE 1550
+S + ++ +S SE ++ + +S S +
Sbjct: 1052 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDS 1111
Query: 1551 GDYNPGRKTSKTTSKKPKKTSFD 1573
D + +S ++ S D
Sbjct: 1112 SDSSDSSDSSNSSDSSDSSDSSD 1134
Score = 33.5 bits (75), Expect = 1.7
Identities = 35/213 (16%), Positives = 71/213 (33%), Gaps = 3/213 (1%)
Query: 1368 DFSEEEDDDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATP 1427
D S+ + D D++D + ++ ++D D SD + + + S S ++
Sbjct: 975 DSSDSSNSSDSSDSSDSSDSSDSSDSSN--SSDSSDSSDSSDSSNSSDSSNSSDSSNSSD 1032
Query: 1428 EKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNE-EDSASVFSPSFGLKQTDKVPSKT 1486
D + S S S S D S DS++ DS+ S + +D S
Sbjct: 1033 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSN 1092
Query: 1487 VAAKKGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASG 1546
+ S + ++ NS S+ ++ + ++S
Sbjct: 1093 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSD 1152
Query: 1547 SENEGDYNPGRKTSKTTSKKPKKTSFDQDSDVD 1579
S + D + +S ++ S + D
Sbjct: 1153 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1185
Score = 33.1 bits (74), Expect = 2.2
Identities = 39/269 (14%), Positives = 83/269 (30%), Gaps = 5/269 (1%)
Query: 1316 SGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDD 1375
S S+ + N +S S+ ++ +S +++ + S + +
Sbjct: 851 SDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSN 910
Query: 1376 DADDDDDDNNDLEELKVKASPITNDGE-----DEFVPSDGLDKDEYTFSPGKSKATPEKS 1430
+D D N+ +S +N + D SD + + + S S ++
Sbjct: 911 SSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSD 970
Query: 1431 LHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAK 1490
+ S D N S S+ + SN DS+ S +D S +
Sbjct: 971 SNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNS 1030
Query: 1491 KGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENE 1550
S + ++ NS S+ ++ + ++S S +
Sbjct: 1031 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDS 1090
Query: 1551 GDYNPGRKTSKTTSKKPKKTSFDQDSDVD 1579
+ + +S ++ S D D
Sbjct: 1091 SNSSDSSDSSDSSDSSDSSDSSDSSDSSD 1119
>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
Length = 1163
Score = 55.1 bits (131), Expect = 6e-07
Identities = 90/397 (22%), Positives = 151/397 (38%), Gaps = 57/397 (14%)
Query: 1225 LEETMPSPYGRRIIP---EITAMKADASKKLLKKKKGDLDTAAVKVEFDEEFSGAPVEGA 1281
+++ S GR+ P + T + KK KK A K +E G +E
Sbjct: 536 IQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKK--------AEKAAAEEPRGGLKIESE 587
Query: 1282 GEEALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSESDL 1341
L S+P ++ + ++P ++K SS +P+A+K KK S KS +
Sbjct: 588 TPVDLASSMPSSRHKAATKGSRKPN--IKKESKSSPRPTAEK-KKYKSTSKSSQKSREII 644
Query: 1342 EETEPVVIPRDSLLRRAAAERPKYTFDF------SEEEDDDADDDDDDNNDLEELKVKAS 1395
E +S +++ PKY S E++D+ + +EE K S
Sbjct: 645 ETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEE-KELLS 703
Query: 1396 PITNDGEDEFVPSDGLDKDEYTFSPGK-----------SKATPEKSLHDKKSQDFGNLFS 1444
P++ + +D + +D + T PGK K PEK + + Q + +
Sbjct: 704 PLS-EPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSN 762
Query: 1445 FPSYSQKSEDDS----AKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVP 1500
K+EDD+ +K E+ +++ PS +++ SK AAK+ D +P
Sbjct: 763 KGKRKHKNEDDNRASESKKPKTEDKNSAGHKPS-----SNRESSKQSAAKE----KDLLP 813
Query: 1501 KPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKG---KGRGAKKRKASGSENEGDYNPGR 1557
P K D +E G K+T + + K + S+N + +
Sbjct: 814 SPAGPVPSK--------DPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQK 865
Query: 1558 KTSKTTSKKPKKTSFDQDSDVDIFPSDFPTEPPSLPR 1594
KT TS K+ S P PT S PR
Sbjct: 866 KTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPR 902
>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
Length = 1758
Score = 54.3 bits (129), Expect = 9e-07
Identities = 100/511 (19%), Positives = 188/511 (36%), Gaps = 48/511 (9%)
Query: 1074 KIQGKITIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEDETQNQHDDSSSDSGT- 1132
K K E++ K + + V++ Y D +E+ A++ +N+ D+ +
Sbjct: 1056 KAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKR 1115
Query: 1133 ---PSGPDFNYILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVE 1189
G D ++ S ++K +V E++K + E + K + K L+A +
Sbjct: 1116 KTEEKGVDKDF--ESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAK 1173
Query: 1190 ELD-------KVESQEREDVLAGMSGK--AIKGKVGKPKVKKLQLEETMPSPYGRRIIPE 1240
++ K+ S E S K + KV + KVK + + + +
Sbjct: 1174 KIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVD 1233
Query: 1241 ITAMKADASKKLLKKKKGDLDTAAVKVEFDEEFSGAPVEGAGEEALTPSVPINKGPKPKR 1300
T+ + + +K + DT ++ EE++ A + + VP +K K
Sbjct: 1234 YTSTSSTGGSPV-RKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDF 1292
Query: 1301 EKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAA 1360
E +E + + +S GKP++ S+ E + E +E +
Sbjct: 1293 ESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKI------------- 1339
Query: 1361 ERPKYTFDFSEEEDDDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSP 1420
K+T D S E ++ E+ K T D + + + +K
Sbjct: 1340 --QKFTKDVSHEIIQHEVKSSKNSASSEKGK------TKDRDYSVLEKENPEK------- 1384
Query: 1421 GKSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTD 1480
K+ PEK + + + GN F S S K S K DS S F+P+ K+TD
Sbjct: 1385 RKNSTQPEKESNLDRLNEQGN-FKSLSQSSKEARTSDKHDSTRASSNKDFTPNRD-KKTD 1442
Query: 1481 KVPSKTVAAKKGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAK 1540
+ ++K+ ++ + + K + E +PKK T K +
Sbjct: 1443 YDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSP 1502
Query: 1541 KRKASGSENEGDYNPGRKTSKTTS--KKPKK 1569
R +++ Y+ R +T S K P K
Sbjct: 1503 SRDRKPHDHKATYDTKRPNEETKSVDKNPCK 1533
Score = 38.5 bits (88), Expect = 0.053
Identities = 47/235 (20%), Positives = 89/235 (37%), Gaps = 16/235 (6%)
Query: 1120 QNQHDDSSSDSGTPSGPDFNYILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDL 1179
+ +H + ++ SG YILN + KE++ I + K + + SDL
Sbjct: 1535 REKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDL 1594
Query: 1180 WKE-DLAAFVEELDKVESQE----REDVLAGMSGKAIKGKVGKPKVKKLQLEETMPSPYG 1234
+E D AAF + ++ +S+ +E+ +G K +K K+ + + L +
Sbjct: 1595 TRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGIS 1654
Query: 1235 RRIIPEITAMKADASKKLLKKKKGDLDTAAVKVEFDEEFSGAPVEGAGEEALTPSVPINK 1294
R ++ +S + + + + S + ++ K
Sbjct: 1655 RN--------QSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKK 1706
Query: 1295 GPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVI 1349
K K+ KK GT V + K KK KK D E + E D ++ + V +
Sbjct: 1707 HKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKN---KDKEKEKEKDDQKVKSVTV 1758
Score = 37.0 bits (84), Expect = 0.16
Identities = 34/166 (20%), Positives = 63/166 (37%), Gaps = 13/166 (7%)
Query: 1412 DKDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFS 1471
+ DE F P +++ E ++ K+ + GN+ S+ +D + D+A+V
Sbjct: 1597 ETDEAAFEPDYNESDSESNVSVKEEESSGNI------SKDLKDKIVEKAKESLDTAAVVQ 1650
Query: 1472 PSFGLKQTDKVPSKTVAAKKGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTT 1531
Q+ PS + PS P + + S + K+
Sbjct: 1651 VGISRNQSHSSPSVS-------PSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKK 1703
Query: 1532 PKGKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKPKKTSFDQDSD 1577
K + K +K +G+E E + + K K SKK K +++ D
Sbjct: 1704 HKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKD 1749
Score = 33.5 bits (75), Expect = 1.7
Identities = 48/276 (17%), Positives = 102/276 (36%), Gaps = 36/276 (13%)
Query: 1299 KREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRA 1358
+R++K TR + +P+ + ++ + K D K D +++ S R
Sbjct: 1453 RRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSN------SSPSRDR 1506
Query: 1359 AAERPKYTFDFSEEEDDDADDDDDDNNDLEELKVKASPITNDGEDEFV-----PSDGLDK 1413
K T+D ++ D + D E+ ++A ++ + P ++K
Sbjct: 1507 KPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEK 1566
Query: 1414 DEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPS 1473
++ T KS P+ L S+S + D + E + F P
Sbjct: 1567 EQITGQIDKSTVKPKPQL---------------SHSSRLSSDLTR-----ETDEAAFEPD 1606
Query: 1474 FGLKQTDKVPSKTVAAKKGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPK 1533
+ ++ S++ + K + SS + K + +K E++++ + + GI + +
Sbjct: 1607 Y-----NESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSS 1661
Query: 1534 GKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKPKK 1569
++ SGS+ + SKK KK
Sbjct: 1662 PSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKK 1697
>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
Length = 1792
Score = 54.3 bits (129), Expect = 9e-07
Identities = 100/511 (19%), Positives = 188/511 (36%), Gaps = 48/511 (9%)
Query: 1074 KIQGKITIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEDETQNQHDDSSSDSGT- 1132
K K E++ K + + V++ Y D +E+ A++ +N+ D+ +
Sbjct: 1090 KAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKR 1149
Query: 1133 ---PSGPDFNYILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVE 1189
G D ++ S ++K +V E++K + E + K + K L+A +
Sbjct: 1150 KTEEKGVDKDF--ESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAK 1207
Query: 1190 ELD-------KVESQEREDVLAGMSGK--AIKGKVGKPKVKKLQLEETMPSPYGRRIIPE 1240
++ K+ S E S K + KV + KVK + + + +
Sbjct: 1208 KIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVD 1267
Query: 1241 ITAMKADASKKLLKKKKGDLDTAAVKVEFDEEFSGAPVEGAGEEALTPSVPINKGPKPKR 1300
T+ + + +K + DT ++ EE++ A + + VP +K K
Sbjct: 1268 YTSTSSTGGSPV-RKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDF 1326
Query: 1301 EKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAA 1360
E +E + + +S GKP++ S+ E + E +E +
Sbjct: 1327 ESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKI------------- 1373
Query: 1361 ERPKYTFDFSEEEDDDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSP 1420
K+T D S E ++ E+ K T D + + + +K
Sbjct: 1374 --QKFTKDVSHEIIQHEVKSSKNSASSEKGK------TKDRDYSVLEKENPEK------- 1418
Query: 1421 GKSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTD 1480
K+ PEK + + + GN F S S K S K DS S F+P+ K+TD
Sbjct: 1419 RKNSTQPEKESNLDRLNEQGN-FKSLSQSSKEARTSDKHDSTRASSNKDFTPNRD-KKTD 1476
Query: 1481 KVPSKTVAAKKGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAK 1540
+ ++K+ ++ + + K + E +PKK T K +
Sbjct: 1477 YDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSP 1536
Query: 1541 KRKASGSENEGDYNPGRKTSKTTS--KKPKK 1569
R +++ Y+ R +T S K P K
Sbjct: 1537 SRDRKPHDHKATYDTKRPNEETKSVDKNPCK 1567
Score = 38.5 bits (88), Expect = 0.053
Identities = 47/235 (20%), Positives = 89/235 (37%), Gaps = 16/235 (6%)
Query: 1120 QNQHDDSSSDSGTPSGPDFNYILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDL 1179
+ +H + ++ SG YILN + KE++ I + K + + SDL
Sbjct: 1569 REKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDL 1628
Query: 1180 WKE-DLAAFVEELDKVESQE----REDVLAGMSGKAIKGKVGKPKVKKLQLEETMPSPYG 1234
+E D AAF + ++ +S+ +E+ +G K +K K+ + + L +
Sbjct: 1629 TRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGIS 1688
Query: 1235 RRIIPEITAMKADASKKLLKKKKGDLDTAAVKVEFDEEFSGAPVEGAGEEALTPSVPINK 1294
R ++ +S + + + + S + ++ K
Sbjct: 1689 RN--------QSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKK 1740
Query: 1295 GPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVI 1349
K K+ KK GT V + K KK KK D E + E D ++ + V +
Sbjct: 1741 HKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKN---KDKEKEKEKDDQKVKSVTV 1792
Score = 37.0 bits (84), Expect = 0.16
Identities = 34/166 (20%), Positives = 63/166 (37%), Gaps = 13/166 (7%)
Query: 1412 DKDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFS 1471
+ DE F P +++ E ++ K+ + GN+ S+ +D + D+A+V
Sbjct: 1631 ETDEAAFEPDYNESDSESNVSVKEEESSGNI------SKDLKDKIVEKAKESLDTAAVVQ 1684
Query: 1472 PSFGLKQTDKVPSKTVAAKKGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTT 1531
Q+ PS + PS P + + S + K+
Sbjct: 1685 VGISRNQSHSSPSVS-------PSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKK 1737
Query: 1532 PKGKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKPKKTSFDQDSD 1577
K + K +K +G+E E + + K K SKK K +++ D
Sbjct: 1738 HKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKD 1783
Score = 33.5 bits (75), Expect = 1.7
Identities = 48/276 (17%), Positives = 102/276 (36%), Gaps = 36/276 (13%)
Query: 1299 KREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRA 1358
+R++K TR + +P+ + ++ + K D K D +++ S R
Sbjct: 1487 RRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSN------SSPSRDR 1540
Query: 1359 AAERPKYTFDFSEEEDDDADDDDDDNNDLEELKVKASPITNDGEDEFV-----PSDGLDK 1413
K T+D ++ D + D E+ ++A ++ + P ++K
Sbjct: 1541 KPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEK 1600
Query: 1414 DEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPS 1473
++ T KS P+ L S+S + D + E + F P
Sbjct: 1601 EQITGQIDKSTVKPKPQL---------------SHSSRLSSDLTR-----ETDEAAFEPD 1640
Query: 1474 FGLKQTDKVPSKTVAAKKGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPK 1533
+ ++ S++ + K + SS + K + +K E++++ + + GI + +
Sbjct: 1641 Y-----NESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSS 1695
Query: 1534 GKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKPKK 1569
++ SGS+ + SKK KK
Sbjct: 1696 PSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKK 1731
>gi|16445033 ACRC protein [Homo sapiens]
Length = 691
Score = 54.3 bits (129), Expect = 9e-07
Identities = 59/253 (23%), Positives = 98/253 (38%), Gaps = 38/253 (15%)
Query: 1368 DFSEEEDDDADDDDDDNNDLEELKVKASPITNDGEDEF-VPSDGLDKDEYTFSPGKSKAT 1426
D S++ DD+ DD+ D++D+ + K S + +D D+ VP D D E
Sbjct: 195 DSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEA 254
Query: 1427 PEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKT 1486
P+ S D ++ D S+D A DS+++ AS S D S
Sbjct: 255 PDDSSDDSEAPD-----------DSSDDSEAPDDSSDDSEASDDSSDDSEASDDS--SDD 301
Query: 1487 VAAKKGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGK---------GR 1537
A K VP+ K V NSD D E +P + +G+
Sbjct: 302 SEAPDDKSDDSDVPEDK---SDDSDVPDDNSD-DLEVPVPAEDLCNEGQIASDEEELVEA 357
Query: 1538 GAKKRKASGSENEGDYNPGRKTSKTTSKKPKKTSFDQDSDVDIFPSDFPTE---PPSLPR 1594
A + S++ G+ + G SK S D +++ ++ PTE P + +
Sbjct: 358 AAAVSQHDSSDDAGEQDLGENLSKPPS--------DPEANPEVSERKLPTEEEPAPVVEQ 409
Query: 1595 TGRARKEVKYFAE 1607
+G+ + + K E
Sbjct: 410 SGKRKSKTKTIVE 422
Score = 38.1 bits (87), Expect = 0.070
Identities = 54/249 (21%), Positives = 85/249 (34%), Gaps = 32/249 (12%)
Query: 1376 DADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKK 1435
D D+DDD+ NDLE P N + E P D D E P+ + D +
Sbjct: 125 DDDNDDDNGNDLE------VPDDNSDDSE-APDDNSDDSEAPDDNSDDSEAPDDNSDDSE 177
Query: 1436 SQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSA---SVFSPSFGLKQTDKVPSKTVAAKKG 1492
+ D + DDS D N +DS+ S S +D K+ +
Sbjct: 178 APD------------DNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVP 225
Query: 1493 KPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGD 1552
SSD P + + + + DS++ + P ++ S ++E
Sbjct: 226 DDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAS 285
Query: 1553 YNPGRKTSKTTSKKPKKTSFDQDSDVDIFPSDFPTEPPSLPRTGRARKEVKYFAE----- 1607
+ + + + D SD P D ++ +P EV AE
Sbjct: 286 DDSSDDSEASDDSSDDSEAPDDKSDDSDVPED-KSDDSDVPDDNSDDLEVPVPAEDLCNE 344
Query: 1608 ----SDEEE 1612
SDEEE
Sbjct: 345 GQIASDEEE 353
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 53.9 bits (128), Expect = 1e-06
Identities = 72/327 (22%), Positives = 112/327 (34%), Gaps = 34/327 (10%)
Query: 1308 RVRKTPTSSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTF 1367
+V + + P AKK KK+ SD E SE + E P +R K
Sbjct: 62 KVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAA 121
Query: 1368 DFSEEEDDDADDDDDDNNDLEELKV-----------KASPITNDGEDEFVPSDGLDKDEY 1416
SE + DDDD D ++ V KA P D S D+
Sbjct: 122 KASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPK 181
Query: 1417 TFSP--------GKSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSAS 1468
P ++KA P+ + K + S S S S D DS EE +A+
Sbjct: 182 NQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSD----DSEEEKAAA 237
Query: 1469 VFSPSFGLKQ-TDKVPSKTVAAKKGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPK 1527
+ KQ K P K K SS +QKK ++ S +P
Sbjct: 238 TPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSS---VPP 294
Query: 1528 KTTTPKGKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKPKKTSFDQDSDVDIFPSDFPT 1587
+ P K G + K + + + P + ++ + + ++ S T
Sbjct: 295 PSAPPPKKSLGTQPPKKAVEKQQ----PVESSEDSSDESDSSSEEEKKPPTKAVVSKATT 350
Query: 1588 EPPSLPRTGRARKEVKYFAESDEEEDD 1614
+PP + + + ++SD EDD
Sbjct: 351 KPPPAKKAAESSSD---SSDSDSSEDD 374
Score = 52.4 bits (124), Expect = 4e-06
Identities = 114/552 (20%), Positives = 192/552 (34%), Gaps = 91/552 (16%)
Query: 1099 ESDPVKAWKEAQEKAAEEDETQNQHDDSSSDSGTPSGPDFNYILNMSLWSLTKEKVEELI 1158
+ PV+ + Q KAA+ + + DS SDS + P N K K+ +
Sbjct: 142 KKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQ----------KPKITPVT 191
Query: 1159 KQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVESQEREDVLAGMSGKAIKGKVGKP 1218
+ K R +P + ++ S + E+ A + K K K
Sbjct: 192 VKAQTKAPPKP--ARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPK--KQ 247
Query: 1219 KVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKKKG---------------DLDTA 1263
V K ++ + ++ + + KK +K K G L T
Sbjct: 248 VVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQ 307
Query: 1264 AVKVEFDEEFSGAPVEGAGEEALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPSAKK 1323
K +++ PVE + + + ++ E+K+P T+ + ++ P AKK
Sbjct: 308 PPKKAVEKQ---QPVESSEDSS-------DESDSSSEEEKKPPTKAVVSKATTKPPPAKK 357
Query: 1324 VKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAA---------AERPKYTFDFSEE-- 1372
+ + S D SE D ++P ++S + A A PK ++
Sbjct: 358 AAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLL 417
Query: 1373 -EDDDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSL 1431
D+ +++++ EE K K T K KAT + +L
Sbjct: 418 TRKADSSSSEEESSSSEEEKTKKMVATT----------------------KPKATAKAAL 455
Query: 1432 HDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKV-----PSKT 1486
Q P S+ S DS S EE+ + S S K+ KV PSK
Sbjct: 456 SLPAKQ-------APQGSRDSSSDSDSSSSEEEEEKT--SKSAVKKKPQKVAGGAAPSKP 506
Query: 1487 VAAKKGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASG 1546
+AKKGK S + ++++ E + PK T + K K S
Sbjct: 507 ASAKKGKAESSNSSSSDDSSEEEE--EKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSE 564
Query: 1547 SENEGDYNPGRKTSKTTS-KKPKKTSFDQDSDVDIFPSDFPTEPPSLPRTGRARKEVKY- 1604
E E SK+ S KK K+ ++++ P + P+ + K
Sbjct: 565 EEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTPNTFPKRKKGEKRASSP 624
Query: 1605 FAESDEEEDDVD 1616
F EEE +VD
Sbjct: 625 FRRVREEEIEVD 636
Score = 33.1 bits (74), Expect = 2.2
Identities = 61/297 (20%), Positives = 106/297 (35%), Gaps = 22/297 (7%)
Query: 1107 KEAQEKAAEEDETQNQHDDSSSDSGTPSGPDFNYILNMSLWSLTKEK--VEELIKQRDAK 1164
K K A E + + DSS D PS P + + ++T + V+ +
Sbjct: 351 KPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPV 410
Query: 1165 GREVNDLKRKSPSDLWKEDLAAFVEELDK---VESQEREDVLAGMSGKAIKGKVGK---- 1217
G L RK+ S +E+ ++ EE K ++ + A +S A + G
Sbjct: 411 GGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSS 470
Query: 1218 --PKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKK-------KGDLDTAAVKVE 1268
+ EE S + P+ A A SK KK D ++ + E
Sbjct: 471 SDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEE 530
Query: 1269 FDEEFSGAPVEGAGEEALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRN 1328
+ G+P A + T ++ G K ++E + + S S KK K+
Sbjct: 531 EKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNE 590
Query: 1329 PWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDDNN 1385
+ E+ ++ P P+ R+ +R F EE+ + D DN+
Sbjct: 591 AAKEAETPQAKKIKLQTPNTFPK----RKKGEKRASSPFRRVREEEIEVDSRVADNS 643
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 53.9 bits (128), Expect = 1e-06
Identities = 115/585 (19%), Positives = 207/585 (35%), Gaps = 80/585 (13%)
Query: 1059 AESTKLNNQARFILEKIQGKITIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEDE 1118
+E+ K+N A + Q +IT R L R E + +K+ K++ E+ E E
Sbjct: 301 SEAAKVNTDA---MRSAQEEITEYRRQ-------LQARTTELEALKSTKDSLERQRSELE 350
Query: 1119 TQNQHDDSSSDSGTPSGPDFNYILNMSLWSLTKEKVEELIKQRDAKGREVN---DLKRKS 1175
++Q D +S +E I+Q DA+ R + +
Sbjct: 351 DRHQADIAS--------------------------YQEAIQQLDAELRNTKWEMAAQLRE 384
Query: 1176 PSDLWKEDLAAFVEELDKVESQEREDVLAGMSGKAIKGKVGKPKVKKLQLEETMPSPYGR 1235
DL +A +E + E E+ G G PK+ + + S
Sbjct: 385 YQDLLNVKMALDIEIAAYRKLLEGEECRIGFGPIPFSLPEGLPKIPSVSTHIKVKSEEKI 444
Query: 1236 RIIPE-----ITAMKADASKKLLKKKKGDLDTAAVKVEFDEEFSGAPVEGAGEEALTPSV 1290
+++ + + + ++ ++ + + A + E EE G E G E T S
Sbjct: 445 KVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSP 504
Query: 1291 PINKGPKPKREKKEPGTRVRKTPTSSGKP---------------SAKKVKKRNPWSDDES 1335
P + P++E K P K+P + P AK K S E+
Sbjct: 505 PAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEA 564
Query: 1336 KSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDDNNDLEELKVKAS 1395
KS E P + + A E K + E + ++ + E S
Sbjct: 565 KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAE----AKS 620
Query: 1396 PITNDGEDEFVPSDGLDKDEYTFSPGKSKA-TPEKSLH-DKKSQDFGNLFSFPSYSQKSE 1453
P+ + + P++ + E SP K +A +PEK+ +K+ P ++
Sbjct: 621 PVKEEAKS---PAE-VKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKS 676
Query: 1454 DDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVPKPKRAP--KQKKV 1511
+ AK E + + S +K+ K P K + K + S P+ ++P ++ K
Sbjct: 677 PEKAKSPVKAEAKSPEKAKS-PVKEEAKSPEKAKSPVKEEAKS---PEKAKSPVKEEAKT 732
Query: 1512 VEAVNSDSDSEFGIPKKTTTP-KGKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKPKKT 1570
E S E P+K +P K K K +A E +P K + K+
Sbjct: 733 PEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEE 792
Query: 1571 SFDQDSDVDIFPSDFPTEPPSLPRTGRARKEVKYFAESDEEEDDV 1615
+ D +P+ ++EVK + +E+ +V
Sbjct: 793 VKSPEKAKSPLKEDAKAPEKEIPK----KEEVKSPVKEEEKPQEV 833
Score = 53.9 bits (128), Expect = 1e-06
Identities = 102/480 (21%), Positives = 178/480 (37%), Gaps = 73/480 (15%)
Query: 1102 PVKAWKEAQEKAAEEDETQNQHDDSSSDSGTPSGPDFNYILNMSLWSLTKEKVEELIKQR 1161
P KA +E+A E ++ + + P+ S TKE+ + K +
Sbjct: 601 PEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPE-------KAKSPTKEEAKSPEKAK 653
Query: 1162 DAKGREVNDL-KRKSP-------SDLWKEDLAAFVEELDKVESQEREDVLAGMSGKA-IK 1212
+ E K KSP + K + A + +K +S +E+ + K+ +K
Sbjct: 654 SPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVK 713
Query: 1213 GKVGKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKKKGDLDTAAVKVEFDEE 1272
+ P+ K ++E +P + + A + +K K K D+ + K EE
Sbjct: 714 EEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEE 773
Query: 1273 FSGAPVEGAGEEALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSD 1332
+ +P + E+A +P + + K + K P K P K KK + ++P +
Sbjct: 774 -ARSPADKFPEKAKSP---VKEEVKSPEKAKSPLKEDAKAPE---KEIPKKEEVKSPVKE 826
Query: 1333 DESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDDNNDLEELKV 1392
+E E ++E P A PK T + + + ++A + +EE K
Sbjct: 827 EEKPQEVKVKE------PPKKAEEEKAPATPK-TEEKKDSKKEEAPKKEAPKPKVEEKKE 879
Query: 1393 KASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSYSQKS 1452
A + + E + DK K TPEK P+ +
Sbjct: 880 PAVEKPKESKVEAKKEEAEDK--------KKVPTPEKEA--------------PAKVEVK 917
Query: 1453 ED----DSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVPKPKRAPKQ 1508
ED + + E D A PS K +K K A +K + KP+ PK
Sbjct: 918 EDAKPKEKTEVAKKEPDDAKAKEPS---KPAEK---KEAAPEKKDTKEEKAKKPEEKPK- 970
Query: 1509 KKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKPK 1568
EA + D + K+ + PK A+K + S S ++ D P K ++ + K K
Sbjct: 971 ---TEAKAKEDDKT--LSKEPSKPK-----AEKAEKSSSTDQKDSKPPEKATEDKAAKGK 1020
Score = 43.5 bits (101), Expect = 0.002
Identities = 114/585 (19%), Positives = 200/585 (34%), Gaps = 80/585 (13%)
Query: 1063 KLNNQARFILEKIQGKITIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEDETQNQ 1122
K+ + + I K + KI + +S+K+ + ++ ++ E+ + E +EK A+E+E + +
Sbjct: 428 KIPSVSTHIKVKSEEKIKVVEKSEKETV-IVEEQTEETQVTEEVTEEEEKEAKEEEGKEE 486
Query: 1123 HDDSSSDSGTPSGPDFNYILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKE 1182
++ E EE K A+ + + KSP KE
Sbjct: 487 EGGEEEEA---------------------EGGEEETKSPPAEEAASPEKEAKSPV---KE 522
Query: 1183 DLAAFVEELDKVESQEREDVLAGMSGKAIKGKVGKPKVKKLQLEETMPSPYGRRIIPEIT 1242
+ + E +S E+E+ + +V P+ K +E SP + PE
Sbjct: 523 EAKSPAE----AKSPEKEEAKS-------PAEVKSPEKAKSPAKEEAKSPPEAKS-PEKE 570
Query: 1243 AMKADASKKLLKKKKGDLDTAAVKVEFDE--EFSGAPVEGAGEEALTPSVPINKGPKPKR 1300
K+ A K +K K A + E + +PV+ + P+ + K
Sbjct: 571 EAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPA 630
Query: 1301 EKKEPGTRVRKTPTSSGKPSAKKVK---KRNPWSDDESKSESDLEETEPVVIPRDSLLRR 1357
E K P K+PT S +K K K S +++KS E P S ++
Sbjct: 631 EVKSP--EKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPE--KAKSPVKA 686
Query: 1358 AAAERPKYTFDFSEEEDDDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKD--- 1414
A K EE + + + SP+ + + + ++
Sbjct: 687 EAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKS 746
Query: 1415 -EYTFSPGKSKA---------TPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEE 1464
E SP K+K TP K + F P + + AK E+
Sbjct: 747 PEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKED 806
Query: 1465 DSA---------SVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVPKPKR--------APK 1507
A V SP ++ +V K K + + PK + APK
Sbjct: 807 AKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPK 866
Query: 1508 QKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKP 1567
++ V + PK++ K K+K E E P + K +K
Sbjct: 867 KEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEA---PAKVEVKEDAKPK 923
Query: 1568 KKTSFDQDSDVDIFPSDFPTEPPSLPRTGRARKEVKYFAESDEEE 1612
+KT + D + P++P +K+ K EE
Sbjct: 924 EKTEVAKKEPDDAKAKE-PSKPAEKKEAAPEKKDTKEEKAKKPEE 967
>gi|59814411 hypothetical protein LOC253725 [Homo sapiens]
Length = 1318
Score = 52.4 bits (124), Expect = 4e-06
Identities = 75/294 (25%), Positives = 114/294 (38%), Gaps = 55/294 (18%)
Query: 1373 EDDDADDDDD-----DNNDLEELKVKASP-ITNDGEDEFVPSDGLDKDEYTFSP-GKSKA 1425
+DDD DDDDD + + KV+++ I D E + + E T S ++KA
Sbjct: 452 DDDDGDDDDDFFSAPHSKPSKTRKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKA 511
Query: 1426 TPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSP--SFGLKQTDKVP 1483
EK + S++ PS K++ S+EEDS +FS + LK +P
Sbjct: 512 RAEKKVTLSYSKNLK-----PSSETKTQKG---LFSDEEDSEDLFSSQSASNLKGASLLP 563
Query: 1484 SKT-------------------VAAKKGKPS--SDTVPKPKRAPKQKKVVEAVNSDSDSE 1522
K AAKK S + K K + KK A+ SD E
Sbjct: 564 GKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQREEKAKASELSKKKASALLFSSDEE 623
Query: 1523 FGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTS--------------KTTSKKPK 1568
+ IP T R + + SG+ + +KTS K + KK +
Sbjct: 624 WNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDKEDDLFAIAKDSQKKTQ 683
Query: 1569 KTSFDQDSDVDIFPSDFPTEPPSLPRTGRARK---EVKYFAESDEEEDDVDFAM 1619
+ S + DVD S F + P S+P + ++ E SDEEE + +
Sbjct: 684 RVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGV 737
Score = 40.8 bits (94), Expect = 0.011
Identities = 73/326 (22%), Positives = 119/326 (36%), Gaps = 53/326 (16%)
Query: 1333 DESKSESDLEETEPVVIPRDSLLRRAAAE-----RPKYTFDFSEEEDDDADDDDDDNNDL 1387
D K E D+E+ E P+ S A E + EE + L
Sbjct: 264 DSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAMGRVDEEPTTLPSGEAKPRKTL 323
Query: 1388 EELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPS 1447
+E K + +P ++ ++ F P D+D F G + K L D + ++ +LF
Sbjct: 324 KEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEE-SDLF---- 378
Query: 1448 YSQKSEDDSAKFDSNEEDSAS-------VFSPSFGLKQTDKVPSKTVAAKK--GKPSSDT 1498
++ S+D A EE S+S + S L TD + +V + K KP T
Sbjct: 379 -TEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSLKEPQKPEQPT 437
Query: 1499 VPKPKRAPKQKKVVEAVNSDSDSEF-----GIPKKTTTPKG--------KGRGAKKRKAS 1545
K P + + + D D +F P KT + +G K++ +
Sbjct: 438 PRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTADIFGDEEGDLFKEKAVA 497
Query: 1546 GSE---NEGDYNPGRKTSKTT------------SKKPKKTSFDQDSDVDIFPSDFPTE-- 1588
E ++ D N R K T +K K D++ D+F S +
Sbjct: 498 SPEATVSQTDENKARAEKKVTLSYSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASNLK 557
Query: 1589 -PPSLPRTGRARKEVKYFAESDEEED 1613
LP G+ V F + DEE++
Sbjct: 558 GASLLP--GKLPTSVSLFDDEDEEDN 581
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 52.0 bits (123), Expect = 5e-06
Identities = 73/330 (22%), Positives = 112/330 (33%), Gaps = 64/330 (19%)
Query: 1279 EGAGEEALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSE 1338
E + E+ PS P + ++KE G G+P K K+ DE + +
Sbjct: 905 EASEEKRPRPSTPAEEDEDDPEQEKEAG--------EPGRPGTKPPKR------DEERGK 950
Query: 1339 SDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDDNNDLEELKVKASPIT 1398
+ + R S + E ++E+DD +D++D++ + K
Sbjct: 951 TQGKH-------RKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEV 1003
Query: 1399 NDGEDEFVPSDGLDK-DEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSA 1457
+DGEDE SD K Y S G++ +T + S + S S S S +S+
Sbjct: 1004 SDGEDE--ESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESS 1061
Query: 1458 KFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVPKPKRAPKQKKVVEAVNS 1517
D EE+ + A P VP P AP + V E V
Sbjct: 1062 SEDEEEEE-------------------RPAALPSASPPPREVPVPTPAPVEVPVPERV-- 1100
Query: 1518 DSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKPKKTSFDQDSD 1577
G P TP + + R A +E P R
Sbjct: 1101 -----AGSP---VTPLPEQEASPARPAGPTEESPPSAPLRPPEPPAGPPAPAPR------ 1146
Query: 1578 VDIFPSDFPTEP-PSLPRTGRARKEVKYFA 1606
P + P+ P P LP + RK V + A
Sbjct: 1147 ----PDERPSSPIPLLPPPKKRRKTVSFSA 1172
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 [Homo
sapiens]
Length = 916
Score = 51.2 bits (121), Expect = 8e-06
Identities = 104/508 (20%), Positives = 193/508 (37%), Gaps = 52/508 (10%)
Query: 1084 RSKKDLI----QMLVQRGYESDPVKAWKEAQEKAAEEDETQNQHDDSSSDSGTPSGPDFN 1139
RS K+ I + L + E + V+ KE+ E+ + E ++ HD SS
Sbjct: 311 RSAKEEIAEYRRQLQSKSIELESVRGTKESLERQLSDIEERHNHDLSSYQDTIQQ---LE 367
Query: 1140 YILNMSLWSLTKE--KVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVESQ 1197
L + W + + + ++L+ + A E+ ++ + + + F +
Sbjct: 368 NELRGTKWEMARHLREYQDLLNVKMALDIEIAAYRKLLEGE--ETRFSTFAGSITGPLYT 425
Query: 1198 EREDVLAGMSGKAIKGKVGKPKVKKLQ------LEETMPSPYGRRIIPEITAMKADASKK 1251
R + +S K K KV PK+K +EET + +TA+ + +
Sbjct: 426 HRPPIT--ISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVS 483
Query: 1252 LLKKKKGDLDTAAVKVEFDEEFSGAPVEGAGEEALTPSVPINKGPKPKREKKEP------ 1305
+ ++KK + + E +EE A + + +A P V +G K + E +E
Sbjct: 484 MKEEKKEAAEEKEEEPEAEEEEVAA--KKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDE 541
Query: 1306 GTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKY 1365
G + + + K+ + E+++E++ EE E + A + +
Sbjct: 542 GAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEEL 601
Query: 1366 TFDFSEEEDDDADDDDDDNNDLEELK--VKASPITNDGEDEFV--PSDGLDKDEYTFSPG 1421
D E+ + A + E+ K V SP+ G+ P + K SP
Sbjct: 602 VADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPV 661
Query: 1422 KSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDK 1481
+ K S + + + P KS+ + K + EE+ K+ +
Sbjct: 662 EEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEE----------KEVKE 711
Query: 1482 VPSKTVAAKKGKPSSDTVPKPKRAP---KQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRG 1538
P + KK + D VP+ K+A K++ V E V + + K+T +GK
Sbjct: 712 APKEEKVEKKEEKPKD-VPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKE-EGKPLQ 769
Query: 1539 AKKRK-----ASGSENEGDYNPGRKTSK 1561
+K K GSE EG + G K S+
Sbjct: 770 QEKEKEKAGGEGGSEEEGS-DKGAKGSR 796
Score = 42.4 bits (98), Expect = 0.004
Identities = 62/263 (23%), Positives = 106/263 (40%), Gaps = 28/263 (10%)
Query: 1082 ENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEDETQNQHDDSSSDSGTPSGPDFNYI 1141
E +KK ++ E + K +E QE+ EEDE + SD G +
Sbjct: 505 EVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDE------GAKSDQAEEGGSEKEGS 558
Query: 1142 LNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVESQERED 1201
+ + E + +A+ +E ++ KS KE+L A KVE E+
Sbjct: 559 SEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADA----KVEKPEKAK 614
Query: 1202 VLAGMSGKAIKGKVGKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKK-KGDL 1260
S K GK V K +EE SP + + E K+ K +++K K +
Sbjct: 615 SPVPKSPVEEK---GKSPVPKSPVEEKGKSPVPKSPVEE--KGKSPVPKSPVEEKGKSPV 669
Query: 1261 DTAAVKVEFDEEFSGAPVEGAGEEALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPS 1320
+ V+ + +PVE A +A + KG + + E+KE V++ P
Sbjct: 670 SKSPVEEKAKSPVPKSPVEEAKSKA-----EVGKGEQKEEEEKE----VKEAPKEEKVEK 720
Query: 1321 AKKVKKRNPWSDDESKSESDLEE 1343
++ K P ++ K+ES ++E
Sbjct: 721 KEEKPKDVP---EKKKAESPVKE 740
Score = 32.7 bits (73), Expect = 2.9
Identities = 60/305 (19%), Positives = 107/305 (35%), Gaps = 26/305 (8%)
Query: 1318 KPSAKKVKKRNPWSDD---ESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEED 1374
K A K+K ++ + ++ E+K E + E E + L + E K + EEE
Sbjct: 440 KVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEP 499
Query: 1375 DDADDDDDDNNDLEELKVKASPI------TNDGEDEFVPSDGLDKDEYTFSPGKSKATPE 1428
+ + EE+ K SP+ + E E +G +++E KS E
Sbjct: 500 EAEE---------EEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEE 550
Query: 1429 KSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVA 1488
+K+ ++E + + ++ EE S K+ +K
Sbjct: 551 GG-SEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEK 609
Query: 1489 AKKGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSE 1548
+K K VPK K K V + + +PK KGK K +
Sbjct: 610 PEKAK---SPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGK 666
Query: 1549 NEGDYNPGRKTSKTTSKKPKKTSFDQDSDVDIFPSDFPTEPPSLPRTGRARKEVKYFAES 1608
+ +P + +K S PK + S ++ + E A KE K +
Sbjct: 667 SPVSKSPVEEKAK--SPVPKSPVEEAKSKAEVGKGEQKEEEEK--EVKEAPKEEKVEKKE 722
Query: 1609 DEEED 1613
++ +D
Sbjct: 723 EKPKD 727
>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapiens]
Length = 674
Score = 50.4 bits (119), Expect = 1e-05
Identities = 62/267 (23%), Positives = 103/267 (38%), Gaps = 32/267 (11%)
Query: 1086 KKDLIQMLVQRGY--ESDPVKAWKEAQEKAAEEDETQNQHDDSSSDSGTPSGPDFNYILN 1143
KK L + GY E V ++A EK EE+ + +S D P + +
Sbjct: 153 KKKLAEKKASIGYTYEDSTVAEVEKAAEKPEEEESAAEEESNSDEDEVIP-----DIDVE 207
Query: 1144 MSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVESQEREDVL 1203
+ + L +E+V +L KQ G D R D KE+ E + ++ E E +
Sbjct: 208 VDVDELNQEQVADLNKQATTYGMADGDFVRMLRKD--KEE----AEAIKHAKALEEEKAM 261
Query: 1204 AGMSGKAIKGKVGKPKVKKLQLEETMPSPYGRRIIPEITAMK---ADASKKLLKKKKGDL 1260
SG+ + + + + K+L+ + P Y RR P K +++S + + +
Sbjct: 262 --YSGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPT 319
Query: 1261 DTAAVKVEFDEEFSGAPVEGAGEEALT----------PSVPINKGPKPKREKKEPGTRVR 1310
K+ F F G+ E A A P+ P GP P R + R
Sbjct: 320 PGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRN----ASARR 375
Query: 1311 KTPTSSGKPSAKKVKKRNPWSDDESKS 1337
++ +SS SA + S S+S
Sbjct: 376 RSSSSSSSSSASRTSSSRSSSRSSSRS 402
Score = 32.3 bits (72), Expect = 3.8
Identities = 50/242 (20%), Positives = 87/242 (35%), Gaps = 49/242 (20%)
Query: 1359 AAERPKYTFDFSEEEDDDADD----DDDDNNDLEELKVKASPITNDGEDEFVPSDG---- 1410
AAE+P+ +EEE + +D D D D++EL + N + +DG
Sbjct: 178 AAEKPEEEESAAEEESNSDEDEVIPDIDVEVDVDELNQEQVADLNKQATTYGMADGDFVR 237
Query: 1411 ---LDKDEYTFSPGKSKATPEKSLHD-----KKSQDF------GNLFSFPSYSQKSEDDS 1456
DK+E EK+++ ++ ++F G S PSY+++
Sbjct: 238 MLRKDKEEAEAIKHAKALEEEKAMYSGRRSRRQRREFREKRLRGRKISPPSYARRDSPTY 297
Query: 1457 AKFDSNEEDSAS-----------------VFSPSFGLKQTDKVPSKTVAAKK----GKPS 1495
+ + +S+S F SFG + + AA GKP
Sbjct: 298 DPYKRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPP 357
Query: 1496 SDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNP 1555
+ P+P + S S S +T++ + R + + + G G Y
Sbjct: 358 AP--PQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGG----GYYRS 411
Query: 1556 GR 1557
GR
Sbjct: 412 GR 413
>gi|48255931 hepatoma-derived growth factor-related protein 2 isoform
1 [Homo sapiens]
Length = 671
Score = 49.7 bits (117), Expect = 2e-05
Identities = 77/324 (23%), Positives = 120/324 (37%), Gaps = 67/324 (20%)
Query: 1317 GKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDD 1376
GKP+ +K W + S P V DS E P + + + D
Sbjct: 69 GKPNKRKGFNEGLWEIQNNPHAS--YSAPPPVSSSDS-------EAP----EANPADGSD 115
Query: 1377 ADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKS 1436
AD+DD+D + V A+ ++ E + D D+ + + G + TP + K
Sbjct: 116 ADEDDEDRGVMAVTAVTATAASDRMESD------SDSDKSSDNSGLKRKTPALKMSVSKR 169
Query: 1437 QDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSS 1496
+ S+ D A +EE+++ S S D P K A
Sbjct: 170 ----------ARKASSDLDQASVSPSEEENSESSSESEKTSDQDFTPEKKAA-------- 211
Query: 1497 DTVPKPKRAP----KQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGD 1552
V P+R P K+KK A SDSDS+ P R A +S S ++ D
Sbjct: 212 --VRAPRRGPLGGRKKKKAPSA--SDSDSKADSDGAKPEPVAMARSASSSSSSSSSSDSD 267
Query: 1553 YN-----PGRKTS-----KTTSKKPK------KTSFDQDSDVDIFPSDFPTEPPSLPRTG 1596
+ GRK + K +KPK +S D DSD S++ + R
Sbjct: 268 VSVKKPPRGRKPAEKPLPKPRGRKPKPERPPSSSSSDSDSDEVDRISEWKRRDEARRREL 327
Query: 1597 RARK------EVKYFAESDEEEDD 1614
AR+ E++ E ++EE +
Sbjct: 328 EARRRREQEEELRRLREQEKEEKE 351
Score = 41.6 bits (96), Expect = 0.006
Identities = 75/344 (21%), Positives = 124/344 (36%), Gaps = 99/344 (28%)
Query: 1243 AMKADASKKLLKKKKGDLDTAAVKVEFDEEF-SGAPVEGAGEEALTPSVPINKGPKPKRE 1301
A+K SK+ +K DLD A+V +E S + E ++ TP E
Sbjct: 161 ALKMSVSKRA-RKASSDLDQASVSPSEEENSESSSESEKTSDQDFTP------------E 207
Query: 1302 KKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAE 1361
KK R+ P +K KK SD +SK++SD + EPV + R +
Sbjct: 208 KKAAVRAPRRGPLGG-----RKKKKAPSASDSDSKADSDGAKPEPVAMARSA-------- 254
Query: 1362 RPKYTFDFSEEEDDDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPG 1421
S + D D + VK P ++ +P P
Sbjct: 255 --------SSSSSSSSSSDSD-------VSVKKPPRGRKPAEKPLP-----------KPR 288
Query: 1422 KSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDK 1481
K PE+ P S S+ DS + D E K+ D+
Sbjct: 289 GRKPKPER----------------PPSSSSSDSDSDEVDRISE-----------WKRRDE 321
Query: 1482 VPSKTVAAKKGKPSSDTVPKPKRAPKQKKVVEAVNSD-SDSEFGI-------------PK 1527
+ + A++ + + + + + K++K +D ++E G P
Sbjct: 322 ARRRELEARRRREQEEELRRLREQEKEEKERRRERADRGEAERGSGGSSGDELREDDEPV 381
Query: 1528 KTTTPKGKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKPKKTS 1571
K KG+GRG +S SE E + + +K ++KKP+ +S
Sbjct: 382 KKRGRKGRGRGPP--SSSDSEPEAEL---EREAKKSAKKPQSSS 420
>gi|14249158 hepatoma-derived growth factor-related protein 2 isoform
2 [Homo sapiens]
Length = 670
Score = 49.7 bits (117), Expect = 2e-05
Identities = 77/324 (23%), Positives = 120/324 (37%), Gaps = 67/324 (20%)
Query: 1317 GKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDD 1376
GKP+ +K W + S P V DS E P + + + D
Sbjct: 69 GKPNKRKGFNEGLWEIQNNPHAS--YSAPPPVSSSDS-------EAP----EANPADGSD 115
Query: 1377 ADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKS 1436
AD+DD+D + V A+ ++ E + D D+ + + G + TP + K
Sbjct: 116 ADEDDEDRGVMAVTAVTATAASDRMESD------SDSDKSSDNSGLKRKTPALKMSVSKR 169
Query: 1437 QDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSS 1496
+ S+ D A +EE+++ S S D P K A
Sbjct: 170 ----------ARKASSDLDQASVSPSEEENSESSSESEKTSDQDFTPEKKAA-------- 211
Query: 1497 DTVPKPKRAP----KQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGD 1552
V P+R P K+KK A SDSDS+ P R A +S S ++ D
Sbjct: 212 --VRAPRRGPLGGRKKKKAPSA--SDSDSKADSDGAKPEPVAMARSASSSSSSSSSSDSD 267
Query: 1553 YN-----PGRKTS-----KTTSKKPK------KTSFDQDSDVDIFPSDFPTEPPSLPRTG 1596
+ GRK + K +KPK +S D DSD S++ + R
Sbjct: 268 VSVKKPPRGRKPAEKPLPKPRGRKPKPERPPSSSSSDSDSDEVDRISEWKRRDEARRREL 327
Query: 1597 RARK------EVKYFAESDEEEDD 1614
AR+ E++ E ++EE +
Sbjct: 328 EARRRREQEEELRRLREQEKEEKE 351
Score = 41.6 bits (96), Expect = 0.006
Identities = 75/344 (21%), Positives = 124/344 (36%), Gaps = 99/344 (28%)
Query: 1243 AMKADASKKLLKKKKGDLDTAAVKVEFDEEF-SGAPVEGAGEEALTPSVPINKGPKPKRE 1301
A+K SK+ +K DLD A+V +E S + E ++ TP E
Sbjct: 161 ALKMSVSKRA-RKASSDLDQASVSPSEEENSESSSESEKTSDQDFTP------------E 207
Query: 1302 KKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAE 1361
KK R+ P +K KK SD +SK++SD + EPV + R +
Sbjct: 208 KKAAVRAPRRGPLGG-----RKKKKAPSASDSDSKADSDGAKPEPVAMARSA-------- 254
Query: 1362 RPKYTFDFSEEEDDDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPG 1421
S + D D + VK P ++ +P P
Sbjct: 255 --------SSSSSSSSSSDSD-------VSVKKPPRGRKPAEKPLP-----------KPR 288
Query: 1422 KSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDK 1481
K PE+ P S S+ DS + D E K+ D+
Sbjct: 289 GRKPKPER----------------PPSSSSSDSDSDEVDRISE-----------WKRRDE 321
Query: 1482 VPSKTVAAKKGKPSSDTVPKPKRAPKQKKVVEAVNSD-SDSEFGI-------------PK 1527
+ + A++ + + + + + K++K +D ++E G P
Sbjct: 322 ARRRELEARRRREQEEELRRLREQEKEEKERRRERADRGEAERGSGGSSGDELREDDEPV 381
Query: 1528 KTTTPKGKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKPKKTS 1571
K KG+GRG +S SE E + + +K ++KKP+ +S
Sbjct: 382 KKRGRKGRGRGPP--SSSDSEPEAEL---EREAKKSAKKPQSSS 420
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 49.3 bits (116), Expect = 3e-05
Identities = 50/190 (26%), Positives = 84/190 (44%), Gaps = 26/190 (13%)
Query: 1283 EEALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPSAKKVK-KRNPWSDDESKSESDL 1341
++ L PS +++ + + ++E + TP K K V +R P E S +
Sbjct: 978 QKRLRPSTSVDE--EDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEE 1035
Query: 1342 EETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDDNNDLEELKVKASPITNDG 1401
+E E + ++S AE EE+++ DDDDDD++D +E + ND
Sbjct: 1036 DEKESLSEEQESTEEEEEAE----------EEEEEEDDDDDDSDDRDESE-------NDD 1078
Query: 1402 EDEFV-----PSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDF-GNLFSFPSYSQKSEDD 1455
ED + +G +E T S SKA S +S +F + S PS S+ E+
Sbjct: 1079 EDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEV 1138
Query: 1456 SAKFDSNEED 1465
A+ + EE+
Sbjct: 1139 VAREEEEEEE 1148
Score = 43.5 bits (101), Expect = 0.002
Identities = 58/258 (22%), Positives = 97/258 (37%), Gaps = 46/258 (17%)
Query: 1108 EAQEKAAEEDETQNQHDDSSSDSGTPSGPDFNYILNMS------------LWSLTKEKVE 1155
E +E+A EE+E ++ DD S D D + L+ + S+ K E
Sbjct: 1049 EEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAE 1108
Query: 1156 ELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVESQEREDVLAGMSGKAIKGKV 1215
++ E SPS E+ EE E +E E+++A
Sbjct: 1109 ATSSSESSESSEFESSSESSPSSSEDEEEVVAREE---EEEEEEEEMVA----------- 1154
Query: 1216 GKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKKKGDLDTAAVKVEFDEEFSG 1275
EE+M S PE + D + L +D+ ++ E D E
Sbjct: 1155 ----------EESMASAG-----PE--DFEQDGEEAALAPGAPAVDSLGMEEEVDIETEA 1197
Query: 1276 APVEGAGEEALTPSVPIN-KGPKPKRE-KKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDD 1333
E P +P+ + P RE +EPG S +P AK+V+ R P S +
Sbjct: 1198 VAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPE 1257
Query: 1334 ES-KSESDLEETEPVVIP 1350
+ + + ++E P+++P
Sbjct: 1258 RAPEHDLEVEPEPPMMLP 1275
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 49.3 bits (116), Expect = 3e-05
Identities = 73/324 (22%), Positives = 126/324 (38%), Gaps = 49/324 (15%)
Query: 1325 KKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDDN 1384
KK+ S+D +K + DL+ + + A + P+ + ++E D D+DD
Sbjct: 3 KKQKNKSEDSTKDDIDLDALAAEIEGAGA----AKEQEPQKSKGKKKKEKKKQDFDEDDI 58
Query: 1385 -NDLEELKVKASPI-----------TNDGEDEFVPSD----GLDKDEYTFSPGKSKATPE 1428
+LEEL ++A I T + E+EF D G + +F S+ +
Sbjct: 59 LKELEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELED 118
Query: 1429 KSLHDKK-----------SQDFGNLFSFPSYSQ-KSEDDSAKFDSNEEDSASVFSPSFGL 1476
K KK S D + P ++ K++ + K+D +EED + S +
Sbjct: 119 KDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDN----SKKI 174
Query: 1477 KQTDKVPSKTVAAKKGKPSSDTVPKPKRAPKQKK-----VVEAVNSDSDSEFGIPKKTTT 1531
K+ ++ S + + G S + + K K +K +E+ N D D+ F I KT
Sbjct: 175 KERSRINS---SGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKI--KTVA 229
Query: 1532 PKGKGRGAKKRKASGSENEGDYNPGRKTSKTTSKK--PKKTSFDQDSDVDIFPSDFPTEP 1589
K + ++RK E K T KK K+ + + + S +
Sbjct: 230 QKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDT 289
Query: 1590 PSLPRTGRARKEVKYFAESDEEED 1613
+P + E AE D E D
Sbjct: 290 GVIP-ASEEKAETPTAAEDDNEGD 312
Score = 39.3 bits (90), Expect = 0.031
Identities = 96/486 (19%), Positives = 180/486 (37%), Gaps = 55/486 (11%)
Query: 1063 KLNNQARFILEKIQGKITIENRSKK----DLIQMLVQRGYESDPVKAWKEAQEKAAEED- 1117
K +A+ +K G E+ SKK I + G ESD ++ Q+K +
Sbjct: 149 KAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKP 208
Query: 1118 ----ETQNQHDDSSSDSGTPSGPDFNYILNMSLWSLTKEKVEELIKQRDAKGREVNDLKR 1173
E+ N+ DD+S T + EK E K+RD + ++ LK
Sbjct: 209 GPNIESGNEDDDASFKIKTVA-------------QKKAEKKERERKKRDEEKAKLRKLKE 255
Query: 1174 KSPSDLWKEDLAAFVEELDKVESQEREDVLAGMSG--KAIKGKVGKPKVKKLQLEETMPS 1231
K + K+D + E K E + + + +G A + K P + E
Sbjct: 256 KEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNE----- 310
Query: 1232 PYGRRIIPEITAMKADASKKLLKKKKGD-------LDTAAVKVEFDEEFSGAPVEGAGEE 1284
G + + K + +K +KKKG + A K++ +EE E +
Sbjct: 311 --GDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKR 368
Query: 1285 ALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSESDLEET 1344
+ + ++EK+E + K K K + K + +++ L +
Sbjct: 369 LEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQA 428
Query: 1345 EPVVIP-RDSLLRRAAAERPKYTFDFSEE-EDDDADDDDDDNNDLEEL------KVKASP 1396
+ V +P +DSL ++ K ++ E + + + +E + K + P
Sbjct: 429 QGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPP 488
Query: 1397 ITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLH--------DKKSQDFGNLFSFPSY 1448
E+E GLD E S +++ +H +++ ++ S
Sbjct: 489 PVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESE 548
Query: 1449 SQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVPKPKRA-PK 1507
++ E+ ++ +E+ V K DK PSK +++ S D K +RA K
Sbjct: 549 EEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDK 608
Query: 1508 QKKVVE 1513
K+ +E
Sbjct: 609 AKRRIE 614
>gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform a
[Homo sapiens]
Length = 845
Score = 48.9 bits (115), Expect = 4e-05
Identities = 70/290 (24%), Positives = 104/290 (35%), Gaps = 49/290 (16%)
Query: 1298 PKREKKEP---GTRVRKTPTSSGKPSAKKVKK-RNPWSDDESKSESDLEETEPVVIPRDS 1353
PK++ EP G +P+ KK KK + + ++ + + E E V+ ++
Sbjct: 5 PKQQPPEPEWIGDGESTSPSDKVVKKGKKDKKIKKTFFEELAVEDKQAGEEEKVLKEKEQ 64
Query: 1354 LLRRAAAERPKYTFDFSEEEDDDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDK 1413
++ ++ K D DDD ++ +E LK K S T+D EDE
Sbjct: 65 QQQQQQQQQKKKRDTRKGRRKKDVDDDGEEKELMERLK-KLSVPTSDEEDE--------- 114
Query: 1414 DEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPS 1473
P K GN+F+ Q E+ EE+ P+
Sbjct: 115 ------------VPAPKPRGGKKTKGGNVFAALIQDQSEEE--------EEEEKHPPKPA 154
Query: 1474 FGLKQ--TDKVPSKTVAAKKGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTT 1531
K V + A KGK + K K P Q K N + D E I K+
Sbjct: 155 KPEKNRINKAVSEEQQPALKGKKGKEEKSKGKAKP-QNKFAALDNEEEDKEEEIIKEKEP 213
Query: 1532 PK-GKGRGAKKRKASGSENEGDY-----------NPGRKTSKTTSKKPKK 1569
PK GK + K + S E EG+ +P SK KK KK
Sbjct: 214 PKQGKEKAKKAEQGSEEEGEGEEEEEEGGESKADDPYAHLSKKEKKKLKK 263
Score = 33.5 bits (75), Expect = 1.7
Identities = 51/239 (21%), Positives = 92/239 (38%), Gaps = 40/239 (16%)
Query: 1149 LTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVESQEREDVLAGMSG 1208
+ K EEL + G E LK K ++ ++ D + + ++DV
Sbjct: 37 IKKTFFEELAVEDKQAGEEEKVLKEKEQQQQQQQQQQK--KKRDTRKGRRKKDVDDDGEE 94
Query: 1209 KAIKGKVGKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKKKGDLDTAAVKVE 1268
K + ++ K V E+ +P+P K KK K G++ A ++ +
Sbjct: 95 KELMERLKKLSVPTSDEEDEVPAP------------KPRGGKKT---KGGNVFAALIQDQ 139
Query: 1269 FDEEFSGAPVEGAGEEALTPSVPI----NKGPKPKREKKEPGTRVRKTPTSSGKPSAKKV 1324
+EE EE P P N+ K E+++P + +K K AK
Sbjct: 140 SEEE---------EEEEKHPPKPAKPEKNRINKAVSEEQQPALKGKKGKEEKSKGKAKPQ 190
Query: 1325 KKRNPW-SDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDD 1382
K +++E K E ++E EP + E+ K SEEE + +++++
Sbjct: 191 NKFAALDNEEEDKEEEIIKEKEPP---------KQGKEKAKKAEQGSEEEGEGEEEEEE 240
>gi|38788333 remodeling and spacing factor 1 [Homo sapiens]
Length = 1441
Score = 48.5 bits (114), Expect = 5e-05
Identities = 65/286 (22%), Positives = 109/286 (38%), Gaps = 42/286 (14%)
Query: 1356 RRAAAERPKYTFDFSEEEDDDADDDDDDNNDLEELKVKASPITNDGEDEFVPSD------ 1409
R AAA R K D D+D + D+ +E K I++ +DEFV SD
Sbjct: 1079 RAAAARRKKRR----RLNDLDSDSNLDEEESEDEFK-----ISDGSQDEFVVSDENPDES 1129
Query: 1410 -----GLDKDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEE 1464
D + F + + P + + + P +D+ + + N
Sbjct: 1130 EEDPPSNDDSDTDFCSRRLRRHPSRPMRQSRRL----RRKTPKKKYSDDDEEEESEENSR 1185
Query: 1465 DSASVFSPSFG-------LKQTDKVPSKTVAAKKGKPSSDTVPKPKRAPKQKKVVEAVNS 1517
DS S FS F +++ + + + K+ S + +R + ++V + S
Sbjct: 1186 DSESDFSDDFSDDFVETRRRRSRRNQKRQINYKEDSESDGSQKSLRRGKEIRRVHKRRLS 1245
Query: 1518 DSDSEFGIPKKTT----TPKGKGRGAKKRKASGSE-NEGDYNPGRKTSKTTSKKPKKTSF 1572
S+SE K + K R +KR S E +E D + K + K+ +
Sbjct: 1246 SSESEESYLSKNSEDDELAKESKRSVRKRGRSTDEYSEADEEEEEEEGKPSRKRLHRIET 1305
Query: 1573 DQDSDVDIFPSDF-----PTEPPSLPRTGRARKEVKYFAESDEEED 1613
D++ D D ++P LP + K+ Y ESDEEED
Sbjct: 1306 DEEESCDNAHGDANQPARDSQPRVLPSEQESTKK-PYRIESDEEED 1350
>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 1 [Homo sapiens]
Length = 559
Score = 48.1 bits (113), Expect = 7e-05
Identities = 71/330 (21%), Positives = 125/330 (37%), Gaps = 48/330 (14%)
Query: 1286 LTPSVPINKGPKPKREKKEPGTR-VRKTPTSSGKP-SAKKVKKRNPWSDDESKSESDLEE 1343
+ P++P++ PK+ K G++ K + + KP K + P D ESKS S E
Sbjct: 160 MLPTIPLSAFSDPKKTKPSHGSKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELE 219
Query: 1344 TEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDDNNDLEELKVKA-SPITNDGE 1402
E +D+ + PK E+ + L+E K+++ SP
Sbjct: 220 REQAKSSKDTSRKLGEGRLPK-----EEKAPPPKAAFKEPKMALKETKLESTSPKGGPPP 274
Query: 1403 DEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSN 1462
P K T K A +K K S+ SA S
Sbjct: 275 PPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSR------------------SAPGTSP 316
Query: 1463 EEDSASVFSPSFGLKQTDKVPSKTVAAKKG-KPSSDTVPKPKRAPKQKKVVEAVNSDSDS 1521
S+S FS DK P+K ++ +G K +++ P R K+ VE NS+ ++
Sbjct: 317 RTSSSSSFS--------DKKPAKDKSSTRGEKVKAESEP---REAKKALEVEESNSEDEA 365
Query: 1522 EFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKPKKTSFDQDSDVDIF 1581
F ++P + +S S ++ D+ P + S+ + + ++SD D
Sbjct: 366 SFKSESAQSSP------SNSSSSSDSSSDSDFEPSQNHSQGPLRSMVEDLQSEESDED-- 417
Query: 1582 PSDFPTEPPSLPRTGRARKEVKYFAESDEE 1611
D + + +T R F++S+ +
Sbjct: 418 --DSSSGEEAAGKTNPGRDSRLSFSDSESD 445
>gi|54124343 hypothetical protein LOC387680 [Homo sapiens]
Length = 1341
Score = 48.1 bits (113), Expect = 7e-05
Identities = 72/292 (24%), Positives = 107/292 (36%), Gaps = 50/292 (17%)
Query: 1374 DDDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDG-LDKDEYTFSPGK--SKATPEKS 1430
DDD DDDDD K + D F +G L K++ SP S+ K+
Sbjct: 452 DDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKA 511
Query: 1431 LHDKKSQDFGNLFSFPSYSQKSEDDSAK-FDSNEEDSASVFSPSFG--LKQTDKVPSKT- 1486
+KK L S + SE + K S+EEDS +FS LK +P K
Sbjct: 512 RAEKKV----TLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLP 567
Query: 1487 ------------------VAAKKG----KPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFG 1524
AAKK + + K K+K +SD + ++
Sbjct: 568 TLVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWN 627
Query: 1525 IPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTS--------------KTTSKKPKKT 1570
IP T R + + SG+ + +KTS K + KK ++
Sbjct: 628 IPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRV 687
Query: 1571 SFDQDSDVDIFPSDFPTEPPSLPRTGRARK---EVKYFAESDEEEDDVDFAM 1619
S + DVD S F + P S+P + ++ E SDEEE + +
Sbjct: 688 SLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGV 739
Score = 40.0 bits (92), Expect = 0.018
Identities = 72/327 (22%), Positives = 117/327 (35%), Gaps = 55/327 (16%)
Query: 1333 DESKSESDLEETEPVVIPRDSLLRRAAAE-----RPKYTFDFSEEEDDDADDDDDDNNDL 1387
D K E D+E+ E P+ S A E + EE + L
Sbjct: 264 DSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTL 323
Query: 1388 EELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPS 1447
+E K + +P ++ ++ F P D+D F G + K L D + ++ +LF
Sbjct: 324 KEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEE-SDLF---- 378
Query: 1448 YSQKSEDDSAKFDSNEEDSAS-------VFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVP 1500
++ +D A EE S+S + S L TD + +V + K +P P
Sbjct: 379 -TEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMK-EPQKPEQP 436
Query: 1501 KPKRAPKQKKVV----EAVNSDSDSEFGIPKKTTTPKGKGRGAK-----------KRKAS 1545
P+++P + D D F P + GK + K KA
Sbjct: 437 TPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAV 496
Query: 1546 GSE----NEGDYNPGRKTSKTT------------SKKPKKTSFDQDSDVDIFPSDFPTE- 1588
S ++ D N R K T +K K D++ D+F S ++
Sbjct: 497 ASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKL 556
Query: 1589 --PPSLPRTGRARKEVKYFAESDEEED 1613
LP G+ V F + DEE++
Sbjct: 557 KGASLLP--GKLPTLVSLFDDEDEEDN 581
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 48.1 bits (113), Expect = 7e-05
Identities = 101/482 (20%), Positives = 176/482 (36%), Gaps = 44/482 (9%)
Query: 1151 KEKVEELIK-QRDAKGREVNDLKRKSPSD-LWKEDLAAFVEELDKVESQEREDVLAGMSG 1208
KEKV E K ++ A +E + K K + L KE A E K E + +++V G
Sbjct: 171 KEKVREKEKPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAE--KSEEKTKKEV---KGG 225
Query: 1209 KAIKGKVGKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKKKGDLDTAAVKVE 1268
K K K KVK++Q + P K D K + K + A +
Sbjct: 226 KQEKVKQTAAKVKEVQKTPSKPKE------------KEDKEKAAVSKHEQKDQYAFCRYM 273
Query: 1269 FDEEFSGAPVEGAGEEALTPSVPINKGPKP----------KREKKEPGTRVRKTPTSSGK 1318
D F ++ A+ P +P + +P + EKK+ +V K
Sbjct: 274 IDI-FVHGDLKPGQSPAIPPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEK 332
Query: 1319 PSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDAD 1378
KK ++ D E K ET+ + + +AAA++ + D S++ A+
Sbjct: 333 EDIKKKSEKETAIDVEKKEPGKASETKQGTV---KIAAQAAAKKDEKKED-SKKTKKPAE 388
Query: 1379 DDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATP-EKSLHDKKSQ 1437
+ E+ + P + ++ VPSD K + + + A +K++ KK +
Sbjct: 389 VEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEE 448
Query: 1438 DFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSD 1497
+KS S+ E LK +K P K K +
Sbjct: 449 KTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLK--EKEPETKKDEKMSKAGKE 506
Query: 1498 TVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGR 1557
PKP + +K+ +++ I +K K +K + G E +
Sbjct: 507 VKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEKVLKQVK 566
Query: 1558 KTS--KTTSKKPKKTSFDQDSDVDIFPSDFPTEPP----SLPRTGRARKEVKYFAESDEE 1611
+ KT KP K + ++ + +D P P + +G+ + E+ ES E+
Sbjct: 567 AVTIEKTAKPKPTKKAEHREREPPSIKTDKPKPTPKGTSEVTESGKKKTEISE-KESKEK 625
Query: 1612 ED 1613
D
Sbjct: 626 AD 627
Score = 37.7 bits (86), Expect = 0.091
Identities = 88/420 (20%), Positives = 149/420 (35%), Gaps = 67/420 (15%)
Query: 1148 SLTKEKVEELIKQRDAKGREVNDLKRKSPSDL--WKEDLAAFVEELDKVESQEREDVLAG 1205
S TK+K +E IK++ K + D+++K P K+ + + +++ED
Sbjct: 325 SETKKKEKEDIKKKSEKETAI-DVEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKT 383
Query: 1206 MSGKAIKGKVGKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKKKGDLDTAAV 1265
++ GK + KK + E SP +P +KA +
Sbjct: 384 KKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAK------------- 430
Query: 1266 KVEFDEEFSGAPVEGAGEEALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPSAKKVK 1325
E G ++ +VP G K ++ K +RK SGK S+ +K
Sbjct: 431 -------------EEIGAVSIKKAVP---GKKEEKTTKTVEQEIRKE--KSGKTSSI-LK 471
Query: 1326 KRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAE---RPKYTFDFSEEEDDDADDDDD 1382
+ P E K + L+E EP +D + +A E +P EE+ +
Sbjct: 472 DKEPIKGKEEKVPASLKEKEPET-KKDEKMSKAGKEVKPKPPQLQGKKEEKPE------- 523
Query: 1383 DNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFGNL 1442
++K +A P + E + + K E T S GK + EK L K+
Sbjct: 524 -----PQIKKEAKPAIS--EKVQIHKQDIVKPEKTVSHGKPE---EKVLKQVKA------ 567
Query: 1443 FSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVPKP 1502
+ ++ A+ E S P K T +V T + KK S+ K
Sbjct: 568 VTIEKTAKPKPTKKAEHREREPPSIKTDKPKPTPKGTSEV---TESGKKKTEISEKESKE 624
Query: 1503 KRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEG--DYNPGRKTS 1560
K K + + + K P + + AS EG D +P ++ S
Sbjct: 625 KADMKHLREEKVSTRKESLQLHNVTKAEKPARVSKDVEDVPASKKAKEGTEDVSPTKQKS 684
Score = 37.0 bits (84), Expect = 0.16
Identities = 58/294 (19%), Positives = 110/294 (37%), Gaps = 38/294 (12%)
Query: 1354 LLRRAAAERPKYTFDF---------SEEEDDDADDDDDDNNDLEELKVKASPITNDGEDE 1404
L+R A E + + F SE+E+DD D+D D +++E ++ I D ++
Sbjct: 91 LVRDAMEETTDWIYGFFSLLSDIISSEDEEDDDGDEDTDKGEIDEPPLRKKEIHKDKTEK 150
Query: 1405 FVPSD--------------GLDKDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSYSQ 1450
+ G +K P K KAT ++ + K+ + L ++
Sbjct: 151 QEKPERKIQTKVTHKEKEKGKEKVREKEKPEK-KATHKEKIEKKEKPETKTLAKEQKKAK 209
Query: 1451 KSE--DDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVPKPKRAPKQ 1508
+E ++ K + V + +K+ K PSK K K + K K
Sbjct: 210 TAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKP----KEKEDKEKAAVSKHEQKD 265
Query: 1509 K----KVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGS--ENEGDYNPGRKTSKT 1562
+ + + + D + G P + ++ AS + E EG+ K +
Sbjct: 266 QYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTS 325
Query: 1563 TSKKPKKTSFDQDSDVDIFPSDFPTEPPSLPRT--GRARKEVKYFAESDEEEDD 1614
+KK +K + S+ + EP T G + + A+ DE+++D
Sbjct: 326 ETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKKED 379
>gi|154090959 hypothetical protein LOC55747 [Homo sapiens]
Length = 1253
Score = 48.1 bits (113), Expect = 7e-05
Identities = 72/292 (24%), Positives = 107/292 (36%), Gaps = 50/292 (17%)
Query: 1374 DDDADDDDDDNNDLEELKVKASPITNDGEDEFVPSDG-LDKDEYTFSPGK--SKATPEKS 1430
DDD DDDDD K + D F +G L K++ SP S+ K+
Sbjct: 364 DDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKA 423
Query: 1431 LHDKKSQDFGNLFSFPSYSQKSEDDSAK-FDSNEEDSASVFSPSFG--LKQTDKVPSKT- 1486
+KK L S + SE + K S+EEDS +FS LK +P K
Sbjct: 424 RAEKKV----TLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLP 479
Query: 1487 ------------------VAAKKG----KPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFG 1524
AAKK + + K K+K +SD + ++
Sbjct: 480 TSVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWN 539
Query: 1525 IPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTS--------------KTTSKKPKKT 1570
IP T R + + SG+ + +KTS K + KK ++
Sbjct: 540 IPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRV 599
Query: 1571 SFDQDSDVDIFPSDFPTEPPSLPRTGRARK---EVKYFAESDEEEDDVDFAM 1619
S + DVD S F + P S+P + ++ E SDEEE + +
Sbjct: 600 SLLFEDDVDSRGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGV 651
Score = 41.2 bits (95), Expect = 0.008
Identities = 72/327 (22%), Positives = 117/327 (35%), Gaps = 55/327 (16%)
Query: 1333 DESKSESDLEETEPVVIPRDSLLRRAAAE-----RPKYTFDFSEEEDDDADDDDDDNNDL 1387
D K E D+E+ E P+ S A E + EE + L
Sbjct: 176 DSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTL 235
Query: 1388 EELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPS 1447
+E K + +P ++ ++ F P D+D F G + K L D + ++ +LF
Sbjct: 236 KEKKERRTPSDDEEDNLFTPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEE-SDLF---- 290
Query: 1448 YSQKSEDDSAKFDSNEEDSAS-------VFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVP 1500
++ +D A EE S+S + S L TD + +V + K +P P
Sbjct: 291 -TEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMK-EPQKPEQP 348
Query: 1501 KPKRAPKQKKVV----EAVNSDSDSEFGIPKKTTTPKGKGRGAK-----------KRKAS 1545
P+++P + D D F P + GK + K KA
Sbjct: 349 TPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAV 408
Query: 1546 GSE----NEGDYNPGRKTSKTT------------SKKPKKTSFDQDSDVDIFPSDFPTE- 1588
S ++ D N R K T +K K D++ D+F S ++
Sbjct: 409 ASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKL 468
Query: 1589 --PPSLPRTGRARKEVKYFAESDEEED 1613
LP G+ V F + DEE++
Sbjct: 469 KGASLLP--GKLPTSVSLFDDEDEEDN 493
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 [Homo
sapiens]
Length = 540
Score = 47.8 bits (112), Expect = 9e-05
Identities = 82/380 (21%), Positives = 145/380 (38%), Gaps = 39/380 (10%)
Query: 1206 MSGKAIKGKVGKPKVKKLQ------LEETMPSPYGRRIIPEITAMKADASKKLLKKKKGD 1259
+S K K KV PK+K +EET + +TA+ + + + ++KK
Sbjct: 56 ISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEA 115
Query: 1260 LDTAAVKVEFDEEFSGAPVEGAGEEALTPSVPINKGPKPKREKKEP------GTRVRKTP 1313
+ + E +EE A + + +A P V +G K + E +E G + +
Sbjct: 116 AEEKEEEPEAEEEEVAA--KKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAE 173
Query: 1314 TSSGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEE 1373
+ K+ + E+++E++ EE E + A + + D E+
Sbjct: 174 EGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEK 233
Query: 1374 DDDADDDDDDNNDLEELK--VKASPITNDGEDEFV--PSDGLDKDEYTFSPGKSKATPEK 1429
+ A + E+ K V SP+ G+ P + K SP + K
Sbjct: 234 PEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV 293
Query: 1430 SLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAA 1489
S + + + P KS+ + K + EE+ K+ + P +
Sbjct: 294 SKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEE----------KEVKEAPKEEKVE 343
Query: 1490 KKGKPSSDTVPKPKRAP---KQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRK--- 1543
KK + D VP+ K+A K++ V E V + + K+T +GK +K K
Sbjct: 344 KKEEKPKD-VPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKE-EGKPLQQEKEKEKA 401
Query: 1544 --ASGSENEGDYNPGRKTSK 1561
GSE EG + G K S+
Sbjct: 402 GGEGGSEEEGS-DKGAKGSR 420
Score = 42.4 bits (98), Expect = 0.004
Identities = 62/263 (23%), Positives = 106/263 (40%), Gaps = 28/263 (10%)
Query: 1082 ENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEDETQNQHDDSSSDSGTPSGPDFNYI 1141
E +KK ++ E + K +E QE+ EEDE + SD G +
Sbjct: 129 EVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDE------GAKSDQAEEGGSEKEGS 182
Query: 1142 LNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVESQERED 1201
+ + E + +A+ +E ++ KS KE+L A KVE E+
Sbjct: 183 SEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADA----KVEKPEKAK 238
Query: 1202 VLAGMSGKAIKGKVGKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKK-KGDL 1260
S K GK V K +EE SP + + E K+ K +++K K +
Sbjct: 239 SPVPKSPVEEK---GKSPVPKSPVEEKGKSPVPKSPVEE--KGKSPVPKSPVEEKGKSPV 293
Query: 1261 DTAAVKVEFDEEFSGAPVEGAGEEALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPS 1320
+ V+ + +PVE A +A + KG + + E+KE V++ P
Sbjct: 294 SKSPVEEKAKSPVPKSPVEEAKSKA-----EVGKGEQKEEEEKE----VKEAPKEEKVEK 344
Query: 1321 AKKVKKRNPWSDDESKSESDLEE 1343
++ K P ++ K+ES ++E
Sbjct: 345 KEEKPKDVP---EKKKAESPVKE 364
Score = 32.7 bits (73), Expect = 2.9
Identities = 60/305 (19%), Positives = 107/305 (35%), Gaps = 26/305 (8%)
Query: 1318 KPSAKKVKKRNPWSDD---ESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEED 1374
K A K+K ++ + ++ E+K E + E E + L + E K + EEE
Sbjct: 64 KVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEP 123
Query: 1375 DDADDDDDDNNDLEELKVKASPI------TNDGEDEFVPSDGLDKDEYTFSPGKSKATPE 1428
+ + EE+ K SP+ + E E +G +++E KS E
Sbjct: 124 EAEE---------EEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEE 174
Query: 1429 KSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVA 1488
+K+ ++E + + ++ EE S K+ +K
Sbjct: 175 GG-SEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEK 233
Query: 1489 AKKGKPSSDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSE 1548
+K K VPK K K V + + +PK KGK K +
Sbjct: 234 PEKAK---SPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGK 290
Query: 1549 NEGDYNPGRKTSKTTSKKPKKTSFDQDSDVDIFPSDFPTEPPSLPRTGRARKEVKYFAES 1608
+ +P + +K S PK + S ++ + E A KE K +
Sbjct: 291 SPVSKSPVEEKAK--SPVPKSPVEEAKSKAEVGKGEQKEEEEK--EVKEAPKEEKVEKKE 346
Query: 1609 DEEED 1613
++ +D
Sbjct: 347 EKPKD 351
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 47.8 bits (112), Expect = 9e-05
Identities = 89/420 (21%), Positives = 162/420 (38%), Gaps = 69/420 (16%)
Query: 1231 SPYGRRIIPEITAMKADASKKLLKKKKGDLDTAAVKVEFDEEFSGAPVEGAGEEALTPSV 1290
+P ++I+ E T + +A K LK + + K + E E + +V
Sbjct: 141 NPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSK---------SSSETNPESQNSKTV 191
Query: 1291 PINKGPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDD---ESKSESDLE----- 1342
N K K++ K ++ T K + KK KR+ S+D E SE+ L
Sbjct: 192 SKNCSQKDKKDSKN--SKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLM 249
Query: 1343 ---ETEPVVIPRDSLLRRAAAERPK-YTFDFSE----------EEDDDADDDDDDNNDLE 1388
+++ I D+ LR + K Y+ +++ ++ DA+ +D + +
Sbjct: 250 LVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKD 309
Query: 1389 ELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSY 1448
KVK + + D + + V D D + G SK + + DKK
Sbjct: 310 SKKVKKN-VKKDDKKKDVKKDTESTDAES---GDSKDERKDTKKDKKKLK---------- 355
Query: 1449 SQKSEDDSAKF----DSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVPKPKR 1504
+ D+ K+ D+ D+ + S LK+ K K AKK S+D+
Sbjct: 356 KDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDS------ 409
Query: 1505 APKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTSKTTS 1564
+ +E+ S D + T K + ++ + SE +GD G+K K
Sbjct: 410 ----ESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGK 465
Query: 1565 KKPKKTSFDQDSDVDIFPSDFPTE-------PPSLPRTGRARKEVKYFAESDEEEDDVDF 1617
K KK +D+ + ++ ++ S + G ++K++K A D E D +F
Sbjct: 466 KDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSKEKKG-SKKDIKKDARKDTESTDAEF 524
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 47.8 bits (112), Expect = 9e-05
Identities = 79/411 (19%), Positives = 161/411 (39%), Gaps = 53/411 (12%)
Query: 1171 LKRKSPSDLWKEDLAAFVEELDKVESQEREDVLAGMSGKAIKGKVGKPKVKKLQLEETMP 1230
L +K ++ E +E++ + S E+ + K + K+ K K LQ E P
Sbjct: 1156 LVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQ--EKKP 1213
Query: 1231 SPYGRRIIPEITAMKADASKKLLKKKKGDLDTAAVKVEFDEEFSGAPVEGAGEEALTPSV 1290
P +++IPE ++++ K LL++KK T K E + AP E + L V
Sbjct: 1214 LPEEKKLIPEEEKIRSEEKKPLLEEKK---PTPEDKKLLPEAKTSAP-EEQKHDLLKSQV 1269
Query: 1291 PINK-------GPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSESDLEE 1343
I + PK +E K+P T++ P SG P + +D+ +++ E+
Sbjct: 1270 QIAEEKLEGRVAPKTVQEGKQPQTKMEGLP--SGTPQSLP-------KEDDKTTKTIKEQ 1320
Query: 1344 TEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDDN----NDLEELKVKASPITN 1399
+P + + + +E+EDD +D L + + I++
Sbjct: 1321 PQPPCTAKPDQVEPGKEK--------TEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISS 1372
Query: 1400 D-GE-DEFVPSD------GLDKDEYTFSPGKSKATP------EKSLHDKKSQDFGNLFSF 1445
GE +P+D GL KD +FS S ++P E ++ L
Sbjct: 1373 SLGEIPSLIPTDEKDILKGLKKD--SFSQESSPSSPSDLAKLESTVLSILEAQASTLADE 1430
Query: 1446 PSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKG---KPSSDTVPKP 1502
S + + + +++ S + + +++ ++ +K K S +P
Sbjct: 1431 KSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSS 1490
Query: 1503 KRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDY 1553
K ++ + V+ + + + + + + + K+R + GS + +Y
Sbjct: 1491 KDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEY 1541
Score = 43.5 bits (101), Expect = 0.002
Identities = 59/265 (22%), Positives = 102/265 (38%), Gaps = 21/265 (7%)
Query: 1274 SGAPVEGAGEEALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDD 1333
S P + + ++ P ++K P+PK+ + K PT G PSAK K+ P +D
Sbjct: 676 SPQPQQTSPKKDAAPKQDLSKAPEPKKPPP-----LVKQPTLHGSPSAKA--KQPPEADS 728
Query: 1334 ESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDDNNDLEELKVK 1393
SK E + +P + A ++PK D + D+ KV+
Sbjct: 729 LSKPAPPKEPS----VPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQ 784
Query: 1394 ASPITNDGEDEFVPSDGLD--KDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSYSQK 1451
+ E++ P D K +F P K +P S + + S P S +
Sbjct: 785 SQ-----AEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSE 839
Query: 1452 SEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKG-KPSS-DTVPKPKRAPKQK 1509
S+ +++ K K K G +P++ TVP P+++PK +
Sbjct: 840 SKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQ 899
Query: 1510 KVVEAVNSDSDSEFGIPK-KTTTPK 1533
+ + + S PK + TTP+
Sbjct: 900 EQSRRFSLNLGSITDAPKSQPTTPQ 924
Score = 39.7 bits (91), Expect = 0.024
Identities = 95/494 (19%), Positives = 177/494 (35%), Gaps = 66/494 (13%)
Query: 1073 EKIQGKITIENRSKKDLIQMLVQRGYESDPVKAWK---EAQEKAAEEDETQNQHDDSSSD 1129
EK K + + Q L GY SD + + + E+D + DS S
Sbjct: 1340 EKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQ 1399
Query: 1130 SGTPSGPDFNYILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWK-----EDL 1184
+PS P L ++ S+ + + L ++ K + +++ + P D K E L
Sbjct: 1400 ESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETL 1459
Query: 1185 AAFVEELDKVESQ-EREDVLAGMSGKAI-KGKVGKPKVKKLQLEETMPSPYG-------- 1234
+ E + ESQ ER+D S + I K K K + + T PY
Sbjct: 1460 EITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSES 1519
Query: 1235 -------RRIIPEITAMKADASKKLLKKKKGD----LDTAAVKVEFDEEFSGAPVEGAGE 1283
R+ + + +D K+ + G+ + +++ DE+ SG+ +
Sbjct: 1520 ENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIR 1579
Query: 1284 EAL---TPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKS--- 1337
L + S K + K + K + R+ S + +R+ W D++ ++
Sbjct: 1580 NQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDE 1639
Query: 1338 -------ESDLEETEPVVIPRDSLLRR---------------AAAERPKYTFDFSEEEDD 1375
E+ +E+E +V+ LRR A + + K + F EE +
Sbjct: 1640 SPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPEL 1699
Query: 1376 DADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKK 1435
+ + D D + +S + P+ DE + S K K +
Sbjct: 1700 EMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKAR 1759
Query: 1436 SQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPS 1495
+ G L P+ SE++ + EE+ ++Q + S +KK K
Sbjct: 1760 HRPHGPL--LPTIEDSSEEEELR---EEEELLKEQEKQREIEQQQRKSS----SKKSKKD 1810
Query: 1496 SDTVPKPKRAPKQK 1509
D + +R + K
Sbjct: 1811 KDELRAQRRRERPK 1824
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 47.8 bits (112), Expect = 9e-05
Identities = 79/411 (19%), Positives = 161/411 (39%), Gaps = 53/411 (12%)
Query: 1171 LKRKSPSDLWKEDLAAFVEELDKVESQEREDVLAGMSGKAIKGKVGKPKVKKLQLEETMP 1230
L +K ++ E +E++ + S E+ + K + K+ K K LQ E P
Sbjct: 1156 LVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQ--EKKP 1213
Query: 1231 SPYGRRIIPEITAMKADASKKLLKKKKGDLDTAAVKVEFDEEFSGAPVEGAGEEALTPSV 1290
P +++IPE ++++ K LL++KK T K E + AP E + L V
Sbjct: 1214 LPEEKKLIPEEEKIRSEEKKPLLEEKK---PTPEDKKLLPEAKTSAP-EEQKHDLLKSQV 1269
Query: 1291 PINK-------GPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKSESDLEE 1343
I + PK +E K+P T++ P SG P + +D+ +++ E+
Sbjct: 1270 QIAEEKLEGRVAPKTVQEGKQPQTKMEGLP--SGTPQSLP-------KEDDKTTKTIKEQ 1320
Query: 1344 TEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDDN----NDLEELKVKASPITN 1399
+P + + + +E+EDD +D L + + I++
Sbjct: 1321 PQPPCTAKPDQVEPGKEK--------TEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISS 1372
Query: 1400 D-GE-DEFVPSD------GLDKDEYTFSPGKSKATP------EKSLHDKKSQDFGNLFSF 1445
GE +P+D GL KD +FS S ++P E ++ L
Sbjct: 1373 SLGEIPSLIPTDEKDILKGLKKD--SFSQESSPSSPSDLAKLESTVLSILEAQASTLADE 1430
Query: 1446 PSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKG---KPSSDTVPKP 1502
S + + + +++ S + + +++ ++ +K K S +P
Sbjct: 1431 KSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSS 1490
Query: 1503 KRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDY 1553
K ++ + V+ + + + + + + + K+R + GS + +Y
Sbjct: 1491 KDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEY 1541
Score = 43.5 bits (101), Expect = 0.002
Identities = 59/265 (22%), Positives = 102/265 (38%), Gaps = 21/265 (7%)
Query: 1274 SGAPVEGAGEEALTPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDD 1333
S P + + ++ P ++K P+PK+ + K PT G PSAK K+ P +D
Sbjct: 676 SPQPQQTSPKKDAAPKQDLSKAPEPKKPPP-----LVKQPTLHGSPSAKA--KQPPEADS 728
Query: 1334 ESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDDNNDLEELKVK 1393
SK E + +P + A ++PK D + D+ KV+
Sbjct: 729 LSKPAPPKEPS----VPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQ 784
Query: 1394 ASPITNDGEDEFVPSDGLD--KDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSYSQK 1451
+ E++ P D K +F P K +P S + + S P S +
Sbjct: 785 SQ-----AEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSE 839
Query: 1452 SEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKG-KPSS-DTVPKPKRAPKQK 1509
S+ +++ K K K G +P++ TVP P+++PK +
Sbjct: 840 SKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQ 899
Query: 1510 KVVEAVNSDSDSEFGIPK-KTTTPK 1533
+ + + S PK + TTP+
Sbjct: 900 EQSRRFSLNLGSITDAPKSQPTTPQ 924
Score = 39.7 bits (91), Expect = 0.024
Identities = 95/494 (19%), Positives = 177/494 (35%), Gaps = 66/494 (13%)
Query: 1073 EKIQGKITIENRSKKDLIQMLVQRGYESDPVKAWK---EAQEKAAEEDETQNQHDDSSSD 1129
EK K + + Q L GY SD + + + E+D + DS S
Sbjct: 1340 EKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQ 1399
Query: 1130 SGTPSGPDFNYILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWK-----EDL 1184
+PS P L ++ S+ + + L ++ K + +++ + P D K E L
Sbjct: 1400 ESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETL 1459
Query: 1185 AAFVEELDKVESQ-EREDVLAGMSGKAI-KGKVGKPKVKKLQLEETMPSPYG-------- 1234
+ E + ESQ ER+D S + I K K K + + T PY
Sbjct: 1460 EITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSES 1519
Query: 1235 -------RRIIPEITAMKADASKKLLKKKKGD----LDTAAVKVEFDEEFSGAPVEGAGE 1283
R+ + + +D K+ + G+ + +++ DE+ SG+ +
Sbjct: 1520 ENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIR 1579
Query: 1284 EAL---TPSVPINKGPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESKS--- 1337
L + S K + K + K + R+ S + +R+ W D++ ++
Sbjct: 1580 NQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDE 1639
Query: 1338 -------ESDLEETEPVVIPRDSLLRR---------------AAAERPKYTFDFSEEEDD 1375
E+ +E+E +V+ LRR A + + K + F EE +
Sbjct: 1640 SPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPEL 1699
Query: 1376 DADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKK 1435
+ + D D + +S + P+ DE + S K K +
Sbjct: 1700 EMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKAR 1759
Query: 1436 SQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPS 1495
+ G L P+ SE++ + EE+ ++Q + S +KK K
Sbjct: 1760 HRPHGPL--LPTIEDSSEEEELR---EEEELLKEQEKQREIEQQQRKSS----SKKSKKD 1810
Query: 1496 SDTVPKPKRAPKQK 1509
D + +R + K
Sbjct: 1811 KDELRAQRRRERPK 1824
>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
sapiens]
Length = 2997
Score = 47.4 bits (111), Expect = 1e-04
Identities = 54/183 (29%), Positives = 74/183 (40%), Gaps = 28/183 (15%)
Query: 1452 SEDDSAKFDSNE----EDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVPKPKRAPK 1507
+ED S F ++ D+ + S Q +K K AKK P PK K+ PK
Sbjct: 608 AEDPSKGFGKDDFPGGVDNQELNRNSLDGSQEEKKKKKRSKAKKD-PKEPKEPKEKKEPK 666
Query: 1508 QKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKP 1567
+ K +A IPK+ K K K + + S N+ P + S K
Sbjct: 667 EPKTPKAPK--------IPKEPKEKKAKTATPKPKSSKKSSNK---KPDSEASALKKKVN 715
Query: 1568 K-KTSFDQDSDVDIFPSDFP----TEPPSLP--RTGRARKEVKY-----FAESDEEEDDV 1615
K KT ++SD+D P P E P + R+ R K +Y F SDEE DD
Sbjct: 716 KGKTEGSENSDLDKTPPPSPPPEEDEDPGVQKRRSSRQVKRKRYTEDLEFKISDEEADDA 775
Query: 1616 DFA 1618
D A
Sbjct: 776 DAA 778
Score = 42.0 bits (97), Expect = 0.005
Identities = 49/159 (30%), Positives = 67/159 (42%), Gaps = 30/159 (18%)
Query: 1240 EITAMKADASKKLLKKKKGDLDTAAVKVEFDEEFSGAPVEGAGEEALTPSVPINKGPK-P 1298
E+ D S++ KKKK K + D + P E +E P P K PK P
Sbjct: 628 ELNRNSLDGSQEEKKKKKRS------KAKKDPKEPKEPKEK--KEPKEPKTP--KAPKIP 677
Query: 1299 KREKKEPGTRVRKTPTSSGKPSAKK-------VKKRNPWSDDESKSESDLEETEPVVIPR 1351
K K++ P SS K S KK +KK+ E SDL++T P P
Sbjct: 678 KEPKEKKAKTATPKPKSSKKSSNKKPDSEASALKKKVNKGKTEGSENSDLDKTPPPSPPP 737
Query: 1352 DS------LLRRAA--AERPKYT----FDFSEEEDDDAD 1378
+ RR++ +R +YT F S+EE DDAD
Sbjct: 738 EEDEDPGVQKRRSSRQVKRKRYTEDLEFKISDEEADDAD 776
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.132 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,797,122
Number of Sequences: 37866
Number of extensions: 3054302
Number of successful extensions: 15442
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 58
Number of HSP's successfully gapped in prelim test: 408
Number of HSP's that attempted gapping in prelim test: 12655
Number of HSP's gapped (non-prelim): 2074
length of query: 1621
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1505
effective length of database: 13,855,062
effective search space: 20851868310
effective search space used: 20851868310
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.