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Search of human proteins with 197927231
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|197927231 hypothetical protein LOC389152 [Homo sapiens]
(262 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|197927231 hypothetical protein LOC389152 [Homo sapiens] 540 e-154
gi|61966747 hypothetical protein LOC389151 [Homo sapiens] 438 e-123
gi|197927236 hypothetical protein LOC729627 [Homo sapiens] 432 e-121
gi|169172682 PREDICTED: hypothetical protein [Homo sapiens] 44 1e-04
gi|169172911 PREDICTED: hypothetical protein [Homo sapiens] 44 1e-04
gi|169172807 PREDICTED: hypothetical protein [Homo sapiens] 44 1e-04
gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 40 0.003
gi|60498978 elastin microfibril interfacer 2 [Homo sapiens] 40 0.003
gi|56549129 transmembrane anchor protein 1 isoform 3 [Homo sapiens] 39 0.005
gi|56549133 transmembrane anchor protein 1 isoform 2 [Homo sapiens] 39 0.005
gi|56549131 transmembrane anchor protein 1 isoform 1 [Homo sapiens] 39 0.005
gi|239757548 PREDICTED: hypothetical protein [Homo sapiens] 38 0.008
gi|153792074 proline rich 12 [Homo sapiens] 38 0.008
gi|56549694 enabled homolog isoform a [Homo sapiens] 37 0.017
gi|39930375 enabled homolog isoform b [Homo sapiens] 37 0.017
gi|24431933 reticulon 4 isoform B [Homo sapiens] 37 0.017
gi|47519490 reticulon 4 isoform D [Homo sapiens] 37 0.017
gi|24431935 reticulon 4 isoform A [Homo sapiens] 37 0.017
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 37 0.017
gi|38683860 insulin receptor substrate 2 [Homo sapiens] 37 0.017
gi|21264337 ArfGAP with RhoGAP domain, ankyrin repeat and PH dom... 37 0.017
gi|236459851 ubinuclein 2 [Homo sapiens] 36 0.030
gi|239753435 PREDICTED: hypothetical protein XP_002345651 [Homo ... 36 0.030
gi|239747993 PREDICTED: hypothetical protein XP_002346504 [Homo ... 36 0.030
gi|239741891 PREDICTED: hypothetical protein XP_002342316 [Homo ... 36 0.030
gi|23065526 growth arrest-specific 2 like 1 isoform a [Homo sapi... 36 0.030
gi|19923777 growth arrest-specific 2 like 1 isoform a [Homo sapi... 36 0.030
gi|223633988 hypothetical protein LOC85379 [Homo sapiens] 35 0.051
gi|239747180 PREDICTED: hypothetical protein XP_002343933 [Homo ... 35 0.051
gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 35 0.051
>gi|197927231 hypothetical protein LOC389152 [Homo sapiens]
Length = 262
Score = 540 bits (1390), Expect = e-154
Identities = 262/262 (100%), Positives = 262/262 (100%)
Query: 1 MGSRPCSPSACLAPWWGQQPGGPGPAKRSRLEEPAGPESRAAPSPEDPAGTPAVDALTSM 60
MGSRPCSPSACLAPWWGQQPGGPGPAKRSRLEEPAGPESRAAPSPEDPAGTPAVDALTSM
Sbjct: 1 MGSRPCSPSACLAPWWGQQPGGPGPAKRSRLEEPAGPESRAAPSPEDPAGTPAVDALTSM 60
Query: 61 VVLDAGCALRVPLEDVDLVLELAPMSVLRVSLGGHTLIVIPEVLLSSVDECSGAQGDWSA 120
VVLDAGCALRVPLEDVDLVLELAPMSVLRVSLGGHTLIVIPEVLLSSVDECSGAQGDWSA
Sbjct: 61 VVLDAGCALRVPLEDVDLVLELAPMSVLRVSLGGHTLIVIPEVLLSSVDECSGAQGDWSA 120
Query: 121 GLEVDVFLGAHGEDVVVEQEVCASVPEIAAEEEAYEEDADSEFPELWMDSAAGSAAGLYP 180
GLEVDVFLGAHGEDVVVEQEVCASVPEIAAEEEAYEEDADSEFPELWMDSAAGSAAGLYP
Sbjct: 121 GLEVDVFLGAHGEDVVVEQEVCASVPEIAAEEEAYEEDADSEFPELWMDSAAGSAAGLYP 180
Query: 181 SARSMFSPYREGPIRGPCALAPNPSSERRSPRPIFDLEFHLLEPVPSSPLQPLPPSPSPG 240
SARSMFSPYREGPIRGPCALAPNPSSERRSPRPIFDLEFHLLEPVPSSPLQPLPPSPSPG
Sbjct: 181 SARSMFSPYREGPIRGPCALAPNPSSERRSPRPIFDLEFHLLEPVPSSPLQPLPPSPSPG 240
Query: 241 PHARPELPERPPCKVRRRLFQE 262
PHARPELPERPPCKVRRRLFQE
Sbjct: 241 PHARPELPERPPCKVRRRLFQE 262
>gi|61966747 hypothetical protein LOC389151 [Homo sapiens]
Length = 265
Score = 438 bits (1127), Expect = e-123
Identities = 226/264 (85%), Positives = 232/264 (87%), Gaps = 3/264 (1%)
Query: 1 MGSRPCSPSACLAPWWGQQPGGPGPAKRSRLEEPAGPESRAAPSPEDPAGTPAVDALTSM 60
M SRP SPSA APWWGQQPGGPGPAKR RLEEPAGPE RAAPS EDPAG PAVDALTS+
Sbjct: 1 MVSRPRSPSAFPAPWWGQQPGGPGPAKRLRLEEPAGPEPRAAPSLEDPAGDPAVDALTSI 60
Query: 61 VVLDAGCALRVPLEDVDLVLELAPMSVLRVSLGGHTLIVIPEVLLSSVDECSGAQGDWSA 120
VVL AGCALRVPL+DVDLVLE AP S+LRVSLGGHTLI+IPEVLLSSVDE SGAQ D SA
Sbjct: 61 VVLAAGCALRVPLDDVDLVLEPAPTSILRVSLGGHTLILIPEVLLSSVDERSGAQHDSSA 120
Query: 121 GLEVDVFLGAHGEDVVVEQEVCASVPEIAAEEEAYEEDADSEFPELWMDSAAGSAAGLYP 180
GLEVDVFLGA EDVVVE E CASVPEIAA+EEAYEEDAD EFPEL MDS GSAAGLYP
Sbjct: 121 GLEVDVFLGAVREDVVVELEFCASVPEIAAQEEAYEEDADPEFPELRMDSPTGSAAGLYP 180
Query: 181 SARSMFSPYREGPIRGPCALAPNPSSERRSPRPIFDLEFHLLEPVPSSPLQPLPPSP--- 237
S+RSMF PYREGPI PCALAPNPSSERRSPRPIFDLEF LLEPVPSSPLQPLPPSP
Sbjct: 181 SSRSMFIPYREGPIPEPCALAPNPSSERRSPRPIFDLEFRLLEPVPSSPLQPLPPSPCVG 240
Query: 238 SPGPHARPELPERPPCKVRRRLFQ 261
SPGPHAR LPERPPCK RRRLFQ
Sbjct: 241 SPGPHARSPLPERPPCKARRRLFQ 264
>gi|197927236 hypothetical protein LOC729627 [Homo sapiens]
Length = 266
Score = 432 bits (1112), Expect = e-121
Identities = 225/266 (84%), Positives = 231/266 (86%), Gaps = 4/266 (1%)
Query: 1 MGSRPCSPSACLAPWWGQQPGGPGPAKRSRLEEPAGPESRAAPSPEDPAGTPAVDALTSM 60
MGSRP SPSA APWWGQQPGGPGPAKR RLEEPAGPE R APS EDPAGTPAV ALTS+
Sbjct: 1 MGSRPRSPSAFPAPWWGQQPGGPGPAKRLRLEEPAGPEPRVAPSLEDPAGTPAVGALTSI 60
Query: 61 VVLDAGCALRVPLEDVDLVLELAPMSVLRVSLGGHTLIVIPEVLLSSVDECSGAQGDWSA 120
VVL AGCALRVPL+DVDLVLEL P S+LRVSL GHTLI+IPEVLLSSVDE SGAQ D SA
Sbjct: 61 VVLAAGCALRVPLDDVDLVLELPPTSILRVSLDGHTLILIPEVLLSSVDERSGAQDDSSA 120
Query: 121 GLEVDVFLGAHGEDVVVEQEV-CASVPEIAAEEEAYEEDADSEFPELWMDSAAGSAAGLY 179
GLEVDVFLGA EDVVVEQEV CASVPEIAA+EEAYEEDAD EFPEL MDSAAGSAAGLY
Sbjct: 121 GLEVDVFLGALREDVVVEQEVFCASVPEIAAQEEAYEEDADPEFPELQMDSAAGSAAGLY 180
Query: 180 PSARSMFSPYREGPIRGPCALAPNPSSERRSPRPIFDLEFHLLEPVPSSPLQPLPPSP-- 237
SARSMFSPYREGPI PCALAPNPSSE SP P FD EF LLEPVPSSPLQPLPPSP
Sbjct: 181 SSARSMFSPYREGPIPEPCALAPNPSSEGHSPGPFFDPEFRLLEPVPSSPLQPLPPSPRV 240
Query: 238 -SPGPHARPELPERPPCKVRRRLFQE 262
SPGPHA P LP+RPPCK RRRLFQE
Sbjct: 241 GSPGPHAHPPLPKRPPCKARRRLFQE 266
>gi|169172682 PREDICTED: hypothetical protein [Homo sapiens]
Length = 237
Score = 43.9 bits (102), Expect = 1e-04
Identities = 43/145 (29%), Positives = 68/145 (46%), Gaps = 12/145 (8%)
Query: 38 ESRAAPSPEDPAGTPAVDALTSMVVLDAGCALRVPLEDVDLVLELAPMSVLRVSLGGHTL 97
+S P + +GT + M+VL+ G +R+ LE+V L+L AP +VL+++L L
Sbjct: 63 QSLELPQNQQDSGTEEL-----MIVLEQGTEVRLSLEEVILIL--APETVLQLTLENTVL 115
Query: 98 IVIPEVLLSSVDEC-SGAQGDWSAGLEVDVFLGAHGEDVVVEQEVCASVPEIAAEEEAYE 156
+++PE +L S D S Q + D L H +D + +VP AE E
Sbjct: 116 VIVPEHVLRSEDGLQSPVQIQYIIPSVDDFSLEFHAQDGDISDMRRENVPFSPAE----E 171
Query: 157 EDADSEFPELWMDSAAGSAAGLYPS 181
A + + M A AG+ PS
Sbjct: 172 GKAAPLYQQPLMIPQANHMAGISPS 196
>gi|169172911 PREDICTED: hypothetical protein [Homo sapiens]
Length = 237
Score = 43.9 bits (102), Expect = 1e-04
Identities = 43/145 (29%), Positives = 68/145 (46%), Gaps = 12/145 (8%)
Query: 38 ESRAAPSPEDPAGTPAVDALTSMVVLDAGCALRVPLEDVDLVLELAPMSVLRVSLGGHTL 97
+S P + +GT + M+VL+ G +R+ LE+V L+L AP +VL+++L L
Sbjct: 63 QSLELPQNQQDSGTEEL-----MIVLEQGTEVRLSLEEVILIL--APETVLQLTLENTVL 115
Query: 98 IVIPEVLLSSVDEC-SGAQGDWSAGLEVDVFLGAHGEDVVVEQEVCASVPEIAAEEEAYE 156
+++PE +L S D S Q + D L H +D + +VP AE E
Sbjct: 116 VIVPEHVLRSEDGLQSPVQIQYIIPSVDDFSLEFHAQDGDISDMRRENVPFSPAE----E 171
Query: 157 EDADSEFPELWMDSAAGSAAGLYPS 181
A + + M A AG+ PS
Sbjct: 172 GKAAPLYQQPLMIPQANHMAGISPS 196
>gi|169172807 PREDICTED: hypothetical protein [Homo sapiens]
Length = 277
Score = 43.9 bits (102), Expect = 1e-04
Identities = 43/145 (29%), Positives = 68/145 (46%), Gaps = 12/145 (8%)
Query: 38 ESRAAPSPEDPAGTPAVDALTSMVVLDAGCALRVPLEDVDLVLELAPMSVLRVSLGGHTL 97
+S P + +GT + M+VL+ G +R+ LE+V L+L AP +VL+++L L
Sbjct: 63 QSLELPQNQQDSGTEEL-----MIVLEQGTEVRLSLEEVILIL--APETVLQLTLENTVL 115
Query: 98 IVIPEVLLSSVDEC-SGAQGDWSAGLEVDVFLGAHGEDVVVEQEVCASVPEIAAEEEAYE 156
+++PE +L S D S Q + D L H +D + +VP AE E
Sbjct: 116 VIVPEHVLRSEDGLQSPVQIQYIIPSVDDFSLEFHAQDGDISDMRRENVPFSPAE----E 171
Query: 157 EDADSEFPELWMDSAAGSAAGLYPS 181
A + + M A AG+ PS
Sbjct: 172 GKAAPLYQQPLMIPQANHMAGISPS 196
>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
Length = 1526
Score = 39.7 bits (91), Expect = 0.003
Identities = 42/163 (25%), Positives = 67/163 (41%), Gaps = 34/163 (20%)
Query: 117 DWSAGLEVDVFL--------GAHGEDVVVEQEVCASVPEIAAEEEAYEEDADSEFPELWM 168
DW LE ++ L + ++ E A+ ++ + + Y + + P+ +
Sbjct: 967 DWIKNLEEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQ-HL 1025
Query: 169 DSAAGSAAGLYPSARSMFSPYR-----EGPI--------RGPCALAPNPSSERRSPRPIF 215
++ S G PS+ SP + EGP+ R P + P P S + SP
Sbjct: 1026 QPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAP-SRTPGPPSAQSSP---- 1080
Query: 216 DLEFHLLEPVPSS-PLQPL----PPSPSP-GPHARPELPERPP 252
++ P+P P QPL PP P P P RP P+RPP
Sbjct: 1081 -IDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPP 1122
Score = 28.5 bits (62), Expect = 6.2
Identities = 27/89 (30%), Positives = 36/89 (40%), Gaps = 12/89 (13%)
Query: 171 AAGSAAGLYPSARSMFSPYREGPIRGPCALAPNPSSERRS--PRPIFDLEFHLLEPVPSS 228
A SA L P ++S S +G P L P + +S P P L+
Sbjct: 1165 ARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQ---------E 1215
Query: 229 PLQPLP-PSPSPGPHARPELPERPPCKVR 256
PL P+ P P GP E P +PP + R
Sbjct: 1216 PLVPVAAPMPQSGPQPNLETPPQPPPRSR 1244
>gi|60498978 elastin microfibril interfacer 2 [Homo sapiens]
Length = 1053
Score = 39.7 bits (91), Expect = 0.003
Identities = 29/123 (23%), Positives = 53/123 (43%), Gaps = 10/123 (8%)
Query: 139 QEVCASVPEIAAEEEAYEEDADSEFPELW---------MDSAAGSAAGLYPSARSMFSPY 189
++ C+ + I+ + +E + LW + S + +GL S + +S
Sbjct: 710 EKTCSKLDSISGNLQRIKEGLNKHVSSLWNCVRQMNGTLRSHSRDISGLKNSVQQFYSHV 769
Query: 190 REGPIRGPCALAPNPSSERRSPRPIFDLEFHLLEPVPSSPLQPLPPSPSPGPHARPELPE 249
+ + PS++ SP P + L+P P+ P +P P+ + P RP LP+
Sbjct: 770 FQISTDLQDLVKFQPSAKAPSPPPPAEAPKEPLQPEPAPP-RPSGPATAEDPGRRPVLPQ 828
Query: 250 RPP 252
RPP
Sbjct: 829 RPP 831
>gi|56549129 transmembrane anchor protein 1 isoform 3 [Homo sapiens]
Length = 170
Score = 38.9 bits (89), Expect = 0.005
Identities = 22/51 (43%), Positives = 26/51 (50%), Gaps = 4/51 (7%)
Query: 3 SRPCSPSACLAPWWGQQPGGPGPAKRSRLEEPAGPESRAAPSPEDPAGTPA 53
SRPC+P +P ++PG PA L EPAGP P DPA PA
Sbjct: 57 SRPCAPEPAASPAGPEEPG--EPAGLGELGEPAGPGEPEGPG--DPAAAPA 103
>gi|56549133 transmembrane anchor protein 1 isoform 2 [Homo sapiens]
Length = 177
Score = 38.9 bits (89), Expect = 0.005
Identities = 22/51 (43%), Positives = 26/51 (50%), Gaps = 4/51 (7%)
Query: 3 SRPCSPSACLAPWWGQQPGGPGPAKRSRLEEPAGPESRAAPSPEDPAGTPA 53
SRPC+P +P ++PG PA L EPAGP P DPA PA
Sbjct: 57 SRPCAPEPAASPAGPEEPG--EPAGLGELGEPAGPGEPEGPG--DPAAAPA 103
>gi|56549131 transmembrane anchor protein 1 isoform 1 [Homo sapiens]
Length = 204
Score = 38.9 bits (89), Expect = 0.005
Identities = 22/51 (43%), Positives = 26/51 (50%), Gaps = 4/51 (7%)
Query: 3 SRPCSPSACLAPWWGQQPGGPGPAKRSRLEEPAGPESRAAPSPEDPAGTPA 53
SRPC+P +P ++PG PA L EPAGP P DPA PA
Sbjct: 57 SRPCAPEPAASPAGPEEPG--EPAGLGELGEPAGPGEPEGPG--DPAAAPA 103
>gi|239757548 PREDICTED: hypothetical protein [Homo sapiens]
Length = 132
Score = 38.1 bits (87), Expect = 0.008
Identities = 34/89 (38%), Positives = 42/89 (47%), Gaps = 13/89 (14%)
Query: 170 SAAGSAAGLYPSARSMFSPYR----EGPIRGPCALAPNPSSERRSPRPIFDLEFHLLEPV 225
S GSAAG + +++ P+R E R P PNPS R SP F+L E
Sbjct: 37 SCLGSAAGSQQT-ETLWWPWRPWWAENKSRRPLPSMPNPSICRESP-----TVFNLREEA 90
Query: 226 PS-SPLQPLPPSPSPGPHARPELPERPPC 253
P+ S LQ P+ P P R LP PPC
Sbjct: 91 PTQSDLQRGSPAKLPAPPLR--LPALPPC 117
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 38.1 bits (87), Expect = 0.008
Identities = 21/51 (41%), Positives = 23/51 (45%), Gaps = 2/51 (3%)
Query: 202 PNPSSERRSPRPIFDLEFHLLEPVPSSPLQPLPPSPSPGPHARPELPERPP 252
P P P+P L+ P PSSP P PP P P P A P P PP
Sbjct: 1469 PQPPPPPPPPQPALPSPPPLVAPTPSSP--PPPPLPPPPPPAMPSPPPPPP 1517
Score = 33.1 bits (74), Expect = 0.25
Identities = 33/110 (30%), Positives = 44/110 (40%), Gaps = 19/110 (17%)
Query: 156 EEDADSEFPELWMD-SAAGSAAGLYPSARSMFSPYREGPIRGPCALAPNP--------SS 206
EED+ ++ +L S+A SA P A + +GP P A P P ++
Sbjct: 1384 EEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSAN 1443
Query: 207 ERRSPRPIFDLEFHLLE----PVPSSPLQPLPPSPSPGPHARPELPERPP 252
+P P LLE P P P P P P P +P LP PP
Sbjct: 1444 SNGTPEP------PLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPP 1487
Score = 32.7 bits (73), Expect = 0.33
Identities = 21/55 (38%), Positives = 24/55 (43%), Gaps = 10/55 (18%)
Query: 197 PCALAPNPSSERRSPRPIFDLEFHLLEPVPSSPLQPLPPSPSPGPHARPELPERP 251
P +AP PSS P P P P+ P P PP P+ P A P PE P
Sbjct: 1486 PPLVAPTPSSPPPPPLPP--------PPPPAMPSPPPPPPPAAAPLAAP--PEEP 1530
Score = 30.4 bits (67), Expect = 1.6
Identities = 24/89 (26%), Positives = 35/89 (39%), Gaps = 6/89 (6%)
Query: 164 PELWMDSAAGSAAGLYPSARSMFSPYREGPIRGPCALAP----NPSSERRSPRPIFDLEF 219
PE D AG+ P A + PY G G P +P+ P +
Sbjct: 968 PEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPL 1027
Query: 220 HLLEPVP--SSPLQPLPPSPSPGPHARPE 246
L++ P ++P P PP P P P + P+
Sbjct: 1028 GLIQSGPHQAAPPPPPPPPPPPAPASEPK 1056
Score = 28.9 bits (63), Expect = 4.8
Identities = 14/29 (48%), Positives = 15/29 (51%)
Query: 20 PGGPGPAKRSRLEEPAGPESRAAPSPEDP 48
P P P + A PE AAPSPEDP
Sbjct: 1510 PSPPPPPPPAAAPLAAPPEEPAAPSPEDP 1538
Score = 28.5 bits (62), Expect = 6.2
Identities = 18/50 (36%), Positives = 20/50 (40%), Gaps = 1/50 (2%)
Query: 197 PCALAPNPSSERRSPRPIFD-LEFHLLEPVPSSPLQPLPPSPSPGPHARP 245
P L P+ S SP P + HLLEP PP P P P P
Sbjct: 798 PPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMP 847
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 37.0 bits (84), Expect = 0.017
Identities = 28/83 (33%), Positives = 38/83 (45%), Gaps = 8/83 (9%)
Query: 169 DSAAGSAAGLYPSARSMFSPYREGPIRGPCALAPNPSSERRSPRPIFDLEFHLLEPVPSS 228
DS+A S GL +++ +P ++G + GP A P P P P + + P P
Sbjct: 283 DSSA-SEPGLQAASQPAETPSQQGIVLGPLAPPPPP------PLPPGPAQASVALPPPPG 335
Query: 229 PLQPLPPSPSPGPHARPELPERP 251
P P PP PS GP P P P
Sbjct: 336 P-PPPPPLPSTGPPPPPPPPPLP 357
Score = 28.9 bits (63), Expect = 4.8
Identities = 21/61 (34%), Positives = 22/61 (36%), Gaps = 10/61 (16%)
Query: 188 PYREGPIRGPCALAPNPSSERRSPRPIFDLEFHLLEPVPSSPLQPLP---PSPSPGPHAR 244
P GP + AL P P P P P P P PLP P P P P A
Sbjct: 318 PLPPGPAQASVALPPPPGPPPPPPLPSTG-------PPPPPPPPPLPNQVPPPPPPPPAP 370
Query: 245 P 245
P
Sbjct: 371 P 371
Score = 28.1 bits (61), Expect = 8.1
Identities = 13/32 (40%), Positives = 16/32 (50%)
Query: 221 LLEPVPSSPLQPLPPSPSPGPHARPELPERPP 252
+L P+ P PLPP P+ A P P PP
Sbjct: 307 VLGPLAPPPPPPLPPGPAQASVALPPPPGPPP 338
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 37.0 bits (84), Expect = 0.017
Identities = 28/83 (33%), Positives = 38/83 (45%), Gaps = 8/83 (9%)
Query: 169 DSAAGSAAGLYPSARSMFSPYREGPIRGPCALAPNPSSERRSPRPIFDLEFHLLEPVPSS 228
DS+A S GL +++ +P ++G + GP A P P P P + + P P
Sbjct: 283 DSSA-SEPGLQAASQPAETPSQQGIVLGPLAPPPPP------PLPPGPAQASVALPPPPG 335
Query: 229 PLQPLPPSPSPGPHARPELPERP 251
P P PP PS GP P P P
Sbjct: 336 P-PPPPPLPSTGPPPPPPPPPLP 357
Score = 28.9 bits (63), Expect = 4.8
Identities = 21/61 (34%), Positives = 22/61 (36%), Gaps = 10/61 (16%)
Query: 188 PYREGPIRGPCALAPNPSSERRSPRPIFDLEFHLLEPVPSSPLQPLP---PSPSPGPHAR 244
P GP + AL P P P P P P P PLP P P P P A
Sbjct: 318 PLPPGPAQASVALPPPPGPPPPPPLPSTG-------PPPPPPPPPLPNQVPPPPPPPPAP 370
Query: 245 P 245
P
Sbjct: 371 P 371
Score = 28.1 bits (61), Expect = 8.1
Identities = 13/32 (40%), Positives = 16/32 (50%)
Query: 221 LLEPVPSSPLQPLPPSPSPGPHARPELPERPP 252
+L P+ P PLPP P+ A P P PP
Sbjct: 307 VLGPLAPPPPPPLPPGPAQASVALPPPPGPPP 338
>gi|24431933 reticulon 4 isoform B [Homo sapiens]
Length = 373
Score = 37.0 bits (84), Expect = 0.017
Identities = 39/115 (33%), Positives = 49/115 (42%), Gaps = 20/115 (17%)
Query: 151 EEEAYEEDADSEFPELWM---DSAAGSAAGLYPSARSMFSPYRE-------GPIRGPCAL 200
EEE EED D + EL + AAG +A P+A + +P + RGP
Sbjct: 37 EEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPA 96
Query: 201 APNPSSERR---SPRPIFDLEFHLLEPVPSSPLQPLPPSPSPGPHARPELPERPP 252
AP + ER+ P P+ P P SPL SPS P E P RPP
Sbjct: 97 APPVAPERQPSWDPSPVSS-----TVPAP-SPLSAAAVSPSKLPE-DDEPPARPP 144
>gi|47519490 reticulon 4 isoform D [Homo sapiens]
Length = 392
Score = 37.0 bits (84), Expect = 0.017
Identities = 39/115 (33%), Positives = 49/115 (42%), Gaps = 20/115 (17%)
Query: 151 EEEAYEEDADSEFPELWM---DSAAGSAAGLYPSARSMFSPYRE-------GPIRGPCAL 200
EEE EED D + EL + AAG +A P+A + +P + RGP
Sbjct: 37 EEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPA 96
Query: 201 APNPSSERR---SPRPIFDLEFHLLEPVPSSPLQPLPPSPSPGPHARPELPERPP 252
AP + ER+ P P+ P P SPL SPS P E P RPP
Sbjct: 97 APPVAPERQPSWDPSPVSS-----TVPAP-SPLSAAAVSPSKLPE-DDEPPARPP 144
>gi|24431935 reticulon 4 isoform A [Homo sapiens]
Length = 1192
Score = 37.0 bits (84), Expect = 0.017
Identities = 39/115 (33%), Positives = 49/115 (42%), Gaps = 20/115 (17%)
Query: 151 EEEAYEEDADSEFPELWM---DSAAGSAAGLYPSARSMFSPYRE-------GPIRGPCAL 200
EEE EED D + EL + AAG +A P+A + +P + RGP
Sbjct: 37 EEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPA 96
Query: 201 APNPSSERR---SPRPIFDLEFHLLEPVPSSPLQPLPPSPSPGPHARPELPERPP 252
AP + ER+ P P+ P P SPL SPS P E P RPP
Sbjct: 97 APPVAPERQPSWDPSPVSS-----TVPAP-SPLSAAAVSPSKLPE-DDEPPARPP 144
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 37.0 bits (84), Expect = 0.017
Identities = 31/95 (32%), Positives = 38/95 (40%), Gaps = 17/95 (17%)
Query: 180 PSARSMFSPYREGPIRGP---CALAPNPSSERRSPRPIFDLEFHLLEPVPSSP------L 230
P A +F P+ E P+ P L+P P + R SP P E P SP L
Sbjct: 594 PEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRL 653
Query: 231 QPLP------PSPSPGPHARP--ELPERPPCKVRR 257
PLP P P P + P E P PP + R
Sbjct: 654 SPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASR 688
Score = 35.4 bits (80), Expect = 0.051
Identities = 66/256 (25%), Positives = 90/256 (35%), Gaps = 56/256 (21%)
Query: 12 LAPWWGQQPGGPGPAKRSRLEEPAGPESRAAPSPED-PAGTPAVDALTSMVVLDAGCALR 70
L+P + P P P + SRL P +S +P PED PA P D+L S+
Sbjct: 671 LSPPPEESPTSP-PPEASRLSPPP-EDSPTSPPPEDSPASPPPEDSLMSL---------- 718
Query: 71 VPLEDVDLVLELAPMSVLRVSLGGHTLIVIPEVLLSSVDECSGAQGDWSAGLEVDVFLGA 130
PLE+ L+ +PE C ++G + + L
Sbjct: 719 -PLEE-------------------SPLLPLPE----EPQLCPRSEGPHLSPRPEEPHLSP 754
Query: 131 HGEDVVVEQEVCASVPEIAAEEEAYEEDADSEFPELWMDSAAGSAAGLYPSARSM-FSPY 189
E+ + + A P ++ + E A E P L S L P + SP
Sbjct: 755 RPEEPHLSPQ--AEEPHLSPQPEEPCLCAVPEEPHL---SPQAEGPHLSPQPEELHLSPQ 809
Query: 190 REGPIRGPC----ALAPNPSSERRSPR---PIFDL---EFHLLEPVPSSPLQPLPPSPSP 239
E P P L+P P SP+ P E HL + PL P P P
Sbjct: 810 TEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPE 869
Query: 240 GPHARP---ELPERPP 252
P P ELP PP
Sbjct: 870 EPGQCPAPEELPLFPP 885
Score = 35.0 bits (79), Expect = 0.066
Identities = 27/78 (34%), Positives = 32/78 (41%), Gaps = 12/78 (15%)
Query: 180 PSARSMFSPYREGPIRGPCALAPNPSSERRSPRPIFDLEFHLLEPVPSSPLQPLPPSPSP 239
P S FSP E P+ P P+P+ LE L P +SPL P P SP
Sbjct: 506 PPESSPFSPLEESPLSPPEESPPSPA-----------LETPLSPPPEASPLSP-PFEESP 553
Query: 240 GPHARPELPERPPCKVRR 257
ELP PP + R
Sbjct: 554 LSPPPEELPTSPPPEASR 571
Score = 33.5 bits (75), Expect = 0.19
Identities = 38/120 (31%), Positives = 47/120 (39%), Gaps = 15/120 (12%)
Query: 146 PEIAAEEEAYEEDADSEFPELWMDSAAGSAAGLYPSARSMFSPYREGPIRGPCALAPNPS 205
PE + +EE S PE S A+ L P SP P P ++P P
Sbjct: 540 PEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEE--SPMSPPPEESP--MSPPPE 595
Query: 206 SERRSPRPIFDLEFHLLEPVPSSPLQPLP------PSPSPGPHARP--ELPERPPCKVRR 257
+ R P F+ E L P SPL P P P P P + P E P PP +V R
Sbjct: 596 ASRLFPP--FE-ESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSR 652
Score = 32.0 bits (71), Expect = 0.56
Identities = 24/78 (30%), Positives = 31/78 (39%), Gaps = 21/78 (26%)
Query: 183 RSMFSPYREGPIRGPCALAPNPSSERRSPRPIFDLEFHLLEPVPSSPLQPLPPSPSPGP- 241
R + +P E P P LAP+P+S EP+ P +PL P P P
Sbjct: 4904 RQLSAPPPEEPSPPPSPLAPSPASPPT-------------EPLVELPTEPLAEPPVPSPL 4950
Query: 242 -------HARPELPERPP 252
ARP+ RPP
Sbjct: 4951 PLASSPESARPKPRARPP 4968
Score = 28.9 bits (63), Expect = 4.8
Identities = 25/71 (35%), Positives = 30/71 (42%), Gaps = 10/71 (14%)
Query: 192 GPIRGPC---ALAPNPSSERRSPRPIFDLEFH-LLEPV-----PSSPLQPLPPSPSPGPH 242
GP GP P P R P P L +L PV PSSP +P PS P P
Sbjct: 4268 GPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPS 4327
Query: 243 AR-PELPERPP 252
++ P + PP
Sbjct: 4328 SQLPTEAQLPP 4338
Score = 28.1 bits (61), Expect = 8.1
Identities = 25/80 (31%), Positives = 29/80 (36%), Gaps = 1/80 (1%)
Query: 178 LYPSARSMFSPYREGPIRGPCALAPNPSSERRSPRPIFDLEFHLLEPVPSSPLQPLPPSP 237
L P S SP E P+ P +P SP E P +S L P PP
Sbjct: 520 LSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSP-PPEE 578
Query: 238 SPGPHARPELPERPPCKVRR 257
SP E P PP + R
Sbjct: 579 SPMSPPPEESPMSPPPEASR 598
>gi|38683860 insulin receptor substrate 2 [Homo sapiens]
Length = 1338
Score = 37.0 bits (84), Expect = 0.017
Identities = 26/70 (37%), Positives = 32/70 (45%), Gaps = 5/70 (7%)
Query: 183 RSMFSPYREGPIRGPCALAPNPSSERRSPRPIFDLEFHLLEPVPSSPLQPLPPSPSPGPH 242
RS S Y P +P P + S P+ L+ LL P SSP PLPP PS P
Sbjct: 972 RSPLSDYMNLDFSSP--KSPKPGAP--SGHPVGSLD-GLLSPEASSPYPPLPPRPSASPS 1026
Query: 243 ARPELPERPP 252
+ + P PP
Sbjct: 1027 SSLQPPPPPP 1036
Score = 28.9 bits (63), Expect = 4.8
Identities = 15/27 (55%), Positives = 16/27 (59%), Gaps = 5/27 (18%)
Query: 226 PSSPLQPLPPSPSPGPHARPELPERPP 252
PSS LQP PP P+PG EL PP
Sbjct: 1025 PSSSLQPPPPPPAPG-----ELYRLPP 1046
>gi|21264337 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
[Homo sapiens]
Length = 1544
Score = 37.0 bits (84), Expect = 0.017
Identities = 38/136 (27%), Positives = 50/136 (36%), Gaps = 34/136 (25%)
Query: 151 EEEAYEEDADSE---FPELWMDSAAGSAA---------GLYPSARSMFSPYRE-----GP 193
EE YEE E FPEL D++ + S +S+ P+ G
Sbjct: 1399 EEPVYEEPVYEEVGAFPELIQDTSTSFSTTREWTVKPENPLTSQKSLDQPFLSKSSTLGQ 1458
Query: 194 IRGPCALAPNPSSERRSPRPIFDLEFHLLEPV----------------PSSPLQPLPPSP 237
P P P S + SP+ LE LL+ + PS P P PSP
Sbjct: 1459 EERPPEPPPGPPS-KSSPQARGSLEEQLLQELSSLILRKGETTAGLGSPSQPSSPQSPSP 1517
Query: 238 SPGPHARPELPERPPC 253
+ P P P +PPC
Sbjct: 1518 TGLPTQTPGFPTQPPC 1533
>gi|236459851 ubinuclein 2 [Homo sapiens]
Length = 1347
Score = 36.2 bits (82), Expect = 0.030
Identities = 35/105 (33%), Positives = 41/105 (39%), Gaps = 23/105 (21%)
Query: 151 EEEAYEEDADSEFPELWMDSAAGSAAGLYPSARSMFSP-YREGPI--RGPCALAPNPSSE 207
E + Y E A +E P A P+ RS P RE P+ R P S +
Sbjct: 39 EPQPYREPARAEPP-----------APREPAPRSDAQPPSREKPLPQREVSRAEPPMSLQ 87
Query: 208 RRSPRPIFDLEFHLLEPVPSSPLQPLPPSPSPGPHARPELPERPP 252
R PRP EP P P PL P P +R E P RPP
Sbjct: 88 REPPRP---------EPPPPFPPLPLQPPPPRESASRAEQPPRPP 123
>gi|239753435 PREDICTED: hypothetical protein XP_002345651 [Homo
sapiens]
Length = 218
Score = 36.2 bits (82), Expect = 0.030
Identities = 23/58 (39%), Positives = 24/58 (41%), Gaps = 9/58 (15%)
Query: 197 PCAL--APNPSSERRSPRPIFDLEFHLLEPVPSSPLQPLPPSPSPGPHARPELPERPP 252
PC L P P R+ PRP P P P P PP P P P P P RPP
Sbjct: 18 PCGLWSPPPPLPPRKPPRPP-------KPPRPLPPNPPRPPLPPPRPPKPPLPPPRPP 68
>gi|239747993 PREDICTED: hypothetical protein XP_002346504 [Homo
sapiens]
Length = 218
Score = 36.2 bits (82), Expect = 0.030
Identities = 23/58 (39%), Positives = 24/58 (41%), Gaps = 9/58 (15%)
Query: 197 PCAL--APNPSSERRSPRPIFDLEFHLLEPVPSSPLQPLPPSPSPGPHARPELPERPP 252
PC L P P R+ PRP P P P P PP P P P P P RPP
Sbjct: 18 PCGLWSPPPPLPPRKPPRPP-------KPPRPLPPNPPRPPLPPPRPPKPPLPPPRPP 68
>gi|239741891 PREDICTED: hypothetical protein XP_002342316 [Homo
sapiens]
Length = 218
Score = 36.2 bits (82), Expect = 0.030
Identities = 23/58 (39%), Positives = 24/58 (41%), Gaps = 9/58 (15%)
Query: 197 PCAL--APNPSSERRSPRPIFDLEFHLLEPVPSSPLQPLPPSPSPGPHARPELPERPP 252
PC L P P R+ PRP P P P P PP P P P P P RPP
Sbjct: 18 PCGLWSPPPPLPPRKPPRPP-------KPPRPLPPNPPRPPLPPPRPPKPPLPPPRPP 68
>gi|23065526 growth arrest-specific 2 like 1 isoform a [Homo
sapiens]
Length = 681
Score = 36.2 bits (82), Expect = 0.030
Identities = 24/66 (36%), Positives = 27/66 (40%), Gaps = 10/66 (15%)
Query: 186 FSPYREGPIRGPCALAPNPSSERRSPRPIFDLEFHLLEPVPSSPLQPLPPSPSPGPHARP 245
FSP R P P +P P SERR RP E P S L+ P P R
Sbjct: 291 FSPQRVSPTTSPRPASPVPGSERRGSRP---------EMTPVS-LRSTKEGPETPPRPRD 340
Query: 246 ELPERP 251
+LP P
Sbjct: 341 QLPPHP 346
>gi|19923777 growth arrest-specific 2 like 1 isoform a [Homo
sapiens]
Length = 681
Score = 36.2 bits (82), Expect = 0.030
Identities = 24/66 (36%), Positives = 27/66 (40%), Gaps = 10/66 (15%)
Query: 186 FSPYREGPIRGPCALAPNPSSERRSPRPIFDLEFHLLEPVPSSPLQPLPPSPSPGPHARP 245
FSP R P P +P P SERR RP E P S L+ P P R
Sbjct: 291 FSPQRVSPTTSPRPASPVPGSERRGSRP---------EMTPVS-LRSTKEGPETPPRPRD 340
Query: 246 ELPERP 251
+LP P
Sbjct: 341 QLPPHP 346
>gi|223633988 hypothetical protein LOC85379 [Homo sapiens]
Length = 1806
Score = 35.4 bits (80), Expect = 0.051
Identities = 31/84 (36%), Positives = 40/84 (47%), Gaps = 11/84 (13%)
Query: 172 AGSAAGLYPSARSMFSPYREGPIRGPCALAPNPSSERRSPRPIFDLEFHLLEPVPSSPLQ 231
AG A+G P AR + + + P+R P L P P R +P+P F E + PVPS
Sbjct: 36 AGEASGA-PPARILEA---KSPLRSPARLLPLP---RLAPKP-FSKEQDVKSPVPSLRPS 87
Query: 232 PLPPSPSPGPHARP---ELPERPP 252
PSPS G P +L R P
Sbjct: 88 STGPSPSGGLSEEPAAKDLDNRMP 111
>gi|239747180 PREDICTED: hypothetical protein XP_002343933 [Homo
sapiens]
Length = 1595
Score = 35.4 bits (80), Expect = 0.051
Identities = 31/84 (36%), Positives = 40/84 (47%), Gaps = 11/84 (13%)
Query: 172 AGSAAGLYPSARSMFSPYREGPIRGPCALAPNPSSERRSPRPIFDLEFHLLEPVPSSPLQ 231
AG A+G P AR + + + P+R P L P P R +P+P F E + PVPS
Sbjct: 36 AGEASGA-PPARILEA---KSPLRSPARLLPLP---RLAPKP-FSKEQDVKSPVPSLRPS 87
Query: 232 PLPPSPSPGPHARP---ELPERPP 252
PSPS G P +L R P
Sbjct: 88 STGPSPSGGLSEEPAAKDLDNRMP 111
>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
Length = 3571
Score = 35.4 bits (80), Expect = 0.051
Identities = 27/86 (31%), Positives = 38/86 (44%), Gaps = 8/86 (9%)
Query: 170 SAAGSAAGLYPSAR---SMFSPYREGPIRGPCALAPNPSSERRSPRPIFDLEFHLLEPVP 226
S +G++ L PS + SP E P P P+P S+ +P L +P
Sbjct: 2338 SGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQ--GTKPALPLASTSSDPPQ 2395
Query: 227 SSPLQPLPPSPSPGPHARPELPERPP 252
+S QP P P P +P+L RPP
Sbjct: 2396 ASTAQP---QPQPQPPKQPQLIGRPP 2418
Score = 33.1 bits (74), Expect = 0.25
Identities = 26/76 (34%), Positives = 30/76 (39%), Gaps = 3/76 (3%)
Query: 178 LYPSARSMFSPYREGPIRGPCALAPNPSS-ERRSPRPIFDLEFHLLEPVPSSPLQPLPPS 236
LYP + S SP P P L P P P I + L+ P +P P PP
Sbjct: 1947 LYPISPS--SPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPP 2004
Query: 237 PSPGPHARPELPERPP 252
P P P P P PP
Sbjct: 2005 PPPPPPPPPPPPSAPP 2020
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.134 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,175,967
Number of Sequences: 37866
Number of extensions: 953988
Number of successful extensions: 10136
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 148
Number of HSP's successfully gapped in prelim test: 447
Number of HSP's that attempted gapping in prelim test: 7728
Number of HSP's gapped (non-prelim): 2434
length of query: 262
length of database: 18,247,518
effective HSP length: 100
effective length of query: 162
effective length of database: 14,460,918
effective search space: 2342668716
effective search space used: 2342668716
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.