Guide to the Human Genome
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Search of human proteins with 197245373

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|197245373 proline rich 22 isoform 1 [Homo sapiens]
         (422 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|197245373 proline rich 22 isoform 1 [Homo sapiens]                 892   0.0  
gi|23503299 proline rich 22 isoform 2 [Homo sapiens]                  759   0.0  
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      60   4e-09
gi|11386183 WAS protein family, member 2 [Homo sapiens]                59   6e-09
gi|47132519 Ras association and pleckstrin homology domains 1 is...    59   8e-09
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H...    59   8e-09
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    58   2e-08
gi|56118221 amyloid beta (A4) precursor protein-binding, family ...    57   3e-08
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                     56   5e-08
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]                     56   5e-08
gi|7706501 WW domain binding protein 11 [Homo sapiens]                 55   9e-08
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          55   1e-07
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          55   1e-07
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          55   1e-07
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    54   2e-07
gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]           54   3e-07
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     54   3e-07
gi|21389357 MAPK-interacting and spindle-stabilizing protein [Ho...    54   3e-07
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]         54   3e-07
gi|163965366 nascent polypeptide-associated complex alpha subuni...    54   3e-07
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    53   5e-07
gi|160707881 formin 2 [Homo sapiens]                                   53   5e-07
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]       53   5e-07
gi|153792074 proline rich 12 [Homo sapiens]                            53   5e-07
gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens]     52   8e-07
gi|210032580 SET domain containing 1B [Homo sapiens]                   52   1e-06
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [...    51   2e-06
gi|194353976 transcription factor AP-2 epsilon (activating enhan...    51   2e-06
gi|4508017 zinc finger protein 207 isoform a [Homo sapiens]            51   2e-06
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]         50   3e-06

>gi|197245373 proline rich 22 isoform 1 [Homo sapiens]
          Length = 422

 Score =  892 bits (2305), Expect = 0.0
 Identities = 422/422 (100%), Positives = 422/422 (100%)

Query: 1   MQHPKPFCAPAAPQEGFSPQSLEGAEVLGNQPAPTCAEPPPAMGSLNLYHPPDPEKEVFP 60
           MQHPKPFCAPAAPQEGFSPQSLEGAEVLGNQPAPTCAEPPPAMGSLNLYHPPDPEKEVFP
Sbjct: 1   MQHPKPFCAPAAPQEGFSPQSLEGAEVLGNQPAPTCAEPPPAMGSLNLYHPPDPEKEVFP 60

Query: 61  APPAGFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQP 120
           APPAGFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQP
Sbjct: 61  APPAGFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQP 120

Query: 121 YLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGP 180
           YLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGP
Sbjct: 121 YLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGP 180

Query: 181 APLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGAR 240
           APLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGAR
Sbjct: 181 APLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGAR 240

Query: 241 PGVPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGAS 300
           PGVPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGAS
Sbjct: 241 PGVPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGAS 300

Query: 301 EPEGTLCEVPGPALPDSSGGNSADDIRSLCLPEELLSFDYSVPEILDTVSNVDYFFNFKA 360
           EPEGTLCEVPGPALPDSSGGNSADDIRSLCLPEELLSFDYSVPEILDTVSNVDYFFNFKA
Sbjct: 301 EPEGTLCEVPGPALPDSSGGNSADDIRSLCLPEELLSFDYSVPEILDTVSNVDYFFNFKA 360

Query: 361 LDEEQPPHPGPPATNTPAPILSGKRKASTAKKGKPGRKARQPAGPASATPPGPREDLGAT 420
           LDEEQPPHPGPPATNTPAPILSGKRKASTAKKGKPGRKARQPAGPASATPPGPREDLGAT
Sbjct: 361 LDEEQPPHPGPPATNTPAPILSGKRKASTAKKGKPGRKARQPAGPASATPPGPREDLGAT 420

Query: 421 PH 422
           PH
Sbjct: 421 PH 422


>gi|23503299 proline rich 22 isoform 2 [Homo sapiens]
          Length = 420

 Score =  759 bits (1959), Expect = 0.0
 Identities = 360/361 (99%), Positives = 360/361 (99%)

Query: 62  PPAGFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPY 121
           PP GFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPY
Sbjct: 60  PPTGFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPY 119

Query: 122 LKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPA 181
           LKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPA
Sbjct: 120 LKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPA 179

Query: 182 PLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGARP 241
           PLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGARP
Sbjct: 180 PLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGARP 239

Query: 242 GVPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASE 301
           GVPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASE
Sbjct: 240 GVPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASE 299

Query: 302 PEGTLCEVPGPALPDSSGGNSADDIRSLCLPEELLSFDYSVPEILDTVSNVDYFFNFKAL 361
           PEGTLCEVPGPALPDSSGGNSADDIRSLCLPEELLSFDYSVPEILDTVSNVDYFFNFKAL
Sbjct: 300 PEGTLCEVPGPALPDSSGGNSADDIRSLCLPEELLSFDYSVPEILDTVSNVDYFFNFKAL 359

Query: 362 DEEQPPHPGPPATNTPAPILSGKRKASTAKKGKPGRKARQPAGPASATPPGPREDLGATP 421
           DEEQPPHPGPPATNTPAPILSGKRKASTAKKGKPGRKARQPAGPASATPPGPREDLGATP
Sbjct: 360 DEEQPPHPGPPATNTPAPILSGKRKASTAKKGKPGRKARQPAGPASATPPGPREDLGATP 419

Query: 422 H 422
           H
Sbjct: 420 H 420


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 99/416 (23%), Positives = 129/416 (31%), Gaps = 125/416 (30%)

Query: 4   PKPFCAPAAPQEGFSPQSLEGAEVLGNQPAPTCAEPPPAMGSLNLYHPPDPEKEVFPAPP 63
           P+P  AP  P  G  PQ  +G       P P     P   G   +  P  P     P PP
Sbjct: 89  PQPPTAPTRPPNGQGPQGPKG------DPGPPGI--PGRNGDPGI--PGQPGSPGSPGPP 138

Query: 64  AGFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYLK 123
              +  P G    P+ Y  ++ + D+         A   GPAG P  PG     P     
Sbjct: 139 GICESCPTG----PQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPG-----PPGTSG 189

Query: 124 APGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPL 183
            PG P  P YQ  PG P    P  PP  PG      +G +GPA          ++G +  
Sbjct: 190 HPGSPGSPGYQGPPGEPGQAGPSGPPGPPGA-----IGPSGPAG---------KDGESGR 235

Query: 184 PPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGARPGV 243
           P  P +   P P                          PG          ++G    PG 
Sbjct: 236 PGRPGERGLPGP--------------------------PG----------IKGPAGIPGF 259

Query: 244 PLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASEPE 303
               PG+   +  + + G     G+  AP       LP +          +  PG   P 
Sbjct: 260 ----PGMKGHRGFDGRNGE---KGETGAPGLKGENGLPGE----------NGAPGPMGPR 302

Query: 304 GTLCEVPGPALPDSSGGNSADDIRSLCLPEELLSFDYSVPEILDTVSNVDYFFNFKALDE 363
           G   E   P LP ++G    D  R                                   +
Sbjct: 303 GAPGERGRPGLPGAAGARGNDGARG---------------------------------SD 329

Query: 364 EQPPHPGPPAT----NTPAPILSGKRKASTAKKGKPGRKARQ-PAGPASAT-PPGP 413
            QP  PGPP T     +P          S    G PG++    P G A A  PPGP
Sbjct: 330 GQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGP 385



 Score = 38.9 bits (89), Expect = 0.009
 Identities = 105/390 (26%), Positives = 117/390 (30%), Gaps = 110/390 (28%)

Query: 52   PDPEKEVFPAPPAGFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAP 111
            P    E  P  PAGF  AP G   +P          + G+          GGP GV   P
Sbjct: 797  PGERGETGPPGPAGFPGAP-GQNGEPGGKGERGAPGEKGE----------GGPPGVAGPP 845

Query: 112  GSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVEL 171
            G            P  PP P   +   G         P GPG  A GF G  G      L
Sbjct: 846  GG---------SGPAGPPGPQGVKGERGS--------PGGPG--AAGFPGARG------L 880

Query: 172  PLPPLEEGPAPLPPP---PPKENKPPPVLIT-LPAEPTLP-PDAYSHLQGHLGHFPG--- 223
            P PP   G    P P   P K+  P P   T  P  P +  P   +   G  G  PG   
Sbjct: 881  PGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGS-PGAQG 939

Query: 224  ----PEPLAFP----VKELQGSGARPGVPLYPPGLSELKVAEVKEGA--LLGAGKAKAPK 273
                P PL        + L G    PG P   PG   +K    K GA  L G      P+
Sbjct: 940  PPGAPGPLGIAGITGARGLAGPPGMPG-PRGSPGPQGVKGESGKPGANGLSGERGPPGPQ 998

Query: 274  TARALALPDKVLLEDAMKLFDCLPGASEPEGTLCEVPGPALPDSSGGNSADDIRSLCLPE 333
                LA        D     D LPG     G   +      P + G              
Sbjct: 999  GLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGA------------- 1045

Query: 334  ELLSFDYSVPEILDTVSNVDYFFNFKALDEEQPPHPGPPATNTPAPILSGKRKAS--TAK 391
                                            P HPGPP    PA   SG R  S     
Sbjct: 1046 --------------------------------PGHPGPPGPVGPAG-KSGDRGESGPAGP 1072

Query: 392  KGKPGRKARQPAGPASAT-PPGPREDLGAT 420
             G PG     PAG   A  P GPR D G T
Sbjct: 1073 AGAPG-----PAGSRGAPGPQGPRGDKGET 1097



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 24/68 (35%), Positives = 30/68 (44%), Gaps = 6/68 (8%)

Query: 103 GPAGVPSAPGSYLLE----PQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALG 158
           GPAG P + G+        PQ +  A G P  P    +PGG   + P   P  PG   +G
Sbjct: 354 GPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPG--LMG 411

Query: 159 FVGDAGPA 166
             G  GPA
Sbjct: 412 ARGPPGPA 419



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 39/149 (26%), Positives = 47/149 (31%), Gaps = 18/149 (12%)

Query: 103 GPAGVPSAPGSYLLEPQPYLKAP-GLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVG 161
           GP G+P   G       P    P G    P     PGGP        P GPG +      
Sbjct: 495 GPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGK---- 550

Query: 162 DAGPAAFVELPLPPLEEGPAPLP-PPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGH 220
                     P PP  +G +  P PP P   +  P ++  P       D      G  G 
Sbjct: 551 ----------PGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPK--GNDGAPGKNGERGG 598

Query: 221 FPGPEPLAFPVKELQGSGARPGVPLYPPG 249
             GP P   P K  +     P  P  P G
Sbjct: 599 PGGPGPQGPPGKNGETGPQGPPGPTGPGG 627



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 67/250 (26%), Positives = 83/250 (33%), Gaps = 48/250 (19%)

Query: 103  GPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEG-PG-PEALGFV 160
            GPAG   APG     P     APG P  P   +   G +         G PG P A G  
Sbjct: 1068 GPAGPAGAPG-----PAGSRGAPG-PQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSP 1121

Query: 161  GDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGH 220
            G AG    +  P P    GP     PP K+                         GH G 
Sbjct: 1122 GPAGQQGAIGSPGPAGPRGPVGPSGPPGKDG----------------------TSGHPGP 1159

Query: 221  FPGPEPLA-FPVKELQGSGARPGV--PLYPPGLSELKVAEVKEGALLGAGKAKAPKTARA 277
               P P      +  +GS   PG   P  PPG        V   A+ G G  KA   A  
Sbjct: 1160 IGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEKAGGFAPY 1219

Query: 278  LA---LPDKVLLEDAMKLFDCLPGASEPEGTLCEVPGPALPDSSGGNSADDIRSL--CLP 332
                 +  K+  ++ M     + G         ++     PD S  N A + R L  C P
Sbjct: 1220 YGDEPMDFKINTDEIMTSLKSVNG---------QIESLISPDGSRKNPARNCRDLKFCHP 1270

Query: 333  EELLSFDYSV 342
             EL S +Y V
Sbjct: 1271 -ELKSGEYWV 1279



 Score = 30.0 bits (66), Expect = 4.1
 Identities = 69/261 (26%), Positives = 77/261 (29%), Gaps = 48/261 (18%)

Query: 98  AASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPG---- 153
           A    G AG P   G   L   P L+    PP P   +   GP       PP   G    
Sbjct: 670 APGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPP-----GPPGAAGTPGL 724

Query: 154 ---PEALGFVGDAGPAAFVELPLPPLEEG-PAPLPPPPPKENKPPPVLITLPAE------ 203
              P   G +G  GP      P  P  +G P    P  P     PP     P +      
Sbjct: 725 QGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGA 784

Query: 204 PTLPPDAYSH-LQGHLGHFPGPEPLAFPVKELQ----------------GSGARPGV--- 243
           P LP  A      G  G    P P  FP    Q                G G  PGV   
Sbjct: 785 PGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGP 844

Query: 244 -----PLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPG 298
                P  PPG   +K    + G+  G G A  P  AR L  P               PG
Sbjct: 845 PGGSGPAGPPGPQGVK---GERGSPGGPGAAGFP-GARGLPGPPGSNGNPGPPGPSGSPG 900

Query: 299 ASEPEGTLCEVPGPALPDSSG 319
              P G       P  P  SG
Sbjct: 901 KDGPPGPAGNTGAPGSPGVSG 921


>gi|11386183 WAS protein family, member 2 [Homo sapiens]
          Length = 498

 Score = 59.3 bits (142), Expect = 6e-09
 Identities = 55/206 (26%), Positives = 70/206 (33%), Gaps = 52/206 (25%)

Query: 9   APAAPQEGFSPQSLEGAEVLGNQPAPTCAEPPPAMGSLNLYHPPDPEKEVFPAPPAGFQM 68
           +P+  ++   P   E +  + NQ     A P  +   ++  HPP       PAPP G   
Sbjct: 259 SPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRS-SVVSPSHPP-------PAPPLGSPP 310

Query: 69  APCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPY---LKAP 125
            P   F  P                          PA  P  P    + P P      +P
Sbjct: 311 GPKPGFAPP--------------------------PAPPPPPPPMIGIPPPPPPVGFGSP 344

Query: 126 GLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEE---GPAP 182
           G PP P     P  P F  P  PP  P             A +  LP PPL +   G  P
Sbjct: 345 GTPPPPSPPSFPPHPDFAAPPPPPPPPA------------ADYPTLPPPPLSQPTGGAPP 392

Query: 183 LPPPPPKENKPPPVLITLPAEPTLPP 208
            PPPPP    PPP       +P +PP
Sbjct: 393 PPPPPPPPGPPPPPFTGADGQPAIPP 418



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 42/126 (33%), Positives = 44/126 (34%), Gaps = 5/126 (3%)

Query: 128 PPYPHYQQAPGG-PQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPP 186
           PP P     PG  P F  P  PP  P P  +G      P  F     PP    P   PP 
Sbjct: 301 PPAPPLGSPPGPKPGFAPPPAPPPPP-PPMIGIPPPPPPVGFGSPGTPP-PPSPPSFPPH 358

Query: 187 PPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGARPGVPLY 246
           P     PPP        PTLPP   S   G  G  P P P   P           G P  
Sbjct: 359 PDFAAPPPPPPPPAADYPTLPPPPLSQPTG--GAPPPPPPPPPPGPPPPPFTGADGQPAI 416

Query: 247 PPGLSE 252
           PP LS+
Sbjct: 417 PPPLSD 422



 Score = 28.9 bits (63), Expect = 9.2
 Identities = 22/92 (23%), Positives = 35/92 (38%), Gaps = 13/92 (14%)

Query: 333 EELLSFDYSVPEILDTVSNVDYFFNFKALDEEQPPHPGP---PATNTPAPILSGKRKAST 389
           E + +  Y  P   D+ S+    F+    ++  PP P     P  N     L+G +++S 
Sbjct: 239 ENVDASSYPPPPQSDSASSPSPSFS----EDNLPPPPAEFSYPVDNQRGSGLAGPKRSSV 294

Query: 390 AKKGKPGRKARQPAGPASATPPGPREDLGATP 421
                P      P  P   +PPGP+      P
Sbjct: 295 VSPSHP------PPAPPLGSPPGPKPGFAPPP 320


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 58.9 bits (141), Expect = 8e-09
 Identities = 99/412 (24%), Positives = 133/412 (32%), Gaps = 52/412 (12%)

Query: 5   KPFCAPAAPQEGFSPQSLEGAEVLGNQPAPTCAEPPPAMGSLNLYHPPDPEKEVFPAPPA 64
           +P+ +   P    SPQ         +QP+P    PPP         PP P     P PP 
Sbjct: 600 RPYTSLVPP---LSPQPKIVTPYTASQPSPPLPPPPPPP-------PPPPPPPPPPPPPL 649

Query: 65  GFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAP--GSYLLEPQPYL 122
             Q AP      P   +    T       L   +  SG     P+ P   S  ++PQ  +
Sbjct: 650 PSQSAPSAGSAAPMFVKYSTIT------RLQNASQHSGALFKPPTPPVMQSQSVKPQILV 703

Query: 123 KAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELP-----LPPLE 177
              G+ P P     P  P   +    P    P    F     P    ++       PP  
Sbjct: 704 PPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTP 763

Query: 178 EGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLA-----FPVK 232
             P P+P P P +  P P L+T+PA  +    A    Q        P P A     FP  
Sbjct: 764 PPPPPIPAPLPPQAPPKP-LVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPAS 822

Query: 233 ELQGSGARPGVPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKL 292
            +  S   P VP+ PP L + +           +  AK P +  +   P   +++     
Sbjct: 823 YIPPSPPTPPVPVPPPTLPKQQ-----------SFCAKPPPSPLS---PVPSVVKQIASQ 868

Query: 293 FDCLPGASEPEGT-LCEVPGPALPDSSGGNSADDI-RSLCLPEELLSFDYSVPEILDTVS 350
           F   P     E   L  VP    P S     A    +   +P     F    PE      
Sbjct: 869 FPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPES----- 923

Query: 351 NVDYFFNFKALDEEQPPHPGPPATNTPAPILSGKRKASTAKKGKPGRKARQP 402
                F          P P PP T +P P  SG     T+K   PG K   P
Sbjct: 924 --SLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPP 973



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 53/193 (27%), Positives = 67/193 (34%), Gaps = 23/193 (11%)

Query: 4   PKPFCAPAAPQ--EGFSPQSLEGAEVLGNQPAPTCAEPPPAMGSLNLYHPPDPEKEVFPA 61
           PKP     AP   +  +P   + A      P P   + P    S   Y PP P     P 
Sbjct: 779 PKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPAS---YIPPSPPTPPVPV 835

Query: 62  PPAGFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPY 121
           PP         C   P        +P     ++ K  AS   P   P A  S  L+P P 
Sbjct: 836 PPPTLPKQQSFCAKPP-------PSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPA 888

Query: 122 LKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPA 181
             AP  PP    +  P      +P   P+ P P          P + +  P PP    PA
Sbjct: 889 NVAPQSPPA--VKAKPKWQPSSIPVPSPDFPPPP---------PESSLVFPPPPPSPVPA 937

Query: 182 PLPPPPPKENKPP 194
           P PPPPP  +  P
Sbjct: 938 PPPPPPPTASPTP 950



 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 94/396 (23%), Positives = 133/396 (33%), Gaps = 60/396 (15%)

Query: 4    PKPFCAPAAPQEGFSPQSLEGAEV--LGNQPAPTCAEPPPAMGSLNLYHPPDPEKEVFPA 61
            P P CAP+ PQ    P  L+  +V  +     PT   PPP    L    PP P   + PA
Sbjct: 730  PAP-CAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTI-PA 787

Query: 62   PPAGFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPS----APGSYLLE 117
            P +   +AP      P        TP +  +       +S  P   P+     P   L +
Sbjct: 788  PTSTKTVAPVVTQAAPPT-----PTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPK 842

Query: 118  PQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEAL---------GFVGDAGPAAF 168
             Q +   P  PP P     P   + +   FPP  P P A+           V    P A 
Sbjct: 843  QQSFCAKP--PPSP-LSPVPSVVKQIASQFPPP-PTPPAMESQPLKPVPANVAPQSPPAV 898

Query: 169  VELPLPPLEEGPAPLP--PPPPKENK---PPPVLITLPAEPTLPPDAYSHLQGHLGHFPG 223
               P       P P P  PPPP E+    PPP    +PA P  PP               
Sbjct: 899  KAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPP--------------- 943

Query: 224  PEPLAFPVKELQGSGARPGVPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDK 283
              P A P  +  GS  +       PG  +      +  ++  +  A+ P+       P +
Sbjct: 944  --PTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPE-------PKR 994

Query: 284  VLLEDAMKLFDCLPGASEPEGTLCEVPGPALPDSSGGNSADDIRSLCLPEELLSFDYSVP 343
              ++  +  F   P A     +   +P PA P   G  +   +    LP  L     S  
Sbjct: 995  PSVDSLVSKF--TPPAESGSPSKETLPPPAAPPKPGKLNLSGVN---LPGVLQQGCVSAK 1049

Query: 344  EILDTVSNVDYFFNFKALDEEQPPHPGPPATNTPAP 379
              + +    D    F +   +    P PP T  P P
Sbjct: 1050 APVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLP 1085



 Score = 34.3 bits (77), Expect = 0.22
 Identities = 56/214 (26%), Positives = 74/214 (34%), Gaps = 39/214 (18%)

Query: 5    KPFCAPAA---PQEGFSPQSLEGAEVLGNQP-APTCAEPPPAMGSLNLYHPPDPEKEVFP 60
            KP   P++   P   F P   E + V    P +P  A PPP   + +    P P+K   P
Sbjct: 901  KPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTAS----PTPDKSGSP 956

Query: 61   APPAGFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPG-----SYL 115
                    +P G    P        TP    S    + +SSG     P  P      S  
Sbjct: 957  GKKTSKTSSPGGKKPPP--------TPQRNSS----IKSSSGAEHPEPKRPSVDSLVSKF 1004

Query: 116  LEP-------QPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAF 168
              P       +  L  P  PP P      G     LP    +G        +   G  + 
Sbjct: 1005 TPPAESGSPSKETLPPPAAPPKPGKLNLSG---VNLPGVLQQGCVSAKAPVLSGRGKDSV 1061

Query: 169  VELPLPPLEEGPAPLPPPPPKENKPPPVLITLPA 202
            VE P PP +   +  PPPPP E + P   I +PA
Sbjct: 1062 VEFPSPPSD---SDFPPPPP-ETELPLPPIEIPA 1091


>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
           sapiens]
          Length = 309

 Score = 58.9 bits (141), Expect = 8e-09
 Identities = 67/210 (31%), Positives = 79/210 (37%), Gaps = 19/210 (9%)

Query: 2   QHPKPFCAPAAPQEGFSPQSLEGAEVLGNQPAPTCAE-PPPAMGSLNLYHPPDPEKEVFP 60
           Q P P   P  P EG  PQ   G +  G  P P   E PPP  G+ +   PP P K   P
Sbjct: 90  QGPPP--RPGKP-EGQPPQG--GNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGP 144

Query: 61  APPAGFQ-MAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQ 119
            P  G Q   P      PR  + E   P  G  +        G P G P   G+    P 
Sbjct: 145 PPQGGNQSQGP-----PPRPGKPEGPPPQGGNQSQGP-PPHPGKPEGPPPQGGNQSQGPP 198

Query: 120 PYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPL-PPLEE 178
           P    P  PP     Q+ G P       P +  GP + G     GP      P  PP +E
Sbjct: 199 PRPGKPEGPPPQGGNQSQGPPPR-----PGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQE 253

Query: 179 GPAPLPPPPPKENKPPPVLITLPAEPTLPP 208
           G  P  PPPP   + PP     P +P  PP
Sbjct: 254 GNKPQRPPPPGRPQGPPPPGGNPQQPLPPP 283



 Score = 55.8 bits (133), Expect = 7e-08
 Identities = 64/198 (32%), Positives = 76/198 (38%), Gaps = 30/198 (15%)

Query: 2   QHPKPFCAPAAPQEGFSPQSLEGAEVLGNQPAPTCAE-PPPAMGSLNLYHPPDPEKEVFP 60
           Q P P   P  P EG  PQ   G +  G  P P   E PPP  G+ +   PP P K   P
Sbjct: 132 QGPPP--RPGKP-EGPPPQG--GNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGP 186

Query: 61  APPAGFQ-MAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQ 119
            P  G Q   P      PR  + E   P  G  +        G P G PS  G+      
Sbjct: 187 PPQGGNQSQGP-----PPRPGKPEGPPPQGGNQSQGP-PPRPGKPEGPPSQGGN------ 234

Query: 120 PYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEG 179
              K  G PP+P   Q P   +   P  PP    P+     G   P    + PLPP   G
Sbjct: 235 ---KPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQ-----GPPPPGGNPQQPLPP-PAG 285

Query: 180 PAPLPPPPPKENKP--PP 195
               PPPPP+  +P  PP
Sbjct: 286 KPQGPPPPPQGGRPHRPP 303



 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 65/200 (32%), Positives = 74/200 (37%), Gaps = 24/200 (12%)

Query: 2   QHPKPFCAPAAPQEGFSPQSLEGAEVLGNQPAPTCAE-PPPAMGSLNLYHPPDPEKEVFP 60
           Q P P   P  P EG  PQ   G +  G  P P   E PPP  G+ +   PP P K   P
Sbjct: 111 QGPPP--RPGKP-EGPPPQG--GNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGP 165

Query: 61  APPAGFQ-MAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQ 119
            P  G Q   P      P   + E   P  G  +        G P G P   G+    P 
Sbjct: 166 PPQGGNQSQGP-----PPHPGKPEGPPPQGGNQSQGP-PPRPGKPEGPPPQGGNQSQGPP 219

Query: 120 PYLKAPGLPPYPHYQ--QAPGGPQFLLPYFP--PEGPGPEALGFVGDAGPAAFVELPLPP 175
           P    PG P  P  Q    P GP    P  P  P+GP P+         P    + P PP
Sbjct: 220 P---RPGKPEGPPSQGGNKPQGP----PPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPP 272

Query: 176 LEEGPAPLPPPPPKENKPPP 195
                 PLPPP  K   PPP
Sbjct: 273 GGNPQQPLPPPAGKPQGPPP 292



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 78/331 (23%), Positives = 96/331 (29%), Gaps = 95/331 (28%)

Query: 102 GGPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVG 161
           G P G P   G+    P P    P  PP     Q+ G P        PEG  P+  G   
Sbjct: 55  GKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPP---RPGKPEGQPPQ--GGNQ 109

Query: 162 DAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQG---HL 218
             GP      P P   EGP   PP    +++ PP     P  P  PP   +  QG     
Sbjct: 110 SQGPP-----PRPGKPEGP---PPQGGNQSQGPPPRPGKPEGP--PPQGGNQSQGPPPRP 159

Query: 219 GHFPGPEPLAFPVKELQGSGARPGVPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARAL 278
           G   GP P      + QG    PG P  PP           +G     GK + P      
Sbjct: 160 GKPEGPPPQGG--NQSQGPPPHPGKPEGPPPQG----GNQSQGPPPRPGKPEGPPPQ--- 210

Query: 279 ALPDKVLLEDAMKLFDCLPGASEPEGTLCEVPGPALPDSSGGNSADDIRSLCLPEELLSF 338
                              G ++ +G       P  P S GGN                 
Sbjct: 211 -------------------GGNQSQGPPPRPGKPEGPPSQGGNKP--------------- 236

Query: 339 DYSVPEILDTVSNVDYFFNFKALDEEQPPHPGPPATNTPAPILSGKRKASTAKKGKP--- 395
                                   +  PPHPG P    P     G +       G+P   
Sbjct: 237 ------------------------QGPPPHPGKPQGPPPQ---EGNKPQRPPPPGRPQGP 269

Query: 396 ---GRKARQPAGPASATPPG-PREDLGATPH 422
              G   +QP  P +  P G P    G  PH
Sbjct: 270 PPPGGNPQQPLPPPAGKPQGPPPPPQGGRPH 300


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 102/365 (27%), Positives = 120/365 (32%), Gaps = 101/365 (27%)

Query: 10  PAAPQEGFSPQSLEGAEVLGNQPAPTCA-EPPPAM------GSLNLYHPPDPEKEVFPA- 61
           PAAP EG                AP  A EPPPA       G      PP P + + PA 
Sbjct: 75  PAAPAEG----------------APGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAG 118

Query: 62  ---PPAGFQMAPCG----CFFDPRIYRIEWTTPDLGQSALYK------LAASSGGPAGVP 108
              P A  +  P G    C   P    +    P+   +   K      LAA +G   G  
Sbjct: 119 PAPPAAKLRPPPEGSAGSCAPVPAAAAVA-AGPEPAPAGPAKPAGPAALAARAGPGPGPG 177

Query: 109 SAPGSYLLEPQPYLKAPGLPPYP---------------HYQQAPG------GPQFLLPYF 147
             PG     P P    PG P  P               H+  AP       GP  LLP  
Sbjct: 178 PGPG-----PGP---GPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLP 229

Query: 148 PPEGPGP--EALGFVGDAGPAAFVELPLPPLE---EGPAPLPPPPPKENKPPPVLITLP- 201
            P  PG   +   FVG A P A    P PP       PA  PPPPP    P P  +  P 
Sbjct: 230 KPAAPGTVIQTPPFVGAAAPPA-PAAPSPPAAPAPAAPAAAPPPPP----PAPATLARPP 284

Query: 202 --------AEPTLPPDAYSHLQGHLGHFPGPEPLA---FPVKELQGSGARPGVPLYPPGL 250
                   A P +PP A +   G  G  P P P A     V    G GA    P   PG+
Sbjct: 285 GHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAP--APGV 342

Query: 251 SELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASEPEGTLCEVP 310
                  V +          AP  A+ LA         +M +   + GA  P       P
Sbjct: 343 KAESPKRVVQA---------APPAAQTLAASGPASTAASMVIGPTMQGAL-PSPAAVPPP 392

Query: 311 GPALP 315
            P  P
Sbjct: 393 APGTP 397



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 56/187 (29%), Positives = 63/187 (33%), Gaps = 23/187 (12%)

Query: 6   PFCAPAAPQEGFSPQSLEGAEVLGNQPAPTCAEPP--PAMGSLNLYHPPDPEKEVFPAPP 63
           P   PAAP          GA      PAP    PP  PA  +     PP P      A P
Sbjct: 227 PLPKPAAPGTVIQTPPFVGAAA---PPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARP 283

Query: 64  AGFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPS--APGSYLLEPQPY 121
            G    P      P +             A    A ++GGPAGV     PG+    P P 
Sbjct: 284 PGHPAGPPTA--APAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPG 341

Query: 122 LKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPA 181
           +KA    P    Q AP   Q L       GP   A   V   GP     LP       PA
Sbjct: 342 VKAES--PKRVVQAAPPAAQTL----AASGPASTAASMV--IGPTMQGALP------SPA 387

Query: 182 PLPPPPP 188
            +PPP P
Sbjct: 388 AVPPPAP 394



 Score = 37.0 bits (84), Expect = 0.034
 Identities = 44/139 (31%), Positives = 48/139 (34%), Gaps = 34/139 (24%)

Query: 98  AASSGGPAGVPSAPGSYLLEPQPYLKA---------PGLPPYPHYQQAPGGPQ----FLL 144
           AA +G  A    APG+   EP P  +A         PG PP P     P GP      L 
Sbjct: 70  AAGAGPAAPAEGAPGA-APEPPPAGRARPGGGGPQRPG-PPSPRRPLVPAGPAPPAAKLR 127

Query: 145 PYFPPEG-----------------PGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPPP 187
           P  PPEG                 P P   G    AGPAA      P    GP P P P 
Sbjct: 128 P--PPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPG 185

Query: 188 PKENKPPPVLITLPAEPTL 206
           P +   P    TL     L
Sbjct: 186 PGKPAGPGAAQTLNGSAAL 204



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 59/236 (25%), Positives = 76/236 (32%), Gaps = 31/236 (13%)

Query: 179 GPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSG 238
           G A   P  P E  P        A P  PP   +   G     PGP     P+  +    
Sbjct: 69  GAAGAGPAAPAEGAPG-------AAPEPPPAGRARPGGGGPQRPGPPSPRRPL--VPAGP 119

Query: 239 ARPGVPLYPPGLSEL-KVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLP 297
           A P   L PP        A V   A + AG   AP      A P  +            P
Sbjct: 120 APPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPG-----P 174

Query: 298 GASEPEGTLCEVPGPALPDSSGGNSADDIRSLCLPEELLSFDYSVPEILDTVSNVDYFFN 357
           G     G     PGP     +G  +A  +        LL+  ++    +  V+N      
Sbjct: 175 GPGPGPG-----PGPGPGKPAGPGAAQTLNGSAA---LLNSHHAAAPAVSLVNNGPAAL- 225

Query: 358 FKALDEEQPPHPGPPATNTPAPILSGKRKASTAKKGKPGRKARQPAGPASATPPGP 413
              L   +P  PG     TP P +      + A    P   A  PA PA+A PP P
Sbjct: 226 ---LPLPKPAAPGT-VIQTP-PFVGAAAPPAPAAPSPPAAPA--PAAPAAAPPPPP 274


>gi|56118221 amyloid beta (A4) precursor protein-binding, family B,
           member 1 interacting protein [Homo sapiens]
          Length = 666

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 61/195 (31%), Positives = 77/195 (39%), Gaps = 36/195 (18%)

Query: 33  APTCAEPPPAMGSLNLYHPPDPEKEVFPAPPAGFQMAPCGCFFDPRIYRIEWTTPDLGQS 92
           A T  +  PA+G+   +H  DP     P  P      P      P + R    + D   S
Sbjct: 487 AETSKDKKPALGN---HH--DPAVPRAPHAPKSSLPPP------PPVRR----SSDTSGS 531

Query: 93  ALYKLAASSGGPAGVPSAPGSYLLEPQPY--LKAPGLPPYPHYQQAPGGPQFLLPYFPPE 150
               L A   G  G+P+ P  +L  P P   L  P LPP P        P F+ P  PP+
Sbjct: 532 PATPLKAKGTGGGGLPAPPDDFLPPPPPPPPLDDPELPPPP--------PDFMEP--PPD 581

Query: 151 GPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDA 210
              P    + G AG     ELP PP    PAP P P P   +PPP    +   P +PP  
Sbjct: 582 FVPPPPPSYAGIAGS----ELPPPP-PPPPAPAPAPVPDSARPPP---AVAKRPPVPPKR 633

Query: 211 YSHLQGHLGHFPGPE 225
             +  GH G   G E
Sbjct: 634 QEN-PGHPGGAGGGE 647



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 39/132 (29%), Positives = 48/132 (36%), Gaps = 20/132 (15%)

Query: 131 PHYQQAPGGPQFLLPYFPP-------EGPGPEALGFVGDAG------PAAFVELPLPPLE 177
           P   +AP  P+  LP  PP        G     L   G  G      P  F+  P PP  
Sbjct: 503 PAVPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPPP 562

Query: 178 EGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQG-HLGHFPGPEPLAFPVKELQG 236
                LPPPPP   +PPP  +        PP +Y+ + G  L   P P P   P      
Sbjct: 563 LDDPELPPPPPDFMEPPPDFV------PPPPPSYAGIAGSELPPPPPPPPAPAPAPVPDS 616

Query: 237 SGARPGVPLYPP 248
           +   P V   PP
Sbjct: 617 ARPPPAVAKRPP 628



 Score = 29.3 bits (64), Expect = 7.0
 Identities = 17/47 (36%), Positives = 18/47 (38%), Gaps = 2/47 (4%)

Query: 364 EQPPHPGPPATNTPAPILSGKRKASTAKKGKPGRKARQ--PAGPASA 408
           E PP P PP    PAP+    R      K  P    RQ  P  P  A
Sbjct: 597 ELPPPPPPPPAPAPAPVPDSARPPPAVAKRPPVPPKRQENPGHPGGA 643


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 54/172 (31%), Positives = 61/172 (35%), Gaps = 32/172 (18%)

Query: 97  LAASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPYP------HYQQAPGGPQFLLP----- 145
           L   SG     P APG     P P    P  PP P           PGG     P     
Sbjct: 579 LPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSG 638

Query: 146 --YFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPPPP----KENKPPPVLIT 199
               PP  P PE +G    +       +P PP   G A +PPPPP        PPP    
Sbjct: 639 DATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPP-PP 697

Query: 200 LPAEPTLPPDAYSHLQGHLGHFPG-PEPLAFPVKELQGSGARPGVPLYPPGL 250
           LP E  +PP       G     PG P P  FP          PG+P  PPG+
Sbjct: 698 LPGEAGMPPPPPPLPGG-----PGIPPPPPFP--------GGPGIPPPPPGM 736



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 54/184 (29%), Positives = 63/184 (34%), Gaps = 24/184 (13%)

Query: 35  TCAEPPPAMGSLNLYHPPDPEKEVFPAPPAGFQMA-----PCGCFFDPRIYRIEWTTPDL 89
           T   PPPA G      PP P     P  P G  ++     P G    P         P L
Sbjct: 585 TIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISP--------PPPL 636

Query: 90  GQSALYKLAASSGGPAGVPSA---PGSYLLEPQPYLKAPG-LPPYPHYQQAPGGPQFLLP 145
              A            G+PS    PG   + P P L     +PP P       G    +P
Sbjct: 637 SGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAG----IP 692

Query: 146 YFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPPPPKEN--KPPPVLITLPAE 203
             PP  PG   +       P      P PP   GP  +PPPPP      PPP    +PA 
Sbjct: 693 PPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPG-IPPPPPGMGMPPPPPFGFGVPAA 751

Query: 204 PTLP 207
           P LP
Sbjct: 752 PVLP 755



 Score = 30.0 bits (66), Expect = 4.1
 Identities = 27/93 (29%), Positives = 34/93 (36%), Gaps = 14/93 (15%)

Query: 171 LPLPPLEEGPAPLPPPPPKENK-----PPPVL---ITLPAEPTLPPDAYSHLQGHL---- 218
           + +PP     AP+PP PP         PPP      T P  P  PP     L G +    
Sbjct: 561 ITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISS 620

Query: 219 -GHFPGPEPLAFPVKELQGSGARPGVPLYPPGL 250
               PG   ++ P   L G    P  P  P G+
Sbjct: 621 PPSLPGGTAIS-PPPPLSGDATIPPPPPLPEGV 652


>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
          Length = 1272

 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 54/172 (31%), Positives = 61/172 (35%), Gaps = 32/172 (18%)

Query: 97  LAASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPYP------HYQQAPGGPQFLLP----- 145
           L   SG     P APG     P P    P  PP P           PGG     P     
Sbjct: 588 LPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSG 647

Query: 146 --YFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPPPP----KENKPPPVLIT 199
               PP  P PE +G    +       +P PP   G A +PPPPP        PPP    
Sbjct: 648 DATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPP-PP 706

Query: 200 LPAEPTLPPDAYSHLQGHLGHFPG-PEPLAFPVKELQGSGARPGVPLYPPGL 250
           LP E  +PP       G     PG P P  FP          PG+P  PPG+
Sbjct: 707 LPGEAGMPPPPPPLPGG-----PGIPPPPPFP--------GGPGIPPPPPGM 745



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 54/184 (29%), Positives = 63/184 (34%), Gaps = 24/184 (13%)

Query: 35  TCAEPPPAMGSLNLYHPPDPEKEVFPAPPAGFQMA-----PCGCFFDPRIYRIEWTTPDL 89
           T   PPPA G      PP P     P  P G  ++     P G    P         P L
Sbjct: 594 TIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISP--------PPPL 645

Query: 90  GQSALYKLAASSGGPAGVPSA---PGSYLLEPQPYLKAPG-LPPYPHYQQAPGGPQFLLP 145
              A            G+PS    PG   + P P L     +PP P       G    +P
Sbjct: 646 SGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAG----IP 701

Query: 146 YFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPPPPKEN--KPPPVLITLPAE 203
             PP  PG   +       P      P PP   GP  +PPPPP      PPP    +PA 
Sbjct: 702 PPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPG-IPPPPPGMGMPPPPPFGFGVPAA 760

Query: 204 PTLP 207
           P LP
Sbjct: 761 PVLP 764



 Score = 30.0 bits (66), Expect = 4.1
 Identities = 27/93 (29%), Positives = 34/93 (36%), Gaps = 14/93 (15%)

Query: 171 LPLPPLEEGPAPLPPPPPKENK-----PPPVL---ITLPAEPTLPPDAYSHLQGHL---- 218
           + +PP     AP+PP PP         PPP      T P  P  PP     L G +    
Sbjct: 570 ITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISS 629

Query: 219 -GHFPGPEPLAFPVKELQGSGARPGVPLYPPGL 250
               PG   ++ P   L G    P  P  P G+
Sbjct: 630 PPSLPGGTAIS-PPPPLSGDATIPPPPPLPEGV 661


>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score = 55.5 bits (132), Expect = 9e-08
 Identities = 57/174 (32%), Positives = 67/174 (38%), Gaps = 13/174 (7%)

Query: 99  ASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGP--EA 156
           ASS   A   S P S +  P P    P L P P     P GP   LP  PP G  P    
Sbjct: 386 ASSQQQAPPQSVPPSQIQAP-PMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRP 444

Query: 157 LGFVGDAGPAAFVELPLPPLEEGPAPLPPPPP-----KENKPPPVLITLPAEPTLPPDAY 211
            G  G  GP   +  P PP    P P P PPP        + PP  +  PA P +PP   
Sbjct: 445 PGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRP 504

Query: 212 SHLQGHLGHFPGPEPLA-FPVKELQGSGARPGVPLYPPGLSELKVAEVKEGALL 264
             ++  L    GP P   FP   L      PGV   PP L +   A+    A +
Sbjct: 505 GMMRPPLVPPLGPAPPGLFPPAPL----PNPGVLSAPPNLIQRPKADDTSAATI 554



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 58/201 (28%), Positives = 68/201 (33%), Gaps = 61/201 (30%)

Query: 11  AAPQEGFSPQSLEGAEVLGN-QPAPTCAEPPPAMGSLNLYHPPDPEKEVFPAPPAGFQMA 69
           A+ Q+   PQS+  +++     P P    PPPA        PP P   + P PP G    
Sbjct: 386 ASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPP----LRPPGPPTGLPPGPPPG---- 437

Query: 70  PCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYLKAPGLPP 129
                  P   R                      P G+P   G     P P L  PG PP
Sbjct: 438 ------APPFLR----------------------PPGMPGLRG-----PLPRLLPPGPPP 464

Query: 130 YPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPPPPK 189
                  PG P  L P  PP GP P                  LPP    P  +PPP P 
Sbjct: 465 GRPPGPPPGPPPGLPPGPPPRGPPPR-----------------LPP--PAPPGIPPPRPG 505

Query: 190 ENKPPPVLITLPAEPTLPPDA 210
             +PP V    PA P L P A
Sbjct: 506 MMRPPLVPPLGPAPPGLFPPA 526



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 18/49 (36%), Positives = 18/49 (36%), Gaps = 1/49 (2%)

Query: 366 PPHPGPPATNTPA-PILSGKRKASTAKKGKPGRKARQPAGPASATPPGP 413
           PP   PP    P  P L G           PGR    P GP    PPGP
Sbjct: 434 PPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGP 482


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 109/391 (27%), Positives = 134/391 (34%), Gaps = 83/391 (21%)

Query: 32  PAPTCAEPPPAMGSLNLYHPPDPEKEVFPAPPAGFQMAPCGCFFDPRIYRIEWTTPDLGQ 91
           P P+    PP         P  P+    P P    Q AP      P+  R     P    
Sbjct: 212 PTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPA---LHPQ--RPPSPHPPPHP 266

Query: 92  SALYKLAASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQA------PGGPQ-FLL 144
           S    L   +G  AG PSAP       QP L   G PP PH  QA      PG PQ F L
Sbjct: 267 SPHPPLQPLTGS-AGQPSAPS----HAQPPLHGQG-PPGPHSLQAGPLLQHPGPPQPFGL 320

Query: 145 PYFPPEGPGPEALGFVGDAG-PAAFVELPL---------PPLEE--GPAPL------PP- 185
           P  P    G   LG    A  P   ++LP          PP E+   PAPL      PP 
Sbjct: 321 P--PQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPP 378

Query: 186 -------PPPKENKPPPVL---------ITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAF 229
                  P P+ +K PP L           LP  P L P   S L  H  H P   P   
Sbjct: 379 TTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKP--LSSLSTH--HPPSAHPP-- 432

Query: 230 PVKELQGSGARPGVPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDA 289
           P++ +  S   P  P  PPGL+        +   L    A  P T      P     +  
Sbjct: 433 PLQLMPQSQPLPSSPAQPPGLT--------QSQNLPPPPASHPPTGLHQVAPQPPFAQHP 484

Query: 290 MKLFDCLPGASEPEGTLCEVPGPALPDSSGGNSAD-DIRSLCLPEELLSFDYSVPEILDT 348
                 +PG   P  T    P  + P +  G SA             ++   S P  L T
Sbjct: 485 F-----VPGGPPPI-TPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCP--LPT 536

Query: 349 VSNVDYFFNFKALDEEQPPHPGPPATNTPAP 379
           V         +ALD+ + P   PP   +P+P
Sbjct: 537 VQ-----IKEEALDDAEEPESPPPPPRSPSP 562



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 58/234 (24%), Positives = 81/234 (34%), Gaps = 68/234 (29%)

Query: 12  APQEGFSPQSLEGAEVLG---NQPAPTCAEPPPAMGSLNLYHPPD---------PEKEVF 59
           APQ    P  L G        N P P   +P   + SL+ +HPP          P+ +  
Sbjct: 387 APQAHKHPPHLSGPSPFSMNANLPPPPALKP---LSSLSTHHPPSAHPPPLQLMPQSQPL 443

Query: 60  PAPPAGFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQ 119
           P+ PA                      P L QS       +S  P G+      + + PQ
Sbjct: 444 PSSPA--------------------QPPGLTQSQNLPPPPASHPPTGL------HQVAPQ 477

Query: 120 PYLKAPGLPPYPHYQQAPGGPQFLLP------YFPPEGPG----PEALGFVGDAG----- 164
           P        P+  +   PGGP  + P        PP GPG    P   G     G     
Sbjct: 478 P--------PFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGG 529

Query: 165 ---PAAFVELPLPPLEEGPAP-LPPPPPKENKPPPVLITLPAEPTLPPDAYSHL 214
              P   V++    L++   P  PPPPP+   P P ++  P+  +     Y HL
Sbjct: 530 SSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHL 583



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 84/322 (26%), Positives = 109/322 (33%), Gaps = 55/322 (17%)

Query: 99  ASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPY--PHYQQAPGGPQFLLPYFPPEGPGPEA 156
           A S  P G P  P      P P   A  +PP   P   QAP  PQ       P  P P  
Sbjct: 196 APSSAPPGTPQLP-----TPGPTPSATAVPPQGSPTASQAPNQPQ------APTAPVPHT 244

Query: 157 LGFVGDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQG 216
              +  A PA   + P       P+P PPP P  + P   L     +P+ P  A   L G
Sbjct: 245 --HIQQA-PALHPQRP-------PSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHG 294

Query: 217 HLGHFPGPEPL-AFPVKELQGSGARPGVPLYPPGLSELKVAEVKEG-ALLGAGKAKA-PK 273
                PGP  L A P+ +       PG P  P GL      +  +G A LG   A A P 
Sbjct: 295 Q--GPPGPHSLQAGPLLQ------HPGPP-QPFGLP----PQASQGQAPLGTSPAAAYPH 341

Query: 274 TARALALPDKVLLEDAMKLFDCLPGASEPEGTLCEVPGPALPDSSGGNSADDIRSLCLPE 333
           T+  L      L          LP A      +   P   +P      +      L  P 
Sbjct: 342 TSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPS 401

Query: 334 EL-LSFDYSVPEILDTVSNVDYFFNFKALDEEQPPHPGPPATNTPAPILSGKRKASTAKK 392
              ++ +   P  L  +S         +L    PP   PP    P  ++   +   ++  
Sbjct: 402 PFSMNANLPPPPALKPLS---------SLSTHHPPSAHPP----PLQLMPQSQPLPSSPA 448

Query: 393 GKPGRKARQ--PAGPASATPPG 412
             PG    Q  P  PAS  P G
Sbjct: 449 QPPGLTQSQNLPPPPASHPPTG 470



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 22/72 (30%), Positives = 30/72 (41%), Gaps = 10/72 (13%)

Query: 360 ALDEEQPPHPGPPATNTP----APILSGKRKASTAKKGKPGRKARQPAGPAS--ATP--- 410
           AL  ++PP P PP   +P     P+     + S     +P    + P GP S  A P   
Sbjct: 251 ALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQ 310

Query: 411 -PGPREDLGATP 421
            PGP +  G  P
Sbjct: 311 HPGPPQPFGLPP 322


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 109/391 (27%), Positives = 134/391 (34%), Gaps = 83/391 (21%)

Query: 32   PAPTCAEPPPAMGSLNLYHPPDPEKEVFPAPPAGFQMAPCGCFFDPRIYRIEWTTPDLGQ 91
            P P+    PP         P  P+    P P    Q AP      P+  R     P    
Sbjct: 766  PTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPA---LHPQ--RPPSPHPPPHP 820

Query: 92   SALYKLAASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQA------PGGPQ-FLL 144
            S    L   +G  AG PSAP       QP L   G PP PH  QA      PG PQ F L
Sbjct: 821  SPHPPLQPLTGS-AGQPSAPS----HAQPPLHGQG-PPGPHSLQAGPLLQHPGPPQPFGL 874

Query: 145  PYFPPEGPGPEALGFVGDAG-PAAFVELPL---------PPLEE--GPAPL------PP- 185
            P  P    G   LG    A  P   ++LP          PP E+   PAPL      PP 
Sbjct: 875  P--PQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPP 932

Query: 186  -------PPPKENKPPPVL---------ITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAF 229
                   P P+ +K PP L           LP  P L P   S L  H  H P   P   
Sbjct: 933  TTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKP--LSSLSTH--HPPSAHPP-- 986

Query: 230  PVKELQGSGARPGVPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDA 289
            P++ +  S   P  P  PPGL+        +   L    A  P T      P     +  
Sbjct: 987  PLQLMPQSQPLPSSPAQPPGLT--------QSQNLPPPPASHPPTGLHQVAPQPPFAQHP 1038

Query: 290  MKLFDCLPGASEPEGTLCEVPGPALPDSSGGNSAD-DIRSLCLPEELLSFDYSVPEILDT 348
                  +PG   P  T    P  + P +  G SA             ++   S P  L T
Sbjct: 1039 F-----VPGGPPPI-TPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCP--LPT 1090

Query: 349  VSNVDYFFNFKALDEEQPPHPGPPATNTPAP 379
            V         +ALD+ + P   PP   +P+P
Sbjct: 1091 VQ-----IKEEALDDAEEPESPPPPPRSPSP 1116



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 58/234 (24%), Positives = 81/234 (34%), Gaps = 68/234 (29%)

Query: 12   APQEGFSPQSLEGAEVLG---NQPAPTCAEPPPAMGSLNLYHPPD---------PEKEVF 59
            APQ    P  L G        N P P   +P   + SL+ +HPP          P+ +  
Sbjct: 941  APQAHKHPPHLSGPSPFSMNANLPPPPALKP---LSSLSTHHPPSAHPPPLQLMPQSQPL 997

Query: 60   PAPPAGFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQ 119
            P+ PA                      P L QS       +S  P G+      + + PQ
Sbjct: 998  PSSPA--------------------QPPGLTQSQNLPPPPASHPPTGL------HQVAPQ 1031

Query: 120  PYLKAPGLPPYPHYQQAPGGPQFLLP------YFPPEGPG----PEALGFVGDAG----- 164
            P        P+  +   PGGP  + P        PP GPG    P   G     G     
Sbjct: 1032 P--------PFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGG 1083

Query: 165  ---PAAFVELPLPPLEEGPAP-LPPPPPKENKPPPVLITLPAEPTLPPDAYSHL 214
               P   V++    L++   P  PPPPP+   P P ++  P+  +     Y HL
Sbjct: 1084 SSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHL 1137



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 84/322 (26%), Positives = 109/322 (33%), Gaps = 55/322 (17%)

Query: 99   ASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPY--PHYQQAPGGPQFLLPYFPPEGPGPEA 156
            A S  P G P  P      P P   A  +PP   P   QAP  PQ       P  P P  
Sbjct: 750  APSSAPPGTPQLP-----TPGPTPSATAVPPQGSPTASQAPNQPQ------APTAPVPHT 798

Query: 157  LGFVGDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQG 216
               +  A PA   + P       P+P PPP P  + P   L     +P+ P  A   L G
Sbjct: 799  --HIQQA-PALHPQRP-------PSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHG 848

Query: 217  HLGHFPGPEPL-AFPVKELQGSGARPGVPLYPPGLSELKVAEVKEG-ALLGAGKAKA-PK 273
                 PGP  L A P+ +       PG P  P GL      +  +G A LG   A A P 
Sbjct: 849  Q--GPPGPHSLQAGPLLQ------HPGPP-QPFGLP----PQASQGQAPLGTSPAAAYPH 895

Query: 274  TARALALPDKVLLEDAMKLFDCLPGASEPEGTLCEVPGPALPDSSGGNSADDIRSLCLPE 333
            T+  L      L          LP A      +   P   +P      +      L  P 
Sbjct: 896  TSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPS 955

Query: 334  EL-LSFDYSVPEILDTVSNVDYFFNFKALDEEQPPHPGPPATNTPAPILSGKRKASTAKK 392
               ++ +   P  L  +S         +L    PP   PP    P  ++   +   ++  
Sbjct: 956  PFSMNANLPPPPALKPLS---------SLSTHHPPSAHPP----PLQLMPQSQPLPSSPA 1002

Query: 393  GKPGRKARQ--PAGPASATPPG 412
              PG    Q  P  PAS  P G
Sbjct: 1003 QPPGLTQSQNLPPPPASHPPTG 1024



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 22/72 (30%), Positives = 30/72 (41%), Gaps = 10/72 (13%)

Query: 360 ALDEEQPPHPGPPATNTP----APILSGKRKASTAKKGKPGRKARQPAGPAS--ATP--- 410
           AL  ++PP P PP   +P     P+     + S     +P    + P GP S  A P   
Sbjct: 805 ALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQ 864

Query: 411 -PGPREDLGATP 421
            PGP +  G  P
Sbjct: 865 HPGPPQPFGLPP 876


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 109/391 (27%), Positives = 134/391 (34%), Gaps = 83/391 (21%)

Query: 32   PAPTCAEPPPAMGSLNLYHPPDPEKEVFPAPPAGFQMAPCGCFFDPRIYRIEWTTPDLGQ 91
            P P+    PP         P  P+    P P    Q AP      P+  R     P    
Sbjct: 766  PTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPA---LHPQ--RPPSPHPPPHP 820

Query: 92   SALYKLAASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQA------PGGPQ-FLL 144
            S    L   +G  AG PSAP       QP L   G PP PH  QA      PG PQ F L
Sbjct: 821  SPHPPLQPLTGS-AGQPSAPS----HAQPPLHGQG-PPGPHSLQAGPLLQHPGPPQPFGL 874

Query: 145  PYFPPEGPGPEALGFVGDAG-PAAFVELPL---------PPLEE--GPAPL------PP- 185
            P  P    G   LG    A  P   ++LP          PP E+   PAPL      PP 
Sbjct: 875  P--PQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPP 932

Query: 186  -------PPPKENKPPPVL---------ITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAF 229
                   P P+ +K PP L           LP  P L P   S L  H  H P   P   
Sbjct: 933  TTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKP--LSSLSTH--HPPSAHPP-- 986

Query: 230  PVKELQGSGARPGVPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDA 289
            P++ +  S   P  P  PPGL+        +   L    A  P T      P     +  
Sbjct: 987  PLQLMPQSQPLPSSPAQPPGLT--------QSQNLPPPPASHPPTGLHQVAPQPPFAQHP 1038

Query: 290  MKLFDCLPGASEPEGTLCEVPGPALPDSSGGNSAD-DIRSLCLPEELLSFDYSVPEILDT 348
                  +PG   P  T    P  + P +  G SA             ++   S P  L T
Sbjct: 1039 F-----VPGGPPPI-TPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCP--LPT 1090

Query: 349  VSNVDYFFNFKALDEEQPPHPGPPATNTPAP 379
            V         +ALD+ + P   PP   +P+P
Sbjct: 1091 VQ-----IKEEALDDAEEPESPPPPPRSPSP 1116



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 58/234 (24%), Positives = 81/234 (34%), Gaps = 68/234 (29%)

Query: 12   APQEGFSPQSLEGAEVLG---NQPAPTCAEPPPAMGSLNLYHPPD---------PEKEVF 59
            APQ    P  L G        N P P   +P   + SL+ +HPP          P+ +  
Sbjct: 941  APQAHKHPPHLSGPSPFSMNANLPPPPALKP---LSSLSTHHPPSAHPPPLQLMPQSQPL 997

Query: 60   PAPPAGFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQ 119
            P+ PA                      P L QS       +S  P G+      + + PQ
Sbjct: 998  PSSPA--------------------QPPGLTQSQNLPPPPASHPPTGL------HQVAPQ 1031

Query: 120  PYLKAPGLPPYPHYQQAPGGPQFLLP------YFPPEGPG----PEALGFVGDAG----- 164
            P        P+  +   PGGP  + P        PP GPG    P   G     G     
Sbjct: 1032 P--------PFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGG 1083

Query: 165  ---PAAFVELPLPPLEEGPAP-LPPPPPKENKPPPVLITLPAEPTLPPDAYSHL 214
               P   V++    L++   P  PPPPP+   P P ++  P+  +     Y HL
Sbjct: 1084 SSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHL 1137



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 84/322 (26%), Positives = 109/322 (33%), Gaps = 55/322 (17%)

Query: 99   ASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPY--PHYQQAPGGPQFLLPYFPPEGPGPEA 156
            A S  P G P  P      P P   A  +PP   P   QAP  PQ       P  P P  
Sbjct: 750  APSSAPPGTPQLP-----TPGPTPSATAVPPQGSPTASQAPNQPQ------APTAPVPHT 798

Query: 157  LGFVGDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQG 216
               +  A PA   + P       P+P PPP P  + P   L     +P+ P  A   L G
Sbjct: 799  --HIQQA-PALHPQRP-------PSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHG 848

Query: 217  HLGHFPGPEPL-AFPVKELQGSGARPGVPLYPPGLSELKVAEVKEG-ALLGAGKAKA-PK 273
                 PGP  L A P+ +       PG P  P GL      +  +G A LG   A A P 
Sbjct: 849  Q--GPPGPHSLQAGPLLQ------HPGPP-QPFGLP----PQASQGQAPLGTSPAAAYPH 895

Query: 274  TARALALPDKVLLEDAMKLFDCLPGASEPEGTLCEVPGPALPDSSGGNSADDIRSLCLPE 333
            T+  L      L          LP A      +   P   +P      +      L  P 
Sbjct: 896  TSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPS 955

Query: 334  EL-LSFDYSVPEILDTVSNVDYFFNFKALDEEQPPHPGPPATNTPAPILSGKRKASTAKK 392
               ++ +   P  L  +S         +L    PP   PP    P  ++   +   ++  
Sbjct: 956  PFSMNANLPPPPALKPLS---------SLSTHHPPSAHPP----PLQLMPQSQPLPSSPA 1002

Query: 393  GKPGRKARQ--PAGPASATPPG 412
              PG    Q  P  PAS  P G
Sbjct: 1003 QPPGLTQSQNLPPPPASHPPTG 1024



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 22/72 (30%), Positives = 30/72 (41%), Gaps = 10/72 (13%)

Query: 360 ALDEEQPPHPGPPATNTP----APILSGKRKASTAKKGKPGRKARQPAGPAS--ATP--- 410
           AL  ++PP P PP   +P     P+     + S     +P    + P GP S  A P   
Sbjct: 805 ALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQ 864

Query: 411 -PGPREDLGATP 421
            PGP +  G  P
Sbjct: 865 HPGPPQPFGLPP 876


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 71/254 (27%), Positives = 83/254 (32%), Gaps = 41/254 (16%)

Query: 2   QHPKPFCAPAAPQEGFSPQSLEGAEVLGNQPAPTCAEPPPAMGSLNLYHPPDPEKEVFPA 61
           Q   P      PQ G SPQ   G +  G  P P   + PP  G      PP P K   P 
Sbjct: 25  QEESPSLIAGNPQ-GPSPQG--GNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP 81

Query: 62  PPAGFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPY 121
           P      +P      P+        P  G +         G P G P   G+    P P 
Sbjct: 82  PQGDKSRSPRSPPGKPQ------GPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPP 135

Query: 122 LKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPA 181
            K  G PP     ++P  P        P+GP P+  G     GP      P P   +GP 
Sbjct: 136 GKPQGPPPQGDKSRSPRSPP-----GKPQGPPPQ--GGNQPQGPP-----PPPGKPQGPP 183

Query: 182 PL-------PPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKEL 234
           P        PPPP K   PPP             D     Q   G   GP P      + 
Sbjct: 184 PQGGKKPQGPPPPGKPQGPPP-----------QGDKSRSSQSPPGKPQGPPPQG--GNQP 230

Query: 235 QGSGARPGVPLYPP 248
           QG    PG P  PP
Sbjct: 231 QGPPPPPGKPQGPP 244



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 69/257 (26%), Positives = 83/257 (32%), Gaps = 50/257 (19%)

Query: 6   PFCAPAAPQEGFSPQSLEGAEVLGNQPAPTCAEPPPAMGSLNLYHPPDPEKEVFPAPPAG 65
           P   P  PQ G  PQ   G +  G  P P   + PP  G      PP P K   P P   
Sbjct: 90  PRSPPGKPQ-GPPPQG--GNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGD 146

Query: 66  FQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYLKAP 125
              +P                            +  G P G P   G+   +PQ     P
Sbjct: 147 KSRSP---------------------------RSPPGKPQGPPPQGGN---QPQGPPPPP 176

Query: 126 GLP--PYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPL 183
           G P  P P   + P GP    P   P+GP P+         P    + P P     P   
Sbjct: 177 GKPQGPPPQGGKKPQGPP---PPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGP 233

Query: 184 PPPPPKENKPPPVLITLPAEPTLP-----PDAYSHLQGHLGHFPGPEPLAFPVKE---LQ 235
           PPPP K   PPP     P  P  P     P A    +      P  +P   P +E    Q
Sbjct: 234 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQ 293

Query: 236 G----SGARPGVPLYPP 248
           G    +G  P  P  PP
Sbjct: 294 GPPPPAGGNPQQPQAPP 310



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 59/208 (28%), Positives = 70/208 (33%), Gaps = 45/208 (21%)

Query: 6   PFCAPAAPQEGFSPQSLEGAEVLGNQPAPTCAEPPPAMGSLNLYHPPDPEKEVFPAPPAG 65
           P   P  PQ G  PQ   G +  G  P P   + PP  G      PP P K   P PP G
Sbjct: 151 PRSPPGKPQ-GPPPQG--GNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGP-PPQG 206

Query: 66  FQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYLKAP 125
            +                              + SS  P G P  P      PQ   +  
Sbjct: 207 DK------------------------------SRSSQSPPGKPQGP-----PPQGGNQPQ 231

Query: 126 GLPPYPHYQQAP---GG--PQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGP 180
           G PP P   Q P   GG  PQ   P   P+GP P   G    +  +   +   PP +EG 
Sbjct: 232 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP-PAQGGSKSQSARSPPGKPQGPPQQEGN 290

Query: 181 APLPPPPPKENKPPPVLITLPAEPTLPP 208
            P  PPPP    P         +P  PP
Sbjct: 291 NPQGPPPPAGGNPQQPQAPPAGQPQGPP 318



 Score = 32.3 bits (72), Expect = 0.83
 Identities = 39/146 (26%), Positives = 46/146 (31%), Gaps = 33/146 (22%)

Query: 9   APAAPQEGFSPQSLEGAEVLGNQPAPTCAEPPPAMGSLNLYHPPDPEKEVFPAPPAGFQM 68
           +P    +G  PQ   G +  G  P P   + PP  G      PP P K   P        
Sbjct: 214 SPPGKPQGPPPQG--GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP-------- 263

Query: 69  APCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYLKAPGLP 128
                             P  G S      +  G P G P   G+    P P   A G P
Sbjct: 264 ------------------PAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPP--PAGGNP 303

Query: 129 PYPHYQQAPGGPQFLLPYFPPEGPGP 154
             P   QAP   Q   P  PP+G  P
Sbjct: 304 QQP---QAPPAGQPQGPPRPPQGGRP 326



 Score = 29.3 bits (64), Expect = 7.0
 Identities = 16/58 (27%), Positives = 22/58 (37%)

Query: 364 EQPPHPGPPATNTPAPILSGKRKASTAKKGKPGRKARQPAGPASATPPGPREDLGATP 421
           ++P  P PP      P    K ++S +  GKP     Q        PP P +  G  P
Sbjct: 188 KKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 245


>gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]
          Length = 680

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 85/323 (26%), Positives = 99/323 (30%), Gaps = 69/323 (21%)

Query: 103 GPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGD 162
           GP G P   G   +       APG P  P  +  PG P    P  PP    P   G  G+
Sbjct: 250 GPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGE 309

Query: 163 AGPAAFVELPLPPLEEGPAPLPPPP----PKENKPPPVLITLPAEPTLPPDAYSHLQGHL 218
            GPA     P    E+GPA LP  P    P  N  P     +P    LP        G  
Sbjct: 310 RGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLP--------GPK 361

Query: 219 GHFPGPEPLAFP-VKELQGSGARPGVPLYP--PGLSELKVAEVKEGALLGAGKAKAPKTA 275
           G      P  +P  K  +GS    G P YP  PGL   K          G      PK  
Sbjct: 362 GETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPK----------GNPGLPGPKGD 411

Query: 276 RALALPDKVLLEDAMKLFDCLPGASEPEGTLCEVPGPALPDSSGGNSADDI---RSLCLP 332
             +  P               PG   P G       P     +G   A  I   R    P
Sbjct: 412 PGVGGP---------------PGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGP 456

Query: 333 EELLSFDYSVPEILDTVSNVDYFFNFKALDEEQPPHPGPPATNTPAPILSGKRKASTAKK 392
             +  F  S                     +  P  PGPP    PA I +      T   
Sbjct: 457 PGIPGFPGS---------------------KGDPGSPGPPG---PAGIATKGLNGPTGPP 492

Query: 393 GKPGRKAR--QPAGPASATPPGP 413
           G PG +    +P  P    PPGP
Sbjct: 493 GPPGPRGHSGEPGLPGPPGPPGP 515



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 80/315 (25%), Positives = 98/315 (31%), Gaps = 89/315 (28%)

Query: 103 GPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPYFP--PEGPGPEA-LGF 159
           GPAG    PG      +P   +PGL   P     PG      P  P  P  PG     G 
Sbjct: 66  GPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGP 125

Query: 160 VGDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLG 219
            GD GPA             P P  PP P    P P  I++P +P           G  G
Sbjct: 126 KGDVGPAGL-----------PGPRGPPGP-PGIPGPAGISVPGKP-----------GQQG 162

Query: 220 HFPGPEPLAFPVKELQGSGARPGVPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALA 279
               P P  FP     G    PGV    PG++  K  E+  GA    G+           
Sbjct: 163 PTGAPGPRGFP-----GEKGAPGV----PGMNGQK-GEMGYGAPGRPGERG--------- 203

Query: 280 LPDKVLLEDAMKLFDCLPGASEPEGTLCEVPGPALPDSSGGNSADDIRSLCLPEELLSFD 339
                           LPG   P        GP+ P   G    + +      +  +  D
Sbjct: 204 ----------------LPGPQGP-------TGPSGPPGVGKRGENGVPG----QPGIKGD 236

Query: 340 YSVPEILDTVSNVDYFFNFKALDEEQPPHP-GPPATNTPAPILSGKRKASTAKKGKPGRK 398
              P  +  +                PP P GPP    P  I       +  + G PG K
Sbjct: 237 RGFPGEMGPIG---------------PPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTK 281

Query: 399 ARQPAGPASATPPGP 413
              P  P  A PPGP
Sbjct: 282 G-LPGAPGIAGPPGP 295



 Score = 38.9 bits (89), Expect = 0.009
 Identities = 57/207 (27%), Positives = 70/207 (33%), Gaps = 29/207 (14%)

Query: 19  PQSLEGAEVLGNQPAPTCAEPPPAM-GSLNLYHPPDPEKEVFPAPPAGFQMAPCGCFFDP 77
           P  L G   L   P     + P  + GS  L   P P+ E  PA PAG+  A        
Sbjct: 327 PAGLPGKPGLTGPPGNMGPQGPKGIPGSHGL---PGPKGETGPAGPAGYPGA-------- 375

Query: 78  RIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSY----------LLEPQPYLKAPGL 127
              + E  +P       Y       GP G P  PG            L  P     A G+
Sbjct: 376 ---KGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGM 432

Query: 128 PPY---PHYQQAPGGPQFLLPYFPPEGPG-PEALGFVGDAGPAAFVELPLPPLEEGPAPL 183
           P +      + APG P    P  PP  PG P + G  G  GP     +    L     P 
Sbjct: 433 PGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPP 492

Query: 184 PPPPPKENKPPPVLITLPAEPTLPPDA 210
            PP P+ +   P L   P  P  P  A
Sbjct: 493 GPPGPRGHSGEPGLPGPPGPPGPPGQA 519



 Score = 33.5 bits (75), Expect = 0.37
 Identities = 43/152 (28%), Positives = 54/152 (35%), Gaps = 11/152 (7%)

Query: 98  AASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEAL 157
           A    GPAG+P  PG  L  P   +   G    P     PG      P  P   PG  A 
Sbjct: 321 AKGEQGPAGLPGKPG--LTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPG--AK 376

Query: 158 GFVGDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLP-PDAYSHLQG 216
           G  G  G       P  P  +GP   P  P  +  P      +   P LP P   +  +G
Sbjct: 377 GERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDP-----GVGGPPGLPGPVGPAGAKG 431

Query: 217 HLGHFPGPEPLAFP-VKELQGSGARPGVPLYP 247
             GH     P   P +   +G    PG+P +P
Sbjct: 432 MPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFP 463


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 100/432 (23%), Positives = 125/432 (28%), Gaps = 93/432 (21%)

Query: 5   KPFCAPAAPQEGFSPQSLEGAEVLGNQPAPTCAEPPPAMGSLNLYHPPDPEKEVFPAPPA 64
           KP   P+ P +   P    G +  G  P P   + PP  G      PP P K   P P  
Sbjct: 46  KPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 105

Query: 65  GFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYLKA 124
               +P      P+        P  G +         G P G P   G+    P P    
Sbjct: 106 DKSRSPRSPPGKPQ------GPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP---- 155

Query: 125 PGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPL- 183
           PG P  P  Q          P   P+GP P+  G     GP      P P   +GP P  
Sbjct: 156 PGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQ--GGNQPQGPP-----PPPGKPQGPPPQG 208

Query: 184 ------PPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGS 237
                 PPPP K   PPP           PP          G   GP P      + QG 
Sbjct: 209 GNKPQGPPPPGKPQGPPPQGDNKSQSARSPP----------GKPQGPPPQG--GNQPQGP 256

Query: 238 GARPGVPLYPPGLSELK-VAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCL 296
              PG P  PP     K       G   G       K+  + + P K             
Sbjct: 257 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQ------ 310

Query: 297 PGASEPEGTLCEVPGPALPDSSGGNSADDIRSLCLPEELLSFDYSVPEILDTVSNVDYFF 356
            G ++P+G       P  P   GGN                                   
Sbjct: 311 -GGNQPQGPPPPPGKPQGPPPQGGNK---------------------------------- 335

Query: 357 NFKALDEEQPPHPGPPATNTPAPILSGKRKASTAKKGKP-------GRKARQPAGPASAT 409
                  + PP PG P    P P    K +++ +  GKP       G   + P  PA   
Sbjct: 336 ------PQGPPPPGKP--QGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGN 387

Query: 410 PPGPREDLGATP 421
           P  P+      P
Sbjct: 388 PQQPQAPPAGQP 399



 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 85/341 (24%), Positives = 102/341 (29%), Gaps = 66/341 (19%)

Query: 98  AASSGG--PAGVPSAPGSYLLEPQPYLKAP-GLPPYPHYQQAP---GG--PQFLLPYFPP 149
           A   GG  P G PS PG     P      P G PP P   Q P   GG  PQ   P   P
Sbjct: 39  APPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP 98

Query: 150 EGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLP-- 207
           +GP P+         P    + P P     P   PPPP K   PPP     P  P  P  
Sbjct: 99  QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK 158

Query: 208 ---PDAYSHLQGHLGHFPGPEPLAFPVK---ELQGSGARPGVPLYPPGLSELK-VAEVKE 260
              P      +      P  +P   P +   + QG    PG P  PP     K       
Sbjct: 159 PQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP 218

Query: 261 GALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASEPEGTLCEVPGPALPDSSGG 320
           G   G       K+  A + P K              G ++P+G       P  P   GG
Sbjct: 219 GKPQGPPPQGDNKSQSARSPPGKPQGPPPQ-------GGNQPQGPPPPPGKPQGPPPQGG 271

Query: 321 NSADDIRSLCLPEELLSFDYSVPEILDTVSNVDYFFNFKALDEEQPPHPGPPATNTPAPI 380
           N                                          + PP PG P    P P 
Sbjct: 272 NK----------------------------------------PQGPPPPGKP--QGPPPQ 289

Query: 381 LSGKRKASTAKKGKPGRKARQPAGPASATPPGPREDLGATP 421
              K ++S +  GKP     Q        PP P +  G  P
Sbjct: 290 GGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 330



 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 55/205 (26%), Positives = 69/205 (33%), Gaps = 43/205 (20%)

Query: 9   APAAPQEGFSPQSLEGAEVLGNQPAPTCAEPPPAMGSLNLYHPPDPEKEVFPAPPAGFQM 68
           +P    +G  PQ   G +  G  P P   + PP  G      PP P K   P P  G + 
Sbjct: 237 SPPGKPQGPPPQG--GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSK- 293

Query: 69  APCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYLKAPGLP 128
                                        + SS  P G P  P      PQ   +  G P
Sbjct: 294 -----------------------------SRSSRSPPGKPQGP-----PPQGGNQPQGPP 319

Query: 129 PYPHYQQAP---GG--PQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPL 183
           P P   Q P   GG  PQ   P   P+GP P+  G    +  +   +   PP +EG  P 
Sbjct: 320 PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG-GSKSRSARSPPGKPQGPPQQEGNNPQ 378

Query: 184 PPPPPKENKPPPVLITLPAEPTLPP 208
            PPPP    P         +P  PP
Sbjct: 379 GPPPPAGGNPQQPQAPPAGQPQGPP 403


>gi|21389357 MAPK-interacting and spindle-stabilizing protein [Homo
           sapiens]
          Length = 245

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 69/251 (27%), Positives = 80/251 (31%), Gaps = 31/251 (12%)

Query: 4   PKPFCAPAAPQEGFSPQSLEGAEVLGNQPAPTCAEP--PPAMGSLNLYHPPDPEKEVFPA 61
           P    A +  + G  PQ   G+    N  AP+      PP+     +   P P       
Sbjct: 16  PAKTSAVSNTKPGQPPQGWPGSNPWNNPSAPSSVPSGLPPSATPSTVPFGPAPTGMYPSV 75

Query: 62  PPAGFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPY 121
           PP G    P   F            P  G S         GGP   P+ PG     P P 
Sbjct: 76  PPTGPPPGPPAPF------------PPSGPSC-----PPPGGPYPAPTVPGPGPTGPYPT 118

Query: 122 LKAPGLPPYPHYQQAPGGPQFLLPYFP--PEGPGPEALGFVGDAGPAAFVELPLPPLEEG 179
              P  P  P    AP  P    P  P      GP A G +G   P   +  P P    G
Sbjct: 119 PNMP-FPELPRPYGAPTDPAAAGPLGPWGSMSSGPWAPG-MGGQYPTPNMPYPSP----G 172

Query: 180 PAPLPPPPPKENKPPPV-LITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSG 238
           P P PPPP      PPV   T+P     PP  Y       G +P P     P    Q   
Sbjct: 173 PYPAPPPPQAPGAAPPVPWGTVPPGAWGPPAPY---PAPTGSYPTPGLYPTPSNPFQVPS 229

Query: 239 ARPGVPLYPPG 249
              G P  P G
Sbjct: 230 GPSGAPPMPGG 240


>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
          Length = 1682

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 59/217 (27%), Positives = 76/217 (35%), Gaps = 51/217 (23%)

Query: 87  PDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQP---YLKAPGL---------------- 127
           P LG  A     +   GP+  P  P   LL P P   +LK P                  
Sbjct: 448 PFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFG 507

Query: 128 ---------PPYPHYQQAPGGPQFLLP------YFPPEGPGPEALGFVGDAG-----PAA 167
                    PP PH +   G P           + PP  P P       ++G     PA 
Sbjct: 508 TEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAG 567

Query: 168 FVELPLPPL---EEGPAPLPPPPPKENKPPPVL-ITLPAEPTLPPDAYSHLQGHLGHFPG 223
            V  P PP       P P PP P +  + PP++ +TL   P  P   + +  G       
Sbjct: 568 PVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPES 627

Query: 224 PEP-LAFPVKELQGSGARPGVPL------YPPGLSEL 253
           P P ++FP     G G  PG PL       PPG+ EL
Sbjct: 628 PRPRVSFPKTPEVGPGPPPG-PLSKAPQPVPPGVGEL 663



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 34/105 (32%), Positives = 36/105 (34%), Gaps = 31/105 (29%)

Query: 171 LPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEP-----------TLPPDAYS------- 212
           LPLPP      PLPPPPP    PPP L  L   P           TL  DA+        
Sbjct: 244 LPLPP-----PPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSA 298

Query: 213 --------HLQGHLGHFPGPEPLAFPVKELQGSGARPGVPLYPPG 249
                   H   H   +P P   A P        A PG    PPG
Sbjct: 299 PPERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPG 343



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 100/417 (23%), Positives = 138/417 (33%), Gaps = 73/417 (17%)

Query: 51  PPDPEKEVFPAPPAG-FQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPS 109
           PP P +E F  PPA  F +        P        TP    S      ++SG  +  P+
Sbjct: 517 PPLPHREGFLGPPASRFSVGTQDSHTPPTP-----PTPTTSSSN-----SNSGSHSSSPA 566

Query: 110 APGSYLLEPQPYL--KAPGLPPYPHYQQAPGGPQFL-----LPYFPP------------- 149
            P S+   P PYL      LP  P   Q P  P  +     LP  PP             
Sbjct: 567 GPVSF--PPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRR 624

Query: 150 -EGPGPE-ALGFVGDAGPAAFVELPLPPLEEGPAPLPP--------PPPKENKPPPVL-- 197
            E P P  +     + GP      P  PL + P P+PP         P   + PP  L  
Sbjct: 625 PESPRPRVSFPKTPEVGPGP----PPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLED 680

Query: 198 -ITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGARPGVPLYPPGLSELKVA 256
               PAE  + PD  +++   L      E      ++   +G  P  PL  P  + L+  
Sbjct: 681 QFEEPAEFKILPDGLANIMKMLDESIRKE----EEQQQHEAGVAPQPPLKEP-FASLQSP 735

Query: 257 EVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASEPEGTLCEVPGPALPD 316
              + A      A A  T            E+  K     P A  P   L + P P+ P 
Sbjct: 736 FPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKK----PPPALPPPPPLAKFPPPSQPQ 791

Query: 317 ---SSGGNSADDIRSLCLPEELLSFDY-----SVPEILDTVSNVDYFFNFKALDEEQPP- 367
                  + A  ++SL    E   + Y     +V      +    Y     +     PP 
Sbjct: 792 PPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPT 851

Query: 368 HPGPPATNTPAPILSGKRKASTAKKGKP---GRKARQPAGPASATPPGPREDLGATP 421
              P A  +P P  S   + ST+  G P    R+A +   P   TP  P   L   P
Sbjct: 852 SAAPSAQGSPQPSASSSSQFSTS--GGPWARERRAGEEPVPGPMTPTQPPPPLSLPP 906



 Score = 32.3 bits (72), Expect = 0.83
 Identities = 74/304 (24%), Positives = 98/304 (32%), Gaps = 62/304 (20%)

Query: 2   QHPKPFCA-PAAPQEGFSPQSLEGAEVLGNQPAPTCAEPPPAMGSLNLYHPPDPEKEVFP 60
           + P+P  + P  P+ G  P    G      QP P      PA G      PP P ++ F 
Sbjct: 626 ESPRPRVSFPKTPEVGPGPPP--GPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFE 683

Query: 61  APPAGFQMAPCGC-----FFDPRIYRIEWTTPDLG----QSALYKLAASSGGPAGVPSAP 111
            P A F++ P G        D  I + E           Q  L +  AS   P    +AP
Sbjct: 684 EP-AEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAP 742

Query: 112 GSYL-----------------LEPQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGP 154
            +                    + +     P LPP P   + P   Q   P  PP  P P
Sbjct: 743 TTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPP--PPPPPSP 800

Query: 155 EAL-------------GFVGDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLP 201
            +L              + G     +    PLP  +  P     PP      PP      
Sbjct: 801 ASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPG----PPSGATALPPTSAAPS 856

Query: 202 AEPTLPPDAYSHLQGHLGHFP-------GPEPLAFPVKELQGSGARPGVPL-YPPGLSEL 253
           A+ +  P A S  Q      P       G EP+  P+   Q     P  PL  PP  SE 
Sbjct: 857 AQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQ-----PPPPLSLPPARSES 911

Query: 254 KVAE 257
           +V E
Sbjct: 912 EVLE 915


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 102/431 (23%), Positives = 127/431 (29%), Gaps = 83/431 (19%)

Query: 6    PFCAPAAPQEGFSPQSLEGAEVLGNQPAPTCAEPPPAMGSLNLYHPPDPEKEVFPAPPAG 65
            P   P +P+ G +  S +GA      P P  A PP   G      P  P  +  P PPA 
Sbjct: 966  PAATPPSPKGGPATPSPKGA------PTPPAATPPSPKGG-----PATPSPKGAPTPPAV 1014

Query: 66   FQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQ-----P 120
               +P G        +   T P     +     A++  P G P+ P + L  P+     P
Sbjct: 1015 TPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATP 1074

Query: 121  YLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGP 180
             LK    PP        GGP    P   P  P        G          P  P    P
Sbjct: 1075 SLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPP 1134

Query: 181  AP---LPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFP---GPEPLAFPVKEL 234
            +P   L  PPPK              PT P       +G L   P    P   A      
Sbjct: 1135 SPKGGLATPPPK------------GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1182

Query: 235  QGSGARP---GVPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALA-LPDKVLLEDAM 290
            +G  A P   G P  P            +G L       AP T  A    P   L   + 
Sbjct: 1183 KGGLATPSPKGAPTTPAA-----TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP 1237

Query: 291  KLFDCLPGASEPEGTLCEVPGPALPDSSGGNSADDIRSLCLPEELLSFDYSVPEILDTVS 350
            K     P A+ P        GPA P   G  +        L   L +             
Sbjct: 1238 KGAPTTPAATPPSPK----GGPATPPPKGAPTPPAATPPSLKGGLAT------------- 1280

Query: 351  NVDYFFNFKALDEEQPPHPGPPATNTPAPILSGKRKASTAKKGKPGRKARQPAGPASATP 410
                           PPH G P      P       A++  KG P         P +ATP
Sbjct: 1281 ---------------PPHKGAPNPAVVTPPSPKGGPATSPPKGAP--------TPPAATP 1317

Query: 411  PGPREDLGATP 421
            P P+   G  P
Sbjct: 1318 PSPKGSPGTPP 1328



 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 110/427 (25%), Positives = 140/427 (32%), Gaps = 83/427 (19%)

Query: 6    PFCAPAAPQEGFSPQSLEGAEVLGNQPAPTCAEPPPAMGSLNLYHPPDPEKEVFPAPPAG 65
            P   P +P+ G +  S +GA      P    A PP   G L       P  +  P  PA 
Sbjct: 1175 PAATPPSPKGGLATPSPKGA------PTTPAATPPSPKGGL-----ATPSPKGAPTTPAA 1223

Query: 66   FQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYLKAP 125
               +P G    P       T      S   K   ++  P G P+ P +      P LK  
Sbjct: 1224 TPPSPKGGLATPSPKGAPTTPAATPPSP--KGGPATPPPKGAPTPPAA----TPPSLKG- 1276

Query: 126  GLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPP 185
            GL   PH + AP  P  + P  P  GP        G   P A      PP  +G    PP
Sbjct: 1277 GLATPPH-KGAPN-PAVVTPPSPKGGPATSPPK--GAPTPPAAT----PPSPKGSPGTPP 1328

Query: 186  PPPKENKPPPVLITLPA---EPTLPPDAYSHLQGHL--GHFPGPEPLAFPVKELQGSGAR 240
            P   +  P P  +T P+    PTLP    S   G        GP P A       G    
Sbjct: 1329 P---KGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMT 1385

Query: 241  PGVPLYPPGLSELKVAEVKEGAL-LGAGKAKA-PKTARALALPDKVLLEDAMKLFDCL-- 296
            P  P   P +   K        + L   KA A P T    A P K  L         L  
Sbjct: 1386 PPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKK 1445

Query: 297  -PGASEPEGTLCEVPGPALPDSSGGNSADDIRSLCLPEELLSFDYSVPEILDTVSNVDYF 355
             P  S P+G      GPA P S G                   D ++P +          
Sbjct: 1446 APATSAPKG------GPATPSSKG-------------------DPTLPAVTPP------- 1473

Query: 356  FNFKALDEEQPPHPGPPATNTPAPILSGKRKASTAKKGKPGRKARQPAGP--ASATPPGP 413
                    ++PP P   AT++       K  A+ A  G P   A  P+ P    ATP   
Sbjct: 1474 ------SPKEPPAPKQVATSSSPK----KAPATPAPMGAPTLPAVIPSSPKEVPATPSSR 1523

Query: 414  REDLGAT 420
            R+ +  T
Sbjct: 1524 RDPIAPT 1530



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 94/416 (22%), Positives = 141/416 (33%), Gaps = 46/416 (11%)

Query: 9    APAAPQEGFSPQSLEGAEVLGNQPAPTCAEPPPAMGSLNLYHPPDPEKEVFPAPPAGFQM 68
            A +AP+ G +  S +G   L     P+  EPP       +     P+K      P G   
Sbjct: 1448 ATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPK---QVATSSSPKKAPATPAPMGAPT 1504

Query: 69   APCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYLKAPG-L 127
             P      P+       TP   +  +   A           AP   L+ P   + +P   
Sbjct: 1505 LPAVIPSSPKEVP---ATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKT 1561

Query: 128  PPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPPP 187
            P  P  ++AP  P         E   P A+      G  +  EL +PP    P+P   P 
Sbjct: 1562 PAIPTPKEAPATPS------SKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPT 1615

Query: 188  PKENKPP-----PVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGS--GAR 240
            P    PP     P        PT PP   S L+        P   A    ++  +   A 
Sbjct: 1616 PPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLK------DSPTSPASVTCKMGATVPQAS 1669

Query: 241  PGVPLY--PPGLSELKVAEVKEGA-LLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLP 297
             G+P    P  L E+ VA   E   ++ A   K P+T ++ A    +  + + K      
Sbjct: 1670 KGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAK-----N 1724

Query: 298  GASEPEGTLCEVPGPALP---DSS----GGNSADDIRSLCLPEELLSFDYSVPEILDTVS 350
            G+  P  T+   P P LP   DSS    G +++   +    P E  +   S P       
Sbjct: 1725 GSKGPLSTV--APAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKA---STPLTAAAFE 1779

Query: 351  NVDYFFNFKALDEEQPPHPGPPATNTPAPILSGKRKASTAKKGKPGRKARQPAGPA 406
             V       ++     P    P   +P P L  K++   +  G       +P  PA
Sbjct: 1780 KVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPA 1835



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 101/454 (22%), Positives = 144/454 (31%), Gaps = 58/454 (12%)

Query: 4    PKPFCAPAAPQEGFSPQSLEGAEVLGNQPAPTCAEPPPAMGSLNLYHPPDPEKEVFPAPP 63
            P P   P  P    +P S  G     ++  PT     P+        PP P++      P
Sbjct: 1341 PSPKGTPTLPAT--TPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSP 1398

Query: 64   AGFQMAPCGCFFDPR------IYRIEWTTPDLGQS--------ALYKLAASS---GGPAG 106
             G   +P      P+      + R    TP  G          +L K  A+S   GGPA 
Sbjct: 1399 KGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPA- 1457

Query: 107  VPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPA 166
             PS+ G   L P     +P  PP P        P+       P  P P     +    P+
Sbjct: 1458 TPSSKGDPTL-PAVTPPSPKEPPAPKQVATSSSPKKA-----PATPAPMGAPTLPAVIPS 1511

Query: 167  AFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPE- 225
            +  E+P  P      P+ P     +K  P  +  P E  +PP             P P+ 
Sbjct: 1512 SPKEVPATPSSRRD-PIAPTATLLSKKTPATLA-PKEALIPPAMTVPSPKKTPAIPTPKE 1569

Query: 226  -PLAFPVKELQGSGA----------RPGVPLYPPGLSELKVAEVKEGALLGAGKAKAPKT 274
             P     KE     A           P   L PP ++       KE     A    +P+ 
Sbjct: 1570 APATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTS---PSPKEAPTPPAVTPPSPEK 1626

Query: 275  ARALALPDKVLLEDAMKLFDCLPGASEPEGTLCEVPGPALPDSSGGNSADDIRSLCLPEE 334
              A   P        +         + P    C++ G  +P +S G  A    +      
Sbjct: 1627 GPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKM-GATVPQASKGLPAKKGPTALKEVL 1685

Query: 335  LLSFDYSVPEILDTVSNVDYFFNFKALDEEQPPHP-------GPPATNTPAPILSGKRKA 387
            +     S P I              A      P P       GP +T  PAP+L  ++ +
Sbjct: 1686 VAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDS 1745

Query: 388  STAKKGKPGRKARQPAGPASATPPGPREDLGATP 421
            S   KGK    +  P GP +     P E   +TP
Sbjct: 1746 SKTAKGKDA--SHSPKGPLA-----PPESKASTP 1772



 Score = 37.7 bits (86), Expect = 0.020
 Identities = 103/450 (22%), Positives = 140/450 (31%), Gaps = 77/450 (17%)

Query: 9    APAAPQEG-FSPQSLEGAEVLGNQPAPTCAEPPPAMGSLNLYHPPDPEKEVFPAPPAGFQ 67
            +P +P E  F P++    +   + PA T +  PP+         P P   V P  P G  
Sbjct: 826  SPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGA-----PTPSA-VTPLSPKGVT 879

Query: 68   MAPCGCFFDPRIYRIEW-----TTPDLGQSALYKLAASSG-------GPAGVPSAPGSYL 115
            + P      P +  + +      TP   Q+    + +SS         P G+P++P S  
Sbjct: 880  LPPKETP-TPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASP-SPK 937

Query: 116  LEPQPYLKAPGLP------PYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFV 169
              P P    P  P      P P +   P       P   P  P P+       A P +  
Sbjct: 938  GAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPK 997

Query: 170  ELPLPPLEEGPAPLPPP-PPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPE--P 226
              P  P  +G AP PP   P   K  P     P   + PP A           P P+  P
Sbjct: 998  GGPATPSPKG-APTPPAVTPPSPKGSPAATPFPKGASTPPAATP---------PSPKGSP 1047

Query: 227  LAFPVKELQGSGARPGVPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLL 286
             A P+   +G+   P   L P          +K      A    +PK   A   P    +
Sbjct: 1048 AATPLP--KGAPTTPAATL-PSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPM 1104

Query: 287  EDAMKLFDCLPGASEPEGTLCEVPGPALPDSSGGNSADDIRSLCLPEELLSFDYSVPEIL 346
              A            P+G L   P    P +           L  P          P+  
Sbjct: 1105 PPAAT-------PPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPP---------PKGA 1148

Query: 347  DTVSNVDYFFNFKALDEEQPPHPGPPATNTPAPILSGKRKASTAKKGKPGRKARQPAGP- 405
             T            L    PP  G P T    P       A+ + KG P   A  P  P 
Sbjct: 1149 PTTPAATPPSPKGGL--ATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1206

Query: 406  --------------ASATPPGPREDLGATP 421
                           +ATPP P+  L ATP
Sbjct: 1207 GGLATPSPKGAPTTPAATPPSPKGGL-ATP 1235



 Score = 35.8 bits (81), Expect = 0.075
 Identities = 88/374 (23%), Positives = 116/374 (31%), Gaps = 54/374 (14%)

Query: 83   EWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGP-- 140
            E  T D G SA    A+S G    +  +P    +   P  K P   P       P  P  
Sbjct: 769  ECPTEDSGASAT---ASSKGTLTYLADSPSPLGVSVSPQTKRP---PTKKGSAGPDTPIG 822

Query: 141  QFLLPYFPPEGPG-PE-ALGFVGDAGPAAFVELPLPPLEEG---PAPLPPPPPKENKPPP 195
                P  P E    PE +L F G     A    P PP  +G   P+ + P  PK    PP
Sbjct: 823  NLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPP 882

Query: 196  VLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGARPGVPLYPPGLSELKV 255
                 P+   LP              P     +   K+ + + A  G+P  P        
Sbjct: 883  KETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASP-------- 934

Query: 256  AEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASEPEGTLCEVPGPALP 315
               K      A    +PK   A   P       A        G + P       P  A P
Sbjct: 935  -SPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATP 993

Query: 316  DS-SGGNSADDIRSLCLPEELLSFDYSVPEILDTVSNVDYFFNFKALDEEQPPHP-GPPA 373
             S  GG +    +    P  +     + P    + +   +           PP P G PA
Sbjct: 994  PSPKGGPATPSPKGAPTPPAV-----TPPSPKGSPAATPFPKGASTPPAATPPSPKGSPA 1048

Query: 374  TN--------TPAPILSGKR--KASTAKKGKPGRKARQP----AGPAS-----------A 408
                      TPA  L   +   A+ + KG P   A  P     GPA+           A
Sbjct: 1049 ATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAA 1108

Query: 409  TPPGPREDLGATPH 422
            TPP P+  L   PH
Sbjct: 1109 TPPSPKGGLATPPH 1122



 Score = 34.3 bits (77), Expect = 0.22
 Identities = 39/153 (25%), Positives = 56/153 (36%), Gaps = 32/153 (20%)

Query: 148 PPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPA-----------PLPPPPPKENKPPPV 196
           PP   GP  +  +    PAA V  P+ P E               PLP P   +N P  V
Sbjct: 465 PPMSSGP--ISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSV 522

Query: 197 LITLPAEPTLPPDAYSHLQG------HLGHFPGPEPLAFPVKE--------LQGSGARPG 242
           L+  P +  L     S L+G        G     +P   P+ +         Q + + P 
Sbjct: 523 LVKFPTQKDLQTVPAS-LEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPE 581

Query: 243 VPLYPPGLSELKVAEVKEGALLGAGKAKAPKTA 275
           +PL P    E  +A+   G  L  GK  +  T+
Sbjct: 582 IPLSP----EATLAKKSLGEPLPIGKPASSMTS 610


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 58/207 (28%), Positives = 79/207 (38%), Gaps = 18/207 (8%)

Query: 10  PAAPQEGFSPQS-LEGAEVLGNQPAPTCAEPPPAMGSLNLYHPPDPEKEVFPAPPAGFQM 68
           P  P    + +S   G EV   +PAP+    PP  G               P+P A  + 
Sbjct: 169 PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRP 228

Query: 69  APCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPA--GVPSAPGSYLLEPQPY----L 122
           +  G    P        +  L  SA    + +  GP+  G P AP ++  +P+P     L
Sbjct: 229 SAGGGLQRP-------ASRSLSSSATPLSSPARSGPSARGTPRAP-AHPSQPKPKGLQAL 280

Query: 123 KAPGLPPYPHYQQAPG-GPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPA 181
           + P + P P    AP  GP    P   P   G +A         A  +   LPP      
Sbjct: 281 RPPQVTP-PRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLAT 339

Query: 182 PLPPPPPKENKPPPVLITLPAEPTLPP 208
           PLP  PP  + PP  L TLP+ P  PP
Sbjct: 340 PLPLAPPSPSAPPS-LQTLPSPPATPP 365



 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 107/450 (23%), Positives = 139/450 (30%), Gaps = 50/450 (11%)

Query: 4   PKPFCAPAAPQEGFSPQSLEGAEVLGNQPAPTCAEPP----PAMGSLNLYHPPDPEKEVF 59
           P P  AP +P     P++         Q  P  A PP    P+     L  PP       
Sbjct: 566 PCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXL 625

Query: 60  PAPPAGFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQ 119
             PP     AP      P +  +   +P    +    L  +   P   P     +     
Sbjct: 626 ALPPL---QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 682

Query: 120 PYLKAPGLPPYPHYQQAPGGPQFLLP--YFPPEGPGPEALGFVGDAGPAAFVELPLPPLE 177
           P +     PP     QAP  P    P    PP  P    +       P A   L  PPL+
Sbjct: 683 PPVSPSATPP----SQAP--PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ 736

Query: 178 EGPAP--LPPPPPKENKPPPVLITLPAEP-TLPPDAYSHLQGHLGHFPGPEPLAFPVKEL 234
             P+P   PP  P    PP V   L A P  +PP   + L   +     P P A P    
Sbjct: 737 VPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLP--MSPLAKPPPQAPPALAT 794

Query: 235 QGSGARPGVPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARA--LALPDKVLLEDAMKL 292
               A P  P   PG +    +     + L     +AP    A  L +P        ++ 
Sbjct: 795 PPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 854

Query: 293 FDCLP------GASEPEGTLCEVPGPALPDSSGGNS--------ADDIRSLCLPEELLSF 338
               P        S P  TL   PGP  P S   +S             +   PEEL  +
Sbjct: 855 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY 914

Query: 339 DYSVPE---ILDTVSNVDYFFNFKALDEEQPPHP----GPPATNTPAPILSGKRKASTAK 391
           D S PE         + +      A     P  P    G P    P P  +G   A    
Sbjct: 915 D-SGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGL- 972

Query: 392 KGKPGRKARQPAGPASATPPGPREDLGATP 421
                    +  GP SATP     D G +P
Sbjct: 973 -----CTIYETEGPESATPAPGALDPGPSP 997



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 64/255 (25%), Positives = 89/255 (34%), Gaps = 31/255 (12%)

Query: 18  SPQSLEGAEVLGNQPAPTCAEPPPAMGSLNLYHPPDPEKEVFPAPPAGFQMAPCGCFFDP 77
           SP+  + +    ++PA T  + PP    L+L  P  P  +   +P      +P       
Sbjct: 433 SPRQTQASLTSPSRPASTPPDSPPLQAPLSL--PASPPLQTSLSPAVSPLSSPLTIHPLQ 490

Query: 78  RIYRIEWTTPDLGQSALYKL---AASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPY---- 130
            +  +   +P    S+L        SS  P  + + P S    P   L +   PP     
Sbjct: 491 ALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTAS 550

Query: 131 -----PHYQQAPGGPQFLL--PYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAP- 182
                PH +  P      L  P  P   P PE    +    P A   L  PPL+  P+P 
Sbjct: 551 APLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPP 610

Query: 183 -----LPPP--------PPKENKP-PPVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLA 228
                 PPP        PP +  P PP    L    T  P A + L  HL   P   P +
Sbjct: 611 LSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS 670

Query: 229 FPVKELQGSGARPGV 243
            PV+      A P V
Sbjct: 671 PPVQAPFSPPASPPV 685



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 100/455 (21%), Positives = 142/455 (31%), Gaps = 90/455 (19%)

Query: 4   PKPFCAPAAPQEGFSPQSLEGAEVLGNQPAPTCAEPPPAMGSLNLYHPP----------- 52
           P P  A   P    SP +    + L + PA   ++ PP+M +  +  PP           
Sbjct: 333 PSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVP 392

Query: 53  ----DPEKEVFPAPPAGFQMAPCGCFFDPRI---YRIEWTTPDLGQSALYKLAASSGGPA 105
                P  +  P+P A   +        P +   +     +P   Q++L   +  +  P 
Sbjct: 393 HSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPP 452

Query: 106 GVPSAPGSYLLEPQPYLK---APGLPPY----------------PHYQQAPGGPQFLLPY 146
             P       L   P L+   +P + P                  H  QAP     + P 
Sbjct: 453 DSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPL 512

Query: 147 FPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTL 206
                  P +L       PA+   L  PPLE  P+  PPP    + P    +T P   T 
Sbjct: 513 ETQSSLAPPSL----QTPPAS---LTTPPLENLPSLAPPPLQTASAP----LTTPHLETP 561

Query: 207 PPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGARPGVPLYPPGLSELKVAEVKEGALLGA 266
           P  A   LQ        P PL  P  E   S A P  P  PP L+   +  +    L   
Sbjct: 562 PCPAPCPLQA------PPSPLTTPPPETPSSIATP-PPQAPPALASPPLQGLPSPPLSPL 614

Query: 267 GKAKAPKTARALALPDKVLLEDAMKLFDCLPGASEPEGTLCEVPGPALPDSSGGNSADDI 326
                P+    LALP               P AS P   L   P P  P++         
Sbjct: 615 A-TPPPQAPPXLALPPLQAPPS--------PPASPPLSPLA-TPSPQAPNA--------- 655

Query: 327 RSLCLPEELLSFDYSVPEILDTVSNVDYFFNFKALDEEQPPHPGPPATNTPAPILSGKRK 386
               L   LL   +S P      +               PP   P + +   P  +    
Sbjct: 656 ----LAVHLLQAPFSPPPSPPVQAPF------------SPPASPPVSPSATPPSQAPPSL 699

Query: 387 ASTAKKGKPGRKARQPAGPASATPPGPREDLGATP 421
           A+   +  P   A  P  P++  PP     L A P
Sbjct: 700 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 734



 Score = 35.4 bits (80), Expect = 0.098
 Identities = 75/307 (24%), Positives = 93/307 (30%), Gaps = 46/307 (14%)

Query: 4   PKPFCAPAAPQEGFSPQSLEGAEVLGNQPAPTCAEPPPAMGSLNLYHPPDPEKEVFPA-- 61
           PKP    A      +P   + A  LG   +   A P P+        PPD      PA  
Sbjct: 272 PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATL 331

Query: 62  PPAGFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPY 121
           PP+            P    +    P    SA   L      PA  PS     +  P P 
Sbjct: 332 PPS-----------PPLATPLPLAPP--SPSAPPSLQTLPSPPATPPSQAPPSMTTP-PM 377

Query: 122 LKAPGLPPYPHYQ----------QAPGGPQFLLPY----------------FPPEGPGPE 155
              P L   P  Q          QAP  P  L                   F    P   
Sbjct: 378 QAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQT 437

Query: 156 ALGFVGDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPP-DAYSHL 214
                  + PA+      PPL + P  LP  PP +    P +  L +  T+ P  A S L
Sbjct: 438 QASLTSPSRPAS-TPPDSPPL-QAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSL 495

Query: 215 QGHLGHFPGPEPLAFPVKELQGSGARPGVPLYPPGLSELKVAEVKEGALLGAGKAKAPKT 274
             H    P    L  P  E Q S A P +   P  L+   +  +   A      A AP T
Sbjct: 496 ASHSPQAP-LSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLT 554

Query: 275 ARALALP 281
              L  P
Sbjct: 555 TPHLETP 561


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 74/253 (29%), Positives = 88/253 (34%), Gaps = 53/253 (20%)

Query: 10   PAAPQEGFSPQS-LEGAEVLGNQPAPTCAEPPPAMGSLNLYHPPDPEKEVFPAPP---AG 65
            P  P  G  P   L GA +    P P    PPP         PP P   + P PP   AG
Sbjct: 1078 PPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPP---------PPLPGAGIPPPPPLPGAG 1128

Query: 66   FQMAP----CGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPY 121
                P     G    P + R+    P                    P  PG+ +  P P 
Sbjct: 1129 IPPPPPLPGAGIPPPPPLPRVGIPPP--------------------PPLPGAGIPPPPP- 1167

Query: 122  LKAPGLPPYPHYQQAPGGPQFLLPYFPPEG-PGPEALGFVGDAGPAAFVELPLPPLEEGP 180
            L   G+PP P     PG      P  P  G P P  L   G   P      PLP +   P
Sbjct: 1168 LPGAGIPPPP---PLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPP-----PLPGMGIPP 1219

Query: 181  APLPP-PPPKENKPPPVLITLPAEPTLPPDAYSHLQGH--LGHFPGPEP---LAFPVKEL 234
            AP PP PPP    PPP L+ +   P LP    S L      G  P P P       + + 
Sbjct: 1220 APAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGLFGLGMNQD 1279

Query: 235  QGSGARPGVPLYP 247
            +GS  +P  P  P
Sbjct: 1280 KGSRKQPIEPCRP 1292



 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 78/256 (30%), Positives = 91/256 (35%), Gaps = 56/256 (21%)

Query: 10   PAAPQEGFSPQS-LEGAEVLGNQPAPTCAEPPPAMGSLNLYHPPDPEKEVFPAPP---AG 65
            P  P  G  P   L GA +    P P    PPP         PP P   + P PP   AG
Sbjct: 968  PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP---------PPLPGAGIPPPPPLPGAG 1018

Query: 66   FQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYLKAP 125
                P                P  G      L  +   P   P  PG+ +  P P L   
Sbjct: 1019 IPPPP--------------PLPGAGIPPPPPLPGAGIPPP--PPLPGAGIPPPPP-LPGA 1061

Query: 126  GLPPYPHYQQAPGGPQFLLP--YFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPL 183
            G+PP P    A   P   LP    PP  P P A   +    P   V +P PP   G A +
Sbjct: 1062 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA--GIPPPPPLPGVGIPPPPPLPG-AGI 1118

Query: 184  PPPPPKEN---KPPPVL--ITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAF----PVKEL 234
            PPPPP       PPP L    +P  P LP          +G  P P PL      P   L
Sbjct: 1119 PPPPPLPGAGIPPPPPLPGAGIPPPPPLP---------RVG-IPPPPPLPGAGIPPPPPL 1168

Query: 235  QGSGARPGVPLYPPGL 250
             G+G  P  PL  PG+
Sbjct: 1169 PGAGIPPPPPL--PGV 1182



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 91/341 (26%), Positives = 118/341 (34%), Gaps = 77/341 (22%)

Query: 5    KPFCAPAA---PQEGF--------SPQSLEGAEVLGNQPAPTCAEPPPAMGSLNLYHPPD 53
            +P C P A   PQ  F        SP+ +   ++  +QP  + ++PPP    L       
Sbjct: 766  RPPCPPGAESGPQTKFCSEISLIVSPRRIS-VQLDSHQPTQSISQPPPPPSLLWSAGQGQ 824

Query: 54   PEKEVFPAPPAGFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVP----- 108
            P  +   +    FQ                 T+ +   S+ +K + +   P  +P     
Sbjct: 825  PGSQPPHSISTEFQ-----------------TSHEHSVSSAFKNSCNIPSPPPLPCTESS 867

Query: 109  -SAPGSYLLEPQPY----LKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPG-----PEALG 158
             S PG  ++ P P     +  P LP     Q  P     +LP  PP  PG     P  L 
Sbjct: 868  SSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPL- 926

Query: 159  FVGDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHL 218
                  P A + LPLPPL     P PPP P    PPP  +     P  PP     L G  
Sbjct: 927  ------PGAGI-LPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPP-----LPG-- 972

Query: 219  GHFPGPEPLAF----PVKELQGSGARPGVPLYPPGLSELKVAEVKEGALLGAGKAKAPKT 274
               P P PL      P   L G+G  P  PL   G+            L GAG    P  
Sbjct: 973  AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP-------PPPPLPGAGIPPPPPL 1025

Query: 275  ARALALPDKVLLEDAMKLFDCLPGASEPEGTLCEVPGPALP 315
              A   P   L    +     LPGA  P       P P LP
Sbjct: 1026 PGAGIPPPPPLPGAGIPPPPPLPGAGIP-------PPPPLP 1059



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 75/254 (29%), Positives = 86/254 (33%), Gaps = 61/254 (24%)

Query: 10   PAAPQEGFSPQS-LEGAEVLGNQPAPTCAEPPPAMGSLNLYHPPDPEKEVFPAPP---AG 65
            P  P  G  P   L GA +    P P    PPP         PP P   + P PP   AG
Sbjct: 1023 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP---------PPLPGAGIPPPPPLPGAG 1073

Query: 66   FQMAPC--GCFFDPRIYRIEWTTPDLGQSALYKLAASSG-GPAGVPSAPGSYLLEPQPYL 122
                P   G    P         P L  + +       G G    P  PG+ +  P P L
Sbjct: 1074 IPPPPPLPGAGIPP--------PPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPP-L 1124

Query: 123  KAPGLPPYPHYQQAPGGPQFLLPY--FPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGP 180
               G+PP P    A   P   LP    PP  P P A              +P PP   G 
Sbjct: 1125 PGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGA-------------GIPPPPPLPG- 1170

Query: 181  APLPPPPPKEN---KPPPVL--ITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQ 235
            A +PPPPP       PPP L  + +P  P LP              P P PL        
Sbjct: 1171 AGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPG----------AGIPPPPPLPG-----M 1215

Query: 236  GSGARPGVPLYPPG 249
            G    P  PL PPG
Sbjct: 1216 GIPPAPAPPLPPPG 1229



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 37/147 (25%), Positives = 47/147 (31%), Gaps = 33/147 (22%)

Query: 18  SPQSLEGAEVLGNQPAPTCAEP-----PPAMGSLNLYHPPD-----------PEKEVFPA 61
           SP + +    L + P    AEP     PP+ G L +   P            P    FP 
Sbjct: 266 SPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPF 325

Query: 62  PPAGFQMAPCGC----------------FFD-PRIYRIEWTTPDLGQSALYKLAASSGGP 104
           P AG      G                 F D PR    E   P++G+ A  +L       
Sbjct: 326 PEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEE 385

Query: 105 AGVPSAPGSYLLEPQPYLKAPGLPPYP 131
           A  P AP +  L   P        PYP
Sbjct: 386 AQGPDAPAAASLPGSPAPSQRCFKPYP 412



 Score = 30.0 bits (66), Expect = 4.1
 Identities = 40/128 (31%), Positives = 49/128 (38%), Gaps = 29/128 (22%)

Query: 97  LAASSGGPAGVPSAPGSYLLEPQPYLKAPGLPP-YPHYQQAPGGPQFLLPYFPPEGPGPE 155
           LAA    P   PS  G       P  +AP LP   P  + +P    F    FP  GPG E
Sbjct: 283 LAAEPREPQQPPSPGGL------PVSEAPSLPAAQPAAKDSPSSTAFP---FPEAGPGEE 333

Query: 156 ALGF-VGDAGPA-------AFVELP--------LPPL-EEGPAPLPPPPPKENKPP--PV 196
           A G  V  AG         AF + P         P + E+ P  L   P +E + P  P 
Sbjct: 334 AAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPA 393

Query: 197 LITLPAEP 204
             +LP  P
Sbjct: 394 AASLPGSP 401


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 74/277 (26%), Positives = 97/277 (35%), Gaps = 58/277 (20%)

Query: 8   CAPAAPQEGFSPQSLEGAEV-----------LGNQPAPTCAEPPPAMGSLNLYHPPDPEK 56
           C+P   +    PQSL                +G+ PAP C   PP++      H PDP  
Sbjct: 652 CSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPAC---PPSLQQ----HFPDPAM 704

Query: 57  EVFPAPPAGFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLL 116
              P  P      P G                 GQ A          P      P   +L
Sbjct: 705 SFAPVLPPPSTPMPTGP----------------GQPA----PPGQQPPPLAQPTPLPQVL 744

Query: 117 EPQPYLKA----PGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELP 172
            PQP +      P LPPY       G P  L P   P+ P  + L  V    P   V  P
Sbjct: 745 APQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAP-LQPLAQVPPQMPPIPVVPP 803

Query: 173 LPPLE--EGPAP---------LPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQG-HLGH 220
           + PL   +G  P         +PP PP +   P V++   A P  P      LQ   L H
Sbjct: 804 ITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPH 863

Query: 221 FPGPEPLAFPVKEL--QGSGARPGVPLYPPGLSELKV 255
            PG  PLA P + +        P + + PPG++ L +
Sbjct: 864 PPG-APLAMPCRTIVPNAPATIPLLAVAPPGVAALSI 899



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 91/334 (27%), Positives = 115/334 (34%), Gaps = 69/334 (20%)

Query: 4    PKPFCAPAAPQEGFSPQSLEGAEVLGNQPAPTC-AEPPPAMGSLNLYHPPD-----PEKE 57
            P     P  P + FSP     A +L +  AP   A P   + ++ L HPP      P + 
Sbjct: 821  PTATVPPVPPPQYFSP-----AVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRT 875

Query: 58   VFPAPPAGFQM---APCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSY 114
            + P  PA   +   AP G         I      L    +Y  A     P  VP +P   
Sbjct: 876  IVPNAPATIPLLAVAPPGV----AALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHT 931

Query: 115  LLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLP 174
            +   +     P LPP P        PQ +LP  P   P P                  LP
Sbjct: 932  VQNMRATPPQPALPPQPTLP-----PQPVLPPQPTLPPQPV-----------------LP 969

Query: 175  PLEEGPAPLPPPPPKENKPP-PVLITLPAEPTLPPDAYSHL------------QGHLGHF 221
            P    P P P  PP+   PP PVL   PA P  P     HL            Q  LGH 
Sbjct: 970  PQPTRP-PQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGH- 1027

Query: 222  PGPEPLAFPVKELQGSGARPGVPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALP 281
              P P A  V     +   P VP+ P  +    + EV    LL A     P+   +LA  
Sbjct: 1028 --PAPYAVDV-----AAQVPTVPVPPAAVLSPPLPEV----LLPAAPELLPQFPSSLATV 1076

Query: 282  DKVLLEDAMKLFDCLPGASEPEGTLCEVPGPALP 315
               +     +    LP A+ P   L   PG A P
Sbjct: 1077 SASVQSVPTQTATLLPPANPP---LPGGPGIASP 1107



 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 97/389 (24%), Positives = 140/389 (35%), Gaps = 49/389 (12%)

Query: 3    HPKPFCAPAAPQEGFSPQSLEGAEVLGNQPAPTCAEPPPAMGSLNLYHPPDPEKEVFPAP 62
            H  P+ APA+ Q G +P  L+  + +   P    A+ PP M  + +  P  P   +   P
Sbjct: 758  HLPPYLAPAS-QVG-APAQLKPLQ-MPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLP 814

Query: 63   PAGFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYL 122
            PA   +        P +   ++ +P +    L  LAA    P   P+ P   +  P P  
Sbjct: 815  PALPDLPTATV---PPVPPPQYFSPAV---ILPSLAAPL--PPASPALPLQAVKLPHP-- 864

Query: 123  KAPGLP-PYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPL----- 176
              PG P   P     P  P   +P      PG  AL        +A  +LP  P+     
Sbjct: 865  --PGAPLAMPCRTIVPNAPA-TIPLLAVAPPGVAALSI-----HSAVAQLPGQPVYPAAF 916

Query: 177  -EEGPAPLPPPPP---KENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFP--GPEPLAFP 230
             +  P  +PP P    +  +  P    LP +PTLPP      Q  L   P   P+P   P
Sbjct: 917  PQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPP 976

Query: 231  VKELQGSGARPGVPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAM 290
               L      P  P+ PP         V+   L    +   P+ A   A P   +L    
Sbjct: 977  QPVLPPQPMLPPQPVLPPQ----PALPVRPEPL----QPHLPEQAAPAATPGSQIL---- 1024

Query: 291  KLFDCLPGASEPEGTLCEVPGPALPDSSGGNSADDIRSLCLPEELLSFDYSVPEILDTVS 350
             L    P A +    +  VP P  P +       ++     PE L  F  S+  +  +V 
Sbjct: 1025 -LGHPAPYAVDVAAQVPTVPVP--PAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQ 1081

Query: 351  NVDYFFNFKALDEEQPPHPGPPATNTPAP 379
            +V        L    PP PG P   +P P
Sbjct: 1082 SVPTQ-TATLLPPANPPLPGGPGIASPCP 1109



 Score = 37.7 bits (86), Expect = 0.020
 Identities = 60/209 (28%), Positives = 72/209 (34%), Gaps = 44/209 (21%)

Query: 4    PKPFCAPAA---PQEGFSPQ-SLEGAEVLGNQPA--PTCAEPPPAMGSLNLYHPPDPEKE 57
            P+P   P     PQ    PQ +L    VL  QP   P    PP  M       PP P   
Sbjct: 940  PQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALP 999

Query: 58   VFPAPPAGF---QMAPCGCFFDPRIYRIEWTTPD----LGQSALYKLAASSGGPAGVPSA 110
            V P P       Q AP               TP     LG  A Y +  ++  P  VP  
Sbjct: 1000 VRPEPLQPHLPEQAAPAA-------------TPGSQILLGHPAPYAVDVAAQVPT-VPVP 1045

Query: 111  PGSYLLEPQPYLKAPG----LPPYPH--------YQQAPGGPQFLLPYFPPEGPGPEALG 158
            P + L  P P +  P     LP +P          Q  P     LLP   P  PG     
Sbjct: 1046 PAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGGP--- 1102

Query: 159  FVGDAGPAAFVELPLPPLEEGPAPLPPPP 187
              G A P   V+L + P++E  A    PP
Sbjct: 1103 --GIASPCPTVQLTVEPVQEEQASQDKPP 1129



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 59/247 (23%), Positives = 83/247 (33%), Gaps = 50/247 (20%)

Query: 2    QHPKPFC---APAAPQEGFSPQSLEGAEVLGNQPAPTCAEPPPAMGSLNLYHPPDPEKEV 58
            +HP P     +P  P     P++ + +    +Q +    E P  + S  L     P    
Sbjct: 1320 EHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSK--EQPSFLASQQLLSQAGPSNPP 1377

Query: 59   FPAPPAGFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEP 118
              APPA   +AP      P +  +         S + + A+ +   AG P  P     E 
Sbjct: 1378 -GAPPA--PLAPSS----PPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSEL 1430

Query: 119  QPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEE 178
            +         P     +AP   Q L+    P  P PEA      + P      PLPP   
Sbjct: 1431 ETS------QPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPRE----PLPP--- 1477

Query: 179  GPAPLPPPPPKENKPPPVL-------------ITL--------PAEPTLPPDAYSHLQGH 217
               P P P P    P P L             ++L        P  PT+PP   S L+  
Sbjct: 1478 ---PAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESD 1534

Query: 218  LGHFPGP 224
             G  P P
Sbjct: 1535 -GEGPPP 1540



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 52/192 (27%), Positives = 65/192 (33%), Gaps = 41/192 (21%)

Query: 157 LGFVGDAGPAAFVELPLPPLEEG---------------------------PAPLPPPPPK 189
           LG + DA P+    +  PP+ EG                           PAP  PP  +
Sbjct: 637 LGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQ 696

Query: 190 ENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPG--PEPLAFPVKELQGSGARPGVPLYP 247
           ++ P P +   P  P  PP             PG  P PLA P    Q    +P VPL P
Sbjct: 697 QHFPDPAMSFAPVLP--PPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQP 754

Query: 248 PGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASEPEGT-L 306
                  V       L  A +  AP   + L +P   L   A       P    P  T L
Sbjct: 755 -------VPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPL 807

Query: 307 CEVPG--PALPD 316
             + G  PALPD
Sbjct: 808 AGIDGLPPALPD 819


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 83/339 (24%), Positives = 111/339 (32%), Gaps = 104/339 (30%)

Query: 118  PQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPG--PEALGFVGDAGPAAF---VELP 172
            P P   A    P PH      G   L    PP  P   P  L       P+A    V L 
Sbjct: 765  PPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLL 824

Query: 173  LPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVK 232
             P   +G AP PPPPP    PPP        P +P    +HL+ H      P P   P +
Sbjct: 825  EPATRDG-APQPPPPPP---PPP--------PPMPLQLEAHLRSHGLEPAAPSPRLRPEE 872

Query: 233  ELQGSGARPGV-----PLYPPGLSELKV----AEVKEGALLGAGKAKAPKTARA------ 277
             L   GA   +     PL PP   +  V    +E K+ A  GA ++ +P+  +A      
Sbjct: 873  SLDPPGAMQELLGALEPL-PPAPGDTGVGPPNSEGKDPA--GAYRSPSPQGTKAPRFVPL 929

Query: 278  --LALPDKVLLEDAMKLFDCLPGASEPEGTLCEVPGPALPDSSGGNSADDIRSLCLPEEL 335
              +  PD +L ++    F                  P + +  GG +ADD      PE  
Sbjct: 930  TSICFPDSLLQDEERSFF------------------PTMEEMFGGGAADDYGKAGPPE-- 969

Query: 336  LSFDYSVPEILDTVSNVDYFFNFKALDEEQP-----PHPGPPATNTPAPILSGKRKASTA 390
                                      DE  P     P PGPPA +   P   G+   +  
Sbjct: 970  --------------------------DEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGP 1003

Query: 391  KKGKPGRKARQP----------------AGPASATPPGP 413
            +    G    +P                +GP  A PP P
Sbjct: 1004 ETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPP 1042



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 114/471 (24%), Positives = 155/471 (32%), Gaps = 92/471 (19%)

Query: 4   PKPFCAPAAPQEGFS---PQSLEGA-EVLGNQPAPTCAEPPPAMGSLNLYHPPD------ 53
           P+    P A  +GF     Q L  A    G  P P    PPP + +   Y P        
Sbjct: 448 PQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLY 507

Query: 54  -PEKEVFPAPPAGFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPG 112
             + E +P P A  Q  P               +P L  S  +  A S  G    PS+ G
Sbjct: 508 GVQGEPYPGPAAHSQGLPT-------------ASPSLSYSTGHSPALSGHGGGWGPSSLG 554

Query: 113 -------SYLLEPQPYLKAPGLPPYPHYQQAPGGPQFL------LPYFPPEGPGPEALGF 159
                  S+++ P     A G PP      APG  ++L       P+  P G G  A G 
Sbjct: 555 GGGEASPSHIIRPLQSPPATGRPPGVGSPGAPG--KYLSSVLASAPFLAPPGAGSYAAGA 612

Query: 160 VGDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLG 219
            G  G     EL   P          PP +  +    LI    +   PP   S   G +G
Sbjct: 613 GGYKGKGDGSELLAGP--------GGPPAERTEDEEFLIQHLLQAPSPPRT-SGADGLVG 663

Query: 220 HFPGPEPLAFPVKELQGSGARPGVPLYPPGLSE------------LKVAEVKEGAL---- 263
                +  A   K L GSG   G P  P  L++               A + EGA     
Sbjct: 664 E----DGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALE 719

Query: 264 LGAGKAKAPKTA--RALALPDKVLLEDAMKLFDCLPGASEPEGTLCEVPGPALPDS---- 317
           LG G+ K  K    R    P+ +    A  +     GA E    L + P P  P +    
Sbjct: 720 LGLGRLKEKKKGPERGGETPEGL----ATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQ 775

Query: 318 ---------SGGNSADDIRSLCLPEELLSFDYSVPEILDTVSNVDYFFNFKALDEEQP-P 367
                    +GG     +     P+ L S     P    + S V       A  +  P P
Sbjct: 776 PTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQP 835

Query: 368 HPGPPATNTPAPI-LSGKRKASTAKKGKPGRKARQPAGPASATPPGPREDL 417
            P PP    P P+ L    ++   +   P  + R      S  PPG  ++L
Sbjct: 836 PPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRP---EESLDPPGAMQEL 883



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 58/203 (28%), Positives = 68/203 (33%), Gaps = 31/203 (15%)

Query: 13   PQEGFSP----QSLEGA-EVLGNQPAPTCAEPPPAMGS--LNLYHPPDPEKEVFPAPPAG 65
            P+E   P    Q L GA E L   P  T   PP + G      Y  P P+    P     
Sbjct: 870  PEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPR---- 925

Query: 66   FQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYLKAP 125
            F      CF D  +   E +     +      AA   G AG P   G       P    P
Sbjct: 926  FVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGP---PP 982

Query: 126  GLPPYPHYQQAPGGPQFLLPYFP--PEGPGPEALGFVGDAG-----PAAFVELPLPPLEE 178
            G P Y  Y           PY P    G GPE  G   D       P+     PL  ++ 
Sbjct: 983  GPPAYDPYG----------PYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQS 1032

Query: 179  GPAPLPPPPPKENKPPPVLITLP 201
            GP    PPPP    PPP   + P
Sbjct: 1033 GPHQAAPPPPPPPPPPPAPASEP 1055



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 81/320 (25%), Positives = 97/320 (30%), Gaps = 56/320 (17%)

Query: 131  PHYQQAPGGPQFLLPYFPPEG-PGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPPPP- 188
            P     P GP    P  P    PGP  L  +  A      E PL  LEE P P PPP P 
Sbjct: 1413 PKDTSTPDGP----PLAPAAAVPGPPPLPGLPSANSNGTPEPPL--LEEKPPPTPPPAPT 1466

Query: 189  -KENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGARPGVPLYP 247
             +   PPP     PA P+ PP     L       P P PL  P        A P  P  P
Sbjct: 1467 PQPQPPPPPPPPQPALPSPPP-----LVAPTPSSPPPPPLPPPPPP-----AMPSPPPPP 1516

Query: 248  PGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASEPEGTLC 307
            P  +    A  +E A       + P T R L L  K          D   G S  EG   
Sbjct: 1517 PPAAAPLAAPPEEPAAPSPEDPELPDT-RPLHLAKKQETAAVCGETDEEAGESGGEGIFR 1575

Query: 308  E----------VPGPALPDSSGGNS------------------ADDIRSLCLPEELLS-- 337
            E          +P   L   +G                      D  R  C     L   
Sbjct: 1576 ERDEFVIRAEDIPSLKLALQTGREPPPIWRVQKALLQKFTPEIKDGQRQFCATSNYLGYF 1635

Query: 338  ------FDYSVPEILDTVSNVDYFFNFKALDEEQPPHPGPPATNTPAPILSGKRKASTAK 391
                  +     + L+ V+  DY          +PP P   +     P+ +G   A   K
Sbjct: 1636 GDAKNRYQRLYVKFLENVNKKDYVRVCARKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPK 1695

Query: 392  KGKPGRKARQPAGPASATPP 411
               P  K   P    S  PP
Sbjct: 1696 APAPPPKPETPEKTTSEKPP 1715



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 49/146 (33%), Positives = 56/146 (38%), Gaps = 30/146 (20%)

Query: 85   TTPDLGQSALYKLAASSGGPA--GVPSA-----PGSYLLEPQPYLKAPGLP-PYPHYQQA 136
            +TPD     L   AA  G P   G+PSA     P   LLE +P    P  P P P     
Sbjct: 1417 STPD--GPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPP 1474

Query: 137  PGGPQFLLPYFPP-EGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPP-------PP 188
            P  PQ  LP  PP   P P +        P   +  P PP    P P PPP       PP
Sbjct: 1475 PPPPQPALPSPPPLVAPTPSS-------PPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPP 1527

Query: 189  KENKPPPVLITLPAEPTLPPDAYSHL 214
            +E   P      P +P LP     HL
Sbjct: 1528 EEPAAPS-----PEDPELPDTRPLHL 1548



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 36/124 (29%), Positives = 44/124 (35%), Gaps = 8/124 (6%)

Query: 111 PGSYLLEPQPYLKAPGLPPYPHYQQAPG--GPQFLLPYFPPEGPG-PEALGFV-----GD 162
           P S+   P P   +  L   P    A G   P  +L   P + P  P +LGF      G 
Sbjct: 154 PASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGV 213

Query: 163 AGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFP 222
            GPA       PP   GP   PPPP        +L +  A       +   L    G  P
Sbjct: 214 LGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAP 273

Query: 223 GPEP 226
           GP P
Sbjct: 274 GPPP 277



 Score = 29.3 bits (64), Expect = 7.0
 Identities = 22/61 (36%), Positives = 23/61 (37%), Gaps = 3/61 (4%)

Query: 4    PKPFCAPAAPQEGF-SPQSLEGAEVLGNQPAPTCAEPPPAMGSLNLYHPPDPEKEVFPAP 62
            P+P   P  PQ    SP  L         P P    PPPAM S     PP P      AP
Sbjct: 1469 PQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPP--PPPPPAAAPLAAP 1526

Query: 63   P 63
            P
Sbjct: 1527 P 1527


>gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens]
          Length = 1712

 Score = 52.4 bits (124), Expect = 8e-07
 Identities = 62/181 (34%), Positives = 72/181 (39%), Gaps = 29/181 (16%)

Query: 102 GGPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEAL---- 157
           GGP G+P  PG     P     A GL   P +  A GGP    P   P   G E      
Sbjct: 683 GGPKGLPGLPG-----PPGPTGAKGLRGIPGFAGADGGPG---PRGLPGDAGREGFPGPP 734

Query: 158 GFVGDAGPAAFVELPLPPLEEGPAPLPPP--PPKENKPPPVLITLPAEPTLPPDAYSHLQ 215
           GF+G  G    V LP P    GP  LP P  PP E   P  +  L A+P    DA    Q
Sbjct: 735 GFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERGLPGEV--LGAQPGPRGDAGVPGQ 792

Query: 216 GHLGHFPGPE-PLAFPVKE----LQGSGARPGVP-------LY-PPGLSELKVAEVKEGA 262
             L   PG   P  F   +    + G   +PG+P       LY PPGL     A  +EG 
Sbjct: 793 PGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGP 852

Query: 263 L 263
           L
Sbjct: 853 L 853



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 47/154 (30%), Positives = 55/154 (35%), Gaps = 32/154 (20%)

Query: 103 GPAGVPSAPGSYLLEPQPYLKA--------PGLPPYPHYQQAPGGPQFLLPYFPPEGPGP 154
           G AG P  PG     P P L          PG    P  Q  PG P    P     G G 
Sbjct: 338 GEAGDPGPPGLPAYSPHPSLAKGARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGDGD 397

Query: 155 EALGFVGDAGPAAFVELP-LPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSH 213
           +  G  G+ GP  F+  P +P L  GP   P P  K   P P        P LP      
Sbjct: 398 QRRGLPGEMGPKGFIGDPGIPALYGGP---PGPDGKRGPPGP--------PGLPGP---- 442

Query: 214 LQGHLGHFPGPEPLAFPVKELQGSGARPGVPLYP 247
                   PGP+   F +K  +G    PG+P  P
Sbjct: 443 --------PGPDGFLFGLKGAKGRAGFPGLPGSP 468



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 93/358 (25%), Positives = 120/358 (33%), Gaps = 68/358 (18%)

Query: 101 SGGPAGVPSAPGSYLLEPQPYLKAPGLPPYPH--YQQAPGGPQFLLPYFPPEGPGPEALG 158
           S G  G P   G    + +PY     LP      Y+  PG P  +    PP  PG     
Sbjct: 152 SEGFTGPPGPQGPKGQKGEPY----ALPKEERDRYRGEPGEPGLVGFQGPPGRPG----- 202

Query: 159 FVGDAGPAAFVELPLPPLEEGP----------------------APLPPPPPKENKPPPV 196
            VG  GP      P PP   GP                       P P   P +   P  
Sbjct: 203 HVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKGEKGDVGQPGPNGIPSDTLHP-- 260

Query: 197 LITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGARPGVPLYPPGLSELKVA 256
            I  P   T  PD Y   +G  G  PG   ++  +K  +G    PG+  Y PGLS  K +
Sbjct: 261 -IIAPTGVTFHPDQYKGEKGSEGE-PGIRGIS--LKGEEGIMGFPGLRGY-PGLSGEKGS 315

Query: 257 EVKEGA--LLG----------AGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASEPEG 304
             ++G+  L G           G+A  P      A      L    +     PGA    G
Sbjct: 316 PGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYSPHPSLAKGARGDPGFPGAQGEPG 375

Query: 305 TLCEVPGPALPDSSGGNSADDIRSLCLPEEL----LSFDYSVPEILDTVSNVDYFFNFKA 360
           +  E   P LP   G +  D  +   LP E+       D  +P +       D     K 
Sbjct: 376 SQGEPGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPD----GKR 431

Query: 361 LDEEQPPHPGPPATNTPAPILSGKRKASTAKKGKPGRKARQPAGPASATPPGPREDLG 418
                P  PGPP    P   L G  K +  + G PG     P  P +  P G + D G
Sbjct: 432 GPPGPPGLPGPPG---PDGFLFG-LKGAKGRAGFPG----LPGSPGARGPKGWKGDAG 481



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 56/188 (29%), Positives = 66/188 (35%), Gaps = 29/188 (15%)

Query: 19  PQSLEGAEVLGNQPAPTCAEPPPAMGSLNLYHPPDPEKEVFPAPPAGFQMAPCGCFFDPR 78
           P    GA+ L   P    A+  P    L    P D  +E FP PP          F  PR
Sbjct: 694 PPGPTGAKGLRGIPGFAGADGGPGPRGL----PGDAGREGFPGPPG---------FIGPR 740

Query: 79  IYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYL-LEPQPYLKAPGLPPYPHYQQAP 137
             +     P    S          GP G    PG  L  +P P   A G+P  P  +  P
Sbjct: 741 GSKGAVGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQPGPRGDA-GVPGQPGLKGLP 799

Query: 138 G--GPQFL-----LPYFP-----PEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPP 185
           G  GP        +P  P     P  PGP   G  G  GP      P  P +EGP  LP 
Sbjct: 800 GDRGPPGFRGSQGMPGMPGLKGQPGLPGPS--GQPGLYGPPGLHGFPGAPGQEGPLGLPG 857

Query: 186 PPPKENKP 193
            P +E  P
Sbjct: 858 IPGREGLP 865



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 33/111 (29%), Positives = 39/111 (35%), Gaps = 11/111 (9%)

Query: 103  GPAGVPSAPGSYLLE-----PQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPG-PEA 156
            G  G P APG+         PQ     PG       +  PG P  + P  PP  PG   A
Sbjct: 1374 GDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGA 1433

Query: 157  LGFVGDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLP 207
             G  G  G      +P    +EGP     P  +E  P       P  P LP
Sbjct: 1434 PGKAGPQGRGGVSAVPGFRGDEGPIGHQGPIGQEGAP-----GRPGSPGLP 1479



 Score = 30.4 bits (67), Expect = 3.2
 Identities = 58/218 (26%), Positives = 66/218 (30%), Gaps = 45/218 (20%)

Query: 103 GPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGD 162
           G  G+P  PG  +  P      PG P YP      G P  +         GP  LG  G 
Sbjct: 584 GFPGLPGPPGDGIKGP------PGDPGYPGIPGTKGTPGEM---------GPPGLGLPGL 628

Query: 163 AGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFP 222
            G   F          G A LP PP     P P     P +     D    + G      
Sbjct: 629 KGQRGF---------PGDAGLPGPPGFLGPPGPA--GTPGQIDCDTDVKRAVGGDRQEAI 677

Query: 223 GPEPLAFPVKELQGSGARPGVPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPD 282
            P  +  P K L G    PG    P G   L+      GA  G G    P  A     P 
Sbjct: 678 QPGCIGGP-KGLPGLPGPPG----PTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPG 732

Query: 283 KVLLEDAMKLFDCLPGASEPEGTLCEVPGPALPDSSGG 320
                         PG   P G+   V  P  PD S G
Sbjct: 733 P-------------PGFIGPRGSKGAVGLPG-PDGSPG 756


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 82/331 (24%), Positives = 115/331 (34%), Gaps = 58/331 (17%)

Query: 104  PAGVPSAPGSYLLEPQPYLKAPG---LPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFV 160
            P GV     S     +P L   G   L P P  ++    P    P  P   P  +     
Sbjct: 1213 PVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARP----PLSPERAPEHD---LE 1265

Query: 161  GDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGH 220
             +  P   + LPL P    P P P PP   + PP    T  + P++PP+  +  + H  H
Sbjct: 1266 VEPEPPMMLPLPLQP----PLPPPRPPRPPSPPPEPETTDASHPSVPPEPLA--EDHPPH 1319

Query: 221  FPGPEPLAFPVKELQGSGARPGVPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALAL 280
             PG   L   + + Q +   P  P   P LS          + L     + P +  +   
Sbjct: 1320 TPG---LCGSLAKSQSTETVPATPGGEPPLS-------GGSSGLSLSSPQVPGSPFSYPA 1369

Query: 281  PDKVLLEDAM-----KLFDCLPGASEPEGTL----CEVPGPALPDSSGGNSADDIRSLCL 331
            P   L    +     + F   P  SEP G L    C +P     + SG  ++  +    L
Sbjct: 1370 PSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGL 1429

Query: 332  PEEL---LSFDYSVPEILDTVSNVDYFFNFKALDEEQPPHPGPPATNTPAPILSGKRKAS 388
            P  L   L    ++P +L                + + P P PP    PAP+ S      
Sbjct: 1430 PLPLPLPLPLPLALPAVLRA--------------QARAPTPLPPL--LPAPLAS----CP 1469

Query: 389  TAKKGKPGRKARQPAGPASATPPGPREDLGA 419
               K KPGR  R P    S   P  R   GA
Sbjct: 1470 PPMKRKPGRPRRSPPSMLSLDGPLVRPPAGA 1500



 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 108/421 (25%), Positives = 132/421 (31%), Gaps = 138/421 (32%)

Query: 34   PTCAEPPPAMGSLNLYHP---PDPEKEVFPAPPAGFQMAPCGCFFDPRIYRIEWTTPDLG 90
            P    PPP   + +  HP   P+P  E  P    G     CG     +       TP  G
Sbjct: 1288 PRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGL----CGSLAKSQSTETVPATPG-G 1342

Query: 91   QSALYKLAASSGGPAG-------VPSAPGSYLLEPQPYLKAPGLPPYPHYQ-------QA 136
            +  L      SGG +G       VP +P SY   P P L + GLP  P            
Sbjct: 1343 EPPL------SGGSSGLSLSSPQVPGSPFSYPA-PSPSLSSGGLPRTPGRDFSFTPTFSE 1395

Query: 137  PGGPQFLLPYFP------PEGPGPEALGFVGDAGPAAFVELPLP-PLE---------EGP 180
            P GP  LLP  P       E  GP A   + + G    + LPLP PL            P
Sbjct: 1396 PSGP-LLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAP 1454

Query: 181  APLPP---------PPPKENKP-------------------PPV-------LITLPAEPT 205
             PLPP         PPP + KP                   PP        L+ LP +P 
Sbjct: 1455 TPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQ 1514

Query: 206  LPPDAYSH------LQGHLGHFPGP-----------------EPLAFPVKELQGSGARPG 242
             P    +H      L       P P                 EP   P KEL        
Sbjct: 1515 TPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEA 1574

Query: 243  VPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASEP 302
            +P  P G  E+   E  E A       + PK                    D +P A  P
Sbjct: 1575 IPPGPRGRDEV-TEEYMELAKSRGPWRRPPKKRHE----------------DLVPPAGSP 1617

Query: 303  EGTLCEVPGPALPDSS-------------GGNSADDIRSLCLP-EELLSFDYSVPEILDT 348
            E      P P     S             GG   +DIR LC+  E LL  D  +  + DT
Sbjct: 1618 E---LSPPQPLFRPRSEFEEMTILYDIWNGGIDEEDIRFLCVTYERLLQQDNGMDWLNDT 1674

Query: 349  V 349
            +
Sbjct: 1675 L 1675



 Score = 48.9 bits (115), Expect = 9e-06
 Identities = 79/292 (27%), Positives = 99/292 (33%), Gaps = 53/292 (18%)

Query: 101 SGGPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPY------FPPEGPGP 154
           +GG +G P     +  +PQ        PP      APG      PY      FPP    P
Sbjct: 360 TGGSSGPP-----FKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEP 414

Query: 155 EALGFVGDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYS-H 213
            A    G      F   P PP      PLPP  P   + P    T P  P  PPD  S  
Sbjct: 415 TATAAFGARDSGEFRRAPAPP------PLPPAEPLAKEKPG---TPPGPP--PPDTNSME 463

Query: 214 LQGHLGHFPGPEPLAFP-VKELQGSGARPGVPLYP-PGLSELKVAEVKEGALLGAGKAKA 271
           L G       PEP   P    L+ S A P  P        E+ + E +   L      + 
Sbjct: 464 LGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLF----LRE 519

Query: 272 PKTARALALPDKVLLEDAMKLFDCLP-GASEPEGTLCEVPGPALPDSSGGNSADDIRSLC 330
           P +   L +    +   + +L    P G +   G     P  + P S+G    +DI    
Sbjct: 520 PDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTG---LEDISPTP 576

Query: 331 LPEELLSFDYSVPEILDTVSNVDYFFNFKALDEEQPPHPGPPATNTPAPILS 382
           LP      D    E LD             L    PP PGPP    PA +LS
Sbjct: 577 LP------DSDEDEELDL-----------GLGPRPPPEPGPP---DPAGLLS 608



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 36/95 (37%), Positives = 41/95 (43%), Gaps = 8/95 (8%)

Query: 171 LPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFP 230
           LPLPP   G  PLPPPPP    PPP     P  P LPP        H      P PL  P
Sbjct: 679 LPLPP-PPGFPPLPPPPP----PPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAP 733

Query: 231 VKELQGSGARPGVPLYPPGLSELKVAEVKEGALLG 265
              +      P +P +PPGL    V +V    +LG
Sbjct: 734 -PGVPPPPILPPLPPFPPGL--FPVMQVDMSHVLG 765



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 78/286 (27%), Positives = 104/286 (36%), Gaps = 60/286 (20%)

Query: 9   APAAPQEGFSPQSLEGAEVLGNQPAPTCAE---PPPAMGS-----LNLYHPPDPEKEVFP 60
           +P AP    S     G     ++P+ T  E   P P   S     L+L   P P  E  P
Sbjct: 541 SPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGP 600

Query: 61  APPAGFQMAPCGCFFDPRIYRIEWTTP-DLGQSALYKLAASSGGPAGVPSAPGSYLLEPQ 119
             PAG          D    R   +   D GQ +  +    S     +PSAP +    P+
Sbjct: 601 PDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDE--MPSAPITSADCPK 658

Query: 120 PYLKAPG---------LPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVE 170
           P +  PG         L P       PG P    P  PP  P P   GF         + 
Sbjct: 659 PMVVTPGAAAVAAPSVLAPTLPLPPPPGFP----PLPPPPPPPPPQPGFP--------MP 706

Query: 171 LPLPPLEEGPAP------LPPPP----PKENKPPPVLITLPAEPTLPPDAYSHLQGHLGH 220
            PLPP    P P      +PPPP    P    PPP+   LP  P  PP  +  +Q  + H
Sbjct: 707 PPLPPPPPPPPPAHPAVTVPPPPLPAPPGV-PPPPI---LPPLPPFPPGLFPVMQVDMSH 762

Query: 221 FPGPE----PLAFPVKE------LQGSGARPGVPLYPPGLSELKVA 256
             G +    P++F ++       + G GA P    YPP ++    A
Sbjct: 763 VLGGQWGGMPMSFQMQTQVLSRLMTGQGACP----YPPFMAAAAAA 804


>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
            sapiens]
          Length = 1636

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 71/254 (27%), Positives = 82/254 (32%), Gaps = 48/254 (18%)

Query: 32   PAPTCAEPPPAMGSLNLYHPPDPEKEVFPAP-------PAGFQMAPCGCFFDPRIYRIEW 84
            P P C   PP       Y  P   K+  PA        PAGF     G    P+ +    
Sbjct: 905  PPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGP--QPQPHPQPH 962

Query: 85   TTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQ---PYLKAPGL----PPYPHYQQAP 137
             +   G     +           P APG  LL PQ   PY   PG+    PP  H Q  P
Sbjct: 963  PSQAFGPQPPQQPLPLQHPHLFPPQAPG--LLPPQSPYPYAPQPGVLGQPPPPLHTQLYP 1020

Query: 138  GGPQFLLPY------FPPEGP-------------------GPEALGFVGDAGPAAFVELP 172
            G  Q  LP       FP  GP                   GP+A         +A    P
Sbjct: 1021 GPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTP 1080

Query: 173  LPPLEEGPAPLP-----PPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPL 227
             P L   PAP P     PP P   +PPP L    A   L   +     G      G +PL
Sbjct: 1081 SPHLVPSPAPSPGPGPVPPRPPAAEPPPCLRRGAAAADLLSSSPESQHGGTQSPGGGQPL 1140

Query: 228  AFPVKELQGSGARP 241
              P K     G RP
Sbjct: 1141 LQPTKVDAAEGRRP 1154



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 65/248 (26%), Positives = 83/248 (33%), Gaps = 29/248 (11%)

Query: 5   KPFCAPAAPQEGFSPQSLEGAEVLGNQPAPTCAEPPPAMGSLNLYHPPDPEKEVFPAPPA 64
           KP   P AP+    P+  E   V    P       PP M    +  P  P+  +  A P 
Sbjct: 715 KPPPRPTAPKP-LLPRREESEAVEAGDPPEELRSLPPDM----VAGPRLPDTFLGSATPL 769

Query: 65  GFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSG-GPAGVPSAPGSYLLEPQPYLK 123
            F  +P      P  + +    P    S   +L      GP  +P APG  L     Y  
Sbjct: 770 HFPPSPFPSSTGPGPHYLSGPLPPGTYSGPTQLIQPRAPGPHAMPVAPGPALYPAPAYTP 829

Query: 124 APGLPPY----------PHYQQAPGGPQFLLPYFPP-EGPGPEALGFVGDAGPAAFVELP 172
             GL P           P+    P  P   LP  PP +  GPE    V  A     V+  
Sbjct: 830 ELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQFSGPELAMAVRPA--TTTVDSI 887

Query: 173 LPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQG------HLGHFPGPEP 226
             P+    AP P P P    PPP     P +P   P  Y++  G         HF    P
Sbjct: 888 QAPIPSHTAPRPNPTPA--PPPPCFPVPPPQPL--PTPYTYPAGAKQPIPAQHHFSSGIP 943

Query: 227 LAFPVKEL 234
             FP   +
Sbjct: 944 AGFPAPRI 951


>gi|194353976 transcription factor AP-2 epsilon (activating enhancer
           binding protein 2 epsilon) [Homo sapiens]
          Length = 442

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 66/229 (28%), Positives = 87/229 (37%), Gaps = 38/229 (16%)

Query: 104 PAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPE-ALGFVGD 162
           P G+ +A G   L   P       PP  H   A    +F  PYFPP  P P    G   D
Sbjct: 12  PDGLGAAAGGARLSSLPQAAYGPAPPLCHTPAATAAAEFQPPYFPPPYPQPPLPYGQAPD 71

Query: 163 AGPAAFVELPLPPLEEGPAPLPPPPP------------KENKPPPVLITLPAEP--TLPP 208
           A  AAF  L   P   G APL  P P            + ++ PP L+  PA      P 
Sbjct: 72  AA-AAFPHLAGDPY-GGLAPLAQPQPPQAAWAAPRAAARAHEEPPGLLAPPARALGLDPR 129

Query: 209 DAYSHLQGHLGH--FPGPEPLAFPVKELQGSGARPGV----PLYPPGLSELKVAEVKEGA 262
             Y+     L H    G   LA     L G  A PG+     +  PG+S L  + +K   
Sbjct: 130 RDYATAVPRLLHGLADGAHGLADAPLGLPGLAAAPGLEDLQAMDEPGMSLLDQSVIK--- 186

Query: 263 LLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASEPEGTLCEVPG 311
                  K P  ++A +L    L +D++     + G + P    C VPG
Sbjct: 187 -------KVPIPSKASSLSALSLAKDSL-----VGGITNPGEVFCSVPG 223


>gi|4508017 zinc finger protein 207 isoform a [Homo sapiens]
          Length = 478

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 58/203 (28%), Positives = 75/203 (36%), Gaps = 26/203 (12%)

Query: 120 PYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPG--PEALGFVGDAGPAAFVELP---LP 174
           P +  PGLPP P     P G   L+P  PP  PG  P   G      P   +  P   +P
Sbjct: 140 PPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGGMMPPGPGIP 199

Query: 175 PLEEG-PAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPV-K 232
           PL  G P  +PPP P+   PP       A+    P   +         P P+P   PV K
Sbjct: 200 PLMPGMPPGMPPPVPRPGIPP----MTQAQAVSAPGILNRPPAPTATVPAPQP---PVTK 252

Query: 233 ELQGSGARPGVPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKL 292
            L  S  + G P     ++    A     +L  + KA  P TA+A A     +  D   L
Sbjct: 253 PLFPSAGQMGTP-----VTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPL 307

Query: 293 FDCLPGASEPEGTLCEVPGPALP 315
                  +    T  E P P  P
Sbjct: 308 -------NSTPATTTEPPKPTFP 323



 Score = 29.3 bits (64), Expect = 7.0
 Identities = 23/77 (29%), Positives = 31/77 (40%), Gaps = 16/77 (20%)

Query: 127 LPPYPHYQQAPGGPQFLLPYFPPEGP-GPEALGFVGDAGPAAFVELPLPPLEEGPAPLP- 184
           +PP P   Q  G    + P  PP G  G    G  G      ++   +PP  +GP  +P 
Sbjct: 406 MPPQPGIPQQQG----MRPPMPPHGQYGGHHQGMPG------YLPGAMPPYGQGPPMVPP 455

Query: 185 ----PPPPKENKPPPVL 197
               PP P     PPV+
Sbjct: 456 YQGGPPRPPMGMRPPVM 472


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 47/145 (32%), Positives = 55/145 (37%), Gaps = 10/145 (6%)

Query: 103 GPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPP--EGP-GPEALGF 159
           GP G P  PGS+  +     K    PP  H    PGG  F  P  PP   GP GP  LGF
Sbjct: 575 GPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGF 634

Query: 160 VGDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLG 219
            G  G      +P  P   GP  L     K  K   +   +       P  +    G  G
Sbjct: 635 PGPPGERGHPGVPGHPGVRGPDGL-----KGQKGDTISCNVTYPGRHGPPGFDGPPGPKG 689

Query: 220 HFPGPEPLAFPVKELQGSGARPGVP 244
            FPGP+  A  +    G   RPG P
Sbjct: 690 -FPGPQG-APGLSGSDGHKGRPGTP 712



 Score = 48.9 bits (115), Expect = 9e-06
 Identities = 59/196 (30%), Positives = 75/196 (38%), Gaps = 30/196 (15%)

Query: 89  LGQSALYKLAASSGGPA--GVPSAPGSYLLEPQPYLKAPGLPPYP-HYQQA----PGGPQ 141
           +G   L+ L    G P   G P  PG  +  P P    PG P +P  Y +     P GP 
Sbjct: 331 VGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPP 390

Query: 142 FLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEG-PAPLPPPPPKENKP-PPVLIT 199
            LL       PG    G +G  GP  F  LP  P E G P      P K  KP  P L  
Sbjct: 391 GLLGR-----PGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPG 445

Query: 200 LPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGAR------------PGVPLYP 247
            P    LP  +  +    +G+ PGP+ +   V    G G +            PG P+ P
Sbjct: 446 APGLQGLPGSSVIYCS--VGN-PGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPG-PMGP 501

Query: 248 PGLSELKVAEVKEGAL 263
           PG   L   +  +G L
Sbjct: 502 PGPPGLPGRQGSKGDL 517



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 71/252 (28%), Positives = 86/252 (34%), Gaps = 48/252 (19%)

Query: 10   PAAPQEGFSPQSLEGAEVLGNQPAPTCAEPPPAMGSLNLYHP-----PDPEKEVFPAPPA 64
            P +P  G SP    G +     P P  +  PP         P     P P  +  P  P 
Sbjct: 1215 PGSP--GISPPGPRGKK---GPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPD 1269

Query: 65   GFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYLKA 124
            G + AP                P L  S    L     G  G+P  PG            
Sbjct: 1270 GPRGAP--------------GPPGLPGSV--DLLRGEPGDCGLPGPPGP----------- 1302

Query: 125  PGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLP 184
            PG P  P Y+  PG         P   PGP+  G  G  GP     LP PP  +GP  LP
Sbjct: 1303 PGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQ--GPHGFPGPPGEKGLPGPPGRKGPTGLP 1360

Query: 185  -----PPPPKENKPPPVLITLPAEPTL-PPDAYSHLQGHLGHFPGPEPLAFP-VKELQGS 237
                 P PP +    P +  LP  P +  P+    L G  G   GP     P +   +G 
Sbjct: 1361 GPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGP-SGPGCKGEPGLDGRRGV 1419

Query: 238  GARPGVPLYPPG 249
               PG P  PPG
Sbjct: 1420 DGVPGSP-GPPG 1430



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 37/108 (34%), Positives = 40/108 (37%), Gaps = 16/108 (14%)

Query: 103 GPAGVPSAPGSYLLEPQPYLKA-PGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEAL---- 157
           G  GVP  PG       P +   PGLP YP    APGG        PP   G + L    
Sbjct: 816 GFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLP 875

Query: 158 ---------GFVGDAGPAAFVELPLPPLEEGPAPLP--PPPPKENKPP 194
                    G  G  GP     LP PP  +GP  LP  P  P E   P
Sbjct: 876 GRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKP 923



 Score = 30.0 bits (66), Expect = 4.1
 Identities = 48/178 (26%), Positives = 58/178 (32%), Gaps = 30/178 (16%)

Query: 101  SGGPAGVPSAPGSYLLEPQPYLKA----------PGLPPYPHYQQAPGGPQFLLPYFPPE 150
            S GP G P   G   L  QP              PG+P  P  +   G P     +    
Sbjct: 1125 SSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKG 1184

Query: 151  GPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLP---PPPPKENK-----------PPPV 196
              G +    + D GP   V +P    E G    P   PP P+  K           P P 
Sbjct: 1185 QKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPA 1244

Query: 197  LITLPAEPTLPPDAYSHLQGHLG-----HFPGPEPLAFPVKELQGSGARPGVPLYPPG 249
              T  A   +P       QG  G       PGP  L   V  L+G     G+P  PPG
Sbjct: 1245 GATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLP-GPPG 1301


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.139    0.439 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,256,688
Number of Sequences: 37866
Number of extensions: 2183595
Number of successful extensions: 22028
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 358
Number of HSP's successfully gapped in prelim test: 1112
Number of HSP's that attempted gapping in prelim test: 10394
Number of HSP's gapped (non-prelim): 7187
length of query: 422
length of database: 18,247,518
effective HSP length: 105
effective length of query: 317
effective length of database: 14,271,588
effective search space: 4524093396
effective search space used: 4524093396
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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