Search of human proteins with 196259774

Search of human proteins with 196259774

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|196259774 peroxisomal biogenesis factor 5 isoform d [Homo
sapiens]
         (639 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|196259776 peroxisomal biogenesis factor 5 isoform d [Homo sap...  1284   0.0  
gi|196259774 peroxisomal biogenesis factor 5 isoform d [Homo sap...  1284   0.0  
gi|196259770 peroxisomal biogenesis factor 5 isoform a [Homo sap...  1274   0.0  
gi|21361204 peroxisomal biogenesis factor 5 isoform b [Homo sapi...  1258   0.0  
gi|196259772 peroxisomal biogenesis factor 5 isoform c [Homo sap...  1194   0.0  
gi|7706671 peroxisomal biogenesis factor 5-like [Homo sapiens]        395   e-110
gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]       65   2e-10
gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]       65   2e-10
gi|83415184 transmembrane and tetratricopeptide repeat containin...    61   3e-09
gi|167466177 cell division cycle protein 27 isoform 1 [Homo sapi...    55   2e-07
gi|167466175 cell division cycle protein 27 isoform 2 [Homo sapi...    55   2e-07
gi|224809432 transmembrane and tetratricopeptide repeat containi...    49   2e-05
gi|238859655 tetratricopeptide repeat domain 31 [Homo sapiens]         48   2e-05
gi|42476022 tetratricopeptide repeat domain 27 [Homo sapiens]          47   7e-05
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]         45   3e-04
gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens]                     44   3e-04
gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens]           43   0.001
gi|118766328 transmembrane and tetratricopeptide repeat containi...    42   0.002
gi|118766330 transmembrane and tetratricopeptide repeat containi...    42   0.002
gi|118402596 cell division cycle protein 23 [Homo sapiens]             40   0.005
gi|6912398 general transcription factor IIIC, polypeptide 3, 102...    40   0.005
gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens]       40   0.007
gi|24308141 small glutamine-rich tetratricopeptide repeat (TPR)-...    39   0.011
gi|56181387 STIP1 homology and U-box containing protein 1 [Homo ...    39   0.015
gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo ...    39   0.019
gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo ...    39   0.019
gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Hom...    39   0.019
gi|157266273 RANBP2-like and GRIP domain containing 1 [Homo sapi...    39   0.019
gi|221307607 RANBP2-like and GRIP domain containing 3 [Homo sapi...    38   0.025
gi|211059431 RANBP2-like and GRIP domain containing 4 [Homo sapi...    38   0.025

>gi|196259776 peroxisomal biogenesis factor 5 isoform d [Homo
           sapiens]
          Length = 639

 Score = 1284 bits (3322), Expect = 0.0
 Identities = 639/639 (100%), Positives = 639/639 (100%)

Query: 1   MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEAASKPLGVASED 60
           MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEAASKPLGVASED
Sbjct: 1   MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEAASKPLGVASED 60

Query: 61  ELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQRAPGVADLALSENWAQ 120
           ELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQRAPGVADLALSENWAQ
Sbjct: 61  ELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQRAPGVADLALSENWAQ 120

Query: 121 EFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLEQSEEKLWLGEPEGTA 180
           EFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLEQSEEKLWLGEPEGTA
Sbjct: 121 EFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLEQSEEKLWLGEPEGTA 180

Query: 181 TDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSEFLKFVRQIGEGQVSLESGAGSGRAQA 240
           TDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSEFLKFVRQIGEGQVSLESGAGSGRAQA
Sbjct: 181 TDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSEFLKFVRQIGEGQVSLESGAGSGRAQA 240

Query: 241 EQWAAEFIQQQGTSDAWVDQFTRPVNTSALDMEFERAKSAIESDVDFWDKLQAELEEMAK 300
           EQWAAEFIQQQGTSDAWVDQFTRPVNTSALDMEFERAKSAIESDVDFWDKLQAELEEMAK
Sbjct: 241 EQWAAEFIQQQGTSDAWVDQFTRPVNTSALDMEFERAKSAIESDVDFWDKLQAELEEMAK 300

Query: 301 RDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEA 360
           RDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEA
Sbjct: 301 RDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEA 360

Query: 361 AVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQR 420
           AVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQR
Sbjct: 361 AVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQR 420

Query: 421 QACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVR 480
           QACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVR
Sbjct: 421 QACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVR 480

Query: 481 LDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE 540
           LDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE
Sbjct: 481 LDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE 540

Query: 541 AVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMS 600
           AVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMS
Sbjct: 541 AVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMS 600

Query: 601 ENIWSTLRLALSMLGQSDAYGAADARDLSTLLTMFGLPQ 639
           ENIWSTLRLALSMLGQSDAYGAADARDLSTLLTMFGLPQ
Sbjct: 601 ENIWSTLRLALSMLGQSDAYGAADARDLSTLLTMFGLPQ 639


>gi|196259774 peroxisomal biogenesis factor 5 isoform d [Homo
           sapiens]
          Length = 639

 Score = 1284 bits (3322), Expect = 0.0
 Identities = 639/639 (100%), Positives = 639/639 (100%)

Query: 1   MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEAASKPLGVASED 60
           MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEAASKPLGVASED
Sbjct: 1   MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEAASKPLGVASED 60

Query: 61  ELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQRAPGVADLALSENWAQ 120
           ELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQRAPGVADLALSENWAQ
Sbjct: 61  ELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQRAPGVADLALSENWAQ 120

Query: 121 EFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLEQSEEKLWLGEPEGTA 180
           EFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLEQSEEKLWLGEPEGTA
Sbjct: 121 EFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLEQSEEKLWLGEPEGTA 180

Query: 181 TDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSEFLKFVRQIGEGQVSLESGAGSGRAQA 240
           TDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSEFLKFVRQIGEGQVSLESGAGSGRAQA
Sbjct: 181 TDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSEFLKFVRQIGEGQVSLESGAGSGRAQA 240

Query: 241 EQWAAEFIQQQGTSDAWVDQFTRPVNTSALDMEFERAKSAIESDVDFWDKLQAELEEMAK 300
           EQWAAEFIQQQGTSDAWVDQFTRPVNTSALDMEFERAKSAIESDVDFWDKLQAELEEMAK
Sbjct: 241 EQWAAEFIQQQGTSDAWVDQFTRPVNTSALDMEFERAKSAIESDVDFWDKLQAELEEMAK 300

Query: 301 RDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEA 360
           RDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEA
Sbjct: 301 RDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEA 360

Query: 361 AVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQR 420
           AVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQR
Sbjct: 361 AVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQR 420

Query: 421 QACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVR 480
           QACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVR
Sbjct: 421 QACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVR 480

Query: 481 LDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE 540
           LDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE
Sbjct: 481 LDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE 540

Query: 541 AVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMS 600
           AVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMS
Sbjct: 541 AVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMS 600

Query: 601 ENIWSTLRLALSMLGQSDAYGAADARDLSTLLTMFGLPQ 639
           ENIWSTLRLALSMLGQSDAYGAADARDLSTLLTMFGLPQ
Sbjct: 601 ENIWSTLRLALSMLGQSDAYGAADARDLSTLLTMFGLPQ 639


>gi|196259770 peroxisomal biogenesis factor 5 isoform a [Homo
           sapiens]
          Length = 654

 Score = 1274 bits (3296), Expect = 0.0
 Identities = 639/654 (97%), Positives = 639/654 (97%), Gaps = 15/654 (2%)

Query: 1   MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEA----------- 49
           MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEA           
Sbjct: 1   MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEAVSVLEVESPGA 60

Query: 50  ----ASKPLGVASEDELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQR 105
               ASKPLGVASEDELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQR
Sbjct: 61  ASEAASKPLGVASEDELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQR 120

Query: 106 APGVADLALSENWAQEFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLE 165
           APGVADLALSENWAQEFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLE
Sbjct: 121 APGVADLALSENWAQEFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLE 180

Query: 166 QSEEKLWLGEPEGTATDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSEFLKFVRQIGEG 225
           QSEEKLWLGEPEGTATDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSEFLKFVRQIGEG
Sbjct: 181 QSEEKLWLGEPEGTATDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSEFLKFVRQIGEG 240

Query: 226 QVSLESGAGSGRAQAEQWAAEFIQQQGTSDAWVDQFTRPVNTSALDMEFERAKSAIESDV 285
           QVSLESGAGSGRAQAEQWAAEFIQQQGTSDAWVDQFTRPVNTSALDMEFERAKSAIESDV
Sbjct: 241 QVSLESGAGSGRAQAEQWAAEFIQQQGTSDAWVDQFTRPVNTSALDMEFERAKSAIESDV 300

Query: 286 DFWDKLQAELEEMAKRDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRR 345
           DFWDKLQAELEEMAKRDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRR
Sbjct: 301 DFWDKLQAELEEMAKRDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRR 360

Query: 346 LQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTA 405
           LQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTA
Sbjct: 361 LQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTA 420

Query: 406 LMALAVSFTNESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSD 465
           LMALAVSFTNESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSD
Sbjct: 421 LMALAVSFTNESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSD 480

Query: 466 SLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLW 525
           SLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLW
Sbjct: 481 SLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLW 540

Query: 526 NKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNM 585
           NKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNM
Sbjct: 541 NKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNM 600

Query: 586 QRKSRGPRGEGGAMSENIWSTLRLALSMLGQSDAYGAADARDLSTLLTMFGLPQ 639
           QRKSRGPRGEGGAMSENIWSTLRLALSMLGQSDAYGAADARDLSTLLTMFGLPQ
Sbjct: 601 QRKSRGPRGEGGAMSENIWSTLRLALSMLGQSDAYGAADARDLSTLLTMFGLPQ 654


>gi|21361204 peroxisomal biogenesis factor 5 isoform b [Homo
           sapiens]
          Length = 631

 Score = 1258 bits (3255), Expect = 0.0
 Identities = 631/639 (98%), Positives = 631/639 (98%), Gaps = 8/639 (1%)

Query: 1   MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEAASKPLGVASED 60
           MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEAASKPLGVASED
Sbjct: 1   MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEAASKPLGVASED 60

Query: 61  ELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQRAPGVADLALSENWAQ 120
           ELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQRAPGVADLALSENWAQ
Sbjct: 61  ELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQRAPGVADLALSENWAQ 120

Query: 121 EFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLEQSEEKLWLGEPEGTA 180
           EFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLEQSEEKLWLGEPEGTA
Sbjct: 121 EFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLEQSEEKLWLGEPEGTA 180

Query: 181 TDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSEFLKFVRQIGEGQVSLESGAGSGRAQA 240
           TDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSEFLKFVRQIGEGQVSLESGAGSGRAQA
Sbjct: 181 TDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSEFLKFVRQIGEGQVSLESGAGSGRAQA 240

Query: 241 EQWAAEFIQQQGTSDAWVDQFTRPVNTSALDMEFERAKSAIESDVDFWDKLQAELEEMAK 300
           EQWAAEFIQQQGTSDAWVDQFTRPVNTSALDMEFERAKSAIE        LQAELEEMAK
Sbjct: 241 EQWAAEFIQQQGTSDAWVDQFTRPVNTSALDMEFERAKSAIE--------LQAELEEMAK 292

Query: 301 RDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEA 360
           RDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEA
Sbjct: 293 RDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEA 352

Query: 361 AVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQR 420
           AVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQR
Sbjct: 353 AVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQR 412

Query: 421 QACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVR 480
           QACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVR
Sbjct: 413 QACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVR 472

Query: 481 LDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE 540
           LDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE
Sbjct: 473 LDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE 532

Query: 541 AVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMS 600
           AVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMS
Sbjct: 533 AVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMS 592

Query: 601 ENIWSTLRLALSMLGQSDAYGAADARDLSTLLTMFGLPQ 639
           ENIWSTLRLALSMLGQSDAYGAADARDLSTLLTMFGLPQ
Sbjct: 593 ENIWSTLRLALSMLGQSDAYGAADARDLSTLLTMFGLPQ 631


>gi|196259772 peroxisomal biogenesis factor 5 isoform c [Homo
           sapiens]
          Length = 602

 Score = 1194 bits (3089), Expect = 0.0
 Identities = 602/639 (94%), Positives = 602/639 (94%), Gaps = 37/639 (5%)

Query: 1   MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEAASKPLGVASED 60
           MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEAASKPLGVASED
Sbjct: 1   MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEAASKPLGVASED 60

Query: 61  ELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQRAPGVADLALSENWAQ 120
           ELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQRAPGVADLALSENWAQ
Sbjct: 61  ELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQRAPGVADLALSENWAQ 120

Query: 121 EFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLEQSEEKLWLGEPEGTA 180
           EFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLEQSEEKLWLGEPEGTA
Sbjct: 121 EFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLEQSEEKLWLGEPEGTA 180

Query: 181 TDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSEFLKFVRQIGEGQVSLESGAGSGRAQA 240
           TDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSE                          
Sbjct: 181 TDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSE-------------------------- 214

Query: 241 EQWAAEFIQQQGTSDAWVDQFTRPVNTSALDMEFERAKSAIESDVDFWDKLQAELEEMAK 300
                      GTSDAWVDQFTRPVNTSALDMEFERAKSAIESDVDFWDKLQAELEEMAK
Sbjct: 215 -----------GTSDAWVDQFTRPVNTSALDMEFERAKSAIESDVDFWDKLQAELEEMAK 263

Query: 301 RDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEA 360
           RDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEA
Sbjct: 264 RDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEA 323

Query: 361 AVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQR 420
           AVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQR
Sbjct: 324 AVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQR 383

Query: 421 QACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVR 480
           QACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVR
Sbjct: 384 QACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVR 443

Query: 481 LDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE 540
           LDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE
Sbjct: 444 LDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE 503

Query: 541 AVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMS 600
           AVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMS
Sbjct: 504 AVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMS 563

Query: 601 ENIWSTLRLALSMLGQSDAYGAADARDLSTLLTMFGLPQ 639
           ENIWSTLRLALSMLGQSDAYGAADARDLSTLLTMFGLPQ
Sbjct: 564 ENIWSTLRLALSMLGQSDAYGAADARDLSTLLTMFGLPQ 602


>gi|7706671 peroxisomal biogenesis factor 5-like [Homo sapiens]
          Length = 626

 Score =  395 bits (1016), Expect = e-110
 Identities = 208/374 (55%), Positives = 272/374 (72%), Gaps = 15/374 (4%)

Query: 269 ALDMEFERAKSAIESDVDFWDKLQAELEEMAKRDAEAHPWLSDYDD----LTSATYDKGY 324
           +L+ EFERAK+A+ESD +FWDK+QAE EEMA+R+     W+S+  +    +T +  +KGY
Sbjct: 261 SLEEEFERAKAAVESDTEFWDKMQAEWEEMARRN-----WISENQEAQNQVTISASEKGY 315

Query: 325 QFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQ 384
            F  ENP +D P  FEEGL+RL+EGDLP  +L  EAA+ QDP   EAWQ+LG TQAENE 
Sbjct: 316 YFHTENPFKDWPGAFEEGLKRLKEGDLPVTILFMEAAILQDPGDAEAWQFLGITQAENEN 375

Query: 385 ELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQACETLRDWLRYTPAYAHLVTPAE 444
           E  AI AL+RCLEL+P+N  ALMALAVS+TN   Q+ AC+ L++W++  P Y +LV   +
Sbjct: 376 EQAAIVALQRCLELQPNNLKALMALAVSYTNTGHQQDACDALKNWIKQNPKYKYLVKSKK 435

Query: 445 EGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEY 504
              G  GL  ++R+  S +  S+   VKEL+L A   +   IDPD+Q GLGVLF+LSGE+
Sbjct: 436 ---GSPGL--TRRMSKSPVDSSVLEGVKELYLEAAHQNGDMIDPDLQTGLGVLFHLSGEF 490

Query: 505 DKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGI 564
           ++A+D F AAL+VRP DY LWN+LGATLANG++SEEAV AY RALE+QPG+IRSRYNLGI
Sbjct: 491 NRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGI 550

Query: 565 SCINLGAHREAVEHFLEALNMQRKSRGPRG-EGGAMSENIWSTLRLALSMLGQSDAYGAA 623
           SCINLGA+REAV +FL AL++QRKSR  +     A+S NIW+ LR+ALS++ Q + + AA
Sbjct: 551 SCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPAISGNIWAALRIALSLMDQPELFQAA 610

Query: 624 DARDLSTLLTMFGL 637
           +  DL  LL  F L
Sbjct: 611 NLGDLDVLLRAFNL 624


>gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]
          Length = 1036

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 63/226 (27%), Positives = 89/226 (39%), Gaps = 17/226 (7%)

Query: 361 AVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQR 420
           A++Q+P   EA+  LG    E  Q   AI   R  L LKPD     + LA +        
Sbjct: 71  AIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDME 130

Query: 421 QACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVR 480
            A +     L+Y P    +          + LG   + LG L       E K  +L A+ 
Sbjct: 131 GAVQAYVSALQYNPDLYCV---------RSDLGNLLKALGRLE------EAKACYLKAIE 175

Query: 481 LDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE 540
             P          LG +FN  GE   A+  F  A+++ PN    +  LG  L      + 
Sbjct: 176 TQPNFAV--AWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDR 233

Query: 541 AVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQ 586
           AVAAY RAL L P +     NL       G    A++ +  A+ +Q
Sbjct: 234 AVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQ 279



 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 58/245 (23%), Positives = 102/245 (41%), Gaps = 31/245 (12%)

Query: 348 EGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALM 407
           +G++  A+  FE AV  DP  ++A+  LG    E      A++A  R L L P++     
Sbjct: 194 QGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHG 253

Query: 408 ALAVSFTNESLQRQACETLRDWLRYTP----AYAHLVTPAEEGAGGAGLGPSKRILGSLL 463
            LA  +  + L   A +T R  +   P    AY +L    +E    A             
Sbjct: 254 NLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVA------------- 300

Query: 464 SDSLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNL---SGEYDKAVDCFTAALSVRPN 520
                 E ++ +  A+RL PT  D      L  L N+    G  ++AV  +  AL V P 
Sbjct: 301 ------EAEDCYNTALRLCPTHAD-----SLNNLANIKREQGNIEEAVRLYRKALEVFPE 349

Query: 521 DYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFL 580
                + L + L    + +EA+  Y+ A+ + P +  +  N+G +   +   + A++ + 
Sbjct: 350 FAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYT 409

Query: 581 EALNM 585
            A+ +
Sbjct: 410 RAIQI 414



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 28/95 (29%), Positives = 43/95 (45%), Gaps = 6/95 (6%)

Query: 495 GVLFNLSGEY------DKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRA 548
           GVL  LS  +      D++    T A+   P     ++ LG       Q +EA+  YR A
Sbjct: 46  GVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHA 105

Query: 549 LELQPGYIRSRYNLGISCINLGAHREAVEHFLEAL 583
           L L+P +I    NL  + +  G    AV+ ++ AL
Sbjct: 106 LRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSAL 140


>gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]
          Length = 1046

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 63/226 (27%), Positives = 89/226 (39%), Gaps = 17/226 (7%)

Query: 361 AVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQR 420
           A++Q+P   EA+  LG    E  Q   AI   R  L LKPD     + LA +        
Sbjct: 81  AIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDME 140

Query: 421 QACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVR 480
            A +     L+Y P    +          + LG   + LG L       E K  +L A+ 
Sbjct: 141 GAVQAYVSALQYNPDLYCV---------RSDLGNLLKALGRLE------EAKACYLKAIE 185

Query: 481 LDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE 540
             P          LG +FN  GE   A+  F  A+++ PN    +  LG  L      + 
Sbjct: 186 TQPNFAV--AWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDR 243

Query: 541 AVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQ 586
           AVAAY RAL L P +     NL       G    A++ +  A+ +Q
Sbjct: 244 AVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQ 289



 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 58/245 (23%), Positives = 102/245 (41%), Gaps = 31/245 (12%)

Query: 348 EGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALM 407
           +G++  A+  FE AV  DP  ++A+  LG    E      A++A  R L L P++     
Sbjct: 204 QGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHG 263

Query: 408 ALAVSFTNESLQRQACETLRDWLRYTP----AYAHLVTPAEEGAGGAGLGPSKRILGSLL 463
            LA  +  + L   A +T R  +   P    AY +L    +E    A             
Sbjct: 264 NLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVA------------- 310

Query: 464 SDSLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNL---SGEYDKAVDCFTAALSVRPN 520
                 E ++ +  A+RL PT  D      L  L N+    G  ++AV  +  AL V P 
Sbjct: 311 ------EAEDCYNTALRLCPTHAD-----SLNNLANIKREQGNIEEAVRLYRKALEVFPE 359

Query: 521 DYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFL 580
                + L + L    + +EA+  Y+ A+ + P +  +  N+G +   +   + A++ + 
Sbjct: 360 FAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYT 419

Query: 581 EALNM 585
            A+ +
Sbjct: 420 RAIQI 424



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 28/95 (29%), Positives = 43/95 (45%), Gaps = 6/95 (6%)

Query: 495 GVLFNLSGEY------DKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRA 548
           GVL  LS  +      D++    T A+   P     ++ LG       Q +EA+  YR A
Sbjct: 56  GVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHA 115

Query: 549 LELQPGYIRSRYNLGISCINLGAHREAVEHFLEAL 583
           L L+P +I    NL  + +  G    AV+ ++ AL
Sbjct: 116 LRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSAL 150


>gi|83415184 transmembrane and tetratricopeptide repeat containing 1
           [Homo sapiens]
          Length = 774

 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 60/245 (24%), Positives = 107/245 (43%), Gaps = 25/245 (10%)

Query: 348 EGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALM 407
           +G    A+  +  A++  P+H  A   LGT   +  +   A    +R L+L P +  AL 
Sbjct: 388 QGRNKEAIYHYRTALKLYPRHASALNNLGTLTRDTAE---AKMYYQRALQLHPQHNRALF 444

Query: 408 ALAVSFTNESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSD-S 466
            L     ++  + +A   L+D ++Y P +A   +                 L SLL++  
Sbjct: 445 NLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSS----------------LASLLAEQE 488

Query: 467 LFLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWN 526
            F E +E++   ++  P S   D+    GV    +G  +KAV  +  A+ + P+ ++   
Sbjct: 489 RFKEAEEIYQTGIKNCPDS--SDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMV 546

Query: 527 KLGATLANGNQSEEAVAAYRRALEL-QPGYIRSRYNLGISCINLGAHREAVEHFLEALNM 585
            LG    +  ++  A   Y+RAL++     I S   LG    N G + EA++ + EA  +
Sbjct: 547 NLGRLYRSLGENSMAEEWYKRALQVAHKAEILS--PLGALYYNTGRYEEALQIYQEAAAL 604

Query: 586 QRKSR 590
           Q   R
Sbjct: 605 QPSQR 609



 Score = 38.5 bits (88), Expect = 0.019
 Identities = 48/221 (21%), Positives = 89/221 (40%), Gaps = 36/221 (16%)

Query: 354 AVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSF 413
           AV  ++ A++  P H  A   LG       +  +A    +R L++    +  L  L   +
Sbjct: 527 AVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAHKAEI-LSPLGALY 585

Query: 414 TNESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFL--EV 471
            N     +A +  ++                     A L PS+R L   L+  L +  + 
Sbjct: 586 YNTGRYEEALQIYQE--------------------AAALQPSQRELRLALAQVLAVMGQT 625

Query: 472 KELFLAAVRLDPTSIDPDVQCG-----LGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWN 526
           KE    A ++    +  +  C      L  +++    +DKA+D    AL ++P D  + +
Sbjct: 626 KE----AEKMTNHIVSEETGCLECYRLLSAIYSKQENHDKALDAIDKALQLKPKDPKVIS 681

Query: 527 KL----GATLANGNQSEEAVAAYRRALELQPGYIRSRYNLG 563
           +L    G  L   N  ++A  +YR A++L P   ++  N+G
Sbjct: 682 ELFFTKGNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMG 722



 Score = 34.7 bits (78), Expect = 0.28
 Identities = 22/83 (26%), Positives = 39/83 (46%)

Query: 321 DKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQA 380
           DK  Q + ++P       F +G +  ++  L  A   +  AVQ +P   +AW  +G  Q 
Sbjct: 667 DKALQLKPKDPKVISELFFTKGNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMGGIQH 726

Query: 381 ENEQELLAISALRRCLELKPDNQ 403
              + + A +   R L+L PD++
Sbjct: 727 IKGKYVSARAYYERALQLVPDSK 749


>gi|167466177 cell division cycle protein 27 isoform 1 [Homo
           sapiens]
          Length = 830

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 36/131 (27%), Positives = 64/131 (48%), Gaps = 3/131 (2%)

Query: 462 LLSDSLFLEVKELFLAAVRLDPTSID---PDVQCGLGVLFNLSGEYDKAVDCFTAALSVR 518
           + S +L+   K++ L+ +  D T +D   P+  C  G  F+L  E+D A+  F  A+ V 
Sbjct: 544 IYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVD 603

Query: 519 PNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEH 578
           PN    +  LG       + ++A+A +R A+ + P +  + Y LG+          A  H
Sbjct: 604 PNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMH 663

Query: 579 FLEALNMQRKS 589
           F +AL++  +S
Sbjct: 664 FQKALDINPQS 674



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 20/77 (25%), Positives = 36/77 (46%)

Query: 350 DLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMAL 409
           +L  A+  F  A++ +P+H  AW  LG    + E+  LA    ++ L++ P +   L  +
Sbjct: 622 ELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHI 681

Query: 410 AVSFTNESLQRQACETL 426
            V         +A +TL
Sbjct: 682 GVVQHALKKSEKALDTL 698



 Score = 30.4 bits (67), Expect = 5.2
 Identities = 48/249 (19%), Positives = 94/249 (37%), Gaps = 24/249 (9%)

Query: 356 LLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTN 415
           +L +     D    EAW   G   +   +  +AI   +R +++ P+   A   L   F  
Sbjct: 560 VLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVL 619

Query: 416 ESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKEL- 474
                +A    R+ +R  P + +           A  G     LG +        + E+ 
Sbjct: 620 TEELDKALACFRNAIRVNPRHYN-----------AWYG-----LGMIYYKQEKFSLAEMH 663

Query: 475 FLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLAN 534
           F  A+ ++P S    + C +GV+ +   + +KA+D    A+ + P + L      + L  
Sbjct: 664 FQKALDINPQS--SVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFA 721

Query: 535 GNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRG 594
             + + A+       ++ P      + +G     LG    A+ +F  A+++      P+G
Sbjct: 722 NEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLD-----PKG 776

Query: 595 EGGAMSENI 603
               + E I
Sbjct: 777 ANNQIKEAI 785


>gi|167466175 cell division cycle protein 27 isoform 2 [Homo
           sapiens]
          Length = 824

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 36/131 (27%), Positives = 64/131 (48%), Gaps = 3/131 (2%)

Query: 462 LLSDSLFLEVKELFLAAVRLDPTSID---PDVQCGLGVLFNLSGEYDKAVDCFTAALSVR 518
           + S +L+   K++ L+ +  D T +D   P+  C  G  F+L  E+D A+  F  A+ V 
Sbjct: 538 IYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVD 597

Query: 519 PNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEH 578
           PN    +  LG       + ++A+A +R A+ + P +  + Y LG+          A  H
Sbjct: 598 PNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMH 657

Query: 579 FLEALNMQRKS 589
           F +AL++  +S
Sbjct: 658 FQKALDINPQS 668



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 20/77 (25%), Positives = 36/77 (46%)

Query: 350 DLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMAL 409
           +L  A+  F  A++ +P+H  AW  LG    + E+  LA    ++ L++ P +   L  +
Sbjct: 616 ELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHI 675

Query: 410 AVSFTNESLQRQACETL 426
            V         +A +TL
Sbjct: 676 GVVQHALKKSEKALDTL 692



 Score = 30.4 bits (67), Expect = 5.2
 Identities = 48/249 (19%), Positives = 94/249 (37%), Gaps = 24/249 (9%)

Query: 356 LLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTN 415
           +L +     D    EAW   G   +   +  +AI   +R +++ P+   A   L   F  
Sbjct: 554 VLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVL 613

Query: 416 ESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKEL- 474
                +A    R+ +R  P + +           A  G     LG +        + E+ 
Sbjct: 614 TEELDKALACFRNAIRVNPRHYN-----------AWYG-----LGMIYYKQEKFSLAEMH 657

Query: 475 FLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLAN 534
           F  A+ ++P S    + C +GV+ +   + +KA+D    A+ + P + L      + L  
Sbjct: 658 FQKALDINPQS--SVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFA 715

Query: 535 GNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRG 594
             + + A+       ++ P      + +G     LG    A+ +F  A+++      P+G
Sbjct: 716 NEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLD-----PKG 770

Query: 595 EGGAMSENI 603
               + E I
Sbjct: 771 ANNQIKEAI 779


>gi|224809432 transmembrane and tetratricopeptide repeat containing
           3 [Homo sapiens]
          Length = 914

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 26/88 (29%), Positives = 46/88 (52%)

Query: 498 FNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIR 557
           F+ + +++     F +AL V  N+  LWN +G  L N    E A+  + +A  +QP  I 
Sbjct: 422 FHRNWDWESEYTLFMSALKVNKNNAKLWNNVGHALENEKNFERALKYFLQATHVQPDDIG 481

Query: 558 SRYNLGISCINLGAHREAVEHFLEALNM 585
           +  N+G +  NL   +EA E ++ A ++
Sbjct: 482 AHMNVGRTYKNLNRTKEAEESYMMAKSL 509



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 32/113 (28%), Positives = 52/113 (46%), Gaps = 1/113 (0%)

Query: 478 AVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQ 537
           A R+ P  ++  +     +  N S   ++A   +  A+S+RP+    +   G  L   N+
Sbjct: 520 AARIAPNHLNVYINLANLIRANES-RLEEADQLYRQAISMRPDFKQAYISRGELLLKMNK 578

Query: 538 SEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSR 590
             +A  AY +ALEL        YNL I  I L    EA+++F  AL +  K +
Sbjct: 579 PLKAKEAYLKALELDRNNADLWYNLAIVHIELKEPNEALKNFNRALELNPKHK 631



 Score = 36.2 bits (82), Expect = 0.095
 Identities = 46/221 (20%), Positives = 91/221 (41%), Gaps = 14/221 (6%)

Query: 350 DLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMAL 409
           D  +   LF +A++ +  + + W  +G      +    A+    +   ++PD+  A M +
Sbjct: 427 DWESEYTLFMSALKVNKNNAKLWNNVGHALENEKNFERALKYFLQATHVQPDDIGAHMNV 486

Query: 410 AVSFTNESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRI----LGSLL-- 463
             ++ N +  ++A E+        P     + P ++ A  A + P+       L +L+  
Sbjct: 487 GRTYKNLNRTKEAEESYMMAKSLMPQ----IIPGKKYA--ARIAPNHLNVYINLANLIRA 540

Query: 464 SDSLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYL 523
           ++S   E  +L+  A+ + P           G L     +  KA + +  AL +  N+  
Sbjct: 541 NESRLEEADQLYRQAISMRPDF--KQAYISRGELLLKMNKPLKAKEAYLKALELDRNNAD 598

Query: 524 LWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGI 564
           LW  L        +  EA+  + RALEL P +  + +N  I
Sbjct: 599 LWYNLAIVHIELKEPNEALKNFNRALELNPKHKLALFNSAI 639


>gi|238859655 tetratricopeptide repeat domain 31 [Homo sapiens]
          Length = 519

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 32/90 (35%), Positives = 44/90 (48%)

Query: 494 LGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQP 553
           LG  F  +G Y +AV  FT AL + P D+ L+           Q   A+A  + AL L+P
Sbjct: 311 LGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRP 370

Query: 554 GYIRSRYNLGISCINLGAHREAVEHFLEAL 583
           G+ R  + LG + + L   REA   F E L
Sbjct: 371 GWPRGLFRLGKALMGLQRFREAAAVFQETL 400


>gi|42476022 tetratricopeptide repeat domain 27 [Homo sapiens]
          Length = 843

 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 57/229 (24%), Positives = 89/229 (38%), Gaps = 25/229 (10%)

Query: 320 YDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQ 379
           YDK ++       R       + L  L+  +    V  FE +V+ +P  +  W  LG   
Sbjct: 515 YDKAWELSRYRSARAQRS---KALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAY 571

Query: 380 AENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQACETLRDWLRYTPAYAH- 438
              E    +  A +RC+ L+PDN  A   L+ S+     + +A  TL++ L+    Y H 
Sbjct: 572 LALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCN--YEHW 629

Query: 439 ------LVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVRLDPTSIDPDVQC 492
                 ++T  + G     +    R+L  L      ++V ++ + AV    T    DV  
Sbjct: 630 QIWENYILTSTDVGEFSEAIKAYHRLL-DLRDKYKDVQVLKILVRAVIDGMTDRSGDVAT 688

Query: 493 GL-GVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE 540
           GL G L  L G     V           ND  +W        NG QSE+
Sbjct: 689 GLKGKLQELFGRVTSRV----------TNDGEIWRLYAHVYGNG-QSEK 726



 Score = 37.4 bits (85), Expect = 0.043
 Identities = 21/81 (25%), Positives = 36/81 (44%)

Query: 503 EYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNL 562
           E+ + V+CF  ++ + P    +W  LG         + +  A++R + L+P    +  NL
Sbjct: 542 EFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNL 601

Query: 563 GISCINLGAHREAVEHFLEAL 583
             S I L    +A     EAL
Sbjct: 602 STSYIRLKQKVKAFRTLQEAL 622


>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
          Length = 2481

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 42/174 (24%), Positives = 78/174 (44%), Gaps = 14/174 (8%)

Query: 439 LVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLF 498
           L+  A E    AGLG + R +  L     + E ++L +A   L   + +      LG++ 
Sbjct: 427 LMEKAIEMRAYAGLGHAARCMQDLERAKQYHE-QQLGIAE-DLKDRAAEGRASSNLGIIH 484

Query: 499 NLSGEYDKAVDCFTAALSVRP--NDYLLWNKLGATLANGNQS----EEAVAAYRRALEL- 551
            + G+YD A+      L +    +DY    +    + N   +    ++AV  +R+ L++ 
Sbjct: 485 QMKGDYDTALKLHKTHLCIAQELSDYAAQGRAYGNMGNAYNALGMYDQAVKYHRQELQIS 544

Query: 552 -----QPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMS 600
                +     +  NL ++   LGAH  A++H+   LN+ R+ R  + E  A+S
Sbjct: 545 MEVNDRASQASTHGNLAVAYQALGAHDRALQHYQNHLNIARELRDIQSEARALS 598



 Score = 38.1 bits (87), Expect = 0.025
 Identities = 22/88 (25%), Positives = 43/88 (48%)

Query: 502 GEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYN 561
           G++  A+  +  AL+V P + +L++   A      Q ++A+    +A  L P + ++ + 
Sbjct: 72  GDFHTAIVLYNEALAVDPQNCILYSNRSAAYMKIQQYDKALDDAIKARLLNPKWPKAYFR 131

Query: 562 LGISCINLGAHREAVEHFLEALNMQRKS 589
            G++   LG H +A+  F   L    KS
Sbjct: 132 QGVALQYLGRHADALAAFASGLAQDPKS 159



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 28/118 (23%), Positives = 46/118 (38%), Gaps = 12/118 (10%)

Query: 486 IDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVR------PNDYLLWNKLGATLANGNQSE 539
           ++      LG  + +  +YDKA+   T  L V       P +      L A      +  
Sbjct: 752 LEASAYAALGTAYRMIQKYDKALGYHTQELEVYQELSDLPGECRAHGHLAAVYMALGKYT 811

Query: 540 EAVAAYRRALEL-----QPGYIRSRY-NLGISCINLGAHREAVEHFLEALNMQRKSRG 591
            A   Y   L+L      P      Y N+GI+ +N+    EA+ +F + L M ++  G
Sbjct: 812 MAFKCYEEQLDLGQKLKDPSLEAQVYGNMGITKMNMNVMEEAIGYFEQQLAMLQQLSG 869



 Score = 29.6 bits (65), Expect = 8.9
 Identities = 22/105 (20%), Positives = 46/105 (43%), Gaps = 7/105 (6%)

Query: 485  SIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAA 544
            +++ D  CGLG ++   GEYD A+      L +         + G    N   + E++  
Sbjct: 994  ALESDAACGLGGVYQQMGEYDTALQYHQLDLQIAEETNNPTCQ-GRAYGNLGLTYESLGT 1052

Query: 545  YRRALELQPGYIRSRYNLG------ISCINLGAHREAVEHFLEAL 583
            + RA+  Q  ++     +       +S  +LG    A++++ +A+
Sbjct: 1053 FERAVVYQEQHLSIAAQMNDLAAKTVSYSSLGRTHHALQNYSQAV 1097


>gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens]
          Length = 519

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 51/236 (21%), Positives = 88/236 (37%), Gaps = 20/236 (8%)

Query: 354 AVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSF 413
           A+ ++  A + + K  E    LG      +Q   A   L   L L   + T +M   +  
Sbjct: 120 AIEVYNEAAKLNQKDWEISHNLGVCYIYLKQFNKAQDQLHNALNLNRHDLTYIMLGKIHL 179

Query: 414 TNESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSL-LSDSLFLEVK 472
               L + A E  +  + ++P    L+T                 LG L L   ++ +  
Sbjct: 180 LEGDLDK-AIEVYKKAVEFSPENTELLTT----------------LGLLYLQLGIYQKAF 222

Query: 473 ELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATL 532
           E    A+  DPT+    +  G   +    G++D A+  +       P    LWN +G   
Sbjct: 223 EHLGNALTYDPTNYKAILAAGS--MMQTHGDFDVALTKYRVVACAVPESPPLWNNIGMCF 280

Query: 533 ANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRK 588
               +   A++  +RA  L P   +  YNLG+  + +  +  A      A+N Q K
Sbjct: 281 FGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYASAFHFLSAAINFQPK 336



 Score = 31.2 bits (69), Expect = 3.1
 Identities = 20/92 (21%), Positives = 39/92 (42%)

Query: 496 VLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGY 555
           ++F L G   ++++ F     + P       ++  +L    + + A+  Y  A +L    
Sbjct: 75  LIFRLEGNIQESLELFQTCAVLSPQSADNLKQVARSLFLLGKHKAAIEVYNEAAKLNQKD 134

Query: 556 IRSRYNLGISCINLGAHREAVEHFLEALNMQR 587
               +NLG+  I L    +A +    ALN+ R
Sbjct: 135 WEISHNLGVCYIYLKQFNKAQDQLHNALNLNR 166


>gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens]
          Length = 1564

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 73/314 (23%), Positives = 116/314 (36%), Gaps = 39/314 (12%)

Query: 283 SDVDFWDKLQAELEEMAKRDAEAHPWLSDYDDLTSATYDKGYQFEE-----ENPLRDHPQ 337
           SD D  ++    L++++  DA+  P L     L S  Y     F+E     E+ L  +P 
Sbjct: 364 SDYDSSEEAIRTLDQIS--DADNIPGLLV---LKSLAYRNKGSFDEAAKIMEDLLSSYPD 418

Query: 338 PFE----EGLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALR 393
             E    E L    + D   A   F+ A+++D +  E    LG T     +E        
Sbjct: 419 LAEVHALEALIHFTKKDYLQAEKCFQRALEKDTEVAEYHYQLGLTYWFMGEETRKDKTKA 478

Query: 394 RCLELKPDNQTALMALAVSFTNESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLG 453
               LK       M     +     +    +  R    Y  A+    T AE GA    L 
Sbjct: 479 LTHFLKAARLDTYMGKVFCYLGHYYRDVVGDKNRARGCYRKAFELDDTDAESGAAAVDL- 537

Query: 454 PSKRILGSLLSDSLFLEVKELFLAAVRLDPTSIDPDVQCGL--------GVLFNLSGEYD 505
                       S+ LE  E+ LA +    T++      G         G+ +  +G++ 
Sbjct: 538 ------------SVELEDMEMALAIL----TTVTQKASAGTAKWAWLRRGLYYLKAGQHS 581

Query: 506 KAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGIS 565
           +AV    AAL   P D+  W  LG    +      A+ ++ +A EL P  I S + +   
Sbjct: 582 QAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALKSFTKASELNPESIYSVFKVAAI 641

Query: 566 CINLGAHREAVEHF 579
              LG ++EAV  +
Sbjct: 642 QQILGKYKEAVAQY 655



 Score = 36.2 bits (82), Expect = 0.095
 Identities = 18/52 (34%), Positives = 28/52 (53%)

Query: 359 EAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALA 410
           +  ++Q+  +  AW ++G   AE EQ   A SA ++  EL+PD   A   LA
Sbjct: 30  KTVLKQEKNNYNAWVFIGVAAAELEQPDQAQSAYKKAAELEPDQLLAWQGLA 81



 Score = 35.4 bits (80), Expect = 0.16
 Identities = 17/51 (33%), Positives = 27/51 (52%)

Query: 503 EYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQP 553
           EY +A+      L    N+Y  W  +G   A   Q ++A +AY++A EL+P
Sbjct: 21  EYKEALKHCKTVLKQEKNNYNAWVFIGVAAAELEQPDQAQSAYKKAAELEP 71



 Score = 35.0 bits (79), Expect = 0.21
 Identities = 29/107 (27%), Positives = 42/107 (39%), Gaps = 5/107 (4%)

Query: 450 AGLGPSKRILGSLLSDSLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVD 509
           A  G +   L  LL  SL    K     AVRLD  +       G+   ++  G Y  A  
Sbjct: 794 AETGSNMNDLKELLEKSLHCLKK-----AVRLDSNNHLYWNALGVVACYSGIGNYALAQH 848

Query: 510 CFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYI 556
           CF  ++     + + W  LG         E+A  A++ A  L P Y+
Sbjct: 849 CFIKSIQSEQINAVAWTNLGVLYLTNENIEQAHEAFKMAQSLDPSYL 895



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 26/89 (29%), Positives = 39/89 (43%), Gaps = 6/89 (6%)

Query: 477 AAVRLDPTSIDPDVQC--GLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLAN 534
           AA+R DP     D  C   LG  +   G Y  A+  FT A  + P       K+ A    
Sbjct: 589 AALRADPK----DFNCWESLGEAYLSRGGYTTALKSFTKASELNPESIYSVFKVAAIQQI 644

Query: 535 GNQSEEAVAAYRRALELQPGYIRSRYNLG 563
             + +EAVA Y+  ++ +  Y+ +   LG
Sbjct: 645 LGKYKEAVAQYQMIIKKKEDYVPALKGLG 673


>gi|118766328 transmembrane and tetratricopeptide repeat containing
           4 isoform 2 [Homo sapiens]
          Length = 741

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 61/270 (22%), Positives = 103/270 (38%), Gaps = 28/270 (10%)

Query: 346 LQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTA 405
           L+ G+  +   LF +A+   P + +    +G   A+   +  AI   R  + L P    A
Sbjct: 459 LRSGEWRSEEQLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHA 518

Query: 406 LMALAVSFTNESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSD 465
           +  L       +  ++A E L   ++  P +A         A    LG        ++ +
Sbjct: 519 MNNLGNILKERNELQEAEELLSLAVQIQPDFA---------AAWMNLG--------IVQN 561

Query: 466 SLFLEVKELFLAAVRLDPTSID-----PDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPN 520
           SL     + F AA +   T+I      PD    LG L+     +  A++ +  A  ++P 
Sbjct: 562 SL-----KRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPE 616

Query: 521 DYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFL 580
             L WN +   L N     +A A  R ALEL P      ++L         ++E+   FL
Sbjct: 617 HSLAWNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEALFL 676

Query: 581 EALNMQRKSRGPRGEGGAMSENIWSTLRLA 610
           +A+     +    G    +    W  L LA
Sbjct: 677 KAIKANPNAASYHGNLAVLYHR-WGHLDLA 705



 Score = 38.5 bits (88), Expect = 0.019
 Identities = 55/269 (20%), Positives = 103/269 (38%), Gaps = 31/269 (11%)

Query: 342 GLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPD 401
           G     +G+   A+  +  AV+ +PK++ A   LG    E  +   A   L   ++++PD
Sbjct: 489 GKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPD 548

Query: 402 NQTALMALAVSFTNESLQR-QACE-----TLRDWLRYTPAYAHLVTPAEEGAGGAGLGPS 455
              A M L +     SL+R +A E      ++   +Y   Y +                 
Sbjct: 549 FAAAWMNLGI--VQNSLKRFEAAEQSYRTAIKHRRKYPDCYYN----------------- 589

Query: 456 KRILGSLLSD-SLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAA 514
              LG L +D +  ++    +  A  L P          + +L + +G   +A      A
Sbjct: 590 ---LGRLYADLNRHVDALNAWRNATVLKPE--HSLAWNNMIILLDNTGNLAQAEAVGREA 644

Query: 515 LSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHRE 574
           L + PND+ L   L   L    + +E+ A + +A++  P       NL +     G    
Sbjct: 645 LELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGHLDL 704

Query: 575 AVEHFLEALNMQRKSRGPRGEGGAMSENI 603
           A +H+  +L +   + G +   G +   +
Sbjct: 705 AKKHYEISLQLDPTASGTKENYGLLRRKL 733


>gi|118766330 transmembrane and tetratricopeptide repeat containing
           4 isoform 1 [Homo sapiens]
          Length = 760

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 61/270 (22%), Positives = 103/270 (38%), Gaps = 28/270 (10%)

Query: 346 LQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTA 405
           L+ G+  +   LF +A+   P + +    +G   A+   +  AI   R  + L P    A
Sbjct: 478 LRSGEWRSEEQLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHA 537

Query: 406 LMALAVSFTNESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSD 465
           +  L       +  ++A E L   ++  P +A         A    LG        ++ +
Sbjct: 538 MNNLGNILKERNELQEAEELLSLAVQIQPDFA---------AAWMNLG--------IVQN 580

Query: 466 SLFLEVKELFLAAVRLDPTSID-----PDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPN 520
           SL     + F AA +   T+I      PD    LG L+     +  A++ +  A  ++P 
Sbjct: 581 SL-----KRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPE 635

Query: 521 DYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFL 580
             L WN +   L N     +A A  R ALEL P      ++L         ++E+   FL
Sbjct: 636 HSLAWNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEALFL 695

Query: 581 EALNMQRKSRGPRGEGGAMSENIWSTLRLA 610
           +A+     +    G    +    W  L LA
Sbjct: 696 KAIKANPNAASYHGNLAVLYHR-WGHLDLA 724



 Score = 38.5 bits (88), Expect = 0.019
 Identities = 55/269 (20%), Positives = 103/269 (38%), Gaps = 31/269 (11%)

Query: 342 GLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPD 401
           G     +G+   A+  +  AV+ +PK++ A   LG    E  +   A   L   ++++PD
Sbjct: 508 GKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPD 567

Query: 402 NQTALMALAVSFTNESLQR-QACE-----TLRDWLRYTPAYAHLVTPAEEGAGGAGLGPS 455
              A M L +     SL+R +A E      ++   +Y   Y +                 
Sbjct: 568 FAAAWMNLGI--VQNSLKRFEAAEQSYRTAIKHRRKYPDCYYN----------------- 608

Query: 456 KRILGSLLSD-SLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAA 514
              LG L +D +  ++    +  A  L P          + +L + +G   +A      A
Sbjct: 609 ---LGRLYADLNRHVDALNAWRNATVLKPE--HSLAWNNMIILLDNTGNLAQAEAVGREA 663

Query: 515 LSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHRE 574
           L + PND+ L   L   L    + +E+ A + +A++  P       NL +     G    
Sbjct: 664 LELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGHLDL 723

Query: 575 AVEHFLEALNMQRKSRGPRGEGGAMSENI 603
           A +H+  +L +   + G +   G +   +
Sbjct: 724 AKKHYEISLQLDPTASGTKENYGLLRRKL 752


>gi|118402596 cell division cycle protein 23 [Homo sapiens]
          Length = 597

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 21/72 (29%), Positives = 34/72 (47%)

Query: 492 CGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALEL 551
           C +G  ++L  +++KA   F  AL + P     W  +G        +  A+ AYR A+E+
Sbjct: 335 CVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEV 394

Query: 552 QPGYIRSRYNLG 563
                R+ Y LG
Sbjct: 395 NKRDYRAWYGLG 406



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 16/60 (26%), Positives = 30/60 (50%)

Query: 354 AVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSF 413
           A L F+ A++ +P+++ AW  +G    E +    AI A R  +E+   +  A   L  ++
Sbjct: 350 AALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTY 409


>gi|6912398 general transcription factor IIIC, polypeptide 3, 102kDa
           [Homo sapiens]
          Length = 886

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 22/100 (22%), Positives = 47/100 (47%)

Query: 494 LGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQP 553
           L +++   G+ +K++     A  + P+D   W +L       +  ++A+  Y +AL+ +P
Sbjct: 189 LAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLAEMSLEQDNIKQAIFCYTKALKYEP 248

Query: 554 GYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPR 593
             +R  +        +G H+ A++ +   LN+   S G R
Sbjct: 249 TNVRYLWERSSLYEQMGDHKMAMDGYRRILNLLSPSDGER 288


>gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens]
          Length = 313

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 24/78 (30%), Positives = 39/78 (50%)

Query: 492 CGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALEL 551
           C     ++  G Y  AV     A+ + P     + ++G  L++ N+  EAVA Y++ALEL
Sbjct: 129 CNRAAAYSKLGNYAGAVQDCERAICIDPAYSKAYGRMGLALSSLNKHVEAVAYYKKALEL 188

Query: 552 QPGYIRSRYNLGISCINL 569
            P     + NL I+ + L
Sbjct: 189 DPDNETYKSNLKIAELKL 206



 Score = 34.3 bits (77), Expect = 0.36
 Identities = 23/83 (27%), Positives = 42/83 (50%), Gaps = 2/83 (2%)

Query: 504 YDKAVDCFTAALSVRP-NDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNL 562
           ++ AV  +  A+ + P N     N+  A    GN +  AV    RA+ + P Y ++   +
Sbjct: 107 FEAAVHFYGKAIELNPANAVYFCNRAAAYSKLGNYAG-AVQDCERAICIDPAYSKAYGRM 165

Query: 563 GISCINLGAHREAVEHFLEALNM 585
           G++  +L  H EAV ++ +AL +
Sbjct: 166 GLALSSLNKHVEAVAYYKKALEL 188



 Score = 33.5 bits (75), Expect = 0.62
 Identities = 17/56 (30%), Positives = 31/56 (55%)

Query: 349 GDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQT 404
           G+   AV   E A+  DP + +A+  +G   +   + + A++  ++ LEL PDN+T
Sbjct: 139 GNYAGAVQDCERAICIDPAYSKAYGRMGLALSSLNKHVEAVAYYKKALELDPDNET 194


>gi|24308141 small glutamine-rich tetratricopeptide repeat
           (TPR)-containing, beta [Homo sapiens]
          Length = 304

 Score = 39.3 bits (90), Expect = 0.011
 Identities = 20/82 (24%), Positives = 41/82 (50%)

Query: 504 YDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLG 563
           Y  AVDC+T A+ + PN+ + +    A  +      +A+    +A+ +   Y ++   +G
Sbjct: 101 YAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMG 160

Query: 564 ISCINLGAHREAVEHFLEALNM 585
           ++   L    EAV  + +AL++
Sbjct: 161 LALTALNKFEEAVTSYQKALDL 182



 Score = 37.0 bits (84), Expect = 0.056
 Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 2/93 (2%)

Query: 473 ELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATL 532
           + +  A+ LDP +      C      +  G Y  A+     A+++       + ++G  L
Sbjct: 106 DCYTQAIELDPNNAV--YYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLAL 163

Query: 533 ANGNQSEEAVAAYRRALELQPGYIRSRYNLGIS 565
              N+ EEAV +Y++AL+L P     + NL I+
Sbjct: 164 TALNKFEEAVTSYQKALDLDPENDSYKSNLKIA 196


>gi|56181387 STIP1 homology and U-box containing protein 1 [Homo
           sapiens]
          Length = 303

 Score = 38.9 bits (89), Expect = 0.015
 Identities = 27/108 (25%), Positives = 53/108 (49%), Gaps = 6/108 (5%)

Query: 503 EYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNL 562
           +Y +A  C+  A++  P   + +           Q E+A+A  RRALEL    +++ + L
Sbjct: 41  KYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQALADCRRALELDGQSVKAHFFL 100

Query: 563 GISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMSENIWSTLRLA 610
           G   + + ++ EA+ +   A ++ ++ R   G      ++I S LR+A
Sbjct: 101 GQCQLEMESYDEAIANLQRAYSLAKEQRLNFG------DDIPSALRIA 142


>gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo
            sapiens]
          Length = 1614

 Score = 38.5 bits (88), Expect = 0.019
 Identities = 23/90 (25%), Positives = 46/90 (51%), Gaps = 3/90 (3%)

Query: 503  EYDKAVDCFTAALSVRP---NDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSR 559
            E+++AV+ FT AL + P   + Y+          +   +++A   + +AL + P YI++R
Sbjct: 1319 EFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKAR 1378

Query: 560  YNLGISCINLGAHREAVEHFLEALNMQRKS 589
             + G +    G  ++A  HF  A++   K+
Sbjct: 1379 ISFGYNLQAQGKFQKAWNHFTIAIDTDPKN 1408



 Score = 35.0 bits (79), Expect = 0.21
 Identities = 18/50 (36%), Positives = 29/50 (58%)

Query: 503  EYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQ 552
            +Y+ A +    ALS++PND L++N            EEA+A Y +AL+L+
Sbjct: 1559 QYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLE 1608



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 21/89 (23%), Positives = 39/89 (43%)

Query: 349  GDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMA 408
            G   NA+  ++ A+  +PK+  A+   G     + Q   A     + L+  P+N+  LM 
Sbjct: 1456 GHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMN 1515

Query: 409  LAVSFTNESLQRQACETLRDWLRYTPAYA 437
             A++ T      +A E   + +   P +A
Sbjct: 1516 RAITNTILKKYEEAKEDFANVIESCPFWA 1544


>gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo
            sapiens]
          Length = 1614

 Score = 38.5 bits (88), Expect = 0.019
 Identities = 23/90 (25%), Positives = 46/90 (51%), Gaps = 3/90 (3%)

Query: 503  EYDKAVDCFTAALSVRP---NDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSR 559
            E+++AV+ FT AL + P   + Y+          +   +++A   + +AL + P YI++R
Sbjct: 1319 EFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKAR 1378

Query: 560  YNLGISCINLGAHREAVEHFLEALNMQRKS 589
             + G +    G  ++A  HF  A++   K+
Sbjct: 1379 ISFGYNLQAQGKFQKAWNHFTIAIDTDPKN 1408



 Score = 35.0 bits (79), Expect = 0.21
 Identities = 18/50 (36%), Positives = 29/50 (58%)

Query: 503  EYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQ 552
            +Y+ A +    ALS++PND L++N            EEA+A Y +AL+L+
Sbjct: 1559 QYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLE 1608



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 21/89 (23%), Positives = 39/89 (43%)

Query: 349  GDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMA 408
            G   NA+  ++ A+  +PK+  A+   G     + Q   A     + L+  P+N+  LM 
Sbjct: 1456 GHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMN 1515

Query: 409  LAVSFTNESLQRQACETLRDWLRYTPAYA 437
             A++ T      +A E   + +   P +A
Sbjct: 1516 RAITNTILKKYEEAKEDFANVIESCPFWA 1544


>gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Homo
            sapiens]
          Length = 1614

 Score = 38.5 bits (88), Expect = 0.019
 Identities = 23/90 (25%), Positives = 46/90 (51%), Gaps = 3/90 (3%)

Query: 503  EYDKAVDCFTAALSVRP---NDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSR 559
            E+++AV+ FT AL + P   + Y+          +   +++A   + +AL + P YI++R
Sbjct: 1319 EFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKAR 1378

Query: 560  YNLGISCINLGAHREAVEHFLEALNMQRKS 589
             + G +    G  ++A  HF  A++   K+
Sbjct: 1379 ISFGYNLQAQGKFQKAWNHFTIAIDTDPKN 1408



 Score = 35.0 bits (79), Expect = 0.21
 Identities = 18/50 (36%), Positives = 29/50 (58%)

Query: 503  EYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQ 552
            +Y+ A +    ALS++PND L++N            EEA+A Y +AL+L+
Sbjct: 1559 QYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLE 1608



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 21/89 (23%), Positives = 39/89 (43%)

Query: 349  GDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMA 408
            G   NA+  ++ A+  +PK+  A+   G     + Q   A     + L+  P+N+  LM 
Sbjct: 1456 GHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMN 1515

Query: 409  LAVSFTNESLQRQACETLRDWLRYTPAYA 437
             A++ T      +A E   + +   P +A
Sbjct: 1516 RAITNTILKKYEEAKEDFANVIESCPFWA 1544


>gi|157266273 RANBP2-like and GRIP domain containing 1 [Homo
           sapiens]
          Length = 1756

 Score = 38.5 bits (88), Expect = 0.019
 Identities = 34/112 (30%), Positives = 49/112 (43%), Gaps = 8/112 (7%)

Query: 449 GAGLGPSKRILGSLLSDSLFLEVKELFLA----AVRLDPTSIDPDVQCGLGVLFNLSGEY 504
           G+   P K++ G   +  L+ E KE  LA       L     DP     LG+L+ L    
Sbjct: 17  GSAPSPGKKLRGFYFA-KLYYEAKEYDLAKKYVCTYLSVQERDPRAHRFLGLLYELEENT 75

Query: 505 DKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAY--RRALELQPG 554
           +KAV+C+  +L + P    L  K+   L   N   +  A Y   RA +L PG
Sbjct: 76  EKAVECYRRSLELNPPQKDLVLKIAELLCK-NDVTDGRAKYWVERAAKLFPG 126


>gi|221307607 RANBP2-like and GRIP domain containing 3 [Homo
           sapiens]
          Length = 1758

 Score = 38.1 bits (87), Expect = 0.025
 Identities = 31/112 (27%), Positives = 48/112 (42%), Gaps = 7/112 (6%)

Query: 449 GAGLGPSKRILGSLLSDSLFLEVKELFLA----AVRLDPTSIDPDVQCGLGVLFNLSGEY 504
           G+   P K+         L+ E KE  LA       ++   +DP     LG+L+ L    
Sbjct: 17  GSAPSPRKKSTRGFYFAKLYYEAKEYDLAKKYICTYINVREMDPRAHRFLGLLYELEENT 76

Query: 505 DKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAY--RRALELQPG 554
           +KAV+C+  ++ + P    L  K+   L   N   +  A Y   RA +L PG
Sbjct: 77  EKAVECYRRSVELNPTQKDLVLKIAELLCK-NDVTDGRAEYWVERAAKLFPG 127


>gi|211059431 RANBP2-like and GRIP domain containing 4 [Homo
           sapiens]
          Length = 1758

 Score = 38.1 bits (87), Expect = 0.025
 Identities = 31/112 (27%), Positives = 48/112 (42%), Gaps = 7/112 (6%)

Query: 449 GAGLGPSKRILGSLLSDSLFLEVKELFLA----AVRLDPTSIDPDVQCGLGVLFNLSGEY 504
           G+   P K+         L+ E KE  LA       ++   +DP     LG+L+ L    
Sbjct: 17  GSAPSPRKKSTRGFYFAKLYYEAKEYDLAKKYICTYINVREMDPRAHRFLGLLYELEENT 76

Query: 505 DKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAY--RRALELQPG 554
           +KAV+C+  ++ + P    L  K+   L   N   +  A Y   RA +L PG
Sbjct: 77  EKAVECYRRSVELNPTQKDLVLKIAELLCK-NDVTDGRAKYWVERAAKLFPG 127


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.131    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,172,891
Number of Sequences: 37866
Number of extensions: 1174925
Number of successful extensions: 3801
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 56
Number of HSP's that attempted gapping in prelim test: 3464
Number of HSP's gapped (non-prelim): 323
length of query: 639
length of database: 18,247,518
effective HSP length: 109
effective length of query: 530
effective length of database: 14,120,124
effective search space: 7483665720
effective search space used: 7483665720
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.