Guide to the Human Genome
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Search of human proteins with 194578888

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194578888 calmegin [Homo sapiens]
         (610 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194578888 calmegin [Homo sapiens]                                 1277   0.0  
gi|4758004 calmegin [Homo sapiens]                                   1277   0.0  
gi|66933005 calnexin precursor [Homo sapiens]                         725   0.0  
gi|10716563 calnexin precursor [Homo sapiens]                         725   0.0  
gi|4757900 calreticulin precursor [Homo sapiens]                      256   4e-68
gi|187608348 calreticulin 3 [Homo sapiens]                            148   1e-35
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi...    51   4e-06
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is...    50   8e-06
gi|156142197 euchromatic histone-lysine N-methyltransferase 2 is...    50   8e-06
gi|221219020 NYD-SP11 protein [Homo sapiens]                           49   1e-05
gi|17975763 myelin transcription factor 1 [Homo sapiens]               49   1e-05
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    49   1e-05
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]     49   2e-05
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]     49   2e-05
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof...    49   2e-05
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof...    49   2e-05
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof...    49   2e-05
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof...    49   2e-05
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof...    49   2e-05
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    47   4e-05
gi|21361639 DIPB protein [Homo sapiens]                                47   5e-05
gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens]     47   5e-05
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof...    47   5e-05
gi|21237808 SWI/SNF-related matrix-associated actin-dependent re...    46   9e-05
gi|21237805 SWI/SNF-related matrix-associated actin-dependent re...    46   9e-05
gi|194363725 SWI/SNF-related matrix-associated actin-dependent r...    46   9e-05
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]           46   9e-05
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]           46   9e-05
gi|21735415 centromere protein B [Homo sapiens]                        45   2e-04
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m...    45   3e-04

>gi|194578888 calmegin [Homo sapiens]
          Length = 610

 Score = 1277 bits (3304), Expect = 0.0
 Identities = 610/610 (100%), Positives = 610/610 (100%)

Query: 1   MHFQAFWLCLGLLFISINAEFMDDDVETEDFEENSEEIDVNESELSSEIKYKTPQPIGEV 60
           MHFQAFWLCLGLLFISINAEFMDDDVETEDFEENSEEIDVNESELSSEIKYKTPQPIGEV
Sbjct: 1   MHFQAFWLCLGLLFISINAEFMDDDVETEDFEENSEEIDVNESELSSEIKYKTPQPIGEV 60

Query: 61  YFAETFDSGRLAGWVLSKAKKDDMDEEISIYDGRWEIEELKENQVPGDRGLVLKSRAKHH 120
           YFAETFDSGRLAGWVLSKAKKDDMDEEISIYDGRWEIEELKENQVPGDRGLVLKSRAKHH
Sbjct: 61  YFAETFDSGRLAGWVLSKAKKDDMDEEISIYDGRWEIEELKENQVPGDRGLVLKSRAKHH 120

Query: 121 AISAVLAKPFIFADKPLIVQYEVNFQDGIDCGGAYIKLLADTDDLILENFYDKTSYIIMF 180
           AISAVLAKPFIFADKPLIVQYEVNFQDGIDCGGAYIKLLADTDDLILENFYDKTSYIIMF
Sbjct: 121 AISAVLAKPFIFADKPLIVQYEVNFQDGIDCGGAYIKLLADTDDLILENFYDKTSYIIMF 180

Query: 181 GPDKCGEDYKLHFIFRHKHPKTGVFEEKHAKPPDVDLKKFFTDRKTHLYTLVMNPDDTFE 240
           GPDKCGEDYKLHFIFRHKHPKTGVFEEKHAKPPDVDLKKFFTDRKTHLYTLVMNPDDTFE
Sbjct: 181 GPDKCGEDYKLHFIFRHKHPKTGVFEEKHAKPPDVDLKKFFTDRKTHLYTLVMNPDDTFE 240

Query: 241 VLVDQTVVNKGSLLEDVVPPIKPPKEIEDPNDKKPEEWDERAKIPDPSAVKPEDWDESEP 300
           VLVDQTVVNKGSLLEDVVPPIKPPKEIEDPNDKKPEEWDERAKIPDPSAVKPEDWDESEP
Sbjct: 241 VLVDQTVVNKGSLLEDVVPPIKPPKEIEDPNDKKPEEWDERAKIPDPSAVKPEDWDESEP 300

Query: 301 AQIEDSSVVKPAGWLDDEPKFIPDPNAEKPDDWNEDTDGEWEAPQILNPACRIGCGEWKP 360
           AQIEDSSVVKPAGWLDDEPKFIPDPNAEKPDDWNEDTDGEWEAPQILNPACRIGCGEWKP
Sbjct: 301 AQIEDSSVVKPAGWLDDEPKFIPDPNAEKPDDWNEDTDGEWEAPQILNPACRIGCGEWKP 360

Query: 361 PMIDNPKYKGVWRPPLVDNPNYQGIWSPRKIPNPDYFEDDHPFLLTSFSALGLELWSMTS 420
           PMIDNPKYKGVWRPPLVDNPNYQGIWSPRKIPNPDYFEDDHPFLLTSFSALGLELWSMTS
Sbjct: 361 PMIDNPKYKGVWRPPLVDNPNYQGIWSPRKIPNPDYFEDDHPFLLTSFSALGLELWSMTS 420

Query: 421 DIYFDNFIICSEKEVADHWAADGWRWKIMIANANKPGVLKQLMAAAEGHPWLWLIYLVTA 480
           DIYFDNFIICSEKEVADHWAADGWRWKIMIANANKPGVLKQLMAAAEGHPWLWLIYLVTA
Sbjct: 421 DIYFDNFIICSEKEVADHWAADGWRWKIMIANANKPGVLKQLMAAAEGHPWLWLIYLVTA 480

Query: 481 GVPIALITSFCWPRKVKKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEEK 540
           GVPIALITSFCWPRKVKKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEEK
Sbjct: 481 GVPIALITSFCWPRKVKKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEEK 540

Query: 541 KQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKSGSEDEMKEADESTGSGDGPIK 600
           KQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKSGSEDEMKEADESTGSGDGPIK
Sbjct: 541 KQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKSGSEDEMKEADESTGSGDGPIK 600

Query: 601 SVRKRRVRKD 610
           SVRKRRVRKD
Sbjct: 601 SVRKRRVRKD 610


>gi|4758004 calmegin [Homo sapiens]
          Length = 610

 Score = 1277 bits (3304), Expect = 0.0
 Identities = 610/610 (100%), Positives = 610/610 (100%)

Query: 1   MHFQAFWLCLGLLFISINAEFMDDDVETEDFEENSEEIDVNESELSSEIKYKTPQPIGEV 60
           MHFQAFWLCLGLLFISINAEFMDDDVETEDFEENSEEIDVNESELSSEIKYKTPQPIGEV
Sbjct: 1   MHFQAFWLCLGLLFISINAEFMDDDVETEDFEENSEEIDVNESELSSEIKYKTPQPIGEV 60

Query: 61  YFAETFDSGRLAGWVLSKAKKDDMDEEISIYDGRWEIEELKENQVPGDRGLVLKSRAKHH 120
           YFAETFDSGRLAGWVLSKAKKDDMDEEISIYDGRWEIEELKENQVPGDRGLVLKSRAKHH
Sbjct: 61  YFAETFDSGRLAGWVLSKAKKDDMDEEISIYDGRWEIEELKENQVPGDRGLVLKSRAKHH 120

Query: 121 AISAVLAKPFIFADKPLIVQYEVNFQDGIDCGGAYIKLLADTDDLILENFYDKTSYIIMF 180
           AISAVLAKPFIFADKPLIVQYEVNFQDGIDCGGAYIKLLADTDDLILENFYDKTSYIIMF
Sbjct: 121 AISAVLAKPFIFADKPLIVQYEVNFQDGIDCGGAYIKLLADTDDLILENFYDKTSYIIMF 180

Query: 181 GPDKCGEDYKLHFIFRHKHPKTGVFEEKHAKPPDVDLKKFFTDRKTHLYTLVMNPDDTFE 240
           GPDKCGEDYKLHFIFRHKHPKTGVFEEKHAKPPDVDLKKFFTDRKTHLYTLVMNPDDTFE
Sbjct: 181 GPDKCGEDYKLHFIFRHKHPKTGVFEEKHAKPPDVDLKKFFTDRKTHLYTLVMNPDDTFE 240

Query: 241 VLVDQTVVNKGSLLEDVVPPIKPPKEIEDPNDKKPEEWDERAKIPDPSAVKPEDWDESEP 300
           VLVDQTVVNKGSLLEDVVPPIKPPKEIEDPNDKKPEEWDERAKIPDPSAVKPEDWDESEP
Sbjct: 241 VLVDQTVVNKGSLLEDVVPPIKPPKEIEDPNDKKPEEWDERAKIPDPSAVKPEDWDESEP 300

Query: 301 AQIEDSSVVKPAGWLDDEPKFIPDPNAEKPDDWNEDTDGEWEAPQILNPACRIGCGEWKP 360
           AQIEDSSVVKPAGWLDDEPKFIPDPNAEKPDDWNEDTDGEWEAPQILNPACRIGCGEWKP
Sbjct: 301 AQIEDSSVVKPAGWLDDEPKFIPDPNAEKPDDWNEDTDGEWEAPQILNPACRIGCGEWKP 360

Query: 361 PMIDNPKYKGVWRPPLVDNPNYQGIWSPRKIPNPDYFEDDHPFLLTSFSALGLELWSMTS 420
           PMIDNPKYKGVWRPPLVDNPNYQGIWSPRKIPNPDYFEDDHPFLLTSFSALGLELWSMTS
Sbjct: 361 PMIDNPKYKGVWRPPLVDNPNYQGIWSPRKIPNPDYFEDDHPFLLTSFSALGLELWSMTS 420

Query: 421 DIYFDNFIICSEKEVADHWAADGWRWKIMIANANKPGVLKQLMAAAEGHPWLWLIYLVTA 480
           DIYFDNFIICSEKEVADHWAADGWRWKIMIANANKPGVLKQLMAAAEGHPWLWLIYLVTA
Sbjct: 421 DIYFDNFIICSEKEVADHWAADGWRWKIMIANANKPGVLKQLMAAAEGHPWLWLIYLVTA 480

Query: 481 GVPIALITSFCWPRKVKKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEEK 540
           GVPIALITSFCWPRKVKKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEEK
Sbjct: 481 GVPIALITSFCWPRKVKKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEEK 540

Query: 541 KQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKSGSEDEMKEADESTGSGDGPIK 600
           KQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKSGSEDEMKEADESTGSGDGPIK
Sbjct: 541 KQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKSGSEDEMKEADESTGSGDGPIK 600

Query: 601 SVRKRRVRKD 610
           SVRKRRVRKD
Sbjct: 601 SVRKRRVRKD 610


>gi|66933005 calnexin precursor [Homo sapiens]
          Length = 592

 Score =  725 bits (1871), Expect = 0.0
 Identities = 340/586 (58%), Positives = 434/586 (74%), Gaps = 25/586 (4%)

Query: 8   LCLGLLFISINAEFMDDDVETED-FEENSEEIDVNESEL-----SSEIKYKTPQPIGEVY 61
           L LG   +  +    DD ++ ED  ++  EE++ ++ +      S ++ YK P P GEVY
Sbjct: 11  LVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTYKAPVPTGEVY 70

Query: 62  FAETFDSGRLAGWVLSKAKKDDMDEEISIYDGRWEIEELKENQVPGDRGLVLKSRAKHHA 121
           FA++FD G L+GW+LSKAKKDD D+EI+ YDG+WE+EE+KE+++PGD+GLVL SRAKHHA
Sbjct: 71  FADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGLVLMSRAKHHA 130

Query: 122 ISAVLAKPFIFADKPLIVQYEVNFQDGIDCGGAYIKLLADTDDLILENFYDKTSYIIMFG 181
           ISA L KPF+F  KPLIVQYEVNFQ+GI+CGGAY+KLL+ T +L L+ F+DKT Y IMFG
Sbjct: 131 ISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFHDKTPYTIMFG 190

Query: 182 PDKCGEDYKLHFIFRHKHPKTGVFEEKHAKPPDVDLKKFFTDRKTHLYTLVMNPDDTFEV 241
           PDKCGEDYKLHFIFRHK+PKTG++EEKHAK PD DLK +FTD+KTHLYTL++NPD++FE+
Sbjct: 191 PDKCGEDYKLHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEI 250

Query: 242 LVDQTVVNKGSLLEDVVPPIKPPKEIEDPNDKKPEEWDERAKIPDPSAVKPEDWDESEPA 301
           LVDQ+VVN G+LL D+ PP+ P +EIEDP D+KPE+WDER KIPDP AVKP+DWDE  PA
Sbjct: 251 LVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPEAVKPDDWDEDAPA 310

Query: 302 QIEDSSVVKPAGWLDDEPKFIPDPNAEKPDDWNEDTDGEWEAPQILNPACRI--GCGEWK 359
           +I D    KP GWLDDEP+++PDP+AEKP+DW+ED DGEWEAPQI NP C    GCG W+
Sbjct: 311 KIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPRCESAPGCGVWQ 370

Query: 360 PPMIDNPKYKGVWRPPLVDNPNYQGIWSPRKIPNPDYFEDDHPFLLTSFSALGLELWSMT 419
            P+IDNP YKG W+PP++DNP+YQGIW PRKIPNPD+FED  PF +T FSA+GLELWSMT
Sbjct: 371 RPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFFEDLEPFRMTPFSAIGLELWSMT 430

Query: 420 SDIYFDNFIICSEKEVADHWAADGWRWKIMIANANKPGVLKQLMAAAEGHPWLWLIYLVT 479
           SDI+FDNFIIC+++ + D WA DGW  K     A +PGV+ Q++ AAE  PWLW++Y++T
Sbjct: 431 SDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEERPWLWVVYILT 490

Query: 480 AGVPIALITSFCWPRKVKKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEE 539
             +P+ L+  FC     KK+    EYKKTD   P  K     EE+EEK         EEE
Sbjct: 491 VALPVFLVILFCC--SGKKQTSGMEYKKTDAPQPDVK-----EEEEEK---------EEE 534

Query: 540 KKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKSGSEDEM 585
           K + D E  E EE+ E ++KS+ E +     +E         EDE+
Sbjct: 535 KDKGDEEE-EGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEI 579


>gi|10716563 calnexin precursor [Homo sapiens]
          Length = 592

 Score =  725 bits (1871), Expect = 0.0
 Identities = 340/586 (58%), Positives = 434/586 (74%), Gaps = 25/586 (4%)

Query: 8   LCLGLLFISINAEFMDDDVETED-FEENSEEIDVNESEL-----SSEIKYKTPQPIGEVY 61
           L LG   +  +    DD ++ ED  ++  EE++ ++ +      S ++ YK P P GEVY
Sbjct: 11  LVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTYKAPVPTGEVY 70

Query: 62  FAETFDSGRLAGWVLSKAKKDDMDEEISIYDGRWEIEELKENQVPGDRGLVLKSRAKHHA 121
           FA++FD G L+GW+LSKAKKDD D+EI+ YDG+WE+EE+KE+++PGD+GLVL SRAKHHA
Sbjct: 71  FADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGLVLMSRAKHHA 130

Query: 122 ISAVLAKPFIFADKPLIVQYEVNFQDGIDCGGAYIKLLADTDDLILENFYDKTSYIIMFG 181
           ISA L KPF+F  KPLIVQYEVNFQ+GI+CGGAY+KLL+ T +L L+ F+DKT Y IMFG
Sbjct: 131 ISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFHDKTPYTIMFG 190

Query: 182 PDKCGEDYKLHFIFRHKHPKTGVFEEKHAKPPDVDLKKFFTDRKTHLYTLVMNPDDTFEV 241
           PDKCGEDYKLHFIFRHK+PKTG++EEKHAK PD DLK +FTD+KTHLYTL++NPD++FE+
Sbjct: 191 PDKCGEDYKLHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEI 250

Query: 242 LVDQTVVNKGSLLEDVVPPIKPPKEIEDPNDKKPEEWDERAKIPDPSAVKPEDWDESEPA 301
           LVDQ+VVN G+LL D+ PP+ P +EIEDP D+KPE+WDER KIPDP AVKP+DWDE  PA
Sbjct: 251 LVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPEAVKPDDWDEDAPA 310

Query: 302 QIEDSSVVKPAGWLDDEPKFIPDPNAEKPDDWNEDTDGEWEAPQILNPACRI--GCGEWK 359
           +I D    KP GWLDDEP+++PDP+AEKP+DW+ED DGEWEAPQI NP C    GCG W+
Sbjct: 311 KIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPRCESAPGCGVWQ 370

Query: 360 PPMIDNPKYKGVWRPPLVDNPNYQGIWSPRKIPNPDYFEDDHPFLLTSFSALGLELWSMT 419
            P+IDNP YKG W+PP++DNP+YQGIW PRKIPNPD+FED  PF +T FSA+GLELWSMT
Sbjct: 371 RPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFFEDLEPFRMTPFSAIGLELWSMT 430

Query: 420 SDIYFDNFIICSEKEVADHWAADGWRWKIMIANANKPGVLKQLMAAAEGHPWLWLIYLVT 479
           SDI+FDNFIIC+++ + D WA DGW  K     A +PGV+ Q++ AAE  PWLW++Y++T
Sbjct: 431 SDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEERPWLWVVYILT 490

Query: 480 AGVPIALITSFCWPRKVKKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEE 539
             +P+ L+  FC     KK+    EYKKTD   P  K     EE+EEK         EEE
Sbjct: 491 VALPVFLVILFCC--SGKKQTSGMEYKKTDAPQPDVK-----EEEEEK---------EEE 534

Query: 540 KKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKSGSEDEM 585
           K + D E  E EE+ E ++KS+ E +     +E         EDE+
Sbjct: 535 KDKGDEEE-EGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEI 579


>gi|4757900 calreticulin precursor [Homo sapiens]
          Length = 417

 Score =  256 bits (654), Expect = 4e-68
 Identities = 172/507 (33%), Positives = 250/507 (49%), Gaps = 123/507 (24%)

Query: 60  VYFAETF--DSGRLAGWVLSKAKKDDMDEEISIYDGRWEIEELKENQVPGDRGLVLKSRA 117
           VYF E F    G  + W+ SK K D     +S   G++  +E K      D+GL     A
Sbjct: 21  VYFKEQFLDGDGWTSRWIESKHKSDFGKFVLS--SGKFYGDEEK------DKGLQTSQDA 72

Query: 118 KHHAISAVLAKPFIFADKPLIVQYEVNFQDGIDCGGAYIKLLADTDDLILENFYDKTSYI 177
           + +A+SA   +PF    + L+VQ+ V  +  IDCGG Y+KL  ++ D    + +  + Y 
Sbjct: 73  RFYALSASF-EPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPNSLDQT--DMHGDSEYN 129

Query: 178 IMFGPDKCGEDYK-LHFIFRHKHPKTGVFEEKHAKPPDVDLKKFFTDRKTHLYTLVMNPD 236
           IMFGPD CG   K +H IF +K     + ++   K           D  THLYTL++ PD
Sbjct: 130 IMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKD----------DEFTHLYTLIVRPD 179

Query: 237 DTFEVLVDQTVVNKGSLLEDVVPPIKPPKEIEDPNDKKPEEWDERAKIPDPSAVKPEDWD 296
           +T+EV +D + V  GSL +D      PPK+I+DP+  KPE+WDERAKI DP+  KPEDWD
Sbjct: 180 NTYEVKIDNSQVESGSLEDDW--DFLPPKKIKDPDASKPEDWDERAKIDDPTDSKPEDWD 237

Query: 297 ESEPAQIEDSSVVKPAGWLDDEPKFIPDPNAEKPDDWNEDTDGEWEAPQILNPACRIGCG 356
           +                     P+ IPDP+A+KP+DW+E+ DGEWE              
Sbjct: 238 K---------------------PEHIPDPDAKKPEDWDEEMDGEWE-------------- 262

Query: 357 EWKPPMIDNPKYKGVWRPPLVDNPNYQGIWSPRKIPNPDYFEDDHPFLLTSFSALGLELW 416
              PP+I NP+YKG W+P  +DNP+Y+G W   +I NP+Y  D   +   +F  LGL+LW
Sbjct: 263 ---PPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYSPDPSIYAYDNFGVLGLDLW 319

Query: 417 SMTSDIYFDNFIICSEKEVADHWAADGWRWKIMIANANKPGVLKQLMAAAEGHPWLWLIY 476
            + S   FDNF+I +++  A+ +  + W            GV K    AAE         
Sbjct: 320 QVKSGTIFDNFLITNDEAYAEEFGNETW------------GVTK----AAE--------- 354

Query: 477 LVTAGVPIALITSFCWPRKVKKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDL 536
                             K  K  +D E +            L++EE+++K   E+    
Sbjct: 355 ------------------KQMKDKQDEEQR------------LKEEEEDKKRKEEE---- 380

Query: 537 EEEKKQNDGEMLEKEEESEPEEKSEEE 563
           E E K++D +  E EE+ E +E+ EEE
Sbjct: 381 EAEDKEDDEDKDEDEEDEEDKEEDEEE 407



 Score = 36.6 bits (83), Expect = 0.069
 Identities = 21/73 (28%), Positives = 41/73 (56%), Gaps = 1/73 (1%)

Query: 514 QTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEES 573
           +T GV +  EK+ K   ++   L+EE++    +  E+ E+ E +E  +E+ E  E +EE 
Sbjct: 345 ETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEED 404

Query: 574 NQSNKSG-SEDEM 585
            + +  G ++DE+
Sbjct: 405 EEEDVPGQAKDEL 417



 Score = 34.3 bits (77), Expect = 0.34
 Identities = 22/70 (31%), Positives = 38/70 (54%), Gaps = 4/70 (5%)

Query: 521 QEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKSG 580
           +E   E   + K  + + + KQ++ + L KEEE + + K EEE E  E  E+ ++  +  
Sbjct: 340 EEFGNETWGVTKAAEKQMKDKQDEEQRL-KEEEEDKKRKEEEEAEDKEDDEDKDEDEE-- 396

Query: 581 SEDEMKEADE 590
            ++E KE DE
Sbjct: 397 -DEEDKEEDE 405


>gi|187608348 calreticulin 3 [Homo sapiens]
          Length = 384

 Score =  148 bits (374), Expect = 1e-35
 Identities = 102/338 (30%), Positives = 154/338 (45%), Gaps = 68/338 (20%)

Query: 108 DRGLVLKSRAKHHAISAVLAKPFIFADKPLIVQYEVNFQDGIDCGGAYIKLL-ADTDDLI 166
           D+GL      + +AISA   KPF    K L++QY V  +  +DCGG YIK+  AD D   
Sbjct: 63  DKGLQTTQNGRFYAISARF-KPFSNKGKTLVIQYTVKHEQKMDCGGGYIKVFPADIDQ-- 119

Query: 167 LENFYDKTSYIIMFGPDKCGEDYKLHFIFRHKHPKTGVFEEKHAKPPDVDLKKFFTDRKT 226
            +N   K+ Y IMFGPD CG D K   +  H       F+ K+ +  +  L +   D  T
Sbjct: 120 -KNLNGKSQYYIMFGPDICGFDIKKVHVILH-------FKNKYHE--NKKLIRCKVDGFT 169

Query: 227 HLYTLVMNPDDTFEVLVDQTVVNKGSLLEDVVPPIKPPKEIEDPNDKKPEEWDERAKIPD 286
           HLYTL++ PD +++V +D   +  GS+  D                     W+  +   +
Sbjct: 170 HLYTLILRPDLSYDVKIDGQSIESGSIEYD---------------------WNLTSLKKE 208

Query: 287 PSAVKPEDWDESEPAQIEDSSVVKPAGWLDDEPKFIPDPNAEKPDDWNEDTDGEWEAPQI 346
            S  + +DW++++  + +D        W     K   D +  K  DWN D DG+W AP +
Sbjct: 209 TSPAESKDWEQTKDNKAQD--------W----EKHFLDASTSKQSDWNGDLDGDWPAPML 256

Query: 347 LNPACRIGCGEWKPPMIDNPKYKGVWRPPLVDNPNYQGIWSPRKIPNPDYFEDDHPFLLT 406
                       KPP  D  K +G+          ++ +W  RK+ N DY          
Sbjct: 257 Q-----------KPPYQDGLKPEGI----------HKDVWLHRKMKNTDYLTQYDLSEFE 295

Query: 407 SFSALGLELWSMTSDIYFDNFIICSEKEVADHWAADGW 444
           +  A+GLELW + S   FDNF+I  ++E AD++    W
Sbjct: 296 NIGAIGLELWQVRSGTIFDNFLITDDEEYADNFGKATW 333


>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 123

 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 33/117 (28%), Positives = 61/117 (52%), Gaps = 10/117 (8%)

Query: 494 RKVKKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEE 553
           +K KKK K+TE  +      +T+   E+EEKE K   ++    +E++K+   +  EK +E
Sbjct: 1   KKKKKKKKETEETE------ETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKE 54

Query: 554 SEPEEKSEEEIEIIEGQEESNQSNKSGSEDEMKEADESTGSGDGPIKSVRKRRVRKD 610
            E EEK  +     + +EE  +  +   E+E +E ++     +G  +  +K+R RK+
Sbjct: 55  KEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKE----EGRRRKKKKKRRRKE 107



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 37/115 (32%), Positives = 57/115 (49%), Gaps = 24/115 (20%)

Query: 495 KVKKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEES 554
           K K+K K+ E KK      +TK   +++EKEE+    K     + KK+ + E  E+EEE 
Sbjct: 32  KRKEKRKEKEKKK------KTKETEKRKEKEEEEKKRK----RKRKKKKEEEEREEEEEE 81

Query: 555 EPEEKSEEEIEIIEGQEESNQSNKSGSEDEMKEADESTGSGDGPIKSVRKRRVRK 609
           E EEK EEE E  EG+    +  +   E+E ++            K  R+R+ +K
Sbjct: 82  EEEEKEEEEKE--EGRRRKKKKKRRRKEEEEEK------------KKKRRRKTKK 122


>gi|156142199 euchromatic histone-lysine N-methyltransferase 2
           isoform b [Homo sapiens]
          Length = 1176

 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 35/92 (38%), Positives = 48/92 (52%), Gaps = 12/92 (13%)

Query: 519 LEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNK 578
           ++ + K E  AL + +  EEE         E+EEE E EE+ EEE E  E +E  NQS++
Sbjct: 283 VDSDSKSEVEALTEQLSEEEE---------EEEEEEEEEEEEEEEEEEEEDEESGNQSDR 333

Query: 579 SGSEDEMKEADESTGSGDGP-IKSVRKRRVRK 609
           SGS    K   +     D P +K  RKRR R+
Sbjct: 334 SGSSGRRKA--KKKWRKDSPWVKPSRKRRKRE 363



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 18/64 (28%), Positives = 34/64 (53%)

Query: 546 EMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKSGSEDEMKEADESTGSGDGPIKSVRKR 605
           E ++ + +SE E  +E+  E  E +EE  +  +   E+E +E DE +G+      S  +R
Sbjct: 281 ERVDSDSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRR 340

Query: 606 RVRK 609
           + +K
Sbjct: 341 KAKK 344


>gi|156142197 euchromatic histone-lysine N-methyltransferase 2
           isoform a [Homo sapiens]
          Length = 1210

 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 35/92 (38%), Positives = 48/92 (52%), Gaps = 12/92 (13%)

Query: 519 LEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNK 578
           ++ + K E  AL + +  EEE         E+EEE E EE+ EEE E  E +E  NQS++
Sbjct: 283 VDSDSKSEVEALTEQLSEEEE---------EEEEEEEEEEEEEEEEEEEEDEESGNQSDR 333

Query: 579 SGSEDEMKEADESTGSGDGP-IKSVRKRRVRK 609
           SGS    K   +     D P +K  RKRR R+
Sbjct: 334 SGSSGRRKA--KKKWRKDSPWVKPSRKRRKRE 363



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 18/64 (28%), Positives = 34/64 (53%)

Query: 546 EMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKSGSEDEMKEADESTGSGDGPIKSVRKR 605
           E ++ + +SE E  +E+  E  E +EE  +  +   E+E +E DE +G+      S  +R
Sbjct: 281 ERVDSDSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRR 340

Query: 606 RVRK 609
           + +K
Sbjct: 341 KAKK 344


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 23/77 (29%), Positives = 51/77 (66%), Gaps = 1/77 (1%)

Query: 514  QTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEES 573
            + + +L++ EK+E  + E+  + EEE+++ + E+ E+EEE + EE+ EE+ ++ + +EE 
Sbjct: 2229 EMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEK-QVEKEEEEK 2287

Query: 574  NQSNKSGSEDEMKEADE 590
             +  K   ++E++E +E
Sbjct: 2288 KKKKKEKKKEEVQEKEE 2304



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 25/71 (35%), Positives = 41/71 (57%)

Query: 520  EQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKS 579
            E+E KEE+   EK ++ EEE+K+   +  +KEE  E EE  EE+ EI+  +E  + S++ 
Sbjct: 2266 EEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEE 2325

Query: 580  GSEDEMKEADE 590
              E+     +E
Sbjct: 2326 EEEESCSLEEE 2336



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 27/81 (33%), Positives = 46/81 (56%), Gaps = 9/81 (11%)

Query: 520  EQEEKEEKAALEKPMDLEEEKKQNDGE--MLEKEEESEPEEKSE-------EEIEIIEGQ 570
            E+EE+EE+   E   + EE K++ +GE   +EKEEE + ++K E       E+ E+ E +
Sbjct: 2250 EREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEK 2309

Query: 571  EESNQSNKSGSEDEMKEADES 591
            EE     ++ S  + +E +ES
Sbjct: 2310 EEIMSEEETESLSDEEEEEES 2330



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 26/94 (27%), Positives = 47/94 (50%), Gaps = 3/94 (3%)

Query: 497  KKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEP 556
            ++  K  E K+ D    +    +++ E EE  + E    L+E +KQ      E+EE  E 
Sbjct: 2195 RRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEE 2254

Query: 557  EEKSEEEIEIIEGQEESNQSNKSGSEDEMKEADE 590
            EE+ EEE   +  +EE  +  + G E ++++ +E
Sbjct: 2255 EEREEEE---VREEEEERKEEEEGEEKQVEKEEE 2285



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 26/99 (26%), Positives = 46/99 (46%), Gaps = 2/99 (2%)

Query: 492  WPRKVKKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKE 551
            W ++ + K  D   +K    + + +   E+   EE  +L   ++ +E     + E  E+E
Sbjct: 2197 WRKRKEAKRGDKPKEKFSSQVDEVES--EEHFSEEMESLLDELEKQESLSSEEEEEREEE 2254

Query: 552  EESEPEEKSEEEIEIIEGQEESNQSNKSGSEDEMKEADE 590
            EE E EE  EEE E  E +E   +  +   E++ K+  E
Sbjct: 2255 EEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKE 2293



 Score = 36.6 bits (83), Expect = 0.069
 Identities = 24/92 (26%), Positives = 48/92 (52%)

Query: 514  QTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEES 573
            + +G  +Q EKEE+   +K  + ++E+ Q   E+ E++EE   EE++E   +  E +E  
Sbjct: 2272 EEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESC 2331

Query: 574  NQSNKSGSEDEMKEADESTGSGDGPIKSVRKR 605
            +   +   E E+ + ++     +   KS+R R
Sbjct: 2332 SLEEEVDREKEILKKEKQFKLQEQRRKSLRGR 2363



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 18/75 (24%), Positives = 42/75 (56%)

Query: 495  KVKKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEES 554
            +V++K +  E K+  +   +T+ + ++EE+EE  +LE+ +D E+E  + + +   +E+  
Sbjct: 2298 EVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRR 2357

Query: 555  EPEEKSEEEIEIIEG 569
            +     E  + I+ G
Sbjct: 2358 KSLRGRERVLSILRG 2372



 Score = 34.3 bits (77), Expect = 0.34
 Identities = 21/97 (21%), Positives = 49/97 (50%), Gaps = 4/97 (4%)

Query: 492  WPRKVKKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKE 551
            W   +  K K+ +YK  +    + +   E EEKE++   E+   ++EE K      + ++
Sbjct: 1525 WENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVT-EEQRHIQEEHK---WARIHRK 1580

Query: 552  EESEPEEKSEEEIEIIEGQEESNQSNKSGSEDEMKEA 588
                 +++++EE ++ + +E+  Q  +  +++E K A
Sbjct: 1581 RARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLA 1617



 Score = 33.9 bits (76), Expect = 0.45
 Identities = 22/80 (27%), Positives = 45/80 (56%), Gaps = 4/80 (5%)

Query: 496  VKKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEM-LEKEEES 554
            +KKK K  E +K  + +  +    +++  +EK  L     + + KK+  GE+ + KEE++
Sbjct: 1903 IKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKA 1962

Query: 555  ---EPEEKSEEEIEIIEGQE 571
               E +  +EE++ ++EG+E
Sbjct: 1963 LNLEMKRLAEEKMRLVEGKE 1982



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 28/100 (28%), Positives = 52/100 (52%), Gaps = 18/100 (18%)

Query: 512  IPQTKGVLEQEEKE---EKAALEKPMD----LEEEKKQNDGEMLEKEEESEPEEK----- 559
            +PQ +  L+ +EKE   E   LE  M+     EEE  Q +G+++E++++   EE+     
Sbjct: 1700 LPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQ 1759

Query: 560  ----SEEEIEIIEGQEESNQSNK--SGSEDEMKEADESTG 593
                SEEE ++ + +E   Q  +  +  +++M E +E  G
Sbjct: 1760 REKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLG 1799



 Score = 31.6 bits (70), Expect = 2.2
 Identities = 26/82 (31%), Positives = 35/82 (42%), Gaps = 8/82 (9%)

Query: 514  QTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKS---EEEIEIIEGQ 570
            Q  G   +  K  K   EK +  EEEK    GE L  EEE   E+K    EE  ++ E  
Sbjct: 1469 QVHGETRKSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWE-- 1526

Query: 571  EESNQSNKSGSEDEMKEADEST 592
               N  +    E + K+ +E T
Sbjct: 1527 ---NMLSSKSKEQQYKDEEEVT 1545



 Score = 31.2 bits (69), Expect = 2.9
 Identities = 23/94 (24%), Positives = 47/94 (50%), Gaps = 5/94 (5%)

Query: 514  QTKGVLEQEEKEEKAALEKPMDLEEEKKQ--NDGEMLEKEEESEP---EEKSEEEIEIIE 568
            + K V ++EE+++K   EK  +  +EK++   + E +  EEE+E    EE+ EE   + E
Sbjct: 2276 EEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEE 2335

Query: 569  GQEESNQSNKSGSEDEMKEADESTGSGDGPIKSV 602
              +   +  K   + +++E    +  G   + S+
Sbjct: 2336 EVDREKEILKKEKQFKLQEQRRKSLRGRERVLSI 2369


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 35/133 (26%), Positives = 59/133 (44%), Gaps = 17/133 (12%)

Query: 456 PGVLKQLMAAAEGHPWLWLIYLVTAGVPIALITSFCWPRKVKKKHKDTEYKKTDICIPQT 515
           PG++  L  AAEG           A         F  P   ++  + T  +  D+C    
Sbjct: 192 PGIVHLLQEAAEG-----------AASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSL 240

Query: 516 KGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQ 575
           +    +E  ++K  L    + EEE+++ + E  ++EEE E EE+ EEE      +EE  +
Sbjct: 241 EDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEE------EEEEEE 294

Query: 576 SNKSGSEDEMKEA 588
             +   E+E +EA
Sbjct: 295 EEEEEEEEEEEEA 307



 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 24/85 (28%), Positives = 48/85 (56%)

Query: 493 PRKVKKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEE 552
           P+ ++    +   K+  I   + +   E+EE+EE+   E+  + EEE+++ + E  E+EE
Sbjct: 237 PQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEE 296

Query: 553 ESEPEEKSEEEIEIIEGQEESNQSN 577
           E E EE+ EE    +  QE+++ ++
Sbjct: 297 EEEEEEEEEEAAPDVIFQEDTSHTS 321


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
           sapiens]
          Length = 1152

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 32/83 (38%), Positives = 45/83 (54%), Gaps = 9/83 (10%)

Query: 516 KGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKE-EESEPEEKSEEEIEIIEGQEESN 574
           +G  E+EE+EE+         E E+++ +GE  E E EE E E K EEE E  EG+EE  
Sbjct: 821 EGKGEREEEEEEG--------EGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGE 872

Query: 575 QSNKSGSEDEMKEADESTGSGDG 597
           +    G E+E +   E  G G+G
Sbjct: 873 EGEGEGEEEEGEGEGEEEGEGEG 895



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 29/86 (33%), Positives = 43/86 (50%)

Query: 512 IPQTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQE 571
           + + KG  E+EE+E +   E+    EEE +  + E   K EE   E + EEE E  EG+ 
Sbjct: 819 VEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEG 878

Query: 572 ESNQSNKSGSEDEMKEADESTGSGDG 597
           E  +    G E+   E +E  G G+G
Sbjct: 879 EEEEGEGEGEEEGEGEGEEEEGEGEG 904



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 31/99 (31%), Positives = 49/99 (49%), Gaps = 8/99 (8%)

Query: 520 EQEEKEEKAALEKPMDLEE--EKKQNDGEM----LEKEEESEPEEKSEEEIEIIEGQEES 573
           EQ+E+E+    E+  ++EE  E++  +GE      E+EEE E E K E E E +EG+ E 
Sbjct: 711 EQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREK 770

Query: 574 NQSNKSGSEDEMKE--ADESTGSGDGPIKSVRKRRVRKD 610
            +  +   E   KE   +E    G+G  +    R   K+
Sbjct: 771 EEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKE 809



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 29/85 (34%), Positives = 44/85 (51%), Gaps = 1/85 (1%)

Query: 514  QTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEES 573
            + +G  E EE+E +   E+  + E E+ + +GE  E E E E EE  EE  E  EG+EE 
Sbjct: 950  EEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEG 1009

Query: 574  NQSNKSGSEDEMK-EADESTGSGDG 597
                +   E E++ E +   G G+G
Sbjct: 1010 EGEGEEEEEGEVEGEVEGEEGEGEG 1034



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 27/76 (35%), Positives = 41/76 (53%), Gaps = 2/76 (2%)

Query: 521  QEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKSG 580
            +EE+ E    +   + EEE+ + +GE  E+E E E EE+ E E E  EG+ E  +    G
Sbjct: 933  EEEEGEGEGEDGEGEGEEEEGEWEGE--EEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEG 990

Query: 581  SEDEMKEADESTGSGD 596
             E+E +E  E  G G+
Sbjct: 991  EEEEGEEEGEEEGEGE 1006



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 29/79 (36%), Positives = 45/79 (56%), Gaps = 6/79 (7%)

Query: 520 EQEEKEEKAALE-KPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEES----N 574
           E+EEKE +   E +  ++E E+++ +GE  +KEE +  EEK EEE +  EG+EE      
Sbjct: 747 EEEEKEGEGKEEGEGEEVEGEREKEEGER-KKEERAGKEEKGEEEGDQGEGEEEETEGRG 805

Query: 575 QSNKSGSEDEMKEADESTG 593
           +  + G E E  E +E  G
Sbjct: 806 EEKEEGGEVEGGEVEEGKG 824



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 28/87 (32%), Positives = 46/87 (52%), Gaps = 3/87 (3%)

Query: 514 QTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESE---PEEKSEEEIEIIEGQ 570
           + +G  E EE+E +   E+  + E E+++ +G+  E+ EE E    EE+ E E E  EG+
Sbjct: 888 EEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGE 947

Query: 571 EESNQSNKSGSEDEMKEADESTGSGDG 597
            E  +    G E+E +   E  G G+G
Sbjct: 948 GEEEEGEWEGEEEEGEGEGEEEGEGEG 974



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 24/74 (32%), Positives = 40/74 (54%), Gaps = 1/74 (1%)

Query: 521 QEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEG-QEESNQSNKS 579
           Q+E+ EK   +K     E   + + E+ EKEE  + + + +E+ E  +G Q+E NQ  + 
Sbjct: 670 QDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEE 729

Query: 580 GSEDEMKEADESTG 593
           G E+E  E +E  G
Sbjct: 730 GGEEEHGEGEEEEG 743



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 31/85 (36%), Positives = 44/85 (51%), Gaps = 8/85 (9%)

Query: 514 QTKGVLEQEEKEEKAALE-KPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEE 572
           + +G  E+EE E K   E +  + EEE ++ +GE  E+E E E EE+ E E E  EG+ E
Sbjct: 844 EEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGE 903

Query: 573 SNQSNKSGSEDEMKEADESTGSGDG 597
                  G E+   E +E  G G G
Sbjct: 904 -------GEEEGEGEGEEEEGEGKG 921



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 27/85 (31%), Positives = 44/85 (51%), Gaps = 3/85 (3%)

Query: 516 KGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQ---EE 572
           +G  E+E +E +   E+     E +++ +GE  E+E E E EE+ E E E  EG+   EE
Sbjct: 864 EGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEE 923

Query: 573 SNQSNKSGSEDEMKEADESTGSGDG 597
             +  +   E+E  E +   G G+G
Sbjct: 924 EGEEGEGEGEEEEGEGEGEDGEGEG 948



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 30/87 (34%), Positives = 44/87 (50%), Gaps = 10/87 (11%)

Query: 514 QTKGVLEQEE----KEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEG 569
           + +G  E+EE    KEE+A  E+    EEE  Q +GE    EEE+E   + +EE   +EG
Sbjct: 763 EVEGEREKEEGERKKEERAGKEEKG--EEEGDQGEGE----EEETEGRGEEKEEGGEVEG 816

Query: 570 QEESNQSNKSGSEDEMKEADESTGSGD 596
            E      +   E+E  E +E  G G+
Sbjct: 817 GEVEEGKGEREEEEEEGEGEEEEGEGE 843



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 31/97 (31%), Positives = 48/97 (49%), Gaps = 11/97 (11%)

Query: 514  QTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEG--QE 571
            + +G +E EE E +         EEE+ + +GE  EKE E E   ++ EE E  EG  QE
Sbjct: 1020 EVEGEVEGEEGEGEG--------EEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQE 1071

Query: 572  ESNQSNKSGSEDEMKEADESTGSGD-GPIKSVRKRRV 607
               + N+    +E K+  +  GS   G  K+ +K+ V
Sbjct: 1072 TGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSV 1108



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 25/95 (26%), Positives = 45/95 (47%), Gaps = 5/95 (5%)

Query: 516 KGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQ 575
           +G +E+  + EK   EK     EE K+ DGE  E++E  +  +K   +     G+EE  +
Sbjct: 683 RGEMERPGEGEKELAEK-----EEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGE 737

Query: 576 SNKSGSEDEMKEADESTGSGDGPIKSVRKRRVRKD 610
             +   + E +E  E  G  +G  + V   R +++
Sbjct: 738 GEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEE 772



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 28/79 (35%), Positives = 40/79 (50%), Gaps = 5/79 (6%)

Query: 520 EQEEKEEKAALEKPMDLEEEKKQNDGEMLEKE-EESEPEEKSEEEIEIIEGQEESNQSNK 578
           E E K E+   E   + EEE+ + +GE  E E EE E E + EEE    EG+ E  +  +
Sbjct: 916 EGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEE----EGEGEGEEEGE 971

Query: 579 SGSEDEMKEADESTGSGDG 597
              E+   E +E  G G+G
Sbjct: 972 GEGEEGEGEGEEEEGEGEG 990



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 32/85 (37%), Positives = 43/85 (50%), Gaps = 5/85 (5%)

Query: 516 KGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKE---EESEPEEKSEEEIEIIEGQEE 572
           +G  E+EE E +   E   + EEE+ + +GE  E E   EE E E K EEE E  EG+ E
Sbjct: 875 EGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEE-EGEGEGEEEEGEGKGEEEGEEGEGEGE 933

Query: 573 SNQSNKSGSEDEMKEADESTGSGDG 597
             +    G ED   E +E  G  +G
Sbjct: 934 EEEGEGEG-EDGEGEGEEEEGEWEG 957



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 29/83 (34%), Positives = 41/83 (49%), Gaps = 1/83 (1%)

Query: 516  KGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKE-EESEPEEKSEEEIEIIEGQEESN 574
            +G  E+EE E +   E+     EE+ + +GE  E E EE E E + EEE    EG+EE  
Sbjct: 945  EGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGE 1004

Query: 575  QSNKSGSEDEMKEADESTGSGDG 597
               +   E E +E  E  G  +G
Sbjct: 1005 GEEEGEGEGEEEEEGEVEGEVEG 1027



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 9/82 (10%)

Query: 516 KGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQ 575
           +G  E+EE E K         EEE ++ +GE  E+E E E E+  E E E  EG+ E  +
Sbjct: 909 EGEGEEEEGEGKG--------EEEGEEGEGEGEEEEGEGEGED-GEGEGEEEEGEWEGEE 959

Query: 576 SNKSGSEDEMKEADESTGSGDG 597
               G  +E  E +   G G+G
Sbjct: 960 EEGEGEGEEEGEGEGEEGEGEG 981



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 31/94 (32%), Positives = 46/94 (48%), Gaps = 10/94 (10%)

Query: 514  QTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEE--------KSEEEIE 565
            + +G  E EE+ E    E   + EEE+ + +GE  E EEE E E         + EEE E
Sbjct: 959  EEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEE 1018

Query: 566  -IIEGQEESNQSNKSGSEDE-MKEADESTGSGDG 597
              +EG+ E  +    G E+E  +E +E    G+G
Sbjct: 1019 GEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEG 1052



 Score = 36.6 bits (83), Expect = 0.069
 Identities = 29/83 (34%), Positives = 41/83 (49%), Gaps = 3/83 (3%)

Query: 516  KGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPE-EKSEEEIEIIEGQEESN 574
            +G  E+EE EE+   E+  + EEE +    E  E E E E E E+ E E E  EG+EE  
Sbjct: 987  EGEGEEEEGEEEG--EEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGE 1044

Query: 575  QSNKSGSEDEMKEADESTGSGDG 597
            +  K G  +E +   E     +G
Sbjct: 1045 EREKEGEGEENRRNREEEEEEEG 1067



 Score = 36.6 bits (83), Expect = 0.069
 Identities = 26/78 (33%), Positives = 40/78 (51%), Gaps = 11/78 (14%)

Query: 514  QTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEES 573
            + +G  E EE+EE    E   ++E E+ + +GE  E EEE E  EK        EG+ E 
Sbjct: 1006 EEEGEGEGEEEEEG---EVEGEVEGEEGEGEGEEEEGEEEGEEREK--------EGEGEE 1054

Query: 574  NQSNKSGSEDEMKEADES 591
            N+ N+   E+E  +  E+
Sbjct: 1055 NRRNREEEEEEEGKYQET 1072



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 24/78 (30%), Positives = 36/78 (46%)

Query: 520 EQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKS 579
           E E K E+   E   + E E+ + +GE  E E E E E + E E E  EG+ E     + 
Sbjct: 853 EGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEG 912

Query: 580 GSEDEMKEADESTGSGDG 597
             E+   + +E    G+G
Sbjct: 913 EEEEGEGKGEEEGEEGEG 930



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 26/78 (33%), Positives = 39/78 (50%), Gaps = 3/78 (3%)

Query: 516  KGVLEQEEKEEKAALEKPMDLEEEKKQNDGEML---EKEEESEPEEKSEEEIEIIEGQEE 572
            +G  E EE+E +   E+    EE +++ +GE     E EEE E E + E E E  EG+ E
Sbjct: 976  EGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGE 1035

Query: 573  SNQSNKSGSEDEMKEADE 590
              +  + G E E +   E
Sbjct: 1036 EEEGEEEGEEREKEGEGE 1053



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 22/82 (26%), Positives = 39/82 (47%)

Query: 519 LEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNK 578
           +E+  +EE    E+     EE+++ +GE  E+ E  E E + E+E    + +E + +  K
Sbjct: 727 MEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEK 786

Query: 579 SGSEDEMKEADESTGSGDGPIK 600
              E +  E +E    G G  K
Sbjct: 787 GEEEGDQGEGEEEETEGRGEEK 808



 Score = 34.3 bits (77), Expect = 0.34
 Identities = 30/85 (35%), Positives = 42/85 (49%), Gaps = 10/85 (11%)

Query: 521 QEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSE------EEIEIIEGQEESN 574
           +EE EE    E+  + E E ++ +GE  E EEE E E + E      EE    EG+EE  
Sbjct: 859 EEEGEEGEGEEEGEEGEGEGEEEEGEG-EGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEG 917

Query: 575 Q--SNKSGSEDEMKEADESTGSGDG 597
           +    + G E E  E +E  G G+G
Sbjct: 918 EGKGEEEGEEGE-GEGEEEEGEGEG 941



 Score = 33.9 bits (76), Expect = 0.45
 Identities = 24/75 (32%), Positives = 41/75 (54%), Gaps = 1/75 (1%)

Query: 514  QTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESE-PEEKSEEEIEIIEGQEE 572
            + +G  E EE+ E     +    EEE+ + +GE+  +E E E  EE+ EEE E  E + E
Sbjct: 992  EEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGE 1051

Query: 573  SNQSNKSGSEDEMKE 587
              ++ ++  E+E +E
Sbjct: 1052 GEENRRNREEEEEEE 1066



 Score = 30.8 bits (68), Expect = 3.8
 Identities = 25/84 (29%), Positives = 45/84 (53%), Gaps = 7/84 (8%)

Query: 514 QTKGVLEQE----EKEEKAALEKPMDLEEEK--KQNDGE-MLEKEEESEPEEKSEEEIEI 566
           QT G L Q+    E ++    E+  +++E K  KQ+  + +   +  +  E  S+EE+EI
Sbjct: 527 QTIGELTQDTALTENDDSDEYEEMSEMKEGKACKQHVSQGIFMTQPATTIEAFSDEEVEI 586

Query: 567 IEGQEESNQSNKSGSEDEMKEADE 590
            E +E +  S  +G E++  EA+E
Sbjct: 587 PEEKEGAEDSKGNGIEEQEVEANE 610


>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
          Length = 770

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 29/97 (29%), Positives = 48/97 (49%)

Query: 494 RKVKKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEE 553
           ++ K + +D      DI   + K    +    E  +  +  + EEE+++ +G   E+ EE
Sbjct: 241 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 300

Query: 554 SEPEEKSEEEIEIIEGQEESNQSNKSGSEDEMKEADE 590
            E EE+ EEE      +E S QS +  SE+EM E +E
Sbjct: 301 EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEE 337



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 28/85 (32%), Positives = 43/85 (50%), Gaps = 9/85 (10%)

Query: 520 EQEEKEEKAALEKPMDLEEEKKQND---GEMLEKEEESEPEEKSEEEIEIIEGQEESN-- 574
           E+EE+EE +  E+  + EEE+++ +   G   E+  E   EE SEEE+   E +E  N  
Sbjct: 285 EEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHL 344

Query: 575 ----QSNKSGSEDEMKEADESTGSG 595
               +S       E +EA+E  G G
Sbjct: 345 LVVPESRFDRDSGESEEAEEEVGEG 369



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 26/77 (33%), Positives = 40/77 (51%), Gaps = 3/77 (3%)

Query: 519 LEQEEKEEKAALEKPMDLEE-EKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSN 577
           +++E+ EE+  L    D+ + E+K +  E    E  S  EE+ EEE E  E +E S    
Sbjct: 240 VKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEE--EEEEGSTSEE 297

Query: 578 KSGSEDEMKEADESTGS 594
               E+E +E +E TGS
Sbjct: 298 SEEEEEEEEEEEEETGS 314



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 1/100 (1%)

Query: 497 KKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEP 556
           +K  K+ + ++ D+ +   + + + E K   A           +++ + E  E+EE S  
Sbjct: 237 RKPVKEEKMEERDL-LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTS 295

Query: 557 EEKSEEEIEIIEGQEESNQSNKSGSEDEMKEADESTGSGD 596
           EE  EEE E  E +EE+  +++  SE   +E  E   S D
Sbjct: 296 EESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED 335


>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
          Length = 780

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 29/97 (29%), Positives = 48/97 (49%)

Query: 494 RKVKKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEE 553
           ++ K + +D      DI   + K    +    E  +  +  + EEE+++ +G   E+ EE
Sbjct: 251 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 310

Query: 554 SEPEEKSEEEIEIIEGQEESNQSNKSGSEDEMKEADE 590
            E EE+ EEE      +E S QS +  SE+EM E +E
Sbjct: 311 EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEE 347



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 28/85 (32%), Positives = 43/85 (50%), Gaps = 9/85 (10%)

Query: 520 EQEEKEEKAALEKPMDLEEEKKQND---GEMLEKEEESEPEEKSEEEIEIIEGQEESN-- 574
           E+EE+EE +  E+  + EEE+++ +   G   E+  E   EE SEEE+   E +E  N  
Sbjct: 295 EEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHL 354

Query: 575 ----QSNKSGSEDEMKEADESTGSG 595
               +S       E +EA+E  G G
Sbjct: 355 LVVPESRFDRDSGESEEAEEEVGEG 379



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 26/77 (33%), Positives = 40/77 (51%), Gaps = 3/77 (3%)

Query: 519 LEQEEKEEKAALEKPMDLEE-EKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSN 577
           +++E+ EE+  L    D+ + E+K +  E    E  S  EE+ EEE E  E +E S    
Sbjct: 250 VKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEE--EEEEGSTSEE 307

Query: 578 KSGSEDEMKEADESTGS 594
               E+E +E +E TGS
Sbjct: 308 SEEEEEEEEEEEEETGS 324



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 1/100 (1%)

Query: 497 KKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEP 556
           +K  K+ + ++ D+ +   + + + E K   A           +++ + E  E+EE S  
Sbjct: 247 RKPVKEEKMEERDL-LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTS 305

Query: 557 EEKSEEEIEIIEGQEESNQSNKSGSEDEMKEADESTGSGD 596
           EE  EEE E  E +EE+  +++  SE   +E  E   S D
Sbjct: 306 EESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED 345


>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           9 [Homo sapiens]
          Length = 771

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 29/97 (29%), Positives = 48/97 (49%)

Query: 494 RKVKKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEE 553
           ++ K + +D      DI   + K    +    E  +  +  + EEE+++ +G   E+ EE
Sbjct: 242 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 301

Query: 554 SEPEEKSEEEIEIIEGQEESNQSNKSGSEDEMKEADE 590
            E EE+ EEE      +E S QS +  SE+EM E +E
Sbjct: 302 EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEE 338



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 28/85 (32%), Positives = 43/85 (50%), Gaps = 9/85 (10%)

Query: 520 EQEEKEEKAALEKPMDLEEEKKQND---GEMLEKEEESEPEEKSEEEIEIIEGQEESN-- 574
           E+EE+EE +  E+  + EEE+++ +   G   E+  E   EE SEEE+   E +E  N  
Sbjct: 286 EEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHL 345

Query: 575 ----QSNKSGSEDEMKEADESTGSG 595
               +S       E +EA+E  G G
Sbjct: 346 LVVPESRFDRDSGESEEAEEEVGEG 370



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 26/77 (33%), Positives = 40/77 (51%), Gaps = 3/77 (3%)

Query: 519 LEQEEKEEKAALEKPMDLEE-EKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSN 577
           +++E+ EE+  L    D+ + E+K +  E    E  S  EE+ EEE E  E +E S    
Sbjct: 241 VKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEE--EEEEGSTSEE 298

Query: 578 KSGSEDEMKEADESTGS 594
               E+E +E +E TGS
Sbjct: 299 SEEEEEEEEEEEEETGS 315



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 1/100 (1%)

Query: 497 KKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEP 556
           +K  K+ + ++ D+ +   + + + E K   A           +++ + E  E+EE S  
Sbjct: 238 RKPVKEEKMEERDL-LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTS 296

Query: 557 EEKSEEEIEIIEGQEESNQSNKSGSEDEMKEADESTGSGD 596
           EE  EEE E  E +EE+  +++  SE   +E  E   S D
Sbjct: 297 EESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED 336


>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           8 [Homo sapiens]
          Length = 780

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 29/97 (29%), Positives = 48/97 (49%)

Query: 494 RKVKKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEE 553
           ++ K + +D      DI   + K    +    E  +  +  + EEE+++ +G   E+ EE
Sbjct: 251 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 310

Query: 554 SEPEEKSEEEIEIIEGQEESNQSNKSGSEDEMKEADE 590
            E EE+ EEE      +E S QS +  SE+EM E +E
Sbjct: 311 EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEE 347



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 28/85 (32%), Positives = 43/85 (50%), Gaps = 9/85 (10%)

Query: 520 EQEEKEEKAALEKPMDLEEEKKQND---GEMLEKEEESEPEEKSEEEIEIIEGQEESN-- 574
           E+EE+EE +  E+  + EEE+++ +   G   E+  E   EE SEEE+   E +E  N  
Sbjct: 295 EEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHL 354

Query: 575 ----QSNKSGSEDEMKEADESTGSG 595
               +S       E +EA+E  G G
Sbjct: 355 LVVPESRFDRDSGESEEAEEEVGEG 379



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 26/77 (33%), Positives = 40/77 (51%), Gaps = 3/77 (3%)

Query: 519 LEQEEKEEKAALEKPMDLEE-EKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSN 577
           +++E+ EE+  L    D+ + E+K +  E    E  S  EE+ EEE E  E +E S    
Sbjct: 250 VKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEE--EEEEGSTSEE 307

Query: 578 KSGSEDEMKEADESTGS 594
               E+E +E +E TGS
Sbjct: 308 SEEEEEEEEEEEEETGS 324



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 1/100 (1%)

Query: 497 KKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEP 556
           +K  K+ + ++ D+ +   + + + E K   A           +++ + E  E+EE S  
Sbjct: 247 RKPVKEEKMEERDL-LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTS 305

Query: 557 EEKSEEEIEIIEGQEESNQSNKSGSEDEMKEADESTGSGD 596
           EE  EEE E  E +EE+  +++  SE   +E  E   S D
Sbjct: 306 EESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED 345


>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           5 [Homo sapiens]
          Length = 748

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 29/97 (29%), Positives = 48/97 (49%)

Query: 494 RKVKKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEE 553
           ++ K + +D      DI   + K    +    E  +  +  + EEE+++ +G   E+ EE
Sbjct: 219 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 278

Query: 554 SEPEEKSEEEIEIIEGQEESNQSNKSGSEDEMKEADE 590
            E EE+ EEE      +E S QS +  SE+EM E +E
Sbjct: 279 EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEE 315



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 28/85 (32%), Positives = 43/85 (50%), Gaps = 9/85 (10%)

Query: 520 EQEEKEEKAALEKPMDLEEEKKQND---GEMLEKEEESEPEEKSEEEIEIIEGQEESN-- 574
           E+EE+EE +  E+  + EEE+++ +   G   E+  E   EE SEEE+   E +E  N  
Sbjct: 263 EEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHL 322

Query: 575 ----QSNKSGSEDEMKEADESTGSG 595
               +S       E +EA+E  G G
Sbjct: 323 LVVPESRFDRDSGESEEAEEEVGEG 347



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 26/77 (33%), Positives = 40/77 (51%), Gaps = 3/77 (3%)

Query: 519 LEQEEKEEKAALEKPMDLEE-EKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSN 577
           +++E+ EE+  L    D+ + E+K +  E    E  S  EE+ EEE E  E +E S    
Sbjct: 218 VKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEE--EEEEGSTSEE 275

Query: 578 KSGSEDEMKEADESTGS 594
               E+E +E +E TGS
Sbjct: 276 SEEEEEEEEEEEEETGS 292



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 1/100 (1%)

Query: 497 KKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEP 556
           +K  K+ + ++ D+ +   + + + E K   A           +++ + E  E+EE S  
Sbjct: 215 RKPVKEEKMEERDL-LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTS 273

Query: 557 EEKSEEEIEIIEGQEESNQSNKSGSEDEMKEADESTGSGD 596
           EE  EEE E  E +EE+  +++  SE   +E  E   S D
Sbjct: 274 EESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED 313


>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           4 [Homo sapiens]
          Length = 737

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 29/97 (29%), Positives = 48/97 (49%)

Query: 494 RKVKKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEE 553
           ++ K + +D      DI   + K    +    E  +  +  + EEE+++ +G   E+ EE
Sbjct: 208 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 267

Query: 554 SEPEEKSEEEIEIIEGQEESNQSNKSGSEDEMKEADE 590
            E EE+ EEE      +E S QS +  SE+EM E +E
Sbjct: 268 EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEE 304



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 28/85 (32%), Positives = 43/85 (50%), Gaps = 9/85 (10%)

Query: 520 EQEEKEEKAALEKPMDLEEEKKQND---GEMLEKEEESEPEEKSEEEIEIIEGQEESN-- 574
           E+EE+EE +  E+  + EEE+++ +   G   E+  E   EE SEEE+   E +E  N  
Sbjct: 252 EEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHL 311

Query: 575 ----QSNKSGSEDEMKEADESTGSG 595
               +S       E +EA+E  G G
Sbjct: 312 LVVPESRFDRDSGESEEAEEEVGEG 336



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 26/77 (33%), Positives = 40/77 (51%), Gaps = 3/77 (3%)

Query: 519 LEQEEKEEKAALEKPMDLEE-EKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSN 577
           +++E+ EE+  L    D+ + E+K +  E    E  S  EE+ EEE E  E +E S    
Sbjct: 207 VKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEE--EEEEGSTSEE 264

Query: 578 KSGSEDEMKEADESTGS 594
               E+E +E +E TGS
Sbjct: 265 SEEEEEEEEEEEEETGS 281



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 1/100 (1%)

Query: 497 KKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEP 556
           +K  K+ + ++ D+ +   + + + E K   A           +++ + E  E+EE S  
Sbjct: 204 RKPVKEEKMEERDL-LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTS 262

Query: 557 EEKSEEEIEIIEGQEESNQSNKSGSEDEMKEADESTGSGD 596
           EE  EEE E  E +EE+  +++  SE   +E  E   S D
Sbjct: 263 EESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED 302


>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           2 [Homo sapiens]
          Length = 782

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 29/97 (29%), Positives = 48/97 (49%)

Query: 494 RKVKKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEE 553
           ++ K + +D      DI   + K    +    E  +  +  + EEE+++ +G   E+ EE
Sbjct: 253 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 312

Query: 554 SEPEEKSEEEIEIIEGQEESNQSNKSGSEDEMKEADE 590
            E EE+ EEE      +E S QS +  SE+EM E +E
Sbjct: 313 EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEE 349



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 28/85 (32%), Positives = 43/85 (50%), Gaps = 9/85 (10%)

Query: 520 EQEEKEEKAALEKPMDLEEEKKQND---GEMLEKEEESEPEEKSEEEIEIIEGQEESN-- 574
           E+EE+EE +  E+  + EEE+++ +   G   E+  E   EE SEEE+   E +E  N  
Sbjct: 297 EEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHL 356

Query: 575 ----QSNKSGSEDEMKEADESTGSG 595
               +S       E +EA+E  G G
Sbjct: 357 LVVPESRFDRDSGESEEAEEEVGEG 381



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 26/77 (33%), Positives = 40/77 (51%), Gaps = 3/77 (3%)

Query: 519 LEQEEKEEKAALEKPMDLEE-EKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSN 577
           +++E+ EE+  L    D+ + E+K +  E    E  S  EE+ EEE E  E +E S    
Sbjct: 252 VKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEE--EEEEGSTSEE 309

Query: 578 KSGSEDEMKEADESTGS 594
               E+E +E +E TGS
Sbjct: 310 SEEEEEEEEEEEEETGS 326



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 1/100 (1%)

Query: 497 KKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEP 556
           +K  K+ + ++ D+ +   + + + E K   A           +++ + E  E+EE S  
Sbjct: 249 RKPVKEEKMEERDL-LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTS 307

Query: 557 EEKSEEEIEIIEGQEESNQSNKSGSEDEMKEADESTGSGD 596
           EE  EEE E  E +EE+  +++  SE   +E  E   S D
Sbjct: 308 EESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED 347


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 29/83 (34%), Positives = 47/83 (56%), Gaps = 5/83 (6%)

Query: 520 EQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQ-EESNQSNK 578
           E+EE+EE+   E+  D EEE++  +      EEE E EE+ EEE E  EG+ EE  +   
Sbjct: 894 EEEEEEEEEEEEEEEDFEEEEEDEEEYF---EEEEEEEEEFEEEFEEEEGELEEEEEEED 950

Query: 579 SGSEDEMKEADE-STGSGDGPIK 600
              E+E++E ++   G+  G ++
Sbjct: 951 EEEEEELEEVEDLEFGTAGGEVE 973



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 24/70 (34%), Positives = 40/70 (57%)

Query: 520 EQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKS 579
           ++EE+EE+   E+  + EEE++  + E  ++EE  E EE+ EEE E    +EE     + 
Sbjct: 887 DEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE 946

Query: 580 GSEDEMKEAD 589
             EDE +E +
Sbjct: 947 EEEDEEEEEE 956



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 26/71 (36%), Positives = 40/71 (56%), Gaps = 7/71 (9%)

Query: 520 EQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKS 579
           E+EE+EE+       + EEE+++ + E  E+EEE E E   EEE E  E +EE  +    
Sbjct: 889 EEEEEEEE-------EEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGE 941

Query: 580 GSEDEMKEADE 590
             E+E +E +E
Sbjct: 942 LEEEEEEEDEE 952



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 5/73 (6%)

Query: 533 PMDLEEEK-----KQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKSGSEDEMKE 587
           P  LEE+        +D E  E+EEE E EE+ EEE E  E +EE  +      E+E +E
Sbjct: 871 PPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEE 930

Query: 588 ADESTGSGDGPIK 600
            +E     +G ++
Sbjct: 931 FEEEFEEEEGELE 943



 Score = 37.0 bits (84), Expect = 0.053
 Identities = 23/65 (35%), Positives = 36/65 (55%), Gaps = 1/65 (1%)

Query: 520 EQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKS 579
           E+EE++E+   E+  + EEE+ + + E  E E E E EE+ EEE E +E  E+       
Sbjct: 911 EEEEEDEEEYFEEEEE-EEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAG 969

Query: 580 GSEDE 584
           G  +E
Sbjct: 970 GEVEE 974



 Score = 30.8 bits (68), Expect = 3.8
 Identities = 19/50 (38%), Positives = 29/50 (58%)

Query: 520 EQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEG 569
           E+EE+ E+   E+  +LEEE+++ D E  E+ EE E  E      E+ EG
Sbjct: 926 EEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEG 975


>gi|21361639 DIPB protein [Homo sapiens]
          Length = 344

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 27/70 (38%), Positives = 40/70 (57%), Gaps = 3/70 (4%)

Query: 527 KAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKSGSEDEMK 586
           K   E  ++ E E +   GE  E EEESE EE+SE E E    ++ES++ ++  SE+EM+
Sbjct: 78  KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEE---SEDESDEESEEDSEEEME 134

Query: 587 EADESTGSGD 596
           +  ES    D
Sbjct: 135 DEQESEAEED 144



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 25/76 (32%), Positives = 42/76 (55%), Gaps = 1/76 (1%)

Query: 521 QEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKSG 580
           +EE E K   E+ ++ E  ++    E  E EEESE EE+SE+E +  E +E+S +  +  
Sbjct: 78  KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESD-EESEEDSEEEMEDE 136

Query: 581 SEDEMKEADESTGSGD 596
            E E +E ++  G  +
Sbjct: 137 QESEAEEDNQEEGESE 152



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 24/70 (34%), Positives = 36/70 (51%), Gaps = 2/70 (2%)

Query: 520 EQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKS 579
           E+ E EE++  E+  + EEE +    E  E EE+SE E + E+E E  E  +E  +S   
Sbjct: 97  EESESEEESESEEESETEEESEDESDE--ESEEDSEEEMEDEQESEAEEDNQEEGESEAE 154

Query: 580 GSEDEMKEAD 589
           G  +   E D
Sbjct: 155 GETEAESEFD 164



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 27/83 (32%), Positives = 44/83 (53%), Gaps = 6/83 (7%)

Query: 519 LEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNK 578
           +EQE + E  A E+    EE + + + E  E+E E E +E+SEE+ E     EE     +
Sbjct: 85  VEQEREIESEAGEESESEEESESEEESET-EEESEDESDEESEEDSE-----EEMEDEQE 138

Query: 579 SGSEDEMKEADESTGSGDGPIKS 601
           S +E++ +E  ES   G+   +S
Sbjct: 139 SEAEEDNQEEGESEAEGETEAES 161



 Score = 37.7 bits (86), Expect = 0.031
 Identities = 24/68 (35%), Positives = 38/68 (55%), Gaps = 2/68 (2%)

Query: 520 EQEEKEEKAALEKPMDLEEEKKQNDG-EMLEKEEESEPEEKSEEEIEIIEGQEESNQSNK 578
           E E +EE    E+  D  +E+ + D  E +E E+ESE EE ++EE E  E + E+   ++
Sbjct: 104 ESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGE-SEAEGETEAESE 162

Query: 579 SGSEDEMK 586
              E EM+
Sbjct: 163 FDPEIEME 170


>gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens]
          Length = 543

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 27/82 (32%), Positives = 46/82 (56%), Gaps = 1/82 (1%)

Query: 524 KEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKSGSED 583
           K E+A  E P + E E+++ D E  E+EE +E EE ++EE E  + +EE  +  + G E 
Sbjct: 462 KAEEAKDEPPSEGEAEEEEKDKEEAEEEEAAEEEEAAKEESEEAKEEEEGGE-GEEGEET 520

Query: 584 EMKEADESTGSGDGPIKSVRKR 605
           +  E +E    G G  ++ +K+
Sbjct: 521 KEAEEEEKKVEGAGEEQAAKKK 542



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 25/77 (32%), Positives = 41/77 (53%), Gaps = 3/77 (3%)

Query: 513 PQTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEE 572
           P ++G  E+EEK+++ A E+    EEE  + + E  ++EEE    E+ E   E  E +EE
Sbjct: 470 PPSEGEAEEEEKDKEEAEEEEAAEEEEAAKEESEEAKEEEEGGEGEEGE---ETKEAEEE 526

Query: 573 SNQSNKSGSEDEMKEAD 589
             +   +G E   K+ D
Sbjct: 527 EKKVEGAGEEQAAKKKD 543



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 26/83 (31%), Positives = 41/83 (49%), Gaps = 6/83 (7%)

Query: 519 LEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNK 578
           +E EE  E A  E+  D  E   + + E  EK++E   EE++ EE E  + + E  +  +
Sbjct: 452 IEVEETIEAAKAEEAKD--EPPSEGEAEEEEKDKEEAEEEEAAEEEEAAKEESEEAKEEE 509

Query: 579 SGSE----DEMKEADESTGSGDG 597
            G E    +E KEA+E     +G
Sbjct: 510 EGGEGEEGEETKEAEEEEKKVEG 532



 Score = 38.1 bits (87), Expect = 0.024
 Identities = 26/75 (34%), Positives = 40/75 (53%), Gaps = 4/75 (5%)

Query: 520 EQEEKEEKAALEKPMDLEEEKKQNDGEMLEKE---EESEPEEKSEEEIEIIEGQEESNQS 576
           EQ E EE     K  + ++E   ++GE  E+E   EE+E EE +EEE    E  EE+ + 
Sbjct: 450 EQIEVEETIEAAKAEEAKDEPP-SEGEAEEEEKDKEEAEEEEAAEEEEAAKEESEEAKEE 508

Query: 577 NKSGSEDEMKEADES 591
            + G  +E +E  E+
Sbjct: 509 EEGGEGEEGEETKEA 523



 Score = 33.9 bits (76), Expect = 0.45
 Identities = 22/74 (29%), Positives = 39/74 (52%), Gaps = 7/74 (9%)

Query: 524 KEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKSGSED 583
           +EE+  +E+ ++  + ++  D      E E+E EEK +EE E  E  EE     +  +++
Sbjct: 448 QEEQIEVEETIEAAKAEEAKDEP--PSEGEAEEEEKDKEEAEEEEAAEE-----EEAAKE 500

Query: 584 EMKEADESTGSGDG 597
           E +EA E    G+G
Sbjct: 501 ESEEAKEEEEGGEG 514


>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           3 [Homo sapiens]
          Length = 526

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 27/82 (32%), Positives = 42/82 (51%)

Query: 509 DICIPQTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIE 568
           DI   + K    +    E  +  +  + EEE+++ +G   E+ EE E EE+ EEE     
Sbjct: 12  DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSN 71

Query: 569 GQEESNQSNKSGSEDEMKEADE 590
            +E S QS +  SE+EM E +E
Sbjct: 72  SEEASEQSAEEVSEEEMSEDEE 93



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 28/85 (32%), Positives = 43/85 (50%), Gaps = 9/85 (10%)

Query: 520 EQEEKEEKAALEKPMDLEEEKKQND---GEMLEKEEESEPEEKSEEEIEIIEGQEESN-- 574
           E+EE+EE +  E+  + EEE+++ +   G   E+  E   EE SEEE+   E +E  N  
Sbjct: 41  EEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHL 100

Query: 575 ----QSNKSGSEDEMKEADESTGSG 595
               +S       E +EA+E  G G
Sbjct: 101 LVVPESRFDRDSGESEEAEEEVGEG 125



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 24/71 (33%), Positives = 37/71 (52%), Gaps = 3/71 (4%)

Query: 526 EKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKSGSEDEM 585
           E ++ E     EEE+++ + E   +EE S  EE  EEE E  E +EE+  +++  SE   
Sbjct: 24  ESSSAESGSGSEEEEEEEEEE---EEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSA 80

Query: 586 KEADESTGSGD 596
           +E  E   S D
Sbjct: 81  EEVSEEEMSED 91



 Score = 37.7 bits (86), Expect = 0.031
 Identities = 25/71 (35%), Positives = 35/71 (49%), Gaps = 3/71 (4%)

Query: 525 EEKAALEKPMDLEE-EKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKSGSED 583
           EE+  L    D+ + E+K +  E    E  S  EE+ EEE E  E +E S        E+
Sbjct: 2   EERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEE--EEEEGSTSEESEEEEE 59

Query: 584 EMKEADESTGS 594
           E +E +E TGS
Sbjct: 60  EEEEEEEETGS 70


>gi|21237808 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin c2 isoform b [Homo sapiens]
          Length = 1130

 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 12/101 (11%)

Query: 514 QTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEG---- 569
           + +G    E+KE K   E    +EEE K+   E  +K+EE   E  SE+E E  +G    
Sbjct: 791 RVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKESEKSDGDPIV 850

Query: 570 QEESNQSNKSGSEDEMKEADESTGSGDGPIKSVRKRRVRKD 610
             E  +  K G E+ +KE  ES G         RK +V +D
Sbjct: 851 DPEKEKEPKEGQEEVLKEVVESEGE--------RKTKVERD 883



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 23/80 (28%), Positives = 39/80 (48%), Gaps = 2/80 (2%)

Query: 517 GVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQS 576
           G +E+E KE+ +  E P   EE+ K+ D E   ++ + +P    E+E E  EGQEE  + 
Sbjct: 811 GAIEEEAKEKTS--EAPKKDEEKGKEGDSEKESEKSDGDPIVDPEKEKEPKEGQEEVLKE 868

Query: 577 NKSGSEDEMKEADESTGSGD 596
                 +   + +   G G+
Sbjct: 869 VVESEGERKTKVERDIGEGN 888



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 28/74 (37%), Positives = 42/74 (56%), Gaps = 7/74 (9%)

Query: 499 KHKDTEYKKTDICIPQTKGVLEQEEKE-EKAALEKPMDLEEEKKQNDG--EMLEKEEESE 555
           K K +E  K D    + KG     EKE EK+  +  +D E+EK+  +G  E+L++  ESE
Sbjct: 818 KEKTSEAPKKD----EEKGKEGDSEKESEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESE 873

Query: 556 PEEKSEEEIEIIEG 569
            E K++ E +I EG
Sbjct: 874 GERKTKVERDIGEG 887


>gi|21237805 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin c2 isoform a [Homo sapiens]
          Length = 1214

 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 12/101 (11%)

Query: 514 QTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEG---- 569
           + +G    E+KE K   E    +EEE K+   E  +K+EE   E  SE+E E  +G    
Sbjct: 760 RVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKESEKSDGDPIV 819

Query: 570 QEESNQSNKSGSEDEMKEADESTGSGDGPIKSVRKRRVRKD 610
             E  +  K G E+ +KE  ES G         RK +V +D
Sbjct: 820 DPEKEKEPKEGQEEVLKEVVESEGE--------RKTKVERD 852



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 23/80 (28%), Positives = 39/80 (48%), Gaps = 2/80 (2%)

Query: 517 GVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQS 576
           G +E+E KE+ +  E P   EE+ K+ D E   ++ + +P    E+E E  EGQEE  + 
Sbjct: 780 GAIEEEAKEKTS--EAPKKDEEKGKEGDSEKESEKSDGDPIVDPEKEKEPKEGQEEVLKE 837

Query: 577 NKSGSEDEMKEADESTGSGD 596
                 +   + +   G G+
Sbjct: 838 VVESEGERKTKVERDIGEGN 857



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 28/74 (37%), Positives = 42/74 (56%), Gaps = 7/74 (9%)

Query: 499 KHKDTEYKKTDICIPQTKGVLEQEEKE-EKAALEKPMDLEEEKKQNDG--EMLEKEEESE 555
           K K +E  K D    + KG     EKE EK+  +  +D E+EK+  +G  E+L++  ESE
Sbjct: 787 KEKTSEAPKKD----EEKGKEGDSEKESEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESE 842

Query: 556 PEEKSEEEIEIIEG 569
            E K++ E +I EG
Sbjct: 843 GERKTKVERDIGEG 856


>gi|194363725 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin c2 isoform c [Homo sapiens]
          Length = 1152

 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 12/101 (11%)

Query: 514 QTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEG---- 569
           + +G    E+KE K   E    +EEE K+   E  +K+EE   E  SE+E E  +G    
Sbjct: 791 RVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKESEKSDGDPIV 850

Query: 570 QEESNQSNKSGSEDEMKEADESTGSGDGPIKSVRKRRVRKD 610
             E  +  K G E+ +KE  ES G         RK +V +D
Sbjct: 851 DPEKEKEPKEGQEEVLKEVVESEGE--------RKTKVERD 883



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 23/80 (28%), Positives = 39/80 (48%), Gaps = 2/80 (2%)

Query: 517 GVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQS 576
           G +E+E KE+ +  E P   EE+ K+ D E   ++ + +P    E+E E  EGQEE  + 
Sbjct: 811 GAIEEEAKEKTS--EAPKKDEEKGKEGDSEKESEKSDGDPIVDPEKEKEPKEGQEEVLKE 868

Query: 577 NKSGSEDEMKEADESTGSGD 596
                 +   + +   G G+
Sbjct: 869 VVESEGERKTKVERDIGEGN 888



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 28/74 (37%), Positives = 42/74 (56%), Gaps = 7/74 (9%)

Query: 499 KHKDTEYKKTDICIPQTKGVLEQEEKE-EKAALEKPMDLEEEKKQNDG--EMLEKEEESE 555
           K K +E  K D    + KG     EKE EK+  +  +D E+EK+  +G  E+L++  ESE
Sbjct: 818 KEKTSEAPKKD----EEKGKEGDSEKESEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESE 873

Query: 556 PEEKSEEEIEIIEG 569
            E K++ E +I EG
Sbjct: 874 GERKTKVERDIGEG 887


>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
          Length = 709

 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 35/100 (35%), Positives = 49/100 (49%), Gaps = 14/100 (14%)

Query: 521 QEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKSG 580
           +E+ EE   +E+  + E+E+   DGE  E+EEE E EE+ EEE E    Q+E +Q  +  
Sbjct: 206 EEDVEEDEEVEEDAE-EDEEVDEDGE--EEEEEEEEEEEEEEEEEEEYEQDERDQKEEGN 262

Query: 581 SEDEMKEA-----------DESTGSGDGPIKSVRKRRVRK 609
             D   EA           D S  SG G   S  K++ RK
Sbjct: 263 DYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERK 302



 Score = 30.4 bits (67), Expect = 5.0
 Identities = 22/78 (28%), Positives = 35/78 (44%), Gaps = 8/78 (10%)

Query: 521 QEEKEEKAALEKPMDLE--------EEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEE 572
           Q  KEE  + E   D E        E+    + E    EE+ E +E+ EE+ E  E  +E
Sbjct: 168 QSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDE 227

Query: 573 SNQSNKSGSEDEMKEADE 590
             +  +   E+E +E +E
Sbjct: 228 DGEEEEEEEEEEEEEEEE 245



 Score = 30.4 bits (67), Expect = 5.0
 Identities = 17/60 (28%), Positives = 32/60 (53%)

Query: 531 EKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKSGSEDEMKEADE 590
           E+  + E E++  + ++ E EE  E  E+ EE  E  E +EE  +  +   E+E +E ++
Sbjct: 193 EQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQ 252


>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
          Length = 727

 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 35/100 (35%), Positives = 49/100 (49%), Gaps = 14/100 (14%)

Query: 521 QEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKSG 580
           +E+ EE   +E+  + E+E+   DGE  E+EEE E EE+ EEE E    Q+E +Q  +  
Sbjct: 206 EEDVEEDEEVEEDAE-EDEEVDEDGE--EEEEEEEEEEEEEEEEEEEYEQDERDQKEEGN 262

Query: 581 SEDEMKEA-----------DESTGSGDGPIKSVRKRRVRK 609
             D   EA           D S  SG G   S  K++ RK
Sbjct: 263 DYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERK 302



 Score = 30.4 bits (67), Expect = 5.0
 Identities = 22/78 (28%), Positives = 35/78 (44%), Gaps = 8/78 (10%)

Query: 521 QEEKEEKAALEKPMDLE--------EEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEE 572
           Q  KEE  + E   D E        E+    + E    EE+ E +E+ EE+ E  E  +E
Sbjct: 168 QSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDE 227

Query: 573 SNQSNKSGSEDEMKEADE 590
             +  +   E+E +E +E
Sbjct: 228 DGEEEEEEEEEEEEEEEE 245



 Score = 30.4 bits (67), Expect = 5.0
 Identities = 17/60 (28%), Positives = 32/60 (53%)

Query: 531 EKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKSGSEDEMKEADE 590
           E+  + E E++  + ++ E EE  E  E+ EE  E  E +EE  +  +   E+E +E ++
Sbjct: 193 EQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQ 252


>gi|21735415 centromere protein B [Homo sapiens]
          Length = 599

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 9/76 (11%)

Query: 520 EQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKS 579
           E EE+EE+         EEE+++ +GE  E+EEE E EE+   E E +  +EE  +    
Sbjct: 404 EGEEEEEE---------EEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDV 454

Query: 580 GSEDEMKEADESTGSG 595
            S++E +E +ES+  G
Sbjct: 455 DSDEEEEEDEESSSEG 470



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 24/65 (36%), Positives = 38/65 (58%), Gaps = 2/65 (3%)

Query: 520 EQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKS 579
           E+EE+EE+   E+  +  EE+++  GE  E  EE E EE  E +++  E +EE  +S+  
Sbjct: 412 EEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEE--EGDVDSDEEEEEDEESSSE 469

Query: 580 GSEDE 584
           G E E
Sbjct: 470 GLEAE 474



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 22/55 (40%), Positives = 32/55 (58%), Gaps = 3/55 (5%)

Query: 542 QNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKSGSEDEMKEADESTGSGD 596
           +++GE  E+EEE E EE+ E E E  EG+EE  +    G  +E+ E +E    GD
Sbjct: 402 KSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEE---GGEGEELGEEEEVEEEGD 453



 Score = 32.7 bits (73), Expect = 1.00
 Identities = 20/49 (40%), Positives = 27/49 (55%), Gaps = 2/49 (4%)

Query: 541 KQNDGEMLEKEEESEPE--EKSEEEIEIIEGQEESNQSNKSGSEDEMKE 587
           K    E  E+EEE E E  E  EEE E  E +EE  +  + G E+E++E
Sbjct: 402 KSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEE 450



 Score = 29.6 bits (65), Expect = 8.5
 Identities = 23/102 (22%), Positives = 42/102 (41%), Gaps = 25/102 (24%)

Query: 514 QTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEE---------- 563
           + +G  E+EE  E   L +  ++EEE   +  E  E++EES  E    E+          
Sbjct: 426 EEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGG 485

Query: 564 ---------------IEIIEGQEESNQSNKSGSEDEMKEADE 590
                          +  +EG E+S+  ++   ++E  + DE
Sbjct: 486 SFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDE 527


>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 35/110 (31%), Positives = 60/110 (54%), Gaps = 8/110 (7%)

Query: 497 KKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEES-- 554
           ++K ++ E K+ +    Q K + EQ+EK  +   E+ M  +EEK +   EM++ +EE   
Sbjct: 394 EEKIREQEEKRQEKMWRQEKKMREQDEKIREQ--EEEMWRQEEKIRELEEMMQDQEEKLR 451

Query: 555 EPEEKSEEEIEIIEGQEESNQSNKSGSEDEMKEADESTGSGDGPIKSVRK 604
           E EEK +EE E ++ QEE  Q      E++++E +E T   +  +K   K
Sbjct: 452 EVEEKMQEEEEKMQEQEEKIQR----QEEKIQEQEEKTWRQEKLLKQEEK 497



 Score = 38.1 bits (87), Expect = 0.024
 Identities = 32/99 (32%), Positives = 49/99 (49%), Gaps = 9/99 (9%)

Query: 494 RKVKKKHKDTEY--KKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKE 551
           R+ +K H+  E   ++ D    Q + + EQEEK  +   EK    EE+ ++ D ++ E+E
Sbjct: 329 RQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQE-EKMWRQEEKIREQDEKIQEQE 387

Query: 552 EESEPEEKSEEEIEIIEGQEESNQSNKSGSEDEMKEADE 590
           EE   +E      E I  QEE  Q      E +M+E DE
Sbjct: 388 EEMWRQE------EKIREQEEKRQEKMWRQEKKMREQDE 420



 Score = 37.4 bits (85), Expect = 0.041
 Identities = 31/126 (24%), Positives = 63/126 (50%), Gaps = 13/126 (10%)

Query: 492 WPRKVKKKHKDTEYKKTDICIPQTKGVLEQEEK---EEKAALEKPMDLEEEKKQNDGEML 548
           W ++ K + +D + ++      Q + +  QEEK   +E+   EK    E++ ++ D ++ 
Sbjct: 370 WRQEEKIREQDEKIQE------QEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIR 423

Query: 549 EKEEES-EPEEKSEEEIEIIEGQEE---SNQSNKSGSEDEMKEADESTGSGDGPIKSVRK 604
           E+EEE    EEK  E  E+++ QEE     +      E++M+E +E     +  I+   +
Sbjct: 424 EQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEE 483

Query: 605 RRVRKD 610
           +  R++
Sbjct: 484 KTWRQE 489



 Score = 36.2 bits (82), Expect = 0.090
 Identities = 33/106 (31%), Positives = 59/106 (55%), Gaps = 9/106 (8%)

Query: 494 RKVKKKHKDTEYKKTDICIPQTKGVLEQEEK----EEKAA-LEKPMDLEEEK-KQNDGEM 547
           R+ ++K ++  +++      Q + + EQEE+    EEK   LE+ M  +EEK ++ + +M
Sbjct: 398 REQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKM 457

Query: 548 LEKEEES-EPEEKSEEEIEIIEGQEES--NQSNKSGSEDEMKEADE 590
            E+EE+  E EEK + + E I+ QEE    Q      E+++ E +E
Sbjct: 458 QEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 32/106 (30%), Positives = 50/106 (47%), Gaps = 10/106 (9%)

Query: 514 QTKGVLEQEEKEEKAAL-----EKPMDLEEEKKQNDGEMLEKEEES--EPEEKSEEEIEI 566
           Q + + EQEEK  +  L     E+ M  +EEK     E + ++E+     EEK  E+ E 
Sbjct: 302 QEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEK 361

Query: 567 IEGQEES--NQSNKSGSEDE-MKEADESTGSGDGPIKSVRKRRVRK 609
           I  QEE    Q  K   +DE ++E +E     +  I+   ++R  K
Sbjct: 362 IREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEK 407



 Score = 35.0 bits (79), Expect = 0.20
 Identities = 21/81 (25%), Positives = 45/81 (55%), Gaps = 11/81 (13%)

Query: 521 QEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEES--EPEEKSEEEIEIIEGQEESNQSNK 578
           Q+++E+   +E+ M  EEEK Q   E ++++EE   E EEK+  + ++++ +E+  +  +
Sbjct: 444 QDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503

Query: 579 S---------GSEDEMKEADE 590
                       E++M+E +E
Sbjct: 504 KMWRQEEKMWEQEEKMQEQEE 524



 Score = 34.3 bits (77), Expect = 0.34
 Identities = 28/101 (27%), Positives = 51/101 (50%), Gaps = 5/101 (4%)

Query: 494 RKVKKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEE 553
           R++++  +D E K  ++     +   + +E+EEK   ++    E+E+K    E L K+EE
Sbjct: 437 RELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEE 496

Query: 554 S--EPEEKSEEEIEIIEGQEESNQSNK---SGSEDEMKEAD 589
              E EEK   + E +  QEE  Q  +      E++M+E +
Sbjct: 497 KIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQE 537



 Score = 31.6 bits (70), Expect = 2.2
 Identities = 27/109 (24%), Positives = 54/109 (49%), Gaps = 15/109 (13%)

Query: 494 RKVKKKHKDTEYK---KTDICIPQTKGVLEQEEK---EEKAALEKPMDLEEEKK------ 541
           R+V++K ++ E K   + +    Q + + EQEEK   +EK   ++    E+E+K      
Sbjct: 451 REVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEE 510

Query: 542 ---QNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKSGSEDEMKE 587
              + + +M E+EE+ + +E+   E E+   Q+E     +     E++E
Sbjct: 511 KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEE 559



 Score = 31.2 bits (69), Expect = 2.9
 Identities = 22/96 (22%), Positives = 52/96 (54%), Gaps = 1/96 (1%)

Query: 492 WPRKVKKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKE 551
           W ++ K + +D + ++ +  + + +  + + E+  +   EK  ++EE+ ++ + +M E+E
Sbjct: 409 WRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQE 468

Query: 552 EESE-PEEKSEEEIEIIEGQEESNQSNKSGSEDEMK 586
           E+ +  EEK +E+ E    QE+  +  +   E E K
Sbjct: 469 EKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEK 504



 Score = 30.0 bits (66), Expect = 6.5
 Identities = 21/78 (26%), Positives = 41/78 (52%), Gaps = 6/78 (7%)

Query: 519 LEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESE---PEEKSEEEIEIIEGQEES-- 573
           L  +++EEK   ++    E+E+K  + E+  +E+E +    EEK  E+ E I  QE+   
Sbjct: 290 LLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMW 349

Query: 574 -NQSNKSGSEDEMKEADE 590
             +      E++++E +E
Sbjct: 350 RQEEKIREQEEKIREQEE 367


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.135    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,150,102
Number of Sequences: 37866
Number of extensions: 1563473
Number of successful extensions: 23791
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 465
Number of HSP's successfully gapped in prelim test: 577
Number of HSP's that attempted gapping in prelim test: 9305
Number of HSP's gapped (non-prelim): 7600
length of query: 610
length of database: 18,247,518
effective HSP length: 108
effective length of query: 502
effective length of database: 14,157,990
effective search space: 7107310980
effective search space used: 7107310980
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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