Guide to the Human Genome
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Search of human proteins with 194354001

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194354001 solute carrier family 8 (sodium/calcium
exchanger), member 3 isoform G [Homo sapiens]
         (298 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|33946304 solute carrier family 8 (sodium/calcium exchanger), ...   603   e-173
gi|194354001 solute carrier family 8 (sodium/calcium exchanger),...   603   e-173
gi|33946311 solute carrier family 8 (sodium/calcium exchanger), ...   597   e-171
gi|17865805 solute carrier family 8 (sodium/calcium exchanger), ...   592   e-169
gi|15147254 solute carrier family 8 (sodium/calcium exchanger), ...   587   e-168
gi|33946308 solute carrier family 8 (sodium/calcium exchanger), ...   577   e-165
gi|57163987 solute carrier family 8 member 2 [Homo sapiens]           500   e-142
gi|10863913 solute carrier family 8 (sodium/calcium exchanger), ...   475   e-134
gi|163914373 solute carrier family 8 (sodium/calcium exchanger),...   475   e-134
gi|163914371 solute carrier family 8 (sodium/calcium exchanger),...   475   e-134
gi|163914369 solute carrier family 8 (sodium/calcium exchanger),...   475   e-134
gi|31563526 solute carrier family 24 (sodium/potassium/calcium e...    65   9e-11
gi|29788987 solute carrier family 24 member 4 isoform 3 [Homo sa...    60   2e-09
gi|29788985 solute carrier family 24 member 4 isoform 2 precurso...    60   2e-09
gi|24111228 solute carrier family 24 member 4 isoform 1 precurso...    60   2e-09
gi|9966787 solute carrier family 24 (sodium/potassium/calcium ex...    54   2e-07
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex...    50   2e-06
gi|45504369 solute carrier family 24, member 5 [Homo sapiens]          45   6e-05
gi|39995086 solute carrier family 24 member 6 [Homo sapiens]           34   0.14 
gi|91208428 protein tyrosine phosphatase, receptor-type, zeta1 p...    32   0.68 
gi|239752744 PREDICTED: hypothetical protein [Homo sapiens]            30   2.0  
gi|125490354 spermatogenesis associated 1 [Homo sapiens]               30   2.0  
gi|11068137 hydroxyacid oxidase 1 [Homo sapiens]                       29   4.4  
gi|157384977 glutamate receptor, ionotropic, delta 2 [Homo sapiens]    29   5.7  
gi|28557777 immunoglobulin-like domain containing receptor 1 [Ho...    29   5.7  
gi|51093836 hypothetical protein LOC126859 isoform 1 [Homo sapiens]    28   7.5  
gi|51093834 hypothetical protein LOC126859 isoform 2 [Homo sapiens]    28   7.5  
gi|55741643 kelch-like 14 [Homo sapiens]                               28   7.5  
gi|18105054 kinesin-associated protein 3 [Homo sapiens]                28   9.8  

>gi|33946304 solute carrier family 8 (sodium/calcium exchanger),
           member 3 isoform D precursor [Homo sapiens]
          Length = 921

 Score =  603 bits (1556), Expect = e-173
 Identities = 298/298 (100%), Positives = 298/298 (100%)

Query: 1   MERGISDVTDRKLTMEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKLIKKTNL 60
           MERGISDVTDRKLTMEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKLIKKTNL
Sbjct: 624 MERGISDVTDRKLTMEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKLIKKTNL 683

Query: 61  ALVVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACVPPT 120
           ALVVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACVPPT
Sbjct: 684 ALVVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACVPPT 743

Query: 121 EYCHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKA 180
           EYCHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKA
Sbjct: 744 EYCHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKA 803

Query: 181 AALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFT 240
           AALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFT
Sbjct: 804 AALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFT 863

Query: 241 IFAFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF 298
           IFAFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF
Sbjct: 864 IFAFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF 921



 Score = 31.6 bits (70), Expect = 0.88
 Identities = 21/96 (21%), Positives = 45/96 (46%), Gaps = 7/96 (7%)

Query: 158 DSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIG--NVTGSNAVNVFLGIGLAWSVAA 215
           ++V+ +  +A G+S P+   S        +    +G   + GS A N+F+ IG+      
Sbjct: 131 ETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGI-----C 185

Query: 216 IYWALQGQEFHVSAGTLAFSVTLFTIFAFVCISVLL 251
           +Y    G+   +    + F    ++IFA++ + ++L
Sbjct: 186 VYVIPDGETRKIKHLRVFFITAAWSIFAYIWLYMIL 221


>gi|194354001 solute carrier family 8 (sodium/calcium exchanger),
           member 3 isoform G [Homo sapiens]
          Length = 298

 Score =  603 bits (1556), Expect = e-173
 Identities = 298/298 (100%), Positives = 298/298 (100%)

Query: 1   MERGISDVTDRKLTMEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKLIKKTNL 60
           MERGISDVTDRKLTMEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKLIKKTNL
Sbjct: 1   MERGISDVTDRKLTMEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKLIKKTNL 60

Query: 61  ALVVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACVPPT 120
           ALVVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACVPPT
Sbjct: 61  ALVVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACVPPT 120

Query: 121 EYCHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKA 180
           EYCHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKA
Sbjct: 121 EYCHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKA 180

Query: 181 AALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFT 240
           AALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFT
Sbjct: 181 AALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFT 240

Query: 241 IFAFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF 298
           IFAFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF
Sbjct: 241 IFAFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF 298


>gi|33946311 solute carrier family 8 (sodium/calcium exchanger),
           member 3 isoform C precursor [Homo sapiens]
          Length = 927

 Score =  597 bits (1539), Expect = e-171
 Identities = 298/304 (98%), Positives = 298/304 (98%), Gaps = 6/304 (1%)

Query: 1   MERGIS------DVTDRKLTMEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKL 54
           MERGIS      DVTDRKLTMEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKL
Sbjct: 624 MERGISALLLSPDVTDRKLTMEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKL 683

Query: 55  IKKTNLALVVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLF 114
           IKKTNLALVVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLF
Sbjct: 684 IKKTNLALVVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLF 743

Query: 115 ACVPPTEYCHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPD 174
           ACVPPTEYCHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPD
Sbjct: 744 ACVPPTEYCHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPD 803

Query: 175 TFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAF 234
           TFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAF
Sbjct: 804 TFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAF 863

Query: 235 SVTLFTIFAFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCY 294
           SVTLFTIFAFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCY
Sbjct: 864 SVTLFTIFAFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCY 923

Query: 295 IKGF 298
           IKGF
Sbjct: 924 IKGF 927



 Score = 31.6 bits (70), Expect = 0.88
 Identities = 21/96 (21%), Positives = 45/96 (46%), Gaps = 7/96 (7%)

Query: 158 DSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIG--NVTGSNAVNVFLGIGLAWSVAA 215
           ++V+ +  +A G+S P+   S        +    +G   + GS A N+F+ IG+      
Sbjct: 131 ETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGI-----C 185

Query: 216 IYWALQGQEFHVSAGTLAFSVTLFTIFAFVCISVLL 251
           +Y    G+   +    + F    ++IFA++ + ++L
Sbjct: 186 VYVIPDGETRKIKHLRVFFITAAWSIFAYIWLYMIL 221


>gi|17865805 solute carrier family 8 (sodium/calcium exchanger),
           member 3 isoform B precursor [Homo sapiens]
          Length = 924

 Score =  592 bits (1525), Expect = e-169
 Identities = 295/301 (98%), Positives = 296/301 (98%), Gaps = 3/301 (0%)

Query: 1   MERGISDVT---DRKLTMEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKLIKK 57
           MERGIS +    DRKLTMEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKLIKK
Sbjct: 624 MERGISALLLSPDRKLTMEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKLIKK 683

Query: 58  TNLALVVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACV 117
           TNLALVVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACV
Sbjct: 684 TNLALVVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACV 743

Query: 118 PPTEYCHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFA 177
           PPTEYCHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFA
Sbjct: 744 PPTEYCHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFA 803

Query: 178 SKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVT 237
           SKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVT
Sbjct: 804 SKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVT 863

Query: 238 LFTIFAFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKG 297
           LFTIFAFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKG
Sbjct: 864 LFTIFAFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKG 923

Query: 298 F 298
           F
Sbjct: 924 F 924



 Score = 31.6 bits (70), Expect = 0.88
 Identities = 21/96 (21%), Positives = 45/96 (46%), Gaps = 7/96 (7%)

Query: 158 DSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIG--NVTGSNAVNVFLGIGLAWSVAA 215
           ++V+ +  +A G+S P+   S        +    +G   + GS A N+F+ IG+      
Sbjct: 131 ETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGI-----C 185

Query: 216 IYWALQGQEFHVSAGTLAFSVTLFTIFAFVCISVLL 251
           +Y    G+   +    + F    ++IFA++ + ++L
Sbjct: 186 VYVIPDGETRKIKHLRVFFITAAWSIFAYIWLYMIL 221


>gi|15147254 solute carrier family 8 (sodium/calcium exchanger),
           member 3 isoform A precursor [Homo sapiens]
          Length = 925

 Score =  587 bits (1512), Expect = e-168
 Identities = 289/289 (100%), Positives = 289/289 (100%)

Query: 10  DRKLTMEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKLIKKTNLALVVGTHSW 69
           DRKLTMEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKLIKKTNLALVVGTHSW
Sbjct: 637 DRKLTMEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKLIKKTNLALVVGTHSW 696

Query: 70  RDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACVPPTEYCHGWACF 129
           RDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACVPPTEYCHGWACF
Sbjct: 697 RDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACVPPTEYCHGWACF 756

Query: 130 AVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYAD 189
           AVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYAD
Sbjct: 757 AVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYAD 816

Query: 190 ASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCISV 249
           ASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCISV
Sbjct: 817 ASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCISV 876

Query: 250 LLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF 298
           LLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF
Sbjct: 877 LLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF 925



 Score = 31.6 bits (70), Expect = 0.88
 Identities = 21/96 (21%), Positives = 45/96 (46%), Gaps = 7/96 (7%)

Query: 158 DSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIG--NVTGSNAVNVFLGIGLAWSVAA 215
           ++V+ +  +A G+S P+   S        +    +G   + GS A N+F+ IG+      
Sbjct: 131 ETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGI-----C 185

Query: 216 IYWALQGQEFHVSAGTLAFSVTLFTIFAFVCISVLL 251
           +Y    G+   +    + F    ++IFA++ + ++L
Sbjct: 186 VYVIPDGETRKIKHLRVFFITAAWSIFAYIWLYMIL 221


>gi|33946308 solute carrier family 8 (sodium/calcium exchanger),
           member 3 isoform F [Homo sapiens]
          Length = 284

 Score =  577 bits (1487), Expect = e-165
 Identities = 284/284 (100%), Positives = 284/284 (100%)

Query: 15  MEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKLIKKTNLALVVGTHSWRDQFM 74
           MEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKLIKKTNLALVVGTHSWRDQFM
Sbjct: 1   MEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKLIKKTNLALVVGTHSWRDQFM 60

Query: 75  EAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACVPPTEYCHGWACFAVSIL 134
           EAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACVPPTEYCHGWACFAVSIL
Sbjct: 61  EAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACVPPTEYCHGWACFAVSIL 120

Query: 135 IIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGN 194
           IIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGN
Sbjct: 121 IIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGN 180

Query: 195 VTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCISVLLYRR 254
           VTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCISVLLYRR
Sbjct: 181 VTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCISVLLYRR 240

Query: 255 RPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF 298
           RPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF
Sbjct: 241 RPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF 284


>gi|57163987 solute carrier family 8 member 2 [Homo sapiens]
          Length = 921

 Score =  500 bits (1288), Expect = e-142
 Identities = 248/306 (81%), Positives = 277/306 (90%), Gaps = 9/306 (2%)

Query: 1   MERGISDVT------DRKLTMEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKL 54
           ++RGIS +       DRKLT EEEEA+RIAEMGKPVLGE+ +LEVIIEESY+FK TVDKL
Sbjct: 617 LKRGISALLLNQGDGDRKLTAEEEEARRIAEMGKPVLGENCRLEVIIEESYDFKNTVDKL 676

Query: 55  IKKTNLALVVGTHSWRDQFMEAITVSAAGDEDEDESG--EERLPSCFDYVMHFLTVFWKV 112
           IKKTNLALV+GTHSWR+QF+EAITVSA GDE+E+E G  EERLPSCFDYVMHFLTVFWKV
Sbjct: 677 IKKTNLALVIGTHSWREQFLEAITVSA-GDEEEEEDGSREERLPSCFDYVMHFLTVFWKV 735

Query: 113 LFACVPPTEYCHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSV 172
           LFACVPPTEYCHGWACF VSIL+IG+LTA+IGDLASHFGCT+GLKDSV AVVFVA GTS+
Sbjct: 736 LFACVPPTEYCHGWACFGVSILVIGLLTALIGDLASHFGCTVGLKDSVNAVVFVALGTSI 795

Query: 173 PDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTL 232
           PDTFASK AALQD  ADASIGNVTGSNAVNVFLG+G+AWSVAA+YWA+QG+ F V  GTL
Sbjct: 796 PDTFASKVAALQDQCADASIGNVTGSNAVNVFLGLGVAWSVAAVYWAVQGRPFEVRTGTL 855

Query: 233 AFSVTLFTIFAFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAY 292
           AFSVTLFT+FAFV I+VLLYRRRPH+GGELGGPRG KLATT LF+ LWLLYILFA+LEAY
Sbjct: 856 AFSVTLFTVFAFVGIAVLLYRRRPHIGGELGGPRGPKLATTALFLGLWLLYILFASLEAY 915

Query: 293 CYIKGF 298
           C+I+GF
Sbjct: 916 CHIRGF 921


>gi|10863913 solute carrier family 8 (sodium/calcium exchanger),
           member 1 isoform A [Homo sapiens]
          Length = 973

 Score =  475 bits (1223), Expect = e-134
 Identities = 237/296 (80%), Positives = 263/296 (88%), Gaps = 2/296 (0%)

Query: 5   ISDVTDRK--LTMEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKLIKKTNLAL 62
           I+D  D K  LT +EEE +RIAEMG+P+LGEH KLEVIIEESYEFK+TVDKLIKKTNLAL
Sbjct: 678 IADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKTNLAL 737

Query: 63  VVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACVPPTEY 122
           VVGT+SWR+QF+EAITVSA  D+D+DE GEE+LPSCFDYVMHFLTVFWKVLFA VPPTEY
Sbjct: 738 VVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTEY 797

Query: 123 CHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAA 182
            +GWACF VSIL+IG+LTA IGDLASHFGCTIGLKDSVTAVVFVA GTSVPDTFASK AA
Sbjct: 798 WNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAA 857

Query: 183 LQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIF 242
            QD YADASIGNVTGSNAVNVFLGIG+AWS+AAIY A  G++F VS GTLAFSVTLFTIF
Sbjct: 858 TQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIF 917

Query: 243 AFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF 298
           AF+ + VLLYRRRP +GGELGGPR  KL T+ LFV LWLLYI F++LEAYC+IKGF
Sbjct: 918 AFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIFFSSLEAYCHIKGF 973


>gi|163914373 solute carrier family 8 (sodium/calcium exchanger),
           member 1 isoform D [Homo sapiens]
          Length = 937

 Score =  475 bits (1223), Expect = e-134
 Identities = 237/296 (80%), Positives = 263/296 (88%), Gaps = 2/296 (0%)

Query: 5   ISDVTDRK--LTMEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKLIKKTNLAL 62
           I+D  D K  LT +EEE +RIAEMG+P+LGEH KLEVIIEESYEFK+TVDKLIKKTNLAL
Sbjct: 642 ITDEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKTNLAL 701

Query: 63  VVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACVPPTEY 122
           VVGT+SWR+QF+EAITVSA  D+D+DE GEE+LPSCFDYVMHFLTVFWKVLFA VPPTEY
Sbjct: 702 VVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTEY 761

Query: 123 CHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAA 182
            +GWACF VSIL+IG+LTA IGDLASHFGCTIGLKDSVTAVVFVA GTSVPDTFASK AA
Sbjct: 762 WNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAA 821

Query: 183 LQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIF 242
            QD YADASIGNVTGSNAVNVFLGIG+AWS+AAIY A  G++F VS GTLAFSVTLFTIF
Sbjct: 822 TQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIF 881

Query: 243 AFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF 298
           AF+ + VLLYRRRP +GGELGGPR  KL T+ LFV LWLLYI F++LEAYC+IKGF
Sbjct: 882 AFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIFFSSLEAYCHIKGF 937


>gi|163914371 solute carrier family 8 (sodium/calcium exchanger),
           member 1 isoform C [Homo sapiens]
          Length = 960

 Score =  475 bits (1223), Expect = e-134
 Identities = 237/296 (80%), Positives = 263/296 (88%), Gaps = 2/296 (0%)

Query: 5   ISDVTDRK--LTMEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKLIKKTNLAL 62
           I+D  D K  LT +EEE +RIAEMG+P+LGEH KLEVIIEESYEFK+TVDKLIKKTNLAL
Sbjct: 665 IADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKTNLAL 724

Query: 63  VVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACVPPTEY 122
           VVGT+SWR+QF+EAITVSA  D+D+DE GEE+LPSCFDYVMHFLTVFWKVLFA VPPTEY
Sbjct: 725 VVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTEY 784

Query: 123 CHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAA 182
            +GWACF VSIL+IG+LTA IGDLASHFGCTIGLKDSVTAVVFVA GTSVPDTFASK AA
Sbjct: 785 WNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAA 844

Query: 183 LQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIF 242
            QD YADASIGNVTGSNAVNVFLGIG+AWS+AAIY A  G++F VS GTLAFSVTLFTIF
Sbjct: 845 TQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIF 904

Query: 243 AFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF 298
           AF+ + VLLYRRRP +GGELGGPR  KL T+ LFV LWLLYI F++LEAYC+IKGF
Sbjct: 905 AFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIFFSSLEAYCHIKGF 960


>gi|163914369 solute carrier family 8 (sodium/calcium exchanger),
           member 1 isoform B [Homo sapiens]
          Length = 968

 Score =  475 bits (1223), Expect = e-134
 Identities = 237/296 (80%), Positives = 263/296 (88%), Gaps = 2/296 (0%)

Query: 5   ISDVTDRK--LTMEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKLIKKTNLAL 62
           I+D  D K  LT +EEE +RIAEMG+P+LGEH KLEVIIEESYEFK+TVDKLIKKTNLAL
Sbjct: 673 IADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKTNLAL 732

Query: 63  VVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACVPPTEY 122
           VVGT+SWR+QF+EAITVSA  D+D+DE GEE+LPSCFDYVMHFLTVFWKVLFA VPPTEY
Sbjct: 733 VVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTEY 792

Query: 123 CHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAA 182
            +GWACF VSIL+IG+LTA IGDLASHFGCTIGLKDSVTAVVFVA GTSVPDTFASK AA
Sbjct: 793 WNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAA 852

Query: 183 LQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIF 242
            QD YADASIGNVTGSNAVNVFLGIG+AWS+AAIY A  G++F VS GTLAFSVTLFTIF
Sbjct: 853 TQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIF 912

Query: 243 AFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF 298
           AF+ + VLLYRRRP +GGELGGPR  KL T+ LFV LWLLYI F++LEAYC+IKGF
Sbjct: 913 AFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIFFSSLEAYCHIKGF 968


>gi|31563526 solute carrier family 24 (sodium/potassium/calcium
           exchanger), member 3 [Homo sapiens]
          Length = 644

 Score = 64.7 bits (156), Expect = 9e-11
 Identities = 53/176 (30%), Positives = 83/176 (47%), Gaps = 14/176 (7%)

Query: 84  DEDEDESGEERLPSCFDYVMHFL-TVFWK-------VLFACVP----PTEYCHGWACFAV 131
           +E+EDE  +E   + FD     L TV W        VL+  VP    P         FA 
Sbjct: 423 EEEEDEDDDEGPYTPFDTPSGKLETVKWAFTWPLSFVLYFTVPNCNKPRWEKWFMVTFAS 482

Query: 132 SILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADAS 191
           S L I   + ++  + +  G T+G+ D +  + F+A GTSVPD  AS   A Q +  D +
Sbjct: 483 STLWIAAFSYMMVWMVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGM-GDMA 541

Query: 192 IGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCI 247
           + N  GSN  ++ +G+GL W++  +     G    +++  L +SV L     FV +
Sbjct: 542 VSNSIGSNVFDILIGLGLPWALQTLA-VDYGSYIRLNSRGLIYSVGLLLASVFVTV 596



 Score = 33.1 bits (74), Expect = 0.30
 Identities = 22/89 (24%), Positives = 36/89 (40%), Gaps = 6/89 (6%)

Query: 156 LKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGL-----A 210
           L + V    F+A G+S P+ F S    +     D  +G + GS   N+   IG+      
Sbjct: 145 LSEDVAGATFMAAGSSAPELFTS-VIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAG 203

Query: 211 WSVAAIYWALQGQEFHVSAGTLAFSVTLF 239
             VA   W L     + +   +A  V ++
Sbjct: 204 QVVALSSWCLLRDSIYYTLSVIALIVFIY 232


>gi|29788987 solute carrier family 24 member 4 isoform 3 [Homo
           sapiens]
          Length = 558

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 37/122 (30%), Positives = 64/122 (52%), Gaps = 4/122 (3%)

Query: 129 FAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYA 188
           F  + L I + + I+  L +  G T+G+ D +  + F+A GTSVPD  AS   A Q +  
Sbjct: 393 FITATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGL-G 451

Query: 189 DASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCIS 248
           D ++ N  GSN  ++ +G+G+ W +  +     G    +++  L +SV L  +   V ++
Sbjct: 452 DMAVSNTIGSNVFDILVGLGVPWGLQTMV-VNYGSTVKINSRGLVYSVVL--LLGSVALT 508

Query: 249 VL 250
           VL
Sbjct: 509 VL 510



 Score = 35.4 bits (80), Expect = 0.061
 Identities = 22/94 (23%), Positives = 43/94 (45%), Gaps = 11/94 (11%)

Query: 156 LKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGL----AW 211
           L + V    F+A G+S P+ FAS    +   + D  +G + GS   N+   IG+    A 
Sbjct: 71  LSEDVAGATFMAAGSSTPELFAS-VIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAG 129

Query: 212 SVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFV 245
            V  + W      + V   ++ +++++  +  F+
Sbjct: 130 QVVRLTW------WAVCRDSVYYTISVIVLIVFI 157


>gi|29788985 solute carrier family 24 member 4 isoform 2 precursor
           [Homo sapiens]
          Length = 586

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 37/122 (30%), Positives = 64/122 (52%), Gaps = 4/122 (3%)

Query: 129 FAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYA 188
           F  + L I + + I+  L +  G T+G+ D +  + F+A GTSVPD  AS   A Q +  
Sbjct: 421 FITATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGL-G 479

Query: 189 DASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCIS 248
           D ++ N  GSN  ++ +G+G+ W +  +     G    +++  L +SV L  +   V ++
Sbjct: 480 DMAVSNTIGSNVFDILVGLGVPWGLQTMV-VNYGSTVKINSRGLVYSVVL--LLGSVALT 536

Query: 249 VL 250
           VL
Sbjct: 537 VL 538



 Score = 35.4 bits (80), Expect = 0.061
 Identities = 22/94 (23%), Positives = 43/94 (45%), Gaps = 11/94 (11%)

Query: 156 LKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGL----AW 211
           L + V    F+A G+S P+ FAS    +   + D  +G + GS   N+   IG+    A 
Sbjct: 118 LSEDVAGATFMAAGSSTPELFAS-VIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAG 176

Query: 212 SVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFV 245
            V  + W      + V   ++ +++++  +  F+
Sbjct: 177 QVVRLTW------WAVCRDSVYYTISVIVLIVFI 204


>gi|24111228 solute carrier family 24 member 4 isoform 1 precursor
           [Homo sapiens]
          Length = 605

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 37/122 (30%), Positives = 64/122 (52%), Gaps = 4/122 (3%)

Query: 129 FAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYA 188
           F  + L I + + I+  L +  G T+G+ D +  + F+A GTSVPD  AS   A Q +  
Sbjct: 440 FITATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGL-G 498

Query: 189 DASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCIS 248
           D ++ N  GSN  ++ +G+G+ W +  +     G    +++  L +SV L  +   V ++
Sbjct: 499 DMAVSNTIGSNVFDILVGLGVPWGLQTMV-VNYGSTVKINSRGLVYSVVL--LLGSVALT 555

Query: 249 VL 250
           VL
Sbjct: 556 VL 557



 Score = 35.4 bits (80), Expect = 0.061
 Identities = 22/94 (23%), Positives = 43/94 (45%), Gaps = 11/94 (11%)

Query: 156 LKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGL----AW 211
           L + V    F+A G+S P+ FAS    +   + D  +G + GS   N+   IG+    A 
Sbjct: 118 LSEDVAGATFMAAGSSTPELFAS-VIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAG 176

Query: 212 SVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFV 245
            V  + W      + V   ++ +++++  +  F+
Sbjct: 177 QVVRLTW------WAVCRDSVYYTISVIVLIVFI 204


>gi|9966787 solute carrier family 24 (sodium/potassium/calcium
           exchanger), member 2 [Homo sapiens]
          Length = 661

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 48/178 (26%), Positives = 77/178 (43%), Gaps = 8/178 (4%)

Query: 84  DEDEDESGEERLPSCFDYVMHFLTVF------WKVLFACVPPTEYCHGWACFAVSILIIG 137
           DE+ED+      PS     + FL VF      W  L     P+        F  SI  I 
Sbjct: 452 DEEEDQPLSLAWPSETRKQVTFLIVFPIVFPLWITLPDVRKPSSRKFFPITFFGSITWIA 511

Query: 138 MLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTG 197
           + + ++   A   G TIG+ + +  +  +A GTS+PD   S   A + +  D ++ +  G
Sbjct: 512 VFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGL-GDMAVSSSVG 570

Query: 198 SNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCISVLLYRRR 255
           SN  ++ +G+ L W +  +    Q      S G     V LF +  FV +S+ L + R
Sbjct: 571 SNIFDITVGLPLPWLLYTVIHRFQPVAVS-SNGLFCAIVLLFIMLLFVILSIALCKWR 627



 Score = 35.0 bits (79), Expect = 0.080
 Identities = 17/56 (30%), Positives = 27/56 (48%), Gaps = 1/56 (1%)

Query: 154 IGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGL 209
           +G+ D V    F+A G S P+ F S        +++  IG + GS   N+   IG+
Sbjct: 168 LGISDDVAGATFMAAGGSAPELFTSLIGVF-IAHSNVGIGTIVGSAVFNILFVIGM 222


>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
            exchanger), member 1 [Homo sapiens]
          Length = 1099

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 46/178 (25%), Positives = 77/178 (43%), Gaps = 15/178 (8%)

Query: 84   DEDEDESGEERLPSCFDY--------VMHFLTVFWKVLFACVPPTEYCHGWACFAV---- 131
            +E+E+E G E  P   D+        +  FL      L+  VP          F      
Sbjct: 885  EEEEEEKGNEE-PLSLDWPETRQKQAIYLFLLPIVFPLWLTVPDVRRQESRKFFVFTFLG 943

Query: 132  SILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADAS 191
            SI+ I M + ++   A   G TIG+ + +  +  +A GTS+PD   S   A + +  D +
Sbjct: 944  SIMWIAMFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGL-GDMA 1002

Query: 192  IGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCISV 249
            + +  GSN  ++ +G+ + W + ++   LQ      S G     V LF +  FV  S+
Sbjct: 1003 VSSSVGSNIFDITVGLPVPWLLFSLINGLQPVPVS-SNGLFCAIVLLFLMLLFVISSI 1059



 Score = 29.6 bits (65), Expect = 3.4
 Identities = 15/53 (28%), Positives = 24/53 (45%), Gaps = 1/53 (1%)

Query: 156 LKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIG 208
           + + V    F+A G S P+ F S        +++  IG + GS   N+   IG
Sbjct: 490 ISEDVAGATFMAAGGSAPELFTSLIGVFIS-HSNVGIGTIVGSAVFNILFVIG 541


>gi|45504369 solute carrier family 24, member 5 [Homo sapiens]
          Length = 500

 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 31/109 (28%), Positives = 52/109 (47%), Gaps = 13/109 (11%)

Query: 109 FWKVLFACVPPTEYCHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAF 168
           FWK  F              F +S + I   T I+  + +  G T+ + D+V  +  +A 
Sbjct: 329 FWKNYFVIT-----------FFMSAIWISAFTYILVWMVTITGETLEIPDTVMGLTLLAA 377

Query: 169 GTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIY 217
           GTS+PDT AS   A +    D ++ N+ GSN  ++ L +G+ W +   +
Sbjct: 378 GTSIPDTIASVLVARKG-KGDMAMSNIVGSNVFDM-LCLGIPWFIKTAF 424


>gi|39995086 solute carrier family 24 member 6 [Homo sapiens]
          Length = 584

 Score = 34.3 bits (77), Expect = 0.14
 Identities = 37/164 (22%), Positives = 67/164 (40%), Gaps = 30/164 (18%)

Query: 139 LTAIIGDLASHFGC--------TIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADA 190
           L  I+G  A+ F C        T+ L  +V  V F+AFG   PD F++  A      A  
Sbjct: 110 LFLILGVTAAKFFCPNLSAISTTLKLSHNVAGVTFLAFGNGAPDIFSALVAFSDPHTAGL 169

Query: 191 SIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCISVL 250
           ++G + G+    V +   +A  +  ++         ++A    F   +F + A     ++
Sbjct: 170 ALGALFGA---GVLVTTVVAGGITILH-------PFMAASRPFFRDIVFYMVAVFLTFLM 219

Query: 251 LYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCY 294
           L+R R  L   LG            ++ L++ Y++   L  + Y
Sbjct: 220 LFRGRVTLAWALG------------YLGLYVFYVVTVILCTWIY 251



 Score = 32.0 bits (71), Expect = 0.68
 Identities = 21/92 (22%), Positives = 37/92 (40%), Gaps = 1/92 (1%)

Query: 118 PPTEYCHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFA 177
           P   +   +  F  S L I      + ++    G    L ++V  +  +A+G S+ D F+
Sbjct: 415 PRLHWLFAFLGFLTSALWINAAATEVVNILRSLGVVFRLSNTVLGLTLLAWGNSIGDAFS 474

Query: 178 SKAAALQDVYADASIGNVTGSNAVNVFLGIGL 209
               A Q  Y   +     G    N+ +G+GL
Sbjct: 475 DFTLARQG-YPRMAFSACFGGIIFNILVGVGL 505


>gi|91208428 protein tyrosine phosphatase, receptor-type, zeta1
            precursor [Homo sapiens]
          Length = 2315

 Score = 32.0 bits (71), Expect = 0.68
 Identities = 40/162 (24%), Positives = 63/162 (38%), Gaps = 17/162 (10%)

Query: 29   PVLGEHPKLEVIIEESYEF----KTTVDKLIKKTNLAL--VVGTHSWRDQFMEAITVSAA 82
            P+L E PK++ I             + + ++  T++ +  V  T       ++ +T+S A
Sbjct: 1206 PILVETPKVDKISSTMLHLIVSNSASSENMLHSTSVPVFDVSPTSHMHSASLQGLTISYA 1265

Query: 83   GDEDE-----DESGEERLPSCFDYVMHFLTVFWKVLFACVPPTEYCHGWACFAVSILIIG 137
             ++ E      ES  + +PS +     F T   ++  A  P      G   FA  +L I 
Sbjct: 1266 SEKYEPVLLKSESSHQVVPSLYSNDELFQTANLEINQAHPPK-----GRHVFATPVLSID 1320

Query: 138  M-LTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFAS 178
              L  +I  L          K SVT  VF    T   DTF S
Sbjct: 1321 EPLNTLINKLIHSDEILTSTKSSVTGKVFAGIPTVASDTFVS 1362


>gi|239752744 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 361

 Score = 30.4 bits (67), Expect = 2.0
 Identities = 34/142 (23%), Positives = 54/142 (38%), Gaps = 11/142 (7%)

Query: 103 MHFLTVFWKVLFACVPPTEYCHGWACFAVSILIIGMLTAIIGDLASH--FGCTIGLKDS- 159
           MH+   FW  L +  P  E C  +A        +G+     G  A+H  + C     DS 
Sbjct: 86  MHWNDAFWPALTSTSPRREKCGAFAAGLELHRELGLHPLQAGAAAAHTPYPCAPKSADSQ 145

Query: 160 VTAVVFVAFGTS-VPDTFASKAAALQDVYADA-------SIGNVTGSNAVNVFLGIGLAW 211
           ++ V   A G+S +P + A  A     V A         ++  V   + V + L   L  
Sbjct: 146 LSLVPLTAVGSSHIPHSTAQGAPINAHVDAQGARAVPVPAVQEVAELHTVGIILAQALED 205

Query: 212 SVAAIYWALQGQEFHVSAGTLA 233
            + ++ W + G   H     LA
Sbjct: 206 DMGSLAWGMLGSVDHQGGFALA 227


>gi|125490354 spermatogenesis associated 1 [Homo sapiens]
          Length = 459

 Score = 30.4 bits (67), Expect = 2.0
 Identities = 24/80 (30%), Positives = 40/80 (50%), Gaps = 5/80 (6%)

Query: 6   SDVTDRKLTMEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKLIKKTNLALVVG 65
           S +TD  L   E E  +I +  K V  E   LE   EE  +   TV+KL +++ L     
Sbjct: 284 SGITDISLLQTERE--KIIKQMKQVKEERRYLERNREELVK---TVEKLFEQSKLKRYHA 338

Query: 66  THSWRDQFMEAITVSAAGDE 85
            + W+ +++E   V+A+ +E
Sbjct: 339 YNGWKKKYLETKKVTASMEE 358


>gi|11068137 hydroxyacid oxidase 1 [Homo sapiens]
          Length = 370

 Score = 29.3 bits (64), Expect = 4.4
 Identities = 11/36 (30%), Positives = 18/36 (50%)

Query: 245 VCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLW 280
           +C+     +R  H+ GEL   R C+   T + +S W
Sbjct: 75  ICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSW 110


>gi|157384977 glutamate receptor, ionotropic, delta 2 [Homo sapiens]
          Length = 1007

 Score = 28.9 bits (63), Expect = 5.7
 Identities = 11/31 (35%), Positives = 21/31 (67%), Gaps = 1/31 (3%)

Query: 113 LFACVPPTEYCHGWACFAVSILIIGMLTAII 143
           +FAC+ P +    WAC A ++L++G+L  ++
Sbjct: 558 MFACLAPFDLSL-WACIAGTVLLVGLLVYLL 587


>gi|28557777 immunoglobulin-like domain containing receptor 1 [Homo
           sapiens]
          Length = 502

 Score = 28.9 bits (63), Expect = 5.7
 Identities = 19/63 (30%), Positives = 29/63 (46%), Gaps = 5/63 (7%)

Query: 53  KLIKKTNLALVVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKV 112
           K+  +    LV+    W D  +   T+ A GD   D   E +L      V+H+LTV + +
Sbjct: 121 KITIQNRADLVINEVMWWDHGVYYCTIEAPGDTSGDPDKEVKL-----IVLHWLTVIFII 175

Query: 113 LFA 115
           L A
Sbjct: 176 LGA 178


>gi|51093836 hypothetical protein LOC126859 isoform 1 [Homo sapiens]
          Length = 1012

 Score = 28.5 bits (62), Expect = 7.5
 Identities = 13/53 (24%), Positives = 32/53 (60%)

Query: 5   ISDVTDRKLTMEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKLIKK 57
           +S V +R + M ++ A+++ +  K ++ +    + I+EE Y FK  +++L ++
Sbjct: 284 LSKVRERYVQMLDQIARQMIDFYKDLVTQRVMDQRILEELYNFKHVIEELTRE 336


>gi|51093834 hypothetical protein LOC126859 isoform 2 [Homo sapiens]
          Length = 938

 Score = 28.5 bits (62), Expect = 7.5
 Identities = 13/53 (24%), Positives = 32/53 (60%)

Query: 5   ISDVTDRKLTMEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKLIKK 57
           +S V +R + M ++ A+++ +  K ++ +    + I+EE Y FK  +++L ++
Sbjct: 284 LSKVRERYVQMLDQIARQMIDFYKDLVTQRVMDQRILEELYNFKHVIEELTRE 336


>gi|55741643 kelch-like 14 [Homo sapiens]
          Length = 628

 Score = 28.5 bits (62), Expect = 7.5
 Identities = 21/73 (28%), Positives = 29/73 (39%), Gaps = 12/73 (16%)

Query: 198 SNAVNVFLGIGLAWS---VAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCISVLLYRR 254
           S++ N+  G+ L W       +    QGQ+FH     LA     F           L+  
Sbjct: 14  SHSDNLLHGLNLLWRKQLFCDVTLTAQGQQFHCHKAVLASCSQYFRS---------LFSS 64

Query: 255 RPHLGGELGGPRG 267
            P LGG +GG  G
Sbjct: 65  HPPLGGGVGGQDG 77


>gi|18105054 kinesin-associated protein 3 [Homo sapiens]
          Length = 792

 Score = 28.1 bits (61), Expect = 9.8
 Identities = 16/42 (38%), Positives = 23/42 (54%), Gaps = 1/42 (2%)

Query: 17 EEEAKRIAEMGKPVLGEHPKLEVIIE-ESYEFKTTVDKLIKK 57
          E EA  + EMG P+LGE  + + II  +S    T +  L +K
Sbjct: 32 EVEATILGEMGDPMLGERKECQKIIRLKSLNANTDITSLARK 73


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.138    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,748,716
Number of Sequences: 37866
Number of extensions: 439785
Number of successful extensions: 1768
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1725
Number of HSP's gapped (non-prelim): 42
length of query: 298
length of database: 18,247,518
effective HSP length: 102
effective length of query: 196
effective length of database: 14,385,186
effective search space: 2819496456
effective search space used: 2819496456
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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