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Search of human proteins with 194306651
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|194306651 pyruvate dehydrogenase phosphatase regulatory
subunit [Homo sapiens]
(879 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|194306651 pyruvate dehydrogenase phosphatase regulatory subun... 1800 0.0
gi|197927446 sarcosine dehydrogenase precursor [Homo sapiens] 429 e-120
gi|21361378 sarcosine dehydrogenase precursor [Homo sapiens] 429 e-120
gi|24797151 dimethylglycine dehydrogenase precursor [Homo sapiens] 363 e-100
gi|60499001 pipecolic acid oxidase [Homo sapiens] 62 3e-09
gi|44662838 aminomethyltransferase [Homo sapiens] 61 4e-09
gi|8923708 FAD-dependent oxidoreductase domain containing 1 [Hom... 57 8e-08
gi|13376331 L-2-hydroxyglutarate dehydrogenase precursor [Homo s... 47 6e-05
gi|28559080 spermine oxidase isoform 4 [Homo sapiens] 32 3.4
gi|28559078 spermine oxidase isoform 3 [Homo sapiens] 32 3.4
gi|28559076 spermine oxidase isoform 2 [Homo sapiens] 32 3.4
gi|28559074 spermine oxidase isoform 1 [Homo sapiens] 32 3.4
gi|218083730 zinc finger protein 237 isoform 3 [Homo sapiens] 32 3.4
gi|32967305 coenzyme Q6 homolog isoform a [Homo sapiens] 32 3.4
gi|239756515 PREDICTED: similar to Putative 3-beta-HSD family pr... 31 4.4
gi|239751020 PREDICTED: hypothetical protein XP_002347673 [Homo ... 31 4.4
gi|239745448 PREDICTED: hypothetical protein XP_002343493 [Homo ... 31 4.4
gi|170650615 protoporphyrinogen oxidase [Homo sapiens] 31 4.4
gi|4506001 protoporphyrinogen oxidase [Homo sapiens] 31 4.4
gi|223005862 echinoderm microtubule associated protein like 6 [H... 31 5.8
gi|13346498 WW domain containing transcription regulator 1 [Homo... 30 7.5
gi|239743164 PREDICTED: hypothetical protein [Homo sapiens] 30 9.8
gi|239508826 PREDICTED: hypothetical protein [Homo sapiens] 30 9.8
gi|52218858 olfactory receptor, family 13, subfamily F, member 1... 30 9.8
>gi|194306651 pyruvate dehydrogenase phosphatase regulatory subunit
[Homo sapiens]
Length = 879
Score = 1800 bits (4661), Expect = 0.0
Identities = 879/879 (100%), Positives = 879/879 (100%)
Query: 1 MMFYRLLSIVGRQRASPGWQNWSSARNSTSAAEARSMALPTQAQVVICGGGITGTSVAYH 60
MMFYRLLSIVGRQRASPGWQNWSSARNSTSAAEARSMALPTQAQVVICGGGITGTSVAYH
Sbjct: 1 MMFYRLLSIVGRQRASPGWQNWSSARNSTSAAEARSMALPTQAQVVICGGGITGTSVAYH 60
Query: 61 LSKMGWKDIVLLEQGRLAAGSTRFCAGILSTARHLTIEQKMADYSNKLYYQLEQETGIQT 120
LSKMGWKDIVLLEQGRLAAGSTRFCAGILSTARHLTIEQKMADYSNKLYYQLEQETGIQT
Sbjct: 61 LSKMGWKDIVLLEQGRLAAGSTRFCAGILSTARHLTIEQKMADYSNKLYYQLEQETGIQT 120
Query: 121 GYTRTGSIFLAQTQDRLISLKRINAGLNVIGIPSEIISPKKVAELHHLLNVHDLVGAMHV 180
GYTRTGSIFLAQTQDRLISLKRINAGLNVIGIPSEIISPKKVAELHHLLNVHDLVGAMHV
Sbjct: 121 GYTRTGSIFLAQTQDRLISLKRINAGLNVIGIPSEIISPKKVAELHHLLNVHDLVGAMHV 180
Query: 181 PEDAVVSSADVALALASAASQNGVQIYDRTSVLHVMVKKGQVTGVETDKGQIECQYFVNC 240
PEDAVVSSADVALALASAASQNGVQIYDRTSVLHVMVKKGQVTGVETDKGQIECQYFVNC
Sbjct: 181 PEDAVVSSADVALALASAASQNGVQIYDRTSVLHVMVKKGQVTGVETDKGQIECQYFVNC 240
Query: 241 AGQWAYELGLSNEEPVSIPLHACEHFYLLTRPLETPLQSSTPTIVDADGRIYIRNWQGGI 300
AGQWAYELGLSNEEPVSIPLHACEHFYLLTRPLETPLQSSTPTIVDADGRIYIRNWQGGI
Sbjct: 241 AGQWAYELGLSNEEPVSIPLHACEHFYLLTRPLETPLQSSTPTIVDADGRIYIRNWQGGI 300
Query: 301 LSGGFEKNPKPIFTEGKNQLEIQNLQEDWDHFEPLLSSLLRRMPELETLEIMKLVNCPET 360
LSGGFEKNPKPIFTEGKNQLEIQNLQEDWDHFEPLLSSLLRRMPELETLEIMKLVNCPET
Sbjct: 301 LSGGFEKNPKPIFTEGKNQLEIQNLQEDWDHFEPLLSSLLRRMPELETLEIMKLVNCPET 360
Query: 361 FTPDMRCIMGESPAVQGYFVLAGMNSAGLSFGGGAGKYLAEWMVHGYPSENVWELDLKRF 420
FTPDMRCIMGESPAVQGYFVLAGMNSAGLSFGGGAGKYLAEWMVHGYPSENVWELDLKRF
Sbjct: 361 FTPDMRCIMGESPAVQGYFVLAGMNSAGLSFGGGAGKYLAEWMVHGYPSENVWELDLKRF 420
Query: 421 GALQSSRTFLRHRVMEVMPLMYDLKVPRWDFQTGRQLRTSPLYDRLDAQGARWMEKHGFE 480
GALQSSRTFLRHRVMEVMPLMYDLKVPRWDFQTGRQLRTSPLYDRLDAQGARWMEKHGFE
Sbjct: 421 GALQSSRTFLRHRVMEVMPLMYDLKVPRWDFQTGRQLRTSPLYDRLDAQGARWMEKHGFE 480
Query: 481 RPKYFVPPDKDLLALEQSKTFYKPDWFDIVESEVKCCKEAVCVIDMSSFTKFEITSTGDQ 540
RPKYFVPPDKDLLALEQSKTFYKPDWFDIVESEVKCCKEAVCVIDMSSFTKFEITSTGDQ
Sbjct: 481 RPKYFVPPDKDLLALEQSKTFYKPDWFDIVESEVKCCKEAVCVIDMSSFTKFEITSTGDQ 540
Query: 541 ALEVLQYLFSNDLDVPVGHIVHTGMLNEGGGYENDCSIARLNKRSFFMISPTDQQVHCWA 600
ALEVLQYLFSNDLDVPVGHIVHTGMLNEGGGYENDCSIARLNKRSFFMISPTDQQVHCWA
Sbjct: 541 ALEVLQYLFSNDLDVPVGHIVHTGMLNEGGGYENDCSIARLNKRSFFMISPTDQQVHCWA 600
Query: 601 WLKKHMPKDSNLLLEDVTWKYTALNLIGPRAVDVLSELSYAPMTPDHFPSLFCKEMSVGY 660
WLKKHMPKDSNLLLEDVTWKYTALNLIGPRAVDVLSELSYAPMTPDHFPSLFCKEMSVGY
Sbjct: 601 WLKKHMPKDSNLLLEDVTWKYTALNLIGPRAVDVLSELSYAPMTPDHFPSLFCKEMSVGY 660
Query: 661 ANGIRVMSMTHTGEPGFMLYIPIEYALHVYNEVMSVGQKYGIRNAGYYALRSLRIEKFFA 720
ANGIRVMSMTHTGEPGFMLYIPIEYALHVYNEVMSVGQKYGIRNAGYYALRSLRIEKFFA
Sbjct: 661 ANGIRVMSMTHTGEPGFMLYIPIEYALHVYNEVMSVGQKYGIRNAGYYALRSLRIEKFFA 720
Query: 721 FWGQDINNLTTPLECGRESRVKLEKGMDFIGRDALLQQKQNGVYKRLTMFILDDHDSDLD 780
FWGQDINNLTTPLECGRESRVKLEKGMDFIGRDALLQQKQNGVYKRLTMFILDDHDSDLD
Sbjct: 721 FWGQDINNLTTPLECGRESRVKLEKGMDFIGRDALLQQKQNGVYKRLTMFILDDHDSDLD 780
Query: 781 LWPWWGEPIYRNGQYVGKTTSSAYSYSLERHVCLGFVHNFSEDTGEEQVVTADFINRGEY 840
LWPWWGEPIYRNGQYVGKTTSSAYSYSLERHVCLGFVHNFSEDTGEEQVVTADFINRGEY
Sbjct: 781 LWPWWGEPIYRNGQYVGKTTSSAYSYSLERHVCLGFVHNFSEDTGEEQVVTADFINRGEY 840
Query: 841 EIDIAGYRFQAKAKLYPVASLFTQKRRKDDMELSDLHGK 879
EIDIAGYRFQAKAKLYPVASLFTQKRRKDDMELSDLHGK
Sbjct: 841 EIDIAGYRFQAKAKLYPVASLFTQKRRKDDMELSDLHGK 879
>gi|197927446 sarcosine dehydrogenase precursor [Homo sapiens]
Length = 918
Score = 429 bits (1102), Expect = e-120
Identities = 284/889 (31%), Positives = 451/889 (50%), Gaps = 68/889 (7%)
Query: 13 QRASPGWQNWSSARNSTSAAEARSMALPTQAQVVICGGGITGTSVAYHLSKMGWKDIVLL 72
+++ P + + ++ A+ S LP+ A VV+ GGG G YHL+K+G VLL
Sbjct: 37 EKSVPYQRTLKEGQGTSVVAQGPSRPLPSTANVVVIGGGSLGCQTLYHLAKLGMSGAVLL 96
Query: 73 EQGRLAAGSTRFCAGILSTARHLTIEQKMADYSNKLYY-QLEQETGIQTGYTRTGSIFLA 131
E+ RL +G+T AG+L R +E ++ ++ ++ +LE+ETG+ TG+ + G +F+A
Sbjct: 97 ERERLTSGTTWHTAGLLWQLRPSDVEVELLAHTRRVVSRELEEETGLHTGWIQNGGLFIA 156
Query: 132 QTQDRLISLKRINAGLNVIGIPSEIISPKKVAELHHLLNVHDLVGAMHVPEDAVVSSADV 191
+ RL KR+ + G+ S ++SP + L+ L+NV DL G ++VP D + A
Sbjct: 157 SNRQRLDEYKRLMSLGKAYGVESHVLSPAETKTLYPLMNVDDLYGTLYVPHDGTMDPAGT 216
Query: 192 ALALASAASQNGVQIYDRTSVLHVMVKKG-----QVTGVETDKGQIECQYFVNCAGQWAY 246
LA AAS G Q+ + V + V +V GVET G I+ VNCAG WA
Sbjct: 217 CTTLARAASARGAQVIENCPVTGIRVWTDDFGVRRVAGVETQHGSIQTPCVVNCAGVWAS 276
Query: 247 ELGLSNEEPVSIPLHACEHFYLLTRPLETPLQSSTPTIVDADGRIYIRNWQGGILS-GGF 305
+G V +PL A H Y++T +E + P + D D +Y+R QG LS GG+
Sbjct: 277 AVG--RMAGVKVPLVAMHHAYVVTERIEGI--QNMPNVRDHDASVYLR-LQGDALSVGGY 331
Query: 306 EKNPKPIFTEGKNQLEIQNLQEDWDHFEPLLSSLLRRMPELETLEIMKLVNCPETFTPDM 365
E NP + E ++ DW+ F + + R+P LE I V PE+FTPD
Sbjct: 332 EANPI-FWEEVSDKFAFGLFDLDWEVFTQHIEGAINRVPVLEKTGIKSTVCGPESFTPDH 390
Query: 366 RCIMGESPAVQGYFVLAGMNSAGLSFGGGAGKYLAEWMVHGYPSENVWELDLKRF-GALQ 424
+ +MGE+P ++G+F+ G NSAG+ GGG G+ LA W++HG P +++ D++RF +L
Sbjct: 391 KPLMGEAPELRGFFLGCGFNSAGMMLGGGCGQELAHWIIHGRPEKDMHGYDIRRFHHSLT 450
Query: 425 SSRTFLRHRVMEVMPLMYDLKVPRWDFQTGRQLRTSPLYDRLDAQGARWMEKHGFERPKY 484
++R R E Y + P + GR +R PL++ L QG + E+HG+ERP +
Sbjct: 451 DHPRWIRERSHESYAKNYSVVFPHDEPLAGRNMRRDPLHEELLGQGCVFQERHGWERPGW 510
Query: 485 FVPPD-----------------------KDLLALEQSKTFYKPDWFDIVESEVKCCKEAV 521
F P + LLA E TF P D ++ E C+ A
Sbjct: 511 FHPRGPAPVLEYDYYGAYGSRAHEDYAYRRLLADEY--TFAFPPHHDTIKKECLACRGAA 568
Query: 522 CVIDMSSFTKFEITSTGDQALEVLQYLFSNDLDVPVGHIVHTGMLNEGGGYENDCSIARL 581
V DMS F KF + G A + +LFS D+ P G V+T MLN GG E+D +++RL
Sbjct: 569 AVFDMSYFGKFYL--VGLDARKAADWLFSADVSRPPGSTVYTCMLNHRGGTESDLTVSRL 626
Query: 582 -------------NKRSFFMISPTDQQVHCWAWLKKHM-PKDSNLLLEDVTWKYTALNLI 627
+++ H W+ + + + S L D + +++
Sbjct: 627 APSHQASPLAPAFEGDGYYLAMGGAVAQHNWSHITTVLQDQKSQCQLIDSSEDLGMISIQ 686
Query: 628 GPRAVDVLSELSYAPMTPDHFPSLFCKEMSVGYANGIRVMSMTHTGEPGFMLYIPIEYAL 687
GP + +L E+ A ++ + FP K + + +R M ++ GE G+ L+IP +
Sbjct: 687 GPASRAILQEVLDADLSNEAFPFSTHKLLRAA-GHLVRAMRLSFVGELGWELHIPKASCV 745
Query: 688 HVYNEVMSVGQKYGIRNAGYYALRSLRIEKFFAFWGQDINNLTTPLECGRESRVKLEKGM 747
VY VM+ G K+G+ NAGY A+ SL IEK + W D+ +PLE G KL+ +
Sbjct: 746 PVYRAVMAAGAKHGLINAGYRAIDSLSIEKGYRHWHADLRPDDSPLEAGLAFTCKLKSPV 805
Query: 748 DFIGRDALLQQKQNGVYKRLTMFILDDHDSDLDLWPWWG-EPIYRNGQYVGKTTSSAYSY 806
F+GR+AL QQ+ G+ +RL F ++D P +G E I+RNGQ VG + + +
Sbjct: 806 PFLGREALEQQRAAGLRRRLVCFTMEDK------VPMFGLEAIWRNGQVVGHVRRADFGF 859
Query: 807 SLERHVCLGFVHNFSEDTGEEQVVTADFINRGEYEIDIAGYRFQAKAKL 855
++++ + G++H+ S V+ DF+ G+Y ++ G + A+A L
Sbjct: 860 AIDKTIAYGYIHDPSGGP-----VSLDFVKSGDYALERMGVTYGAQAHL 903
>gi|21361378 sarcosine dehydrogenase precursor [Homo sapiens]
Length = 918
Score = 429 bits (1102), Expect = e-120
Identities = 284/889 (31%), Positives = 451/889 (50%), Gaps = 68/889 (7%)
Query: 13 QRASPGWQNWSSARNSTSAAEARSMALPTQAQVVICGGGITGTSVAYHLSKMGWKDIVLL 72
+++ P + + ++ A+ S LP+ A VV+ GGG G YHL+K+G VLL
Sbjct: 37 EKSVPYQRTLKEGQGTSVVAQGPSRPLPSTANVVVIGGGSLGCQTLYHLAKLGMSGAVLL 96
Query: 73 EQGRLAAGSTRFCAGILSTARHLTIEQKMADYSNKLYY-QLEQETGIQTGYTRTGSIFLA 131
E+ RL +G+T AG+L R +E ++ ++ ++ +LE+ETG+ TG+ + G +F+A
Sbjct: 97 ERERLTSGTTWHTAGLLWQLRPSDVEVELLAHTRRVVSRELEEETGLHTGWIQNGGLFIA 156
Query: 132 QTQDRLISLKRINAGLNVIGIPSEIISPKKVAELHHLLNVHDLVGAMHVPEDAVVSSADV 191
+ RL KR+ + G+ S ++SP + L+ L+NV DL G ++VP D + A
Sbjct: 157 SNRQRLDEYKRLMSLGKAYGVESHVLSPAETKTLYPLMNVDDLYGTLYVPHDGTMDPAGT 216
Query: 192 ALALASAASQNGVQIYDRTSVLHVMVKKG-----QVTGVETDKGQIECQYFVNCAGQWAY 246
LA AAS G Q+ + V + V +V GVET G I+ VNCAG WA
Sbjct: 217 CTTLARAASARGAQVIENCPVTGIRVWTDDFGVRRVAGVETQHGSIQTPCVVNCAGVWAS 276
Query: 247 ELGLSNEEPVSIPLHACEHFYLLTRPLETPLQSSTPTIVDADGRIYIRNWQGGILS-GGF 305
+G V +PL A H Y++T +E + P + D D +Y+R QG LS GG+
Sbjct: 277 AVG--RMAGVKVPLVAMHHAYVVTERIEGI--QNMPNVRDHDASVYLR-LQGDALSVGGY 331
Query: 306 EKNPKPIFTEGKNQLEIQNLQEDWDHFEPLLSSLLRRMPELETLEIMKLVNCPETFTPDM 365
E NP + E ++ DW+ F + + R+P LE I V PE+FTPD
Sbjct: 332 EANPI-FWEEVSDKFAFGLFDLDWEVFTQHIEGAINRVPVLEKTGIKSTVCGPESFTPDH 390
Query: 366 RCIMGESPAVQGYFVLAGMNSAGLSFGGGAGKYLAEWMVHGYPSENVWELDLKRF-GALQ 424
+ +MGE+P ++G+F+ G NSAG+ GGG G+ LA W++HG P +++ D++RF +L
Sbjct: 391 KPLMGEAPELRGFFLGCGFNSAGMMLGGGCGQELAHWIIHGRPEKDMHGYDIRRFHHSLT 450
Query: 425 SSRTFLRHRVMEVMPLMYDLKVPRWDFQTGRQLRTSPLYDRLDAQGARWMEKHGFERPKY 484
++R R E Y + P + GR +R PL++ L QG + E+HG+ERP +
Sbjct: 451 DHPRWIRERSHESYAKNYSVVFPHDEPLAGRNMRRDPLHEELLGQGCVFQERHGWERPGW 510
Query: 485 FVPPD-----------------------KDLLALEQSKTFYKPDWFDIVESEVKCCKEAV 521
F P + LLA E TF P D ++ E C+ A
Sbjct: 511 FHPRGPAPVLEYDYYGAYGSRAHEDYAYRRLLADEY--TFAFPPHHDTIKKECLACRGAA 568
Query: 522 CVIDMSSFTKFEITSTGDQALEVLQYLFSNDLDVPVGHIVHTGMLNEGGGYENDCSIARL 581
V DMS F KF + G A + +LFS D+ P G V+T MLN GG E+D +++RL
Sbjct: 569 AVFDMSYFGKFYL--VGLDARKAADWLFSADVSRPPGSTVYTCMLNHRGGTESDLTVSRL 626
Query: 582 -------------NKRSFFMISPTDQQVHCWAWLKKHM-PKDSNLLLEDVTWKYTALNLI 627
+++ H W+ + + + S L D + +++
Sbjct: 627 APSHQASPLAPAFEGDGYYLAMGGAVAQHNWSHITTVLQDQKSQCQLIDSSEDLGMISIQ 686
Query: 628 GPRAVDVLSELSYAPMTPDHFPSLFCKEMSVGYANGIRVMSMTHTGEPGFMLYIPIEYAL 687
GP + +L E+ A ++ + FP K + + +R M ++ GE G+ L+IP +
Sbjct: 687 GPASRAILQEVLDADLSNEAFPFSTHKLLRAA-GHLVRAMRLSFVGELGWELHIPKASCV 745
Query: 688 HVYNEVMSVGQKYGIRNAGYYALRSLRIEKFFAFWGQDINNLTTPLECGRESRVKLEKGM 747
VY VM+ G K+G+ NAGY A+ SL IEK + W D+ +PLE G KL+ +
Sbjct: 746 PVYRAVMAAGAKHGLINAGYRAIDSLSIEKGYRHWHADLRPDDSPLEAGLAFTCKLKSPV 805
Query: 748 DFIGRDALLQQKQNGVYKRLTMFILDDHDSDLDLWPWWG-EPIYRNGQYVGKTTSSAYSY 806
F+GR+AL QQ+ G+ +RL F ++D P +G E I+RNGQ VG + + +
Sbjct: 806 PFLGREALEQQRAAGLRRRLVCFTMEDK------VPMFGLEAIWRNGQVVGHVRRADFGF 859
Query: 807 SLERHVCLGFVHNFSEDTGEEQVVTADFINRGEYEIDIAGYRFQAKAKL 855
++++ + G++H+ S V+ DF+ G+Y ++ G + A+A L
Sbjct: 860 AIDKTIAYGYIHDPSGGP-----VSLDFVKSGDYALERMGVTYGAQAHL 903
>gi|24797151 dimethylglycine dehydrogenase precursor [Homo sapiens]
Length = 866
Score = 363 bits (932), Expect = e-100
Identities = 254/804 (31%), Positives = 415/804 (51%), Gaps = 42/804 (5%)
Query: 42 QAQVVICGGGITGTSVAYHLSKMGWKDIVLLEQGRLAAGSTRFCAGILSTARHLTIEQKM 101
+A+ VI GGG G S+AYHL+K G KD+VLLE+ L AGST AG L+T H I K
Sbjct: 49 RAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAG-LTTYFHPGINLKK 107
Query: 102 ADYSN-KLYYQLEQETGIQTGYTRTGSIFLAQTQDRLISLKRINAGLNVIGIPSEIISPK 160
Y + KLY +LE+ETG G+ + GSI LA T R+ K +I P+
Sbjct: 108 IHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPE 167
Query: 161 KVAELHHLLNVHDLVGAMHVPEDAVVSSADVALALASAASQNGVQIYDRTSVLHVMVKKG 220
K+ E+ LLN++ ++ ++ P D + + +ALA+ A + G + V + +
Sbjct: 168 KIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSD 227
Query: 221 QVTGVETDKGQIECQYFVNCAGQWAYELG--LSNEEPVSIPLHACEHFYLLTRPLET--P 276
VET +G + VN AG WA E+G + E P+ IP+ +H Y++T +
Sbjct: 228 GTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPL-IPV---QHQYVVTSTISEVKA 283
Query: 277 LQSSTPTIVDADGRIYIRNWQGGILSGGFEKNPKPIFTE-----------GKNQLEIQNL 325
L+ P + D +G Y+R + G+L G +E K + GK E
Sbjct: 284 LKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKELFE---- 339
Query: 326 QEDWDHFEPLLSSLLRRMPELETLEIMKLVNCPETFTPDMRCIMGESPAVQGYFVLAGMN 385
D D + + + +P L+ +I+ +VN P T++PD+ ++G V+ Y+V G
Sbjct: 340 -SDLDRIMEHIKAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGVRNYWVAIGFG 398
Query: 386 SAGLSFGGGAGKYLAEWMVHGYPSENVWELDLKRFGALQSSRTFLRHRVMEVMPLMYDLK 445
G+ GG GKYL++W++HG P ++ ELD R+G +++ + + E +
Sbjct: 399 Y-GIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQ-YTEAKARESYGFNNIVG 456
Query: 446 VPRWDFQTGRQL-RTSPLYDRLDAQGARWMEKHGFERPKYFVPPDKDLLALEQSKTFYKP 504
P+ + GR R S LY RL+++ + G+E+P +F P +D + +F +
Sbjct: 457 YPKEERFAGRPTQRVSGLYQRLESKCSMGFHA-GWEQPHWFYKPGQDT---QYRPSFRRT 512
Query: 505 DWFDIVESEVKCCKEAVCVIDMSSFTKFEITSTGDQALEVLQYLFSNDLDVPVGHIVHTG 564
+WF+ V SE K + V V D+S F KF I G ++ +L +LF+N + VG +
Sbjct: 513 NWFEPVGSEYKQVMQRVAVTDLSPFGKFNIK--GQDSIRLLDHLFANVIP-KVGFTNISH 569
Query: 565 MLNEGGGYENDCSIARLNKRSFFMISPTDQQVHCWAWLKKHMPKDS-NLLLEDVTWKYTA 623
ML G + +++ + F +I+ + ++H W+++ K ++ ++++T +
Sbjct: 570 MLTPKGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEEAVKGGYDVEIKNITDELGV 629
Query: 624 LNLIGPRAVDVLSELSYAPMTPDHFPSLFCKEMSVGYANGIRVMSMTHTGEPGFMLYIPI 683
L + GP+A VL +L+ ++ D F L K + V + + +++TGE G+ LY
Sbjct: 630 LGVAGPQARKVLQKLTSEDLSDDVFKFLQTKSLKVSNIP-VTAIRISYTGELGWELYHRR 688
Query: 684 EYALHVYNEVMSVGQKYGIRNAGYYALRSLRIEKFFAFWGQDINNLTTPLECGRESRVKL 743
E ++ +Y+ +M+ GQ+ GI N G YA+ +LR+EK F WG ++N T PLE G E VKL
Sbjct: 689 EDSVALYDAIMNAGQEEGIDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKL 748
Query: 744 EKGMDFIGRDALLQQKQNGVYKRLTMFILDDHDSDLDLWPWWGEPIYRNGQYVGKTTSSA 803
K DFIG+ AL Q K G+ +RL L D D P E I+ NG+ VG TTS +
Sbjct: 749 NKPADFIGKQALKQIKAKGLKRRLVCLTLATDDVD----PEGNESIWYNGKVVGNTTSGS 804
Query: 804 YSYSLERHVCLGFVHNFSEDTGEE 827
YSYS+++ + +V + G++
Sbjct: 805 YSYSIQKSLAFAYVPVQLSEVGQQ 828
>gi|60499001 pipecolic acid oxidase [Homo sapiens]
Length = 390
Score = 61.6 bits (148), Expect = 3e-09
Identities = 92/396 (23%), Positives = 167/396 (42%), Gaps = 39/396 (9%)
Query: 46 VICGGGITGTSVAYHLSKMGWKDIVLLEQGRL--AAGSTRFCAGILSTARHLTIEQKMAD 103
++ G GI G AYHL+K K I+LLEQ L + GS+ + I+ A +M
Sbjct: 11 IVIGAGIQGCFTAYHLAKHR-KRILLLEQFFLPHSRGSSHGQSRIIRKAYLEDFYTRMMH 69
Query: 104 YSNKLYYQLEQETGIQTGYTRTGSIFLAQTQDRLISLKRINAGLNVIGIPSEIISPKKVA 163
+++ QLE E G Q + +TG + L +++ LK I A L+ + + +S +++
Sbjct: 70 ECYQIWAQLEHEAGTQL-HRQTGLLLLGMKENQ--ELKTIQANLSRQRVEHQCLSSEELK 126
Query: 164 ELHHLLNVHDLVGAMHVPEDA--VVSSADVALALASAASQNGVQIYDRTSVLHVMVKKGQ 221
+ N+ G + + +++ V+ + AL A Q G + D V V + G
Sbjct: 127 Q--RFPNIRLPRGEVGLLDNSGGVIYAYKALRALQDAIRQLGGIVRDGEKV--VEINPGL 182
Query: 222 VTGVETDKGQIECQYFVNCAGQWAYEL--GLSNEEPV-SIPLHACEHFYLLTRPLETPLQ 278
+ V+T + + V AG W +L L E P+ ++ ++ C ++ P +
Sbjct: 183 LVTVKTTSRSYQAKSLVITAGPWTNQLLRPLGIEMPLQTLRINVC--YWREMVPGSYGVS 240
Query: 279 SSTPTIVDADGRIYIRNWQG-------GILSGGFEKNPKPIFTEGKN----QLEIQNLQE 327
+ P + W G G+ +G + K + G + + + +
Sbjct: 241 QAFPCFL----------WLGLCPHHIYGLPTGEYPGLMKVSYHHGNHADPEERDCPTART 290
Query: 328 DWDHFEPLLSSLLRRMPELETLEIMKLVNCPETFTPDMRCIMGESPAVQGYFVLAGMNSA 387
D + L S + +P+L+ E + +C T TPD + I+ P + AG +
Sbjct: 291 DIGDVQILSSFVRDHLPDLKP-EPAVIESCMYTNTPDEQFILDRHPKYDNIVIGAGFSGH 349
Query: 388 GLSFGGGAGKYLAEWMVHGYPSENVWELDLKRFGAL 423
G GK L E + PS ++ + RF +L
Sbjct: 350 GFKLAPVVGKILYELSMKLTPSYDLAPFRISRFPSL 385
>gi|44662838 aminomethyltransferase [Homo sapiens]
Length = 403
Score = 61.2 bits (147), Expect = 4e-09
Identities = 69/277 (24%), Positives = 111/277 (40%), Gaps = 58/277 (20%)
Query: 567 NEGGGYENDCSIARLNKRSFFMISPTDQQVHCWAWLKKHMPKDSNLLLEDV--------- 617
NE GG +D + ++ +++S CW KD L+ + V
Sbjct: 121 NEAGGILDDLIVTNTSEGHLYVVS----NAGCWE-------KDLALMQDKVRELQNQGRD 169
Query: 618 ----TWKYTALNLIGPRAVDVLSELSYAPMTPD--HFPSLFCKEMSVGYANGIRVMSMTH 671
L L GP A VL A + D P + M V +G RV +
Sbjct: 170 VGLEVLDNALLALQGPTAAQVLQ----AGVADDLRKLPFMTSAVMEVFGVSGCRVTRCGY 225
Query: 672 TGEPGFMLYIPIEYALHVYNEVMSVGQKYGIRNAGYYALRSLRIEKFFAFWGQDINNLTT 731
TGE G + +P+ A+H+ ++ + ++ AG A SLR+E +G DI+ TT
Sbjct: 226 TGEDGVEISVPVAGAVHLATAILKNPE---VKLAGLAARDSLRLEAGLCLYGNDIDEHTT 282
Query: 732 PLE------CGRESRVKLEKGMDFIGRDALLQQKQNGVYKRLTMFILDD-----HDSDLD 780
P+E G+ R MDF G ++ Q + V +R + + H L+
Sbjct: 283 PVEGSLSWTLGKRRRA----AMDFPGAKVIVPQLKGRVQRRRVGLMCEGAPMRAHSPILN 338
Query: 781 LWPWWGEPIYRNGQYVGKTTSSAYSYSLERHVCLGFV 817
+ G +G TS S SL+++V +G+V
Sbjct: 339 M----------EGTKIGTVTSGCPSPSLKKNVAMGYV 365
>gi|8923708 FAD-dependent oxidoreductase domain containing 1 [Homo
sapiens]
Length = 486
Score = 57.0 bits (136), Expect = 8e-08
Identities = 89/412 (21%), Positives = 159/412 (38%), Gaps = 58/412 (14%)
Query: 40 PTQAQVVICGGGITGTSVAYHLSKM----GWKDIVLLEQGRL-AAGSTRFCAGIL----S 90
P + VVI GGG+ G SVAY L K+ G ++++E+ + ST G + S
Sbjct: 61 PEHSDVVIVGGGVLGLSVAYWLKKLESRRGAIRVLVVERDHTYSQASTGLSVGGICQQFS 120
Query: 91 TARHLTIEQKMADYSNKL--YYQLEQETGIQTGYTRTGSIFLAQTQDRLISLKRINAGLN 148
++ + A + + Y + + + +G + LA +D +
Sbjct: 121 LPENIQLSLFSASFLRNINEYLAVVDAPPLDLRFNPSGYLLLASEKDAAAMESNVKVQRQ 180
Query: 149 VIGIPSEIISPKKVAELHHLLNVHDLVGAMHVPEDA--------------VVSSADVALA 194
G ++SP ++ +N + A + ED V S V
Sbjct: 181 E-GAKVSLMSPDQLRNKFPWINTEGVALASYGMEDEGWFDPWCLLQGLRRKVQSLGVLFC 239
Query: 195 LAS-----AASQNGVQIYDRTSVLHVMVKKGQVTGVETDKG----QIECQYFVNCAGQWA 245
++SQ + D+ VL K+ V+ D+ +EC +N AG W+
Sbjct: 240 QGEVTRFVSSSQRMLTTDDKAVVL----KRIHEVHVKMDRSLEYQPVECAIVINAAGAWS 295
Query: 246 YEL----GLSNEEP-----VSIPLHACEHFYLLTRPLETPLQSSTPTIVDADGRIYIRNW 296
++ G+ P +P+ + + + + P TP + D G + R
Sbjct: 296 AQIAALAGVGEGPPGTLQGTKLPVEPRKRYVYVWHCPQGP-GLETPLVADTSGAYFRREG 354
Query: 297 QGGILSGGFEKNPKPIFTEGKNQLEIQNLQEDWDHF-EPLLSSLLRRMPELETLEIMKL- 354
G GG ++P TE + + + NL+ D D F + + L R+P ETL++
Sbjct: 355 LGSNYLGG--RSP----TE-QEEPDPANLEVDHDFFQDKVWPHLALRVPAFETLKVQSAW 407
Query: 355 VNCPETFTPDMRCIMGESPAVQGYFVLAGMNSAGLSFGGGAGKYLAEWMVHG 406
+ T D ++G P V + G + GL G G+ +AE ++ G
Sbjct: 408 AGYYDYNTFDQNGVVGPHPLVVNMYFATGFSGHGLQQAPGIGRAVAEMVLKG 459
>gi|13376331 L-2-hydroxyglutarate dehydrogenase precursor [Homo
sapiens]
Length = 463
Score = 47.4 bits (111), Expect = 6e-05
Identities = 70/292 (23%), Positives = 121/292 (41%), Gaps = 34/292 (11%)
Query: 6 LLSIVGRQRA-----SPGWQNWSSARNSTSAAEARSMALPTQAQVVICGGGITGTSVAYH 60
L+ GR R SPG ++S R +RS A + +VI GGGI G + A
Sbjct: 8 LVGACGRARGLFAGGSPGACGFASGRPRPLCGGSRS-ASTSSFDIVIVGGGIVGLASARA 66
Query: 61 LS-KMGWKDIVLLEQGR-LAAGSTRFCAGILSTARHL---TIEQKMADYSNKLYYQLEQE 115
L + I +LE+ + LA T +G++ + + +++ K+ L Y+ Q+
Sbjct: 67 LILRHPSLSIGVLEKEKDLAVHQTGHNSGVIHSGIYYKPESLKAKLCVQGAALLYEYCQQ 126
Query: 116 TGIQTGYTRTGSIFLAQTQDRLISLKRINAGLNVIGIPS-EIISPKKVAELHHLLNVHDL 174
GI Y + G + +A Q+ + L+ + G+P +I + + +
Sbjct: 127 KGIS--YKQCGKLIVAVEQEEIPRLQALYEKGLQNGVPGLRLIQQEDIKKKEPYCRG--- 181
Query: 175 VGAMHVPEDAVVSSADVALALASAASQNGVQIYDRTSVLHVMVKKGQVTG---------- 224
+ A+ P +V VAL+ A + G + V + + K +
Sbjct: 182 LMAIDCPHTGIVDYRQVALSFAQDFQEAGGSVLTNFEVKGIEMAKESPSRSIDGMQYPIV 241
Query: 225 VETDKGQ-IECQYFVNCAGQWA---YELGLSNEEPVSIPLHACEHFYLLTRP 272
++ KG+ I CQY V CAG ++ EL +P +P YLL +P
Sbjct: 242 IKNTKGEEIRCQYVVTCAGLYSDRISELSGCTPDPRIVPFRG---DYLLLKP 290
>gi|28559080 spermine oxidase isoform 4 [Homo sapiens]
Length = 532
Score = 31.6 bits (70), Expect = 3.4
Identities = 16/54 (29%), Positives = 29/54 (53%)
Query: 20 QNWSSARNSTSAAEARSMALPTQAQVVICGGGITGTSVAYHLSKMGWKDIVLLE 73
Q+ S+ +S +R + Q +VV+ G G+ G + A L + G+ D+ +LE
Sbjct: 2 QSCESSGDSADDPLSRGLRRRGQPRVVVIGAGLAGLAAAKALLEQGFTDVTVLE 55
>gi|28559078 spermine oxidase isoform 3 [Homo sapiens]
Length = 190
Score = 31.6 bits (70), Expect = 3.4
Identities = 16/54 (29%), Positives = 29/54 (53%)
Query: 20 QNWSSARNSTSAAEARSMALPTQAQVVICGGGITGTSVAYHLSKMGWKDIVLLE 73
Q+ S+ +S +R + Q +VV+ G G+ G + A L + G+ D+ +LE
Sbjct: 2 QSCESSGDSADDPLSRGLRRRGQPRVVVIGAGLAGLAAAKALLEQGFTDVTVLE 55
>gi|28559076 spermine oxidase isoform 2 [Homo sapiens]
Length = 502
Score = 31.6 bits (70), Expect = 3.4
Identities = 16/54 (29%), Positives = 29/54 (53%)
Query: 20 QNWSSARNSTSAAEARSMALPTQAQVVICGGGITGTSVAYHLSKMGWKDIVLLE 73
Q+ S+ +S +R + Q +VV+ G G+ G + A L + G+ D+ +LE
Sbjct: 2 QSCESSGDSADDPLSRGLRRRGQPRVVVIGAGLAGLAAAKALLEQGFTDVTVLE 55
>gi|28559074 spermine oxidase isoform 1 [Homo sapiens]
Length = 555
Score = 31.6 bits (70), Expect = 3.4
Identities = 16/54 (29%), Positives = 29/54 (53%)
Query: 20 QNWSSARNSTSAAEARSMALPTQAQVVICGGGITGTSVAYHLSKMGWKDIVLLE 73
Q+ S+ +S +R + Q +VV+ G G+ G + A L + G+ D+ +LE
Sbjct: 2 QSCESSGDSADDPLSRGLRRRGQPRVVVIGAGLAGLAAAKALLEQGFTDVTVLE 55
>gi|218083730 zinc finger protein 237 isoform 3 [Homo sapiens]
Length = 669
Score = 31.6 bits (70), Expect = 3.4
Identities = 13/26 (50%), Positives = 18/26 (69%)
Query: 312 IFTEGKNQLEIQNLQEDWDHFEPLLS 337
+F EGKNQL+ +N +DW H +LS
Sbjct: 595 LFGEGKNQLKNENGCKDWQHLSHILS 620
>gi|32967305 coenzyme Q6 homolog isoform a [Homo sapiens]
Length = 468
Score = 31.6 bits (70), Expect = 3.4
Identities = 27/83 (32%), Positives = 35/83 (42%), Gaps = 21/83 (25%)
Query: 2 MFYRLLSIVGRQRASP------GWQNWSSARNSTSAAEARSMALPTQAQVVICGGGITGT 55
M RL+S G RA+P W+ WS A T VV+ GGG+ G
Sbjct: 1 MAARLVSRCGAVRAAPHSGPLVSWRRWSGASTDTVY------------DVVVSGGGLVGA 48
Query: 56 SVAYHLS---KMGWKDIVLLEQG 75
++A L K I+LLE G
Sbjct: 49 AMACALGYDIHFHDKKILLLEAG 71
>gi|239756515 PREDICTED: similar to Putative 3-beta-HSD family
protein ENSP00000330812 [Homo sapiens]
Length = 422
Score = 31.2 bits (69), Expect = 4.4
Identities = 19/67 (28%), Positives = 37/67 (55%), Gaps = 5/67 (7%)
Query: 14 RASPGWQNWSSARNSTSAAEARSMALPTQAQ----VVICGGGITGTSVAYHLSKMGWKDI 69
+++P + + + + A + ++ A PT+A +V GGG G S+ HL+K G +
Sbjct: 2 KSNPPRSSLEACKAAGQAPQQKTQAKPTKAARQKVLVTGGGGYLGFSLGSHLAKSG-TSV 60
Query: 70 VLLEQGR 76
+LL++ R
Sbjct: 61 ILLDRRR 67
>gi|239751020 PREDICTED: hypothetical protein XP_002347673 [Homo
sapiens]
Length = 422
Score = 31.2 bits (69), Expect = 4.4
Identities = 19/67 (28%), Positives = 37/67 (55%), Gaps = 5/67 (7%)
Query: 14 RASPGWQNWSSARNSTSAAEARSMALPTQAQ----VVICGGGITGTSVAYHLSKMGWKDI 69
+++P + + + + A + ++ A PT+A +V GGG G S+ HL+K G +
Sbjct: 2 KSNPPRSSLEACKAAGQAPQQKTQAKPTKAARQKVLVTGGGGYLGFSLGSHLAKSG-TSV 60
Query: 70 VLLEQGR 76
+LL++ R
Sbjct: 61 ILLDRRR 67
>gi|239745448 PREDICTED: hypothetical protein XP_002343493 [Homo
sapiens]
Length = 422
Score = 31.2 bits (69), Expect = 4.4
Identities = 19/67 (28%), Positives = 37/67 (55%), Gaps = 5/67 (7%)
Query: 14 RASPGWQNWSSARNSTSAAEARSMALPTQAQ----VVICGGGITGTSVAYHLSKMGWKDI 69
+++P + + + + A + ++ A PT+A +V GGG G S+ HL+K G +
Sbjct: 2 KSNPPRSSLEACKAAGQAPQQKTQAKPTKAARQKVLVTGGGGYLGFSLGSHLAKSG-TSV 60
Query: 70 VLLEQGR 76
+LL++ R
Sbjct: 61 ILLDRRR 67
>gi|170650615 protoporphyrinogen oxidase [Homo sapiens]
Length = 477
Score = 31.2 bits (69), Expect = 4.4
Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 1/44 (2%)
Query: 45 VVICGGGITGTSVAYHLSKMGW-KDIVLLEQGRLAAGSTRFCAG 87
VV+ GGGI+G + +YHLS+ +VL+E G R G
Sbjct: 5 VVVLGGGISGLAASYHLSRAPCPPKVVLVESSERLGGWIRSVRG 48
>gi|4506001 protoporphyrinogen oxidase [Homo sapiens]
Length = 477
Score = 31.2 bits (69), Expect = 4.4
Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 1/44 (2%)
Query: 45 VVICGGGITGTSVAYHLSKMGW-KDIVLLEQGRLAAGSTRFCAG 87
VV+ GGGI+G + +YHLS+ +VL+E G R G
Sbjct: 5 VVVLGGGISGLAASYHLSRAPCPPKVVLVESSERLGGWIRSVRG 48
>gi|223005862 echinoderm microtubule associated protein like 6 [Homo
sapiens]
Length = 1958
Score = 30.8 bits (68), Expect = 5.8
Identities = 23/76 (30%), Positives = 35/76 (46%), Gaps = 3/76 (3%)
Query: 803 AYSYSLERHVCLGFVHNFSEDTGEEQVVTADFINRGEYEIDIAGYRFQAKAKLYPVASLF 862
A SYS E L V D +E + D R Y+ D+ + Q+K K + V L
Sbjct: 612 ADSYSEESDSDLSDVPELDSDIEQEAQINYD---RQVYKEDLPQLKQQSKEKNHAVPFLK 668
Query: 863 TQKRRKDDMELSDLHG 878
+K +D ++L +HG
Sbjct: 669 REKAPEDSLKLQFIHG 684
>gi|13346498 WW domain containing transcription regulator 1 [Homo
sapiens]
Length = 400
Score = 30.4 bits (67), Expect = 7.5
Identities = 31/103 (30%), Positives = 47/103 (45%), Gaps = 14/103 (13%)
Query: 304 GFEKNPKPIFTEGKNQ--LEIQNLQEDWDHF----EPLL---SSLLRRMP-ELETLEIMK 353
G P + T+ + Q L +Q +Q + + E L+ ++L R++P E ETL ++
Sbjct: 217 GLMSMPNALTTQQQQQQKLRLQRIQMERERIRMRQEELMRQEAALCRQLPMEAETLAPVQ 276
Query: 354 LVNCPETFTPDMRCIMGES--PAVQG--YFVLAGMNSAGLSFG 392
P T TPDMR I S P + G Y +GL G
Sbjct: 277 AAVNPPTMTPDMRSITNNSSDPFLNGGPYHSREQSTDSGLGLG 319
>gi|239743164 PREDICTED: hypothetical protein [Homo sapiens]
Length = 222
Score = 30.0 bits (66), Expect = 9.8
Identities = 13/29 (44%), Positives = 17/29 (58%)
Query: 11 GRQRASPGWQNWSSARNSTSAAEARSMAL 39
GRQ A PG +W S+ S AAE++ L
Sbjct: 55 GRQEAGPGEADWRSSSESAEAAESQKWGL 83
>gi|239508826 PREDICTED: hypothetical protein [Homo sapiens]
Length = 222
Score = 30.0 bits (66), Expect = 9.8
Identities = 13/29 (44%), Positives = 17/29 (58%)
Query: 11 GRQRASPGWQNWSSARNSTSAAEARSMAL 39
GRQ A PG +W S+ S AAE++ L
Sbjct: 55 GRQEAGPGEADWRSSSESAEAAESQKWGL 83
>gi|52218858 olfactory receptor, family 13, subfamily F, member 1
[Homo sapiens]
Length = 319
Score = 30.0 bits (66), Expect = 9.8
Identities = 19/70 (27%), Positives = 31/70 (44%), Gaps = 4/70 (5%)
Query: 237 FVNCAGQWAYELGLSNEEPVSIPLHACEHFYLLTRPLETPLQSSTPTIVDADGRIYIRNW 296
F CA Q L + + E V +P+ A + + + PL P+ + T V +I +W
Sbjct: 94 FSGCATQMYLSLAMGSTECVLLPMMAYDRYVAICNPLRYPVIMNRRTCV----QIAAGSW 149
Query: 297 QGGILSGGFE 306
G L+ E
Sbjct: 150 MTGCLTAMVE 159
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,891,490
Number of Sequences: 37866
Number of extensions: 1475493
Number of successful extensions: 3055
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 3006
Number of HSP's gapped (non-prelim): 26
length of query: 879
length of database: 18,247,518
effective HSP length: 111
effective length of query: 768
effective length of database: 14,044,392
effective search space: 10786093056
effective search space used: 10786093056
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.