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Search of human proteins with 194306539
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|194306539 anoctamin 1, calcium activated chloride channel
[Homo sapiens]
(986 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|194306539 anoctamin 1, calcium activated chloride channel [Ho... 2010 0.0
gi|209862785 anoctamin 2 [Homo sapiens] 1161 0.0
gi|218084958 anoctamin 4 [Homo sapiens] 687 0.0
gi|156766084 transmembrane protein 16C [Homo sapiens] 639 0.0
gi|218081589 anoctamin 5 isoform b [Homo sapiens] 631 0.0
gi|47106048 anoctamin 5 isoform a [Homo sapiens] 631 0.0
gi|218156303 anoctamin 6 isoform b [Homo sapiens] 582 e-166
gi|218156299 anoctamin 6 isoform a [Homo sapiens] 582 e-166
gi|218156307 anoctamin 6 isoform c [Homo sapiens] 563 e-160
gi|218156305 anoctamin 6 isoform c [Homo sapiens] 563 e-160
gi|145207958 transmembrane protein 16G isoform NGEP long [Homo s... 542 e-154
gi|145611446 tumor protein p53 inducible protein 5 [Homo sapiens] 416 e-116
gi|94536803 transmembrane protein 16K [Homo sapiens] 129 2e-29
gi|55741655 anoctamin 8 [Homo sapiens] 89 2e-17
gi|239741065 PREDICTED: hypothetical protein [Homo sapiens] 79 2e-14
gi|169161033 PREDICTED: hypothetical protein [Homo sapiens] 78 4e-14
gi|239747244 PREDICTED: hypothetical protein [Homo sapiens] 78 4e-14
gi|221219020 NYD-SP11 protein [Homo sapiens] 34 0.77
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 34 0.77
gi|31542760 hypothetical protein LOC220108 [Homo sapiens] 33 1.3
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 32 2.2
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 32 2.2
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 32 2.2
gi|222831595 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 [Homo sap... 32 2.9
gi|148746195 trichohyalin [Homo sapiens] 31 6.5
gi|8923243 palmdelphin [Homo sapiens] 31 6.5
gi|32129212 zinc finger protein 434 [Homo sapiens] 31 6.5
gi|237858799 adenylate kinase domain containing 1 isoform 1 [Hom... 30 8.5
gi|11225260 DNA topoisomerase I [Homo sapiens] 30 8.5
gi|145386566 zinc finger protein 148 [Homo sapiens] 30 8.5
>gi|194306539 anoctamin 1, calcium activated chloride channel [Homo
sapiens]
Length = 986
Score = 2010 bits (5208), Expect = 0.0
Identities = 986/986 (100%), Positives = 986/986 (100%)
Query: 1 MRVNEKYSTLPAEDRSVHIINICAIEDIGYLPSEGTLLNSLSVDPDAECKYGLYFRDGRR 60
MRVNEKYSTLPAEDRSVHIINICAIEDIGYLPSEGTLLNSLSVDPDAECKYGLYFRDGRR
Sbjct: 1 MRVNEKYSTLPAEDRSVHIINICAIEDIGYLPSEGTLLNSLSVDPDAECKYGLYFRDGRR 60
Query: 61 KVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYH 120
KVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYH
Sbjct: 61 KVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYH 120
Query: 121 EDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKK 180
EDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKK
Sbjct: 121 EDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKK 180
Query: 181 MYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSF 240
MYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSF
Sbjct: 181 MYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSF 240
Query: 241 FDSKTRSTIVYEILKRTTCTKAKYSMGITSLLANGVYAAAYPLHDGDYNGENVEFNDRKL 300
FDSKTRSTIVYEILKRTTCTKAKYSMGITSLLANGVYAAAYPLHDGDYNGENVEFNDRKL
Sbjct: 241 FDSKTRSTIVYEILKRTTCTKAKYSMGITSLLANGVYAAAYPLHDGDYNGENVEFNDRKL 300
Query: 301 LYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLIPASIVGIIVFLYGCATM 360
LYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLIPASIVGIIVFLYGCATM
Sbjct: 301 LYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLIPASIVGIIVFLYGCATM 360
Query: 361 DENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWA 420
DENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWA
Sbjct: 361 DENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWA 420
Query: 421 ATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKEKRRHI 480
ATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKEKRRHI
Sbjct: 421 ATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKEKRRHI 480
Query: 481 PEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIY 540
PEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIY
Sbjct: 481 PEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIY 540
Query: 541 RISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEK 600
RISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEK
Sbjct: 541 RISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEK 600
Query: 601 SFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMEL 660
SFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMEL
Sbjct: 601 SFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMEL 660
Query: 661 CIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLE 720
CIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLE
Sbjct: 661 CIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLE 720
Query: 721 PFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRA 780
PFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRA
Sbjct: 721 PFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRA 780
Query: 781 KDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNV 840
KDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNV
Sbjct: 781 KDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNV 840
Query: 841 SDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNL 900
SDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNL
Sbjct: 841 SDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNL 900
Query: 901 VMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDEPPC 960
VMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDEPPC
Sbjct: 901 VMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDEPPC 960
Query: 961 NHHNTKACPDSLGSPAPSHAYHGGVL 986
NHHNTKACPDSLGSPAPSHAYHGGVL
Sbjct: 961 NHHNTKACPDSLGSPAPSHAYHGGVL 986
>gi|209862785 anoctamin 2 [Homo sapiens]
Length = 998
Score = 1161 bits (3004), Expect = 0.0
Identities = 563/894 (62%), Positives = 701/894 (78%), Gaps = 22/894 (2%)
Query: 53 LYFRDGRRKVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGS 112
++F D +RKVDY+L YH+++ + S + K+ H G ++ G
Sbjct: 86 MHFHDSQRKVDYVLAYHYRKRGVHLAQGFPGHSLAIVSNGETGKEPHA--GGPGDIELG- 142
Query: 113 GEPPMDYHEDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFL 172
P+D E++++ +REE+E NL+EAGLELE+D + K G FV+IHAPW VL REAEFL
Sbjct: 143 ---PLDALEEERKEQREEFEHNLMEAGLELEKDLENKSQGSIFVRIHAPWQVLAREAEFL 199
Query: 173 KLKMPTKKMYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLF 232
K+K+PTKKMY I + KK ++ LQK++ +QP+V EH MK LSYPFSREK +L+
Sbjct: 200 KIKVPTKKMYEIKAGGSIAKKFSAALQKLSSHLQPRVPEHSNNKMKNLSYPFSREKMYLY 259
Query: 233 DLSDKDSFFDSKTRSTIVYEILKRTTCTKAKYSMGITSLLANGVYAAAYPLHDGDYNGEN 292
++ +KD+FFD+ TRS IV+EILKRT C++A +MGI SL+AN +Y AAYPLHDG+Y+
Sbjct: 260 NIQEKDTFFDNATRSRIVHEILKRTACSRANNTMGINSLIANNIYEAAYPLHDGEYDSPE 319
Query: 293 VEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLIPASIVGIIV 352
+ NDRKLLY+EWARYGVFYK+QPIDL+RKYFGEKIGLYFAWLG+YT LIP+S++G+IV
Sbjct: 320 DDMNDRKLLYQEWARYGVFYKFQPIDLIRKYFGEKIGLYFAWLGLYTSFLIPSSVIGVIV 379
Query: 353 FLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFF 412
FLYGCAT++E+IPS EMCDQ++ TMCPLCDK+C YW +SSAC TA+ASHLFDNPATVFF
Sbjct: 380 FLYGCATIEEDIPSREMCDQQNAFTMCPLCDKSCDYWNLSSACGTAQASHLFDNPATVFF 439
Query: 413 SVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESR 472
S+FMALWA F+E+WKR QMRL Y WDLTG EEEEE ++H R EYE +V EK LK+ ++
Sbjct: 440 SIFMALWATMFLENWKRLQMRLGYFWDLTGIEEEEERAQEHSRPEYETKVREKMLKESNQ 499
Query: 473 NKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLTNLVSIIFMIAVTFA 532
+ + K T G + D+ KLTW+DRFP YL N SI+FMIA+TF+
Sbjct: 500 SAVQ------------KLETNTTECGDE-DDEDKLTWKDRFPGYLMNFASILFMIALTFS 546
Query: 533 IVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTK 592
IV GVI+YRI+ AAAL++N + RSN+RVTVTATAVIINLVVI++LDE+YG +A+WLTK
Sbjct: 547 IVFGVIVYRITTAAALSLNK--ATRSNVRVTVTATAVIINLVVILILDEIYGAVAKWLTK 604
Query: 593 IEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECA 652
IEVPKTE++FEERLI KAFLLKFVN+Y+PIFYVAFFKGRFVGRPG YVY+F +RMEECA
Sbjct: 605 IEVPKTEQTFEERLILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRMEECA 664
Query: 653 PGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQR 712
PGGCLMELCIQLSIIMLGKQLIQNN+FEIG+PK+KKL R LK + ++ K ++
Sbjct: 665 PGGCLMELCIQLSIIMLGKQLIQNNIFEIGVPKLKKLFRKLKDETEAGETDSAHSKHPEQ 724
Query: 713 YEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTEL 772
+++DY+LEP+ GLTPEYMEMIIQFGFVTLFVASFPLAP+FALLNN+IE+RLDAKKFVTEL
Sbjct: 725 WDLDYSLEPYTGLTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKFVTEL 784
Query: 773 RRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVN 832
RRP AVR KDIGIW++IL GIGK +VI NAFVI+ TSDFIPRLVY Y YS NGT+HGFVN
Sbjct: 785 RRPDAVRTKDIGIWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSYSHNGTLHGFVN 844
Query: 833 HTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLA 892
HTLS FNVS + GT P + EVQ CR+KDYREPPW+ N Y+ SK +W +L+ARLA
Sbjct: 845 HTLSFFNVSQLKEGTQPENS-QFDQEVQFCRFKDYREPPWAPNPYEFSKQYWFILSARLA 903
Query: 893 FVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLE 946
FVI+FQNLVMF+S VDW+IPDIP DIS QI KEK L+V+ F++EE +K +L++
Sbjct: 904 FVIIFQNLVMFLSVLVDWMIPDIPTDISDQIKKEKSLLVDFFLKEEHEKLKLMD 957
>gi|218084958 anoctamin 4 [Homo sapiens]
Length = 920
Score = 687 bits (1772), Expect = 0.0
Identities = 388/944 (41%), Positives = 546/944 (57%), Gaps = 117/944 (12%)
Query: 45 PDAECKYGLYFRDGRRKVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGK 104
P+ GLYFRDG+ ++DYILVY P +
Sbjct: 67 PERNKSNGLYFRDGKCRIDYILVYRKSNPQTEK--------------------------- 99
Query: 105 GASLDAGSGEPPMDYHEDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNV 164
RE +E N+ GL++E++ + FVK+HAPW V
Sbjct: 100 -----------------------REVFERNIRAEGLQMEKESSLINSDIIFVKLHAPWEV 136
Query: 165 LCREAEFLKLKMP-TKKMYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRL--- 220
L R AE + ++MP +K+Y++ + +I+ + + + K +T+ L
Sbjct: 137 LGRYAEQMNVRMPFRRKIYYLPRRYKFMSRIDKQISRFRRWLPKKPMRLDKETLPDLEEN 196
Query: 221 ---SYPFSREKQHLFDLSDKDSFFDSKTRSTIVYEILKRTTCTKAKYSMGITSLLANGVY 277
+ PFS+++ H F + +K++FF++ TRS IV+ IL+R + K +G+ LL NG Y
Sbjct: 197 DCYTAPFSQQRIHHFIIHNKETFFNNATRSRIVHHILQRIKYEEGKNKIGLNRLLTNGSY 256
Query: 278 AAAYPLHDGDYNGENV-----EFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYF 332
AA+PLH+G Y +N N R LLYE WA +GV+YKYQP+DLVR+YFGEKIGLYF
Sbjct: 257 EAAFPLHEGSYRSKNSIRTHGAENHRHLLYECWASWGVWYKYQPLDLVRRYFGEKIGLYF 316
Query: 333 AWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMS 392
AWLG YT ML PA+ +G+ VFLYG T+D + S E+C Q +I MCP+CDK C + ++S
Sbjct: 317 AWLGWYTGMLFPAAFIGLFVFLYGVTTLDHSQVSKEVC-QATDIIMCPVCDKYCPFMRLS 375
Query: 393 SACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKD 452
+C A+ +HLFDN ATVFF+VFMA+WA F+E WKR++ + Y WDL +EEEEE ++
Sbjct: 376 DSCVYAKVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEEEIRP 435
Query: 453 HPRAEYEARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDR 512
A+Y KKE N + P ++ + D+
Sbjct: 436 QFEAKYS--------KKERMNPISGKPEPYQA------------------------FTDK 463
Query: 513 FPAYLTNLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIIN 572
+ + I FMI V A V G++IYR+ + A +R+N +V T TAV IN
Sbjct: 464 CSRLIVSASGIFFMICVVIAAVFGIVIYRVVTVSTFAAFKWALIRNNSQVATTGTAVCIN 523
Query: 573 LVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRF 632
+I+LL+ +Y +A LT +E P+TE +E K FL +FVN + FY+AFF GRF
Sbjct: 524 FCIIMLLNVLYEKVALLLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRF 583
Query: 633 VGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRY 692
G PG Y+ + +R+EEC P GCL++LC+Q+ IIM+ KQ NN E+G P ++
Sbjct: 584 TGHPGAYLRLINRWRLEECHPSGCLIDLCMQMGIIMVLKQT-WNNFMELGYPLIQNWWTR 642
Query: 693 LKLKQQSPPDHEECVKRKQRYEVDYNLEPFA--GLTPEYMEMIIQFGFVTLFVASFPLAP 750
K++Q+ P+ + + +E DYNL+P GL EY+EMI+QFGF T+FVA+FPLAP
Sbjct: 643 RKVRQEHGPERKISFPQ---WEKDYNLQPMNAYGLFDEYLEMILQFGFTTIFVAAFPLAP 699
Query: 751 LFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSD 810
L ALLNNIIEIRLDA KFVT+ RRP+A RAKDIGIWY IL GIG L+VI NAFVI+ TSD
Sbjct: 700 LLALLNNIIEIRLDAYKFVTQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAITSD 759
Query: 811 FIPRLVYLYMY--------SKNGTMHGFVNHTLSSFNVSDFQNGTAP-NDPLDL-GYEVQ 860
FIPRLVY Y Y + M G+VN +LS F +SDF+N + P +D + G ++
Sbjct: 760 FIPRLVYAYKYGPCAGQGEAGQKCMVGYVNASLSVFRISDFENRSEPESDGSEFSGTPLK 819
Query: 861 ICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDIS 920
CRY+DYR+PP S Y + FW VLAARLAF+IVF++LV + + ++IPD+PKD+
Sbjct: 820 YCRYRDYRDPPHSLVPYGYTLQFWHVLAARLAFIIVFEHLVFCIKHLISYLIPDLPKDLR 879
Query: 921 QQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDEPPCNHHN 964
++ +EK L+ E+ E ++ Q KER+K+ HHN
Sbjct: 880 DRMRREKYLIQEMMYEAELERLQK----ERKERKKNGKA--HHN 917
>gi|156766084 transmembrane protein 16C [Homo sapiens]
Length = 981
Score = 639 bits (1647), Expect = 0.0
Identities = 358/858 (41%), Positives = 511/858 (59%), Gaps = 80/858 (9%)
Query: 127 RREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMP-TKKMYHIN 185
+R +E NL GL LE++ + F+KIH PW+ LC+ AE L ++MP KK Y+ +
Sbjct: 179 KRNTFEKNLRAEGLMLEKEPAIASPDIMFIKIHIPWDTLCKYAERLNIRMPFRKKCYYTD 238
Query: 186 ETRGLLKKINSVLQKITDPI--QPKVAEHR--PQTMKRLSY--PFSREKQHLFDLSDKDS 239
+ ++ + ++I + + P V + P + Y PFSR + H F +++KD+
Sbjct: 239 GRSKSMGRMQTYFRRIKNWMAQNPMVLDKSAFPDLEESDCYTGPFSRARIHHFIINNKDT 298
Query: 240 FFDSKTRSTIVYEILKRTTCTKAKYSMGITSLLANGVYAAAYPLHDGDYNGENV-----E 294
FF + TRS IVY +L+RT +GI L+ NG Y AA+P H+G Y
Sbjct: 299 FFSNATRSRIVYHMLERTKYENGISKVGIRKLINNGSYIAAFPPHEGAYKSSQPIKTHGP 358
Query: 295 FNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLIPASIVGIIVFL 354
N+R LLYE WAR+G++YK+QP+DL+R YFGEKIGLYFAWLG YT MLIPA+IVG+ VF
Sbjct: 359 QNNRHLLYERWARWGMWYKHQPLDLIRLYFGEKIGLYFAWLGWYTGMLIPAAIVGLCVFF 418
Query: 355 YGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSV 414
YG TM+ + S E+C + + MCPLCDK CS +++ +C A+ ++LFDN TVFF++
Sbjct: 419 YGLFTMNNSQVSQEIC-KATEVFMCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFAI 477
Query: 415 FMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNK 474
FMA+WA F+E WKR++ L Y WDL +EEEEE + R ++EA K K E N
Sbjct: 478 FMAIWATVFLEFWKRRRSILTYTWDLIEWEEEEETL----RPQFEA----KYYKMEIVNP 529
Query: 475 EKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIV 534
+ P + ++ D+ L ++ I FMI++ V
Sbjct: 530 ITGKPEPHQPSS------------------------DKVTRLLVSVSGIFFMISLVITAV 565
Query: 535 LGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIE 594
GV++YR+ + A ++ + +A AV IN ++I+LL+ Y IA LT +E
Sbjct: 566 FGVVVYRLVVMEQFASFKWNFIKQYWQFATSAAAVCINFIIIMLLNLAYEKIAYLLTNLE 625
Query: 595 VPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPG 654
P+TE +E K FL +FVN + IFY+AFF GRFVG PG Y +F +R+EEC P
Sbjct: 626 YPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYNKLFDRWRLEECHPS 685
Query: 655 GCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYE 714
GCL++LC+Q+ +IM KQ I NN E+G P ++ K+K+ H+ + + +E
Sbjct: 686 GCLIDLCLQMGVIMFLKQ-IWNNFMELGYPLIQNWWSRHKIKRGI---HDASIPQ---WE 738
Query: 715 VDYNLEPFA--GLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTEL 772
D+NL+P GL EY+EM++QFGF T+FVA+FPLAPL ALLNNIIEIRLDA KFVT+
Sbjct: 739 NDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQW 798
Query: 773 RRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYS--------KN 824
RRP+ RA DIGIW IL GIG LAVI NAFVI+ TSD+IPR VY Y Y
Sbjct: 799 RRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPSE 858
Query: 825 GTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFW 884
+ G+VN++LS F++S+ G + GY CRY+DYR PPWS Y+ + +W
Sbjct: 859 NCLKGYVNNSLSFFDLSELGMGKS-------GY----CRYRDYRGPPWSSKPYEFTLQYW 907
Query: 885 AVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQL 944
+LAARLAF+IVF++LV + F+ ++IPD+PK + +I +EK L+ E+ E +
Sbjct: 908 HILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMYEAELEH--- 964
Query: 945 LETWMEKERQKDEPPCNH 962
++++R+K P +H
Sbjct: 965 ----LQQQRRKSGQPVHH 978
>gi|218081589 anoctamin 5 isoform b [Homo sapiens]
Length = 912
Score = 631 bits (1628), Expect = 0.0
Identities = 367/925 (39%), Positives = 526/925 (56%), Gaps = 116/925 (12%)
Query: 37 LLNSLSVDPDAECKYGLYFRDGRRKVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVK 96
L L + + K ++FRDG R++D++L Y VK
Sbjct: 54 LRRRLMFQKNQQSKDSIFFRDGIRQIDFVLSY-----------------------VDDVK 90
Query: 97 QDHPLPGKGASLDAGSGEPPMDYHEDDKRFRREEYEGNLLEAGLELERDE--DTKIHGVG 154
+D L K RR+E+E NL + GLELE ++ D++
Sbjct: 91 KDAEL----------------------KAERRKEFETNLRKTGLELEIEDKRDSEDGRTY 128
Query: 155 FVKIHAPWNVLCREAEFLKLKMPTKKMYHINETRGLLKKINSVLQKITDPIQPKVAEHRP 214
FVKIHAPW VL AE L +KMP K+ + R I+ VL + P+ K
Sbjct: 129 FVKIHAPWEVLVTYAEVLGIKMPIKES---DIPRPKHTPISYVLGPVRLPLSVKYPHPEY 185
Query: 215 QTMKRLSYPFSREKQHLFDLSDKDSFFDSKTRSTIVYEILKRTT--CTKAKYSMGITSLL 272
T + FSR +Q LF + D+ +FF S +R+ IVY IL R K GI LL
Sbjct: 186 FTAQ-----FSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIEDGKKRFGIERLL 240
Query: 273 ANGVYAAAYPLHDGDY---NGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIG 329
+ Y++AYPLHDG Y + N+R L++ WAR+ FYK QP+DL++ Y+GEKIG
Sbjct: 241 NSNTYSSAYPLHDGQYWKPSEPPNPTNERYTLHQNWARFSYFYKEQPLDLIKNYYGEKIG 300
Query: 330 LYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQR--HNITMCPLCDKTCS 387
+YF +LG YT+ML A++VG+ F+YG +M+ N S E+CD + MCPLCD+ C
Sbjct: 301 IYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPLCDQVCD 360
Query: 388 YWKMSSACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEE 447
YW+++S C ++ SHLFDN +TVFF++FM +W F+E WK++Q RL Y WDL FEEE+
Sbjct: 361 YWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEEQ 420
Query: 448 EAVKDHPRAEYEARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKL 507
+ ++ P E+EA + K K + KE ++P +
Sbjct: 421 QQLQLRP--EFEA--MCKHRKLNAVTKEMEPYMPLYT----------------------- 453
Query: 508 TWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIYRISMAAALA--MNSSPSVRS-----NI 560
R P Y + ++ +++ ++ VI+YR+S+ A A M S S++
Sbjct: 454 ----RIPWYFLSGATVTLWMSLVVTSMVAVIVYRLSVFATFASFMESDASLKQVKSFLTP 509
Query: 561 RVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYT 620
++T + T +N +VI++L+ Y I+ W+TK+E+P+T + +E L K FL +FVN Y+
Sbjct: 510 QITTSLTGSCLNFIVILILNFFYEKISAWITKMEIPRTYQEYESSLTLKMFLFQFVNFYS 569
Query: 621 PIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFE 680
FYVAFFKG+FVG PG Y Y+F +R EEC PGGCL+EL QL+IIM GKQ+ N+ E
Sbjct: 570 SCFYVAFFKGKFVGYPGKYTYLFNEWRSEECDPGGCLIELTTQLTIIMTGKQIF-GNIKE 628
Query: 681 IGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFA--GLTPEYMEMIIQFGF 738
P R K + S K R+E D++LE F GL EY+E + QFGF
Sbjct: 629 AIYPLALNWWRRRKARTNSE-------KLYSRWEQDHDLESFGPLGLFYEYLETVTQFGF 681
Query: 739 VTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAV 798
VTLFVASFPLAPL AL+NNI+EIR+DA K T+ RR VA +A IG+W +IL G+ L+V
Sbjct: 682 VTLFVASFPLAPLLALINNIVEIRVDAWKLTTQYRRTVASKAHSIGVWQDILYGMAVLSV 741
Query: 799 IINAFVISFTSDFIPRLVYLYMYSKNGT--MHGFVNHTLSSFNVSDFQNGTAPNDPLDLG 856
NAF+++FTSD IPRLVY Y YS N T M G+VN++LS F ++DF N TAP++ D
Sbjct: 742 ATNAFIVAFTSDIIPRLVYYYAYSTNATQPMTGYVNNSLSVFLIADFPNHTAPSEKRDF- 800
Query: 857 YEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIP 916
CRY+DYR PP ENKY + FW VLAA++ F+IV +++V + + W+IPD+P
Sbjct: 801 ---ITCRYRDYRYPPDDENKYFHNMQFWHVLAAKMTFIIVMEHVVFLVKFLLAWMIPDVP 857
Query: 917 KDISQQIHKEKVLMVELFMREEQDK 941
KD+ ++I +EK++ +++ E +K
Sbjct: 858 KDVVERIKREKLMTIKILHDFELNK 882
>gi|47106048 anoctamin 5 isoform a [Homo sapiens]
Length = 913
Score = 631 bits (1628), Expect = 0.0
Identities = 367/925 (39%), Positives = 526/925 (56%), Gaps = 116/925 (12%)
Query: 37 LLNSLSVDPDAECKYGLYFRDGRRKVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVK 96
L L + + K ++FRDG R++D++L Y VK
Sbjct: 55 LRRRLMFQKNQQSKDSIFFRDGIRQIDFVLSY-----------------------VDDVK 91
Query: 97 QDHPLPGKGASLDAGSGEPPMDYHEDDKRFRREEYEGNLLEAGLELERDE--DTKIHGVG 154
+D L K RR+E+E NL + GLELE ++ D++
Sbjct: 92 KDAEL----------------------KAERRKEFETNLRKTGLELEIEDKRDSEDGRTY 129
Query: 155 FVKIHAPWNVLCREAEFLKLKMPTKKMYHINETRGLLKKINSVLQKITDPIQPKVAEHRP 214
FVKIHAPW VL AE L +KMP K+ + R I+ VL + P+ K
Sbjct: 130 FVKIHAPWEVLVTYAEVLGIKMPIKES---DIPRPKHTPISYVLGPVRLPLSVKYPHPEY 186
Query: 215 QTMKRLSYPFSREKQHLFDLSDKDSFFDSKTRSTIVYEILKRTT--CTKAKYSMGITSLL 272
T + FSR +Q LF + D+ +FF S +R+ IVY IL R K GI LL
Sbjct: 187 FTAQ-----FSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIEDGKKRFGIERLL 241
Query: 273 ANGVYAAAYPLHDGDY---NGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIG 329
+ Y++AYPLHDG Y + N+R L++ WAR+ FYK QP+DL++ Y+GEKIG
Sbjct: 242 NSNTYSSAYPLHDGQYWKPSEPPNPTNERYTLHQNWARFSYFYKEQPLDLIKNYYGEKIG 301
Query: 330 LYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQR--HNITMCPLCDKTCS 387
+YF +LG YT+ML A++VG+ F+YG +M+ N S E+CD + MCPLCD+ C
Sbjct: 302 IYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPLCDQVCD 361
Query: 388 YWKMSSACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEE 447
YW+++S C ++ SHLFDN +TVFF++FM +W F+E WK++Q RL Y WDL FEEE+
Sbjct: 362 YWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEEQ 421
Query: 448 EAVKDHPRAEYEARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKL 507
+ ++ P E+EA + K K + KE ++P +
Sbjct: 422 QQLQLRP--EFEA--MCKHRKLNAVTKEMEPYMPLYT----------------------- 454
Query: 508 TWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIYRISMAAALA--MNSSPSVRS-----NI 560
R P Y + ++ +++ ++ VI+YR+S+ A A M S S++
Sbjct: 455 ----RIPWYFLSGATVTLWMSLVVTSMVAVIVYRLSVFATFASFMESDASLKQVKSFLTP 510
Query: 561 RVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYT 620
++T + T +N +VI++L+ Y I+ W+TK+E+P+T + +E L K FL +FVN Y+
Sbjct: 511 QITTSLTGSCLNFIVILILNFFYEKISAWITKMEIPRTYQEYESSLTLKMFLFQFVNFYS 570
Query: 621 PIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFE 680
FYVAFFKG+FVG PG Y Y+F +R EEC PGGCL+EL QL+IIM GKQ+ N+ E
Sbjct: 571 SCFYVAFFKGKFVGYPGKYTYLFNEWRSEECDPGGCLIELTTQLTIIMTGKQIF-GNIKE 629
Query: 681 IGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFA--GLTPEYMEMIIQFGF 738
P R K + S K R+E D++LE F GL EY+E + QFGF
Sbjct: 630 AIYPLALNWWRRRKARTNSE-------KLYSRWEQDHDLESFGPLGLFYEYLETVTQFGF 682
Query: 739 VTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAV 798
VTLFVASFPLAPL AL+NNI+EIR+DA K T+ RR VA +A IG+W +IL G+ L+V
Sbjct: 683 VTLFVASFPLAPLLALINNIVEIRVDAWKLTTQYRRTVASKAHSIGVWQDILYGMAVLSV 742
Query: 799 IINAFVISFTSDFIPRLVYLYMYSKNGT--MHGFVNHTLSSFNVSDFQNGTAPNDPLDLG 856
NAF+++FTSD IPRLVY Y YS N T M G+VN++LS F ++DF N TAP++ D
Sbjct: 743 ATNAFIVAFTSDIIPRLVYYYAYSTNATQPMTGYVNNSLSVFLIADFPNHTAPSEKRDF- 801
Query: 857 YEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIP 916
CRY+DYR PP ENKY + FW VLAA++ F+IV +++V + + W+IPD+P
Sbjct: 802 ---ITCRYRDYRYPPDDENKYFHNMQFWHVLAAKMTFIIVMEHVVFLVKFLLAWMIPDVP 858
Query: 917 KDISQQIHKEKVLMVELFMREEQDK 941
KD+ ++I +EK++ +++ E +K
Sbjct: 859 KDVVERIKREKLMTIKILHDFELNK 883
>gi|218156303 anoctamin 6 isoform b [Homo sapiens]
Length = 892
Score = 582 bits (1500), Expect = e-166
Identities = 345/913 (37%), Positives = 509/913 (55%), Gaps = 127/913 (13%)
Query: 53 LYFRDGRRKVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGS 112
L+F DG+R++D++LVY + +T + KQ
Sbjct: 42 LFFNDGQRRIDFVLVYEDE------------SRKETNKKGTNEKQ--------------- 74
Query: 113 GEPPMDYHEDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFL 172
R +R+ YE NL+ GL+LE + FVK+HAPW VLC AE +
Sbjct: 75 ------------RRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIM 122
Query: 173 KLKMPTKK--MYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQH 230
+K+P K + + + G L VL I+P+ + + PF + + +
Sbjct: 123 HIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPE--------QEFFTAPFEKNRMN 174
Query: 231 LFDLSDKDSFFDSKTRSTIVYEILKRTTCTKAKYSM-------GITSLLANGVYAAAYPL 283
F + D+D+FF+ TRS IVY IL R KY + GI L+ +G+Y AA+PL
Sbjct: 175 DFYIVDRDAFFNPATRSRIVYFILSRV-----KYQVINNVSKFGINRLVNSGIYKAAFPL 229
Query: 284 HDGDYNGENVEF---NDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQ 340
HD + ++ + N+R LLY EWA YK QP+DL+RKY+GEKIG+YFAWLG YTQ
Sbjct: 230 HDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQ 289
Query: 341 MLIPASIVGIIVFLYGCATMDENIPSMEMC--DQRHNITMCPLCDKTCSYWKMSSACATA 398
ML+ A++VG+ FLYG D S E+C D I MCP CD+ C +WK++ C ++
Sbjct: 290 MLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESS 349
Query: 399 RASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEY 458
+ +FD+ T+ F+VFM +W F+E WKR+Q L Y WD ++EE+A R EY
Sbjct: 350 KKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQA-----RPEY 404
Query: 459 EARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLT 518
EAR + + ++ +E+ IP W + ++ +
Sbjct: 405 EARCTHVVINEITQEEER---IP---FTAWGKCIRITLCA-------------------- 438
Query: 519 NLVSIIFMIAVTFAIVLGVIIYRISMAAALA------MNSSPSVRSNI--RVTVTATAVI 570
++ F I + A V+G+I+YR+S+ + +N + ++ + + + TA I
Sbjct: 439 --SAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASI 496
Query: 571 INLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKG 630
I+ ++I++L+ +Y +A +T E+P+T+ +E L K FL +FVN Y+ FY+AFFKG
Sbjct: 497 ISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKG 556
Query: 631 RFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLI 690
+FVG PGD VY +R EEC PGGCL+EL QL+IIM GK I NN+ E+ +P + LI
Sbjct: 557 KFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGK-AIWNNIQEVLLPWIMNLI 615
Query: 691 -RYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFA--GLTPEYMEMIIQFGFVTLFVASFP 747
R+ ++ K R+E DY+L+P GL EY+EMIIQFGFVTLFVASFP
Sbjct: 616 GRFHRVSGSE--------KITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFP 667
Query: 748 LAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISF 807
LAPL AL+NNI+EIR+DA K T+ RR V +A+DIG W I++GI LAV+ NA +I+F
Sbjct: 668 LAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAF 727
Query: 808 TSDFIPRLVYLYMYS-------KNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQ 860
TSD IPRLVY + +S + TM G++N+TLS F V+DF+N + N DLG
Sbjct: 728 TSDMIPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHT- 786
Query: 861 ICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDIS 920
CRY+D+R PP +Y + +W V+AA+LAF+IV ++++ + F+ + IPD+ K
Sbjct: 787 TCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPDVSKRTK 846
Query: 921 QQIHKEKVLMVEL 933
+I +EK L +L
Sbjct: 847 SKIQREKYLTQKL 859
>gi|218156299 anoctamin 6 isoform a [Homo sapiens]
Length = 910
Score = 582 bits (1500), Expect = e-166
Identities = 345/913 (37%), Positives = 509/913 (55%), Gaps = 127/913 (13%)
Query: 53 LYFRDGRRKVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGS 112
L+F DG+R++D++LVY + +T + KQ
Sbjct: 60 LFFNDGQRRIDFVLVYEDE------------SRKETNKKGTNEKQ--------------- 92
Query: 113 GEPPMDYHEDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFL 172
R +R+ YE NL+ GL+LE + FVK+HAPW VLC AE +
Sbjct: 93 ------------RRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIM 140
Query: 173 KLKMPTKK--MYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQH 230
+K+P K + + + G L VL I+P+ + + PF + + +
Sbjct: 141 HIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPE--------QEFFTAPFEKNRMN 192
Query: 231 LFDLSDKDSFFDSKTRSTIVYEILKRTTCTKAKYSM-------GITSLLANGVYAAAYPL 283
F + D+D+FF+ TRS IVY IL R KY + GI L+ +G+Y AA+PL
Sbjct: 193 DFYIVDRDAFFNPATRSRIVYFILSRV-----KYQVINNVSKFGINRLVNSGIYKAAFPL 247
Query: 284 HDGDYNGENVEF---NDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQ 340
HD + ++ + N+R LLY EWA YK QP+DL+RKY+GEKIG+YFAWLG YTQ
Sbjct: 248 HDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQ 307
Query: 341 MLIPASIVGIIVFLYGCATMDENIPSMEMC--DQRHNITMCPLCDKTCSYWKMSSACATA 398
ML+ A++VG+ FLYG D S E+C D I MCP CD+ C +WK++ C ++
Sbjct: 308 MLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESS 367
Query: 399 RASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEY 458
+ +FD+ T+ F+VFM +W F+E WKR+Q L Y WD ++EE+A R EY
Sbjct: 368 KKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQA-----RPEY 422
Query: 459 EARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLT 518
EAR + + ++ +E+ IP W + ++ +
Sbjct: 423 EARCTHVVINEITQEEER---IP---FTAWGKCIRITLCA-------------------- 456
Query: 519 NLVSIIFMIAVTFAIVLGVIIYRISMAAALA------MNSSPSVRSNI--RVTVTATAVI 570
++ F I + A V+G+I+YR+S+ + +N + ++ + + + TA I
Sbjct: 457 --SAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASI 514
Query: 571 INLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKG 630
I+ ++I++L+ +Y +A +T E+P+T+ +E L K FL +FVN Y+ FY+AFFKG
Sbjct: 515 ISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKG 574
Query: 631 RFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLI 690
+FVG PGD VY +R EEC PGGCL+EL QL+IIM GK I NN+ E+ +P + LI
Sbjct: 575 KFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGK-AIWNNIQEVLLPWIMNLI 633
Query: 691 -RYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFA--GLTPEYMEMIIQFGFVTLFVASFP 747
R+ ++ K R+E DY+L+P GL EY+EMIIQFGFVTLFVASFP
Sbjct: 634 GRFHRVSGSE--------KITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFP 685
Query: 748 LAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISF 807
LAPL AL+NNI+EIR+DA K T+ RR V +A+DIG W I++GI LAV+ NA +I+F
Sbjct: 686 LAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAF 745
Query: 808 TSDFIPRLVYLYMYS-------KNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQ 860
TSD IPRLVY + +S + TM G++N+TLS F V+DF+N + N DLG
Sbjct: 746 TSDMIPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHT- 804
Query: 861 ICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDIS 920
CRY+D+R PP +Y + +W V+AA+LAF+IV ++++ + F+ + IPD+ K
Sbjct: 805 TCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPDVSKRTK 864
Query: 921 QQIHKEKVLMVEL 933
+I +EK L +L
Sbjct: 865 SKIQREKYLTQKL 877
>gi|218156307 anoctamin 6 isoform c [Homo sapiens]
Length = 929
Score = 563 bits (1450), Expect = e-160
Identities = 336/882 (38%), Positives = 491/882 (55%), Gaps = 127/882 (14%)
Query: 53 LYFRDGRRKVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGS 112
L+F DG+R++D++LVY + +T + KQ
Sbjct: 60 LFFNDGQRRIDFVLVYEDE------------SRKETNKKGTNEKQ--------------- 92
Query: 113 GEPPMDYHEDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFL 172
R +R+ YE NL+ GL+LE + FVK+HAPW VLC AE +
Sbjct: 93 ------------RRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIM 140
Query: 173 KLKMPTKK--MYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQH 230
+K+P K + + + G L VL I+P+ + + PF + + +
Sbjct: 141 HIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPE--------QEFFTAPFEKNRMN 192
Query: 231 LFDLSDKDSFFDSKTRSTIVYEILKRTTCTKAKYSM-------GITSLLANGVYAAAYPL 283
F + D+D+FF+ TRS IVY IL R KY + GI L+ +G+Y AA+PL
Sbjct: 193 DFYIVDRDAFFNPATRSRIVYFILSRV-----KYQVINNVSKFGINRLVNSGIYKAAFPL 247
Query: 284 HDGDYNGENVEF---NDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQ 340
HD + ++ + N+R LLY EWA YK QP+DL+RKY+GEKIG+YFAWLG YTQ
Sbjct: 248 HDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQ 307
Query: 341 MLIPASIVGIIVFLYGCATMDENIPSMEMC--DQRHNITMCPLCDKTCSYWKMSSACATA 398
ML+ A++VG+ FLYG D S E+C D I MCP CD+ C +WK++ C ++
Sbjct: 308 MLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESS 367
Query: 399 RASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEY 458
+ +FD+ T+ F+VFM +W F+E WKR+Q L Y WD ++EE+A R EY
Sbjct: 368 KKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQA-----RPEY 422
Query: 459 EARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLT 518
EAR + + ++ +E+ IP W + ++ +
Sbjct: 423 EARCTHVVINEITQEEER---IP---FTAWGKCIRITLCA-------------------- 456
Query: 519 NLVSIIFMIAVTFAIVLGVIIYRISMAAALA------MNSSPSVRSNI--RVTVTATAVI 570
++ F I + A V+G+I+YR+S+ + +N + ++ + + + TA I
Sbjct: 457 --SAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASI 514
Query: 571 INLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKG 630
I+ ++I++L+ +Y +A +T E+P+T+ +E L K FL +FVN Y+ FY+AFFKG
Sbjct: 515 ISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKG 574
Query: 631 RFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLI 690
+FVG PGD VY +R EEC PGGCL+EL QL+IIM GK I NN+ E+ +P + LI
Sbjct: 575 KFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGK-AIWNNIQEVLLPWIMNLI 633
Query: 691 -RYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFA--GLTPEYMEMIIQFGFVTLFVASFP 747
R+ ++ K R+E DY+L+P GL EY+EMIIQFGFVTLFVASFP
Sbjct: 634 GRFHRVSGSE--------KITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFP 685
Query: 748 LAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISF 807
LAPL AL+NNI+EIR+DA K T+ RR V +A+DIG W I++GI LAV+ NA +I+F
Sbjct: 686 LAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAF 745
Query: 808 TSDFIPRLVYLYMYS-------KNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQ 860
TSD IPRLVY + +S + TM G++N+TLS F V+DF+N + N DLG
Sbjct: 746 TSDMIPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHT- 804
Query: 861 ICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVM 902
CRY+D+R PP +Y + +W V+AA+LAF+IV + L +
Sbjct: 805 TCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMEYLAL 846
>gi|218156305 anoctamin 6 isoform c [Homo sapiens]
Length = 929
Score = 563 bits (1450), Expect = e-160
Identities = 336/882 (38%), Positives = 491/882 (55%), Gaps = 127/882 (14%)
Query: 53 LYFRDGRRKVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGS 112
L+F DG+R++D++LVY + +T + KQ
Sbjct: 60 LFFNDGQRRIDFVLVYEDE------------SRKETNKKGTNEKQ--------------- 92
Query: 113 GEPPMDYHEDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFL 172
R +R+ YE NL+ GL+LE + FVK+HAPW VLC AE +
Sbjct: 93 ------------RRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIM 140
Query: 173 KLKMPTKK--MYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQH 230
+K+P K + + + G L VL I+P+ + + PF + + +
Sbjct: 141 HIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPE--------QEFFTAPFEKNRMN 192
Query: 231 LFDLSDKDSFFDSKTRSTIVYEILKRTTCTKAKYSM-------GITSLLANGVYAAAYPL 283
F + D+D+FF+ TRS IVY IL R KY + GI L+ +G+Y AA+PL
Sbjct: 193 DFYIVDRDAFFNPATRSRIVYFILSRV-----KYQVINNVSKFGINRLVNSGIYKAAFPL 247
Query: 284 HDGDYNGENVEF---NDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQ 340
HD + ++ + N+R LLY EWA YK QP+DL+RKY+GEKIG+YFAWLG YTQ
Sbjct: 248 HDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQ 307
Query: 341 MLIPASIVGIIVFLYGCATMDENIPSMEMC--DQRHNITMCPLCDKTCSYWKMSSACATA 398
ML+ A++VG+ FLYG D S E+C D I MCP CD+ C +WK++ C ++
Sbjct: 308 MLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESS 367
Query: 399 RASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEY 458
+ +FD+ T+ F+VFM +W F+E WKR+Q L Y WD ++EE+A R EY
Sbjct: 368 KKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQA-----RPEY 422
Query: 459 EARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLT 518
EAR + + ++ +E+ IP W + ++ +
Sbjct: 423 EARCTHVVINEITQEEER---IP---FTAWGKCIRITLCA-------------------- 456
Query: 519 NLVSIIFMIAVTFAIVLGVIIYRISMAAALA------MNSSPSVRSNI--RVTVTATAVI 570
++ F I + A V+G+I+YR+S+ + +N + ++ + + + TA I
Sbjct: 457 --SAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASI 514
Query: 571 INLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKG 630
I+ ++I++L+ +Y +A +T E+P+T+ +E L K FL +FVN Y+ FY+AFFKG
Sbjct: 515 ISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKG 574
Query: 631 RFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLI 690
+FVG PGD VY +R EEC PGGCL+EL QL+IIM GK I NN+ E+ +P + LI
Sbjct: 575 KFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGK-AIWNNIQEVLLPWIMNLI 633
Query: 691 -RYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFA--GLTPEYMEMIIQFGFVTLFVASFP 747
R+ ++ K R+E DY+L+P GL EY+EMIIQFGFVTLFVASFP
Sbjct: 634 GRFHRVSGSE--------KITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFP 685
Query: 748 LAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISF 807
LAPL AL+NNI+EIR+DA K T+ RR V +A+DIG W I++GI LAV+ NA +I+F
Sbjct: 686 LAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAF 745
Query: 808 TSDFIPRLVYLYMYS-------KNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQ 860
TSD IPRLVY + +S + TM G++N+TLS F V+DF+N + N DLG
Sbjct: 746 TSDMIPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHT- 804
Query: 861 ICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVM 902
CRY+D+R PP +Y + +W V+AA+LAF+IV + L +
Sbjct: 805 TCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMEYLAL 846
>gi|145207958 transmembrane protein 16G isoform NGEP long [Homo
sapiens]
Length = 933
Score = 542 bits (1396), Expect = e-154
Identities = 324/831 (38%), Positives = 480/831 (57%), Gaps = 81/831 (9%)
Query: 122 DDKRFRREEYEGNLLEAGLELER----DEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMP 177
D R RE + NL AGL +++ D +T +H + + A W VLC AE L+LK+P
Sbjct: 135 DMHRTWRETFLDNLRAAGLCVDQQDVQDGNTTVH---YALLSASWAVLCYYAEDLRLKLP 191
Query: 178 TKKMYH--INETRGLLK--KINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFD 233
+++ + N + GLL I +VL ++ + P+ R + K + S
Sbjct: 192 LQELPNQASNWSAGLLAWLGIPNVLLEVVPDVPPEYYSCRFRVNKLPRFLGS-------- 243
Query: 234 LSDKDSFFDSKTRSTIVYEILKRTTCTKAKYSM-GITSLLANGVYAAAYPLHDGDYNG-- 290
++D+FF S R I++EIL +T K ++ GI LLA GV +AA+PLHDG +
Sbjct: 244 -DNQDTFFTSTKRHQILFEILAKTPYGHEKKNLLGIHQLLAEGVLSAAFPLHDGPFKTPP 302
Query: 291 ---ENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLIPASI 347
+ N R++L++ WAR+G + KYQP+D VR+YFGEK+ LYFAWLG YT L+PA++
Sbjct: 303 EGPQAPRLNQRQVLFQHWARWGKWNKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPAAV 362
Query: 348 VGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNP 407
VG +VFL GC + +IP+ E+C + + MCPLC C +W +SSACA A+A LFD+
Sbjct: 363 VGTLVFLVGCFLVFSDIPTQELCGSKDSFEMCPLC-LDCPFWLLSSACALAQAGRLFDHG 421
Query: 408 ATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSL 467
TVFFS+FMALWA +E+WKRK L YRWD + +E+ EE PR ++ A
Sbjct: 422 GTVFFSLFMALWAVLLLEYWKRKSATLAYRWDCSDYEDTEE----RPRPQFAA------- 470
Query: 468 KKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLTNLVSIIFMI 527
TA + D+ R R L V I+ M+
Sbjct: 471 ----------------------SAPMTAPNPITGEDEPYFPERSRARRMLAGSVVIVVMV 508
Query: 528 AVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIA 587
AV ++ +I+YR MA ++ + + + + + T ++NLV I++L ++Y +A
Sbjct: 509 AVVVMCLVSIILYRAIMAIVVSRSGNTLLAAWASRIASLTGSVVNLVFILILSKIYVSLA 568
Query: 588 RWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFR 647
LT+ E+ +T+ FE+ K F+ +FVN Y+ Y+AFFKGRFVG PG+Y +F R
Sbjct: 569 HVLTRWEMHRTQTKFEDAFTLKVFIFQFVNFYSSPVYIAFFKGRFVGYPGNYHTLF-GVR 627
Query: 648 MEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECV 707
EECA GGCL+EL +L +IM+GKQ+I NN+ E+ IPK+K + +L+ +
Sbjct: 628 NEECAAGGCLIELAQELLVIMVGKQVI-NNMQEVLIPKLKGWWQKFRLRSKKRKAGASAG 686
Query: 708 KRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKK 767
+ +E DY L P GL EY+EM++QFGFVT+FVA+ PLAPLFALLNN +EIRLDA+K
Sbjct: 687 ASQGPWEDDYELVPCEGLFDEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARK 746
Query: 768 FVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTM 827
FV E RRPVA RA+DIGIW++IL G+ LAVI NAF+++F+SDF+PR Y +++ +
Sbjct: 747 FVCEYRRPVAERAQDIGIWFHILAGLTHLAVISNAFLLAFSSDFLPRA--YYRWTRAHDL 804
Query: 828 HGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVL 887
GF+N TL+ AP+ + CRY+ +R+ + Y S+ +W +L
Sbjct: 805 RGFLNFTLA----------RAPSS--FAAAHNRTCRYRAFRD---DDGHY--SQTYWNLL 847
Query: 888 AARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREE 938
A RLAFVIVF+++V + +D ++PDIP+ + ++ +E L + E
Sbjct: 848 AIRLAFVIVFEHVVFSVGRLLDLLVPDIPESVEIKVKREYYLAKQALAENE 898
>gi|145611446 tumor protein p53 inducible protein 5 [Homo sapiens]
Length = 782
Score = 416 bits (1070), Expect = e-116
Identities = 255/724 (35%), Positives = 382/724 (52%), Gaps = 101/724 (13%)
Query: 263 KYSMGIT--SLLANGVYAAAYPLHDGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLV 320
K S G T L+ +GV+ A +PLH G+ L + WAR+ ++ QP+D +
Sbjct: 131 KTSAGETFEDLMKDGVFEARFPLHKGEGR-----------LKKTWARWRHMFREQPVDEI 179
Query: 321 RKYFGEKIGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCP 380
R YFGEK+ LYF WLG YT ML+PA++ G++VFL G + + + S E+C+ H+I MCP
Sbjct: 180 RNYFGEKVALYFVWLGWYTYMLVPAALTGLLVFLSGFSLFEASQISKEICEA-HDILMCP 238
Query: 381 LCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDL 440
L D + Y ++S C A+ +HLFDN TV F++FMALWA F+E WKR++ R+ WDL
Sbjct: 239 LGDHSRRYQRLSETCTFAKLTHLFDNDGTVVFAIFMALWATVFLEIWKRQRARVVLHWDL 298
Query: 441 TGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVK 500
++EE+E + A+ +
Sbjct: 299 YVWDEEQEEM--------------------------------------------ALQLIN 314
Query: 501 LTDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNI 560
D ++ + LV + MI + + +++YR+ +A + ++ P + +
Sbjct: 315 CPDYKLRPYQHSYLRSTVILVLTLLMICLMIGMAHVLVVYRVLASALFSSSAVPFLEEQV 374
Query: 561 RVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYT 620
V T +++ V II++ ++ C+A L E+P+T E R + F L+F ++
Sbjct: 375 TTAVVVTGALVHYVTIIIMTKINRCVALKLCDFEMPRTFSERESRFTIRFFTLQFFTHFS 434
Query: 621 PIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFE 680
+ Y+AF GR G PG + +++EEC GC+M+L +Q++IIM KQ + +N E
Sbjct: 435 SLIYIAFILGRINGHPGKSTRLAGLWKLEECHASGCMMDLFVQMAIIMGLKQTL-SNCVE 493
Query: 681 IGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFA--GLTPEYMEMIIQFGF 738
+P + R L+ + + ++ +R +Y L P L E+MEM+IQ+GF
Sbjct: 494 YLVPWVTHKCRSLRASESGHLPRDPELRDWRR---NYLLNPVNTFSLFDEFMEMMIQYGF 550
Query: 739 VTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAV 798
T+FVA+FPLAPL AL +N++EIRLDA K V RR V +AKDIG W +L IG LAV
Sbjct: 551 TTIFVAAFPLAPLLALFSNLVEIRLDAIKMVWLQRRLVPRKAKDIGTWLQVLETIGVLAV 610
Query: 799 IINAFVISFTSDFIPRLVYLYMYS---KNGT-----MHGFVNHTLSSFNVSDFQNGTAPN 850
I N VI+FTS+FIPR+VY Y YS K G + G+VNH+LS F+ DFQ+
Sbjct: 611 IANGMVIAFTSEFIPRVVYKYRYSPCLKEGNSTVDCLKGYVNHSLSVFHTKDFQD----P 666
Query: 851 DPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDW 910
D ++ V +CRY+DYR PP Y+ S+ FW +LA RLAFVI+F+++ + + W
Sbjct: 667 DGIEGSENVTLCRYRDYRNPP----DYNFSEQFWFLLAIRLAFVILFEHVALCIKLIAAW 722
Query: 911 VIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQK-------DEPPCNHH 963
+PDIP+ + K KVL V K Q L M RQ+ PP H
Sbjct: 723 FVPDIPQSV-----KNKVLEV---------KYQRLREKMWHGRQRLGGVGAGSRPPMPAH 768
Query: 964 NTKA 967
T A
Sbjct: 769 PTPA 772
>gi|94536803 transmembrane protein 16K [Homo sapiens]
Length = 660
Score = 129 bits (323), Expect = 2e-29
Identities = 124/543 (22%), Positives = 228/543 (41%), Gaps = 131/543 (24%)
Query: 271 LLANGVYAAAYPLHDGDYNGENVEFNDRKLLYEEW-ARYGVFYKYQPIDLVRKYFGEKIG 329
LL +G+ +PLHD + K L + W R+ + KYQPID +R YFGE I
Sbjct: 161 LLTSGIVIQVFPLHDSEA---------LKKLEDTWYTRFAL--KYQPIDSIRGYFGETIA 209
Query: 330 LYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYW 389
LYF +L +T LIP +++G+ +L+ W
Sbjct: 210 LYFGFLEYFTFALIPMAVIGLPYYLF--------------------------------VW 237
Query: 390 KMSSACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEA 449
+ D V F+ F +W+ +E WKR + YRW + + E
Sbjct: 238 E--------------DYDKYVIFASFNLIWSTVILELWKRGCANMTYRWGTLLMKRKFE- 282
Query: 450 VKDHPRAEYEARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTW 509
PR + + S+ KE+ P + K + R+
Sbjct: 283 ---EPRPGFHGVLGINSIT----GKEE----PLYPSYKRQLRIY---------------- 315
Query: 510 RDRFPAYLTNLVSIIFM-IAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATA 568
LVS+ F+ + + F++ + +I + + + A +S S +++ + V +
Sbjct: 316 ----------LVSLPFVCLCLYFSLYVMMIYFDMEVWALGLHENSGSEWTSVLLYVPS-- 363
Query: 569 VIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFF 628
II +VI +++ +Y A +LT E + E +++ LI K + F+N + +FY+AF
Sbjct: 364 -IIYAIVIEIMNRLYRYAAEFLTSWENHRLESAYQNHLILKVLVFNFLNCFASLFYIAF- 421
Query: 629 KGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIP---K 685
+ + ++ L L+ +++ Q++ N + E +P +
Sbjct: 422 -------------VLKDMKL-----------LRQSLATLLITSQIL-NQIMESFLPYWLQ 456
Query: 686 MKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVAS 745
K +R + Q D + + + E + + + G +Y+E+ +QFG+V+LF
Sbjct: 457 RKHGVRVKRKVQALKADIDATLYEQVILEKE--MGTYLGTFDDYLELFLQFGYVSLFSCV 514
Query: 746 FPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVI 805
+PLA FA+LNN E+ DA K +RP + + +IG+W + ++V+ N +I
Sbjct: 515 YPLAAAFAVLNNFTEVNSDALKMCRVFKRPFSEPSANIGVWQLAFETMSVISVVTNCALI 574
Query: 806 SFT 808
+
Sbjct: 575 GMS 577
>gi|55741655 anoctamin 8 [Homo sapiens]
Length = 1232
Score = 89.0 bits (219), Expect = 2e-17
Identities = 43/106 (40%), Positives = 67/106 (63%), Gaps = 1/106 (0%)
Query: 700 PPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNII 759
PP+ E + Q E++ ++ + +Y EM +QFG+V LF ++FPLA L AL+NN+I
Sbjct: 720 PPEEEHSPQLTQA-ELESCMKKYEDTFQDYQEMFVQFGYVVLFSSAFPLAALCALVNNLI 778
Query: 760 EIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVI 805
EIR DA K T L+RP R + IG W ++ +G LA+++N ++I
Sbjct: 779 EIRSDAFKLCTGLQRPFGQRVESIGQWQKVMEAMGVLAIVVNCYLI 824
Score = 87.0 bits (214), Expect = 8e-17
Identities = 88/415 (21%), Positives = 158/415 (38%), Gaps = 107/415 (25%)
Query: 224 FSREKQHLFDLSDKD-SFFDSKTRSTIVYEILKRTTCTKAKYSMG---------ITSLLA 273
FS E+ +++ + + FF S+ R +I+ L+ + + I L A
Sbjct: 142 FSCEEDFIYENVESELRFFTSQERQSIIRFWLQNLRAKQGEALHNVRFLEDQPIIPELAA 201
Query: 274 NGVYAAAYPLHDGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFA 333
G+ +P+H E L + W + + QP+D + YFG KI +YFA
Sbjct: 202 RGIIQQVFPVH---------EQRILNRLMKSWVQ--AVCENQPLDDICDYFGVKIAMYFA 250
Query: 334 WLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSS 393
WLG YT ++ ++ G +++ + A DQ C
Sbjct: 251 WLGFYTSAMVYPAVFGSVLYTFTEA------------DQTSRDVSC-------------- 284
Query: 394 ACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDH 453
V F++F +W+ F+E WKR+ L Y+W + EAV++
Sbjct: 285 ----------------VVFALFNVIWSTLFLEEWKRRGAELAYKWGT--LDSPGEAVEE- 325
Query: 454 PRAEYEARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRF 513
PR ++ GV+ + +
Sbjct: 326 PRPQFR--------------------------------------GVRRISPITRAEEFYY 347
Query: 514 PAYLTNLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINL 573
P + L ++ + + A + V ++ + + SV+ R+ V++ L
Sbjct: 348 PPWKRLLFQLLVSLPLCLACL--VCVFLLMLGCFQLQELVLSVKGLPRLARFLPKVMLAL 405
Query: 574 VVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFF 628
+V + E Y +A WL +E + E ++E+ LI K L +FVNSY +FY+ F+
Sbjct: 406 LVSVSA-EGYKKLAIWLNDMENYRLESAYEKHLIIKVVLFQFVNSYLSLFYIGFY 459
Score = 36.6 bits (83), Expect = 0.12
Identities = 17/74 (22%), Positives = 36/74 (48%)
Query: 884 WAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQ 943
W A + V+V ++ + + + IPDIP +++++ K + E F R E+ Q
Sbjct: 836 WLSPEAAIVSVVVLEHFALLLKYLIHVAIPDIPGWVAEEMAKLEYQRREAFKRHERQAQH 895
Query: 944 LLETWMEKERQKDE 957
+ + R+++E
Sbjct: 896 RYQQQQRRRREEEE 909
>gi|239741065 PREDICTED: hypothetical protein [Homo sapiens]
Length = 494
Score = 79.0 bits (193), Expect = 2e-14
Identities = 77/270 (28%), Positives = 116/270 (42%), Gaps = 66/270 (24%)
Query: 649 EECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVK 708
++C PGGC +++ QL IIM+GKQL+ + +G+ P C+
Sbjct: 231 QQCGPGGCHIQVTQQLIIIMVGKQLLNHMEEFVGLGG-------------GPGPDTPCL- 276
Query: 709 RKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKF 768
PE +QFGF+T+FV +F LAPLF LLNN +EI LDA KF
Sbjct: 277 ------------------PE-----LQFGFITIFVGAFLLAPLFTLLNNRVEIGLDAHKF 313
Query: 769 VTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMH 828
+ + +RP+A R G + R + NA R Y + G +
Sbjct: 314 LCKYQRPMAGRGWTSGSDCSCWRPCELILPRTNA-----------RSRLGYWLNGQGQIL 362
Query: 829 GFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLA 888
G + F G +PL + RYK R+ +++ +W +LA
Sbjct: 363 GRRRGGNAGF-------GVEIREPL----QTPQPRYKASRDV-----GVNLALFYWKLLA 406
Query: 889 --ARLAFVIVFQNLVMFMSDFVDWVIPDIP 916
L F+I F+N+V F D ++PD+P
Sbjct: 407 VHVHLGFIIAFENVVFFFLCPNDRLVPDVP 436
Score = 44.3 bits (103), Expect = 6e-04
Identities = 38/175 (21%), Positives = 73/175 (41%), Gaps = 25/175 (14%)
Query: 399 RASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEY 458
+ S LFD+P TVFFS+FM+ W + L + WD + F+++E P
Sbjct: 50 KLSCLFDHPGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQDQEAMPSSAPH--- 106
Query: 459 EARVLEKSLKKESRNKEKRRHIPEESTNKWK----QRVKTAMAGVKLTDKVKLTWRDRF- 513
+ + + + +P + + W Q + A +++T ++ +
Sbjct: 107 ---------HWDCSDFQDQEVMPSSALHHWDCSDFQDQEFAALALQMTQNPVTGLKEPYF 157
Query: 514 ------PAYLTNLVSIIFMIAVTFAIVLGVIIYR--ISMAAALAMNSSPSVRSNI 560
LT+ +I+ ++ V ++ VIIY IS+A NS ++N+
Sbjct: 158 QPHSCLSHLLTSSAAILTVLCVVMIFLVSVIIYHGIISIAMFHTGNSVLMTQANV 212
Score = 32.7 bits (73), Expect = 1.7
Identities = 13/31 (41%), Positives = 19/31 (61%)
Query: 288 YNGENVEFNDRKLLYEEWARYGVFYKYQPID 318
Y + N +LLY WA +G ++KYQP+D
Sbjct: 15 YQVPGSDLNSCQLLYPYWACWGYWHKYQPLD 45
>gi|169161033 PREDICTED: hypothetical protein [Homo sapiens]
Length = 723
Score = 78.2 bits (191), Expect = 4e-14
Identities = 77/269 (28%), Positives = 115/269 (42%), Gaps = 66/269 (24%)
Query: 650 ECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKR 709
+C PGGC +++ QL IIM+GKQL+ + +G+ P C+
Sbjct: 461 QCGPGGCHIQVTQQLIIIMVGKQLLNHMEEFVGLGG-------------GPGPDTPCL-- 505
Query: 710 KQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFV 769
PE +QFGF+T+FV +F LAPLF LLNN +EI LDA KF+
Sbjct: 506 -----------------PE-----LQFGFITIFVGAFLLAPLFTLLNNRVEIGLDAHKFL 543
Query: 770 TELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHG 829
+ +RP+A R G + R + NA R Y + G + G
Sbjct: 544 CKYQRPMAGRGWTSGSDCSCWRPCELILPRTNA-----------RSRLGYWLNGQGQILG 592
Query: 830 FVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLA- 888
+ F G +PL + RYK R+ +++ +W +LA
Sbjct: 593 RRRGGNAGF-------GVEIREPL----QTPQPRYKASRDV-----GVNLALFYWKLLAV 636
Query: 889 -ARLAFVIVFQNLVMFMSDFVDWVIPDIP 916
L F+I F+N+V F D ++PD+P
Sbjct: 637 HVHLGFIIAFENVVFFFLCPNDRLVPDVP 665
Score = 34.3 bits (77), Expect = 0.59
Identities = 16/52 (30%), Positives = 24/52 (46%)
Query: 403 LFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHP 454
L D TVFFS+FM+ W + L + WD + F+++E P
Sbjct: 262 LGDGLGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQDQEAMPSSAP 313
>gi|239747244 PREDICTED: hypothetical protein [Homo sapiens]
Length = 719
Score = 78.2 bits (191), Expect = 4e-14
Identities = 77/269 (28%), Positives = 115/269 (42%), Gaps = 66/269 (24%)
Query: 650 ECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKR 709
+C PGGC +++ QL IIM+GKQL+ + +G+ P C+
Sbjct: 457 QCGPGGCHIQVTQQLIIIMVGKQLLNHMEEFVGLGG-------------GPGPDTPCL-- 501
Query: 710 KQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFV 769
PE +QFGF+T+FV +F LAPLF LLNN +EI LDA KF+
Sbjct: 502 -----------------PE-----LQFGFITIFVGAFLLAPLFTLLNNRVEIGLDAHKFL 539
Query: 770 TELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHG 829
+ +RP+A R G + R + NA R Y + G + G
Sbjct: 540 CKYQRPMAGRGWTSGSDCSCWRPCELILPRTNA-----------RSRLGYWLNGQGQILG 588
Query: 830 FVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLA- 888
+ F G +PL + RYK R+ +++ +W +LA
Sbjct: 589 RRRGGNAGF-------GVEIREPL----QTPQPRYKASRDV-----GVNLALFYWKLLAV 632
Query: 889 -ARLAFVIVFQNLVMFMSDFVDWVIPDIP 916
L F+I F+N+V F D ++PD+P
Sbjct: 633 HVHLGFIIAFENVVFFFLCPNDRLVPDVP 661
Score = 42.7 bits (99), Expect = 0.002
Identities = 19/56 (33%), Positives = 29/56 (51%)
Query: 399 RASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHP 454
+ S LFD+P TVFFS+FM+ W + L + WD + F+++E P
Sbjct: 254 KLSCLFDHPGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQDQEAMPSSAP 309
Score = 40.0 bits (92), Expect = 0.011
Identities = 27/70 (38%), Positives = 37/70 (52%), Gaps = 9/70 (12%)
Query: 250 VYEILKRTTCTKAKYS-MGITSLLANGVYAAAYPLHDGDYNGENVEFNDRKLLYEEWARY 308
V EIL RT K K++ MGI LL G++ Y + N +LLY WA +
Sbjct: 188 VAEILDRTISRKKKHTEMGIAHLL--GLFELP------GYQVPGSDLNSCQLLYPYWACW 239
Query: 309 GVFYKYQPID 318
G ++KYQP+D
Sbjct: 240 GYWHKYQPLD 249
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 33.9 bits (76), Expect = 0.77
Identities = 19/50 (38%), Positives = 26/50 (52%)
Query: 444 EEEEEAVKDHPRAEYEARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVK 493
EEEEE ++ R E E R E+ K+E +EK+ EE K K+ K
Sbjct: 2246 EEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKK 2295
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 33.9 bits (76), Expect = 0.77
Identities = 24/70 (34%), Positives = 32/70 (45%), Gaps = 7/70 (10%)
Query: 425 EHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKEKRRHIPEES 484
E KRK+ R + EEEE ++ E E EK + + K+KRR EE
Sbjct: 58 EEKKRKRKRKKKK-------EEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEE 110
Query: 485 TNKWKQRVKT 494
K K+R KT
Sbjct: 111 EKKKKRRRKT 120
Score = 31.2 bits (69), Expect = 5.0
Identities = 20/66 (30%), Positives = 32/66 (48%), Gaps = 3/66 (4%)
Query: 428 KRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKEKRRHIPEESTNK 487
K+K+ + T EEE+E + R E EK KK+++ EKR+ EE +
Sbjct: 6 KKKETEETEETEETEEEEEKEGKRKEKRKEKRK---EKEKKKKTKETEKRKEKEEEEKKR 62
Query: 488 WKQRVK 493
++R K
Sbjct: 63 KRKRKK 68
>gi|31542760 hypothetical protein LOC220108 [Homo sapiens]
Length = 582
Score = 33.1 bits (74), Expect = 1.3
Identities = 22/80 (27%), Positives = 40/80 (50%), Gaps = 15/80 (18%)
Query: 898 QNLVMFMSDFVDWVIPDIP------KDISQQIHK-----EKVLMVELFMREEQDKQQLLE 946
Q L + + + W+ PD+P + S++ K + L V LF++EE ++Q+L+
Sbjct: 95 QPLQEAIDNVLAWIHPDLPLFRVSERRASRRRRKPPKGAQPALAVVLFLQEEYGEEQILQ 154
Query: 947 TWMEKERQKDEPPCNHHNTK 966
R +PP HH+T+
Sbjct: 155 L----HRTLQQPPWRHHHTE 170
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 32.3 bits (72), Expect = 2.2
Identities = 21/91 (23%), Positives = 40/91 (43%), Gaps = 11/91 (12%)
Query: 431 QMRLNYRWDLTGFEEEEEAVKDHPRA-EYEARVLEKSLK----------KESRNKEKRRH 479
Q+ N W+L ++EE+ + + E E ++ E+ LK +E + E+
Sbjct: 281 QVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEK 340
Query: 480 IPEESTNKWKQRVKTAMAGVKLTDKVKLTWR 510
I E+ W+Q K K+ ++ + WR
Sbjct: 341 IREQEDKMWRQEEKIREQEEKIREQEEKMWR 371
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 32.3 bits (72), Expect = 2.2
Identities = 21/91 (23%), Positives = 40/91 (43%), Gaps = 11/91 (12%)
Query: 431 QMRLNYRWDLTGFEEEEEAVKDHPRA-EYEARVLEKSLK----------KESRNKEKRRH 479
Q+ N W+L ++EE+ + + E E ++ E+ LK +E + E+
Sbjct: 281 QVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEK 340
Query: 480 IPEESTNKWKQRVKTAMAGVKLTDKVKLTWR 510
I E+ W+Q K K+ ++ + WR
Sbjct: 341 IREQEDKMWRQEEKIREQEEKIREQEEKMWR 371
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 32.3 bits (72), Expect = 2.2
Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 1/67 (1%)
Query: 428 KRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKEKR-RHIPEESTN 486
+R Q RL + L EE+E +K+ + E +K +KE + KE+R + +E
Sbjct: 338 QRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEK 397
Query: 487 KWKQRVK 493
KQR+K
Sbjct: 398 AEKQRLK 404
>gi|222831595 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 [Homo sapiens]
Length = 1712
Score = 32.0 bits (71), Expect = 2.9
Identities = 15/45 (33%), Positives = 28/45 (62%)
Query: 443 FEEEEEAVKDHPRAEYEARVLEKSLKKESRNKEKRRHIPEESTNK 487
F ++++ K P+A+ EA V+ L+K ++ EK++ I E+S K
Sbjct: 1149 FLKKKQETKRPPKADKEAHVMANKLRKVKKSIEKQKIIDEKSQKK 1193
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 30.8 bits (68), Expect = 6.5
Identities = 17/70 (24%), Positives = 35/70 (50%), Gaps = 8/70 (11%)
Query: 425 EHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKEKRRHIPEES 484
E +R+Q +L E++E + + E E LE+ LK+E + + + + EE
Sbjct: 638 EQEERRQQQLR--------REQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEE 689
Query: 485 TNKWKQRVKT 494
+ ++R+K+
Sbjct: 690 QEQARERIKS 699
>gi|8923243 palmdelphin [Homo sapiens]
Length = 551
Score = 30.8 bits (68), Expect = 6.5
Identities = 19/59 (32%), Positives = 35/59 (59%), Gaps = 6/59 (10%)
Query: 424 MEHWKRKQMRLNYRWDLTGF---EEEEEAVKDHPRAEYEARVLEKS---LKKESRNKEK 476
++H K+ L +W L G +E+EE K + + +++ +VLE+S L+KE ++ EK
Sbjct: 36 LKHQHLKKKALREKWLLDGISSGKEQEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEK 94
>gi|32129212 zinc finger protein 434 [Homo sapiens]
Length = 485
Score = 30.8 bits (68), Expect = 6.5
Identities = 20/78 (25%), Positives = 36/78 (46%)
Query: 427 WKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKEKRRHIPEESTN 486
+K + + N +WD + E +A++ R Y L+K L+ E ++ + R+ P ES
Sbjct: 203 FKNEIKKENLKWDDSEEVEINKALQRKSRGVYWHSELQKGLESEPTSRRQCRNSPGESEE 262
Query: 487 KWKQRVKTAMAGVKLTDK 504
K + K + DK
Sbjct: 263 KTPSQEKMSHQSFCARDK 280
>gi|237858799 adenylate kinase domain containing 1 isoform 1 [Homo
sapiens]
Length = 1911
Score = 30.4 bits (67), Expect = 8.5
Identities = 15/44 (34%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 438 WDLTGFEEEEEAVKDHPRAEYEARVLEKSLKK-ESRNKEKRRHI 480
W+LTG + EEE AE + + E+ ++ E + KE++RH+
Sbjct: 886 WELTGEDYEEETEDYQTEAEVDEELEEEEEEEGEDKMKERKRHL 929
>gi|11225260 DNA topoisomerase I [Homo sapiens]
Length = 765
Score = 30.4 bits (67), Expect = 8.5
Identities = 15/37 (40%), Positives = 20/37 (54%)
Query: 454 PRAEYEARVLEKSLKKESRNKEKRRHIPEESTNKWKQ 490
PR E +A K +K E KEK+R + EE K K+
Sbjct: 139 PRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKK 175
>gi|145386566 zinc finger protein 148 [Homo sapiens]
Length = 794
Score = 30.4 bits (67), Expect = 8.5
Identities = 20/68 (29%), Positives = 33/68 (48%), Gaps = 1/68 (1%)
Query: 183 HINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLS-YPFSREKQHLFDLSDKDSFF 241
H+ + G + VL+KI K + QT+ LS Y S+ ++ F+L DK +
Sbjct: 377 HLEDASGEIHPPKLVLKKINSKRSLKQPLEQNQTISPLSTYEESKVSKYAFELVDKQALL 436
Query: 242 DSKTRSTI 249
DS+ + I
Sbjct: 437 DSEGNADI 444
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.138 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,635,918
Number of Sequences: 37866
Number of extensions: 1718107
Number of successful extensions: 5495
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 5241
Number of HSP's gapped (non-prelim): 153
length of query: 986
length of database: 18,247,518
effective HSP length: 112
effective length of query: 874
effective length of database: 14,006,526
effective search space: 12241703724
effective search space used: 12241703724
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.