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Search of human proteins with 113416996
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|113416996 PREDICTED: ankyrin repeat domain 33B [Homo
sapiens]
(1006 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|113416996 PREDICTED: ankyrin repeat domain 33B [Homo sapiens] 2075 0.0
gi|169167742 PREDICTED: ankyrin repeat domain 33B [Homo sapiens] 924 0.0
gi|239742483 PREDICTED: ankyrin repeat domain 33B [Homo sapiens] 924 0.0
gi|194097375 ankyrin repeat domain 33 isoform 2 [Homo sapiens] 231 3e-60
gi|194097377 ankyrin repeat domain 33 isoform 1 [Homo sapiens] 213 7e-55
gi|62988328 ankyrin repeat domain 50 [Homo sapiens] 75 3e-13
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 74 9e-13
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 72 2e-12
gi|24308163 fem-1 homolog a [Homo sapiens] 71 4e-12
gi|96975023 ankyrin repeat and death domain containing 1A [Homo ... 71 6e-12
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 68 4e-11
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 67 6e-11
gi|160707881 formin 2 [Homo sapiens] 67 1e-10
gi|169208819 PREDICTED: similar to kinase D-interacting substrat... 66 1e-10
gi|169208593 PREDICTED: similar to kinase D-interacting substrat... 66 1e-10
gi|55741641 kinase D-interacting substrate of 220 kDa [Homo sapi... 66 1e-10
gi|46519154 ankyrin repeat and KH domain containing 1 isoform 3 ... 65 2e-10
gi|46519151 ankyrin repeat and KH domain containing 1 isoform 2 ... 65 2e-10
gi|46519147 ankyrin repeat and KH domain containing 1 isoform 1 ... 65 2e-10
gi|37620163 ANKHD1-EIF4EBP3 protein [Homo sapiens] 65 2e-10
gi|70995267 ankyrin repeat domain 29 [Homo sapiens] 65 2e-10
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 65 4e-10
gi|239744358 PREDICTED: hypothetical protein XP_002343105 [Homo ... 64 7e-10
gi|169208169 PREDICTED: similar to kinase D-interacting substrat... 64 9e-10
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] 63 1e-09
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens] 63 1e-09
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens] 63 1e-09
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens] 63 1e-09
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens] 63 1e-09
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens] 63 1e-09
>gi|113416996 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]
Length = 1006
Score = 2075 bits (5377), Expect = 0.0
Identities = 1006/1006 (100%), Positives = 1006/1006 (100%)
Query: 1 MSTNRLREARKGCVVLPSQGLALSTWALVTRSRDSCCKVTQCSPWEDKRIPGVEKEASES 60
MSTNRLREARKGCVVLPSQGLALSTWALVTRSRDSCCKVTQCSPWEDKRIPGVEKEASES
Sbjct: 1 MSTNRLREARKGCVVLPSQGLALSTWALVTRSRDSCCKVTQCSPWEDKRIPGVEKEASES 60
Query: 61 QFAARSEPPRCEGVFTRNRCSRAPHPPGPCRCRVGGRQQALWLLLETLEDQATRTAGRAS 120
QFAARSEPPRCEGVFTRNRCSRAPHPPGPCRCRVGGRQQALWLLLETLEDQATRTAGRAS
Sbjct: 61 QFAARSEPPRCEGVFTRNRCSRAPHPPGPCRCRVGGRQQALWLLLETLEDQATRTAGRAS 120
Query: 121 ALAQRHVGLKPGPQRLRQPSCVHLGAARASHRLAAGGHAVKIGGKKGRKEARGTQGWWPP 180
ALAQRHVGLKPGPQRLRQPSCVHLGAARASHRLAAGGHAVKIGGKKGRKEARGTQGWWPP
Sbjct: 121 ALAQRHVGLKPGPQRLRQPSCVHLGAARASHRLAAGGHAVKIGGKKGRKEARGTQGWWPP 180
Query: 181 QSLTCDGRERTSAPLRRDLPPRLAHDASYPEVKGSLWQILTRPPPPRPSPAPGLTGRGQG 240
QSLTCDGRERTSAPLRRDLPPRLAHDASYPEVKGSLWQILTRPPPPRPSPAPGLTGRGQG
Sbjct: 181 QSLTCDGRERTSAPLRRDLPPRLAHDASYPEVKGSLWQILTRPPPPRPSPAPGLTGRGQG 240
Query: 241 RARGAVGLDCGCRPRPCSFGQPDVGSAPSRSLRGCSLRFRNTPPPIPGSDQPSSHGRPRF 300
RARGAVGLDCGCRPRPCSFGQPDVGSAPSRSLRGCSLRFRNTPPPIPGSDQPSSHGRPRF
Sbjct: 241 RARGAVGLDCGCRPRPCSFGQPDVGSAPSRSLRGCSLRFRNTPPPIPGSDQPSSHGRPRF 300
Query: 301 RETGDSEDCPPFRAGTPPQQPTAPSSEWPGPQRSPGTGPRWTAPLPRPAPLPAKRPGDSP 360
RETGDSEDCPPFRAGTPPQQPTAPSSEWPGPQRSPGTGPRWTAPLPRPAPLPAKRPGDSP
Sbjct: 301 RETGDSEDCPPFRAGTPPQQPTAPSSEWPGPQRSPGTGPRWTAPLPRPAPLPAKRPGDSP 360
Query: 361 ASKRPRPGGVSPEARDPPKGENPLCSSEAAGETGPTQVRGPDALGGGRLQGKGREGKAPG 420
ASKRPRPGGVSPEARDPPKGENPLCSSEAAGETGPTQVRGPDALGGGRLQGKGREGKAPG
Sbjct: 361 ASKRPRPGGVSPEARDPPKGENPLCSSEAAGETGPTQVRGPDALGGGRLQGKGREGKAPG 420
Query: 421 EGVSPRPAPPRLGKPPRSRPPQGLAQPPETFFFERSRLVPVSAELERAGHGFSGDAEARS 480
EGVSPRPAPPRLGKPPRSRPPQGLAQPPETFFFERSRLVPVSAELERAGHGFSGDAEARS
Sbjct: 421 EGVSPRPAPPRLGKPPRSRPPQGLAQPPETFFFERSRLVPVSAELERAGHGFSGDAEARS 480
Query: 481 GDLGARPASRSSLPSAPAPPAQQPQAARHGAAGRDQGRRAAGAQLHDPTTQPSPPTGAQQ 540
GDLGARPASRSSLPSAPAPPAQQPQAARHGAAGRDQGRRAAGAQLHDPTTQPSPPTGAQQ
Sbjct: 481 GDLGARPASRSSLPSAPAPPAQQPQAARHGAAGRDQGRRAAGAQLHDPTTQPSPPTGAQQ 540
Query: 541 VEEDPADYEEFEDILESARHPQASHSDDSFYPFEDEEEHGVESAESVPEGVPESVPETAT 600
VEEDPADYEEFEDILESARHPQASHSDDSFYPFEDEEEHGVESAESVPEGVPESVPETAT
Sbjct: 541 VEEDPADYEEFEDILESARHPQASHSDDSFYPFEDEEEHGVESAESVPEGVPESVPETAT 600
Query: 601 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 660
LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV
Sbjct: 601 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 660
Query: 661 NWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRA 720
NWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRA
Sbjct: 661 NWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRA 720
Query: 721 LMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPE 780
LMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPE
Sbjct: 721 LMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPE 780
Query: 781 AARKPAGSKNCLQRLTDCVLSVLTPRSVRGPEDGGVLDHMVRMTTSLYSPAVAIVCQTVC 840
AARKPAGSKNCLQRLTDCVLSVLTPRSVRGPEDGGVLDHMVRMTTSLYSPAVAIVCQTVC
Sbjct: 781 AARKPAGSKNCLQRLTDCVLSVLTPRSVRGPEDGGVLDHMVRMTTSLYSPAVAIVCQTVC 840
Query: 841 PESPPSVGKRRLAVQEILAARAARGPQAQEEDEVGGAGQRGRTGQEDADSREGSPRAGLP 900
PESPPSVGKRRLAVQEILAARAARGPQAQEEDEVGGAGQRGRTGQEDADSREGSPRAGLP
Sbjct: 841 PESPPSVGKRRLAVQEILAARAARGPQAQEEDEVGGAGQRGRTGQEDADSREGSPRAGLP 900
Query: 901 PALGSRGPAAPAPRKASLLPLQRLRRRSVRPGVVVPRVRVSKAPAPTFQPERPARKGSTK 960
PALGSRGPAAPAPRKASLLPLQRLRRRSVRPGVVVPRVRVSKAPAPTFQPERPARKGSTK
Sbjct: 901 PALGSRGPAAPAPRKASLLPLQRLRRRSVRPGVVVPRVRVSKAPAPTFQPERPARKGSTK 960
Query: 961 DSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAEAQKERRTAPWKKRT 1006
DSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAEAQKERRTAPWKKRT
Sbjct: 961 DSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAEAQKERRTAPWKKRT 1006
>gi|169167742 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]
Length = 494
Score = 924 bits (2389), Expect = 0.0
Identities = 466/490 (95%), Positives = 469/490 (95%), Gaps = 3/490 (0%)
Query: 517 GRRAAGAQLHDPTTQPSPPTGAQQVEEDPADYEEFEDILESARHPQASHSDDSFYPFEDE 576
G GA+ P PSPP GAQ VEEDPADYEEFED S ++ SDDSFYPFEDE
Sbjct: 8 GPEGGGARCMTPPP-PSPPRGAQ-VEEDPADYEEFEDF-SSLPDTRSIASDDSFYPFEDE 64
Query: 577 EEHGVESAESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTG 636
EEHGVESAESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTG
Sbjct: 65 EEHGVESAESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTG 124
Query: 637 LIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE 696
LIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE
Sbjct: 125 LIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE 184
Query: 697 RRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQ 756
RRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQ
Sbjct: 185 RRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQ 244
Query: 757 RLLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPEDGGV 816
RLLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPEDGGV
Sbjct: 245 RLLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPEDGGV 304
Query: 817 LDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARGPQAQEEDEVGG 876
LDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARGPQAQEEDEVGG
Sbjct: 305 LDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARGPQAQEEDEVGG 364
Query: 877 AGQRGRTGQEDADSREGSPRAGLPPALGSRGPAAPAPRKASLLPLQRLRRRSVRPGVVVP 936
AGQRGRTGQEDADSREGSPRAGLPPALGSRGPAAPAPRKASLLPLQRLRRRSVRPGVVVP
Sbjct: 365 AGQRGRTGQEDADSREGSPRAGLPPALGSRGPAAPAPRKASLLPLQRLRRRSVRPGVVVP 424
Query: 937 RVRVSKAPAPTFQPERPARKGSTKDSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAEAQKE 996
RVRVSKAPAPTFQPERPARKGSTKDSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAEAQKE
Sbjct: 425 RVRVSKAPAPTFQPERPARKGSTKDSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAEAQKE 484
Query: 997 RRTAPWKKRT 1006
RRTAPWKKRT
Sbjct: 485 RRTAPWKKRT 494
Score = 33.5 bits (75), Expect = 1.0
Identities = 41/150 (27%), Positives = 56/150 (37%), Gaps = 27/150 (18%)
Query: 370 VSPEARDPPKGENPLCSSEAAGETGPTQVRGPDALGGGRLQGKGREGKAPGEGVSPRPAP 429
V PE+ P G+ L E RGP A + G G+ G+ E R
Sbjct: 327 VCPES-PPSVGKRRLAVQEILAARA---ARGPQAQEEDEVGGAGQRGRTGQEDADSREGS 382
Query: 430 PRLGKPPR--SRPPQGLAQPPETFFFERSRLVPVSAELERAGHGFSGDAEARSGDLGARP 487
PR G PP SR P A ++ L+P+ R+ R G +
Sbjct: 383 PRAGLPPALGSRGPAAPAP-------RKASLLPLQRLRRRS---------VRPGVV---- 422
Query: 488 ASRSSLPSAPAPPAQQPQAARHGAAGRDQG 517
R + APAP Q + AR G+ +D G
Sbjct: 423 VPRVRVSKAPAPTFQPERPARKGST-KDSG 451
>gi|239742483 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]
Length = 494
Score = 924 bits (2389), Expect = 0.0
Identities = 466/490 (95%), Positives = 469/490 (95%), Gaps = 3/490 (0%)
Query: 517 GRRAAGAQLHDPTTQPSPPTGAQQVEEDPADYEEFEDILESARHPQASHSDDSFYPFEDE 576
G GA+ P PSPP GAQ VEEDPADYEEFED S ++ SDDSFYPFEDE
Sbjct: 8 GPEGGGARCMTPPP-PSPPRGAQ-VEEDPADYEEFEDF-SSLPDTRSIASDDSFYPFEDE 64
Query: 577 EEHGVESAESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTG 636
EEHGVESAESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTG
Sbjct: 65 EEHGVESAESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTG 124
Query: 637 LIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE 696
LIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE
Sbjct: 125 LIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE 184
Query: 697 RRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQ 756
RRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQ
Sbjct: 185 RRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQ 244
Query: 757 RLLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPEDGGV 816
RLLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPEDGGV
Sbjct: 245 RLLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPEDGGV 304
Query: 817 LDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARGPQAQEEDEVGG 876
LDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARGPQAQEEDEVGG
Sbjct: 305 LDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARGPQAQEEDEVGG 364
Query: 877 AGQRGRTGQEDADSREGSPRAGLPPALGSRGPAAPAPRKASLLPLQRLRRRSVRPGVVVP 936
AGQRGRTGQEDADSREGSPRAGLPPALGSRGPAAPAPRKASLLPLQRLRRRSVRPGVVVP
Sbjct: 365 AGQRGRTGQEDADSREGSPRAGLPPALGSRGPAAPAPRKASLLPLQRLRRRSVRPGVVVP 424
Query: 937 RVRVSKAPAPTFQPERPARKGSTKDSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAEAQKE 996
RVRVSKAPAPTFQPERPARKGSTKDSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAEAQKE
Sbjct: 425 RVRVSKAPAPTFQPERPARKGSTKDSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAEAQKE 484
Query: 997 RRTAPWKKRT 1006
RRTAPWKKRT
Sbjct: 485 RRTAPWKKRT 494
Score = 33.5 bits (75), Expect = 1.0
Identities = 41/150 (27%), Positives = 56/150 (37%), Gaps = 27/150 (18%)
Query: 370 VSPEARDPPKGENPLCSSEAAGETGPTQVRGPDALGGGRLQGKGREGKAPGEGVSPRPAP 429
V PE+ P G+ L E RGP A + G G+ G+ E R
Sbjct: 327 VCPES-PPSVGKRRLAVQEILAARA---ARGPQAQEEDEVGGAGQRGRTGQEDADSREGS 382
Query: 430 PRLGKPPR--SRPPQGLAQPPETFFFERSRLVPVSAELERAGHGFSGDAEARSGDLGARP 487
PR G PP SR P A ++ L+P+ R+ R G +
Sbjct: 383 PRAGLPPALGSRGPAAPAP-------RKASLLPLQRLRRRS---------VRPGVV---- 422
Query: 488 ASRSSLPSAPAPPAQQPQAARHGAAGRDQG 517
R + APAP Q + AR G+ +D G
Sbjct: 423 VPRVRVSKAPAPTFQPERPARKGST-KDSG 451
>gi|194097375 ankyrin repeat domain 33 isoform 2 [Homo sapiens]
Length = 452
Score = 231 bits (588), Expect = 3e-60
Identities = 165/451 (36%), Positives = 223/451 (49%), Gaps = 54/451 (11%)
Query: 554 ILESARHPQAS---HSDDSFYPFEDEEEHGVESAE-SVPEGVPESVPETAT-------LL 602
++++ R P AS P +EEE + + E +P ET T L
Sbjct: 41 LIDTLRTPNASCMRKGTHLLVPCLEEEELALHRRRLDMSEALPCPGKETPTPGCRLGALY 100
Query: 603 RAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNW 662
A N+ L+ ++ GVS EEA + D NGRTGL+VACYHGF V L+ CP +DVN
Sbjct: 101 WACVHNDPTQLQAILDGGVSPEEATQVDSNGRTGLMVACYHGFQSVVALLSHCPFLDVNQ 160
Query: 663 QDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALM 722
QD G+TAL+ AAQAGH + + LLNY+ GLDLERR+ G TALMKAAM+ R
Sbjct: 161 QDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRC------- 213
Query: 723 LAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAA 782
AD+ A DP RG + EWA T D V +++LL RP EQ + Y+PE P
Sbjct: 214 ---ADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQLLRRPQVEQLSQHYKPEWPALSGLV 270
Query: 783 RKPAGSKNCLQRLTDCVLSVLTPRSVRGPEDGGVLDHMVRMTTSLYSPAVAIVCQTVCPE 842
+ L + + + L+ P++GGVLDH+V TTSL SP V C T+CP+
Sbjct: 271 AQAQAQAQVAPSLLERLQATLSLPFAPSPQEGGVLDHLVTATTSLASPFVTTACHTLCPD 330
Query: 843 SPPSVGKRRLAVQEILAARAARGPQAQEEDEVGGAGQRGRTGQEDADSREGSPRAGLPPA 902
PPS+G R +V E+L G A Q S + SP +P
Sbjct: 331 HPPSLGTRSKSVPELL----------------GTAPPPPLVPQSPPGSPQRSPWVFVP-- 372
Query: 903 LGSRGPAAPAPRKASLLPLQRLRRR-SVRPGVVVPRVRVSKAPAPTFQPERPARKGSTKD 961
+P+ LQ L+ R S P VP++ +SKA + + Q +
Sbjct: 373 -------YQSPQGILSKCLQWLQPRDSTSPRPQVPKILLSKASSSSHQCQP-----KPSP 420
Query: 962 SGH--LQIPKWRYKEAKEEKRKAEEAEKKRQ 990
SGH L +P WRY+E + EKRK EE + Q
Sbjct: 421 SGHQSLALPLWRYQELRIEKRKQEEEARMAQ 451
>gi|194097377 ankyrin repeat domain 33 isoform 1 [Homo sapiens]
Length = 272
Score = 213 bits (542), Expect = 7e-55
Identities = 117/271 (43%), Positives = 156/271 (57%), Gaps = 14/271 (5%)
Query: 638 IVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLER 697
+VACYHGF V L+ CP +DVN QD G+TAL+ AAQAGH + + LLNY+ GLDLER
Sbjct: 1 MVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLER 60
Query: 698 RNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQR 757
R+ G TALMKAAM+ R +C+ L++AGAD+ A DP RG + EWA T D V +++
Sbjct: 61 RDQRGLTALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQ 120
Query: 758 LLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPEDGGVL 817
LL RP EQ + Y+PE P + L + + + L+ P++GGVL
Sbjct: 121 LLRRPQVEQLSQHYKPEWPALSGLVAQAQAQAQVAPSLLERLQATLSLPFAPSPQEGGVL 180
Query: 818 DHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARG------------ 865
DH+V TTSL SP V C T+CP+ PPS+G R +V E+L A+
Sbjct: 181 DHLVTATTSLASPFVTTACHTLCPDHPPSLGTRSKSVPELLVPAEAQSFRTPKSGPSSLA 240
Query: 866 -PQAQE-EDEVGGAGQRGRTGQEDADSREGS 894
P AQ+ E+E GG GQ G ED + G+
Sbjct: 241 IPGAQDREEETGGGGQNGTEVGEDGIGQAGN 271
>gi|62988328 ankyrin repeat domain 50 [Homo sapiens]
Length = 1429
Score = 75.1 bits (183), Expect = 3e-13
Identities = 56/170 (32%), Positives = 82/170 (48%), Gaps = 9/170 (5%)
Query: 578 EHGVESAESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGL 637
+HG E +G + A L A + ++ L+ RG V+ D++G T L
Sbjct: 698 DHGAEVNHEDVDG--RTALSVAALCVPASKGHASVVSLLIDRGAEVDHC---DKDGMTPL 752
Query: 638 IVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLER 697
+VA Y G VD V L E DV+ D+ G T L+ AA GHA + N LL F G ++
Sbjct: 753 LVAAYEGHVDVVDLLLE-GGADVDHTDNNGRTPLLAAASMGHASVVNTLL--FWGAAVDS 809
Query: 698 RNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTG 747
++ G T L A+ QG + +R L+ G D + RD G +P A + G
Sbjct: 810 IDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDD-AGWTPLHMAAFEG 858
Score = 68.9 bits (167), Expect = 2e-11
Identities = 55/158 (34%), Positives = 79/158 (50%), Gaps = 8/158 (5%)
Query: 601 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 660
L AA + ++ L+ GV V+ A D + RT L A + G D V+ L + +V
Sbjct: 615 LRSAAWGGHTEVVSALLYAGVKVDCA---DADSRTALRAAAWGGHEDIVLNLLQ-HGAEV 670
Query: 661 NWQDSEGNTALITAAQAGHAIITNYLLNYFPGL---DLERRNAFGFTALMKAAMQGRTDC 717
N D+EG TALI AA GH I +LL++ + D++ R A AL A +G
Sbjct: 671 NKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASV 730
Query: 718 IRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 755
+ L+ GA+V D + GM+P A Y G VD V L+
Sbjct: 731 VSLLIDRGAEVDHCD-KDGMTPLLVAAYEGHVDVVDLL 767
Score = 67.0 bits (162), Expect = 8e-11
Identities = 45/120 (37%), Positives = 63/120 (52%), Gaps = 6/120 (5%)
Query: 613 LRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALI 672
+RTL+ G SV + D NGRT L A Y G +D VV L D+ +D+ G+T L
Sbjct: 528 IRTLLDNGASVNQC---DSNGRTLLANAAYSGSLD-VVNLLVSRGADLEIEDAHGHTPLT 583
Query: 673 TAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARD 732
AA+ GH + N L+ G ++ + G+TAL AA G T+ + AL+ AG V D
Sbjct: 584 LAARQGHTKVVNCLIGC--GANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCAD 641
Score = 65.5 bits (158), Expect = 2e-10
Identities = 48/158 (30%), Positives = 77/158 (48%), Gaps = 7/158 (4%)
Query: 600 TLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVD 659
TL A N + + + G +VE + D GRT L V+C+ G ++ V L H D
Sbjct: 949 TLYILALENQLTMAEYFLENGANVEAS---DAEGRTALHVSCWQGHMEMVQVLIAY-HAD 1004
Query: 660 VNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIR 719
VN D+E +AL +AA GH + L+ + G ++ G TAL AA +G D ++
Sbjct: 1005 VNAADNEKRSALQSAAWQGHVKVVQLLIEH--GAVVDHTCNQGATALCIAAQEGHIDVVQ 1062
Query: 720 ALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQR 757
L+ GAD + D + G + A G ++L+++
Sbjct: 1063 VLLEHGADPNHAD-QFGRTAMRVAAKNGHSQIIKLLEK 1099
Score = 50.4 bits (119), Expect = 8e-06
Identities = 39/124 (31%), Positives = 59/124 (47%), Gaps = 4/124 (3%)
Query: 632 NGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFP 691
+GR L VA G D +V L DVN +D++G L A + Y L
Sbjct: 912 DGRNALRVAALEGHRD-IVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLEN-- 968
Query: 692 GLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDA 751
G ++E +A G TAL + QG + ++ L+ ADV+A D + + Q A + G V
Sbjct: 969 GANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQS-AAWQGHVKV 1027
Query: 752 VRLM 755
V+L+
Sbjct: 1028 VQLL 1031
Score = 50.1 bits (118), Expect = 1e-05
Identities = 44/141 (31%), Positives = 65/141 (46%), Gaps = 9/141 (6%)
Query: 612 LLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTAL 671
+L+ LV+ G V + RT IV D++ L + VN DS G T L
Sbjct: 496 VLQLLVKAGAHVNSEDD-----RTSCIVRQALEREDSIRTLLD-NGASVNQCDSNGRTLL 549
Query: 672 ITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHAR 731
AA +G + N L++ G DLE +A G T L AA QG T + L+ GA+++
Sbjct: 550 ANAAYSGSLDVVNLLVSR--GADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHT 607
Query: 732 DPRRGMSPQEWATYTGRVDAV 752
D + G + A + G + V
Sbjct: 608 D-QDGWTALRSAAWGGHTEVV 627
Score = 42.0 bits (97), Expect = 0.003
Identities = 30/91 (32%), Positives = 42/91 (46%), Gaps = 4/91 (4%)
Query: 599 ATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHV 658
+ L AA +V +++ L+ G V+ T G T L +A G +D V L E
Sbjct: 1014 SALQSAAWQGHVKVVQLLIEHGAVVDH---TCNQGATALCIAAQEGHIDVVQVLLE-HGA 1069
Query: 659 DVNWQDSEGNTALITAAQAGHAIITNYLLNY 689
D N D G TA+ AA+ GH+ I L Y
Sbjct: 1070 DPNHADQFGRTAMRVAAKNGHSQIIKLLEKY 1100
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 73.6 bits (179), Expect = 9e-13
Identities = 75/254 (29%), Positives = 95/254 (37%), Gaps = 29/254 (11%)
Query: 223 PPPPRPSPAPGLTGRGQGRARGAVGLDCGCRPRPCSFGQPDVGSAPSRSLRGCSLRFRNT 282
PPPP P G R G G P P QP P +G + N
Sbjct: 71 PPPPGKPQGPPPQGDKSRSPRSPPGKPQG--PPPQGGNQPQGPPPPPGKPQGPPPQGGNR 128
Query: 283 P--PPIPGSDQ---PSSHGRPRFRETGDSEDCPPFRAGTPPQQPTAPSSEWPGPQRSPGT 337
P PP PG Q P R PP + G PQ P P + GP G
Sbjct: 129 PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGK 188
Query: 338 GPRWTAPLPRPAPLPAK----RPGDSPASKRPRP---GGVSPEARDPPKGEN----PLCS 386
P+ P +P P + R SP K P GG P+ PP G+ P
Sbjct: 189 KPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 248
Query: 387 SEAAGETGPTQVRGPDALGGGRLQG-KGREGKAPG----EGVSPR-PAPPRLGKP----- 435
++ G P + +GP A GG + Q + GK G EG +P+ P PP G P
Sbjct: 249 NKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQA 308
Query: 436 PRSRPPQGLAQPPE 449
P + PQG +PP+
Sbjct: 309 PPAGQPQGPPRPPQ 322
Score = 67.8 bits (164), Expect = 5e-11
Identities = 78/289 (26%), Positives = 105/289 (36%), Gaps = 52/289 (17%)
Query: 283 PPPIPGSDQPSSHGRPRFRETGDSEDCPPFRAGTPPQQPTAPSS-EWPGPQ-------RS 334
PPP PG Q PP + G PQ P P + P PQ RS
Sbjct: 50 PPPPPGKPQG-----------------PPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRS 92
Query: 335 PGTGPRWTAPL----PRPAPLPAKRPGDSPASKRPRPGGVSPEARDPPKGENPLCSSEAA 390
P P+ P P+ P P +P P RP G P + P+G P +
Sbjct: 93 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGK--PQGPPPQGDKSRS 150
Query: 391 GETGPTQVRGPDALGGGRLQGKGREGKAPGEGVSPRPAPPRLGKPPRSRPPQGLAQ--PP 448
+ P + +GP GG + QG PG+ P+ PP+ GK P+ PP G Q PP
Sbjct: 151 PRSPPGKPQGPPPQGGNQPQGPP---PPPGK---PQGPPPQGGKKPQGPPPPGKPQGPPP 204
Query: 449 ETFFFERSRLVPVSAE--LERAGHGFSGDAEARSGDLGARPASRSSLPSAPAPPAQQPQA 506
+ S+ P + + G+ G G P + P P PP +PQ
Sbjct: 205 QGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK-PQGPPPPG-KPQG 262
Query: 507 ARHGAAGRDQGRRAAGAQLHDPTTQ-------PSPPTGA--QQVEEDPA 546
+ Q R+ + P Q P PP G QQ + PA
Sbjct: 263 PPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPA 311
Score = 62.8 bits (151), Expect = 2e-09
Identities = 67/261 (25%), Positives = 90/261 (34%), Gaps = 39/261 (14%)
Query: 310 PPFRAGTPPQQPTAPSSEWPGPQRSPGTGPRWTAPLPRP-APLPAKRPGDSPASKRPRP- 367
P + G PQ P P + GP G P+ P +P P P SP S +P
Sbjct: 39 PSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQ 98
Query: 368 -----GGVSPEARDP----PKGENPLCSSEAAGETGPTQVRGPDALGG---------GRL 409
GG P+ P P+G P + G P + +GP G G+
Sbjct: 99 GPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKP 158
Query: 410 QGKGREGKAPGEGVSPRPA-----PPRLGKPPRSRPPQGLAQPPETFFFERSRLVPVSAE 464
QG +G +G P P PP+ GK P+ PP G Q P P +
Sbjct: 159 QGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGP-----------PPQGD 207
Query: 465 LERAGHGFSGDAEARSGDLGARPASRSSLPSAPAPPAQQPQAARHG--AAGRDQGRRA-A 521
R+ G + G +P P P P Q G G+ QG A
Sbjct: 208 KSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQG 267
Query: 522 GAQLHDPTTQPSPPTGAQQVE 542
G++ + P P G Q E
Sbjct: 268 GSKSQSARSPPGKPQGPPQQE 288
Score = 51.6 bits (122), Expect = 4e-06
Identities = 60/251 (23%), Positives = 81/251 (32%), Gaps = 44/251 (17%)
Query: 302 ETGDSEDCPPFRAGTPPQQPTAPSSEWPGPQRSPGTGPRWTAPLPRPAPLPAKRPGDSPA 361
E E+ P AG P GP G P+ P P P K G P
Sbjct: 21 EDVSQEESPSLIAGNPQ-----------GPSPQGGNKPQ------GPPPPPGKPQGPPPQ 63
Query: 362 SKRPRPGGVSPEARDPPKGENPLCSSEAAGETGPTQVRGPDALGGGRLQGKGREGKAPGE 421
+P G P + P+G P + + P + +GP GG + QG P
Sbjct: 64 GGN-KPQGPPPPGK--PQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQG------PPPP 114
Query: 422 GVSPRPAPPRLGKPPRSRPPQGLAQPPETFFFERSRLVPVSAELERAGHGFSGDAEARSG 481
P+ PP+ G P+ PP G Q P P + R+ G +
Sbjct: 115 PGKPQGPPPQGGNRPQGPPPPGKPQGP-----------PPQGDKSRSPRSPPGKPQGPPP 163
Query: 482 DLGARPASRSSLPSAPAPPAQQPQAARHG--AAGRDQGRRAAGAQLHDPTTQPS-----P 534
G +P P P P Q G G+ QG G + + P P
Sbjct: 164 QGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPP 223
Query: 535 PTGAQQVEEDP 545
P G Q + P
Sbjct: 224 PQGGNQPQGPP 234
Score = 41.2 bits (95), Expect = 0.005
Identities = 41/134 (30%), Positives = 52/134 (38%), Gaps = 20/134 (14%)
Query: 223 PPPPRPSPAPGLTGRGQGRARGAVGLDCGCRPRPCSFGQPDVGSAPSRSLRGCSLRFRNT 282
PPPP P G ++ G G P P QP P +G + N
Sbjct: 193 PPPPGKPQGPPPQGDKSRSSQSPPGKPQG--PPPQGGNQPQGPPPPPGKPQGPPPQGGNK 250
Query: 283 P--PPIPGSDQP-------------SSHGRPRF--RETGDSEDCPPFRAGTPPQQPTAPS 325
P PP PG Q S G+P+ ++ G++ PP AG PQQP AP
Sbjct: 251 PQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP 310
Query: 326 SEWP-GPQRSPGTG 338
+ P GP R P G
Sbjct: 311 AGQPQGPPRPPQGG 324
Score = 33.1 bits (74), Expect = 1.3
Identities = 33/130 (25%), Positives = 50/130 (38%), Gaps = 12/130 (9%)
Query: 841 PESPPSVGKRRLAVQEILAARAARGPQAQEEDEVGGAGQRGRTGQEDADSREGSPRAGLP 900
P+ PP GK + + +R+ R P + + G +G + G P+ G P
Sbjct: 68 PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQ----GPPPQGGNQPQGPPPPPGKPQ-GPP 122
Query: 901 PALGSRGPAAPAPRKASLLPLQRLRRRSVRPGVVVPR-------VRVSKAPAPTFQPERP 953
P G+R P P K P Q + RS R P+ + P P +P+ P
Sbjct: 123 PQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 182
Query: 954 ARKGSTKDSG 963
+G K G
Sbjct: 183 PPQGGKKPQG 192
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 72.4 bits (176), Expect = 2e-12
Identities = 88/342 (25%), Positives = 117/342 (34%), Gaps = 55/342 (16%)
Query: 223 PPPPRPSPAPGLTGRGQGRARGAVGLDCGCRPRPCSFGQPDVGSAPSRSLRGCSLRFRNT 282
PPPP P G R G G P P QP P +G + N
Sbjct: 92 PPPPGKPQGPPPQGDKSRSPRSPPGKPQG--PPPQGGNQPQGPPPPPGKPQGPPPQGGNK 149
Query: 283 P--PPIPGSDQ---PSSHGRPRF-RETGDSEDCPPFRAGTPPQQPTAPSSEWPGPQRSPG 336
P PP PG Q P + R R PP + G PQ P P + GP G
Sbjct: 150 PQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 209
Query: 337 TGPRWTAPLPRPAPLPAKRPGDSPASKRP--RPGGVSPEARDPPKGENPLCSSEAAGETG 394
P+ P +P P + S +++ P +P G P+ + P+G P
Sbjct: 210 NKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPP----------P 259
Query: 395 PTQVRGPDALGGGRLQGKGREGKAPGEGVSPRPAPPRLGKPPRS-RPPQGLAQPPETFFF 453
P + +GP GG + QG GK P+ PP+ G RS R P G Q P
Sbjct: 260 PGKPQGPPPQGGNKPQGPPPPGK-------PQGPPPQGGSKSRSSRSPPGKPQGPPP--- 309
Query: 454 ERSRLVPVSAELERAGHGFSGDAEARSGDLGARPASRSSLPSAPAPPAQQPQAARHGAAG 513
+ G+ G G P + P P PP +PQ
Sbjct: 310 -------------QGGNQPQGPPPPPGKPQGPPPQGGNK-PQGPPPPG-KPQGPPPQGGS 354
Query: 514 RDQGRRAAGAQLHDPTTQ-------PSPPTGA--QQVEEDPA 546
+ + R+ + P Q P PP G QQ + PA
Sbjct: 355 KSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPA 396
Score = 69.3 bits (168), Expect = 2e-11
Identities = 74/257 (28%), Positives = 101/257 (39%), Gaps = 32/257 (12%)
Query: 223 PPPPRPSPAPGLTGRGQGRA-RGAVGLDCGCRPRPCSFGQPDVGSAPSRSLRGCSLRFRN 281
PPPP P G + R+ R G G P P QP P +G + N
Sbjct: 153 PPPPGKPQGPPPQGDNKSRSSRSPPGKPQG--PPPQGGNQPQGPPPPPGKPQGPPPQGGN 210
Query: 282 TP--PPIPGSDQ-PSSHGRPRF---RETGDSEDCPPFRAGTPPQQPTAPSSEWPGPQRSP 335
P PP PG Q P G + R PP + G PQ P P + GP
Sbjct: 211 KPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 270
Query: 336 GTGPRWTAPLPRPAPLPAKRPGDSPASKRP--RP------GGVSPEARDPPKGEN----P 383
G P+ P +P P + S +S+ P +P GG P+ PP G+ P
Sbjct: 271 GNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 330
Query: 384 LCSSEAAGETGPTQVRGPDALGGGRLQG-KGREGKAPG----EGVSPR-PAPPRLGKP-- 435
++ G P + +GP GG + + + GK G EG +P+ P PP G P
Sbjct: 331 QGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQ 390
Query: 436 ---PRSRPPQGLAQPPE 449
P + PQG +PP+
Sbjct: 391 PQAPPAGQPQGPPRPPQ 407
Score = 68.9 bits (167), Expect = 2e-11
Identities = 87/339 (25%), Positives = 115/339 (33%), Gaps = 54/339 (15%)
Query: 227 RPSPAPGLTGRGQGRARGAVGLDCGCRPRPCSFGQPDVGSAPSRSLRGCSLRFRNTP--P 284
+P P G+ QG P P QP P +G + N P P
Sbjct: 46 KPQGPPSPPGKPQG-------------PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP 92
Query: 285 PIPGSDQ---PSSHGRPRFRETGDSEDCPPFRAGTPPQQPTAPSSEWPGPQRSPGTGPRW 341
P PG Q P R PP + G PQ P P + GP G P+
Sbjct: 93 PPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG 152
Query: 342 TAPLPRPAPLPAKRPGDSPASKRP--RP------GGVSPEARDP----PKGENPLCSSEA 389
P +P P + S +S+ P +P GG P+ P P+G P ++
Sbjct: 153 PPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 212
Query: 390 AGETGPTQVRGPDALGGGRLQ------GKGREGKAPGEGVSPRPAPPRLGKPPRSRPPQG 443
G P + +GP G + Q GK +G P G P+ PP GK P+ PPQG
Sbjct: 213 QGPPPPGKPQGPPPQGDNKSQSARSPPGK-PQGPPPQGGNQPQGPPPPPGK-PQGPPPQG 270
Query: 444 LAQPPETFFFERSRLVPVSAELERAGHGFSGDAEARS--GDLGARPASRSSLPSAPAPPA 501
+P P G S +RS G P + P P PP
Sbjct: 271 GNKPQGP--------PPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPP 322
Query: 502 QQPQAARHGAAGRDQGRRAAGAQLHDPTTQPSPPTGAQQ 540
+PQ + QG G Q PP G +
Sbjct: 323 GKPQGPPPQGGNKPQGPPPPG------KPQGPPPQGGSK 355
Score = 62.8 bits (151), Expect = 2e-09
Identities = 59/234 (25%), Positives = 81/234 (34%), Gaps = 39/234 (16%)
Query: 304 GDSEDCPPFRAGTPPQQPTAPSSEWPGPQRSPGTGPRWTAPLPRPAPLPAKRPGDSPASK 363
G+ + PP + G PQ P +P + GP G P+ P P P K G P
Sbjct: 34 GNPQGAPP-QGGNKPQGPPSPPGKPQGPPPQGGNQPQ------GPPPPPGKPQGPPPQGG 86
Query: 364 RPRPGGVSPEARDPPKGENPLCSSEAAGETGPTQVRGPDALGGGRLQGKGREGKAPGEGV 423
+P G P + P+G P + + P + +GP GG + QG P
Sbjct: 87 N-KPQGPPPPGK--PQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQG------PPPPPG 137
Query: 424 SPRPAPPRLGKPPRSRPPQGLAQPPETFFFERSRLVPVSAELERAGHGFSGDAEARSGDL 483
P+ PP+ G P+ PP G Q P G S + + G
Sbjct: 138 KPQGPPPQGGNKPQGPPPPGKPQGPPP-----------------QGDNKSRSSRSPPGKP 180
Query: 484 GARPASRSSLPSAPAPPAQQPQAARHGAAGRDQGRRAAGAQLHDPTTQPSPPTG 537
P + P P PP +PQ + QG G Q PP G
Sbjct: 181 QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG------KPQGPPPQG 228
Score = 43.9 bits (102), Expect = 8e-04
Identities = 42/134 (31%), Positives = 53/134 (39%), Gaps = 20/134 (14%)
Query: 223 PPPPRPSPAPGLTGRGQGRARGAVGLDCGCRPRPCSFGQPDVGSAPSRSLRGCSLRFRNT 282
PPP +P P G +R G G P P QP P +G + N
Sbjct: 278 PPPGKPQGPPPQGGSKSRSSRSPPGKPQG--PPPQGGNQPQGPPPPPGKPQGPPPQGGNK 335
Query: 283 P--PPIPGSDQP-------------SSHGRPRF--RETGDSEDCPPFRAGTPPQQPTAPS 325
P PP PG Q S G+P+ ++ G++ PP AG PQQP AP
Sbjct: 336 PQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP 395
Query: 326 SEWP-GPQRSPGTG 338
+ P GP R P G
Sbjct: 396 AGQPQGPPRPPQGG 409
>gi|24308163 fem-1 homolog a [Homo sapiens]
Length = 669
Score = 71.2 bits (173), Expect = 4e-12
Identities = 60/202 (29%), Positives = 93/202 (46%), Gaps = 15/202 (7%)
Query: 593 ESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVAL 652
E++ L A+ A ++ ++R+L+RRG SV T R T L AC+ G ++ V L
Sbjct: 79 ETIEGAPPLWAASAAGHLDVVRSLLRRGASVNR---TTRTNSTPLRAACFDGHLEVVRYL 135
Query: 653 AECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQ 712
D+ + G+T L+ + GH I YLL G + RR+A G TAL A
Sbjct: 136 VGEHQADLEVANRHGHTCLMISCYKGHREIARYLLE--QGAQVNRRSAKGNTALHDCAES 193
Query: 713 GRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQF-WEKY 771
G + ++ +L G GM+P A+ TG + V + + E+P EQ +
Sbjct: 194 GSLEILQ--LLLGCKARMERDGYGMTPLLAASVTGHTNIVEYL--IQEQPGQEQVAGGEA 249
Query: 772 RPELPPPPEAARKPAGSKNCLQ 793
+P LP P+ S+ C Q
Sbjct: 250 QPGLP-----QEDPSTSQGCAQ 266
Score = 39.3 bits (90), Expect = 0.019
Identities = 29/101 (28%), Positives = 46/101 (45%), Gaps = 18/101 (17%)
Query: 667 GNTALITAAQAGHAIITNYLLN------------YFPGLDLERRNAFGFTALMKAAMQGR 714
G T L+ AA+ GH + YL++ +F G +E G L A+ G
Sbjct: 41 GGTPLLIAARYGHLDVVEYLVDRCGASVEAGGSVHFDGETIE-----GAPPLWAASAAGH 95
Query: 715 TDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 755
D +R+L+ GA V+ R R +P A + G ++ VR +
Sbjct: 96 LDVVRSLLRRGASVN-RTTRTNSTPLRAACFDGHLEVVRYL 135
>gi|96975023 ankyrin repeat and death domain containing 1A [Homo
sapiens]
Length = 522
Score = 70.9 bits (172), Expect = 6e-12
Identities = 53/158 (33%), Positives = 77/158 (48%), Gaps = 8/158 (5%)
Query: 600 TLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVAL--AECPH 657
TLL A + + + D+ GRT A HG +D + L + C H
Sbjct: 126 TLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTAFHRAAEHGQLDALDFLVGSGCDH 185
Query: 658 VDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDC 717
N +D EGNTAL AA GH + L++ GLDLE +NA G TAL AA DC
Sbjct: 186 ---NVKDKEGNTALHLAAGRGHMAVLQRLVDI--GLDLEEQNAEGLTALHSAAGGSHPDC 240
Query: 718 IRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 755
++ L+ AG+ V+A ++ +S +A +G D R++
Sbjct: 241 VQLLLRAGSTVNAL-TQKNLSCLHYAALSGSEDVSRVL 277
Score = 40.4 bits (93), Expect = 0.008
Identities = 30/128 (23%), Positives = 61/128 (47%), Gaps = 5/128 (3%)
Query: 633 GRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPG 692
G L+++ + G + + L ++ + +G T L AAQ GH + +++
Sbjct: 91 GMNALLLSAWFGHLRILQILVNSG-AKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLED 149
Query: 693 LDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAV 752
+ L+ + G TA +AA G+ D + L+ +G D + +D + G + A G +
Sbjct: 150 VALDHVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKD-KEGNTALHLAAGRGH---M 205
Query: 753 RLMQRLLE 760
++QRL++
Sbjct: 206 AVLQRLVD 213
Score = 36.6 bits (83), Expect = 0.12
Identities = 30/111 (27%), Positives = 48/111 (43%), Gaps = 9/111 (8%)
Query: 658 VDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLD--------LERRNAFGFTALMKA 709
V+ ++ G AL AA AGH LL + +D E R FG AL+ +
Sbjct: 39 VNTRARNHVGRVALHWAAGAGHEQAVRLLLEHEAAVDEEDAVGALTEARLCFGMNALLLS 98
Query: 710 AMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLE 760
A G ++ L+ +GA +H + + G++ A G V + + LE
Sbjct: 99 AWFGHLRILQILVNSGAKIHC-ESKDGLTLLHCAAQKGHVPVLAFIMEDLE 148
Score = 32.7 bits (73), Expect = 1.8
Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 4/80 (5%)
Query: 608 NNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEG 667
N L+R L+ S + D +T L +A H + D + + VD+N +D +G
Sbjct: 302 NFPALVRLLIN---SDSDVNAVDNRQQTPLHLAAEHAWQD-IADMLLIAGVDLNLRDKQG 357
Query: 668 NTALITAAQAGHAIITNYLL 687
TAL A ++ H + + ++
Sbjct: 358 KTALAVAVRSNHVSLVDMII 377
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 68.2 bits (165), Expect = 4e-11
Identities = 75/273 (27%), Positives = 98/273 (35%), Gaps = 48/273 (17%)
Query: 187 GRERTSAPLRRDLPPRLAHDASYPEVKGSLWQILTRPPPPRPSPAPGLTGRGQGRARGAV 246
G+ P + P R PE + ++ PPPRP G +G +++G
Sbjct: 34 GKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPP 93
Query: 247 GLDCGCRPRPCS-FGQPDVGSAPSRSLRGCSLRFRNTPPPIPGSDQPSSHGRPRFRETGD 305
PRP GQP G S+ PPP PG + G P + G+
Sbjct: 94 -------PRPGKPEGQPPQGGNQSQG-----------PPPRPGKPE----GPPP--QGGN 129
Query: 306 SEDCPPFRAGTPPQQPTAPSSEWPGPQRSPGTG----PRWTAPLPRPAPLPAKRPGDSPA 361
PP R G P P ++ GP PG P+ P P P K G P
Sbjct: 130 QSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQ 189
Query: 362 SKR------PRPGGVSPEARDPPKGENPLCSSEAAGETGPTQVRGPDALGGGRLQGKGRE 415
PRPG PE PP+G N P + GP + GG + QG
Sbjct: 190 GGNQSQGPPPRPG--KPEG-PPPQGGN----QSQGPPPRPGKPEGPPSQGGNKPQGP--- 239
Query: 416 GKAPGEGVSPRPAPPRLGKPPRSRPPQGLAQPP 448
P P+ PP+ G P+ PP G Q P
Sbjct: 240 ---PPHPGKPQGPPPQEGNKPQRPPPPGRPQGP 269
Score = 67.0 bits (162), Expect = 8e-11
Identities = 88/315 (27%), Positives = 118/315 (37%), Gaps = 67/315 (21%)
Query: 163 GGKKGRKEARGTQGW-WPPQSLTCDGRERTSAPLRRDLPPRLAHDASYPEVKGSLWQILT 221
G +GR+ G Q PP +GR + PPR P G+ Q
Sbjct: 34 GKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQ--- 90
Query: 222 RPPPPRPSPAPGLTGRGQGRARGAVGLDCGCRPRPCSFGQPDVGSAPSRSLRGCSLRFRN 281
PPPRP G +G +++G PRP G+P+ G P +
Sbjct: 91 -GPPPRPGKPEGQPPQGGNQSQGPP-------PRP---GKPE-GPPPQGGNQS------Q 132
Query: 282 TPPPIPGSDQPSSHGRPRFRETGDSEDCPPFRAGTPPQQPTAPSSEWPGPQRSPGT---- 337
PPP PG + G P + G+ PP R G P P ++ GP PG
Sbjct: 133 GPPPRPGKPE----GPPP--QGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGP 186
Query: 338 ----GPRWTAPLPRPAPL--PAKRPGDSPASKRPRPG---GVSPEARDPPKGENPLCSSE 388
G + P PRP P + G+ PRPG G + + P+G P
Sbjct: 187 PPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPP----- 241
Query: 389 AAGETGPTQVRGPDALGGGRLQGK---GR-EGKAPGEGVSPRPAPPRLGK------PPRS 438
P + +GP G + Q GR +G P G +P PP GK PP+
Sbjct: 242 -----HPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQG 296
Query: 439 ----RPPQGLAQPPE 449
RPPQG QPP+
Sbjct: 297 GRPHRPPQG--QPPQ 309
Score = 64.7 bits (156), Expect = 4e-10
Identities = 82/276 (29%), Positives = 100/276 (36%), Gaps = 35/276 (12%)
Query: 280 RNTPPPIPGSDQPSSHGRPRFRETGDSEDCPPFRAGTPPQQPTAPSSEWPGPQRSPGT-- 337
+ TPPP PG + GRP + G+ PP R G P P ++ GP PG
Sbjct: 48 QRTPPP-PGKPE----GRPP--QGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPE 100
Query: 338 ------GPRWTAPLPRPAPLPAKRPGDSPASKRPRPGGVSPEARDPPKGENPLCSSEAAG 391
G + P PRP P S+ P P PE PP+G N
Sbjct: 101 GQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEG-PPPQGGN----QSQGP 155
Query: 392 ETGPTQVRGPDALGGGRLQGK----GR-EGKAPGEGVSPRPAPPRLGKPPRSRPPQGLAQ 446
P + GP GG + QG G+ EG P G + PPR GKP PPQG Q
Sbjct: 156 PPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKP-EGPPPQGGNQ 214
Query: 447 ----PPETFFFERSRLVPVSAELERAGH-GFSGDAEARSGDLGARPASRSSLPSAPAPPA 501
PP E + H G + G+ RP P P PP
Sbjct: 215 SQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGR-PQGPPPPG 273
Query: 502 QQPQAARHGAAGRDQG--RRAAGAQLHDPTTQPSPP 535
PQ AG+ QG G + H P Q PP
Sbjct: 274 GNPQQPLPPPAGKPQGPPPPPQGGRPHRP-PQGQPP 308
Score = 47.4 bits (111), Expect = 7e-05
Identities = 68/271 (25%), Positives = 89/271 (32%), Gaps = 48/271 (17%)
Query: 319 QQPTAPSSEWPGPQRSPGTGPRWTAPLP---------------RPAPLPAKRPGDSP--- 360
+ P+ S + G + G P+ T P P P P P K G P
Sbjct: 27 ESPSVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGG 86
Query: 361 -ASKRPRPGGVSPEARDP---------------PKGENPLCSSEAAG-ETGPTQVRGPDA 403
S+ P P PE + P P+G P +++ G P + GP
Sbjct: 87 NQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPP 146
Query: 404 LGGGRLQG----KGR-EGKAPGEGVSPRPAPPRLGKPPRSRPPQG--LAQPPETFFFERS 456
GG + QG G+ EG P G + PP GK P PPQG +Q P +
Sbjct: 147 QGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGK-PEGPPPQGGNQSQGPPPRPGKPE 205
Query: 457 RLVPVSAELERAGHGFSGDAEARSGDLGARPASRSSLPSAP--APPAQQPQAARHGAAGR 514
P + G E G +P P P PP + + R GR
Sbjct: 206 GPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGR 265
Query: 515 DQGRRAAGAQLHDPTTQPSPPTGAQQVEEDP 545
QG G P PP G Q P
Sbjct: 266 PQGPPPPGGNPQQPL---PPPAGKPQGPPPP 293
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 67.4 bits (163), Expect = 6e-11
Identities = 101/379 (26%), Positives = 141/379 (37%), Gaps = 67/379 (17%)
Query: 189 ERTSAPLRRDLPPRLAHDASYPEVKGSL-WQILTRPPPPRPS---PAPGLTGRGQGRARG 244
ERT A L + + R SY KGS+ ++ R PPR PAP RG A
Sbjct: 67 ERTRAELEKLIQQRAVLRVSY---KGSISYRNAARVQPPRRGATPPAPPRAPRGAPAAAA 123
Query: 245 AVGLDCGCRPRPCSFGQPDVGSAPSRSLRGCSLRFRNTPPPIPGSDQPSSHGRPRFRETG 304
A P P P +AP+R+ R + T PP PG QP PR +
Sbjct: 124 AAAPPPTPAPPPPP--APVAAAAPARAPRAAAA--AATAPPSPGPAQPG----PRAQRAA 175
Query: 305 DSEDCPPFRAGTPPQQPTAPSSEWPGPQRSPGTGPRWTAPLPRPAPLPAKRPGDSPASKR 364
PP A P P A GP+R+P P A P P P +P P ++
Sbjct: 176 PLAAPPPAPAAPPAVAPPA------GPRRAP---PPAVAAREPPLP-PPPQPPAPPQQQQ 225
Query: 365 PRPGGVSPEARDPPKGENPLCSSEAAGETGPTQVR-------GPDALGG----GRLQGKG 413
P P P+ + PP+G + A G P +R G GG GR+QG
Sbjct: 226 PPP----PQPQPPPEGG----AVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGL- 276
Query: 414 REGKAPGEGVSPRPAPPRLGKPPRSRPPQGLAQPPETFFFERSRLVPVSAELERAGHGFS 473
E +A G R L P RP G A P + RS+ LE+
Sbjct: 277 LEEEAAARGRLERTRLGALALPRGDRP--GRAPPAASARPSRSKRGGEERVLEKEEEEDD 334
Query: 474 GDAEARSGDLGARPASRSSLPSAPAPPAQQPQAARHGAAGRDQGRRAAGAQL-------- 525
+ E D+ + P + +P A+H ++G ++A ++
Sbjct: 335 DEDEDEEDDVS---------EGSEVPESDRPAGAQHHQLNGERGPQSAKERVKEWTPCGP 385
Query: 526 ---HDPTTQPSPPTGAQQV 541
D P+P +G +QV
Sbjct: 386 HQGQDEGRGPAPGSGTRQV 404
Score = 55.1 bits (131), Expect = 3e-07
Identities = 80/308 (25%), Positives = 112/308 (36%), Gaps = 47/308 (15%)
Query: 310 PPFRAGTPPQQPTAPSSEWPGPQRSPGTGPRWT-APLPRPAPLPAKRPGDSP------AS 362
PP R TPP P AP P + P T AP P PAP+ A P +P A+
Sbjct: 101 PPRRGATPPAPPRAPRG---APAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAAT 157
Query: 363 KRPRPGGVSPEARDPPKGENPLCSSEAAGETGPTQVRGPDALGGGRLQGKGREGKAPGEG 422
P PG P R + PL + A P V P G R + P
Sbjct: 158 APPSPGPAQPGPR--AQRAAPLAAPPPA-PAAPPAVAPP--AGPRRAPPPAVAAREP--- 209
Query: 423 VSPRPAPPRLGKPP-RSRPPQGLAQPPETFFFERS--RLVPVSAELERAGHGFSGDAEAR 479
P P PP+ PP + +PP QPP R+ PVS G SG A R
Sbjct: 210 --PLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGR 267
Query: 480 ------SGDLGARPAS-----RSSLPSAPAPPAQQPQAARHGAAGRDQGRRAAGAQLHDP 528
G L A+ R+ L + P +P A A+ R + G +
Sbjct: 268 LTRGRVQGLLEEEAAARGRLERTRLGALALPRGDRPGRAPPAASARPSRSKRGGEE---- 323
Query: 529 TTQPSPPTGAQQVEEDPADYEEFEDILESARHPQASHSDDSFYPFEDEEEHGVESAESVP 588
++ E+D D +E +D+ E + P++ + + + +G +S
Sbjct: 324 -----RVLEKEEEEDDDEDEDEEDDVSEGSEVPESDRPAGA----QHHQLNGERGPQSAK 374
Query: 589 EGVPESVP 596
E V E P
Sbjct: 375 ERVKEWTP 382
Score = 30.4 bits (67), Expect = 8.7
Identities = 20/62 (32%), Positives = 22/62 (35%), Gaps = 2/62 (3%)
Query: 894 SPRAGLPPALG--SRGPAAPAPRKASLLPLQRLRRRSVRPGVVVPRVRVSKAPAPTFQPE 951
+PRA A S GPA P PR PL P V P +AP P
Sbjct: 148 APRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAR 207
Query: 952 RP 953
P
Sbjct: 208 EP 209
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 66.6 bits (161), Expect = 1e-10
Identities = 74/235 (31%), Positives = 83/235 (35%), Gaps = 21/235 (8%)
Query: 223 PPPPRPS----PAPGLTGRGQGRARGAVGLDCGCRPRPCSFGQPDVGSAPSRSLRGCSLR 278
PPPP P P P L G G G G P P P G P L G +
Sbjct: 944 PPPPLPGAAIPPPPPLPGAGIPLPPPLPG--AGIPPPP---PLPGAGIPPPPPLPGAGIP 998
Query: 279 FRNTPPPIPGSDQPSSHGRPRFRETGDSEDCPPFRAGTPPQQPTAPSSEWPGPQRSPGTG 338
PPP+PG+ P P G P AG PP P P + P P PG G
Sbjct: 999 ---PPPPLPGAGIPPP---PPLPGAGIPPPPPLPGAGIPPPPPL-PGAGIPPPPPLPGAG 1051
Query: 339 PRWTAPLPRPA-PLPAKRPGDSPASKRPRPG-GVSPEARDPPKGENPLCSSEAAGETGPT 396
PLP P P PG P PG G+ P P G P G P
Sbjct: 1052 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPP 1111
Query: 397 QVRGPDALGGGRLQGKG--REGKAPGEGVSPRPAPPRLG-KPPRSRPPQGLAQPP 448
+ G L G G PG G+ P P PR+G PP P G+ PP
Sbjct: 1112 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPP 1166
Score = 64.7 bits (156), Expect = 4e-10
Identities = 75/240 (31%), Positives = 83/240 (34%), Gaps = 27/240 (11%)
Query: 223 PPPPRPS----PAPGLTGRGQGRARGAVGLDCGCRPRPCSFGQPDVGSAPSRSLRGCSLR 278
PPPP P P P L G G G G P P P G P L G +
Sbjct: 1010 PPPPLPGAGIPPPPPLPGAGIPPPPPLPG--AGIPPPP---PLPGAGIPPPPPLPGAGIP 1064
Query: 279 FRNTPPPIPGSDQPSSHGRPRFRETGDSEDCPPFRAGTPPQQPTAPSSEWPGPQRSPGTG 338
PPP+PG+ P P G P AG PP P P P P PG G
Sbjct: 1065 ---PPPPLPGAGIPPP---PPLPGAGIPPPPPLPGAGIPPPPPL-PGVGIPPPPPLPGAG 1117
Query: 339 PRWTAPLPR---PAPLPAKRPGDSPASKRPRPGGVSPEARDPPKGENPLCSSEAAGETGP 395
PLP P P P G P PR G + P P G P AG P
Sbjct: 1118 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVG-IPPPPPLPGAGIPPPPPLPGAGIPPP 1176
Query: 396 TQVRGPDALGGGRLQGKG--REGKAPGEGVSPRPAPPRLGKPPRSRPP-----QGLAQPP 448
+ G L G G PG G+ P P P +G PP PP G+ PP
Sbjct: 1177 PPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPP 1236
Score = 63.2 bits (152), Expect = 1e-09
Identities = 69/231 (29%), Positives = 81/231 (35%), Gaps = 22/231 (9%)
Query: 223 PPPPRPSPAPGLTGRGQGRARGAVGLDCGCRPRPCSFGQPDVGSAPSRSLRGCSLRFRNT 282
PPPP P P G+ G + L P G P L G ++
Sbjct: 909 PPPPPPLPGAGIPPPPPLPGAGILPLP----------PLPGAGIPPPPPLPGAAI---PP 955
Query: 283 PPPIPGSDQPSSHGRPRFRETGDSEDCPPFRAGTPPQQPTAPSSEWPGPQRSPGTGPRWT 342
PPP+PG+ P P G P AG PP P P + P P PG G
Sbjct: 956 PPPLPGAGIPLP---PPLPGAGIPPPPPLPGAGIPP-PPPLPGAGIPPPPPLPGAGIPPP 1011
Query: 343 APLPRPA-PLPAKRPGDSPASKRPRPG-GVSPEARDPPKGENPLCSSEAAGETGPTQVRG 400
PLP P P PG P PG G+ P P G P AG P + G
Sbjct: 1012 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1071
Query: 401 PDALGGGRLQGKG--REGKAPGEGVSPRPAPPRLG-KPPRSRPPQGLAQPP 448
L G G PG G+ P P P +G PP P G+ PP
Sbjct: 1072 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPP 1122
Score = 57.8 bits (138), Expect = 5e-08
Identities = 69/225 (30%), Positives = 76/225 (33%), Gaps = 24/225 (10%)
Query: 223 PPPPRPS----PAPGLTGRGQGRARGAVGLDCGCRPRPCSFGQPDVGSAPSRSLRGCSLR 278
PPPP P P P L G G G G P P P G P L G +
Sbjct: 1032 PPPPLPGAGIPPPPPLPGAGIPPPPPLPG--AGIPPPP---PLPGAGIPPPPPLPGAGIP 1086
Query: 279 FRNTPPPIPGSDQPSSHGRPRFRETGDSEDCPPFRAGTPPQQPTAPSSEWPGPQRSPGTG 338
PPP+PG+ P P G P AG PP P P + P P PG G
Sbjct: 1087 ---PPPPLPGAGIPPP---PPLPGVGIPPPPPLPGAGIPPPPPL-PGAGIPPPPPLPGAG 1139
Query: 339 PRWTAPLPRPA-PLPAKRPGDSPASKRPRPG-GVSPEARDPPKGENPLCSSEAAGETGPT 396
PLPR P P PG P PG G+ P P G P G P
Sbjct: 1140 IPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPP 1199
Query: 397 QVRG------PDALGGGRLQGKGREGKAPGEGVSPRPAPPRLGKP 435
+ G P G G PG G+ P P P G P
Sbjct: 1200 PLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPP 1244
Score = 57.4 bits (137), Expect = 7e-08
Identities = 63/229 (27%), Positives = 75/229 (32%), Gaps = 32/229 (13%)
Query: 225 PPRPSPAPGLTGRGQGRARGAVGLDCGCRPRPCSFGQPDVGSAPSRSLRGCSLRFRNTPP 284
PP P P PG+T L P+P ++ P L G + PP
Sbjct: 877 PPPPPPLPGMT---------VPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGI---PPPP 924
Query: 285 PIPGSDQPSSHGRPRFRETGDSEDCPPFRAGTPPQQPTAPSSEWPGPQRSPGTGPRWTAP 344
P+PG+ PP P P P + P P PG G P
Sbjct: 925 PLPGA---------------GILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPP 969
Query: 345 LPRPA-PLPAKRPGDSPASKRPRPG-GVSPEARDPPKGENPLCSSEAAGETGPTQVRGPD 402
LP P P PG P PG G+ P P G P AG P + G
Sbjct: 970 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1029
Query: 403 ALGGGRLQGKG--REGKAPGEGVSPRPAPPRLG-KPPRSRPPQGLAQPP 448
L G G PG G+ P P P G PP P G+ PP
Sbjct: 1030 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1078
Score = 55.1 bits (131), Expect = 3e-07
Identities = 65/219 (29%), Positives = 75/219 (34%), Gaps = 46/219 (21%)
Query: 254 PRPC---SFGQPDVGSAPSRSLRGCSLRFRNTPPPIPGSDQPS--SHGRPRFRETGDSED 308
P PC S P +G P PPP+PG P+ S P+
Sbjct: 860 PLPCTESSSSMPGLGMVPP------------PPPPLPGMTVPTLPSTAIPQ--------- 898
Query: 309 CPPFRAGT---PPQQPTAPSSEWPGPQRSPGTG-----PRWTAPLPRPAPLPAKR----- 355
PP GT PP P P + P P PG G P A +P P PLP
Sbjct: 899 -PPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPP 957
Query: 356 --PGDSPASKRPRPG-GVSPEARDPPKGENPLCSSEAAGETGPTQVRGPDALGGGRLQGK 412
PG P PG G+ P P G P AG P + G L G
Sbjct: 958 PLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1017
Query: 413 G--REGKAPGEGVSPRPAPPRLG-KPPRSRPPQGLAQPP 448
G PG G+ P P P G PP P G+ PP
Sbjct: 1018 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1056
Score = 51.2 bits (121), Expect = 5e-06
Identities = 68/216 (31%), Positives = 75/216 (34%), Gaps = 45/216 (20%)
Query: 223 PPPPRPS----PAPGLTGRGQGRARGAVGLDCGCRPRPCSFGQPDVGSAPSRSLRGCSLR 278
PPPP P P P L G G G G P P P VG P L G +
Sbjct: 1109 PPPPLPGAGIPPPPPLPGAGIPPPPPLPG--AGIPPPP---PLPRVGIPPPPPLPGAGIP 1163
Query: 279 FRNTPPPIPGSDQPSSHGRPRFRETGDSEDCPPFRAGTPPQQPTAPSSEWPGPQRSPGTG 338
PPP+PG+ P PP P P P P P PG G
Sbjct: 1164 ---PPPPLPGAGIPPP---------------PPLPGVGIPPPPPLPGVGIPPPPPLPGAG 1205
Query: 339 PRWTAPLPRPAPLPAKRPGDSPASKRPRPG-GVSPEARDPPKGENPLCSSEAAGETGPT- 396
+P P PLP +PA P PG G+ P P G P + T PT
Sbjct: 1206 ------IPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSG--PPLLPQVGSSTLPTP 1257
Query: 397 QVRG------PDALGG-GRLQGKGREGKAPGEGVSP 425
QV G P L G G Q KG K P E P
Sbjct: 1258 QVCGFLPPPLPSGLFGLGMNQDKGSR-KQPIEPCRP 1292
Score = 35.4 bits (80), Expect = 0.27
Identities = 43/155 (27%), Positives = 50/155 (32%), Gaps = 33/155 (21%)
Query: 319 QQPTAPSSEWPGPQRSPGTGP--------------------RWTAPLPRPAPLPAKRPGD 358
Q P PS W Q PG+ P + + +P P PLP
Sbjct: 809 QPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTES-- 866
Query: 359 SPASKRPRPGGVSPEARDPPKGENPLCSSEAAGETGPTQVRG-----PDALGGGRLQGKG 413
+S P G V P P P S A + P Q P L G G
Sbjct: 867 --SSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGA---GIP 921
Query: 414 REGKAPGEGVSPRPAPPRLGKPPRSRPPQGLAQPP 448
PG G+ P P P G PP P G A PP
Sbjct: 922 PPPPLPGAGILPLPPLPGAGIPP-PPPLPGAAIPP 955
Score = 34.3 bits (77), Expect = 0.61
Identities = 38/135 (28%), Positives = 51/135 (37%), Gaps = 27/135 (20%)
Query: 321 PTAPSSEWPGPQRSPGTGPRWTAPLPRPAPLPAK--------RPGDSPASKRPRPGGVSP 372
P+ + E PG SP T +A P L A+ PG P S+ P P
Sbjct: 256 PSGGAGEAPG---SPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQP 312
Query: 373 EARDPPKGENPLCSSEAAGETGP-TQVRGPDALGGGRLQGKGREGK-------APGEGVS 424
A+D P ++ E GP + G G G +G E +PGE +
Sbjct: 313 AAKDSPSS-----TAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWA 367
Query: 425 P---RPAPPRLGKPP 436
P AP RLG+ P
Sbjct: 368 PEVGEDAPQRLGEEP 382
Score = 32.3 bits (72), Expect = 2.3
Identities = 48/193 (24%), Positives = 63/193 (32%), Gaps = 33/193 (17%)
Query: 224 PPPRPSPAPGLTGRGQGRARGAVGLDCGCRPRPCSFGQPDVGSAPSRSLRGCSLRFRNTP 283
PP SP PG G R +G G P G PD A S L
Sbjct: 235 PPTAVSPQPGAF---LGLDRFLLGPSGGAGEAP---GSPDTEQALSAL---SDLPESLAA 285
Query: 284 PPIPGSDQPSSHGRPRFRETGDSEDCPPFRAGTPPQQPTAPSSEWPGPQRSPGTGPRWTA 343
P PS G P + P A P + + S+ +P P+ PG
Sbjct: 286 EPREPQQPPSPGGLP-------VSEAPSLPAAQPAAKDSPSSTAFPFPEAGPG------- 331
Query: 344 PLPRPAPLPAKRPGDSPA-----SKRPRPGGVSPEARDPPKGENPLCSSEAAGETGPTQV 398
A P + GD+ + P G E P GE+ + + GE +
Sbjct: 332 --EEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGED---APQRLGEEPEEEA 386
Query: 399 RGPDALGGGRLQG 411
+GPDA L G
Sbjct: 387 QGPDAPAAASLPG 399
>gi|169208819 PREDICTED: similar to kinase D-interacting substrate
220 [Homo sapiens]
Length = 380
Score = 66.2 bits (160), Expect = 1e-10
Identities = 86/315 (27%), Positives = 124/315 (39%), Gaps = 28/315 (8%)
Query: 613 LRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALI 672
+R L+ +G +V D GRT L +AC G +D V L + D DS GN+ ++
Sbjct: 67 VRLLLEQGAAVNLR---DERGRTALSLACERGHLDAVQLLVQFSG-DPEAADSAGNSPVM 122
Query: 673 TAAQAGHAIITNYLLNYFP--GLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHA 730
AA GH + +L+ F GL L+R N G TAL AA +G C++AL A
Sbjct: 123 WAAACGHGAVLEFLVRSFRRLGLRLDRTNRAGLTALQLAAARGHGTCVQALTGPWGRAAA 182
Query: 731 RDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARKPAGSKN 790
RG + + GR + RP P + RP L AA G
Sbjct: 183 AAAARGSNSD---SPPGRPAPAASPEH--RRPSPRRL---PRPLLARFARAAGGHGGEAG 234
Query: 791 CLQRLTDCVLSVLTPRSVRGPEDGGVLDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKR 850
+ + + + R PE G + + T + + P SP S G
Sbjct: 235 SAGKNSGRHRAQGSER----PELGRSMSLALGAVTEEEAARLRAGALMALPNSPQSSGTG 290
Query: 851 RLAVQEILAA---RAARGPQAQEEDEVGGAGQRGRTGQEDADSREGSPRAGLPPALG-SR 906
R QE+L A+ P GG G GR G R S +P +G +
Sbjct: 291 RWRSQEVLEGAPPTLAQAPIGLSPHPEGGPGS-GRLG-----LRRRSTAPDIPSLVGEAP 344
Query: 907 GPAAPAPRKASLLPL 921
GP + +A+ LP+
Sbjct: 345 GPESGPELEANALPV 359
Score = 39.3 bits (90), Expect = 0.019
Identities = 56/187 (29%), Positives = 74/187 (39%), Gaps = 31/187 (16%)
Query: 187 GRERTSAPLR---RDLPPRLAHDASYPEVKGSLWQILTRPPPPRPSPAPGLTGRGQGRAR 243
GR +A R D PP A+ PE + + L RP R + A G G G
Sbjct: 178 GRAAAAAAARGSNSDSPPGRPAPAASPEHRRPSPRRLPRPLLARFARAAG----GHGGEA 233
Query: 244 GAVGLDCGCRPRPCSFGQPDVGSAPSRSLRGCS----LRFR-NTPPPIPGSDQPSSHGRP 298
G+ G + G R R +P++G + S +L + R R +P S Q S GR
Sbjct: 234 GSAGKNSG-RHRAQGSERPELGRSMSLALGAVTEEEAARLRAGALMALPNSPQSSGTGRW 292
Query: 299 RFRETGDSEDCPPFRAGTPPQQPTAPSSEWPGPQRSPGTG-----PRWTAP----LPRPA 349
R +E + G PP AP P P+ PG+G R TAP L A
Sbjct: 293 RSQEVLE---------GAPPTLAQAPIGLSPHPEGGPGSGRLGLRRRSTAPDIPSLVGEA 343
Query: 350 PLPAKRP 356
P P P
Sbjct: 344 PGPESGP 350
>gi|169208593 PREDICTED: similar to kinase D-interacting substrate
220 [Homo sapiens]
Length = 380
Score = 66.2 bits (160), Expect = 1e-10
Identities = 86/315 (27%), Positives = 124/315 (39%), Gaps = 28/315 (8%)
Query: 613 LRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALI 672
+R L+ +G +V D GRT L +AC G +D V L + D DS GN+ ++
Sbjct: 67 VRLLLEQGAAVNLR---DERGRTALSLACERGHLDAVQLLVQFSG-DPEAADSAGNSPVM 122
Query: 673 TAAQAGHAIITNYLLNYFP--GLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHA 730
AA GH + +L+ F GL L+R N G TAL AA +G C++AL A
Sbjct: 123 WAAACGHGAVLEFLVRSFRRLGLRLDRTNRAGLTALQLAAARGHGTCVQALTGPWGRAAA 182
Query: 731 RDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARKPAGSKN 790
RG + + GR + RP P + RP L AA G
Sbjct: 183 AAAARGSNSD---SPPGRPAPAASPEH--RRPSPRRL---PRPLLARFARAAGGHGGEAG 234
Query: 791 CLQRLTDCVLSVLTPRSVRGPEDGGVLDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKR 850
+ + + + R PE G + + T + + P SP S G
Sbjct: 235 SAGKNSGRHRAQGSER----PELGRSMSLALGAVTEEEAARLRAGALMALPNSPQSSGTG 290
Query: 851 RLAVQEILAA---RAARGPQAQEEDEVGGAGQRGRTGQEDADSREGSPRAGLPPALG-SR 906
R QE+L A+ P GG G GR G R S +P +G +
Sbjct: 291 RWRSQEVLEGAPPTLAQAPIGLSPHPEGGPGS-GRLG-----LRRRSTAPDIPSLVGEAP 344
Query: 907 GPAAPAPRKASLLPL 921
GP + +A+ LP+
Sbjct: 345 GPESGPELEANALPV 359
Score = 39.3 bits (90), Expect = 0.019
Identities = 56/187 (29%), Positives = 74/187 (39%), Gaps = 31/187 (16%)
Query: 187 GRERTSAPLR---RDLPPRLAHDASYPEVKGSLWQILTRPPPPRPSPAPGLTGRGQGRAR 243
GR +A R D PP A+ PE + + L RP R + A G G G
Sbjct: 178 GRAAAAAAARGSNSDSPPGRPAPAASPEHRRPSPRRLPRPLLARFARAAG----GHGGEA 233
Query: 244 GAVGLDCGCRPRPCSFGQPDVGSAPSRSLRGCS----LRFR-NTPPPIPGSDQPSSHGRP 298
G+ G + G R R +P++G + S +L + R R +P S Q S GR
Sbjct: 234 GSAGKNSG-RHRAQGSERPELGRSMSLALGAVTEEEAARLRAGALMALPNSPQSSGTGRW 292
Query: 299 RFRETGDSEDCPPFRAGTPPQQPTAPSSEWPGPQRSPGTG-----PRWTAP----LPRPA 349
R +E + G PP AP P P+ PG+G R TAP L A
Sbjct: 293 RSQEVLE---------GAPPTLAQAPIGLSPHPEGGPGSGRLGLRRRSTAPDIPSLVGEA 343
Query: 350 PLPAKRP 356
P P P
Sbjct: 344 PGPESGP 350
>gi|55741641 kinase D-interacting substrate of 220 kDa [Homo
sapiens]
Length = 1771
Score = 66.2 bits (160), Expect = 1e-10
Identities = 61/187 (32%), Positives = 91/187 (48%), Gaps = 14/187 (7%)
Query: 609 NVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGN 668
N+ L+ L+ + V+E E G+T L++A G ++ V L + + N +D +
Sbjct: 17 NIPALKALLEKCKDVDERNEC---GQTPLMIAAEQGNLEIVKELIK-NGANCNLEDLDNW 72
Query: 669 TALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADV 728
TALI+A++ GH I LL G++LE R+ G+TALM A +GRTD + L+ GA+
Sbjct: 73 TALISASKEGHVHIVEELLKC--GVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGANP 130
Query: 729 HARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARKPAGS 788
+ P WA G D V L LL+ +KY P AARK G
Sbjct: 131 SVTG-LYSVYPIIWAAGRGHADIVHL---LLQNGAKVNCSDKY--GTTPLVWAARK--GH 182
Query: 789 KNCLQRL 795
C++ L
Sbjct: 183 LECVKHL 189
Score = 56.2 bits (134), Expect = 1e-07
Identities = 46/156 (29%), Positives = 76/156 (48%), Gaps = 7/156 (4%)
Query: 598 TATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPH 657
T L+ AA ++ ++ L+ G V++ N T LIVA G+ +V + + +
Sbjct: 171 TTPLVWAARKGHLECVKHLLAMGADVDQE---GANSMTALIVAVKGGYTQSVKEILK-RN 226
Query: 658 VDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDC 717
+VN D +GNTAL+ A++ GH I LL+ +++ R+ G T L+ A G +
Sbjct: 227 PNVNLTDKDGNTALMIASKEGHTEIVQDLLDAGTYVNIPDRS--GDTVLIGAVRGGHVEI 284
Query: 718 IRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVR 753
+RAL+ AD+ R + + WA G VR
Sbjct: 285 VRALLQKYADIDIRG-QDNKTALYWAVEKGNATMVR 319
Score = 52.4 bits (124), Expect = 2e-06
Identities = 43/137 (31%), Positives = 68/137 (49%), Gaps = 8/137 (5%)
Query: 593 ESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTV-VA 651
E + L+ A+ +V ++ L++ GV++E D G T L+ ACY G D V +
Sbjct: 67 EDLDNWTALISASKEGHVHIVEELLKCGVNLEHR---DMGGWTALMWACYKGRTDVVELL 123
Query: 652 LAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAM 711
L+ + V S +I AA GHA I + LL G + + +G T L+ AA
Sbjct: 124 LSHGANPSVTGLYSV--YPIIWAAGRGHADIVHLLLQN--GAKVNCSDKYGTTPLVWAAR 179
Query: 712 QGRTDCIRALMLAGADV 728
+G +C++ L+ GADV
Sbjct: 180 KGHLECVKHLLAMGADV 196
Score = 44.3 bits (103), Expect = 6e-04
Identities = 42/133 (31%), Positives = 64/133 (48%), Gaps = 7/133 (5%)
Query: 630 DRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNY 689
DR+G T LI A G V+ V AL + + D++ + + TAL A + G+A + +L
Sbjct: 266 DRSGDTVLIGAVRGGHVEIVRALLQ-KYADIDIRGQDNKTALYWAVEKGNATMVRDILQC 324
Query: 690 FPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRV 749
P D E G T L+KA + + L+ GA V A D ++G +P A R
Sbjct: 325 NP--DTEICTKDGETPLIKATKMRNIEVVELLLDKGAKVSAVD-KKGDTPLHIAI---RG 378
Query: 750 DAVRLMQRLLERP 762
+ +L + LL P
Sbjct: 379 RSRKLAELLLRNP 391
>gi|46519154 ankyrin repeat and KH domain containing 1 isoform 3
[Homo sapiens]
Length = 627
Score = 65.5 bits (158), Expect = 2e-10
Identities = 57/182 (31%), Positives = 80/182 (43%), Gaps = 6/182 (3%)
Query: 575 DEEEHGVESAESVPEGVPESVPETATLLRAAC-ANNVGLLRTLVRRGVSVEEAQETDRNG 633
D + + V V E E +LL AC A L + L+ +VE+ ++
Sbjct: 215 DGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVED--RGNKGD 272
Query: 634 RTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGL 693
T L+ A G++D +V L DVN Q + GNTAL A G I LLN G
Sbjct: 273 ITPLMAASSGGYLD-IVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLN--EGA 329
Query: 694 DLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVR 753
++E N G T LM+AA G + R L+ GA ++ S A Y G +D VR
Sbjct: 330 NIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVR 389
Query: 754 LM 755
+
Sbjct: 390 FL 391
Score = 60.1 bits (144), Expect = 1e-08
Identities = 46/155 (29%), Positives = 71/155 (45%), Gaps = 6/155 (3%)
Query: 601 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 660
L+ A+ + +++ L+ V T G T L AC GFVD V L ++
Sbjct: 276 LMAASSGGYLDIVKLLLLHDADVNSQSAT---GNTALTYACAGGFVDIVKVLLN-EGANI 331
Query: 661 NWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRA 720
+ G+T L+ AA AGH + LL++ G++ N F +AL A +G D +R
Sbjct: 332 EDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHS-NEFKESALTLACYKGHLDMVRF 390
Query: 721 LMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 755
L+ AGAD + + E A G V+ RL+
Sbjct: 391 LLEAGADQEHKTDEMHTALME-ACMDGHVEVARLL 424
Score = 54.3 bits (129), Expect = 6e-07
Identities = 42/131 (32%), Positives = 68/131 (51%), Gaps = 10/131 (7%)
Query: 601 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 660
L AAC +V L L+ RG ++EE + G T L+ A G + +VAL ++
Sbjct: 442 LTLAACGGHVELAALLIERGANLEEVND---EGYTPLMEAAREGH-EEMVALLLAQGANI 497
Query: 661 NWQDSEGN-TALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIR 719
N Q E TAL A G + + ++L+ G D+E + T LM+A+ +G + ++
Sbjct: 498 NAQTEETQETALTLACCGGFSEVADFLIK--AGADIELGCS---TPLMEASQEGHLELVK 552
Query: 720 ALMLAGADVHA 730
L+ +GA+VHA
Sbjct: 553 YLLASGANVHA 563
Score = 50.1 bits (118), Expect = 1e-05
Identities = 42/162 (25%), Positives = 68/162 (41%), Gaps = 34/162 (20%)
Query: 601 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 660
L+ AA A +V + R L+ G + ++ + L +ACY G +D V L E D
Sbjct: 342 LMEAASAGHVEVARVLLDHGAGINT--HSNEFKESALTLACYKGHLDMVRFLLEAG-ADQ 398
Query: 661 NWQDSEGNTALITAAQAGHAIITNYLLNYFP----------------------------- 691
+ E +TAL+ A GH + LL+
Sbjct: 399 EHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLI 458
Query: 692 --GLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHAR 731
G +LE N G+T LM+AA +G + + L+ GA+++A+
Sbjct: 459 ERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQ 500
>gi|46519151 ankyrin repeat and KH domain containing 1 isoform 2
[Homo sapiens]
Length = 616
Score = 65.5 bits (158), Expect = 2e-10
Identities = 57/182 (31%), Positives = 80/182 (43%), Gaps = 6/182 (3%)
Query: 575 DEEEHGVESAESVPEGVPESVPETATLLRAAC-ANNVGLLRTLVRRGVSVEEAQETDRNG 633
D + + V V E E +LL AC A L + L+ +VE+ ++
Sbjct: 204 DGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVED--RGNKGD 261
Query: 634 RTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGL 693
T L+ A G++D +V L DVN Q + GNTAL A G I LLN G
Sbjct: 262 ITPLMAASSGGYLD-IVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLN--EGA 318
Query: 694 DLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVR 753
++E N G T LM+AA G + R L+ GA ++ S A Y G +D VR
Sbjct: 319 NIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVR 378
Query: 754 LM 755
+
Sbjct: 379 FL 380
Score = 60.1 bits (144), Expect = 1e-08
Identities = 46/155 (29%), Positives = 71/155 (45%), Gaps = 6/155 (3%)
Query: 601 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 660
L+ A+ + +++ L+ V T G T L AC GFVD V L ++
Sbjct: 265 LMAASSGGYLDIVKLLLLHDADVNSQSAT---GNTALTYACAGGFVDIVKVLLN-EGANI 320
Query: 661 NWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRA 720
+ G+T L+ AA AGH + LL++ G++ N F +AL A +G D +R
Sbjct: 321 EDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHS-NEFKESALTLACYKGHLDMVRF 379
Query: 721 LMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 755
L+ AGAD + + E A G V+ RL+
Sbjct: 380 LLEAGADQEHKTDEMHTALME-ACMDGHVEVARLL 413
Score = 54.3 bits (129), Expect = 6e-07
Identities = 42/131 (32%), Positives = 68/131 (51%), Gaps = 10/131 (7%)
Query: 601 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 660
L AAC +V L L+ RG ++EE + G T L+ A G + +VAL ++
Sbjct: 431 LTLAACGGHVELAALLIERGANLEEVND---EGYTPLMEAAREGH-EEMVALLLAQGANI 486
Query: 661 NWQDSEGN-TALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIR 719
N Q E TAL A G + + ++L+ G D+E + T LM+A+ +G + ++
Sbjct: 487 NAQTEETQETALTLACCGGFSEVADFLIK--AGADIELGCS---TPLMEASQEGHLELVK 541
Query: 720 ALMLAGADVHA 730
L+ +GA+VHA
Sbjct: 542 YLLASGANVHA 552
Score = 50.1 bits (118), Expect = 1e-05
Identities = 42/162 (25%), Positives = 68/162 (41%), Gaps = 34/162 (20%)
Query: 601 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 660
L+ AA A +V + R L+ G + ++ + L +ACY G +D V L E D
Sbjct: 331 LMEAASAGHVEVARVLLDHGAGINT--HSNEFKESALTLACYKGHLDMVRFLLEAG-ADQ 387
Query: 661 NWQDSEGNTALITAAQAGHAIITNYLLNYFP----------------------------- 691
+ E +TAL+ A GH + LL+
Sbjct: 388 EHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLI 447
Query: 692 --GLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHAR 731
G +LE N G+T LM+AA +G + + L+ GA+++A+
Sbjct: 448 ERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQ 489
>gi|46519147 ankyrin repeat and KH domain containing 1 isoform 1
[Homo sapiens]
Length = 2542
Score = 65.5 bits (158), Expect = 2e-10
Identities = 57/182 (31%), Positives = 80/182 (43%), Gaps = 6/182 (3%)
Query: 575 DEEEHGVESAESVPEGVPESVPETATLLRAAC-ANNVGLLRTLVRRGVSVEEAQETDRNG 633
D + + V V E E +LL AC A L + L+ +VE+ ++
Sbjct: 215 DGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVED--RGNKGD 272
Query: 634 RTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGL 693
T L+ A G++D +V L DVN Q + GNTAL A G I LLN G
Sbjct: 273 ITPLMAASSGGYLD-IVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLN--EGA 329
Query: 694 DLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVR 753
++E N G T LM+AA G + R L+ GA ++ S A Y G +D VR
Sbjct: 330 NIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVR 389
Query: 754 LM 755
+
Sbjct: 390 FL 391
Score = 60.1 bits (144), Expect = 1e-08
Identities = 46/155 (29%), Positives = 71/155 (45%), Gaps = 6/155 (3%)
Query: 601 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 660
L+ A+ + +++ L+ V T G T L AC GFVD V L ++
Sbjct: 276 LMAASSGGYLDIVKLLLLHDADVNSQSAT---GNTALTYACAGGFVDIVKVLLN-EGANI 331
Query: 661 NWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRA 720
+ G+T L+ AA AGH + LL++ G++ N F +AL A +G D +R
Sbjct: 332 EDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHS-NEFKESALTLACYKGHLDMVRF 390
Query: 721 LMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 755
L+ AGAD + + E A G V+ RL+
Sbjct: 391 LLEAGADQEHKTDEMHTALME-ACMDGHVEVARLL 424
Score = 55.5 bits (132), Expect = 3e-07
Identities = 43/155 (27%), Positives = 74/155 (47%), Gaps = 3/155 (1%)
Query: 601 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 660
L+ AA A +VG++ L+ +G +E +++R T L +AC G + VV L +
Sbjct: 1092 LILAATAGHVGVVEILLDKGGDIEA--QSERTKDTPLSLACSGGRQE-VVDLLLARGANK 1148
Query: 661 NWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRA 720
++ T L AA G+ I LLN ++ + G + LM AAM G ++
Sbjct: 1149 EHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKL 1208
Query: 721 LMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 755
L+ G+D++A+ + A + GR + V L+
Sbjct: 1209 LLDMGSDINAQIETNRNTALTLACFQGRAEVVSLL 1243
Score = 50.1 bits (118), Expect = 1e-05
Identities = 42/162 (25%), Positives = 68/162 (41%), Gaps = 34/162 (20%)
Query: 601 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 660
L+ AA A +V + R L+ G + ++ + L +ACY G +D V L E D
Sbjct: 342 LMEAASAGHVEVARVLLDHGAGINT--HSNEFKESALTLACYKGHLDMVRFLLEAG-ADQ 398
Query: 661 NWQDSEGNTALITAAQAGHAIITNYLLNYFP----------------------------- 691
+ E +TAL+ A GH + LL+
Sbjct: 399 EHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLI 458
Query: 692 --GLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHAR 731
G +LE N G+T LM+AA +G + + L+ GA+++A+
Sbjct: 459 ERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQ 500
Score = 48.5 bits (114), Expect = 3e-05
Identities = 42/138 (30%), Positives = 69/138 (50%), Gaps = 5/138 (3%)
Query: 594 SVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALA 653
+V + L AA V +++ L+ G + ++ + G + L++A +G V V L
Sbjct: 1152 NVSDYTPLSLAASGGYVNIIKILLNAGAEIN-SRTGSKLGISPLMLAAMNGHVPAVKLLL 1210
Query: 654 ECPHVDVNWQ-DSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQ 712
+ D+N Q ++ NTAL A G A + + LL+ ++E R G T LM+AA
Sbjct: 1211 DMGS-DINAQIETNRNTALTLACFQGRAEVVSLLLDR--KANVEHRAKTGLTPLMEAASG 1267
Query: 713 GRTDCIRALMLAGADVHA 730
G + R L+ GADV+A
Sbjct: 1268 GYAEVGRVLLDKGADVNA 1285
Score = 47.0 bits (110), Expect = 9e-05
Identities = 46/163 (28%), Positives = 69/163 (42%), Gaps = 10/163 (6%)
Query: 593 ESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVAL 652
E ETA L A C + L++ G +E T L+ A G ++ V L
Sbjct: 502 EETQETALTL-ACCGGFSEVADFLIKAGADIELGCSTP------LMEASQEGHLELVKYL 554
Query: 653 AECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQ 712
+V+ + G+TAL A + GH + + LL G DLE + G T LMKAA
Sbjct: 555 L-ASGANVHATTATGDTALTYACENGHTDVADVLLQ--AGADLEHESEGGRTPLMKAARA 611
Query: 713 GRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 755
G ++ L+ GA+V+ + A G + V L+
Sbjct: 612 GHLCTVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELL 654
Score = 46.2 bits (108), Expect = 2e-04
Identities = 32/97 (32%), Positives = 51/97 (52%), Gaps = 3/97 (3%)
Query: 593 ESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVAL 652
ES L++AA A ++ ++ L+ +G +V A T N T + +AC G + VV L
Sbjct: 597 ESEGGRTPLMKAARAGHLCTVQFLISKGANVNRA--TANNDHTVVSLACAGGHL-AVVEL 653
Query: 653 AECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNY 689
D + +G+T LI AA+ GH + +YLL+Y
Sbjct: 654 LLAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLLDY 690
Score = 44.3 bits (103), Expect = 6e-04
Identities = 31/101 (30%), Positives = 48/101 (47%), Gaps = 3/101 (2%)
Query: 656 PHVDVNWQ-DSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGR 714
P VD++ +S +TAL A GH + + L+ +E R+ GFT L+ AA G
Sbjct: 1043 PSVDIDAHTESNHDTALTLACAGGHEELVSVLIAR--DAKIEHRDKKGFTPLILAATAGH 1100
Query: 715 TDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 755
+ L+ G D+ A+ R +P A GR + V L+
Sbjct: 1101 VGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLL 1141
Score = 33.9 bits (76), Expect = 0.79
Identities = 32/109 (29%), Positives = 49/109 (44%), Gaps = 10/109 (9%)
Query: 591 VPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVV 650
VP S T+ AA + L+ RG ++ ++ G T L +A G D V
Sbjct: 1288 VPSSRDTALTI--AADKGHYKFCELLIHRGAHIDVR---NKKGNTPLWLASNGGHFDVVQ 1342
Query: 651 ALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYL---LNYFPGLDLE 696
L + DV+ D+ T L++A + GH + YL +N FP D+E
Sbjct: 1343 LLVQAG-ADVDAADNRKITPLMSAFRKGHVKVVQYLVKEVNQFPS-DIE 1389
Score = 33.1 bits (74), Expect = 1.3
Identities = 41/161 (25%), Positives = 69/161 (42%), Gaps = 13/161 (8%)
Query: 600 TLLRAACANN-VGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAEC-PH 657
T L AC+ ++ L+ RG + E +D T L +A G+V+ + L
Sbjct: 1124 TPLSLACSGGRQEVVDLLLARGANKEHRNVSDY---TPLSLAASGGYVNIIKILLNAGAE 1180
Query: 658 VDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE---RRNAFGFTALMKAAMQGR 714
++ G + L+ AA GH LL+ ++ + RN TAL A QGR
Sbjct: 1181 INSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRN----TALTLACFQGR 1236
Query: 715 TDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 755
+ + L+ A+V R + G++P A G + R++
Sbjct: 1237 AEVVSLLLDRKANVEHR-AKTGLTPLMEAASGGYAEVGRVL 1276
>gi|37620163 ANKHD1-EIF4EBP3 protein [Homo sapiens]
Length = 2617
Score = 65.5 bits (158), Expect = 2e-10
Identities = 57/182 (31%), Positives = 80/182 (43%), Gaps = 6/182 (3%)
Query: 575 DEEEHGVESAESVPEGVPESVPETATLLRAAC-ANNVGLLRTLVRRGVSVEEAQETDRNG 633
D + + V V E E +LL AC A L + L+ +VE+ ++
Sbjct: 215 DGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVED--RGNKGD 272
Query: 634 RTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGL 693
T L+ A G++D +V L DVN Q + GNTAL A G I LLN G
Sbjct: 273 ITPLMAASSGGYLD-IVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLN--EGA 329
Query: 694 DLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVR 753
++E N G T LM+AA G + R L+ GA ++ S A Y G +D VR
Sbjct: 330 NIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVR 389
Query: 754 LM 755
+
Sbjct: 390 FL 391
Score = 60.1 bits (144), Expect = 1e-08
Identities = 46/155 (29%), Positives = 71/155 (45%), Gaps = 6/155 (3%)
Query: 601 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 660
L+ A+ + +++ L+ V T G T L AC GFVD V L ++
Sbjct: 276 LMAASSGGYLDIVKLLLLHDADVNSQSAT---GNTALTYACAGGFVDIVKVLLN-EGANI 331
Query: 661 NWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRA 720
+ G+T L+ AA AGH + LL++ G++ N F +AL A +G D +R
Sbjct: 332 EDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHS-NEFKESALTLACYKGHLDMVRF 390
Query: 721 LMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 755
L+ AGAD + + E A G V+ RL+
Sbjct: 391 LLEAGADQEHKTDEMHTALME-ACMDGHVEVARLL 424
Score = 55.5 bits (132), Expect = 3e-07
Identities = 43/155 (27%), Positives = 74/155 (47%), Gaps = 3/155 (1%)
Query: 601 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 660
L+ AA A +VG++ L+ +G +E +++R T L +AC G + VV L +
Sbjct: 1092 LILAATAGHVGVVEILLDKGGDIEA--QSERTKDTPLSLACSGGRQE-VVDLLLARGANK 1148
Query: 661 NWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRA 720
++ T L AA G+ I LLN ++ + G + LM AAM G ++
Sbjct: 1149 EHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKL 1208
Query: 721 LMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 755
L+ G+D++A+ + A + GR + V L+
Sbjct: 1209 LLDMGSDINAQIETNRNTALTLACFQGRAEVVSLL 1243
Score = 50.1 bits (118), Expect = 1e-05
Identities = 42/162 (25%), Positives = 68/162 (41%), Gaps = 34/162 (20%)
Query: 601 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 660
L+ AA A +V + R L+ G + ++ + L +ACY G +D V L E D
Sbjct: 342 LMEAASAGHVEVARVLLDHGAGINT--HSNEFKESALTLACYKGHLDMVRFLLEAG-ADQ 398
Query: 661 NWQDSEGNTALITAAQAGHAIITNYLLNYFP----------------------------- 691
+ E +TAL+ A GH + LL+
Sbjct: 399 EHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLI 458
Query: 692 --GLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHAR 731
G +LE N G+T LM+AA +G + + L+ GA+++A+
Sbjct: 459 ERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQ 500
Score = 48.5 bits (114), Expect = 3e-05
Identities = 42/138 (30%), Positives = 69/138 (50%), Gaps = 5/138 (3%)
Query: 594 SVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALA 653
+V + L AA V +++ L+ G + ++ + G + L++A +G V V L
Sbjct: 1152 NVSDYTPLSLAASGGYVNIIKILLNAGAEIN-SRTGSKLGISPLMLAAMNGHVPAVKLLL 1210
Query: 654 ECPHVDVNWQ-DSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQ 712
+ D+N Q ++ NTAL A G A + + LL+ ++E R G T LM+AA
Sbjct: 1211 DMGS-DINAQIETNRNTALTLACFQGRAEVVSLLLDR--KANVEHRAKTGLTPLMEAASG 1267
Query: 713 GRTDCIRALMLAGADVHA 730
G + R L+ GADV+A
Sbjct: 1268 GYAEVGRVLLDKGADVNA 1285
Score = 47.0 bits (110), Expect = 9e-05
Identities = 46/163 (28%), Positives = 69/163 (42%), Gaps = 10/163 (6%)
Query: 593 ESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVAL 652
E ETA L A C + L++ G +E T L+ A G ++ V L
Sbjct: 502 EETQETALTL-ACCGGFSEVADFLIKAGADIELGCSTP------LMEASQEGHLELVKYL 554
Query: 653 AECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQ 712
+V+ + G+TAL A + GH + + LL G DLE + G T LMKAA
Sbjct: 555 L-ASGANVHATTATGDTALTYACENGHTDVADVLLQ--AGADLEHESEGGRTPLMKAARA 611
Query: 713 GRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 755
G ++ L+ GA+V+ + A G + V L+
Sbjct: 612 GHLCTVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELL 654
Score = 46.2 bits (108), Expect = 2e-04
Identities = 32/97 (32%), Positives = 51/97 (52%), Gaps = 3/97 (3%)
Query: 593 ESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVAL 652
ES L++AA A ++ ++ L+ +G +V A T N T + +AC G + VV L
Sbjct: 597 ESEGGRTPLMKAARAGHLCTVQFLISKGANVNRA--TANNDHTVVSLACAGGHL-AVVEL 653
Query: 653 AECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNY 689
D + +G+T LI AA+ GH + +YLL+Y
Sbjct: 654 LLAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLLDY 690
Score = 44.3 bits (103), Expect = 6e-04
Identities = 31/101 (30%), Positives = 48/101 (47%), Gaps = 3/101 (2%)
Query: 656 PHVDVNWQ-DSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGR 714
P VD++ +S +TAL A GH + + L+ +E R+ GFT L+ AA G
Sbjct: 1043 PSVDIDAHTESNHDTALTLACAGGHEELVSVLIAR--DAKIEHRDKKGFTPLILAATAGH 1100
Query: 715 TDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 755
+ L+ G D+ A+ R +P A GR + V L+
Sbjct: 1101 VGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLL 1141
Score = 33.9 bits (76), Expect = 0.79
Identities = 32/109 (29%), Positives = 49/109 (44%), Gaps = 10/109 (9%)
Query: 591 VPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVV 650
VP S T+ AA + L+ RG ++ ++ G T L +A G D V
Sbjct: 1288 VPSSRDTALTI--AADKGHYKFCELLIHRGAHIDVR---NKKGNTPLWLASNGGHFDVVQ 1342
Query: 651 ALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYL---LNYFPGLDLE 696
L + DV+ D+ T L++A + GH + YL +N FP D+E
Sbjct: 1343 LLVQAG-ADVDAADNRKITPLMSAFRKGHVKVVQYLVKEVNQFPS-DIE 1389
Score = 33.1 bits (74), Expect = 1.3
Identities = 41/161 (25%), Positives = 69/161 (42%), Gaps = 13/161 (8%)
Query: 600 TLLRAACANN-VGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAEC-PH 657
T L AC+ ++ L+ RG + E +D T L +A G+V+ + L
Sbjct: 1124 TPLSLACSGGRQEVVDLLLARGANKEHRNVSDY---TPLSLAASGGYVNIIKILLNAGAE 1180
Query: 658 VDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE---RRNAFGFTALMKAAMQGR 714
++ G + L+ AA GH LL+ ++ + RN TAL A QGR
Sbjct: 1181 INSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRN----TALTLACFQGR 1236
Query: 715 TDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 755
+ + L+ A+V R + G++P A G + R++
Sbjct: 1237 AEVVSLLLDRKANVEHR-AKTGLTPLMEAASGGYAEVGRVL 1276
>gi|70995267 ankyrin repeat domain 29 [Homo sapiens]
Length = 301
Score = 65.5 bits (158), Expect = 2e-10
Identities = 50/152 (32%), Positives = 73/152 (48%), Gaps = 6/152 (3%)
Query: 604 AACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQ 663
AA N+ LL+ L+ G + + D +G T L+VA Y G +D V L D+N Q
Sbjct: 19 AARRGNLALLKLLLNSGRVDVDCR--DSHGTTLLMVAAYAGHIDCVRELV-LQGADINLQ 75
Query: 664 DSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALML 723
G TAL AAQ GH + +L + G E R G TAL+ A+ G + L+
Sbjct: 76 RESGTTALFFAAQQGHNDVVRFLFGF--GASTEFRTKDGGTALLAASQYGHMQVVETLLK 133
Query: 724 AGADVHARDPRRGMSPQEWATYTGRVDAVRLM 755
GA++H + G + A G +D +RL+
Sbjct: 134 HGANIHDQ-LYDGATALFLAAQGGYLDVIRLL 164
Score = 62.0 bits (149), Expect = 3e-09
Identities = 52/159 (32%), Positives = 78/159 (49%), Gaps = 9/159 (5%)
Query: 598 TATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPH 657
T L+ AA A ++ +R LV +G + +E+ G T L A G D V L
Sbjct: 47 TTLLMVAAYAGHIDCVRELVLQGADINLQRES---GTTALFFAAQQGHNDVVRFLFGFG- 102
Query: 658 VDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDC 717
++ +G TAL+ A+Q GH + LL + G ++ + G TAL AA G D
Sbjct: 103 ASTEFRTKDGGTALLAASQYGHMQVVETLLKH--GANIHDQLYDGATALFLAAQGGYLDV 160
Query: 718 IRALMLAGADVHARDPRR-GMSPQEWATYTGRVDAVRLM 755
IR L+ +GA V+ PR+ G +P A+ G + VR+M
Sbjct: 161 IRLLLASGAKVN--QPRQDGTAPLWIASQMGHSEVVRVM 197
Score = 51.2 bits (121), Expect = 5e-06
Identities = 42/155 (27%), Positives = 72/155 (46%), Gaps = 8/155 (5%)
Query: 601 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 660
LL A+ ++ ++ TL++ G ++ + +G T L +A G++D V+ L V
Sbjct: 116 LLAASQYGHMQVVETLLKHGANIHDQLY---DGATALFLAAQGGYLD-VIRLLLASGAKV 171
Query: 661 NWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRA 720
N +G L A+Q GH+ + +L G D + G TAL+KAA +G D I+
Sbjct: 172 NQPRQDGTAPLWIASQMGHSEVVRVML--LRGADRDAARNDGTTALLKAANKGYNDVIKE 229
Query: 721 LMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 755
L+ + + G S A +G + V L+
Sbjct: 230 LLKFSPTLGIL--KNGTSALHAAVLSGNIKTVALL 262
Score = 45.8 bits (107), Expect = 2e-04
Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 2/86 (2%)
Query: 670 ALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVH 729
A AA+ G+ + LLN +D++ R++ G T LM AA G DC+R L+L GAD++
Sbjct: 15 AAFWAARRGNLALLKLLLNS-GRVDVDCRDSHGTTLLMVAAYAGHIDCVRELVLQGADIN 73
Query: 730 ARDPRRGMSPQEWATYTGRVDAVRLM 755
+ G + +A G D VR +
Sbjct: 74 LQ-RESGTTALFFAAQQGHNDVVRFL 98
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 64.7 bits (156), Expect = 4e-10
Identities = 129/476 (27%), Positives = 159/476 (33%), Gaps = 101/476 (21%)
Query: 77 RNRCSRAPHPPGPC---RCRVGGRQQALWLLLETLEDQATRTAGRAS-ALAQRHVGLKPG 132
R+ P P P R R G + L + + R S + A H +P
Sbjct: 153 RDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPS 212
Query: 133 PQRLRQPSCVHLGAARASHRLAAGGHAVKIGGKKGRKEARGTQGWWPPQSLTCDGRERTS 192
P R+PS GG R +R P S S
Sbjct: 213 PAARRRPSA---------------------GGGLQRPASRSLSSSATPLSSPA-----RS 246
Query: 193 APLRRDLPPRLAHDASYPEVKGSLWQILTRPP---PPRPSPAPGLTGRGQGRARGAVGLD 249
P R P AH S P+ KG Q L RPP PPR AP L G +
Sbjct: 247 GPSARGTPRAPAHP-SQPKPKGL--QAL-RPPQVTPPRKDAAPAL---------GPLSSS 293
Query: 250 CGCRPRPCSFGQPDVGSAPSRSLRGCSLRFRNTPPPIPGSDQPSSHGRPRFRETGDSEDC 309
P P + P SAP SL+ +PP P S +S G P + T
Sbjct: 294 PLATPSPSA---PPSPSAPP------SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPS 344
Query: 310 PPFR--AGTPPQQPTA----PSSEWPGPQRSPGTGPRWTAPLPRPAPLPAKRPGDSPASK 363
PP A PPQ P A P P P SP P T P P+ A +P S
Sbjct: 345 PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLAT-PSPQAPNALAVHLLQAPFSP 403
Query: 364 RPRPGGVSPEARDPPKGENPLCSSEAAGETGPTQVRGPDALGGGRLQGKGREGKAPGEGV 423
P P +P + P P+ S T P+Q P +L LQ +P +
Sbjct: 404 PPSPPVQAPFS---PPASPPVSPSA----TPPSQA--PPSLAAPPLQVPPSPPASPP--M 452
Query: 424 SPRPAPPRLGKPPRSRPPQGLAQPPETFFFERSRLVPVSAELERAGHGFSGDAEARSGDL 483
SP PP PP + PP LA+PP + P L F G A
Sbjct: 453 SPSATPPPQAPPPLAAPPLQLAKPPPQ--APPALATPPLQALPSPPASFPGQA------- 503
Query: 484 GARPASRS-SLPSAP--APPAQQPQAARHGAAGRDQGRRAAGAQLHDPTTQPSPPT 536
P S S SLP +P PP Q P A L P + P+ PT
Sbjct: 504 ---PFSPSASLPMSPLATPPPQAPPV-------------LAAPLLQVPPSPPASPT 543
Score = 59.7 bits (143), Expect = 1e-08
Identities = 101/401 (25%), Positives = 130/401 (32%), Gaps = 86/401 (21%)
Query: 114 RTAGRASALAQRHVGLKPGPQRLRQPSCVHLGAARASHRLAAGGHAVKIGGKKGRKEARG 173
R +A A A+ PG R P L G A +G K + A G
Sbjct: 5 RDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGG 64
Query: 174 TQGWWPPQSLTCDGRERTSAPLRRDLPPRLAHDASYPEVKGSLWQILTRPPPPRPSPAPG 233
G P+S G RTS PP P K + P P SP
Sbjct: 65 IGGATIPESAPRAGPTRTSR------PPASGRGERAPPAKNT-------SPGPVSSP--- 108
Query: 234 LTGRGQGRAR----GAVGLDCGCRPRPCSFGQPDVGSAPSRSLRGCSLRFRNTPPPIPGS 289
GR G R G GL + + AP RS R R+T P PG+
Sbjct: 109 --GRASGTTRPGPLGQKGLRISAEE---TVARGKATEAPKRSALSAGAR-RDTSGPTPGT 162
Query: 290 DQPSSHGRPRFRETGDSEDCPPFRAGTPPQQPTA-PSSEWPGPQRSPGTGPRWTAPLPRP 348
P+ R R T G P P+A P GP++S + + P P
Sbjct: 163 PSPAMARRSRAAGT---------EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSP 213
Query: 349 APLPAKRPGDSPASKRPRPGG--VSPEARDPPKGENPLCSSEAAGETGPTQVRGPDALGG 406
A A +RP GG P +R PL S + GP A G
Sbjct: 214 A-----------ARRRPSAGGGLQRPASRSLSSSATPLSSPARS---------GPSARGT 253
Query: 407 GRLQGKGREGKAPGEGVSPRPAPPRLGKPPRSRPPQGLAQPPETFFFERSRLVPVSAELE 466
R AP P+P + +PP+ PP+ A P L P+S
Sbjct: 254 PR---------APAHPSQPKPKGLQALRPPQVTPPRKDAAP---------ALGPLS---- 291
Query: 467 RAGHGFSGDAEARSGDLGARPASRSSLPSAPAPPAQQPQAA 507
S S P++ SL + P+PPA P A
Sbjct: 292 ------SSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQA 326
Score = 47.4 bits (111), Expect = 7e-05
Identities = 79/294 (26%), Positives = 105/294 (35%), Gaps = 60/294 (20%)
Query: 282 TPPPIPGSDQPSSHGRPR-FRETGDSEDCPPFRAGTPPQQPTAPSSEWPG----PQRSPG 336
TP P PGS +P P R G AG ++P A + G P+ +P
Sbjct: 26 TPRP-PGSPRPPPPVTPAALRVLG--------AAGAVGRKPLAERAGGIGGATIPESAPR 76
Query: 337 TGPRWTA------------PLPRPAPLPAKRPGDSPASKRPRPGG-----VSPE------ 373
GP T+ P +P P PG + + RP P G +S E
Sbjct: 77 AGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARG 136
Query: 374 -ARDPPKGENPLCSSEAAGETGPTQVRGPDALGGGRLQGKGREGKAPGEGVS-PRPAPPR 431
A + PK + L + +GPT G R +A G V PRPAP
Sbjct: 137 KATEAPK-RSALSAGARRDTSGPTP--------GTPSPAMARRSRAAGTEVGLPRPAPSA 187
Query: 432 LGKPPRSRPPQGLAQPPETFFFERS----RLVPVSAELER-AGHGFSGDAEARSGDLGAR 486
+PP P + ++ E E S R L+R A S A S +
Sbjct: 188 RPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG 247
Query: 487 PASRSSLPSAPAPPAQQP----QAAR--HGAAGRDQGRRAAGAQLHDPTTQPSP 534
P++R + P APA P+Q QA R R A G P PSP
Sbjct: 248 PSARGT-PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 300
Score = 42.7 bits (99), Expect = 0.002
Identities = 63/227 (27%), Positives = 87/227 (38%), Gaps = 31/227 (13%)
Query: 349 APLPAKRPGDSPASKRPRPGGVSPEARDPPKGENPLCSSEAAGETGPTQVRGPDALGGGR 408
A PA R +P PRP G SP PP L AAG G R P A G
Sbjct: 14 ARTPAAR---APGLLTPRPPG-SPRP-PPPVTPAALRVLGAAGAVG----RKPLAERAGG 64
Query: 409 LQGKGREGKAPGEGVSPRPAPPRLGKPPRSRPPQGLAQPPETFFFERS----------RL 458
+ G AP G + PP G+ R+ P + + P + S +
Sbjct: 65 IGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKG 124
Query: 459 VPVSAELERAGHGFSGDAEARSG-DLGARPASRSSLPSAPAPPAQQPQAARHGAAGRDQG 517
+ +SAE E G + +A RS GAR + P P+P A R AAG +
Sbjct: 125 LRISAE-ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSP----AMARRSRAAGTE-- 177
Query: 518 RRAAGAQLHDPTTQPSPPT-GAQQVEEDPADYEEFEDILESARHPQA 563
G P+ +P PPT G ++ +++ E + R P A
Sbjct: 178 ---VGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA 221
Score = 30.8 bits (68), Expect = 6.7
Identities = 50/207 (24%), Positives = 65/207 (31%), Gaps = 45/207 (21%)
Query: 282 TPPPIPGSDQPSSHGRPRFRETGDSEDCPPFRAGTPPQQPTAPSSEWPG-----PQRS-- 334
TPPP P P + PP A P Q +P + +PG P S
Sbjct: 457 TPPP----QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 512
Query: 335 --------PGTGPRWTAPLPRPAPLPAKRPGDSPASKRPRPG------------GVSPEA 374
P P APL + P P P + P PG ++P
Sbjct: 513 MSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP 572
Query: 375 RDPP--KGENPLCSSEAAGETG-----PTQVRGPDALGGGRLQGKGREGKAPGEGVSPRP 427
PP + L + AG + P ++RG D+ G G E + P
Sbjct: 573 PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS---GPEGGAAASPPPDAELAACHP 629
Query: 428 APPRLGKPP----RSRPPQGLAQPPET 450
A G P R P L PP T
Sbjct: 630 AAWSRGPAPPLAFRGAPGAPLPWPPAT 656
Score = 30.4 bits (67), Expect = 8.7
Identities = 50/190 (26%), Positives = 65/190 (34%), Gaps = 30/190 (15%)
Query: 179 PPQSLTCDGRERTSAPLRRDLPPRLAHDASYPEVKGSLWQILTRPPPPRPSPAPGLTGRG 238
PP S T R PP D S + +L PPPP SP+ L+G
Sbjct: 538 PPASPTLQAPRR---------PPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPD 588
Query: 239 -QGRARGAV-------GLDCGCRPRPCSFGQPDVGSA---PSRSLRGCS--LRFRNTP-- 283
G + A G D G + PD A P+ RG + L FR P
Sbjct: 589 LAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGA 648
Query: 284 --PPIPGSDQPSSHGRPRFRETGDSEDCPPFRAGTPPQQPTAPSSEWPGPQRSPGTGPRW 341
P P + S+ G ET E P P PS G + + G G
Sbjct: 649 PLPWPPATGPGSADGLCTIYETEGPESATPAPGALDP----GPSPGTSGGKAAAGAGAGA 704
Query: 342 TAPLPRPAPL 351
++ P+ A L
Sbjct: 705 SSRSPKQARL 714
>gi|239744358 PREDICTED: hypothetical protein XP_002343105 [Homo
sapiens]
Length = 767
Score = 63.9 bits (154), Expect = 7e-10
Identities = 31/46 (67%), Positives = 36/46 (78%), Gaps = 1/46 (2%)
Query: 961 DSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAEAQKERRTAPWKKRT 1006
D+ HL+ PKW YK A EEK +AEEAEKKRQA+ Q E+R PWKKRT
Sbjct: 202 DTRHLRTPKWPYKVATEEKPEAEEAEKKRQAKVQ-EKRLPPWKKRT 246
Score = 62.4 bits (150), Expect = 2e-09
Identities = 36/68 (52%), Positives = 41/68 (60%), Gaps = 6/68 (8%)
Query: 723 LAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAA 782
LAGA +HAR P G + + VRL QRLLERPC E +KY+ ELPP E A
Sbjct: 93 LAGAVIHARAPAVGCRQRSGHLH------VRLKQRLLERPCQEPLGKKYQLELPPLYERA 146
Query: 783 RKPAGSKN 790
RKP GSKN
Sbjct: 147 RKPEGSKN 154
Score = 55.1 bits (131), Expect = 3e-07
Identities = 30/61 (49%), Positives = 36/61 (59%), Gaps = 1/61 (1%)
Query: 529 TTQPSPPTGAQQVEEDPADYEEFEDILESARHPQASHSDDSFYPFEDEEEHGVESAESVP 588
T P P QV+ED ADY+EF+D S D SFYPF++EEEHGV+ ESV
Sbjct: 2 TPPPPSPLLGTQVKEDRADYKEFQDF-SSLPDTHNIAWDHSFYPFQEEEEHGVKGVESVL 60
Query: 589 E 589
E
Sbjct: 61 E 61
>gi|169208169 PREDICTED: similar to kinase D-interacting substrate
220 [Homo sapiens]
Length = 380
Score = 63.5 bits (153), Expect = 9e-10
Identities = 86/317 (27%), Positives = 119/317 (37%), Gaps = 31/317 (9%)
Query: 613 LRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALI 672
+R L+ +G +V D GRT L +AC G +D V L + D DS GN+ ++
Sbjct: 67 VRLLLEQGAAVNLR---DERGRTALSLACERGHLDAVQLLVQFSG-DPEAADSAGNSPVM 122
Query: 673 TAAQAGHAIITNYLLNYFP--GLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHA 730
AA GH + +L+ F GL L+R N G TAL AA +G C++AL A
Sbjct: 123 WAAACGHGAVLEFLVRSFRRLGLRLDRTNRAGLTALQLAAARGHGTCVQALTGPWGRAAA 182
Query: 731 RDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARKPAGSKN 790
RG + + GR + RP P + RP L AA G
Sbjct: 183 AAAARGSNSD---SPPGRPAPAASPEH--RRPSPRRL---PRPLLARFARAAGGHGGEAG 234
Query: 791 CLQRLTDCVLSVLTPRSVRGPEDGGVLDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKR 850
+ + + + R PE G + + T + + P SP S G
Sbjct: 235 SAGKNSGRHRAQGSER----PELGRSMSLALGAVTEEEAARLRAGALMALPNSPQSSGTG 290
Query: 851 RLAVQEILAA---RAARGPQAQEEDEVGGAGQRGRTGQEDADSREGSPRAGLPPALGSRG 907
R QE+L A+ P GG G GR G R S +P +G
Sbjct: 291 RWRSQEVLEGAPPTLAQAPIGLSPHPEGGPGS-GRLG-----LRRRSTAPDIPSLVGE-- 342
Query: 908 PAAPAPRKASLLPLQRL 924
AP P L L
Sbjct: 343 --APGPESGPELEANAL 357
Score = 39.3 bits (90), Expect = 0.019
Identities = 56/187 (29%), Positives = 74/187 (39%), Gaps = 31/187 (16%)
Query: 187 GRERTSAPLR---RDLPPRLAHDASYPEVKGSLWQILTRPPPPRPSPAPGLTGRGQGRAR 243
GR +A R D PP A+ PE + + L RP R + A G G G
Sbjct: 178 GRAAAAAAARGSNSDSPPGRPAPAASPEHRRPSPRRLPRPLLARFARAAG----GHGGEA 233
Query: 244 GAVGLDCGCRPRPCSFGQPDVGSAPSRSLRGCS----LRFR-NTPPPIPGSDQPSSHGRP 298
G+ G + G R R +P++G + S +L + R R +P S Q S GR
Sbjct: 234 GSAGKNSG-RHRAQGSERPELGRSMSLALGAVTEEEAARLRAGALMALPNSPQSSGTGRW 292
Query: 299 RFRETGDSEDCPPFRAGTPPQQPTAPSSEWPGPQRSPGTG-----PRWTAP----LPRPA 349
R +E + G PP AP P P+ PG+G R TAP L A
Sbjct: 293 RSQEVLE---------GAPPTLAQAPIGLSPHPEGGPGSGRLGLRRRSTAPDIPSLVGEA 343
Query: 350 PLPAKRP 356
P P P
Sbjct: 344 PGPESGP 350
>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
Length = 983
Score = 63.2 bits (152), Expect = 1e-09
Identities = 40/108 (37%), Positives = 60/108 (55%), Gaps = 5/108 (4%)
Query: 626 AQETDRNGRTGLIVACYHGFVDTVVALAECPHVD-VNWQDSEGNTALITAAQAGHAIITN 684
A+ D +G+T L A G + V L C H +N +D +GN L+ A Q GH+ I +
Sbjct: 115 AESVDSSGKTALHYAAAQGCLQAVQIL--CEHKSPINLKDLDGNIPLLLAVQNGHSEICH 172
Query: 685 YLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARD 732
+LL++ G D+ RN G TALM A G ++ + AL+ GAD++ D
Sbjct: 173 FLLDH--GADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVD 218
Score = 43.5 bits (101), Expect = 0.001
Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 3/119 (2%)
Query: 637 LIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE 696
L+ A +G + V +L DSEG TA AA GH ++ + G+D+
Sbjct: 26 LLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITH--GVDVT 83
Query: 697 RRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 755
++ G +AL AA +CIR L+ + + D G + +A G + AV+++
Sbjct: 84 AQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVD-SSGKTALHYAAAQGCLQAVQIL 141
Score = 36.6 bits (83), Expect = 0.12
Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 12/129 (9%)
Query: 665 SEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLA 724
++ + L+ A + G A LL G + ++ G TA AA +G +C+R ++
Sbjct: 20 NKNDDRLLQAVENGDAEKVASLLGK-KGASATKHDSEGKTAFHLAAAKGHVECLRVMITH 78
Query: 725 GADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARK 784
G DV A+D G S A + +R +LL+ CP + + + A
Sbjct: 79 GVDVTAQD-TTGHSALHLAAKNSHHECIR---KLLQSKCPAE-------SVDSSGKTALH 127
Query: 785 PAGSKNCLQ 793
A ++ CLQ
Sbjct: 128 YAAAQGCLQ 136
>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
Length = 972
Score = 63.2 bits (152), Expect = 1e-09
Identities = 40/108 (37%), Positives = 60/108 (55%), Gaps = 5/108 (4%)
Query: 626 AQETDRNGRTGLIVACYHGFVDTVVALAECPHVD-VNWQDSEGNTALITAAQAGHAIITN 684
A+ D +G+T L A G + V L C H +N +D +GN L+ A Q GH+ I +
Sbjct: 104 AESVDSSGKTALHYAAAQGCLQAVQIL--CEHKSPINLKDLDGNIPLLLAVQNGHSEICH 161
Query: 685 YLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARD 732
+LL++ G D+ RN G TALM A G ++ + AL+ GAD++ D
Sbjct: 162 FLLDH--GADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVD 207
Score = 43.5 bits (101), Expect = 0.001
Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 3/119 (2%)
Query: 637 LIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE 696
L+ A +G + V +L DSEG TA AA GH ++ + G+D+
Sbjct: 15 LLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITH--GVDVT 72
Query: 697 RRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 755
++ G +AL AA +CIR L+ + + D G + +A G + AV+++
Sbjct: 73 AQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVD-SSGKTALHYAAAQGCLQAVQIL 130
Score = 36.6 bits (83), Expect = 0.12
Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 12/129 (9%)
Query: 665 SEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLA 724
++ + L+ A + G A LL G + ++ G TA AA +G +C+R ++
Sbjct: 9 NKNDDRLLQAVENGDAEKVASLLGK-KGASATKHDSEGKTAFHLAAAKGHVECLRVMITH 67
Query: 725 GADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARK 784
G DV A+D G S A + +R +LL+ CP + + + A
Sbjct: 68 GVDVTAQD-TTGHSALHLAAKNSHHECIR---KLLQSKCPAE-------SVDSSGKTALH 116
Query: 785 PAGSKNCLQ 793
A ++ CLQ
Sbjct: 117 YAAAQGCLQ 125
>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
Length = 951
Score = 63.2 bits (152), Expect = 1e-09
Identities = 40/108 (37%), Positives = 60/108 (55%), Gaps = 5/108 (4%)
Query: 626 AQETDRNGRTGLIVACYHGFVDTVVALAECPHVD-VNWQDSEGNTALITAAQAGHAIITN 684
A+ D +G+T L A G + V L C H +N +D +GN L+ A Q GH+ I +
Sbjct: 112 AESVDSSGKTALHYAAAQGCLQAVQIL--CEHKSPINLKDLDGNIPLLLAVQNGHSEICH 169
Query: 685 YLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARD 732
+LL++ G D+ RN G TALM A G ++ + AL+ GAD++ D
Sbjct: 170 FLLDH--GADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVD 215
Score = 43.5 bits (101), Expect = 0.001
Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 3/119 (2%)
Query: 637 LIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE 696
L+ A +G + V +L DSEG TA AA GH ++ + G+D+
Sbjct: 23 LLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITH--GVDVT 80
Query: 697 RRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 755
++ G +AL AA +CIR L+ + + D G + +A G + AV+++
Sbjct: 81 AQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVD-SSGKTALHYAAAQGCLQAVQIL 138
Score = 36.6 bits (83), Expect = 0.12
Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 12/129 (9%)
Query: 665 SEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLA 724
++ + L+ A + G A LL G + ++ G TA AA +G +C+R ++
Sbjct: 17 NKNDDRLLQAVENGDAEKVASLLGK-KGASATKHDSEGKTAFHLAAAKGHVECLRVMITH 75
Query: 725 GADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARK 784
G DV A+D G S A + +R +LL+ CP + + + A
Sbjct: 76 GVDVTAQD-TTGHSALHLAAKNSHHECIR---KLLQSKCPAE-------SVDSSGKTALH 124
Query: 785 PAGSKNCLQ 793
A ++ CLQ
Sbjct: 125 YAAAQGCLQ 133
>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 63.2 bits (152), Expect = 1e-09
Identities = 40/108 (37%), Positives = 60/108 (55%), Gaps = 5/108 (4%)
Query: 626 AQETDRNGRTGLIVACYHGFVDTVVALAECPHVD-VNWQDSEGNTALITAAQAGHAIITN 684
A+ D +G+T L A G + V L C H +N +D +GN L+ A Q GH+ I +
Sbjct: 112 AESVDSSGKTALHYAAAQGCLQAVQIL--CEHKSPINLKDLDGNIPLLLAVQNGHSEICH 169
Query: 685 YLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARD 732
+LL++ G D+ RN G TALM A G ++ + AL+ GAD++ D
Sbjct: 170 FLLDH--GADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVD 215
Score = 43.5 bits (101), Expect = 0.001
Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 3/119 (2%)
Query: 637 LIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE 696
L+ A +G + V +L DSEG TA AA GH ++ + G+D+
Sbjct: 23 LLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITH--GVDVT 80
Query: 697 RRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 755
++ G +AL AA +CIR L+ + + D G + +A G + AV+++
Sbjct: 81 AQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVD-SSGKTALHYAAAQGCLQAVQIL 138
Score = 36.6 bits (83), Expect = 0.12
Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 12/129 (9%)
Query: 665 SEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLA 724
++ + L+ A + G A LL G + ++ G TA AA +G +C+R ++
Sbjct: 17 NKNDDRLLQAVENGDAEKVASLLGK-KGASATKHDSEGKTAFHLAAAKGHVECLRVMITH 75
Query: 725 GADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARK 784
G DV A+D G S A + +R +LL+ CP + + + A
Sbjct: 76 GVDVTAQD-TTGHSALHLAAKNSHHECIR---KLLQSKCPAE-------SVDSSGKTALH 124
Query: 785 PAGSKNCLQ 793
A ++ CLQ
Sbjct: 125 YAAAQGCLQ 133
>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 63.2 bits (152), Expect = 1e-09
Identities = 40/108 (37%), Positives = 60/108 (55%), Gaps = 5/108 (4%)
Query: 626 AQETDRNGRTGLIVACYHGFVDTVVALAECPHVD-VNWQDSEGNTALITAAQAGHAIITN 684
A+ D +G+T L A G + V L C H +N +D +GN L+ A Q GH+ I +
Sbjct: 112 AESVDSSGKTALHYAAAQGCLQAVQIL--CEHKSPINLKDLDGNIPLLLAVQNGHSEICH 169
Query: 685 YLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARD 732
+LL++ G D+ RN G TALM A G ++ + AL+ GAD++ D
Sbjct: 170 FLLDH--GADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVD 215
Score = 43.5 bits (101), Expect = 0.001
Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 3/119 (2%)
Query: 637 LIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE 696
L+ A +G + V +L DSEG TA AA GH ++ + G+D+
Sbjct: 23 LLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITH--GVDVT 80
Query: 697 RRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 755
++ G +AL AA +CIR L+ + + D G + +A G + AV+++
Sbjct: 81 AQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVD-SSGKTALHYAAAQGCLQAVQIL 138
Score = 36.6 bits (83), Expect = 0.12
Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 12/129 (9%)
Query: 665 SEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLA 724
++ + L+ A + G A LL G + ++ G TA AA +G +C+R ++
Sbjct: 17 NKNDDRLLQAVENGDAEKVASLLGK-KGASATKHDSEGKTAFHLAAAKGHVECLRVMITH 75
Query: 725 GADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARK 784
G DV A+D G S A + +R +LL+ CP + + + A
Sbjct: 76 GVDVTAQD-TTGHSALHLAAKNSHHECIR---KLLQSKCPAE-------SVDSSGKTALH 124
Query: 785 PAGSKNCLQ 793
A ++ CLQ
Sbjct: 125 YAAAQGCLQ 133
>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 63.2 bits (152), Expect = 1e-09
Identities = 40/108 (37%), Positives = 60/108 (55%), Gaps = 5/108 (4%)
Query: 626 AQETDRNGRTGLIVACYHGFVDTVVALAECPHVD-VNWQDSEGNTALITAAQAGHAIITN 684
A+ D +G+T L A G + V L C H +N +D +GN L+ A Q GH+ I +
Sbjct: 112 AESVDSSGKTALHYAAAQGCLQAVQIL--CEHKSPINLKDLDGNIPLLLAVQNGHSEICH 169
Query: 685 YLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARD 732
+LL++ G D+ RN G TALM A G ++ + AL+ GAD++ D
Sbjct: 170 FLLDH--GADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVD 215
Score = 43.5 bits (101), Expect = 0.001
Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 3/119 (2%)
Query: 637 LIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE 696
L+ A +G + V +L DSEG TA AA GH ++ + G+D+
Sbjct: 23 LLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITH--GVDVT 80
Query: 697 RRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 755
++ G +AL AA +CIR L+ + + D G + +A G + AV+++
Sbjct: 81 AQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVD-SSGKTALHYAAAQGCLQAVQIL 138
Score = 36.6 bits (83), Expect = 0.12
Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 12/129 (9%)
Query: 665 SEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLA 724
++ + L+ A + G A LL G + ++ G TA AA +G +C+R ++
Sbjct: 17 NKNDDRLLQAVENGDAEKVASLLGK-KGASATKHDSEGKTAFHLAAAKGHVECLRVMITH 75
Query: 725 GADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARK 784
G DV A+D G S A + +R +LL+ CP + + + A
Sbjct: 76 GVDVTAQD-TTGHSALHLAAKNSHHECIR---KLLQSKCPAE-------SVDSSGKTALH 124
Query: 785 PAGSKNCLQ 793
A ++ CLQ
Sbjct: 125 YAAAQGCLQ 133
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.133 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,504,159
Number of Sequences: 37866
Number of extensions: 3622944
Number of successful extensions: 32976
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 281
Number of HSP's successfully gapped in prelim test: 1986
Number of HSP's that attempted gapping in prelim test: 19109
Number of HSP's gapped (non-prelim): 11520
length of query: 1006
length of database: 18,247,518
effective HSP length: 112
effective length of query: 894
effective length of database: 14,006,526
effective search space: 12521834244
effective search space used: 12521834244
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.