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Search of human proteins with 193220941
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|193220941 hypothetical protein LOC400581 [Homo sapiens]
(118 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|193220941 hypothetical protein LOC400581 [Homo sapiens] 243 3e-65
gi|5729856 GRB2-related adaptor protein [Homo sapiens] 204 1e-53
gi|4504111 growth factor receptor-bound protein 2 isoform 1 [Hom... 144 2e-35
gi|4758476 GRB2-related adaptor protein 2 [Homo sapiens] 95 1e-20
gi|45359859 growth factor receptor-bound protein 2 isoform 2 [Ho... 92 7e-20
gi|5453754 NCK adaptor protein 1 [Homo sapiens] 81 2e-16
gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a... 79 6e-16
gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b... 79 6e-16
gi|187475373 c-src tyrosine kinase [Homo sapiens] 79 8e-16
gi|4758078 c-src tyrosine kinase [Homo sapiens] 79 8e-16
gi|153266778 arg tyrosine kinase isoform c [Homo sapiens] 78 1e-15
gi|6382062 arg tyrosine kinase isoform b [Homo sapiens] 78 1e-15
gi|209862778 arg tyrosine kinase isoform e [Homo sapiens] 78 1e-15
gi|209862772 arg tyrosine kinase isoform d [Homo sapiens] 78 1e-15
gi|153266757 arg tyrosine kinase isoform a [Homo sapiens] 78 1e-15
gi|112789548 lymphocyte-specific protein tyrosine kinase precurs... 77 2e-15
gi|112789546 lymphocyte-specific protein tyrosine kinase precurs... 77 2e-15
gi|4503787 fyn-related kinase [Homo sapiens] 76 6e-15
gi|23510364 protein-tyrosine kinase fyn isoform c [Homo sapiens] 75 1e-14
gi|23510362 protein-tyrosine kinase fyn isoform b [Homo sapiens] 75 1e-14
gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens] 75 1e-14
gi|162287326 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog ... 74 3e-14
gi|4505055 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog is... 74 3e-14
gi|112382244 proto-oncogene tyrosine-protein kinase FGR [Homo sa... 73 4e-14
gi|112382241 proto-oncogene tyrosine-protein kinase FGR [Homo sa... 73 4e-14
gi|4885235 proto-oncogene tyrosine-protein kinase FGR [Homo sapi... 73 4e-14
gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens] 73 5e-14
gi|52630425 NCK adaptor protein 2 isoform A [Homo sapiens] 72 9e-14
gi|52630423 NCK adaptor protein 2 isoform A [Homo sapiens] 72 9e-14
gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo sap... 71 2e-13
>gi|193220941 hypothetical protein LOC400581 [Homo sapiens]
Length = 118
Score = 243 bits (619), Expect = 3e-65
Identities = 118/118 (100%), Positives = 118/118 (100%)
Query: 1 MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIRVKPHPW 60
MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIRVKPHPW
Sbjct: 1 MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIRVKPHPW 60
Query: 61 YSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNNRAQRGPCLGPKSHSRLG 118
YSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNNRAQRGPCLGPKSHSRLG
Sbjct: 61 YSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNNRAQRGPCLGPKSHSRLG 118
>gi|5729856 GRB2-related adaptor protein [Homo sapiens]
Length = 217
Score = 204 bits (519), Expect = 1e-53
Identities = 100/100 (100%), Positives = 100/100 (100%)
Query: 1 MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIRVKPHPW 60
MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIRVKPHPW
Sbjct: 1 MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIRVKPHPW 60
Query: 61 YSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVN 100
YSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVN
Sbjct: 61 YSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVN 100
Score = 38.5 bits (88), Expect = 0.001
Identities = 15/50 (30%), Positives = 30/50 (60%), Gaps = 1/50 (2%)
Query: 5 ALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIR 54
A + F A + +L+F +GD +++L D +W++ G GF P++Y++
Sbjct: 165 AQFDFSAQDPSQLSFRRGDIIEVLE-RPDPHWWRGRSCGRVGFFPRSYVQ 213
>gi|4504111 growth factor receptor-bound protein 2 isoform 1 [Homo
sapiens]
Length = 217
Score = 144 bits (362), Expect = 2e-35
Identities = 66/99 (66%), Positives = 81/99 (81%)
Query: 1 MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIRVKPHPW 60
ME++A Y F+AT DEL+F +GD LK+LN E DQNWYKAEL G +GFIPKNYI +KPHPW
Sbjct: 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW 60
Query: 61 YSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSV 99
+ G+I R AEE+L K+ H GAFLIRESES+PG+FS+SV
Sbjct: 61 FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSV 99
Score = 43.9 bits (102), Expect = 3e-05
Identities = 18/49 (36%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
Query: 5 ALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYI 53
AL+ F E EL F +GD + +++ D NW+K G G P+NY+
Sbjct: 163 ALFDFDPQEDGELGFRRGDFIHVMD-NSDPNWWKGACHGQTGMFPRNYV 210
>gi|4758476 GRB2-related adaptor protein 2 [Homo sapiens]
Length = 330
Score = 94.7 bits (234), Expect = 1e-20
Identities = 47/101 (46%), Positives = 72/101 (71%), Gaps = 3/101 (2%)
Query: 1 MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIRVKPHPW 60
ME+VA + F A+ DEL+F+ GD LKIL+ +++ W+KAEL EG++PKN+I ++ W
Sbjct: 1 MEAVAKFDFTASGEDELSFHTGDVLKILSNQEE--WFKAELGSQEGYVPKNFIDIQFPKW 58
Query: 61 YSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNN 101
+ +SR AE +LM + +G F+IR S+SSPG+FS+SV +
Sbjct: 59 FHEGLSRHQAENLLMGK-EVGFFIIRASQSSPGDFSISVRH 98
Score = 42.7 bits (99), Expect = 6e-05
Identities = 18/49 (36%), Positives = 29/49 (59%), Gaps = 1/49 (2%)
Query: 5 ALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYI 53
ALY F+A E DEL F+ G+ +++L+ + +W+ L G P NY+
Sbjct: 278 ALYDFEALEDDELGFHSGEVVEVLD-SSNPSWWTGRLHNKLGLFPANYV 325
>gi|45359859 growth factor receptor-bound protein 2 isoform 2
[Homo sapiens]
Length = 176
Score = 92.4 bits (228), Expect = 7e-20
Identities = 40/60 (66%), Positives = 49/60 (81%)
Query: 1 MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIRVKPHPW 60
ME++A Y F+AT DEL+F +GD LK+LN E DQNWYKAEL G +GFIPKNYI +KPHP+
Sbjct: 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPF 60
Score = 43.9 bits (102), Expect = 3e-05
Identities = 18/49 (36%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
Query: 5 ALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYI 53
AL+ F E EL F +GD + +++ D NW+K G G P+NY+
Sbjct: 122 ALFDFDPQEDGELGFRRGDFIHVMD-NSDPNWWKGACHGQTGMFPRNYV 169
>gi|5453754 NCK adaptor protein 1 [Homo sapiens]
Length = 377
Score = 81.3 bits (199), Expect = 2e-16
Identities = 45/125 (36%), Positives = 66/125 (52%), Gaps = 30/125 (24%)
Query: 5 ALYSFQATESDELAFNKGDTLKILNM-EDDQNWYKA-ELRGVEGFIPKNYIRVKPH---- 58
ALY F ++ +EL F KGD + ++ E+D W+K ++ G+ G +PKNY+ V +
Sbjct: 197 ALYPFSSSNDEELNFEKGDVMDVIEKPENDPEWWKCRKINGMVGLVPKNYVTVMQNNPLT 256
Query: 59 ------------------------PWYSGRISRQLAEEILMKRNHLGAFLIRESESSPGE 94
PWY G+++R AE L +R H G FLIR+SESSP +
Sbjct: 257 SGLEPSPPQCDYIRPSLTGKFAGNPWYYGKVTRHQAEMALNERGHEGDFLIRDSESSPND 316
Query: 95 FSVSV 99
FSVS+
Sbjct: 317 FSVSL 321
Score = 33.1 bits (74), Expect = 0.048
Identities = 19/73 (26%), Positives = 35/73 (47%), Gaps = 4/73 (5%)
Query: 1 MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIRVK---P 57
M + +++ A DEL+ KG + ++ D W++ G G+ P NY+ + P
Sbjct: 109 MPAYVKFNYMAEREDELSLIKGTKVIVMEKCSD-GWWRGSYNGQVGWFPSNYVTEEGDSP 167
Query: 58 HPWYSGRISRQLA 70
+ G +S +LA
Sbjct: 168 LGDHVGSLSEKLA 180
>gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a
[Homo sapiens]
Length = 1130
Score = 79.3 bits (194), Expect = 6e-16
Identities = 40/100 (40%), Positives = 63/100 (63%), Gaps = 5/100 (5%)
Query: 4 VALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYI----RVKPHP 59
VALY F A+ + L+ KG+ L++L + W +A+ + +G++P NYI ++ H
Sbjct: 67 VALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHS 126
Query: 60 WYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSV 99
WY G +SR AE +L + G+FL+RESESSPG+ S+S+
Sbjct: 127 WYHGPVSRNAAEYLLSSGIN-GSFLVRESESSPGQRSISL 165
>gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b
[Homo sapiens]
Length = 1149
Score = 79.3 bits (194), Expect = 6e-16
Identities = 40/100 (40%), Positives = 63/100 (63%), Gaps = 5/100 (5%)
Query: 4 VALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYI----RVKPHP 59
VALY F A+ + L+ KG+ L++L + W +A+ + +G++P NYI ++ H
Sbjct: 86 VALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHS 145
Query: 60 WYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSV 99
WY G +SR AE +L + G+FL+RESESSPG+ S+S+
Sbjct: 146 WYHGPVSRNAAEYLLSSGIN-GSFLVRESESSPGQRSISL 184
>gi|187475373 c-src tyrosine kinase [Homo sapiens]
Length = 450
Score = 79.0 bits (193), Expect = 8e-16
Identities = 46/127 (36%), Positives = 69/127 (54%), Gaps = 19/127 (14%)
Query: 2 ESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELR-GVEGFIPKNYI------- 53
E +A Y+F T +L F KGD L I+ + D NWYKA+ + G EG IP NY+
Sbjct: 13 ECIAKYNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKREGVK 72
Query: 54 ---RVKPHPWYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNNRAQRGPCLG 110
++ PW+ G+I+R+ AE +L G FL+RES + PG++++ V+ C G
Sbjct: 73 AGTKLSLMPWFHGKITREQAERLLYP-PETGLFLVRESTNYPGDYTLCVS-------CDG 124
Query: 111 PKSHSRL 117
H R+
Sbjct: 125 KVEHYRI 131
>gi|4758078 c-src tyrosine kinase [Homo sapiens]
Length = 450
Score = 79.0 bits (193), Expect = 8e-16
Identities = 46/127 (36%), Positives = 69/127 (54%), Gaps = 19/127 (14%)
Query: 2 ESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELR-GVEGFIPKNYI------- 53
E +A Y+F T +L F KGD L I+ + D NWYKA+ + G EG IP NY+
Sbjct: 13 ECIAKYNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKREGVK 72
Query: 54 ---RVKPHPWYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNNRAQRGPCLG 110
++ PW+ G+I+R+ AE +L G FL+RES + PG++++ V+ C G
Sbjct: 73 AGTKLSLMPWFHGKITREQAERLLYP-PETGLFLVRESTNYPGDYTLCVS-------CDG 124
Query: 111 PKSHSRL 117
H R+
Sbjct: 125 KVEHYRI 131
>gi|153266778 arg tyrosine kinase isoform c [Homo sapiens]
Length = 1167
Score = 78.2 bits (191), Expect = 1e-15
Identities = 39/100 (39%), Positives = 61/100 (61%), Gaps = 5/100 (5%)
Query: 4 VALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYI----RVKPHP 59
VALY F A+ + L+ KG+ L++L + W + + +G++P NYI ++ H
Sbjct: 98 VALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHS 157
Query: 60 WYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSV 99
WY G +SR AE +L + G+FL+RESESSPG+ S+S+
Sbjct: 158 WYHGPVSRSAAEYLLSSLIN-GSFLVRESESSPGQLSISL 196
>gi|6382062 arg tyrosine kinase isoform b [Homo sapiens]
Length = 1182
Score = 78.2 bits (191), Expect = 1e-15
Identities = 39/100 (39%), Positives = 61/100 (61%), Gaps = 5/100 (5%)
Query: 4 VALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYI----RVKPHP 59
VALY F A+ + L+ KG+ L++L + W + + +G++P NYI ++ H
Sbjct: 113 VALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHS 172
Query: 60 WYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSV 99
WY G +SR AE +L + G+FL+RESESSPG+ S+S+
Sbjct: 173 WYHGPVSRSAAEYLLSSLIN-GSFLVRESESSPGQLSISL 211
>gi|209862778 arg tyrosine kinase isoform e [Homo sapiens]
Length = 542
Score = 78.2 bits (191), Expect = 1e-15
Identities = 39/100 (39%), Positives = 61/100 (61%), Gaps = 5/100 (5%)
Query: 4 VALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYI----RVKPHP 59
VALY F A+ + L+ KG+ L++L + W + + +G++P NYI ++ H
Sbjct: 92 VALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHS 151
Query: 60 WYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSV 99
WY G +SR AE +L + G+FL+RESESSPG+ S+S+
Sbjct: 152 WYHGPVSRSAAEYLLSSLIN-GSFLVRESESSPGQLSISL 190
>gi|209862772 arg tyrosine kinase isoform d [Homo sapiens]
Length = 1064
Score = 78.2 bits (191), Expect = 1e-15
Identities = 39/100 (39%), Positives = 61/100 (61%), Gaps = 5/100 (5%)
Query: 4 VALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYI----RVKPHP 59
VALY F A+ + L+ KG+ L++L + W + + +G++P NYI ++ H
Sbjct: 98 VALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHS 157
Query: 60 WYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSV 99
WY G +SR AE +L + G+FL+RESESSPG+ S+S+
Sbjct: 158 WYHGPVSRSAAEYLLSSLIN-GSFLVRESESSPGQLSISL 196
>gi|153266757 arg tyrosine kinase isoform a [Homo sapiens]
Length = 1146
Score = 78.2 bits (191), Expect = 1e-15
Identities = 39/100 (39%), Positives = 61/100 (61%), Gaps = 5/100 (5%)
Query: 4 VALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYI----RVKPHP 59
VALY F A+ + L+ KG+ L++L + W + + +G++P NYI ++ H
Sbjct: 77 VALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHS 136
Query: 60 WYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSV 99
WY G +SR AE +L + G+FL+RESESSPG+ S+S+
Sbjct: 137 WYHGPVSRSAAEYLLSSLIN-GSFLVRESESSPGQLSISL 175
>gi|112789548 lymphocyte-specific protein tyrosine kinase precursor
[Homo sapiens]
Length = 509
Score = 77.4 bits (189), Expect = 2e-15
Identities = 44/105 (41%), Positives = 67/105 (63%), Gaps = 9/105 (8%)
Query: 4 VALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAE--LRGVEGFIPKNYI----RVKP 57
+AL+S++ + +L F KG+ L+IL E W+KA+ G EGFIP N++ ++P
Sbjct: 67 IALHSYEPSHDGDLGFEKGEQLRIL--EQSGEWWKAQSLTTGQEGFIPFNFVAKANSLEP 124
Query: 58 HPWYSGRISRQLAE-EILMKRNHLGAFLIRESESSPGEFSVSVNN 101
PW+ +SR+ AE ++L N G+FLIRESES+ G FS+SV +
Sbjct: 125 EPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRD 169
>gi|112789546 lymphocyte-specific protein tyrosine kinase precursor
[Homo sapiens]
Length = 509
Score = 77.4 bits (189), Expect = 2e-15
Identities = 44/105 (41%), Positives = 67/105 (63%), Gaps = 9/105 (8%)
Query: 4 VALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAE--LRGVEGFIPKNYI----RVKP 57
+AL+S++ + +L F KG+ L+IL E W+KA+ G EGFIP N++ ++P
Sbjct: 67 IALHSYEPSHDGDLGFEKGEQLRIL--EQSGEWWKAQSLTTGQEGFIPFNFVAKANSLEP 124
Query: 58 HPWYSGRISRQLAE-EILMKRNHLGAFLIRESESSPGEFSVSVNN 101
PW+ +SR+ AE ++L N G+FLIRESES+ G FS+SV +
Sbjct: 125 EPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRD 169
>gi|4503787 fyn-related kinase [Homo sapiens]
Length = 505
Score = 75.9 bits (185), Expect = 6e-15
Identities = 42/109 (38%), Positives = 65/109 (59%), Gaps = 13/109 (11%)
Query: 4 VALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAEL--------RGVEGFIPKNYIR- 54
VAL+ +QA +++L+F GD L++L+ + W+ L + ++G+IP NY+
Sbjct: 48 VALFDYQARTAEDLSFRAGDKLQVLDTLHEGWWFARHLEKRRDGSSQQLQGYIPSNYVAE 107
Query: 55 ---VKPHPWYSGRISRQLAE-EILMKRNHLGAFLIRESESSPGEFSVSV 99
++ PW+ G I R AE ++L N G+FLIRESES GEFS+SV
Sbjct: 108 DRSLQAEPWFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSV 156
>gi|23510364 protein-tyrosine kinase fyn isoform c [Homo sapiens]
Length = 482
Score = 74.7 bits (182), Expect = 1e-14
Identities = 40/104 (38%), Positives = 63/104 (60%), Gaps = 6/104 (5%)
Query: 4 VALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAEL-RGVEGFIPKNYI----RVKPH 58
VALY ++A D+L+F+KG+ +ILN + W L G G+IP NY+ ++
Sbjct: 88 VALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQAE 147
Query: 59 PWYSGRISRQLAE-EILMKRNHLGAFLIRESESSPGEFSVSVNN 101
WY G++ R+ AE ++L N G FLIRESE++ G +S+S+ +
Sbjct: 148 EWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRD 191
>gi|23510362 protein-tyrosine kinase fyn isoform b [Homo sapiens]
Length = 534
Score = 74.7 bits (182), Expect = 1e-14
Identities = 40/104 (38%), Positives = 63/104 (60%), Gaps = 6/104 (5%)
Query: 4 VALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAEL-RGVEGFIPKNYI----RVKPH 58
VALY ++A D+L+F+KG+ +ILN + W L G G+IP NY+ ++
Sbjct: 88 VALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQAE 147
Query: 59 PWYSGRISRQLAE-EILMKRNHLGAFLIRESESSPGEFSVSVNN 101
WY G++ R+ AE ++L N G FLIRESE++ G +S+S+ +
Sbjct: 148 EWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRD 191
>gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens]
Length = 537
Score = 74.7 bits (182), Expect = 1e-14
Identities = 40/104 (38%), Positives = 63/104 (60%), Gaps = 6/104 (5%)
Query: 4 VALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAEL-RGVEGFIPKNYI----RVKPH 58
VALY ++A D+L+F+KG+ +ILN + W L G G+IP NY+ ++
Sbjct: 88 VALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQAE 147
Query: 59 PWYSGRISRQLAE-EILMKRNHLGAFLIRESESSPGEFSVSVNN 101
WY G++ R+ AE ++L N G FLIRESE++ G +S+S+ +
Sbjct: 148 EWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRD 191
>gi|162287326 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
isoform B [Homo sapiens]
Length = 491
Score = 73.6 bits (179), Expect = 3e-14
Identities = 44/105 (41%), Positives = 64/105 (60%), Gaps = 9/105 (8%)
Query: 4 VALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAE--LRGVEGFIPKNYI----RVKP 57
VALY + D+L+F KG+ +K+L E+ W+KA+ L EGFIP NY+ ++
Sbjct: 48 VALYPYDGIHPDDLSFKKGEKMKVL--EEHGEWWKAKSLLTKKEGFIPSNYVAKLNTLET 105
Query: 58 HPWYSGRISRQLAE-EILMKRNHLGAFLIRESESSPGEFSVSVNN 101
W+ I+R+ AE ++L N GAFLIRESE+ G FS+SV +
Sbjct: 106 EEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRD 150
>gi|4505055 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
isoform A [Homo sapiens]
Length = 512
Score = 73.6 bits (179), Expect = 3e-14
Identities = 44/105 (41%), Positives = 64/105 (60%), Gaps = 9/105 (8%)
Query: 4 VALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAE--LRGVEGFIPKNYI----RVKP 57
VALY + D+L+F KG+ +K+L E+ W+KA+ L EGFIP NY+ ++
Sbjct: 69 VALYPYDGIHPDDLSFKKGEKMKVL--EEHGEWWKAKSLLTKKEGFIPSNYVAKLNTLET 126
Query: 58 HPWYSGRISRQLAE-EILMKRNHLGAFLIRESESSPGEFSVSVNN 101
W+ I+R+ AE ++L N GAFLIRESE+ G FS+SV +
Sbjct: 127 EEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRD 171
>gi|112382244 proto-oncogene tyrosine-protein kinase FGR [Homo
sapiens]
Length = 529
Score = 73.2 bits (178), Expect = 4e-14
Identities = 41/104 (39%), Positives = 60/104 (57%), Gaps = 6/104 (5%)
Query: 4 VALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAEL-RGVEGFIPKNYI----RVKPH 58
+ALY ++A D+L F KG+ ILN + W L G G IP NY+ ++
Sbjct: 83 IALYDYEARTEDDLTFTKGEKFHILNNTEGDWWEARSLSSGKTGCIPSNYVAPVDSIQAE 142
Query: 59 PWYSGRISRQLAE-EILMKRNHLGAFLIRESESSPGEFSVSVNN 101
WY G+I R+ AE ++L N GAFLIRESE++ G +S+S+ +
Sbjct: 143 EWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRD 186
>gi|112382241 proto-oncogene tyrosine-protein kinase FGR [Homo
sapiens]
Length = 529
Score = 73.2 bits (178), Expect = 4e-14
Identities = 41/104 (39%), Positives = 60/104 (57%), Gaps = 6/104 (5%)
Query: 4 VALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAEL-RGVEGFIPKNYI----RVKPH 58
+ALY ++A D+L F KG+ ILN + W L G G IP NY+ ++
Sbjct: 83 IALYDYEARTEDDLTFTKGEKFHILNNTEGDWWEARSLSSGKTGCIPSNYVAPVDSIQAE 142
Query: 59 PWYSGRISRQLAE-EILMKRNHLGAFLIRESESSPGEFSVSVNN 101
WY G+I R+ AE ++L N GAFLIRESE++ G +S+S+ +
Sbjct: 143 EWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRD 186
>gi|4885235 proto-oncogene tyrosine-protein kinase FGR [Homo
sapiens]
Length = 529
Score = 73.2 bits (178), Expect = 4e-14
Identities = 41/104 (39%), Positives = 60/104 (57%), Gaps = 6/104 (5%)
Query: 4 VALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAEL-RGVEGFIPKNYI----RVKPH 58
+ALY ++A D+L F KG+ ILN + W L G G IP NY+ ++
Sbjct: 83 IALYDYEARTEDDLTFTKGEKFHILNNTEGDWWEARSLSSGKTGCIPSNYVAPVDSIQAE 142
Query: 59 PWYSGRISRQLAE-EILMKRNHLGAFLIRESESSPGEFSVSVNN 101
WY G+I R+ AE ++L N GAFLIRESE++ G +S+S+ +
Sbjct: 143 EWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRD 186
>gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens]
Length = 543
Score = 72.8 bits (177), Expect = 5e-14
Identities = 37/105 (35%), Positives = 66/105 (62%), Gaps = 8/105 (7%)
Query: 4 VALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAE--LRGVEGFIPKNYI----RVKP 57
VALY ++A +++L+F KG+ +I+N + +W++A G G+IP NY+ ++
Sbjct: 97 VALYDYEARTTEDLSFKKGERFQIIN-NTEGDWWEARSIATGKNGYIPSNYVAPADSIQA 155
Query: 58 HPWYSGRISRQLAEEILMK-RNHLGAFLIRESESSPGEFSVSVNN 101
WY G++ R+ AE +L+ N G FL+RESE++ G +S+S+ +
Sbjct: 156 EEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRD 200
>gi|52630425 NCK adaptor protein 2 isoform A [Homo sapiens]
Length = 380
Score = 72.0 bits (175), Expect = 9e-14
Identities = 45/122 (36%), Positives = 63/122 (51%), Gaps = 28/122 (22%)
Query: 6 LYSFQATESDELAFNKGDTLKILNM-EDDQNWYKAE-LRGVEGFIPKNYIRVKP-----H 58
LY F + +EL F KG+T++++ E+D W+K + RG G +PKNY+ V H
Sbjct: 203 LYPFSSVTEEELNFEKGETMEVIEKPENDPEWWKCKNARGQVGLVPKNYVVVLSDGPALH 262
Query: 59 P---------------------WYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSV 97
P WY G ++R AE L +R G FLIR+SESSP +FSV
Sbjct: 263 PAHAPQISYTGPSSSGRFAGREWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSV 322
Query: 98 SV 99
S+
Sbjct: 323 SL 324
Score = 31.6 bits (70), Expect = 0.14
Identities = 13/47 (27%), Positives = 24/47 (51%), Gaps = 1/47 (2%)
Query: 7 YSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYI 53
+++ A DEL+ KG + ++ D W++ G G+ P NY+
Sbjct: 120 FAYVAEREDELSLVKGSRVTVMEKCSD-GWWRGSYNGQIGWFPSNYV 165
>gi|52630423 NCK adaptor protein 2 isoform A [Homo sapiens]
Length = 380
Score = 72.0 bits (175), Expect = 9e-14
Identities = 45/122 (36%), Positives = 63/122 (51%), Gaps = 28/122 (22%)
Query: 6 LYSFQATESDELAFNKGDTLKILNM-EDDQNWYKAE-LRGVEGFIPKNYIRVKP-----H 58
LY F + +EL F KG+T++++ E+D W+K + RG G +PKNY+ V H
Sbjct: 203 LYPFSSVTEEELNFEKGETMEVIEKPENDPEWWKCKNARGQVGLVPKNYVVVLSDGPALH 262
Query: 59 P---------------------WYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSV 97
P WY G ++R AE L +R G FLIR+SESSP +FSV
Sbjct: 263 PAHAPQISYTGPSSSGRFAGREWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSV 322
Query: 98 SV 99
S+
Sbjct: 323 SL 324
Score = 31.6 bits (70), Expect = 0.14
Identities = 13/47 (27%), Positives = 24/47 (51%), Gaps = 1/47 (2%)
Query: 7 YSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYI 53
+++ A DEL+ KG + ++ D W++ G G+ P NY+
Sbjct: 120 FAYVAEREDELSLVKGSRVTVMEKCSD-GWWRGSYNGQIGWFPSNYV 165
>gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo
sapiens]
Length = 536
Score = 71.2 bits (173), Expect = 2e-13
Identities = 37/104 (35%), Positives = 63/104 (60%), Gaps = 6/104 (5%)
Query: 4 VALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAEL-RGVEGFIPKNYI----RVKPH 58
VALY +++ +L+F KG+ L+I+N + W L G G+IP NY+ ++
Sbjct: 90 VALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAE 149
Query: 59 PWYSGRISRQLAEEILMK-RNHLGAFLIRESESSPGEFSVSVNN 101
WY G+I+R+ +E +L+ N G FL+RESE++ G + +SV++
Sbjct: 150 EWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSD 193
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,468,458
Number of Sequences: 37866
Number of extensions: 173712
Number of successful extensions: 1077
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 243
Number of HSP's successfully gapped in prelim test: 107
Number of HSP's that attempted gapping in prelim test: 491
Number of HSP's gapped (non-prelim): 455
length of query: 118
length of database: 18,247,518
effective HSP length: 88
effective length of query: 30
effective length of database: 14,915,310
effective search space: 447459300
effective search space used: 447459300
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.