Search of human proteins with 193083221

Search of human proteins with 193083221

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|193083221 mast cell immunoreceptor signal transducer [Homo
sapiens]
         (428 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|193083221 mast cell immunoreceptor signal transducer [Homo sa...   889   0.0  
gi|5031855 lymphocyte cytosolic protein 2 [Homo sapiens]              127   3e-29
gi|166235901 B-cell linker isoform 2 [Homo sapiens]                   111   1e-24
gi|7019535 B-cell linker isoform 1 [Homo sapiens]                     106   4e-23
gi|38348280 SH2 domain containing 6 [Homo sapiens]                     70   4e-12
gi|5453754 NCK adaptor protein 1 [Homo sapiens]                        51   2e-06
gi|32455252 phosphoinositide-3-kinase, regulatory subunit 1 (alp...    50   5e-06
gi|32455250 phosphoinositide-3-kinase, regulatory subunit 1 (alp...    50   5e-06
gi|32455248 phosphoinositide-3-kinase, regulatory subunit 1 (alp...    50   5e-06
gi|33356177 protein tyrosine phosphatase, non-receptor type 11 [...    49   7e-06
gi|5729856 GRB2-related adaptor protein [Homo sapiens]                 49   7e-06
gi|40254823 SH2 containing inositol phosphatase isoform b [Homo ...    47   3e-05
gi|64085167 SH2 containing inositol phosphatase isoform a [Homo ...    47   3e-05
gi|4826908 phosphoinositide-3-kinase, regulatory subunit 2 (beta...    47   4e-05
gi|52630425 NCK adaptor protein 2 isoform A [Homo sapiens]             46   6e-05
gi|52630423 NCK adaptor protein 2 isoform A [Homo sapiens]             46   6e-05
gi|33598948 phospholipase C, gamma 1 isoform a [Homo sapiens]          45   1e-04
gi|33598946 phospholipase C, gamma 1 isoform b [Homo sapiens]          45   1e-04
gi|166795247 phosphoinositide-3-kinase, regulatory subunit 3 (p5...    45   1e-04
gi|166795245 phosphoinositide-3-kinase, regulatory subunit 3 (p5...    45   1e-04
gi|4885153 v-crk sarcoma virus CT10 oncogene homolog (avian)-lik...    44   3e-04
gi|158631203 dual adaptor of phosphotyrosine and 3-phosphoinosit...    43   5e-04
gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo sap...    42   0.001
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]         41   0.002
gi|4557377 Bruton agammaglobulinemia tyrosine kinase [Homo sapiens]    41   0.002
gi|224586793 src homology 2 domain-containing transforming prote...    40   0.005
gi|150378503 leiomodin 2 (cardiac) [Homo sapiens]                      40   0.005
gi|222352122 hypothetical protein LOC284297 [Homo sapiens]             39   0.007
gi|197304715 vav 2 guanine nucleotide exchange factor isoform 1 ...    39   0.007
gi|40549448 vav 2 guanine nucleotide exchange factor isoform 2 [...    39   0.007

>gi|193083221 mast cell immunoreceptor signal transducer [Homo
           sapiens]
          Length = 428

 Score =  889 bits (2298), Expect = 0.0
 Identities = 428/428 (100%), Positives = 428/428 (100%)

Query: 1   MNRQGNRKTTKEGSNDLKFQNFSLPKNRSWPRINSATGQYQRMNKPLLDWERNFAAVLDG 60
           MNRQGNRKTTKEGSNDLKFQNFSLPKNRSWPRINSATGQYQRMNKPLLDWERNFAAVLDG
Sbjct: 1   MNRQGNRKTTKEGSNDLKFQNFSLPKNRSWPRINSATGQYQRMNKPLLDWERNFAAVLDG 60

Query: 61  AKGHSDDDYDDPELRMEETWQSIKILPARPIKESEYADTHYFKVAMDTPLPLDTRTSISI 120
           AKGHSDDDYDDPELRMEETWQSIKILPARPIKESEYADTHYFKVAMDTPLPLDTRTSISI
Sbjct: 61  AKGHSDDDYDDPELRMEETWQSIKILPARPIKESEYADTHYFKVAMDTPLPLDTRTSISI 120

Query: 121 GQPTWNTQTRLERVDKPISKDVRSQNIKGDASVRKNKIPLPPPRPLITLPKKYQPLPPEP 180
           GQPTWNTQTRLERVDKPISKDVRSQNIKGDASVRKNKIPLPPPRPLITLPKKYQPLPPEP
Sbjct: 121 GQPTWNTQTRLERVDKPISKDVRSQNIKGDASVRKNKIPLPPPRPLITLPKKYQPLPPEP 180

Query: 181 ESSRPPLSQRHTFPEVQRMPSQISLRDLSEVLEAEKVPHNQRKPESTHLLENQNTQEIPL 240
           ESSRPPLSQRHTFPEVQRMPSQISLRDLSEVLEAEKVPHNQRKPESTHLLENQNTQEIPL
Sbjct: 181 ESSRPPLSQRHTFPEVQRMPSQISLRDLSEVLEAEKVPHNQRKPESTHLLENQNTQEIPL 240

Query: 241 AISSSSFTTSNHSVQNRDHRGGMQPCSPQRCQPPASCSPHENILPYKYTSWRPPFPKRSD 300
           AISSSSFTTSNHSVQNRDHRGGMQPCSPQRCQPPASCSPHENILPYKYTSWRPPFPKRSD
Sbjct: 241 AISSSSFTTSNHSVQNRDHRGGMQPCSPQRCQPPASCSPHENILPYKYTSWRPPFPKRSD 300

Query: 301 RKDVQHNEWYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVFYENKVYNVK 360
           RKDVQHNEWYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVFYENKVYNVK
Sbjct: 301 RKDVQHNEWYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVFYENKVYNVK 360

Query: 361 IRFLERNQQFALGTGLRGDEKFDSVEDIIEHYKNFPIILIDGKDKTGVHRKQCHLTQPLP 420
           IRFLERNQQFALGTGLRGDEKFDSVEDIIEHYKNFPIILIDGKDKTGVHRKQCHLTQPLP
Sbjct: 361 IRFLERNQQFALGTGLRGDEKFDSVEDIIEHYKNFPIILIDGKDKTGVHRKQCHLTQPLP 420

Query: 421 LTRHLLPL 428
           LTRHLLPL
Sbjct: 421 LTRHLLPL 428


>gi|5031855 lymphocyte cytosolic protein 2 [Homo sapiens]
          Length = 533

 Score =  127 bits (318), Expect = 3e-29
 Identities = 117/404 (28%), Positives = 171/404 (42%), Gaps = 71/404 (17%)

Query: 66  DDDYDDPELRMEETWQSIKILPARPIKESE--YADTHYF-KVAMDTPLPLDTRTSISIGQ 122
           D DY+ P    EE  Q+  ILPA+P   S   Y D     K     P+P     +     
Sbjct: 142 DADYEPPPSNDEEALQN-SILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPP 200

Query: 123 PTWNTQTRLERVDKPISKDVRSQNIKGDASVRKNKIPLP-------PPRPLITLPKKYQP 175
           P     + L        +  RS+N K        K+P P       PP     L +   P
Sbjct: 201 PAGRNHSPLPPPQTNHEEPSRSRNHK------TAKLPAPSIDRSTKPP-----LDRSLAP 249

Query: 176 LPPEPES--SRPPLSQRHTFP----------EVQR--MPSQISLRDLSEVLEAEKVP--- 218
              EP +   +PP S + + P          ++Q+  +P      + S  L  +K P   
Sbjct: 250 FDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPK 309

Query: 219 ---------------HNQRKPESTHLLENQNT-----------QEIPLAISSSSFTTSNH 252
                          H +  P+   L  + NT             +P +    +F+ SN 
Sbjct: 310 HGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNS 369

Query: 253 SVQNRDHRGGMQPCSPQRCQPPASCSPHENILPYKYTSWRPPFPKRSDRKDVQHNEWYIG 312
           S              P   +PP         LP      RPP P  ++ ++  + EWY+ 
Sbjct: 370 SFPQSASLPPYFSQGPSN-RPPIRAEGRNFPLPLPNKP-RPPSP--AEEENSLNEEWYVS 425

Query: 313 EYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVFYENKVYNVKIRFLERNQQFAL 372
             +R   E A  K N+DG+FLVRD S K+   PYVL V Y++KVYN++IR+ + +Q + L
Sbjct: 426 YITRPEAEAALRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDKVYNIQIRYQKESQVYLL 485

Query: 373 GTGLRGDEKFDSVEDIIEHYKNFPIILIDGKDKTGVHRKQCHLT 416
           GTGLRG E F SV DII++++  P++LIDGK++    R QC LT
Sbjct: 486 GTGLRGKEDFLSVSDIIDYFRKMPLLLIDGKNRGS--RYQCTLT 527


>gi|166235901 B-cell linker isoform 2 [Homo sapiens]
          Length = 433

 Score =  111 bits (277), Expect = 1e-24
 Identities = 97/370 (26%), Positives = 154/370 (41%), Gaps = 61/370 (16%)

Query: 61  AKGHSDDDYDDPELRMEETWQSIKILPARPIKESEYADTHYFKVAMDTPLPLDTRTSISI 120
           A+ ++DD Y+ P +  E       + PA P    EY D      +     P  ++T  S 
Sbjct: 88  AEENADDSYEPPPVEQETR----PVHPALPFARGEYIDNR----SSQRHSPPFSKTLPS- 138

Query: 121 GQPTWNTQTRLERVDKPISKDVRSQNIKGDASVRKNKIPLPPPRPLITLPKKY------- 173
            +P+W           P  K   +  +    +++K ++P P P+ L+     Y       
Sbjct: 139 -KPSW-----------PSEKARLTSTLPALTALQKPQVP-PKPKGLLEDEADYVVPVEDN 185

Query: 174 --QPLPPEPESSRPPLSQRHTFPEVQRMPSQISLRDLSEVLEAEKVPHNQRKPESTHLLE 231
               + P   SS PP   R++     + P   +   L     A K P    K  +T +  
Sbjct: 186 DENYIHPTESSSPPPEKGRNSGAWETKSPPPAAPSPLPR---AGKKPTTPLK--TTPVAS 240

Query: 232 NQNTQEIPLAISSSSFTTSNHSVQNRDHRGGM--QPCSPQRCQPPASCSPHENILPY-KY 288
            QN   +               +    HRG    Q        PPA    H+  +P  ++
Sbjct: 241 QQNASSV----------CEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRF 290

Query: 289 TSWRPP-----FPKRSDRKDVQHNE-------WYIGEYSRQAVEEAFMKENKDGSFLVRD 336
           T    P      P  S    +   E       WY G   R++ EEA  + NKDGSFL+R 
Sbjct: 291 TEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEALHRSNKDGSFLIRK 350

Query: 337 CSTKSKEEPYVLAVFYENKVYNVKIRFLERNQQFALGTGLRGDEKFDSVEDIIEHYKNFP 396
            S    ++PY L VF+  +VYN+ +RF+E  +Q+ALG    G+E F SV +II ++++ P
Sbjct: 351 SSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKNGEEYFGSVAEIIRNHQHSP 410

Query: 397 IILIDGKDKT 406
           ++LID ++ T
Sbjct: 411 LVLIDSQNNT 420


>gi|7019535 B-cell linker isoform 1 [Homo sapiens]
          Length = 456

 Score =  106 bits (265), Expect = 4e-23
 Identities = 101/389 (25%), Positives = 160/389 (41%), Gaps = 76/389 (19%)

Query: 61  AKGHSDDDYDDPELRMEETWQSIKILPARPIKESEYADTHYFKVAMDTPLPLDTRTSISI 120
           A+ ++DD Y+ P +  E       + PA P    EY D      +     P  ++T  S 
Sbjct: 88  AEENADDSYEPPPVEQETR----PVHPALPFARGEYIDNR----SSQRHSPPFSKTLPS- 138

Query: 121 GQPTWNTQTRLERVDKPISKDVRSQNIKGDASVRKNKIPLPPPRPLITLPKKY------- 173
            +P+W           P  K   +  +    +++K ++P P P+ L+     Y       
Sbjct: 139 -KPSW-----------PSEKARLTSTLPALTALQKPQVP-PKPKGLLEDEADYVVPVEDN 185

Query: 174 --QPLPPEPESSRPP----LSQRHTFPEVQRM---PSQISLRDLSEVLEAEK-------- 216
               + P   SS PP    +  R T P        P   S R+ S   E +         
Sbjct: 186 DENYIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGTASGRN-SGAWETKSPPPAAPSP 244

Query: 217 VPHNQRKP----ESTHLLENQNTQEIPLAISSSSFTTSNHSVQNRDHRGGM--QPCSPQR 270
           +P   +KP    ++T +   QN   +               +    HRG    Q      
Sbjct: 245 LPRAGKKPTTPLKTTPVASQQNASSV----------CEEKPIPAERHRGSSHRQEAVQSP 294

Query: 271 CQPPASCSPHENILPY-KYTSWRPP-----FPKRSDRKDVQHNE-------WYIGEYSRQ 317
             PPA    H+  +P  ++T    P      P  S    +   E       WY G   R+
Sbjct: 295 VFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACDRK 354

Query: 318 AVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVFYENKVYNVKIRFLERNQQFALGTGLR 377
           + EEA  + NKDGSFL+R  S    ++PY L VF+  +VYN+ +RF+E  +Q+ALG    
Sbjct: 355 SAEEALHRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKN 414

Query: 378 GDEKFDSVEDIIEHYKNFPIILIDGKDKT 406
           G+E F SV +II ++++ P++LID ++ T
Sbjct: 415 GEEYFGSVAEIIRNHQHSPLVLIDSQNNT 443


>gi|38348280 SH2 domain containing 6 [Homo sapiens]
          Length = 175

 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 36/104 (34%), Positives = 57/104 (54%), Gaps = 1/104 (0%)

Query: 299 SDRKDVQHNEWYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVFYENKVYN 358
           ++  D+    WY G   R AVE A +   KDG++ VR  S     +P+ LAV    +V+N
Sbjct: 55  AEDSDLLTQPWYSGNCDRYAVESALLHLQKDGAYTVRPSSGPHGSQPFTLAVLLRGRVFN 114

Query: 359 VKIRFLERNQQFALG-TGLRGDEKFDSVEDIIEHYKNFPIILID 401
           + IR L+  + +ALG  G   +E F SV  +++H+   P+ L+D
Sbjct: 115 IPIRRLDGGRHYALGREGRNREELFSSVAAMVQHFMWHPLPLVD 158


>gi|5453754 NCK adaptor protein 1 [Homo sapiens]
          Length = 377

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 27/99 (27%), Positives = 48/99 (48%), Gaps = 9/99 (9%)

Query: 307 NEWYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVFYENKVYNVKIRFLER 366
           N WY G+ +R   E A  +   +G FL+RD  +   +    L    +NK + V++    +
Sbjct: 280 NPWYYGKVTRHQAEMALNERGHEGDFLIRDSESSPNDFSVSLKAQGKNKHFKVQL----K 335

Query: 367 NQQFALGTGLRGDEKFDSVEDIIEHYKNFPIILIDGKDK 405
              + +     G  KF ++E+++EHYK  PI   +  +K
Sbjct: 336 ETVYCI-----GQRKFSTMEELVEHYKKAPIFTSEQGEK 369


>gi|32455252 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
           isoform 2 [Homo sapiens]
          Length = 454

 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 35/109 (32%), Positives = 54/109 (49%), Gaps = 14/109 (12%)

Query: 292 RPPFPKR------SDRKDVQHNEWYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEP 345
           +PP P        ++   +Q  EWY G+ SR+ V E  +++  DG+FLVRD STK   + 
Sbjct: 40  KPPKPTTVANNGMNNNMSLQDAEWYWGDISREEVNEK-LRDTADGTFLVRDASTKMHGD- 97

Query: 346 YVLAVFYENKVYNVKIRFLERNQQFALGTGLRGDEKFDSVEDIIEHYKN 394
           Y L +       N  I+   R+ ++     L     F SV ++I HY+N
Sbjct: 98  YTLTL--RKGGNNKLIKIFHRDGKYGFSDPL----TFSSVVELINHYRN 140



 Score = 36.2 bits (82), Expect = 0.059
 Identities = 25/102 (24%), Positives = 51/102 (50%), Gaps = 12/102 (11%)

Query: 300 DRKDVQHNE---WYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVFYENKV 356
           D +D+ H++   W +G  +R   E   ++  +DG+FLVR+    SK+  Y  +V  + +V
Sbjct: 342 DDEDLPHHDEKTWNVGSSNRNKAEN-LLRGKRDGTFLVRE---SSKQGCYACSVVVDGEV 397

Query: 357 YNVKIRFLERNQQFALGTGLRGDEKFDSVEDIIEHYKNFPII 398
            +  I        FA    L     + S+++++ HY++  ++
Sbjct: 398 KHCVINKTATGYGFAEPYNL-----YSSLKELVLHYQHTSLV 434


>gi|32455250 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
           isoform 3 [Homo sapiens]
          Length = 424

 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 35/109 (32%), Positives = 54/109 (49%), Gaps = 14/109 (12%)

Query: 292 RPPFPKR------SDRKDVQHNEWYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEP 345
           +PP P        ++   +Q  EWY G+ SR+ V E  +++  DG+FLVRD STK   + 
Sbjct: 10  KPPKPTTVANNGMNNNMSLQDAEWYWGDISREEVNEK-LRDTADGTFLVRDASTKMHGD- 67

Query: 346 YVLAVFYENKVYNVKIRFLERNQQFALGTGLRGDEKFDSVEDIIEHYKN 394
           Y L +       N  I+   R+ ++     L     F SV ++I HY+N
Sbjct: 68  YTLTL--RKGGNNKLIKIFHRDGKYGFSDPL----TFSSVVELINHYRN 110



 Score = 36.2 bits (82), Expect = 0.059
 Identities = 25/102 (24%), Positives = 51/102 (50%), Gaps = 12/102 (11%)

Query: 300 DRKDVQHNE---WYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVFYENKV 356
           D +D+ H++   W +G  +R   E   ++  +DG+FLVR+    SK+  Y  +V  + +V
Sbjct: 312 DDEDLPHHDEKTWNVGSSNRNKAEN-LLRGKRDGTFLVRE---SSKQGCYACSVVVDGEV 367

Query: 357 YNVKIRFLERNQQFALGTGLRGDEKFDSVEDIIEHYKNFPII 398
            +  I        FA    L     + S+++++ HY++  ++
Sbjct: 368 KHCVINKTATGYGFAEPYNL-----YSSLKELVLHYQHTSLV 404


>gi|32455248 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
           isoform 1 [Homo sapiens]
          Length = 724

 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 35/109 (32%), Positives = 54/109 (49%), Gaps = 14/109 (12%)

Query: 292 RPPFPKR------SDRKDVQHNEWYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEP 345
           +PP P        ++   +Q  EWY G+ SR+ V E  +++  DG+FLVRD STK   + 
Sbjct: 310 KPPKPTTVANNGMNNNMSLQDAEWYWGDISREEVNEK-LRDTADGTFLVRDASTKMHGD- 367

Query: 346 YVLAVFYENKVYNVKIRFLERNQQFALGTGLRGDEKFDSVEDIIEHYKN 394
           Y L +       N  I+   R+ ++     L     F SV ++I HY+N
Sbjct: 368 YTLTL--RKGGNNKLIKIFHRDGKYGFSDPL----TFSSVVELINHYRN 410



 Score = 36.2 bits (82), Expect = 0.059
 Identities = 25/102 (24%), Positives = 51/102 (50%), Gaps = 12/102 (11%)

Query: 300 DRKDVQHNE---WYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVFYENKV 356
           D +D+ H++   W +G  +R   E   ++  +DG+FLVR+    SK+  Y  +V  + +V
Sbjct: 612 DDEDLPHHDEKTWNVGSSNRNKAEN-LLRGKRDGTFLVRE---SSKQGCYACSVVVDGEV 667

Query: 357 YNVKIRFLERNQQFALGTGLRGDEKFDSVEDIIEHYKNFPII 398
            +  I        FA    L     + S+++++ HY++  ++
Sbjct: 668 KHCVINKTATGYGFAEPYNL-----YSSLKELVLHYQHTSLV 704


>gi|33356177 protein tyrosine phosphatase, non-receptor type 11
           [Homo sapiens]
          Length = 593

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 41/131 (31%), Positives = 61/131 (46%), Gaps = 26/131 (19%)

Query: 303 DVQHNEWYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVFY---------- 352
           D     W+ G  S +  E+   ++ K GSFLVR+  ++S    +VL+V            
Sbjct: 106 DPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRE--SQSHPGDFVLSVRTGDDKGESNDG 163

Query: 353 ENKVYNVKIRFLERNQQFALGTGLRGDEKFDSVEDIIEHYKNFPIILIDGKDKTGVHRKQ 412
           ++KV +V IR  E      L   + G E+FDS+ D++EHYK  P++   G          
Sbjct: 164 KSKVTHVMIRCQE------LKYDVGGGERFDSLTDLVEHYKKNPMVETLG--------TV 209

Query: 413 CHLTQPLPLTR 423
             L QPL  TR
Sbjct: 210 LQLKQPLNTTR 220


>gi|5729856 GRB2-related adaptor protein [Homo sapiens]
          Length = 217

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 29/94 (30%), Positives = 52/94 (55%), Gaps = 8/94 (8%)

Query: 304 VQHNEWYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVFYENKVYNVKIRF 363
           V+ + WY G  SRQ  EE  MK N  G+FL+R+  ++S    + ++V Y ++V + K+  
Sbjct: 55  VKPHPWYSGRISRQLAEEILMKRNHLGAFLIRE--SESSPGEFSVSVNYGDQVQHFKV-- 110

Query: 364 LERNQQFALGTGLRGDEKFDSVEDIIEHYKNFPI 397
                + A G     +EKF+S+ ++++ Y+   I
Sbjct: 111 ----LREASGKYFLWEEKFNSLNELVDFYRTTTI 140


>gi|40254823 SH2 containing inositol phosphatase isoform b [Homo
           sapiens]
          Length = 1188

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 38/116 (32%), Positives = 54/116 (46%), Gaps = 20/116 (17%)

Query: 309 WYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVFYENKVYNVKIRFLERNQ 368
           W  G  +R   EE   +  KDGSFLVR  +++S    Y L V Y N VY  +I   E ++
Sbjct: 5   WNHGNITRSKAEELLSRTGKDGSFLVR--ASESISRAYALCVLYRNCVYTYRILPNEDDK 62

Query: 369 ---QFALGTGLRGDEKFDSVEDIIEHYKNFPIILIDGKDKTGVHRKQCHLTQPLPL 421
              Q + G  +R    F  ++ +IE YK         K+  G+     HL  P+PL
Sbjct: 63  FTVQASEGVSMR---FFTKLDQLIEFYK---------KENMGL---VTHLQYPVPL 103


>gi|64085167 SH2 containing inositol phosphatase isoform a [Homo
           sapiens]
          Length = 1189

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 38/116 (32%), Positives = 54/116 (46%), Gaps = 20/116 (17%)

Query: 309 WYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVFYENKVYNVKIRFLERNQ 368
           W  G  +R   EE   +  KDGSFLVR  +++S    Y L V Y N VY  +I   E ++
Sbjct: 5   WNHGNITRSKAEELLSRTGKDGSFLVR--ASESISRAYALCVLYRNCVYTYRILPNEDDK 62

Query: 369 ---QFALGTGLRGDEKFDSVEDIIEHYKNFPIILIDGKDKTGVHRKQCHLTQPLPL 421
              Q + G  +R    F  ++ +IE YK         K+  G+     HL  P+PL
Sbjct: 63  FTVQASEGVSMR---FFTKLDQLIEFYK---------KENMGL---VTHLQYPVPL 103


>gi|4826908 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
           [Homo sapiens]
          Length = 728

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 32/91 (35%), Positives = 48/91 (52%), Gaps = 8/91 (8%)

Query: 304 VQHNEWYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVFYENKVYNVKIRF 363
           +Q  EWY G+ SR+ V E  +++  DG+FLVRD S+K + E Y L +       N  I+ 
Sbjct: 325 LQDAEWYWGDISREEVNEK-LRDTPDGTFLVRDASSKIQGE-YTLTL--RKGGNNKLIKV 380

Query: 364 LERNQQFALGTGLRGDEKFDSVEDIIEHYKN 394
             R+  +     L     F SV D+I HY++
Sbjct: 381 FHRDGHYGFSEPL----TFCSVVDLINHYRH 407



 Score = 36.6 bits (83), Expect = 0.045
 Identities = 26/102 (25%), Positives = 49/102 (48%), Gaps = 12/102 (11%)

Query: 300 DRKDVQHNE---WYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVFYENKV 356
           D  D+ H+E   WY+G+ +R   EE  +   +DG+FL+R+ S +     Y  +V  +   
Sbjct: 610 DEDDLPHHEERTWYVGKINRTQAEE-MLSGKRDGTFLIRESSQRG---CYACSVVVDGDT 665

Query: 357 YNVKIRFLERNQQFALGTGLRGDEKFDSVEDIIEHYKNFPII 398
            +  I        FA    L G     S+++++ HY++  ++
Sbjct: 666 KHCVIYRTATGFGFAEPYNLYG-----SLKELVLHYQHASLV 702


>gi|52630425 NCK adaptor protein 2 isoform A [Homo sapiens]
          Length = 380

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 26/98 (26%), Positives = 43/98 (43%), Gaps = 9/98 (9%)

Query: 308 EWYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVFYENKVYNVKIRFLERN 367
           EWY G  +R   E A  +   +G FL+RD  +   +    L    +NK + V        
Sbjct: 284 EWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNKHFKV-------- 335

Query: 368 QQFALGTGLRGDEKFDSVEDIIEHYKNFPIILIDGKDK 405
            Q        G  +F ++++++EHYK  PI   +  +K
Sbjct: 336 -QLVDNVYCIGQRRFHTMDELVEHYKKAPIFTSEHGEK 372


>gi|52630423 NCK adaptor protein 2 isoform A [Homo sapiens]
          Length = 380

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 26/98 (26%), Positives = 43/98 (43%), Gaps = 9/98 (9%)

Query: 308 EWYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVFYENKVYNVKIRFLERN 367
           EWY G  +R   E A  +   +G FL+RD  +   +    L    +NK + V        
Sbjct: 284 EWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNKHFKV-------- 335

Query: 368 QQFALGTGLRGDEKFDSVEDIIEHYKNFPIILIDGKDK 405
            Q        G  +F ++++++EHYK  PI   +  +K
Sbjct: 336 -QLVDNVYCIGQRRFHTMDELVEHYKKAPIFTSEHGEK 372


>gi|33598948 phospholipase C, gamma 1 isoform a [Homo sapiens]
          Length = 1291

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 25/93 (26%), Positives = 49/93 (52%), Gaps = 10/93 (10%)

Query: 305 QHNEWYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVFYENKVYNVKIRFL 364
           +  EWY    +R   E   M+  +DG+FLVR    +++   Y ++   E K+ + +++  
Sbjct: 664 ESKEWYHASLTRAQAEHMLMRVPRDGAFLVR---KRNEPNSYAISFRAEGKIKHCRVQ-- 718

Query: 365 ERNQQFALGTGLRGDEKFDSVEDIIEHYKNFPI 397
           +  Q     T + G+ +FDS+ D+I +Y+  P+
Sbjct: 719 QEGQ-----TVMLGNSEFDSLVDLISYYEKHPL 746



 Score = 33.1 bits (74), Expect = 0.50
 Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 13/94 (13%)

Query: 329 DGSFLVRDCSTKSKEEPYVLAVFYENKVYNVKIRFLERNQQFALGTGLRGDEKFDSVEDI 388
           DGSFLVR+  T   +  Y L+ +   KV + +I    R         L  +  FDS+ D+
Sbjct: 580 DGSFLVRESETFVGD--YTLSFWRNGKVQHCRIH--SRQDAGTPKFFLTDNLVFDSLYDL 635

Query: 389 IEHYKNFPIILIDGKDKTGVHRKQCHLTQPLPLT 422
           I HY+  P+           +  +  L++P+P T
Sbjct: 636 ITHYQQVPL---------RCNEFEMRLSEPVPQT 660


>gi|33598946 phospholipase C, gamma 1 isoform b [Homo sapiens]
          Length = 1290

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 25/93 (26%), Positives = 49/93 (52%), Gaps = 10/93 (10%)

Query: 305 QHNEWYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVFYENKVYNVKIRFL 364
           +  EWY    +R   E   M+  +DG+FLVR    +++   Y ++   E K+ + +++  
Sbjct: 664 ESKEWYHASLTRAQAEHMLMRVPRDGAFLVR---KRNEPNSYAISFRAEGKIKHCRVQ-- 718

Query: 365 ERNQQFALGTGLRGDEKFDSVEDIIEHYKNFPI 397
           +  Q     T + G+ +FDS+ D+I +Y+  P+
Sbjct: 719 QEGQ-----TVMLGNSEFDSLVDLISYYEKHPL 746



 Score = 33.1 bits (74), Expect = 0.50
 Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 13/94 (13%)

Query: 329 DGSFLVRDCSTKSKEEPYVLAVFYENKVYNVKIRFLERNQQFALGTGLRGDEKFDSVEDI 388
           DGSFLVR+  T   +  Y L+ +   KV + +I    R         L  +  FDS+ D+
Sbjct: 580 DGSFLVRESETFVGD--YTLSFWRNGKVQHCRIH--SRQDAGTPKFFLTDNLVFDSLYDL 635

Query: 389 IEHYKNFPIILIDGKDKTGVHRKQCHLTQPLPLT 422
           I HY+  P+           +  +  L++P+P T
Sbjct: 636 ITHYQQVPL---------RCNEFEMRLSEPVPQT 660


>gi|166795247 phosphoinositide-3-kinase, regulatory subunit 3 (p55,
           gamma) [Homo sapiens]
          Length = 461

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 36/109 (33%), Positives = 55/109 (50%), Gaps = 16/109 (14%)

Query: 292 RPPFPKRS----DRKD----VQHNEWYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKE 343
           +PP P  S      KD    +Q  EWY G+ SR+ V +  +++  DG+FLVRD STK + 
Sbjct: 40  KPPKPMTSAVPNGMKDSSVSLQDAEWYWGDISREEVNDK-LRDMPDGTFLVRDASTKMQG 98

Query: 344 EPYVLAVFYENKVYNVKIRFLERNQQFALGTGLRGDEKFDSVEDIIEHY 392
           + Y L +       N  I+   R+ ++     L     F+SV ++I HY
Sbjct: 99  D-YTLTL--RKGGNNKLIKIYHRDGKYGFSDPL----TFNSVVELINHY 140


>gi|166795245 phosphoinositide-3-kinase, regulatory subunit 3 (p55,
           gamma) [Homo sapiens]
          Length = 461

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 36/109 (33%), Positives = 55/109 (50%), Gaps = 16/109 (14%)

Query: 292 RPPFPKRS----DRKD----VQHNEWYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKE 343
           +PP P  S      KD    +Q  EWY G+ SR+ V +  +++  DG+FLVRD STK + 
Sbjct: 40  KPPKPMTSAVPNGMKDSSVSLQDAEWYWGDISREEVNDK-LRDMPDGTFLVRDASTKMQG 98

Query: 344 EPYVLAVFYENKVYNVKIRFLERNQQFALGTGLRGDEKFDSVEDIIEHY 392
           + Y L +       N  I+   R+ ++     L     F+SV ++I HY
Sbjct: 99  D-YTLTL--RKGGNNKLIKIYHRDGKYGFSDPL----TFNSVVELINHY 140


>gi|4885153 v-crk sarcoma virus CT10 oncogene homolog (avian)-like
           [Homo sapiens]
          Length = 303

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 11/96 (11%)

Query: 298 RSDRKDVQHNEWYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVFYENKVY 357
           R D  D   + WY+G  SRQ  +   ++  + G FLVRD ST   +  YVL+V   ++V 
Sbjct: 5   RFDSSD--RSAWYMGPVSRQEAQTR-LQGQRHGMFLVRDSSTCPGD--YVLSVSENSRVS 59

Query: 358 NVKIRFLERNQQFALGTGLRGDEKFDSVEDIIEHYK 393
           +  I  L  N++F +G     D++FD +  ++E YK
Sbjct: 60  HYIINSLP-NRRFKIG-----DQEFDHLPALLEFYK 89


>gi|158631203 dual adaptor of phosphotyrosine and
           3-phosphoinositides [Homo sapiens]
          Length = 280

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 25/90 (27%), Positives = 45/90 (50%), Gaps = 9/90 (10%)

Query: 309 WYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVFYENKVYNVKIRFLERNQ 368
           WY G  +R A E   +    DGS+L+RD  +      Y L+V  ++ V +  + +   + 
Sbjct: 35  WYHGNLTRHAAEALLLSNGCDGSYLLRD--SNETTGLYSLSVRAKDSVKHFHVEYTGYSF 92

Query: 369 QFALGTGLRGDEKFDSVEDIIEHYKNFPII 398
           +F       G  +F S++D ++H+ N P+I
Sbjct: 93  KF-------GFNEFSSLKDFVKHFANQPLI 115


>gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo
           sapiens]
          Length = 1258

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 22/57 (38%), Positives = 31/57 (54%), Gaps = 2/57 (3%)

Query: 305 QHNEWYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVFYENKVYNVKI 361
           Q   WY  + SR A EE   +  +DGSFLVRD  ++S    + L V Y+  V+  +I
Sbjct: 17  QAPSWYHRDLSRAAAEELLARAGRDGSFLVRD--SESVAGAFALCVLYQKHVHTYRI 71


>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
          Length = 1682

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 62/243 (25%), Positives = 85/243 (34%), Gaps = 73/243 (30%)

Query: 71  DPELRMEETWQSIK--ILPARPIKESEYADTHYFKVAMDTPLPLDTR---TSISIGQPTW 125
           D  +R EE  Q  +  + P  P+KE           ++ +P P DT    T+ ++   T 
Sbjct: 703 DESIRKEEEQQQHEAGVAPQPPLKEPF--------ASLQSPFPTDTAPTTTAPAVAVTTT 754

Query: 126 NTQTRLERVDKPISKDVRSQNIKGDASVRKNKIPLPPPRPLITLPKKYQPLPPEPESSRP 185
            T T      +   K              K    LPPP PL   P   QP PP P    P
Sbjct: 755 TTTTTTTTATQEEEK--------------KPPPALPPPPPLAKFPPPSQPQPPPP----P 796

Query: 186 PLSQRHTFPEVQRMPSQISLRDLSEVLEAEK----------------VPHNQRKP----- 224
           P S           P+ + L+ L+ VLE +K                +P  Q  P     
Sbjct: 797 PPS-----------PASL-LKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSG 844

Query: 225 ----ESTHLLENQNTQEIPLAISSSSFTTSNHSVQNRDHRGGMQ----PCSPQRCQPPAS 276
                 T    +      P A SSS F+TS      R+ R G +    P +P +  PP S
Sbjct: 845 ATALPPTSAAPSAQGSPQPSASSSSQFSTSG-GPWARERRAGEEPVPGPMTPTQPPPPLS 903

Query: 277 CSP 279
             P
Sbjct: 904 LPP 906


>gi|4557377 Bruton agammaglobulinemia tyrosine kinase [Homo sapiens]
          Length = 659

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 52/215 (24%), Positives = 80/215 (37%), Gaps = 71/215 (33%)

Query: 143 RSQNIKGDASVRKNKIPLPPPRPLITLPKKYQPLPPEPESSRPPLSQRHTFPEVQRMPSQ 202
           R+ ++K  +S RK K PLPP      + KK  PLPPEP ++                   
Sbjct: 171 RNGSLKPGSSHRKTKKPLPPTPEEDQILKK--PLPPEPAAA------------------P 210

Query: 203 ISLRDLSEVLEA-EKVPHNQ-----RKPESTHLLENQNTQEIPLAISSSSFTTSNHSVQN 256
           +S  +L +V+   + +P N      RK +   +LE  N   +P               + 
Sbjct: 211 VSTSELKKVVALYDYMPMNANDLQLRKGDEYFILEESN---LPWW-------------RA 254

Query: 257 RDHRGGMQPCSPQRCQPPASCSPHENILPYKYTSWRPPFPKRSDRKDVQHNEWYIGEYSR 316
           RD  G                   E  +P  Y +             ++  EWY    +R
Sbjct: 255 RDKNG------------------QEGYIPSNYVT--------EAEDSIEMYEWYSKHMTR 288

Query: 317 QAVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVF 351
              E+   +E K+G F+VRD S   K   Y ++VF
Sbjct: 289 SQAEQLLKQEGKEGGFIVRDSSKAGK---YTVSVF 320


>gi|224586793 src homology 2 domain-containing transforming protein
           C3 [Homo sapiens]
          Length = 594

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 69/287 (24%), Positives = 113/287 (39%), Gaps = 47/287 (16%)

Query: 130 RLERVDKPISKDVRSQNIKGDASVRK--NKIPLPPPRPLITLPKKYQPLPPEPESSRPPL 187
           R++ +D+P +++      +GD S     N IP   P P   L  + +P P  P++++   
Sbjct: 321 RMQSLDEPWTEE------EGDGSDHPYYNSIPSKMPPPGGFLDTRLKPRPHAPDTAQFAG 374

Query: 188 SQ------RH---TFPEV-QRMPSQISLRDLSEVLEAEKVPHNQRKPESTHLLENQNT-- 235
            +      RH   TF E  Q+ P +    D+    E +   H     E+   +  Q    
Sbjct: 375 KEQTYYQGRHLGDTFGEDWQQTPLRQGSSDIYSTPEGKL--HVAPTGEAPTYVNTQQIPP 432

Query: 236 QEIPLAISSSSFTTSNHSVQNRDHRGGM--QPCSPQRCQPPASCSPHENILPYKYTSWRP 293
           Q  P A+SS+  +        +     +  QP  P      +  +  E I P       P
Sbjct: 433 QAWPAAVSSAESSPRKDLFDMKPFEDALKNQPLGPVL----SKAASVECISPVS-----P 483

Query: 294 PFPKRSDRKDVQHNEWYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVFYE 353
             P     +++Q   WY GE SR+  E       KDG FLVR  +T      +VL   + 
Sbjct: 484 RAPDAKMLEELQAETWYQGEMSRKEAEGLL---EKDGDFLVRKSTTNPGS--FVLTGMHN 538

Query: 354 NKVYNVKIRFLERNQQFALGTGLRGDEKFDSVEDIIEHY--KNFPII 398
            +  ++ +   E       GT    D  FDS+  +I H+   + PI+
Sbjct: 539 GQAKHLLLVDPE-------GTIRTKDRVFDSISHLINHHLESSLPIV 578


>gi|150378503 leiomodin 2 (cardiac) [Homo sapiens]
          Length = 547

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 33/130 (25%), Positives = 54/130 (41%), Gaps = 28/130 (21%)

Query: 159 PLPPPRPLITLPKKYQPLPPEPESSRPPLSQRHTFPEVQRMPSQISLRDLSEVLE----A 214
           P PPP P    P   Q LPP P    PPL ++           ++  R+++EV++    A
Sbjct: 421 PPPPPPPPPPPPPSSQRLPPPPPPPPPPLPEK-----------KLITRNIAEVIKQQESA 469

Query: 215 EKVPHNQRKPESTHLLENQNTQEIPLAISSSSFTTSNHSVQNRDHRGGMQPCSPQRCQPP 274
           ++   N +K +    ++ Q    +           S  SVQ +      +P +PQR    
Sbjct: 470 QRALQNGQKKKKGKKVKKQPNSIL------KEIKNSLRSVQEKKMEDSSRPSTPQR---- 519

Query: 275 ASCSPHENIL 284
              S HEN++
Sbjct: 520 ---SAHENLM 526


>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
          Length = 1573

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 44/175 (25%), Positives = 63/175 (36%), Gaps = 35/175 (20%)

Query: 150  DASVRKNKIPLPPPRPLITLPKKY--QPLPPEPESSRPPLSQR----HTFPEVQRMPSQI 203
            D+SV     P P P PL TLPK+    P  P   +S  P S++     T P++   P   
Sbjct: 1075 DSSVVPALTPEPSPTPLPTLPKELTSDPSTPSEVTSLSPTSEQVPESDTTPDLDTTPYSS 1134

Query: 204  SLRDLSEVLEAEKVPHNQRKPESTHLLE-----------------NQNTQEIPLAISSSS 246
            ++ + S   +    PH    P+ T   +                 +  T   P  I+ S+
Sbjct: 1135 TVSEYSRSPDPSPSPHPTTTPDPTMAPDPITTLNPTVTPHFPTTPHPTTTPHPTTITHST 1194

Query: 247  -----------FTTSNHSVQNRDHRGGMQP-CSPQRCQPPASCSPHENILPYKYT 289
                       FTT  HS    D     QP  + Q    P S +PH    P+  T
Sbjct: 1195 MIPDPTTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHSTTPHPTTTPHPTT 1249


>gi|197304715 vav 2 guanine nucleotide exchange factor isoform 1
           [Homo sapiens]
          Length = 878

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 23/103 (22%), Positives = 56/103 (54%), Gaps = 10/103 (9%)

Query: 292 RPPFPKRSDRK-DVQHNEWYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAV 350
           RPP  +   R+ D     W+ G   RQ  +   +K +  G++L+R+    ++ E + +++
Sbjct: 655 RPPISRPPSREIDYTAYPWFAGNMERQQTDN-LLKSHASGTYLIRE--RPAEAERFAISI 711

Query: 351 FYENKVYNVKIRFLERNQQFALGTGLRGDEKFDSVEDIIEHYK 393
            + ++V ++K+  +E++    +       +KFDS+ +++E+Y+
Sbjct: 712 KFNDEVKHIKV--VEKDNWIHITEA----KKFDSLLELVEYYQ 748


>gi|40549448 vav 2 guanine nucleotide exchange factor isoform 2
           [Homo sapiens]
          Length = 839

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 23/103 (22%), Positives = 56/103 (54%), Gaps = 10/103 (9%)

Query: 292 RPPFPKRSDRK-DVQHNEWYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAV 350
           RPP  +   R+ D     W+ G   RQ  +   +K +  G++L+R+    ++ E + +++
Sbjct: 645 RPPISRPPSREIDYTAYPWFAGNMERQQTDN-LLKSHASGTYLIRE--RPAEAERFAISI 701

Query: 351 FYENKVYNVKIRFLERNQQFALGTGLRGDEKFDSVEDIIEHYK 393
            + ++V ++K+  +E++    +       +KFDS+ +++E+Y+
Sbjct: 702 KFNDEVKHIKV--VEKDNWIHITEA----KKFDSLLELVEYYQ 738


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.132    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,200,533
Number of Sequences: 37866
Number of extensions: 1015486
Number of successful extensions: 4855
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 70
Number of HSP's successfully gapped in prelim test: 214
Number of HSP's that attempted gapping in prelim test: 4260
Number of HSP's gapped (non-prelim): 746
length of query: 428
length of database: 18,247,518
effective HSP length: 105
effective length of query: 323
effective length of database: 14,271,588
effective search space: 4609722924
effective search space used: 4609722924
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.