BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|19263349 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 [Homo sapiens] (184 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|19263349 Cbp/p300-interacting transactivator, with Glu/Asp-ri... 387 e-108 gi|222136692 melanocyte-specific gene 1 isoform 1 [Homo sapiens] 74 5e-14 gi|222136690 melanocyte-specific gene 1 isoform 1 [Homo sapiens] 74 5e-14 gi|222136688 melanocyte-specific gene 1 isoform 2 [Homo sapiens] 74 5e-14 gi|222136686 melanocyte-specific gene 1 isoform 1 [Homo sapiens] 74 5e-14 gi|19923343 Cbp/p300-interacting transactivator, with Glu/Asp-ri... 62 2e-10 gi|150417989 cyclin K isoform 1 [Homo sapiens] 62 3e-10 gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 60 8e-10 gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 60 8e-10 gi|110832843 TBP-associated factor 4 [Homo sapiens] 60 1e-09 gi|11386183 WAS protein family, member 2 [Homo sapiens] 59 2e-09 gi|157168329 formin 1 [Homo sapiens] 57 1e-08 gi|7706501 WW domain binding protein 11 [Homo sapiens] 56 2e-08 gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 55 3e-08 gi|33356148 formin-like 1 [Homo sapiens] 55 3e-08 gi|149999378 inverted formin 2 isoform 2 [Homo sapiens] 55 4e-08 gi|149999380 inverted formin 2 isoform 1 [Homo sapiens] 55 4e-08 gi|146134388 YLP motif containing 1 [Homo sapiens] 55 4e-08 gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 55 4e-08 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 54 6e-08 gi|160707881 formin 2 [Homo sapiens] 54 8e-08 gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 54 1e-07 gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 53 1e-07 gi|22027541 programmed cell death 7 [Homo sapiens] 53 2e-07 gi|163965366 nascent polypeptide-associated complex alpha subuni... 52 2e-07 gi|210032580 SET domain containing 1B [Homo sapiens] 52 3e-07 gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 52 4e-07 gi|11386197 forkhead box E3 [Homo sapiens] 52 4e-07 gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 52 4e-07 gi|153792074 proline rich 12 [Homo sapiens] 52 4e-07 >gi|19263349 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 [Homo sapiens] Length = 184 Score = 387 bits (994), Expect = e-108 Identities = 184/184 (100%), Positives = 184/184 (100%) Query: 1 MADHLMLAEGYRLVQRPPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPG 60 MADHLMLAEGYRLVQRPPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPG Sbjct: 1 MADHLMLAEGYRLVQRPPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPG 60 Query: 61 ALAYGAFGPPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAA 120 ALAYGAFGPPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAA Sbjct: 61 ALAYGAFGPPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAA 120 Query: 121 APPPPAHALGGMDAELIDEEALTSLELELGLHRVRELPELFLGQSEFDCFSDLGSAPPAG 180 APPPPAHALGGMDAELIDEEALTSLELELGLHRVRELPELFLGQSEFDCFSDLGSAPPAG Sbjct: 121 APPPPAHALGGMDAELIDEEALTSLELELGLHRVRELPELFLGQSEFDCFSDLGSAPPAG 180 Query: 181 SVSC 184 SVSC Sbjct: 181 SVSC 184 >gi|222136692 melanocyte-specific gene 1 isoform 1 [Homo sapiens] Length = 193 Score = 74.3 bits (181), Expect = 5e-14 Identities = 61/171 (35%), Positives = 77/171 (45%), Gaps = 32/171 (18%) Query: 19 SAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPA 78 + A H P +G S P G+P PP + P SF PA Sbjct: 41 AVAILHYPGVASNGTKASGAPTSSSGSPIGSPTTTPPTKPP------------SFNLHPA 88 Query: 79 VPPPAAGIAHLQPVATPYPGRAAAPPNAPG--GPP-----GPQP------APSAAAPPPP 125 P HLQ + + Y G AAA P PG GP G Q +PSA A P Sbjct: 89 --PHLLASMHLQKLNSQYQGMAAATPGQPGEAGPLQNWDFGAQAGGAESLSPSAGAQSPA 146 Query: 126 AHALGGMDAELIDEEALTSLELELGLHRVRELPELFLGQSEFDCFSDLGSA 176 +D++ +DEE L SL +ELGL R ELPEL+LGQ+EFD +D S+ Sbjct: 147 I-----IDSDPVDEEVLMSLVVELGLDRANELPELWLGQNEFDFTADFPSS 192 >gi|222136690 melanocyte-specific gene 1 isoform 1 [Homo sapiens] Length = 193 Score = 74.3 bits (181), Expect = 5e-14 Identities = 61/171 (35%), Positives = 77/171 (45%), Gaps = 32/171 (18%) Query: 19 SAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPA 78 + A H P +G S P G+P PP + P SF PA Sbjct: 41 AVAILHYPGVASNGTKASGAPTSSSGSPIGSPTTTPPTKPP------------SFNLHPA 88 Query: 79 VPPPAAGIAHLQPVATPYPGRAAAPPNAPG--GPP-----GPQP------APSAAAPPPP 125 P HLQ + + Y G AAA P PG GP G Q +PSA A P Sbjct: 89 --PHLLASMHLQKLNSQYQGMAAATPGQPGEAGPLQNWDFGAQAGGAESLSPSAGAQSPA 146 Query: 126 AHALGGMDAELIDEEALTSLELELGLHRVRELPELFLGQSEFDCFSDLGSA 176 +D++ +DEE L SL +ELGL R ELPEL+LGQ+EFD +D S+ Sbjct: 147 I-----IDSDPVDEEVLMSLVVELGLDRANELPELWLGQNEFDFTADFPSS 192 >gi|222136688 melanocyte-specific gene 1 isoform 2 [Homo sapiens] Length = 219 Score = 74.3 bits (181), Expect = 5e-14 Identities = 61/171 (35%), Positives = 77/171 (45%), Gaps = 32/171 (18%) Query: 19 SAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPA 78 + A H P +G S P G+P PP + P SF PA Sbjct: 67 AVAILHYPGVASNGTKASGAPTSSSGSPIGSPTTTPPTKPP------------SFNLHPA 114 Query: 79 VPPPAAGIAHLQPVATPYPGRAAAPPNAPG--GPP-----GPQP------APSAAAPPPP 125 P HLQ + + Y G AAA P PG GP G Q +PSA A P Sbjct: 115 --PHLLASMHLQKLNSQYQGMAAATPGQPGEAGPLQNWDFGAQAGGAESLSPSAGAQSPA 172 Query: 126 AHALGGMDAELIDEEALTSLELELGLHRVRELPELFLGQSEFDCFSDLGSA 176 +D++ +DEE L SL +ELGL R ELPEL+LGQ+EFD +D S+ Sbjct: 173 I-----IDSDPVDEEVLMSLVVELGLDRANELPELWLGQNEFDFTADFPSS 218 >gi|222136686 melanocyte-specific gene 1 isoform 1 [Homo sapiens] Length = 193 Score = 74.3 bits (181), Expect = 5e-14 Identities = 61/171 (35%), Positives = 77/171 (45%), Gaps = 32/171 (18%) Query: 19 SAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPA 78 + A H P +G S P G+P PP + P SF PA Sbjct: 41 AVAILHYPGVASNGTKASGAPTSSSGSPIGSPTTTPPTKPP------------SFNLHPA 88 Query: 79 VPPPAAGIAHLQPVATPYPGRAAAPPNAPG--GPP-----GPQP------APSAAAPPPP 125 P HLQ + + Y G AAA P PG GP G Q +PSA A P Sbjct: 89 --PHLLASMHLQKLNSQYQGMAAATPGQPGEAGPLQNWDFGAQAGGAESLSPSAGAQSPA 146 Query: 126 AHALGGMDAELIDEEALTSLELELGLHRVRELPELFLGQSEFDCFSDLGSA 176 +D++ +DEE L SL +ELGL R ELPEL+LGQ+EFD +D S+ Sbjct: 147 I-----IDSDPVDEEVLMSLVVELGLDRANELPELWLGQNEFDFTADFPSS 192 >gi|19923343 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 [Homo sapiens] Length = 270 Score = 62.4 bits (150), Expect = 2e-10 Identities = 35/87 (40%), Positives = 45/87 (51%) Query: 98 GRAAAPPNAPGGPPGPQPAPSAAAPPPPAHALGGMDAELIDEEALTSLELELGLHRVREL 157 G A N+ GG S A P +D + IDEE L SL +E+GL R++EL Sbjct: 184 GGGAGSSNSGGGSGSGNMPASVAHVPAAMLPPNVIDTDFIDEEVLMSLVIEMGLDRIKEL 243 Query: 158 PELFLGQSEFDCFSDLGSAPPAGSVSC 184 PEL+LGQ+EFD +D VSC Sbjct: 244 PELWLGQNEFDFMTDFVCKQQPSRVSC 270 >gi|150417989 cyclin K isoform 1 [Homo sapiens] Length = 580 Score = 62.0 bits (149), Expect = 3e-10 Identities = 49/148 (33%), Positives = 57/148 (38%), Gaps = 34/148 (22%) Query: 6 MLAEGYRLVQRPPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYG 65 M EGY+ +Q S GP + LPP GP P P PPPP P Sbjct: 439 MSGEGYQSLQ---SMMKTEGP-SYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPP----- 489 Query: 66 AFGPPSSFQPFPAVPPPAAGIAHLQPVATP--------YPGRAAAPPNAPGG-------- 109 PP+SF P PA+PPP G P P P A PP+ P G Sbjct: 490 ---PPASFPP-PAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASY 545 Query: 110 -----PPGPQPAPSAAAPPPPAHALGGM 132 PPG QP PPP +GG+ Sbjct: 546 PPPAVPPGGQPPVPPPIPPPGMPPVGGL 573 Score = 45.1 bits (105), Expect = 4e-05 Identities = 37/124 (29%), Positives = 48/124 (38%), Gaps = 16/124 (12%) Query: 13 LVQRPPSAAAAHGPHALRTLPPY-AGPG---LDSGLRPRGAPLGPPPPRQPGALAYGAFG 68 L RPP + + T Y +G G L S ++ G G PP A+G Sbjct: 416 LPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPP---------AYG 466 Query: 69 PPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAAAPP---PP 125 PP+ P V PP + P +P A PP PP P P+ PP PP Sbjct: 467 PPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPP 526 Query: 126 AHAL 129 HA+ Sbjct: 527 THAV 530 Score = 40.8 bits (94), Expect = 7e-04 Identities = 28/84 (33%), Positives = 34/84 (40%), Gaps = 5/84 (5%) Query: 53 PPPPRQPGALAYGAFGPPSSFQPFPAVPPPAAGIAHLQPV----ATPYPGRAAAPPNAPG 108 PPPP+ P PP+ P PP AA + +P AT P PP P Sbjct: 350 PPPPKIPKIETTHPPLPPAHPPP-DRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPA 408 Query: 109 GPPGPQPAPSAAAPPPPAHALGGM 132 P P P PPPP+ + GM Sbjct: 409 PVHQPPPLPHRPPPPPPSSYMTGM 432 Score = 26.9 bits (58), Expect = 9.9 Identities = 19/52 (36%), Positives = 21/52 (40%), Gaps = 3/52 (5%) Query: 17 PPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFG 68 P A H P L LPP + P + P G P PPP PG G G Sbjct: 526 PTHAVPPHPPPGLG-LPPASYP--PPAVPPGGQPPVPPPIPPPGMPPVGGLG 574 >gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] Length = 1263 Score = 60.5 bits (145), Expect = 8e-10 Identities = 46/133 (34%), Positives = 52/133 (39%), Gaps = 19/133 (14%) Query: 14 VQRPPSAAAAHGPHALRTLPPYAG-------PGLDSGL---RPRGAPLG---PPPPRQPG 60 + PPS G A+ PP +G P L G+ P P G PPPP PG Sbjct: 618 ISSPPSLP---GGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPG 674 Query: 61 ALAYGAFGPP-SSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAP--GGPPGPQPAP 117 + PP P PPP G A + P P PG PP P GGP P P P Sbjct: 675 SARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPP 734 Query: 118 SAAAPPPPAHALG 130 PPPP G Sbjct: 735 GMGMPPPPPFGFG 747 Score = 55.5 bits (132), Expect = 3e-08 Identities = 43/122 (35%), Positives = 47/122 (38%), Gaps = 23/122 (18%) Query: 33 PPYAGPGLDSGL-------RPRGAPLGPPPPRQ-------PGALAYGAFGP-PSSFQPFP 77 PP P L G+ P G + PPPP P L G P PSS Sbjct: 605 PPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGT 664 Query: 78 AVPPPAA--GIAHLQPVATPYPGRAAAPPNAP------GGPPGPQPAPSAAAPPPPAHAL 129 A+PPP G A + P P PG A PP P G PP P P P PPP Sbjct: 665 AIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFP 724 Query: 130 GG 131 GG Sbjct: 725 GG 726 Score = 54.3 bits (129), Expect = 6e-08 Identities = 38/115 (33%), Positives = 44/115 (38%), Gaps = 16/115 (13%) Query: 32 LPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYG---------AFGPPSSFQPFPAVPPP 82 +PP PG DS P P PPPP PG + A PP +PPP Sbjct: 587 IPPPPAPG-DSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPP 645 Query: 83 ---AAGIAHLQPVATPYPGRAAAPPNAPGG---PPGPQPAPSAAAPPPPAHALGG 131 G+ P + P PP PG PP P P P +A PPP L G Sbjct: 646 PPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPG 700 Score = 43.1 bits (100), Expect = 1e-04 Identities = 28/82 (34%), Positives = 33/82 (40%), Gaps = 14/82 (17%) Query: 50 PLGPPPPRQPGALAYGAFGPPSSFQPFPAVPPPAAGIAHLQPVATPYPGRA--AAPPNAP 107 P PP P G + P S P P PPP P P PG ++PP+ P Sbjct: 574 PPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPP--------PPPPPLPGGVCISSPPSLP 625 Query: 108 GG----PPGPQPAPSAAAPPPP 125 GG PP P + PPPP Sbjct: 626 GGTAISPPPPLSGDATIPPPPP 647 Score = 37.0 bits (84), Expect = 0.010 Identities = 25/73 (34%), Positives = 29/73 (39%), Gaps = 17/73 (23%) Query: 69 PPS--SFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAP--------- 117 PPS S P P PP + P P PG + PP P PP P P P Sbjct: 564 PPSVPSRAPVPPAPPLPGDSGTIIP-PPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPP 622 Query: 118 -----SAAAPPPP 125 +A +PPPP Sbjct: 623 SLPGGTAISPPPP 635 Score = 35.0 bits (79), Expect = 0.036 Identities = 23/57 (40%), Positives = 26/57 (45%), Gaps = 6/57 (10%) Query: 79 VPPPAAGIAHLQPVATPYPGRAAA---PPNAPGGPPGPQPAPSAAAPPPPAHALGGM 132 VPP A + P A P PG + PP APG P P P PPPP GG+ Sbjct: 563 VPPSVPSRAPVPP-APPLPGDSGTIIPPPPAPGDSTTPPPPPP--PPPPPPPLPGGV 616 >gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] Length = 1272 Score = 60.5 bits (145), Expect = 8e-10 Identities = 46/133 (34%), Positives = 52/133 (39%), Gaps = 19/133 (14%) Query: 14 VQRPPSAAAAHGPHALRTLPPYAG-------PGLDSGL---RPRGAPLG---PPPPRQPG 60 + PPS G A+ PP +G P L G+ P P G PPPP PG Sbjct: 627 ISSPPSLP---GGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPG 683 Query: 61 ALAYGAFGPP-SSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAP--GGPPGPQPAP 117 + PP P PPP G A + P P PG PP P GGP P P P Sbjct: 684 SARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPP 743 Query: 118 SAAAPPPPAHALG 130 PPPP G Sbjct: 744 GMGMPPPPPFGFG 756 Score = 55.5 bits (132), Expect = 3e-08 Identities = 43/122 (35%), Positives = 47/122 (38%), Gaps = 23/122 (18%) Query: 33 PPYAGPGLDSGL-------RPRGAPLGPPPPRQ-------PGALAYGAFGP-PSSFQPFP 77 PP P L G+ P G + PPPP P L G P PSS Sbjct: 614 PPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGT 673 Query: 78 AVPPPAA--GIAHLQPVATPYPGRAAAPPNAP------GGPPGPQPAPSAAAPPPPAHAL 129 A+PPP G A + P P PG A PP P G PP P P P PPP Sbjct: 674 AIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFP 733 Query: 130 GG 131 GG Sbjct: 734 GG 735 Score = 54.3 bits (129), Expect = 6e-08 Identities = 38/115 (33%), Positives = 44/115 (38%), Gaps = 16/115 (13%) Query: 32 LPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYG---------AFGPPSSFQPFPAVPPP 82 +PP PG DS P P PPPP PG + A PP +PPP Sbjct: 596 IPPPPAPG-DSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPP 654 Query: 83 ---AAGIAHLQPVATPYPGRAAAPPNAPGG---PPGPQPAPSAAAPPPPAHALGG 131 G+ P + P PP PG PP P P P +A PPP L G Sbjct: 655 PPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPG 709 Score = 43.1 bits (100), Expect = 1e-04 Identities = 28/82 (34%), Positives = 33/82 (40%), Gaps = 14/82 (17%) Query: 50 PLGPPPPRQPGALAYGAFGPPSSFQPFPAVPPPAAGIAHLQPVATPYPGRA--AAPPNAP 107 P PP P G + P S P P PPP P P PG ++PP+ P Sbjct: 583 PPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPP--------PPPPPLPGGVCISSPPSLP 634 Query: 108 GG----PPGPQPAPSAAAPPPP 125 GG PP P + PPPP Sbjct: 635 GGTAISPPPPLSGDATIPPPPP 656 Score = 37.0 bits (84), Expect = 0.010 Identities = 25/73 (34%), Positives = 29/73 (39%), Gaps = 17/73 (23%) Query: 69 PPS--SFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAP--------- 117 PPS S P P PP + P P PG + PP P PP P P P Sbjct: 573 PPSVPSRAPVPPAPPLPGDSGTIIP-PPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPP 631 Query: 118 -----SAAAPPPP 125 +A +PPPP Sbjct: 632 SLPGGTAISPPPP 644 Score = 35.0 bits (79), Expect = 0.036 Identities = 23/57 (40%), Positives = 26/57 (45%), Gaps = 6/57 (10%) Query: 79 VPPPAAGIAHLQPVATPYPGRAAA---PPNAPGGPPGPQPAPSAAAPPPPAHALGGM 132 VPP A + P A P PG + PP APG P P P PPPP GG+ Sbjct: 572 VPPSVPSRAPVPP-APPLPGDSGTIIPPPPAPGDSTTPPPPPP--PPPPPPPLPGGV 625 >gi|110832843 TBP-associated factor 4 [Homo sapiens] Length = 1085 Score = 59.7 bits (143), Expect = 1e-09 Identities = 42/110 (38%), Positives = 46/110 (41%), Gaps = 6/110 (5%) Query: 13 LVQRPPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSS 72 ++Q PP AA P PP A + P AP PPPP P LA P Sbjct: 237 VIQTPPFVGAAAPPAPAAPSPPAA----PAPAAPAAAP--PPPPPAPATLARPPGHPAGP 290 Query: 73 FQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAAAP 122 PAVPPPAA A P P AA P G PGP A +A AP Sbjct: 291 PTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAP 340 Score = 54.3 bits (129), Expect = 6e-08 Identities = 40/120 (33%), Positives = 45/120 (37%), Gaps = 9/120 (7%) Query: 17 PPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAY-----GAFGPPS 71 P +A +G AL A P + A L P P PG + GA PP+ Sbjct: 192 PGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPA 251 Query: 72 SFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAAAPPPPAHALGG 131 P P P A A P P P A PP P GPP P A PPP A GG Sbjct: 252 PAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAP----AVPPPAAAQNGG 307 Score = 51.6 bits (122), Expect = 4e-07 Identities = 46/131 (35%), Positives = 52/131 (39%), Gaps = 26/131 (19%) Query: 18 PSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGAL-----------AYGA 66 P+ A P L AGPG G P P GP P PGA ++ A Sbjct: 152 PAPAGPAKPAGPAALAARAGPGPGPGPGPGPGP-GPGKPAGPGAAQTLNGSAALLNSHHA 210 Query: 67 FGP--------PSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAP-PNAPGGPPGPQPAP 117 P P++ P P P A G P P+ G AA P P AP P P PA Sbjct: 211 AAPAVSLVNNGPAALLPLPK--PAAPGTVIQTP---PFVGAAAPPAPAAPSPPAAPAPAA 265 Query: 118 SAAAPPPPAHA 128 AAAPPPP A Sbjct: 266 PAAAPPPPPPA 276 Score = 50.1 bits (118), Expect = 1e-06 Identities = 52/155 (33%), Positives = 57/155 (36%), Gaps = 22/155 (14%) Query: 8 AEGYRLVQRPPSAAAAHGPHALRTLPPYAGPGLDSGLRPR---GAPL--GPPPPRQPGAL 62 A G +V P+ AA GP A P A P R R G P GPP PR+P Sbjct: 57 ALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVP 116 Query: 63 AYGAFGPPSSFQPFP------AVPPPAAGIAHLQPVATPY-------PGRAAA---PPNA 106 A G P + +P P P PAA P P P AA P Sbjct: 117 A-GPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPG 175 Query: 107 PGGPPGPQPAPSAAAPPPPAHALGGMDAELIDEEA 141 PG PGP P P A P A L G A L A Sbjct: 176 PGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHA 210 Score = 28.1 bits (61), Expect = 4.5 Identities = 32/83 (38%), Positives = 33/83 (39%), Gaps = 10/83 (12%) Query: 56 PRQPG--ALAYGAFGPPS-SFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGP-- 110 PR P A A GA G S P A A A P A P P A GGP Sbjct: 45 PRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQR 104 Query: 111 PGPQPAPS----AAAPPPPAHAL 129 PGP P+P A P PPA L Sbjct: 105 PGP-PSPRRPLVPAGPAPPAAKL 126 >gi|11386183 WAS protein family, member 2 [Homo sapiens] Length = 498 Score = 58.9 bits (141), Expect = 2e-09 Identities = 47/130 (36%), Positives = 53/130 (40%), Gaps = 22/130 (16%) Query: 15 QRPPSAAAAHGPHALRTLPPYAGP-GLDSGLRPRGAPLGPPPPR-----QPGALAYGAFG 68 +R + +H P A PP P G G P AP PPPP P + +G+ G Sbjct: 290 KRSSVVSPSHPPPA----PPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPG 345 Query: 69 ---PPS--SFQPFPAV-------PPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPA 116 PPS SF P P PPPAA L P P A PP P PPGP P Sbjct: 346 TPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPP 405 Query: 117 PSAAAPPPPA 126 P A PA Sbjct: 406 PFTGADGQPA 415 Score = 46.2 bits (108), Expect = 2e-05 Identities = 35/97 (36%), Positives = 39/97 (40%), Gaps = 15/97 (15%) Query: 36 AGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPAVPPPAAGIAHLQPVATP 95 AGP S + P P PP PG P F P PA PPP + + P P Sbjct: 287 AGPKRSSVVSPSHPPPAPPLGSPPG--------PKPGFAPPPAPPPPPPPMIGIPPPPPP 338 Query: 96 Y----PGRAAAPPNAPGGPPGPQPAPSAAAPPPPAHA 128 PG PP+ P PP P A A PPPP A Sbjct: 339 VGFGSPG-TPPPPSPPSFPPHPDFA--APPPPPPPPA 372 Score = 44.3 bits (103), Expect = 6e-05 Identities = 43/154 (27%), Positives = 51/154 (33%), Gaps = 24/154 (15%) Query: 17 PPSAAAAHGPHALRTLPP-----YAGPGLDSGLRPRGAP-----LGPPPPRQPGALAYGA 66 PP A P + PP + PG P P PPPP P A Y Sbjct: 318 PPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPT 377 Query: 67 FGPPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAP-PNAPGGPPGPQPAPSAAAPPPP 125 PP QP PPP P P PG P A G P P P P Sbjct: 378 LPPPPLSQPTGGAPPP--------PPPPPPPGPPPPPFTGADGQPAIPPPLSDTTKPKSS 429 Query: 126 AHALGGMDAELIDEEALTSLELELGLHRVRELPE 159 A+ ++L L+++ L RV E E Sbjct: 430 LPAVSDARSDL-----LSAIRQGFQLRRVEEQRE 458 Score = 43.5 bits (101), Expect = 1e-04 Identities = 33/93 (35%), Positives = 41/93 (44%), Gaps = 23/93 (24%) Query: 53 PPPPRQPGALAYGAFGPPSSFQPFPAVPPPA-----------AGIAHLQPVATPYPGRAA 101 PPPP+ A + P SF PPPA +G+A + + P Sbjct: 247 PPPPQSDSASS-----PSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSH-- 299 Query: 102 APPNAP--GGPPGPQP--APSAAAPPPPAHALG 130 PP AP G PPGP+P AP A PPPP +G Sbjct: 300 -PPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIG 331 Score = 37.4 bits (85), Expect = 0.007 Identities = 34/114 (29%), Positives = 44/114 (38%), Gaps = 22/114 (19%) Query: 17 PPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPF 76 PP + +A P P ++ + L P A P Q G+ G GP S Sbjct: 249 PPQSDSASSPS-----PSFS----EDNLPPPPAEFSYPVDNQRGS---GLAGPKRSSVVS 296 Query: 77 PAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAAAPPPPAHALG 130 P+ PPPA + + P P APP AP P P P PPP +G Sbjct: 297 PSHPPPAPPLG-----SPPGPKPGFAPPPAP-----PPPPPPMIGIPPPPPPVG 340 >gi|157168329 formin 1 [Homo sapiens] Length = 1196 Score = 56.6 bits (135), Expect = 1e-08 Identities = 44/116 (37%), Positives = 49/116 (42%), Gaps = 28/116 (24%) Query: 17 PPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPF 76 PP G +L PP P + +G PL PPPP P PPSS P Sbjct: 653 PPPPPLPSGLGSLSPAPPM--PPVSAG-----PPLPPPPPPPP------PLPPPSSAGPP 699 Query: 77 PAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAAAPPPPAHALGGM 132 P PPP P P + APPN PGGPP P P P APPPP G+ Sbjct: 700 PPPPPP------------PLPN-SPAPPN-PGGPP-PAPPPPGLAPPPPPGLFFGL 740 Score = 55.5 bits (132), Expect = 3e-08 Identities = 39/100 (39%), Positives = 46/100 (46%), Gaps = 11/100 (11%) Query: 31 TLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPAVPPPAAGIAHLQ 90 ++PP P L SGL L P PP P + PP P P +PPP++ Sbjct: 651 SIPP--PPPLPSGL----GSLSPAPPMPPVSAGPPLPPPPP---PPPPLPPPSSAGPPPP 701 Query: 91 PVATPYPGRAAAPPNAPGGPPGPQPAPSAAAPPPPAHALG 130 P P P + APPN PGGPP P P A PPPP G Sbjct: 702 PPPPPLP-NSPAPPN-PGGPPPAPPPPGLAPPPPPGLFFG 739 Score = 42.7 bits (99), Expect = 2e-04 Identities = 26/59 (44%), Positives = 30/59 (50%), Gaps = 12/59 (20%) Query: 78 AVPPPAA----------GIAHLQPVATPYPGRAAAPP-NAPGGPPGPQPAPSAAAPPPP 125 A+PPP A G+ L P A P P +A PP P PP P P PS+A PPPP Sbjct: 644 ALPPPPASIPPPPPLPSGLGSLSP-APPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPP 701 Score = 42.7 bits (99), Expect = 2e-04 Identities = 27/60 (45%), Positives = 33/60 (55%), Gaps = 7/60 (11%) Query: 69 PPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQ-PAPSAA--APPPP 125 PP+S P P +P +G+ L P A P P +A PP P PP P P PS+A PPPP Sbjct: 648 PPASIPPPPPLP---SGLGSLSP-APPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPP 703 >gi|7706501 WW domain binding protein 11 [Homo sapiens] Length = 641 Score = 56.2 bits (134), Expect = 2e-08 Identities = 37/93 (39%), Positives = 39/93 (41%), Gaps = 14/93 (15%) Query: 33 PPYAGPGLDSGLRPRGAPLGPPPPRQPGALAY-GAFGPPSSFQPFPAVPPPAAGIAHLQP 91 PP GP LRP G P G PP PGA + G P P P + PP Sbjct: 410 PPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPG-------- 461 Query: 92 VATPYPGRAAAPPNAPGGPPGPQPAPSAAAPPP 124 P PGR PP PG PPG P P PPP Sbjct: 462 ---PPPGRPPGPP--PGPPPGLPPGPPPRGPPP 489 Score = 56.2 bits (134), Expect = 2e-08 Identities = 43/111 (38%), Positives = 48/111 (43%), Gaps = 17/111 (15%) Query: 16 RPPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQP 75 RPP GP R LPP PG RP G P GPPP PG G PP P Sbjct: 443 RPPGMPGLRGPLP-RLLPPGPPPG-----RPPGPPPGPPPGLPPGPPPRG---PPPRLPP 493 Query: 76 F--PAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAAAPPP 124 P +PPP G+ ++P P G APP PP P P P + PP Sbjct: 494 PAPPGIPPPRPGM--MRPPLVPPLG--PAPPGL--FPPAPLPNPGVLSAPP 538 Score = 36.6 bits (83), Expect = 0.013 Identities = 38/117 (32%), Positives = 43/117 (36%), Gaps = 31/117 (26%) Query: 15 QRPPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPP--PRQPGALAYGAFGPPSS 72 Q PP + P + PP GP PLGPPP P +P GPP+ Sbjct: 391 QAPPQSV----PPSQIQAPPMPGP----------PPLGPPPAPPLRPP-------GPPTG 429 Query: 73 FQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAAAPPPPAHAL 129 P P PP A L+P P G P PPGP P PP P L Sbjct: 430 LPPGP---PPGAP-PFLRPPGMP--GLRGPLPRLL--PPGPPPGRPPGPPPGPPPGL 478 Score = 35.4 bits (80), Expect = 0.028 Identities = 24/63 (38%), Positives = 24/63 (38%), Gaps = 3/63 (4%) Query: 69 PPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAAAPPPPAHA 128 PP S P PP G L P P P R PP G PPGP P PP Sbjct: 393 PPQSVPPSQIQAPPMPGPPPLGPPPAP-PLRPPGPPT--GLPPGPPPGAPPFLRPPGMPG 449 Query: 129 LGG 131 L G Sbjct: 450 LRG 452 Score = 32.0 bits (71), Expect = 0.31 Identities = 20/49 (40%), Positives = 27/49 (55%), Gaps = 7/49 (14%) Query: 16 RPPSA---AAAHGP--HALRTLP--PYAGPGLDSGLRPRGAPLGPPPPR 57 +PPS +A+GP A+ LP + P L G +P G P GPPPP+ Sbjct: 162 QPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPPPQ 210 Score = 28.9 bits (63), Expect = 2.6 Identities = 19/50 (38%), Positives = 22/50 (44%), Gaps = 6/50 (12%) Query: 69 PPSSFQPFPAVPPPAAGIAHL----QPVATPYPGRAAAPPNAPGGPPGPQ 114 PPS + A PP ++ L V PGR PP P GPP PQ Sbjct: 163 PPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRK--PPGPPPGPPPPQ 210 >gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sapiens] Length = 505 Score = 55.1 bits (131), Expect = 3e-08 Identities = 46/119 (38%), Positives = 52/119 (43%), Gaps = 28/119 (23%) Query: 17 PPSAAAAHGPHALRTLPPYAGPGLDSGLRP-----RGAPLGPPPPRQPGALAYGAFGPPS 71 PP + GP PP P +SG P RGAP PPP R P A A PP Sbjct: 278 PPPPPSRGGP------PPPPPPPHNSGPPPPPARGRGAP-PPPPSRAPTA----APPPPP 326 Query: 72 SFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPA-----PSAAAPPPP 125 +P AVPPP + P P A P +AP GPP P P+ P A PPPP Sbjct: 327 PSRPSVAVPPPPPN--RMYPPPPP-----ALPSSAPSGPPPPPPSVLGVGPVAPPPPPP 378 Score = 45.4 bits (106), Expect = 3e-05 Identities = 39/123 (31%), Positives = 46/123 (37%), Gaps = 23/123 (18%) Query: 17 PPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPF 76 PPS A P A PP + P + P PPPP P + G Sbjct: 313 PPSRA----PTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGP---------- 358 Query: 77 PAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAAAPPPPAHALGGMDAEL 136 PPP + + PVA P P PP P GPP P PS P A G A L Sbjct: 359 ---PPPPPSVLGVGPVAPPPP----PPPPPPPGPPPPPGLPSDGDHQVPTTA--GNKAAL 409 Query: 137 IDE 139 +D+ Sbjct: 410 LDQ 412 Score = 37.0 bits (84), Expect = 0.010 Identities = 23/54 (42%), Positives = 26/54 (48%), Gaps = 9/54 (16%) Query: 77 PAVPPPAAGIAHLQPVATPYPGRAAAPPNAP--G---GPPGPQPAPSAAAPPPP 125 P PPP+ G P P P + PP P G PP P AP+AA PPPP Sbjct: 277 PPPPPPSRG----GPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPP 326 Score = 35.8 bits (81), Expect = 0.021 Identities = 16/29 (55%), Positives = 17/29 (58%), Gaps = 2/29 (6%) Query: 99 RAAAPPNAP--GGPPGPQPAPSAAAPPPP 125 R A PP P GGPP P P P + PPPP Sbjct: 274 RQAPPPPPPSRGGPPPPPPPPHNSGPPPP 302 Score = 33.5 bits (75), Expect = 0.11 Identities = 13/28 (46%), Positives = 16/28 (57%) Query: 103 PPNAPGGPPGPQPAPSAAAPPPPAHALG 130 PP+ G PP P P ++ PPPPA G Sbjct: 281 PPSRGGPPPPPPPPHNSGPPPPPARGRG 308 Score = 32.7 bits (73), Expect = 0.18 Identities = 16/38 (42%), Positives = 17/38 (44%), Gaps = 4/38 (10%) Query: 95 PYPGRAAAPPNAP----GGPPGPQPAPSAAAPPPPAHA 128 P P R PP P GPP P A PPPP+ A Sbjct: 280 PPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRA 317 >gi|33356148 formin-like 1 [Homo sapiens] Length = 1100 Score = 55.1 bits (131), Expect = 3e-08 Identities = 41/105 (39%), Positives = 43/105 (40%), Gaps = 12/105 (11%) Query: 38 PGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPAVPPPAAGIAHLQPVATPYP 97 P L P PPPP PG L PPS+ P PP G P A P P Sbjct: 528 PDLAPAAEPAPGAAPPPPPPLPG-LPSPQEAPPSA----PPQAPPLPGSPE-PPPAPPLP 581 Query: 98 GRAAAPPNAPGGPP---GPQPAPSAAAPPPPA---HALGGMDAEL 136 G PP P PP GP P P PPPP ALG D+EL Sbjct: 582 GDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPPDALGRRDSEL 626 Score = 45.1 bits (105), Expect = 4e-05 Identities = 31/86 (36%), Positives = 32/86 (37%), Gaps = 8/86 (9%) Query: 48 GAPLGPPPPRQPGAL--AYGAFGPPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPN 105 G P G P P A A GA PP P P +P P P A P PG PP Sbjct: 520 GVPTGSPSPDLAPAAEPAPGAAPPPPP--PLPGLPSPQEAPPSAPPQAPPLPGSPEPPP- 576 Query: 106 APGGPPGPQPAPSAAAPPPPAHALGG 131 PP P P PPPP G Sbjct: 577 ---APPLPGDLPPPPPPPPPPPGTDG 599 Score = 43.5 bits (101), Expect = 1e-04 Identities = 48/156 (30%), Positives = 56/156 (35%), Gaps = 34/156 (21%) Query: 17 PPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPP--PRQPGALAYGAFGP-PSSF 73 P A AA PP PGL S P+ AP PP P PG+ P P Sbjct: 528 PDLAPAAEPAPGAAPPPPPPLPGLPS---PQEAPPSAPPQAPPLPGSPEPPPAPPLPGDL 584 Query: 74 QPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPP------GPQPAPSAAAPPP--- 124 P P PPP G PV P P PP PGGPP + P A P Sbjct: 585 PPPPPPPPPPPGTD--GPVPPPPP----PPPPPPGGPPDALGRRDSELGPGVKAKKPIQT 638 Query: 125 -------------PAHALGGMDAELIDEEALTSLEL 147 P+ G + EL DE+ L L++ Sbjct: 639 KFRMPLLNWVALKPSQITGTVFTELNDEKVLQELDM 674 Score = 37.0 bits (84), Expect = 0.010 Identities = 22/52 (42%), Positives = 24/52 (46%), Gaps = 7/52 (13%) Query: 81 PPAAGIAHLQPVATPYPGRAAAP-PNAPGGPPGP------QPAPSAAAPPPP 125 P A + PVA P AP P P G P P +PAP AA PPPP Sbjct: 495 PGDAVSIEILPVAVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPP 546 Score = 30.0 bits (66), Expect = 1.2 Identities = 27/79 (34%), Positives = 29/79 (36%), Gaps = 23/79 (29%) Query: 69 PPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGP------PGPQPAPSAAAP 122 P P P VP + L P A P PG A P P P PQ AP +A P Sbjct: 511 PSGGDAPTPGVPTGSPS-PDLAPAAEPAPGAA------PPPPPPLPGLPSPQEAPPSAPP 563 Query: 123 ----------PPPAHALGG 131 PPPA L G Sbjct: 564 QAPPLPGSPEPPPAPPLPG 582 Score = 27.3 bits (59), Expect = 7.6 Identities = 17/51 (33%), Positives = 18/51 (35%) Query: 78 AVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAAAPPPPAHA 128 AV P+ G A V T P AP P P P P P P A Sbjct: 507 AVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEA 557 >gi|149999378 inverted formin 2 isoform 2 [Homo sapiens] Length = 1240 Score = 54.7 bits (130), Expect = 4e-08 Identities = 40/113 (35%), Positives = 47/113 (41%), Gaps = 20/113 (17%) Query: 33 PPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPAVPPPAAGIAH-LQP 91 PP P L S + + P PPPP PG GA PP+ P +PPP G L P Sbjct: 439 PPPPPPPLPS-VGAKALPTAPPPPPLPG---LGAMAPPA-----PPLPPPLPGSCEFLPP 489 Query: 92 VATPYPGRAAAPPNAP-------GGPPGPQPAPSAAAPPPPAHALGGMDAELI 137 P PG PP P G PP P P PP A GGM+ ++ Sbjct: 490 PPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLLPCTCSPPVA---GGMEEVIV 539 Score = 52.4 bits (124), Expect = 2e-07 Identities = 37/111 (33%), Positives = 43/111 (38%), Gaps = 15/111 (13%) Query: 26 PHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPAVPPPAAG 85 P AL P L P + PPPP P + GA P++ PPP G Sbjct: 411 PRALEQQASTPPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTA-----PPPPPLPG 465 Query: 86 IAHLQPVATPYPGRAAAPPNAPGG----PPGPQPAPSAAAPPPPAHALGGM 132 + + P A P PP PG PP P P P PPPP L GM Sbjct: 466 LGAMAPPAPP------LPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLPGM 510 Score = 38.5 bits (88), Expect = 0.003 Identities = 29/78 (37%), Positives = 30/78 (38%), Gaps = 21/78 (26%) Query: 58 QPGALAYGAFGPPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAP 117 QP AL A PP P PPP PG +A PP P PP P Sbjct: 410 QPRALEQQASTPP------PPPPPPLL------------PGSSAEPPPPPPPPPLPSVGA 451 Query: 118 SA---AAPPPPAHALGGM 132 A A PPPP LG M Sbjct: 452 KALPTAPPPPPLPGLGAM 469 >gi|149999380 inverted formin 2 isoform 1 [Homo sapiens] Length = 1249 Score = 54.7 bits (130), Expect = 4e-08 Identities = 40/113 (35%), Positives = 47/113 (41%), Gaps = 20/113 (17%) Query: 33 PPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPAVPPPAAGIAH-LQP 91 PP P L S + + P PPPP PG GA PP+ P +PPP G L P Sbjct: 439 PPPPPPPLPS-VGAKALPTAPPPPPLPG---LGAMAPPA-----PPLPPPLPGSCEFLPP 489 Query: 92 VATPYPGRAAAPPNAP-------GGPPGPQPAPSAAAPPPPAHALGGMDAELI 137 P PG PP P G PP P P PP A GGM+ ++ Sbjct: 490 PPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLLPCTCSPPVA---GGMEEVIV 539 Score = 52.4 bits (124), Expect = 2e-07 Identities = 37/111 (33%), Positives = 43/111 (38%), Gaps = 15/111 (13%) Query: 26 PHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPAVPPPAAG 85 P AL P L P + PPPP P + GA P++ PPP G Sbjct: 411 PRALEQQASTPPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTA-----PPPPPLPG 465 Query: 86 IAHLQPVATPYPGRAAAPPNAPGG----PPGPQPAPSAAAPPPPAHALGGM 132 + + P A P PP PG PP P P P PPPP L GM Sbjct: 466 LGAMAPPAPP------LPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLPGM 510 Score = 38.5 bits (88), Expect = 0.003 Identities = 29/78 (37%), Positives = 30/78 (38%), Gaps = 21/78 (26%) Query: 58 QPGALAYGAFGPPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAP 117 QP AL A PP P PPP PG +A PP P PP P Sbjct: 410 QPRALEQQASTPP------PPPPPPLL------------PGSSAEPPPPPPPPPLPSVGA 451 Query: 118 SA---AAPPPPAHALGGM 132 A A PPPP LG M Sbjct: 452 KALPTAPPPPPLPGLGAM 469 >gi|146134388 YLP motif containing 1 [Homo sapiens] Length = 2146 Score = 54.7 bits (130), Expect = 4e-08 Identities = 44/121 (36%), Positives = 53/121 (43%), Gaps = 16/121 (13%) Query: 17 PPSAAAAHGPHAL-RTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPP----- 70 PPS P AL T+PP PG+ + P P PPP P +L+ + GPP Sbjct: 539 PPSLPPPVMPPALPATVPP---PGMPPPVMPPSLPTSVPPPGMPPSLS--SAGPPPVLPP 593 Query: 71 ---SSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNA--PGGPPGPQPAPSAAAPPPP 125 SS P P +PPP+ PV P +A PP P G P P AAP PP Sbjct: 594 PSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPP 653 Query: 126 A 126 A Sbjct: 654 A 654 Score = 48.1 bits (113), Expect = 4e-06 Identities = 38/112 (33%), Positives = 47/112 (41%), Gaps = 7/112 (6%) Query: 15 QRPPSAAAAHGPHALRTLPP-YAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPP-SS 72 Q PP P +LPP P L + + P G P PP P ++ P SS Sbjct: 525 QMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSS 584 Query: 73 FQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAAAPPP 124 P P +PPP+ A PV P + APP P P P S+A PPP Sbjct: 585 AGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPP-----PVMPLPPLSSATPPP 631 Score = 43.9 bits (102), Expect = 8e-05 Identities = 30/87 (34%), Positives = 36/87 (41%), Gaps = 19/87 (21%) Query: 53 PPPPRQPGALAYGAFGPPSSFQPFPAVPPPAAGIA------------HLQPVATP--YPG 98 PPPP PG YG + PP P P PPP ++ H Q P P Sbjct: 87 PPPPVMPGG-GYGDWQPP----PPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPM 141 Query: 99 RAAAPPNAPGGPPGPQPAPSAAAPPPP 125 +PP +P PPG PS + PPP Sbjct: 142 ELESPPESPPVPPGSYMPPSQSYMPPP 168 Score = 42.4 bits (98), Expect = 2e-04 Identities = 33/109 (30%), Positives = 47/109 (43%), Gaps = 8/109 (7%) Query: 41 DSGLRPRGAPLGPPPPR--QPGALAYGAFGPPSSFQPFPAVPPPAAGIAHLQPVATPYPG 98 D G P+ A PP Q + G + PP S++P P + P I ++P A P Sbjct: 1478 DFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSI--VRPSAPP--A 1533 Query: 99 RAAAPPNAPGGPPGPQPAPSAAAPPPPA--HALGGMDAELIDEEALTSL 145 R++ P P P P P P PPPP ++ E DE++ L Sbjct: 1534 RSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGL 1582 Score = 36.2 bits (82), Expect = 0.016 Identities = 30/101 (29%), Positives = 36/101 (35%), Gaps = 21/101 (20%) Query: 50 PLGPPPPRQPGALAYGAFGPPSSFQPFPAVPPPAAGIA------------------HLQP 91 P P PP P AL + GP S PA P + ++ +Q Sbjct: 15 PPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQC 74 Query: 92 VATPY---PGRAAAPPNAPGGPPGPQPAPSAAAPPPPAHAL 129 V P+ P PP PGG G P PPPP AL Sbjct: 75 VLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPAL 115 Score = 35.4 bits (80), Expect = 0.028 Identities = 26/82 (31%), Positives = 30/82 (36%), Gaps = 20/82 (24%) Query: 54 PPPRQPGALAYGAFGPPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPG----- 108 PPP P Y PP P +PPP + PV P PP P Sbjct: 517 PPPFVP----YSQMPPP-----LPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPP 567 Query: 109 ------GPPGPQPAPSAAAPPP 124 PPG P+ S+A PPP Sbjct: 568 SLPTSVPPPGMPPSLSSAGPPP 589 Score = 34.7 bits (78), Expect = 0.048 Identities = 27/107 (25%), Positives = 36/107 (33%), Gaps = 18/107 (16%) Query: 17 PPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPF 76 PP + ++ P + LPP + G+ P G P G PP Q Sbjct: 606 PPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPP------------------QLT 647 Query: 77 PAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAAAPP 123 A PPA+ Q P P P + PP P +A P Sbjct: 648 AAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGP 694 Score = 31.6 bits (70), Expect = 0.40 Identities = 36/127 (28%), Positives = 46/127 (36%), Gaps = 29/127 (22%) Query: 16 RPPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPP---RQPGALA--------- 63 +PP + R+ P P + P PL PPPP Q A+ Sbjct: 1520 KPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSF 1579 Query: 64 YGAF------GPPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAP 117 YG + G S F+ A P A PV P P ++ PP PG P P P Sbjct: 1580 YGLWDTNDEQGLNSEFKSETAAIPSA-------PVLPPPPVHSSIPP--PG--PVPMGMP 1628 Query: 118 SAAAPPP 124 + PPP Sbjct: 1629 PMSKPPP 1635 Score = 28.9 bits (63), Expect = 2.6 Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 3/69 (4%) Query: 55 PPRQPGALAYGAFGPPS-SFQPFPAVPPPAAGIAHLQPVATP-YPGRAAAPPNAPGGPPG 112 PP P + G++ PPS S+ P P PP QP P P + +PP+ P Sbjct: 146 PPESP-PVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPT 204 Query: 113 PQPAPSAAA 121 P + S+++ Sbjct: 205 PSYSSSSSS 213 >gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] Length = 538 Score = 54.7 bits (130), Expect = 4e-08 Identities = 41/106 (38%), Positives = 44/106 (41%), Gaps = 19/106 (17%) Query: 34 PYAGPGLDSGLRPRGAPLGPPPP---------RQPGALAYGAFGPPSSFQPFPAVPPPAA 84 P P + P P PPPP R P A A A PPS P PA P P A Sbjct: 115 PRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPS---PGPAQPGPRA 171 Query: 85 GIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAAA-----PPPP 125 A P+A P P AA P AP P P P+ AA PPPP Sbjct: 172 QRA--APLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPP 215 Score = 54.3 bits (129), Expect = 6e-08 Identities = 38/87 (43%), Positives = 41/87 (47%), Gaps = 9/87 (10%) Query: 46 PRGAPLGPPPPRQP-GALAYGAFGPPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAA-- 102 PR P PPR P GA A A P P PA PPP A +A P P AAA Sbjct: 102 PRRGATPPAPPRAPRGAPAAAAAAAPP---PTPAPPPPPAPVAAAAPARAPRAAAAAATA 158 Query: 103 PPNAPGGPPGPQP---APSAAAPPPPA 126 PP+ PGP+ AP AA PP PA Sbjct: 159 PPSPGPAQPGPRAQRAAPLAAPPPAPA 185 Score = 51.2 bits (121), Expect = 5e-07 Identities = 39/112 (34%), Positives = 44/112 (39%), Gaps = 15/112 (13%) Query: 17 PPSAAAAHGPH-------ALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGP 69 PP+ AA P A T PP GP R APL PPP A A P Sbjct: 136 PPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPP---APAAPPAVAP 192 Query: 70 PSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAAA 121 P+ + PPPA +A +P P P A P PP PQP P A Sbjct: 193 PAGPR---RAPPPA--VAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGA 239 Score = 48.1 bits (113), Expect = 4e-06 Identities = 42/115 (36%), Positives = 45/115 (39%), Gaps = 11/115 (9%) Query: 18 PSAAAAHGPHALRTLPPYAGP--GLDSGLRPRGAPLGP-----PPPRQPGALAYGAFGPP 70 P+AAAA P PP P PR A P P QPG A A P Sbjct: 119 PAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRA-APL 177 Query: 71 SSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAAAPPPP 125 ++ P PA PP A A P P P AA P P PP P P PPPP Sbjct: 178 AAPPPAPAAPPAVAPPA--GPRRAPPPAVAAREPPLP-PPPQPPAPPQQQQPPPP 229 Score = 35.4 bits (80), Expect = 0.028 Identities = 26/72 (36%), Positives = 27/72 (37%), Gaps = 5/72 (6%) Query: 69 PPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAA-----APP 123 PP PA P G A P P A PP AP P AP AA APP Sbjct: 101 PPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPP 160 Query: 124 PPAHALGGMDAE 135 P A G A+ Sbjct: 161 SPGPAQPGPRAQ 172 Score = 34.7 bits (78), Expect = 0.048 Identities = 26/86 (30%), Positives = 32/86 (37%), Gaps = 9/86 (10%) Query: 52 GPPPPR---------QPGALAYGAFGPPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAA 102 GP P R Q A+ ++ S++ V PP G P P AAA Sbjct: 63 GPEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGAPAAA 122 Query: 103 PPNAPGGPPGPQPAPSAAAPPPPAHA 128 AP P P P P+ A PA A Sbjct: 123 AAAAPPPTPAPPPPPAPVAAAAPARA 148 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 54.3 bits (129), Expect = 6e-08 Identities = 43/131 (32%), Positives = 53/131 (40%), Gaps = 22/131 (16%) Query: 14 VQRPPSAAAA---HGPHALRTLPPYAGPGLDS----GL-RPRGAPLGPPPPRQPGALAYG 65 +Q PPS P ++ T PP A P L S GL P +PL PPP+ P LA Sbjct: 569 LQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLAL- 627 Query: 66 AFGPPSSFQPFPAVPPPAAGIAHLQPVA----------TPYPGRAAAPPNAPGGPPGPQP 115 PP P P PP + +A P A P+ + P AP PP P Sbjct: 628 ---PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 684 Query: 116 APSAAAPPPPA 126 +A PP A Sbjct: 685 VSPSATPPSQA 695 Score = 51.2 bits (121), Expect = 5e-07 Identities = 42/118 (35%), Positives = 47/118 (39%), Gaps = 9/118 (7%) Query: 17 PPSAAAAHGPHA--LRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQ 74 P S A P A LPP P P +PL P P+ P ALA P S Sbjct: 610 PLSPLATPPPQAPPXLALPPLQAPPSPPASPPL-SPLATPSPQAPNALAVHLLQAPFSPP 668 Query: 75 PFPAVPPPAAGIAH--LQPVATP----YPGRAAAPPNAPGGPPGPQPAPSAAAPPPPA 126 P P V P + A + P ATP P AA P P PP P +A PPP A Sbjct: 669 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA 726 Score = 48.5 bits (114), Expect = 3e-06 Identities = 39/124 (31%), Positives = 49/124 (39%), Gaps = 20/124 (16%) Query: 18 PSAAAAH---GPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQ 74 P+A A H P + PP P P +P PP + P +LA PP Sbjct: 653 PNALAVHLLQAPFSPPPSPPVQAP-FSPPASPPVSPSATPPSQAPPSLA----APPLQVP 707 Query: 75 PFPAVPPPAAGIAHLQPVATPY---------PGRAAAPPNAPGGPPGPQPAPSAAAPP-- 123 P P PP + A P A P P A+PP +P P P+ P AAPP Sbjct: 708 PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQ 767 Query: 124 -PPA 126 PP+ Sbjct: 768 VPPS 771 Score = 47.8 bits (112), Expect = 5e-06 Identities = 44/128 (34%), Positives = 50/128 (39%), Gaps = 15/128 (11%) Query: 14 VQRPPSAAAAHGPHALRTLPPYAGPGLDSG------LRPRGAPLGP---PPPRQPGALAY 64 +Q PPS A+ T PP A P L + P P+ P PPPR P LA Sbjct: 704 LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAA 763 Query: 65 GAF----GPPSSFQPFP-AVPPPAAGIAHLQPVATPYPGRAAA-PPNAPGGPPGPQPAPS 118 PP+S P A PPP A A P P A+ P AP P P Sbjct: 764 PPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSP 823 Query: 119 AAAPPPPA 126 A PPP A Sbjct: 824 LATPPPQA 831 Score = 45.1 bits (105), Expect = 4e-05 Identities = 39/113 (34%), Positives = 43/113 (38%), Gaps = 5/113 (4%) Query: 15 QRPPSAAAAHGPHALRTLPPYAGP---GLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPS 71 +R PSA A R+L A P SG RG P P P QP A PP Sbjct: 225 RRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ 284 Query: 72 SFQPFPAVPPPAAGIAHLQPVATPYP-GRAAAPPNAPGGPPGPQPAPSAAAPP 123 P PA G P+ATP P G A P P P PA +PP Sbjct: 285 VTPPRKDA-APALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPP 336 Score = 44.7 bits (104), Expect = 5e-05 Identities = 40/127 (31%), Positives = 48/127 (37%), Gaps = 30/127 (23%) Query: 15 QRPPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQ 74 Q PPS AA P + PP + P +P PPP+ P LA PP Sbjct: 694 QAPPSLAAP--PLQVPPSPPASPPM---------SPSATPPPQAPPPLA----APPLQVP 738 Query: 75 PFPAVPPPAAGIAHLQPVATPY---------PGRAAAPPNAPGGPPGPQPAPSAAAPP-- 123 P P PP + A P P P A+ P +P P PQ P+ A PP Sbjct: 739 PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQ 798 Query: 124 ----PPA 126 PPA Sbjct: 799 ALPSPPA 805 Score = 43.9 bits (102), Expect = 8e-05 Identities = 45/131 (34%), Positives = 54/131 (41%), Gaps = 36/131 (27%) Query: 17 PPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAP-LGPP---PPRQPGALAYGAFG---- 68 P S+ A GP A T P A P S +P+G L PP PPR+ A A G Sbjct: 248 PLSSPARSGPSARGT--PRA-PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPL 304 Query: 69 ---------------PPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGP 113 P ++ P PA PP+ P+ATP P APP +P PP Sbjct: 305 ATPSPSGTKARPVPPPDNAATPLPATLPPS------PPLATPLP---LAPP-SPSAPPSL 354 Query: 114 QPAPSAAAPPP 124 Q PS A PP Sbjct: 355 QTLPSPPATPP 365 Score = 43.9 bits (102), Expect = 8e-05 Identities = 38/125 (30%), Positives = 47/125 (37%), Gaps = 27/125 (21%) Query: 18 PSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALA----YGAFGPPSSF 73 P+ P + T PP P + + PPP+ P ALA G PP S Sbjct: 564 PAPCPLQAPPSPLTTPPPETP----------SSIATPPPQAPPALASPPLQGLPSPPLS- 612 Query: 74 QPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQ----------PAPSAAAPP 123 P PP A L P+ P P A+PP +P P PQ AP + P Sbjct: 613 -PLATPPPQAPPXLALPPLQAP-PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS 670 Query: 124 PPAHA 128 PP A Sbjct: 671 PPVQA 675 Score = 43.9 bits (102), Expect = 8e-05 Identities = 42/124 (33%), Positives = 48/124 (38%), Gaps = 18/124 (14%) Query: 14 VQRPPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSF 73 +Q PPS A+ L PP A P L + P L PP PG F P +S Sbjct: 766 LQVPPSPPASLPMSPLAKPPPQAPPALAT---PPLQALPSPPASFPGQ---APFSPSASL 819 Query: 74 QPFP-AVPPPAAGIAHLQPVATPYPGRAAAPP-NAPGGPPGPQPAPS----------AAA 121 P A PPP A P+ P A+P AP PP P P S A Sbjct: 820 PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 879 Query: 122 PPPP 125 PPPP Sbjct: 880 PPPP 883 Score = 42.0 bits (97), Expect = 3e-04 Identities = 37/123 (30%), Positives = 48/123 (39%), Gaps = 19/123 (15%) Query: 13 LVQRPPSAAAAHGPHALRTLP------PYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGA 66 L + PP A A L+ LP P P S P +PL PPP+ P LA Sbjct: 781 LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM-SPLATPPPQAPPVLAAPL 839 Query: 67 FGPPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPN-----APGGPPGPQPAPSAAA 121 P S PP + + + TP P + + P APG PP P +PS+ Sbjct: 840 LQVPPS-------PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL 892 Query: 122 PPP 124 P Sbjct: 893 SGP 895 Score = 40.8 bits (94), Expect = 7e-04 Identities = 49/144 (34%), Positives = 54/144 (37%), Gaps = 35/144 (24%) Query: 13 LVQRPPSAAAAHGPHALRTLPP------YAGPGLDSGLRPRGAPLGPPPPRQPGALAYGA 66 L+Q PPS A+ A R P +GP L L P G P PPP R P + G Sbjct: 839 LLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP-GPP--PPPSRSPSSTLSGP 895 Query: 67 --FGPPSSFQPFP---------------AVPPPAAGIAHLQPVATPYPGRAAAPPNAPGG 109 G SS P A PPP A +A P A R APP A G Sbjct: 896 DLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW---SRGPAPPLAFRG 952 Query: 110 PPGPQPAPSAAAPPPPAHALGGMD 133 PG A P PPA G D Sbjct: 953 APG------APLPWPPATGPGSAD 970 Score = 40.0 bits (92), Expect = 0.001 Identities = 39/125 (31%), Positives = 45/125 (36%), Gaps = 29/125 (23%) Query: 19 SAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPR------QPGALAYGAFGPPSS 72 S++A P LR G DSG P G PPP P A + G PP + Sbjct: 901 SSSATSTPEELR--------GYDSG--PEGGAAASPPPDAELAACHPAAWSRGP-APPLA 949 Query: 73 FQPFPAVP---PPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAAAPPPPAHAL 129 F+ P P PPA G + T Y GP PAP A P P Sbjct: 950 FRGAPGAPLPWPPATGPGSADGLCTIYETE---------GPESATPAPGALDPGPSPGTS 1000 Query: 130 GGMDA 134 GG A Sbjct: 1001 GGKAA 1005 Score = 36.6 bits (83), Expect = 0.013 Identities = 42/123 (34%), Positives = 47/123 (38%), Gaps = 24/123 (19%) Query: 34 PYAGPGLDSGLR---PRGAPLGPPPPRQPGALAYGAFGPPSS--FQPFPAVPPPAAGIAH 88 P GP S L P G P PP A A PPS P P PP + Sbjct: 294 PALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPS 353 Query: 89 LQ----PVATPYPGRA---------AAPPNAPGGPPGPQP----APSAAAPPPPAHALGG 131 LQ P ATP P +A APP+ PP P +PS APP P AL Sbjct: 354 LQTLPSPPATP-PSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPL-ALSS 411 Query: 132 MDA 134 + A Sbjct: 412 LQA 414 Score = 35.4 bits (80), Expect = 0.028 Identities = 39/132 (29%), Positives = 51/132 (38%), Gaps = 19/132 (14%) Query: 28 ALRTLPPYAGPGLDSGLRPRGAPLGPPPP---------------RQPGALAYGAFGPPSS 72 A RT P PGL + RP G+P PPP R+P A G G + Sbjct: 13 AART-PAARAPGLLTP-RPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70 Query: 73 FQPFP-AVPPPAAGIAHLQPVATP-YPGRAAAPPNAPGGPPGPQPAPSAAAPPPPAHALG 130 + P A P +AG + P + P GR P A PGP +P A+ LG Sbjct: 71 PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG 130 Query: 131 GMDAELIDEEAL 142 + EE + Sbjct: 131 QKGLRISAEETV 142 Score = 35.4 bits (80), Expect = 0.028 Identities = 36/113 (31%), Positives = 45/113 (39%), Gaps = 16/113 (14%) Query: 19 SAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPA 78 S+ A+H P A L P L++ + L PP + P A PP P A Sbjct: 493 SSLASHSPQA--PLSSLIMPPLETQ-----SSLAPPSLQTPPA---SLTTPPLENLPSLA 542 Query: 79 VPPPAAGIA-----HLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAAAPPPPA 126 PP A HL+ P P APP+ PP P+ S A PPP A Sbjct: 543 PPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPP-PETPSSIATPPPQA 594 Score = 33.9 bits (76), Expect = 0.081 Identities = 43/151 (28%), Positives = 56/151 (37%), Gaps = 30/151 (19%) Query: 1 MADHLMLAEGYRLVQRPPSAAAAHGPHALRTLPP-YAGPGLDSGLRPRGAPLGPPPPRQP 59 +A H A L+ P ++ P +L+T P P L++ P PPP Q Sbjct: 495 LASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLEN------LPSLAPPPLQT 548 Query: 60 GA--LAYGAFGPPSSFQPFPAVPPPAAGIAHLQPVATPYP----GRAAAPPNAP------ 107 + L P P P PP+ P+ TP P A PP AP Sbjct: 549 ASAPLTTPHLETPPCPAPCPLQAPPS-------PLTTPPPETPSSIATPPPQAPPALASP 601 Query: 108 --GGPPGPQPAPSAAAPP--PPAHALGGMDA 134 G P P +P A PP PP AL + A Sbjct: 602 PLQGLPSPPLSPLATPPPQAPPXLALPPLQA 632 Score = 31.6 bits (70), Expect = 0.40 Identities = 38/119 (31%), Positives = 49/119 (41%), Gaps = 24/119 (20%) Query: 39 GLDSGLRPRGAPLGPP-PPRQPGALAYGAFGPPSSFQPFPAV---PPPAAGIAH-----L 89 G + GL PR AP P PP + + + S+ +P PA P G+ L Sbjct: 184 GTEVGL-PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242 Query: 90 QPVATPYPGRAAAPPNAPGGPPGP----QPAP---SAAAPP---PP----AHALGGMDA 134 ATP A + P+A G P P QP P A PP PP A ALG + + Sbjct: 243 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 301 Score = 30.4 bits (67), Expect = 0.90 Identities = 38/141 (26%), Positives = 47/141 (33%), Gaps = 33/141 (23%) Query: 12 RLVQRPPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPP------------PPRQP 59 R PP + P +L PP L + L P +PL P P Sbjct: 446 RPASTPPDSPPLQAPLSLPASPP-----LQTSLSPAVSPLSSPLTIHPLQALSSLASHSP 500 Query: 60 GALAYGAFGPP----SSFQPFPAVPPPAA----GIAHLQPVATPYPGRAAAPPNAPG--G 109 A PP SS P PPA+ + +L +A P A+AP P Sbjct: 501 QAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLET 560 Query: 110 PPGPQPAP------SAAAPPP 124 PP P P P PPP Sbjct: 561 PPCPAPCPLQAPPSPLTTPPP 581 Score = 27.7 bits (60), Expect = 5.8 Identities = 40/128 (31%), Positives = 44/128 (34%), Gaps = 38/128 (29%) Query: 16 RPP-SAAAAHGPHALRTLP-PYAGPGLDSGLRPRGAPLGPPPPR---------------- 57 RPP S P A T P P + PG SG R PLG R Sbjct: 93 RPPASGRGERAPPAKNTSPGPVSSPGRASGTT-RPGPLGQKGLRISAEETVARGKATEAP 151 Query: 58 QPGALAYGAFGPPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPG-PQPA 116 + AL+ GA S P P P PA A A G G P+PA Sbjct: 152 KRSALSAGARRDTSG--PTPGTPSPAM----------------ARRSRAAGTEVGLPRPA 193 Query: 117 PSAAAPPP 124 PSA PP Sbjct: 194 PSARPRPP 201 Score = 26.9 bits (58), Expect = 9.9 Identities = 31/118 (26%), Positives = 35/118 (29%), Gaps = 21/118 (17%) Query: 18 PSAAAAHGPHALRTLPPYAGPGLDSGL--------------RPRGAPLGPPPPRQPGALA 63 P A P A PP GPG GL P GP P G A Sbjct: 946 PPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAA 1005 Query: 64 YGAFGPPSSFQP-------FPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQ 114 GA SS P P A+ + HL A + GGP G + Sbjct: 1006 AGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAE 1063 >gi|160707881 formin 2 [Homo sapiens] Length = 1722 Score = 53.9 bits (128), Expect = 8e-08 Identities = 41/97 (42%), Positives = 43/97 (44%), Gaps = 10/97 (10%) Query: 32 LPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPAVPP-PAAGIAHLQ 90 LPP G G+ GA + PPPP PGA PP P PP P AGI Sbjct: 934 LPPLPGAGIPPPPPLPGAAIPPPPPL-PGAGI--PLPPPLPGAGIPPPPPLPGAGI---- 986 Query: 91 PVATPYPGRA-AAPPNAPG-GPPGPQPAPSAAAPPPP 125 P P PG PP PG G P P P P A PPPP Sbjct: 987 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1023 Score = 53.1 bits (126), Expect = 1e-07 Identities = 47/122 (38%), Positives = 51/122 (41%), Gaps = 26/122 (21%) Query: 18 PSAAAAHGPHALRT--LPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAY------GAFGP 69 PS A P T LPP P +G+ PPPP PGA GA P Sbjct: 892 PSTAIPQPPPLQGTEMLPPPPPPLPGAGI--------PPPPPLPGAGILPLPPLPGAGIP 943 Query: 70 PSSFQPFPAVPPP----AAGIAHLQPVATPYPGRA-AAPPNAPG-GPPGPQPAPSAAAPP 123 P P A+PPP AGI P+ P PG PP PG G P P P P A PP Sbjct: 944 PPPPLPGAAIPPPPPLPGAGI----PLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 999 Query: 124 PP 125 PP Sbjct: 1000 PP 1001 Score = 53.1 bits (126), Expect = 1e-07 Identities = 44/115 (38%), Positives = 47/115 (40%), Gaps = 21/115 (18%) Query: 17 PPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPF 76 PP AA P PP G G+ GA + PPPP GA PP P Sbjct: 946 PPLPGAAIPPP-----PPLPGAGIPLPPPLPGAGIPPPPPLP------GAGIPPPPPLPG 994 Query: 77 PAVPPP----AAGIAHLQPVATPYPGRA-AAPPNAPG-GPPGPQPAPSAAAPPPP 125 +PPP AGI P P PG PP PG G P P P P A PPPP Sbjct: 995 AGIPPPPPLPGAGI----PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1045 Score = 53.1 bits (126), Expect = 1e-07 Identities = 37/97 (38%), Positives = 40/97 (41%), Gaps = 12/97 (12%) Query: 33 PPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPAV----PPPAAGIAH 88 PP G G+ GA + PPPP PGA G PP P P PPP G+ Sbjct: 1056 PPLPGAGIPPPPPLPGAGIPPPPPL-PGA---GIPPPP----PLPGAGIPPPPPLPGVGI 1107 Query: 89 LQPVATPYPGRAAAPPNAPGGPPGPQPAPSAAAPPPP 125 P P G PP G P P P P A PPPP Sbjct: 1108 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1144 Score = 52.4 bits (124), Expect = 2e-07 Identities = 39/99 (39%), Positives = 42/99 (42%), Gaps = 16/99 (16%) Query: 33 PPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPAVPPP----AAGIAH 88 PP G G+ GA + PPPP GA PP P +PPP AGI Sbjct: 979 PPLPGAGIPPPPPLPGAGIPPPPPLP------GAGIPPPPPLPGAGIPPPPPLPGAGI-- 1030 Query: 89 LQPVATPYPGRA-AAPPNAPG-GPPGPQPAPSAAAPPPP 125 P P PG PP PG G P P P P A PPPP Sbjct: 1031 --PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1067 Score = 52.4 bits (124), Expect = 2e-07 Identities = 39/99 (39%), Positives = 42/99 (42%), Gaps = 16/99 (16%) Query: 33 PPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPAVPPP----AAGIAH 88 PP G G+ GA + PPPP GA PP P +PPP AGI Sbjct: 990 PPLPGAGIPPPPPLPGAGIPPPPPLP------GAGIPPPPPLPGAGIPPPPPLPGAGI-- 1041 Query: 89 LQPVATPYPGRA-AAPPNAPG-GPPGPQPAPSAAAPPPP 125 P P PG PP PG G P P P P A PPPP Sbjct: 1042 --PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1078 Score = 52.4 bits (124), Expect = 2e-07 Identities = 39/99 (39%), Positives = 42/99 (42%), Gaps = 16/99 (16%) Query: 33 PPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPAVPPP----AAGIAH 88 PP G G+ GA + PPPP GA PP P +PPP AGI Sbjct: 1001 PPLPGAGIPPPPPLPGAGIPPPPPLP------GAGIPPPPPLPGAGIPPPPPLPGAGI-- 1052 Query: 89 LQPVATPYPGRA-AAPPNAPG-GPPGPQPAPSAAAPPPP 125 P P PG PP PG G P P P P A PPPP Sbjct: 1053 --PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1089 Score = 52.4 bits (124), Expect = 2e-07 Identities = 39/99 (39%), Positives = 42/99 (42%), Gaps = 16/99 (16%) Query: 33 PPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPAVPPP----AAGIAH 88 PP G G+ GA + PPPP GA PP P +PPP AGI Sbjct: 1012 PPLPGAGIPPPPPLPGAGIPPPPPLP------GAGIPPPPPLPGAGIPPPPPLPGAGI-- 1063 Query: 89 LQPVATPYPGRA-AAPPNAPG-GPPGPQPAPSAAAPPPP 125 P P PG PP PG G P P P P A PPPP Sbjct: 1064 --PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1100 Score = 52.4 bits (124), Expect = 2e-07 Identities = 39/99 (39%), Positives = 42/99 (42%), Gaps = 16/99 (16%) Query: 33 PPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPAVPPP----AAGIAH 88 PP G G+ GA + PPPP GA PP P +PPP AGI Sbjct: 1034 PPLPGAGIPPPPPLPGAGIPPPPPLP------GAGIPPPPPLPGAGIPPPPPLPGAGI-- 1085 Query: 89 LQPVATPYPGRA-AAPPNAPG-GPPGPQPAPSAAAPPPP 125 P P PG PP PG G P P P P A PPPP Sbjct: 1086 --PPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPP 1122 Score = 52.0 bits (123), Expect = 3e-07 Identities = 41/121 (33%), Positives = 47/121 (38%), Gaps = 15/121 (12%) Query: 9 EGYRLVQRPPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFG 68 +G ++ PP G + PP G G+ L P PPPP PGA A Sbjct: 903 QGTEMLPPPPPPLPGAG---IPPPPPLPGAGI-LPLPPLPGAGIPPPPPLPGA----AIP 954 Query: 69 PPSSFQPFPA----VPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAAAPPP 124 PP P P +PPP G P P G PP G P P P P A PPP Sbjct: 955 PPP---PLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1011 Query: 125 P 125 P Sbjct: 1012 P 1012 Score = 51.6 bits (122), Expect = 4e-07 Identities = 44/106 (41%), Positives = 46/106 (43%), Gaps = 21/106 (19%) Query: 32 LPPYAGPGLDSGLRPRGAPLG------PPPPRQPGALAYGAFGPP----SSFQPFPAVPP 81 LP P L S P+ PL PPPP PGA G PP + P P P Sbjct: 883 LPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGA---GIPPPPPLPGAGILPLP--PL 937 Query: 82 PAAGIAHLQPVATPYPGRA-AAPPNAPG-GPPGPQPAPSAAAPPPP 125 P AGI P P PG A PP PG G P P P P A PPPP Sbjct: 938 PGAGI----PPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPP 979 Score = 51.6 bits (122), Expect = 4e-07 Identities = 39/99 (39%), Positives = 42/99 (42%), Gaps = 16/99 (16%) Query: 33 PPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPAVPPP----AAGIAH 88 PP G G+ GA + PPPP GA PP P +PPP AGI Sbjct: 1045 PPLPGAGIPPPPPLPGAGIPPPPPLP------GAGIPPPPPLPGAGIPPPPPLPGAGI-- 1096 Query: 89 LQPVATPYPGRA-AAPPNAPG-GPPGPQPAPSAAAPPPP 125 P P PG PP PG G P P P P A PPPP Sbjct: 1097 --PPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1133 Score = 50.8 bits (120), Expect = 6e-07 Identities = 38/99 (38%), Positives = 41/99 (41%), Gaps = 16/99 (16%) Query: 33 PPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPAVPPP----AAGIAH 88 PP G G+ GA + PPPP GA PP P +PPP AGI Sbjct: 1023 PPLPGAGIPPPPPLPGAGIPPPPPLP------GAGIPPPPPLPGAGIPPPPPLPGAGI-- 1074 Query: 89 LQPVATPYPGRA-AAPPNAPG-GPPGPQPAPSAAAPPPP 125 P P PG PP PG G P P P P PPPP Sbjct: 1075 --PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPP 1111 Score = 50.1 bits (118), Expect = 1e-06 Identities = 38/99 (38%), Positives = 41/99 (41%), Gaps = 16/99 (16%) Query: 33 PPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPAVPPP----AAGIAH 88 PP G G+ GA + PPPP GA PP P +PPP AGI Sbjct: 1067 PPLPGAGIPPPPPLPGAGIPPPPPLP------GAGIPPPPPLPGVGIPPPPPLPGAGI-- 1118 Query: 89 LQPVATPYPGRA-AAPPNAPG-GPPGPQPAPSAAAPPPP 125 P P PG PP PG G P P P P PPPP Sbjct: 1119 --PPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPP 1155 Score = 50.1 bits (118), Expect = 1e-06 Identities = 36/97 (37%), Positives = 38/97 (39%), Gaps = 12/97 (12%) Query: 33 PPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPAV----PPPAAGIAH 88 PP G G+ G + PPPP PGA G PP P P PPP G Sbjct: 1089 PPLPGAGIPPPPPLPGVGIPPPPPL-PGA---GIPPPP----PLPGAGIPPPPPLPGAGI 1140 Query: 89 LQPVATPYPGRAAAPPNAPGGPPGPQPAPSAAAPPPP 125 P P G PP G P P P P A PPPP Sbjct: 1141 PPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1177 Score = 49.3 bits (116), Expect = 2e-06 Identities = 37/99 (37%), Positives = 41/99 (41%), Gaps = 16/99 (16%) Query: 33 PPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPAVPPP----AAGIAH 88 PP G G+ GA + PPPP + PP P +PPP AGI Sbjct: 1122 PPLPGAGIPPPPPLPGAGIPPPPPLPRVGI------PPPPPLPGAGIPPPPPLPGAGI-- 1173 Query: 89 LQPVATPYPGRAAAPPNA-PG-GPPGPQPAPSAAAPPPP 125 P P PG PP PG G P P P P A PPPP Sbjct: 1174 --PPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPP 1210 Score = 48.9 bits (115), Expect = 2e-06 Identities = 35/95 (36%), Positives = 38/95 (40%), Gaps = 8/95 (8%) Query: 33 PPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPAVPPPAAGIAHLQPV 92 PP G G+ GA + PPPP GA PP P +PPP P Sbjct: 1100 PPLPGVGIPPPPPLPGAGIPPPPPLP------GAGIPPPPPLPGAGIPPPPPLPRVGIPP 1153 Query: 93 ATPYPGRA-AAPPNAPG-GPPGPQPAPSAAAPPPP 125 P PG PP PG G P P P P PPPP Sbjct: 1154 PPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPP 1188 Score = 48.5 bits (114), Expect = 3e-06 Identities = 36/84 (42%), Positives = 36/84 (42%), Gaps = 15/84 (17%) Query: 53 PPPPRQPG----ALAYGAFGPPSSFQ-----PFPAVPPPAAGIAHLQPVATPYPGRAAAP 103 PPPP PG L A P Q P P P P AGI P P PG P Sbjct: 878 PPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGI----PPPPPLPGAGILP 933 Query: 104 -PNAPG-GPPGPQPAPSAAAPPPP 125 P PG G P P P P AA PPPP Sbjct: 934 LPPLPGAGIPPPPPLPGAAIPPPP 957 Score = 48.1 bits (113), Expect = 4e-06 Identities = 38/105 (36%), Positives = 40/105 (38%), Gaps = 20/105 (19%) Query: 33 PPYAGPGLDSGLRPRGAPLG----PPPPRQPGALAYGAFGPPSSFQPFPAV----PPPAA 84 PP G G+ P PL PPPP PGA G PP P P PPP Sbjct: 1133 PPLPGAGI-----PPPPPLPRVGIPPPPPLPGA---GIPPPP----PLPGAGIPPPPPLP 1180 Query: 85 GIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAAAPPPPAHAL 129 G+ P P G PP G P P P P PP PA L Sbjct: 1181 GVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPL 1225 Score = 48.1 bits (113), Expect = 4e-06 Identities = 37/109 (33%), Positives = 40/109 (36%), Gaps = 31/109 (28%) Query: 33 PPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPAV----PPPAAGIAH 88 PP G G+ PPPP PGA G PP P P V PPP G+ Sbjct: 1155 PPLPGAGI------------PPPPPLPGA---GIPPPP----PLPGVGIPPPPPLPGVGI 1195 Query: 89 LQPVATPYPGRAAAPP------NAPGGPPGPQPAPSAAAPPPPAHALGG 131 P P PG PP P P P P P PPPP + G Sbjct: 1196 --PPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSG 1242 Score = 42.0 bits (97), Expect = 3e-04 Identities = 37/110 (33%), Positives = 41/110 (37%), Gaps = 16/110 (14%) Query: 33 PPYAGPGLDSGLRPRGAPLGPPPPRQ-----PGALAYGAFGPPSSFQPFPAVPPP----A 83 PP G G+ GA + PPPP P GA PP P +PPP Sbjct: 1078 PPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1137 Query: 84 AGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAAA---PPPPAHALG 130 AGI P P P PP G P P P A PPPP +G Sbjct: 1138 AGI----PPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVG 1183 Score = 36.2 bits (82), Expect = 0.016 Identities = 30/102 (29%), Positives = 34/102 (33%), Gaps = 6/102 (5%) Query: 33 PPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPAVPPPAAGIAHLQPV 92 PP G G+ G + PPPP + P P PA P P G P Sbjct: 1177 PPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPP 1236 Query: 93 ATPYPGRAAAPPNAP--GGPPGPQPAPSAAAPPPPAHALGGM 132 P G PP P G P P PPP L G+ Sbjct: 1237 LLPVSG----PPLLPQVGSSTLPTPQVCGFLPPPLPSGLFGL 1274 Score = 30.8 bits (68), Expect = 0.69 Identities = 26/81 (32%), Positives = 30/81 (37%), Gaps = 3/81 (3%) Query: 46 PRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPAVPP--PAAGIAHLQPVATPYPGRAAAP 103 P G P+ P P A P S+ PFP P AAG T G A Sbjct: 296 PGGLPVSEAPSL-PAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAF 354 Query: 104 PNAPGGPPGPQPAPSAAAPPP 124 +AP G PG + AP P Sbjct: 355 EDAPRGSPGEEWAPEVGEDAP 375 Score = 28.5 bits (62), Expect = 3.4 Identities = 21/71 (29%), Positives = 23/71 (32%), Gaps = 22/71 (30%) Query: 80 PPPAAGIAHLQPVATPYPGRAAAPPNAPGGP---------------------PGPQPAPS 118 P G+ L PV PGR PP A GP QP S Sbjct: 748 PTEEGGVLTLPPV-DGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQS 806 Query: 119 AAAPPPPAHAL 129 + PPPP L Sbjct: 807 ISQPPPPPSLL 817 >gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD subunit [Homo sapiens] Length = 551 Score = 53.5 bits (127), Expect = 1e-07 Identities = 42/103 (40%), Positives = 46/103 (44%), Gaps = 10/103 (9%) Query: 30 RTLPPYAGPGLDSGLRPRGA-PLGPPPPRQPGALAYGAFGPPSSFQPFPAVPPPAAGIAH 88 R PP PG G P G P GPPPP PG YG PP P PPP Sbjct: 272 RPPPPVLFPGQPFGQPPLGPLPPGPPPP-VPG---YGP--PPGPPPPQQGPPPPPGPFPP 325 Query: 89 LQPVATPYPGRAAAPPNAPGGPPG-PQPAP--SAAAPPPPAHA 128 P P A PP+ PG PPG P PAP + A PPP ++ Sbjct: 326 RPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNS 368 Score = 47.8 bits (112), Expect = 5e-06 Identities = 43/121 (35%), Positives = 44/121 (36%), Gaps = 29/121 (23%) Query: 33 PPYAGPG-----LDSGLRPRGAPLGPP-PPRQPGALAYGAFGPPSSFQPFPAVPPPAAGI 86 P AGPG +G P PLGPP PP PG PP P P PP G Sbjct: 218 PGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGP------PPPGQVLPPPLAGPPNRGD 271 Query: 87 AHLQPVATPY---------PGRAAAPPNAPG-----GPPGPQ---PAPSAAAPPPPAHAL 129 PV P P PP PG GPP PQ P P PP P L Sbjct: 272 RPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPL 331 Query: 130 G 130 G Sbjct: 332 G 332 Score = 42.7 bits (99), Expect = 2e-04 Identities = 47/169 (27%), Positives = 61/169 (36%), Gaps = 29/169 (17%) Query: 17 PPSAAAAHGPHA-----LRTLPPYAGPGLDSGLRPRGAPLG-PPPPRQPGALAYGAFGPP 70 PP +GP + PP GP P G PL PPP PG Sbjct: 296 PPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPG---------- 345 Query: 71 SSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAAAPPPPAHALG 130 P P PPPA H+ P P P + P + GPP P PPP Sbjct: 346 ----PPPGAPPPA---PHVNPAFFPPPTNSGMPTSDSRGPP---PTDPYGRPPPYDRGDY 395 Query: 131 GMDAELID--EEALTSLELELGLHRVRELPELFLGQSEFDCFS-DLGSA 176 G +D L+ E E ++R R + + ++ D + D GSA Sbjct: 396 GPPGREMDTARTPLSEAEFEEIMNRNRAISSSAISRAVSDASAGDYGSA 444 Score = 40.4 bits (93), Expect = 9e-04 Identities = 37/118 (31%), Positives = 41/118 (34%), Gaps = 30/118 (25%) Query: 37 GPGLDSGLRPRG----APLGPP-----------PPRQPGALAYGAFGPPSSFQPFPAVPP 81 G G G P G P GP PPR P G GPP P +PP Sbjct: 203 GRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLG-PPGPPGPPGPPPPGQVLPP 261 Query: 82 PAAGIAH---LQPVATPYPGR-----------AAAPPNAPGGPPGPQPAPSAAAPPPP 125 P AG + P +PG+ PP PG P P P P PPPP Sbjct: 262 PLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPP 319 Score = 36.6 bits (83), Expect = 0.013 Identities = 34/97 (35%), Positives = 38/97 (39%), Gaps = 26/97 (26%) Query: 36 AGP--GLDSGLRPRGAPLGPPPPRQPGALAYG-AFGPPSSFQPFPAVPPPAAGIAHLQPV 92 AGP G P+G G R PGA+ G F P+ P PPP Sbjct: 186 AGPPGGSSRAAFPQG---GRGRGRFPGAVPGGDRFPGPAG----PGGPPP---------- 228 Query: 93 ATPYPGRAAAPPNAPGGPPGPQPAPSAAAPPPPAHAL 129 P+P PP P GPPGP P PPPP L Sbjct: 229 --PFPA-GQTPPRPPLGPPGP---PGPPGPPPPGQVL 259 >gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] Length = 502 Score = 53.1 bits (126), Expect = 1e-07 Identities = 42/111 (37%), Positives = 45/111 (40%), Gaps = 13/111 (11%) Query: 17 PPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLG--PPPPRQPGALAYGAFGPPSSFQ 74 PP + G + L P G SG P PLG PPPP G G GPP Sbjct: 314 PPPPPPSRGGNQLPRPPIVGGNKGRSGPLPP-VPLGIAPPPPTPRGPPPPGRGGPPPP-- 370 Query: 75 PFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAAAPPPP 125 PPPA G P+ P PG A PP P PP P P S P PP Sbjct: 371 -----PPPATG--RSGPLPPPPPG-AGGPPMPPPPPPPPPPPSSGNGPAPP 413 >gi|22027541 programmed cell death 7 [Homo sapiens] Length = 485 Score = 52.8 bits (125), Expect = 2e-07 Identities = 42/115 (36%), Positives = 47/115 (40%), Gaps = 26/115 (22%) Query: 32 LPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPAVPPP--------- 82 LPP+ G G RP GPPPP+ P +G PP P PA PPP Sbjct: 3 LPPFFGQG-----RP-----GPPPPQPPPPAPFGCPPPPL---PSPAFPPPLPQRPGPFP 49 Query: 83 AAGIAHLQPVATPYPGRAAAPPNAPGGPPG---PQPAPSAAAPPPPAHALGGMDA 134 A LQP P RA+A + GG G P P P PPP G DA Sbjct: 50 GASAPFLQPPLALQP-RASAEASRGGGGAGAFYPVPPPPLPPPPPQCRPFPGTDA 103 Score = 47.4 bits (111), Expect = 7e-06 Identities = 43/127 (33%), Positives = 48/127 (37%), Gaps = 21/127 (16%) Query: 15 QRPPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAP--------LGPPPPRQPGALAYGA 66 Q PP A P PP P L R P L PP QP A A + Sbjct: 18 QPPPPAPFGCPP------PPLPSPAFPPPLPQRPGPFPGASAPFLQPPLALQPRASAEAS 71 Query: 67 FGPPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAA---APP 123 G + +P PPP + P P+PG A P PPGP P S APP Sbjct: 72 RGGGGAGAFYPVPPPP---LPPPPPQCRPFPGTDAGERPRPP-PPGPGPPWSPRWPEAPP 127 Query: 124 PPAHALG 130 PPA LG Sbjct: 128 PPADVLG 134 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 52.4 bits (124), Expect = 2e-07 Identities = 41/118 (34%), Positives = 45/118 (38%), Gaps = 11/118 (9%) Query: 17 PPSAAAAHGPHALRTLPPYAGPGLDSGLR---PRGAPLGPPPPRQPGALAYGAFGPPSSF 73 P A P T P P G P+GAP PP P +L G PP Sbjct: 1228 PKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPT--PPAATPPSLKGGLATPPHKG 1285 Query: 74 QPFPAV---PPPAAGIAHLQPVATPYPGRAA--APPNAPGGPPGP-QPAPSAAAPPPP 125 P PAV P P G A P P P A +P +PG PP P P A PP P Sbjct: 1286 APNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSP 1343 Score = 50.8 bits (120), Expect = 6e-07 Identities = 43/119 (36%), Positives = 49/119 (41%), Gaps = 13/119 (10%) Query: 18 PSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPP--PPRQPGALAYGAF-GPPSSFQ 74 PS A P A P GP S P+GAP+ P PP G LA G P++ Sbjct: 1074 PSLKGAPTPPAATPPSPKGGPATPS---PKGAPMPPAATPPSPKGGLATPPHKGAPTT-- 1128 Query: 75 PFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGG----PPGPQPAPSAAAPPPPAHAL 129 P P P G+A P P AA PP+ GG PP P AA PP P L Sbjct: 1129 PAATPPSPKGGLATPPPKGAP-TTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL 1186 Score = 49.7 bits (117), Expect = 1e-06 Identities = 41/116 (35%), Positives = 48/116 (41%), Gaps = 17/116 (14%) Query: 18 PSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGP---PPPRQPGALAYGAFGPPSSFQ 74 PS A P A P GP S P+GAP P PP + G G P+ Sbjct: 957 PSPKWAPTPPAATPPSPKGGPATPS---PKGAPTPPAATPPSPKGGPATPSPKGAPTP-- 1011 Query: 75 PFPAVPPPAAGIAHLQPVATPYPGRAAAPPNA----PGGPPGPQPAPSAAAPPPPA 126 PAV PP+ + P ATP+P A+ PP A P G P P P A P A Sbjct: 1012 --PAVTPPSPKGS---PAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAA 1062 Score = 49.7 bits (117), Expect = 1e-06 Identities = 41/118 (34%), Positives = 50/118 (42%), Gaps = 11/118 (9%) Query: 17 PPSAAAAHGPHALRTLPPYAGPGLDSGLR---PRGAPLGPP--PPRQPGALAYGA-FGPP 70 P A P T P P GL P+GAP P PP G LA + G P Sbjct: 1159 PKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP 1218 Query: 71 SSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGP--PGPQPAPSAAAPPPPA 126 ++ P P P G+A P P AA PP+ GGP P P+ AP+ A PP+ Sbjct: 1219 TT--PAATPPSPKGGLATPSPKGAPTTP-AATPPSPKGGPATPPPKGAPTPPAATPPS 1273 Score = 48.5 bits (114), Expect = 3e-06 Identities = 43/127 (33%), Positives = 51/127 (40%), Gaps = 22/127 (17%) Query: 18 PSAAAAHGPHALRTLPPYAG---------PGLDSGLR---PRGAPLGP--PPPRQPGALA 63 P AA P PP+ G P GL P+GAP P PP G L Sbjct: 1105 PPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL- 1163 Query: 64 YGAFGPPSSFQPFPAVPPPA--AGIAHLQPVATPYPGRAAAPPNAPGG--PPGPQPAPSA 119 A PP PA PP+ G+A P P AA PP+ GG P P+ AP+ Sbjct: 1164 --ATPPPKGAPTTPAATPPSPKGGLATPSPKGAP-TTPAATPPSPKGGLATPSPKGAPTT 1220 Query: 120 AAPPPPA 126 A PP+ Sbjct: 1221 PAATPPS 1227 Score = 47.0 bits (110), Expect = 9e-06 Identities = 40/122 (32%), Positives = 48/122 (39%), Gaps = 20/122 (16%) Query: 15 QRPPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQ 74 Q P + + P R P A G+ + P+GAP PP P + G P + Sbjct: 907 QAPALSMTSSSPKKARATP--APKGIPASPSPKGAPT--PPAATPPSPKGGPATPSPKWA 962 Query: 75 PFP--AVPPPAAGIAHLQPVATPYPGR-----AAAPPNAPGGPPGPQ----PAPSAAAPP 123 P P A PP G ATP P AA PP+ GGP P P P A PP Sbjct: 963 PTPPAATPPSPKG-----GPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPP 1017 Query: 124 PP 125 P Sbjct: 1018 SP 1019 Score = 47.0 bits (110), Expect = 9e-06 Identities = 41/125 (32%), Positives = 47/125 (37%), Gaps = 18/125 (14%) Query: 12 RLVQRPPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPP---PRQPGALAYGAFG 68 R P A+ P T PP A P P+G P P P P P A G Sbjct: 922 RATPAPKGIPASPSPKGAPT-PPAATPP-----SPKGGPATPSPKWAPTPPAATPPSPKG 975 Query: 69 PPSSFQPFPAVPPPAA-------GIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAAA 121 P++ P A PPAA G A P P P A P +P G P P P A+ Sbjct: 976 GPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTP--PAVTPPSPKGSPAATPFPKGAS 1033 Query: 122 PPPPA 126 PP A Sbjct: 1034 TPPAA 1038 Score = 46.6 bits (109), Expect = 1e-05 Identities = 42/119 (35%), Positives = 50/119 (42%), Gaps = 19/119 (15%) Query: 18 PSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAP----LGPPPPR-QPGALAY--GAFGPP 70 PS A P A P GP S P+GAP + PP P+ P A + GA PP Sbjct: 980 PSPKGAPTPPAATPPSPKGGPATPS---PKGAPTPPAVTPPSPKGSPAATPFPKGASTPP 1036 Query: 71 SSFQPFPAVPPPAAGI---AHLQPVAT-PYPGRAAAPPNAPGGPPGPQPAPSAAAPPPP 125 ++ P P P A + A P AT P P A P+ G P P AA PP P Sbjct: 1037 AATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGA-----PTPPAATPPSP 1090 Score = 45.8 bits (107), Expect = 2e-05 Identities = 40/119 (33%), Positives = 46/119 (38%), Gaps = 13/119 (10%) Query: 17 PPSAAAAHGPHALRTLPPYAGPGLDSGLR---PRGAPLGPP--PPRQPGALAYGA-FGPP 70 P A P T P P GL P+GAP P PP G LA + G P Sbjct: 1182 PKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP 1241 Query: 71 SSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGG----PPGPQPAPSAAAPPPP 125 ++ P P P G A P P P AA PP+ GG P P P+ PP P Sbjct: 1242 TT--PAATPPSPKGGPATPPPKGAPTP-PAATPPSLKGGLATPPHKGAPNPAVVTPPSP 1297 Score = 42.7 bits (99), Expect = 2e-04 Identities = 38/125 (30%), Positives = 47/125 (37%), Gaps = 17/125 (13%) Query: 17 PPSAAAAHGPHALRTLPPYAG---PGLDSGLRPRGAPLGPPP---PRQPGALAYGAFGPP 70 PP+A L T PP+ G P + + P+G P PP P P A G P Sbjct: 1266 PPAATPPSLKGGLAT-PPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSP 1324 Query: 71 SSFQPF-----PAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPS-----AA 120 + P PAV PP+ P TP P++ GP P PS A Sbjct: 1325 GTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAM 1384 Query: 121 APPPP 125 PP P Sbjct: 1385 TPPSP 1389 Score = 40.8 bits (94), Expect = 7e-04 Identities = 46/140 (32%), Positives = 56/140 (40%), Gaps = 32/140 (22%) Query: 17 PPSAAAAHGPHALR-------TLPPYAGP--GLDSGLRPRGAPLGPPPPRQPGALAYGAF 67 PPS A P A+ TLPP P + + P+ P P P + P AL+ + Sbjct: 858 PPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAP-ALSMTSS 916 Query: 68 GP------------PSSFQPFPAVPPPAAGIAHLQP-VATPYPGR-----AAAPPNAPGG 109 P P+S P A PPAA + ATP P AA PP+ GG Sbjct: 917 SPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGG 976 Query: 110 PPGPQ----PAPSAAAPPPP 125 P P P P AA PP P Sbjct: 977 PATPSPKGAPTPPAATPPSP 996 Score = 40.8 bits (94), Expect = 7e-04 Identities = 40/122 (32%), Positives = 43/122 (35%), Gaps = 14/122 (11%) Query: 19 SAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSS------ 72 S AA P T PP A P G P PL P P A G P++ Sbjct: 1022 SPAATPFPKGAST-PPAATPPSPKG-SPAATPLPKGAPTTPAATLPSPKGGPATPSLKGA 1079 Query: 73 -FQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGG----PPGPQPAPSAAAPPPPAH 127 P P P G A P P P AA PP+ GG P P AA PP P Sbjct: 1080 PTPPAATPPSPKGGPATPSPKGAPMP-PAATPPSPKGGLATPPHKGAPTTPAATPPSPKG 1138 Query: 128 AL 129 L Sbjct: 1139 GL 1140 Score = 38.9 bits (89), Expect = 0.003 Identities = 36/111 (32%), Positives = 45/111 (40%), Gaps = 15/111 (13%) Query: 18 PSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPS--SFQP 75 P A P PP A P P+G+P G PPP+ GA A PPS Sbjct: 1297 PKGGPATSPPKGAPTPPAATPP-----SPKGSP-GTPPPK--GAPTPPAVTPPSPKGTPT 1348 Query: 76 FPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGG----PPGPQPAPSAAAP 122 PA P + G P + P AA P+ GG PP P+ P+ +P Sbjct: 1349 LPATTPSSKG-GPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSP 1398 Score = 37.0 bits (84), Expect = 0.010 Identities = 34/116 (29%), Positives = 46/116 (39%), Gaps = 15/116 (12%) Query: 17 PPSAAAAH-GPHALRTLPPYAGPGLDSGLRPRGAPLGPP-----PPRQPGA--LAYGAFG 68 PP+A +H G A+ P GP + S P+G P P P + P GA Sbjct: 1371 PPAATPSHKGGPAMTPPSPKRGPAIPS---PKGDPTSPAVIPLSPKKAPATPVTREGAAT 1427 Query: 69 PPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAAAPPP 124 P PAV P ++ + AT P A P++ G P P P + PP Sbjct: 1428 PSKGDLTPPAVTP----VSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPP 1479 Score = 34.7 bits (78), Expect = 0.048 Identities = 34/112 (30%), Positives = 40/112 (35%), Gaps = 15/112 (13%) Query: 19 SAAAAHGPHALRTLPPYAG---PGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQP 75 S A H P T P G P + L P+G L PP P P Sbjct: 849 SPATTHSP----TPPSPKGAPTPSAVTPLSPKGVTL--PPKETPTPSVVNLPFPKEG--- 899 Query: 76 FPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPS--AAAPPPP 125 PA P P A ++P RA P P P+ AP+ AA PP P Sbjct: 900 -PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSP 950 Score = 33.9 bits (76), Expect = 0.081 Identities = 32/110 (29%), Positives = 41/110 (37%), Gaps = 11/110 (10%) Query: 26 PHALRTLPPYAGPGLDSGLRPRGAPLGPP------PPRQPGALAYGAFGPPSSFQPFPAV 79 P A+ P P + + P+ AP P PP + GA P P PAV Sbjct: 1550 PPAMTVPSPKKTPAIPT---PKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIP-PAV 1605 Query: 80 PPPAAGIAHLQPVATP-YPGRAAAPPNAPGGPPGPQPAPSAAAPPPPAHA 128 P+ A P TP P + A P G P P PS+ P + A Sbjct: 1606 TSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPA 1655 Score = 26.9 bits (58), Expect = 9.9 Identities = 29/110 (26%), Positives = 36/110 (32%), Gaps = 11/110 (10%) Query: 26 PHALRTLPPYAGPGLDSGLRPRGAPLGPPP----PRQPGALAYGAFGP-----PSSFQPF 76 P A LP GP + +P+ P P LA A P S+F P Sbjct: 97 PEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPN 156 Query: 77 PAVPPPAAGIAHLQPVATPYPGRAAAPP--NAPGGPPGPQPAPSAAAPPP 124 PP+ +A V T A + P N P P P PP Sbjct: 157 LLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPP 206 Score = 26.9 bits (58), Expect = 9.9 Identities = 35/138 (25%), Positives = 49/138 (35%), Gaps = 24/138 (17%) Query: 10 GYRLVQRPPSAAAAHGPHALRTL---------PPYAGPGLDSGLRPRGAPLGPPPPRQPG 60 G + Q A GP AL+ + P P + + PP P Sbjct: 1662 GATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPS 1721 Query: 61 ALAYGAFGPPSSFQPFPAVPPPA----------AGIAHLQPVATPYPGRAAAPPNAPGGP 110 A G+ GP S+ P P +P A + P+A P +A+ P A Sbjct: 1722 A-KNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPP-ESKASTPLTAAAFE 1779 Query: 111 ---PGPQPAPSAAAPPPP 125 P P+ A +AAP PP Sbjct: 1780 KVLPKPESASVSAAPSPP 1797 >gi|210032580 SET domain containing 1B [Homo sapiens] Length = 1923 Score = 52.0 bits (123), Expect = 3e-07 Identities = 42/115 (36%), Positives = 44/115 (38%), Gaps = 13/115 (11%) Query: 18 PSAAAAHGPHALR-TLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPF 76 P AAA P L TLP PG P P PPPP QPG F P P Sbjct: 664 PGAAAVAAPSVLAPTLPLPPPPGF-----PPLPPPPPPPPPQPG------FPMPPPLPPP 712 Query: 77 PAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAAAPPPPAHALGG 131 P PPPA + P P P PP P PP P P +H LGG Sbjct: 713 PPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFP-PGLFPVMQVDMSHVLGG 766 Score = 46.2 bits (108), Expect = 2e-05 Identities = 41/118 (34%), Positives = 48/118 (40%), Gaps = 15/118 (12%) Query: 15 QRPPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLG--PPPPRQPGALAYGAFGPPSS 72 Q SA AH P + P PG S P P+ PPPP +P A A AFG S Sbjct: 371 QPQDSATFAHTPPPAQATP---APGFKSAFSPYQTPVAHFPPPPEEPTATA--AFGARDS 425 Query: 73 --FQPFPAVP--PPAAGIAHLQPVATPYPGRAAAPPNAPGGPP----GPQPAPSAAAP 122 F+ PA P PPA +A +P P P GG P P+P S P Sbjct: 426 GEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTP 483 Score = 46.2 bits (108), Expect = 2e-05 Identities = 29/83 (34%), Positives = 31/83 (37%), Gaps = 19/83 (22%) Query: 59 PGALAYGA---------FGPPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGG 109 PGA A A PP F P P PPP P PG PP P Sbjct: 664 PGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPP----------PQPGFPMPPPLPPPP 713 Query: 110 PPGPQPAPSAAAPPPPAHALGGM 132 PP P P+ PPPP A G+ Sbjct: 714 PPPPPAHPAVTVPPPPLPAPPGV 736 Score = 35.0 bits (79), Expect = 0.036 Identities = 25/87 (28%), Positives = 32/87 (36%), Gaps = 16/87 (18%) Query: 55 PPRQPGALAYGAF-----GPPSSFQPFPAVPPPAAGIAHLQ-----PVATPYPGRAAAPP 104 PP +PG GA P + P + P A L+ P+ P P + PP Sbjct: 1225 PPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPP 1284 Query: 105 NAPGGPPGPQPAPSA------AAPPPP 125 P PP P P P + PP P Sbjct: 1285 PRPPRPPSPPPEPETTDASHPSVPPEP 1311 Score = 33.9 bits (76), Expect = 0.081 Identities = 27/68 (39%), Positives = 30/68 (44%), Gaps = 12/68 (17%) Query: 62 LAYGAFGPP--SSFQPFPAVPPPAAGIAHLQP--VATPYPGRAAAPPNAPGGPPGPQPAP 117 L +GA G SS PF A P +A AH P ATP PG +A P P Sbjct: 352 LPFGAVGGTGGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSA--------FSPYQTP 403 Query: 118 SAAAPPPP 125 A PPPP Sbjct: 404 VAHFPPPP 411 Score = 28.9 bits (63), Expect = 2.6 Identities = 17/51 (33%), Positives = 17/51 (33%) Query: 75 PFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAAAPPPP 125 P P V P A V P P P PP P P P P PP Sbjct: 657 PKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPP 707 Score = 28.1 bits (61), Expect = 4.5 Identities = 35/123 (28%), Positives = 41/123 (33%), Gaps = 19/123 (15%) Query: 5 LMLAEGYRLVQRPPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAP-----LGPPPPRQP 59 L L R R P+ P L + PP P RPR +P L P R P Sbjct: 1441 LALPAVLRAQARAPTPLPPLLPAPLASCPP---PMKRKPGRPRRSPPSMLSLDGPLVRPP 1497 Query: 60 GALAYGAF-----GPPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQ 114 A G G P + FP+ P + P P PP P PP P Sbjct: 1498 AGAALGRELLLLPGQPQT-PVFPSTHDPRTVTLDFRNAGIPAP-----PPPLPPQPPPPP 1551 Query: 115 PAP 117 P P Sbjct: 1552 PPP 1554 Score = 28.1 bits (61), Expect = 4.5 Identities = 31/102 (30%), Positives = 40/102 (39%), Gaps = 8/102 (7%) Query: 17 PPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGP--PPPRQPGA--LAYGAFGPPSS 72 PPS + GP L P A G + L P G P P P P L + G P+ Sbjct: 1483 PPSMLSLDGP--LVRPPAGAALGRELLLLP-GQPQTPVFPSTHDPRTVTLDFRNAGIPAP 1539 Query: 73 FQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQ 114 P P PPP ++P P+ P + PPGP+ Sbjct: 1540 PPPLPPQPPPPPPPPPVEPTKLPFKELDNQWP-SEAIPPGPR 1580 Score = 27.3 bits (59), Expect = 7.6 Identities = 29/100 (29%), Positives = 35/100 (35%), Gaps = 11/100 (11%) Query: 9 EGYRLVQRPPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFG 68 EG L+ P A A L P P D + P P+ P P QP Sbjct: 1234 EGAMLLSPEPPAKEVE---ARPPLSPERAPEHDLEVEPE-PPMMLPLPLQP------PLP 1283 Query: 69 PPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPG 108 PP +P P+ PP P P P PP+ PG Sbjct: 1284 PPRPPRP-PSPPPEPETTDASHPSVPPEPLAEDHPPHTPG 1322 Score = 26.9 bits (58), Expect = 9.9 Identities = 27/86 (31%), Positives = 31/86 (36%), Gaps = 1/86 (1%) Query: 36 AGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPAVPPPAAGIAHLQPVATP 95 +GP L G PL P P P LA A + P P P A +A P Sbjct: 1416 SGPLASPVLLETGLPLPLPLPL-PLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKR 1474 Query: 96 YPGRAAAPPNAPGGPPGPQPAPSAAA 121 PGR P + GP P A A Sbjct: 1475 KPGRPRRSPPSMLSLDGPLVRPPAGA 1500 Score = 26.9 bits (58), Expect = 9.9 Identities = 27/96 (28%), Positives = 32/96 (33%), Gaps = 22/96 (22%) Query: 49 APLG---PPPPRQPGALAYGAFGPPSSFQ-PFPAVPPPAAGIAHLQPVATPYPGRAAAPP 104 APL PP R+PG PPS P V PPA + + P + P Sbjct: 1463 APLASCPPPMKRKPGRPRRS---PPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFP 1519 Query: 105 NA---------------PGGPPGPQPAPSAAAPPPP 125 + P PP P P PPPP Sbjct: 1520 STHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPP 1555 >gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] Length = 416 Score = 51.6 bits (122), Expect = 4e-07 Identities = 37/111 (33%), Positives = 43/111 (38%), Gaps = 9/111 (8%) Query: 17 PPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGA--PLGPPPPRQPGALAYGAFGPPSSFQ 74 PP P ++ P + PG G P+G P GPPPP PG GPP Sbjct: 94 PPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPP--PGKPQ----GPPPQGG 147 Query: 75 PFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAAAPPPP 125 P PPP P + +PP P GPP PQ PPPP Sbjct: 148 NKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPP-PQGGNQPQGPPPP 197 Score = 47.8 bits (112), Expect = 5e-06 Identities = 44/139 (31%), Positives = 49/139 (35%), Gaps = 38/139 (27%) Query: 9 EGYRLVQRPPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFG 68 +G Q PP GP PP G S P G P GPPP Q G G Sbjct: 269 QGGNKPQGPPPPGKPQGP------PPQGGSKSRSSRSPPGKPQGPPP--QGGNQPQGPPP 320 Query: 69 PPSSFQPFPAVPPPAAGIAHLQPVATPYPGR--------------AAAPPNAPGGPP--- 111 PP P PPP G +P P PG+ A +PP P GPP Sbjct: 321 PPGK----PQGPPPQGGN---KPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQE 373 Query: 112 -----GPQPAPSAAAPPPP 125 GP P P+ P P Sbjct: 374 GNNPQGP-PPPAGGNPQQP 391 Score = 47.4 bits (111), Expect = 7e-06 Identities = 39/125 (31%), Positives = 47/125 (37%), Gaps = 9/125 (7%) Query: 9 EGYRLVQRPPSAAAAHGPHAL---RTLPPYAGPGLDSGLRPRGA--PLGPPPP--RQPGA 61 +G Q PP GP ++ + PG G P+G P GPPPP + G Sbjct: 145 QGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 204 Query: 62 LAYGAFGPPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPG-GPPGPQPAPSAA 120 G P P PP G Q +P PG+ PP G P GP P P Sbjct: 205 PPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSP-PGKPQGPPPQGGNQPQGPPPPPGKP 263 Query: 121 APPPP 125 PPP Sbjct: 264 QGPPP 268 Score = 47.0 bits (110), Expect = 9e-06 Identities = 46/140 (32%), Positives = 50/140 (35%), Gaps = 38/140 (27%) Query: 9 EGYRLVQRPPSAAAA-HGPHALRTLPPYAG---------PGLDSGLRPRGA--PLGPPPP 56 +G Q PPS GP PP G PG G P+G P GPPPP Sbjct: 42 QGGNKPQGPPSPPGKPQGP------PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP 95 Query: 57 RQP------GALAYGAFGPPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGP 110 +P G + PP P PPP G QP P PP P GP Sbjct: 96 GKPQGPPPQGDKSRSPRSPPGK----PQGPPPQGGN---QPQGPP------PPPGKPQGP 142 Query: 111 PGPQPAPSAAAPPPPAHALG 130 P PQ PPPP G Sbjct: 143 P-PQGGNKPQGPPPPGKPQG 161 Score = 46.6 bits (109), Expect = 1e-05 Identities = 41/123 (33%), Positives = 49/123 (39%), Gaps = 20/123 (16%) Query: 9 EGYRLVQRPPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGA--PLGPPPPRQPGALAYGA 66 E L+ P A G + + P + PG G P+G P GPPPP PG Sbjct: 27 ESPSLIAGNPQGAPPQGGN--KPQGPPSPPGKPQGPPPQGGNQPQGPPPP--PGKPQ--- 79 Query: 67 FGPPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAA----APPNAPGGPPGPQPAPSAAAP 122 GPP P PPP +P P G + +PP P GPP PQ P Sbjct: 80 -GPPPQGGNKPQGPPPPG-----KPQGPPPQGDKSRSPRSPPGKPQGPP-PQGGNQPQGP 132 Query: 123 PPP 125 PPP Sbjct: 133 PPP 135 Score = 46.6 bits (109), Expect = 1e-05 Identities = 42/139 (30%), Positives = 46/139 (33%), Gaps = 37/139 (26%) Query: 9 EGYRLVQRPPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFG 68 +G Q PP GP PP S P G P GPPP Q G G Sbjct: 207 QGGNKPQGPPPPGKPQGP------PPQGDNKSQSARSPPGKPQGPPP--QGGNQPQGPPP 258 Query: 69 PPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPP-----------NAPG--------- 108 PP P PPP G +P P PG+ PP + PG Sbjct: 259 PPGK----PQGPPPQGGN---KPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQG 311 Query: 109 --GPPGPQPAPSAAAPPPP 125 P GP P P PPP Sbjct: 312 GNQPQGPPPPPGKPQGPPP 330 Score = 45.1 bits (105), Expect = 4e-05 Identities = 32/97 (32%), Positives = 37/97 (38%), Gaps = 6/97 (6%) Query: 33 PPYAGPGLDSGLRPRGAPLGPPPP----RQPGALAYGAFGPPSSFQPFPAVPPPAAGIAH 88 PP G G P G P GPPP R P + GPP P PPP G Sbjct: 81 PPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 140 Query: 89 LQPVATPYPGRAAAPPNAPGGPP--GPQPAPSAAAPP 123 P + PP P GPP G + S+ +PP Sbjct: 141 GPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPP 177 Score = 45.1 bits (105), Expect = 4e-05 Identities = 35/91 (38%), Positives = 38/91 (41%), Gaps = 11/91 (12%) Query: 33 PPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPAV-------PPPAAG 85 PP G G P G P GPPP Q G+ + A PP Q P PPP AG Sbjct: 328 PPPQGGNKPQGPPPPGKPQGPPP--QGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAG 385 Query: 86 IAHLQPVATPYPGRAAAPPNAP-GGPPGPQP 115 QP A P G+ PP P GG P P Sbjct: 386 GNPQQPQAPP-AGQPQGPPRPPQGGRPSRPP 415 Score = 39.3 bits (90), Expect = 0.002 Identities = 31/83 (37%), Positives = 31/83 (37%), Gaps = 16/83 (19%) Query: 48 GAPLGPPPPRQPGALAYGAFGPPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAP 107 G P G PP Q G G PP P PPP G QP P PP P Sbjct: 34 GNPQGAPP--QGGNKPQGPPSPPGK----PQGPPPQGGN---QPQGPP------PPPGKP 78 Query: 108 GGPPGPQPAPSAAAPPPPAHALG 130 GPP PQ PPPP G Sbjct: 79 QGPP-PQGGNKPQGPPPPGKPQG 100 >gi|11386197 forkhead box E3 [Homo sapiens] Length = 319 Score = 51.6 bits (122), Expect = 4e-07 Identities = 47/134 (35%), Positives = 53/134 (39%), Gaps = 17/134 (12%) Query: 11 YRLVQRPPSAAAAHGPHALRTLPPYA-GPGLDSGLRPRGAPLGPPPPR-----------Q 58 ++ + P AAAA GP PYA PG + P A GP PP Q Sbjct: 167 FKRAELPAHAAAAPGPPLPFPYAPYAPAPGPALLVPPPSAGPGPSPPARLFSVDSLVNLQ 226 Query: 59 PGALAYGAFGPPSSFQPFPAVP--PPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPA 116 P GA PP P A PP A A P+ + P R P PG PGP PA Sbjct: 227 PELAGLGAPEPPCCAAPDAAAAAFPPCAAAAS-PPLYSQVPDRLVLPATRPG--PGPLPA 283 Query: 117 PSAAAPPPPAHALG 130 A PA ALG Sbjct: 284 EPLLALAGPAAALG 297 Score = 35.8 bits (81), Expect = 0.021 Identities = 19/49 (38%), Positives = 23/49 (46%) Query: 69 PPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAP 117 PP++F FPA+P A P+A PGR A G P PAP Sbjct: 9 PPAAFSGFPALPAVAPSGPPPSPLAGAEPGREPEEAAAGRGEAAPTPAP 57 Score = 33.1 bits (74), Expect = 0.14 Identities = 20/57 (35%), Positives = 25/57 (43%), Gaps = 4/57 (7%) Query: 97 PGRAAAPPNAP----GGPPGPQPAPSAAAPPPPAHALGGMDAELIDEEALTSLELEL 149 P AAA P P P P P P+ PPP A A L ++L +L+ EL Sbjct: 173 PAHAAAAPGPPLPFPYAPYAPAPGPALLVPPPSAGPGPSPPARLFSVDSLVNLQPEL 229 Score = 32.3 bits (72), Expect = 0.24 Identities = 26/79 (32%), Positives = 28/79 (35%), Gaps = 14/79 (17%) Query: 33 PPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPAVPPPAAGIAHLQPV 92 PP A G + P AP GPPP GA +P AAG P Sbjct: 9 PPAAFSGFPA--LPAVAPSGPPPSPLAGA------------EPGREPEEAAAGRGEAAPT 54 Query: 93 ATPYPGRAAAPPNAPGGPP 111 P PGR P G PP Sbjct: 55 PAPGPGRRRRRPLQRGKPP 73 Score = 30.4 bits (67), Expect = 0.90 Identities = 41/122 (33%), Positives = 48/122 (39%), Gaps = 36/122 (29%) Query: 31 TLPPYAGPGLDSG--LRPRGAPLGPPPPRQPGALAYGAFGPPSSF-------QPFPA--V 79 TL P A D+G LR R P A A A GPP F P PA V Sbjct: 146 TLDPAAADMFDNGSFLRRRKRFKRAELP----AHAAAAPGPPLPFPYAPYAPAPGPALLV 201 Query: 80 PPPAAG--------------IAHLQP----VATPYPGRAAAPPNAPGGPPGPQPAPSAAA 121 PPP+AG + +LQP + P P AAP A P P +AA+ Sbjct: 202 PPPSAGPGPSPPARLFSVDSLVNLQPELAGLGAPEPPCCAAPDAAAAAFP---PCAAAAS 258 Query: 122 PP 123 PP Sbjct: 259 PP 260 Score = 28.1 bits (61), Expect = 4.5 Identities = 20/50 (40%), Positives = 24/50 (48%), Gaps = 6/50 (12%) Query: 84 AGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAAAPP--PPAHALGG 131 AG + + P A + G A P AP GPP P+P A A P P A G Sbjct: 2 AGRSDMDPPAA-FSGFPALPAVAPSGPP---PSPLAGAEPGREPEEAAAG 47 Score = 26.9 bits (58), Expect = 9.9 Identities = 23/73 (31%), Positives = 30/73 (41%), Gaps = 3/73 (4%) Query: 17 PPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYG---AFGPPSSF 73 P +AAAA P A PP D + P P P P +P G A GP S Sbjct: 243 PDAAAAAFPPCAAAASPPLYSQVPDRLVLPATRPGPGPLPAEPLLALAGPAAALGPLSPG 302 Query: 74 QPFPAVPPPAAGI 86 + + P A+G+ Sbjct: 303 EAYLRQPGFASGL 315 >gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo sapiens] Length = 309 Score = 51.6 bits (122), Expect = 4e-07 Identities = 42/127 (33%), Positives = 45/127 (35%), Gaps = 28/127 (22%) Query: 17 PPSAAAAHGPHALRTLPPYAG---------PGLDSGLRPRGAPLGPPPPRQPGALAYGAF 67 PP GP PP G PG G P+G PP +PG Sbjct: 177 PPHPGKPEGP------PPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPE---- 226 Query: 68 GPPSSFQPFPAVPPPAAGIAH-------LQPVATPYPGRAAAPPNAPGGP--PGPQPAPS 118 GPPS P PPP G +P P PGR PP G P P P PA Sbjct: 227 GPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGK 286 Query: 119 AAAPPPP 125 PPPP Sbjct: 287 PQGPPPP 293 Score = 45.4 bits (106), Expect = 3e-05 Identities = 37/112 (33%), Positives = 43/112 (38%), Gaps = 13/112 (11%) Query: 16 RPPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQP 75 +P G RT PP PG G P+G PP +PG GPP Sbjct: 35 KPEGRRPQGGNQPQRTPPP---PGKPEGRPPQGGNQSQGPPPRPGK----PEGPPPQGGN 87 Query: 76 FPAVPPPAAGIAHLQPVATPYPG-RAAAPPNAPGGPPGPQP--APSAAAPPP 124 PPP G QP P G ++ PP PG P GP P + PPP Sbjct: 88 QSQGPPPRPGKPEGQP---PQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPP 136 Score = 45.4 bits (106), Expect = 3e-05 Identities = 37/122 (30%), Positives = 43/122 (35%), Gaps = 25/122 (20%) Query: 17 PPSAAAAHGPHALRTLPPYAG---------PGLDSGLRPRGAPLGPPPPRQPGALAYGAF 67 PP GP PP G PG G P+G PP +PG Sbjct: 72 PPRPGKPEGP------PPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPE---- 121 Query: 68 GPPSSFQPFPAVPPPAAGIAHLQPVATPYPG--RAAAPPNAPGGPPGPQPAPSAAAPPPP 125 GPP PPP G +P P G ++ PP PG P GP P + PP Sbjct: 122 GPPPQGGNQSQGPPPRPG----KPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPP 177 Query: 126 AH 127 H Sbjct: 178 PH 179 Score = 40.8 bits (94), Expect = 7e-04 Identities = 36/114 (31%), Positives = 43/114 (37%), Gaps = 20/114 (17%) Query: 15 QRPPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQ 74 Q P + GP PP PG G P+G PP +PG GPP Sbjct: 102 QPPQGGNQSQGP------PPR--PGKPEGPPPQGGNQSQGPPPRPGKPE----GPPPQGG 149 Query: 75 PFPAVPPPAAGIAHLQPVATPYPG--RAAAPPNAPGGPPGPQP--APSAAAPPP 124 PPP G +P P G ++ PP PG P GP P + PPP Sbjct: 150 NQSQGPPPRPG----KPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPP 199 Score = 34.3 bits (77), Expect = 0.062 Identities = 26/83 (31%), Positives = 29/83 (34%), Gaps = 19/83 (22%) Query: 17 PPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPP----RQPGALAYGAFGPPSS 72 PP GP P P P G P GPPPP +QP PP + Sbjct: 240 PPHPGKPQGPPPQEGNKPQRPP-------PPGRPQGPPPPGGNPQQPL--------PPPA 284 Query: 73 FQPFPAVPPPAAGIAHLQPVATP 95 +P PPP G H P P Sbjct: 285 GKPQGPPPPPQGGRPHRPPQGQP 307 Score = 33.1 bits (74), Expect = 0.14 Identities = 19/46 (41%), Positives = 19/46 (41%), Gaps = 6/46 (13%) Query: 15 QRPPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPG 60 QRPP GP PP G P G P GPPPP Q G Sbjct: 258 QRPPPPGRPQGP------PPPGGNPQQPLPPPAGKPQGPPPPPQGG 297 Score = 32.7 bits (73), Expect = 0.18 Identities = 32/101 (31%), Positives = 33/101 (32%), Gaps = 22/101 (21%) Query: 33 PPYAGPGLDSGLRPR-GAPLGPP---------PPRQPGALAYGAFGPPSSFQPFPAVPPP 82 PP G G PR G P GPP PP PG GPP P PPP Sbjct: 207 PPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQ----GPPPQEGNKPQRPPP 262 Query: 83 AA--------GIAHLQPVATPYPGRAAAPPNAPGGPPGPQP 115 G QP+ P PP GG P P Sbjct: 263 PGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPP 303 Score = 27.7 bits (60), Expect = 5.8 Identities = 15/44 (34%), Positives = 16/44 (36%), Gaps = 8/44 (18%) Query: 90 QPVATPYPGRAAAPPNAPGGPP--------GPQPAPSAAAPPPP 125 +P P R PP P G P GP P P PPP Sbjct: 40 RPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPP 83 >gi|153792074 proline rich 12 [Homo sapiens] Length = 2036 Score = 51.6 bits (122), Expect = 4e-07 Identities = 48/132 (36%), Positives = 51/132 (38%), Gaps = 13/132 (9%) Query: 17 PPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGP-----PPPRQPGALAYGAFGPPS 71 PP A AA P PP PGL S G P P PPP P A PP Sbjct: 1422 PPLAPAAAVPGP----PPL--PGLPSA-NSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPP 1474 Query: 72 SFQPFPAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPS-AAAPPPPAHALG 130 P PA+P P +A P P PP P PP P PA + AAPP A Sbjct: 1475 PPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPS 1534 Query: 131 GMDAELIDEEAL 142 D EL D L Sbjct: 1535 PEDPELPDTRPL 1546 Score = 40.4 bits (93), Expect = 9e-04 Identities = 45/153 (29%), Positives = 57/153 (37%), Gaps = 17/153 (11%) Query: 36 AGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPAVPP-PAAGIAHLQPVAT 94 AGP D G GA GPPP G AY +GP + A P P G+ +P Sbjct: 965 AGPPEDEGDPKAGA--GPPP----GPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPEL 1018 Query: 95 PYPGRAAAPPNAPGGPPGPQPAPSAAAPPPPAHA---LGGMDAELIDEEALTSLELELGL 151 P A GP P P PPPPA A GG+ + + L Sbjct: 1019 PSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSF 1078 Query: 152 H--RVRELP-----ELFLGQSEFDCFSDLGSAP 177 H R R+ P +L+ + EF+ D P Sbjct: 1079 HLLRRRDPPFQTPKKLYAQEYEFEADEDKADVP 1111 Score = 39.7 bits (91), Expect = 0.001 Identities = 32/101 (31%), Positives = 40/101 (39%), Gaps = 10/101 (9%) Query: 48 GAPLGPPPP-----RQPGALAYGAFGPPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAA 102 GA GPPPP RQ + + + P+S QP P PPPA + H YP Sbjct: 270 GAAPGPPPPERALPRQDTVIKH--YQRPASAQP-PPPPPPAHALQHYLSCGGSYPSMGHR 326 Query: 103 PPNAPGGPPGPQPAPSAAAPPP--PAHALGGMDAELIDEEA 141 A G +P+P A P P+ A G EA Sbjct: 327 ANLACSPLGGGEPSPGAGEPSKAGPSGATAGASGRATGPEA 367 Score = 38.5 bits (88), Expect = 0.003 Identities = 35/98 (35%), Positives = 38/98 (38%), Gaps = 24/98 (24%) Query: 33 PPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPAVPPPAAGIAHLQPV 92 PP AGP S P G PL P A GPP P P +P + P+ Sbjct: 1408 PPLAGPKDTS--TPDGPPLAP---------AAAVPGPP----PLPGLPSANSNGTPEPPL 1452 Query: 93 ATPYPGRAAAPPNAPGGP-PGPQPAPSAAAPPPPAHAL 129 P PP P P P PQP P PPPP AL Sbjct: 1453 LEEKP-----PPTPPPAPTPQPQPPPP---PPPPQPAL 1482 Score = 37.7 bits (86), Expect = 0.006 Identities = 44/150 (29%), Positives = 58/150 (38%), Gaps = 43/150 (28%) Query: 14 VQRPPSAAAAHG---PHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPP 70 +Q PP + A+G PH + L P P + S L G G L GP Sbjct: 170 LQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGG-------GVLGPAGLGPA 222 Query: 71 SS--FQPFPAVPPPAAGIAHLQP----VATPYPGRAAAPPNAP------GGPPGPQPA-- 116 + ++P P PPP HL +A+ AAA ++P G PGP P Sbjct: 223 QTPPYRPGPPDPPPPP--RHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPER 280 Query: 117 --------------PSAAAPPPP---AHAL 129 P++A PPPP AHAL Sbjct: 281 ALPRQDTVIKHYQRPASAQPPPPPPPAHAL 310 Score = 32.0 bits (71), Expect = 0.31 Identities = 30/107 (28%), Positives = 37/107 (34%), Gaps = 7/107 (6%) Query: 26 PHALRTLPPYAGPGL-DSGLRPRGAPLGPPPPRQ-----PGALAYGAFGPPSSFQPFPAV 79 P L T + G G + G + +P PPP Q P L A GP P Sbjct: 739 PEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPP 798 Query: 80 PPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPG-PQPAPSAAAPPPP 125 P + P +P + P G PQP P PPPP Sbjct: 799 PQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPP 845 Score = 30.4 bits (67), Expect = 0.90 Identities = 26/93 (27%), Positives = 33/93 (35%), Gaps = 11/93 (11%) Query: 44 LRPRGAPLGPPPPRQPGALAYGAFGPPSS-------FQPFPAVPPPAAGIAHLQ----PV 92 L P G PP G GA+ PS F P ++ P + + + P Sbjct: 890 LPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPT 949 Query: 93 ATPYPGRAAAPPNAPGGPPGPQPAPSAAAPPPP 125 G AA GPP + P A A PPP Sbjct: 950 MEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPP 982 Score = 30.4 bits (67), Expect = 0.90 Identities = 22/62 (35%), Positives = 26/62 (41%), Gaps = 15/62 (24%) Query: 77 PAVPPPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQP------------APSAAAPPP 124 P VP +G A PV+ G +A PP AP PP P+ P A P P Sbjct: 1670 PPVPVRRSGQAK-NPVSAG--GSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEP 1726 Query: 125 PA 126 PA Sbjct: 1727 PA 1728 Score = 29.3 bits (64), Expect = 2.0 Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 6/64 (9%) Query: 81 PPAAGIAHLQPVATPYPGRAAAPPNAPGGPPGPQPAPSAAAP-PPPAHALG-GMDAELID 138 PP P++ P + PP+ P PQP + A P PPP+ A G G E + Sbjct: 1296 PPLYQAGLTPPLSPP----KSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAE 1351 Query: 139 EEAL 142 E L Sbjct: 1352 SEGL 1355 Score = 28.5 bits (62), Expect = 3.4 Identities = 32/121 (26%), Positives = 40/121 (33%), Gaps = 7/121 (5%) Query: 10 GYRLVQRPPSAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGP 69 GYR + + P G + P S P+ LG P A GA G Sbjct: 379 GYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGA 438 Query: 70 P----SSFQPFPAVPPPAAGIAHLQPVA---TPYPGRAAAPPNAPGGPPGPQPAPSAAAP 122 S QP + P A G A + P + PP P GPP P A + Sbjct: 439 GGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYS 498 Query: 123 P 123 P Sbjct: 499 P 499 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.138 0.442 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,023,358 Number of Sequences: 37866 Number of extensions: 1116075 Number of successful extensions: 25916 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 1024 Number of HSP's successfully gapped in prelim test: 1627 Number of HSP's that attempted gapping in prelim test: 7734 Number of HSP's gapped (non-prelim): 10906 length of query: 184 length of database: 18,247,518 effective HSP length: 96 effective length of query: 88 effective length of database: 14,612,382 effective search space: 1285889616 effective search space used: 1285889616 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.