Guide to the Human Genome
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Search of human proteins with 190358499

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|190358499 hypothetical protein LOC55435 isoform a [Homo
sapiens]
         (302 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|190358499 hypothetical protein LOC55435 isoform a [Homo sapiens]   609   e-175
gi|190358501 hypothetical protein LOC55435 isoform b [Homo sapiens]   534   e-152
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     42   9e-04
gi|78042577 MAP7 domain containing 1 [Homo sapiens]                    42   9e-04
gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens]     41   0.001
gi|28269672 serologically defined colon cancer antigen 8 [Homo s...    41   0.001
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...    41   0.001
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof...    40   0.002
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof...    40   0.002
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             40   0.002
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m...    40   0.003
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m...    40   0.003
gi|161702986 ezrin [Homo sapiens]                                      40   0.003
gi|21614499 ezrin [Homo sapiens]                                       40   0.003
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof...    40   0.003
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof...    40   0.003
gi|13027602 DDRGK domain containing 1 [Homo sapiens]                   40   0.003
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]           39   0.004
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]           39   0.004
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]           39   0.004
gi|120953300 leucine-rich repeats and IQ motif containing 1 isof...    39   0.004
gi|45439327 periplakin [Homo sapiens]                                  39   0.004
gi|120953243 leucine-rich repeats and IQ motif containing 1 isof...    39   0.004
gi|148746195 trichohyalin [Homo sapiens]                               39   0.006
gi|4758648 kinesin family member 5B [Homo sapiens]                     39   0.007
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi...    38   0.010
gi|64276486 serologically defined colon cancer antigen 10 [Homo ...    38   0.010
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]    38   0.010
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]    38   0.010
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    38   0.013

>gi|190358499 hypothetical protein LOC55435 isoform a [Homo sapiens]
          Length = 302

 Score =  609 bits (1571), Expect = e-175
 Identities = 302/302 (100%), Positives = 302/302 (100%)

Query: 1   MGNCCWTQCFGLLRKEAGRLQRVGGGGGSKYFRTCSRGEHLTIEFENLVESDEGESPGSS 60
           MGNCCWTQCFGLLRKEAGRLQRVGGGGGSKYFRTCSRGEHLTIEFENLVESDEGESPGSS
Sbjct: 1   MGNCCWTQCFGLLRKEAGRLQRVGGGGGSKYFRTCSRGEHLTIEFENLVESDEGESPGSS 60

Query: 61  HRPLTEEEIVDLRERHYDSIAEKQKDLDKKIQKELALQEEKLRLEEEALYAAQREAARAA 120
           HRPLTEEEIVDLRERHYDSIAEKQKDLDKKIQKELALQEEKLRLEEEALYAAQREAARAA
Sbjct: 61  HRPLTEEEIVDLRERHYDSIAEKQKDLDKKIQKELALQEEKLRLEEEALYAAQREAARAA 120

Query: 121 KQRKLLEQERQRIVQQYHPSNNGEYQSSGPEDDFESCLRNMKSQYEVFRSSRLSSDATVL 180
           KQRKLLEQERQRIVQQYHPSNNGEYQSSGPEDDFESCLRNMKSQYEVFRSSRLSSDATVL
Sbjct: 121 KQRKLLEQERQRIVQQYHPSNNGEYQSSGPEDDFESCLRNMKSQYEVFRSSRLSSDATVL 180

Query: 181 TPNTESSCDLMTKTKSTSGNDDSTSLDLEWEDEEGMNRMLPMRERSKTEEDILRAALKYS 240
           TPNTESSCDLMTKTKSTSGNDDSTSLDLEWEDEEGMNRMLPMRERSKTEEDILRAALKYS
Sbjct: 181 TPNTESSCDLMTKTKSTSGNDDSTSLDLEWEDEEGMNRMLPMRERSKTEEDILRAALKYS 240

Query: 241 NKKTGSNPTSASDDSNGLEWENDFVSAEMDDNGNSEYSGFVNPVLELSDSGIRHSDTDQQ 300
           NKKTGSNPTSASDDSNGLEWENDFVSAEMDDNGNSEYSGFVNPVLELSDSGIRHSDTDQQ
Sbjct: 241 NKKTGSNPTSASDDSNGLEWENDFVSAEMDDNGNSEYSGFVNPVLELSDSGIRHSDTDQQ 300

Query: 301 TR 302
           TR
Sbjct: 301 TR 302


>gi|190358501 hypothetical protein LOC55435 isoform b [Homo sapiens]
          Length = 269

 Score =  534 bits (1375), Expect = e-152
 Identities = 269/302 (89%), Positives = 269/302 (89%), Gaps = 33/302 (10%)

Query: 1   MGNCCWTQCFGLLRKEAGRLQRVGGGGGSKYFRTCSRGEHLTIEFENLVESDEGESPGSS 60
           MGNCCWTQCFGLLRKEAGRLQRVGGGGGSKYFRTCSRGEHLTIEFENLVESDEGESPGSS
Sbjct: 1   MGNCCWTQCFGLLRKEAGRLQRVGGGGGSKYFRTCSRGEHLTIEFENLVESDEGESPGSS 60

Query: 61  HRPLTEEEIVDLRERHYDSIAEKQKDLDKKIQKELALQEEKLRLEEEALYAAQREAARAA 120
           HRPLTEEEIVDLRERHYDSIAEKQKDLDKKIQK                           
Sbjct: 61  HRPLTEEEIVDLRERHYDSIAEKQKDLDKKIQK--------------------------- 93

Query: 121 KQRKLLEQERQRIVQQYHPSNNGEYQSSGPEDDFESCLRNMKSQYEVFRSSRLSSDATVL 180
                 EQERQRIVQQYHPSNNGEYQSSGPEDDFESCLRNMKSQYEVFRSSRLSSDATVL
Sbjct: 94  ------EQERQRIVQQYHPSNNGEYQSSGPEDDFESCLRNMKSQYEVFRSSRLSSDATVL 147

Query: 181 TPNTESSCDLMTKTKSTSGNDDSTSLDLEWEDEEGMNRMLPMRERSKTEEDILRAALKYS 240
           TPNTESSCDLMTKTKSTSGNDDSTSLDLEWEDEEGMNRMLPMRERSKTEEDILRAALKYS
Sbjct: 148 TPNTESSCDLMTKTKSTSGNDDSTSLDLEWEDEEGMNRMLPMRERSKTEEDILRAALKYS 207

Query: 241 NKKTGSNPTSASDDSNGLEWENDFVSAEMDDNGNSEYSGFVNPVLELSDSGIRHSDTDQQ 300
           NKKTGSNPTSASDDSNGLEWENDFVSAEMDDNGNSEYSGFVNPVLELSDSGIRHSDTDQQ
Sbjct: 208 NKKTGSNPTSASDDSNGLEWENDFVSAEMDDNGNSEYSGFVNPVLELSDSGIRHSDTDQQ 267

Query: 301 TR 302
           TR
Sbjct: 268 TR 269


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 41.6 bits (96), Expect = 9e-04
 Identities = 40/173 (23%), Positives = 83/173 (47%), Gaps = 29/173 (16%)

Query: 65  TEEEIVDLRERHYDSIAEKQKDLDKKIQKELALQEEKLRLEEEALYAAQREAARAAKQRK 124
           +EE+I  L++ H   +A K+++L KK+Q      +E++++   AL  +Q E  + ++++ 
Sbjct: 474 SEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKV---ALEKSQSEYLKISQEK- 529

Query: 125 LLEQERQRIVQQYHPSNNGEYQSSGPEDDFESCLRNMKSQYEVFRSSRLSSDATV---LT 181
             EQ+    +++       E Q      + E+ LR+++ + E +R+  L  ++++   L 
Sbjct: 530 --EQQESLALEEL------ELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQ 581

Query: 182 PNTESSCDLMTKTKSTSGNDDSTSLDLEWEDEEGMNRMLPMRERSKTEEDILR 234
            N   S DL              ++ LE E  +    +  M E+ KTE + L+
Sbjct: 582 ENKNQSKDL--------------AVHLEAEKNKHNKEITVMVEKHKTELESLK 620


>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
          Length = 841

 Score = 41.6 bits (96), Expect = 9e-04
 Identities = 30/89 (33%), Positives = 46/89 (51%), Gaps = 15/89 (16%)

Query: 59  SSHRPLTEEEIVDLRERHYDS----------IAEK-----QKDLDKKIQKELALQEEKLR 103
           +S  P T++E+    ERH  +          +A K     +K+   K  +E  LQE + R
Sbjct: 122 ASDSPPTKQEVKKAGERHKLAKERREERAKYLAAKKAVWLEKEEKAKALREKQLQERRRR 181

Query: 104 LEEEALYAAQREAARAAKQRKLLEQERQR 132
           LEE+ L A QR AA   +QR+ LE+ ++R
Sbjct: 182 LEEQRLKAEQRRAALEERQRQKLEKNKER 210



 Score = 28.9 bits (63), Expect = 5.8
 Identities = 31/129 (24%), Positives = 56/129 (43%), Gaps = 10/129 (7%)

Query: 50  ESDEGESPGSSHRPLTEEEIVDLRERHYDSIAE-KQKDLDKKIQKELALQEEKLRLEEEA 108
           E  E        + + EE++    E   +  AE ++++  +  +K  A QEE+ RL++  
Sbjct: 617 EEQERRLQAERDKRMREEQLAREAEARAEREAEARRREEQEAREKAQAEQEEQERLQK-- 674

Query: 109 LYAAQREAARAAKQRKLLEQERQRIVQQYHPSNNGEYQSSGPEDDFESCLRNMKSQYEVF 168
               Q+E A A   R   E ERQR+ ++ H     + +    +   E   R  KS+    
Sbjct: 675 ----QKEEAEA---RSREEAERQRLEREKHFQQQEQERQERRKRLEEIMKRTRKSEVSET 727

Query: 169 RSSRLSSDA 177
           +  + S +A
Sbjct: 728 KQKQDSKEA 736


>gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens]
          Length = 543

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 63/268 (23%), Positives = 109/268 (40%), Gaps = 38/268 (14%)

Query: 39  EHLTIEFENLVESDEGESPGSSHRPLTEEEIVDLRERHYDSIAEKQ------KDLDKKIQ 92
           ++  +E E LV   +   P S  R L E+EI DLR    D+  EKQ      + L++ ++
Sbjct: 114 QNKVLEAELLVLRQKHSEP-SRFRALYEQEIRDLRLAAEDATNEKQALQGEREGLEETLR 172

Query: 93  KELALQEEKLRLEEEA---LYAAQREAARAAKQRKLLEQ------ERQRIVQQYHPSNNG 143
              A  EE++   E+A   L  A++ A  AA  R  LE+      +    +++ H     
Sbjct: 173 NLQARYEEEVLSREDAEGRLMEARKGADEAALARAELEKRIDSLMDEISFLKKVHEEEIA 232

Query: 144 EYQS-----------SGPEDDFESCLRNMKSQYEVFRSSRL-------SSDATVLTPNTE 185
           E Q+              + D  + L+++++QYE   +  +        S  TVLT +  
Sbjct: 233 ELQAQIQYAQISVEMDVTKPDLSAALKDIRAQYEKLAAKNMQNAEEWFKSRFTVLTESAA 292

Query: 186 SSCDLMTKTKSTSGNDDS--TSLDLEWEDEEGMNRML--PMRERSKTEEDILRAALKYSN 241
            + D +   K           +  LE E   GMN  L   ++E    +   + A     N
Sbjct: 293 KNTDAVRAAKDEVSESRRLLKAKTLEIEACRGMNEALEKQLQELEDKQNADISAMQDTIN 352

Query: 242 KKTGSNPTSASDDSNGLEWENDFVSAEM 269
           K      T+ S+ +  L+   D ++ +M
Sbjct: 353 KLENELRTTKSEMARYLKEYQDLLNVKM 380



 Score = 32.0 bits (71), Expect = 0.69
 Identities = 22/90 (24%), Positives = 44/90 (48%), Gaps = 1/90 (1%)

Query: 91  IQKELALQEEKLRLEEEALYAAQREAARAAKQRKLLEQERQRIVQQYHPSNNGEYQSSGP 150
           I++   L+++   LE E L   Q+ +   ++ R L EQE + +      + N +    G 
Sbjct: 105 IERVHELEQQNKVLEAELLVLRQKHS-EPSRFRALYEQEIRDLRLAAEDATNEKQALQGE 163

Query: 151 EDDFESCLRNMKSQYEVFRSSRLSSDATVL 180
            +  E  LRN++++YE    SR  ++  ++
Sbjct: 164 REGLEETLRNLQARYEEEVLSREDAEGRLM 193


>gi|28269672 serologically defined colon cancer antigen 8 [Homo
           sapiens]
          Length = 713

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 41/191 (21%), Positives = 81/191 (42%), Gaps = 17/191 (8%)

Query: 49  VESDEGESPGSSHRPLTEEEIVDLRERHYDSIA----EKQKDLDKKIQKELALQEEKLRL 104
           +E DE E      R  T  ++ +++++  + +     E ++ L+++ QK    +EE LRL
Sbjct: 466 MEKDEAEKEHREFRAKTNRDL-EIKDQEIEKLRIELDESKQHLEQEQQKAALAREECLRL 524

Query: 105 EEEALYAAQREAARAAKQRKLLEQERQRIVQQYHPSNNGE-YQSSGPEDDFESCLRNMKS 163
            E            +  Q  L  QE+  I Q +      +  Q+   E +    ++ M++
Sbjct: 525 TE--------LLGESEHQLHLTRQEKDSIQQSFSKEAKAQALQAQQREQELTQKIQQMEA 576

Query: 164 QYEVFRSSR---LSSDATVLTPNTESSCDLMTKTKSTSGNDDSTSLDLEWEDEEGMNRML 220
           Q++   + +   L+S  T LT   E  C L  K +  S    S    L  E     +++ 
Sbjct: 577 QHDKTENEQYLLLTSQNTFLTKLKEECCTLAKKLEQISQKTRSEIAQLSQEKRYTYDKLG 636

Query: 221 PMRERSKTEED 231
            ++ R++  E+
Sbjct: 637 KLQRRNEELEE 647


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
           sapiens]
          Length = 570

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 34/169 (20%), Positives = 75/169 (44%), Gaps = 6/169 (3%)

Query: 66  EEEIVDLRERHYDSIAEKQKDLDKKIQKELALQEEKLRLEEEALYAAQREAARAAKQRKL 125
           EE+I +L E+ ++   EK ++ ++K Q+E  ++E++ R E+EA    Q E  R  +Q + 
Sbjct: 343 EEKIRELEEKMHEQ--EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR--EQEEK 398

Query: 126 LEQERQRIVQQYHPSNNGEYQSSGPEDDFESCLRNMKSQYEVFRSSRLSSDATVLTPNTE 185
           + ++ + + +Q       E +    E++ +     M+ Q E  R                
Sbjct: 399 IREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQ--EKKIREQEEKIR 456

Query: 186 SSCDLMTKTKSTSGNDDSTSLDLEWEDEEGMNRMLPMRERSKTEEDILR 234
              ++M + +   G  +    + E + +E   +M    E+ + +E  +R
Sbjct: 457 EQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIR 505



 Score = 35.0 bits (79), Expect = 0.081
 Identities = 29/156 (18%), Positives = 66/156 (42%), Gaps = 4/156 (2%)

Query: 82  EKQKDLDKKIQKE---LALQEEKLRLEEEALYAAQREAARAAKQRKLLEQERQRIVQQYH 138
           EK ++ ++KIQ++   +  QEEK+R +EE ++  + +  R  +     E++ + + ++ H
Sbjct: 295 EKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH 354

Query: 139 PSNNGEYQSSGPEDDFESCLRNMKSQYEVFRSSRLSSDATVLTPNTESSCDLMTKTKSTS 198
                  Q    +++ E      K Q +  +  R                ++M + +   
Sbjct: 355 EQEKIREQEEKRQEE-EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKM 413

Query: 199 GNDDSTSLDLEWEDEEGMNRMLPMRERSKTEEDILR 234
           G  +    + E E +E   +M    E+ + +E  +R
Sbjct: 414 GEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIR 449



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 24/93 (25%), Positives = 47/93 (50%), Gaps = 6/93 (6%)

Query: 44  EFENLVESDEGESPGSSHRPLTEEEIVDLRERHYDSIAEKQKDLDKKIQKELALQEEKLR 103
           E E +++  E +      +   +EE +  +E       EK ++ +KKI++    QEEK+R
Sbjct: 401 EQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIRE----QEEKIR 456

Query: 104 LEEEALYAAQREAARAAKQRKLLEQERQRIVQQ 136
            +EE +   ++E     ++ K+ EQE +   Q+
Sbjct: 457 EQEEMM--QEQEEKMGEQEGKMCEQEAKMQEQE 487



 Score = 30.8 bits (68), Expect = 1.5
 Identities = 22/93 (23%), Positives = 48/93 (51%), Gaps = 6/93 (6%)

Query: 44  EFENLVESDEGESPGSSHRPLTEEEIVDLRERHYDSIAEKQKDLDKKIQKELALQEEKLR 103
           E E +++  E E  G     + E+E    + +  +    +Q++  ++ +K++  QEEK+R
Sbjct: 457 EQEEMMQEQE-EKMGEQEGKMCEQEA---KMQEQEEKMRRQEEKIREQEKKIREQEEKIR 512

Query: 104 LEEEALYAAQREAARAAKQRKLLEQERQRIVQQ 136
            +EE +   ++E     ++ K+ EQE +   Q+
Sbjct: 513 EQEEMM--QEQEEKMWEQEEKMCEQEEKMQEQE 543



 Score = 28.1 bits (61), Expect = 10.0
 Identities = 20/96 (20%), Positives = 45/96 (46%), Gaps = 2/96 (2%)

Query: 39  EHLTIEFENLVESDEGESPGSSHRPLTEEEIVDLRERHYDSIAEKQKDLDKKI--QKELA 96
           E +  E E  +   EG+      +   +EE +  +E       +K ++ ++KI  Q+E+ 
Sbjct: 459 EEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 518

Query: 97  LQEEKLRLEEEALYAAQREAARAAKQRKLLEQERQR 132
            ++E+   E+E     Q E  +  +++   ++E+ R
Sbjct: 519 QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMR 554


>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           5 [Homo sapiens]
          Length = 748

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 50/248 (20%), Positives = 97/248 (39%), Gaps = 42/248 (16%)

Query: 58  GSSHRPLTEEEIV-DLRERHYDSIAEKQKDLDKKIQKELALQ------------------ 98
           G  H  + E+E   + R+RH +   + +++ +++ ++E+A +                  
Sbjct: 84  GGKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRER 143

Query: 99  EEKLRLEEEALYAAQREAARAAKQRKLLEQERQRIVQQYHPSNNGEYQSS---------- 148
           E K+R E++     Q+E  R A++R+  E+E +R V  +H +   +Y             
Sbjct: 144 ERKMR-EQQKEQREQKERERRAEERR-KEREARREVSAHHRTMREDYSDKVKASHWSRSP 201

Query: 149 --GPEDDFESCLRNMKSQYEVFRSSRLSSDATVLTPNTESSCDLMTKTKSTSGNDDSTSL 206
              P + FE        + E      L SD   ++ +   +    + +  +    +    
Sbjct: 202 PRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEE 261

Query: 207 DLEWEDEEGMNRMLPMRERSKTEEDILRAALKYSNKKTGSNPTSASDDSNGLEWENDFVS 266
           + E E+EEG        E  + EE+          ++TGSN   AS+ S     E +   
Sbjct: 262 EEEEEEEEGSTSEESEEEEEEEEEE---------EEETGSNSEEASEQSAEEVSEEEMSE 312

Query: 267 AEMDDNGN 274
            E  +N N
Sbjct: 313 DEERENEN 320


>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           2 [Homo sapiens]
          Length = 782

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 50/248 (20%), Positives = 97/248 (39%), Gaps = 42/248 (16%)

Query: 58  GSSHRPLTEEEIV-DLRERHYDSIAEKQKDLDKKIQKELALQ------------------ 98
           G  H  + E+E   + R+RH +   + +++ +++ ++E+A +                  
Sbjct: 118 GGKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRER 177

Query: 99  EEKLRLEEEALYAAQREAARAAKQRKLLEQERQRIVQQYHPSNNGEYQSS---------- 148
           E K+R E++     Q+E  R A++R+  E+E +R V  +H +   +Y             
Sbjct: 178 ERKMR-EQQKEQREQKERERRAEERR-KEREARREVSAHHRTMREDYSDKVKASHWSRSP 235

Query: 149 --GPEDDFESCLRNMKSQYEVFRSSRLSSDATVLTPNTESSCDLMTKTKSTSGNDDSTSL 206
              P + FE        + E      L SD   ++ +   +    + +  +    +    
Sbjct: 236 PRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEE 295

Query: 207 DLEWEDEEGMNRMLPMRERSKTEEDILRAALKYSNKKTGSNPTSASDDSNGLEWENDFVS 266
           + E E+EEG        E  + EE+          ++TGSN   AS+ S     E +   
Sbjct: 296 EEEEEEEEGSTSEESEEEEEEEEEE---------EEETGSNSEEASEQSAEEVSEEEMSE 346

Query: 267 AEMDDNGN 274
            E  +N N
Sbjct: 347 DEERENEN 354


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 31/139 (22%), Positives = 66/139 (47%), Gaps = 5/139 (3%)

Query: 66  EEEIVDLRERHYDSIAEKQKDLDKKIQKELALQEEKLRLEEEAL---YAAQREAARAAKQ 122
           E+E    RE+  +   EK+K+L+K+ +K+  +++E+ + +E+ L      ++E  +  +Q
Sbjct: 524 EQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQ 583

Query: 123 RK--LLEQERQRIVQQYHPSNNGEYQSSGPEDDFESCLRNMKSQYEVFRSSRLSSDATVL 180
            K   LE+ER+++ ++  P           ++   SC +  +  +    S+R   +AT +
Sbjct: 584 EKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPV 643

Query: 181 TPNTESSCDLMTKTKSTSG 199
              TE       +    SG
Sbjct: 644 VHETEPESGSQPRPAVLSG 662



 Score = 36.6 bits (83), Expect = 0.028
 Identities = 37/157 (23%), Positives = 64/157 (40%), Gaps = 19/157 (12%)

Query: 71  DLRERHYDSIAEKQKDLDKKIQKELALQEEKLR-------LEEEALYAAQREAARAAKQR 123
           ++RER  +   E++K+L+K+ ++E   + EK R        E E     QRE  +  KQ 
Sbjct: 503 EIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQE 562

Query: 124 KLLEQERQRIVQQYHPSNNGEYQSSGPEDDFESCLRNMKSQYEVFRSSRLSSDATVLTPN 183
           K  E ERQ+           E Q    ++      +  +   E       + +  V    
Sbjct: 563 KEKELERQK-------EKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQE 615

Query: 184 TESSCD-----LMTKTKSTSGNDDSTSLDLEWEDEEG 215
           +E+SC+     + T+  S     ++T +  E E E G
Sbjct: 616 SENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESG 652



 Score = 32.3 bits (72), Expect = 0.53
 Identities = 51/217 (23%), Positives = 82/217 (37%), Gaps = 27/217 (12%)

Query: 62  RPLTEEEIVDLRERHYDSIAEKQKDLDKK--IQKELALQEEKLRLEEEALYAAQREAARA 119
           R   EEE   + E+   + AEK K LD+K  I ++    EE    E E     ++E  + 
Sbjct: 463 RKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKE 522

Query: 120 AKQRKLLEQERQRIVQQYHPSNNGEYQSSGPEDDFESCLRNMKSQYEVFRSSRLSSDATV 179
            +Q +  E+E+ R  QQ       + Q    E + E   R  + + E+ R      +   
Sbjct: 523 QEQEREKEREKDRERQQEKEKELEKEQEKQREMEKE---RKQEKEKELERQKEKEKELQK 579

Query: 180 LTPNTESSCDLMTKTKSTSGNDDSTSLDLEWEDEEGMNRMLPMRERSKTEEDILRAALKY 239
           +    E  C+L  + +            LE + E     + PM E+ ++E          
Sbjct: 580 M-KEQEKECELEKEREK-----------LEEKIEPREPNLEPMVEKQESENS-------- 619

Query: 240 SNKKTGSNPTSASDDSNGLEWENDFVSAEMDDNGNSE 276
            NK+    P     DSN  E E   V  E +    S+
Sbjct: 620 CNKE--EEPVFTRQDSNRSEKEATPVVHETEPESGSQ 654


>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 37/140 (26%), Positives = 67/140 (47%), Gaps = 8/140 (5%)

Query: 37  RGEHLTIEFENLVESDEGESPGSSHRPLTEEEIVDLRERHYDSIAEKQKDLDKKIQKE-- 94
           R E +  + + + E DE            EE+I +L E   D   EK +++++K+Q+E  
Sbjct: 404 RQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQ-EEKLREVEEKMQEEEE 462

Query: 95  -LALQEEKLRLEEEALYAAQREAARAAKQRKLLEQERQRIVQQYHPSNNGEYQSSGPEDD 153
            +  QEEK++ +EE +   Q +  +  +Q KLL+QE ++I +Q       E +    E+ 
Sbjct: 463 KMQEQEEKIQRQEEKI---QEQEEKTWRQEKLLKQE-EKIWEQEEKMWRQEEKMWEQEEK 518

Query: 154 FESCLRNMKSQYEVFRSSRL 173
            +     M+ Q E  R   +
Sbjct: 519 MQEQEEKMQRQEEKMREQEV 538



 Score = 31.6 bits (70), Expect = 0.90
 Identities = 25/93 (26%), Positives = 46/93 (49%), Gaps = 7/93 (7%)

Query: 46  ENLVESDEGESPGSSHRPLTEEEIVDLRERHYDSI---AEKQKDLDKKI---QKELALQE 99
           E + E DE            EE+I +  E+  + +    +K ++ D+KI   ++E+  QE
Sbjct: 374 EKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQE 433

Query: 100 EKLRLEEEALYAAQREAARAAKQRKLLEQERQR 132
           EK+R E E +   Q E  R  +++   E+E+ +
Sbjct: 434 EKIR-ELEEMMQDQEEKLREVEEKMQEEEEKMQ 465



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 23/100 (23%), Positives = 46/100 (46%), Gaps = 3/100 (3%)

Query: 37  RGEHLTIEFENLVESDEGESPGSSHRPLTEEEIVDLRERHYDSIAEKQKDLDKKIQKELA 96
           R E    E E  +   E +      +   +EE +  +E       EK ++ D+KIQ++  
Sbjct: 329 RQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQ-- 386

Query: 97  LQEEKLRLEEEALYAAQREAARAAKQRKLLEQERQRIVQQ 136
            +EE  R EE+     ++   +  +Q K + ++ ++I +Q
Sbjct: 387 -EEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQ 425



 Score = 30.0 bits (66), Expect = 2.6
 Identities = 21/95 (22%), Positives = 45/95 (47%)

Query: 37  RGEHLTIEFENLVESDEGESPGSSHRPLTEEEIVDLRERHYDSIAEKQKDLDKKIQKELA 96
           R E    E E  +   E +      +   ++E +  +E       EK ++ ++K Q+++ 
Sbjct: 350 RQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMW 409

Query: 97  LQEEKLRLEEEALYAAQREAARAAKQRKLLEQERQ 131
            QE+K+R ++E +   + E  R  ++ + LE+  Q
Sbjct: 410 RQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQ 444



 Score = 28.5 bits (62), Expect = 7.6
 Identities = 20/77 (25%), Positives = 44/77 (57%), Gaps = 7/77 (9%)

Query: 66  EEEIVDLRE---RHYDSIAEKQKDLDKKI---QKELALQEEKLRLEEEALYAAQREAARA 119
           +E+I +  E   R  + I E+++   +K+   +K++  Q+EK+R +EE ++  Q E  R 
Sbjct: 380 DEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMW-RQEEKIRE 438

Query: 120 AKQRKLLEQERQRIVQQ 136
            ++    ++E+ R V++
Sbjct: 439 LEEMMQDQEEKLREVEE 455


>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 37/140 (26%), Positives = 67/140 (47%), Gaps = 8/140 (5%)

Query: 37  RGEHLTIEFENLVESDEGESPGSSHRPLTEEEIVDLRERHYDSIAEKQKDLDKKIQKE-- 94
           R E +  + + + E DE            EE+I +L E   D   EK +++++K+Q+E  
Sbjct: 404 RQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQ-EEKLREVEEKMQEEEE 462

Query: 95  -LALQEEKLRLEEEALYAAQREAARAAKQRKLLEQERQRIVQQYHPSNNGEYQSSGPEDD 153
            +  QEEK++ +EE +   Q +  +  +Q KLL+QE ++I +Q       E +    E+ 
Sbjct: 463 KMQEQEEKIQRQEEKI---QEQEEKTWRQEKLLKQE-EKIWEQEEKMWRQEEKMWEQEEK 518

Query: 154 FESCLRNMKSQYEVFRSSRL 173
            +     M+ Q E  R   +
Sbjct: 519 MQEQEEKMQRQEEKMREQEV 538



 Score = 31.6 bits (70), Expect = 0.90
 Identities = 25/93 (26%), Positives = 46/93 (49%), Gaps = 7/93 (7%)

Query: 46  ENLVESDEGESPGSSHRPLTEEEIVDLRERHYDSI---AEKQKDLDKKI---QKELALQE 99
           E + E DE            EE+I +  E+  + +    +K ++ D+KI   ++E+  QE
Sbjct: 374 EKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQE 433

Query: 100 EKLRLEEEALYAAQREAARAAKQRKLLEQERQR 132
           EK+R E E +   Q E  R  +++   E+E+ +
Sbjct: 434 EKIR-ELEEMMQDQEEKLREVEEKMQEEEEKMQ 465



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 23/100 (23%), Positives = 46/100 (46%), Gaps = 3/100 (3%)

Query: 37  RGEHLTIEFENLVESDEGESPGSSHRPLTEEEIVDLRERHYDSIAEKQKDLDKKIQKELA 96
           R E    E E  +   E +      +   +EE +  +E       EK ++ D+KIQ++  
Sbjct: 329 RQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQ-- 386

Query: 97  LQEEKLRLEEEALYAAQREAARAAKQRKLLEQERQRIVQQ 136
            +EE  R EE+     ++   +  +Q K + ++ ++I +Q
Sbjct: 387 -EEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQ 425



 Score = 30.0 bits (66), Expect = 2.6
 Identities = 21/95 (22%), Positives = 45/95 (47%)

Query: 37  RGEHLTIEFENLVESDEGESPGSSHRPLTEEEIVDLRERHYDSIAEKQKDLDKKIQKELA 96
           R E    E E  +   E +      +   ++E +  +E       EK ++ ++K Q+++ 
Sbjct: 350 RQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMW 409

Query: 97  LQEEKLRLEEEALYAAQREAARAAKQRKLLEQERQ 131
            QE+K+R ++E +   + E  R  ++ + LE+  Q
Sbjct: 410 RQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQ 444



 Score = 28.5 bits (62), Expect = 7.6
 Identities = 20/77 (25%), Positives = 44/77 (57%), Gaps = 7/77 (9%)

Query: 66  EEEIVDLRE---RHYDSIAEKQKDLDKKI---QKELALQEEKLRLEEEALYAAQREAARA 119
           +E+I +  E   R  + I E+++   +K+   +K++  Q+EK+R +EE ++  Q E  R 
Sbjct: 380 DEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMW-RQEEKIRE 438

Query: 120 AKQRKLLEQERQRIVQQ 136
            ++    ++E+ R V++
Sbjct: 439 LEEMMQDQEEKLREVEE 455


>gi|161702986 ezrin [Homo sapiens]
          Length = 586

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 27/73 (36%), Positives = 44/73 (60%), Gaps = 4/73 (5%)

Query: 64  LTEEEIVDLRERHYDSIAEK-QKDLDKKIQKELALQEEKLRLEEEALYAAQREAARAAKQ 122
           + E+E + LR + Y+   +K +++L ++IQ+ L L+EE+ R +EE   A + EA R A  
Sbjct: 341 MREKEELMLRLQDYEEKTKKAERELSEQIQRALQLEEERKRAQEE---AERLEADRMAAL 397

Query: 123 RKLLEQERQRIVQ 135
           R   E ERQ + Q
Sbjct: 398 RAKEELERQAVDQ 410



 Score = 30.0 bits (66), Expect = 2.6
 Identities = 19/87 (21%), Positives = 42/87 (48%), Gaps = 1/87 (1%)

Query: 74  ERHYDSIAEKQKDLDKKIQKELALQEEK-LRLEEEALYAAQREAARAAKQRKLLEQERQR 132
           E+H   +  +Q + +KK ++ +  ++E+ +R +EE +   Q    +  K  + L ++ QR
Sbjct: 312 EKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQR 371

Query: 133 IVQQYHPSNNGEYQSSGPEDDFESCLR 159
            +Q        + ++   E D  + LR
Sbjct: 372 ALQLEEERKRAQEEAERLEADRMAALR 398


>gi|21614499 ezrin [Homo sapiens]
          Length = 586

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 27/73 (36%), Positives = 44/73 (60%), Gaps = 4/73 (5%)

Query: 64  LTEEEIVDLRERHYDSIAEK-QKDLDKKIQKELALQEEKLRLEEEALYAAQREAARAAKQ 122
           + E+E + LR + Y+   +K +++L ++IQ+ L L+EE+ R +EE   A + EA R A  
Sbjct: 341 MREKEELMLRLQDYEEKTKKAERELSEQIQRALQLEEERKRAQEE---AERLEADRMAAL 397

Query: 123 RKLLEQERQRIVQ 135
           R   E ERQ + Q
Sbjct: 398 RAKEELERQAVDQ 410



 Score = 30.0 bits (66), Expect = 2.6
 Identities = 19/87 (21%), Positives = 42/87 (48%), Gaps = 1/87 (1%)

Query: 74  ERHYDSIAEKQKDLDKKIQKELALQEEK-LRLEEEALYAAQREAARAAKQRKLLEQERQR 132
           E+H   +  +Q + +KK ++ +  ++E+ +R +EE +   Q    +  K  + L ++ QR
Sbjct: 312 EKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQR 371

Query: 133 IVQQYHPSNNGEYQSSGPEDDFESCLR 159
            +Q        + ++   E D  + LR
Sbjct: 372 ALQLEEERKRAQEEAERLEADRMAALR 398


>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           9 [Homo sapiens]
          Length = 771

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 50/253 (19%), Positives = 96/253 (37%), Gaps = 41/253 (16%)

Query: 52  DEGESPGSSHRPLTEEEIVDLRERHYDSIAEKQKDLDKKIQKELALQ------------- 98
           DE        R   +E   + R+RH +   + +++ +++ ++E+A +             
Sbjct: 102 DEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLE 161

Query: 99  -----EEKLRLEEEALYAAQREAARAAKQRKLLEQERQRIVQQYHPSNNGEYQSS----- 148
                E K+R E++     Q+E  R A++R+  E+E +R V  +H +   +Y        
Sbjct: 162 RKRERERKMR-EQQKEQREQKERERRAEERR-KEREARREVSAHHRTMREDYSDKVKASH 219

Query: 149 -------GPEDDFESCLRNMKSQYEVFRSSRLSSDATVLTPNTESSCDLMTKTKSTSGND 201
                   P + FE        + E      L SD   ++ +   +    + +  +    
Sbjct: 220 WSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGS 279

Query: 202 DSTSLDLEWEDEEGMNRMLPMRERSKTEEDILRAALKYSNKKTGSNPTSASDDSNGLEWE 261
           +    + E E+EEG        E  + EE+          ++TGSN   AS+ S     E
Sbjct: 280 EEEEEEEEEEEEEGSTSEESEEEEEEEEEE---------EEETGSNSEEASEQSAEEVSE 330

Query: 262 NDFVSAEMDDNGN 274
            +    E  +N N
Sbjct: 331 EEMSEDEERENEN 343


>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           4 [Homo sapiens]
          Length = 737

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 50/253 (19%), Positives = 96/253 (37%), Gaps = 41/253 (16%)

Query: 52  DEGESPGSSHRPLTEEEIVDLRERHYDSIAEKQKDLDKKIQKELALQ------------- 98
           DE        R   +E   + R+RH +   + +++ +++ ++E+A +             
Sbjct: 68  DEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLE 127

Query: 99  -----EEKLRLEEEALYAAQREAARAAKQRKLLEQERQRIVQQYHPSNNGEYQSS----- 148
                E K+R E++     Q+E  R A++R+  E+E +R V  +H +   +Y        
Sbjct: 128 RKRERERKMR-EQQKEQREQKERERRAEERR-KEREARREVSAHHRTMREDYSDKVKASH 185

Query: 149 -------GPEDDFESCLRNMKSQYEVFRSSRLSSDATVLTPNTESSCDLMTKTKSTSGND 201
                   P + FE        + E      L SD   ++ +   +    + +  +    
Sbjct: 186 WSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGS 245

Query: 202 DSTSLDLEWEDEEGMNRMLPMRERSKTEEDILRAALKYSNKKTGSNPTSASDDSNGLEWE 261
           +    + E E+EEG        E  + EE+          ++TGSN   AS+ S     E
Sbjct: 246 EEEEEEEEEEEEEGSTSEESEEEEEEEEEE---------EEETGSNSEEASEQSAEEVSE 296

Query: 262 NDFVSAEMDDNGN 274
            +    E  +N N
Sbjct: 297 EEMSEDEERENEN 309


>gi|13027602 DDRGK domain containing 1 [Homo sapiens]
          Length = 314

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 41/167 (24%), Positives = 70/167 (41%), Gaps = 12/167 (7%)

Query: 48  LVESDEG-ESPGSSH----------RPLTEEEIVDLRERHYDSIAEKQKDLDKKIQKELA 96
           L + +EG E P  +H          R L E++    +    ++  E++K L+ + + E  
Sbjct: 98  LAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWK 157

Query: 97  LQEEKLRLEEEALYAAQREAARAAKQRKLLEQERQRIVQQYHPSNNGEYQSSGPEDDFES 156
            +EE+LRLEEE     +R+A     QR+  E  + +          GE  +      F +
Sbjct: 158 KEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLT 217

Query: 157 CLRNMKSQYEVFRSSRLSSDATVLTPNTESSC-DLMTKTKSTSGNDD 202
              N   Q +V     L+S   + T +T +   DL+ +   T   DD
Sbjct: 218 EFINYIKQSKVVLLEDLASQVGLRTQDTINRIQDLLAEGTITGVIDD 264


>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
          Length = 2003

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 46/214 (21%), Positives = 88/214 (41%), Gaps = 20/214 (9%)

Query: 33   RTCSRGEHLTIEFENLVESDEGESPGSSHRPLTEEEIVDLRERHYDSIAEKQKDLDKKIQ 92
            R  +R + L +    L E+  GE    S +  TE++ +    +  ++  E ++   +K+Q
Sbjct: 937  RLAARKQELELVVSEL-EARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQ 995

Query: 93   KELALQEEKLRLEEEALYAAQREAARAAKQRKLLEQERQRIVQQYHPSNNGEYQSSGPED 152
             E    E K++  EE L   + + ++ +K+RKLLE        Q           +  E+
Sbjct: 996  LEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQ-----------AAEEE 1044

Query: 153  DFESCLRNMKSQYEVFRSSRLSSDATVLTPNTESSCDLMTKTKSTSGNDDSTSLDLEWED 212
            +    L  ++ +YE        +D        E     + K K      D  S +L+ + 
Sbjct: 1045 EKVKSLNKLRLKYEA-----TIADMEDRLRKEEKGRQELEKLKRRL---DGESSELQEQM 1096

Query: 213  EEGMNRMLPMRERSKTEEDILRAALKYSNKKTGS 246
             E   R   +R +   +E+ L+AAL  +  + G+
Sbjct: 1097 VEQQQRAEELRAQLGRKEEELQAALARAEDEGGA 1130



 Score = 28.9 bits (63), Expect = 5.8
 Identities = 20/72 (27%), Positives = 40/72 (55%), Gaps = 3/72 (4%)

Query: 66   EEEIVDLRERHYDSIAEKQKDLDKKIQKELALQEEKLRLEEE-ALYAAQREAARAAKQRK 124
            E  + +LR+RH  ++ E  + L++  + + A ++ +L LE E +   A+  + + A+Q  
Sbjct: 1216 EAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEG 1275

Query: 125  LLEQERQRIVQQ 136
              EQ R+R+  Q
Sbjct: 1276 --EQRRRRLELQ 1285


>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
          Length = 1995

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 46/214 (21%), Positives = 88/214 (41%), Gaps = 20/214 (9%)

Query: 33   RTCSRGEHLTIEFENLVESDEGESPGSSHRPLTEEEIVDLRERHYDSIAEKQKDLDKKIQ 92
            R  +R + L +    L E+  GE    S +  TE++ +    +  ++  E ++   +K+Q
Sbjct: 929  RLAARKQELELVVSEL-EARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQ 987

Query: 93   KELALQEEKLRLEEEALYAAQREAARAAKQRKLLEQERQRIVQQYHPSNNGEYQSSGPED 152
             E    E K++  EE L   + + ++ +K+RKLLE        Q           +  E+
Sbjct: 988  LEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQ-----------AAEEE 1036

Query: 153  DFESCLRNMKSQYEVFRSSRLSSDATVLTPNTESSCDLMTKTKSTSGNDDSTSLDLEWED 212
            +    L  ++ +YE        +D        E     + K K      D  S +L+ + 
Sbjct: 1037 EKVKSLNKLRLKYEA-----TIADMEDRLRKEEKGRQELEKLKRRL---DGESSELQEQM 1088

Query: 213  EEGMNRMLPMRERSKTEEDILRAALKYSNKKTGS 246
             E   R   +R +   +E+ L+AAL  +  + G+
Sbjct: 1089 VEQQQRAEELRAQLGRKEEELQAALARAEDEGGA 1122



 Score = 28.9 bits (63), Expect = 5.8
 Identities = 20/72 (27%), Positives = 40/72 (55%), Gaps = 3/72 (4%)

Query: 66   EEEIVDLRERHYDSIAEKQKDLDKKIQKELALQEEKLRLEEE-ALYAAQREAARAAKQRK 124
            E  + +LR+RH  ++ E  + L++  + + A ++ +L LE E +   A+  + + A+Q  
Sbjct: 1208 EAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEG 1267

Query: 125  LLEQERQRIVQQ 136
              EQ R+R+  Q
Sbjct: 1268 --EQRRRRLELQ 1277


>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
          Length = 2036

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 46/214 (21%), Positives = 88/214 (41%), Gaps = 20/214 (9%)

Query: 33   RTCSRGEHLTIEFENLVESDEGESPGSSHRPLTEEEIVDLRERHYDSIAEKQKDLDKKIQ 92
            R  +R + L +    L E+  GE    S +  TE++ +    +  ++  E ++   +K+Q
Sbjct: 970  RLAARKQELELVVSEL-EARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQ 1028

Query: 93   KELALQEEKLRLEEEALYAAQREAARAAKQRKLLEQERQRIVQQYHPSNNGEYQSSGPED 152
             E    E K++  EE L   + + ++ +K+RKLLE        Q           +  E+
Sbjct: 1029 LEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQ-----------AAEEE 1077

Query: 153  DFESCLRNMKSQYEVFRSSRLSSDATVLTPNTESSCDLMTKTKSTSGNDDSTSLDLEWED 212
            +    L  ++ +YE        +D        E     + K K      D  S +L+ + 
Sbjct: 1078 EKVKSLNKLRLKYEA-----TIADMEDRLRKEEKGRQELEKLKRRL---DGESSELQEQM 1129

Query: 213  EEGMNRMLPMRERSKTEEDILRAALKYSNKKTGS 246
             E   R   +R +   +E+ L+AAL  +  + G+
Sbjct: 1130 VEQQQRAEELRAQLGRKEEELQAALARAEDEGGA 1163



 Score = 28.9 bits (63), Expect = 5.8
 Identities = 20/72 (27%), Positives = 40/72 (55%), Gaps = 3/72 (4%)

Query: 66   EEEIVDLRERHYDSIAEKQKDLDKKIQKELALQEEKLRLEEE-ALYAAQREAARAAKQRK 124
            E  + +LR+RH  ++ E  + L++  + + A ++ +L LE E +   A+  + + A+Q  
Sbjct: 1249 EAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEG 1308

Query: 125  LLEQERQRIVQQ 136
              EQ R+R+  Q
Sbjct: 1309 --EQRRRRLELQ 1318


>gi|120953300 leucine-rich repeats and IQ motif containing 1 isoform
           1 [Homo sapiens]
          Length = 1722

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 48/216 (22%), Positives = 86/216 (39%), Gaps = 31/216 (14%)

Query: 37  RGEHLTIEFENLVESDEGESPGSSHRPLTEEEIVDLRERH--------YDSIAEKQKDLD 88
           R  HL +E E     D+ E   +S         V ++ ++        Y  I ++Q +  
Sbjct: 255 RNLHLQMEEERTRFKDQQEKEKNSLLKQQNNAAVKIQAKYKAFVAYQKYGPIIKEQIESK 314

Query: 89  KKIQKELALQEEKLRLEEEALYAAQREAARAAKQR-KLLEQERQRIVQQYHPSNNGEYQS 147
           K+  +E   +E K+R +EE       E  R  ++R K  E+ER+R  ++Y    N   Q 
Sbjct: 315 KRKAQEWKEKEAKIRQKEEENRKRLEEEQRIKEERKKQKEEERKRREKEYEEKKNIVKQE 374

Query: 148 SGPEDDFESCLRNMKSQYEVFRSSRLSSDATVLTPNTESSCDLMTKTKSTSGNDDSTSLD 207
                                R   +S +  +L  +      + +  K +  N+   SL+
Sbjct: 375 ---------------------REQLISKEKIILREDASQQLIISSALKKSGYNNKHLSLE 413

Query: 208 LEWEDEEGMNRMLPMRERSKTEEDILRAALKYSNKK 243
               D+  + + L + E SK +ED+L   ++ SN K
Sbjct: 414 DISNDKGDIAKNL-VDENSKKQEDVLLWLVEESNMK 448



 Score = 29.3 bits (64), Expect = 4.5
 Identities = 35/184 (19%), Positives = 74/184 (40%), Gaps = 23/184 (12%)

Query: 68  EIVDLRERHYDSIAEKQKDLDKKIQKELALQEEKLRLEEEALYAAQREAARAAKQRKLLE 127
           E+ +   + +++  EKQK+L+ K ++ L  Q ++   EE+     + +     KQ K+ +
Sbjct: 162 EVEEKCRQSFEAWQEKQKELEDKEKQTLKAQRDR---EEKQFQEEEEKRHCWMKQFKVEK 218

Query: 128 QERQRIVQQYHPSNNGEYQSSGP--EDDF---ESCLRNMKSQYEV----FRSSRLSSDAT 178
           ++ + I +Q     N E        ++ F   E  +RN+  Q E     F+  +     +
Sbjct: 219 KKLENIQKQEQDKMNDELYKEEKIWKEKFKQHEEYIRNLHLQMEEERTRFKDQQEKEKNS 278

Query: 179 VLTPNTESSCDLMTKTKS-----------TSGNDDSTSLDLEWEDEEGMNRMLPMRERSK 227
           +L     ++  +  K K+               +       EW+++E   R      R +
Sbjct: 279 LLKQQNNAAVKIQAKYKAFVAYQKYGPIIKEQIESKKRKAQEWKEKEAKIRQKEEENRKR 338

Query: 228 TEED 231
            EE+
Sbjct: 339 LEEE 342


>gi|45439327 periplakin [Homo sapiens]
          Length = 1756

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 51/255 (20%), Positives = 94/255 (36%), Gaps = 10/255 (3%)

Query: 55   ESPGSSHRPLTEEEIVDLRERHYDSIAEKQKDLDKKIQKELALQEEKLRLEEEALYAAQR 114
            E PG         E +D+  R  D +  + + L ++ + EL  Q E+L  E +A   A+R
Sbjct: 1360 EEPGLRAEASAFAESIDVELRQIDKLRAELRRLQRR-RTELERQLEELERERQARREAER 1418

Query: 115  EAARAAKQRKLLEQERQRIVQQYHPSNNGEYQSSGPEDDFESCLRNMKSQYEVFRSSRLS 174
            E  R  ++   LEQE     ++   +     Q   P+   E  L  ++ + E  R   L 
Sbjct: 1419 EVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQD-PQQAREHALLRLQLEEEQHRRQLLE 1477

Query: 175  SDATVLTPNTESSCDLMTKTKSTSGNDDSTSLDLEWEDEEGMNRMLPMRERSKTEEDI-- 232
             +   L     +      K K               ++ + +   L    RSK E D+  
Sbjct: 1478 GELETLRRKLAALEKAEVKEKVVLSESVQVEKGDTEQEIQRLKSSLEEESRSKRELDVEV 1537

Query: 233  -----LRAALKYSNKKTGSNPTSASDDSNGLEWENDFVSAEMDDNGNSEYSGFVNPVLEL 287
                   + L++ N K+        ++++ L+ E   +  E      SE +       +L
Sbjct: 1538 SRLEARLSELEFHNSKSSKELDFLREENHKLQLERQNLQLE-TRRLQSEINMAATETRDL 1596

Query: 288  SDSGIRHSDTDQQTR 302
             +  +  S T+  +R
Sbjct: 1597 RNMTVADSGTNHDSR 1611



 Score = 29.3 bits (64), Expect = 4.5
 Identities = 43/159 (27%), Positives = 65/159 (40%), Gaps = 35/159 (22%)

Query: 13   LRKEAGRLQRVGGGGGSKYFRTCSRGEHLTIEFENLVES-DEGESPGSSHRPLTEEEIVD 71
            LR+E   L+R  G   ++      R   L  E     E   E E     + P  E E   
Sbjct: 1013 LREELEALRRQKGAREAEVLLLQQRVAALAEEKSRAQEKVTEKEVVKLQNDPQLEAEYQQ 1072

Query: 72   LRERHY--DSIAEKQK-------DLDKKIQKELALQEEKLRLEE----EALYAAQREA-- 116
            L+E H   D + EKQ+       D  K+++KE A+ E K+ ++E    E   A +RE   
Sbjct: 1073 LQEDHQRQDQLREKQEEELSFLQDKLKRLEKERAMAEGKITVKEVLKVEKDAATEREVSD 1132

Query: 117  -----------ARAAKQRKL--------LEQERQRIVQQ 136
                       ARA+++ K         LE+E  ++V Q
Sbjct: 1133 LTRQYEDEAAKARASQREKTELLRKIWALEEENAKVVVQ 1171


>gi|120953243 leucine-rich repeats and IQ motif containing 1 isoform
           2 [Homo sapiens]
          Length = 1336

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 48/216 (22%), Positives = 86/216 (39%), Gaps = 31/216 (14%)

Query: 37  RGEHLTIEFENLVESDEGESPGSSHRPLTEEEIVDLRERH--------YDSIAEKQKDLD 88
           R  HL +E E     D+ E   +S         V ++ ++        Y  I ++Q +  
Sbjct: 255 RNLHLQMEEERTRFKDQQEKEKNSLLKQQNNAAVKIQAKYKAFVAYQKYGPIIKEQIESK 314

Query: 89  KKIQKELALQEEKLRLEEEALYAAQREAARAAKQR-KLLEQERQRIVQQYHPSNNGEYQS 147
           K+  +E   +E K+R +EE       E  R  ++R K  E+ER+R  ++Y    N   Q 
Sbjct: 315 KRKAQEWKEKEAKIRQKEEENRKRLEEEQRIKEERKKQKEEERKRREKEYEEKKNIVKQE 374

Query: 148 SGPEDDFESCLRNMKSQYEVFRSSRLSSDATVLTPNTESSCDLMTKTKSTSGNDDSTSLD 207
                                R   +S +  +L  +      + +  K +  N+   SL+
Sbjct: 375 ---------------------REQLISKEKIILREDASQQLIISSALKKSGYNNKHLSLE 413

Query: 208 LEWEDEEGMNRMLPMRERSKTEEDILRAALKYSNKK 243
               D+  + + L + E SK +ED+L   ++ SN K
Sbjct: 414 DISNDKGDIAKNL-VDENSKKQEDVLLWLVEESNMK 448



 Score = 29.3 bits (64), Expect = 4.5
 Identities = 35/184 (19%), Positives = 74/184 (40%), Gaps = 23/184 (12%)

Query: 68  EIVDLRERHYDSIAEKQKDLDKKIQKELALQEEKLRLEEEALYAAQREAARAAKQRKLLE 127
           E+ +   + +++  EKQK+L+ K ++ L  Q ++   EE+     + +     KQ K+ +
Sbjct: 162 EVEEKCRQSFEAWQEKQKELEDKEKQTLKAQRDR---EEKQFQEEEEKRHCWMKQFKVEK 218

Query: 128 QERQRIVQQYHPSNNGEYQSSGP--EDDF---ESCLRNMKSQYEV----FRSSRLSSDAT 178
           ++ + I +Q     N E        ++ F   E  +RN+  Q E     F+  +     +
Sbjct: 219 KKLENIQKQEQDKMNDELYKEEKIWKEKFKQHEEYIRNLHLQMEEERTRFKDQQEKEKNS 278

Query: 179 VLTPNTESSCDLMTKTKS-----------TSGNDDSTSLDLEWEDEEGMNRMLPMRERSK 227
           +L     ++  +  K K+               +       EW+++E   R      R +
Sbjct: 279 LLKQQNNAAVKIQAKYKAFVAYQKYGPIIKEQIESKKRKAQEWKEKEAKIRQKEEENRKR 338

Query: 228 TEED 231
            EE+
Sbjct: 339 LEEE 342


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 38.9 bits (89), Expect = 0.006
 Identities = 44/158 (27%), Positives = 71/158 (44%), Gaps = 18/158 (11%)

Query: 12   LLRKEAGRLQRVGGGGGSKYFRTCSRGEHLTIEFENLV-ESDEGESPGSSHRPLTEEEIV 70
            LLR+E  + +R       +  R C   E L  E E L+ E  E        R   EEE V
Sbjct: 1093 LLREEPEKRRR------QERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEV 1146

Query: 71   DLRERHYDSIAEKQKDLDKKIQKELALQ---EEKLRLEEEALYAAQREAARAAKQRKLLE 127
               E         +++ +K+ ++EL  Q   EE+L+ EEE L   ++E  R  ++R+  E
Sbjct: 1147 QQEEEQL-----LREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYRE 1201

Query: 128  QE---RQRIVQQYHPSNNGEYQSSGPEDDFESCLRNMK 162
            +E   RQ+  Q+Y   +         E + E+ +R+ K
Sbjct: 1202 EEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNK 1239



 Score = 35.0 bits (79), Expect = 0.081
 Identities = 25/90 (27%), Positives = 46/90 (51%), Gaps = 5/90 (5%)

Query: 62  RPLTEEEIVDLRERHYDSIAEKQKDLDKKIQKELALQEEKLRLEEEALYAAQREAARAAK 121
           R   EEE  + R+R  +++  K+++   K+Q+E   ++ +L+ EEE L   +R+  R  +
Sbjct: 236 RVFQEEEEKEWRKR--ETVLRKEEE---KLQEEEPQRQRELQEEEEQLRKLERQELRRER 290

Query: 122 QRKLLEQERQRIVQQYHPSNNGEYQSSGPE 151
           Q +  +Q+R R  QQ       E +    E
Sbjct: 291 QEEEQQQQRLRREQQLRRKQEEERREQQEE 320



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 23/75 (30%), Positives = 42/75 (56%), Gaps = 5/75 (6%)

Query: 66   EEEIVDLRERHYDSIAEKQKDLDKKIQKELALQEEKLRLEEEALYAAQREAARAAKQRKL 125
            EEE + L E+  +    +++D   + +++ A QE K R EE+ L+  + +  R  ++RKL
Sbjct: 1824 EEEQLQLEEQ--EQRLRQERDRQYRAEEQFATQE-KSRREEQELWQEEEQKRRQERERKL 1880

Query: 126  LEQ--ERQRIVQQYH 138
             E+   RQ+  +Q H
Sbjct: 1881 REEHIRRQQKEEQRH 1895



 Score = 33.5 bits (75), Expect = 0.24
 Identities = 43/181 (23%), Positives = 76/181 (41%), Gaps = 33/181 (18%)

Query: 62   RPLTEEEIVDLRERHYDSIAEKQ-------KDLDKKIQKELALQEEKLRLEEEALYAAQR 114
            R  TE+E +  +ER+   + E+Q       + L ++ +     +EE+LR E E      +
Sbjct: 1732 RQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQ 1791

Query: 115  EAARAAKQRKLLEQERQRIVQQYHP-SNNGEYQSSGPEDDFESCLRNMKSQYEVFRSSRL 173
            E+ R  ++ + L QER+   QQ  P   +G+Y+       +E     ++ Q +  R  R 
Sbjct: 1792 ESDRKFREEEQLRQEREE--QQLRPQQRDGKYR-------WEEEQLQLEEQEQRLRQER- 1841

Query: 174  SSDATVLTPNTESSCDLMTKTKSTSGNDDSTSLDLEWEDEEGMNRMLPMRERSKTEEDIL 233
                     + +   +    T+  S  ++       W++EE   R    RER   EE I 
Sbjct: 1842 ---------DRQYRAEEQFATQEKSRREEQEL----WQEEEQKRRQ--ERERKLREEHIR 1886

Query: 234  R 234
            R
Sbjct: 1887 R 1887



 Score = 32.0 bits (71), Expect = 0.69
 Identities = 36/132 (27%), Positives = 54/132 (40%), Gaps = 15/132 (11%)

Query: 6   WTQCFGLLRKEAGRLQRVGGGGGSKYFRTCSRGEHLTIEFENLVESDEGESPGSSHRPLT 65
           W +   +LRKE  +LQ               R   L  E E L + +  E      R   
Sbjct: 246 WRKRETVLRKEEEKLQE----------EEPQRQRELQEEEEQLRKLERQEL----RRERQ 291

Query: 66  EEEIVDLRERHYDSIAEKQKDLDKKIQKELALQEEKLRLEEEAL-YAAQREAARAAKQRK 124
           EEE    R R    +  KQ++  ++ Q+E   Q+E+   +EE      +RE     +Q+ 
Sbjct: 292 EEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQL 351

Query: 125 LLEQERQRIVQQ 136
             EQE +R  QQ
Sbjct: 352 RREQEEERREQQ 363



 Score = 31.6 bits (70), Expect = 0.90
 Identities = 44/220 (20%), Positives = 90/220 (40%), Gaps = 8/220 (3%)

Query: 12  LLRKEAGRLQRVGGGGGSKYFRTCSRGEHLTIEFENLVESDEGESPGSSHRPLTEEEIVD 71
           L R+E  RL++       K  +   R + L  E E   +  + E      + L  EE+  
Sbjct: 550 LKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVER 609

Query: 72  LRERHYDSIAEKQKDLDKKIQKELALQEEKLRLEEEALYAAQREAARAAKQRKLLEQERQ 131
           L +        K+++ +++ +++L   EE+   EE      +RE     +QR   E+E +
Sbjct: 610 LEQEERREQRLKREEPEEERRQQLLKSEEQ---EERRQQQLRREQQERREQRLKREEEEE 666

Query: 132 RIVQQYHPSNNGEYQSSG-PEDDFESCLRNMKSQYEVFRSSRLSSDATVLTPNTESSCDL 190
           R+ Q+    +  E +     E++ E     +KS+   ++  +L S+A        S    
Sbjct: 667 RLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQ-WQLESEADARQSKVYSRPRK 725

Query: 191 MTKTKSTSGNDDS---TSLDLEWEDEEGMNRMLPMRERSK 227
               +     ++       +L+W++EE  +R     E+ +
Sbjct: 726 QEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRR 765



 Score = 31.6 bits (70), Expect = 0.90
 Identities = 31/141 (21%), Positives = 61/141 (43%), Gaps = 18/141 (12%)

Query: 44   EFENLVESDEGESPGSSHRPLTEEEIVDLRERHYDSIAEKQKDLD--------KKIQKEL 95
            E E     +E +     HR   EEE + L+ER    +  +++D          ++ +++ 
Sbjct: 1443 ERERKFLEEEQQLRQERHRKFREEEQL-LQEREEQQLHRQERDRKFLEEEQQLRRQERDR 1501

Query: 96   ALQEEKLRLEE--EALYAAQREAARAAKQRKLLEQERQRIVQQYHPSNNGEYQSSGPEDD 153
              +E++LR +E        +++  R  +QRK L++E     QQ      G+ +    +  
Sbjct: 1502 KFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEE-----QQLRRQERGQQRRQDRDRK 1556

Query: 154  F--ESCLRNMKSQYEVFRSSR 172
            F  E  LR  + + ++ R  R
Sbjct: 1557 FREEEQLRQEREEQQLSRQER 1577



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 20/88 (22%), Positives = 45/88 (51%), Gaps = 3/88 (3%)

Query: 49  VESDEGESPGSSHRPLTEEEIVDLRERHYDSIAEKQKDLDKKIQKELALQEEKLRLEEEA 108
           ++ D+ E        L EEE  + +ER    +  +Q++   + ++ L  QEE+ RL++  
Sbjct: 476 LKRDQEEERRERWLKLEEEERREQQERREQQLRREQEE---RREQRLKRQEEEERLQQRL 532

Query: 109 LYAAQREAARAAKQRKLLEQERQRIVQQ 136
               Q    +  ++ +LL++E ++ ++Q
Sbjct: 533 RSEQQLRREQEERREQLLKREEEKRLEQ 560



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 18/90 (20%), Positives = 42/90 (46%)

Query: 64  LTEEEIVDLRERHYDSIAEKQKDLDKKIQKELALQEEKLRLEEEALYAAQREAARAAKQR 123
           L +EE  +L+    +    ++++   + +++L  +EE+L  EE      Q    +  K +
Sbjct: 905 LLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDK 964

Query: 124 KLLEQERQRIVQQYHPSNNGEYQSSGPEDD 153
           KL ++E Q + ++       E +    E++
Sbjct: 965 KLQQKEEQLLGEEPEKRRRQEREKKYREEE 994



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 25/92 (27%), Positives = 47/92 (51%), Gaps = 12/92 (13%)

Query: 66   EEEIVDLRERHYDSIAEKQK---DLDKKIQKELALQEEKLRLEEEALYAAQREAARAAKQ 122
            EE+ V  +ER    + E+Q+   +  +K ++E  L +E+   EE+ L+  +R+     ++
Sbjct: 1435 EEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQER---EEQQLHRQERDRKFLEEE 1491

Query: 123  RKLLEQERQRIVQQYHPSNNGEYQSSGPEDDF 154
            ++L  QER R  ++       E +S  PE  F
Sbjct: 1492 QQLRRQERDRKFREQ------ELRSQEPERKF 1517



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 20/67 (29%), Positives = 39/67 (58%), Gaps = 6/67 (8%)

Query: 66   EEEIVDLRERHYDSIAEKQKDLDKKIQKELALQEEKLRLEEEALYAAQREAARAAKQRKL 125
            EE+ +  +ER    + E+Q+   ++++++   +EE+LR E E     Q +  R  + RK+
Sbjct: 1696 EEQQLRRQERERKFLQEEQQLRRQELERKFR-EEEQLRQETE-----QEQLRRQERYRKI 1749

Query: 126  LEQERQR 132
            LE+E+ R
Sbjct: 1750 LEEEQLR 1756



 Score = 30.0 bits (66), Expect = 2.6
 Identities = 32/173 (18%), Positives = 67/173 (38%), Gaps = 7/173 (4%)

Query: 62   RPLTEEEIVDLRERHYDSIAEKQKDLDKKIQKELALQEEKLRLEEEALYAAQREAARAAK 121
            +P  +E++     +    + E++++L ++ +++   QE++ +  EE     + E     +
Sbjct: 892  KPALQEQL----RKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREE 947

Query: 122  QRKLLEQERQRIVQQYHPSNNGEYQSSGPEDDFESCLRNMKSQYEVFRSSRLSSDATVLT 181
            + K   QER+R  ++       E Q  G E +     R  + + +      L  +   L 
Sbjct: 948  REKRRRQERERQYRKDKKLQQKEEQLLGEEPEKR---RRQEREKKYREEEELQQEEEQLL 1004

Query: 182  PNTESSCDLMTKTKSTSGNDDSTSLDLEWEDEEGMNRMLPMRERSKTEEDILR 234
                         +     D+    + +   EE   R L  RER   EE+ L+
Sbjct: 1005 REEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQ 1057



 Score = 29.6 bits (65), Expect = 3.4
 Identities = 26/89 (29%), Positives = 47/89 (52%), Gaps = 4/89 (4%)

Query: 50   ESDEGESPGSSHRPLTEEEIVDLRERHYDSIAEKQKDLDKKIQKELALQEE--KLRLEEE 107
            E +E      + R   EEE + L+ER    +  +++D  K  ++EL  QE+  K   EE+
Sbjct: 1324 EREEKRRRQETDRKFREEEQL-LQEREEQPLRRQERDR-KFREEELRHQEQGRKFLEEEQ 1381

Query: 108  ALYAAQREAARAAKQRKLLEQERQRIVQQ 136
             L   +RE     ++++L  QER++ ++Q
Sbjct: 1382 RLRRQERERKFLKEEQQLRCQEREQQLRQ 1410



 Score = 29.3 bits (64), Expect = 4.5
 Identities = 28/131 (21%), Positives = 62/131 (47%), Gaps = 13/131 (9%)

Query: 12   LLRKEAGRLQRVGGGGGSKYFRTCSRGEHLTIEFENLVESDEGESPGSSHRPLTEEEIVD 71
            LLR+E  + +R       ++ R   + + L  E E L+  +E E      R     E  +
Sbjct: 1003 LLREEREKRRR------QEWERQYRKKDELQQEEEQLLR-EEREKRRLQERERQYREEEE 1055

Query: 72   LRERHYDSIAEKQKDLDKKIQKELALQEEKLRLEEEALYAAQ------REAARAAKQRKL 125
            L++     + E+++   ++  +    +EE+L+ EEE L   +      +E  R  ++ + 
Sbjct: 1056 LQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEE 1115

Query: 126  LEQERQRIVQQ 136
            L+QE ++++++
Sbjct: 1116 LQQEEEQLLRE 1126



 Score = 28.9 bits (63), Expect = 5.8
 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 11/79 (13%)

Query: 62  RPLTEEEIVDLRERHYDSIAEKQKDLD--------KKIQKELALQEEKLRLEEEALYAAQ 113
           R L EEE  + R R      E++K+L         ++ ++   LQEE+  L+E+      
Sbjct: 809 RFLPEEEEKEQRRRQR---REREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRS 865

Query: 114 REAARAAKQRKLLEQERQR 132
           +E  R  K R  LE+ER+R
Sbjct: 866 QEQRRDQKWRWQLEEERKR 884



 Score = 28.1 bits (61), Expect = 10.0
 Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 9/81 (11%)

Query: 54   GESPGSSHRPLTEEEIVDLRERHYDSIAEKQKDLDKKIQKELALQ---EEKLRLEEEALY 110
            GE P    R   E++  +  E   +     +++ +K+ ++E   Q   +++L+ EEE L 
Sbjct: 975  GEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLL 1034

Query: 111  AAQREAARAAKQRKLLEQERQ 131
              +RE      +R+L E+ERQ
Sbjct: 1035 REERE------KRRLQERERQ 1049



 Score = 28.1 bits (61), Expect = 10.0
 Identities = 26/99 (26%), Positives = 46/99 (46%), Gaps = 5/99 (5%)

Query: 39   EHLTIEFENLV-ESDEGESPGSSHRPLTEEEIVDLRERHYDSIAEKQKDLDKKIQKELAL 97
            E L  E E L+ E  E        R   +EE  +L++     + E+ +   ++ ++    
Sbjct: 1054 EELQQEEEQLLGEERETRRRQELERQYRKEE--ELQQEEEQLLREEPEKRRRQERERQCR 1111

Query: 98   QEEKLRLEEEALYAAQREAARAAKQRKLLEQERQRIVQQ 136
            +EE+L+ EEE L   +RE  R  +  +   +E +  VQQ
Sbjct: 1112 EEEELQQEEEQLLREEREKRRRQELERQYREEEE--VQQ 1148



 Score = 28.1 bits (61), Expect = 10.0
 Identities = 18/70 (25%), Positives = 40/70 (57%), Gaps = 1/70 (1%)

Query: 64   LTEEEIVDLRERHYDSIAEKQKDLDKKIQKELAL-QEEKLRLEEEALYAAQREAARAAKQ 122
            L EE+ +  +ER    + E+Q+   ++ +++L   ++ K R EE+ L   +R+     ++
Sbjct: 1377 LEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEE 1436

Query: 123  RKLLEQERQR 132
            +++  QER+R
Sbjct: 1437 QQVRRQERER 1446



 Score = 28.1 bits (61), Expect = 10.0
 Identities = 15/67 (22%), Positives = 36/67 (53%)

Query: 66   EEEIVDLRERHYDSIAEKQKDLDKKIQKELALQEEKLRLEEEALYAAQREAARAAKQRKL 125
            EE+ +  +ER      E+Q+   ++ +++   +E++LR E    +  + +  +  ++++L
Sbjct: 1419 EEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQL 1478

Query: 126  LEQERQR 132
              QER R
Sbjct: 1479 HRQERDR 1485



 Score = 28.1 bits (61), Expect = 10.0
 Identities = 25/92 (27%), Positives = 43/92 (46%), Gaps = 3/92 (3%)

Query: 44   EFENLVESDEGESPGSSHRPLTEEEIVDLRERHYD-SIAEKQKDLDKKIQKELALQEEK- 101
            E E  +  D         + L E E   LR +  D    E+++ L ++ ++   LQEE+ 
Sbjct: 1656 EREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQ 1715

Query: 102  LRLEE-EALYAAQREAARAAKQRKLLEQERQR 132
            LR +E E  +  + +  +  +Q +L  QER R
Sbjct: 1716 LRRQELERKFREEEQLRQETEQEQLRRQERYR 1747


>gi|4758648 kinesin family member 5B [Homo sapiens]
          Length = 963

 Score = 38.5 bits (88), Expect = 0.007
 Identities = 44/196 (22%), Positives = 89/196 (45%), Gaps = 25/196 (12%)

Query: 60  SHRPLTEEEIVDLRERHYDSIAEKQKDLDKKIQKELALQEEKLRLEEEALYAAQREAARA 119
           SHR   +++I  LR+   ++ A+   DL  + QK + L++E+LR+E E L A  +E +R 
Sbjct: 707 SHRETHQKQISSLRDE-VEAKAKLITDLQDQNQK-MMLEQERLRVEHEKLKATDQEKSRK 764

Query: 120 AKQRKLLEQERQRIVQQYHPSNNGEYQSSGPEDDFESCLRNMKSQYEVFRSSRLSSDATV 179
             +  +++  R++  Q       G  ++   E      L N++  +    ++R+   A +
Sbjct: 765 LHELTVMQDRREQARQDL----KGLEETVAKE---LQTLHNLRKLFVQDLATRVKKSAEI 817

Query: 180 LTPNT-------------ESSCDLMTKTKSTSGNDDSTSLDLEWEDEEGMNRMLPMRERS 226
            + +T             E++ + +TK       D++   DL  E  +   R+    ER 
Sbjct: 818 DSDDTGGSAAQKQKISFLENNLEQLTKVHKQLVRDNA---DLRCELPKLEKRLRATAERV 874

Query: 227 KTEEDILRAALKYSNK 242
           K  E  L+ A + +++
Sbjct: 875 KALESALKEAKENASR 890


>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 436

 Score = 38.1 bits (87), Expect = 0.010
 Identities = 33/156 (21%), Positives = 71/156 (45%), Gaps = 9/156 (5%)

Query: 11  GLLRKEAGRLQRVGGGGGSKYFRTCSRGEHLTIEFENLVESDEGESPGSSHRPLTEEEIV 70
           G +R++ G+++   G  G +  +   + E +  + E + + +E            EE++ 
Sbjct: 178 GQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMG 237

Query: 71  DLRERHYDSIAEKQKDLDKKIQKELALQEEKLRLEEEALYAAQREAARAAKQRKLLEQER 130
           +  E+      +KQ++  +K ++++  QEE++R +EE +   + +  +  KQ++  EQE 
Sbjct: 238 EQEEQ-----VQKQEEQVQKQEEQMRKQEEQMREQEEQM---REQEEQMLKQKEQTEQEE 289

Query: 131 QRIVQQYHPSNNGEYQSSGPEDDFESCLRNMKSQYE 166
           Q   +Q       E Q    E+        M+ Q E
Sbjct: 290 Q-TGEQEEQMREQEEQMREQEEQMREQEEQMREQEE 324



 Score = 28.9 bits (63), Expect = 5.8
 Identities = 19/105 (18%), Positives = 54/105 (51%), Gaps = 4/105 (3%)

Query: 66  EEEIVDLRER-HYDSIAEKQKDLDKKIQKELALQEEKLRLEEEALYAAQREAARAAKQRK 124
           EE+++  +E+   +    +Q++  ++ ++++  QEE++R +EE +   + +  +  KQ +
Sbjct: 275 EEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQM---REQEEQMGKQEE 331

Query: 125 LLEQERQRIVQQYHPSNNGEYQSSGPEDDFESCLRNMKSQYEVFR 169
            + ++++++ +Q       E Q    E+  +     ++ Q E  R
Sbjct: 332 QMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMR 376



 Score = 28.5 bits (62), Expect = 7.6
 Identities = 11/55 (20%), Positives = 38/55 (69%), Gaps = 3/55 (5%)

Query: 82  EKQKDLDKKIQKELALQEEKLRLEEEALYAAQREAARAAKQRKLLEQERQRIVQQ 136
           +KQ++  +K ++++  QEE++R +EE +   +++  +  +Q++ + ++++++ +Q
Sbjct: 362 QKQEEQVRKQEEQMRKQEEQMRKQEEQM---RKQEEQMGEQKEQMGEQKEQMREQ 413



 Score = 28.1 bits (61), Expect = 10.0
 Identities = 18/98 (18%), Positives = 49/98 (50%), Gaps = 5/98 (5%)

Query: 39  EHLTIEFENLVESDEGESPGSSHRPLTEEEIVDLRERHYDSIAEKQKDLDKKIQKELALQ 98
           E +  + E + E +E            EE++ + +E+ ++     QK+   K ++++  Q
Sbjct: 303 EQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWE-----QKEQMWKQEEQMGEQ 357

Query: 99  EEKLRLEEEALYAAQREAARAAKQRKLLEQERQRIVQQ 136
           EE+++ +EE +   + +  +  +Q +  E++ ++  +Q
Sbjct: 358 EEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQ 395



 Score = 28.1 bits (61), Expect = 10.0
 Identities = 16/69 (23%), Positives = 36/69 (52%), Gaps = 2/69 (2%)

Query: 83  KQKDLDKKIQKELALQEEKLRLEEEALYAAQREAARAAKQRKLLEQERQRIVQQYHPSNN 142
           KQ++  +K ++++  QEE++R +EE +   +++     ++ ++ EQE Q   Q+      
Sbjct: 370 KQEEQMRKQEEQMRKQEEQMRKQEEQM--GEQKEQMGEQKEQMREQEEQMGEQKEQMRKQ 427

Query: 143 GEYQSSGPE 151
            E+     E
Sbjct: 428 EEHMGEQKE 436


>gi|64276486 serologically defined colon cancer antigen 10 [Homo
           sapiens]
          Length = 472

 Score = 38.1 bits (87), Expect = 0.010
 Identities = 48/210 (22%), Positives = 90/210 (42%), Gaps = 47/210 (22%)

Query: 48  LVESDEGESPG----SSHRPLTEEEIVDLRERHY--DSIAEKQK-------------DLD 88
           +VES++G++P             +E +D  E++   + IA+K K             +++
Sbjct: 247 VVESEKGDAPDLVDDGEDESAEHDEYIDGDEKNLMRERIAKKLKKDTSANVKSAGEGEVE 306

Query: 89  KK-IQKELALQEEKLRLEEEALYAAQREAARAAKQRKLLEQERQRIVQQYHPSNNGEYQS 147
           KK + +   L++E  +L+ E L A Q++   AAKQ +   +E +                
Sbjct: 307 KKSVSRSEELRKEARQLKRELLAAKQKKVENAAKQAEKRSEEEE---------------- 350

Query: 148 SGPEDDFESCLRNMKSQYEVFRSSRLSSDATVLTPNTESSCDLMT--KTKSTSGNDDSTS 205
             P D   +  R  K +YE  R  +        T   + +  L+   K+K T    ++  
Sbjct: 351 -APPDGAVAEYRREKQKYEALRKQQSKKG----TSREDQTLALLNQFKSKLTQAIAETPE 405

Query: 206 LDL---EWEDEEG-MNRMLPMRERSKTEED 231
            D+   E ED+EG M+ +L   ++S+  +D
Sbjct: 406 NDIPETEVEDDEGWMSHVLQFEDKSRKVKD 435


>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
          Length = 237

 Score = 38.1 bits (87), Expect = 0.010
 Identities = 37/194 (19%), Positives = 87/194 (44%), Gaps = 13/194 (6%)

Query: 62  RPLTEE--EIVDLRERHYDSIAEKQKDLDKKIQKELALQEEKLRLEEEALYAAQREAARA 119
           RP  EE  E ++ +++   ++AE ++ +++  +KEL    EKL    E+          +
Sbjct: 28  RPTWEEVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSES----------S 77

Query: 120 AKQRKLLEQERQRIVQQYHPSNNGEYQSSGPEDDFESCLRNMKSQYEVFRSSRLSSDATV 179
           +K+R+  ++E+++  +    S++    SS   D  +   +  K + +    S  SS++++
Sbjct: 78  SKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSM 137

Query: 180 LTPNTESSCDLMTKTKSTSGNDDSTSLDLEWEDEEGMNRMLPMRERSKTEEDILRAALKY 239
               ++S   L  K KS  G +    +    +  +  +   P+   S +E + +   ++ 
Sbjct: 138 SETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIE-EVRA 196

Query: 240 SNKKTGSNPTSASD 253
             KK+      A++
Sbjct: 197 KKKKSSEEREKATE 210


>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
          Length = 247

 Score = 38.1 bits (87), Expect = 0.010
 Identities = 37/194 (19%), Positives = 87/194 (44%), Gaps = 13/194 (6%)

Query: 62  RPLTEE--EIVDLRERHYDSIAEKQKDLDKKIQKELALQEEKLRLEEEALYAAQREAARA 119
           RP  EE  E ++ +++   ++AE ++ +++  +KEL    EKL    E+          +
Sbjct: 38  RPTWEEVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSES----------S 87

Query: 120 AKQRKLLEQERQRIVQQYHPSNNGEYQSSGPEDDFESCLRNMKSQYEVFRSSRLSSDATV 179
           +K+R+  ++E+++  +    S++    SS   D  +   +  K + +    S  SS++++
Sbjct: 88  SKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSM 147

Query: 180 LTPNTESSCDLMTKTKSTSGNDDSTSLDLEWEDEEGMNRMLPMRERSKTEEDILRAALKY 239
               ++S   L  K KS  G +    +    +  +  +   P+   S +E + +   ++ 
Sbjct: 148 SETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIE-EVRA 206

Query: 240 SNKKTGSNPTSASD 253
             KK+      A++
Sbjct: 207 KKKKSSEEREKATE 220


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 37.7 bits (86), Expect = 0.013
 Identities = 40/186 (21%), Positives = 79/186 (42%), Gaps = 18/186 (9%)

Query: 67  EEIVDLRERHYDSIAEKQ-KDLDKKIQKELALQEEKLRLEEEALYAAQREAARAAKQRKL 125
           E++  +RE       EK+ +D ++K+Q+E  ++E + ++ EE     ++E     ++  +
Sbjct: 421 EQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENM 480

Query: 126 LEQERQRIVQQYHPSNNGEY--QSSGPED-----DFESCLRNMKSQY----EVFRSSRLS 174
            EQE +   QQ  P    +   Q    E      + E  +R+ +  +    +++R  ++ 
Sbjct: 481 WEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMR 540

Query: 175 SDATVLTPNTESSCDLMTKTKSTSGNDDSTSLDLE---WEDEEGMNRMLPMRERSK---T 228
                +    E   D   K        +  + + E   W+ EE M     MRER K    
Sbjct: 541 EQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 600

Query: 229 EEDILR 234
           EE+++R
Sbjct: 601 EEEMMR 606



 Score = 35.4 bits (80), Expect = 0.062
 Identities = 34/121 (28%), Positives = 60/121 (49%), Gaps = 16/121 (13%)

Query: 53  EGESPGSSHRPLTEEEIVDLRERHYDSIAEKQKDLDKKIQK---ELALQEEKLRLEEEAL 109
           E ES     + + EEE + +RE+      EK ++ ++K+Q+   E+  QEEK+  +EE +
Sbjct: 711 EEESMREREKKMREEEEM-MREQE-----EKMQEQEEKMQEQEEEMWEQEEKMWEQEEKM 764

Query: 110 YAAQREAARAAKQRKLLE----QERQRIVQQYHPSNNGEYQSSGPEDDFESCLRNMKSQY 165
           +  QR      ++ KL E    QE+++I +Q     + E +  G E+        M+ Q 
Sbjct: 765 WEQQR---LPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQE 821

Query: 166 E 166
           E
Sbjct: 822 E 822



 Score = 31.6 bits (70), Expect = 0.90
 Identities = 25/131 (19%), Positives = 53/131 (40%), Gaps = 2/131 (1%)

Query: 39  EHLTIEFENLVESDEGESPGSSHRPLTEEEIVDLRERHYDSIAEKQKDLDKKIQKELALQ 98
           E +  E E  ++  E +      +   +EE +  +E       EK  + ++K+ ++  L 
Sbjct: 602 EEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLP 661

Query: 99  EEKLRLEEEALYAAQREAARAAKQRKLLEQERQRIVQQYHPSNNGEYQSSGPEDDFESCL 158
           E+K +L E      Q +     ++ K+ EQE+     Q       + +    E+      
Sbjct: 662 EQKEKLWEHE--KMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRERE 719

Query: 159 RNMKSQYEVFR 169
           + M+ + E+ R
Sbjct: 720 KKMREEEEMMR 730



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 26/96 (27%), Positives = 51/96 (53%), Gaps = 10/96 (10%)

Query: 46  ENLVESDEGESPGSSHRPLTEEEIVDLRERHYDSIAEKQKDLDKKIQKELALQEEKLRLE 105
           E  +   EG+      +   +E+   LRE+  + + E++K+L +  QKEL  QEE+++ +
Sbjct: 299 EERLREQEGKMREQEEKMWRQEK--RLREQEKE-LREQEKELRE--QKELREQEEQMQEQ 353

Query: 106 EEALYAAQ-----REAARAAKQRKLLEQERQRIVQQ 136
           EE ++  +     +E     ++ +L EQE+Q   Q+
Sbjct: 354 EEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE 389



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 22/81 (27%), Positives = 42/81 (51%), Gaps = 9/81 (11%)

Query: 64  LTEEEIVDLRERHYDSIAEKQKDLDKKIQKELALQEEKLRLEEEALYAAQ-----REAAR 118
           + EEE +  RE+      E  ++ ++K+Q+    QEEK++ +EE ++  +     +E   
Sbjct: 585 MREEERMREREKKMREEEEMMREQEEKMQE----QEEKMQEQEEKMWEQEEKMQEQEEKM 640

Query: 119 AAKQRKLLEQERQRIVQQYHP 139
             ++ K+ EQE +   QQ  P
Sbjct: 641 WEQEEKMWEQEEKMWEQQRLP 661



 Score = 29.6 bits (65), Expect = 3.4
 Identities = 40/189 (21%), Positives = 77/189 (40%), Gaps = 28/189 (14%)

Query: 66  EEEIVDLRERHYDS---IAEKQKDLDKKI--QKELALQEEKLRLEEEALYAAQREAARAA 120
           EE++ D  ++ +D    + +K ++ +KK   Q+E   +EE++R  E+ +   + E     
Sbjct: 550 EEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKM--REEEEMMRE 607

Query: 121 KQRKLLEQERQRIVQQYHPSNNGEYQSSGPEDDFESCLRNMKSQYEVFRSSRL------- 173
           ++ K+ EQE +   Q+       E      E  +E   +  + + +++   RL       
Sbjct: 608 QEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKL 667

Query: 174 -----SSDATVLTPNTESSCDLMTKTKSTSGNDDSTSLDLEWEDEEGMNRMLPMRERSK- 227
                  +   +    E   +     K T   +  T     W D+E M     MRER K 
Sbjct: 668 WEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKT-----W-DQEKMREEESMREREKK 721

Query: 228 --TEEDILR 234
              EE+++R
Sbjct: 722 MREEEEMMR 730



 Score = 29.3 bits (64), Expect = 4.5
 Identities = 22/89 (24%), Positives = 51/89 (57%), Gaps = 8/89 (8%)

Query: 52  DEGESPGSSHRPLTEEEIVDLRERHYDSIAEKQ-KDLDKKIQKE---LALQEEKLRLEEE 107
           ++ E      + L E+E  +LRE+  +   +K+ ++ ++++Q++   +  QEEK+R +EE
Sbjct: 311 EQEEKMWRQEKRLREQE-KELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEE 369

Query: 108 ALYAAQREAARAAKQRKLLEQERQRIVQQ 136
            ++   R+  R  +Q K + ++ Q++  Q
Sbjct: 370 KMW---RQEERLWEQEKQMREQEQKMRDQ 395



 Score = 28.9 bits (63), Expect = 5.8
 Identities = 33/169 (19%), Positives = 66/169 (39%), Gaps = 15/169 (8%)

Query: 75  RHYDSIAEKQKDLDKKIQK------ELALQEEKLRLEEEALYAAQREAARAAKQRKLLEQ 128
           R  + + E++K + K+ +K       L  QE K+R +EE ++   R+  R  +Q K L +
Sbjct: 276 RQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMW---RQEKRLREQEKELRE 332

Query: 129 ERQRIVQQYHPSNNGEYQSSGPEDDFESCLRNMKSQYEVFR-SSRLSSDATVLTPNTESS 187
           + + + +Q       E      E  +E   +  + + +++R   RL      +    +  
Sbjct: 333 QEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKM 392

Query: 188 CDLMTK-----TKSTSGNDDSTSLDLEWEDEEGMNRMLPMRERSKTEED 231
            D   +      +     +     +  WE  E M     M+E+ K   D
Sbjct: 393 RDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRD 441



 Score = 28.9 bits (63), Expect = 5.8
 Identities = 20/85 (23%), Positives = 42/85 (49%), Gaps = 1/85 (1%)

Query: 46  ENLVESDEGESPGSSHRPLTEEEIVDLRERHYDSIAEKQKDLDKKIQKELALQEEKLRLE 105
           E  +   E +  G   +   +EE +  +E       EK    ++K+++++  QEEK+R +
Sbjct: 807 EEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQ 866

Query: 106 EEALYAAQREAARAAKQRKLLEQER 130
           EE +   Q E  R  +++   ++E+
Sbjct: 867 EEKM-RGQEEKMREQEEKMRGQEEK 890



 Score = 28.5 bits (62), Expect = 7.6
 Identities = 22/101 (21%), Positives = 47/101 (46%), Gaps = 5/101 (4%)

Query: 66  EEEIVDLRERHYDSIAEKQKDLDKKIQKELALQEEKLRLEEEALYAAQREAARAAKQRKL 125
           E+++ +  E+  D   +K  D +++++K+   QE+K   +EE +    RE  R  ++ K 
Sbjct: 543 EDQMWEQEEKMRDQ-EQKMWDQEERMEKKTQEQEKKTWDQEEKM----REEERMREREKK 597

Query: 126 LEQERQRIVQQYHPSNNGEYQSSGPEDDFESCLRNMKSQYE 166
           + +E + + +Q       E +    E+        M+ Q E
Sbjct: 598 MREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEE 638


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.126    0.354 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,827,206
Number of Sequences: 37866
Number of extensions: 562655
Number of successful extensions: 5106
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 157
Number of HSP's successfully gapped in prelim test: 390
Number of HSP's that attempted gapping in prelim test: 3165
Number of HSP's gapped (non-prelim): 1734
length of query: 302
length of database: 18,247,518
effective HSP length: 102
effective length of query: 200
effective length of database: 14,385,186
effective search space: 2877037200
effective search space used: 2877037200
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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