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Search of human proteins with 190014603
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|190014603 TBC1 domain family, member 13 [Homo sapiens]
(400 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|190014603 TBC1 domain family, member 13 [Homo sapiens] 815 0.0
gi|197304777 TBC1 domain family, member 5 isoform a [Homo sapiens] 113 3e-25
gi|197304775 TBC1 domain family, member 5 isoform b [Homo sapiens] 113 3e-25
gi|7661998 TBC1 domain family, member 5 isoform b [Homo sapiens] 113 3e-25
gi|40068063 TBC1 domain family, member 22B [Homo sapiens] 93 5e-19
gi|22507409 TBC1 domain family, member 22A [Homo sapiens] 92 6e-19
gi|226342869 TBC1 domain family, member 15 isoform 2 [Homo sapiens] 81 2e-15
gi|226342867 TBC1 domain family, member 15 isoform 3 [Homo sapiens] 81 2e-15
gi|226342865 TBC1 domain family, member 15 isoform 1 [Homo sapiens] 81 2e-15
gi|13375952 TBC1 domain family, member 17 [Homo sapiens] 74 2e-13
gi|33563376 TBC1 domain family, member 16 [Homo sapiens] 67 4e-11
gi|54607014 TBC1 domain family, member 25 [Homo sapiens] 60 5e-09
gi|34147456 TBC domain-containing protein kinase-like [Homo sapi... 58 1e-08
gi|148612875 RUN and TBC1 domain containing 2 isoform 4 [Homo sa... 54 2e-07
gi|148612840 RUN and TBC1 domain containing 2 isoform 3 [Homo sa... 54 2e-07
gi|90577164 RUN and TBC1 domain containing 2 isoform 2 [Homo sap... 54 2e-07
gi|90577167 RUN and TBC1 domain containing 2 isoform 1 [Homo sap... 54 2e-07
gi|148806902 TBC1 domain family, member 12 [Homo sapiens] 50 4e-06
gi|148612829 RUN and TBC1 domain containing 1 isoform 2 [Homo sa... 49 8e-06
gi|148612795 RUN and TBC1 domain containing 1 isoform 1 [Homo sa... 49 8e-06
gi|164565381 TBC1 domain family, member 14 isoform b [Homo sapiens] 49 1e-05
gi|164565368 TBC1 domain family, member 14 isoform a [Homo sapiens] 49 1e-05
gi|164565366 TBC1 domain family, member 14 isoform a [Homo sapiens] 49 1e-05
gi|114688046 TBC1 domain family, member 4 [Homo sapiens] 45 2e-04
gi|68299759 ecotropic viral integration site 5 [Homo sapiens] 40 0.005
gi|222352143 TBC1 domain family, member 2 [Homo sapiens] 39 0.006
gi|50658061 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member... 39 0.008
gi|118722351 growth hormone regulated TBC protein 1 [Homo sapiens] 39 0.011
gi|229577000 ecotropic viral integration site 5-like isoform 1 [... 38 0.014
gi|21687020 ecotropic viral integration site 5-like isoform 2 [H... 38 0.014
>gi|190014603 TBC1 domain family, member 13 [Homo sapiens]
Length = 400
Score = 815 bits (2105), Expect = 0.0
Identities = 400/400 (100%), Positives = 400/400 (100%)
Query: 1 MSSLHKSRIADFQDVLKEPSIALEKLRELSFSGIPCEGGLRCLCWKILLNYLPLERASWT 60
MSSLHKSRIADFQDVLKEPSIALEKLRELSFSGIPCEGGLRCLCWKILLNYLPLERASWT
Sbjct: 1 MSSLHKSRIADFQDVLKEPSIALEKLRELSFSGIPCEGGLRCLCWKILLNYLPLERASWT 60
Query: 61 SILAKQRELYAQFLREMIIQPGIAKANMGVSREDVTFEDHPLNPNPDSRWNTYFKDNEVL 120
SILAKQRELYAQFLREMIIQPGIAKANMGVSREDVTFEDHPLNPNPDSRWNTYFKDNEVL
Sbjct: 61 SILAKQRELYAQFLREMIIQPGIAKANMGVSREDVTFEDHPLNPNPDSRWNTYFKDNEVL 120
Query: 121 LQIDKDVRRLCPDISFFQRATDYPCLLILDPQNEFETLRKRVEQTTLKSQTVARNRSGVT 180
LQIDKDVRRLCPDISFFQRATDYPCLLILDPQNEFETLRKRVEQTTLKSQTVARNRSGVT
Sbjct: 121 LQIDKDVRRLCPDISFFQRATDYPCLLILDPQNEFETLRKRVEQTTLKSQTVARNRSGVT 180
Query: 181 NMSSPHKNSVPSSLNEYEVLPNGCEAHWEVVERILFIYAKLNPGIAYVQGMNEIVGPLYY 240
NMSSPHKNSVPSSLNEYEVLPNGCEAHWEVVERILFIYAKLNPGIAYVQGMNEIVGPLYY
Sbjct: 181 NMSSPHKNSVPSSLNEYEVLPNGCEAHWEVVERILFIYAKLNPGIAYVQGMNEIVGPLYY 240
Query: 241 TFATDPNSEWKEHAEADTFFCFTNLMAEIRDNFIKSLDDSQCGITYKMEKVYSTLKDKDV 300
TFATDPNSEWKEHAEADTFFCFTNLMAEIRDNFIKSLDDSQCGITYKMEKVYSTLKDKDV
Sbjct: 241 TFATDPNSEWKEHAEADTFFCFTNLMAEIRDNFIKSLDDSQCGITYKMEKVYSTLKDKDV 300
Query: 301 ELYLKLQEQNIKPQFFAFRWLTLLLSQEFLLPDVIRIWDSLFADDNRFDFLLLVCCAMLM 360
ELYLKLQEQNIKPQFFAFRWLTLLLSQEFLLPDVIRIWDSLFADDNRFDFLLLVCCAMLM
Sbjct: 301 ELYLKLQEQNIKPQFFAFRWLTLLLSQEFLLPDVIRIWDSLFADDNRFDFLLLVCCAMLM 360
Query: 361 LIREQLLEGDFTVNMRLLQDYPITDVCQILQKAKELQDSK 400
LIREQLLEGDFTVNMRLLQDYPITDVCQILQKAKELQDSK
Sbjct: 361 LIREQLLEGDFTVNMRLLQDYPITDVCQILQKAKELQDSK 400
>gi|197304777 TBC1 domain family, member 5 isoform a [Homo sapiens]
Length = 817
Score = 113 bits (282), Expect = 3e-25
Identities = 101/386 (26%), Positives = 168/386 (43%), Gaps = 47/386 (12%)
Query: 23 LEKLRELSFSGIPCEGGLRCLCWKILLNYLPLERASWTSILAKQRELYAQFLREMIIQPG 82
L +R+ +G R +CWK+ L LP +++ W S + + R Y+ I P
Sbjct: 69 LATIRQKGINGQLRSSRFRSICWKLFLCVLPQDKSQWISRIEELRAWYSNIKEIHITNP- 127
Query: 83 IAKANMGVSREDVTFEDHPLNPNPDSRWNTYFKDNEVLLQIDKDVRRLCPDISFFQRATD 142
V ++D+ ++PL+ + S WN +F+D E+ I++DV+R P++ FFQ+
Sbjct: 128 ----RKVVGQQDLMI-NNPLSQDEGSLWNKFFQDKELRSMIEQDVKRTFPEMQFFQQ--- 179
Query: 143 YPCLLILDPQNEFETLRKRVEQTTLKSQTVARNRSGVTNMSSPHKNSVPSSL---NEYEV 199
E +RK + AR + H+ P +++
Sbjct: 180 -------------ENVRKILTDVLF---CYARENEQLLYKQGMHELLAPIVFVLHCDHQA 223
Query: 200 LPNGCEAHW--EVVERILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNSEWKEHAEAD 257
+ E+ E ++ +L + A + E P + TF D + KE
Sbjct: 224 FLHASESAQPSEEMKTVLNPEYLEHDAYAVFSQLMETAEPWFSTFEHD-GQKGKE----- 277
Query: 258 TFFCFTNLMAEIRDNFIKSLD-DSQCGITYKMEKVYSTL-KDKDVELYLKLQEQNIKPQF 315
LM I F + D I K+ ++ L K D+ELY+ L I PQ
Sbjct: 278 ------TLMTPI--PFARPQDLGPTIAIVTKVNQIQDHLLKKHDIELYMHLNRLEIAPQI 329
Query: 316 FAFRWLTLLLSQEFLLPDVIRIWDSLFADDNRFDFLLLVCCAMLMLIREQLLEGDFTVNM 375
+ RW+ LL +EF L D++ +WD+LFAD + + AML+ IR+ L+ ++ +
Sbjct: 330 YGLRWVRLLFGREFPLQDLLVVWDALFADGLSLGLVDYIFVAMLLYIRDALISSNYQTCL 389
Query: 376 RLLQDYP-ITDVCQILQKAKELQDSK 400
LL YP I DV ++ KA L+D K
Sbjct: 390 GLLMHYPFIGDVHSLILKALFLRDPK 415
>gi|197304775 TBC1 domain family, member 5 isoform b [Homo sapiens]
Length = 795
Score = 113 bits (282), Expect = 3e-25
Identities = 101/386 (26%), Positives = 168/386 (43%), Gaps = 47/386 (12%)
Query: 23 LEKLRELSFSGIPCEGGLRCLCWKILLNYLPLERASWTSILAKQRELYAQFLREMIIQPG 82
L +R+ +G R +CWK+ L LP +++ W S + + R Y+ I P
Sbjct: 69 LATIRQKGINGQLRSSRFRSICWKLFLCVLPQDKSQWISRIEELRAWYSNIKEIHITNP- 127
Query: 83 IAKANMGVSREDVTFEDHPLNPNPDSRWNTYFKDNEVLLQIDKDVRRLCPDISFFQRATD 142
V ++D+ ++PL+ + S WN +F+D E+ I++DV+R P++ FFQ+
Sbjct: 128 ----RKVVGQQDLMI-NNPLSQDEGSLWNKFFQDKELRSMIEQDVKRTFPEMQFFQQ--- 179
Query: 143 YPCLLILDPQNEFETLRKRVEQTTLKSQTVARNRSGVTNMSSPHKNSVPSSL---NEYEV 199
E +RK + AR + H+ P +++
Sbjct: 180 -------------ENVRKILTDVLF---CYARENEQLLYKQGMHELLAPIVFVLHCDHQA 223
Query: 200 LPNGCEAHW--EVVERILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNSEWKEHAEAD 257
+ E+ E ++ +L + A + E P + TF D + KE
Sbjct: 224 FLHASESAQPSEEMKTVLNPEYLEHDAYAVFSQLMETAEPWFSTFEHD-GQKGKE----- 277
Query: 258 TFFCFTNLMAEIRDNFIKSLD-DSQCGITYKMEKVYSTL-KDKDVELYLKLQEQNIKPQF 315
LM I F + D I K+ ++ L K D+ELY+ L I PQ
Sbjct: 278 ------TLMTPI--PFARPQDLGPTIAIVTKVNQIQDHLLKKHDIELYMHLNRLEIAPQI 329
Query: 316 FAFRWLTLLLSQEFLLPDVIRIWDSLFADDNRFDFLLLVCCAMLMLIREQLLEGDFTVNM 375
+ RW+ LL +EF L D++ +WD+LFAD + + AML+ IR+ L+ ++ +
Sbjct: 330 YGLRWVRLLFGREFPLQDLLVVWDALFADGLSLGLVDYIFVAMLLYIRDALISSNYQTCL 389
Query: 376 RLLQDYP-ITDVCQILQKAKELQDSK 400
LL YP I DV ++ KA L+D K
Sbjct: 390 GLLMHYPFIGDVHSLILKALFLRDPK 415
>gi|7661998 TBC1 domain family, member 5 isoform b [Homo sapiens]
Length = 795
Score = 113 bits (282), Expect = 3e-25
Identities = 101/386 (26%), Positives = 168/386 (43%), Gaps = 47/386 (12%)
Query: 23 LEKLRELSFSGIPCEGGLRCLCWKILLNYLPLERASWTSILAKQRELYAQFLREMIIQPG 82
L +R+ +G R +CWK+ L LP +++ W S + + R Y+ I P
Sbjct: 69 LATIRQKGINGQLRSSRFRSICWKLFLCVLPQDKSQWISRIEELRAWYSNIKEIHITNP- 127
Query: 83 IAKANMGVSREDVTFEDHPLNPNPDSRWNTYFKDNEVLLQIDKDVRRLCPDISFFQRATD 142
V ++D+ ++PL+ + S WN +F+D E+ I++DV+R P++ FFQ+
Sbjct: 128 ----RKVVGQQDLMI-NNPLSQDEGSLWNKFFQDKELRSMIEQDVKRTFPEMQFFQQ--- 179
Query: 143 YPCLLILDPQNEFETLRKRVEQTTLKSQTVARNRSGVTNMSSPHKNSVPSSL---NEYEV 199
E +RK + AR + H+ P +++
Sbjct: 180 -------------ENVRKILTDVLF---CYARENEQLLYKQGMHELLAPIVFVLHCDHQA 223
Query: 200 LPNGCEAHW--EVVERILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNSEWKEHAEAD 257
+ E+ E ++ +L + A + E P + TF D + KE
Sbjct: 224 FLHASESAQPSEEMKTVLNPEYLEHDAYAVFSQLMETAEPWFSTFEHD-GQKGKE----- 277
Query: 258 TFFCFTNLMAEIRDNFIKSLD-DSQCGITYKMEKVYSTL-KDKDVELYLKLQEQNIKPQF 315
LM I F + D I K+ ++ L K D+ELY+ L I PQ
Sbjct: 278 ------TLMTPI--PFARPQDLGPTIAIVTKVNQIQDHLLKKHDIELYMHLNRLEIAPQI 329
Query: 316 FAFRWLTLLLSQEFLLPDVIRIWDSLFADDNRFDFLLLVCCAMLMLIREQLLEGDFTVNM 375
+ RW+ LL +EF L D++ +WD+LFAD + + AML+ IR+ L+ ++ +
Sbjct: 330 YGLRWVRLLFGREFPLQDLLVVWDALFADGLSLGLVDYIFVAMLLYIRDALISSNYQTCL 389
Query: 376 RLLQDYP-ITDVCQILQKAKELQDSK 400
LL YP I DV ++ KA L+D K
Sbjct: 390 GLLMHYPFIGDVHSLILKALFLRDPK 415
>gi|40068063 TBC1 domain family, member 22B [Homo sapiens]
Length = 505
Score = 92.8 bits (229), Expect = 5e-19
Identities = 61/189 (32%), Positives = 100/189 (52%), Gaps = 19/189 (10%)
Query: 209 EVVERILFIYAKLNPGIAYVQGMNEIVGPLYYTF-------------ATDPNSEWKEHAE 255
E+ ERILFI+A +P YVQG+N++V P + F T+ + + E
Sbjct: 289 EIFERILFIWAIRHPASGYVQGINDLVTPFFVVFLSEYVEEDVENFDVTNLSQDMLRSIE 348
Query: 256 ADTFFCFTNLMAEIRDNFIKSLDDSQCGITYKMEKVYSTLKDKDVELYLKLQEQNIKPQF 315
AD+F+C + L+ I+DN+ + Q GI K++ + + D +++ + ++
Sbjct: 349 ADSFWCMSKLLDGIQDNYTFA----QPGIQKKVKALEELVSRIDEQVHNHFRRYEVEYLQ 404
Query: 316 FAFRWLTLLLSQEFLLPDVIRIWDSLFADDNRFD-FLLLVCCAMLMLIREQLL-EGDFTV 373
FAFRW+ LL +E L IR+WD+ ++ F F L VC A L+ R+++L E DF
Sbjct: 405 FAFRWMNNLLMRELPLRCTIRLWDTYQSEPEGFSHFHLYVCAAFLIKWRKEILDEEDFQG 464
Query: 374 NMRLLQDYP 382
+ LLQ+ P
Sbjct: 465 LLMLLQNLP 473
Score = 43.5 bits (101), Expect = 3e-04
Identities = 23/76 (30%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Query: 1 MSSLHKSRIADFQDVLKEPSIALEKLRELSFSGIPCEGGLRCLCWKILLNYLPLERASWT 60
M+ K+R+ F+ +L + L++LR+ S+ G+P E +R + W++L YLP
Sbjct: 178 MTVREKTRLEKFRQLLSSQNTDLDELRKCSWPGVPRE--VRPITWRLLSGYLPANTERRK 235
Query: 61 SILAKQRELYAQFLRE 76
L ++RE Y F+ +
Sbjct: 236 LTLQRKREEYFGFIEQ 251
>gi|22507409 TBC1 domain family, member 22A [Homo sapiens]
Length = 517
Score = 92.4 bits (228), Expect = 6e-19
Identities = 65/210 (30%), Positives = 109/210 (51%), Gaps = 25/210 (11%)
Query: 209 EVVERILFIYAKLNPGIAYVQGMNEIVGPLYYTFATD--------------PNSEWKEHA 254
E+ ERILFI+A +P YVQG+N++V P + F + +E +
Sbjct: 300 EIFERILFIWAIRHPASGYVQGINDLVTPFFVVFICEYIEAEEVDTVDVSGVPAEVLCNI 359
Query: 255 EADTFFCFTNLMAEIRDNFIKSLDDSQCGITYKMEKVYSTLKDKDVELYLKLQEQNIKPQ 314
EADT++C + L+ I+DN+ + Q GI K++ + + D +++ L + ++
Sbjct: 360 EADTYWCMSKLLDGIQDNYTFA----QPGIQMKVKMLEELVSRIDEQVHRHLDQHEVRYL 415
Query: 315 FFAFRWLTLLLSQEFLLPDVIRIWDSLFADDNRFD-FLLLVCCAMLMLIREQLL-EGDFT 372
FAFRW+ LL +E L IR+WD+ ++ + F F L VC A L+ R+++L E DF
Sbjct: 416 QFAFRWMNNLLMREVPLRCTIRLWDTYQSEPDGFSHFHLYVCAAFLVRWRKEILEEKDFQ 475
Query: 373 VNMRLLQDYPIT-----DVCQILQKAKELQ 397
+ LQ+ P D+ +L +A L+
Sbjct: 476 ELLLFLQNLPTAHWDDEDISLLLAEAYRLK 505
Score = 45.1 bits (105), Expect = 1e-04
Identities = 26/74 (35%), Positives = 42/74 (56%), Gaps = 2/74 (2%)
Query: 1 MSSLHKSRIADFQDVLKEPSIALEKLRELSFSGIPCEGGLRCLCWKILLNYLPLERASWT 60
+S SR+ F+ +L P+ LE+LR LS+SGIP +R + WK+L YLP
Sbjct: 190 LSEREASRLDKFKQLLAGPNTDLEELRRLSWSGIP--KPVRPMTWKLLSGYLPANVDRRP 247
Query: 61 SILAKQRELYAQFL 74
+ L ++++ Y F+
Sbjct: 248 ATLQRKQKEYFAFI 261
>gi|226342869 TBC1 domain family, member 15 isoform 2 [Homo sapiens]
Length = 682
Score = 80.9 bits (198), Expect = 2e-15
Identities = 51/186 (27%), Positives = 94/186 (50%), Gaps = 17/186 (9%)
Query: 214 ILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNSEWKEHAEADTFFCFTNLMAEIRDNF 273
IL Y + + YVQGM++++ PL Y E D F+CF + M ++ NF
Sbjct: 430 ILMTYCMYDFDLGYVQGMSDLLSPLLYVMEN----------EVDAFWCFASYMDQMHQNF 479
Query: 274 IKSLDDSQCGITYKMEKVYSTLKDKDVELYLKLQEQNIKPQFFAFRWLTLLLSQEFLLPD 333
++ G+ ++ ++ + L+ D L+ Q+ +F FRWL + +EF D
Sbjct: 480 ----EEQMQGMKTQLIQLSTLLRLLDSGFCSYLESQDSGYLYFCFRWLLIRFKREFSFLD 535
Query: 334 VIRIWDSLFADDNRFDFLLLVCCAMLMLIREQLLEGDFTVNMRLLQDYPIT---DVCQIL 390
++R+W+ ++ + +F LL+CCA+L ++Q++E + N L ++ DV IL
Sbjct: 536 ILRLWEVMWTELPCTNFHLLLCCAILESEKQQIMEKHYGFNEILKHINELSMKIDVEDIL 595
Query: 391 QKAKEL 396
KA+ +
Sbjct: 596 CKAEAI 601
>gi|226342867 TBC1 domain family, member 15 isoform 3 [Homo sapiens]
Length = 696
Score = 80.9 bits (198), Expect = 2e-15
Identities = 51/186 (27%), Positives = 94/186 (50%), Gaps = 17/186 (9%)
Query: 214 ILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNSEWKEHAEADTFFCFTNLMAEIRDNF 273
IL Y + + YVQGM++++ PL Y E D F+CF + M ++ NF
Sbjct: 444 ILMTYCMYDFDLGYVQGMSDLLSPLLYVMEN----------EVDAFWCFASYMDQMHQNF 493
Query: 274 IKSLDDSQCGITYKMEKVYSTLKDKDVELYLKLQEQNIKPQFFAFRWLTLLLSQEFLLPD 333
++ G+ ++ ++ + L+ D L+ Q+ +F FRWL + +EF D
Sbjct: 494 ----EEQMQGMKTQLIQLSTLLRLLDSGFCSYLESQDSGYLYFCFRWLLIRFKREFSFLD 549
Query: 334 VIRIWDSLFADDNRFDFLLLVCCAMLMLIREQLLEGDFTVNMRLLQDYPIT---DVCQIL 390
++R+W+ ++ + +F LL+CCA+L ++Q++E + N L ++ DV IL
Sbjct: 550 ILRLWEVMWTELPCTNFHLLLCCAILESEKQQIMEKHYGFNEILKHINELSMKIDVEDIL 609
Query: 391 QKAKEL 396
KA+ +
Sbjct: 610 CKAEAI 615
>gi|226342865 TBC1 domain family, member 15 isoform 1 [Homo sapiens]
Length = 713
Score = 80.9 bits (198), Expect = 2e-15
Identities = 51/186 (27%), Positives = 94/186 (50%), Gaps = 17/186 (9%)
Query: 214 ILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNSEWKEHAEADTFFCFTNLMAEIRDNF 273
IL Y + + YVQGM++++ PL Y E D F+CF + M ++ NF
Sbjct: 461 ILMTYCMYDFDLGYVQGMSDLLSPLLYVMEN----------EVDAFWCFASYMDQMHQNF 510
Query: 274 IKSLDDSQCGITYKMEKVYSTLKDKDVELYLKLQEQNIKPQFFAFRWLTLLLSQEFLLPD 333
++ G+ ++ ++ + L+ D L+ Q+ +F FRWL + +EF D
Sbjct: 511 ----EEQMQGMKTQLIQLSTLLRLLDSGFCSYLESQDSGYLYFCFRWLLIRFKREFSFLD 566
Query: 334 VIRIWDSLFADDNRFDFLLLVCCAMLMLIREQLLEGDFTVNMRLLQDYPIT---DVCQIL 390
++R+W+ ++ + +F LL+CCA+L ++Q++E + N L ++ DV IL
Sbjct: 567 ILRLWEVMWTELPCTNFHLLLCCAILESEKQQIMEKHYGFNEILKHINELSMKIDVEDIL 626
Query: 391 QKAKEL 396
KA+ +
Sbjct: 627 CKAEAI 632
>gi|13375952 TBC1 domain family, member 17 [Homo sapiens]
Length = 648
Score = 74.3 bits (181), Expect = 2e-13
Identities = 48/161 (29%), Positives = 78/161 (48%), Gaps = 14/161 (8%)
Query: 214 ILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNSEWKEHAEADTFFCFTNLMAEIRDNF 273
IL Y + + YVQGM++++ P+ Y E D F+CF M ++ NF
Sbjct: 403 ILLTYCMYHFDLGYVQGMSDLLSPILYVIQN----------EVDAFWCFCGFMELVQGNF 452
Query: 274 IKSLDDSQCGITYKMEKVYSTLKDKDVELYLKLQEQNIKPQFFAFRWLTLLLSQEFLLPD 333
++SQ + ++ ++ L+ D L L Q+ F FRWL + +EF PD
Sbjct: 453 ----EESQETMKRQLGRLLLLLRVLDPLLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPD 508
Query: 334 VIRIWDSLFADDNRFDFLLLVCCAMLMLIREQLLEGDFTVN 374
V+R+W+ L+ + LLV CA+L + R+ L+ F N
Sbjct: 509 VLRLWEVLWTGLPGPNLHLLVACAILDMERDTLMLSGFGSN 549
>gi|33563376 TBC1 domain family, member 16 [Homo sapiens]
Length = 767
Score = 66.6 bits (161), Expect = 4e-11
Identities = 51/177 (28%), Positives = 79/177 (44%), Gaps = 26/177 (14%)
Query: 209 EVVERILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNSEWKEHAEADTFFCFTNLMAE 268
E + RIL YA NP + Y QGM+++V P+ E+DTF+CF LM
Sbjct: 511 ESMRRILLNYAVYNPAVGYSQGMSDLVAPILAEVLD----------ESDTFWCFVGLMQN 560
Query: 269 IRDNFIKSLDDSQCGITYKMEKVYSTLKD----KDVELY---LKLQEQNIKPQFFAFRWL 321
F+ S D MEK L++ V Y + L E ++ F RWL
Sbjct: 561 TI--FVSSPRDED------MEKQLLYLRELLRLTHVRFYQHLVSLGEDGLQ-MLFCHRWL 611
Query: 322 TLLLSQEFLLPDVIRIWDSLFADDNRFDFLLLVCCAMLMLIREQLLEGDFTVNMRLL 378
L +EF + +RIW++ +A F L +C A++ + + ++E + LL
Sbjct: 612 LLCFKREFPEAEALRIWEACWAHYQTDYFHLFICVAIVAIYGDDVIEQQLATDQMLL 668
>gi|54607014 TBC1 domain family, member 25 [Homo sapiens]
Length = 688
Score = 59.7 bits (143), Expect = 5e-09
Identities = 42/142 (29%), Positives = 62/142 (43%), Gaps = 18/142 (12%)
Query: 207 HWEVVERILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNSEWKEHAEADTFFCFTNLM 266
H + +L YA +P ++Y QGM+++ P+ +H E F CF +M
Sbjct: 310 HLRALHDLLTTYAVTHPQVSYCQGMSDLASPILAVM---------DH-EGHAFVCFCGIM 359
Query: 267 AEIRDNFIKSLDDSQCGITYKMEKVYSTLKDKDVELYLKLQEQNIKPQFFAFRWLTLLLS 326
+ NF D + T K + L+ D + Y LQE FF +RWL L L
Sbjct: 360 KRLAANFHP---DGRAMAT-KFAHLKLLLRHADPDFYQYLQEAGADDLFFCYRWLLLELK 415
Query: 327 QEFLLPDVIRI----WDSLFAD 344
+EF D +R+ W SL D
Sbjct: 416 REFAFDDALRMLEVTWSSLPPD 437
>gi|34147456 TBC domain-containing protein kinase-like [Homo
sapiens]
Length = 830
Score = 58.2 bits (139), Expect = 1e-08
Identities = 49/203 (24%), Positives = 89/203 (43%), Gaps = 16/203 (7%)
Query: 195 NEYEVLPNGCEAHWEVVERILFIYAKLNPGIAYVQGMNEIVGP-LYYTFATDPNSEWKEH 253
++Y+ L + E H + R+L + +P + Y QG++ + P LY F +
Sbjct: 450 HQYDELLSSPEGHAKF-RRVLKAWVVSHPDLVYWQGLDSLCAPFLYLNF----------N 498
Query: 254 AEADTFFCFTNLMAEIRDNFIKSLDDSQCGITYKMEKVYSTLKDKDVELYLKLQEQNIKP 313
EA + C + + + NF L D+ I + + D EL L E P
Sbjct: 499 NEALAYACMSAFIPKYLYNFF--LKDNSHVIQEYLTVFSQMIAFHDPELSNHLNEIGFIP 556
Query: 314 QFFAFRWLTLLLSQEFLLPDVIRIWDSLFADDNRFDFLLLVCCAMLMLIREQLLEGDFTV 373
+A W + + F L + +WD+L ++ F F + V A+L +R++LL F
Sbjct: 557 DLYAIPWFLTMFTHVFPLHKIFHLWDTLLLGNSSFPFCIGV--AILQQLRDRLLANGFNE 614
Query: 374 NMRLLQDYPITDVCQILQKAKEL 396
+ L D P D+ + ++++ L
Sbjct: 615 CILLFSDLPEIDIERCVRESINL 637
>gi|148612875 RUN and TBC1 domain containing 2 isoform 4 [Homo
sapiens]
Length = 1032
Score = 53.9 bits (128), Expect = 2e-07
Identities = 49/197 (24%), Positives = 89/197 (45%), Gaps = 21/197 (10%)
Query: 206 AHWEVVERILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNSEWKEHAEADTFFCFTNL 265
A+ E + I+ Y + I YVQGM +++ PL EA F CFT L
Sbjct: 840 ANLEKLRNIMCSYIWQHIEIGYVQGMCDLLAPLLVILDD----------EALAFSCFTEL 889
Query: 266 MAEIRDNFIKSLDDSQCGITYKMEKVYSTLKDKDVELY-LKLQEQNIKPQFFAFRWLTLL 324
M + NF + + S ++ D EL+ L Q + +F +RW L
Sbjct: 890 MKRMNQNFPHG-----GAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRWFLLD 944
Query: 325 LSQEFLLPDVIRIWDSLFADD--NRFDFLLLVCCAMLMLIREQLLEG--DFTVNMRLLQD 380
+E + DV +W++++A + ++L + A++ + R+ +LE DFT ++ +
Sbjct: 945 FKRELVYDDVFLVWETIWAAKHVSSAHYVLFIALALVEVYRDIILENNMDFTDIIKFFNE 1004
Query: 381 YPIT-DVCQILQKAKEL 396
+ Q+L+ A++L
Sbjct: 1005 MAERHNTKQVLKLARDL 1021
>gi|148612840 RUN and TBC1 domain containing 2 isoform 3 [Homo
sapiens]
Length = 1093
Score = 53.9 bits (128), Expect = 2e-07
Identities = 49/197 (24%), Positives = 89/197 (45%), Gaps = 21/197 (10%)
Query: 206 AHWEVVERILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNSEWKEHAEADTFFCFTNL 265
A+ E + I+ Y + I YVQGM +++ PL EA F CFT L
Sbjct: 901 ANLEKLRNIMCSYIWQHIEIGYVQGMCDLLAPLLVILDD----------EALAFSCFTEL 950
Query: 266 MAEIRDNFIKSLDDSQCGITYKMEKVYSTLKDKDVELY-LKLQEQNIKPQFFAFRWLTLL 324
M + NF + + S ++ D EL+ L Q + +F +RW L
Sbjct: 951 MKRMNQNFPHG-----GAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRWFLLD 1005
Query: 325 LSQEFLLPDVIRIWDSLFADD--NRFDFLLLVCCAMLMLIREQLLEG--DFTVNMRLLQD 380
+E + DV +W++++A + ++L + A++ + R+ +LE DFT ++ +
Sbjct: 1006 FKRELVYDDVFLVWETIWAAKHVSSAHYVLFIALALVEVYRDIILENNMDFTDIIKFFNE 1065
Query: 381 YPIT-DVCQILQKAKEL 396
+ Q+L+ A++L
Sbjct: 1066 MAERHNTKQVLKLARDL 1082
>gi|90577164 RUN and TBC1 domain containing 2 isoform 2 [Homo sapiens]
Length = 1087
Score = 53.9 bits (128), Expect = 2e-07
Identities = 49/197 (24%), Positives = 89/197 (45%), Gaps = 21/197 (10%)
Query: 206 AHWEVVERILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNSEWKEHAEADTFFCFTNL 265
A+ E + I+ Y + I YVQGM +++ PL EA F CFT L
Sbjct: 895 ANLEKLRNIMCSYIWQHIEIGYVQGMCDLLAPLLVILDD----------EALAFSCFTEL 944
Query: 266 MAEIRDNFIKSLDDSQCGITYKMEKVYSTLKDKDVELY-LKLQEQNIKPQFFAFRWLTLL 324
M + NF + + S ++ D EL+ L Q + +F +RW L
Sbjct: 945 MKRMNQNFPHG-----GAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRWFLLD 999
Query: 325 LSQEFLLPDVIRIWDSLFADD--NRFDFLLLVCCAMLMLIREQLLEG--DFTVNMRLLQD 380
+E + DV +W++++A + ++L + A++ + R+ +LE DFT ++ +
Sbjct: 1000 FKRELVYDDVFLVWETIWAAKHVSSAHYVLFIALALVEVYRDIILENNMDFTDIIKFFNE 1059
Query: 381 YPIT-DVCQILQKAKEL 396
+ Q+L+ A++L
Sbjct: 1060 MAERHNTKQVLKLARDL 1076
>gi|90577167 RUN and TBC1 domain containing 2 isoform 1 [Homo sapiens]
Length = 1148
Score = 53.9 bits (128), Expect = 2e-07
Identities = 49/197 (24%), Positives = 89/197 (45%), Gaps = 21/197 (10%)
Query: 206 AHWEVVERILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNSEWKEHAEADTFFCFTNL 265
A+ E + I+ Y + I YVQGM +++ PL EA F CFT L
Sbjct: 956 ANLEKLRNIMCSYIWQHIEIGYVQGMCDLLAPLLVILDD----------EALAFSCFTEL 1005
Query: 266 MAEIRDNFIKSLDDSQCGITYKMEKVYSTLKDKDVELY-LKLQEQNIKPQFFAFRWLTLL 324
M + NF + + S ++ D EL+ L Q + +F +RW L
Sbjct: 1006 MKRMNQNFPHG-----GAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRWFLLD 1060
Query: 325 LSQEFLLPDVIRIWDSLFADD--NRFDFLLLVCCAMLMLIREQLLEG--DFTVNMRLLQD 380
+E + DV +W++++A + ++L + A++ + R+ +LE DFT ++ +
Sbjct: 1061 FKRELVYDDVFLVWETIWAAKHVSSAHYVLFIALALVEVYRDIILENNMDFTDIIKFFNE 1120
Query: 381 YPIT-DVCQILQKAKEL 396
+ Q+L+ A++L
Sbjct: 1121 MAERHNTKQVLKLARDL 1137
>gi|148806902 TBC1 domain family, member 12 [Homo sapiens]
Length = 775
Score = 50.1 bits (118), Expect = 4e-06
Identities = 43/174 (24%), Positives = 69/174 (39%), Gaps = 15/174 (8%)
Query: 209 EVVERILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNSEWKEHAEADTFFCFTNLMAE 268
+V+ IL Y P + YVQGM+ I L EAD F F NL+ +
Sbjct: 569 DVLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLE-----------EADAFIAFANLLNK 617
Query: 269 IRDNFIKSLDDSQCGITYKMEKVYSTLKDKDVELYLKLQEQNIKPQFFAFRWLTLLLSQE 328
+D S + +V+ ++ +L+L + ++ P + W+ L S+
Sbjct: 618 PCQLAFFRVDHSMMLKYFATFEVF--FEENLSKLFLHFKSYSLTPDIYLIDWIFTLYSKS 675
Query: 329 FLLPDVIRIWDSLFADDNRFDFLLLVCCAMLMLIREQLLEGDFTVNMRLLQDYP 382
L R+WD D +FL +L L + LL+ DF + L P
Sbjct: 676 LPLDLACRVWDVFCRDGE--EFLFRTGLGILRLYEDILLQMDFIHIAQFLTKLP 727
>gi|148612829 RUN and TBC1 domain containing 1 isoform 2 [Homo
sapiens]
Length = 1006
Score = 48.9 bits (115), Expect = 8e-06
Identities = 44/178 (24%), Positives = 81/178 (45%), Gaps = 21/178 (11%)
Query: 225 IAYVQGMNEIVGPLYYTFATDPNSEWKEHAEADTFFCFTNLMAEIRDNFIKSLDDSQCGI 284
+ YVQGM +++ PL T D + + CF++LM + NF + +
Sbjct: 833 VGYVQGMCDLLAPLLVTLDNDQLA----------YSCFSHLMKRMSQNF-----PNGGAM 877
Query: 285 TYKMEKVYSTLKDKDVELY-LKLQEQNIKPQFFAFRWLTLLLSQEFLLPDVIRIWDSLFA 343
+ S ++ D EL+ L Q + +F +RW L +E L DV +W+ ++A
Sbjct: 878 DTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRWFLLDFKRELLYEDVFAVWEVIWA 937
Query: 344 --DDNRFDFLLLVCCAMLMLIREQLLEG--DFTVNMRLLQD-YPITDVCQILQKAKEL 396
+ F+L + A++ RE + + DFT ++ + D +IL+ A++L
Sbjct: 938 ARHISSEHFVLFIALALVEAYREIIRDNNMDFTDIIKFFNERAEHHDAQEILRIARDL 995
>gi|148612795 RUN and TBC1 domain containing 1 isoform 1 [Homo
sapiens]
Length = 1051
Score = 48.9 bits (115), Expect = 8e-06
Identities = 44/178 (24%), Positives = 81/178 (45%), Gaps = 21/178 (11%)
Query: 225 IAYVQGMNEIVGPLYYTFATDPNSEWKEHAEADTFFCFTNLMAEIRDNFIKSLDDSQCGI 284
+ YVQGM +++ PL T D + + CF++LM + NF + +
Sbjct: 878 VGYVQGMCDLLAPLLVTLDNDQLA----------YSCFSHLMKRMSQNF-----PNGGAM 922
Query: 285 TYKMEKVYSTLKDKDVELY-LKLQEQNIKPQFFAFRWLTLLLSQEFLLPDVIRIWDSLFA 343
+ S ++ D EL+ L Q + +F +RW L +E L DV +W+ ++A
Sbjct: 923 DTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRWFLLDFKRELLYEDVFAVWEVIWA 982
Query: 344 --DDNRFDFLLLVCCAMLMLIREQLLEG--DFTVNMRLLQD-YPITDVCQILQKAKEL 396
+ F+L + A++ RE + + DFT ++ + D +IL+ A++L
Sbjct: 983 ARHISSEHFVLFIALALVEAYREIIRDNNMDFTDIIKFFNERAEHHDAQEILRIARDL 1040
>gi|164565381 TBC1 domain family, member 14 isoform b [Homo sapiens]
Length = 413
Score = 48.5 bits (114), Expect = 1e-05
Identities = 44/183 (24%), Positives = 75/183 (40%), Gaps = 21/183 (11%)
Query: 209 EVVERILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNSEWKEHAEADTFFCFTNLMAE 268
+++ IL Y P + YVQGM+ I L T AD F F+NL+ +
Sbjct: 208 DMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLDT-----------ADAFIAFSNLLNK 256
Query: 269 IRDNFIKSLDDSQCGITYKMEKVYSTLKDKDVELYLKLQEQNIKPQFFAFRWLTLLLSQE 328
+D + +V+ ++ +L+ ++ N+ P + W+ L S+
Sbjct: 257 PCQMAFFRVDHGLMLTYFAAFEVF--FEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKS 314
Query: 329 FLLPDVIRIWDSLFADDNRFDFLLLVCCAMLMLIREQLLEGDFTVNM-----RLLQDYPI 383
L RIWD D +FL +L L + L + DF ++M RL +D P
Sbjct: 315 LPLDLACRIWDVFCRDGE--EFLFRTALGILKLFEDILTKMDF-IHMAQFLTRLPEDLPA 371
Query: 384 TDV 386
++
Sbjct: 372 EEL 374
>gi|164565368 TBC1 domain family, member 14 isoform a [Homo sapiens]
Length = 693
Score = 48.5 bits (114), Expect = 1e-05
Identities = 44/183 (24%), Positives = 75/183 (40%), Gaps = 21/183 (11%)
Query: 209 EVVERILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNSEWKEHAEADTFFCFTNLMAE 268
+++ IL Y P + YVQGM+ I L T AD F F+NL+ +
Sbjct: 488 DMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLDT-----------ADAFIAFSNLLNK 536
Query: 269 IRDNFIKSLDDSQCGITYKMEKVYSTLKDKDVELYLKLQEQNIKPQFFAFRWLTLLLSQE 328
+D + +V+ ++ +L+ ++ N+ P + W+ L S+
Sbjct: 537 PCQMAFFRVDHGLMLTYFAAFEVF--FEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKS 594
Query: 329 FLLPDVIRIWDSLFADDNRFDFLLLVCCAMLMLIREQLLEGDFTVNM-----RLLQDYPI 383
L RIWD D +FL +L L + L + DF ++M RL +D P
Sbjct: 595 LPLDLACRIWDVFCRDGE--EFLFRTALGILKLFEDILTKMDF-IHMAQFLTRLPEDLPA 651
Query: 384 TDV 386
++
Sbjct: 652 EEL 654
>gi|164565366 TBC1 domain family, member 14 isoform a [Homo sapiens]
Length = 693
Score = 48.5 bits (114), Expect = 1e-05
Identities = 44/183 (24%), Positives = 75/183 (40%), Gaps = 21/183 (11%)
Query: 209 EVVERILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNSEWKEHAEADTFFCFTNLMAE 268
+++ IL Y P + YVQGM+ I L T AD F F+NL+ +
Sbjct: 488 DMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLDT-----------ADAFIAFSNLLNK 536
Query: 269 IRDNFIKSLDDSQCGITYKMEKVYSTLKDKDVELYLKLQEQNIKPQFFAFRWLTLLLSQE 328
+D + +V+ ++ +L+ ++ N+ P + W+ L S+
Sbjct: 537 PCQMAFFRVDHGLMLTYFAAFEVF--FEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKS 594
Query: 329 FLLPDVIRIWDSLFADDNRFDFLLLVCCAMLMLIREQLLEGDFTVNM-----RLLQDYPI 383
L RIWD D +FL +L L + L + DF ++M RL +D P
Sbjct: 595 LPLDLACRIWDVFCRDGE--EFLFRTALGILKLFEDILTKMDF-IHMAQFLTRLPEDLPA 651
Query: 384 TDV 386
++
Sbjct: 652 EEL 654
>gi|114688046 TBC1 domain family, member 4 [Homo sapiens]
Length = 1298
Score = 44.7 bits (104), Expect = 2e-04
Identities = 42/190 (22%), Positives = 76/190 (40%), Gaps = 16/190 (8%)
Query: 214 ILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNSEWKEHAEADTFFCFTNLMAEIRDNF 273
+L Y+ L+ + Y QG++ + G L + E F LM ++ F
Sbjct: 994 LLKAYSLLDKEVGYCQGISFVAGVLLLHMS-----------EEQAFEMLKFLMYDL--GF 1040
Query: 274 IKSLDDSQCGITYKMEKVYSTLKDKDVELYLKLQEQNIKPQFFAFRWLTLLLSQEFLLPD 333
K + +M ++ L D +LY L+E I P +A W L + +F L
Sbjct: 1041 RKQYRPDMMSLQIQMYQLSRLLHDYHRDLYNHLEENEISPSLYAAPWFLTLFASQFSLGF 1100
Query: 334 VIRIWDSLFADDNRFDF---LLLVCCAMLMLIREQLLEGDFTVNMRLLQDYPITDVCQIL 390
V R++D +F F L L+ +++ + E L D +++ +I+
Sbjct: 1101 VARVFDIIFLQGTEVIFKVALSLLSSQETLIMECESFENIVEFLKNTLPDMNTSEMEKII 1160
Query: 391 QKAKELQDSK 400
+ E+ SK
Sbjct: 1161 TQVFEMDISK 1170
>gi|68299759 ecotropic viral integration site 5 [Homo sapiens]
Length = 810
Score = 39.7 bits (91), Expect = 0.005
Identities = 35/162 (21%), Positives = 69/162 (42%), Gaps = 15/162 (9%)
Query: 209 EVVERILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNSEWKEHAEADTFFCFTNLMAE 268
EV+ ++ Y+ ++ + Y QG IVG L + E + F F LM +
Sbjct: 225 EVLFNVMKAYSLVDREVGYCQGSAFIVGLLLM-----------QMPEEEAFCVFVKLMQD 273
Query: 269 IRDNFIKSLDDSQCGITYKMEKVYSTLKDKDVELYLKLQEQNIKPQFFAFRWLTLLLSQE 328
R + ++ G+ M + +++ EL++ Q Q+ +A W +
Sbjct: 274 YRLRELFKPSMAELGLC--MYQFECMIQEHLPELFVHFQSQSFHTSMYASSWFLTIFLTT 331
Query: 329 FLLPDVIRIWDSLFADDNRFDFLLLVCCAMLMLIREQLLEGD 370
F LP RI+D ++ + + V A+L + + +L++ D
Sbjct: 332 FPLPIATRIFDIFMSEG--LEIVFRVGLALLQMNQAELMQLD 371
>gi|222352143 TBC1 domain family, member 2 [Homo sapiens]
Length = 917
Score = 39.3 bits (90), Expect = 0.006
Identities = 24/144 (16%), Positives = 57/144 (39%), Gaps = 22/144 (15%)
Query: 211 VERILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNSEWKEHAEADT-----FFCFTNL 265
+ R+L ++ NP I Y QG+N + + ++ W A +T ++C T
Sbjct: 695 LRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLEEEESAFWCLVAIVETIMPADYYCNTLT 754
Query: 266 MAEIRDNFIKSLDDSQCGITYKMEKVYSTLKDKDVELYLKLQEQNIKPQFFAFRWLTLLL 325
+++ ++ L L +K L L + ++ F W ++
Sbjct: 755 ASQVDQRVLQDL-----------------LSEKLPRLMAHLGQHHVDLSLVTFNWFLVVF 797
Query: 326 SQEFLLPDVIRIWDSLFADDNRFD 349
+ + ++R+WD+ + +++
Sbjct: 798 ADSLISNILLRVWDAFLYEGTKYN 821
>gi|50658061 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
[Homo sapiens]
Length = 1168
Score = 38.9 bits (89), Expect = 0.008
Identities = 31/129 (24%), Positives = 54/129 (41%), Gaps = 13/129 (10%)
Query: 214 ILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNSEWKEHAEADTFFCFTNLMAEIRDNF 273
IL Y+ L+ + Y QG++ + G L + E + F LM ++
Sbjct: 876 ILKAYSLLDQEVGYCQGLSFVAGILLLHMS-----------EEEAFKMLKFLMFDM--GL 922
Query: 274 IKSLDDSQCGITYKMEKVYSTLKDKDVELYLKLQEQNIKPQFFAFRWLTLLLSQEFLLPD 333
K + +M ++ L D +LY L+E I P +A W + + +F L
Sbjct: 923 RKQYRPDMIILQIQMYQLSRLLHDYHRDLYNHLEEHEIGPSLYAAPWFLTMFASQFPLGF 982
Query: 334 VIRIWDSLF 342
V R++D +F
Sbjct: 983 VARVFDMIF 991
>gi|118722351 growth hormone regulated TBC protein 1 [Homo sapiens]
Length = 336
Score = 38.5 bits (88), Expect = 0.011
Identities = 35/155 (22%), Positives = 62/155 (40%), Gaps = 15/155 (9%)
Query: 214 ILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNSEWKEHAEADTFFCFTNLMAEIRDNF 273
+L Y N G+ Y QGMN I G Y T + E ++F+ L+ I ++
Sbjct: 140 VLLAYGHHNQGVGYCQGMNFIAG--YLILIT--------NNEEESFWLLDALVGRILPDY 189
Query: 274 IKSLDDSQCGITYKMEKVYSTLKDKDVELYLKLQEQNIKPQFFAFRWLTLLLSQEFLLPD 333
+ G+ E + ++ K + ++ + RW L +
Sbjct: 190 ---YSPAMLGLKTDQEVLGELVRAKLPAVGALMERLGVLWTLLVSRWFICLFVDILPVET 246
Query: 334 VIRIWDSLFADDNRFDFLLLVCCAMLMLIREQLLE 368
V+RIWD LF + ++ F V ++ +E +LE
Sbjct: 247 VLRIWDCLFNEGSKIIF--RVALTLIKQHQELILE 279
>gi|229577000 ecotropic viral integration site 5-like isoform 1
[Homo sapiens]
Length = 805
Score = 38.1 bits (87), Expect = 0.014
Identities = 44/204 (21%), Positives = 82/204 (40%), Gaps = 21/204 (10%)
Query: 172 VARNRSGVTNMSSPH----KNSVPSSLNEYEVLPNGCEAHWEVVERILFIYAKLNPGIAY 227
V S + MSSP + + + E+E EV+ ++ Y+ ++ + Y
Sbjct: 136 VKNQYSELLKMSSPCEKLIRRDIARTYPEHEFFKGQDSLGQEVLFNVMKAYSLVDREVGY 195
Query: 228 VQGMNEIVGPLYYTFATDPNSEWKEHAEADTFFCFTNLMAEIRDNFIKSLDDSQCGI-TY 286
QG IVG L + E + F F LM E R + ++ G+ Y
Sbjct: 196 CQGSAFIVGLLL-----------MQMPEEEAFCVFVRLMQEYRLRELFKPSMAELGLCIY 244
Query: 287 KMEKVYSTLKDKDVELYLKLQEQNIKPQFFAFRWLTLLLSQEFLLPDVIRIWDSLFADDN 346
+ E + L+++ +L + Q+ +A W L F LP R++D +
Sbjct: 245 QFEYM---LQEQLPDLNTHFRSQSFHTSMYASSWFLTLFLTTFPLPVATRVFDIFMYEG- 300
Query: 347 RFDFLLLVCCAMLMLIREQLLEGD 370
+ + V A+L + + +L++ D
Sbjct: 301 -LEIVFRVGLALLQVNQAELMQLD 323
>gi|21687020 ecotropic viral integration site 5-like isoform 2 [Homo
sapiens]
Length = 794
Score = 38.1 bits (87), Expect = 0.014
Identities = 44/204 (21%), Positives = 82/204 (40%), Gaps = 21/204 (10%)
Query: 172 VARNRSGVTNMSSPH----KNSVPSSLNEYEVLPNGCEAHWEVVERILFIYAKLNPGIAY 227
V S + MSSP + + + E+E EV+ ++ Y+ ++ + Y
Sbjct: 136 VKNQYSELLKMSSPCEKLIRRDIARTYPEHEFFKGQDSLGQEVLFNVMKAYSLVDREVGY 195
Query: 228 VQGMNEIVGPLYYTFATDPNSEWKEHAEADTFFCFTNLMAEIRDNFIKSLDDSQCGI-TY 286
QG IVG L + E + F F LM E R + ++ G+ Y
Sbjct: 196 CQGSAFIVGLLL-----------MQMPEEEAFCVFVRLMQEYRLRELFKPSMAELGLCIY 244
Query: 287 KMEKVYSTLKDKDVELYLKLQEQNIKPQFFAFRWLTLLLSQEFLLPDVIRIWDSLFADDN 346
+ E + L+++ +L + Q+ +A W L F LP R++D +
Sbjct: 245 QFEYM---LQEQLPDLNTHFRSQSFHTSMYASSWFLTLFLTTFPLPVATRVFDIFMYEG- 300
Query: 347 RFDFLLLVCCAMLMLIREQLLEGD 370
+ + V A+L + + +L++ D
Sbjct: 301 -LEIVFRVGLALLQVNQAELMQLD 323
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,992,575
Number of Sequences: 37866
Number of extensions: 649318
Number of successful extensions: 1490
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 1400
Number of HSP's gapped (non-prelim): 61
length of query: 400
length of database: 18,247,518
effective HSP length: 104
effective length of query: 296
effective length of database: 14,309,454
effective search space: 4235598384
effective search space used: 4235598384
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.