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Search of human proteins with 189083802
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
(2175 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|189083802 myosin VIIA isoform 2 [Homo sapiens] 4383 0.0
gi|189083798 myosin VIIA isoform 1 [Homo sapiens] 4359 0.0
gi|189083800 myosin VIIA isoform 3 [Homo sapiens] 2350 0.0
gi|122937512 myosin VIIB [Homo sapiens] 2286 0.0
gi|154354979 myosin X [Homo sapiens] 647 0.0
gi|215982794 myosin VA isoform 2 [Homo sapiens] 582 e-165
gi|215982791 myosin VA isoform 1 [Homo sapiens] 582 e-165
gi|118402590 myosin XV [Homo sapiens] 573 e-163
gi|122937345 myosin VB [Homo sapiens] 566 e-161
gi|153945715 myosin VC [Homo sapiens] 554 e-157
gi|194328685 myosin IB isoform 1 [Homo sapiens] 525 e-148
gi|240120050 myosin IB isoform 1 [Homo sapiens] 525 e-148
gi|44889481 myosin IB isoform 2 [Homo sapiens] 514 e-145
gi|145275208 myosin IIIA [Homo sapiens] 507 e-143
gi|134288892 myosin IIIB isoform 2 [Homo sapiens] 506 e-142
gi|124494247 myosin IC isoform b [Homo sapiens] 505 e-142
gi|124494238 myosin IC isoform a [Homo sapiens] 505 e-142
gi|124494240 myosin IC isoform c [Homo sapiens] 505 e-142
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 504 e-142
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 503 e-142
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 497 e-140
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 497 e-140
gi|134288915 myosin IIIB isoform 1 [Homo sapiens] 495 e-139
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 494 e-139
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 494 e-139
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 493 e-139
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 490 e-138
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 489 e-138
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 483 e-136
gi|4885503 myosin IA [Homo sapiens] 483 e-136
>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
Length = 2175
Score = 4383 bits (11367), Expect = 0.0
Identities = 2175/2175 (100%), Positives = 2175/2175 (100%)
Query: 1 MVILQQGDHVWMDLRLGQEFDVPIGAVVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMH 60
MVILQQGDHVWMDLRLGQEFDVPIGAVVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMH
Sbjct: 1 MVILQQGDHVWMDLRLGQEFDVPIGAVVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMH 60
Query: 61 PTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIR 120
PTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIR
Sbjct: 61 PTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIR 120
Query: 121 QYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISG 180
QYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISG
Sbjct: 121 QYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISG 180
Query: 181 QHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKS 240
QHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKS
Sbjct: 181 QHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKS 240
Query: 241 RVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYAN 300
RVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYAN
Sbjct: 241 RVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYAN 300
Query: 301 IRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLE 360
IRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLE
Sbjct: 301 IRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLE 360
Query: 361 VNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYK 420
VNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYK
Sbjct: 361 VNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYK 420
Query: 421 PPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLE 480
PPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLE
Sbjct: 421 PPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLE 480
Query: 481 SIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIP 540
SIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIP
Sbjct: 481 SIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIP 540
Query: 541 PKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQADVAMG 600
PKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQADVAMG
Sbjct: 541 PKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQADVAMG 600
Query: 601 AETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSG 660
AETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSG
Sbjct: 601 AETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSG 660
Query: 661 MMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQ 720
MMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQ
Sbjct: 661 MMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQ 720
Query: 721 IGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRG 780
IGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRG
Sbjct: 721 IGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRG 780
Query: 781 HNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAV 840
HNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAV
Sbjct: 781 HNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAV 840
Query: 841 LTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQER 900
LTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQER
Sbjct: 841 LTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQER 900
Query: 901 LAQLAREDAERELKEKEAARRKKELLEQMERARHEPVNHSDMVDKMFGFLGTSGGLPGQE 960
LAQLAREDAERELKEKEAARRKKELLEQMERARHEPVNHSDMVDKMFGFLGTSGGLPGQE
Sbjct: 901 LAQLAREDAERELKEKEAARRKKELLEQMERARHEPVNHSDMVDKMFGFLGTSGGLPGQE 960
Query: 961 GQAPSGFEDLERGRREMVEEDLDAALPLPDEDEEDLSEYKFAKFAATYFQGTTTHSYTRR 1020
GQAPSGFEDLERGRREMVEEDLDAALPLPDEDEEDLSEYKFAKFAATYFQGTTTHSYTRR
Sbjct: 961 GQAPSGFEDLERGRREMVEEDLDAALPLPDEDEEDLSEYKFAKFAATYFQGTTTHSYTRR 1020
Query: 1021 PLKQPLLYHDDEGDQLAALAVWITILRFMGDLPEPKYHTAMSDGSEKIPVMTKIYETLGK 1080
PLKQPLLYHDDEGDQLAALAVWITILRFMGDLPEPKYHTAMSDGSEKIPVMTKIYETLGK
Sbjct: 1021 PLKQPLLYHDDEGDQLAALAVWITILRFMGDLPEPKYHTAMSDGSEKIPVMTKIYETLGK 1080
Query: 1081 KTYKRELQALQGEGEAQLPEGQKKSSVRHKLVHLTLKKKSKLTEEVTKRLHDGESTVQGN 1140
KTYKRELQALQGEGEAQLPEGQKKSSVRHKLVHLTLKKKSKLTEEVTKRLHDGESTVQGN
Sbjct: 1081 KTYKRELQALQGEGEAQLPEGQKKSSVRHKLVHLTLKKKSKLTEEVTKRLHDGESTVQGN 1140
Query: 1141 SMLEDRPTSNLEKLHFIIGNGILRPALRDEIYCQISKQLTHNPSKSSYARGWILVSLCVG 1200
SMLEDRPTSNLEKLHFIIGNGILRPALRDEIYCQISKQLTHNPSKSSYARGWILVSLCVG
Sbjct: 1141 SMLEDRPTSNLEKLHFIIGNGILRPALRDEIYCQISKQLTHNPSKSSYARGWILVSLCVG 1200
Query: 1201 CFAPSEKFVKYLRNFIHGGPPGYAPYCEERLRRTFVNGTRTQPPSWLELQATKSKKPIML 1260
CFAPSEKFVKYLRNFIHGGPPGYAPYCEERLRRTFVNGTRTQPPSWLELQATKSKKPIML
Sbjct: 1201 CFAPSEKFVKYLRNFIHGGPPGYAPYCEERLRRTFVNGTRTQPPSWLELQATKSKKPIML 1260
Query: 1261 PVTFMDGTTKTLLTDSATTAKELCNALADKISLKDRFGFSLYIALFDKVSSLGSGSDHVM 1320
PVTFMDGTTKTLLTDSATTAKELCNALADKISLKDRFGFSLYIALFDKVSSLGSGSDHVM
Sbjct: 1261 PVTFMDGTTKTLLTDSATTAKELCNALADKISLKDRFGFSLYIALFDKVSSLGSGSDHVM 1320
Query: 1321 DAISQCEQYAKEQGAQERNAPWRLFFRKEVFTPWHSPSEDNVATNLIYQQVVRGVKFGEY 1380
DAISQCEQYAKEQGAQERNAPWRLFFRKEVFTPWHSPSEDNVATNLIYQQVVRGVKFGEY
Sbjct: 1321 DAISQCEQYAKEQGAQERNAPWRLFFRKEVFTPWHSPSEDNVATNLIYQQVVRGVKFGEY 1380
Query: 1381 RCEKEDDLAELASQQYFVDYGSEMILERLLNLVPTYIPDREITPLKTLEKWAQLAIAAHK 1440
RCEKEDDLAELASQQYFVDYGSEMILERLLNLVPTYIPDREITPLKTLEKWAQLAIAAHK
Sbjct: 1381 RCEKEDDLAELASQQYFVDYGSEMILERLLNLVPTYIPDREITPLKTLEKWAQLAIAAHK 1440
Query: 1441 KGIYAQRRTDAQKVKEDVVSYARFKWPLLFSRFYEAYKFSGPSLPKNDVIVAVNWTGVYF 1500
KGIYAQRRTDAQKVKEDVVSYARFKWPLLFSRFYEAYKFSGPSLPKNDVIVAVNWTGVYF
Sbjct: 1441 KGIYAQRRTDAQKVKEDVVSYARFKWPLLFSRFYEAYKFSGPSLPKNDVIVAVNWTGVYF 1500
Query: 1501 VDEQEQVLLELSFPEIMAVSSSRGAKTTAPSFTLATIKGDEYTFTSSNAEDIRDLVVTFL 1560
VDEQEQVLLELSFPEIMAVSSSRGAKTTAPSFTLATIKGDEYTFTSSNAEDIRDLVVTFL
Sbjct: 1501 VDEQEQVLLELSFPEIMAVSSSRGAKTTAPSFTLATIKGDEYTFTSSNAEDIRDLVVTFL 1560
Query: 1561 EGLRKRSKYVVALQDNPNPAGEESGFLSFAKGDLIILDHDTGEQVMNSGWANGINERTKQ 1620
EGLRKRSKYVVALQDNPNPAGEESGFLSFAKGDLIILDHDTGEQVMNSGWANGINERTKQ
Sbjct: 1561 EGLRKRSKYVVALQDNPNPAGEESGFLSFAKGDLIILDHDTGEQVMNSGWANGINERTKQ 1620
Query: 1621 RGDFPTDSVYVMPTVTMPPREIVALVTMTPDQRQDVVRLLQLRTAEPEVRAKPYTLEEFS 1680
RGDFPTDSVYVMPTVTMPPREIVALVTMTPDQRQDVVRLLQLRTAEPEVRAKPYTLEEFS
Sbjct: 1621 RGDFPTDSVYVMPTVTMPPREIVALVTMTPDQRQDVVRLLQLRTAEPEVRAKPYTLEEFS 1680
Query: 1681 YDYFRPPPKHTLSRVMVSKARGKDRLWSHTREPLKQALLKKLLGSEELSQEACLAFIAVL 1740
YDYFRPPPKHTLSRVMVSKARGKDRLWSHTREPLKQALLKKLLGSEELSQEACLAFIAVL
Sbjct: 1681 YDYFRPPPKHTLSRVMVSKARGKDRLWSHTREPLKQALLKKLLGSEELSQEACLAFIAVL 1740
Query: 1741 KYMGDYPSKRTRSVNELTDQIFEGPLKAEPLKDEAYVQILKQLTDNHIRYSEERGWELLW 1800
KYMGDYPSKRTRSVNELTDQIFEGPLKAEPLKDEAYVQILKQLTDNHIRYSEERGWELLW
Sbjct: 1741 KYMGDYPSKRTRSVNELTDQIFEGPLKAEPLKDEAYVQILKQLTDNHIRYSEERGWELLW 1800
Query: 1801 LCTGLFPPSNILLPHVQRFLQSRKHCPLAIDCLQRLQKALRNGSRKYPPHLVEVEAIQHK 1860
LCTGLFPPSNILLPHVQRFLQSRKHCPLAIDCLQRLQKALRNGSRKYPPHLVEVEAIQHK
Sbjct: 1801 LCTGLFPPSNILLPHVQRFLQSRKHCPLAIDCLQRLQKALRNGSRKYPPHLVEVEAIQHK 1860
Query: 1861 TTQIFHKVYFPDDTDEAFEVESSTKAKDFCQNIATRLLLKSSEGFSLFVKIADKVLSVPE 1920
TTQIFHKVYFPDDTDEAFEVESSTKAKDFCQNIATRLLLKSSEGFSLFVKIADKVLSVPE
Sbjct: 1861 TTQIFHKVYFPDDTDEAFEVESSTKAKDFCQNIATRLLLKSSEGFSLFVKIADKVLSVPE 1920
Query: 1921 NDFFFDFVRHLTDWIKKARPIKDGIVPSLTYQVFFMKKLWTTTVPGKDPMADSIFHYYQE 1980
NDFFFDFVRHLTDWIKKARPIKDGIVPSLTYQVFFMKKLWTTTVPGKDPMADSIFHYYQE
Sbjct: 1921 NDFFFDFVRHLTDWIKKARPIKDGIVPSLTYQVFFMKKLWTTTVPGKDPMADSIFHYYQE 1980
Query: 1981 LPKYLRGYHKCTREEVLQLGALIYRVKFEEDKSYFPSIPKLLRELVPQDLIRQVSPDDWK 2040
LPKYLRGYHKCTREEVLQLGALIYRVKFEEDKSYFPSIPKLLRELVPQDLIRQVSPDDWK
Sbjct: 1981 LPKYLRGYHKCTREEVLQLGALIYRVKFEEDKSYFPSIPKLLRELVPQDLIRQVSPDDWK 2040
Query: 2041 RSIVAYFNKHAGKSKEEAKLAFLKLIFKWPTFGSAFFEQTTEPNFPEILLIAINKYGVSL 2100
RSIVAYFNKHAGKSKEEAKLAFLKLIFKWPTFGSAFFEQTTEPNFPEILLIAINKYGVSL
Sbjct: 2041 RSIVAYFNKHAGKSKEEAKLAFLKLIFKWPTFGSAFFEQTTEPNFPEILLIAINKYGVSL 2100
Query: 2101 IDPKTKDILTTHPFTKISNWSSGNTYFHITIGNLVRGSKLLCETSLGYKMDDLLTSYISQ 2160
IDPKTKDILTTHPFTKISNWSSGNTYFHITIGNLVRGSKLLCETSLGYKMDDLLTSYISQ
Sbjct: 2101 IDPKTKDILTTHPFTKISNWSSGNTYFHITIGNLVRGSKLLCETSLGYKMDDLLTSYISQ 2160
Query: 2161 MLTAMSKQRGSRSGK 2175
MLTAMSKQRGSRSGK
Sbjct: 2161 MLTAMSKQRGSRSGK 2175
>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
Length = 2215
Score = 4359 bits (11305), Expect = 0.0
Identities = 2175/2215 (98%), Positives = 2175/2215 (98%), Gaps = 40/2215 (1%)
Query: 1 MVILQQGDHVWMDLRLGQEFDVPIGAVVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMH 60
MVILQQGDHVWMDLRLGQEFDVPIGAVVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMH
Sbjct: 1 MVILQQGDHVWMDLRLGQEFDVPIGAVVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMH 60
Query: 61 PTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIR 120
PTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIR
Sbjct: 61 PTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIR 120
Query: 121 QYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISG 180
QYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISG
Sbjct: 121 QYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISG 180
Query: 181 QHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKS 240
QHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKS
Sbjct: 181 QHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKS 240
Query: 241 RVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYAN 300
RVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYAN
Sbjct: 241 RVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYAN 300
Query: 301 IRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLE 360
IRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLE
Sbjct: 301 IRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLE 360
Query: 361 VNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYK 420
VNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYK
Sbjct: 361 VNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYK 420
Query: 421 PPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLE 480
PPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLE
Sbjct: 421 PPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLE 480
Query: 481 SIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIP 540
SIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIP
Sbjct: 481 SIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIP 540
Query: 541 PKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQADVAMG 600
PKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQADVAMG
Sbjct: 541 PKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQADVAMG 600
Query: 601 AETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSG 660
AETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSG
Sbjct: 601 AETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSG 660
Query: 661 MMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQ 720
MMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQ
Sbjct: 661 MMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQ 720
Query: 721 IGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRG 780
IGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRG
Sbjct: 721 IGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRG 780
Query: 781 HNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAV 840
HNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAV
Sbjct: 781 HNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAV 840
Query: 841 LTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQER 900
LTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQER
Sbjct: 841 LTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQER 900
Query: 901 LAQLAREDAERELKEKEAARRKKELLEQMERARHEPVNHSDMVDKMFGFLGTSGGLPGQE 960
LAQLAREDAERELKEKEAARRKKELLEQMERARHEPVNHSDMVDKMFGFLGTSGGLPGQE
Sbjct: 901 LAQLAREDAERELKEKEAARRKKELLEQMERARHEPVNHSDMVDKMFGFLGTSGGLPGQE 960
Query: 961 GQAPSGFEDLERGRREMVEEDLDAALPLPDEDEEDLSEYKFAKFAATYFQGTTTHSYTRR 1020
GQAPSGFEDLERGRREMVEEDLDAALPLPDEDEEDLSEYKFAKFAATYFQGTTTHSYTRR
Sbjct: 961 GQAPSGFEDLERGRREMVEEDLDAALPLPDEDEEDLSEYKFAKFAATYFQGTTTHSYTRR 1020
Query: 1021 PLKQPLLYHDDEGDQLAALAVWITILRFMGDLPEPKYHTAMSDGSEKIPVMTKIYETLGK 1080
PLKQPLLYHDDEGDQLAALAVWITILRFMGDLPEPKYHTAMSDGSEKIPVMTKIYETLGK
Sbjct: 1021 PLKQPLLYHDDEGDQLAALAVWITILRFMGDLPEPKYHTAMSDGSEKIPVMTKIYETLGK 1080
Query: 1081 KTYKRELQALQGEGEAQLPEGQKKSSVRHKLVHLTLKKKSKLTEEVTKRLHDGESTVQGN 1140
KTYKRELQALQGEGEAQLPEGQKKSSVRHKLVHLTLKKKSKLTEEVTKRLHDGESTVQGN
Sbjct: 1081 KTYKRELQALQGEGEAQLPEGQKKSSVRHKLVHLTLKKKSKLTEEVTKRLHDGESTVQGN 1140
Query: 1141 SMLEDRPTSNLEKLHFIIGNGILRPALRDEIYCQISKQLTHNPSKSSYARGWILVSLCVG 1200
SMLEDRPTSNLEKLHFIIGNGILRPALRDEIYCQISKQLTHNPSKSSYARGWILVSLCVG
Sbjct: 1141 SMLEDRPTSNLEKLHFIIGNGILRPALRDEIYCQISKQLTHNPSKSSYARGWILVSLCVG 1200
Query: 1201 CFAPSEKFVKYLRNFIHGGPPGYAPYCEERLRRTFVNGTRTQPPSWLELQATKSKKPIML 1260
CFAPSEKFVKYLRNFIHGGPPGYAPYCEERLRRTFVNGTRTQPPSWLELQATKSKKPIML
Sbjct: 1201 CFAPSEKFVKYLRNFIHGGPPGYAPYCEERLRRTFVNGTRTQPPSWLELQATKSKKPIML 1260
Query: 1261 PVTFMDGTTKTLLTDSATTAKELCNALADKISLKDRFGFSLYIALFDKVSSLGSGSDHVM 1320
PVTFMDGTTKTLLTDSATTAKELCNALADKISLKDRFGFSLYIALFDKVSSLGSGSDHVM
Sbjct: 1261 PVTFMDGTTKTLLTDSATTAKELCNALADKISLKDRFGFSLYIALFDKVSSLGSGSDHVM 1320
Query: 1321 DAISQCEQYAKEQGAQERNAPWRLFFRKEVFTPWHSPSEDNVATNLIYQQVVRGVKFGEY 1380
DAISQCEQYAKEQGAQERNAPWRLFFRKEVFTPWHSPSEDNVATNLIYQQVVRGVKFGEY
Sbjct: 1321 DAISQCEQYAKEQGAQERNAPWRLFFRKEVFTPWHSPSEDNVATNLIYQQVVRGVKFGEY 1380
Query: 1381 RCEKEDDLAELASQQYFVDYGSEMILERLLNLVPTYIPDREITPLKTLEKWAQLAIAAHK 1440
RCEKEDDLAELASQQYFVDYGSEMILERLLNLVPTYIPDREITPLKTLEKWAQLAIAAHK
Sbjct: 1381 RCEKEDDLAELASQQYFVDYGSEMILERLLNLVPTYIPDREITPLKTLEKWAQLAIAAHK 1440
Query: 1441 KGIYAQRRTDAQKVKEDVVSYARFKWPLLFSRFYEAYKFSGPSLPKNDVIVAVNWTGVYF 1500
KGIYAQRRTDAQKVKEDVVSYARFKWPLLFSRFYEAYKFSGPSLPKNDVIVAVNWTGVYF
Sbjct: 1441 KGIYAQRRTDAQKVKEDVVSYARFKWPLLFSRFYEAYKFSGPSLPKNDVIVAVNWTGVYF 1500
Query: 1501 VDEQEQVLLELSFPEIMAVSSS-------------------------------------- 1522
VDEQEQVLLELSFPEIMAVSSS
Sbjct: 1501 VDEQEQVLLELSFPEIMAVSSSRECRVWLSLGCSDLGCAAPHSGWAGLTPAGPCSPCWSC 1560
Query: 1523 RGAKTTAPSFTLATIKGDEYTFTSSNAEDIRDLVVTFLEGLRKRSKYVVALQDNPNPAGE 1582
RGAKTTAPSFTLATIKGDEYTFTSSNAEDIRDLVVTFLEGLRKRSKYVVALQDNPNPAGE
Sbjct: 1561 RGAKTTAPSFTLATIKGDEYTFTSSNAEDIRDLVVTFLEGLRKRSKYVVALQDNPNPAGE 1620
Query: 1583 ESGFLSFAKGDLIILDHDTGEQVMNSGWANGINERTKQRGDFPTDSVYVMPTVTMPPREI 1642
ESGFLSFAKGDLIILDHDTGEQVMNSGWANGINERTKQRGDFPTDSVYVMPTVTMPPREI
Sbjct: 1621 ESGFLSFAKGDLIILDHDTGEQVMNSGWANGINERTKQRGDFPTDSVYVMPTVTMPPREI 1680
Query: 1643 VALVTMTPDQRQDVVRLLQLRTAEPEVRAKPYTLEEFSYDYFRPPPKHTLSRVMVSKARG 1702
VALVTMTPDQRQDVVRLLQLRTAEPEVRAKPYTLEEFSYDYFRPPPKHTLSRVMVSKARG
Sbjct: 1681 VALVTMTPDQRQDVVRLLQLRTAEPEVRAKPYTLEEFSYDYFRPPPKHTLSRVMVSKARG 1740
Query: 1703 KDRLWSHTREPLKQALLKKLLGSEELSQEACLAFIAVLKYMGDYPSKRTRSVNELTDQIF 1762
KDRLWSHTREPLKQALLKKLLGSEELSQEACLAFIAVLKYMGDYPSKRTRSVNELTDQIF
Sbjct: 1741 KDRLWSHTREPLKQALLKKLLGSEELSQEACLAFIAVLKYMGDYPSKRTRSVNELTDQIF 1800
Query: 1763 EGPLKAEPLKDEAYVQILKQLTDNHIRYSEERGWELLWLCTGLFPPSNILLPHVQRFLQS 1822
EGPLKAEPLKDEAYVQILKQLTDNHIRYSEERGWELLWLCTGLFPPSNILLPHVQRFLQS
Sbjct: 1801 EGPLKAEPLKDEAYVQILKQLTDNHIRYSEERGWELLWLCTGLFPPSNILLPHVQRFLQS 1860
Query: 1823 RKHCPLAIDCLQRLQKALRNGSRKYPPHLVEVEAIQHKTTQIFHKVYFPDDTDEAFEVES 1882
RKHCPLAIDCLQRLQKALRNGSRKYPPHLVEVEAIQHKTTQIFHKVYFPDDTDEAFEVES
Sbjct: 1861 RKHCPLAIDCLQRLQKALRNGSRKYPPHLVEVEAIQHKTTQIFHKVYFPDDTDEAFEVES 1920
Query: 1883 STKAKDFCQNIATRLLLKSSEGFSLFVKIADKVLSVPENDFFFDFVRHLTDWIKKARPIK 1942
STKAKDFCQNIATRLLLKSSEGFSLFVKIADKVLSVPENDFFFDFVRHLTDWIKKARPIK
Sbjct: 1921 STKAKDFCQNIATRLLLKSSEGFSLFVKIADKVLSVPENDFFFDFVRHLTDWIKKARPIK 1980
Query: 1943 DGIVPSLTYQVFFMKKLWTTTVPGKDPMADSIFHYYQELPKYLRGYHKCTREEVLQLGAL 2002
DGIVPSLTYQVFFMKKLWTTTVPGKDPMADSIFHYYQELPKYLRGYHKCTREEVLQLGAL
Sbjct: 1981 DGIVPSLTYQVFFMKKLWTTTVPGKDPMADSIFHYYQELPKYLRGYHKCTREEVLQLGAL 2040
Query: 2003 IYRVKFEEDKSYFPSIPKLLRELVPQDLIRQVSPDDWKRSIVAYFNKHAGKSKEEAKLAF 2062
IYRVKFEEDKSYFPSIPKLLRELVPQDLIRQVSPDDWKRSIVAYFNKHAGKSKEEAKLAF
Sbjct: 2041 IYRVKFEEDKSYFPSIPKLLRELVPQDLIRQVSPDDWKRSIVAYFNKHAGKSKEEAKLAF 2100
Query: 2063 LKLIFKWPTFGSAFFE--QTTEPNFPEILLIAINKYGVSLIDPKTKDILTTHPFTKISNW 2120
LKLIFKWPTFGSAFFE QTTEPNFPEILLIAINKYGVSLIDPKTKDILTTHPFTKISNW
Sbjct: 2101 LKLIFKWPTFGSAFFEVKQTTEPNFPEILLIAINKYGVSLIDPKTKDILTTHPFTKISNW 2160
Query: 2121 SSGNTYFHITIGNLVRGSKLLCETSLGYKMDDLLTSYISQMLTAMSKQRGSRSGK 2175
SSGNTYFHITIGNLVRGSKLLCETSLGYKMDDLLTSYISQMLTAMSKQRGSRSGK
Sbjct: 2161 SSGNTYFHITIGNLVRGSKLLCETSLGYKMDDLLTSYISQMLTAMSKQRGSRSGK 2215
>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
Length = 1204
Score = 2350 bits (6089), Expect = 0.0
Identities = 1173/1189 (98%), Positives = 1176/1189 (98%), Gaps = 9/1189 (0%)
Query: 1 MVILQQGDHVWMDLRLGQEFDVPIGAVVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMH 60
MVILQQGDHVWMDLRLGQEFDVPIGAVVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMH
Sbjct: 1 MVILQQGDHVWMDLRLGQEFDVPIGAVVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMH 60
Query: 61 PTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIR 120
PTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIR
Sbjct: 61 PTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIR 120
Query: 121 QYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISG 180
QYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISG
Sbjct: 121 QYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISG 180
Query: 181 QHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKS 240
QHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKS
Sbjct: 181 QHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKS 240
Query: 241 RVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYAN 300
RVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYAN
Sbjct: 241 RVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYAN 300
Query: 301 IRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLE 360
IRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLE
Sbjct: 301 IRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLE 360
Query: 361 VNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYK 420
VNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYK
Sbjct: 361 VNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYK 420
Query: 421 PPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLE 480
PPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLE
Sbjct: 421 PPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLE 480
Query: 481 SIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIP 540
SIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIP
Sbjct: 481 SIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIP 540
Query: 541 PKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQADVAMG 600
PKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQADVAMG
Sbjct: 541 PKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQADVAMG 600
Query: 601 AETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSG 660
AETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSG
Sbjct: 601 AETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSG 660
Query: 661 MMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQ 720
MMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQ
Sbjct: 661 MMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQ 720
Query: 721 IGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRG 780
IGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRG
Sbjct: 721 IGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRG 780
Query: 781 HNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAV 840
HNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAV
Sbjct: 781 HNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAV 840
Query: 841 LTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQER 900
LTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQER
Sbjct: 841 LTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQER 900
Query: 901 LAQLAREDAERELKEKEAARRKKELLEQMERARHEPVNHSDMVDKMFGFLGTSGGLPGQE 960
LAQLAREDAERELKEKEAARRKKELLEQMERARHEPVNHSDMVDKMFGFLGTSGGLPGQE
Sbjct: 901 LAQLAREDAERELKEKEAARRKKELLEQMERARHEPVNHSDMVDKMFGFLGTSGGLPGQE 960
Query: 961 GQAPSGFEDLERGRREMVEEDLDAALPLPDEDEEDLSEYKFAKFAATYFQGTTTHSYTRR 1020
GQAPSGFEDLERGRREMVEEDLDAALPLPDEDEEDLSEYKFAKFAATYFQGTTTHSYTRR
Sbjct: 961 GQAPSGFEDLERGRREMVEEDLDAALPLPDEDEEDLSEYKFAKFAATYFQGTTTHSYTRR 1020
Query: 1021 PLKQPLLYHDDEGDQLAALAVWITILRFMGDLPEPKYHTAMSDGSEKIPVMTKIYETLGK 1080
PLKQPLLYHDDEGDQLAALAVWITILRFMGDLPEPKYHTAMSDGSEKIPVMTKIYETLGK
Sbjct: 1021 PLKQPLLYHDDEGDQLAALAVWITILRFMGDLPEPKYHTAMSDGSEKIPVMTKIYETLGK 1080
Query: 1081 KTYKRELQALQGEGEAQLPEGQKKSSVRHKLVHLTLKKKSKLTEEVTKRLHDGESTVQGN 1140
KTYKRELQALQGEGEAQLPEGQKKSSVRHKLVHLTLKKKSKLTEEVTKRLHDGESTVQGN
Sbjct: 1081 KTYKRELQALQGEGEAQLPEGQKKSSVRHKLVHLTLKKKSKLTEEVTKRLHDGESTVQGN 1140
Query: 1141 SMLEDRPTSNLEKLHFIIGNGILRPALR---------DEIYCQISKQLT 1180
SMLEDRPTSNLEKLHFIIGNGILRPALR + CQ SK+L+
Sbjct: 1141 SMLEDRPTSNLEKLHFIIGNGILRPALRSVPESLLVAEWCLCQPSKRLS 1189
Score = 33.5 bits (75), Expect = 2.3
Identities = 27/86 (31%), Positives = 37/86 (43%), Gaps = 21/86 (24%)
Query: 1666 EPEVRAKPYTLEEFSYDYFRPPPKHTLSRVMVSKARGKDRLWSHTREPLKQALLKKLLGS 1725
E E Y +F+ YF+ H S+TR PLKQ L L
Sbjct: 991 EDEEDLSEYKFAKFAATYFQGTTTH-----------------SYTRRPLKQPL---LYHD 1030
Query: 1726 EELSQEACLA-FIAVLKYMGDYPSKR 1750
+E Q A LA +I +L++MGD P +
Sbjct: 1031 DEGDQLAALAVWITILRFMGDLPEPK 1056
>gi|122937512 myosin VIIB [Homo sapiens]
Length = 2116
Score = 2286 bits (5925), Expect = 0.0
Identities = 1164/2193 (53%), Positives = 1543/2193 (70%), Gaps = 115/2193 (5%)
Query: 7 GDHVWMDLRLGQEFDVPIGAVVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHG 66
GDHVW++ + V IG ++K G+V V DDE EHWI ++ + PMHP SV G
Sbjct: 7 GDHVWLEPPSTHKTGVAIGGIIKEAKPGKVLVEDDEGKEHWIRAEDFGVLSPMHPNSVQG 66
Query: 67 VEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKK 126
V+DMIRLGDLNEAG++ NLLIRY+ H IYTYTGSILVAVNP+Q+L +Y+ E ++ Y ++
Sbjct: 67 VDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQLYYSRH 126
Query: 127 IGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISGQHSWIE 186
+GE+PPH+FAIA+NCYF+MKRN RDQCCIISGESGAGKTE+TKLILQFLA ISGQHSWIE
Sbjct: 127 MGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATISGQHSWIE 186
Query: 187 QQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQA 246
QQVLEA PILEAFGNAKTIRNDNSSRFGKYIDI+FN G IEGA+IEQ+LLEKSRVCRQA
Sbjct: 187 QQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSRVCRQA 246
Query: 247 LDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSAMK 306
+ERNYH+FYCML G+S + K+ L LG S+Y+YL MGNC +CEG D+++YA+IRSAMK
Sbjct: 247 PEERNYHIFYCMLMGVSAEDKQLLSLGTPSEYHYLTMGNCTSCEGLNDAKDYAHIRSAMK 306
Query: 307 VLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPDL 366
+L F+D+E+W++ KLLAAILHLGN+ + A FENLDA +V+ +P+ T LLEV +L
Sbjct: 307 ILQFSDSESWDVIKLLAAILHLGNVGFMASVFENLDASDVMETPAFPTVMKLLEVQHQEL 366
Query: 367 MSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDV 426
CL T++ RGE V+ L+ QA D RDAFVKGIYG LF+WIV KINAAI+ PP+QD
Sbjct: 367 RDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFTPPAQDP 426
Query: 427 KNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLH 486
KN RR+IGLLDIFGFENF NSFEQLCINFANEHLQQFFV+HVF +EQEEY E+I W +
Sbjct: 427 KNVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYRSENISWDY 486
Query: 487 IEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKNNHE 546
I +TDN+ LD++A KPM+IISL+DEES+FP+GTD TML KLNS H N ++ PKN H+
Sbjct: 487 IHYTDNRPTLDLLALKPMSIISLLDEESRFPQGTDLTMLQKLNSVHANNKAFLQPKNIHD 546
Query: 547 TQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQADVA-------- 598
+FGI HFAG VYY+ +GFLEKNRD L DI+ LV+SS+NKF+++IF ++A
Sbjct: 547 ARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLREIFNLELAETKLGHGT 606
Query: 599 -----------MGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLF 647
A++ KR TL SQFK+SL+ LM+ L CQP+F+RCIKPNE+KKP+LF
Sbjct: 607 IRQAKAGNHLFKSADSNKRPSTLGSQFKQSLDQLMKILTNCQPYFIRCIKPNEYKKPLLF 666
Query: 648 DRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQR 707
DR LC+RQLRYSGMMET+ IR++G+PIRY+F EF +R+ VLLP QG LR
Sbjct: 667 DRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPNAMRMQLQGKLRQMTLG 726
Query: 708 MAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKL 767
+ + L T DW+ GKTKIFL+DH D LLEV+R + + + +QKV+RG++ R FL+
Sbjct: 727 ITDVWLRTDKDWKAGKTKIFLRDHQDTLLEVQRSQVLDRAALSIQKVLRGYRYRKEFLRQ 786
Query: 768 KNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAY 827
+ AA +Q WRG+ R+N+ L+ +GF RLQA+ RS+ L +QY+ RQR +Q QA CR Y
Sbjct: 787 RRAAVTLQAWWRGYCNRRNFKLILVGFERLQAIARSQPLARQYQAMRQRTVQLQALCRGY 846
Query: 828 LVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSAK 887
LVR+ + + AV+ +QA+ARGM ARR Q+ +A A + AE +K + + AK
Sbjct: 847 LVRQQVQAKRRAVVVIQAHARGMAARRNFQQRKAN------APLVIPAEGQKSQGALPAK 900
Query: 888 KAKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQMERARHEPVNHSDMVDKMF 947
K R+ ++ V ++MV+K+F
Sbjct: 901 K-----------------------------------------RRSIYDTVTDTEMVEKVF 919
Query: 948 GFLGTSGGLPGQEGQAPSGFEDLERGRREMVEEDLDAALPLPDEDEED---LSEYKFAKF 1004
GFL G GQEGQA FEDLE ++++E DLD +P+ +E EED L+EY F KF
Sbjct: 920 GFLPAMIG--GQEGQASPHFEDLESKTQKLLEVDLDT-VPMAEEPEEDVDGLAEYTFPKF 976
Query: 1005 AATYFQGTTTHSYTRRPLKQPLLYHDDEGDQLAALAVWITILRFMGDLPEPKYHTAMSDG 1064
A TYFQ + +H++ RRPL+ PLLYH+D+ D LAAL +W ILRFMGDLPEP + S
Sbjct: 977 AVTYFQKSASHTHIRRPLRYPLLYHEDDTDCLAALVIWNVILRFMGDLPEPVLYARSSQQ 1036
Query: 1065 SEKIPVMTKIYETLGKKTYKRELQALQGEGEAQLPEGQKKSSVRHKLVHLTLKKKSKLTE 1124
VM +I++TLG+ E AQ+P+ + +
Sbjct: 1037 GSS--VMRQIHDTLGR------------EHGAQVPQHSRSA------------------- 1063
Query: 1125 EVTKRLHDGESTVQGNSMLEDRPTSNLEKLHFIIGNGILRPALRDEIYCQISKQLTHNPS 1184
+V +L+ GE ++ + + DRP SNLEK+HFI+G ILRP+LRDEIYCQI KQL+ N
Sbjct: 1064 QVASQLNIGEEALEPDGLGADRPMSNLEKVHFIVGYAILRPSLRDEIYCQICKQLSENFK 1123
Query: 1185 KSSYARGWILVSLCVGCFAPSEKFVKYLRNFIHGGPPGYAPYCEERLRRTFVNGTRTQPP 1244
SS ARGWIL+SLC+GCF PSE+F+KYL NFI GP Y P+C ERLRRT+ NG R +PP
Sbjct: 1124 TSSLARGWILLSLCLGCFPPSERFMKYLLNFIGQGPATYGPFCAERLRRTYANGVRAEPP 1183
Query: 1245 SWLELQATKSKKPIMLPVTFMDGTTKTLLTDSATTAKELCNALADKISLKDRFGFSLYIA 1304
+WLELQA KSKK I + V G + T+ DSA+T++E+C +A K L D GFSL +A
Sbjct: 1184 TWLELQAVKSKKHIPIQVILATGESLTVPVDSASTSREMCMHIAHKQGLSDHLGFSLQVA 1243
Query: 1305 LFDKVSSLGSGSDHVMDAISQCEQYAKEQGAQERNAPWRLFFRKEVFTPWHSPSEDNVAT 1364
++DK SLGSG DH+MDAI++CEQ A+E+G +R +PWR++FRKE FTPWH ED V+T
Sbjct: 1244 VYDKFWSLGSGRDHMMDAIARCEQMAQERGESQRQSPWRIYFRKEFFTPWHDSREDPVST 1303
Query: 1365 NLIYQQVVRGVKFGEYRCEKEDDLAELASQQYFVDYGSEMILERLLNLVPTYIPDREITP 1424
LIY+QV+RGV GEY EKE++L EL ++ +V G+ + + L+P+ IP + +
Sbjct: 1304 ELIYRQVLRGVWSGEYSFEKEEELVELLARHCYVQLGASAESKAVQELLPSCIPHK-LYR 1362
Query: 1425 LKTLEKWAQLAIAAHKKGIYAQRRTDAQKVKEDVVSYARFKWPLLFSRFYEAYKFSGPSL 1484
K ++WA L AA K Y Q++ V+E VV AR +WPLLFSR +E SGP L
Sbjct: 1363 TKPPDRWASLVTAACAKAPYTQKQVTPLAVREQVVDAARLQWPLLFSRLFEVITLSGPRL 1422
Query: 1485 PKNDVIVAVNWTGVYFVDEQEQVLLELSFPEIMAVSSSRGAKTTAPSFTLATIKGDEYTF 1544
PK +I+AVNW G+ F+D+QE++LLELSFPE+M ++++R A+ L+T+ +EY F
Sbjct: 1423 PKTQLILAVNWKGLCFLDQQEKMLLELSFPEVMGLATNREAQG-GQRLLLSTMH-EEYEF 1480
Query: 1545 TSSNAEDIRDLVVTFLEGLRKRSKYVVALQDNPNPAGEESGFLSFAKGDLIILDHDTGEQ 1604
S ++ I +LV FLEGL++RS + +ALQD A +++ L+F KGDL++L G
Sbjct: 1481 VSPSSVAIAELVALFLEGLKERSIFAMALQDRK--ATDDTTLLAFKKGDLLVLTKKQG-L 1537
Query: 1605 VMNSGWANGINERTKQRGDFPTDSVYVMPTVTMPPREIVALVTMTPDQRQDVVRLLQLRT 1664
+ + W G N+RT + G P +Y +PTVT P ++++L+ M+P++R+ + Q
Sbjct: 1538 LASENWTLGQNDRTGKTGLVPMACLYTIPTVTKPSAQLLSLLAMSPEKRKLAAQEGQFTE 1597
Query: 1665 AEPEV--RAKPYTLEEFSYDYFRPPPKHTLSRVMVSKARGKDRLWSHTREPLKQALLKKL 1722
PE + K +TLEEFSY++FR P K +S ++ AR + LW+++ EPL+Q LLK++
Sbjct: 1598 PRPEEPPKEKLHTLEEFSYEFFRAPEKDMVSMAVLPLARARGHLWAYSCEPLRQPLLKRV 1657
Query: 1723 LGSEELSQEACLAFIAVLKYMGDYPSKRTRSVNELTDQIFEGPLKAEPLKDEAYVQILKQ 1782
+ +L AC F+A+L+YMGDYPS++ ELTDQIF L+ L+DE Y QILKQ
Sbjct: 1658 HANVDLWDIACQIFVAILRYMGDYPSRQAWPTLELTDQIFTLALQHPALQDEVYCQILKQ 1717
Query: 1783 LTDNHIRYSEERGWELLWLCTGLFPPSNILLPHVQRFLQSRKHCPLAIDCLQRLQKALRN 1842
LT N R+SEERGW+LLWLCTGLFPPS LLPH Q+F+ +R+ LA DC +R+QK LR
Sbjct: 1718 LTHNSNRHSEERGWQLLWLCTGLFPPSKGLLPHAQKFIDTRRGKLLAPDCSRRIQKVLRT 1777
Query: 1843 GSRKYPPHLVEVEAIQHKTTQIFHKVYFPDDTDEAFEVESSTKAKDFCQNIATRLLLKSS 1902
G RK PPH VEVEA + ++I HK+YFP+DT E EV ++T+ +D C +IATRL L S
Sbjct: 1778 GPRKQPPHQVEVEAAEQNVSRICHKIYFPNDTSEMLEVVANTRVRDVCDSIATRLQLASW 1837
Query: 1903 EGFSLFVKIADKVLSVPENDFFFDFVRHLTDWIKKARPIKDGIVPSLTYQVFFMKKLWTT 1962
EG SLF+KI+DKV+S E DFFFD +R ++DW+KK +P K+G +L YQV+FM+KLW
Sbjct: 1838 EGCSLFIKISDKVISQKEGDFFFDSLREVSDWVKKNKPQKEGAPVTLPYQVYFMRKLWLN 1897
Query: 1963 TVPGKDPMADSIFHYYQELPKYLRGYHKCTREEVLQLGALIYRVKFEEDKSYFPSIPKLL 2022
PGKD AD+I HY+QELPKYLRG+HKC+RE+ + L LIY+ +F D+S S+PK+L
Sbjct: 1898 ISPGKDVNADTILHYHQELPKYLRGFHKCSREDAIHLAGLIYKAQFNNDRSQLASVPKIL 1957
Query: 2023 RELVPQDLIRQVSPDDWKRSIVAYFNKHAGKSKEEAKLAFLKLIFKWPTFGSAFFE--QT 2080
RELVP++L R +S ++WK+SI+ ++KH K+ EEAK+AFLK I +WPTFGSAFFE QT
Sbjct: 1958 RELVPENLTRLMSSEEWKKSILLAYDKHKDKTVEEAKVAFLKWICRWPTFGSAFFEVKQT 2017
Query: 2081 TEPNFPEILLIAINKYGVSLIDPKTKDILTTHPFTKISNWSSGNTYFHITIGNLVRGSKL 2140
+EP++P+++LIAIN++GV LI PKTKD+LTT+PFTKIS+WSSG+TYFH+ +G+L RGS+L
Sbjct: 2018 SEPSYPDVILIAINRHGVLLIHPKTKDLLTTYPFTKISSWSSGSTYFHMALGSLGRGSRL 2077
Query: 2141 LCETSLGYKMDDLLTSYISQMLTAMSKQRGSRS 2173
LCETSLGYKMDDLLTSY+ Q+L+AM+KQRGS++
Sbjct: 2078 LCETSLGYKMDDLLTSYVQQLLSAMNKQRGSKA 2110
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 647 bits (1668), Expect = 0.0
Identities = 377/956 (39%), Positives = 554/956 (57%), Gaps = 96/956 (10%)
Query: 6 QGDHVWMDLRLGQEFDVPIGAVVKLCDSGQVQVVDDEDNEHWISPQNATHIK--PMHPTS 63
+G VW+ GQ F + V C G V D TH K MHPT+
Sbjct: 7 EGTRVWLREN-GQHFP----STVNSCAEGIVVFRTDYGQVFTYKQSTITHQKVTAMHPTN 61
Query: 64 VHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQ-LLSIYSPEHIRQY 122
GV+DM L +L+ I+ NL RY+ + IYTY GSIL +VNPYQ + +Y P + QY
Sbjct: 62 EEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQY 121
Query: 123 TNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISGQH 182
+ + +GE+PPHIFAIA+ CY + + +QC +ISGESGAGKTESTKLIL+FL+ IS Q
Sbjct: 122 SRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQQS 181
Query: 183 ---------SWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIE 233
S +E+ +LE++PI+EAFGNAKT+ N+NSSRFGK++ ++ ++G I+G +I
Sbjct: 182 LELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRIV 241
Query: 234 QYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRV 293
YLLEK+RV RQ ERNYH+FY +L G+ +++++ L +Y+YL C+ +
Sbjct: 242 DYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPENYHYLNQSGCVEDKTIS 301
Query: 294 DSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLA 353
D + + + +AM V+ F+ E E+S+LLA ILHLGN++ F +V F +L
Sbjct: 302 DQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIE-----FITAGGAQVSFKTALG 356
Query: 354 TAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDK 413
+A LL ++P L LT R++ RGE + TPL+ +QA+D RD+ +Y F W++ K
Sbjct: 357 RSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIKK 416
Query: 414 INAAIYKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLE 473
IN+ I ++D K SIG+LDIFGFENF VN FEQ IN+ANE LQ++F +H+F LE
Sbjct: 417 INSRI--KGNEDFK----SIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLE 470
Query: 474 QEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHK 533
Q EY E + W I++ DN + LD+I K + +++LI+EES FP+ TD+T+L KL+SQH
Sbjct: 471 QLEYSREGLVWEDIDWIDNGECLDLIEKK-LGLLALINEESHFPQATDSTLLEKLHSQHA 529
Query: 534 LNANYIPPK---NNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIK 590
N Y+ P+ NN FG+ H+AG V Y+ +G LEKNRDT D++ L+ SR FI
Sbjct: 530 NNHFYVKPRVAVNN----FGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIY 585
Query: 591 QIFQADVAMGAE------TRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKP 644
+F+ + + ++ R PT+SSQFK SL LM TL + PFFVRCIKPN K P
Sbjct: 586 DLFEHVSSRNNQDTLKCGSKHRRPTVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQKMP 645
Query: 645 MLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGT 704
FD+ + + QLRYSGM+ET+RIR+AGY +R F +F +RY+VL+ + D+RG
Sbjct: 646 DQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLA---LPEDVRGK 702
Query: 705 CQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNF 764
C + + ++ +WQ+GKTK+FL++ + LE R++ ++
Sbjct: 703 CTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVS------------------- 743
Query: 765 LKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARC 824
+AA +I+ H G RK QYR ++ Q
Sbjct: 744 ----HAAMVIRAHVLGFLARK-----------------------QYRKVLYCVVIIQKNY 776
Query: 825 RAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEM 884
RA+L+R+ F H A + Q RG IARR++++L AE R + EK + EEEK ++E
Sbjct: 777 RAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEK--REQEEKKKQEEEEKKKREE 834
Query: 885 SAK---KAKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQMERARHEPV 937
+ + + EAE + Q+ +++ E K ++ A +EL +Q E + E +
Sbjct: 835 EERERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEI 890
Score = 60.8 bits (146), Expect = 1e-08
Identities = 66/251 (26%), Positives = 109/251 (43%), Gaps = 20/251 (7%)
Query: 1163 LRPALRDEIYCQISKQLTHNPSKSSYAR--GWILVSLCVGC-FAPSEKFVKYLR---NFI 1216
LRP LRDE+YCQ+ KQ P S W +++ C+ C F PS +KYL+ I
Sbjct: 1599 LRP-LRDELYCQLIKQTNKVPHPGSVGNLYSWQILT-CLSCTFLPSRGILKYLKFHLKRI 1656
Query: 1217 HGGPPG-----YAPYCEERLRRTFVNGTRTQPPSWLELQATKSKKPIMLPVTFMDGTTKT 1271
PG YA + E L++T R PS E++A ++ + V G +
Sbjct: 1657 REQFPGSEMEKYALFTYESLKKT---KCREFVPSRDEIEALIHRQEMTSTVYCHGGGSCK 1713
Query: 1272 LLTDSATTAKELCNALADKISLKDRFGFSLYIALFDKVSSLGSGSDHVMDAISQCEQYAK 1331
+ +S TTA E+ L ++++D V V D +++ E+ A
Sbjct: 1714 ITINSHTTAGEVVEKLIRGLAMEDSRNMFALFEYNGHVDKAIESRTVVADVLAKFEKLAA 1773
Query: 1332 EQGAQERNAPWRLFFRKEVFTPWHSPSEDNVATNLIYQQVVRGVKFGEYRCEKED--DLA 1389
++ + PW+ +F+ F + +D+V +++Q V G + +E+ LA
Sbjct: 1774 T--SEVGDLPWKFYFKLYCFLDTDNVPKDSVEFAFMFEQAHEAVIHGHHPAPEENLQVLA 1831
Query: 1390 ELASQQYFVDY 1400
L Q DY
Sbjct: 1832 ALRLQYLQGDY 1842
Score = 54.3 bits (129), Expect = 1e-06
Identities = 100/457 (21%), Positives = 177/457 (38%), Gaps = 80/457 (17%)
Query: 1770 PLKDEAYVQILKQLTDNHIRYSEERG----WELLWLCTGLFPPSNILLP----HVQRFLQ 1821
PL+DE Y Q++KQ N + + G W++L + F PS +L H++R +
Sbjct: 1601 PLRDELYCQLIKQT--NKVPHPGSVGNLYSWQILTCLSCTFLPSRGILKYLKFHLKRIRE 1658
Query: 1822 SRKHCPLAIDCLQRLQKALRNGSRKYPPHLVEVEAIQHKTTQIFHKVYFPDDTDEAFEVE 1881
+ L + + R++ P E+EA+ H+ ++ VY +
Sbjct: 1659 QFPGSEMEKYALFTYESLKKTKCREFVPSRDEIEALIHRQ-EMTSTVYCHGGGSCKITIN 1717
Query: 1882 SSTKAKDFCQNIATRLLLKSSEG-FSLFVKIADKVLSVPENDFFFDFVRHLTDWIKKARP 1940
S T A + + + L ++ S F+LF ++ D L + K A
Sbjct: 1718 SHTTAGEVVEKLIRGLAMEDSRNMFALFEYNGHVDKAIESRTVVADV---LAKFEKLAAT 1774
Query: 1941 IKDGIVPSLTYQVFFMKKLWTTTVPGKDPMADSIFHYYQELPKYLRGYHKCTREEVLQLG 2000
+ G +P Y + L T VP KD + + F + Q + G+H E + L
Sbjct: 1775 SEVGDLPWKFYFKLYCF-LDTDNVP-KDSV-EFAFMFEQAHEAVIHGHHPAPEENLQVLA 1831
Query: 2001 ALIYRVKF-EEDKSYFPSIPKLLRELVPQDLIRQVSP----------------------- 2036
AL R+++ + D + +IP L Q L ++S
Sbjct: 1832 AL--RLQYLQGDYTLHAAIPPLEEVYSLQRLKARISQSTKTFTPCERLEKRRTSFLEGTL 1889
Query: 2037 --------------------DDW--------KRSIVAYFNKHAGKSKEEAKLAFLKLIFK 2068
D W + SI+ + K G ++E+A ++ LI +
Sbjct: 1890 RRSFRTGSVVRQKVEEEQMLDMWIKEEVSSARASIIDKWRKFQGMNQEQAMAKYMALIKE 1949
Query: 2069 WPTFGSAFFE-QTTEPNFPEILLIAINKYGVSLIDPKTKDILTTHPFTKISNWSS--GNT 2125
WP +GS F+ + E FP+ L + ++ VS+ L + I ++ + NT
Sbjct: 1950 WPGYGSTLFDVECKEGGFPQELWLGVSADAVSVYKRGEGRPLEVFQYEHILSFGAPLANT 2009
Query: 2126 YFHITIGNLVRGSKLLCETSLGYKMDDLLTSYISQML 2162
Y + V +LL ETS + L+ +YIS ++
Sbjct: 2010 YKIV-----VDERELLFETSEVVDVAKLMKAYISMIV 2041
>gi|215982794 myosin VA isoform 2 [Homo sapiens]
Length = 1828
Score = 582 bits (1501), Expect = e-165
Identities = 381/1044 (36%), Positives = 548/1044 (52%), Gaps = 105/1044 (10%)
Query: 40 DDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDH-LIYTYT 98
+ +D E+ + P+ +P + G D+ L L+E +L NL +R+ D LIYTY
Sbjct: 44 EGKDLEYHLDPKTKELPHLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYC 103
Query: 99 GSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISG 158
G +LVA+NPY+ L IY + I Y+ + +G+M PHIFA+A+ Y M R+ R+Q I+SG
Sbjct: 104 GIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSG 163
Query: 159 ESGAGKTESTKLILQFLAAISGQHSW--IEQQVLEATPILEAFGNAKTIRNDNSSRFGKY 216
ESGAGKT S K +++ A +SG S +E++VL + PI+E+ GNAKT RNDNSSRFGKY
Sbjct: 164 ESGAGKTVSAKYAMRYFATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKY 223
Query: 217 IDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQAS 276
I+I F+KR I GA + YLLEKSRV QA +ERNYH+FY + + K L LG A
Sbjct: 224 IEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNAD 283
Query: 277 DYNYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEAR 336
++NY G EG D++E A+ R A +L +++ I ++LA ILHLGN+ + +R
Sbjct: 284 NFNYTKQGGSPVIEGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSR 343
Query: 337 TFENLDACEV-LFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVR 395
+ D+C + L L+ V+ ++ L R L T ET P+S+ QA + R
Sbjct: 344 ---DADSCTIPPKHEPLCIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNAR 400
Query: 396 DAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCIN 455
DA K IY +LF WIVD +N A++ Q IG+LDI+GFE F +NSFEQ CIN
Sbjct: 401 DALAKHIYAKLFNWIVDNVNQALHSAVKQ-----HSFIGVLDIYGFETFEINSFEQFCIN 455
Query: 456 FANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESK 515
+ANE LQQ F HVFKLEQEEY E I W I+F DNQ +++I +K + I+ L+DEE K
Sbjct: 456 YANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIESK-LGILDLLDEECK 514
Query: 516 FPKGTDTTMLHKLNSQHKLNANYIPPKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHG 575
PKGTD T KL + H F I HFA V Y+ +GFLEKN+DT+
Sbjct: 515 MPKGTDDTWAQKLYNTHLNKCALFEKPRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFE 574
Query: 576 DIIQLVHSSRNKFIKQIFQAD---------VAMGAETRKRSP-----------------T 609
+ I+++ SS+ K + ++FQ D + G R+P T
Sbjct: 575 EQIKVLKSSKFKMLPELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKT 634
Query: 610 LSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRR 669
+ QF+ SL LLM TL A P +VRCIKPN+FK P FD V+QLR G++ETIRI
Sbjct: 635 VGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISA 694
Query: 670 AGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLK 729
AG+P R+++ EF RYRVL+ K D + TC+ + E ++ D +Q GKTKIF +
Sbjct: 695 AGFPSRWTYQEFFSRYRVLM---KQKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFR 751
Query: 730 DHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLK--------------------- 768
LE R + I +QK IRG+ R +L+++
Sbjct: 752 AGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKF 811
Query: 769 ----NAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYR--LARQRIIQFQA 822
AAT+IQ++WR + R+ Y + R + LQ+ R +YR L + + Q
Sbjct: 812 LRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQK 871
Query: 823 RCRAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEE----- 877
R R +L R ++ + A++ +Q R M+A+R ++L+ E +K+ + E
Sbjct: 872 RVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQ 931
Query: 878 ----------------EKLRKEMSAKKAKEEAERKHQERLAQLAREDAE----RELKEKE 917
EKL ++ E R ERL QL+ E+A+ R L +E
Sbjct: 932 LQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERL-QLSEEEAKVATGRVLSLQE 990
Query: 918 AARRKKELLEQMERARHEPVNHSDM----VDKMFGFLGTSGGLPGQEGQA------PSGF 967
+ ++ LEQ + H+D +++ L L QE +A
Sbjct: 991 EIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAK 1050
Query: 968 EDLERGRREMVEEDLDAALPLPDE 991
E E +++VEE L L DE
Sbjct: 1051 EMTETMEKKLVEETKQLELDLNDE 1074
>gi|215982791 myosin VA isoform 1 [Homo sapiens]
Length = 1855
Score = 582 bits (1501), Expect = e-165
Identities = 381/1044 (36%), Positives = 548/1044 (52%), Gaps = 105/1044 (10%)
Query: 40 DDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDH-LIYTYT 98
+ +D E+ + P+ +P + G D+ L L+E +L NL +R+ D LIYTY
Sbjct: 44 EGKDLEYHLDPKTKELPHLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYC 103
Query: 99 GSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISG 158
G +LVA+NPY+ L IY + I Y+ + +G+M PHIFA+A+ Y M R+ R+Q I+SG
Sbjct: 104 GIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSG 163
Query: 159 ESGAGKTESTKLILQFLAAISGQHSW--IEQQVLEATPILEAFGNAKTIRNDNSSRFGKY 216
ESGAGKT S K +++ A +SG S +E++VL + PI+E+ GNAKT RNDNSSRFGKY
Sbjct: 164 ESGAGKTVSAKYAMRYFATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKY 223
Query: 217 IDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQAS 276
I+I F+KR I GA + YLLEKSRV QA +ERNYH+FY + + K L LG A
Sbjct: 224 IEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNAD 283
Query: 277 DYNYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEAR 336
++NY G EG D++E A+ R A +L +++ I ++LA ILHLGN+ + +R
Sbjct: 284 NFNYTKQGGSPVIEGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSR 343
Query: 337 TFENLDACEV-LFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVR 395
+ D+C + L L+ V+ ++ L R L T ET P+S+ QA + R
Sbjct: 344 ---DADSCTIPPKHEPLCIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNAR 400
Query: 396 DAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCIN 455
DA K IY +LF WIVD +N A++ Q IG+LDI+GFE F +NSFEQ CIN
Sbjct: 401 DALAKHIYAKLFNWIVDNVNQALHSAVKQ-----HSFIGVLDIYGFETFEINSFEQFCIN 455
Query: 456 FANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESK 515
+ANE LQQ F HVFKLEQEEY E I W I+F DNQ +++I +K + I+ L+DEE K
Sbjct: 456 YANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIESK-LGILDLLDEECK 514
Query: 516 FPKGTDTTMLHKLNSQHKLNANYIPPKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHG 575
PKGTD T KL + H F I HFA V Y+ +GFLEKN+DT+
Sbjct: 515 MPKGTDDTWAQKLYNTHLNKCALFEKPRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFE 574
Query: 576 DIIQLVHSSRNKFIKQIFQAD---------VAMGAETRKRSP-----------------T 609
+ I+++ SS+ K + ++FQ D + G R+P T
Sbjct: 575 EQIKVLKSSKFKMLPELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKT 634
Query: 610 LSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRR 669
+ QF+ SL LLM TL A P +VRCIKPN+FK P FD V+QLR G++ETIRI
Sbjct: 635 VGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISA 694
Query: 670 AGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLK 729
AG+P R+++ EF RYRVL+ K D + TC+ + E ++ D +Q GKTKIF +
Sbjct: 695 AGFPSRWTYQEFFSRYRVLM---KQKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFR 751
Query: 730 DHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLK--------------------- 768
LE R + I +QK IRG+ R +L+++
Sbjct: 752 AGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKF 811
Query: 769 ----NAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYR--LARQRIIQFQA 822
AAT+IQ++WR + R+ Y + R + LQ+ R +YR L + + Q
Sbjct: 812 LRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQK 871
Query: 823 RCRAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEE----- 877
R R +L R ++ + A++ +Q R M+A+R ++L+ E +K+ + E
Sbjct: 872 RVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQ 931
Query: 878 ----------------EKLRKEMSAKKAKEEAERKHQERLAQLAREDAE----RELKEKE 917
EKL ++ E R ERL QL+ E+A+ R L +E
Sbjct: 932 LQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERL-QLSEEEAKVATGRVLSLQE 990
Query: 918 AARRKKELLEQMERARHEPVNHSDM----VDKMFGFLGTSGGLPGQEGQA------PSGF 967
+ ++ LEQ + H+D +++ L L QE +A
Sbjct: 991 EIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAK 1050
Query: 968 EDLERGRREMVEEDLDAALPLPDE 991
E E +++VEE L L DE
Sbjct: 1051 EMTETMEKKLVEETKQLELDLNDE 1074
>gi|118402590 myosin XV [Homo sapiens]
Length = 3530
Score = 573 bits (1476), Expect = e-163
Identities = 358/1007 (35%), Positives = 542/1007 (53%), Gaps = 137/1007 (13%)
Query: 66 GVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNK 125
GVEDM +L DL E +L NL IR+ +LIYTY GSILV+VNPYQ+ IY PE ++QY +
Sbjct: 1223 GVEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNGR 1282
Query: 126 KIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISGQHSWI 185
+GE PPH+FA+A+ + M ++QC IISGESG+GKTE+TKLIL++LAA++ + +
Sbjct: 1283 ALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMNQKREVM 1342
Query: 186 EQ-QVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCR 244
+Q ++LEATP+LE+FGNAKT+RNDNSSRFGK+++I F + G I GA QYLLEKSR+
Sbjct: 1343 QQIKILEATPLLESFGNAKTVRNDNSSRFGKFVEI-FLEGGVISGAITSQYLLEKSRIVF 1401
Query: 245 QALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSA 304
QA +ERNYH+FY +L G+ ++ L +A Y YL G G+ D+ ++ + +A
Sbjct: 1402 QAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKSDADDFRRLLAA 1461
Query: 305 MKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPP 364
M+VL F+ + I ++LA+ILHLGN+ +E + + V+ + + A LL+++P
Sbjct: 1462 MEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVAELLQISPE 1521
Query: 365 DLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQ 424
L +T + T E + TPL+ E A+D RDA K +Y LF W++ ++NA + P Q
Sbjct: 1522 GLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNALV--SPRQ 1579
Query: 425 DVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDW 484
D SI +LDI+GFE+ + NSFEQLCIN+ANE+LQ F + VF+ EQEEY E IDW
Sbjct: 1580 DT----LSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQIDW 1635
Query: 485 LHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKNN 544
I F DNQ +++I+ KP I+ ++D++ FP+ TD T L K + H N Y PK
Sbjct: 1636 QEITFADNQPCINLISLKPYGILRILDDQCCFPQATDHTFLQKCHYHHGANPLYSKPK-M 1694
Query: 545 HETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQADVAMGAETR 604
+F I H+AG V Y+ FL+KN D + D++ L SR + + +F + A R
Sbjct: 1695 PLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVAHLFSSHAPQAAPQR 1754
Query: 605 ----------KRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVR 654
++ T++++F++SL L+ + C P F+RC+KPN K+P LF+ + +
Sbjct: 1755 LGKSSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHKKEPGLFEPDVVMA 1814
Query: 655 QLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDL-RGTCQRMAEAVL 713
QLRYSG++ET+RIR+ G+P+R F F++RY L+ GD+ R+ + +
Sbjct: 1815 QLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLVALKHDLPANGDMCVSVLSRLCKVM- 1873
Query: 714 GTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATL 773
+ +++G +K+FLK+H LLE R+ + + LQ+ +RGF + F L++ L
Sbjct: 1874 --PNMYRVGVSKLFLKEHLYQLLESMREHVLNLAALTLQRCLRGFFIKRRFRSLRHKIIL 1931
Query: 774 IQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAF 833
+Q RG+ R Q+Y+ R+ +++F++ AY
Sbjct: 1932 LQSRARGYLAR-----------------------QRYQQMRRSLVKFRSLVHAY------ 1962
Query: 834 RHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEA 893
++RR + +LRAE WR + E L E+E+L K
Sbjct: 1963 -----------------VSRRRYLKLRAE--WRCQVEGALLWEQEELSK----------- 1992
Query: 894 ERKHQERLAQLAREDAERELKEKEAARRKKELLEQMERARHEPVNHSDMVDKMFGFLGTS 953
RE+ V H ++ ++ G L
Sbjct: 1993 -----------------REV---------------------VAVGHLEVPAELAGLLQAV 2014
Query: 954 GGLPGQEGQAPSGFEDLERGRREMVEEDLDAALPLPDEDEEDLSEYKFAKFAATYFQGTT 1013
GL Q P + R ++ + LPL D++ Y AKF +F+
Sbjct: 2015 AGL--GLAQVP----QVAPVRTPRLQAEPRVTLPL------DINNYPMAKFVQCHFKEPA 2062
Query: 1014 THSYTRRPLKQPLLYHDDEGDQLAALAVWITILRFMGDLPEPKYHTA 1060
T PL+ PL E A++++ ILRFMGD P H A
Sbjct: 2063 FGMLT-VPLRTPLTQLPAE-HHAEAVSIFKLILRFMGD---PHLHGA 2104
Score = 203 bits (517), Expect = 1e-51
Identities = 231/923 (25%), Positives = 390/923 (42%), Gaps = 180/923 (19%)
Query: 1338 RNAPWRLFFRKEVFTPWHSPSEDNVATNLIYQQVVRGVKFGEYRCEKEDDLAELASQQYF 1397
++APW++F RKEVF P S S V +L+++Q++ D L+E A +
Sbjct: 2685 QDAPWKIFLRKEVFYPKDSYSHP-VQLDLLFRQILH------------DTLSE-ACLRIS 2730
Query: 1398 VDYGSEMILERLLNLVPTYIPDREITPLKTLEKWAQLAIAAHKKGIYAQRRTDAQK---- 1453
D ERL K ++AQ + D QK
Sbjct: 2731 ED-------ERL-----------------------------RMKALFAQNQLDTQKPLVT 2754
Query: 1454 --VKEDVVSYARFKWPLLFSRFYEAYKFSGPSLPKNDVIVAVNWTGVYFV---------D 1502
VK VVS AR W + FSR + A G + ++AV+ G+ +
Sbjct: 2755 ESVKRAVVSTARDTWEVYFSRIFPATGSVGTGVQ----LLAVSHVGIKLLRMVKGGQEAG 2810
Query: 1503 EQEQVLLELSFPEIMAVSSSRGAKTTAPSFTLA--TIKGDEYTFTSSNAEDIRDLVVTFL 1560
Q +VL SF +I+ V T PS + + ++ S+ A ++ LV F+
Sbjct: 2811 GQLRVLRAYSFADILFV--------TMPSQNMLEFNLASEKVILFSARAHQVKTLVDDFI 2862
Query: 1561 EGLRKRSKYVVALQDNPNPAGEESGFLSFAKGDLIILDHDTGEQVMNS------------ 1608
L+K S YVVA++ N E+ L+F KGD+I L +V S
Sbjct: 2863 LELKKDSDYVVAVR---NFLPEDPALLAFHKGDIIHLQPLEPPRVGYSAGCVVRRKVVYL 2919
Query: 1609 ----------GWANG-INERTKQRGDFPTDSVY--VMPTVTMPPRE-------IVALVTM 1648
GW G I+ R G FP++ V P P E VA
Sbjct: 2920 EELRRRGPDFGWRFGTIHGRV---GRFPSELVQPAAAPDFLQLPTEPGRGRAAAVAAAVA 2976
Query: 1649 TPDQRQDVVRLLQLRTAEPEVRAK------------PYTLEEFSYDYFRPPPKHTLSRVM 1696
+ Q+V R R P VRA+ PYT+ EF+ YFR P + +
Sbjct: 2977 SAAAAQEVGR----RREGPPVRARSADHGEDALALPPYTMLEFAQKYFRDPQRRPQDGLR 3032
Query: 1697 VS-----KARGKDRLWSHTREPLKQALLKKLLGSEELSQEACLAFIAVLKYMGDYPSKRT 1751
+ ++R + + T+ PL+++L++ L LS+ A F+AV+++MGD P K
Sbjct: 3033 LKSKEPRESRTLEDMLCFTKTPLQESLIE--LSDSSLSKMATDMFLAVMRFMGDAPLKGQ 3090
Query: 1752 RSVNELTDQIFEGPLKAEPLKDEAYVQILKQLTDNHIRYSE--ERGWELLWLCTGLFPPS 1809
++ L + + + E ++DE Y Q++KQ+TDN + +RGW LL++ T S
Sbjct: 3091 SDLDVLCN-LLKLCGDHEVMRDECYCQVVKQITDNTSSKQDSCQRGWRLLYIVTAYHSCS 3149
Query: 1810 NILLPHVQRFLQSRKHCP------LAIDCLQRLQKALRNGSRKYPPHLVEVEAIQHKTTQ 1863
+L PH+ RFLQ P +A C Q LQK LR G R P +E+ A+ +
Sbjct: 3150 EVLHPHLTRFLQDVSRTPGLPFQGIAKACEQNLQKTLRFGGRLELPSSIELRAMLAGRSS 3209
Query: 1864 IFHKVYFPDDTDEAFEVESSTKAKDFCQNIATRLLLKSSEGFSLFVKIADKVLSVPENDF 1923
P + ++++ T A D + I + L E F+ +V V + ++
Sbjct: 3210 KRQLFLLPGGLERHLKIKTCTVALDVVEEICAEMALTRPEAFNEYVIFV--VTNRGQHVC 3267
Query: 1924 FFDFVRHLTDWIKKARPIKDGIVPSLTYQVFFMKKLWTTTVPGKDPMADSIFHYYQELPK 1983
++ D + + G Y ++F + LW + ++ + ++ HY Q LP
Sbjct: 3268 PLSRRAYILDVASEMEQVDGG------YMLWFRRVLWDQPLKFENELYVTM-HYNQVLPD 3320
Query: 1984 YLRGYHKCT---------REEVLQLGALIYRVKFEEDKSYFPSIPKLLRELVPQDLIRQV 2034
YL+G ++V +L +L +R K D Y PS+ + ++E +P L R
Sbjct: 3321 YLKGLFSSVPASRPSEQLLQQVSKLASLQHRAK---DHFYLPSV-REVQEYIPAQLYRTT 3376
Query: 2035 SPDDWKRSIVAYFNKHAGKSKEEAKLAFLKLIFKWPTFGSAFF--EQTTEPNFPEILLIA 2092
+ W + + + S +A+ FL L+ P FGS+FF + + P ++A
Sbjct: 3377 AGSTWLNLVSQHRQQTQALSPHQARAQFLGLLSALPMFGSSFFFIQSCSNIAVPAPCILA 3436
Query: 2093 INKYGVSLIDPKTKDILTTHPFTKISNW-------SSGNTYFHITIGNLVRGSKLLCETS 2145
IN G++ + +T +++ P +I + +S Y I +G++ L +
Sbjct: 3437 INHNGLNFLSTETHELMVKFPLKEIQSTRTQRPTANSSYPYVEIALGDVAAQRTLQLQLE 3496
Query: 2146 LGYKMDDLLTSYISQMLTAMSKQ 2168
G ++ ++ ++ +L+A K+
Sbjct: 3497 QGLELCRVVAVHVENLLSAHEKR 3519
Score = 82.4 bits (202), Expect = 4e-15
Identities = 56/182 (30%), Positives = 92/182 (50%), Gaps = 10/182 (5%)
Query: 1155 HFIIGNGILRPALRDEIYCQISKQLTHNPSKSSYARGWILVSLCVGCFAPSEKFVKYLRN 1214
++I+ G+ P LRDEI Q++ Q+ HN + + RGW+L++ C+ FAPS F KYL
Sbjct: 2111 NYIVQKGLAVPELRDEILAQLANQVWHNHNAHNAERGWLLLAACLSGFAPSPCFNKYLLK 2170
Query: 1215 FIHG-GPPGYAPYCEERLRRTF-------VNGTRTQPPSWLELQATKSKKPIMLPVTFMD 1266
F+ G G+ C+ RL + RT PP+ LE AT K + L V +
Sbjct: 2171 FVSDYGRNGFQAVCQHRLMQAMGRAQQQGSGAARTLPPTQLEWTATYEKASMALDVGCFN 2230
Query: 1267 GTTKTLLTDSATTAKELCNALADKISLKDRF-GFSLYIALFDKVSSLGSGSDHVMDAISQ 1325
G + S +T +E+ + L D + G+++ + + + L +G D+V+D +S
Sbjct: 2231 GDQFSCPVHSWSTGEEVAGDILRHRGLADGWRGWTVAMKNGVQWAEL-AGHDYVLDLVSD 2289
Query: 1326 CE 1327
E
Sbjct: 2290 LE 2291
Score = 65.1 bits (157), Expect = 7e-10
Identities = 108/459 (23%), Positives = 197/459 (42%), Gaps = 68/459 (14%)
Query: 1104 KSSVRHKLVHLTLKKKSKLTEEVTKRLHD--GESTVQGNSMLEDRPTSNLEKLHFIIGNG 1161
K+ ++ L+ L+ SK+ ++ + G++ ++G S L+ NL KL G+
Sbjct: 3052 KTPLQESLIELSDSSLSKMATDMFLAVMRFMGDAPLKGQSDLD--VLCNLLKL---CGD- 3105
Query: 1162 ILRPALRDEIYCQISKQLTHNPS--KSSYARGWILVSLCVGCFAPSEKFVKYLRNFIHG- 1218
+RDE YCQ+ KQ+T N S + S RGW L+ + + SE +L F+
Sbjct: 3106 --HEVMRDECYCQVVKQITDNTSSKQDSCQRGWRLLYIVTAYHSCSEVLHPHLTRFLQDV 3163
Query: 1219 ----GPP--GYAPYCEERLRRTFVNGTRTQPPSWLELQA----TKSKKPIMLPVTFMDGT 1268
G P G A CE+ L++T G R + PS +EL+A SK+ + L G
Sbjct: 3164 SRTPGLPFQGIAKACEQNLQKTLRFGGRLELPSSIELRAMLAGRSSKRQLFL---LPGGL 3220
Query: 1269 TKTLLTDSATTAKELCNALADKISLKDRFGFSLYIALFDKVSSLG------SGSDHVMDA 1322
+ L + T A ++ + +++L F+ Y+ V++ G S +++D
Sbjct: 3221 ERHLKIKTCTVALDVVEEICAEMALTRPEAFNEYVIFV--VTNRGQHVCPLSRRAYILDV 3278
Query: 1323 ISQCEQYAKEQGAQERNAPWRLFFRKEVFTPWHSP--SEDNVATNLIYQQVVRGVKFGEY 1380
S+ EQ + + L+FR+ + W P E+ + + Y QV+ G +
Sbjct: 3279 ASEMEQV---------DGGYMLWFRRVL---WDQPLKFENELYVTMHYNQVLPDYLKGLF 3326
Query: 1381 RC--------EKEDDLAELASQQYFVDYGSEMILERLLNLVPTYIPDREITPLKTLEKWA 1432
+ +++LAS Q+ + + V YIP ++ W
Sbjct: 3327 SSVPASRPSEQLLQQVSKLASLQH---RAKDHFYLPSVREVQEYIP-AQLYRTTAGSTWL 3382
Query: 1433 QLAIAAHKKGIYAQRRTDAQKVKEDVVSYARFKWPLLFSRFYEAYKFSGPSLPKNDVIVA 1492
L ++ H++ A A+ ++S P+ S F+ S ++P I+A
Sbjct: 3383 NL-VSQHRQQTQALSPHQARAQFLGLLS----ALPMFGSSFFFIQSCSNIAVPA-PCILA 3436
Query: 1493 VNWTGVYFVDEQEQVLLELSFPEIMAVSSSRGAKTTAPS 1531
+N G+ F+ + L+ + FP + + S+R + TA S
Sbjct: 3437 INHNGLNFLSTETHELM-VKFP-LKEIQSTRTQRPTANS 3473
Score = 53.9 bits (128), Expect = 2e-06
Identities = 51/208 (24%), Positives = 80/208 (38%), Gaps = 8/208 (3%)
Query: 1731 EACLAFIAVLKYMGDYPSKRTRSVNELTDQIFEGPLKAEPLKDEAYVQILKQLTDNHIRY 1790
EA F +L++MGD P N + I + L L+DE Q+ Q+ NH +
Sbjct: 2084 EAVSIFKLILRFMGD-PHLHGARENIFGNYIVQKGLAVPELRDEILAQLANQVWHNHNAH 2142
Query: 1791 SEERGWELLWLCTGLFPPSNILLPHVQRFLQSRKHCPLAIDCLQRLQKAL-------RNG 1843
+ ERGW LL C F PS ++ +F+ C RL +A+
Sbjct: 2143 NAERGWLLLAACLSGFAPSPCFNKYLLKFVSDYGRNGFQAVCQHRLMQAMGRAQQQGSGA 2202
Query: 1844 SRKYPPHLVEVEAIQHKTTQIFHKVYFPDDTDEAFEVESSTKAKDFCQNIATRLLLKSSE 1903
+R PP +E A K + F D ST + + R L
Sbjct: 2203 ARTLPPTQLEWTATYEKASMALDVGCFNGDQFSCPVHSWSTGEEVAGDILRHRGLADGWR 2262
Query: 1904 GFSLFVKIADKVLSVPENDFFFDFVRHL 1931
G+++ +K + + +D+ D V L
Sbjct: 2263 GWTVAMKNGVQWAELAGHDYVLDLVSDL 2290
>gi|122937345 myosin VB [Homo sapiens]
Length = 1848
Score = 566 bits (1459), Expect = e-161
Identities = 363/957 (37%), Positives = 526/957 (54%), Gaps = 62/957 (6%)
Query: 8 DHVWMDLRLGQEFDVPIGAVVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGV 67
D VW L +++ ++ Q+++ D+ E+ I Q +P + G
Sbjct: 19 DEVWRSAELTKDYKEGDKSL-------QLRLEDETILEYPIDVQRNQLPFLRNPDILVGE 71
Query: 68 EDMIRLGDLNEAGILRNLLIRYRD-HLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKK 126
D+ L L+E +L NL +R+ + + IYTY G +LVA+NPY+ L IY + I Y+ +
Sbjct: 72 NDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQN 131
Query: 127 IGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISGQHSW-- 184
+G+M PHIFA+A+ Y M R+ ++Q I+SGESGAGKT S K +++ A + G S
Sbjct: 132 MGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASETN 191
Query: 185 IEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCR 244
IE++VL ++PI+EA GNAKT RNDNSSRFGKYI I F+KR I GA + YLLEKSRV
Sbjct: 192 IEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLEKSRVVF 251
Query: 245 QALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSA 304
QA DERNYH+FY + + K+L L A D+ Y + G + EG D++++ R A
Sbjct: 252 QADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVDDAEDFEKTRQA 311
Query: 305 MKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPS---LATAASLLEV 361
+L ++ I K++A+ILHLG++ +A + D+C + SP L+ LL V
Sbjct: 312 FTLLGVKESHQMSIFKIIASILHLGSVAIQAE--RDGDSCSI--SPQDVYLSNFCRLLGV 367
Query: 362 NPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKP 421
+ L R L+T ET +S +Q ++ R+A K IY +LF WIV+ IN A++
Sbjct: 368 EHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKALHTS 427
Query: 422 PSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLES 481
Q IG+LDI+GFE F VNSFEQ CIN+ANE LQQ F HVFKLEQEEY E
Sbjct: 428 LKQ-----HSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQ 482
Query: 482 IDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPP 541
I W I+F DNQ +D+I K + I+ L+DEE K PKGTD KL +H + ++ P
Sbjct: 483 IPWTLIDFYDNQPCIDLIEAK-LGILDLLDEECKVPKGTDQNWAQKLYDRHSSSQHFQKP 541
Query: 542 KNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQAD----- 596
+ ++ T F I HFA V Y + GFLEKNRDT++ + I ++ +S+ + +F D
Sbjct: 542 RMSN-TAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDPVP 600
Query: 597 ------------------VAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKP 638
M ++ T+ QF+ SL LLM TL A P +VRCIKP
Sbjct: 601 ATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRCIKP 660
Query: 639 NEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQ 698
N+ K P FD V+QLR G++ETIRI AGYP R+++ +F RYRVL+ K
Sbjct: 661 NDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVK--KRELAN 718
Query: 699 GDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGF 758
D + C+ + E ++ D +Q G+TKIF + LE R I++QK +RG+
Sbjct: 719 TDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRGW 778
Query: 759 KDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMR--LGFLRLQALHRSRKLHQQYRLARQR 816
+ + +LK A +QR+ RGH R+ +R + LQ +R ++ Q Y+ R+
Sbjct: 779 LQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRARQAYQRVRRA 838
Query: 817 IIQFQARCRAYLVRKAFRHRLW--AVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRL 874
+ QA RA VR+ +R L T+Q + RG +ARR QRLR + A +M
Sbjct: 839 AVVIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRML- 897
Query: 875 AEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEK--EAARRKKELLEQM 929
K R+E+ A + E +H +RL + E+ +L+ K E + K L EQ+
Sbjct: 898 ----KARRELKALRI-EARSAEHLKRL-NVGMENKVVQLQRKIDEQNKEFKTLSEQL 948
>gi|153945715 myosin VC [Homo sapiens]
Length = 1742
Score = 554 bits (1427), Expect = e-157
Identities = 353/989 (35%), Positives = 533/989 (53%), Gaps = 86/989 (8%)
Query: 8 DHVWMDLRLGQEFDVPIGAVVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGV 67
+ VW + +++ V + L + G + ++ ++P++ ++ +P + G
Sbjct: 19 EEVWKSAEIAKDYRVGDKVLRLLLEDGT-------ELDYSVNPESLPPLR--NPDILVGE 69
Query: 68 EDMIRLGDLNEAGILRNLLIRYRDH-LIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKK 126
D+ L L+E +L NL IR+ + LIYTY+G ILVA+NPY+ L IY I Y+ +
Sbjct: 70 NDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQN 129
Query: 127 IGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAIS--GQHSW 184
+G+M PHIFA+A+ Y M RN+R+Q I+SGESGAGKT S + +++ A +S G ++
Sbjct: 130 MGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSNAH 189
Query: 185 IEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCR 244
+E +VL + PI EA GNAKT RNDNSSRFGKY +I F+++ I GA + YLLEKSRV
Sbjct: 190 VEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLEKSRVVF 249
Query: 245 QALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSA 304
Q+ +ERNYH+FY + + + K L LG A ++NY MG EG D E +
Sbjct: 250 QSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTVIEGVNDRAEMVETQKT 309
Query: 305 MKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPP 364
+L F + ++ K+LAAILHLGN+Q A E E L LL +
Sbjct: 310 FTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSE--DDSHLKVFCELLGLESG 367
Query: 365 DLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQ 424
+ L +R ++T ETV P++R QA++ RDA K IY LF +IV++IN A+ Q
Sbjct: 368 RVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQAL-----Q 422
Query: 425 DVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDW 484
IG+LDI+GFE F VNSFEQ CIN+ANE LQQ F HVFKLEQEEY E I W
Sbjct: 423 FSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDIPW 482
Query: 485 LHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKL-NSQHKLNANYIPPKN 543
I+F DNQ +D+I K M I+ L+DEE P GTD L KL N+ N + P+
Sbjct: 483 TLIDFYDNQPVIDLIEAK-MGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKPRM 541
Query: 544 NHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQ--------- 594
++ T F I HFA V Y+ +GFLEKNRDT++ +++++ +S+ FQ
Sbjct: 542 SN-TSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPTPPSPF 600
Query: 595 --------ADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPML 646
A + ++ T+ S+F+ SL LLM TL A P +VRCIKPN+ K P
Sbjct: 601 GSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDEKLPFE 660
Query: 647 FDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQ 706
FD V+QLR G++ETIRI YP R++++EF RY +L+ K D + C+
Sbjct: 661 FDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILM--TKQELSFSDKKEVCK 718
Query: 707 RMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLK 766
+ ++ + +Q GKTKIF + LE R + +++QK +RG+ R FL+
Sbjct: 719 VVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLR 778
Query: 767 LKNAATLIQRHWRG-HNCRKNYGLMRL----GFLRLQALHRSRKLHQQYRLARQRIIQFQ 821
+ AA +IQ+++RG RK + L + +Q R + Y+L R I Q
Sbjct: 779 ERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRMATITMQ 838
Query: 822 ARCRAYLVRKAFRHRL--WAVLTVQAYARGMIARRLHQRLR-----AEYLWRLEAEKMRL 874
A R +L R+ +R L + +Q YAR +ARR Q +R + +R++ + +L
Sbjct: 839 AYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKL 898
Query: 875 AEEEK-----------------------------LRKEMSAKKAKEEAERKH----QERL 901
++ K L K + ++ EE +++ +E+L
Sbjct: 899 EDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKL 958
Query: 902 AQLAREDAERELKEKEAARRKKELLEQME 930
A+L + ++E E ++++ + +E E+++
Sbjct: 959 AKLQKHNSELETQKEQIQLKLQEKTEELK 987
>gi|194328685 myosin IB isoform 1 [Homo sapiens]
Length = 1136
Score = 525 bits (1353), Expect = e-148
Identities = 320/855 (37%), Positives = 486/855 (56%), Gaps = 54/855 (6%)
Query: 66 GVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNK 125
GV DM+ L LNE + NL R+ IYTY GS++++VNPY+ L IYSPE + +Y N+
Sbjct: 16 GVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNR 75
Query: 126 KIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISGQHSWI 185
E+ PHIFA++D Y +++ +DQC +I+GESGAGKTE++KL++ ++AA+ G+ + +
Sbjct: 76 NFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEV 135
Query: 186 EQ---QVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRV 242
Q Q+L++ P+LEAFGNAKT+RNDNSSRFGKY+DI F+ +G G I YLLEKSRV
Sbjct: 136 NQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRV 195
Query: 243 CRQALDERNYHVFYCMLEGMSEDQKKKLGLGQ-ASDYNYLAMGNCITCEGRVDSQEYANI 301
+Q ERN+HVFY +L G SE+ KL L + S YNYL++ + G D+ + +
Sbjct: 196 VKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSA-KVNGVDDAANFRTV 254
Query: 302 RSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFEN-LDACEVLFSPSLATAASLLE 360
R+AM+++ F D E + ++AA+L LGN++++ + N LD ++ L L
Sbjct: 255 RNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTG 314
Query: 361 VNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYK 420
++ L + RT+ + E VST L+ QA RDA K +Y RLF W+V++IN +I
Sbjct: 315 IDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESI-- 372
Query: 421 PPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLE 480
K ++ +G+LDI+GFE F NSFEQ IN+ NE LQQ F+ K EQEEY E
Sbjct: 373 --KAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIRE 430
Query: 481 SIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFP-KGTDTTMLHKLN---------- 529
I+W HI++ +N D+I N I++++DEE P TD T L KLN
Sbjct: 431 DIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFE 490
Query: 530 SQHKLNANYIPPKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFI 589
S+ + ++ + + F I H+AG V Y+ +GF++KN D L+ D+ Q + + + I
Sbjct: 491 SRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASHALI 550
Query: 590 KQIFQADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDR 649
K +F + KR PT SQFK S+ LM+ L P ++RCIKPN+ K +F+
Sbjct: 551 KSLF-PEGNPAKINLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNE 609
Query: 650 HLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMA 709
L Q+RY G++E +R+RRAGY R ++ +ERY++L P +K G R + +
Sbjct: 610 ALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWK-GPARSGVEVLF 668
Query: 710 EAVLGTHDDWQIGKTKIFLKDHHDML-LEVERDKAITDRVILLQKVIRGFKDRSNFLKLK 768
+ +++ G++KIF+++ + LE R + + D L+QK+ RG+K R++FL +K
Sbjct: 669 NELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMK 728
Query: 769 NAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYL 828
+ +I +R + +K Y + L +Q+ R K + R ++ Q RC+
Sbjct: 729 KSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKIL-----RELKHQKRCKE-- 781
Query: 829 VRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAE------EEKLRK 882
AV T+ AY G ARR +RL+ E K +A K R+
Sbjct: 782 ----------AVTTIAAYWHGTQARRELRRLKEE-----ARNKHAIAVIWAYWLGSKARR 826
Query: 883 EMSAKKAKEEAERKH 897
E+ K+ KEEA RKH
Sbjct: 827 EL--KRLKEEARRKH 839
>gi|240120050 myosin IB isoform 1 [Homo sapiens]
Length = 1136
Score = 525 bits (1353), Expect = e-148
Identities = 320/855 (37%), Positives = 486/855 (56%), Gaps = 54/855 (6%)
Query: 66 GVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNK 125
GV DM+ L LNE + NL R+ IYTY GS++++VNPY+ L IYSPE + +Y N+
Sbjct: 16 GVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNR 75
Query: 126 KIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISGQHSWI 185
E+ PHIFA++D Y +++ +DQC +I+GESGAGKTE++KL++ ++AA+ G+ + +
Sbjct: 76 NFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEV 135
Query: 186 EQ---QVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRV 242
Q Q+L++ P+LEAFGNAKT+RNDNSSRFGKY+DI F+ +G G I YLLEKSRV
Sbjct: 136 NQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRV 195
Query: 243 CRQALDERNYHVFYCMLEGMSEDQKKKLGLGQ-ASDYNYLAMGNCITCEGRVDSQEYANI 301
+Q ERN+HVFY +L G SE+ KL L + S YNYL++ + G D+ + +
Sbjct: 196 VKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSA-KVNGVDDAANFRTV 254
Query: 302 RSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFEN-LDACEVLFSPSLATAASLLE 360
R+AM+++ F D E + ++AA+L LGN++++ + N LD ++ L L
Sbjct: 255 RNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTG 314
Query: 361 VNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYK 420
++ L + RT+ + E VST L+ QA RDA K +Y RLF W+V++IN +I
Sbjct: 315 IDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESI-- 372
Query: 421 PPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLE 480
K ++ +G+LDI+GFE F NSFEQ IN+ NE LQQ F+ K EQEEY E
Sbjct: 373 --KAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIRE 430
Query: 481 SIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFP-KGTDTTMLHKLN---------- 529
I+W HI++ +N D+I N I++++DEE P TD T L KLN
Sbjct: 431 DIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFE 490
Query: 530 SQHKLNANYIPPKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFI 589
S+ + ++ + + F I H+AG V Y+ +GF++KN D L+ D+ Q + + + I
Sbjct: 491 SRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASHALI 550
Query: 590 KQIFQADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDR 649
K +F + KR PT SQFK S+ LM+ L P ++RCIKPN+ K +F+
Sbjct: 551 KSLF-PEGNPAKINLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNE 609
Query: 650 HLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMA 709
L Q+RY G++E +R+RRAGY R ++ +ERY++L P +K G R + +
Sbjct: 610 ALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWK-GPARSGVEVLF 668
Query: 710 EAVLGTHDDWQIGKTKIFLKDHHDML-LEVERDKAITDRVILLQKVIRGFKDRSNFLKLK 768
+ +++ G++KIF+++ + LE R + + D L+QK+ RG+K R++FL +K
Sbjct: 669 NELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMK 728
Query: 769 NAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYL 828
+ +I +R + +K Y + L +Q+ R K + R ++ Q RC+
Sbjct: 729 KSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKIL-----RELKHQKRCKE-- 781
Query: 829 VRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAE------EEKLRK 882
AV T+ AY G ARR +RL+ E K +A K R+
Sbjct: 782 ----------AVTTIAAYWHGTQARRELRRLKEE-----ARNKHAIAVIWAYWLGSKARR 826
Query: 883 EMSAKKAKEEAERKH 897
E+ K+ KEEA RKH
Sbjct: 827 EL--KRLKEEARRKH 839
>gi|44889481 myosin IB isoform 2 [Homo sapiens]
Length = 1078
Score = 514 bits (1324), Expect = e-145
Identities = 303/810 (37%), Positives = 466/810 (57%), Gaps = 41/810 (5%)
Query: 66 GVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNK 125
GV DM+ L LNE + NL R+ IYTY GS++++VNPY+ L IYSPE + +Y N+
Sbjct: 16 GVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNR 75
Query: 126 KIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISGQHSWI 185
E+ PHIFA++D Y +++ +DQC +I+GESGAGKTE++KL++ ++AA+ G+ + +
Sbjct: 76 NFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEV 135
Query: 186 EQ---QVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRV 242
Q Q+L++ P+LEAFGNAKT+RNDNSSRFGKY+DI F+ +G G I YLLEKSRV
Sbjct: 136 NQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRV 195
Query: 243 CRQALDERNYHVFYCMLEGMSEDQKKKLGLGQ-ASDYNYLAMGNCITCEGRVDSQEYANI 301
+Q ERN+HVFY +L G SE+ KL L + S YNYL++ + G D+ + +
Sbjct: 196 VKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSA-KVNGVDDAANFRTV 254
Query: 302 RSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFEN-LDACEVLFSPSLATAASLLE 360
R+AM+++ F D E + ++AA+L LGN++++ + N LD ++ L L
Sbjct: 255 RNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTG 314
Query: 361 VNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYK 420
++ L + RT+ + E VST L+ QA RDA K +Y RLF W+V++IN +I
Sbjct: 315 IDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESI-- 372
Query: 421 PPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLE 480
K ++ +G+LDI+GFE F NSFEQ IN+ NE LQQ F+ K EQEEY E
Sbjct: 373 --KAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIRE 430
Query: 481 SIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFP-KGTDTTMLHKLN---------- 529
I+W HI++ +N D+I N I++++DEE P TD T L KLN
Sbjct: 431 DIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFE 490
Query: 530 SQHKLNANYIPPKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFI 589
S+ + ++ + + F I H+AG V Y+ +GF++KN D L+ D+ Q + + + I
Sbjct: 491 SRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASHALI 550
Query: 590 KQIFQADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDR 649
K +F + KR PT SQFK S+ LM+ L P ++RCIKPN+ K +F+
Sbjct: 551 KSLF-PEGNPAKINLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNE 609
Query: 650 HLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMA 709
L Q+RY G++E +R+RRAGY R ++ +ERY++L P +K G R + +
Sbjct: 610 ALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWK-GPARSGVEVLF 668
Query: 710 EAVLGTHDDWQIGKTKIFLKDHHDML-LEVERDKAITDRVILLQKVIRGFKDRSNFLKLK 768
+ +++ G++KIF+++ + LE R + + D L+QK+ RG+K R++FL +K
Sbjct: 669 NELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMK 728
Query: 769 NAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYL 828
+ +I +R + +K Y + L +Q+ R K + R ++ Q RC+
Sbjct: 729 KSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKIL-----RELKHQKRCKE-- 781
Query: 829 VRKAFRHRLWAVLTVQAYARGMIARRLHQR 858
AV T+ AY G RR +++
Sbjct: 782 ----------AVTTIAAYWHGTQVRREYRK 801
>gi|145275208 myosin IIIA [Homo sapiens]
Length = 1616
Score = 507 bits (1306), Expect = e-143
Identities = 307/775 (39%), Positives = 440/775 (56%), Gaps = 60/775 (7%)
Query: 62 TSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQ 121
+++ V+D+ L L+E + L Y IY Y G IL+A+NP+Q L +YS +H +
Sbjct: 335 SNLKDVDDLATLEILDENTVSEQLEKCYSRDQIYVYVGDILIALNPFQSLGLYSTKHSKL 394
Query: 122 YTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAIS-G 180
Y K PPHIFA+AD Y +M + DQC +ISGESGAGKTE+ L++Q L +
Sbjct: 395 YIGSKRTASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLVQQLTVLGKA 454
Query: 181 QHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKS 240
+ +++++L+ ++EAFGNA TI NDNSSRFGKY+++ F GA+ GA+I +YLLEKS
Sbjct: 455 NNRTLQEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQISEYLLEKS 514
Query: 241 RVCRQALDERNYHVFYCMLEGMSEDQKKKLG---LGQASDYNYLAMGNCITCEGRVDSQ- 296
RV QA+ E+N+H+FY + G++E KKKL L + YL + T + +++
Sbjct: 515 RVIHQAIGEKNFHIFYYIYAGLAE--KKKLAHYKLPENKPPRYLQNDHLRTVQDIMNNSF 572
Query: 297 ---EYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFEN-LDACEVLFSPSL 352
+Y I KV+ FT + I +LAAIL++GN+++ + E+ +D + +L
Sbjct: 573 YKSQYELIEQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQIDKSHISNHTAL 632
Query: 353 ATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVD 412
ASLL + +L LTS ++TRGET+ P + E+A DVRDA K +YGRLF WIV+
Sbjct: 633 ENCASLLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKTLYGRLFSWIVN 692
Query: 413 KINAAIYKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKL 472
IN+ + S SIG+LDIFGFENF NSFEQLCIN ANE +Q ++ +HVF
Sbjct: 693 CINSLLKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQIQYYYNQHVFAW 752
Query: 473 EQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQH 532
EQ EY E +D IE+ DN LDM KPM ++SL+DEES+FPK TD T++ K +
Sbjct: 753 EQNEYLNEDVDARVIEYEDNWPLLDMFLQKPMGLLSLLDEESRFPKATDQTLVEKF--EG 810
Query: 533 KLNANYIPPKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQI 592
L + Y E FGI+H+AG V Y GFL KNRDTL DI+ L+ SS N I+Q+
Sbjct: 811 NLKSQYFWRPKRMELSFGIHHYAGKVLYNASGFLAKNRDTLPTDIVLLLRSSDNSVIRQL 870
Query: 593 FQ----------------------------ADVAMG----------AETRKRSPTLSSQF 614
++A G T ++ T++S F
Sbjct: 871 VNHPLTKTGNLPHSKTKNVINYQMRTSEKLINLAKGDTGEATRHARETTNMKTQTVASYF 930
Query: 615 KRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPI 674
+ SL L+ + QP FVRCIKPN ++ +D+ + QLRY+G++ET RIRR G+
Sbjct: 931 RYSLMDLLSKMVVGQPHFVRCIKPNSERQARKYDKEKVLLQLRYTGILETARIRRLGFSH 990
Query: 675 RYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDM 734
R F F++RY +L K + + TC + E D+W +GKTK+FLK +H
Sbjct: 991 RILFANFIKRYYLLC--YKSSEEPRMSPDTCATILEK--AGLDNWALGKTKVFLKYYHVE 1046
Query: 735 LLEVERDKAITDRVILLQKVIRGFKDRSNFLKL----KNAATLIQRHWRGHNCRK 785
L + R +AI D++IL+Q +R F + K+ K +A +IQ RGH RK
Sbjct: 1047 QLNLMRKEAI-DKLILIQACVRAFLCSRRYQKIQEKRKESAIIIQSAARGHLVRK 1100
>gi|134288892 myosin IIIB isoform 2 [Homo sapiens]
Length = 1341
Score = 506 bits (1302), Expect = e-142
Identities = 301/808 (37%), Positives = 447/808 (55%), Gaps = 66/808 (8%)
Query: 37 QVVDDEDNEHWISPQNATHIKPMHPTSVHGVE------DMIRLGDLNEAGILRNLLIRYR 90
+V+ D+ +++ ++ + P V E D++ L L+E I+ L RY
Sbjct: 309 KVLQDQKHQNPVAKTRHERMHTRRPYHVEDAEKYCLEDDLVNLEVLDEDTIIHQLQKRYA 368
Query: 91 DHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSR 150
D LIYTY G IL+A+NP+Q LSIYSP+ R Y K PPHIFA AD Y M S+
Sbjct: 369 DLLIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKRASNPPHIFASADAAYQCMVTLSK 428
Query: 151 DQCCIISGESGAGKTESTKLILQFLAAIS-GQHSWIEQQVLEATPILEAFGNAKTIRNDN 209
DQC +ISGESG+GKTES LI+Q L + + + +++L+ ++EAFGN+ T NDN
Sbjct: 429 DQCIVISGESGSGKTESAHLIVQHLTFLGKANNQTLREKILQVNSLVEAFGNSCTAINDN 488
Query: 210 SSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQK-K 268
SSRFGKY+++ F G + GA+I +YLLEKSRV +QA E+N+H+FY + G+ +K
Sbjct: 489 SSRFGKYLEMMFTPTGVVMGARISEYLLEKSRVIKQAAREKNFHIFYYIYAGLHHQKKLS 548
Query: 269 KLGLGQASDYNYLAMGNCITCEGRVDSQEYAN----IRSAMKVLMFTDTENWEISKLLAA 324
L + Y+A + Y I+ +++ FTD E + ++LA
Sbjct: 549 DFRLPEEKPPRYIADETGRVMHDITSKESYRRQFEAIQHCFRIIGFTDKEVHSVYRILAG 608
Query: 325 ILHLGNLQYEARTFEN-LDACEVLFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVS 383
IL++GN+++ A + ++ D EV + +L AAS+L ++P +L LTS ++TRGET+
Sbjct: 609 ILNIGNIEFAAISSQHQTDKSEVPNAEALQNAASVLCISPEELQEALTSHCVVTRGETII 668
Query: 384 TPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRSIGLLDIFGFEN 443
+ ++A DVRDA K +YGRLF WIV++IN + + ++G+LDIFGFEN
Sbjct: 669 RANTVDRAADVRDAMSKALYGRLFSWIVNRINTLLQPDENICSAGGGMNVGILDIFGFEN 728
Query: 444 FAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKP 503
F NSFEQLCIN ANE +Q +F +HVF LEQ EY E ID + +E+ DN+ LDM KP
Sbjct: 729 FQRNSFEQLCINIANEQIQYYFNQHVFALEQMEYQNEGIDAVPVEYEDNRPLLDMFLQKP 788
Query: 504 MNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKNNHETQFGINHFAGIVYYETQ 563
+ +++L+DEES+FP+ TD T++ K + L Y E FGI H+AG V Y+
Sbjct: 789 LGLLALLDEESRFPQATDQTLVDKF--EDNLRCKYFWRPKGVELCFGIQHYAGKVLYDAS 846
Query: 564 GFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQADVAMG---AETRKR-------------- 606
G LEKNRDTL D++ ++ +S N ++Q+F + A+TR R
Sbjct: 847 GVLEKNRDTLPADVVVVLRTSENMLLQQLFSIPLTKTGNLAQTRARITVASSSLPPHFSA 906
Query: 607 ---------------------SPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPM 645
T++S F+ SL L+ + QP FVRCIKPN+ ++ +
Sbjct: 907 GKAKVDTLEVIRHPEETTNMKRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREAL 966
Query: 646 LFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTC 705
F R + QLR +G++ET+ IRR GY R F EFV+RY L A+
Sbjct: 967 QFSRERVLAQLRSTGILETVSIRRQGYSHRILFEEFVKRYYYL------AFTAHQTPLAS 1020
Query: 706 QRMAEAVL--GTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSN 763
+ A+L D W +GKTK+FLK +H L + + + RV++LQ +G+
Sbjct: 1021 KESCVAILEKSRLDHWVLGKTKVFLKYYHVEQLNLLL-REVIGRVVVLQAYTKGWLGARR 1079
Query: 764 FLKLK----NAATLIQRHWRGHNCRKNY 787
+ K++ A IQ WRG++ R+ +
Sbjct: 1080 YKKVREKREKGAIAIQSAWRGYDARRKF 1107
>gi|124494247 myosin IC isoform b [Homo sapiens]
Length = 1044
Score = 505 bits (1300), Expect = e-142
Identities = 296/743 (39%), Positives = 429/743 (57%), Gaps = 47/743 (6%)
Query: 66 GVEDMIRLGDL-NEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTN 124
GV+D + L + +EA + NL R+R++LIYTY G +LV+VNPY+ L IYS +H+ +Y
Sbjct: 28 GVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRG 87
Query: 125 KKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLA---AISGQ 181
E+PPH+FA+AD Y ++ RDQ +ISGESGAGKTE+TK +LQF A +
Sbjct: 88 VSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER 147
Query: 182 HSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSR 241
+ ++L++ P+LEAFGNAKT+RNDNSSRFGKY+D+ F+ +GA G I YLLEKSR
Sbjct: 148 GGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSR 207
Query: 242 VCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQ-ASDYNYLAMGNCITCEGRVDSQEYAN 300
V Q ERN+H+FY +LEG E+ ++LGL + Y YL G C D ++
Sbjct: 208 VVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKV 267
Query: 301 IRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLE 360
+R A+ V+ FT+ E ++ ++A++LHLGN+ + A N +V L LL
Sbjct: 268 VRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESN---AQVTTENQLKYLTRLLS 324
Query: 361 VNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYK 420
V L LT R +I +GE + +PL+ EQA RDA K +Y R F W+V KIN ++
Sbjct: 325 VEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSL-- 382
Query: 421 PPSQDVKN----SRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEE 476
S+DV++ S +GLLDI+GFE F NSFEQ CIN+ NE LQQ F+ K EQEE
Sbjct: 383 -ASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEE 441
Query: 477 YDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFP-KGTDTTMLHKLNSQHKLN 535
Y+ E I W +++ +N+ D++ K IIS++DEE P + TD T L KL K +
Sbjct: 442 YEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHH 501
Query: 536 ANYIPPKNNHET--------QFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNK 587
+++ K + +F + H+AG V Y GFL+KN D L ++ + + SS+N
Sbjct: 502 PHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNP 561
Query: 588 FIKQIFQADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLF 647
+ Q F +KR T+++QFK SL L+ L + +P +VRCIKPN+ K+P F
Sbjct: 562 IMSQCFDRS---ELSDKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPGRF 618
Query: 648 DRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQR 707
D L Q++Y G++E +R+RRAG+ R + F++RY+ L P P + G
Sbjct: 619 DEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGV--- 675
Query: 708 MAEAVLGTH-----DDWQIGKTKIFLKDHHDML-----LEVERDKAITDRVILLQKVIRG 757
AVL H +++++G+TKIF++ + LEV R T +Q RG
Sbjct: 676 ---AVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATK----IQAAWRG 728
Query: 758 FKDRSNFLKLKNAATLIQRHWRG 780
F R FL++K +A IQ WRG
Sbjct: 729 FHWRQKFLRVKRSAICIQSWWRG 751
>gi|124494238 myosin IC isoform a [Homo sapiens]
Length = 1063
Score = 505 bits (1300), Expect = e-142
Identities = 296/743 (39%), Positives = 429/743 (57%), Gaps = 47/743 (6%)
Query: 66 GVEDMIRLGDL-NEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTN 124
GV+D + L + +EA + NL R+R++LIYTY G +LV+VNPY+ L IYS +H+ +Y
Sbjct: 47 GVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRG 106
Query: 125 KKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLA---AISGQ 181
E+PPH+FA+AD Y ++ RDQ +ISGESGAGKTE+TK +LQF A +
Sbjct: 107 VSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER 166
Query: 182 HSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSR 241
+ ++L++ P+LEAFGNAKT+RNDNSSRFGKY+D+ F+ +GA G I YLLEKSR
Sbjct: 167 GGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSR 226
Query: 242 VCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQ-ASDYNYLAMGNCITCEGRVDSQEYAN 300
V Q ERN+H+FY +LEG E+ ++LGL + Y YL G C D ++
Sbjct: 227 VVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKV 286
Query: 301 IRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLE 360
+R A+ V+ FT+ E ++ ++A++LHLGN+ + A N +V L LL
Sbjct: 287 VRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESN---AQVTTENQLKYLTRLLS 343
Query: 361 VNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYK 420
V L LT R +I +GE + +PL+ EQA RDA K +Y R F W+V KIN ++
Sbjct: 344 VEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSL-- 401
Query: 421 PPSQDVKN----SRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEE 476
S+DV++ S +GLLDI+GFE F NSFEQ CIN+ NE LQQ F+ K EQEE
Sbjct: 402 -ASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEE 460
Query: 477 YDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFP-KGTDTTMLHKLNSQHKLN 535
Y+ E I W +++ +N+ D++ K IIS++DEE P + TD T L KL K +
Sbjct: 461 YEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHH 520
Query: 536 ANYIPPKNNHET--------QFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNK 587
+++ K + +F + H+AG V Y GFL+KN D L ++ + + SS+N
Sbjct: 521 PHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNP 580
Query: 588 FIKQIFQADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLF 647
+ Q F +KR T+++QFK SL L+ L + +P +VRCIKPN+ K+P F
Sbjct: 581 IMSQCFDRS---ELSDKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPGRF 637
Query: 648 DRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQR 707
D L Q++Y G++E +R+RRAG+ R + F++RY+ L P P + G
Sbjct: 638 DEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGV--- 694
Query: 708 MAEAVLGTH-----DDWQIGKTKIFLKDHHDML-----LEVERDKAITDRVILLQKVIRG 757
AVL H +++++G+TKIF++ + LEV R T +Q RG
Sbjct: 695 ---AVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATK----IQAAWRG 747
Query: 758 FKDRSNFLKLKNAATLIQRHWRG 780
F R FL++K +A IQ WRG
Sbjct: 748 FHWRQKFLRVKRSAICIQSWWRG 770
>gi|124494240 myosin IC isoform c [Homo sapiens]
Length = 1028
Score = 505 bits (1300), Expect = e-142
Identities = 296/743 (39%), Positives = 429/743 (57%), Gaps = 47/743 (6%)
Query: 66 GVEDMIRLGDL-NEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTN 124
GV+D + L + +EA + NL R+R++LIYTY G +LV+VNPY+ L IYS +H+ +Y
Sbjct: 12 GVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRG 71
Query: 125 KKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLA---AISGQ 181
E+PPH+FA+AD Y ++ RDQ +ISGESGAGKTE+TK +LQF A +
Sbjct: 72 VSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER 131
Query: 182 HSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSR 241
+ ++L++ P+LEAFGNAKT+RNDNSSRFGKY+D+ F+ +GA G I YLLEKSR
Sbjct: 132 GGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSR 191
Query: 242 VCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQ-ASDYNYLAMGNCITCEGRVDSQEYAN 300
V Q ERN+H+FY +LEG E+ ++LGL + Y YL G C D ++
Sbjct: 192 VVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKV 251
Query: 301 IRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLE 360
+R A+ V+ FT+ E ++ ++A++LHLGN+ + A N +V L LL
Sbjct: 252 VRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESN---AQVTTENQLKYLTRLLS 308
Query: 361 VNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYK 420
V L LT R +I +GE + +PL+ EQA RDA K +Y R F W+V KIN ++
Sbjct: 309 VEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSL-- 366
Query: 421 PPSQDVKN----SRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEE 476
S+DV++ S +GLLDI+GFE F NSFEQ CIN+ NE LQQ F+ K EQEE
Sbjct: 367 -ASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEE 425
Query: 477 YDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFP-KGTDTTMLHKLNSQHKLN 535
Y+ E I W +++ +N+ D++ K IIS++DEE P + TD T L KL K +
Sbjct: 426 YEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHH 485
Query: 536 ANYIPPKNNHET--------QFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNK 587
+++ K + +F + H+AG V Y GFL+KN D L ++ + + SS+N
Sbjct: 486 PHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNP 545
Query: 588 FIKQIFQADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLF 647
+ Q F +KR T+++QFK SL L+ L + +P +VRCIKPN+ K+P F
Sbjct: 546 IMSQCFDRS---ELSDKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPGRF 602
Query: 648 DRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQR 707
D L Q++Y G++E +R+RRAG+ R + F++RY+ L P P + G
Sbjct: 603 DEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGV--- 659
Query: 708 MAEAVLGTH-----DDWQIGKTKIFLKDHHDML-----LEVERDKAITDRVILLQKVIRG 757
AVL H +++++G+TKIF++ + LEV R T +Q RG
Sbjct: 660 ---AVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATK----IQAAWRG 712
Query: 758 FKDRSNFLKLKNAATLIQRHWRG 780
F R FL++K +A IQ WRG
Sbjct: 713 FHWRQKFLRVKRSAICIQSWWRG 735
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 504 bits (1298), Expect = e-142
Identities = 339/958 (35%), Positives = 520/958 (54%), Gaps = 69/958 (7%)
Query: 26 AVVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNL 85
A+V+L ++G+ V+ +D I+ M+P VEDM L LNEA +L NL
Sbjct: 54 AIVELVENGKKVKVNKDD------------IQKMNPPKFSKVEDMAELTCLNEASVLHNL 101
Query: 86 LIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNM 145
RY LIYTY+G V +NPY+ L IYS E + Y KK EMPPHI+AI D Y +M
Sbjct: 102 KERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSM 161
Query: 146 KRNSRDQCCIISGESGAGKTESTKLILQFLAAISGQH------SWIEQQVLEATPILEAF 199
++ DQ + +GESGAGKTE+TK ++Q+LA ++ H +E+Q+L+A PILEAF
Sbjct: 162 MQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKKDQGELERQLLQANPILEAF 221
Query: 200 GNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYCML 259
GNAKT++NDNSSRFGK+I I+F+ G I GA IE YLLEKSR RQA +ER +H+FY +L
Sbjct: 222 GNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLL 281
Query: 260 EGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTENWEIS 319
G E K L L + Y +L+ G+ +T G+ D + AM+++ + E +
Sbjct: 282 SGAGEHLKTDLLLEPYNKYRFLSNGH-VTIPGQQDKDMFQETMEAMRIMGIPEEEQMGLL 340
Query: 320 KLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPDL-MSCLTSRTLITR 378
++++ +L LGN+ ++ N D + + + + LL +N D LT R + R
Sbjct: 341 RVISGVLQLGNIVFKKE--RNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGR 398
Query: 379 GETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRSIGLLDI 438
+ V ++EQA +A K Y R+F W+V +IN A+ K Q IG+LDI
Sbjct: 399 -DYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDKTKRQGAS----FIGILDI 453
Query: 439 FGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEF-TDNQDALD 497
GFE F +NSFEQLCIN+ NE LQQ F +F LEQEEY E I+W I+F D Q +D
Sbjct: 454 AGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCID 513
Query: 498 MIANK--PMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKN-NHETQFGINHF 554
+I P I++L+DEE FPK TD + + K+ + + + PK + F I H+
Sbjct: 514 LIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQEQGTHPKFQKPKQLKDKADFCIIHY 573
Query: 555 AGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQ-ADVAMGAE----------- 602
AG V Y+ +L KN D L+ +I L+H S +KF+ ++++ D +G +
Sbjct: 574 AGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRIIGLDQVAGMSETALP 633
Query: 603 ----TRK-RSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLR 657
TRK T+ +K L LM TL P FVRCI PN KK D HL + QLR
Sbjct: 634 GAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLR 693
Query: 658 YSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHD 717
+G++E IRI R G+P R F EF +RY +L P P D + C M +A+ +
Sbjct: 694 CNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKGFM-DGKQACVLMIKALELDSN 752
Query: 718 DWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAAT---LI 774
++IG++K+F + LE ERD ITD +I Q RG+ R F K + T ++
Sbjct: 753 LYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVL 812
Query: 775 QRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFR 834
QR+ + +N+ RL F +++ L + + ++ + +++ + + + A
Sbjct: 813 QRNCAAYLKLRNWQWWRL-FTKVKPLLQVSRQEEEMMAKEEELVKVREK------QLAAE 865
Query: 835 HRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRL------AEEEKLRKEMSAKK 888
+RL + T+Q+ +L ++L+AE EAE++R E E++ ++ A+
Sbjct: 866 NRLTEMETLQSQLMAE-KLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARV 924
Query: 889 AKEEAERKH---QERLAQLAREDAERELKEKEAARRKKELLEQMERARHEPVNHSDMV 943
+EE +H +++ Q ++ E +L+E+E+AR+K +L + A+ + + ++
Sbjct: 925 EEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQII 982
Score = 31.6 bits (70), Expect = 8.9
Identities = 35/146 (23%), Positives = 63/146 (43%), Gaps = 18/146 (12%)
Query: 866 RLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQE-RLAQLAREDAERELKEKEAA----- 919
R + E+ + KL++ K+K +A E ++AQL E + E KE++AA
Sbjct: 1780 RQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQL-EEQLDNETKERQAACKQVR 1838
Query: 920 ---RRKKELLEQMERARHEPVNHSDMVDKMFGFLGTSGGLPGQEGQAPSGFEDLERGR-- 974
++ K++L Q++ R + D DK S L + Q E+ +R
Sbjct: 1839 RTEKKLKDVLLQVDDERRNAEQYKDQADK------ASTRLKQLKRQLEEAEEEAQRANAS 1892
Query: 975 REMVEEDLDAALPLPDEDEEDLSEYK 1000
R ++ +L+ A D ++S K
Sbjct: 1893 RRKLQRELEDATETADAMNREVSSLK 1918
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 503 bits (1295), Expect = e-142
Identities = 374/1194 (31%), Positives = 594/1194 (49%), Gaps = 142/1194 (11%)
Query: 27 VVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNLL 86
+V+L ++G+ +V+ +D I+ M+P VEDM L LNEA +L NL
Sbjct: 59 MVELAENGKKAMVNKDD------------IQKMNPPKFSKVEDMAELTCLNEASVLHNLK 106
Query: 87 IRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMK 146
RY LIYTY+G V +NPY+ L IYS I Y KK EMPPHI+AI+++ Y M
Sbjct: 107 DRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKKRHEMPPHIYAISESAYRCML 166
Query: 147 RNSRDQCCIISGESGAGKTESTKLILQFLAAISGQHSW---------IEQQVLEATPILE 197
++ DQ + +GESGAGKTE+TK ++Q+LA ++ H +E+Q+L+A PILE
Sbjct: 167 QDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKGRKDHNIPGELERQLLQANPILE 226
Query: 198 AFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYC 257
+FGNAKT++NDNSSRFGK+I I+F+ G I GA IE YLLEKSR RQA DER +H+FY
Sbjct: 227 SFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQ 286
Query: 258 MLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTENWE 317
+L G E K L L ++Y +L+ G I G+ D + AM ++ F+ E
Sbjct: 287 LLSGAGEHLKSDLLLEGFNNYRFLSNG-YIPIPGQQDKDNFQETMEAMHIMGFSHEEILS 345
Query: 318 ISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPDLMSCLTSRTLIT 377
+ K+++++L GN+ ++ N D + + LL +N + + + +
Sbjct: 346 MLKVVSSVLQFGNISFKKE--RNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKV 403
Query: 378 RGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRSIGLLD 437
+ V ++EQA +A K Y RLF W+V +IN A+ + Q IG+LD
Sbjct: 404 GRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALDRTKRQGAS----FIGILD 459
Query: 438 IFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEF-TDNQDAL 496
I GFE F +NSFEQLCIN+ NE LQQ F +F LEQEEY E I+W I+F D Q +
Sbjct: 460 IAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCI 519
Query: 497 DMIAN--KPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKN-NHETQFGINH 553
D+I P +++L+DEE FPK TD T + KL + ++ + P+ + F I H
Sbjct: 520 DLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIH 579
Query: 554 FAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQ--------------ADVAM 599
+AG V Y+ +L KN D L+ ++ L+H S ++F+ ++++ + A
Sbjct: 580 YAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAELWKDVDRIVGLDQVTGMTETAF 639
Query: 600 GAETRKRS---PTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQL 656
G+ + + T+ +K SL LM TL P FVRCI PN K+ D HL + QL
Sbjct: 640 GSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQL 699
Query: 657 RYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTH 716
R +G++E IRI R G+P R F EF +RY +L P P D + C+RM A+
Sbjct: 700 RCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKGFM-DGKQACERMIRALELDP 758
Query: 717 DDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLK---NAATL 773
+ ++IG++KIF + LE ERD ITD +I Q V RG+ R F K + +A +
Sbjct: 759 NLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKV 818
Query: 774 IQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAF 833
+QR+ + +++ R+ F +++ L + + ++ + + +++ + +
Sbjct: 819 LQRNCAAYLKLRHWQWWRV-FTKVKPLLQVTRQEEELQAKDEELLKVKEK---------- 867
Query: 834 RHRLWAVLTVQAYARGMI--ARRLHQRLRAE---YLWRLEAEKMRLAEEEKLRKEMSAKK 888
Q G + R HQ+L E +L+AE AE E++R ++AKK
Sbjct: 868 ----------QTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKK 917
Query: 889 -------------AKEEAER----KHQERLAQLAREDAERELKEKEAARRKKELLEQMER 931
+EE ER +++++ Q +D E +L E+E AR+K +L +
Sbjct: 918 QELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAE 977
Query: 932 ARHEPVNHSDMV--DKMFGFLGTSGGLPGQEGQAPSGFEDLE---------RGRREMVEE 980
A+ + + ++ D+ F+ + + + S + E R ++E++
Sbjct: 978 AKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMIS 1037
Query: 981 DLDAALPLPDEDEEDLSEYKFAKFAATYFQGTTTHSYTRRPLKQPLLYHDDEGDQLAALA 1040
DL+ L ++ ++L + A G TT D DQ+A L
Sbjct: 1038 DLEERLKKEEKTRQELEK------AKRKLDGETT----------------DLQDQIAELQ 1075
Query: 1041 VWITILRFMGDLPEPKYHTAMSDGSEKIPVMTKIYETLGKKTYKRELQALQGEGEAQLPE 1100
I L+ E + A++ G + ETL K + ++ LQ AQ+ E
Sbjct: 1076 AQIDELKLQLAKKEEELQGALARGDD---------ETLHKNNALKVVRELQ----AQIAE 1122
Query: 1101 GQKKSSVRHKLVHLTLKKKSKLTEEVTKRLHDGESTVQGNSMLEDRPTSNLEKL 1154
Q+ + K+K L+EE+ + E T+ + ++ T +++
Sbjct: 1123 LQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEV 1176
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 497 bits (1280), Expect = e-140
Identities = 344/949 (36%), Positives = 512/949 (53%), Gaps = 86/949 (9%)
Query: 27 VVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNLL 86
VV+L ++G+ V +D I+ M+P VEDM L LNEA +L NL
Sbjct: 59 VVELVENGKKVTVGKDD------------IQKMNPPKFSKVEDMAELTCLNEASVLHNLR 106
Query: 87 IRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMK 146
RY LIYTY+G V VNPY+ L IYS + + Y KK EMPPHI+AIAD Y +M
Sbjct: 107 ERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSML 166
Query: 147 RNSRDQCCIISGESGAGKTESTKLILQFLAAISGQHSW---------IEQQVLEATPILE 197
++ DQ + +GESGAGKTE+TK ++Q+LA ++ H +E+Q+L+A PILE
Sbjct: 167 QDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEKQLLQANPILE 226
Query: 198 AFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYC 257
AFGNAKT++NDNSSRFGK+I I+F+ G I GA IE YLLEKSR RQA DER +H+FY
Sbjct: 227 AFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYY 286
Query: 258 MLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTENWE 317
M+ G E + L L ++Y +L+ G + D + + AM ++ F++ E
Sbjct: 287 MIAGAKEKMRSDLLLEGFNNYTFLSNG-FVPIPAAQDDEMFQETVEAMAIMGFSEEEQLS 345
Query: 318 ISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPDL-MSCLTSRTLI 376
I K+++++L LGN+ ++ N D + + + L+ +N D S LT R +
Sbjct: 346 ILKVVSSVLQLGNIVFKKE--RNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKV 403
Query: 377 TRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRSIGLL 436
R + V ++EQA +A K Y RLF WI+ ++N A+ K Q +G+L
Sbjct: 404 GR-DVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGAS----FLGIL 458
Query: 437 DIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEF-TDNQDA 495
DI GFE F VNSFEQLCIN+ NE LQQ F +F LEQEEY E I+W I+F D Q
Sbjct: 459 DIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPC 518
Query: 496 LDMI--ANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKN-NHETQFGIN 552
+++I N P +++L+DEE FPK TD + + KL ++ + + PK +T+F I
Sbjct: 519 IELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSII 578
Query: 553 HFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIF----------------QAD 596
H+AG V Y +L KN D L+ ++ L+++S +KF+ ++ ++
Sbjct: 579 HYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESS 638
Query: 597 VAMGAETRK-RSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQ 655
+ ++T+K T+ +K L LM TL P FVRCI PN K+ D L + Q
Sbjct: 639 LPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQ 698
Query: 656 LRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGT 715
LR +G++E IRI R G+P R F EF +RY +L P D + C M +A+
Sbjct: 699 LRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFM-DGKQACILMIKALELD 757
Query: 716 HDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAAT--- 772
+ ++IG++KIF + LE ERD ITD ++ Q + RG+ R F K + T
Sbjct: 758 PNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMK 817
Query: 773 LIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLAR---QRIIQFQARCRAYLV 829
+IQR+ + +N+ RL F +++ L + + ++ + Q+ + Q + L
Sbjct: 818 VIQRNCAAYLKLRNWQWWRL-FTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELK 876
Query: 830 RKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRL------AEEEKLRKE 883
+H + LT + L ++L+AE EAE+MR+ E E++ E
Sbjct: 877 ELEQKH---SQLTEE-------KNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHE 926
Query: 884 MSAKKAKEE-------AERKHQERLAQLAREDAERELKEKEAARRKKEL 925
M A+ +EE AERK ++AQ D E +L+E+EAAR+K +L
Sbjct: 927 MEARLEEEEDRGQQLQAERK---KMAQ-QMLDLEEQLEEEEAARQKLQL 971
Score = 52.0 bits (123), Expect = 6e-06
Identities = 37/114 (32%), Positives = 55/114 (48%), Gaps = 6/114 (5%)
Query: 817 IIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAE 876
I+ FQA CR YL RKAF R + ++ R A + +LR WRL + L +
Sbjct: 790 IMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAA---YLKLRNWQWWRLFTKVKPLLQ 846
Query: 877 EEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQME 930
+ +EM +AKE+ +K +ER + E E E K + K L EQ++
Sbjct: 847 VTRQEEEM---QAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQ 897
Score = 35.4 bits (80), Expect = 0.61
Identities = 59/266 (22%), Positives = 108/266 (40%), Gaps = 35/266 (13%)
Query: 871 KMRLAEEEKLRKEMSAKKAKEEAERK-HQERLAQLAREDAERELKEKEAARRKKELLEQM 929
++RL +EEK R+E+ K K E + E++A L + AE ++ + A++++EL +
Sbjct: 1040 EVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM---QLAKKEEELQAAL 1096
Query: 930 ERARHEPVNHSDMVDKMFGFLGTSGGLPGQEGQAPSGFEDLERGRREMVEEDLDAALPLP 989
R E ++ + K+ G L + E+ +R++ EE L+A L
Sbjct: 1097 ARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEE-LEA---LK 1152
Query: 990 DEDEEDL-SEYKFAKFAATYFQGTTTHSYTRRPLKQPLLYHDDEGDQLAALAVWITILRF 1048
E E+ L S + A Q T ++ L + H+ + ++
Sbjct: 1153 TELEDTLDSTATQQELRAKREQEVTV---LKKALDEETRSHEAQVQEM------------ 1197
Query: 1049 MGDLPEPKYHTAMSDGSEKIPVMTKIYETLGKKTYKRELQALQGEGEAQLPEGQKKSSVR 1108
K+ A+ + +E++ + L K E + GE ++ GQ K V
Sbjct: 1198 -----RQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRV-LGQAKQEVE 1251
Query: 1109 HKLVHLTLKKKSKLTEEVTKRLHDGE 1134
HK KK +E+ + DGE
Sbjct: 1252 HK-----KKKLEAQVQELQSKCSDGE 1272
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 497 bits (1280), Expect = e-140
Identities = 344/949 (36%), Positives = 512/949 (53%), Gaps = 86/949 (9%)
Query: 27 VVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNLL 86
VV+L ++G+ V +D I+ M+P VEDM L LNEA +L NL
Sbjct: 59 VVELVENGKKVTVGKDD------------IQKMNPPKFSKVEDMAELTCLNEASVLHNLR 106
Query: 87 IRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMK 146
RY LIYTY+G V VNPY+ L IYS + + Y KK EMPPHI+AIAD Y +M
Sbjct: 107 ERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSML 166
Query: 147 RNSRDQCCIISGESGAGKTESTKLILQFLAAISGQHSW---------IEQQVLEATPILE 197
++ DQ + +GESGAGKTE+TK ++Q+LA ++ H +E+Q+L+A PILE
Sbjct: 167 QDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEKQLLQANPILE 226
Query: 198 AFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYC 257
AFGNAKT++NDNSSRFGK+I I+F+ G I GA IE YLLEKSR RQA DER +H+FY
Sbjct: 227 AFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYY 286
Query: 258 MLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTENWE 317
M+ G E + L L ++Y +L+ G + D + + AM ++ F++ E
Sbjct: 287 MIAGAKEKMRSDLLLEGFNNYTFLSNG-FVPIPAAQDDEMFQETVEAMAIMGFSEEEQLS 345
Query: 318 ISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPDL-MSCLTSRTLI 376
I K+++++L LGN+ ++ N D + + + L+ +N D S LT R +
Sbjct: 346 ILKVVSSVLQLGNIVFKKE--RNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKV 403
Query: 377 TRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRSIGLL 436
R + V ++EQA +A K Y RLF WI+ ++N A+ K Q +G+L
Sbjct: 404 GR-DVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGAS----FLGIL 458
Query: 437 DIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEF-TDNQDA 495
DI GFE F VNSFEQLCIN+ NE LQQ F +F LEQEEY E I+W I+F D Q
Sbjct: 459 DIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPC 518
Query: 496 LDMI--ANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKN-NHETQFGIN 552
+++I N P +++L+DEE FPK TD + + KL ++ + + PK +T+F I
Sbjct: 519 IELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSII 578
Query: 553 HFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIF----------------QAD 596
H+AG V Y +L KN D L+ ++ L+++S +KF+ ++ ++
Sbjct: 579 HYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESS 638
Query: 597 VAMGAETRK-RSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQ 655
+ ++T+K T+ +K L LM TL P FVRCI PN K+ D L + Q
Sbjct: 639 LPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQ 698
Query: 656 LRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGT 715
LR +G++E IRI R G+P R F EF +RY +L P D + C M +A+
Sbjct: 699 LRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFM-DGKQACILMIKALELD 757
Query: 716 HDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAAT--- 772
+ ++IG++KIF + LE ERD ITD ++ Q + RG+ R F K + T
Sbjct: 758 PNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMK 817
Query: 773 LIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLAR---QRIIQFQARCRAYLV 829
+IQR+ + +N+ RL F +++ L + + ++ + Q+ + Q + L
Sbjct: 818 VIQRNCAAYLKLRNWQWWRL-FTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELK 876
Query: 830 RKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRL------AEEEKLRKE 883
+H + LT + L ++L+AE EAE+MR+ E E++ E
Sbjct: 877 ELEQKH---SQLTEE-------KNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHE 926
Query: 884 MSAKKAKEE-------AERKHQERLAQLAREDAERELKEKEAARRKKEL 925
M A+ +EE AERK ++AQ D E +L+E+EAAR+K +L
Sbjct: 927 MEARLEEEEDRGQQLQAERK---KMAQ-QMLDLEEQLEEEEAARQKLQL 971
Score = 52.0 bits (123), Expect = 6e-06
Identities = 37/114 (32%), Positives = 55/114 (48%), Gaps = 6/114 (5%)
Query: 817 IIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAE 876
I+ FQA CR YL RKAF R + ++ R A + +LR WRL + L +
Sbjct: 790 IMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAA---YLKLRNWQWWRLFTKVKPLLQ 846
Query: 877 EEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQME 930
+ +EM +AKE+ +K +ER + E E E K + K L EQ++
Sbjct: 847 VTRQEEEM---QAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQ 897
Score = 35.4 bits (80), Expect = 0.61
Identities = 59/266 (22%), Positives = 108/266 (40%), Gaps = 35/266 (13%)
Query: 871 KMRLAEEEKLRKEMSAKKAKEEAERK-HQERLAQLAREDAERELKEKEAARRKKELLEQM 929
++RL +EEK R+E+ K K E + E++A L + AE ++ + A++++EL +
Sbjct: 1040 EVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM---QLAKKEEELQAAL 1096
Query: 930 ERARHEPVNHSDMVDKMFGFLGTSGGLPGQEGQAPSGFEDLERGRREMVEEDLDAALPLP 989
R E ++ + K+ G L + E+ +R++ EE L+A L
Sbjct: 1097 ARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEE-LEA---LK 1152
Query: 990 DEDEEDL-SEYKFAKFAATYFQGTTTHSYTRRPLKQPLLYHDDEGDQLAALAVWITILRF 1048
E E+ L S + A Q T ++ L + H+ + ++
Sbjct: 1153 TELEDTLDSTATQQELRAKREQEVTV---LKKALDEETRSHEAQVQEM------------ 1197
Query: 1049 MGDLPEPKYHTAMSDGSEKIPVMTKIYETLGKKTYKRELQALQGEGEAQLPEGQKKSSVR 1108
K+ A+ + +E++ + L K E + GE ++ GQ K V
Sbjct: 1198 -----RQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRV-LGQAKQEVE 1251
Query: 1109 HKLVHLTLKKKSKLTEEVTKRLHDGE 1134
HK KK +E+ + DGE
Sbjct: 1252 HK-----KKKLEAQVQELQSKCSDGE 1272
>gi|134288915 myosin IIIB isoform 1 [Homo sapiens]
Length = 1314
Score = 495 bits (1274), Expect = e-139
Identities = 294/785 (37%), Positives = 436/785 (55%), Gaps = 62/785 (7%)
Query: 37 QVVDDEDNEHWISPQNATHIKPMHPTSVHGVE------DMIRLGDLNEAGILRNLLIRYR 90
+V+ D+ +++ ++ + P V E D++ L L+E I+ L RY
Sbjct: 309 KVLQDQKHQNPVAKTRHERMHTRRPYHVEDAEKYCLEDDLVNLEVLDEDTIIHQLQKRYA 368
Query: 91 DHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSR 150
D LIYTY G IL+A+NP+Q LSIYSP+ R Y K PPHIFA AD Y M S+
Sbjct: 369 DLLIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKRASNPPHIFASADAAYQCMVTLSK 428
Query: 151 DQCCIISGESGAGKTESTKLILQFLAAIS-GQHSWIEQQVLEATPILEAFGNAKTIRNDN 209
DQC +ISGESG+GKTES LI+Q L + + + +++L+ ++EAFGN+ T NDN
Sbjct: 429 DQCIVISGESGSGKTESAHLIVQHLTFLGKANNQTLREKILQVNSLVEAFGNSCTAINDN 488
Query: 210 SSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQK-K 268
SSRFGKY+++ F G + GA+I +YLLEKSRV +QA E+N+H+FY + G+ +K
Sbjct: 489 SSRFGKYLEMMFTPTGVVMGARISEYLLEKSRVIKQAAREKNFHIFYYIYAGLHHQKKLS 548
Query: 269 KLGLGQASDYNYLAMGNCITCEGRVDSQEYAN----IRSAMKVLMFTDTENWEISKLLAA 324
L + Y+A + Y I+ +++ FTD E + ++LA
Sbjct: 549 DFRLPEEKPPRYIADETGRVMHDITSKESYRRQFEAIQHCFRIIGFTDKEVHSVYRILAG 608
Query: 325 ILHLGNLQYEARTFEN-LDACEVLFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVS 383
IL++GN+++ A + ++ D EV + +L AAS+L ++P +L LTS ++TRGET+
Sbjct: 609 ILNIGNIEFAAISSQHQTDKSEVPNAEALQNAASVLCISPEELQEALTSHCVVTRGETII 668
Query: 384 TPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRSIGLLDIFGFEN 443
+ ++A DVRDA K +YGRLF WIV++IN + + ++G+LDIFGFEN
Sbjct: 669 RANTVDRAADVRDAMSKALYGRLFSWIVNRINTLLQPDENICSAGGGMNVGILDIFGFEN 728
Query: 444 FAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKP 503
F NSFEQLCIN ANE +Q +F +HVF LEQ EY E ID + +E+ DN+ LDM KP
Sbjct: 729 FQRNSFEQLCINIANEQIQYYFNQHVFALEQMEYQNEGIDAVPVEYEDNRPLLDMFLQKP 788
Query: 504 MNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKNNHETQFGINHFAGIVYYETQ 563
+ +++L+DEES+FP+ TD T++ K + L Y E FGI H+AG V Y+
Sbjct: 789 LGLLALLDEESRFPQATDQTLVDKF--EDNLRCKYFWRPKGVELCFGIQHYAGKVLYDAS 846
Query: 564 GFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQADVAMG---AETRKR-------------- 606
G LEKNRDTL D++ ++ +S N ++Q+F + A+TR R
Sbjct: 847 GVLEKNRDTLPADVVVVLRTSENMLLQQLFSIPLTKTGNLAQTRARITVASSSLPPHFSA 906
Query: 607 ---------------------SPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPM 645
T++S F+ SL L+ + QP FVRCIKPN+ ++ +
Sbjct: 907 GKAKVDTLEVIRHPEETTNMKRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREAL 966
Query: 646 LFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTC 705
F R + QLR +G++ET+ IRR GY R F EFV+RY L A+
Sbjct: 967 QFSRERVLAQLRSTGILETVSIRRQGYSHRILFEEFVKRYYYL------AFTAHQTPLAS 1020
Query: 706 QRMAEAVL--GTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSN 763
+ A+L D W +GKTK+FLK +H L + + + RV++LQ +G+
Sbjct: 1021 KESCVAILEKSRLDHWVLGKTKVFLKYYHVEQLNLLL-REVIGRVVVLQAYTKGWLGARR 1079
Query: 764 FLKLK 768
+ K++
Sbjct: 1080 YKKVR 1084
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 494 bits (1273), Expect = e-139
Identities = 344/956 (35%), Positives = 512/956 (53%), Gaps = 93/956 (9%)
Query: 27 VVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNLL 86
VV+L ++G+ V +D I+ M+P VEDM L LNEA +L NL
Sbjct: 59 VVELVENGKKVTVGKDD------------IQKMNPPKFSKVEDMAELTCLNEASVLHNLR 106
Query: 87 IRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMK 146
RY LIYTY+G V VNPY+ L IYS + + Y KK EMPPHI+AIAD Y +M
Sbjct: 107 ERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSML 166
Query: 147 RNSRDQCCIISGESGAGKTESTKLILQFLAAISGQHSW----------------IEQQVL 190
++ DQ + +GESGAGKTE+TK ++Q+LA ++ H +E+Q+L
Sbjct: 167 QDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITQGPSFAYGELEKQLL 226
Query: 191 EATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDER 250
+A PILEAFGNAKT++NDNSSRFGK+I I+F+ G I GA IE YLLEKSR RQA DER
Sbjct: 227 QANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDER 286
Query: 251 NYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSAMKVLMF 310
+H+FY M+ G E + L L ++Y +L+ G + D + + AM ++ F
Sbjct: 287 TFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNG-FVPIPAAQDDEMFQETVEAMAIMGF 345
Query: 311 TDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPDL-MSC 369
++ E I K+++++L LGN+ ++ N D + + + L+ +N D S
Sbjct: 346 SEEEQLSILKVVSSVLQLGNIVFKKE--RNTDQASMPDNTAAQKVCHLMGINVTDFTRSI 403
Query: 370 LTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNS 429
LT R + R + V ++EQA +A K Y RLF WI+ ++N A+ K Q
Sbjct: 404 LTPRIKVGR-DVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGAS-- 460
Query: 430 RRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEF 489
+G+LDI GFE F VNSFEQLCIN+ NE LQQ F +F LEQEEY E I+W I+F
Sbjct: 461 --FLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDF 518
Query: 490 -TDNQDALDMI--ANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKN-NH 545
D Q +++I N P +++L+DEE FPK TD + + KL ++ + + PK
Sbjct: 519 GLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKD 578
Query: 546 ETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIF------------ 593
+T+F I H+AG V Y +L KN D L+ ++ L+++S +KF+ ++
Sbjct: 579 KTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQM 638
Query: 594 ----QADVAMGAETRK-RSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFD 648
++ + ++T+K T+ +K L LM TL P FVRCI PN K+ D
Sbjct: 639 AKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLD 698
Query: 649 RHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRM 708
L + QLR +G++E IRI R G+P R F EF +RY +L P D + C M
Sbjct: 699 AFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFM-DGKQACILM 757
Query: 709 AEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLK 768
+A+ + ++IG++KIF + LE ERD ITD ++ Q + RG+ R F K +
Sbjct: 758 IKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQ 817
Query: 769 NAAT---LIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLAR---QRIIQFQA 822
T +IQR+ + +N+ RL F +++ L + + ++ + Q+ + Q
Sbjct: 818 QQLTAMKVIQRNCAAYLKLRNWQWWRL-FTKVKPLLQVTRQEEEMQAKEDELQKTKERQQ 876
Query: 823 RCRAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRL------AE 876
+ L +H + LT + L ++L+AE EAE+MR+ E
Sbjct: 877 KAENELKELEQKH---SQLTEE-------KNLLQEQLQAETELYAEAEEMRVRLAAKKQE 926
Query: 877 EEKLRKEMSAKKAKEE-------AERKHQERLAQLAREDAERELKEKEAARRKKEL 925
E++ EM A+ +EE AERK ++AQ D E +L+E+EAAR+K +L
Sbjct: 927 LEEILHEMEARLEEEEDRGQQLQAERK---KMAQ-QMLDLEEQLEEEEAARQKLQL 978
Score = 52.0 bits (123), Expect = 6e-06
Identities = 37/114 (32%), Positives = 55/114 (48%), Gaps = 6/114 (5%)
Query: 817 IIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAE 876
I+ FQA CR YL RKAF R + ++ R A + +LR WRL + L +
Sbjct: 797 IMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAA---YLKLRNWQWWRLFTKVKPLLQ 853
Query: 877 EEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQME 930
+ +EM +AKE+ +K +ER + E E E K + K L EQ++
Sbjct: 854 VTRQEEEM---QAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQ 904
Score = 35.4 bits (80), Expect = 0.61
Identities = 59/266 (22%), Positives = 108/266 (40%), Gaps = 35/266 (13%)
Query: 871 KMRLAEEEKLRKEMSAKKAKEEAERK-HQERLAQLAREDAERELKEKEAARRKKELLEQM 929
++RL +EEK R+E+ K K E + E++A L + AE ++ + A++++EL +
Sbjct: 1047 EVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM---QLAKKEEELQAAL 1103
Query: 930 ERARHEPVNHSDMVDKMFGFLGTSGGLPGQEGQAPSGFEDLERGRREMVEEDLDAALPLP 989
R E ++ + K+ G L + E+ +R++ EE L+A L
Sbjct: 1104 ARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEE-LEA---LK 1159
Query: 990 DEDEEDL-SEYKFAKFAATYFQGTTTHSYTRRPLKQPLLYHDDEGDQLAALAVWITILRF 1048
E E+ L S + A Q T ++ L + H+ + ++
Sbjct: 1160 TELEDTLDSTATQQELRAKREQEVTV---LKKALDEETRSHEAQVQEM------------ 1204
Query: 1049 MGDLPEPKYHTAMSDGSEKIPVMTKIYETLGKKTYKRELQALQGEGEAQLPEGQKKSSVR 1108
K+ A+ + +E++ + L K E + GE ++ GQ K V
Sbjct: 1205 -----RQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRV-LGQAKQEVE 1258
Query: 1109 HKLVHLTLKKKSKLTEEVTKRLHDGE 1134
HK KK +E+ + DGE
Sbjct: 1259 HK-----KKKLEAQVQELQSKCSDGE 1279
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 494 bits (1273), Expect = e-139
Identities = 344/956 (35%), Positives = 512/956 (53%), Gaps = 93/956 (9%)
Query: 27 VVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNLL 86
VV+L ++G+ V +D I+ M+P VEDM L LNEA +L NL
Sbjct: 59 VVELVENGKKVTVGKDD------------IQKMNPPKFSKVEDMAELTCLNEASVLHNLR 106
Query: 87 IRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMK 146
RY LIYTY+G V VNPY+ L IYS + + Y KK EMPPHI+AIAD Y +M
Sbjct: 107 ERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSML 166
Query: 147 RNSRDQCCIISGESGAGKTESTKLILQFLAAISGQHSW----------------IEQQVL 190
++ DQ + +GESGAGKTE+TK ++Q+LA ++ H +E+Q+L
Sbjct: 167 QDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITQGPSFAYGELEKQLL 226
Query: 191 EATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDER 250
+A PILEAFGNAKT++NDNSSRFGK+I I+F+ G I GA IE YLLEKSR RQA DER
Sbjct: 227 QANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDER 286
Query: 251 NYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSAMKVLMF 310
+H+FY M+ G E + L L ++Y +L+ G + D + + AM ++ F
Sbjct: 287 TFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNG-FVPIPAAQDDEMFQETVEAMAIMGF 345
Query: 311 TDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPDL-MSC 369
++ E I K+++++L LGN+ ++ N D + + + L+ +N D S
Sbjct: 346 SEEEQLSILKVVSSVLQLGNIVFKKE--RNTDQASMPDNTAAQKVCHLMGINVTDFTRSI 403
Query: 370 LTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNS 429
LT R + R + V ++EQA +A K Y RLF WI+ ++N A+ K Q
Sbjct: 404 LTPRIKVGR-DVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGAS-- 460
Query: 430 RRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEF 489
+G+LDI GFE F VNSFEQLCIN+ NE LQQ F +F LEQEEY E I+W I+F
Sbjct: 461 --FLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDF 518
Query: 490 -TDNQDALDMI--ANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKN-NH 545
D Q +++I N P +++L+DEE FPK TD + + KL ++ + + PK
Sbjct: 519 GLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKD 578
Query: 546 ETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIF------------ 593
+T+F I H+AG V Y +L KN D L+ ++ L+++S +KF+ ++
Sbjct: 579 KTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQM 638
Query: 594 ----QADVAMGAETRK-RSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFD 648
++ + ++T+K T+ +K L LM TL P FVRCI PN K+ D
Sbjct: 639 AKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLD 698
Query: 649 RHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRM 708
L + QLR +G++E IRI R G+P R F EF +RY +L P D + C M
Sbjct: 699 AFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFM-DGKQACILM 757
Query: 709 AEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLK 768
+A+ + ++IG++KIF + LE ERD ITD ++ Q + RG+ R F K +
Sbjct: 758 IKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQ 817
Query: 769 NAAT---LIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLAR---QRIIQFQA 822
T +IQR+ + +N+ RL F +++ L + + ++ + Q+ + Q
Sbjct: 818 QQLTAMKVIQRNCAAYLKLRNWQWWRL-FTKVKPLLQVTRQEEEMQAKEDELQKTKERQQ 876
Query: 823 RCRAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRL------AE 876
+ L +H + LT + L ++L+AE EAE+MR+ E
Sbjct: 877 KAENELKELEQKH---SQLTEE-------KNLLQEQLQAETELYAEAEEMRVRLAAKKQE 926
Query: 877 EEKLRKEMSAKKAKEE-------AERKHQERLAQLAREDAERELKEKEAARRKKEL 925
E++ EM A+ +EE AERK ++AQ D E +L+E+EAAR+K +L
Sbjct: 927 LEEILHEMEARLEEEEDRGQQLQAERK---KMAQ-QMLDLEEQLEEEEAARQKLQL 978
Score = 52.0 bits (123), Expect = 6e-06
Identities = 37/114 (32%), Positives = 55/114 (48%), Gaps = 6/114 (5%)
Query: 817 IIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAE 876
I+ FQA CR YL RKAF R + ++ R A + +LR WRL + L +
Sbjct: 797 IMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAA---YLKLRNWQWWRLFTKVKPLLQ 853
Query: 877 EEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQME 930
+ +EM +AKE+ +K +ER + E E E K + K L EQ++
Sbjct: 854 VTRQEEEM---QAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQ 904
Score = 35.4 bits (80), Expect = 0.61
Identities = 59/266 (22%), Positives = 108/266 (40%), Gaps = 35/266 (13%)
Query: 871 KMRLAEEEKLRKEMSAKKAKEEAERK-HQERLAQLAREDAERELKEKEAARRKKELLEQM 929
++RL +EEK R+E+ K K E + E++A L + AE ++ + A++++EL +
Sbjct: 1047 EVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM---QLAKKEEELQAAL 1103
Query: 930 ERARHEPVNHSDMVDKMFGFLGTSGGLPGQEGQAPSGFEDLERGRREMVEEDLDAALPLP 989
R E ++ + K+ G L + E+ +R++ EE L+A L
Sbjct: 1104 ARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEE-LEA---LK 1159
Query: 990 DEDEEDL-SEYKFAKFAATYFQGTTTHSYTRRPLKQPLLYHDDEGDQLAALAVWITILRF 1048
E E+ L S + A Q T ++ L + H+ + ++
Sbjct: 1160 TELEDTLDSTATQQELRAKREQEVTV---LKKALDEETRSHEAQVQEM------------ 1204
Query: 1049 MGDLPEPKYHTAMSDGSEKIPVMTKIYETLGKKTYKRELQALQGEGEAQLPEGQKKSSVR 1108
K+ A+ + +E++ + L K E + GE ++ GQ K V
Sbjct: 1205 -----RQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRV-LGQAKQEVE 1258
Query: 1109 HKLVHLTLKKKSKLTEEVTKRLHDGE 1134
HK KK +E+ + DGE
Sbjct: 1259 HK-----KKKLEAQVQELQSKCSDGE 1279
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 493 bits (1269), Expect = e-139
Identities = 333/963 (34%), Positives = 507/963 (52%), Gaps = 65/963 (6%)
Query: 19 EFDVPIGAVVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNE 78
E D + A VK +G V+ +D + + ++PM+P +EDM + LNE
Sbjct: 82 EQDAYVEAEVKSEATGGRVTVETKDQK--VLMVREAELQPMNPPRFDLLEDMAMMTHLNE 139
Query: 79 AGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIA 138
A +L NL RY +IYTY+G V +NPY+ L +Y+ + Y K+ + PPHI+A+A
Sbjct: 140 ASVLHNLRQRYARWMIYTYSGLFCVTINPYKWLPVYTASVVAAYKGKRRSDSPPHIYAVA 199
Query: 139 DNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISG---------------QHS 183
DN Y +M RN +Q +I+GESGAGKT +TK ++Q+ A ++
Sbjct: 200 DNAYNDMLRNRDNQSMLITGESGAGKTVNTKRVIQYFAIVAALGDGPGKKAQFLATKTGG 259
Query: 184 WIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVC 243
+E Q++EA P +EAFGNAKT+RNDNSSRFGK+I IHF G + A I+ YLLEKSRV
Sbjct: 260 TLEDQIIEANPAMEAFGNAKTLRNDNSSRFGKFIRIHFGPSGKLASADIDSYLLEKSRVI 319
Query: 244 RQALDERNYHVFYCMLEGMSEDQKKKLGLG-QASDYNYLAMGNCITCEGRVDSQEYANIR 302
Q ER+YHV+Y +L G + + L L DY++ + G IT + D +E
Sbjct: 320 FQLPGERSYHVYYQILSGRKPELQDMLLLSMNPYDYHFCSQG-VITVDNMNDGEELIATD 378
Query: 303 SAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVN 362
AM +L F+ E K++ A+LH GN++++ + E + E + S AA L+ V+
Sbjct: 379 HAMDILGFSVDEKCACYKIVGALLHFGNMKFKQKQRE--EQAEADGTESADKAAYLMGVS 436
Query: 363 PPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPP 422
DL+ L + E V+ S EQ + A K Y RLF W+V +IN +
Sbjct: 437 SGDLLKGLLHPRVRVGNEYVTKGQSVEQVVFAVGALAKATYDRLFRWLVSRINQTL---- 492
Query: 423 SQDVKNSRR-SIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLES 481
D K R+ IG+LDI GFE F NSFEQLCINF NE LQQFF +H+F LEQEEY E
Sbjct: 493 --DTKLPRQFFIGVLDIAGFEIFEFNSFEQLCINFTNEKLQQFFNQHMFVLEQEEYKREG 550
Query: 482 IDWLHIEF-TDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHK-LNANYI 539
IDW+ I+F D Q +D+I KP+ I+S+++EE FPK +D + KL H + N+
Sbjct: 551 IDWVFIDFGLDLQPCIDLI-EKPLGILSILEEECMFPKASDASFRAKLYDNHAGKSPNFQ 609
Query: 540 PP----KNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQA 595
P K ++ F + H+AG+V Y G+LEKN+D L+ ++ + S+N+ + +++
Sbjct: 610 QPRPDKKRKYQAHFEVVHYAGVVPYSIVGWLEKNKDPLNETVVPIFQKSQNRLLATLYEN 669
Query: 596 DVAMGA---------ETRKRS---PTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKK 643
+ E RK++ T+S K +L LM L A QP FVRCI PNE K
Sbjct: 670 YAGSCSTEPPKSGVKEKRKKAASFQTVSQLHKENLNKLMTNLRATQPHFVRCIVPNENKT 729
Query: 644 PMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRG 703
P + D L + QLR +G++E IRI R G+P R + +F +RYR+L P P D R
Sbjct: 730 PGVMDAFLVLHQLRCNGVLEGIRICRQGFPNRLLYTDFRQRYRILNPSAIPDDTFMDSRK 789
Query: 704 TCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSN 763
+++ ++ H +Q G TK+F K +LE RD+ + + LLQ RG R
Sbjct: 790 ATEKLLGSLDLDHTQYQFGHTKVFFKAGLLGVLEELRDQRLAKVLTLLQARSRGRLMRLE 849
Query: 764 FLKL---KNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQF 820
+ +L ++A IQ + R N KN+ M+L F +++ L RS + ++ R +
Sbjct: 850 YQRLLGGRDALFTIQWNIRAFNAVKNWSWMKL-FFKMKPLLRSAQAEEELAALRAELRGL 908
Query: 821 QARCRAYLVRKAFRHRLWAVLT---------VQAYARGM--IARRLHQRLRAEYLWRLEA 869
+ A ++ +T +QA + R H ++++ +
Sbjct: 909 RGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCHLLIKSKVQLEGKV 968
Query: 870 EKM--RLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEKEAARRK-KELL 926
+++ RL +EE++ +++A++ K E E ++ + + KEK+A K K L
Sbjct: 969 KELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAEKEKQATENKVKNLT 1028
Query: 927 EQM 929
E+M
Sbjct: 1029 EEM 1031
Score = 33.1 bits (74), Expect = 3.1
Identities = 25/67 (37%), Positives = 38/67 (56%), Gaps = 6/67 (8%)
Query: 866 RLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEKEAARRKKEL 925
R+E E++ A+ +K KE+ A +A+E E ER A+ A E + EAAR +EL
Sbjct: 1142 RVEDEQLLGAQMQKKIKELQA-RAEELEEELEAERAAR-----ARVEKQRAEAARELEEL 1195
Query: 926 LEQMERA 932
E++E A
Sbjct: 1196 SERLEEA 1202
Score = 32.3 bits (72), Expect = 5.2
Identities = 29/110 (26%), Positives = 50/110 (45%), Gaps = 15/110 (13%)
Query: 852 ARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAE----RKHQERLAQLARE 907
A + + L+ E E+M+ E+ +R+ + + E+A +K ++L RE
Sbjct: 1811 AAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRE 1870
Query: 908 -DAERELKEKEAA----------RRKKELLEQMERARHEPVNHSDMVDKM 946
+AE + ++K+ A RR KEL Q E R D+VDK+
Sbjct: 1871 LEAELDAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLARMQDLVDKL 1920
Score = 32.0 bits (71), Expect = 6.8
Identities = 36/144 (25%), Positives = 59/144 (40%), Gaps = 33/144 (22%)
Query: 867 LEAEKMRLAEEEK-----LRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEKEAARR 921
LE K+RL E + L + SA A ++ +R H ER + R E +E EAA+R
Sbjct: 1463 LEKAKLRLQTESEDVTLELERATSAAAALDKKQR-HLERALEERRRQEEEMQRELEAAQR 1521
Query: 922 K---------------KELLEQMERARHEPVNHSDMVDKMFGFLGTSG-----------G 955
+ +E LE +E + E N + + + + SG
Sbjct: 1522 ESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKA 1581
Query: 956 LPGQEGQAPSGFEDLERGRREMVE 979
L G++ + + E+ E G E+ E
Sbjct: 1582 LEGEKSEIQAALEEAE-GALELEE 1604
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 490 bits (1262), Expect = e-138
Identities = 344/1029 (33%), Positives = 520/1029 (50%), Gaps = 88/1029 (8%)
Query: 28 VKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNLLI 87
+K G+V V +++ + P++ + M+P +EDM L LNE +L NL
Sbjct: 52 IKSSQDGKVTVETEDNRTLVVKPED---VYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKD 108
Query: 88 RYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMKR 147
RY +IYTY+G V VNPY+ L +Y+PE + Y KK E PPHIF+I+DN Y M
Sbjct: 109 RYTSWMIYTYSGLFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLT 168
Query: 148 NSRDQCCIISGESGAGKTESTKLILQFLAAI-----------SGQHSWIEQQVLEATPIL 196
+ +Q +I+GESGAGKT +TK ++Q+ A I S +E Q++ A P+L
Sbjct: 169 DRENQSILITGESGAGKTVNTKRVIQYFATIAATGDLAKKKDSKMKGTLEDQIISANPLL 228
Query: 197 EAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFY 256
EAFGNAKT+RNDNSSRFGK+I IHF G + A IE YLLEKSRV Q ER+YH+FY
Sbjct: 229 EAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFY 288
Query: 257 CMLEGMSEDQKKKLGL-GQASDYNYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTEN 315
+L + + L + DY +++ G I D++E SA+ +L FT E
Sbjct: 289 QILSNKKPELIELLLITTNPYDYPFISQGE-ILVASIDDAEELLATDSAIDILGFTPEEK 347
Query: 316 WEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPDLMSCLTSRTL 375
+ KL A++H GN++++ + E + E + A L+ +N DL+ L +
Sbjct: 348 SGLYKLTGAVMHYGNMKFKQKQRE--EQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRV 405
Query: 376 ITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRS-IG 434
E V+ + +Q +A K +Y +LF+W+V +IN + D K R+ IG
Sbjct: 406 KVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRINQQL------DTKLPRQHFIG 459
Query: 435 LLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEFTDNQD 494
+LDI GFE F NS EQLCINF NE LQQFF H+F LEQEEY E I+W I+F +
Sbjct: 460 VLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLA 519
Query: 495 ALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPP----KNNHETQFG 550
A + KPM I S+++EE FPK TDT+ +KL QH +N K E F
Sbjct: 520 ACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKPKVVKGRAEAHFS 579
Query: 551 INHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQADVAMGAETRKRS--- 607
+ H+AG V Y G+LEKN+D L+ ++ L S N+ + ++ A++ K+
Sbjct: 580 LIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAHLYATFATADADSGKKKVAK 639
Query: 608 ------PTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGM 661
T+S+ F+ +L LM L P FVRCI PNE K P + L + QLR +G+
Sbjct: 640 KKGSSFQTVSALFRENLNKLMSNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGV 699
Query: 662 METIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQI 721
+E IRI R G+P R + +F +RYRVL P + D + C+++ ++ H ++
Sbjct: 700 LEGIRICRKGFPNRILYGDFKQRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKF 759
Query: 722 GKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKL---KNAATLIQRHW 778
G TK+F K LE RD + + Q V RGF R F K+ + + IQ +
Sbjct: 760 GHTKVFFKAGLLGTLEEMRDDRLAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNI 819
Query: 779 RGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQAR-CRAYLVRKAFRHRL 837
R K++ M+L F +++ L +S + ++ ++ + + ++ RK +L
Sbjct: 820 RSFMNVKHWPWMKL-FFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKL 878
Query: 838 WAV--------LTVQAYARGMI--ARRLHQRLRAEYLWRLEAEKM--RLAEEEKLRKEMS 885
+ L VQA + ++ R Q ++A++ + +++ R +EE++ E++
Sbjct: 879 VTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELT 938
Query: 886 AKKAKEEAERKHQER--------LAQLAREDAERELKEK--------------EAARRKK 923
AKK K E E ++ LA++ +E E K K + R KK
Sbjct: 939 AKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKK 998
Query: 924 ELLEQMERARHEPVNHSDMVDKMFGFLGTSGGLPGQEGQAPSGFE-------DLERGRRE 976
L E ++A + D V+ + T L Q S E DLER +R+
Sbjct: 999 ALQEAHQQALDDLQAEEDKVNSL---NKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRK 1055
Query: 977 MVEEDLDAA 985
+ E DL A
Sbjct: 1056 L-EGDLKLA 1063
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 489 bits (1260), Expect = e-138
Identities = 326/945 (34%), Positives = 501/945 (53%), Gaps = 51/945 (5%)
Query: 24 IGAVVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILR 83
I A VK + +V+ D E ++ I+ M+P +EDM L LNEA +L
Sbjct: 64 IEAEVKGSEDDGTVIVETADGESLSIKEDK--IQQMNPPEFEMIEDMAMLTHLNEASVLH 121
Query: 84 NLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYF 143
L RY +IYTY+G V +NPY+ L +Y E + Y K+ E PPHIFA+A+N +
Sbjct: 122 TLKRRYGQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKRRSEAPPHIFAVANNAFQ 181
Query: 144 NMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISG------QHSWIEQQVLEATPILE 197
+M N +Q + +GESGAGKT ++K I+Q+ A I+ + +E Q+++A ILE
Sbjct: 182 DMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRKKQGALEDQIMQANTILE 241
Query: 198 AFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYC 257
AFGNAKT+RNDNSSRFGK+I +HF RG + I+ YLLEKSRV Q ERNYH+FY
Sbjct: 242 AFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIYLLEKSRVIFQQAGERNYHIFYQ 301
Query: 258 MLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTENWE 317
+L G E L SD+++ + G +T E D++E AM +L F E +
Sbjct: 302 ILSGQKELHDLLLVSANPSDFHFCSCG-AVTVESLDDAEELLATEQAMDILGFLPDEKYG 360
Query: 318 ISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPDLMSCLTSRTLIT 377
KL AI+H GN++++ + E + E + + AA L+ +N +L+ CL +
Sbjct: 361 CYKLTGAIMHFGNMKFKQKPRE--EQLEADGTENADKAAFLMGINSSELVKCLIHPRIKV 418
Query: 378 RGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRR-SIGLL 436
E V+ + EQ A K +Y R+F W+V +IN A+ D K SR+ IG+L
Sbjct: 419 GNEYVTRGQTIEQVTCAVGALSKSMYERMFKWLVARINRAL------DAKLSRQFFIGIL 472
Query: 437 DIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEF-TDNQDA 495
DI GFE NS EQLCINF NE LQQFF H+F LEQEEY ESI+W+ I F D Q
Sbjct: 473 DITGFEILEYNSLEQLCINFTNEKLQQFFNWHMFVLEQEEYKKESIEWVSIGFGLDLQAC 532
Query: 496 LDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYI----PPKNNHETQFGI 551
+D+I KPM I+S+++EE FPK TD T KL H + ++ P K E F +
Sbjct: 533 IDLI-EKPMGILSILEEECMFPKATDLTFKTKLFDNHFGKSVHLQKPKPDKKKFEAHFEL 591
Query: 552 NHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQ------ADVAMGAETRK 605
H+AG+V Y G+LEKN+D L+ ++ + S N+ + +F+ + + G + RK
Sbjct: 592 VHYAGVVPYNISGWLEKNKDLLNETVVAVFQKSSNRLLASLFENYMSTDSAIPFGEKKRK 651
Query: 606 RS---PTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMM 662
+ T++S K +L LM L + P FVRCI PN K P + D +L ++QLR +G++
Sbjct: 652 KGASFQTVASLHKENLNKLMTNLKSTAPHFVRCINPNVNKIPGILDPYLVLQQLRCNGVL 711
Query: 663 ETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIG 722
E RI R G+P R + +F +RY +L P P K R + + ++ H ++ G
Sbjct: 712 EGTRICREGFPNRLQYADFKQRYCILNPRTFPKSKFVSSRKAAEELLGSLEIDHTQYRFG 771
Query: 723 KTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKL---KNAATLIQRHWR 779
TK+F K LE RD+ ++ L Q +G R F K+ ++A LIQ + R
Sbjct: 772 ITKVFFKAGFLGQLEAIRDERLSKVFTLFQARAQGKLMRIKFQKILEERDALILIQWNIR 831
Query: 780 GHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQ-ARCRAYLVRKAFRHRLW 838
KN+ MRL F +++ L +S ++ ++ ++ Q Q A ++ R+ + +
Sbjct: 832 AFMAVKNWPWMRL-FFKIKPLVKSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQV 890
Query: 839 AV------LTVQAYARGMIARRLHQ------RLRAEYLWRLEAEKMRLAEEEKLRKEMSA 886
++ L +Q A + + + + + R++ R+ EEE++ E++A
Sbjct: 891 SLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTA 950
Query: 887 KKAKEEAE-RKHQERLAQLAREDAERELKEKEAARRKKELLEQME 930
+ K E E + ++ + L + E +++ + K L E++E
Sbjct: 951 RGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEEVE 995
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 483 bits (1243), Expect = e-136
Identities = 331/924 (35%), Positives = 495/924 (53%), Gaps = 67/924 (7%)
Query: 56 IKPMHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYS 115
+ +P +EDM L L+E +L NL RY +IYTY+G V VNPY+ L +Y+
Sbjct: 76 VMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYT 135
Query: 116 PEHIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFL 175
PE + Y KK E PPHIF+I+DN Y M + +Q +I+GESGAGKT +TK ++Q+
Sbjct: 136 PEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYF 195
Query: 176 AAIS--GQHS---------WIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKR 224
A I+ G S +E Q+++A P LEAFGNAKT+RNDNSSRFGK+I IHF
Sbjct: 196 AVIAAIGDRSKKDQSPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGAT 255
Query: 225 GAIEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGL-GQASDYNYLAM 283
G + A IE YLLEKSRV Q ER+YH+FY +L + L + DY +++
Sbjct: 256 GKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFISQ 315
Query: 284 GNCITCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDA 343
G T D++E +A VL FT E + KL AI+H GN++++ + E +
Sbjct: 316 GET-TVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQRE--EQ 372
Query: 344 CEVLFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIY 403
E + +A L+ +N DL+ L + E V+ + +Q + A K +Y
Sbjct: 373 AEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVY 432
Query: 404 GRLFVWIVDKINAAIYKPPSQDVKNSRRS-IGLLDIFGFENFAVNSFEQLCINFANEHLQ 462
R+F W+V +INA + + K R+ IG+LDI GFE F NSFEQLCINF NE LQ
Sbjct: 433 ERMFNWMVTRINATL------ETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQ 486
Query: 463 QFFVRHVFKLEQEEYDLESIDWLHIEF-TDNQDALDMIANKPMNIISLIDEESKFPKGTD 521
QFF H+F LEQEEY E I+W I+F D Q +D+I KPM I+S+++EE FPK TD
Sbjct: 487 QFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLI-EKPMGIMSILEEECMFPKATD 545
Query: 522 TTMLHKLNSQHK-LNANYIPPKN---NHETQFGINHFAGIVYYETQGFLEKNRDTLHGDI 577
T KL H +AN+ P+N E F + H+AGIV Y G+L+KN+D L+ +
Sbjct: 546 MTFKAKLFDNHLGKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETV 605
Query: 578 IQLVHSSRNKFIKQIF------QADVAMGAETRKRSP---TLSSQFKRSLELLMRTLGAC 628
+ L S K + +F A + G K+ T+S+ + +L LM L +
Sbjct: 606 VGLYQKSSLKLLSTLFANYAGADAPIEKGKGKAKKGSSFQTVSALHRENLNKLMTNLRST 665
Query: 629 QPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVL 688
P FVRCI PNE K P + D L + QLR +G++E IRI R G+P R + +F +RYR+L
Sbjct: 666 HPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRIL 725
Query: 689 LPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRV 748
P P + D R +++ ++ H+ ++ G TK+F K LLE RD+ ++ +
Sbjct: 726 NPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRII 785
Query: 749 ILLQKVIRGFKDRSNFLKL---KNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRK 805
+Q RG R + KL +++ +IQ + R KN+ M+L F +++ L +S +
Sbjct: 786 TRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYF-KIKPLLKSAE 844
Query: 806 LHQQYRLARQRIIQF-QARCRAYLVRKAFRHRLWAVLT--------VQAYARGMI--ARR 854
++ ++ + +A ++ RK ++ ++L VQA + R
Sbjct: 845 REKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEER 904
Query: 855 LHQRLRAEYLWRLEAEKM--RLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERE 912
Q ++ + + ++M RL +EE++ E++AKK RK ++ ++L R+ + E
Sbjct: 905 CDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKK------RKLEDECSELKRDIDDLE 958
Query: 913 L------KEKEAARRK-KELLEQM 929
L KEK A K K L E+M
Sbjct: 959 LTLAKVEKEKHATENKVKNLTEEM 982
Score = 34.7 bits (78), Expect = 1.0
Identities = 67/309 (21%), Positives = 121/309 (39%), Gaps = 36/309 (11%)
Query: 866 RLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEKEAARRKKEL 925
++E K R AE +K+R+++ EEA +H+ A L ++ A+ + E + +
Sbjct: 1160 QIEMNKKREAEFQKMRRDL------EEATLQHEATAAALRKKHADSVAELGEQIDNLQRV 1213
Query: 926 LEQMERARHE-PVNHSDMVDKMFGFLGTSGGLPGQEGQAPSGFEDLERGRREMVEE---- 980
+++E+ + E + D+ M + L + ED R EE
Sbjct: 1214 KQKLEKEKSEFKLELDDVTSNMEQIIKAKANLE----KMCRTLEDQMNEHRSKAEETQRS 1269
Query: 981 --DLDAALPLPDEDEEDLSEYKFAKFA--ATYFQGTTTHSYTRRPLKQPLLYHDDEGDQL 1036
DL + + +LS K A + +G T++ LK+ L ++E
Sbjct: 1270 VNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQL---EEEVKAK 1326
Query: 1037 AALAVWITILRFMGDLPEPKYHTAMSDGSEKIPVMTKIYETLGKKTYKRELQALQGEGEA 1096
ALA + R DL +Y +E V++K + + K E A+Q E
Sbjct: 1327 NALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEE- 1385
Query: 1097 QLPEGQKKSSVRHKLVHLTL-----------KKKSKLTEEVTKRLHDGESTVQGNSMLED 1145
L E +KK + R + + K K +L E+ + D E + + L D
Sbjct: 1386 -LEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAAL-D 1443
Query: 1146 RPTSNLEKL 1154
+ N +K+
Sbjct: 1444 KKQRNFDKI 1452
Score = 34.7 bits (78), Expect = 1.0
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 8/76 (10%)
Query: 876 EEEKLRKEMSAKK-----AKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQME 930
E EK+RK++ A+K A EEAE + ++ R E + E R+ E E+ME
Sbjct: 1525 ELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEME 1584
Query: 931 RARHEPVNHSDMVDKM 946
+A+ NH +VD +
Sbjct: 1585 QAKR---NHLRVVDSL 1597
Score = 33.9 bits (76), Expect = 1.8
Identities = 47/203 (23%), Positives = 81/203 (39%), Gaps = 22/203 (10%)
Query: 807 HQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLT-VQAYARGMIARRLHQRLRAEYLW 865
H QY+ ++ F+A L+ + RL ++T +QA +RG++AR +++L
Sbjct: 753 HNQYKFGHTKVF-FKAGLLG-LLEEMRDERLSRIITRIQAQSRGVLARMEYKKL------ 804
Query: 866 RLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEKEAARRKKEL 925
LE L + +R M K K ++ L + AERE KE A K+E
Sbjct: 805 -LERRDSLLVIQWNIRAFMGVKNWPW---MKLYFKIKPLLKS-AERE---KEMASMKEEF 856
Query: 926 LEQMERARHEPVNHSDMVDKMFGFLGTSGGLPGQEGQAPSGFEDLERGRREMVEEDLDAA 985
E ++ +KM L L Q D E ++++ +
Sbjct: 857 TRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLE 916
Query: 986 LPLPD-----EDEEDLSEYKFAK 1003
+ + EDEE+++ AK
Sbjct: 917 AKVKEMNERLEDEEEMNAELTAK 939
>gi|4885503 myosin IA [Homo sapiens]
Length = 1043
Score = 483 bits (1243), Expect = e-136
Identities = 281/763 (36%), Positives = 439/763 (57%), Gaps = 24/763 (3%)
Query: 66 GVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNK 125
GVED++ L L E +L+NL +RY + IYTY G+++++VNPYQ L IY PE I +Y +
Sbjct: 9 GVEDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKYQDY 68
Query: 126 KIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISG---QH 182
E+ PHI+A+A+ Y +++ RDQC +I+GESG+GKTE++KL++ ++AA+ G Q
Sbjct: 69 TFYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCGKGEQV 128
Query: 183 SWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRV 242
+ +++Q+L++ P+LEAFGNAKTIRN+NSSRFGKY+DI F+ +G+ G I YLLEKSR+
Sbjct: 129 NSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNYLLEKSRL 188
Query: 243 CRQALDERNYHVFYCMLEGMSEDQKKKLGLGQ-ASDYNYLAMGNCITCEGRVDSQEYANI 301
+Q ERN+H+FY +L G E K L L + + Y YL +G D+ + +
Sbjct: 189 VKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYL-NHEVSRVDGMDDASSFRAV 247
Query: 302 RSAMKVLMFTDTENWEISKLLAAILHLGN-LQYEARTFENLDACEVLFSPSLATAASLLE 360
+SAM V+ F++ E ++ ++ + +L LGN L + + A + + ++
Sbjct: 248 QSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDGRGVREIGEMVG 307
Query: 361 VNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYK 420
+N ++ L SRT+ T E V T L+ QA RDA K IY RLF WIV++IN +I
Sbjct: 308 LNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNRINESI-- 365
Query: 421 PPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLE 480
+ ++ +G+LDI+GFE NSFEQ IN+ NE LQQ F+ K EQEEY E
Sbjct: 366 --KVGIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEYKRE 423
Query: 481 SIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFP-KGTDTTMLHKLNSQHKLNANYI 539
I W +++ DN +I + I++++DEE P +D+T L KLN + +Y
Sbjct: 424 GIPWTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDSTFLAKLNQLFSKHGHYE 483
Query: 540 PPKNNHETQ----------FGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFI 589
+ + F I H+AG V Y F++KN D L D++Q + +++ +
Sbjct: 484 SKVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKAQHPLL 543
Query: 590 KQIFQADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDR 649
+ +F A + KR PT +QFK S+ +LM+ L + P ++RCIKPNE ++ F
Sbjct: 544 RSLFPEGNPKQA-SLKRPPTAGAQFKSSVAILMKNLYSKSPNYIRCIKPNEHQQRGQFSS 602
Query: 650 HLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMA 709
L Q RY G++E +R+RRAGY R + F+ERYR+L P + GD G + +
Sbjct: 603 DLVATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRLLSRSTWPHWNGGDREGVEKVLG 662
Query: 710 EAVLGTHDDWQIGKTKIFLKDHHDML-LEVERDKAITDRVILLQKVIRGFKDRSNFLKLK 768
E + + + GKTKIF++ + LE +R + L+QK+ RG++ R+++ ++
Sbjct: 663 ELSMSS-GELAFGKTKIFIRSPKTLFYLEEQRRLRLQQLATLIQKIYRGWRCRTHYQLMR 721
Query: 769 NAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYR 811
+ LI +RG+ +K YG ++ L +QA R K + YR
Sbjct: 722 KSQILISSWFRGNMQKKCYGKIKASVLLIQAFVRGWKARKNYR 764
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 81,837,023
Number of Sequences: 37866
Number of extensions: 3726850
Number of successful extensions: 19528
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 250
Number of HSP's successfully gapped in prelim test: 301
Number of HSP's that attempted gapping in prelim test: 12996
Number of HSP's gapped (non-prelim): 3866
length of query: 2175
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2057
effective length of database: 13,779,330
effective search space: 28344081810
effective search space used: 28344081810
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.