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Search of human proteins with 188528692
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo
sapiens]
(605 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo sapi... 1242 0.0
gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens] 721 0.0
gi|62243586 ubiquitin-specific protease 21 [Homo sapiens] 339 5e-93
gi|74027267 ubiquitin-specific protease 21 [Homo sapiens] 339 5e-93
gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens] 271 1e-72
gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens] 271 1e-72
gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens] 271 1e-72
gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens] 196 7e-50
gi|150010639 ubiquitin thiolesterase 22 [Homo sapiens] 173 5e-43
gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens] 170 4e-42
gi|14149627 ubiquitin specific peptidase 15 [Homo sapiens] 166 7e-41
gi|40795667 ubiquitin specific protease 4 isoform b [Homo sapiens] 160 3e-39
gi|40795665 ubiquitin specific protease 4 isoform a [Homo sapiens] 159 7e-39
gi|45267835 ubiquitin specific protease 50 [Homo sapiens] 158 2e-38
gi|24234683 ubiquitin specific peptidase 11 [Homo sapiens] 154 2e-37
gi|109638751 ubiquitin specific protease 6 [Homo sapiens] 152 7e-37
gi|41152235 ubiquitin specific protease 51 [Homo sapiens] 152 9e-37
gi|22550104 ubiquitin specific protease 32 [Homo sapiens] 152 9e-37
gi|57529246 ubiquitin thioesterase 19 [Homo sapiens] 150 3e-36
gi|42516561 ubiquitin specific protease 33 isoform 3 [Homo sapiens] 136 5e-32
gi|42516567 ubiquitin specific protease 33 isoform 1 [Homo sapiens] 133 4e-31
gi|42516565 ubiquitin specific protease 33 isoform 2 [Homo sapiens] 133 4e-31
gi|169217654 PREDICTED: similar to deubiquitinating enzyme DUB1 ... 130 3e-30
gi|239758075 PREDICTED: similar to deubiquitinating enzyme DUB1 ... 130 3e-30
gi|113415490 PREDICTED: similar to deubiquitinating enzyme 1 [Ho... 130 3e-30
gi|113415488 PREDICTED: similar to deubiquitinating enzyme 1 [Ho... 130 3e-30
gi|113415486 PREDICTED: similar to deubiquitinating enzyme 1 [Ho... 130 3e-30
gi|113415484 PREDICTED: similar to deubiquitinating enzyme 1 [Ho... 130 3e-30
gi|113415482 PREDICTED: Ubiquitin carboxyl-terminal hydrolase 17... 130 3e-30
gi|113415480 PREDICTED: similar to deubiquitinating enzyme 1 [Ho... 130 3e-30
>gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo
sapiens]
Length = 605
Score = 1242 bits (3213), Expect = 0.0
Identities = 605/605 (100%), Positives = 605/605 (100%)
Query: 1 MSQLSSTLKRYTESARYTDAHYAKSGYGAYTPSSYGANLAASLLEKEKLGFKPVPTSSFL 60
MSQLSSTLKRYTESARYTDAHYAKSGYGAYTPSSYGANLAASLLEKEKLGFKPVPTSSFL
Sbjct: 1 MSQLSSTLKRYTESARYTDAHYAKSGYGAYTPSSYGANLAASLLEKEKLGFKPVPTSSFL 60
Query: 61 TRPRTYGPSSLLDYDRGRPLLRPDITGGGKRAESQTRGTERPLGSGLSGGSGFPYGVTNN 120
TRPRTYGPSSLLDYDRGRPLLRPDITGGGKRAESQTRGTERPLGSGLSGGSGFPYGVTNN
Sbjct: 61 TRPRTYGPSSLLDYDRGRPLLRPDITGGGKRAESQTRGTERPLGSGLSGGSGFPYGVTNN 120
Query: 121 CLSYLPINAYDQGVTLTQKLDSQSDLARDFSSLRTSDSYRIDPRNLGRSPMLARTRKELC 180
CLSYLPINAYDQGVTLTQKLDSQSDLARDFSSLRTSDSYRIDPRNLGRSPMLARTRKELC
Sbjct: 121 CLSYLPINAYDQGVTLTQKLDSQSDLARDFSSLRTSDSYRIDPRNLGRSPMLARTRKELC 180
Query: 181 TLQGLYQTASCPEYLVDYLENYGRKGSASQVPSQAPPSRVPEIISPTYRPIGRYTLWETG 240
TLQGLYQTASCPEYLVDYLENYGRKGSASQVPSQAPPSRVPEIISPTYRPIGRYTLWETG
Sbjct: 181 TLQGLYQTASCPEYLVDYLENYGRKGSASQVPSQAPPSRVPEIISPTYRPIGRYTLWETG 240
Query: 241 KGQAPGPSRSSSPGRDGMNSKSAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLY 300
KGQAPGPSRSSSPGRDGMNSKSAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLY
Sbjct: 241 KGQAPGPSRSSSPGRDGMNSKSAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLY 300
Query: 301 MRDLHHGSNAHTALVEEFAKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQE 360
MRDLHHGSNAHTALVEEFAKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQE
Sbjct: 301 MRDLHHGSNAHTALVEEFAKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQE 360
Query: 361 FLRFLLDGLHNEVNRVTLRPKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLK 420
FLRFLLDGLHNEVNRVTLRPKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLK
Sbjct: 361 FLRFLLDGLHNEVNRVTLRPKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLK 420
Query: 421 SSLTCTDCGYCSTVFDPFWDLSLPIAKRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCR 480
SSLTCTDCGYCSTVFDPFWDLSLPIAKRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCR
Sbjct: 421 SSLTCTDCGYCSTVFDPFWDLSLPIAKRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCR 480
Query: 481 GRKRCIKKFSIQRFPKILVLHLKRFSESRIRTSKLTTFVNFPLRDLDLREFASENTNHAV 540
GRKRCIKKFSIQRFPKILVLHLKRFSESRIRTSKLTTFVNFPLRDLDLREFASENTNHAV
Sbjct: 481 GRKRCIKKFSIQRFPKILVLHLKRFSESRIRTSKLTTFVNFPLRDLDLREFASENTNHAV 540
Query: 541 YNLYAVSNHSGTTMGGHYTAYCRSPGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFYELAS 600
YNLYAVSNHSGTTMGGHYTAYCRSPGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFYELAS
Sbjct: 541 YNLYAVSNHSGTTMGGHYTAYCRSPGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFYELAS 600
Query: 601 PPSRM 605
PPSRM
Sbjct: 601 PPSRM 605
>gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens]
Length = 396
Score = 721 bits (1861), Expect = 0.0
Identities = 347/347 (100%), Positives = 347/347 (100%)
Query: 259 NSKSAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTALVEEF 318
NSKSAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTALVEEF
Sbjct: 50 NSKSAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTALVEEF 109
Query: 319 AKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTL 378
AKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTL
Sbjct: 110 AKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTL 169
Query: 379 RPKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPF 438
RPKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPF
Sbjct: 170 RPKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPF 229
Query: 439 WDLSLPIAKRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKIL 498
WDLSLPIAKRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKIL
Sbjct: 230 WDLSLPIAKRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKIL 289
Query: 499 VLHLKRFSESRIRTSKLTTFVNFPLRDLDLREFASENTNHAVYNLYAVSNHSGTTMGGHY 558
VLHLKRFSESRIRTSKLTTFVNFPLRDLDLREFASENTNHAVYNLYAVSNHSGTTMGGHY
Sbjct: 290 VLHLKRFSESRIRTSKLTTFVNFPLRDLDLREFASENTNHAVYNLYAVSNHSGTTMGGHY 349
Query: 559 TAYCRSPGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFYELASPPSRM 605
TAYCRSPGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFYELASPPSRM
Sbjct: 350 TAYCRSPGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFYELASPPSRM 396
>gi|62243586 ubiquitin-specific protease 21 [Homo sapiens]
Length = 565
Score = 339 bits (869), Expect = 5e-93
Identities = 177/357 (49%), Positives = 233/357 (65%), Gaps = 20/357 (5%)
Query: 265 GLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTALVEEFAKLIQT 324
G GLRNLGNTCF+N++LQCLS+TR LRD+CL+R + +++ G A L E FA +I
Sbjct: 210 GHVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDFRQEVPGGGRAQE-LTEAFADVIGA 268
Query: 325 IWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNR--------- 375
+W + V+P+ F+ Q+Y P F GY+QQDAQEFL+ L++ LH E+NR
Sbjct: 269 LWHPDSCEAVNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLHLEINRRGRRAPPIL 328
Query: 376 ----VTLRPKSNPENLDH--LPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCG 429
V P+ L+ L DD++ MW++YLEREDS+I DLFVGQLKS L C CG
Sbjct: 329 ANGPVPSPPRRGGALLEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQACG 388
Query: 430 YCSTVFDPFWDLSLPIAKRGYP--EVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIK 487
Y ST F+ F DLSLPI K+G+ +V+L DC LFTKE+ L+ + P C RCR + R K
Sbjct: 389 YRSTTFEVFCDLSLPIPKKGFAGGKVSLRDCFNLFTKEEELESENAPVCDRCRQKTRSTK 448
Query: 488 KFSIQRFPKILVLHLKRFSESRIRTSKLTTFVNFPLRDLDLREFASENTNHAVYNLYAVS 547
K ++QRFP+ILVLHL RFS SR K + V+FPL+ L L +FAS+ VY LYA+
Sbjct: 449 KLTVQRFPRILVLHLNRFSASRGSIKKSSVGVDFPLQRLSLGDFASDKAGSPVYQLYALC 508
Query: 548 NHSGTTMGGHYTAYCRSPGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFYELASPPSR 604
NHSG+ GHYTA CR TG WH +NDS V+P+S +QV +S+ Y+LFY+L P R
Sbjct: 509 NHSGSVHYGHYTALCRCQ-TG-WHVYNDSRVSPVSENQVASSEGYVLFYQLMQEPPR 563
>gi|74027267 ubiquitin-specific protease 21 [Homo sapiens]
Length = 565
Score = 339 bits (869), Expect = 5e-93
Identities = 177/357 (49%), Positives = 233/357 (65%), Gaps = 20/357 (5%)
Query: 265 GLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTALVEEFAKLIQT 324
G GLRNLGNTCF+N++LQCLS+TR LRD+CL+R + +++ G A L E FA +I
Sbjct: 210 GHVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDFRQEVPGGGRAQE-LTEAFADVIGA 268
Query: 325 IWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNR--------- 375
+W + V+P+ F+ Q+Y P F GY+QQDAQEFL+ L++ LH E+NR
Sbjct: 269 LWHPDSCEAVNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLHLEINRRGRRAPPIL 328
Query: 376 ----VTLRPKSNPENLDH--LPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCG 429
V P+ L+ L DD++ MW++YLEREDS+I DLFVGQLKS L C CG
Sbjct: 329 ANGPVPSPPRRGGALLEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQACG 388
Query: 430 YCSTVFDPFWDLSLPIAKRGYP--EVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIK 487
Y ST F+ F DLSLPI K+G+ +V+L DC LFTKE+ L+ + P C RCR + R K
Sbjct: 389 YRSTTFEVFCDLSLPIPKKGFAGGKVSLRDCFNLFTKEEELESENAPVCDRCRQKTRSTK 448
Query: 488 KFSIQRFPKILVLHLKRFSESRIRTSKLTTFVNFPLRDLDLREFASENTNHAVYNLYAVS 547
K ++QRFP+ILVLHL RFS SR K + V+FPL+ L L +FAS+ VY LYA+
Sbjct: 449 KLTVQRFPRILVLHLNRFSASRGSIKKSSVGVDFPLQRLSLGDFASDKAGSPVYQLYALC 508
Query: 548 NHSGTTMGGHYTAYCRSPGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFYELASPPSR 604
NHSG+ GHYTA CR TG WH +NDS V+P+S +QV +S+ Y+LFY+L P R
Sbjct: 509 NHSGSVHYGHYTALCRCQ-TG-WHVYNDSRVSPVSENQVASSEGYVLFYQLMQEPPR 563
>gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 271 bits (694), Expect = 1e-72
Identities = 144/343 (41%), Positives = 200/343 (58%), Gaps = 6/343 (1%)
Query: 262 SAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGS--NAHTALVEEFA 319
S L GLRNLGNTC+MNSILQCL N L DY + Y D++ + + EEF
Sbjct: 772 SGPALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFG 831
Query: 320 KLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLR 379
+++ +WT +SP +FK I + +F GY+QQD+QE L FL+DGLH ++N+ R
Sbjct: 832 IIMKALWTGQYR-YISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNR 890
Query: 380 PKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFW 439
+ EN DHL D + W+K+ + +S I LF GQ KS++ C C S F+ F
Sbjct: 891 KRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFM 950
Query: 440 DLSLPIAKRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILV 499
LSLP+A + TL DC+RLF+KE+ L + + C CR R+ +KK I + P +L+
Sbjct: 951 YLSLPLASTS--KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLL 1008
Query: 500 LHLKRFSESRIRTSKLTTFVNFPLRDLDLREFA-SENTNHAVYNLYAVSNHSGTTMGGHY 558
+HLKRFS KL T V+FPL +LDL ++ N YNL++VSNH G GGHY
Sbjct: 1009 VHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHY 1068
Query: 559 TAYCRSPGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFYELASP 601
TAYC++ W F+D V+ +S S V++S AY+LFY P
Sbjct: 1069 TAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYILFYTSLGP 1111
>gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 271 bits (694), Expect = 1e-72
Identities = 144/343 (41%), Positives = 200/343 (58%), Gaps = 6/343 (1%)
Query: 262 SAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGS--NAHTALVEEFA 319
S L GLRNLGNTC+MNSILQCL N L DY + Y D++ + + EEF
Sbjct: 772 SGPALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFG 831
Query: 320 KLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLR 379
+++ +WT +SP +FK I + +F GY+QQD+QE L FL+DGLH ++N+ R
Sbjct: 832 IIMKALWTGQYR-YISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNR 890
Query: 380 PKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFW 439
+ EN DHL D + W+K+ + +S I LF GQ KS++ C C S F+ F
Sbjct: 891 KRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFM 950
Query: 440 DLSLPIAKRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILV 499
LSLP+A + TL DC+RLF+KE+ L + + C CR R+ +KK I + P +L+
Sbjct: 951 YLSLPLASTS--KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLL 1008
Query: 500 LHLKRFSESRIRTSKLTTFVNFPLRDLDLREFA-SENTNHAVYNLYAVSNHSGTTMGGHY 558
+HLKRFS KL T V+FPL +LDL ++ N YNL++VSNH G GGHY
Sbjct: 1009 VHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHY 1068
Query: 559 TAYCRSPGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFYELASP 601
TAYC++ W F+D V+ +S S V++S AY+LFY P
Sbjct: 1069 TAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYILFYTSLGP 1111
>gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 271 bits (694), Expect = 1e-72
Identities = 144/343 (41%), Positives = 200/343 (58%), Gaps = 6/343 (1%)
Query: 262 SAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGS--NAHTALVEEFA 319
S L GLRNLGNTC+MNSILQCL N L DY + Y D++ + + EEF
Sbjct: 772 SGPALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFG 831
Query: 320 KLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLR 379
+++ +WT +SP +FK I + +F GY+QQD+QE L FL+DGLH ++N+ R
Sbjct: 832 IIMKALWTGQYR-YISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNR 890
Query: 380 PKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFW 439
+ EN DHL D + W+K+ + +S I LF GQ KS++ C C S F+ F
Sbjct: 891 KRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFM 950
Query: 440 DLSLPIAKRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILV 499
LSLP+A + TL DC+RLF+KE+ L + + C CR R+ +KK I + P +L+
Sbjct: 951 YLSLPLASTS--KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLL 1008
Query: 500 LHLKRFSESRIRTSKLTTFVNFPLRDLDLREFA-SENTNHAVYNLYAVSNHSGTTMGGHY 558
+HLKRFS KL T V+FPL +LDL ++ N YNL++VSNH G GGHY
Sbjct: 1009 VHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHY 1068
Query: 559 TAYCRSPGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFYELASP 601
TAYC++ W F+D V+ +S S V++S AY+LFY P
Sbjct: 1069 TAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYILFYTSLGP 1111
>gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens]
Length = 520
Score = 196 bits (497), Expect = 7e-50
Identities = 139/366 (37%), Positives = 189/366 (51%), Gaps = 38/366 (10%)
Query: 260 SKSAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNA-----HT-- 312
S +A GLRNLGNTCFMN+ILQ LSN + Y + L +L +G A HT
Sbjct: 152 STTAICATGLRNLGNTCFMNAILQSLSNIEQFCCY-FKELPAVELRNGKTAGRRTYHTRS 210
Query: 313 ------ALVEEFAKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLL 366
+LVEEF K + +W S SP + + P F GY QQDA EF+R+LL
Sbjct: 211 QGDNNVSLVEEFRKTLCALWQGSQT-AFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLL 269
Query: 367 DGLHNEVNRVTLRPKSNPENLDHLPDDEKGRQMWRKY-LEREDSRIGDLFVGQLKSSLTC 425
D LH E L+ N + + + K + + + +F G L++ + C
Sbjct: 270 DHLHLE-----LQGGFNGVSRSAILQENSTLSASNKCCINGASTVVTAIFGGILQNEVNC 324
Query: 426 TDCGYCSTVFDPFWDLSLPI-----AKRGY-----PEVTLMDCMRLFTKEDVLDGDEKPT 475
CG S FDPF DLSL I +KR P +L DC+R FT + LD E
Sbjct: 325 LICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELYM 384
Query: 476 CCRCRGRKRCIKKFSIQRFPKILVLHLKRFSESRIRTSKLTTFVNFPLRDLDLREFASEN 535
C +C+ +++ KKF IQ+ PK+L LHLKRF + +K+ T+V FPLR LD++ + E
Sbjct: 385 CHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYVEFPLRGLDMKCYLLEP 444
Query: 536 TN----HAVYNLYAVSNHSGTTMG-GHYTAYCRSPGTGEWHTFNDSSVTPMSSSQVRTSD 590
N +Y+L AV H G+ +G GHYTAY + G W FNDS+VT V +
Sbjct: 445 ENSGPESCLYDLAAVVVHHGSGVGSGHYTAY--ATHEGRWFHFNDSTVTLTDEETVVKAK 502
Query: 591 AYLLFY 596
AY+LFY
Sbjct: 503 AYILFY 508
>gi|150010639 ubiquitin thiolesterase 22 [Homo sapiens]
Length = 525
Score = 173 bits (438), Expect = 5e-43
Identities = 123/401 (30%), Positives = 180/401 (44%), Gaps = 64/401 (15%)
Query: 233 RYTLWETGKGQAPGPSRSSSPGRDGMNSKSAQGLAGLRNLGNTCFMNSILQCLSNTRELR 292
+++ WE K + +P R + S GL GL NLGNTCFMN I+Q L++T LR
Sbjct: 144 KFSTWEPTKRELE--LLKHNPKRRKITSNCTIGLRGLINLGNTCFMNCIVQALTHTPLLR 201
Query: 293 DYCLQRLYMRDLHHGSNAHTALVEEFAKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVG 352
D+ L + ++ S+ LV E + L Q ++ + + P + + +A G
Sbjct: 202 DFFLSDRHRCEMQSPSSC---LVCEMSSLFQEFYSGHRSPHI-PYKLLHLVWTHARHLAG 257
Query: 353 YNQQDAQEFLRFLLDGLHNEVNRVTLRPKSNPENLDHLPDDEKGRQMWRKYLEREDSRIG 412
Y QQDA EFL LD LH H D+ G++ + I
Sbjct: 258 YEQQDAHEFLIAALDVLHR-----------------HCKGDDNGKKANNP--NHCNCIID 298
Query: 413 DLFVGQLKSSLTCTDCGYCSTVFDPFWDLSLPIAKRGYP--------------------- 451
+F G L+S +TC C ST DPFWD+SL + P
Sbjct: 299 QIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPFWPLSPGSEGNVVNGESHVSG 358
Query: 452 EVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRFSESRIR 511
TL DC+R FT+ + L K C C + K+ ++++ P + HLKRF S
Sbjct: 359 TTTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRFEHSAKL 418
Query: 512 TSKLTTFVNFPLRDLDLREFASEN----------------TNHAVYNLYAVSNHSGTTMG 555
K+TT+V+FPL +LD+ F + + N Y+L+AV NH GT
Sbjct: 419 RRKITTYVSFPL-ELDMTPFMASSKESRMNGQYQQPTDSLNNDNKYSLFAVVNHQGTLES 477
Query: 556 GHYTAYCRSPGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFY 596
GHYT++ R +W +D+ +T S V S+ YLLFY
Sbjct: 478 GHYTSFIRQ-HKDQWFKCDDAIITKASIKDVLDSEGYLLFY 517
>gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens]
Length = 438
Score = 170 bits (430), Expect = 4e-42
Identities = 128/445 (28%), Positives = 199/445 (44%), Gaps = 67/445 (15%)
Query: 191 CPEYLVDY-LENYGRKGSASQVPSQAPPSRVPEIISPTYRPIG-RYTLWETGKGQAPGPS 248
C +Y+ D +E ++ + QA S + +G ++ WET K +
Sbjct: 2 CKDYVYDKDIEQIAKEEQGEALKLQASTSTEVSHQQCSVPGLGEKFPTWETTKPELE--L 59
Query: 249 RSSSPGRDGMNSKSAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGS 308
+P R + S GL GL NLGNTCFMN I+Q L++T LRD+ L + ++
Sbjct: 60 LGHNPRRRRITSSFTIGLRGLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEM---P 116
Query: 309 NAHTALVEEFAKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDG 368
+ LV E + L + +++ +P+ V P + + +A GY QQDA EFL LD
Sbjct: 117 SPELCLVCEMSSLFRELYSGNPSPHV-PYKLLHLVWIHARHLAGYRQQDAHEFLIAALDV 175
Query: 369 LHNEVNRVTL-RPKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTD 427
LH + + +NP + + + D +F G L+S +TC
Sbjct: 176 LHRHCKGDDVGKAANNPNHCNCIIDQ--------------------IFTGGLQSDVTCQA 215
Query: 428 CGYCSTVFDPFWDLSLPI-------------------AKRGYPEVT-LMDCMRLFTKEDV 467
C ST DP WD+SL + + P +T L DC+R FT+ +
Sbjct: 216 CHGVSTTIDPCWDISLDLPGSCTSFWPMSPGRESSVNGESHIPGITTLTDCLRRFTRPEH 275
Query: 468 LDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRFSESRIRTSKLTTFVNFPLRDLD 527
L K C C+ + K+ ++ + P + H KRF S + K+TT+++FPL +LD
Sbjct: 276 LGSSAKIKCGSCQSYQESTKQLTMNKLPVVACFHFKRFEHSAKQRRKITTYISFPL-ELD 334
Query: 528 LREF----------------ASENTNHAVYNLYAVSNHSGTTMGGHYTAYCRSPGTGEWH 571
+ F + N Y+L+AV NH GT GHYT++ R +W
Sbjct: 335 MTPFMASSKESRMNGQLQLPTNSGNNENKYSLFAVVNHQGTLESGHYTSFIRH-HKDQWF 393
Query: 572 TFNDSSVTPMSSSQVRTSDAYLLFY 596
+D+ +T S V S+ YLLFY
Sbjct: 394 KCDDAVITKASIKDVLDSEGYLLFY 418
>gi|14149627 ubiquitin specific peptidase 15 [Homo sapiens]
Length = 952
Score = 166 bits (419), Expect = 7e-41
Identities = 87/197 (44%), Positives = 117/197 (59%), Gaps = 7/197 (3%)
Query: 251 SSPGRDGMNSKSAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGS-- 308
S PGR+ GL GL NLGNTCFMNS +QCLSNT L +Y L Y +L+ +
Sbjct: 248 SEPGRNN----EQPGLCGLSNLGNTCFMNSAIQCLSNTPPLTEYFLNDKYQEELNFDNPL 303
Query: 309 NAHTALVEEFAKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDG 368
+ + +A+LI+ +W S V+P FKTQ+ R+AP+F GY QQD QE L FLLDG
Sbjct: 304 GMRGEIAKSYAELIKQMW-SGKFSYVTPRAFKTQVGRFAPQFSGYQQQDCQELLAFLLDG 362
Query: 369 LHNEVNRVTLRPKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDC 428
LH ++NR+ +P ++ D PD + W +L+R DS I D+F G KS+L C +C
Sbjct: 363 LHEDLNRIRKKPYIQLKDADGRPDKVVAEEAWENHLKRNDSIIVDIFHGLFKSTLVCPEC 422
Query: 429 GYCSTVFDPFWDLSLPI 445
S FDPF L+LP+
Sbjct: 423 AKISVTFDPFCYLTLPL 439
Score = 131 bits (329), Expect = 2e-30
Identities = 65/148 (43%), Positives = 91/148 (61%), Gaps = 1/148 (0%)
Query: 451 PEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRFSESRI 510
P V L DC+ LFT ++ L ++ C C+ ++ KK + P +LV+HLKRFS SR
Sbjct: 755 PFVKLKDCIELFTTKEKLGAEDPWYCPNCKEHQQATKKLDLWSLPPVLVVHLKRFSYSRY 814
Query: 511 RTSKLTTFVNFPLRDLDLREF-ASENTNHAVYNLYAVSNHSGTTMGGHYTAYCRSPGTGE 569
KL T V+FP+ DLD+ EF + N YNL AVSNH G GGHYTA+ ++ G+
Sbjct: 815 MRDKLDTLVDFPINDLDMSEFLINPNAGPCRYNLIAVSNHYGGMGGGHYTAFAKNKDDGK 874
Query: 570 WHTFNDSSVTPMSSSQVRTSDAYLLFYE 597
W+ F+DSSV+ S Q+ + AY+LFY+
Sbjct: 875 WYYFDDSSVSTASEDQIVSKAAYVLFYQ 902
>gi|40795667 ubiquitin specific protease 4 isoform b [Homo sapiens]
Length = 916
Score = 160 bits (405), Expect = 3e-39
Identities = 91/215 (42%), Positives = 123/215 (57%), Gaps = 8/215 (3%)
Query: 233 RYTLWETGKGQAPGPSRSSSPGRDGMNSKSAQGLAGLRNLGNTCFMNSILQCLSNTRELR 292
R TL G G + + P +S GL GL NLGNTCFMNS LQCLSNT L
Sbjct: 226 RQTLQSNGSGFSASYNCQEPP-----SSHIQPGLCGLGNLGNTCFMNSALQCLSNTAPLT 280
Query: 293 DYCLQRLYMRDLHHGS--NAHTALVEEFAKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRF 350
DY L+ Y +++ + + E +A+LI+ +W S + V+P FKTQ+ R+AP+F
Sbjct: 281 DYFLKDEYEAEINRDNPLGMKGEIAEAYAELIKQMW-SGRDAHVAPRMFKTQVGRFAPQF 339
Query: 351 VGYNQQDAQEFLRFLLDGLHNEVNRVTLRPKSNPENLDHLPDDEKGRQMWRKYLEREDSR 410
GY QQD+QE L FLLDGLH ++NRV +P ++ + PD ++ W + R DS
Sbjct: 340 SGYQQQDSQELLAFLLDGLHEDLNRVKKKPYLELKDANGRPDAVVAKEAWENHRLRNDSV 399
Query: 411 IGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLSLPI 445
I D F G KS+L C +C S FDPF L+LP+
Sbjct: 400 IVDTFHGLFKSTLVCPECAKVSVTFDPFCYLTLPL 434
Score = 123 bits (309), Expect = 4e-28
Identities = 65/152 (42%), Positives = 90/152 (59%), Gaps = 1/152 (0%)
Query: 447 KRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRFS 506
K+ V L DC+ LFT + L + C C+ ++ KKF + PKILV+HLKRFS
Sbjct: 723 KKKKTTVALRDCIELFTTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPKILVVHLKRFS 782
Query: 507 ESRIRTSKLTTFVNFPLRDLDLREFASE-NTNHAVYNLYAVSNHSGTTMGGHYTAYCRSP 565
+R KL T V FP+R L++ EF + VY+L AVSNH G GHYTAY ++
Sbjct: 783 YNRYWRDKLDTVVEFPIRGLNMSEFVCNLSARPYVYDLIAVSNHYGAMGVGHYTAYAKNK 842
Query: 566 GTGEWHTFNDSSVTPMSSSQVRTSDAYLLFYE 597
G+W+ F+DS+V+ S Q+ T AY+LFY+
Sbjct: 843 LNGKWYYFDDSNVSLASEDQIVTKAAYVLFYQ 874
>gi|40795665 ubiquitin specific protease 4 isoform a [Homo sapiens]
Length = 963
Score = 159 bits (402), Expect = 7e-39
Identities = 117/356 (32%), Positives = 166/356 (46%), Gaps = 34/356 (9%)
Query: 122 LSYLPINAYDQGVTLTQKLDSQSDLARDFSSLRTSDSYRIDPRNLGRSPMLARTR----- 176
+ + + Y + L + D + L+ FS T + + R L P TR
Sbjct: 128 VKHCKVEVYLLELKLCENSDPTNVLSCHFSKADTIATIEKEMRKLFNIPAERETRLWNKY 187
Query: 177 -----KELCTLQGLYQTASCPEYLVDYLENYGRKGS----ASQVPSQAPPSR----VPEI 223
++L L Q A + V +E G+ Q S PSR P+
Sbjct: 188 MSNTYEQLSKLDNTVQDAGLYQGQVLVIEPQNEDGTWPRQTLQSKSSTAPSRNFTTSPKS 247
Query: 224 ISPTYRPIGRYTLWETGKGQAPGPSRSSSPGRDGM------------NSKSAQGLAGLRN 271
+ Y + +L G + SS R G +S GL GL N
Sbjct: 248 SASPYSSVSA-SLIANGDSTSTCGMHSSGVSRGGSGFSASYNCQEPPSSHIQPGLCGLGN 306
Query: 272 LGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGS--NAHTALVEEFAKLIQTIWTSS 329
LGNTCFMNS LQCLSNT L DY L+ Y +++ + + E +A+LI+ +W S
Sbjct: 307 LGNTCFMNSALQCLSNTAPLTDYFLKDEYEAEINRDNPLGMKGEIAEAYAELIKQMW-SG 365
Query: 330 PNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLRPKSNPENLDH 389
+ V+P FKTQ+ R+AP+F GY QQD+QE L FLLDGLH ++NRV +P ++ +
Sbjct: 366 RDAHVAPRMFKTQVGRFAPQFSGYQQQDSQELLAFLLDGLHEDLNRVKKKPYLELKDANG 425
Query: 390 LPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLSLPI 445
PD ++ W + R DS I D F G KS+L C +C S FDPF L+LP+
Sbjct: 426 RPDAVVAKEAWENHRLRNDSVIVDTFHGLFKSTLVCPECAKVSVTFDPFCYLTLPL 481
Score = 123 bits (309), Expect = 4e-28
Identities = 65/152 (42%), Positives = 90/152 (59%), Gaps = 1/152 (0%)
Query: 447 KRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRFS 506
K+ V L DC+ LFT + L + C C+ ++ KKF + PKILV+HLKRFS
Sbjct: 770 KKKKTTVALRDCIELFTTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPKILVVHLKRFS 829
Query: 507 ESRIRTSKLTTFVNFPLRDLDLREFASE-NTNHAVYNLYAVSNHSGTTMGGHYTAYCRSP 565
+R KL T V FP+R L++ EF + VY+L AVSNH G GHYTAY ++
Sbjct: 830 YNRYWRDKLDTVVEFPIRGLNMSEFVCNLSARPYVYDLIAVSNHYGAMGVGHYTAYAKNK 889
Query: 566 GTGEWHTFNDSSVTPMSSSQVRTSDAYLLFYE 597
G+W+ F+DS+V+ S Q+ T AY+LFY+
Sbjct: 890 LNGKWYYFDDSNVSLASEDQIVTKAAYVLFYQ 921
>gi|45267835 ubiquitin specific protease 50 [Homo sapiens]
Length = 339
Score = 158 bits (399), Expect = 2e-38
Identities = 106/312 (33%), Positives = 156/312 (50%), Gaps = 13/312 (4%)
Query: 259 NSKSAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHG--SNAHTALVE 316
N QG+ GL NLGNTC +N+I QCL + L +Y L Y+ L + + +
Sbjct: 36 NQPHFQGVTGLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQKFLLPSDCSEVAT 95
Query: 317 EFAKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRV 376
FA L+ +W +D VSP F + + P F QQDAQEFL +L+ LH + +
Sbjct: 96 AFAYLMTDMWLGD-SDCVSPEIFWSALGNLYPAFTKKMQQDAQEFLICVLNELHEALKKY 154
Query: 377 TLRPKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFD 436
+ + E ++ RK++ E S I LF QL S+ C C C+ +
Sbjct: 155 HYSRRRSYEK-------GSTQRCCRKWITTETSIITQLFEEQLNYSIVCLKCEKCTYKNE 207
Query: 437 PFWDLSLPIAKRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPK 496
F SLPI + E +L DC++ F ++D L + + C C ++ + SI + PK
Sbjct: 208 VFTVFSLPIPSKY--ECSLRDCLQCFFQQDALTWNNEIHCSFCETKQETAVRASISKAPK 265
Query: 497 ILVLHLKRFSESRIRTSKLTTFVNFPLRDLDLREF-ASENTNHAVYNLYAVSNHSGTTMG 555
I++ HLKRF KL T +++PL +LDL + S + YNL AV NH G G
Sbjct: 266 IIIFHLKRFDIQGTTKRKLRTDIHYPLTNLDLTPYICSIFRKYPKYNLCAVVNHFGDLDG 325
Query: 556 GHYTAYCRSPGT 567
GHYTA+C++ T
Sbjct: 326 GHYTAFCKNSVT 337
>gi|24234683 ubiquitin specific peptidase 11 [Homo sapiens]
Length = 963
Score = 154 bits (389), Expect = 2e-37
Identities = 85/221 (38%), Positives = 119/221 (53%), Gaps = 8/221 (3%)
Query: 232 GRYTLWETGKGQAPGPSRSSSPGRDGMNS-----KSAQGLAGLRNLGNTCFMNSILQCLS 286
G+ + ET K PS + M+ K G+ GL NLGNTCFMNS LQCLS
Sbjct: 269 GQLIIMETRKKDGTWPSAQLHVMNNNMSEEDEDFKGQPGICGLTNLGNTCFMNSALQCLS 328
Query: 287 NTRELRDYCLQRLYMRDLHHGS--NAHTALVEEFAKLIQTIWTSSPNDVVSPSEFKTQIQ 344
N +L +Y L Y+ +L+ + + E +A L++ W+ +V P FK ++
Sbjct: 329 NVPQLTEYFLNNCYLEELNFRNPLGMKGEIAEAYADLVKQAWSGHHRSIV-PHVFKNKVG 387
Query: 345 RYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLRPKSNPENLDHLPDDEKGRQMWRKYL 404
+A +F+GY Q D+QE L FLLDGLH ++NRV + + PD E ++ W+ +
Sbjct: 388 HFASQFLGYQQHDSQELLSFLLDGLHEDLNRVKKKEYVELCDAAGRPDQEVAQEAWQNHK 447
Query: 405 EREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLSLPI 445
R DS I D F G KS+L C DCG S FDPF LS+P+
Sbjct: 448 RRNDSVIVDTFHGLFKSTLVCPDCGNVSVTFDPFCYLSVPL 488
Score = 124 bits (312), Expect = 2e-28
Identities = 59/150 (39%), Positives = 90/150 (60%), Gaps = 5/150 (3%)
Query: 453 VTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRFSESRIRT 512
V L +C+ LFT + L+ + C C+ + KK + P+IL++HLKRFS ++
Sbjct: 779 VRLQECIELFTTVETLEKENPWYCPSCKQHQLATKKLDLWMLPEILIIHLKRFSYTKFSR 838
Query: 513 SKLTTFVNFPLRDLDLREFASENTNHA-----VYNLYAVSNHSGTTMGGHYTAYCRSPGT 567
KL T V FP+RDLD EF + N + Y+L AVSNH G GHYT + + +
Sbjct: 839 EKLDTLVEFPIRDLDFSEFVIQPQNESNPELYKYDLIAVSNHYGGMRDGHYTTFACNKDS 898
Query: 568 GEWHTFNDSSVTPMSSSQVRTSDAYLLFYE 597
G+WH F+D+SV+P++ +Q+ + AY+LFY+
Sbjct: 899 GQWHYFDDNSVSPVNENQIESKAAYVLFYQ 928
>gi|109638751 ubiquitin specific protease 6 [Homo sapiens]
Length = 1406
Score = 152 bits (385), Expect = 7e-37
Identities = 82/204 (40%), Positives = 118/204 (57%), Gaps = 7/204 (3%)
Query: 256 DGMNSKSAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHH----GSNAH 311
D + +G GL NLGNTCFMNS +QC+SNT+ L Y + ++ +L+ G H
Sbjct: 521 DRQKVPTEKGATGLSNLGNTCFMNSSIQCVSNTQPLTQYFISGRHLYELNRTNPIGMKGH 580
Query: 312 TALVEEFAKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHN 371
A + L+Q +W+ + V +P + + I +YAP+F G+ QQD+QE L FLLDGLH
Sbjct: 581 MAKC--YGDLVQELWSGTQKSV-APLKLRRTIAKYAPKFDGFQQQDSQELLAFLLDGLHE 637
Query: 372 EVNRVTLRPKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYC 431
++NRV +P ++ D PD E + W +L R S I DLF GQL+S + C CG+
Sbjct: 638 DLNRVHEKPYVELKDSDGRPDWEVAAEAWDNHLRRNRSIIVDLFHGQLRSQVKCKTCGHI 697
Query: 432 STVFDPFWDLSLPIAKRGYPEVTL 455
S FDPF LSLP+ Y ++ +
Sbjct: 698 SVRFDPFNFLSLPLPMDSYMDLEI 721
Score = 64.7 bits (156), Expect = 2e-10
Identities = 27/58 (46%), Positives = 38/58 (65%), Gaps = 1/58 (1%)
Query: 540 VYNLYAVSNHSGTTMGGHYTAYCRSPGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFYE 597
+YNLYA+S HSG GGHY Y ++P +W+ +NDSS + ++ T AY+LFYE
Sbjct: 1311 IYNLYAISCHSGILSGGHYITYAKNPNC-KWYCYNDSSCEELHPDEIDTDSAYILFYE 1367
Score = 47.8 bits (112), Expect = 3e-05
Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 3/70 (4%)
Query: 453 VTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRF---SESR 509
+ L C+R FT E+ L E C +C+ KK + R P L++HLKRF ++
Sbjct: 1031 INLDSCLRAFTSEEELGESEMYYCSKCKTHCLATKKLDLWRLPPFLIIHLKRFQFVNDQW 1090
Query: 510 IRTSKLTTFV 519
I++ K+ F+
Sbjct: 1091 IKSQKIVRFL 1100
>gi|41152235 ubiquitin specific protease 51 [Homo sapiens]
Length = 711
Score = 152 bits (384), Expect = 9e-37
Identities = 111/372 (29%), Positives = 168/372 (45%), Gaps = 69/372 (18%)
Query: 265 GLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHG--SNAHTALVEEFAKLI 322
GL GL NLGNTCFMN I+Q L++ L+D+ ++ D H ++ LV E + L
Sbjct: 361 GLRGLINLGNTCFMNCIVQALTHIPLLKDF-----FLSDKHKCIMTSPSLCLVCEMSSLF 415
Query: 323 QTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLRPKS 382
+++ S + P + I +A GY QQDA EFL +LD LH
Sbjct: 416 HAMYSGSRTPHI-PYKLLHLIWIHAEHLAGYRQQDAHEFLIAILDVLHR----------- 463
Query: 383 NPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLS 442
H DD G++ + I +F G L+S +TC C ST DP WD+S
Sbjct: 464 ------HSKDDSGGQEANNPNCC--NCIIDQIFTGGLQSDVTCQACHSVSTTIDPCWDIS 515
Query: 443 LPIAKR-----------------------GYPEVTLMDCMRLFTKEDVLDGDEKPTCCRC 479
L + G P +T DC++ FT+ + L K C C
Sbjct: 516 LDLPGSCATFDSQNPERADSTVSRDDHIPGIPSLT--DCLQWFTRPEHLGSSAKIKCNSC 573
Query: 480 RGRKRCIKKFSIQRFPKILVLHLKRFSESRIRTSKLTTFVNFPLRDLDLREFASEN---- 535
+ + K+ ++++ P + HLKRF + K+ TF++FPL +LD+ F +
Sbjct: 574 QSYQESTKQLTMKKLPIVACFHLKRFEHVGKQRRKINTFISFPL-ELDMTPFLASTKESR 632
Query: 536 -----------TNHAVYNLYAVSNHSGTTMGGHYTAYCRSPGTGEWHTFNDSSVTPMSSS 584
N Y+L+AV NH GT GHYT++ R +W + +D+ +T +
Sbjct: 633 MKEGQPPTDCVPNENKYSLFAVINHHGTLESGHYTSFIRQQ-KDQWFSCDDAIITKATIE 691
Query: 585 QVRTSDAYLLFY 596
+ S+ YLLFY
Sbjct: 692 DLLYSEGYLLFY 703
>gi|22550104 ubiquitin specific protease 32 [Homo sapiens]
Length = 1604
Score = 152 bits (384), Expect = 9e-37
Identities = 81/191 (42%), Positives = 114/191 (59%), Gaps = 7/191 (3%)
Query: 264 QGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHH----GSNAHTALVEEFA 319
+G GL NLGNTCFMNS +QC+SNT+ L Y + ++ +L+ G H A +
Sbjct: 731 KGATGLSNLGNTCFMNSSIQCVSNTQPLTQYFISGRHLYELNRTNPIGMKGHMAKC--YG 788
Query: 320 KLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLR 379
L+Q +W+ + +V +P + + I +YAPRF G+ QQD+QE L FLLDGLH ++NRV +
Sbjct: 789 DLVQELWSGTQKNV-APLKLRWTIAKYAPRFNGFQQQDSQELLAFLLDGLHEDLNRVHEK 847
Query: 380 PKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFW 439
P ++ D PD E + W +L R S + DLF GQL+S + C CG+ S FDPF
Sbjct: 848 PYVELKDSDGRPDWEVAAEAWDNHLRRNRSIVVDLFHGQLRSQVKCKTCGHISVRFDPFN 907
Query: 440 DLSLPIAKRGY 450
LSLP+ Y
Sbjct: 908 FLSLPLPMDSY 918
Score = 64.3 bits (155), Expect = 3e-10
Identities = 27/58 (46%), Positives = 38/58 (65%), Gaps = 1/58 (1%)
Query: 540 VYNLYAVSNHSGTTMGGHYTAYCRSPGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFYE 597
+YNLYA+S HSG GGHY Y ++P +W+ +NDSS + ++ T AY+LFYE
Sbjct: 1509 IYNLYAISCHSGILGGGHYVTYAKNPNC-KWYCYNDSSCKELHPDEIDTDSAYILFYE 1565
Score = 53.1 bits (126), Expect = 7e-07
Identities = 28/79 (35%), Positives = 37/79 (46%)
Query: 453 VTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRFSESRIRT 512
+ L C+R FT E+ L +E C +C+ KK + R P IL++HLKRF R
Sbjct: 1233 INLDSCLRAFTSEEELGENEMYYCSKCKTHCLATKKLDLWRLPPILIIHLKRFQFVNGRW 1292
Query: 513 SKLTTFVNFPLRDLDLREF 531
K V FP D F
Sbjct: 1293 IKSQKIVKFPRESFDPSAF 1311
>gi|57529246 ubiquitin thioesterase 19 [Homo sapiens]
Length = 1318
Score = 150 bits (379), Expect = 3e-36
Identities = 78/186 (41%), Positives = 111/186 (59%), Gaps = 3/186 (1%)
Query: 265 GLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTA--LVEEFAKLI 322
G GL NLGNTCFMNS++Q LSNTRELRD+ R + ++++ + T L FA L+
Sbjct: 495 GFTGLVNLGNTCFMNSVIQSLSNTRELRDFFHDRSFEAEINYNNPLGTGGRLAIGFAVLL 554
Query: 323 QTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLRPKS 382
+ +W + + PS+ K + A +F GY Q DAQEF+ FLLDGLH ++NR+ +P +
Sbjct: 555 RALWKGT-HHAFQPSKLKAIVASKASQFTGYAQHDAQEFMAFLLDGLHEDLNRIQNKPYT 613
Query: 383 NPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLS 442
+ D PD+ + W+++ R DS I DLF GQ KS L C C S FDPF L
Sbjct: 614 ETVDSDGRPDEVVAEEAWQRHKMRNDSFIVDLFQGQYKSKLVCPVCAKVSITFDPFLYLP 673
Query: 443 LPIAKR 448
+P+ ++
Sbjct: 674 VPLPQK 679
Score = 109 bits (272), Expect = 8e-24
Identities = 63/159 (39%), Positives = 87/159 (54%), Gaps = 10/159 (6%)
Query: 454 TLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRFS-ESRIRT 512
TL C+ LFT+ +VL +E C +C+ + K+ + R P +L++ LKRFS S I
Sbjct: 1059 TLDQCLNLFTRPEVLAPEEAWYCPQCKQHREASKQLLLWRLPNVLIVQLKRFSFRSFIWR 1118
Query: 513 SKLTTFVNFPLRDLDLREFASENTNHAV--YNLYAVSNHSGTTMGGHYTAYCRSPGTGE- 569
K+ V FP+R+LDL +F + Y+LYAV NH G +GGHYTA R P
Sbjct: 1119 DKINDLVEFPVRNLDLSKFCIGQKEEQLPSYDLYAVINHYGGMIGGHYTACARLPNDRSS 1178
Query: 570 ------WHTFNDSSVTPMSSSQVRTSDAYLLFYELASPP 602
W F+DS+VT + SQV T AY+LFY + P
Sbjct: 1179 QRSDVGWRLFDDSTVTTVDESQVVTRYAYVLFYRRRNSP 1217
>gi|42516561 ubiquitin specific protease 33 isoform 3 [Homo sapiens]
Length = 828
Score = 136 bits (343), Expect = 5e-32
Identities = 82/244 (33%), Positives = 123/244 (50%), Gaps = 44/244 (18%)
Query: 401 RKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLSLPI--------------- 445
+K ++ S I D+F G + SS+ C C S + F DLSLPI
Sbjct: 465 KKQHKKYRSVISDIFDGTIISSVQCLTCDRVSVTLETFQDLSLPIPGKEDLAKLHSSSHP 524
Query: 446 -------------AKRGY--------------PEVTLMDCMRLFTKEDVLDGDEKPTCCR 478
A +G+ P VTL DC+ F D L GD +C +
Sbjct: 525 TSIVKAGSCGEAYAPQGWIAFFMEYVKSWFWGPVVTLQDCLAAFFARDELKGDNMYSCEK 584
Query: 479 CRGRKRCIKKFSIQRFPKILVLHLKRFSESRIRTSKLTTFVNFPLRDLDLREFASENTNH 538
C+ + +K +Q FP+IL +HLKRF + ++K++T V+FPL LDL+ F ++++
Sbjct: 585 CKKLRNGVKFCKVQNFPEILCIHLKRFRHELMFSTKISTHVSFPLEGLDLQPFLAKDSPA 644
Query: 539 AV--YNLYAVSNHSGTTMGGHYTAYCRSPGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFY 596
+ Y+L +V H GT GHY AYCR+ W+ F+D SVT +S S V+ ++AY+LFY
Sbjct: 645 QIVTYDLLSVICHHGTASSGHYIAYCRNNLNNLWYEFDDQSVTEVSESTVQNAEAYVLFY 704
Query: 597 ELAS 600
+S
Sbjct: 705 RKSS 708
Score = 84.7 bits (208), Expect = 2e-16
Identities = 49/129 (37%), Positives = 70/129 (54%), Gaps = 12/129 (9%)
Query: 263 AQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHT----ALVEEF 318
A+GL GL+N+GNTC+MN+ LQ LSN L + L G A T A+ + +
Sbjct: 181 ARGLTGLKNIGNTCYMNAALQALSNCPPLTQFFLDC--------GGLARTDKKPAICKSY 232
Query: 319 AKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTL 378
KL+ +W S V P+ I+ P F GY+QQDAQEFLR L+D LH E+ +
Sbjct: 233 LKLMTELWHKSRPGSVVPTTLFQGIKTVNPTFRGYSQQDAQEFLRCLMDLLHEELKEQVM 292
Query: 379 RPKSNPENL 387
+ +P+ +
Sbjct: 293 EVEEDPQTI 301
>gi|42516567 ubiquitin specific protease 33 isoform 1 [Homo sapiens]
Length = 942
Score = 133 bits (335), Expect = 4e-31
Identities = 82/252 (32%), Positives = 123/252 (48%), Gaps = 52/252 (20%)
Query: 401 RKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLSLPI--------------- 445
+K ++ S I D+F G + SS+ C C S + F DLSLPI
Sbjct: 465 KKQHKKYRSVISDIFDGTIISSVQCLTCDRVSVTLETFQDLSLPIPGKEDLAKLHSSSHP 524
Query: 446 -------------AKRGY----------------------PEVTLMDCMRLFTKEDVLDG 470
A +G+ P VTL DC+ F D L G
Sbjct: 525 TSIVKAGSCGEAYAPQGWIAFFMEYVKRFVVSCVPSWFWGPVVTLQDCLAAFFARDELKG 584
Query: 471 DEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRFSESRIRTSKLTTFVNFPLRDLDLRE 530
D +C +C+ + +K +Q FP+IL +HLKRF + ++K++T V+FPL LDL+
Sbjct: 585 DNMYSCEKCKKLRNGVKFCKVQNFPEILCIHLKRFRHELMFSTKISTHVSFPLEGLDLQP 644
Query: 531 FASENTNHAV--YNLYAVSNHSGTTMGGHYTAYCRSPGTGEWHTFNDSSVTPMSSSQVRT 588
F ++++ + Y+L +V H GT GHY AYCR+ W+ F+D SVT +S S V+
Sbjct: 645 FLAKDSPAQIVTYDLLSVICHHGTASSGHYIAYCRNNLNNLWYEFDDQSVTEVSESTVQN 704
Query: 589 SDAYLLFYELAS 600
++AY+LFY +S
Sbjct: 705 AEAYVLFYRKSS 716
Score = 84.7 bits (208), Expect = 2e-16
Identities = 49/129 (37%), Positives = 70/129 (54%), Gaps = 12/129 (9%)
Query: 263 AQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHT----ALVEEF 318
A+GL GL+N+GNTC+MN+ LQ LSN L + L G A T A+ + +
Sbjct: 181 ARGLTGLKNIGNTCYMNAALQALSNCPPLTQFFLDC--------GGLARTDKKPAICKSY 232
Query: 319 AKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTL 378
KL+ +W S V P+ I+ P F GY+QQDAQEFLR L+D LH E+ +
Sbjct: 233 LKLMTELWHKSRPGSVVPTTLFQGIKTVNPTFRGYSQQDAQEFLRCLMDLLHEELKEQVM 292
Query: 379 RPKSNPENL 387
+ +P+ +
Sbjct: 293 EVEEDPQTI 301
>gi|42516565 ubiquitin specific protease 33 isoform 2 [Homo sapiens]
Length = 911
Score = 133 bits (335), Expect = 4e-31
Identities = 82/252 (32%), Positives = 123/252 (48%), Gaps = 52/252 (20%)
Query: 401 RKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLSLPI--------------- 445
+K ++ S I D+F G + SS+ C C S + F DLSLPI
Sbjct: 434 KKQHKKYRSVISDIFDGTIISSVQCLTCDRVSVTLETFQDLSLPIPGKEDLAKLHSSSHP 493
Query: 446 -------------AKRGY----------------------PEVTLMDCMRLFTKEDVLDG 470
A +G+ P VTL DC+ F D L G
Sbjct: 494 TSIVKAGSCGEAYAPQGWIAFFMEYVKRFVVSCVPSWFWGPVVTLQDCLAAFFARDELKG 553
Query: 471 DEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRFSESRIRTSKLTTFVNFPLRDLDLRE 530
D +C +C+ + +K +Q FP+IL +HLKRF + ++K++T V+FPL LDL+
Sbjct: 554 DNMYSCEKCKKLRNGVKFCKVQNFPEILCIHLKRFRHELMFSTKISTHVSFPLEGLDLQP 613
Query: 531 FASENTNHAV--YNLYAVSNHSGTTMGGHYTAYCRSPGTGEWHTFNDSSVTPMSSSQVRT 588
F ++++ + Y+L +V H GT GHY AYCR+ W+ F+D SVT +S S V+
Sbjct: 614 FLAKDSPAQIVTYDLLSVICHHGTASSGHYIAYCRNNLNNLWYEFDDQSVTEVSESTVQN 673
Query: 589 SDAYLLFYELAS 600
++AY+LFY +S
Sbjct: 674 AEAYVLFYRKSS 685
Score = 84.7 bits (208), Expect = 2e-16
Identities = 49/129 (37%), Positives = 70/129 (54%), Gaps = 12/129 (9%)
Query: 263 AQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHT----ALVEEF 318
A+GL GL+N+GNTC+MN+ LQ LSN L + L G A T A+ + +
Sbjct: 150 ARGLTGLKNIGNTCYMNAALQALSNCPPLTQFFLDC--------GGLARTDKKPAICKSY 201
Query: 319 AKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTL 378
KL+ +W S V P+ I+ P F GY+QQDAQEFLR L+D LH E+ +
Sbjct: 202 LKLMTELWHKSRPGSVVPTTLFQGIKTVNPTFRGYSQQDAQEFLRCLMDLLHEELKEQVM 261
Query: 379 RPKSNPENL 387
+ +P+ +
Sbjct: 262 EVEEDPQTI 270
>gi|169217654 PREDICTED: similar to deubiquitinating enzyme DUB1
[Homo sapiens]
Length = 530
Score = 130 bits (328), Expect = 3e-30
Identities = 97/332 (29%), Positives = 159/332 (47%), Gaps = 41/332 (12%)
Query: 267 AGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTALVEEFAKLIQTIW 326
AGL+N+GNTC++N+ LQCL+ T L +Y L R + + H ++ A + + +
Sbjct: 80 AGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQ--AHITRAL- 136
Query: 327 TSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLRPKSNPEN 386
+P V+ PS Q A F Q+DA EFL F +D +
Sbjct: 137 -HNPGHVIQPS------QALAAGFHRGKQEDAHEFLMFTVDAMKKAC------------- 176
Query: 387 LDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLSLPIA 446
LP ++ + ++ + I +F G +S + C C S FDP+ D++L I
Sbjct: 177 ---LPGHKQA-----DHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDI- 227
Query: 447 KRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRFS 506
++ + K + L+G+ C C R K ++ K+L+L LKRFS
Sbjct: 228 ---QAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFS 284
Query: 507 ESRIRTSKLTTFVNFPLRDLDLREFAS-ENTNHAVYNLYAVSNHSG-TTMGGHYTAYCRS 564
+ + +K+ V +P LD++ + S +NT VY LYAV H+G + GHY +Y ++
Sbjct: 285 D--VTGNKIAKNVQYP-ECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKA 341
Query: 565 PGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFY 596
G+W+ +D+ VT S + V + AY+LFY
Sbjct: 342 Q-EGQWYKMDDAEVTASSITSVLSQQAYVLFY 372
>gi|239758075 PREDICTED: similar to deubiquitinating enzyme DUB1
[Homo sapiens]
Length = 530
Score = 130 bits (327), Expect = 3e-30
Identities = 97/332 (29%), Positives = 158/332 (47%), Gaps = 41/332 (12%)
Query: 267 AGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTALVEEFAKLIQTIW 326
AGL+N+GNTC++N+ LQCL+ T L +Y L R + + H ++ A + + +
Sbjct: 80 AGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQ--AHITRAL- 136
Query: 327 TSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLRPKSNPEN 386
+P V+ PS Q A F Q+DA EFL F +D + +
Sbjct: 137 -HNPGHVIQPS------QALAAGFHRGKQEDAHEFLMFTVDAMKKAC-------LPGHKQ 182
Query: 387 LDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLSLPIA 446
+DH ++ + I +F G +S + C C S FDP+ D++L I
Sbjct: 183 VDH--------------HSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDI- 227
Query: 447 KRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRFS 506
++ + K + L+G+ C C R K ++ K+L+L LKRFS
Sbjct: 228 ---QAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFS 284
Query: 507 ESRIRTSKLTTFVNFPLRDLDLREFAS-ENTNHAVYNLYAVSNHSG-TTMGGHYTAYCRS 564
+ + +K+ V +P LD++ + S +NT VY LYAV H+G + GHY +Y ++
Sbjct: 285 D--VTGNKIAKNVQYP-ECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKA 341
Query: 565 PGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFY 596
G+W+ +D+ VT S + V + AY+LFY
Sbjct: 342 Q-EGQWYKMDDAEVTASSITSVLSQQAYVLFY 372
>gi|113415490 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
sapiens]
Length = 530
Score = 130 bits (327), Expect = 3e-30
Identities = 97/332 (29%), Positives = 158/332 (47%), Gaps = 41/332 (12%)
Query: 267 AGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTALVEEFAKLIQTIW 326
AGL+N+GNTC++N+ LQCL+ T L +Y L R + + H ++ A + + +
Sbjct: 80 AGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQ--AHITRAL- 136
Query: 327 TSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLRPKSNPEN 386
+P V+ PS Q A F Q+DA EFL F +D + +
Sbjct: 137 -HNPGHVIQPS------QALAAGFHRGKQEDAHEFLMFTVDAMKKAC-------LPGHKQ 182
Query: 387 LDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLSLPIA 446
+DH ++ + I +F G +S + C C S FDP+ D++L I
Sbjct: 183 VDH--------------HSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDI- 227
Query: 447 KRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRFS 506
++ + K + L+G+ C C R K ++ K+L+L LKRFS
Sbjct: 228 ---QAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFS 284
Query: 507 ESRIRTSKLTTFVNFPLRDLDLREFASE-NTNHAVYNLYAVSNHSG-TTMGGHYTAYCRS 564
+ + +K+ V +P LD++ + S+ NT VY LYAV H+G + GHY +Y ++
Sbjct: 285 D--VTGNKIAKNVQYP-ECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKA 341
Query: 565 PGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFY 596
G+W+ +D+ VT S + V + AY+LFY
Sbjct: 342 Q-EGQWYKMDDAEVTASSITSVLSQQAYVLFY 372
>gi|113415488 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
sapiens]
Length = 530
Score = 130 bits (327), Expect = 3e-30
Identities = 97/332 (29%), Positives = 158/332 (47%), Gaps = 41/332 (12%)
Query: 267 AGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTALVEEFAKLIQTIW 326
AGL+N+GNTC++N+ LQCL+ T L +Y L R + + H ++ A + + +
Sbjct: 80 AGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQ--AHITRAL- 136
Query: 327 TSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLRPKSNPEN 386
+P V+ PS Q A F Q+DA EFL F +D + +
Sbjct: 137 -HNPGHVIQPS------QALAAGFHRGKQEDAHEFLMFTVDAMKKAC-------LPGHKQ 182
Query: 387 LDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLSLPIA 446
+DH ++ + I +F G +S + C C S FDP+ D++L I
Sbjct: 183 VDH--------------HSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDI- 227
Query: 447 KRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRFS 506
++ + K + L+G+ C C R K ++ K+L+L LKRFS
Sbjct: 228 ---QAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFS 284
Query: 507 ESRIRTSKLTTFVNFPLRDLDLREFASE-NTNHAVYNLYAVSNHSG-TTMGGHYTAYCRS 564
+ + +K+ V +P LD++ + S+ NT VY LYAV H+G + GHY +Y ++
Sbjct: 285 D--VTGNKIAKNVQYP-ECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKA 341
Query: 565 PGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFY 596
G+W+ +D+ VT S + V + AY+LFY
Sbjct: 342 Q-EGQWYKMDDAEVTASSITSVLSQQAYVLFY 372
>gi|113415486 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
sapiens]
Length = 530
Score = 130 bits (327), Expect = 3e-30
Identities = 97/332 (29%), Positives = 158/332 (47%), Gaps = 41/332 (12%)
Query: 267 AGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTALVEEFAKLIQTIW 326
AGL+N+GNTC++N+ LQCL+ T L +Y L R + + H ++ A + + +
Sbjct: 80 AGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQ--AHITRAL- 136
Query: 327 TSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLRPKSNPEN 386
+P V+ PS Q A F Q+DA EFL F +D + +
Sbjct: 137 -HNPGHVIQPS------QALAAGFHRGKQEDAHEFLMFTVDAMKKAC-------LPGHKQ 182
Query: 387 LDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLSLPIA 446
+DH ++ + I +F G +S + C C S FDP+ D++L I
Sbjct: 183 VDH--------------HSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDI- 227
Query: 447 KRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRFS 506
++ + K + L+G+ C C R K ++ K+L+L LKRFS
Sbjct: 228 ---QAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFS 284
Query: 507 ESRIRTSKLTTFVNFPLRDLDLREFASE-NTNHAVYNLYAVSNHSG-TTMGGHYTAYCRS 564
+ + +K+ V +P LD++ + S+ NT VY LYAV H+G + GHY +Y ++
Sbjct: 285 D--VTGNKIAKNVQYP-ECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKA 341
Query: 565 PGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFY 596
G+W+ +D+ VT S + V + AY+LFY
Sbjct: 342 Q-EGQWYKMDDAEVTASSITSVLSQQAYVLFY 372
>gi|113415484 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
sapiens]
Length = 530
Score = 130 bits (327), Expect = 3e-30
Identities = 97/332 (29%), Positives = 158/332 (47%), Gaps = 41/332 (12%)
Query: 267 AGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTALVEEFAKLIQTIW 326
AGL+N+GNTC++N+ LQCL+ T L +Y L R + + H ++ A + + +
Sbjct: 80 AGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQ--AHITRAL- 136
Query: 327 TSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLRPKSNPEN 386
+P V+ PS Q A F Q+DA EFL F +D + +
Sbjct: 137 -HNPGHVIQPS------QALAAGFHRGKQEDAHEFLMFTVDAMKKAC-------LPGHKQ 182
Query: 387 LDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLSLPIA 446
+DH ++ + I +F G +S + C C S FDP+ D++L I
Sbjct: 183 VDH--------------HSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDI- 227
Query: 447 KRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRFS 506
++ + K + L+G+ C C R K ++ K+L+L LKRFS
Sbjct: 228 ---QAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFS 284
Query: 507 ESRIRTSKLTTFVNFPLRDLDLREFASE-NTNHAVYNLYAVSNHSG-TTMGGHYTAYCRS 564
+ + +K+ V +P LD++ + S+ NT VY LYAV H+G + GHY +Y ++
Sbjct: 285 D--VTGNKIAKNVQYP-ECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKA 341
Query: 565 PGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFY 596
G+W+ +D+ VT S + V + AY+LFY
Sbjct: 342 Q-EGQWYKMDDAEVTASSITSVLSQQAYVLFY 372
>gi|113415482 PREDICTED: Ubiquitin carboxyl-terminal hydrolase
17-like protein 5 [Homo sapiens]
Length = 530
Score = 130 bits (327), Expect = 3e-30
Identities = 97/332 (29%), Positives = 158/332 (47%), Gaps = 41/332 (12%)
Query: 267 AGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTALVEEFAKLIQTIW 326
AGL+N+GNTC++N+ LQCL+ T L +Y L R + + H ++ A + + +
Sbjct: 80 AGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQ--AHITRAL- 136
Query: 327 TSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLRPKSNPEN 386
+P V+ PS Q A F Q+DA EFL F +D + +
Sbjct: 137 -HNPGHVIQPS------QALAAGFHRGKQEDAHEFLMFTVDAMKKAC-------LPGHKQ 182
Query: 387 LDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLSLPIA 446
+DH ++ + I +F G +S + C C S FDP+ D++L I
Sbjct: 183 VDH--------------HSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDI- 227
Query: 447 KRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRFS 506
++ + K + L+G+ C C R K ++ K+L+L LKRFS
Sbjct: 228 ---QAAQSVQQALEQLAKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFS 284
Query: 507 ESRIRTSKLTTFVNFPLRDLDLREFASE-NTNHAVYNLYAVSNHSG-TTMGGHYTAYCRS 564
+ + +K+ V +P LD++ + S+ NT VY LYAV H+G + GHY +Y ++
Sbjct: 285 D--VTGNKIAKNVQYP-ECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKA 341
Query: 565 PGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFY 596
G+W+ +D+ VT S + V + AY+LFY
Sbjct: 342 Q-EGQWYKMDDAEVTASSITSVLSQQAYVLFY 372
>gi|113415480 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
sapiens]
Length = 530
Score = 130 bits (327), Expect = 3e-30
Identities = 97/332 (29%), Positives = 158/332 (47%), Gaps = 41/332 (12%)
Query: 267 AGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTALVEEFAKLIQTIW 326
AGL+N+GNTC++N+ LQCL+ T L +Y L R + + H ++ A + + +
Sbjct: 80 AGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQ--AHITRAL- 136
Query: 327 TSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLRPKSNPEN 386
+P V+ PS Q A F Q+DA EFL F +D + +
Sbjct: 137 -HNPGHVIQPS------QALAAGFHRGKQEDAHEFLMFTVDAMKKAC-------LPGHKQ 182
Query: 387 LDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLSLPIA 446
+DH ++ + I +F G +S + C C S FDP+ D++L I
Sbjct: 183 VDH--------------HSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDI- 227
Query: 447 KRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRFS 506
++ + K + L+G+ C C R K ++ K+L+L LKRFS
Sbjct: 228 ---QAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFS 284
Query: 507 ESRIRTSKLTTFVNFPLRDLDLREFASE-NTNHAVYNLYAVSNHSG-TTMGGHYTAYCRS 564
+ + +K+ V +P LD++ + S+ NT VY LYAV H+G + GHY +Y ++
Sbjct: 285 D--VTGNKIAKNVQYP-ECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKA 341
Query: 565 PGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFY 596
G+W+ +D+ VT S + V + AY+LFY
Sbjct: 342 Q-EGQWYKMDDAEVTASSITSVLSQQAYVLFY 372
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,868,934
Number of Sequences: 37866
Number of extensions: 1226564
Number of successful extensions: 4047
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 109
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 3567
Number of HSP's gapped (non-prelim): 208
length of query: 605
length of database: 18,247,518
effective HSP length: 108
effective length of query: 497
effective length of database: 14,157,990
effective search space: 7036521030
effective search space used: 7036521030
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.