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Search of human proteins with 188528609
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|188528609 secreted frizzled-related protein 5 [Homo sapiens]
(317 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|188528609 secreted frizzled-related protein 5 [Homo sapiens] 671 0.0
gi|56117838 secreted frizzled-related protein 1 [Homo sapiens] 356 2e-98
gi|48475052 secreted frizzled-related protein 2 precursor [Homo ... 238 7e-63
gi|4503833 frizzled 7 [Homo sapiens] 110 1e-24
gi|4503835 frizzled 9 [Homo sapiens] 107 2e-23
gi|27894385 frizzled 5 precursor [Homo sapiens] 105 4e-23
gi|6005762 frizzled 10 [Homo sapiens] 105 4e-23
gi|4503825 frizzled 1 [Homo sapiens] 103 2e-22
gi|13994190 frizzled 8 [Homo sapiens] 103 3e-22
gi|4503827 frizzled 2 [Homo sapiens] 102 4e-22
gi|22547161 frizzled 4 [Homo sapiens] 99 4e-21
gi|38455388 frizzled-related protein [Homo sapiens] 96 4e-20
gi|8393378 frizzled 3 [Homo sapiens] 83 3e-16
gi|170784838 secreted frizzled-related protein 4 [Homo sapiens] 80 3e-15
gi|34734079 frizzled 6 [Homo sapiens] 75 1e-13
gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens] 67 2e-11
gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens] 66 5e-11
gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Ho... 64 1e-10
gi|29244926 corin [Homo sapiens] 61 1e-09
gi|13899255 membrane frizzled-related protein [Homo sapiens] 53 4e-07
gi|5032099 smoothened [Homo sapiens] 44 1e-04
gi|16751923 WAP, follistatin/kazal, immunoglobulin, kunitz and n... 37 0.018
gi|28212222 WFIKKN2 protein [Homo sapiens] 33 0.25
gi|38016904 thrombospondin repeat containing 1 isoform 1 [Homo s... 31 1.3
gi|153792694 baculoviral IAP repeat-containing 6 [Homo sapiens] 31 1.3
gi|56788359 thrombospondin repeat containing 1 isoform 2 [Homo s... 31 1.3
gi|67782358 complement factor B preproprotein [Homo sapiens] 31 1.7
gi|12232389 methyltransferase 11 domain containing 1 isoform 2 [... 30 2.8
gi|71999135 methyltransferase 11 domain containing 1 isoform 1 [... 30 2.8
gi|124517699 ankyrin repeat domain 13B [Homo sapiens] 30 3.7
>gi|188528609 secreted frizzled-related protein 5 [Homo sapiens]
Length = 317
Score = 671 bits (1732), Expect = 0.0
Identities = 317/317 (100%), Positives = 317/317 (100%)
Query: 1 MRAAAAGGGVRTAALALLLGALHWAPARCEEYDYYGWQAEPLHGRSYSKPPQCLDIPADL 60
MRAAAAGGGVRTAALALLLGALHWAPARCEEYDYYGWQAEPLHGRSYSKPPQCLDIPADL
Sbjct: 1 MRAAAAGGGVRTAALALLLGALHWAPARCEEYDYYGWQAEPLHGRSYSKPPQCLDIPADL 60
Query: 61 PLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDTQVFLCSLFAPVCLDRP 120
PLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDTQVFLCSLFAPVCLDRP
Sbjct: 61 PLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDTQVFLCSLFAPVCLDRP 120
Query: 121 IYPCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHKFPLDNDLCIAVQFGHLPATAPPVTKI 180
IYPCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHKFPLDNDLCIAVQFGHLPATAPPVTKI
Sbjct: 121 IYPCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHKFPLDNDLCIAVQFGHLPATAPPVTKI 180
Query: 181 CAQCEMEHSADGLMEQMCSSDFVVKMRIKEIKIENGDRKLIGAQKKKKLLKPGPLKRKDT 240
CAQCEMEHSADGLMEQMCSSDFVVKMRIKEIKIENGDRKLIGAQKKKKLLKPGPLKRKDT
Sbjct: 181 CAQCEMEHSADGLMEQMCSSDFVVKMRIKEIKIENGDRKLIGAQKKKKLLKPGPLKRKDT 240
Query: 241 KRLVLHMKNGAGCPCPQLDSLAGSFLVMGRKVDGQLLLMAVYRWDKKNKEMKFAVKFMFS 300
KRLVLHMKNGAGCPCPQLDSLAGSFLVMGRKVDGQLLLMAVYRWDKKNKEMKFAVKFMFS
Sbjct: 241 KRLVLHMKNGAGCPCPQLDSLAGSFLVMGRKVDGQLLLMAVYRWDKKNKEMKFAVKFMFS 300
Query: 301 YPCSLYYPFFYGAAEPH 317
YPCSLYYPFFYGAAEPH
Sbjct: 301 YPCSLYYPFFYGAAEPH 317
>gi|56117838 secreted frizzled-related protein 1 [Homo sapiens]
Length = 314
Score = 356 bits (913), Expect = 2e-98
Identities = 178/309 (57%), Positives = 228/309 (73%), Gaps = 9/309 (2%)
Query: 8 GGVRTAALALLL--GALHWAPARCEEYDYYGWQAE--PLH-GRSYSKPPQCLDIPADLPL 62
GG R AAL +LL GA A EYDY +Q++ P GR Y+KPPQC+DIPADL L
Sbjct: 8 GGRRGAALGVLLALGAALLAVGSASEYDYVSFQSDIGPYQSGRFYTKPPQCVDIPADLRL 67
Query: 63 CHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDTQVFLCSLFAPVCLDRPIY 122
CH VGYK+M LPNLLEHE++AEVKQQASSW+PLL K CH+ TQVFLCSLFAPVCLDRPIY
Sbjct: 68 CHNVGYKKMVLPNLLEHETMAEVKQQASSWVPLLNKNCHAGTQVFLCSLFAPVCLDRPIY 127
Query: 123 PCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHKFPLDNDLCIAVQFGH-LPATAPPVTKIC 181
PCR LCEAVR C P+M+ +GF WPEML C KFP + D+CIA+ + A+ P T +C
Sbjct: 128 PCRWLCEAVRDSCEPVMQFFGFYWPEMLKCDKFP-EGDVCIAMTPPNATEASKPQGTTVC 186
Query: 182 AQCEMEHSADGLMEQMCSSDFVVKMRIKEIKIENGDRKLIGAQKKKKLLKPGPLKRKDTK 241
C+ E ++ ++E +C+S+F ++M+IKE+K ENGD+K++ KKKK LK GP+K+KD K
Sbjct: 187 PPCDNELKSEAIIEHLCASEFALRMKIKEVKKENGDKKIV--PKKKKPLKLGPIKKKDLK 244
Query: 242 RLVLHMKNGAGCPCPQLDSLAGSFLVMGRKVDGQLLLMAVYRWDKKNKEMKFAVKFMFSY 301
+LVL++KNGA CPC QLD+L+ FL+MGRKV Q LL A+++WDKKNKE K +K M ++
Sbjct: 245 KLVLYLKNGADCPCHQLDNLSHHFLIMGRKVKSQYLLTAIHKWDKKNKEFKNFMKKMKNH 304
Query: 302 PCSLYYPFF 310
C + F
Sbjct: 305 ECPTFQSVF 313
>gi|48475052 secreted frizzled-related protein 2 precursor [Homo
sapiens]
Length = 295
Score = 238 bits (606), Expect = 7e-63
Identities = 113/249 (45%), Positives = 159/249 (63%), Gaps = 5/249 (2%)
Query: 49 KPPQCLDIPADLPLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDTQVFL 108
K C IPA+L LCH + Y+ MRLPNLL HE++ EV +QA +W+PL+ K+CH DT+ FL
Sbjct: 36 KRSNCKPIPANLQLCHGIEYQNMRLPNLLGHETMKEVLEQAGAWIPLVMKQCHPDTKKFL 95
Query: 109 CSLFAPVC---LDRPIYPCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHKFPLDNDLCIAV 165
CSLFAPVC LD I PC SLC V+ CAP+M A+GFPWP+ML C +FP DNDLCI +
Sbjct: 96 CSLFAPVCLDDLDETIQPCHSLCVQVKDRCAPVMSAFGFPWPDMLECDRFPQDNDLCIPL 155
Query: 166 -QFGHLPATAPPVTKICAQCEMEHSADG-LMEQMCSSDFVVKMRIKEIKIENGDRKLIGA 223
HL K+C C+ ++ D +ME +C +DF +K+++KEI N D K+I
Sbjct: 156 ASSDHLLPATEEAPKVCEACKNKNDDDNDIMETLCKNDFALKIKVKEITYINRDTKIILE 215
Query: 224 QKKKKLLKPGPLKRKDTKRLVLHMKNGAGCPCPQLDSLAGSFLVMGRKVDGQLLLMAVYR 283
K K + K + +D K+ VL +K+ C C +++ + +LVMG+K G+L++ +V R
Sbjct: 216 TKSKTIYKLNGVSERDLKKSVLWLKDSLQCTCEEMNDINAPYLVMGQKQGGELVITSVKR 275
Query: 284 WDKKNKEMK 292
W K +E K
Sbjct: 276 WQKGQREFK 284
>gi|4503833 frizzled 7 [Homo sapiens]
Length = 574
Score = 110 bits (276), Expect = 1e-24
Identities = 65/167 (38%), Positives = 87/167 (52%), Gaps = 17/167 (10%)
Query: 3 AAAAGGGVRTAALAL-LLGALHWAPARCEEYDYYGWQAEPLHG-RSYSKPPQCLDIPADL 60
AAA + AL L LLGAL G A+P HG + S P P +
Sbjct: 6 AAAPLSSLGLCALVLALLGALS-----------AGAGAQPYHGEKGISVPDHGFCQPISI 54
Query: 61 PLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDTQVFLCSLFAPVC--LD 118
PLC + Y + LPNLL H + + + + PL+ +C + + FLCS++APVC LD
Sbjct: 55 PLCTDIAYNQTILPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLD 114
Query: 119 RPIYPCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHKFPLD--NDLCI 163
+ I PCRSLCE R GC LM +GF WPE L C FP+ ++C+
Sbjct: 115 QAIPPCRSLCERARQGCEALMNKFGFQWPERLRCENFPVHGAGEICV 161
>gi|4503835 frizzled 9 [Homo sapiens]
Length = 591
Score = 107 bits (266), Expect = 2e-23
Identities = 52/124 (41%), Positives = 72/124 (58%), Gaps = 8/124 (6%)
Query: 40 EPLHGRSYSKPPQCLDIPADLPLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKR 99
+P GR + P Q ++IP +C +GY R+PNLL H S E + + + PL+
Sbjct: 29 DPERGRG-AAPCQAVEIP----MCRGIGYNLTRMPNLLGHTSQGEAAAELAEFAPLVQYG 83
Query: 100 CHSDTQVFLCSLFAPVCLDR---PIYPCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHKFP 156
CHS + FLCSL+AP+C D+ PI CR +CE R CAP+ME + F WP+ L C + P
Sbjct: 84 CHSHLRFFLCSLYAPMCTDQVSTPIPACRPMCEQARLRCAPIMEQFNFGWPDSLDCARLP 143
Query: 157 LDND 160
ND
Sbjct: 144 TRND 147
>gi|27894385 frizzled 5 precursor [Homo sapiens]
Length = 585
Score = 105 bits (263), Expect = 4e-23
Identities = 45/113 (39%), Positives = 68/113 (60%), Gaps = 5/113 (4%)
Query: 48 SKPPQCLDIPADLPLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDTQVF 107
SK P C +I +P+C +GY +PN H++ E + + PL+ +C D + F
Sbjct: 28 SKAPVCQEIT--VPMCRGIGYNLTHMPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLRFF 85
Query: 108 LCSLFAPVCLD---RPIYPCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHKFPL 157
LCS++ P+CL +P+ PCRS+CE +AGC+PLM YGF WPE + C + P+
Sbjct: 86 LCSMYTPICLPDYHKPLPPCRSVCERAKAGCSPLMRQYGFAWPERMSCDRLPV 138
>gi|6005762 frizzled 10 [Homo sapiens]
Length = 581
Score = 105 bits (263), Expect = 4e-23
Identities = 45/107 (42%), Positives = 64/107 (59%), Gaps = 3/107 (2%)
Query: 57 PADLPLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDTQVFLCSLFAPVC 116
P ++P+C +GY R+PNL+ HE+ E Q + PL+ CH + FLCSL+AP+C
Sbjct: 36 PIEIPMCKDIGYNMTRMPNLMGHENQREAAIQLHEFAPLVEYGCHGHLRFFLCSLYAPMC 95
Query: 117 LDR---PIYPCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHKFPLDND 160
++ PI CR +CE R C+P+ME + F WP+ L C K P ND
Sbjct: 96 TEQVSTPIPACRVMCEQARLKCSPIMEQFNFKWPDSLDCRKLPNKND 142
>gi|4503825 frizzled 1 [Homo sapiens]
Length = 647
Score = 103 bits (258), Expect = 2e-22
Identities = 48/123 (39%), Positives = 71/123 (57%), Gaps = 4/123 (3%)
Query: 45 RSYSKPPQCLDIPADLPLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDT 104
R S P P +PLC + Y + +PNLL H + + + + PL+ +C ++
Sbjct: 106 RGISVPDHGYCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSAEL 165
Query: 105 QVFLCSLFAPVC--LDRPIYPCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHKFPLD--ND 160
+ FLCS++APVC L++ + PCRSLCE R GC LM +GF WP+ L C KFP+ +
Sbjct: 166 KFFLCSMYAPVCTVLEQALPPCRSLCERARQGCEALMNKFGFQWPDTLKCEKFPVHGAGE 225
Query: 161 LCI 163
LC+
Sbjct: 226 LCV 228
>gi|13994190 frizzled 8 [Homo sapiens]
Length = 694
Score = 103 bits (256), Expect = 3e-22
Identities = 46/122 (37%), Positives = 69/122 (56%), Gaps = 6/122 (4%)
Query: 60 LPLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDTQVFLCSLFAPVCLD- 118
+PLC +GY +PN H++ E + + PL+ +C D + FLCS++ P+CL+
Sbjct: 40 VPLCKGIGYNYTYMPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLKFFLCSMYTPICLED 99
Query: 119 --RPIYPCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHKFPLDND---LCIAVQFGHLPAT 173
+P+ PCRS+CE +AGCAPLM YGF WP+ + C + P + LC+ L
Sbjct: 100 YKKPLPPCRSVCERAKAGCAPLMRQYGFAWPDRMRCDRLPEQGNPDTLCMDYNRTDLTTA 159
Query: 174 AP 175
AP
Sbjct: 160 AP 161
>gi|4503827 frizzled 2 [Homo sapiens]
Length = 565
Score = 102 bits (254), Expect = 4e-22
Identities = 55/144 (38%), Positives = 74/144 (51%), Gaps = 10/144 (6%)
Query: 43 HG-RSYSKPPQCLDIPADLPLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCH 101
HG + S P P +PLC + Y + +PNLL H + + + + PL+ +C
Sbjct: 26 HGEKGISIPDHGFCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCS 85
Query: 102 SDTQVFLCSLFAPVC--LDRPIYPCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHKFPLDN 159
+ + FLCS++APVC L++ I PCRS+CE R GC LM +GF WPE L C FP
Sbjct: 86 PELRFFLCSMYAPVCTVLEQAIPPCRSICERARQGCEALMNKFGFQWPERLRCEHFPRHG 145
Query: 160 DLCIAVQFGH-------LPATAPP 176
I V H L TAPP
Sbjct: 146 AEQICVGQNHSEDGAPALLTTAPP 169
>gi|22547161 frizzled 4 [Homo sapiens]
Length = 537
Score = 99.4 bits (246), Expect = 4e-21
Identities = 41/107 (38%), Positives = 66/107 (61%), Gaps = 3/107 (2%)
Query: 57 PADLPLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDTQVFLCSLFAPVC 116
P + +C +GY ++PNL+ HE + + Q +++ PL+ C S Q FLCS++ P+C
Sbjct: 47 PIRISMCQNLGYNVTKMPNLVGHELQTDAELQLTTFTPLIQYGCSSQLQFFLCSVYVPMC 106
Query: 117 LDR---PIYPCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHKFPLDND 160
++ PI PC +C +V+ C P+++ +GF WPE L+C KFP ND
Sbjct: 107 TEKINIPIGPCGGMCLSVKRRCEPVLKEFGFAWPESLNCSKFPPQND 153
>gi|38455388 frizzled-related protein [Homo sapiens]
Length = 325
Score = 95.9 bits (237), Expect = 4e-20
Identities = 70/265 (26%), Positives = 124/265 (46%), Gaps = 43/265 (16%)
Query: 57 PADLPLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDTQVFLCSLFAPVC 116
P +PLC ++ + ++PN L H + A + LL C D FLC+++AP+C
Sbjct: 37 PVRIPLCKSLPWNMTKMPNHLHHSTQANAILAIEQFEGLLGTHCSPDLLFFLCAMYAPIC 96
Query: 117 L----DRPIYPCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHKFPL-DNDLCIAVQFGHLP 171
PI PC+S+CE R GC P++ Y WPE L C + P+ D +CI+ +
Sbjct: 97 TIDFQHEPIKPCKSVCERARQGCEPILIKYRHSWPENLACEELPVYDRGVCISPE----- 151
Query: 172 ATAPPVTKICAQCEMEHS---ADGLMEQMC---------------SSDFVVKMRIKEIKI 213
VT A M+ S G + C + ++V++ ++KEIK
Sbjct: 152 ---AIVTADGADFPMDSSNGNCRGASSERCKCKPIRATQKTYFRNNYNYVIRAKVKEIKT 208
Query: 214 ENGDRKLIGAQKKKKLLKPGPLKRKDTKRLVLHMKNGAGCPCPQLDSLAGSFLVMGRKVD 273
+ D + + K++LK + + R +++ +GC CP L ++ +++MG + +
Sbjct: 209 KCHD--VTAVVEVKEILKSSLV---NIPRDTVNLYTSSGCLCPPL-NVNEEYIIMGYEDE 262
Query: 274 GQLLLMAV-----YRW-DKKNKEMK 292
+ L+ V +W D+ K++K
Sbjct: 263 ERSRLLLVEGSIAEKWKDRLGKKVK 287
>gi|8393378 frizzled 3 [Homo sapiens]
Length = 666
Score = 83.2 bits (204), Expect = 3e-16
Identities = 37/102 (36%), Positives = 55/102 (53%), Gaps = 2/102 (1%)
Query: 57 PADLPLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDTQVFLCSLFAPVC 116
P L +C + Y +PNLL H + P++ C D + FLC+L+AP+C
Sbjct: 30 PITLRMCQDLPYNTTFMPNLLNHYDQQTAALAMEPFHPMVNLDCSRDFRPFLCALYAPIC 89
Query: 117 LD--RPIYPCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHKFP 156
++ R PCR LC+ + C+ LME +G PWPE + C +FP
Sbjct: 90 MEYGRVTLPCRRLCQRAYSECSKLMEMFGVPWPEDMECSRFP 131
>gi|170784838 secreted frizzled-related protein 4 [Homo sapiens]
Length = 346
Score = 79.7 bits (195), Expect = 3e-15
Identities = 37/110 (33%), Positives = 59/110 (53%), Gaps = 5/110 (4%)
Query: 60 LPLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDTQVFLCSLFAPVC--- 116
+P+C + + R+PN L H + + L+ C + + FLC+++AP+C
Sbjct: 29 IPMCRHMPWNITRMPNHLHHSTQENAILAIEQYEELVDVNCSAVLRFFLCAMYAPICTLE 88
Query: 117 -LDRPIYPCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHKFPL-DNDLCIA 164
L PI PC+S+C+ R C PLM+ Y WPE L C + P+ D +CI+
Sbjct: 89 FLHDPIKPCKSVCQRARDDCEPLMKMYNHSWPESLACDELPVYDRGVCIS 138
>gi|34734079 frizzled 6 [Homo sapiens]
Length = 706
Score = 74.7 bits (182), Expect = 1e-13
Identities = 33/100 (33%), Positives = 50/100 (50%), Gaps = 2/100 (2%)
Query: 57 PADLPLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDTQVFLCSLFAPVC 116
P +P C + Y PNL+ H + + +LPL C + + FLC F P C
Sbjct: 26 PITVPRCMKMAYNMTFFPNLMGHYDQSIAAVEMEHFLPLANLECSPNIETFLCKAFVPTC 85
Query: 117 LDR--PIYPCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHK 154
+++ + PCR LCE V + C L++ +G WPE L C +
Sbjct: 86 IEQIHVVPPCRKLCEKVYSDCKKLIDTFGIRWPEELECDR 125
>gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens]
Length = 641
Score = 67.4 bits (163), Expect = 2e-11
Identities = 36/119 (30%), Positives = 56/119 (47%), Gaps = 8/119 (6%)
Query: 44 GRSYSKPPQCLDIPADLPLCHTVGYKRMRLPNLLEHESLAEVKQQASSWL------PLLA 97
G + + P + L C Y PNLL+H S EV + +S ++ LL
Sbjct: 21 GCEFERNPAATCVDLQLRTCSDAAYNHTTFPNLLQHRSW-EVVEASSEYILLSVLHQLLE 79
Query: 98 KRCHSDTQVFLCSLFAPVCLDRPIY-PCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHKF 155
+C+ D ++ C++ AP C + PCR +CE +R C P +A WP L CH++
Sbjct: 80 GQCNPDLRLLGCAVLAPRCEGGWVRRPCRHICEGLREVCQPAFDAIDMAWPYFLDCHRY 138
>gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens]
Length = 652
Score = 65.9 bits (159), Expect = 5e-11
Identities = 36/110 (32%), Positives = 55/110 (50%), Gaps = 10/110 (9%)
Query: 53 CLDIPADLPLCHTVGYKRMRLPNLLEHESLAEVKQQASSWL------PLLAKRCHSDTQV 106
C+D+ L C Y PNLL+H S EV + +S ++ LL +C+ D ++
Sbjct: 43 CVDL--QLRTCSDAAYNHTTFPNLLQHRSW-EVVEASSEYILLSVLHQLLEGQCNPDLRL 99
Query: 107 FLCSLFAPVCLDRPIY-PCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHKF 155
C++ AP C + PCR +CE +R C P +A WP L CH++
Sbjct: 100 LGCAVLAPRCEGGWVRRPCRHICEGLREVCQPAFDAIDMAWPYFLDCHRY 149
>gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Homo
sapiens]
Length = 1751
Score = 64.3 bits (155), Expect = 1e-10
Identities = 34/87 (39%), Positives = 43/87 (49%), Gaps = 3/87 (3%)
Query: 52 QCLDIPADLPLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDTQVFLCSL 111
+CL +P LP+C +G R LPN L HES +V+ A +W LL CH F C L
Sbjct: 333 RCLPLPPSLPVCGHLGISRFWLPNHLHHESGEQVRAGARAWGGLLQTHCHPFLAWFFCLL 392
Query: 112 FAPVCLDRP---IYPCRSLCEAVRAGC 135
P C P PC CEA++ C
Sbjct: 393 LVPPCGSVPPPAPPPCCQFCEALQDAC 419
>gi|29244926 corin [Homo sapiens]
Length = 1042
Score = 60.8 bits (146), Expect = 1e-09
Identities = 34/115 (29%), Positives = 50/115 (43%), Gaps = 8/115 (6%)
Query: 57 PADLPLCHTVGYKRMRLPNLLEHESLAE--VKQQASSWLPLLAKRCHSDTQVFLCSLFAP 114
P L LC + Y PN H + E + ++S + L+ C+ F C++ P
Sbjct: 457 PITLELCMNLPYNSTSYPNYFGHRTQKEASISWESSLFPALVQTNCYKYLMFFSCTILVP 516
Query: 115 VC---LDRPIYPCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHKFP---LDNDLCI 163
C I PCR+LCE + C ++ G WPE C +FP DN C+
Sbjct: 517 KCDVNTGEHIPPCRALCEHSKERCESVLGIVGLQWPEDTDCSQFPEENSDNQTCL 571
Score = 50.1 bits (118), Expect = 3e-06
Identities = 20/61 (32%), Positives = 31/61 (50%), Gaps = 5/61 (8%)
Query: 100 CHSDTQVFLCSLFAPVCL-----DRPIYPCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHK 154
C+ +F C+L P C+ + PCRS CEA + GC ++ + WP+ L C +
Sbjct: 183 CYQHIMLFGCTLAFPECIIDGDDSHGLLPCRSFCEAAKEGCESVLGMVNYSWPDFLRCSQ 242
Query: 155 F 155
F
Sbjct: 243 F 243
>gi|13899255 membrane frizzled-related protein [Homo sapiens]
Length = 579
Score = 52.8 bits (125), Expect = 4e-07
Identities = 33/118 (27%), Positives = 51/118 (43%), Gaps = 11/118 (9%)
Query: 50 PPQCLDIPADLPLCHTVGYKRMRLPNL----LEHESLAEVKQQASSWLPLLAKRCHSDTQ 105
PP+ P + +C + Y PN+ + E + EV S + L + C+ +
Sbjct: 461 PPELACEPVQVEMCLGLSYNTTAFPNIWVGMITQEEVVEV---LSGYKSLTSLPCYQHFR 517
Query: 106 VFLCSLFAPVC--LDRPIYPCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHKFPLDNDL 161
LC L P C L + PCRS+C+ C + G PWP +C++ P DL
Sbjct: 518 RLLCGLLVPRCTPLGSVLPPCRSVCQEAEHQCQSGLALLGTPWP--FNCNRLPEAADL 573
>gi|5032099 smoothened [Homo sapiens]
Length = 787
Score = 44.3 bits (103), Expect = 1e-04
Identities = 25/63 (39%), Positives = 34/63 (53%), Gaps = 5/63 (7%)
Query: 97 AKRCHSDTQVFLCSLFAPVCL-DRPIYPCRSLCEAVRAGCAPLMEAYGFPWPEMLHC--H 153
A RC + Q LC+++ P C DR P R+LC+A R CA + G WP+ L C
Sbjct: 115 APRCWAVIQPLLCAVYMPKCENDRVELPSRTLCQATRGPCAIVERERG--WPDFLRCTPD 172
Query: 154 KFP 156
+FP
Sbjct: 173 RFP 175
>gi|16751923 WAP, follistatin/kazal, immunoglobulin, kunitz and
netrin domain containing 1 precursor [Homo sapiens]
Length = 548
Score = 37.4 bits (85), Expect = 0.018
Identities = 37/138 (26%), Positives = 55/138 (39%), Gaps = 7/138 (5%)
Query: 176 PVTKICAQCEMEHSADGLMEQMCSSDFVVKMRIKEIKIENGDRKLIGAQKKKKLLKPGP- 234
P T C C + L +C SDF + R+ E+ E I + +LK
Sbjct: 412 PRTPPCRACRLRSK---LALSLCRSDFAIVGRLTEVLEEPEAAGGIARVALEDVLKDDKM 468
Query: 235 -LKRKDTKRLVLHMKN-GAGCPCPQLDSLAGSFLVMGRKVDGQLLLMA-VYRWDKKNKEM 291
LK TK L + + CPCP + + G ++MG DG +L A Y K +
Sbjct: 469 GLKFLGTKYLEVTLSGMDWACPCPNMTAGDGPLVIMGEVRDGVAVLDAGSYVRAASEKRV 528
Query: 292 KFAVKFMFSYPCSLYYPF 309
K ++ + C L F
Sbjct: 529 KKILELLEKQACELLNRF 546
>gi|28212222 WFIKKN2 protein [Homo sapiens]
Length = 576
Score = 33.5 bits (75), Expect = 0.25
Identities = 28/102 (27%), Positives = 48/102 (47%), Gaps = 9/102 (8%)
Query: 181 CAQCEMEHSADGLMEQMCSSDFVVKMRIKEIKIE-NGDRKLIGAQKKKKLLKPGP--LKR 237
C C+ L+ C SDFV+ R+ E+ E + R L+ + K K G L +
Sbjct: 445 CRACKPRQK---LVTSFCRSDFVILGRVSELTEEPDSGRALVTVDEVLKDEKMGLKFLGQ 501
Query: 238 KDTKRLVLHMKNGAGCPCPQLDSLAGSFLVMGRKVDGQLLLM 279
+ + +LH+ CPCP + ++MG +VDG + ++
Sbjct: 502 EPLEVTLLHV--DWACPCPNVTVSEMPLIIMG-EVDGGMAML 540
>gi|38016904 thrombospondin repeat containing 1 isoform 1 [Homo
sapiens]
Length = 1074
Score = 31.2 bits (69), Expect = 1.3
Identities = 25/69 (36%), Positives = 31/69 (44%), Gaps = 7/69 (10%)
Query: 87 QQASSWLPLLAKRCHSDTQVFLCSLFAPVCLDRPIYPCRSLCEAVRAGCAPLMEAYGFPW 146
Q +WLPLL+ H+ + L SLFAP PI C E +RA C+ P
Sbjct: 333 QHPGAWLPLLSNGPHASS---LWSLFAP---SSPIPRCSGESEQLRA-CSQAPCPPEQPD 385
Query: 147 PEMLHCHKF 155
P L C F
Sbjct: 386 PRALQCAAF 394
>gi|153792694 baculoviral IAP repeat-containing 6 [Homo sapiens]
Length = 4857
Score = 31.2 bits (69), Expect = 1.3
Identities = 19/59 (32%), Positives = 27/59 (45%), Gaps = 2/59 (3%)
Query: 73 LPNLLEHESLAEVKQQASSWLPLLAKRCHSDTQVFLCSLFAPVCLDRPIYPCRSLCEAV 131
LP L HE V Q+ +L + CH+D +F+C + A + P LCE V
Sbjct: 2319 LPFTLAHERCISVVQKLVLFLLSMDFTCHADLLLFVCKVLARIA--NATRPTIHLCEIV 2375
>gi|56788359 thrombospondin repeat containing 1 isoform 2 [Homo
sapiens]
Length = 877
Score = 31.2 bits (69), Expect = 1.3
Identities = 25/69 (36%), Positives = 31/69 (44%), Gaps = 7/69 (10%)
Query: 87 QQASSWLPLLAKRCHSDTQVFLCSLFAPVCLDRPIYPCRSLCEAVRAGCAPLMEAYGFPW 146
Q +WLPLL+ H+ + L SLFAP PI C E +RA C+ P
Sbjct: 333 QHPGAWLPLLSNGPHASS---LWSLFAP---SSPIPRCSGESEQLRA-CSQAPCPPEQPD 385
Query: 147 PEMLHCHKF 155
P L C F
Sbjct: 386 PRALQCAAF 394
>gi|67782358 complement factor B preproprotein [Homo sapiens]
Length = 764
Score = 30.8 bits (68), Expect = 1.7
Identities = 24/84 (28%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Query: 161 LCIAVQFGHLPATAPPVTKICAQCEMEHSADGLMEQMCSSDFVVKMRIKEIKIENGDRKL 220
+C+ G A P T C Q + E ++ + S+ K+ KE+ I+NGD+K
Sbjct: 595 ICLPCTEGTTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKK- 653
Query: 221 IGAQKKKKLLKPGPLKRKDTKRLV 244
G+ ++ PG K KD +V
Sbjct: 654 -GSCERDAQYAPGYDKVKDISEVV 676
>gi|12232389 methyltransferase 11 domain containing 1 isoform 2
[Homo sapiens]
Length = 456
Score = 30.0 bits (66), Expect = 2.8
Identities = 17/42 (40%), Positives = 22/42 (52%), Gaps = 8/42 (19%)
Query: 254 PCPQLDSLAGSFLVMGRKVDGQLLLMAVYRWDKKNKEMKFAV 295
PCPQL +LA SF Q + W+KK KE KF++
Sbjct: 338 PCPQLTNLACSF--------SQAYHPIPFSWNKKPKEEKFSM 371
>gi|71999135 methyltransferase 11 domain containing 1 isoform 1
[Homo sapiens]
Length = 478
Score = 30.0 bits (66), Expect = 2.8
Identities = 17/42 (40%), Positives = 22/42 (52%), Gaps = 8/42 (19%)
Query: 254 PCPQLDSLAGSFLVMGRKVDGQLLLMAVYRWDKKNKEMKFAV 295
PCPQL +LA SF Q + W+KK KE KF++
Sbjct: 338 PCPQLTNLACSF--------SQAYHPIPFSWNKKPKEEKFSM 371
>gi|124517699 ankyrin repeat domain 13B [Homo sapiens]
Length = 626
Score = 29.6 bits (65), Expect = 3.7
Identities = 15/37 (40%), Positives = 23/37 (62%), Gaps = 5/37 (13%)
Query: 73 LPNLLE-----HESLAEVKQQASSWLPLLAKRCHSDT 104
+P LLE + E+K + +SW+PL++K C SDT
Sbjct: 116 IPVLLEKLRKAQDFYVEMKWEFTSWVPLVSKICPSDT 152
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.139 0.457
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,834,158
Number of Sequences: 37866
Number of extensions: 675015
Number of successful extensions: 1747
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1693
Number of HSP's gapped (non-prelim): 34
length of query: 317
length of database: 18,247,518
effective HSP length: 102
effective length of query: 215
effective length of database: 14,385,186
effective search space: 3092814990
effective search space used: 3092814990
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.