Guide to the Human Genome
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Search of human proteins with 187936961

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|187936961 transmembrane protein 129 isoform a [Homo sapiens]
         (362 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|187936961 transmembrane protein 129 isoform a [Homo sapiens]       748   0.0  
gi|19923909 transmembrane protein 129 isoform b [Homo sapiens]        462   e-130
gi|38490571 keratin associated protein 10-7 [Homo sapiens]             34   0.18 
gi|105990535 coagulation factor V precursor [Homo sapiens]             34   0.23 
gi|38490568 keratin associated protein 10-4 [Homo sapiens]             34   0.23 
gi|38490587 keratin associated protein 10-12 [Homo sapiens]            33   0.40 
gi|154759249 keratin associated protein 10-11 [Homo sapiens]           31   2.0  
gi|63053517 keratin associated protein 10-5 [Homo sapiens]             30   3.4  
gi|32140182 keratin associated protein 10-10 [Homo sapiens]            30   3.4  
gi|5453557 ariadne homolog 2 [Homo sapiens]                            30   4.4  
gi|5902054 ring finger protein 5 [Homo sapiens]                        29   5.7  
gi|22907025 apolipoprotein B mRNA editing enzyme, catalytic poly...    29   5.7  
gi|4758010 clock [Homo sapiens]                                        29   7.5  
gi|169217313 PREDICTED: similar to paraneoplastic antigen MA1 [H...    29   7.5  
gi|169216516 PREDICTED: similar to paraneoplastic antigen MA1 [H...    29   7.5  
gi|239746976 PREDICTED: similar to paraneoplastic antigen MA1 [H...    29   7.5  
gi|32880199 makorin ring finger protein 2 [Homo sapiens]               29   7.5  
gi|63053512 keratin associated protein 10-1 [Homo sapiens]             29   7.5  
gi|46250735 keratin associated protein 10-2 [Homo sapiens]             29   7.5  
gi|148727298 keratin associated protein 10-6 [Homo sapiens]            28   9.8  
gi|52487176 tripartite motif-containing 37 protein [Homo sapiens]      28   9.8  
gi|15147333 tripartite motif-containing 37 protein [Homo sapiens]      28   9.8  

>gi|187936961 transmembrane protein 129 isoform a [Homo sapiens]
          Length = 362

 Score =  748 bits (1930), Expect = 0.0
 Identities = 362/362 (100%), Positives = 362/362 (100%)

Query: 1   MDSPEVTFTLAYLVFAVCFVFTPNEFHAAGLTVQNLLSGWLGSEDAAFVPFHLRRTAATL 60
           MDSPEVTFTLAYLVFAVCFVFTPNEFHAAGLTVQNLLSGWLGSEDAAFVPFHLRRTAATL
Sbjct: 1   MDSPEVTFTLAYLVFAVCFVFTPNEFHAAGLTVQNLLSGWLGSEDAAFVPFHLRRTAATL 60

Query: 61  LCHSLLPLGYYVGMCLAASEKRLHALSQAPEAWRLFLLLAVTLPSIACILIYYWSRDRWA 120
           LCHSLLPLGYYVGMCLAASEKRLHALSQAPEAWRLFLLLAVTLPSIACILIYYWSRDRWA
Sbjct: 61  LCHSLLPLGYYVGMCLAASEKRLHALSQAPEAWRLFLLLAVTLPSIACILIYYWSRDRWA 120

Query: 121 CHPLARTLALYALPQSGWQAVASSVNTEFRRIDKFATGAPGARVIVTDTWVMKVTTYRVH 180
           CHPLARTLALYALPQSGWQAVASSVNTEFRRIDKFATGAPGARVIVTDTWVMKVTTYRVH
Sbjct: 121 CHPLARTLALYALPQSGWQAVASSVNTEFRRIDKFATGAPGARVIVTDTWVMKVTTYRVH 180

Query: 181 VAQQQDVHLTVTESRQHELSPDSNLPVQLLTIRVASTNPAVQAFDIWLNSTEYGELCEKL 240
           VAQQQDVHLTVTESRQHELSPDSNLPVQLLTIRVASTNPAVQAFDIWLNSTEYGELCEKL
Sbjct: 181 VAQQQDVHLTVTESRQHELSPDSNLPVQLLTIRVASTNPAVQAFDIWLNSTEYGELCEKL 240

Query: 241 RAPIRRAAHVVIHQSLGDLFLETFASLVEVNPAYSVPSSQELEACIGCMQTRASVKLVKT 300
           RAPIRRAAHVVIHQSLGDLFLETFASLVEVNPAYSVPSSQELEACIGCMQTRASVKLVKT
Sbjct: 241 RAPIRRAAHVVIHQSLGDLFLETFASLVEVNPAYSVPSSQELEACIGCMQTRASVKLVKT 300

Query: 301 CQEAATGECQQCYCRPMWCLTCMGKWFASRQDPLRPDTWLASRVPCPTCRARFCILDVCT 360
           CQEAATGECQQCYCRPMWCLTCMGKWFASRQDPLRPDTWLASRVPCPTCRARFCILDVCT
Sbjct: 301 CQEAATGECQQCYCRPMWCLTCMGKWFASRQDPLRPDTWLASRVPCPTCRARFCILDVCT 360

Query: 361 VR 362
           VR
Sbjct: 361 VR 362


>gi|19923909 transmembrane protein 129 isoform b [Homo sapiens]
          Length = 232

 Score =  462 bits (1190), Expect = e-130
 Identities = 227/227 (100%), Positives = 227/227 (100%)

Query: 1   MDSPEVTFTLAYLVFAVCFVFTPNEFHAAGLTVQNLLSGWLGSEDAAFVPFHLRRTAATL 60
           MDSPEVTFTLAYLVFAVCFVFTPNEFHAAGLTVQNLLSGWLGSEDAAFVPFHLRRTAATL
Sbjct: 1   MDSPEVTFTLAYLVFAVCFVFTPNEFHAAGLTVQNLLSGWLGSEDAAFVPFHLRRTAATL 60

Query: 61  LCHSLLPLGYYVGMCLAASEKRLHALSQAPEAWRLFLLLAVTLPSIACILIYYWSRDRWA 120
           LCHSLLPLGYYVGMCLAASEKRLHALSQAPEAWRLFLLLAVTLPSIACILIYYWSRDRWA
Sbjct: 61  LCHSLLPLGYYVGMCLAASEKRLHALSQAPEAWRLFLLLAVTLPSIACILIYYWSRDRWA 120

Query: 121 CHPLARTLALYALPQSGWQAVASSVNTEFRRIDKFATGAPGARVIVTDTWVMKVTTYRVH 180
           CHPLARTLALYALPQSGWQAVASSVNTEFRRIDKFATGAPGARVIVTDTWVMKVTTYRVH
Sbjct: 121 CHPLARTLALYALPQSGWQAVASSVNTEFRRIDKFATGAPGARVIVTDTWVMKVTTYRVH 180

Query: 181 VAQQQDVHLTVTESRQHELSPDSNLPVQLLTIRVASTNPAVQAFDIW 227
           VAQQQDVHLTVTESRQHELSPDSNLPVQLLTIRVASTNPAVQAFDIW
Sbjct: 181 VAQQQDVHLTVTESRQHELSPDSNLPVQLLTIRVASTNPAVQAFDIW 227


>gi|38490571 keratin associated protein 10-7 [Homo sapiens]
          Length = 370

 Score = 34.3 bits (77), Expect = 0.18
 Identities = 26/75 (34%), Positives = 33/75 (44%), Gaps = 3/75 (4%)

Query: 278 SSQELEACIGCMQTRAS-VKLVKTCQEAATGECQQCYCRPMWCLTCMGKWFASRQDPLRP 336
           SSQ  + C  C+      V  V  C  A+T  CQQ  C+P  C T   +  +S     RP
Sbjct: 258 SSQSQQGC--CVPVCCKPVCCVPVCSGASTSCCQQSSCQPACCTTSCCRPSSSVSLLCRP 315

Query: 337 DTWLASRVPCPTCRA 351
               A  VP P+C A
Sbjct: 316 VCRPACCVPVPSCCA 330


>gi|105990535 coagulation factor V precursor [Homo sapiens]
          Length = 2224

 Score = 33.9 bits (76), Expect = 0.23
 Identities = 42/174 (24%), Positives = 69/174 (39%), Gaps = 38/174 (21%)

Query: 72   VGMCLAASEKRLHALSQAPEAWRLFLLLAVTLPSIACILIYYWSRDRWACHPLARTLALY 131
            +G  L   +  LH  S  P   R F+LL +T         YY  + R             
Sbjct: 1745 IGPLLICQKGILHKDSNMPMDMREFVLLFMTFDEKKSW--YYEKKSR------------- 1789

Query: 132  ALPQSGWQAVASSVNT--EFRRIDKFATGAPGARVIVTDTWVMKVTTYRVHVAQQQDVHL 189
                S W+  +S +    EF  I+      PG ++   + WV     + +++   QD+H+
Sbjct: 1790 ----SSWRLTSSEMKKSHEFHAINGMIYSLPGLKMYEQE-WVR---LHLLNIGGSQDIHV 1841

Query: 190  ------TVTES--RQHELSPDSNLPVQLLTIRVASTNPAVQAFDIWLNSTEYGE 235
                  T+ E+  +QH+L     LP    T+ + ++ P       WL +TE GE
Sbjct: 1842 VHFHGQTLLENGNKQHQLGVWPLLPGSFKTLEMKASKPG-----WWLLNTEVGE 1890


>gi|38490568 keratin associated protein 10-4 [Homo sapiens]
          Length = 401

 Score = 33.9 bits (76), Expect = 0.23
 Identities = 25/75 (33%), Positives = 33/75 (44%), Gaps = 3/75 (4%)

Query: 278 SSQELEACIGCMQTRAS-VKLVKTCQEAATGECQQCYCRPMWCLTCMGKWFASRQDPLRP 336
           SSQ  + C  C+      V  V  C  A++  CQQ  C+P  C T   +  +S     RP
Sbjct: 310 SSQSQQGC--CVPVCCKPVSCVPVCSGASSSCCQQSSCQPACCTTSCCRPSSSVSLLCRP 367

Query: 337 DTWLASRVPCPTCRA 351
               A  VP P+C A
Sbjct: 368 VCRPACCVPVPSCCA 382


>gi|38490587 keratin associated protein 10-12 [Homo sapiens]
          Length = 245

 Score = 33.1 bits (74), Expect = 0.40
 Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 4/79 (5%)

Query: 272 PAYSVPSSQELEACIG-CMQTRASVKLVKTCQEAATGECQQCYCRPMWCLTCMGKWFASR 330
           PA  + S  +   C+  C +    +  V  C  A++  CQQ  C+P  C T   +  +S 
Sbjct: 139 PACCISSPCQQSCCVPVCCKP---ICCVPVCSGASSLCCQQSSCQPACCTTSCCRPSSSV 195

Query: 331 QDPLRPDTWLASRVPCPTC 349
               RP    A RVP P+C
Sbjct: 196 SLLCRPVCRPARRVPVPSC 214


>gi|154759249 keratin associated protein 10-11 [Homo sapiens]
          Length = 298

 Score = 30.8 bits (68), Expect = 2.0
 Identities = 24/87 (27%), Positives = 35/87 (40%), Gaps = 14/87 (16%)

Query: 272 PAYSVPSSQELEACIG-CMQTR--ASVKLVKTCQEAATGECQQCYCRPMWCLTCMGKWFA 328
           PA    SS +   C+  C +T     +  V  C  A++  CQQ  C+P  C T       
Sbjct: 176 PACCTSSSYQQACCVPVCCKTVYCKPICCVPVCSRASSSRCQQPSCQPACCTTSC----- 230

Query: 329 SRQDPLRPDTWLASRVPCPTCRARFCI 355
                 RP +   S +  P CR+  C+
Sbjct: 231 -----CRPSS-SVSLLCHPVCRSTCCV 251


>gi|63053517 keratin associated protein 10-5 [Homo sapiens]
          Length = 271

 Score = 30.0 bits (66), Expect = 3.4
 Identities = 19/54 (35%), Positives = 24/54 (44%)

Query: 298 VKTCQEAATGECQQCYCRPMWCLTCMGKWFASRQDPLRPDTWLASRVPCPTCRA 351
           V  C  A+T  CQQ  C+P  C T   +  +S     RP    A  VP  +C A
Sbjct: 189 VPVCSGASTSCCQQSSCQPACCTTSCCRPSSSVSLLCRPICRPACCVPISSCCA 242


>gi|32140182 keratin associated protein 10-10 [Homo sapiens]
          Length = 251

 Score = 30.0 bits (66), Expect = 3.4
 Identities = 19/58 (32%), Positives = 24/58 (41%)

Query: 294 SVKLVKTCQEAATGECQQCYCRPMWCLTCMGKWFASRQDPLRPDTWLASRVPCPTCRA 351
           SV  V  C  A+T  CQQ  C+P  C     +  +S      P       VP P+C A
Sbjct: 154 SVCYVPVCSGASTSCCQQSSCQPACCTASCCRPSSSVSLLCHPVCKSTCCVPVPSCGA 211


>gi|5453557 ariadne homolog 2 [Homo sapiens]
          Length = 493

 Score = 29.6 bits (65), Expect = 4.4
 Identities = 17/55 (30%), Positives = 22/55 (40%), Gaps = 7/55 (12%)

Query: 268 VEVNPAYSVPSSQELEACIGCMQTRASVKLVKTCQEAATGECQQCYCRPMWCLTC 322
           V+ NP+  VP+S     C  CMQ      L+          CQ  +CR  W   C
Sbjct: 122 VQPNPSKHVPTSHPPHHCAVCMQFVRKENLLSLA-------CQHQFCRSCWEQHC 169



 Score = 28.5 bits (62), Expect = 9.8
 Identities = 21/83 (25%), Positives = 31/83 (37%), Gaps = 10/83 (12%)

Query: 276 VPSSQELEACIGC--------MQTRASVKLVKTCQEAATGECQQCYCRPMWCLTCMGKWF 327
           V S  +L+ C G          + RA       C E    +C+Q Y  P  C T + KW 
Sbjct: 219 VESHYQLQLCPGADCPMVIRVQEPRARRVQCNRCNEVFCFKCRQMYHAPTDCAT-IRKWL 277

Query: 328 ASRQDPLRPDTWLASRV-PCPTC 349
               D      ++++    CP C
Sbjct: 278 TKCADDSETANYISAHTKDCPKC 300


>gi|5902054 ring finger protein 5 [Homo sapiens]
          Length = 180

 Score = 29.3 bits (64), Expect = 5.7
 Identities = 15/54 (27%), Positives = 23/54 (42%), Gaps = 15/54 (27%)

Query: 298 VKTCQEAATGECQQCYCRPMWCLTCMGKWFASRQDPLRPDTWLASRVPCPTCRA 351
           ++T +EA    C   YC P     C+ +W  +R +          R  CP C+A
Sbjct: 31  LETAREAVVSVCGHLYCWP-----CLHQWLETRPE----------RQECPVCKA 69


>gi|22907025 apolipoprotein B mRNA editing enzyme, catalytic
           polypeptide-like 3B [Homo sapiens]
          Length = 382

 Score = 29.3 bits (64), Expect = 5.7
 Identities = 16/46 (34%), Positives = 19/46 (41%), Gaps = 4/46 (8%)

Query: 311 QCYCRPMW-CLTCMGKWFASRQDPLRPD---TWLASRVPCPTCRAR 352
           Q Y +P +    C   WF   Q P       TW  S  PCP C A+
Sbjct: 58  QVYFKPQYHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAK 103


>gi|4758010 clock [Homo sapiens]
          Length = 846

 Score = 28.9 bits (63), Expect = 7.5
 Identities = 36/120 (30%), Positives = 54/120 (45%), Gaps = 30/120 (25%)

Query: 132 ALPQSGWQAVASSVNTEFRRIDKFATG---------APGA--RVIVTDTWVMK--VTTYR 178
           ++PQ+  Q+ A +  T+ R+I +F+ G         AP A   V+V  T +M   VT Y 
Sbjct: 681 SMPQNSTQSAAVTTFTQDRQI-RFSQGQQLVTKLVTAPVACGAVMVPSTMLMGQVVTAYP 739

Query: 179 VHVAQQQDVH-LTVTESRQHELSPDSNL--------------PVQLL-TIRVASTNPAVQ 222
               QQQ    L+VT+ +Q + S +  L              P Q L T R+   NP+ Q
Sbjct: 740 TFATQQQQSQTLSVTQQQQQQSSQEQQLTSVQQPSQAQLTQPPQQFLQTSRLLHGNPSTQ 799


>gi|169217313 PREDICTED: similar to paraneoplastic antigen MA1 [Homo
           sapiens]
          Length = 601

 Score = 28.9 bits (63), Expect = 7.5
 Identities = 14/31 (45%), Positives = 18/31 (58%), Gaps = 6/31 (19%)

Query: 319 CLTCMGKWFASRQDPLRPDTWLASRVPCPTC 349
           CLT +G+ F SR      DTW+ SR+   TC
Sbjct: 369 CLTALGQVFRSR------DTWMTSRMKFLTC 393


>gi|169216516 PREDICTED: similar to paraneoplastic antigen MA1 [Homo
           sapiens]
          Length = 541

 Score = 28.9 bits (63), Expect = 7.5
 Identities = 14/31 (45%), Positives = 18/31 (58%), Gaps = 6/31 (19%)

Query: 319 CLTCMGKWFASRQDPLRPDTWLASRVPCPTC 349
           CLT +G+ F SR      DTW+ SR+   TC
Sbjct: 309 CLTALGQVFRSR------DTWMTSRMKFLTC 333


>gi|239746976 PREDICTED: similar to paraneoplastic antigen MA1 [Homo
           sapiens]
          Length = 601

 Score = 28.9 bits (63), Expect = 7.5
 Identities = 14/31 (45%), Positives = 18/31 (58%), Gaps = 6/31 (19%)

Query: 319 CLTCMGKWFASRQDPLRPDTWLASRVPCPTC 349
           CLT +G+ F SR      DTW+ SR+   TC
Sbjct: 369 CLTALGQVFRSR------DTWMTSRMKFLTC 393


>gi|32880199 makorin ring finger protein 2 [Homo sapiens]
          Length = 416

 Score = 28.9 bits (63), Expect = 7.5
 Identities = 26/120 (21%), Positives = 48/120 (40%), Gaps = 18/120 (15%)

Query: 233 YGELCEKLRAPIRRAAHVVIHQSLGDLFLETFASLVEVNPAYSVPSSQELEACIGCMQTR 292
           +GE+CE  R  +         ++   + + TF    E+  A++  +SQ+ + C  CM+  
Sbjct: 189 HGEVCEICRLQVLHPFDPEQRKAHEKICMLTFEH--EMEKAFAFQASQD-KVCSICMEVI 245

Query: 293 ASVKLVKTCQEAATGECQQCYCRPMWCLTCMGKWFASRQ--DPLRPDTWLASRVPCPTCR 350
                    +      C   YC     L+C+ +W  ++Q  +P+           CP CR
Sbjct: 246 LEKASASERRFGILSNCNHTYC-----LSCIRQWRCAKQFENPIIKS--------CPECR 292


>gi|63053512 keratin associated protein 10-1 [Homo sapiens]
          Length = 282

 Score = 28.9 bits (63), Expect = 7.5
 Identities = 18/54 (33%), Positives = 24/54 (44%)

Query: 298 VKTCQEAATGECQQCYCRPMWCLTCMGKWFASRQDPLRPDTWLASRVPCPTCRA 351
           V  C  A+T  CQQ  C+P  C T   +  +S     RP    A  +P  +C A
Sbjct: 200 VPVCSGASTSCCQQSSCQPACCTTSCCRPSSSVSLLCRPVCRPACCMPVSSCCA 253


>gi|46250735 keratin associated protein 10-2 [Homo sapiens]
          Length = 255

 Score = 28.9 bits (63), Expect = 7.5
 Identities = 19/68 (27%), Positives = 30/68 (44%), Gaps = 13/68 (19%)

Query: 294 SVKLVKTCQEAATGECQQCYCRPMWCLTCMGKWFASRQDPLRPDTWLASRVPC-PTCRAR 352
           +V  V TC E+++  CQQ  C+P  C +           P +    ++  V C P C   
Sbjct: 148 AVCCVPTCSESSSSCCQQSSCQPACCTS----------SPCQQSCCVS--VCCKPVCCKS 195

Query: 353 FCILDVCT 360
            C + VC+
Sbjct: 196 ICCVPVCS 203


>gi|148727298 keratin associated protein 10-6 [Homo sapiens]
          Length = 365

 Score = 28.5 bits (62), Expect = 9.8
 Identities = 17/54 (31%), Positives = 22/54 (40%)

Query: 298 VKTCQEAATGECQQCYCRPMWCLTCMGKWFASRQDPLRPDTWLASRVPCPTCRA 351
           V  C  A+T  CQQ  C+P  C     +  +S      P       VP P+C A
Sbjct: 272 VPVCSGASTSCCQQSSCQPACCTASCCRPSSSVSLLCHPVCKSTCCVPVPSCGA 325


>gi|52487176 tripartite motif-containing 37 protein [Homo sapiens]
          Length = 964

 Score = 28.5 bits (62), Expect = 9.8
 Identities = 19/88 (21%), Positives = 31/88 (35%), Gaps = 25/88 (28%)

Query: 275 SVPSSQELEACIGCMQTRASVKLVKTCQEAATGECQQCYCRPMWCLTCMGKWFASRQDPL 334
           SV S  E+  C  CM+     +L               +C  + C +C+ +W   +    
Sbjct: 5   SVESIAEVFRCFICMEKLRDARLCP-------------HCSKLCCFSCIRRWLTEQ---- 47

Query: 335 RPDTWLASRVPCPTCRARFCILDVCTVR 362
                   R  CP CRA   + ++   R
Sbjct: 48  --------RAQCPHCRAPLQLRELVNCR 67


>gi|15147333 tripartite motif-containing 37 protein [Homo sapiens]
          Length = 964

 Score = 28.5 bits (62), Expect = 9.8
 Identities = 19/88 (21%), Positives = 31/88 (35%), Gaps = 25/88 (28%)

Query: 275 SVPSSQELEACIGCMQTRASVKLVKTCQEAATGECQQCYCRPMWCLTCMGKWFASRQDPL 334
           SV S  E+  C  CM+     +L               +C  + C +C+ +W   +    
Sbjct: 5   SVESIAEVFRCFICMEKLRDARLCP-------------HCSKLCCFSCIRRWLTEQ---- 47

Query: 335 RPDTWLASRVPCPTCRARFCILDVCTVR 362
                   R  CP CRA   + ++   R
Sbjct: 48  --------RAQCPHCRAPLQLRELVNCR 67


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.134    0.440 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,032,595
Number of Sequences: 37866
Number of extensions: 595240
Number of successful extensions: 1906
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 1873
Number of HSP's gapped (non-prelim): 56
length of query: 362
length of database: 18,247,518
effective HSP length: 104
effective length of query: 258
effective length of database: 14,309,454
effective search space: 3691839132
effective search space used: 3691839132
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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