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Search of human proteins with 18765707
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18765707 inositol polyphosphate-5-phosphatase K isoform 2
[Homo sapiens]
(372 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|208610044 inositol polyphosphate-5-phosphatase K isoform 2 [H... 782 0.0
gi|18765707 inositol polyphosphate-5-phosphatase K isoform 2 [Ho... 782 0.0
gi|18765709 inositol polyphosphate-5-phosphatase K isoform 1 [Ho... 782 0.0
gi|50726960 phosphatidylinositol (4,5) bisphosphate 5-phosphatas... 337 1e-92
gi|113722125 inositol polyphosphate-5-phosphatase, 75kDa precurs... 165 5e-41
gi|13325070 phosphatidylinositol polyphosphate 5-phosphatase iso... 138 7e-33
gi|13325072 phosphatidylinositol polyphosphate 5-phosphatase iso... 138 7e-33
gi|237757312 synaptojanin 1 isoform c [Homo sapiens] 125 6e-29
gi|237757310 synaptojanin 1 isoform a [Homo sapiens] 125 6e-29
gi|237757308 synaptojanin 1 isoform b [Homo sapiens] 125 6e-29
gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 125 6e-29
gi|26190608 synaptojanin 2 [Homo sapiens] 123 3e-28
gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo sap... 103 2e-22
gi|40254823 SH2 containing inositol phosphatase isoform b [Homo ... 94 3e-19
gi|64085167 SH2 containing inositol phosphatase isoform a [Homo ... 94 3e-19
gi|38327539 inositol polyphosphate-5-phosphatase E [Homo sapiens] 75 1e-13
gi|119943086 Tax1 (human T-cell leukemia virus type I) binding p... 42 9e-04
gi|21361682 Tax1 (human T-cell leukemia virus type I) binding pr... 42 9e-04
gi|5031937 calcium binding and coiled-coil domain 2 [Homo sapiens] 40 0.003
gi|14149742 coiled-coil transcriptional coactivator isoform 1 [H... 37 0.022
gi|109702906 inositol polyphosphate-5-phosphatase A [Homo sapiens] 32 1.2
gi|66392146 RNA U, small nuclear RNA export adaptor (phosphoryla... 30 3.5
gi|62241001 conserved helix-loop-helix ubiquitous kinase [Homo s... 29 6.0
gi|27477111 step II splicing factor SLU7 [Homo sapiens] 29 6.0
gi|223468681 v-rel reticuloendotheliosis viral oncogene homolog ... 29 7.8
gi|223468676 v-rel reticuloendotheliosis viral oncogene homolog ... 29 7.8
gi|219521893 coiled-coil transcriptional coactivator isoform 2 [... 29 7.8
>gi|208610044 inositol polyphosphate-5-phosphatase K isoform 2 [Homo
sapiens]
Length = 372
Score = 782 bits (2020), Expect = 0.0
Identities = 372/372 (100%), Positives = 372/372 (100%)
Query: 1 MDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICL 60
MDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICL
Sbjct: 1 MDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICL 60
Query: 61 KLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFR 120
KLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFR
Sbjct: 61 KLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFR 120
Query: 121 IEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDY 180
IEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDY
Sbjct: 121 IEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDY 180
Query: 181 DTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSG 240
DTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSG
Sbjct: 181 DTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSG 240
Query: 241 TFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDY 300
TFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDY
Sbjct: 241 TFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDY 300
Query: 301 VSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLRSVVGISRPFQIPPGSL 360
VSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLRSVVGISRPFQIPPGSL
Sbjct: 301 VSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLRSVVGISRPFQIPPGSL 360
Query: 361 REDPLGEAQPQI 372
REDPLGEAQPQI
Sbjct: 361 REDPLGEAQPQI 372
>gi|18765707 inositol polyphosphate-5-phosphatase K isoform 2 [Homo
sapiens]
Length = 372
Score = 782 bits (2020), Expect = 0.0
Identities = 372/372 (100%), Positives = 372/372 (100%)
Query: 1 MDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICL 60
MDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICL
Sbjct: 1 MDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICL 60
Query: 61 KLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFR 120
KLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFR
Sbjct: 61 KLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFR 120
Query: 121 IEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDY 180
IEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDY
Sbjct: 121 IEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDY 180
Query: 181 DTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSG 240
DTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSG
Sbjct: 181 DTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSG 240
Query: 241 TFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDY 300
TFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDY
Sbjct: 241 TFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDY 300
Query: 301 VSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLRSVVGISRPFQIPPGSL 360
VSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLRSVVGISRPFQIPPGSL
Sbjct: 301 VSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLRSVVGISRPFQIPPGSL 360
Query: 361 REDPLGEAQPQI 372
REDPLGEAQPQI
Sbjct: 361 REDPLGEAQPQI 372
>gi|18765709 inositol polyphosphate-5-phosphatase K isoform 1 [Homo
sapiens]
Length = 448
Score = 782 bits (2020), Expect = 0.0
Identities = 372/372 (100%), Positives = 372/372 (100%)
Query: 1 MDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICL 60
MDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICL
Sbjct: 77 MDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICL 136
Query: 61 KLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFR 120
KLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFR
Sbjct: 137 KLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFR 196
Query: 121 IEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDY 180
IEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDY
Sbjct: 197 IEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDY 256
Query: 181 DTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSG 240
DTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSG
Sbjct: 257 DTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSG 316
Query: 241 TFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDY 300
TFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDY
Sbjct: 317 TFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDY 376
Query: 301 VSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLRSVVGISRPFQIPPGSL 360
VSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLRSVVGISRPFQIPPGSL
Sbjct: 377 VSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLRSVVGISRPFQIPPGSL 436
Query: 361 REDPLGEAQPQI 372
REDPLGEAQPQI
Sbjct: 437 REDPLGEAQPQI 448
>gi|50726960 phosphatidylinositol (4,5) bisphosphate 5-phosphatase,
A [Homo sapiens]
Length = 638
Score = 337 bits (864), Expect = 1e-92
Identities = 167/355 (47%), Positives = 221/355 (62%), Gaps = 3/355 (0%)
Query: 1 MDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICL 60
MD L P +F+ VS VRMQG++LL+FAKY HLP+++ + T T TGL GYWGNKGGV++ L
Sbjct: 120 MDALGPFNFVLVSSVRMQGVILLLFAKYYHLPFLRDVQTDCTRTGLGGYWGNKGGVSVRL 179
Query: 61 KLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFR 120
+G+ + +NCHLP H+ QR ++F IL +Q +G ILDHDL+ WFGD+NFR
Sbjct: 180 AAFGHMLCFLNCHLPAHMDKAEQRKDNFQTILSLQQFQGPGAQGILDHDLVFWFGDLNFR 239
Query: 121 IEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDY 180
IE + LHFV+ +I + LWEKDQL++AK P+L+ FQEG L F PT+KFD +N Y
Sbjct: 240 IESYDLHFVKFAIDSDQLHQLWEKDQLNMAKNTWPILKGFQEGPLNFAPTFKFDVGTNKY 299
Query: 181 DTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSG 240
DTS KKRKPAWTDRILW++K P GP + ++ Y SHM Y +SDHKPV+
Sbjct: 300 DTSAKKRKPAWTDRILWKVK-APGGGPSPSGRKSHRLQVTQHSYRSHMEYTVSDHKPVAA 358
Query: 241 TFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDY 300
F L+ PL+ L D W +V Y + F S WDWIGLY+VG R DY
Sbjct: 359 QFLLQFAFRDDMPLVRLEVADEWVRPEQAVVRYRMETVFARSSWDWIGLYRVGFRHCKDY 418
Query: 301 VSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLRSVVGISRPFQI 355
V+Y W V N QV ++P +F+L YYS++ ++GI+ PFQI
Sbjct: 419 VAYVWAKHEDV--DGNTYQVTFSEESLPKGHGDFILGYYSHNHSILIGITEPFQI 471
>gi|113722125 inositol polyphosphate-5-phosphatase, 75kDa precursor
[Homo sapiens]
Length = 913
Score = 165 bits (418), Expect = 5e-41
Identities = 90/243 (37%), Positives = 135/243 (55%), Gaps = 21/243 (8%)
Query: 9 FIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVS 68
+ KV +R+ GI+LL++ K +H YI + ++ TG+ G GNKGGV I + + +
Sbjct: 336 YAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQFHNTSIC 395
Query: 69 IINCHLPPHISNNYQRLEHFDRILE-MQNCE-GRDIP--NILDHDLIIWFGDMNFRIEDF 124
++N HL HI +R + + I MQ C+ +P I +HD+I+W GD+N+RIE+
Sbjct: 396 VVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPLTISNHDVILWLGDLNYRIEEL 455
Query: 125 GLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSE 184
+ V++ I+ + + L+ DQL I + F EG L F PTYK+D S+D+DTSE
Sbjct: 456 DVEKVKKLIEEKDFQMLYAYDQLKIQVAAKTVFEGFTEGELTFQPTYKYDTGSDDWDTSE 515
Query: 185 KKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSGTFDL 244
K R PAW DRILW+ K +++ Y SHM SDHKPVS FD+
Sbjct: 516 KCRAPAWCDRILWKGK-----------------NITQLSYQSHMALKTSDHKPVSSVFDI 558
Query: 245 ELK 247
++
Sbjct: 559 GVR 561
>gi|13325070 phosphatidylinositol polyphosphate 5-phosphatase
isoform b [Homo sapiens]
Length = 893
Score = 138 bits (348), Expect = 7e-33
Identities = 81/247 (32%), Positives = 129/247 (52%), Gaps = 21/247 (8%)
Query: 5 SPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYG 64
S + KV VR+ G++LL+FA+ YI+ ++T++ TG+ G GNKGGV + +
Sbjct: 307 SKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHN 366
Query: 65 YYVSIINCHLPPHISNNYQRLEHFDRILEMQN--CEGRDIP--NILDHDLIIWFGDMNFR 120
I+N HL H+ + +R + + I + + +P NI+ H+++IW GD+N+R
Sbjct: 367 TTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIWLGDLNYR 426
Query: 121 IEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDY 180
+ + V+ I + L + DQL+I + +F EG + F PTYK+D ++ +
Sbjct: 427 LCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRW 486
Query: 181 DTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSG 240
D+S K R PAW DRILWR +++ Y SHM SDHKPVS
Sbjct: 487 DSSGKCRVPAWCDRILWR-----------------GTNVNQLNYRSHMELKTSDHKPVSA 529
Query: 241 TFDLELK 247
F + +K
Sbjct: 530 LFHIGVK 536
>gi|13325072 phosphatidylinositol polyphosphate 5-phosphatase
isoform a [Homo sapiens]
Length = 901
Score = 138 bits (348), Expect = 7e-33
Identities = 81/247 (32%), Positives = 129/247 (52%), Gaps = 21/247 (8%)
Query: 5 SPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYG 64
S + KV VR+ G++LL+FA+ YI+ ++T++ TG+ G GNKGGV + +
Sbjct: 307 SKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHN 366
Query: 65 YYVSIINCHLPPHISNNYQRLEHFDRILEMQN--CEGRDIP--NILDHDLIIWFGDMNFR 120
I+N HL H+ + +R + + I + + +P NI+ H+++IW GD+N+R
Sbjct: 367 TTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIWLGDLNYR 426
Query: 121 IEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDY 180
+ + V+ I + L + DQL+I + +F EG + F PTYK+D ++ +
Sbjct: 427 LCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRW 486
Query: 181 DTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSG 240
D+S K R PAW DRILWR +++ Y SHM SDHKPVS
Sbjct: 487 DSSGKCRVPAWCDRILWR-----------------GTNVNQLNYRSHMELKTSDHKPVSA 529
Query: 241 TFDLELK 247
F + +K
Sbjct: 530 LFHIGVK 536
>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
Length = 1295
Score = 125 bits (314), Expect = 6e-29
Identities = 84/250 (33%), Positives = 128/250 (51%), Gaps = 16/250 (6%)
Query: 9 FIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVS 68
++ ++ ++ G+ L VF + QH P+I+ ++ + TG+ G GNKG V I + + +
Sbjct: 625 YVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLC 684
Query: 69 IINCHLPPHISNNYQRLEHFDRILEMQNCE-GRDIPNILDHDLIIWFGDMNFRIEDFGLH 127
+ H S +R E F I + GR + HD + W GD N+RI D
Sbjct: 685 FVCSHFAAGQSQVKERNEDFIEIARKLSFPMGR---MLFSHDYVFWCGDFNYRI-DLPNE 740
Query: 128 FVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSEKKR 187
V+E I+ + + L DQL K + R F EG++ F PTYK+D S+DYDTSEK R
Sbjct: 741 EVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCR 800
Query: 188 KPAWTDRILWRLKRQPC--AGPDTPIPPASHFSLSLRGYS----SHMTYG-----ISDHK 236
PAWTDR+LWR ++ P + D + AS S Y+ + + YG SDH+
Sbjct: 801 TPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHR 860
Query: 237 PVSGTFDLEL 246
PV D+++
Sbjct: 861 PVVALIDIDI 870
>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
Length = 1612
Score = 125 bits (314), Expect = 6e-29
Identities = 84/250 (33%), Positives = 128/250 (51%), Gaps = 16/250 (6%)
Query: 9 FIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVS 68
++ ++ ++ G+ L VF + QH P+I+ ++ + TG+ G GNKG V I + + +
Sbjct: 664 YVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLC 723
Query: 69 IINCHLPPHISNNYQRLEHFDRILEMQNCE-GRDIPNILDHDLIIWFGDMNFRIEDFGLH 127
+ H S +R E F I + GR + HD + W GD N+RI D
Sbjct: 724 FVCSHFAAGQSQVKERNEDFIEIARKLSFPMGR---MLFSHDYVFWCGDFNYRI-DLPNE 779
Query: 128 FVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSEKKR 187
V+E I+ + + L DQL K + R F EG++ F PTYK+D S+DYDTSEK R
Sbjct: 780 EVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCR 839
Query: 188 KPAWTDRILWRLKRQPC--AGPDTPIPPASHFSLSLRGYS----SHMTYG-----ISDHK 236
PAWTDR+LWR ++ P + D + AS S Y+ + + YG SDH+
Sbjct: 840 TPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHR 899
Query: 237 PVSGTFDLEL 246
PV D+++
Sbjct: 900 PVVALIDIDI 909
>gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
Length = 1350
Score = 125 bits (314), Expect = 6e-29
Identities = 84/250 (33%), Positives = 128/250 (51%), Gaps = 16/250 (6%)
Query: 9 FIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVS 68
++ ++ ++ G+ L VF + QH P+I+ ++ + TG+ G GNKG V I + + +
Sbjct: 664 YVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLC 723
Query: 69 IINCHLPPHISNNYQRLEHFDRILEMQNCE-GRDIPNILDHDLIIWFGDMNFRIEDFGLH 127
+ H S +R E F I + GR + HD + W GD N+RI D
Sbjct: 724 FVCSHFAAGQSQVKERNEDFIEIARKLSFPMGR---MLFSHDYVFWCGDFNYRI-DLPNE 779
Query: 128 FVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSEKKR 187
V+E I+ + + L DQL K + R F EG++ F PTYK+D S+DYDTSEK R
Sbjct: 780 EVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCR 839
Query: 188 KPAWTDRILWRLKRQPC--AGPDTPIPPASHFSLSLRGYS----SHMTYG-----ISDHK 236
PAWTDR+LWR ++ P + D + AS S Y+ + + YG SDH+
Sbjct: 840 TPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHR 899
Query: 237 PVSGTFDLEL 246
PV D+++
Sbjct: 900 PVVALIDIDI 909
>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
Length = 1526
Score = 125 bits (314), Expect = 6e-29
Identities = 84/250 (33%), Positives = 128/250 (51%), Gaps = 16/250 (6%)
Query: 9 FIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVS 68
++ ++ ++ G+ L VF + QH P+I+ ++ + TG+ G GNKG V I + + +
Sbjct: 620 YVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLC 679
Query: 69 IINCHLPPHISNNYQRLEHFDRILEMQNCE-GRDIPNILDHDLIIWFGDMNFRIEDFGLH 127
+ H S +R E F I + GR + HD + W GD N+RI D
Sbjct: 680 FVCSHFAAGQSQVKERNEDFIEIARKLSFPMGR---MLFSHDYVFWCGDFNYRI-DLPNE 735
Query: 128 FVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSEKKR 187
V+E I+ + + L DQL K + R F EG++ F PTYK+D S+DYDTSEK R
Sbjct: 736 EVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCR 795
Query: 188 KPAWTDRILWRLKRQPC--AGPDTPIPPASHFSLSLRGYS----SHMTYG-----ISDHK 236
PAWTDR+LWR ++ P + D + AS S Y+ + + YG SDH+
Sbjct: 796 TPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHR 855
Query: 237 PVSGTFDLEL 246
PV D+++
Sbjct: 856 PVVALIDIDI 865
>gi|26190608 synaptojanin 2 [Homo sapiens]
Length = 1496
Score = 123 bits (308), Expect = 3e-28
Identities = 81/252 (32%), Positives = 123/252 (48%), Gaps = 18/252 (7%)
Query: 9 FIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVS 68
+I ++ ++ G+ L +F + H+P+I+ ++ + TG+ G GNKG V I + +
Sbjct: 621 YILLTSAQLVGVCLYIFVRPYHVPFIRDVAIDTVKTGMGGKAGNKGAVGIRFQFHSTSFC 680
Query: 69 IINCHLPPHISNNYQRLEHFDRILEMQNC--EGRDIPNILDHDLIIWFGDMNFRIEDFGL 126
I HL S +R E + I + + C GR N+ HD + W GD N+RI D
Sbjct: 681 FICSHLTAGQSQVKERNEDYKEITQ-KLCFPMGR---NVFSHDYVFWCGDFNYRI-DLTY 735
Query: 127 HFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSEKK 186
V +K + + L E DQL + K + ++F EG + F PTYK+D S YDTS+K
Sbjct: 736 EEVFYFVKRQDWKKLLEFDQLQLQKSSGKIFKDFHEGAINFGPTYKYDVGSAAYDTSDKC 795
Query: 187 RKPAWTDRILWRLKRQP---CAGP--------DTPIPPASHFSLSLRGYSSHMTYGISDH 235
R PAWTDR+LW K+ P AG D +S Y SDH
Sbjct: 796 RTPAWTDRVLWWRKKHPFDKTAGELNLLDSDLDVDTKVRHTWSPGALQYYGRAELQASDH 855
Query: 236 KPVSGTFDLELK 247
+PV ++E++
Sbjct: 856 RPVLAIVEVEVQ 867
>gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo
sapiens]
Length = 1258
Score = 103 bits (257), Expect = 2e-22
Identities = 70/252 (27%), Positives = 114/252 (45%), Gaps = 27/252 (10%)
Query: 4 LSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLY 63
L+ L + ++ + I + V K +H I +ST S TG+ GNKG V +
Sbjct: 492 LTDLDYRPIAMQSLWNIKVAVLVKPEHENRISHVSTSSVKTGIANTLGNKGAVGVSFMFN 551
Query: 64 GYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDL----IIWFGDMNF 119
G +NCHL +R +++ IL + + R + N D L + WFGD+N+
Sbjct: 552 GTSFGFVNCHLTSGNEKTARRNQNYLDILRLLSLGDRQL-NAFDISLRFTHLFWFGDLNY 610
Query: 120 RIEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSND 179
R+ D + + I + + L DQL++ ++ + F E + FPPTY+++R S D
Sbjct: 611 RL-DMDIQEILNYISRKEFEPLLRVDQLNLEREKHKVFLRFSEEEISFPPTYRYERGSRD 669
Query: 180 -------YDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGI 232
T + P+W DRILW+ P +H + G + +
Sbjct: 670 TYAWHKQKPTGVRTNVPSWCDRILWKSY------------PETHIICNSYGCTDDIV--T 715
Query: 233 SDHKPVSGTFDL 244
SDH PV GTF++
Sbjct: 716 SDHSPVFGTFEV 727
>gi|40254823 SH2 containing inositol phosphatase isoform b [Homo
sapiens]
Length = 1188
Score = 93.6 bits (231), Expect = 3e-19
Identities = 66/252 (26%), Positives = 111/252 (44%), Gaps = 26/252 (10%)
Query: 4 LSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLY 63
++ ++F V+ + I ++V AK +H I + T + TG+ GNKG V +
Sbjct: 471 ITSVTFKTVAIHTLWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFN 530
Query: 64 GYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDI-PNILDHDL--IIWFGDMNFR 120
G + +N HL +R +++ IL + + P + H + WFGD+N+R
Sbjct: 531 GTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLNYR 590
Query: 121 IE--DFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSN 178
++ + + + IK + Y L DQL ++ + F+E + F PTY+F+R +
Sbjct: 591 VDLPTWEAETIIQKIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTR 650
Query: 179 D-------YDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYG 231
D T K P+W DR+LW+ P H + + Y S
Sbjct: 651 DKYAYTKQKATGMKYNLPSWCDRVLWKSY------------PLVH--VVCQSYGSTSDIM 696
Query: 232 ISDHKPVSGTFD 243
SDH PV TF+
Sbjct: 697 TSDHSPVFATFE 708
>gi|64085167 SH2 containing inositol phosphatase isoform a [Homo
sapiens]
Length = 1189
Score = 93.6 bits (231), Expect = 3e-19
Identities = 66/252 (26%), Positives = 111/252 (44%), Gaps = 26/252 (10%)
Query: 4 LSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLY 63
++ ++F V+ + I ++V AK +H I + T + TG+ GNKG V +
Sbjct: 472 ITSVTFKTVAIHTLWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFN 531
Query: 64 GYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDI-PNILDHDL--IIWFGDMNFR 120
G + +N HL +R +++ IL + + P + H + WFGD+N+R
Sbjct: 532 GTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLNYR 591
Query: 121 IE--DFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSN 178
++ + + + IK + Y L DQL ++ + F+E + F PTY+F+R +
Sbjct: 592 VDLPTWEAETIIQKIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTR 651
Query: 179 D-------YDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYG 231
D T K P+W DR+LW+ P H + + Y S
Sbjct: 652 DKYAYTKQKATGMKYNLPSWCDRVLWKSY------------PLVH--VVCQSYGSTSDIM 697
Query: 232 ISDHKPVSGTFD 243
SDH PV TF+
Sbjct: 698 TSDHSPVFATFE 709
>gi|38327539 inositol polyphosphate-5-phosphatase E [Homo sapiens]
Length = 644
Score = 74.7 bits (182), Expect = 1e-13
Identities = 59/213 (27%), Positives = 96/213 (45%), Gaps = 36/213 (16%)
Query: 53 KGGVNICLKLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDH---- 108
KG + I +G I H +RL + R ++ R++P+ +
Sbjct: 404 KGALGISFTFFGTSFLFITSHFTSGDGKVAERLLDYTRTVQALVLP-RNVPDTNPYRSSA 462
Query: 109 -------DLIIWFGDMNFRIEDFGLHFVRESIKNRCYG------GLWEKDQLSIAKKHDP 155
D + WFGD NFR+ G V +++ C G L + DQL +
Sbjct: 463 ADVTTRFDEVFWFGDFNFRLS--GGRTVVDALL--CQGLVVDVPALLQHDQLIREMRKGS 518
Query: 156 LLREFQEGRLLFPPTYKFDRNSNDYDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPAS 215
+ + FQE + F P+YKFD + YD++ K+R P++TDR+L+R + + G P+
Sbjct: 519 IFKGFQEPDIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLYRSRHK---GDICPV---- 571
Query: 216 HFSLSLRGYSSHMTYGISDHKPVSGTFDLELKP 248
YSS SDH+PV G F ++++P
Sbjct: 572 -------SYSSCPGIKTSDHRPVYGLFRVKVRP 597
>gi|119943086 Tax1 (human T-cell leukemia virus type I) binding
protein 1 isoform b [Homo sapiens]
Length = 747
Score = 42.0 bits (97), Expect = 9e-04
Identities = 29/100 (29%), Positives = 40/100 (40%), Gaps = 12/100 (12%)
Query: 273 YSSTSDFPSSPWDWIGLYKVGLRDVNDYVSYAW-------VGDSKVSCSDNLNQVYIDIS 325
Y+ T P DW+G++KVG DY ++ W V S V+C Y
Sbjct: 36 YTLTPYIHPHPKDWVGIFKVGWSTARDYYTFLWSPMPEHYVEGSTVNCVLAFQGYY---- 91
Query: 326 NIPTTEDEFLLCYYSNSLRSVVGISRPFQIPPGSLREDPL 365
+P + EF Y + G S PFQ S E+ L
Sbjct: 92 -LPNDDGEFYQFCYVTHKGEIRGASTPFQFRASSPVEELL 130
>gi|21361682 Tax1 (human T-cell leukemia virus type I) binding
protein 1 isoform a [Homo sapiens]
Length = 789
Score = 42.0 bits (97), Expect = 9e-04
Identities = 29/100 (29%), Positives = 40/100 (40%), Gaps = 12/100 (12%)
Query: 273 YSSTSDFPSSPWDWIGLYKVGLRDVNDYVSYAW-------VGDSKVSCSDNLNQVYIDIS 325
Y+ T P DW+G++KVG DY ++ W V S V+C Y
Sbjct: 36 YTLTPYIHPHPKDWVGIFKVGWSTARDYYTFLWSPMPEHYVEGSTVNCVLAFQGYY---- 91
Query: 326 NIPTTEDEFLLCYYSNSLRSVVGISRPFQIPPGSLREDPL 365
+P + EF Y + G S PFQ S E+ L
Sbjct: 92 -LPNDDGEFYQFCYVTHKGEIRGASTPFQFRASSPVEELL 130
>gi|5031937 calcium binding and coiled-coil domain 2 [Homo sapiens]
Length = 446
Score = 40.4 bits (93), Expect = 0.003
Identities = 26/100 (26%), Positives = 42/100 (42%), Gaps = 3/100 (3%)
Query: 260 EDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDYVSYAWV--GDSKVSCSDNL 317
E + D+ Y+ T F DWIG+++VG + +Y ++ WV + S
Sbjct: 29 EKFYIPGGDVTCHYTFTQHFIPRRKDWIGIFRVGWKTTREYYTFMWVTLPIDLNNKSAKQ 88
Query: 318 NQVYIDISNIPTTEDEFLLCYYSNSLRSVVGISRPFQIPP 357
+V +P ++ + CY V G S PFQ P
Sbjct: 89 QEVQFKAYYLPKDDEYYQFCYVDED-GVVRGASIPFQFRP 127
>gi|14149742 coiled-coil transcriptional coactivator isoform 1 [Homo
sapiens]
Length = 691
Score = 37.4 bits (85), Expect = 0.022
Identities = 24/72 (33%), Positives = 31/72 (43%), Gaps = 2/72 (2%)
Query: 285 DWIGLYKVGLRDVNDYVSYAW--VGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNS 342
DWIG++KV V DY ++ W V +S S V S +P + Y N
Sbjct: 46 DWIGIFKVEAACVRDYHTFVWSSVPESTTDGSPIHTSVQFQASYLPKPGAQLYQFRYVNR 105
Query: 343 LRSVVGISRPFQ 354
V G S PFQ
Sbjct: 106 QGQVCGQSPPFQ 117
>gi|109702906 inositol polyphosphate-5-phosphatase A [Homo sapiens]
Length = 412
Score = 31.6 bits (70), Expect = 1.2
Identities = 22/79 (27%), Positives = 29/79 (36%), Gaps = 20/79 (25%)
Query: 167 FPPTYKFDRNSNDYDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSS 226
FPP+Y + ++ + R PAW DRIL P A L
Sbjct: 323 FPPSYPYSEDARQGEQYMNTRCPAWCDRILMS-------------PSAKELVLRSESEEK 369
Query: 227 HMTYG-------ISDHKPV 238
+TY + DHKPV
Sbjct: 370 VVTYDHIGPNVCMGDHKPV 388
>gi|66392146 RNA U, small nuclear RNA export adaptor
(phosphorylation regulated) [Homo sapiens]
Length = 394
Score = 30.0 bits (66), Expect = 3.5
Identities = 21/67 (31%), Positives = 27/67 (40%), Gaps = 2/67 (2%)
Query: 154 DPLLREFQEGRLLFPPTYKFDRNSNDYDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPP 213
D +R FQ P + R D+SE+ + D LW+ KRQ C P P P
Sbjct: 38 DSAMRAFQNTATACAPVSHY-RAVESVDSSEESFSDSDDDSCLWKRKRQKCFNP-PPKPE 95
Query: 214 ASHFSLS 220
F S
Sbjct: 96 PFQFGQS 102
>gi|62241001 conserved helix-loop-helix ubiquitous kinase [Homo
sapiens]
Length = 745
Score = 29.3 bits (64), Expect = 6.0
Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 5/66 (7%)
Query: 219 LSLRGYSSHMTYGISDHKPVSGTFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSD 278
L L YS MTYGIS K + ++E K + A + V + +E+ +M ++ +
Sbjct: 489 LDLERYSEQMTYGISSEKMLKAWKEMEEKAIHYAEVGV-----IGYLEDQIMSLHAEIME 543
Query: 279 FPSSPW 284
SP+
Sbjct: 544 LQKSPY 549
>gi|27477111 step II splicing factor SLU7 [Homo sapiens]
Length = 586
Score = 29.3 bits (64), Expect = 6.0
Identities = 20/64 (31%), Positives = 32/64 (50%), Gaps = 6/64 (9%)
Query: 151 KKHDPLLREF--QEGRLLF-PPTYKFDRNSNDYDTSEKKRKPAWTDRILWRLKRQPCAGP 207
KKH+ L + +E RLL T + D Y++ + R+P + +R+KRQ P
Sbjct: 520 KKHEKLKKALNAEEARLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQ---RP 576
Query: 208 DTPI 211
D P+
Sbjct: 577 DDPM 580
>gi|223468681 v-rel reticuloendotheliosis viral oncogene homolog A
isoform 2 [Homo sapiens]
Length = 548
Score = 28.9 bits (63), Expect = 7.8
Identities = 18/70 (25%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 157 LREFQEGRLLFPPTYKFDRNSNDYDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASH 216
LR + L P +++ +++D E+KRK + + +K+ P +GP P PP
Sbjct: 269 LRRPSDRELSEPMEFQYLPDTDDRHRIEEKRKRTY-ETFKSIMKKSPFSGPTDPRPPPRR 327
Query: 217 FSLSLRGYSS 226
++ R +S
Sbjct: 328 IAVPSRSSAS 337
>gi|223468676 v-rel reticuloendotheliosis viral oncogene homolog A
isoform 1 [Homo sapiens]
Length = 551
Score = 28.9 bits (63), Expect = 7.8
Identities = 18/70 (25%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 157 LREFQEGRLLFPPTYKFDRNSNDYDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASH 216
LR + L P +++ +++D E+KRK + + +K+ P +GP P PP
Sbjct: 272 LRRPSDRELSEPMEFQYLPDTDDRHRIEEKRKRTY-ETFKSIMKKSPFSGPTDPRPPPRR 330
Query: 217 FSLSLRGYSS 226
++ R +S
Sbjct: 331 IAVPSRSSAS 340
>gi|219521893 coiled-coil transcriptional coactivator isoform 2
[Homo sapiens]
Length = 606
Score = 28.9 bits (63), Expect = 7.8
Identities = 10/21 (47%), Positives = 14/21 (66%)
Query: 285 DWIGLYKVGLRDVNDYVSYAW 305
DWIG++KV V DY ++ W
Sbjct: 46 DWIGIFKVEAACVRDYHTFVW 66
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.140 0.448
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,138,348
Number of Sequences: 37866
Number of extensions: 761234
Number of successful extensions: 1606
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1549
Number of HSP's gapped (non-prelim): 30
length of query: 372
length of database: 18,247,518
effective HSP length: 104
effective length of query: 268
effective length of database: 14,309,454
effective search space: 3834933672
effective search space used: 3834933672
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.