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Search of human proteins with 112789562
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|112789562 interferon, gamma-inducible protein 16 [Homo
sapiens]
(729 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|112789562 interferon, gamma-inducible protein 16 [Homo sapiens] 1450 0.0
gi|41282048 pyrin and HIN domain family, member 1 alpha 2 isofor... 596 e-170
gi|41282051 pyrin and HIN domain family, member 1 beta 2 isoform... 594 e-170
gi|39540514 pyrin and HIN domain family, member 1 alpha 1 isofor... 588 e-168
gi|41282056 pyrin and HIN domain family, member 1 beta 1 isoform... 587 e-167
gi|4505227 myeloid cell nuclear differentiation antigen [Homo sa... 389 e-108
gi|4757734 absent in melanoma 2 [Homo sapiens] 182 1e-45
gi|169161845 PREDICTED: similar to hCG2041495 [Homo sapiens] 124 3e-28
gi|169162310 PREDICTED: similar to hCG2041495 [Homo sapiens] 122 9e-28
gi|169162679 PREDICTED: hypothetical protein LOC646377 [Homo sap... 122 9e-28
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 42 0.002
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 42 0.002
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 42 0.002
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 42 0.002
gi|56118310 nuclear casein kinase and cyclin-dependent kinase su... 42 0.002
gi|155722994 zinc finger CCCH-type containing 3 [Homo sapiens] 42 0.002
gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens] 41 0.003
gi|118421089 chromodomain helicase DNA binding protein 2 isoform... 41 0.005
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 40 0.008
gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho... 39 0.013
gi|33667044 ABI gene family, member 3 (NESH) binding protein [Ho... 39 0.013
gi|157694494 MYB binding protein 1a isoform 1 [Homo sapiens] 39 0.013
gi|157694492 MYB binding protein 1a isoform 2 [Homo sapiens] 39 0.013
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 39 0.013
gi|194363768 homeobox D9 [Homo sapiens] 39 0.017
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 39 0.022
gi|209862789 microtubule associated monoxygenase, calponin and L... 39 0.022
gi|117190342 PHD finger protein 2 [Homo sapiens] 38 0.029
gi|13259510 dynactin 1 isoform 1 [Homo sapiens] 38 0.038
gi|50659104 RAB11 family interacting protein 1 isoform 3 [Homo s... 38 0.038
>gi|112789562 interferon, gamma-inducible protein 16 [Homo sapiens]
Length = 729
Score = 1450 bits (3754), Expect = 0.0
Identities = 729/729 (100%), Positives = 729/729 (100%)
Query: 1 MGKKYKNIVLLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKFRGDA 60
MGKKYKNIVLLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKFRGDA
Sbjct: 1 MGKKYKNIVLLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKFRGDA 60
Query: 61 GLGKLIKIFEDIPTLEDLAETLKKEKLKVKGPALSRKRKKEVDATSPAPSTSSTVKTEGA 120
GLGKLIKIFEDIPTLEDLAETLKKEKLKVKGPALSRKRKKEVDATSPAPSTSSTVKTEGA
Sbjct: 61 GLGKLIKIFEDIPTLEDLAETLKKEKLKVKGPALSRKRKKEVDATSPAPSTSSTVKTEGA 120
Query: 121 EATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSS 180
EATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSS
Sbjct: 121 EATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSS 180
Query: 181 STENPKTVAKCQVTPRRNVLQKRPVIVKVLSTTKPFEYETPEMEKKIMFHATVATQTQFF 240
STENPKTVAKCQVTPRRNVLQKRPVIVKVLSTTKPFEYETPEMEKKIMFHATVATQTQFF
Sbjct: 181 STENPKTVAKCQVTPRRNVLQKRPVIVKVLSTTKPFEYETPEMEKKIMFHATVATQTQFF 240
Query: 241 HVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEESTVSEAGPNQTFEVPNKIINRAKE 300
HVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEESTVSEAGPNQTFEVPNKIINRAKE
Sbjct: 241 HVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEESTVSEAGPNQTFEVPNKIINRAKE 300
Query: 301 TLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIYEIQDDRGKMDVVGTGQCHNIPCEEGD 360
TLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIYEIQDDRGKMDVVGTGQCHNIPCEEGD
Sbjct: 301 TLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIYEIQDDRGKMDVVGTGQCHNIPCEEGD 360
Query: 361 KLQLFCFRLRKKNQMSKLISEMHSFIQIKKKTNPRNNDPKSMKLPQEQRQLPYPSEASTT 420
KLQLFCFRLRKKNQMSKLISEMHSFIQIKKKTNPRNNDPKSMKLPQEQRQLPYPSEASTT
Sbjct: 361 KLQLFCFRLRKKNQMSKLISEMHSFIQIKKKTNPRNNDPKSMKLPQEQRQLPYPSEASTT 420
Query: 421 FPESHLRTPQMPPTTPSSSFFTKKSEDTISKMNDFMRMQILKEGSHFPGPFMTSIGPAES 480
FPESHLRTPQMPPTTPSSSFFTKKSEDTISKMNDFMRMQILKEGSHFPGPFMTSIGPAES
Sbjct: 421 FPESHLRTPQMPPTTPSSSFFTKKSEDTISKMNDFMRMQILKEGSHFPGPFMTSIGPAES 480
Query: 481 HPHTPQMPPSTPSSSFLTTLKPRLKTEPEEVSIEDSAQSDLKEVMVLNATESFVYEPKEQ 540
HPHTPQMPPSTPSSSFLTTLKPRLKTEPEEVSIEDSAQSDLKEVMVLNATESFVYEPKEQ
Sbjct: 481 HPHTPQMPPSTPSSSFLTTLKPRLKTEPEEVSIEDSAQSDLKEVMVLNATESFVYEPKEQ 540
Query: 541 KKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTLVADVNAD 600
KKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTLVADVNAD
Sbjct: 541 KKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTLVADVNAD 600
Query: 601 RNMEIPKGLIRSASVTPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTGKMEV 660
RNMEIPKGLIRSASVTPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTGKMEV
Sbjct: 601 RNMEIPKGLIRSASVTPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTGKMEV 660
Query: 661 VVHGRLTTINCEEGDKLKLTCFELAPKSGNTGELRSVIHSHIKVIKTRKNKKDILNPDSS 720
VVHGRLTTINCEEGDKLKLTCFELAPKSGNTGELRSVIHSHIKVIKTRKNKKDILNPDSS
Sbjct: 661 VVHGRLTTINCEEGDKLKLTCFELAPKSGNTGELRSVIHSHIKVIKTRKNKKDILNPDSS 720
Query: 721 METSPDFFF 729
METSPDFFF
Sbjct: 721 METSPDFFF 729
>gi|41282048 pyrin and HIN domain family, member 1 alpha 2 isoform
[Homo sapiens]
Length = 483
Score = 596 bits (1536), Expect = e-170
Identities = 309/447 (69%), Positives = 362/447 (80%), Gaps = 1/447 (0%)
Query: 1 MGKKYKNIVLLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKFRGDA 60
M YK IVLLKGLEVINDYHFR+VKSLLSNDLKLN KM+EEYDKIQIADLMEEKF GDA
Sbjct: 1 MANNYKKIVLLKGLEVINDYHFRIVKSLLSNDLKLNPKMKEEYDKIQIADLMEEKFPGDA 60
Query: 61 GLGKLIKIFEDIPTLEDLAETLKKEKLKVKGPALSRKRK-KEVDATSPAPSTSSTVKTEG 119
GLGKLI+ F++IPTL DLAETLK+EKLKVKG S+K K KEV +PA + S+ + +G
Sbjct: 61 GLGKLIEFFKEIPTLGDLAETLKREKLKVKGIIPSKKTKQKEVYPATPACTPSNRLTAKG 120
Query: 120 AEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNS 179
AE T G QKRKK ++E+ G K SK+S+EQT+P AGA STAMGRSP P+TS SAPPN+
Sbjct: 121 AEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRSPPPQTSSSAPPNT 180
Query: 180 SSTENPKTVAKCQVTPRRNVLQKRPVIVKVLSTTKPFEYETPEMEKKIMFHATVATQTQF 239
SSTE+ K +A T +N+ ++ P+I VL+ TK F+YE+ E E++ MFHATVATQTQF
Sbjct: 181 SSTESLKPLANRHATASKNIFREDPIIAMVLNATKVFKYESSENEQRRMFHATVATQTQF 240
Query: 240 FHVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEESTVSEAGPNQTFEVPNKIINRAK 299
FHVKVLN +LK KF K+IIIIS+Y + +SLLEVNE S+VSEAGP+QTFEVP II RAK
Sbjct: 241 FHVKVLNINLKRKFIKKRIIIISNYSKRNSLLEVNEASSVSEAGPDQTFEVPKDIIRRAK 300
Query: 300 ETLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIYEIQDDRGKMDVVGTGQCHNIPCEEG 359
+ KI+ILHKQ SG IVYG+FMLH K VN+KTTIYEIQD G M VVG G+CHNIPCE+G
Sbjct: 301 KIPKINILHKQTSGYIVYGLFMLHTKIVNRKTTIYEIQDKTGSMAVVGKGECHNIPCEKG 360
Query: 360 DKLQLFCFRLRKKNQMSKLISEMHSFIQIKKKTNPRNNDPKSMKLPQEQRQLPYPSEAST 419
DKL+LFCFRLRK+ MSKL+SEMHSFIQI+K TN R++D +SM LPQEQ Q P PSEAST
Sbjct: 361 DKLRLFCFRLRKRENMSKLMSEMHSFIQIQKNTNQRSHDSRSMALPQEQSQHPKPSEAST 420
Query: 420 TFPESHLRTPQMPPTTPSSSFFTKKSE 446
T PESHL+TPQMPPTTPSSS FTKK E
Sbjct: 421 TLPESHLKTPQMPPTTPSSSSFTKKDE 447
Score = 177 bits (449), Expect = 3e-44
Identities = 118/298 (39%), Positives = 154/298 (51%), Gaps = 21/298 (7%)
Query: 429 PQMPPTTPSSSFFTKKSEDTISKMN---------DFMRMQILKEGSHFPGPFMTSIGPAE 479
P P TPS+ K +E+T+ R ++ KE + S A
Sbjct: 105 PATPACTPSNRLTAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAM 164
Query: 480 SHPHTPQM----PPSTPSSSFLTTLKPRLKTEPEEVSIEDSAQSDLKEVMVLNATESFVY 535
PQ PP+T S+ L L R T + + ED + MVLNAT+ F Y
Sbjct: 165 GRSPPPQTSSSAPPNTSSTESLKPLANRHATASKNIFREDPIIA-----MVLNATKVFKY 219
Query: 536 EPKE--QKKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTL 593
E E Q++MFHATVAT+ + F VKV NI+LK KF K+II I+NY RN LEV +
Sbjct: 220 ESSENEQRRMFHATVATQTQFFHVKVLNINLKRKFIKKRIIIISNYSKRNSLLEVNEASS 279
Query: 594 VADVNADRNMEIPKGLIRSASVTPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQD 653
V++ D+ E+PK +IR A PKIN L QT G V G+F +H K V + T YEIQD
Sbjct: 280 VSEAGPDQTFEVPKDIIRRAKKIPKINILHKQTSGYIVYGLFMLHTKIVNRKTTIYEIQD 339
Query: 654 NTGKMEVVVHGRLTTINCEEGDKLKLTCFELAPKSGNTGELRSVIHSHIKVIKTRKNK 711
TG M VV G I CE+GDKL+L CF L K N +L S +HS I++ K +
Sbjct: 340 KTGSMAVVGKGECHNIPCEKGDKLRLFCFRLR-KRENMSKLMSEMHSFIQIQKNTNQR 396
Score = 30.4 bits (67), Expect = 6.1
Identities = 20/86 (23%), Positives = 38/86 (44%), Gaps = 1/86 (1%)
Query: 127 QKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPK 186
Q +K + + + + +EQ+Q P P+ A + +P+ + P +SS T+ +
Sbjct: 388 QIQKNTNQRSHDSRSMALPQEQSQHPKPSEASTTLPESHLKTPQMPPTTPSSSSFTKKDE 447
Query: 187 TVAKCQVTPRRNVLQKRPVIVKVLST 212
T Q +P N P + LS+
Sbjct: 448 THPGAQSSP-ANFRITSPTVAPPLSS 472
>gi|41282051 pyrin and HIN domain family, member 1 beta 2 isoform
[Homo sapiens]
Length = 452
Score = 594 bits (1532), Expect = e-170
Identities = 308/448 (68%), Positives = 363/448 (81%), Gaps = 1/448 (0%)
Query: 1 MGKKYKNIVLLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKFRGDA 60
M YK IVLLKGLEVINDYHFR+VKSLLSNDLKLN KM+EEYDKIQIADLMEEKF GDA
Sbjct: 1 MANNYKKIVLLKGLEVINDYHFRIVKSLLSNDLKLNPKMKEEYDKIQIADLMEEKFPGDA 60
Query: 61 GLGKLIKIFEDIPTLEDLAETLKKEKLKVKGPALSRKRK-KEVDATSPAPSTSSTVKTEG 119
GLGKLI+ F++IPTL DLAETLK+EKLKVKG S+K K KEV +PA + S+ + +G
Sbjct: 61 GLGKLIEFFKEIPTLGDLAETLKREKLKVKGIIPSKKTKQKEVYPATPACTPSNRLTAKG 120
Query: 120 AEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNS 179
AE T G QKRKK ++E+ G K SK+S+EQT+P AGA STAMGRSP P+TS SAPPN+
Sbjct: 121 AEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRSPPPQTSSSAPPNT 180
Query: 180 SSTENPKTVAKCQVTPRRNVLQKRPVIVKVLSTTKPFEYETPEMEKKIMFHATVATQTQF 239
SSTE+ K +A T +N+ ++ P+I VL+ TK F+YE+ E E++ MFHATVATQTQF
Sbjct: 181 SSTESLKPLANRHATASKNIFREDPIIAMVLNATKVFKYESSENEQRRMFHATVATQTQF 240
Query: 240 FHVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEESTVSEAGPNQTFEVPNKIINRAK 299
FHVKVLN +LK KF K+IIIIS+Y + +SLLEVNE S+VSEAGP+QTFEVP II RAK
Sbjct: 241 FHVKVLNINLKRKFIKKRIIIISNYSKRNSLLEVNEASSVSEAGPDQTFEVPKDIIRRAK 300
Query: 300 ETLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIYEIQDDRGKMDVVGTGQCHNIPCEEG 359
+ KI+ILHKQ SG IVYG+FMLH K VN+KTTIYEIQD G M VVG G+CHNIPCE+G
Sbjct: 301 KIPKINILHKQTSGYIVYGLFMLHTKIVNRKTTIYEIQDKTGSMAVVGKGECHNIPCEKG 360
Query: 360 DKLQLFCFRLRKKNQMSKLISEMHSFIQIKKKTNPRNNDPKSMKLPQEQRQLPYPSEAST 419
DKL+LFCFRLRK+ MSKL+SEMHSFIQI+K TN R++D +SM LPQEQ Q P PSEAST
Sbjct: 361 DKLRLFCFRLRKRENMSKLMSEMHSFIQIQKNTNQRSHDSRSMALPQEQSQHPKPSEAST 420
Query: 420 TFPESHLRTPQMPPTTPSSSFFTKKSED 447
T PESHL+TPQMPPTTPSSS FTK ++D
Sbjct: 421 TLPESHLKTPQMPPTTPSSSSFTKVTKD 448
Score = 177 bits (449), Expect = 3e-44
Identities = 118/298 (39%), Positives = 154/298 (51%), Gaps = 21/298 (7%)
Query: 429 PQMPPTTPSSSFFTKKSEDTISKMN---------DFMRMQILKEGSHFPGPFMTSIGPAE 479
P P TPS+ K +E+T+ R ++ KE + S A
Sbjct: 105 PATPACTPSNRLTAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAM 164
Query: 480 SHPHTPQM----PPSTPSSSFLTTLKPRLKTEPEEVSIEDSAQSDLKEVMVLNATESFVY 535
PQ PP+T S+ L L R T + + ED + MVLNAT+ F Y
Sbjct: 165 GRSPPPQTSSSAPPNTSSTESLKPLANRHATASKNIFREDPIIA-----MVLNATKVFKY 219
Query: 536 EPKE--QKKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTL 593
E E Q++MFHATVAT+ + F VKV NI+LK KF K+II I+NY RN LEV +
Sbjct: 220 ESSENEQRRMFHATVATQTQFFHVKVLNINLKRKFIKKRIIIISNYSKRNSLLEVNEASS 279
Query: 594 VADVNADRNMEIPKGLIRSASVTPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQD 653
V++ D+ E+PK +IR A PKIN L QT G V G+F +H K V + T YEIQD
Sbjct: 280 VSEAGPDQTFEVPKDIIRRAKKIPKINILHKQTSGYIVYGLFMLHTKIVNRKTTIYEIQD 339
Query: 654 NTGKMEVVVHGRLTTINCEEGDKLKLTCFELAPKSGNTGELRSVIHSHIKVIKTRKNK 711
TG M VV G I CE+GDKL+L CF L K N +L S +HS I++ K +
Sbjct: 340 KTGSMAVVGKGECHNIPCEKGDKLRLFCFRLR-KRENMSKLMSEMHSFIQIQKNTNQR 396
>gi|39540514 pyrin and HIN domain family, member 1 alpha 1 isoform
[Homo sapiens]
Length = 492
Score = 588 bits (1516), Expect = e-168
Identities = 309/456 (67%), Positives = 362/456 (79%), Gaps = 10/456 (2%)
Query: 1 MGKKYKNIVLLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKFRGDA 60
M YK IVLLKGLEVINDYHFR+VKSLLSNDLKLN KM+EEYDKIQIADLMEEKF GDA
Sbjct: 1 MANNYKKIVLLKGLEVINDYHFRIVKSLLSNDLKLNPKMKEEYDKIQIADLMEEKFPGDA 60
Query: 61 GLGKLIKIFEDIPTLEDLAETLKKEKLKV---------KGPALSRKRK-KEVDATSPAPS 110
GLGKLI+ F++IPTL DLAETLK+EKLKV KG S+K K KEV +PA +
Sbjct: 61 GLGKLIEFFKEIPTLGDLAETLKREKLKVANKIESIPVKGIIPSKKTKQKEVYPATPACT 120
Query: 111 TSSTVKTEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPK 170
S+ + +GAE T G QKRKK ++E+ G K SK+S+EQT+P AGA STAMGRSP P+
Sbjct: 121 PSNRLTAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRSPPPQ 180
Query: 171 TSLSAPPNSSSTENPKTVAKCQVTPRRNVLQKRPVIVKVLSTTKPFEYETPEMEKKIMFH 230
TS SAPPN+SSTE+ K +A T +N+ ++ P+I VL+ TK F+YE+ E E++ MFH
Sbjct: 181 TSSSAPPNTSSTESLKPLANRHATASKNIFREDPIIAMVLNATKVFKYESSENEQRRMFH 240
Query: 231 ATVATQTQFFHVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEESTVSEAGPNQTFEV 290
ATVATQTQFFHVKVLN +LK KF K+IIIIS+Y + +SLLEVNE S+VSEAGP+QTFEV
Sbjct: 241 ATVATQTQFFHVKVLNINLKRKFIKKRIIIISNYSKRNSLLEVNEASSVSEAGPDQTFEV 300
Query: 291 PNKIINRAKETLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIYEIQDDRGKMDVVGTGQ 350
P II RAK+ KI+ILHKQ SG IVYG+FMLH K VN+KTTIYEIQD G M VVG G+
Sbjct: 301 PKDIIRRAKKIPKINILHKQTSGYIVYGLFMLHTKIVNRKTTIYEIQDKTGSMAVVGKGE 360
Query: 351 CHNIPCEEGDKLQLFCFRLRKKNQMSKLISEMHSFIQIKKKTNPRNNDPKSMKLPQEQRQ 410
CHNIPCE+GDKL+LFCFRLRK+ MSKL+SEMHSFIQI+K TN R++D +SM LPQEQ Q
Sbjct: 361 CHNIPCEKGDKLRLFCFRLRKRENMSKLMSEMHSFIQIQKNTNQRSHDSRSMALPQEQSQ 420
Query: 411 LPYPSEASTTFPESHLRTPQMPPTTPSSSFFTKKSE 446
P PSEASTT PESHL+TPQMPPTTPSSS FTKK E
Sbjct: 421 HPKPSEASTTLPESHLKTPQMPPTTPSSSSFTKKDE 456
Score = 177 bits (449), Expect = 3e-44
Identities = 118/298 (39%), Positives = 154/298 (51%), Gaps = 21/298 (7%)
Query: 429 PQMPPTTPSSSFFTKKSEDTISKMN---------DFMRMQILKEGSHFPGPFMTSIGPAE 479
P P TPS+ K +E+T+ R ++ KE + S A
Sbjct: 114 PATPACTPSNRLTAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAM 173
Query: 480 SHPHTPQM----PPSTPSSSFLTTLKPRLKTEPEEVSIEDSAQSDLKEVMVLNATESFVY 535
PQ PP+T S+ L L R T + + ED + MVLNAT+ F Y
Sbjct: 174 GRSPPPQTSSSAPPNTSSTESLKPLANRHATASKNIFREDPIIA-----MVLNATKVFKY 228
Query: 536 EPKE--QKKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTL 593
E E Q++MFHATVAT+ + F VKV NI+LK KF K+II I+NY RN LEV +
Sbjct: 229 ESSENEQRRMFHATVATQTQFFHVKVLNINLKRKFIKKRIIIISNYSKRNSLLEVNEASS 288
Query: 594 VADVNADRNMEIPKGLIRSASVTPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQD 653
V++ D+ E+PK +IR A PKIN L QT G V G+F +H K V + T YEIQD
Sbjct: 289 VSEAGPDQTFEVPKDIIRRAKKIPKINILHKQTSGYIVYGLFMLHTKIVNRKTTIYEIQD 348
Query: 654 NTGKMEVVVHGRLTTINCEEGDKLKLTCFELAPKSGNTGELRSVIHSHIKVIKTRKNK 711
TG M VV G I CE+GDKL+L CF L K N +L S +HS I++ K +
Sbjct: 349 KTGSMAVVGKGECHNIPCEKGDKLRLFCFRLR-KRENMSKLMSEMHSFIQIQKNTNQR 405
Score = 30.4 bits (67), Expect = 6.1
Identities = 20/86 (23%), Positives = 38/86 (44%), Gaps = 1/86 (1%)
Query: 127 QKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPK 186
Q +K + + + + +EQ+Q P P+ A + +P+ + P +SS T+ +
Sbjct: 397 QIQKNTNQRSHDSRSMALPQEQSQHPKPSEASTTLPESHLKTPQMPPTTPSSSSFTKKDE 456
Query: 187 TVAKCQVTPRRNVLQKRPVIVKVLST 212
T Q +P N P + LS+
Sbjct: 457 THPGAQSSP-ANFRITSPTVAPPLSS 481
>gi|41282056 pyrin and HIN domain family, member 1 beta 1 isoform
[Homo sapiens]
Length = 461
Score = 587 bits (1512), Expect = e-167
Identities = 308/457 (67%), Positives = 363/457 (79%), Gaps = 10/457 (2%)
Query: 1 MGKKYKNIVLLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKFRGDA 60
M YK IVLLKGLEVINDYHFR+VKSLLSNDLKLN KM+EEYDKIQIADLMEEKF GDA
Sbjct: 1 MANNYKKIVLLKGLEVINDYHFRIVKSLLSNDLKLNPKMKEEYDKIQIADLMEEKFPGDA 60
Query: 61 GLGKLIKIFEDIPTLEDLAETLKKEKLKV---------KGPALSRKRK-KEVDATSPAPS 110
GLGKLI+ F++IPTL DLAETLK+EKLKV KG S+K K KEV +PA +
Sbjct: 61 GLGKLIEFFKEIPTLGDLAETLKREKLKVANKIESIPVKGIIPSKKTKQKEVYPATPACT 120
Query: 111 TSSTVKTEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPK 170
S+ + +GAE T G QKRKK ++E+ G K SK+S+EQT+P AGA STAMGRSP P+
Sbjct: 121 PSNRLTAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAMGRSPPPQ 180
Query: 171 TSLSAPPNSSSTENPKTVAKCQVTPRRNVLQKRPVIVKVLSTTKPFEYETPEMEKKIMFH 230
TS SAPPN+SSTE+ K +A T +N+ ++ P+I VL+ TK F+YE+ E E++ MFH
Sbjct: 181 TSSSAPPNTSSTESLKPLANRHATASKNIFREDPIIAMVLNATKVFKYESSENEQRRMFH 240
Query: 231 ATVATQTQFFHVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEESTVSEAGPNQTFEV 290
ATVATQTQFFHVKVLN +LK KF K+IIIIS+Y + +SLLEVNE S+VSEAGP+QTFEV
Sbjct: 241 ATVATQTQFFHVKVLNINLKRKFIKKRIIIISNYSKRNSLLEVNEASSVSEAGPDQTFEV 300
Query: 291 PNKIINRAKETLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIYEIQDDRGKMDVVGTGQ 350
P II RAK+ KI+ILHKQ SG IVYG+FMLH K VN+KTTIYEIQD G M VVG G+
Sbjct: 301 PKDIIRRAKKIPKINILHKQTSGYIVYGLFMLHTKIVNRKTTIYEIQDKTGSMAVVGKGE 360
Query: 351 CHNIPCEEGDKLQLFCFRLRKKNQMSKLISEMHSFIQIKKKTNPRNNDPKSMKLPQEQRQ 410
CHNIPCE+GDKL+LFCFRLRK+ MSKL+SEMHSFIQI+K TN R++D +SM LPQEQ Q
Sbjct: 361 CHNIPCEKGDKLRLFCFRLRKRENMSKLMSEMHSFIQIQKNTNQRSHDSRSMALPQEQSQ 420
Query: 411 LPYPSEASTTFPESHLRTPQMPPTTPSSSFFTKKSED 447
P PSEASTT PESHL+TPQMPPTTPSSS FTK ++D
Sbjct: 421 HPKPSEASTTLPESHLKTPQMPPTTPSSSSFTKVTKD 457
Score = 177 bits (449), Expect = 3e-44
Identities = 118/298 (39%), Positives = 154/298 (51%), Gaps = 21/298 (7%)
Query: 429 PQMPPTTPSSSFFTKKSEDTISKMN---------DFMRMQILKEGSHFPGPFMTSIGPAE 479
P P TPS+ K +E+T+ R ++ KE + S A
Sbjct: 114 PATPACTPSNRLTAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCSAGASTSTAM 173
Query: 480 SHPHTPQM----PPSTPSSSFLTTLKPRLKTEPEEVSIEDSAQSDLKEVMVLNATESFVY 535
PQ PP+T S+ L L R T + + ED + MVLNAT+ F Y
Sbjct: 174 GRSPPPQTSSSAPPNTSSTESLKPLANRHATASKNIFREDPIIA-----MVLNATKVFKY 228
Query: 536 EPKE--QKKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTL 593
E E Q++MFHATVAT+ + F VKV NI+LK KF K+II I+NY RN LEV +
Sbjct: 229 ESSENEQRRMFHATVATQTQFFHVKVLNINLKRKFIKKRIIIISNYSKRNSLLEVNEASS 288
Query: 594 VADVNADRNMEIPKGLIRSASVTPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQD 653
V++ D+ E+PK +IR A PKIN L QT G V G+F +H K V + T YEIQD
Sbjct: 289 VSEAGPDQTFEVPKDIIRRAKKIPKINILHKQTSGYIVYGLFMLHTKIVNRKTTIYEIQD 348
Query: 654 NTGKMEVVVHGRLTTINCEEGDKLKLTCFELAPKSGNTGELRSVIHSHIKVIKTRKNK 711
TG M VV G I CE+GDKL+L CF L K N +L S +HS I++ K +
Sbjct: 349 KTGSMAVVGKGECHNIPCEKGDKLRLFCFRLR-KRENMSKLMSEMHSFIQIQKNTNQR 405
>gi|4505227 myeloid cell nuclear differentiation antigen [Homo
sapiens]
Length = 407
Score = 389 bits (999), Expect = e-108
Identities = 210/408 (51%), Positives = 282/408 (69%), Gaps = 15/408 (3%)
Query: 1 MGKKYKNIVLLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKFRGDA 60
M +YK I+LLKG E+++DYHF +KSLL+ DL L KM+EEY++I+I DLME+KF+G A
Sbjct: 1 MVNEYKKILLLKGFELMDDYHFTSIKSLLAYDLGLTTKMQEEYNRIKITDLMEKKFQGVA 60
Query: 61 GLGKLIKIFEDIPTLEDLAETLKKEKLKV--------KGPALSRKRKKEVDATSPAPSTS 112
L KLI++ +D+P+L++L L+KEK KV K P + + ++EV +PAP+
Sbjct: 61 CLDKLIELAKDMPSLKNLVNNLRKEKSKVAKKIKTQEKAP-VKKINQEEVGLAAPAPTAR 119
Query: 113 STVKTEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTS 172
+ + +E P AQKRK KEK K +KVS+EQ++PP P+GA S A+ P P+TS
Sbjct: 120 NKLTSEARGRIPVAQKRKTPNKEKTEAKRNKVSQEQSKPPGPSGASTSAAVDHPPLPQTS 179
Query: 173 LSAPPNSSSTENPKTVAKCQVTPRRNVLQKRPVIVKVLSTTKPFEYETPEMEKKIMFHAT 232
S P N+S T N +T A+ QV RRNV Q PV V VL T PF+YE+PE K MFHAT
Sbjct: 180 SSTPSNTSFTPNQETQAQRQVDARRNVPQNDPVTVVVLKATAPFKYESPENGKSTMFHAT 239
Query: 233 VATQTQFFHVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEESTVSEAGPNQTFEVPN 292
VA++TQ+FHVKV + +LKEKF KK+I ISDY E ++E+ E S+VS+ NQ FEVPN
Sbjct: 240 VASKTQYFHVKVFDINLKEKFVRKKVITISDYSECKGVMEIKEASSVSDF--NQNFEVPN 297
Query: 293 KIINRAKETLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIYEIQDDRGKMDVVGTGQCH 352
+II A +T KI L+KQASG +VYG+FML KK+V++K TIYEIQD+ G MDVVG+G+ H
Sbjct: 298 RIIEIANKTPKISQLYKQASGTMVYGLFMLQKKSVHKKNTIYEIQDNTGSMDVVGSGKWH 357
Query: 353 NIPCEEGDKLQLFCFRLRKKNQMSKLISEMHSFIQI----KKKTNPRN 396
NI CE+GDKL+LFC +LR ++ KL+ HSFI++ K K P N
Sbjct: 358 NIKCEKGDKLRLFCLQLRTVDRKLKLVCGSHSFIKVIKAKKNKEGPMN 405
Score = 185 bits (469), Expect = 1e-46
Identities = 133/351 (37%), Positives = 187/351 (53%), Gaps = 27/351 (7%)
Query: 372 KNQMSKLISEMHSFIQIKKKTNPRNNDPKSMKLPQEQRQL--PYPSEASTTFPESHLRTP 429
KN ++ L E ++ KK + P K+ QE+ L P P+ + E+ R P
Sbjct: 76 KNLVNNLRKEKS---KVAKKIKTQEKAPVK-KINQEEVGLAAPAPTARNKLTSEARGRIP 131
Query: 430 QMPPTTPSSSFFTKKSEDTISKMNDFMRMQILKEGSHFPGPFMTSIGPAESHPHTPQMPP 489
T E T +K N ++ +E S PGP S A HP PQ
Sbjct: 132 VAQKRK------TPNKEKTEAKRN-----KVSQEQSKPPGPSGASTSAAVDHPPLPQTSS 180
Query: 490 STPSSSFLTTLKPRLKTEPEEV--SIEDSAQSDLKEVMVLNATESFVYEPKEQKK--MFH 545
STPS+ T+ P +T+ + + + Q+D V+VL AT F YE E K MFH
Sbjct: 181 STPSN---TSFTPNQETQAQRQVDARRNVPQNDPVTVVVLKATAPFKYESPENGKSTMFH 237
Query: 546 ATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTLVADVNADRNMEI 605
ATVA++ + F VKVF+I+LKEKF KK+I I++Y G +E+ + V+D N +N E+
Sbjct: 238 ATVASKTQYFHVKVFDINLKEKFVRKKVITISDYSECKGVMEIKEASSVSDFN--QNFEV 295
Query: 606 PKGLIRSASVTPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTGKMEVVVHGR 665
P +I A+ TPKI+QL Q G+ V G+F + KK+V + T YEIQDNTG M+VV G+
Sbjct: 296 PNRIIEIANKTPKISQLYKQASGTMVYGLFMLQKKSVHKKNTIYEIQDNTGSMDVVGSGK 355
Query: 666 LTTINCEEGDKLKLTCFELAPKSGNTGELRSVIHSHIKVIKTRKNKKDILN 716
I CE+GDKL+L C +L +L HS IKVIK +KNK+ +N
Sbjct: 356 WHNIKCEKGDKLRLFCLQLRTVDRKL-KLVCGSHSFIKVIKAKKNKEGPMN 405
>gi|4757734 absent in melanoma 2 [Homo sapiens]
Length = 343
Score = 182 bits (461), Expect = 1e-45
Identities = 139/398 (34%), Positives = 196/398 (49%), Gaps = 61/398 (15%)
Query: 1 MGKKYKNIVLLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKFRGDA 60
M KYK I+LL GL+ I D K LS++ + ++IQ+A LM + +
Sbjct: 1 MESKYKEILLLTGLDNITDEELDRFKFFLSDEFNIATGKLHTANRIQVATLMIQNAGAVS 60
Query: 61 GLGKLIKIFEDIPTLEDLAETLKKEKLKVKGPALSRKRKKEVDATSPAPSTSSTVKTEGA 120
+ K I+IF+ + + LA+ L++EK KV K+ T P P + A
Sbjct: 61 AVMKTIRIFQKLNYML-LAKRLQEEKEKVD--------KQYKSVTKPKPLSQ-------A 104
Query: 121 EATPGAQK--RKKSTKEKAGPKGSK-VSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAPP 177
E +P A R K++A PK S V EQ Q +
Sbjct: 105 EMSPAASAAIRNDVAKQRAAPKVSPHVKPEQKQMVA------------------------ 140
Query: 178 NSSSTENPKTVAKCQVTPRRNVLQKRPVIVKVLSTTKPFEYETPEMEKKIMFHATVATQT 237
Q R QKR + V VL KPF +ET E K+ MFHATVAT+
Sbjct: 141 --------------QQESIREGFQKRCLPVMVLKAKKPFTFETQE-GKQEMFHATVATEK 185
Query: 238 QFFHVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEESTVSEAGPNQTFEVPNKIINR 297
+FF VKV NT LK+KF K+IIII+ Y + LEVN S V +A +Q VP II +
Sbjct: 186 EFFFVKVFNTLLKDKFIPKRIIIIARYYRHSGFLEVNSASRVLDAESDQKVNVPLNIIRK 245
Query: 298 AKETLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIYEIQDDRGKMDVVGTGQCHNIPCE 357
A ET KI+ L Q G IV G+F++ K T +K ++++ D+ GKM+V+G + C+
Sbjct: 246 AGETPKINTLQTQPLGTIVNGLFVVQKVTEKKKNILFDLSDNTGKMEVLGVRNEDTMKCK 305
Query: 358 EGDKLQLFCFRLRKKNQMSKLISEMHSFIQI---KKKT 392
EGDK++L F L K + +L S +HS I++ KKKT
Sbjct: 306 EGDKVRLTFFTLSKNGEKLQLTSGVHSTIKVIKAKKKT 343
Score = 168 bits (426), Expect = 1e-41
Identities = 98/216 (45%), Positives = 135/216 (62%), Gaps = 7/216 (3%)
Query: 500 LKPRLKTEPEEV-----SIEDSAQSDLKEVMVLNATESFVYEPKEQKK-MFHATVATENE 553
+ P +K E +++ SI + Q VMVL A + F +E +E K+ MFHATVATE E
Sbjct: 127 VSPHVKPEQKQMVAQQESIREGFQKRCLPVMVLKAKKPFTFETQEGKQEMFHATVATEKE 186
Query: 554 VFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTLVADVNADRNMEIPKGLIRSA 613
F VKVFN LK+KF PK+II IA Y +GFLEV + V D +D+ + +P +IR A
Sbjct: 187 FFFVKVFNTLLKDKFIPKRIIIIARYYRHSGFLEVNSASRVLDAESDQKVNVPLNIIRKA 246
Query: 614 SVTPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTGKMEVVVHGRLTTINCEE 673
TPKIN L +Q G+ VNG+F V K + + +++ DNTGKMEV+ T+ C+E
Sbjct: 247 GETPKINTLQTQPLGTIVNGLFVVQKVTEKKKNILFDLSDNTGKMEVLGVRNEDTMKCKE 306
Query: 674 GDKLKLTCFELAPKSGNTGELRSVIHSHIKVIKTRK 709
GDK++LT F L+ K+G +L S +HS IKVIK +K
Sbjct: 307 GDKVRLTFFTLS-KNGEKLQLTSGVHSTIKVIKAKK 341
>gi|169161845 PREDICTED: similar to hCG2041495 [Homo sapiens]
Length = 196
Score = 124 bits (311), Expect = 3e-28
Identities = 77/152 (50%), Positives = 90/152 (59%), Gaps = 24/152 (15%)
Query: 1 MGKKYKNIVLLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKFRGDA 60
M KYKN VLLKGLE INDYHF ++ SLL NDLKLN R+EYDKIQIADLMEEKF GDA
Sbjct: 41 MVSKYKNNVLLKGLEAINDYHFSIINSLLINDLKLNSTRRDEYDKIQIADLMEEKFPGDA 100
Query: 61 GLGKLIKIFEDIPT-LEDLAETLKKEK----------------------LKVKGPALSRK 97
GLGKL + + T DLAETL+K K + KG S+K
Sbjct: 101 GLGKLRTLQRNTNTGRGDLAETLRKVKRSSALGLDVLLFSLLVVNKIKSIPAKGKTSSKK 160
Query: 98 RK-KEVDATSPAPSTSSTVKTEGAEATPGAQK 128
RK ++V T+P +T EG E TP AQ+
Sbjct: 161 RKQRKVGPTTPLATTDKKFTAEGGEETPIAQR 192
>gi|169162310 PREDICTED: similar to hCG2041495 [Homo sapiens]
Length = 196
Score = 122 bits (307), Expect = 9e-28
Identities = 76/152 (50%), Positives = 89/152 (58%), Gaps = 24/152 (15%)
Query: 1 MGKKYKNIVLLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKFRGDA 60
M KYKN VLLKGLE INDYHF ++ SLL NDLKLN R+EYDKIQIADLMEEKF GDA
Sbjct: 41 MVSKYKNNVLLKGLEAINDYHFSIINSLLINDLKLNSTRRDEYDKIQIADLMEEKFPGDA 100
Query: 61 GLGKLIKIFEDIPT-LEDLAETLKKEK----------------------LKVKGPALSRK 97
G GKL + + T DLAETL+K K + KG S+K
Sbjct: 101 GFGKLRTLQRNTNTGRGDLAETLRKVKRSSALGLDVLLFSLLVVNKIKSIPAKGKTSSKK 160
Query: 98 RK-KEVDATSPAPSTSSTVKTEGAEATPGAQK 128
RK ++V T+P +T EG E TP AQ+
Sbjct: 161 RKQRKVGPTTPLATTDKKFTAEGGEETPIAQR 192
>gi|169162679 PREDICTED: hypothetical protein LOC646377 [Homo
sapiens]
Length = 196
Score = 122 bits (307), Expect = 9e-28
Identities = 76/152 (50%), Positives = 89/152 (58%), Gaps = 24/152 (15%)
Query: 1 MGKKYKNIVLLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKFRGDA 60
M KYKN VLLKGLE INDYHF ++ SLL NDLKLN R+EYDKIQIADLMEEKF GDA
Sbjct: 41 MVSKYKNNVLLKGLEAINDYHFSIINSLLINDLKLNSTRRDEYDKIQIADLMEEKFPGDA 100
Query: 61 GLGKLIKIFEDIPT-LEDLAETLKKEK----------------------LKVKGPALSRK 97
G GKL + + T DLAETL+K K + KG S+K
Sbjct: 101 GFGKLRTLQRNTNTGRGDLAETLRKVKRSSALGLDVLLFSLLVVNKIKSIPAKGKTSSKK 160
Query: 98 RK-KEVDATSPAPSTSSTVKTEGAEATPGAQK 128
RK ++V T+P +T EG E TP AQ+
Sbjct: 161 RKQRKVGPTTPLATTDKKFTAEGGEETPIAQR 192
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 42.0 bits (97), Expect = 0.002
Identities = 34/134 (25%), Positives = 55/134 (41%), Gaps = 20/134 (14%)
Query: 73 PTLEDLAETLKKEKLKVKGPALSRKRK------KEVDATSPAPSTSSTVK---------- 116
PT + LA+ K + KGPAL+ ++ KE +T+P T +T+K
Sbjct: 189 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 248
Query: 117 ---TEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSL 173
T+ A TP + +TKE A + + T+ P+P + + P+P T
Sbjct: 249 PTTTKSAPTTP-KEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 307
Query: 174 SAPPNSSSTENPKT 187
P + P T
Sbjct: 308 KPAPTTPKEPAPTT 321
Score = 37.7 bits (86), Expect = 0.038
Identities = 35/146 (23%), Positives = 50/146 (34%), Gaps = 11/146 (7%)
Query: 70 EDIPTLEDLAETLKKEKLKVKGPALSRKRKKEVDATSPAPSTSSTVKTEGAEATPGAQKR 129
E PT ++ A T KE + KE T+P +T K E +P K
Sbjct: 332 EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTK----EPSPTTPKE 387
Query: 130 KKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPKTVA 189
T K+ P T+ P+P + + PSP T+ P + P T
Sbjct: 388 PAPTTTKSAPT-------TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK 440
Query: 190 KCQVTPRRNVLQKRPVIVKVLSTTKP 215
K T + P +T KP
Sbjct: 441 KPAPTTPKEPAPTTPKEPAPTTTKKP 466
Score = 36.2 bits (82), Expect = 0.11
Identities = 38/151 (25%), Positives = 56/151 (37%), Gaps = 12/151 (7%)
Query: 70 EDIPTLEDLAETLKKEKLKV--KGPALSRKRKKEVDATS-PAPSTSSTVKTEGAEATPGA 126
E PT A T KE K PA + ++ T PAP+T+ + T E P
Sbjct: 246 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 305
Query: 127 QKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPK 186
K+ T K + + + ++ P +P +T +PK P + PK
Sbjct: 306 PKKPAPTTPK---EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK 362
Query: 187 TVAKCQVTPRRNVLQKRPVIVKVLSTTKPFE 217
A TP+ + P K S T P E
Sbjct: 363 EPA--PTTPK----EPAPTTTKEPSPTTPKE 387
Score = 35.8 bits (81), Expect = 0.14
Identities = 34/141 (24%), Positives = 50/141 (35%), Gaps = 10/141 (7%)
Query: 73 PTLEDLAETLKKEKLKVKGPALSRKRKKEVDATSPAPSTSSTVKTEGAEATPGAQKRKKS 132
P+L ++T K+ L V + KE T+ ST KT A+ T +K
Sbjct: 128 PSLPPNSDTSKETSLTVNKE--TTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK---- 181
Query: 133 TKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPKTVAKCQ 192
T K SKV + T G + + P+P T + P T+
Sbjct: 182 TSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP 241
Query: 193 VTPRRNVLQKRPVIVKVLSTT 213
TP+ + P K TT
Sbjct: 242 TTPK----EPAPTTTKSAPTT 258
Score = 34.7 bits (78), Expect = 0.32
Identities = 35/127 (27%), Positives = 48/127 (37%), Gaps = 21/127 (16%)
Query: 392 TNPRNNDPKSMKLPQEQRQLPYPS---EASTTFPESHL-RTPQMP-PTTPSSSFFTKKSE 446
T P+ P + K P + P P+ E + T P+ TP+ P PTTP T E
Sbjct: 320 TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKE 379
Query: 447 DTISKMNDFMRMQILKEGSHFPGPFMTSIGPA---ESHPHTPQMPPSTPSSSFLTTLKPR 503
+ + + P P T P E P T + P+TP TT K
Sbjct: 380 PSPTTPKE-------------PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP 426
Query: 504 LKTEPEE 510
T P+E
Sbjct: 427 APTTPKE 433
Score = 33.9 bits (76), Expect = 0.55
Identities = 35/136 (25%), Positives = 53/136 (38%), Gaps = 19/136 (13%)
Query: 390 KKTNPRNNDPKSMKLPQEQRQLPYPSEASTTFPESHLRTPQMP-PTTPSSSFFTKKSEDT 448
KK P + + P++ A TT E TP+ P PTTP ++ E
Sbjct: 488 KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA 547
Query: 449 ISKMNDFMRMQILKEGSHFPGPFMTSIGPAESHPHTP-QMPPSTPSSSFLTTLKPRLKTE 507
+ + P P P E P TP + P+TP + TTLK T
Sbjct: 548 PTTPKE-------------PAPTT----PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTT 590
Query: 508 PEEVSIEDSAQSDLKE 523
P++ + ++ A + KE
Sbjct: 591 PKKPAPKELAPTTTKE 606
Score = 33.5 bits (75), Expect = 0.72
Identities = 29/126 (23%), Positives = 44/126 (34%), Gaps = 2/126 (1%)
Query: 74 TLEDLAETLKKEKLKVKGPALSRKRKKEVDATSPAPST-SSTVKTEGAEATPGAQKRKKS 132
TL++ A T K+ + + K PAP+T T T E P K
Sbjct: 582 TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP 641
Query: 133 TKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPKTVAK-C 191
T K + T P PA ++ + P+ TS P + P T +
Sbjct: 642 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA 701
Query: 192 QVTPRR 197
TP++
Sbjct: 702 PTTPKK 707
Score = 33.1 bits (74), Expect = 0.94
Identities = 78/365 (21%), Positives = 125/365 (34%), Gaps = 56/365 (15%)
Query: 100 KEVDATSPAPSTSSTVKTEGAEATPGAQKRKKSTKEKA-----GP------KGSKVSEEQ 148
KE T+P + +T+K E A TP +K + KE A GP K + + ++
Sbjct: 637 KEPAPTTPKGTAPTTLK-EPAPTTP----KKPAPKELAPTTTKGPTSTTSDKPAPTTPKE 691
Query: 149 TQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPKTVAKCQVTPRRNVLQKRPVIVK 208
T P +P +T + P+P T + PP +S P T T + K P
Sbjct: 692 TAPTTPKEPAPTTP--KKPAPTTPETPPPTTSEVSTPTT------TKEPTTIHKSP---- 739
Query: 209 VLSTTKPFEYETPE-MEKKIMFHATVATQTQFFHVKVLNTSLKEKFNGKKIIIISDYLEY 267
ST + TP+ +E T+T + T+ K+K +
Sbjct: 740 DESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER----------- 788
Query: 268 DSLLEVNEESTVSEAGPNQTFEVPNKIINRAKETLKIDILHKQASGNIVYGVFMLHKKTV 327
L E +T + +T K + + + L T+
Sbjct: 789 -DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTL 847
Query: 328 NQKTTIYEIQDDRGKMDVVGTGQCHNIPCEEG---DKLQLFCFRLRKKNQMSKLISEMHS 384
K T + + T + N P E D+ K + +K + S
Sbjct: 848 APKVTTTK--------KTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTS 899
Query: 385 FIQIKKKTNPRNNDPKSMKLPQEQRQLPYPSEASTTFPESHLRTPQMPPTTPSSSF--FT 442
K KT PR PK+ P++ ++ E+ L+T P TP+S
Sbjct: 900 --TKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVN 957
Query: 443 KKSED 447
KSED
Sbjct: 958 PKSED 962
Score = 32.3 bits (72), Expect = 1.6
Identities = 34/122 (27%), Positives = 46/122 (37%), Gaps = 25/122 (20%)
Query: 390 KKTNPRNNDPKSMKLPQEQRQLPYPSEASTTFPESHLRTPQMP-PTTPSSSFFTKKSEDT 448
+KT+ ++ P S L + P P +A TT L TP+ P PTTP T E T
Sbjct: 180 EKTSAKDLAPTSKVLAK-----PTP-KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 233
Query: 449 ISKMNDFMRMQILKEGSHFPGPFMTSIGPAESHPHTPQMPPSTPSSSFLTTLKPRLKTEP 508
+ + P E P T + P+TP TT K T P
Sbjct: 234 PTTIKS------------------APTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP 275
Query: 509 EE 510
+E
Sbjct: 276 KE 277
Score = 32.3 bits (72), Expect = 1.6
Identities = 52/225 (23%), Positives = 72/225 (32%), Gaps = 26/225 (11%)
Query: 392 TNPRNNDPKSMK-----LPQEQRQLPYPSEASTTFPESHLRTPQMPPTTPSSSFFTKKSE 446
T P+ P + K P+E A TT E TP+ P + TK
Sbjct: 618 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPT 677
Query: 447 DTIS-KMNDFMRMQILKEGSHFPGPFMTSIGPAESHPHTPQMPPSTPSSSFLTTLK---- 501
T S K + P P T PA + P TP PP+T S TT K
Sbjct: 678 STTSDKPAPTTPKETAPTTPKEPAP-TTPKKPAPTTPETP--PPTTSEVSTPTTTKEPTT 734
Query: 502 ---------PRLKTEPEEVSIEDSAQS----DLKEVMVLNATESFVYEPKEQKKMFHATV 548
P L EP ++E+S + K + + K ++ T
Sbjct: 735 IHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTP 794
Query: 549 ATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTL 593
T ++ EK T KI A V + PF +
Sbjct: 795 ETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKI 839
Score = 32.0 bits (71), Expect = 2.1
Identities = 39/150 (26%), Positives = 57/150 (38%), Gaps = 17/150 (11%)
Query: 392 TNPRNNDPKSMKLPQEQRQLPYPSEASTTFPESHLRTPQMPPTTPSSSFFTKKSEDTISK 451
T P+ P + P+E A TT E TP+ P + TK+ T
Sbjct: 557 TTPKEPAPTT---PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD 613
Query: 452 MNDFMRMQILKEGSHFP-GPFMTSIGPAESHPHTPQMP-PSTPSSSFLTTLKPRLKTEPE 509
K P G T+ P E P TP+ P P+TP + TTLK T P+
Sbjct: 614 ----------KPAPTTPKGTAPTT--PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK 661
Query: 510 EVSIEDSAQSDLKEVMVLNATESFVYEPKE 539
+ + ++ A + K + + PKE
Sbjct: 662 KPAPKELAPTTTKGPTSTTSDKPAPTTPKE 691
Score = 31.6 bits (70), Expect = 2.7
Identities = 40/141 (28%), Positives = 56/141 (39%), Gaps = 13/141 (9%)
Query: 392 TNPRNNDPKSMKLPQEQRQLPYPS---EASTTFPESHLRTPQMP-PTTPS--SSFFTKKS 445
T P+ P ++K + P P+ A TT E T + P PTTP + TK+
Sbjct: 227 TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEP 286
Query: 446 EDTISKMNDFMRMQILKEGSHFPGPFMTSIGPAESHPHTPQMP-PSTPSSSFLTTLKPRL 504
T +K + P P P E P TP+ P P+TP TT +P
Sbjct: 287 APTTTKSAPTTPKEPAPTTPKKPAPTT----PKEPAPTTPKEPTPTTPKEPAPTTKEPAP 342
Query: 505 KT--EPEEVSIEDSAQSDLKE 523
T EP + + A + KE
Sbjct: 343 TTPKEPAPTAPKKPAPTTPKE 363
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 42.0 bits (97), Expect = 0.002
Identities = 34/134 (25%), Positives = 55/134 (41%), Gaps = 20/134 (14%)
Query: 73 PTLEDLAETLKKEKLKVKGPALSRKRK------KEVDATSPAPSTSSTVK---------- 116
PT + LA+ K + KGPAL+ ++ KE +T+P T +T+K
Sbjct: 230 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 289
Query: 117 ---TEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSL 173
T+ A TP + +TKE A + + T+ P+P + + P+P T
Sbjct: 290 PTTTKSAPTTP-KEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 348
Query: 174 SAPPNSSSTENPKT 187
P + P T
Sbjct: 349 KPAPTTPKEPAPTT 362
Score = 37.7 bits (86), Expect = 0.038
Identities = 35/146 (23%), Positives = 50/146 (34%), Gaps = 11/146 (7%)
Query: 70 EDIPTLEDLAETLKKEKLKVKGPALSRKRKKEVDATSPAPSTSSTVKTEGAEATPGAQKR 129
E PT ++ A T KE + KE T+P +T K E +P K
Sbjct: 373 EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTK----EPSPTTPKE 428
Query: 130 KKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPKTVA 189
T K+ P T+ P+P + + PSP T+ P + P T
Sbjct: 429 PAPTTTKSAPT-------TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK 481
Query: 190 KCQVTPRRNVLQKRPVIVKVLSTTKP 215
K T + P +T KP
Sbjct: 482 KPAPTTPKEPAPTTPKEPAPTTTKKP 507
Score = 36.2 bits (82), Expect = 0.11
Identities = 38/151 (25%), Positives = 56/151 (37%), Gaps = 12/151 (7%)
Query: 70 EDIPTLEDLAETLKKEKLKV--KGPALSRKRKKEVDATS-PAPSTSSTVKTEGAEATPGA 126
E PT A T KE K PA + ++ T PAP+T+ + T E P
Sbjct: 287 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 346
Query: 127 QKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPK 186
K+ T K + + + ++ P +P +T +PK P + PK
Sbjct: 347 PKKPAPTTPK---EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK 403
Query: 187 TVAKCQVTPRRNVLQKRPVIVKVLSTTKPFE 217
A TP+ + P K S T P E
Sbjct: 404 EPA--PTTPK----EPAPTTTKEPSPTTPKE 428
Score = 35.8 bits (81), Expect = 0.14
Identities = 34/141 (24%), Positives = 50/141 (35%), Gaps = 10/141 (7%)
Query: 73 PTLEDLAETLKKEKLKVKGPALSRKRKKEVDATSPAPSTSSTVKTEGAEATPGAQKRKKS 132
P+L ++T K+ L V + KE T+ ST KT A+ T +K
Sbjct: 169 PSLPPNSDTSKETSLTVNKE--TTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK---- 222
Query: 133 TKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPKTVAKCQ 192
T K SKV + T G + + P+P T + P T+
Sbjct: 223 TSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP 282
Query: 193 VTPRRNVLQKRPVIVKVLSTT 213
TP+ + P K TT
Sbjct: 283 TTPK----EPAPTTTKSAPTT 299
Score = 34.7 bits (78), Expect = 0.32
Identities = 35/127 (27%), Positives = 48/127 (37%), Gaps = 21/127 (16%)
Query: 392 TNPRNNDPKSMKLPQEQRQLPYPS---EASTTFPESHL-RTPQMP-PTTPSSSFFTKKSE 446
T P+ P + K P + P P+ E + T P+ TP+ P PTTP T E
Sbjct: 361 TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKE 420
Query: 447 DTISKMNDFMRMQILKEGSHFPGPFMTSIGPA---ESHPHTPQMPPSTPSSSFLTTLKPR 503
+ + + P P T P E P T + P+TP TT K
Sbjct: 421 PSPTTPKE-------------PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP 467
Query: 504 LKTEPEE 510
T P+E
Sbjct: 468 APTTPKE 474
Score = 33.9 bits (76), Expect = 0.55
Identities = 35/136 (25%), Positives = 53/136 (38%), Gaps = 19/136 (13%)
Query: 390 KKTNPRNNDPKSMKLPQEQRQLPYPSEASTTFPESHLRTPQMP-PTTPSSSFFTKKSEDT 448
KK P + + P++ A TT E TP+ P PTTP ++ E
Sbjct: 529 KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA 588
Query: 449 ISKMNDFMRMQILKEGSHFPGPFMTSIGPAESHPHTP-QMPPSTPSSSFLTTLKPRLKTE 507
+ + P P P E P TP + P+TP + TTLK T
Sbjct: 589 PTTPKE-------------PAPTT----PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTT 631
Query: 508 PEEVSIEDSAQSDLKE 523
P++ + ++ A + KE
Sbjct: 632 PKKPAPKELAPTTTKE 647
Score = 33.5 bits (75), Expect = 0.72
Identities = 29/126 (23%), Positives = 44/126 (34%), Gaps = 2/126 (1%)
Query: 74 TLEDLAETLKKEKLKVKGPALSRKRKKEVDATSPAPST-SSTVKTEGAEATPGAQKRKKS 132
TL++ A T K+ + + K PAP+T T T E P K
Sbjct: 623 TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP 682
Query: 133 TKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPKTVAK-C 191
T K + T P PA ++ + P+ TS P + P T +
Sbjct: 683 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA 742
Query: 192 QVTPRR 197
TP++
Sbjct: 743 PTTPKK 748
Score = 33.1 bits (74), Expect = 0.94
Identities = 78/365 (21%), Positives = 125/365 (34%), Gaps = 56/365 (15%)
Query: 100 KEVDATSPAPSTSSTVKTEGAEATPGAQKRKKSTKEKA-----GP------KGSKVSEEQ 148
KE T+P + +T+K E A TP +K + KE A GP K + + ++
Sbjct: 678 KEPAPTTPKGTAPTTLK-EPAPTTP----KKPAPKELAPTTTKGPTSTTSDKPAPTTPKE 732
Query: 149 TQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPKTVAKCQVTPRRNVLQKRPVIVK 208
T P +P +T + P+P T + PP +S P T T + K P
Sbjct: 733 TAPTTPKEPAPTTP--KKPAPTTPETPPPTTSEVSTPTT------TKEPTTIHKSP---- 780
Query: 209 VLSTTKPFEYETPE-MEKKIMFHATVATQTQFFHVKVLNTSLKEKFNGKKIIIISDYLEY 267
ST + TP+ +E T+T + T+ K+K +
Sbjct: 781 DESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER----------- 829
Query: 268 DSLLEVNEESTVSEAGPNQTFEVPNKIINRAKETLKIDILHKQASGNIVYGVFMLHKKTV 327
L E +T + +T K + + + L T+
Sbjct: 830 -DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTL 888
Query: 328 NQKTTIYEIQDDRGKMDVVGTGQCHNIPCEEG---DKLQLFCFRLRKKNQMSKLISEMHS 384
K T + + T + N P E D+ K + +K + S
Sbjct: 889 APKVTTTK--------KTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTS 940
Query: 385 FIQIKKKTNPRNNDPKSMKLPQEQRQLPYPSEASTTFPESHLRTPQMPPTTPSSSF--FT 442
K KT PR PK+ P++ ++ E+ L+T P TP+S
Sbjct: 941 --TKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVN 998
Query: 443 KKSED 447
KSED
Sbjct: 999 PKSED 1003
Score = 32.3 bits (72), Expect = 1.6
Identities = 34/122 (27%), Positives = 46/122 (37%), Gaps = 25/122 (20%)
Query: 390 KKTNPRNNDPKSMKLPQEQRQLPYPSEASTTFPESHLRTPQMP-PTTPSSSFFTKKSEDT 448
+KT+ ++ P S L + P P +A TT L TP+ P PTTP T E T
Sbjct: 221 EKTSAKDLAPTSKVLAK-----PTP-KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 274
Query: 449 ISKMNDFMRMQILKEGSHFPGPFMTSIGPAESHPHTPQMPPSTPSSSFLTTLKPRLKTEP 508
+ + P E P T + P+TP TT K T P
Sbjct: 275 PTTIKS------------------APTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP 316
Query: 509 EE 510
+E
Sbjct: 317 KE 318
Score = 32.3 bits (72), Expect = 1.6
Identities = 52/225 (23%), Positives = 72/225 (32%), Gaps = 26/225 (11%)
Query: 392 TNPRNNDPKSMK-----LPQEQRQLPYPSEASTTFPESHLRTPQMPPTTPSSSFFTKKSE 446
T P+ P + K P+E A TT E TP+ P + TK
Sbjct: 659 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPT 718
Query: 447 DTIS-KMNDFMRMQILKEGSHFPGPFMTSIGPAESHPHTPQMPPSTPSSSFLTTLK---- 501
T S K + P P T PA + P TP PP+T S TT K
Sbjct: 719 STTSDKPAPTTPKETAPTTPKEPAP-TTPKKPAPTTPETP--PPTTSEVSTPTTTKEPTT 775
Query: 502 ---------PRLKTEPEEVSIEDSAQS----DLKEVMVLNATESFVYEPKEQKKMFHATV 548
P L EP ++E+S + K + + K ++ T
Sbjct: 776 IHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTP 835
Query: 549 ATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTL 593
T ++ EK T KI A V + PF +
Sbjct: 836 ETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKI 880
Score = 32.0 bits (71), Expect = 2.1
Identities = 39/150 (26%), Positives = 57/150 (38%), Gaps = 17/150 (11%)
Query: 392 TNPRNNDPKSMKLPQEQRQLPYPSEASTTFPESHLRTPQMPPTTPSSSFFTKKSEDTISK 451
T P+ P + P+E A TT E TP+ P + TK+ T
Sbjct: 598 TTPKEPAPTT---PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD 654
Query: 452 MNDFMRMQILKEGSHFP-GPFMTSIGPAESHPHTPQMP-PSTPSSSFLTTLKPRLKTEPE 509
K P G T+ P E P TP+ P P+TP + TTLK T P+
Sbjct: 655 ----------KPAPTTPKGTAPTT--PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK 702
Query: 510 EVSIEDSAQSDLKEVMVLNATESFVYEPKE 539
+ + ++ A + K + + PKE
Sbjct: 703 KPAPKELAPTTTKGPTSTTSDKPAPTTPKE 732
Score = 31.6 bits (70), Expect = 2.7
Identities = 40/141 (28%), Positives = 56/141 (39%), Gaps = 13/141 (9%)
Query: 392 TNPRNNDPKSMKLPQEQRQLPYPS---EASTTFPESHLRTPQMP-PTTPS--SSFFTKKS 445
T P+ P ++K + P P+ A TT E T + P PTTP + TK+
Sbjct: 268 TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEP 327
Query: 446 EDTISKMNDFMRMQILKEGSHFPGPFMTSIGPAESHPHTPQMP-PSTPSSSFLTTLKPRL 504
T +K + P P P E P TP+ P P+TP TT +P
Sbjct: 328 APTTTKSAPTTPKEPAPTTPKKPAPTT----PKEPAPTTPKEPTPTTPKEPAPTTKEPAP 383
Query: 505 KT--EPEEVSIEDSAQSDLKE 523
T EP + + A + KE
Sbjct: 384 TTPKEPAPTAPKKPAPTTPKE 404
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 42.0 bits (97), Expect = 0.002
Identities = 34/134 (25%), Positives = 55/134 (41%), Gaps = 20/134 (14%)
Query: 73 PTLEDLAETLKKEKLKVKGPALSRKRK------KEVDATSPAPSTSSTVK---------- 116
PT + LA+ K + KGPAL+ ++ KE +T+P T +T+K
Sbjct: 282 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 341
Query: 117 ---TEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSL 173
T+ A TP + +TKE A + + T+ P+P + + P+P T
Sbjct: 342 PTTTKSAPTTP-KEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 400
Query: 174 SAPPNSSSTENPKT 187
P + P T
Sbjct: 401 KPAPTTPKEPAPTT 414
Score = 38.5 bits (88), Expect = 0.022
Identities = 97/428 (22%), Positives = 150/428 (35%), Gaps = 59/428 (13%)
Query: 106 SPAPS-TSSTVK--TEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTA 162
+P PS S T+K T+ + P +K KK + + + VSE Q S + + S+
Sbjct: 78 APPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSST 137
Query: 163 MGRSPSPKTSLS---APPNSSSTENPKTVAKCQVTPRRNVLQKRPVIVKVLSTTKPFEYE 219
+ + S K S + +N K K + TP K PV+ + S +++
Sbjct: 138 IRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTP------KPPVVDEAGSGLDNGDFK 191
Query: 220 TPEMEKKIMFHATVATQTQFFHVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEESTV 279
+ H V+T + K +N N S + ++ +E E +T
Sbjct: 192 VTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTT 251
Query: 280 SEAGPNQTFEVPNKIINRAKETLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIYEIQDD 339
++ QT + AKET I+ K ++ ++ +L K T +TT
Sbjct: 252 NK----QTSTDGKEKTTSAKETQSIE---KTSAKDLAPTSKVLAKPTPKAETTT------ 298
Query: 340 RGKMDVVGTGQCHNIPCEEGDKLQLFCFRLRKKNQMSKLISEMHSFIQIKKKTNPRNNDP 399
G P E K S E T P+ P
Sbjct: 299 --------KGPALTTPKEPTPTTP--------KEPASTTPKEPTPTTIKSAPTTPKEPAP 342
Query: 400 KSMKLPQEQRQLPYPSEASTTFPESHLRTPQMP-PTTPSSSFFTKKSEDTISKMNDFMRM 458
+ K + P P TT E TP+ P PTT TK+ T +K
Sbjct: 343 TTTKSAPTTPKEPAP----TTTKEPAPTTPKEPAPTT------TKEPAPTTTKSAPTTPK 392
Query: 459 QILKEGSHFPGPFMTSIGPAESHPHTPQMP-PSTPSSSFLTTLKPRLKT--EPEEVSIED 515
+ P P P E P TP+ P P+TP TT +P T EP + +
Sbjct: 393 EPAPTTPKKPAPTT----PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKK 448
Query: 516 SAQSDLKE 523
A + KE
Sbjct: 449 PAPTTPKE 456
Score = 37.7 bits (86), Expect = 0.038
Identities = 35/146 (23%), Positives = 50/146 (34%), Gaps = 11/146 (7%)
Query: 70 EDIPTLEDLAETLKKEKLKVKGPALSRKRKKEVDATSPAPSTSSTVKTEGAEATPGAQKR 129
E PT ++ A T KE + KE T+P +T K E +P K
Sbjct: 425 EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTK----EPSPTTPKE 480
Query: 130 KKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPKTVA 189
T K+ P T+ P+P + + PSP T+ P + P T
Sbjct: 481 PAPTTTKSAPT-------TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK 533
Query: 190 KCQVTPRRNVLQKRPVIVKVLSTTKP 215
K T + P +T KP
Sbjct: 534 KPAPTTPKEPAPTTPKEPAPTTTKKP 559
Score = 36.2 bits (82), Expect = 0.11
Identities = 38/151 (25%), Positives = 56/151 (37%), Gaps = 12/151 (7%)
Query: 70 EDIPTLEDLAETLKKEKLKV--KGPALSRKRKKEVDATS-PAPSTSSTVKTEGAEATPGA 126
E PT A T KE K PA + ++ T PAP+T+ + T E P
Sbjct: 339 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 398
Query: 127 QKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPK 186
K+ T K + + + ++ P +P +T +PK P + PK
Sbjct: 399 PKKPAPTTPK---EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK 455
Query: 187 TVAKCQVTPRRNVLQKRPVIVKVLSTTKPFE 217
A TP+ + P K S T P E
Sbjct: 456 EPA--PTTPK----EPAPTTTKEPSPTTPKE 480
Score = 35.8 bits (81), Expect = 0.14
Identities = 34/141 (24%), Positives = 50/141 (35%), Gaps = 10/141 (7%)
Query: 73 PTLEDLAETLKKEKLKVKGPALSRKRKKEVDATSPAPSTSSTVKTEGAEATPGAQKRKKS 132
P+L ++T K+ L V + KE T+ ST KT A+ T +K
Sbjct: 221 PSLPPNSDTSKETSLTVNKE--TTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK---- 274
Query: 133 TKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPKTVAKCQ 192
T K SKV + T G + + P+P T + P T+
Sbjct: 275 TSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP 334
Query: 193 VTPRRNVLQKRPVIVKVLSTT 213
TP+ + P K TT
Sbjct: 335 TTPK----EPAPTTTKSAPTT 351
Score = 34.7 bits (78), Expect = 0.32
Identities = 35/127 (27%), Positives = 48/127 (37%), Gaps = 21/127 (16%)
Query: 392 TNPRNNDPKSMKLPQEQRQLPYPS---EASTTFPESHL-RTPQMP-PTTPSSSFFTKKSE 446
T P+ P + K P + P P+ E + T P+ TP+ P PTTP T E
Sbjct: 413 TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKE 472
Query: 447 DTISKMNDFMRMQILKEGSHFPGPFMTSIGPA---ESHPHTPQMPPSTPSSSFLTTLKPR 503
+ + + P P T P E P T + P+TP TT K
Sbjct: 473 PSPTTPKE-------------PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP 519
Query: 504 LKTEPEE 510
T P+E
Sbjct: 520 APTTPKE 526
Score = 33.9 bits (76), Expect = 0.55
Identities = 35/136 (25%), Positives = 53/136 (38%), Gaps = 19/136 (13%)
Query: 390 KKTNPRNNDPKSMKLPQEQRQLPYPSEASTTFPESHLRTPQMP-PTTPSSSFFTKKSEDT 448
KK P + + P++ A TT E TP+ P PTTP ++ E
Sbjct: 581 KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA 640
Query: 449 ISKMNDFMRMQILKEGSHFPGPFMTSIGPAESHPHTP-QMPPSTPSSSFLTTLKPRLKTE 507
+ + P P P E P TP + P+TP + TTLK T
Sbjct: 641 PTTPKE-------------PAPTT----PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTT 683
Query: 508 PEEVSIEDSAQSDLKE 523
P++ + ++ A + KE
Sbjct: 684 PKKPAPKELAPTTTKE 699
Score = 33.5 bits (75), Expect = 0.72
Identities = 29/126 (23%), Positives = 44/126 (34%), Gaps = 2/126 (1%)
Query: 74 TLEDLAETLKKEKLKVKGPALSRKRKKEVDATSPAPST-SSTVKTEGAEATPGAQKRKKS 132
TL++ A T K+ + + K PAP+T T T E P K
Sbjct: 675 TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP 734
Query: 133 TKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPKTVAK-C 191
T K + T P PA ++ + P+ TS P + P T +
Sbjct: 735 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA 794
Query: 192 QVTPRR 197
TP++
Sbjct: 795 PTTPKK 800
Score = 33.1 bits (74), Expect = 0.94
Identities = 78/365 (21%), Positives = 125/365 (34%), Gaps = 56/365 (15%)
Query: 100 KEVDATSPAPSTSSTVKTEGAEATPGAQKRKKSTKEKA-----GP------KGSKVSEEQ 148
KE T+P + +T+K E A TP +K + KE A GP K + + ++
Sbjct: 730 KEPAPTTPKGTAPTTLK-EPAPTTP----KKPAPKELAPTTTKGPTSTTSDKPAPTTPKE 784
Query: 149 TQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPKTVAKCQVTPRRNVLQKRPVIVK 208
T P +P +T + P+P T + PP +S P T T + K P
Sbjct: 785 TAPTTPKEPAPTTP--KKPAPTTPETPPPTTSEVSTPTT------TKEPTTIHKSP---- 832
Query: 209 VLSTTKPFEYETPE-MEKKIMFHATVATQTQFFHVKVLNTSLKEKFNGKKIIIISDYLEY 267
ST + TP+ +E T+T + T+ K+K +
Sbjct: 833 DESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER----------- 881
Query: 268 DSLLEVNEESTVSEAGPNQTFEVPNKIINRAKETLKIDILHKQASGNIVYGVFMLHKKTV 327
L E +T + +T K + + + L T+
Sbjct: 882 -DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTL 940
Query: 328 NQKTTIYEIQDDRGKMDVVGTGQCHNIPCEEG---DKLQLFCFRLRKKNQMSKLISEMHS 384
K T + + T + N P E D+ K + +K + S
Sbjct: 941 APKVTTTK--------KTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTS 992
Query: 385 FIQIKKKTNPRNNDPKSMKLPQEQRQLPYPSEASTTFPESHLRTPQMPPTTPSSSF--FT 442
K KT PR PK+ P++ ++ E+ L+T P TP+S
Sbjct: 993 --TKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVN 1050
Query: 443 KKSED 447
KSED
Sbjct: 1051 PKSED 1055
Score = 32.3 bits (72), Expect = 1.6
Identities = 52/225 (23%), Positives = 72/225 (32%), Gaps = 26/225 (11%)
Query: 392 TNPRNNDPKSMK-----LPQEQRQLPYPSEASTTFPESHLRTPQMPPTTPSSSFFTKKSE 446
T P+ P + K P+E A TT E TP+ P + TK
Sbjct: 711 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPT 770
Query: 447 DTIS-KMNDFMRMQILKEGSHFPGPFMTSIGPAESHPHTPQMPPSTPSSSFLTTLK---- 501
T S K + P P T PA + P TP PP+T S TT K
Sbjct: 771 STTSDKPAPTTPKETAPTTPKEPAP-TTPKKPAPTTPETP--PPTTSEVSTPTTTKEPTT 827
Query: 502 ---------PRLKTEPEEVSIEDSAQS----DLKEVMVLNATESFVYEPKEQKKMFHATV 548
P L EP ++E+S + K + + K ++ T
Sbjct: 828 IHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTP 887
Query: 549 ATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTL 593
T ++ EK T KI A V + PF +
Sbjct: 888 ETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKI 932
Score = 32.0 bits (71), Expect = 2.1
Identities = 39/150 (26%), Positives = 57/150 (38%), Gaps = 17/150 (11%)
Query: 392 TNPRNNDPKSMKLPQEQRQLPYPSEASTTFPESHLRTPQMPPTTPSSSFFTKKSEDTISK 451
T P+ P + P+E A TT E TP+ P + TK+ T
Sbjct: 650 TTPKEPAPTT---PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD 706
Query: 452 MNDFMRMQILKEGSHFP-GPFMTSIGPAESHPHTPQMP-PSTPSSSFLTTLKPRLKTEPE 509
K P G T+ P E P TP+ P P+TP + TTLK T P+
Sbjct: 707 ----------KPAPTTPKGTAPTT--PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK 754
Query: 510 EVSIEDSAQSDLKEVMVLNATESFVYEPKE 539
+ + ++ A + K + + PKE
Sbjct: 755 KPAPKELAPTTTKGPTSTTSDKPAPTTPKE 784
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 42.0 bits (97), Expect = 0.002
Identities = 34/134 (25%), Positives = 55/134 (41%), Gaps = 20/134 (14%)
Query: 73 PTLEDLAETLKKEKLKVKGPALSRKRK------KEVDATSPAPSTSSTVK---------- 116
PT + LA+ K + KGPAL+ ++ KE +T+P T +T+K
Sbjct: 323 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 382
Query: 117 ---TEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSL 173
T+ A TP + +TKE A + + T+ P+P + + P+P T
Sbjct: 383 PTTTKSAPTTP-KEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 441
Query: 174 SAPPNSSSTENPKT 187
P + P T
Sbjct: 442 KPAPTTPKEPAPTT 455
Score = 38.5 bits (88), Expect = 0.022
Identities = 97/428 (22%), Positives = 150/428 (35%), Gaps = 59/428 (13%)
Query: 106 SPAPS-TSSTVK--TEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTA 162
+P PS S T+K T+ + P +K KK + + + VSE Q S + + S+
Sbjct: 119 APPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSST 178
Query: 163 MGRSPSPKTSLS---APPNSSSTENPKTVAKCQVTPRRNVLQKRPVIVKVLSTTKPFEYE 219
+ + S K S + +N K K + TP K PV+ + S +++
Sbjct: 179 IRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTP------KPPVVDEAGSGLDNGDFK 232
Query: 220 TPEMEKKIMFHATVATQTQFFHVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEESTV 279
+ H V+T + K +N N S + ++ +E E +T
Sbjct: 233 VTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTT 292
Query: 280 SEAGPNQTFEVPNKIINRAKETLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIYEIQDD 339
++ QT + AKET I+ K ++ ++ +L K T +TT
Sbjct: 293 NK----QTSTDGKEKTTSAKETQSIE---KTSAKDLAPTSKVLAKPTPKAETTT------ 339
Query: 340 RGKMDVVGTGQCHNIPCEEGDKLQLFCFRLRKKNQMSKLISEMHSFIQIKKKTNPRNNDP 399
G P E K S E T P+ P
Sbjct: 340 --------KGPALTTPKEPTPTTP--------KEPASTTPKEPTPTTIKSAPTTPKEPAP 383
Query: 400 KSMKLPQEQRQLPYPSEASTTFPESHLRTPQMP-PTTPSSSFFTKKSEDTISKMNDFMRM 458
+ K + P P TT E TP+ P PTT TK+ T +K
Sbjct: 384 TTTKSAPTTPKEPAP----TTTKEPAPTTPKEPAPTT------TKEPAPTTTKSAPTTPK 433
Query: 459 QILKEGSHFPGPFMTSIGPAESHPHTPQMP-PSTPSSSFLTTLKPRLKT--EPEEVSIED 515
+ P P P E P TP+ P P+TP TT +P T EP + +
Sbjct: 434 EPAPTTPKKPAPTT----PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKK 489
Query: 516 SAQSDLKE 523
A + KE
Sbjct: 490 PAPTTPKE 497
Score = 37.7 bits (86), Expect = 0.038
Identities = 35/146 (23%), Positives = 50/146 (34%), Gaps = 11/146 (7%)
Query: 70 EDIPTLEDLAETLKKEKLKVKGPALSRKRKKEVDATSPAPSTSSTVKTEGAEATPGAQKR 129
E PT ++ A T KE + KE T+P +T K E +P K
Sbjct: 466 EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTK----EPSPTTPKE 521
Query: 130 KKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPKTVA 189
T K+ P T+ P+P + + PSP T+ P + P T
Sbjct: 522 PAPTTTKSAPT-------TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK 574
Query: 190 KCQVTPRRNVLQKRPVIVKVLSTTKP 215
K T + P +T KP
Sbjct: 575 KPAPTTPKEPAPTTPKEPAPTTTKKP 600
Score = 36.2 bits (82), Expect = 0.11
Identities = 38/151 (25%), Positives = 56/151 (37%), Gaps = 12/151 (7%)
Query: 70 EDIPTLEDLAETLKKEKLKV--KGPALSRKRKKEVDATS-PAPSTSSTVKTEGAEATPGA 126
E PT A T KE K PA + ++ T PAP+T+ + T E P
Sbjct: 380 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 439
Query: 127 QKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPK 186
K+ T K + + + ++ P +P +T +PK P + PK
Sbjct: 440 PKKPAPTTPK---EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK 496
Query: 187 TVAKCQVTPRRNVLQKRPVIVKVLSTTKPFE 217
A TP+ + P K S T P E
Sbjct: 497 EPA--PTTPK----EPAPTTTKEPSPTTPKE 521
Score = 35.8 bits (81), Expect = 0.14
Identities = 34/141 (24%), Positives = 50/141 (35%), Gaps = 10/141 (7%)
Query: 73 PTLEDLAETLKKEKLKVKGPALSRKRKKEVDATSPAPSTSSTVKTEGAEATPGAQKRKKS 132
P+L ++T K+ L V + KE T+ ST KT A+ T +K
Sbjct: 262 PSLPPNSDTSKETSLTVNKE--TTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK---- 315
Query: 133 TKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPKTVAKCQ 192
T K SKV + T G + + P+P T + P T+
Sbjct: 316 TSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP 375
Query: 193 VTPRRNVLQKRPVIVKVLSTT 213
TP+ + P K TT
Sbjct: 376 TTPK----EPAPTTTKSAPTT 392
Score = 34.7 bits (78), Expect = 0.32
Identities = 35/127 (27%), Positives = 48/127 (37%), Gaps = 21/127 (16%)
Query: 392 TNPRNNDPKSMKLPQEQRQLPYPS---EASTTFPESHL-RTPQMP-PTTPSSSFFTKKSE 446
T P+ P + K P + P P+ E + T P+ TP+ P PTTP T E
Sbjct: 454 TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKE 513
Query: 447 DTISKMNDFMRMQILKEGSHFPGPFMTSIGPA---ESHPHTPQMPPSTPSSSFLTTLKPR 503
+ + + P P T P E P T + P+TP TT K
Sbjct: 514 PSPTTPKE-------------PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP 560
Query: 504 LKTEPEE 510
T P+E
Sbjct: 561 APTTPKE 567
Score = 33.9 bits (76), Expect = 0.55
Identities = 35/136 (25%), Positives = 53/136 (38%), Gaps = 19/136 (13%)
Query: 390 KKTNPRNNDPKSMKLPQEQRQLPYPSEASTTFPESHLRTPQMP-PTTPSSSFFTKKSEDT 448
KK P + + P++ A TT E TP+ P PTTP ++ E
Sbjct: 622 KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA 681
Query: 449 ISKMNDFMRMQILKEGSHFPGPFMTSIGPAESHPHTP-QMPPSTPSSSFLTTLKPRLKTE 507
+ + P P P E P TP + P+TP + TTLK T
Sbjct: 682 PTTPKE-------------PAPTT----PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTT 724
Query: 508 PEEVSIEDSAQSDLKE 523
P++ + ++ A + KE
Sbjct: 725 PKKPAPKELAPTTTKE 740
Score = 33.5 bits (75), Expect = 0.72
Identities = 29/126 (23%), Positives = 44/126 (34%), Gaps = 2/126 (1%)
Query: 74 TLEDLAETLKKEKLKVKGPALSRKRKKEVDATSPAPST-SSTVKTEGAEATPGAQKRKKS 132
TL++ A T K+ + + K PAP+T T T E P K
Sbjct: 716 TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP 775
Query: 133 TKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPKTVAK-C 191
T K + T P PA ++ + P+ TS P + P T +
Sbjct: 776 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA 835
Query: 192 QVTPRR 197
TP++
Sbjct: 836 PTTPKK 841
Score = 33.1 bits (74), Expect = 0.94
Identities = 78/365 (21%), Positives = 125/365 (34%), Gaps = 56/365 (15%)
Query: 100 KEVDATSPAPSTSSTVKTEGAEATPGAQKRKKSTKEKA-----GP------KGSKVSEEQ 148
KE T+P + +T+K E A TP +K + KE A GP K + + ++
Sbjct: 771 KEPAPTTPKGTAPTTLK-EPAPTTP----KKPAPKELAPTTTKGPTSTTSDKPAPTTPKE 825
Query: 149 TQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPKTVAKCQVTPRRNVLQKRPVIVK 208
T P +P +T + P+P T + PP +S P T T + K P
Sbjct: 826 TAPTTPKEPAPTTP--KKPAPTTPETPPPTTSEVSTPTT------TKEPTTIHKSP---- 873
Query: 209 VLSTTKPFEYETPE-MEKKIMFHATVATQTQFFHVKVLNTSLKEKFNGKKIIIISDYLEY 267
ST + TP+ +E T+T + T+ K+K +
Sbjct: 874 DESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER----------- 922
Query: 268 DSLLEVNEESTVSEAGPNQTFEVPNKIINRAKETLKIDILHKQASGNIVYGVFMLHKKTV 327
L E +T + +T K + + + L T+
Sbjct: 923 -DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTL 981
Query: 328 NQKTTIYEIQDDRGKMDVVGTGQCHNIPCEEG---DKLQLFCFRLRKKNQMSKLISEMHS 384
K T + + T + N P E D+ K + +K + S
Sbjct: 982 APKVTTTK--------KTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTS 1033
Query: 385 FIQIKKKTNPRNNDPKSMKLPQEQRQLPYPSEASTTFPESHLRTPQMPPTTPSSSF--FT 442
K KT PR PK+ P++ ++ E+ L+T P TP+S
Sbjct: 1034 --TKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVN 1091
Query: 443 KKSED 447
KSED
Sbjct: 1092 PKSED 1096
Score = 32.3 bits (72), Expect = 1.6
Identities = 52/225 (23%), Positives = 72/225 (32%), Gaps = 26/225 (11%)
Query: 392 TNPRNNDPKSMK-----LPQEQRQLPYPSEASTTFPESHLRTPQMPPTTPSSSFFTKKSE 446
T P+ P + K P+E A TT E TP+ P + TK
Sbjct: 752 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPT 811
Query: 447 DTIS-KMNDFMRMQILKEGSHFPGPFMTSIGPAESHPHTPQMPPSTPSSSFLTTLK---- 501
T S K + P P T PA + P TP PP+T S TT K
Sbjct: 812 STTSDKPAPTTPKETAPTTPKEPAP-TTPKKPAPTTPETP--PPTTSEVSTPTTTKEPTT 868
Query: 502 ---------PRLKTEPEEVSIEDSAQS----DLKEVMVLNATESFVYEPKEQKKMFHATV 548
P L EP ++E+S + K + + K ++ T
Sbjct: 869 IHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTP 928
Query: 549 ATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTL 593
T ++ EK T KI A V + PF +
Sbjct: 929 ETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKI 973
Score = 32.0 bits (71), Expect = 2.1
Identities = 39/150 (26%), Positives = 57/150 (38%), Gaps = 17/150 (11%)
Query: 392 TNPRNNDPKSMKLPQEQRQLPYPSEASTTFPESHLRTPQMPPTTPSSSFFTKKSEDTISK 451
T P+ P + P+E A TT E TP+ P + TK+ T
Sbjct: 691 TTPKEPAPTT---PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD 747
Query: 452 MNDFMRMQILKEGSHFP-GPFMTSIGPAESHPHTPQMP-PSTPSSSFLTTLKPRLKTEPE 509
K P G T+ P E P TP+ P P+TP + TTLK T P+
Sbjct: 748 ----------KPAPTTPKGTAPTT--PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK 795
Query: 510 EVSIEDSAQSDLKEVMVLNATESFVYEPKE 539
+ + ++ A + K + + PKE
Sbjct: 796 KPAPKELAPTTTKGPTSTTSDKPAPTTPKE 825
>gi|56118310 nuclear casein kinase and cyclin-dependent kinase
substrate 1 [Homo sapiens]
Length = 243
Score = 42.0 bits (97), Expect = 0.002
Identities = 37/113 (32%), Positives = 43/113 (38%), Gaps = 19/113 (16%)
Query: 77 DLAETLKKEKLKVKGPALSRKRKKEVDATSPAPSTSSTVKTEGAEATPGAQKRKKSTKEK 136
D + KK K VK RK KK A T S VK +G P A K K ++
Sbjct: 145 DYGSSKKKNKKMVKKSKPERKEKKMPKPRLKATVTPSPVKGKGKVGRPTASKASK--EKT 202
Query: 137 AGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPKTVA 189
PK EE +P SP P KTS S PP S E + A
Sbjct: 203 PSPK-----EEDEEPESP------------PEKKTSTSPPPEKSGDEGSEDEA 238
>gi|155722994 zinc finger CCCH-type containing 3 [Homo sapiens]
Length = 948
Score = 42.0 bits (97), Expect = 0.002
Identities = 31/123 (25%), Positives = 47/123 (38%), Gaps = 2/123 (1%)
Query: 95 SRKRKKEVDATSPAPSTSSTVKTEGAEATPGAQKRKKSTK--EKAGPKGSKVSEEQTQPP 152
++KR ATSPAP S A+ G +K S + + + + PP
Sbjct: 799 TQKRHSRRAATSPAPGPSDATARSRVSASHGPRKPSASQRPTRQTPSSAALTAAAVAAPP 858
Query: 153 SPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPKTVAKCQVTPRRNVLQKRPVIVKVLST 212
G S + ++ S +S S+PP S E P N L K P + + S+
Sbjct: 859 HCPGGSASPSSSKASSSSSSSSSPPASLDHEAPSLQEAALAAACSNRLCKLPSFISLQSS 918
Query: 213 TKP 215
P
Sbjct: 919 PSP 921
>gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens]
Length = 1217
Score = 41.2 bits (95), Expect = 0.003
Identities = 27/94 (28%), Positives = 41/94 (43%), Gaps = 2/94 (2%)
Query: 106 SPAPSTSSTVKTEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGR 165
S +P+TSS + + A ++ A +K K+ P+GS +S E + SPA S A
Sbjct: 41 SGSPATSSALSAQAAPSSSFAAALRKLAKQAEEPRGSSLSSESSPVSSPATNHSSPASTP 100
Query: 166 SPSPKTSLSAPPNSSSTENPKTVAKCQVTPRRNV 199
P + PP S P T + P + V
Sbjct: 101 KRVPMGPIIVPPGGHSV--PSTPPVVTIAPTKTV 132
>gi|118421089 chromodomain helicase DNA binding protein 2 isoform 1
[Homo sapiens]
Length = 1828
Score = 40.8 bits (94), Expect = 0.005
Identities = 33/106 (31%), Positives = 49/106 (46%), Gaps = 18/106 (16%)
Query: 82 LKKEKLKVKGPALSRKRKKE--VDATSPA----PSTSSTVKTEGAEATPGAQKRKK---- 131
LKK K +VK + K+E ++ +SP PS VK +G E +P +K+KK
Sbjct: 1339 LKKRKPRVKKENKVPRLKEEHGIELSSPRHSDNPSEEGEVKDDGLEKSPMKKKQKKKENK 1398
Query: 132 --------STKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSP 169
S K+K G K K S+++ + P A S+ RS P
Sbjct: 1399 ENKEKQMSSRKDKEGDKERKKSKDKKEKPKSGDAKSSSKSKRSQGP 1444
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 40.0 bits (92), Expect = 0.008
Identities = 32/123 (26%), Positives = 51/123 (41%), Gaps = 12/123 (9%)
Query: 116 KTEGAEATPGAQKRKKSTKEKAG----PKGSK-------VSEEQTQPPSPAGAGMSTAMG 164
+ + A+A P K S + + PK K V + PP PA A A G
Sbjct: 153 QAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANG 212
Query: 165 RSPSPKTSLSAPPNSSSTENPKTVAKCQVT-PRRNVLQKRPVIVKVLSTTKPFEYETPEM 223
++ S +S S+ +S +E K A + T P++ V+ K PV T K E
Sbjct: 213 KAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSS 272
Query: 224 EKK 226
+++
Sbjct: 273 DEE 275
Score = 34.7 bits (78), Expect = 0.32
Identities = 28/126 (22%), Positives = 53/126 (42%), Gaps = 15/126 (11%)
Query: 84 KEKLKVKGPALSRKRKKEVDATSPAPSTSSTVKTEGAEATPGAQKRK-----------KS 132
+ KL+ GP +++K KK+ ++ S+ + +G A A K K+
Sbjct: 65 ERKLQANGP-VAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKA 123
Query: 133 TKEKAGPKGSKVSEEQTQPPSPAGAGM---STAMGRSPSPKTSLSAPPNSSSTENPKTVA 189
++ + + S +E+ Q P G+ + A P S + +SSS + P
Sbjct: 124 SESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQ 183
Query: 190 KCQVTP 195
K ++TP
Sbjct: 184 KPKITP 189
>gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo
sapiens]
Length = 929
Score = 39.3 bits (90), Expect = 0.013
Identities = 26/121 (21%), Positives = 46/121 (38%), Gaps = 3/121 (2%)
Query: 92 PALSRKRKKEVDATSPAPSTSSTVKTEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQP 151
P L+ K ++ P + S T KT+ ++PG + + T + GS + +T
Sbjct: 247 PMLAPVAKSQMPTAKPLETKSFTPKTKTKTSSPGQKTKSPKTAQSPAMVGSPIRSPKTVS 306
Query: 152 PSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPKTVAKCQVTPRRNVLQKRPVIVKVLS 211
G S + SPK + P E P ++ + + K + VK +
Sbjct: 307 KEKKSPGRSKSPKSPKSPKVTTHIPQTPVRPETPNRTPSATLSEK---ISKETIQVKQIQ 363
Query: 212 T 212
T
Sbjct: 364 T 364
Score = 31.2 bits (69), Expect = 3.6
Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 11/61 (18%)
Query: 389 KKKTNPRNNDPKSMKLPQEQRQLPYPSEASTTFPESHLRTPQMPPTTPSSSFFTKKSEDT 448
+KK+ R+ PKS K P+ +T P++ +R P+ P TPS++ K S++T
Sbjct: 308 EKKSPGRSKSPKSPKSPK----------VTTHIPQTPVR-PETPNRTPSATLSEKISKET 356
Query: 449 I 449
I
Sbjct: 357 I 357
>gi|33667044 ABI gene family, member 3 (NESH) binding protein [Homo
sapiens]
Length = 1075
Score = 39.3 bits (90), Expect = 0.013
Identities = 55/215 (25%), Positives = 76/215 (35%), Gaps = 32/215 (14%)
Query: 29 LSNDLKLNLKMREEYDKIQIADLMEEKFRGDAGLGKLIKIFEDIP-----TLEDLAETLK 83
+S D K+ YD +E D+ +I + IP TLE TL
Sbjct: 375 ISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLA 434
Query: 84 KEKLKVKGPALSRKRKKEVDATSPAPS-TSSTVKTEGAEATPGAQKRKKSTKEKAG---P 139
+ L E+ T+PAP T+S T P + K AG P
Sbjct: 435 PSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITP 494
Query: 140 KGSKVSEEQTQPPSPAGAGMSTAMGR----------SPSPKTSLSAPPNSSSTENPKTVA 189
K SK E P+P + + P+PK + APP PKT
Sbjct: 495 KISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPP------KPKT-- 546
Query: 190 KCQVTPRRNVLQKRPV-IVKVLSTTKPFEYETPEM 223
+PR + Q +PV V T KP +PE+
Sbjct: 547 ----SPRPRIPQTQPVPKVPQRVTAKPKTSPSPEV 577
>gi|157694494 MYB binding protein 1a isoform 1 [Homo sapiens]
Length = 1332
Score = 39.3 bits (90), Expect = 0.013
Identities = 32/122 (26%), Positives = 51/122 (41%), Gaps = 10/122 (8%)
Query: 87 LKVKGPALSRKRKKEVDATSPAPSTSSTVKTEGAEATPGAQKRKKSTKEKAGPKGSKVSE 146
L V+ P L +K KE+ + + +P + K + P +KRKK E P +E
Sbjct: 1142 LGVQRPKLEKKDAKEIPSATQSPISK---KRKKKGFLPETKKRKKRKSEDGTP-----AE 1193
Query: 147 EQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPKTVAKCQVTPRRNVLQKRPVI 206
+ T P+ G +MGR +T P ++ T K+ A T + K P +
Sbjct: 1194 DGT--PAATGGSQPPSMGRKKRNRTKAKVPAQANGTPTTKSPAPGAPTRSPSTPAKSPKL 1251
Query: 207 VK 208
K
Sbjct: 1252 QK 1253
Score = 31.2 bits (69), Expect = 3.6
Identities = 28/121 (23%), Positives = 47/121 (38%), Gaps = 11/121 (9%)
Query: 83 KKEKLKVKGPALSRKRKKEVDATSPAPSTSSTVKTEGAEATPGAQKRKKSTKEKAGPKGS 142
KK K K P +++K++ + +PA + T G++ P + RKK + KA
Sbjct: 1167 KKRKKKGFLPETKKRKKRKSEDGTPA-EDGTPAATGGSQ--PPSMGRKKRNRTKAKVPAQ 1223
Query: 143 KVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPKTVAKCQVTPRRNVLQK 202
T+ P+P + SP T +P + P V +P QK
Sbjct: 1224 ANGTPTTKSPAPGAP--------TRSPSTPAKSPKLQKKNQKPSQVNGAPGSPTEPAGQK 1275
Query: 203 R 203
+
Sbjct: 1276 Q 1276
>gi|157694492 MYB binding protein 1a isoform 2 [Homo sapiens]
Length = 1328
Score = 39.3 bits (90), Expect = 0.013
Identities = 32/122 (26%), Positives = 51/122 (41%), Gaps = 10/122 (8%)
Query: 87 LKVKGPALSRKRKKEVDATSPAPSTSSTVKTEGAEATPGAQKRKKSTKEKAGPKGSKVSE 146
L V+ P L +K KE+ + + +P + K + P +KRKK E P +E
Sbjct: 1142 LGVQRPKLEKKDAKEIPSATQSPISK---KRKKKGFLPETKKRKKRKSEDGTP-----AE 1193
Query: 147 EQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPKTVAKCQVTPRRNVLQKRPVI 206
+ T P+ G +MGR +T P ++ T K+ A T + K P +
Sbjct: 1194 DGT--PAATGGSQPPSMGRKKRNRTKAKVPAQANGTPTTKSPAPGAPTRSPSTPAKSPKL 1251
Query: 207 VK 208
K
Sbjct: 1252 QK 1253
Score = 31.2 bits (69), Expect = 3.6
Identities = 28/121 (23%), Positives = 47/121 (38%), Gaps = 11/121 (9%)
Query: 83 KKEKLKVKGPALSRKRKKEVDATSPAPSTSSTVKTEGAEATPGAQKRKKSTKEKAGPKGS 142
KK K K P +++K++ + +PA + T G++ P + RKK + KA
Sbjct: 1167 KKRKKKGFLPETKKRKKRKSEDGTPA-EDGTPAATGGSQ--PPSMGRKKRNRTKAKVPAQ 1223
Query: 143 KVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPKTVAKCQVTPRRNVLQK 202
T+ P+P + SP T +P + P V +P QK
Sbjct: 1224 ANGTPTTKSPAPGAP--------TRSPSTPAKSPKLQKKNQKPSQVNGAPGSPTEPAGQK 1275
Query: 203 R 203
+
Sbjct: 1276 Q 1276
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 39.3 bits (90), Expect = 0.013
Identities = 40/161 (24%), Positives = 61/161 (37%), Gaps = 21/161 (13%)
Query: 70 EDIPTLEDLAETLKKE----KLKVKGPALSRKRKKEVDATSPAPSTSSTVKTEGAEATPG 125
++IP E++ +K+E ++KVK P KK + +PA + K E P
Sbjct: 812 KEIPKKEEVKSPVKEEEKPQEVKVKEPP-----KKAEEEKAPATPKTEEKKDSKKEEAPK 866
Query: 126 AQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENP 185
+ K +EK P K E + + A A + P AP E+
Sbjct: 867 KEAPKPKVEEKKEPAVEKPKESKVE------AKKEEAEDKKKVPTPEKEAPAKVEVKEDA 920
Query: 186 KTVAKCQVTPRRNVLQKRPVIVKVLSTTKPFEYETPEMEKK 226
K K +V +K P K +KP E + EKK
Sbjct: 921 KPKEKTEVA------KKEPDDAKAKEPSKPAEKKEAAPEKK 955
Score = 34.3 bits (77), Expect = 0.42
Identities = 38/144 (26%), Positives = 52/144 (36%), Gaps = 20/144 (13%)
Query: 73 PTLEDLAETLKKEKLKVKGPALSRKRKKEVDATSPAPSTSSTVKTEGAEATPGAQKRKKS 132
P E+ ++ K+E K + P + KKE P S K E + K+K
Sbjct: 851 PKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAED------KKKVP 904
Query: 133 TKEKAGPKGSKVSEE--QTQPPSPAGAGMSTAMGRSPS-PKTSLSAPPNSSST------- 182
T EK P +V E+ + A A + PS P A P T
Sbjct: 905 TPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKK 964
Query: 183 --ENPKTVAKCQVTPRRNVLQKRP 204
E PKT AK + + L K P
Sbjct: 965 PEEKPKTEAKAKEDDK--TLSKEP 986
Score = 33.1 bits (74), Expect = 0.94
Identities = 44/157 (28%), Positives = 64/157 (40%), Gaps = 25/157 (15%)
Query: 73 PTLEDLAETLKKEKLKVK----GPALSRKRKKEVDATSPAPSTSSTVKTEGAEATPGAQK 128
P E+ A K+ K VK PA ++ +KE +A SPA S +K
Sbjct: 504 PPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKE-EAKSPAEVKS-------------PEK 549
Query: 129 RKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPKTV 188
K KE+A S E+ + SPA S +SP+ K +P + S E K+
Sbjct: 550 AKSPAKEEAKSPPEAKSPEKEEAKSPAEV-KSPEKAKSPA-KEEAKSPAEAKSPEKAKSP 607
Query: 189 AKCQVTPRRNVLQKRPVIVKVLSTTKPFEYETPEMEK 225
K + + K PV + S P E ++PE K
Sbjct: 608 VKEEA--KSPAEAKSPVKEEAKS---PAEVKSPEKAK 639
Score = 31.6 bits (70), Expect = 2.7
Identities = 35/153 (22%), Positives = 54/153 (35%), Gaps = 19/153 (12%)
Query: 79 AETLKKEKLKVKGPALSRKRKKEVDATSPAPSTSSTVKTEGAEA----TPGAQKRKKSTK 134
A+T KE+ + K K V +P + + E A+A P ++ K K
Sbjct: 766 AKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVK 825
Query: 135 EKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPKTVAKCQVT 194
E+ P+ KV E PP A + A ++ K S PK K
Sbjct: 826 EEEKPQEVKVKE----PPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEK---- 877
Query: 195 PRRNVLQKRPVIVKVLSTTKPFEYETPEMEKKI 227
K P + K + + E E +KK+
Sbjct: 878 -------KEPAVEKPKESKVEAKKEEAEDKKKV 903
>gi|194363768 homeobox D9 [Homo sapiens]
Length = 352
Score = 38.9 bits (89), Expect = 0.017
Identities = 44/181 (24%), Positives = 74/181 (40%), Gaps = 23/181 (12%)
Query: 91 GPALSRKRK-KEVDATSPAPSTSSTVKTEGAEATPGAQKRKKST--KEKAGPKGSKVS-- 145
GPA R K +PAP+T+++ + + + + KR + + +E G G + S
Sbjct: 151 GPANGRHYGIKPETRAAPAPATAASTTSSSSTSLSSSSKRTECSVARESQGSSGPEFSCN 210
Query: 146 -------EEQTQPPSP-AGAGMSTAMGRSPSPKTSLSAP-PNSSSTENPKTVAKCQV--- 193
T P AG G +T G S P P P S E K ++ Q
Sbjct: 211 SFLQEKAAAATGGTGPGAGIGAATGTGGSSEPSACSDHPIPGCSLKEEEKQHSQPQQQQL 270
Query: 194 ---TPRRNVLQKRPVIVKVLSTTKPFEYETPEMEKKIMFHATVATQTQFFHVKVLNTSLK 250
P N + R K TK Y+T E+EK+ +F+ + ++ ++LN + +
Sbjct: 271 DPNNPAANWIHARSTRKKRCPYTK---YQTLELEKEFLFNMYLTRDRRYEVARILNLTER 327
Query: 251 E 251
+
Sbjct: 328 Q 328
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 38.5 bits (88), Expect = 0.022
Identities = 29/106 (27%), Positives = 44/106 (41%), Gaps = 6/106 (5%)
Query: 97 KRKKEVDATSPAPSTSSTVKTE-----GAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQP 151
KR++ + SP P+TSS+ + G G K+KK G K S E+
Sbjct: 605 KRRRRRRSASPPPATSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPA 664
Query: 152 PSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPKTVAKCQVTPRR 197
P+P +G ST+ G S + P T++ K +T R
Sbjct: 665 PAPPPSG-STSCGDRDSRRRGAVPPSIQDLTDHDLFAIKRTITVGR 709
Score = 37.4 bits (85), Expect = 0.050
Identities = 37/123 (30%), Positives = 56/123 (45%), Gaps = 16/123 (13%)
Query: 83 KKEKLKVKGPALSRKRKKEVDATSPAPSTSSTVKTEGAEATPGAQKRKKSTK-----EKA 137
K +K KVK A ++K K T P+ T V++ G G Q K +K + A
Sbjct: 896 KPKKTKVKAKAGAKKTKGTKGKTKPS-KTRKKVRSGGGSGGSGGQVSLKKSKADSCSQAA 954
Query: 138 GPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPKTVAKCQVTPRR 197
G KG+ E+T S +G + + +P PK +APP + T + +TV TP
Sbjct: 955 GTKGA----EET---SWSGEERAAKVPSTPPPK---AAPPPPALTPDSQTVDSSCKTPEV 1004
Query: 198 NVL 200
+ L
Sbjct: 1005 SFL 1007
Score = 36.2 bits (82), Expect = 0.11
Identities = 36/141 (25%), Positives = 59/141 (41%), Gaps = 15/141 (10%)
Query: 97 KRKKEVDATSPAPSTSSTVKTEGAEATPGAQKRKKS-TKEKAGPKGSKVSEEQTQPP--- 152
K ++ ++ SP TE A+A PG+ K KK+ K KAG K +K ++ +T+P
Sbjct: 865 KFSRDRESRSPFLKPDERAPTEMAKAAPGSTKPKKTKVKAKAGAKKTKGTKGKTKPSKTR 924
Query: 153 -------SPAGAGMSTAMGRSPSPKTSLSA---PPNSSSTENPKTVAKCQVTPRRNVLQK 202
G+G ++ +S + S +A +S + AK TP
Sbjct: 925 KKVRSGGGSGGSGGQVSLKKSKADSCSQAAGTKGAEETSWSGEERAAKVPSTPPPKAAPP 984
Query: 203 RPVIVKVLSTTKPFEYETPEM 223
P + S T +TPE+
Sbjct: 985 PPALTPD-SQTVDSSCKTPEV 1004
Score = 32.0 bits (71), Expect = 2.1
Identities = 25/106 (23%), Positives = 45/106 (42%), Gaps = 15/106 (14%)
Query: 96 RKRKKEVDATSPAPSTSSTVKTEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPA 155
R+RK+ +A A S+S T A A+P K+ +S K G S + +++ S +
Sbjct: 521 RERKRSGEAKEAASSSSGTQPAPPAPASPWDSKKHRSRDRKPGSHASSSARRRSRSRSRS 580
Query: 156 ---------------GAGMSTAMGRSPSPKTSLSAPPNSSSTENPK 186
G+ S + + + S S PP +SS+ + +
Sbjct: 581 RSTRRRSRSTDRRRGGSRRSRSREKRRRRRRSASPPPATSSSSSSR 626
>gi|209862789 microtubule associated monoxygenase, calponin and LIM
domain containing 3 isoform 1 [Homo sapiens]
Length = 2002
Score = 38.5 bits (88), Expect = 0.022
Identities = 43/171 (25%), Positives = 74/171 (43%), Gaps = 19/171 (11%)
Query: 51 LMEEKFRGDAGLGKLIKIFEDIPTLEDLAETLKKEKLK-----VKGPAL--------SRK 97
L +E R A G L +P + A+ L +E+++ VK AL SR
Sbjct: 1561 LAKENGRLPALEGTLQPQKRGLPLVSAEAKELAEERMRAREKSVKSQALRDAMARQLSRM 1620
Query: 98 RKKEVDATSPAPSTSSTVKTEGAEATPGAQKRKK-STKEKAGPKGSKVSEEQTQPPSPAG 156
++ E+ + +P P +S+ ++G E P + R E+ K SEE PPS +G
Sbjct: 1621 QQMELASGAPRPRKASSAPSQGKERRPDSPTRPTLRGSEEPTLKHEATSEEVLSPPSDSG 1680
Query: 157 ---AGMSTAMGRSPSPK--TSLSAPPNSSSTENPKTVAKCQVTPRRNVLQK 202
+++ G S K +SL +P + + K + P N+L++
Sbjct: 1681 GPDGSFTSSEGSSGKSKKRSSLFSPRRNKKEKKSKGEGRPPEKPSSNLLEE 1731
>gi|117190342 PHD finger protein 2 [Homo sapiens]
Length = 1096
Score = 38.1 bits (87), Expect = 0.029
Identities = 32/120 (26%), Positives = 46/120 (38%), Gaps = 18/120 (15%)
Query: 95 SRKRKKEVDATSPAPSTSSTVKTEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSP 154
S KRK + TSP+ STS + T TP + +T S+ S+E + P P
Sbjct: 954 SAKRKLTPNTTSPSTSTSISAGTTSTSTTPASTTPASTTPASTSTASSQASQEGSSPEPP 1013
Query: 155 ---------------AGAGMSTAMGRSPSPKTS---LSAPPNSSSTENPKTVAKCQVTPR 196
AG GR+ P L+ S+S+ N T AK + T +
Sbjct: 1014 PESHSSSLADHEYTAAGTFTGAQAGRTSQPMAPGVFLTQRRPSASSPNNNTAAKGKRTKK 1073
Score = 32.3 bits (72), Expect = 1.6
Identities = 29/102 (28%), Positives = 37/102 (36%), Gaps = 2/102 (1%)
Query: 95 SRKRKKEVDAT-SPAPSTSSTVKTEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPS 153
S+KRK DA SP +V + G + T A EEQ
Sbjct: 893 SKKRKGSDDAPYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKK 952
Query: 154 PAGAGMSTAMGRSPSPKTSLSAPPNSSSTENPKTVAKCQVTP 195
+ T SPS TS+SA S+ST P + TP
Sbjct: 953 KSAKRKLTPNTTSPSTSTSISAGTTSTST-TPASTTPASTTP 993
Score = 32.3 bits (72), Expect = 1.6
Identities = 20/71 (28%), Positives = 28/71 (39%)
Query: 112 SSTVKTEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKT 171
S K+ + TP ST AG + + T P S A STA ++ +
Sbjct: 949 SKKKKSAKRKLTPNTTSPSTSTSISAGTTSTSTTPASTTPASTTPASTSTASSQASQEGS 1008
Query: 172 SLSAPPNSSST 182
S PP S S+
Sbjct: 1009 SPEPPPESHSS 1019
>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
Length = 1278
Score = 37.7 bits (86), Expect = 0.038
Identities = 33/107 (30%), Positives = 45/107 (42%), Gaps = 10/107 (9%)
Query: 103 DATSPAP---STSSTVKTEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGM 159
D TSP S S +K EG + T K + K K P K + + +P PA G+
Sbjct: 102 DTTSPETPDSSASKVLKREGTDTTAKTSKLR-GLKPKKAPTARKTTTRRPKPTRPASTGV 160
Query: 160 STAMGRSPSPKTSLSAPPNSSSTENPKTVAKCQVTPRRNVLQKRPVI 206
+ G S S S SA S+ P T A+ TP + PV+
Sbjct: 161 A---GASSSLGPSGSASAGELSSSEPSTPAQ---TPLAAPIIPTPVL 201
>gi|50659104 RAB11 family interacting protein 1 isoform 3 [Homo
sapiens]
Length = 1283
Score = 37.7 bits (86), Expect = 0.038
Identities = 37/123 (30%), Positives = 50/123 (40%), Gaps = 14/123 (11%)
Query: 63 GKLIKIFEDIPTLEDLAETLKKEKLKVKGPALSRKRKKEVDATSPAPSTSSTVKTEGAEA 122
G + +FED+ E AE K + + P +S R + A P S EA
Sbjct: 499 GSSLNLFEDVQITEPEAEPESKSEPR---PPISSPRAPQTRAVKPRLEVSP-------EA 548
Query: 123 TPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPKTSLSAP---PNS 179
P A+ + + P S Q PS G G T SPS +SLS+P P S
Sbjct: 549 QPTARLPSPTDSPSSLPPLPS-SSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPIS 607
Query: 180 SST 182
+ST
Sbjct: 608 TST 610
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.363
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,646,004
Number of Sequences: 37866
Number of extensions: 1436034
Number of successful extensions: 9310
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 63
Number of HSP's successfully gapped in prelim test: 417
Number of HSP's that attempted gapping in prelim test: 7697
Number of HSP's gapped (non-prelim): 1904
length of query: 729
length of database: 18,247,518
effective HSP length: 110
effective length of query: 619
effective length of database: 14,082,258
effective search space: 8716917702
effective search space used: 8716917702
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.