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Search of human proteins with 103471995
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|103471995 serum response factor binding protein 1 [Homo
sapiens]
(429 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|103471995 serum response factor binding protein 1 [Homo sapiens] 837 0.0
gi|87299628 biorientation of chromosomes in cell division 1-like... 49 1e-05
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 47 3e-05
gi|38044112 restin isoform b [Homo sapiens] 44 2e-04
gi|4506751 restin isoform a [Homo sapiens] 44 2e-04
gi|21396500 HIRA interacting protein 3 [Homo sapiens] 44 3e-04
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 42 8e-04
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 42 0.001
gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens] 42 0.001
gi|32484979 adaptor-related protein complex 3, beta 1 subunit [H... 41 0.002
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 41 0.002
gi|217330641 IWS1 homolog [Homo sapiens] 41 0.002
gi|4507241 structure specific recognition protein 1 [Homo sapiens] 41 0.002
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 41 0.002
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 41 0.002
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 40 0.003
gi|117938307 doublecortin domain containing 2 [Homo sapiens] 40 0.003
gi|221219020 NYD-SP11 protein [Homo sapiens] 40 0.004
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 40 0.004
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 40 0.004
gi|71061468 centromere protein E [Homo sapiens] 40 0.004
gi|47578107 delangin isoform B [Homo sapiens] 40 0.004
gi|47578105 delangin isoform A [Homo sapiens] 40 0.004
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] 40 0.005
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens] 40 0.005
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr... 39 0.007
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr... 39 0.007
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 39 0.007
gi|38788333 remodeling and spacing factor 1 [Homo sapiens] 39 0.009
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 39 0.009
>gi|103471995 serum response factor binding protein 1 [Homo sapiens]
Length = 429
Score = 837 bits (2163), Expect = 0.0
Identities = 429/429 (100%), Positives = 429/429 (100%)
Query: 1 MAQPGTLNLNNEVVKMRKEVKRIRVLVIRKLVRSVGRLKSKKGTEDALLKNQRRAQRLLE 60
MAQPGTLNLNNEVVKMRKEVKRIRVLVIRKLVRSVGRLKSKKGTEDALLKNQRRAQRLLE
Sbjct: 1 MAQPGTLNLNNEVVKMRKEVKRIRVLVIRKLVRSVGRLKSKKGTEDALLKNQRRAQRLLE 60
Query: 61 EIHAMKELKPDIVTKSALGDDINFEKIFKKPDSTATERAIARLAVHPLLKKKIDVLKAAV 120
EIHAMKELKPDIVTKSALGDDINFEKIFKKPDSTATERAIARLAVHPLLKKKIDVLKAAV
Sbjct: 61 EIHAMKELKPDIVTKSALGDDINFEKIFKKPDSTATERAIARLAVHPLLKKKIDVLKAAV 120
Query: 121 QAFKEARQNVAEVESSKNASEDNHSENTLYSNDNGSNLQREATVISEQKVKETKILAKKP 180
QAFKEARQNVAEVESSKNASEDNHSENTLYSNDNGSNLQREATVISEQKVKETKILAKKP
Sbjct: 121 QAFKEARQNVAEVESSKNASEDNHSENTLYSNDNGSNLQREATVISEQKVKETKILAKKP 180
Query: 181 IHNSKEKIAKMEHGPKAVTIANSPSKPSEKDSVVSLESQKTPADPKLKTLSQTKKNKGSD 240
IHNSKEKIAKMEHGPKAVTIANSPSKPSEKDSVVSLESQKTPADPKLKTLSQTKKNKGSD
Sbjct: 181 IHNSKEKIAKMEHGPKAVTIANSPSKPSEKDSVVSLESQKTPADPKLKTLSQTKKNKGSD 240
Query: 241 SSLSGNSDGGEEFCEEEKEYFDDSTEERFYKQSSMSEDSDSGDDFFIGKVRRTRKKESSC 300
SSLSGNSDGGEEFCEEEKEYFDDSTEERFYKQSSMSEDSDSGDDFFIGKVRRTRKKESSC
Sbjct: 241 SSLSGNSDGGEEFCEEEKEYFDDSTEERFYKQSSMSEDSDSGDDFFIGKVRRTRKKESSC 300
Query: 301 HSSVKEQKPLEKVFLKEDTGETHGDTRNDKIKPSTETRKLESVFFHSLSGSKSSRRNFKE 360
HSSVKEQKPLEKVFLKEDTGETHGDTRNDKIKPSTETRKLESVFFHSLSGSKSSRRNFKE
Sbjct: 301 HSSVKEQKPLEKVFLKEDTGETHGDTRNDKIKPSTETRKLESVFFHSLSGSKSSRRNFKE 360
Query: 361 QAPKTRSLDFPQNEPQIKNQFNKKLSGRLENTKQQLQLPLHPSWEASRRRKEQQSNIAVF 420
QAPKTRSLDFPQNEPQIKNQFNKKLSGRLENTKQQLQLPLHPSWEASRRRKEQQSNIAVF
Sbjct: 361 QAPKTRSLDFPQNEPQIKNQFNKKLSGRLENTKQQLQLPLHPSWEASRRRKEQQSNIAVF 420
Query: 421 QGKKITFDD 429
QGKKITFDD
Sbjct: 421 QGKKITFDD 429
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 48.5 bits (114), Expect = 1e-05
Identities = 78/322 (24%), Positives = 127/322 (39%), Gaps = 38/322 (11%)
Query: 133 VESSKNASEDNHSENTLYSNDNGSNLQREATVISEQKVKETKILAKKPIHNSK------- 185
VE KN +++ H+ L + D +Q+E+ SEQK K T KKP N K
Sbjct: 287 VEEIKNYTKE-HNNLILLNKD----VQQES---SEQKNKSTDKGEKKPDSNEKGERKKEK 338
Query: 186 -EKIAK-MEHGPKAVTIANSPSKPSEKDSVVSLESQKTPADP---KLKTLSQTKKNKGS- 239
EK K +H K+ + K+ V ES K P++ K KT+ TK++
Sbjct: 339 KEKTEKKFDHSKKSEDTQKVKDEKQAKEKEV--ESLKLPSEKNSNKAKTVEGTKEDFSLI 396
Query: 240 DSSLSGNSD-GGEEFCEEEKEYFDDSTEERFYKQSSMSEDSDSGDDFFIGKVRRTR---- 294
DS + G +D + F++ TEE SM E + DD K +T+
Sbjct: 397 DSDVDGLTDITVSSVHTSDLSSFEEDTEEEVVTSDSMEEGEITSDDEEKNKQNKTKTQTS 456
Query: 295 -----KKESSCHSSVKEQKPLEKVFLKEDTGETHGDTRNDKIKPSTETRKLESVFFHSLS 349
K +S H+ V + K + D E + R I E R L
Sbjct: 457 DSSEGKTKSVRHAYVHKPYLYSKYYSDSD-DELTVEQRRQSIAKEKEERLLRRQINREKL 515
Query: 350 GSKSSRRNFKEQAPKTRSLDFPQNEPQIKNQFNKKLSGRLENTKQQL--QLPLHPSWEAS 407
K ++ K ++ KT+ ++ ++ K L + K+ L + L S
Sbjct: 516 EEKRKQKAEKTKSSKTKGQG--RSSVDLEESSTKSLEPKAARIKEVLKERKVLEKKVALS 573
Query: 408 RRRKEQQSNIAVFQGKKITFDD 429
++RK+ N+ KK +++
Sbjct: 574 KKRKKDSRNVEENSKKKQQYEE 595
Score = 45.4 bits (106), Expect = 1e-04
Identities = 86/358 (24%), Positives = 142/358 (39%), Gaps = 49/358 (13%)
Query: 9 LNNEVVKMRKEVKRIRVLVIRKLVRSVGRLKSKKGTEDALLKN-QRRAQRLLEEIHAMKE 67
L ++ + + E KR + K ++ G+ +S E++ K+ + +A R+ E + K
Sbjct: 506 LRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKSLEPKAARIKEVLKERKV 565
Query: 68 LKPDI-VTKSALGDDINFEKIFKKPDSTATERAIARLAVHPLLKKKIDVLKAAVQAFKEA 126
L+ + ++K D N E+ KK + LK K + + KE
Sbjct: 566 LEKKVALSKKRKKDSRNVEENSKKKQQYEEDSK-------ETLKTSEHCEKEKISSSKEL 618
Query: 127 RQNVAEVESSKNASEDNHSENTLYSNDNGSNLQRE------ATVISE------------Q 168
+ A+ E SK A + S + + N N S L+RE VI E +
Sbjct: 619 KHVHAKSEPSKPARRLSESLHVVDENKNESKLEREHKRRTSTPVIMEGVQEETDTRDVKR 678
Query: 169 KVKETKILAKKPIHNSKEKIAKMEHGPK---AVTIANSPSKPSEKDSVVSLESQKTPADP 225
+V+ ++I ++P K + +H K S K K S E +KTP++
Sbjct: 679 QVERSEICTEEP-QKQKSTLKNEKHLKKDDSETPHLKSLLKKEVKSSKEKPEREKTPSED 737
Query: 226 KLKTLSQTKKNKGSDSSLSGNSDGGEEFCEEEKEYFDDSTEERFYKQSSMSEDSDSGDDF 285
K LS K KG +G+ E EK EE KQS ++ S DD
Sbjct: 738 K---LSVKHKYKGDCMHKTGDE---TELHSSEKGL---KVEENIQKQSQQTK--LSSDD- 785
Query: 286 FIGKVRRTRKKESSCHSSV--KEQKPLEKVFLKEDTGETHGDTRNDKIKPSTETRKLE 341
K R K + SV K+ KP+ + +K D + + ++ + S E K E
Sbjct: 786 ---KTERKSKHRNERKLSVLGKDGKPVSEYIIKTDENVRKENNKKER-RLSAEKTKAE 839
Score = 35.0 bits (79), Expect = 0.13
Identities = 74/343 (21%), Positives = 132/343 (38%), Gaps = 59/343 (17%)
Query: 84 FEKIFKKPDSTAT----ERAIARLAVHPLLKKKIDVLKAAVQAFKEARQNVAEVESSKNA 139
+ K + D T ++IA+ LL+++I+ K +E R+ AE S
Sbjct: 477 YSKYYSDSDDELTVEQRRQSIAKEKEERLLRRQINREK-----LEEKRKQKAEKTKSSKT 531
Query: 140 SEDNHSENTLYSNDNGSNLQREATVISEQKVKETKILAKKPIHNSKEKIAKMEHGPKAVT 199
S L + S L+ +A I E +KE K+L KK + K K + V
Sbjct: 532 KGQGRSSVDLEESSTKS-LEPKAARIKEV-LKERKVLEKKVALSKKRK-----KDSRNVE 584
Query: 200 IANSPSKPSEKDSVVSLESQKTPADPKLKTLSQTKKNKGSDSSLSGNSDGGEEFCEEEKE 259
+ + E+DS +L++ + K+ + S+ K+ + S S + E E
Sbjct: 585 ENSKKKQQYEEDSKETLKTSEHCEKEKISS-SKELKHVHAKSEPSKPARRLSESLHVVDE 643
Query: 260 YFDDSTEERFYKQ--------SSMSEDSDSGDDFFIGKVRRTRKKESSCHSSVKEQKPLE 311
++S ER +K+ + E++D+ D V+R ++ C ++QK
Sbjct: 644 NKNESKLEREHKRRTSTPVIMEGVQEETDTRD------VKRQVERSEICTEEPQKQKSTL 697
Query: 312 K--VFLKEDTGET-------HGDTRNDKIKPSTETRKLESVF------------------ 344
K LK+D ET + ++ K KP E E
Sbjct: 698 KNEKHLKKDDSETPHLKSLLKKEVKSSKEKPEREKTPSEDKLSVKHKYKGDCMHKTGDET 757
Query: 345 -FHSLSGSKSSRRNFKEQAPKTRSLDFPQNEPQIKNQFNKKLS 386
HS N ++Q+ +T+ + E + K++ +KLS
Sbjct: 758 ELHSSEKGLKVEENIQKQSQQTKLSSDDKTERKSKHRNERKLS 800
Score = 28.9 bits (63), Expect = 9.4
Identities = 17/55 (30%), Positives = 27/55 (49%), Gaps = 6/55 (10%)
Query: 138 NASEDNHSENTLYSNDNGSNLQREATVISEQKVKETKILAKK------PIHNSKE 186
+AS D H EN L +++ N AT +S+ KV ++A+ P+ KE
Sbjct: 2341 SASIDRHEENQLTADNPEGNGDLSATEVSKHKVPMPSLIAENNCRCPGPVRGGKE 2395
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 47.4 bits (111), Expect = 3e-05
Identities = 47/243 (19%), Positives = 105/243 (43%), Gaps = 23/243 (9%)
Query: 9 LNNEVVKMRKEVKRIR------VLVIRKLVRSVGRLKSKKGTEDALLKNQRRAQRLLEEI 62
L E+V+++K+++ +R + +++K K K+ ED LK+ ++L+ E
Sbjct: 1942 LGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREF 2001
Query: 63 H---AMKELKPDIVTKSALGDDINFEKIFKKPDSTATERAIARLA------------VHP 107
+ A KE + ++ K + E + T + + ++A
Sbjct: 2002 NTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEE 2061
Query: 108 LLKKKIDVLKAAVQAFKEARQNVAEVESSKNASEDNHSENTLYSNDNGSNLQREATVISE 167
+L + + + A V+ + + + + K E+N + + + + L ++ T+IS+
Sbjct: 2062 ILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISD 2121
Query: 168 QKVKETKILAKKPIHNSKEKIAKMEHGPKAVTIANSPSKPSEKDSVVSLESQKTPADPKL 227
K+KE + ++ IHN ++++ K E A T+ + + VSL + T +
Sbjct: 2122 SKLKEQEF--REQIHNLEDRLKKYEKNVYATTVGTPYKGGNLYHTDVSLFGEPTEFEYLR 2179
Query: 228 KTL 230
K L
Sbjct: 2180 KVL 2182
Score = 29.6 bits (65), Expect = 5.5
Identities = 54/269 (20%), Positives = 105/269 (39%), Gaps = 50/269 (18%)
Query: 170 VKETKILAKKPIHNSKEKIAKMEHGPKAVTIANSPSKPSEKDSVVSLESQKTPADPKLKT 229
+ ETK + + +E+IA++ K +T + ++ +S++ + K
Sbjct: 366 IAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKE------KSERAAFEELEKA 419
Query: 230 LSQTKKNKGSDSSLSGNSDGG----EEFCEEEK---------------EYFDDSTEERFY 270
LS +K + + L D E+ EEE+ + S+EE+
Sbjct: 420 LSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIA 479
Query: 271 KQSSMSEDSDSGDDFFIGKVRRTRKKESSCHSSV---------------KEQKP---LEK 312
K + E + + + K +TR++E V KEQ+ LE+
Sbjct: 480 KLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEE 539
Query: 313 VFLKEDTGETHGDTRNDKIKPSTETRKLESVFFHSLSGSKSSRRNFKEQAPKTRSLDFPQ 372
+ L++ T + + ++ ET + + S S KS + N K +S D
Sbjct: 540 LELQKKAILTESENKLRDLQQEAETYRTRILELES-SLEKSLQEN------KNQSKDLAV 592
Query: 373 NEPQIKNQFNKKLSGRLENTKQQLQLPLH 401
+ KN+ NK+++ +E K +L+ H
Sbjct: 593 HLEAEKNKHNKEITVMVEKHKTELESLKH 621
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 44.3 bits (103), Expect = 2e-04
Identities = 61/256 (23%), Positives = 115/256 (44%), Gaps = 31/256 (12%)
Query: 28 IRKLVRSVGRLKSKKGTEDALLKNQRRAQRLLEEIHAMKELKPDIVTKSALGDDINF--E 85
+ +L + + K+ + EDA+ ++ + E + ++++ K T + L ++++ E
Sbjct: 1026 LEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQ---TNAKLQNELDTLKE 1082
Query: 86 KIFKKPDSTATERAIARLAVHPL--LKKKIDVLKAAVQAFKEARQNVAEVESSKNASEDN 143
K + + + + + +K+I+ LK A A K + + + E+ K A E
Sbjct: 1083 NNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAA-AQKSQQLSALQEENVKLAEELG 1141
Query: 144 HSENTLYSNDNGSNLQREATVISEQ----KVKETKILA-----KKPIHNS--------KE 186
S + + S+ L+ E +V++ Q K +E+K + K + S E
Sbjct: 1142 RSRDEVTSHQK---LEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTE 1198
Query: 187 KIAKMEHGPKAVTI--ANSPSKPSEKDSVVSLESQKTPADPKLKTLS-QTKKNKGSDSSL 243
K A++E VT+ + S S V +LES K + K+K L Q K+NK SS
Sbjct: 1199 KDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSS 1258
Query: 244 SGNSDGGEEFCEEEKE 259
SGN+D + E +E
Sbjct: 1259 SGNTDTQADEDERAQE 1274
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 44.3 bits (103), Expect = 2e-04
Identities = 61/256 (23%), Positives = 115/256 (44%), Gaps = 31/256 (12%)
Query: 28 IRKLVRSVGRLKSKKGTEDALLKNQRRAQRLLEEIHAMKELKPDIVTKSALGDDINF--E 85
+ +L + + K+ + EDA+ ++ + E + ++++ K T + L ++++ E
Sbjct: 1061 LEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQ---TNAKLQNELDTLKE 1117
Query: 86 KIFKKPDSTATERAIARLAVHPL--LKKKIDVLKAAVQAFKEARQNVAEVESSKNASEDN 143
K + + + + + +K+I+ LK A A K + + + E+ K A E
Sbjct: 1118 NNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAA-AQKSQQLSALQEENVKLAEELG 1176
Query: 144 HSENTLYSNDNGSNLQREATVISEQ----KVKETKILA-----KKPIHNS--------KE 186
S + + S+ L+ E +V++ Q K +E+K + K + S E
Sbjct: 1177 RSRDEVTSHQK---LEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTE 1233
Query: 187 KIAKMEHGPKAVTI--ANSPSKPSEKDSVVSLESQKTPADPKLKTLS-QTKKNKGSDSSL 243
K A++E VT+ + S S V +LES K + K+K L Q K+NK SS
Sbjct: 1234 KDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSS 1293
Query: 244 SGNSDGGEEFCEEEKE 259
SGN+D + E +E
Sbjct: 1294 SGNTDTQADEDERAQE 1309
>gi|21396500 HIRA interacting protein 3 [Homo sapiens]
Length = 556
Score = 43.9 bits (102), Expect = 3e-04
Identities = 38/163 (23%), Positives = 69/163 (42%), Gaps = 14/163 (8%)
Query: 185 KEKIAKMEHGPKAVTIANSPSKPSEKDSVVSLESQKTPADPKLKTLSQTKKNKGSDSSLS 244
+EK K + K V +P K S ES+++ A+P +T + + NKG+ S
Sbjct: 163 EEKGYKGKTRKKPVVKKQAPGKASVSRKQAREESEESEAEPVQRTAKKVEGNKGTKSLKE 222
Query: 245 GNSDGGEEFCEEEKEYFDDSTEERFYKQSSMSEDSDSGD---DFFIGKVRRTRKKESSCH 301
+ EE ++KE ++ EE ED + GD R++ ++E SC
Sbjct: 223 SEQESEEEILAQKKEQREEEVEE-----EEKEEDEEKGDWKPRTRSNGRRKSAREERSCK 277
Query: 302 SSVKEQKPLEKVFLKED------TGETHGDTRNDKIKPSTETR 338
+ ++ L +E+ +G+ G R ++ +E R
Sbjct: 278 QKSQAKRLLGDSDSEEEQKEAASSGDDSGRDREPPVQRKSEDR 320
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 42.4 bits (98), Expect = 8e-04
Identities = 48/236 (20%), Positives = 89/236 (37%), Gaps = 15/236 (6%)
Query: 131 AEVESSKNASEDNHSENTLYSNDNGSNLQREATVISEQKVKETKILAKKPIHNSKEKIAK 190
+ V ++K T Y N+ +R + +++K++ + +++P N EK
Sbjct: 76 SSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCV 135
Query: 191 MEHGP----KAVTIANSPSKPSEKDSVVSLESQKTPADPKLKTLSQTKKNKGSDSS-LSG 245
+ P K+ T S E D S SQ + + + + S SS G
Sbjct: 136 RKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQG 195
Query: 246 NSDGGEEFCEEEKEYFDDSTEERFYKQSSMSEDSDSGDDFFIGKVRRTRKKESSCHSSVK 305
N+ EE EE D+ EE + + ED + ++ + ++E +
Sbjct: 196 NNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDER 255
Query: 306 EQKPLEKVFLKEDTGETHGDTRNDKIKPSTETRKLESVFFHSLSGSKSSRRNFKEQ 361
+QK + G + DTR++ +E+ S SG+ S KE+
Sbjct: 256 DQK---------EEGNDY-DTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKER 301
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 42.0 bits (97), Expect = 0.001
Identities = 45/239 (18%), Positives = 89/239 (37%), Gaps = 6/239 (2%)
Query: 131 AEVESSKNASEDNHSENTLYSNDNGSNLQREATVISEQKVKETKILAKKPIHNSKEKIAK 190
AE + S + S+ N+S+ SN NG+N + K K + ++ +
Sbjct: 510 AEDDDSDSTSDTNNSD----SNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSD 565
Query: 191 MEHGPKAVTIANSPSKPSEKDSVVSLESQKTPADPKLKTLSQTKKNKGSDSSLSGNSDGG 250
+ + ++S S S+ DS S +S + + + + + SDSS S +S
Sbjct: 566 SSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSD 625
Query: 251 EEFCEEEKEYFDDSTEERFYKQSSMSEDSDSGDDFFIGKVRRTRKKESSCHSSVKEQKPL 310
E + D ++ S S++SDS D + +SS S
Sbjct: 626 SSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDS--SNSSNSSDSSDSSDSSDSSSSSDS 683
Query: 311 EKVFLKEDTGETHGDTRNDKIKPSTETRKLESVFFHSLSGSKSSRRNFKEQAPKTRSLD 369
D+ ++ + + S+++ +S + + S S N + + + S D
Sbjct: 684 SNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSD 742
Score = 38.1 bits (87), Expect = 0.015
Identities = 36/175 (20%), Positives = 64/175 (36%), Gaps = 6/175 (3%)
Query: 129 NVAEVESSKNASEDNHSENTLYSNDNGSNLQREATVISEQKVKETKILAKKPIHNSKEKI 188
N +E S ++S+ + S+++ SN N S+ + S + NS +
Sbjct: 697 NSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSS 756
Query: 189 AKMEHGPKAVTIANSPSKPSEKDSVVSLESQKTPADPKLKTLSQTKKNKGSDSSLSGNSD 248
+ +S S S S S S + ++ + + + SDSS S +S
Sbjct: 757 DSSDSSN------SSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSS 810
Query: 249 GGEEFCEEEKEYFDDSTEERFYKQSSMSEDSDSGDDFFIGKVRRTRKKESSCHSS 303
+ + + DS+ SS S DS D G + + S +SS
Sbjct: 811 DSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSS 865
Score = 34.3 bits (77), Expect = 0.22
Identities = 30/149 (20%), Positives = 56/149 (37%), Gaps = 13/149 (8%)
Query: 136 SKNASEDNHSENTLYSNDNGSNLQREATVISEQKVKETKILAKKPIHNSKEKIAKMEHGP 195
S ++S+ N S N+ S+D+ ++ +++ S +S + +
Sbjct: 879 SSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSS-------------DSSDSSNSSDSSE 925
Query: 196 KAVTIANSPSKPSEKDSVVSLESQKTPADPKLKTLSQTKKNKGSDSSLSGNSDGGEEFCE 255
+ + NS S S S S S + + + + + SDS+ S +SD
Sbjct: 926 SSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDS 985
Query: 256 EEKEYFDDSTEERFYKQSSMSEDSDSGDD 284
+ DS++ SS S DS D
Sbjct: 986 SDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1014
Score = 33.1 bits (74), Expect = 0.50
Identities = 33/150 (22%), Positives = 60/150 (40%), Gaps = 14/150 (9%)
Query: 134 ESSKNASEDNHSENTLYSNDNGSNLQREATVISEQKVKETKILAKKPIHNSKEKIAKMEH 193
+SSK+ S+ + S++ S+D+ S+ + + S+ NS +
Sbjct: 625 DSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSS-------------NSSNSSDSSDS 671
Query: 194 GPKAVTIANSPSKPSEKDSVVSLESQKTPADPKLKTLSQTKKNKGSDSSLSGNSDGGEEF 253
+ + ++S S S DS S +S + S + + SDSS S +SD
Sbjct: 672 SDSSDSSSSSDSSNSS-DSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSN 730
Query: 254 CEEEKEYFDDSTEERFYKQSSMSEDSDSGD 283
+ + + S S+ S+ SDS D
Sbjct: 731 SSDSSDSSNSSDSSDSSDSSNSSDSSDSSD 760
Score = 32.7 bits (73), Expect = 0.65
Identities = 39/236 (16%), Positives = 92/236 (38%), Gaps = 2/236 (0%)
Query: 135 SSKNASEDNHSENTLYSNDNGSNLQREATVISEQK-VKETKILAKKPIHNSKEKIAKMEH 193
S ++S+ + S+++ SN + S+ +++ S+ ++K + K +S + +K +
Sbjct: 583 SDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDS 642
Query: 194 GPKAVTIANSPSKPSEKDSVVSLESQKTPADPKLKTLSQTKKNKGSDSSLSGNSDGGEEF 253
+ ++ S S+ + S S + + + S + + SDSS S +S E
Sbjct: 643 SDSNSSDSSDNSDSSDSSNS-SNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSES 701
Query: 254 CEEEKEYFDDSTEERFYKQSSMSEDSDSGDDFFIGKVRRTRKKESSCHSSVKEQKPLEKV 313
+ DS++ S+ S+ S + +SS S+ +
Sbjct: 702 SDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS 761
Query: 314 FLKEDTGETHGDTRNDKIKPSTETRKLESVFFHSLSGSKSSRRNFKEQAPKTRSLD 369
D+ ++ + + S+++ + S S + S N + + + S D
Sbjct: 762 SNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSD 817
Score = 32.7 bits (73), Expect = 0.65
Identities = 32/156 (20%), Positives = 61/156 (39%), Gaps = 12/156 (7%)
Query: 129 NVAEVESSKNASEDNHSENTLYSNDNGSNLQREATVISEQKVKETKILAKKPIHNSKEKI 188
N ++ +S ++S+ N S+++ SN + S+ +++ S+ NS +
Sbjct: 958 NSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSS----------NSSDSS 1007
Query: 189 AKMEHGPKAVTIANSPSKPSEKDSVVSLESQKTPADPKLKTLSQTKKNKGSDSSLSGNSD 248
+ + + +S S S S S S + + + + + SDSS S +S
Sbjct: 1008 DSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1067
Query: 249 GGEEFCEEEKEYFDDSTEERFYKQSSMSEDSDSGDD 284
+ + DS+E SS S DS D
Sbjct: 1068 DSSDSSDSSDS--SDSSESSDSSDSSNSSDSSDSSD 1101
Score = 32.3 bits (72), Expect = 0.85
Identities = 32/150 (21%), Positives = 54/150 (36%), Gaps = 2/150 (1%)
Query: 135 SSKNASEDNHSENTLYSNDNGSNLQREATVISEQKVKETKILAKKPIHNSKEKIAKMEHG 194
S N+S+ + S N+ S+D+ + + S + NS + +
Sbjct: 969 SDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSS 1028
Query: 195 PKAVTIANSPSKPSEKDSVVSLESQKTPADPKLKTLSQTKKNKGSDSSLSGNSDGGEEFC 254
+ + +S S S S S S + + + + + SDSS S SD E
Sbjct: 1029 NSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS--SDSSESSD 1086
Query: 255 EEEKEYFDDSTEERFYKQSSMSEDSDSGDD 284
+ DS++ SS S DS D
Sbjct: 1087 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1116
Score = 32.0 bits (71), Expect = 1.1
Identities = 42/241 (17%), Positives = 84/241 (34%), Gaps = 16/241 (6%)
Query: 129 NVAEVESSKNASEDNHSENTLYSNDNGSNLQREATVISEQKVKETKILAKKPIHNSKEKI 188
N ++ S N+S+ ++S ++ S+D+ + ++ S + +S
Sbjct: 790 NSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSD 849
Query: 189 AKMEHGPKAVTIANSPSKPSEKDSVVSLESQKTPADPKLKTLSQTKKNKGSDSSLSGNSD 248
+NS DS S S + + ++ + + + S+SS S +SD
Sbjct: 850 GSDSDSSNRSDSSNSSDSSDSSDS--SNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSD 907
Query: 249 GGEEFCEEEKEYFDDSTEERFYKQSSMSEDSDSGDDFFIGKVRRTRKKESSCHSSVKEQK 308
+ DS+E +S S DS + D +SS S+ +
Sbjct: 908 SSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSD----------SSDSSDSSNSSDSS 957
Query: 309 PLEKVFLKEDTGETHGDTRNDKIKPSTETRKLESVFFHSLSGSKSSRRNFKEQAPKTRSL 368
D+ +++ +D S + +S S S S N + + + S
Sbjct: 958 NSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDS----SDSSDSSDSSNSSDSSDSSDSS 1013
Query: 369 D 369
D
Sbjct: 1014 D 1014
Score = 32.0 bits (71), Expect = 1.1
Identities = 31/162 (19%), Positives = 60/162 (37%), Gaps = 6/162 (3%)
Query: 129 NVAEVESSKNASEDNHSENTL-YSNDNGSNLQREATVISEQKVKETKILAKKPIHNSKEK 187
N ++ S N+S+ + S N+ SN + S+ +++ S+ + ++S
Sbjct: 910 NSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSS 969
Query: 188 IAKMEHGPKAVTIANSPSKPSEKDSVVSLESQKTP-----ADPKLKTLSQTKKNKGSDSS 242
+ + ++S DS S +S + +D + S N S+
Sbjct: 970 DSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSN 1029
Query: 243 LSGNSDGGEEFCEEEKEYFDDSTEERFYKQSSMSEDSDSGDD 284
S +SD + + DS++ SS S DS D
Sbjct: 1030 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1071
Score = 31.6 bits (70), Expect = 1.4
Identities = 30/150 (20%), Positives = 56/150 (37%), Gaps = 1/150 (0%)
Query: 135 SSKNASEDNHSENTLYSNDNGSNLQREATVISEQKVKETKILAKKPIHNSKEKIAKMEHG 194
SS ++ + S+++ SN + SN ++ S+ + +S + +
Sbjct: 764 SSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNS 823
Query: 195 PKAVTIANSPSKPSEKDSVVSLESQKTPADPKLKTLSQTKKNKGSDSSLSGNS-DGGEEF 253
+ ++S + DS S +S + + SDSS S NS D +
Sbjct: 824 SDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSS 883
Query: 254 CEEEKEYFDDSTEERFYKQSSMSEDSDSGD 283
E DS++ S S+ S+S D
Sbjct: 884 DSNESSNSSDSSDSSNSSDSDSSDSSNSSD 913
Score = 31.2 bits (69), Expect = 1.9
Identities = 29/154 (18%), Positives = 63/154 (40%), Gaps = 4/154 (2%)
Query: 131 AEVESSKNASEDNHSENTLYSNDNGSNLQREATVISEQKVKETKILAKKPIHNSKEKIAK 190
++ S N+S+ + S N+ S+ + S+ +++ S ++ + +++ +
Sbjct: 883 SDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSS--DSSESSNSSDNSNSSDSSN 940
Query: 191 MEHGPKAVTIANSPSKPSEKDSVVSLESQKTPADPKLKTLSQTKKNKGSDSSLSGNSDGG 250
+ +NS + DS S +S + + + + + + SDSS S SD
Sbjct: 941 SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDS--SDSS 998
Query: 251 EEFCEEEKEYFDDSTEERFYKQSSMSEDSDSGDD 284
+ + DS++ SS S DS + D
Sbjct: 999 DSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSD 1032
Score = 30.8 bits (68), Expect = 2.5
Identities = 30/161 (18%), Positives = 60/161 (37%), Gaps = 7/161 (4%)
Query: 131 AEVESSKNASEDNHSENTLYSNDNGSNLQREATVISEQKVKETKILAKKPIHNSKEKIAK 190
++ +S ++S+ + S ++ S+D+ ++ + S + NS +
Sbjct: 977 SDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDS 1036
Query: 191 MEHGPKAVTIANSPSKPSEKDSVVSLESQKTPADPKLKTLSQTKKNKGSDSSLSGNS--- 247
+ + + +S S S S S S + + + + ++ SDSS S NS
Sbjct: 1037 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDS 1096
Query: 248 ----DGGEEFCEEEKEYFDDSTEERFYKQSSMSEDSDSGDD 284
D + + DS++ SS S DS D
Sbjct: 1097 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1137
Score = 30.8 bits (68), Expect = 2.5
Identities = 30/155 (19%), Positives = 58/155 (37%), Gaps = 1/155 (0%)
Query: 131 AEVESSKNASEDNHSENTLYSNDNGSNLQREATVISEQKVKETKILAKKPIHNSKEKIAK 190
++ S ++S+ + S N+ S+D+ + + S ++ +S +
Sbjct: 1106 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDS 1165
Query: 191 MEHGPKAVTIANSPSKPSEKDSVVSLESQKTPADPKLKTLSQTKKNKGSDSS-LSGNSDG 249
+ + + +S S S S S S + + + + + SDSS S +SD
Sbjct: 1166 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1225
Query: 250 GEEFCEEEKEYFDDSTEERFYKQSSMSEDSDSGDD 284
+ E DS++ SS S DS D
Sbjct: 1226 SDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSD 1260
Score = 30.4 bits (67), Expect = 3.2
Identities = 29/137 (21%), Positives = 47/137 (34%), Gaps = 9/137 (6%)
Query: 200 IANSPSKPSEKDSVVSLESQKTPADPKLKTLSQTKKNKGSDSSLSGNSDGGEEFCEEEKE 259
I NS + + K + + T ++ G D+S S G + E+E
Sbjct: 200 IENSCRNEGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGS 259
Query: 260 YFDDSTEERFYKQSSMSEDSDSGDDFFIGKVRRTRKKESSCHSSVKEQKPLEKVFLKEDT 319
D+ E K SS + G D KE SS+ + ++ + E
Sbjct: 260 GDDEDEEAGNGKDSSNNSKGQEGQD---------HGKEDDHDSSIGQNSDSKEYYDPEGK 310
Query: 320 GETHGDTRNDKIKPSTE 336
+ H + DK S E
Sbjct: 311 EDPHNEVDGDKTSKSEE 327
Score = 30.0 bits (66), Expect = 4.2
Identities = 27/151 (17%), Positives = 56/151 (37%), Gaps = 4/151 (2%)
Query: 134 ESSKNASEDNHSENTLYSNDNGSNLQREATVISEQKVKETKILAKKPIHNSKEKIAKMEH 193
+SS ++ N S+++ S+ + SN + + ++ + + +
Sbjct: 949 DSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSD 1008
Query: 194 GPKAVTIANSPSKPSEKDSVVSLESQKTPADPKLKTLSQTKKNKGSDSSLSGNSDGGEEF 253
+ +NS + DS S +S +D + S + S S +SD +
Sbjct: 1009 SSDSSDSSNSSDSSNSSDSSNSSDS----SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1064
Query: 254 CEEEKEYFDDSTEERFYKQSSMSEDSDSGDD 284
+ DS++ +SS S DS + D
Sbjct: 1065 DSSDSSDSSDSSDSSDSSESSDSSDSSNSSD 1095
Score = 28.9 bits (63), Expect = 9.4
Identities = 28/156 (17%), Positives = 59/156 (37%), Gaps = 8/156 (5%)
Query: 129 NVAEVESSKNASEDNHSENTLYSNDNGSNLQREATVISEQKVKETKILAKKPIHNSKEKI 188
N ++ S ++S+ ++S ++ S+D+ ++ + S + NS +
Sbjct: 1002 NSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1061
Query: 189 AKMEHGPKAVTIANSPSKPSEKDSVVSLESQKTPADPKLKTLSQTKKNKGSDSSLSGNSD 248
+ + + +S S S + S S S + + + + + SDSS S +S
Sbjct: 1062 DSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1121
Query: 249 GGEEFCEEEKEYFDDSTEERFYKQSSMSEDSDSGDD 284
+ DS++ SS S DS +
Sbjct: 1122 NSSDS--------SDSSDSSDSSDSSNSSDSSDSSE 1149
Score = 28.9 bits (63), Expect = 9.4
Identities = 29/155 (18%), Positives = 57/155 (36%), Gaps = 1/155 (0%)
Query: 131 AEVESSKNASEDNHSENTLYSNDNGSNLQREATVISEQKVKETKILAKKPIHNSKEKIAK 190
++ S ++SE + S ++ S+D+ + + S + +S +
Sbjct: 1073 SDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1132
Query: 191 MEHGPKAVTIANSPSKPSEKDSVVSLESQKTPADPKLKTLSQTKKNKGSDSS-LSGNSDG 249
+ + + +S S S S S S + + + + + SDSS S +SD
Sbjct: 1133 SDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1192
Query: 250 GEEFCEEEKEYFDDSTEERFYKQSSMSEDSDSGDD 284
+ + DS++ SS S DS D
Sbjct: 1193 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1227
>gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]
Length = 1007
Score = 41.6 bits (96), Expect = 0.001
Identities = 60/251 (23%), Positives = 98/251 (39%), Gaps = 16/251 (6%)
Query: 122 AFKEARQNVAEVESSKNASEDNHSENTLYSNDNGSNLQREATVISEQKVKETKILAKKPI 181
A E N E S++ S++ HS + + + S ++ E K K+ K K
Sbjct: 18 ANSEKSINEENGEVSEDQSQNKHSRHKKKKHKHRSKHKKHKHSSEEDKDKKHKHKHKHKK 77
Query: 182 HNSKEKIAKMEHGPKAVTIANSPSKPSEKDSVV---SLESQKTPADPKLKT-LSQTKKNK 237
H KE I + SP+K ++ D + LE Q+ +L L + K
Sbjct: 78 HKRKEIIDASDKE------GMSPAKRTKLDDLALLEDLEKQRALIKAELDNELMEGKVQS 131
Query: 238 GSDSSLSGNSDGGEEFCEEEKEYFDDSTEERFYKQSSMSEDSDSGDDFFIGKVR-RTRKK 296
G L G G EE E ++ + + + SS + D+ K R ++R K
Sbjct: 132 GMGLILQGYESGSEEEGEIHEKARNGNRSST--RSSSTKGKLELVDNKITTKKRSKSRSK 189
Query: 297 ESSCHSSVKEQKPLEKVFLKEDTGETHGDTRNDKIKPSTETRKLESVFFHSLSGSKSSRR 356
E + H S K++ +KE T + R PS ++ + S S + RR
Sbjct: 190 ERTRHRSDKKKSKGGIEIVKEKTTRSKSKERKKSKSPSKRSKSQDQA---RKSKSPTLRR 246
Query: 357 NFKEQAPKTRS 367
+E+ K RS
Sbjct: 247 RSQEKIGKARS 257
Score = 29.3 bits (64), Expect = 7.2
Identities = 42/218 (19%), Positives = 79/218 (36%), Gaps = 19/218 (8%)
Query: 33 RSVGRLKSKKG----TEDALLKNQRRAQRLLEEIHAMKELKP-----DIVTKSALGDDIN 83
RS R S KG ++ + +R R E + K +IV +
Sbjct: 159 RSSTRSSSTKGKLELVDNKITTKKRSKSRSKERTRHRSDKKKSKGGIEIVKEKTTRSKSK 218
Query: 84 FEKIFKKPDSTATERAIARLAVHPLLKKKIDVLKAAVQAFKEARQNVAEVESSKNASEDN 143
K K P + + AR + P L+++ ++ + + + + SK+ + +
Sbjct: 219 ERKKSKSPSKRSKSQDQARKSKSPTLRRRSQEKIGKARSPTDDKVKIEDKSKSKDRKK-S 277
Query: 144 HSENTLYSNDNGSNLQREATVISEQKVKETKILAKKPIHNSKEKIAKMEHGPKAVTIANS 203
N S D G + + + K + ++ SKE+ +K K S
Sbjct: 278 PIINESRSRDRGKKSRSPVDLRGKSKDRRSR---------SKERKSKRSETDKEKKPIKS 328
Query: 204 PSKPSEKDSVVSLESQKTPADPKLKTLSQTKKNKGSDS 241
PSK + S++ PK ++LS ++K S
Sbjct: 329 PSKDASSGKENRSPSRRPGRSPKRRSLSPKPRDKSRRS 366
>gi|32484979 adaptor-related protein complex 3, beta 1 subunit [Homo
sapiens]
Length = 1094
Score = 41.2 bits (95), Expect = 0.002
Identities = 45/172 (26%), Positives = 72/172 (41%), Gaps = 16/172 (9%)
Query: 203 SPSKPSEKDSVVSLESQKTPADPKLKTLSQTKK--------NKGSDSSLSGNSDGGEEFC 254
+P V+ L + TPA K K + KK SDSS S+ G E
Sbjct: 643 APDPSVRNVEVIELAKEWTPAG-KAKQENSAKKFYSESEEEEDSSDSSSDSESESGSESG 701
Query: 255 EEEKEYFDDSTEERFYKQSSMSEDSDSGDDFFIGKVRRTRKKESSCHSSVKEQKPLEKVF 314
E+ + + + E + SS +DS+SG + + + +RT K+ S + + EK
Sbjct: 702 EQGESGEEGDSNEDSSEDSSSEQDSESGRESGL-ENKRTAKRNSKAKGK-SDSEDGEKEN 759
Query: 315 LKEDTGETHGDTRNDKIKPSTETRKLESVFFHSLSGSKSSRRNFKEQAPKTR 366
K T ++ D + I+ S+ + ES SRR KE+ KT+
Sbjct: 760 EKSKTSDSSND-ESSSIEDSSSDSESES----EPESESESRRVTKEKEKKTK 806
Score = 33.9 bits (76), Expect = 0.29
Identities = 34/149 (22%), Positives = 59/149 (39%), Gaps = 22/149 (14%)
Query: 263 DSTEERFYKQSSMSEDS-DSGDDFFIGKVRRTRKKESSCHSSVKEQKPLEKVFLKEDTGE 321
+++ ++FY +S EDS DS D ES S EQ ++GE
Sbjct: 669 ENSAKKFYSESEEEEDSSDSSSD-----------SESESGSESGEQG---------ESGE 708
Query: 322 THGDTRNDKIKPSTETRKLESVFFHSLSGSKSSRRNFKEQAPKTRSLDFPQNEPQIKNQF 381
GD+ D + S+ + ES L ++++RN K + +NE +
Sbjct: 709 -EGDSNEDSSEDSSSEQDSESGRESGLENKRTAKRNSKAKGKSDSEDGEKENEKSKTSDS 767
Query: 382 NKKLSGRLENTKQQLQLPLHPSWEASRRR 410
+ S +E++ + P E+ RR
Sbjct: 768 SNDESSSIEDSSSDSESESEPESESESRR 796
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 41.2 bits (95), Expect = 0.002
Identities = 70/300 (23%), Positives = 122/300 (40%), Gaps = 28/300 (9%)
Query: 132 EVESSKNASEDNHSENTLYSNDNGSNLQREATVISEQKVKETKILAKKPIHNSKEKIAKM 191
E E SK S+ + L ND + + + K+ + L+K + KE + K
Sbjct: 660 EYEDSKQKSD----KAILLENDLSTENKLKVLKHDRDHFKKEEKLSKMKLEE-KEWLFKD 714
Query: 192 EHGPKAVTIAN---SPSKPSEKDSVVSLESQ-----KTPADPKLKTLSQT--KKNKGSDS 241
E K + N S S EKD E + K+P + KL+ + KK+K S
Sbjct: 715 EKSLKRIKDTNKDISRSFREEKDRSNKAEKERSLKEKSPKEEKLRLYKEERKKKSKDRPS 774
Query: 242 SLSGNSDGGEEFCEEEKEYFDDSTEERFYKQSSMSEDSDSGDDFFIGKVRRTRKKESSCH 301
L +D E+ +EKE +E+ K+ E DS D + K + + E +
Sbjct: 775 KLEKKNDLKEDKISKEKEKIFKEDKEKLKKEKVYRE--DSAFDEYCNK-NQFLENEDTKF 831
Query: 302 SSVKEQKPLEKVFLKEDTGETHGDTRNDKIKPSTETRKLESVFFHSL------SGSKSSR 355
S +Q+ L + + + G+ D P T+ R ++S L SK R
Sbjct: 832 SLSDDQRDRWFSDLSDSSFDFKGEDSWD--SPVTDYRDMKSDSVAKLILETVKEDSKERR 889
Query: 356 RNFKEQAPKTRSLDFPQNEPQIKNQFNKKLSGRLENTKQQLQLPLHPSWEASRRRKEQQS 415
R+ +A + R P + ++ +K R E T++ +P + S + +RR+ ++
Sbjct: 890 RD--SRAREKRDYREPFFRKKDRDYLDKNSEKRKEQTEKHKSVPGYLSEKDKKRRESAEA 947
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 41.2 bits (95), Expect = 0.002
Identities = 50/217 (23%), Positives = 87/217 (40%), Gaps = 28/217 (12%)
Query: 121 QAFKEARQNVAEVESSKNASED------NHSENTLYSNDNGSNLQREATVISEQKVKETK 174
QA + + + S + SED + SEN S+ + E ++ E +
Sbjct: 233 QASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENE 292
Query: 175 ILAKKPIHNSKEKIAKMEHGPKAVTIANSPSKPSEKDSVVSLESQKTPADPKLKTLSQTK 234
L K + +S+ + GP+ P+ SE + S QK +D +
Sbjct: 293 ELPKPRVSDSESE------GPQ-----KGPASDSETEDA-SRHKQKPESDD-----DSDR 335
Query: 235 KNKGSDSSLSGNSDGGEEFCEEEKEYFDDSTEERFYKQSSMS-EDSDSGDDFFIGKVRRT 293
+NKG D+ + +S + + +K + DS EE KQ S ED G++ + K
Sbjct: 336 ENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEEEEHKKQKMDSDEDEKEGEEEKVAK---- 391
Query: 294 RKKESSCHSSVKEQKPLEKVFLKEDTGETHGDTRNDK 330
RK S +E+ +K + D ++ D +DK
Sbjct: 392 RKAAVLSDSEDEEKASAKKSRVVSDADDSDSDAVSDK 428
Score = 40.0 bits (92), Expect = 0.004
Identities = 54/205 (26%), Positives = 90/205 (43%), Gaps = 40/205 (19%)
Query: 124 KEARQNVAEVESSKNASEDNHSENTLYSNDN---GSNLQREATVISEQKVKETKILAKKP 180
++A ++ + ES ++ +N E+T ND+ S++ R+ S+ + +E K
Sbjct: 318 EDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEEEEHKKQKMDS 377
Query: 181 IHNSKEKIAKMEHGPKAVTIANSPS--KPSEKDSVVSLESQKTPADP-------KLKTLS 231
+ KE + KA +++S K S K S V ++ + +D + KT++
Sbjct: 378 DEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSDSDAVSDKSGKREKTIA 437
Query: 232 QT-----------KKNK-----GSDSSLSGNSDG-------GEEFCEEEKEYF----DDS 264
KKN+ GSDS SGN + GE EEE+E+ +D
Sbjct: 438 SDSEEEAGKELSDKKNEEKDLFGSDSE-SGNEEENLIADIFGESGDEEEEEFTGFNQEDL 496
Query: 265 TEERFYKQSSMSEDSDSGDDFFIGK 289
EE+ Q +EDSDS D+ GK
Sbjct: 497 EEEKGETQVKEAEDSDSDDNIKRGK 521
>gi|4507241 structure specific recognition protein 1 [Homo sapiens]
Length = 709
Score = 41.2 bits (95), Expect = 0.002
Identities = 46/195 (23%), Positives = 82/195 (42%), Gaps = 21/195 (10%)
Query: 110 KKKIDVLKAAVQAFKEARQNVAEVESSKNASED-----------NHSENTLYSNDNG--- 155
KK+ + KA + +++R+ EV+ K+ + N S + S+ G
Sbjct: 515 KKRKQLKKAKMAKDRKSRKKPVEVKKGKDPNAPKRPMSAYMLWLNASREKIKSDHPGISI 574
Query: 156 SNLQREATVISEQKVKETKILAKKPIHNSK---EKIAKMEHGPKAVTIANSPSKPSEKDS 212
++L ++A I + KE K + +++ EK K G + + SK +K
Sbjct: 575 TDLSKKAGEIWKGMSKEKKEEWDRKAEDARRDYEKAMKEYEGGRGESSKRDKSKKKKKVK 634
Query: 213 VVSLESQKTPA---DPKLKTLSQTKKNKGSDSSLSGNSDGGEEFCEEEKEYFDDSTEERF 269
V +E + TP+ K + ++ K + S S GE ++++ +DS EE
Sbjct: 635 V-KMEKKSTPSRGSSSKSSSRQLSESFKSKEFVSSDESSSGENKSKKKRRRSEDSEEEEL 693
Query: 270 YKQSSMSEDSDSGDD 284
SEDS SG D
Sbjct: 694 ASTPPSSEDSASGSD 708
Score = 34.7 bits (78), Expect = 0.17
Identities = 27/105 (25%), Positives = 42/105 (40%), Gaps = 3/105 (2%)
Query: 207 PSEKDSVVSLESQKTPADPKLKTLSQTKKNKGSDSSLSGNSDGGEEFCEEEKEYFDDSTE 266
PS + S E Q ++K + ++ +DSS + E F E+E +
Sbjct: 436 PSYDEYADSDEDQHDAYLERMKEEGKIREENANDSSDDSGEETDESFNPGEEE---EDVA 492
Query: 267 ERFYKQSSMSEDSDSGDDFFIGKVRRTRKKESSCHSSVKEQKPLE 311
E F +S S S+ GD K R+ KK +KP+E
Sbjct: 493 EEFDSNASASSSSNEGDSDRDEKKRKQLKKAKMAKDRKSRKKPVE 537
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 41.2 bits (95), Expect = 0.002
Identities = 50/216 (23%), Positives = 90/216 (41%), Gaps = 22/216 (10%)
Query: 124 KEARQNVA--EVESSKNASEDNHSENTLYSNDNGSNLQREATVISEQKVKETKILAKKPI 181
K R+N A + +S N+ D + S+ + + EAT SE +V E I K
Sbjct: 874 KPKRKNYAGSKWDSESNSERDVTKNSKNDSHPSSDKEEGEATSDSESEVSEIHIKVKPTT 933
Query: 182 HNS---------------KEKIAKMEHGPKAVTIANSPSKPSEKDSVVSLESQKTPADPK 226
+S K++ + + N+ KP +K S E+ K K
Sbjct: 934 KSSTNTSLPDDNGAWKSSKQRTSTSDSEGSCSNSENNRGKP-QKHKHGSKENLKREHTKK 992
Query: 227 LKTLSQTKKNKGSDSSLSGNSDGGE---EFCEEEKEYFDDSTEERFYKQSSMSEDSDSGD 283
+K + KK+K + + + EF EEE+E DD + K+ +SE++++
Sbjct: 993 VKEKLKGKKDKKHKAPKRKQAFHWQPPLEFGEEEEEEIDDKQVTQESKEKKVSENNETIK 1052
Query: 284 DFFIGKVRRTRKKESSCHSSVKEQKPLEKVFLKEDT 319
D + + + + S H +V L++ F K+D+
Sbjct: 1053 DNILKTEKSSEEDLSGKHDTVTVSSDLDQ-FTKDDS 1087
Score = 31.6 bits (70), Expect = 1.4
Identities = 63/318 (19%), Positives = 120/318 (37%), Gaps = 52/318 (16%)
Query: 84 FEKIFKKP-----------DSTATERAIARLAVHPLLKKKIDVLKAAVQAFKEARQNVAE 132
FEK KKP S+++E + H +++ + V+ K+ R+ +
Sbjct: 185 FEKKRKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASS 244
Query: 133 VESSKNASEDN---HSE--NTLYSNDNGSNLQREATVISEQK---VKETKILAKKPIHNS 184
E +N N HSE +T S+ +RE V+ ++ V E + L ++ +
Sbjct: 245 SEEPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPPVPENRFLLRRDM--- 301
Query: 185 KEKIAKMEHGPKAVTIAN--SPSKPSEKDSVVSLESQKT---PADPKLKTLSQTKKNKGS 239
+ E PK +A S KPS S ++ + T P+ ++ S++ + S
Sbjct: 302 --PVVTAEPEPKIPDVAPIVSDQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDDDDSS 359
Query: 240 DSSLSGNSD----------GGEEFCEEEKEYFDDSTEERFYKQSSMSEDSDSGDDFFIGK 289
++ + GE++ + +K D R+ ++S + +
Sbjct: 360 ETPPHWKEEMQRLRAYRPPSGEKWSKGDK--LSDPCSSRWDERSLSQRSRSWSYNGYYSD 417
Query: 290 VRRTRKKESSCHSSVKEQKPLEKVFLKEDTGETHGDTRNDKIKPSTETRKLESVFFHSLS 349
+ R HS +++ EK + G+ R K +T+K + +
Sbjct: 418 LSTAR------HSGHHKKRRKEKKVKHKKKGKKQKHCRRHK-----QTKKRRILIPSDIE 466
Query: 350 GSKSSRRNFKEQAPKTRS 367
SKSS R K + RS
Sbjct: 467 SSKSSTRRMKSSCDRERS 484
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 40.8 bits (94), Expect = 0.002
Identities = 68/380 (17%), Positives = 145/380 (38%), Gaps = 23/380 (6%)
Query: 50 KNQRRAQRLLEEIHAM-KELKPDIVTKSALGDDINFEKIFKKPDSTATERAIARLAVHPL 108
+ +RR Q + I + +E ++ S D +K +K + +A L +PL
Sbjct: 199 ETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPVAPLIPYPL 258
Query: 109 LKK-----------KIDVLKAAVQAFKEARQNVAEVESSKNASEDNHSENTLYSNDNGSN 157
+ K K D++ + F++ + + E E K E E +
Sbjct: 259 ITKEDINAIEMEEDKRDLISREISKFRDTHKKLEE-EKGKKEKERQEIEKERRERERERE 317
Query: 158 LQREATVISEQKVKETKILAKKPIHNSKEKIAKMEHGPKAVTIANSPSKPSEKDSVVSLE 217
+RE ++ +E + +K +E+ + K + ++D S +
Sbjct: 318 RERERREREREREREREREKEKERERERERDRDRDR-TKERDRDRDRERDRDRDRERSSD 376
Query: 218 SQKTPADPKLKTLSQTKKNKGSDSSLSGNSDGGEEFCEEEKEYFDDSTEERFYKQSSMSE 277
K + + K+ + ++ + E E E+E + E+ K+ +
Sbjct: 377 RNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREED 436
Query: 278 DSDSGDDFFIGKVRRTRKKESSCHSSVK--EQKPLEKVFLKEDTGETHGDTRNDKIKPST 335
+ D+ + + R+ R+KE++ +K E + +K E E + R + K
Sbjct: 437 EEDAYERRKLE--RKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAK--- 491
Query: 336 ETRKLESVFFHSLSGSKSSRRNFKEQAPKTRSLDFPQNEPQIKNQFNKKLSGRLENTKQQ 395
E ++L+ F + + ++ A + R D + E + + K+ LE +Q+
Sbjct: 492 EAKRLKE-FLEDYDDDRDDPKYYRGSALQKRLRD-REKEMEADERDRKREKEELEEIRQR 549
Query: 396 LQLPLHPSWEASRRRKEQQS 415
L HP +A +R EQ++
Sbjct: 550 LLAEGHPDPDAELQRMEQEA 569
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
sapiens]
Length = 1341
Score = 40.4 bits (93), Expect = 0.003
Identities = 61/286 (21%), Positives = 108/286 (37%), Gaps = 45/286 (15%)
Query: 50 KNQRRAQRLLEEIHAMKELKPDIVTKSALGDDINFEKIFKKPDSTATERAIARLAVHPLL 109
K RRA L H +K+ ++S+ + + PDS+ + + PL
Sbjct: 555 KEGRRASHTLLPSHRLKQSADSSSSRSSSSSSSSSRSRSRSPDSSGSR------SHSPLR 608
Query: 110 KKKIDVLKAAVQAFKEARQNVAEVESSKNASEDNHSENTLYSNDNGS---NLQREATV-- 164
K+ DV +A A R + +S++ S + SN S + R+++
Sbjct: 609 SKQRDVAQARTHANPRGRPKMGSRSTSESRSRSRSRSRSASSNSRKSLSPGVSRDSSTSY 668
Query: 165 -----------ISEQKVKETKILAKKPIHNSKE------KIAKMEHGPKAVTIANSPSKP 207
++ V + ++ K ++ ++++ E K VT P +
Sbjct: 669 TETKDPSSGQEVATPPVPQLQVCEPKERTSTSSSSVQARRLSQPESAEKHVTQRLQPERG 728
Query: 208 SEKDSVVSLESQKTPADPKLKTLSQTKKNKGSDSSLSGNSDGGEEFCEEEKEYFDDSTEE 267
S K + + A+P T QT + + S S+ EE++E D++E
Sbjct: 729 SPK------KCEAEEAEPPAATQPQTSETQTSHLP---ESERIHHTVEEKEEVTMDTSEN 779
Query: 268 RFYKQSSMSE------DSDSGDDFFIGKVRRTRKKESSCHSSVKEQ 307
R ++ + E D S DD G V KKESS S K +
Sbjct: 780 R--PENDVPEPPMPIADQVSNDDRPEGSVEDEEKKESSLPKSFKRK 823
>gi|117938307 doublecortin domain containing 2 [Homo sapiens]
Length = 476
Score = 40.4 bits (93), Expect = 0.003
Identities = 39/166 (23%), Positives = 75/166 (45%), Gaps = 17/166 (10%)
Query: 136 SKNASEDNHSENTLYSNDNGS--NLQREATVISEQKVKETKILAKKPIHNSKEKIAKMEH 193
SK + D HS++T+ S+DN S L+R+ K TK+ + NS+E I +
Sbjct: 250 SKGSGNDRHSKSTVGSSDNSSPQPLKRKGKKEDVNSEKLTKLKQNVKLKNSQETIPNSDE 309
Query: 194 GPKAVTIANSPSK-----PSEKDSVVSLESQKTPADPKLKTLSQTKKNKGSD-----SSL 243
G S ++ ++D+ V + + PA+ + K NK ++ S +
Sbjct: 310 GIFKAGAERSETRGAAEVQEDEDTQVEVPVDQRPAEIVDEEEDGEKANKDAEQKEDFSGM 369
Query: 244 SGN--SDGGEEFC---EEEKEYFDDSTEERFYKQSSMSEDSDSGDD 284
+G+ +GG E E+ +E D S ++ + + D ++G++
Sbjct: 370 NGDLEEEGGREATDAPEQVEEILDHSEQQARPARVNGGTDEENGEE 415
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 40.0 bits (92), Expect = 0.004
Identities = 74/380 (19%), Positives = 151/380 (39%), Gaps = 53/380 (13%)
Query: 24 RVLVIRKLVRSVGRLKSKKGTEDALLKNQRRAQRLLEEIHAMKELKPDIVTKSALGDDIN 83
R+L + + + G+L+ +G + ++ QR+ + ++ +E S +
Sbjct: 2022 RILAMEESEIAKGKLEFTRG-QRIFVQGQRKLAKASRKLIKKRE--------SLSKEPAK 2072
Query: 84 FEKIFKKPDS-TATERAIARLAVHPLLKKKIDVLKAAVQAFKEARQNVAEVESSKNASED 142
KI K T ER + + + K+ +K + ++++ ++ E + S+ SE
Sbjct: 2073 LNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSEL 2132
Query: 143 NHSENTLYSNDNG-SNLQREATVISEQKVKETKILAKKPIH-----------NSKEKIAK 190
E L +N R E+ +E LA+K +E I
Sbjct: 2133 TKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPF 2192
Query: 191 MEHGPKAVTIANSPSKPSEKDS--VVSLESQKTPADPKLKTLSQTKKNKGSDSSLSGNSD 248
++ + A KP EK S V +ES++ ++ L + +K + S
Sbjct: 2193 LKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSS------- 2245
Query: 249 GGEEFCEEEKEYFDDSTEERFYKQSSMSEDSDSGDDFFIGKVRRTRKKESSCHSSVKEQK 308
EE EEE+E ++ EE ++ ++ + G++ + K +KK+ K++K
Sbjct: 2246 --EE--EEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKK-------KKEK 2294
Query: 309 PLEKVFLKEDTGETHGDTRNDKIKPSTETRKLESVFFHSLSGSKSSRRNFKEQAPKTRSL 368
E+V KE+ E ++I ET L S + + +E+ + + +
Sbjct: 2295 KKEEVQEKEEVFE-----EKEEIMSEEETESL------SDEEEEEESCSLEEEVDREKEI 2343
Query: 369 DFPQNEPQIKNQFNKKLSGR 388
+ + +++ Q K L GR
Sbjct: 2344 LKKEKQFKLQEQRRKSLRGR 2363
Score = 28.9 bits (63), Expect = 9.4
Identities = 45/217 (20%), Positives = 84/217 (38%), Gaps = 16/217 (7%)
Query: 200 IANSPSKPSEKDSV-VSLESQKTPADPKLKTLSQTKKNKGSDSSLSGNSDGGEEF---CE 255
+A PSK + V SQK K KT + K ++ L + G E E
Sbjct: 1074 VAIKPSKGQRRGQAGVKKHSQKWLRGLK-KTKERDSKQMSTEPGLLEDESGTEAAPIEME 1132
Query: 256 EEKEYFDDSTEERFYKQSSM--SEDSDSGDDFFIGKVRRTRKKESSCHSSVKEQKPLEKV 313
E Y S+ K S S++ D D ++R +K QK +K
Sbjct: 1133 EASVYSQWSSSTSVIKLSKDVDSQEKDISKDHIALTLKRLQKIRDKRDKKATAQKLKKKH 1192
Query: 314 FLKEDTGETHGDTRNDKI--KPSTETRKLESVFFHSLSGSKSSR---RNFKEQAPKTRSL 368
K + + + +P T+ K++ +SG +S+ ++++ + +L
Sbjct: 1193 KKKGKEAKVINEETTPPVMEQPVTKKVKIQGRGASGISGRRSTAGDGSSWRDDLCRLMAL 1252
Query: 369 DFPQNEPQIKNQFNKKLSGRLENTKQQLQLPLHPSWE 405
++ ++ ++ L+ L Q++ + HPSWE
Sbjct: 1253 RISGSQTKM----SENLNAELVTFAQEMLVDRHPSWE 1285
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 40.0 bits (92), Expect = 0.004
Identities = 64/295 (21%), Positives = 114/295 (38%), Gaps = 34/295 (11%)
Query: 28 IRKLVRSVGRLKSKKGTEDALLKNQRRAQRLLEEIHAMKELKPDIVTKSALGDDINFEKI 87
+++ +S + KS + + +K+ EE + + P+ KS + +++ +
Sbjct: 740 VKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPE-KAKSPVKEEVKSPEK 798
Query: 88 FKKP---DSTATERAIARL--AVHPLLKKKIDVLKAAVQAFKEARQNVAEVESSKNASED 142
K P D+ A E+ I + P+ +++ + K+A + A +D
Sbjct: 799 AKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKD 858
Query: 143 NHSENTLYSNDNGSNLQREATVISEQKVKETKILAKKPIHNSKEKIAKMEHGPKAVTIAN 202
+ E ++ + E K KE+K+ AKK K+K+ E A
Sbjct: 859 SKKEEAPKKEAPKPKVEEKKEPAVE-KPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVK 917
Query: 203 SPSKPSEKDSVVSLESQKTPADPKLKTLSQTKKNKGSDSSLSGNSDGGEEFCEEEKEYFD 262
+KP EK V ++K P D K K S+ + K E E+K
Sbjct: 918 EDAKPKEKTEV----AKKEPDDAKAKEPSKPAEKK--------------EAAPEKK---- 955
Query: 263 DSTEERFYK--QSSMSEDSDSGDDFFIGK---VRRTRKKESSCHSSVKEQKPLEK 312
D+ EE+ K + +E DD + K + K E S + K+ KP EK
Sbjct: 956 DTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEK 1010
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 40.0 bits (92), Expect = 0.004
Identities = 66/326 (20%), Positives = 131/326 (40%), Gaps = 37/326 (11%)
Query: 117 KAAVQAFKEARQNVAEVESSKNASEDNHSENTLY--SNDNGSNLQREATVIS-EQKVKET 173
K A + K+ ++NV + + K+ +D S + S D + +++ + + K K+T
Sbjct: 304 KDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDT 363
Query: 174 KILAK---------KPIHNSKEKIAKMEHGP------KAVTIANSP-----SKPSEKDSV 213
K + K N + K K +T + SK S+KD
Sbjct: 364 KKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEK 423
Query: 214 VSLESQKTPADPKLKTLSQTKKNKGSDSSLSGNSDGGEEFCEEEKEYFDDSTEERFYKQS 273
+ KT D K K++ +++ +DS G+S G++ +E+K D +++
Sbjct: 424 KDKKDSKT--DNK-KSVKNDEESTDADSEPKGDSKKGKK--DEKKGKKDSKKDDKKKDAK 478
Query: 274 SMSEDSDSGDDFFIGKVRRTRKKESSCHSSVKE--QKPLEKVFLKEDTGETHGDTRNDKI 331
+E ++ D + K ++ K++ +K+ +K E + D G + KI
Sbjct: 479 KNAESTEMESDLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKI 538
Query: 332 KPSTETRKLESVF----FHSLSGSKSSRRNFK-EQAPKTRSLDFPQNEPQIKNQFNKKLS 386
K S +T ES++ + S + N K E R + + K +
Sbjct: 539 KGS-DTESEESLYKPGAKKKIDESDGTSANSKMEGLESKRGFRMSSKKTTFNEKGEKAST 597
Query: 387 GRLENTKQQLQLP-LHPSWEASRRRK 411
GR+ ++++ LP PS + + R+
Sbjct: 598 GRVPPSREKPPLPACEPSLPSPKVRR 623
Score = 37.7 bits (86), Expect = 0.020
Identities = 65/303 (21%), Positives = 120/303 (39%), Gaps = 26/303 (8%)
Query: 127 RQNVAEVESSKNASEDNHSENTL---------YSNDNGSNLQREATVISEQKVKETKILA 177
++++ ++S + + SEN+L S+D N S+ K +
Sbjct: 221 KKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKY 280
Query: 178 KKPIHNSKEKIAKMEHGPKAVTIANSPSKPSEKDSVVSLESQKTPADPKLKTLSQTKKNK 237
K +K AK K+ + SK ++KDS ++ K D K K + KK+
Sbjct: 281 TKYTKKDTKKNAK-----KSSDAESEDSKDAKKDSKKVKKNVKK--DDKKKDV---KKDT 330
Query: 238 GSDSSLSGNSDGGEEFCEEEKEYFDDSTEERFYKQSSMSEDSDSGDDFFIGKVRRTRKKE 297
S + SG+S + +++K+ +++ K+ S D++SGD R KK
Sbjct: 331 ESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKA 390
Query: 298 SSCHSSVKEQKPLEKVFLKE---DTGETHGDTRNDKIKPSTETRKLESVFFHSLSGSKSS 354
S K+ K + E ++ E+ D + DK T+ +K SV S S
Sbjct: 391 SKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKK--SVKNDEESTDADS 448
Query: 355 RRNFKEQAPKTRSLDFPQNEPQIKNQFNKKLSGRLENTKQQLQLPLHPSWEASRRRKEQQ 414
K + K + + + K+ K E+T+ + L L + S+ +K +
Sbjct: 449 EP--KGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSKEKKGSK 506
Query: 415 SNI 417
+I
Sbjct: 507 KDI 509
Score = 34.3 bits (77), Expect = 0.22
Identities = 52/230 (22%), Positives = 82/230 (35%), Gaps = 35/230 (15%)
Query: 161 EATVISEQKVKETKILAKKPIHNS------KEKIAKMEHGPKAVTIANSPSKPSEKDSVV 214
E+ I E+K K K P+ +S K+ + E P++ S+KD
Sbjct: 143 ESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQKDKKD 202
Query: 215 SLESQKTPADPKLKTLSQTKKNKGSDSSLSGNS-DGGEEFCEEEKEYFD------DSTEE 267
S S+KT + TK N D S S D E C E D S +E
Sbjct: 203 SKNSKKTNTE-----FLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDDE 257
Query: 268 --------RFYKQSSMSEDSDSGDDFFIGKVRRTRKKESSCHSSVKEQKPLEKVFLKEDT 319
R Y Q++ S + ++ KK S S + + +K++
Sbjct: 258 SINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNV 317
Query: 320 GETHGDTRNDKIKPSTETRKLESVFFHSLSGSKSSRRNFKEQAPKTRSLD 369
+ D + +K TE+ ES SK R++ K+ K + D
Sbjct: 318 KK---DDKKKDVKKDTESTDAES------GDSKDERKDTKKDKKKLKKDD 358
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 40.0 bits (92), Expect = 0.004
Identities = 31/155 (20%), Positives = 69/155 (44%), Gaps = 4/155 (2%)
Query: 28 IRKLVRSVGRLKSKKGTEDALLKNQRRAQRLLEEIHAMKELKPDIVTKSALGDDINFEKI 87
I +L RSV ++ L K+ + Q + +H +EL P++ S + +N ++
Sbjct: 1251 IDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELEL 1310
Query: 88 FKKPDSTATERAIARLAVHPL-LKKKIDVLKAAVQAFKEARQNVAEVESSKNASED---N 143
+ +T +AR+ + L L +K + +++ + R N+ ++ + D
Sbjct: 1311 LTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKE 1370
Query: 144 HSENTLYSNDNGSNLQREATVISEQKVKETKILAK 178
H TL + Q ++ + E+ + TKI+++
Sbjct: 1371 HIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSE 1405
Score = 32.7 bits (73), Expect = 0.65
Identities = 77/414 (18%), Positives = 170/414 (41%), Gaps = 56/414 (13%)
Query: 40 SKKGTEDALLKNQRRA-----QRLLEEIHAMKELKPDIVTKSALGDDINFEKIFKKPDST 94
S+K TE + ++ Q A Q ++EI+ KE + +I S + + +N K FK+
Sbjct: 1501 SEKETEISTIQKQLEAINDKLQNKIQEIYE-KEEQFNIKQISEVQEKVNELKQFKE-HRK 1558
Query: 95 ATERAIARLAVHPL-LKKKIDVLKAAVQAFKEARQNVAEVESSKNASEDNHSENTLYSND 153
A + A+ + L L ++ + +Q + ++ + V+ + D ENT
Sbjct: 1559 AKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENT----- 1613
Query: 154 NGSNLQREATVISEQKVKETKILAKKPIHNSKEKIAKMEHGPKAVTIANSPSKPSEKDSV 213
+ + E + KE + L ++ ++EK+ ++EH + + E +++
Sbjct: 1614 -----KEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENI 1668
Query: 214 -------VSLESQK--TPADPKLKTLSQTKK------NKGSDSSLSGNSDGGEEF----- 253
+LE + T L+++ +T K + +++ + + EE
Sbjct: 1669 RLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHM 1728
Query: 254 -CEEEKEYFD---DSTEERFYKQSSMSEDSDSGDDFFIGKVRRTRKKESSCHSSVKE-QK 308
+E +E D E+ + S+M +D + +D + + +++ H +KE Q+
Sbjct: 1729 HLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQE 1788
Query: 309 PLEKV--FLKEDTGETHG---DTRNDKIKPSTETRKLESVFFHSLSGSKSSRRNFKEQAP 363
++K+ + E T + D N K + ++L++ ++ K K+ +
Sbjct: 1789 TIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVS- 1847
Query: 364 KTRSLDFPQNEPQIKNQFNKKLSGRLENTKQQLQLPLHPSWEASRRRKEQQSNI 417
+ Q + QIK+Q +LE L LH + E + +++ N+
Sbjct: 1848 -----EMEQLKKQIKDQ--SLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNL 1894
>gi|47578107 delangin isoform B [Homo sapiens]
Length = 2697
Score = 40.0 bits (92), Expect = 0.004
Identities = 53/246 (21%), Positives = 93/246 (37%), Gaps = 28/246 (11%)
Query: 132 EVESSKNASEDNHSENTLYSND---NGSNLQREATVISEQKVKETKILAKKPIHNSKEKI 188
++ S ++ +NH E +D + S +++ + ++E K E +++ K N E
Sbjct: 584 DIVGSLKSTPENHPETPKKKSDPELSKSEMKQSESRLAESKPNENRLVETKSSENKLET- 642
Query: 189 AKMEHGPKAVTIANSPSKPSEKDSVVSLESQKTPADPKLKT--LSQTKKNKGSDSSLSGN 246
V K +E + +++ T +PK LS TK N ++ G
Sbjct: 643 --------KVETQTEELKQNESRTTECKQNESTIVEPKQNENRLSDTKPNDNKQNN--GR 692
Query: 247 SDGGEEFCEEEKEYFDDSTEERFYKQSSMSEDSDSGDDFFIGKVRRTRKKESSCHSSVKE 306
S+ + E K+ + E K E D G+ ++K S +
Sbjct: 693 SETTKSRPETPKQKGESRPETPKQKSDGHPETPKQKGD---GRPETPKQKGES-----RP 744
Query: 307 QKPLEKVFLKEDTGETHGDTRNDKIKPSTETRKLESVFFHSLSGS----KSSRRNFKEQA 362
+ P +K + +T + D R D KPSTE + S KS R +Q
Sbjct: 745 ETPKQKNEGRPETPKHRHDNRRDSGKPSTEKKPEVSKHKQDTKSDSPRLKSERAEALKQR 804
Query: 363 PKTRSL 368
P RS+
Sbjct: 805 PDGRSV 810
>gi|47578105 delangin isoform A [Homo sapiens]
Length = 2804
Score = 40.0 bits (92), Expect = 0.004
Identities = 53/246 (21%), Positives = 93/246 (37%), Gaps = 28/246 (11%)
Query: 132 EVESSKNASEDNHSENTLYSND---NGSNLQREATVISEQKVKETKILAKKPIHNSKEKI 188
++ S ++ +NH E +D + S +++ + ++E K E +++ K N E
Sbjct: 584 DIVGSLKSTPENHPETPKKKSDPELSKSEMKQSESRLAESKPNENRLVETKSSENKLET- 642
Query: 189 AKMEHGPKAVTIANSPSKPSEKDSVVSLESQKTPADPKLKT--LSQTKKNKGSDSSLSGN 246
V K +E + +++ T +PK LS TK N ++ G
Sbjct: 643 --------KVETQTEELKQNESRTTECKQNESTIVEPKQNENRLSDTKPNDNKQNN--GR 692
Query: 247 SDGGEEFCEEEKEYFDDSTEERFYKQSSMSEDSDSGDDFFIGKVRRTRKKESSCHSSVKE 306
S+ + E K+ + E K E D G+ ++K S +
Sbjct: 693 SETTKSRPETPKQKGESRPETPKQKSDGHPETPKQKGD---GRPETPKQKGES-----RP 744
Query: 307 QKPLEKVFLKEDTGETHGDTRNDKIKPSTETRKLESVFFHSLSGS----KSSRRNFKEQA 362
+ P +K + +T + D R D KPSTE + S KS R +Q
Sbjct: 745 ETPKQKNEGRPETPKHRHDNRRDSGKPSTEKKPEVSKHKQDTKSDSPRLKSERAEALKQR 804
Query: 363 PKTRSL 368
P RS+
Sbjct: 805 PDGRSV 810
>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 39.7 bits (91), Expect = 0.005
Identities = 53/252 (21%), Positives = 100/252 (39%), Gaps = 26/252 (10%)
Query: 95 ATERAIARLAVHPLLKKKIDVLKAAVQAFKEARQNVAEVESSKNASEDNHSENTLYSNDN 154
A E A P+ +KK + + + + A +N A+ S + +E+ E ++
Sbjct: 413 AQETATGMAFEEPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEAEEGCPEK---ESEE 469
Query: 155 GSNLQREATVISEQKVKETKILAKKPIHNSKEKIAKMEHGPKAVTI---ANSPSKPSEKD 211
G + S+++ +E P+ S+E K E K + N +K SE D
Sbjct: 470 GCPKRGFEGSCSQKESEEGN-----PVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDD 524
Query: 212 SVVSLESQKTPADPKLKTLSQTKKNKGSDSSLSGNSDGGEEFCEE---EKEYFDDSTEER 268
++ ES++ K ++K D S + DG E EE EK+ ++ +E+
Sbjct: 525 --LNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKE 582
Query: 269 FYK----------QSSMSEDSDSGDDFFIGKVRRTRKKESSCHSSVKEQKPLEKVFLKED 318
++ S SE D G + + + R+ + +E+ EKVF E
Sbjct: 583 LHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDES 642
Query: 319 TGETHGDTRNDK 330
+ + ++K
Sbjct: 643 DEKEDEEYADEK 654
Score = 33.9 bits (76), Expect = 0.29
Identities = 43/168 (25%), Positives = 71/168 (42%), Gaps = 35/168 (20%)
Query: 124 KEARQNVAEVESSKNASE-----DNHSENTLYSNDNGSNLQREATVISEQKVKETKILAK 178
KE +NV + E +N SE D+ SE L ++ GS +RE S++K +E K
Sbjct: 581 KELHENVLDKELEENDSENSEFEDDGSEKVL--DEEGS--EREFDEDSDEKEEEEDTYEK 636
Query: 179 KPIHNSKEKIAKMEHGPKAVTIANSPSKPSEKDSVVSLESQKTPADPKLKTLSQTKKNKG 238
S EK + K + A+ ++ + AD KL S K+++
Sbjct: 637 VFDDESDEKEDEEYADEKGLEAADKKAEEGD-------------ADEKLFEESDDKEDE- 682
Query: 239 SDSSLSGNSDGGEEFCEEEKEYFDDSTEERFYKQSSMSEDSDSGDDFF 286
++DG E +EK + DD + E+ + E+ DS + F
Sbjct: 683 -------DADGKEVEDADEKLFEDDDSNEKLF-----DEEEDSSEKLF 718
>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 39.7 bits (91), Expect = 0.005
Identities = 53/252 (21%), Positives = 100/252 (39%), Gaps = 26/252 (10%)
Query: 95 ATERAIARLAVHPLLKKKIDVLKAAVQAFKEARQNVAEVESSKNASEDNHSENTLYSNDN 154
A E A P+ +KK + + + + A +N A+ S + +E+ E ++
Sbjct: 413 AQETATGMAFEEPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEAEEGCPEK---ESEE 469
Query: 155 GSNLQREATVISEQKVKETKILAKKPIHNSKEKIAKMEHGPKAVTI---ANSPSKPSEKD 211
G + S+++ +E P+ S+E K E K + N +K SE D
Sbjct: 470 GCPKRGFEGSCSQKESEEGN-----PVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDD 524
Query: 212 SVVSLESQKTPADPKLKTLSQTKKNKGSDSSLSGNSDGGEEFCEE---EKEYFDDSTEER 268
++ ES++ K ++K D S + DG E EE EK+ ++ +E+
Sbjct: 525 --LNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKE 582
Query: 269 FYK----------QSSMSEDSDSGDDFFIGKVRRTRKKESSCHSSVKEQKPLEKVFLKED 318
++ S SE D G + + + R+ + +E+ EKVF E
Sbjct: 583 LHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDES 642
Query: 319 TGETHGDTRNDK 330
+ + ++K
Sbjct: 643 DEKEDEEYADEK 654
Score = 33.9 bits (76), Expect = 0.29
Identities = 43/168 (25%), Positives = 71/168 (42%), Gaps = 35/168 (20%)
Query: 124 KEARQNVAEVESSKNASE-----DNHSENTLYSNDNGSNLQREATVISEQKVKETKILAK 178
KE +NV + E +N SE D+ SE L ++ GS +RE S++K +E K
Sbjct: 581 KELHENVLDKELEENDSENSEFEDDGSEKVL--DEEGS--EREFDEDSDEKEEEEDTYEK 636
Query: 179 KPIHNSKEKIAKMEHGPKAVTIANSPSKPSEKDSVVSLESQKTPADPKLKTLSQTKKNKG 238
S EK + K + A+ ++ + AD KL S K+++
Sbjct: 637 VFDDESDEKEDEEYADEKGLEAADKKAEEGD-------------ADEKLFEESDDKEDE- 682
Query: 239 SDSSLSGNSDGGEEFCEEEKEYFDDSTEERFYKQSSMSEDSDSGDDFF 286
++DG E +EK + DD + E+ + E+ DS + F
Sbjct: 683 -------DADGKEVEDADEKLFEDDDSNEKLF-----DEEEDSSEKLF 718
>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 2 [Homo sapiens]
Length = 1403
Score = 39.3 bits (90), Expect = 0.007
Identities = 76/400 (19%), Positives = 163/400 (40%), Gaps = 61/400 (15%)
Query: 42 KGTEDALLKNQRRAQRLLEEIHAMKELKPD--IVTKSALGDDIN-FEKIFKKPDSTATER 98
K + DA++ + R + + + K+L+ + ++ +L D++ E +F P+ E
Sbjct: 741 KKSHDAIIDDLNRKLLDVTQKYTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEI 800
Query: 99 AIARLAVHPL------LKKKIDVLKAAVQAFKEARQNVAEVESSKNASEDNHSENTLYSN 152
+ + L LKKK + + A N+ ++ S++ H E + N
Sbjct: 801 IALKSNIVELKKQLSELKKKCGEDQEKIHALTSENTNLKKMMSNQYVPVKTHEEVKMTLN 860
Query: 153 DNGSNLQREATVISEQ---------KVKETKILAKKPIHNSK-----EKIAKMEHGPKAV 198
D + RE + ++ K+K+ + K+ + N++ E I+ EH K
Sbjct: 861 DTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMS 920
Query: 199 TIANSPSKPSE------------KDSVVSLESQKTPADPKLKTLSQTKKNKGSDSSLSGN 246
+++ S K + ++ +V+L ++ +L T+ + K K + +
Sbjct: 921 SLSQSMRKVQDSNAEILANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVK--YAPIVSF 978
Query: 247 SDGGEEFCEEEKEYFDDSTEERFYKQSSMSEDSDSGDDFFIGKVRRTRKKESSCHSSV-K 305
+ +F EKE D +E+ ++ S+SE+ +V++ +++ +
Sbjct: 979 EECERKFKATEKELKDQLSEQT--QKYSVSEE----------EVKKNKQENDKLKKEIFT 1026
Query: 306 EQKPL-EKVFLKEDTGETHGDTRNDKIKPSTETRKLESVFFHSLSGSKSSRRNFKEQAPK 364
QK L +K L E ++H R K ++L+ + + +E A +
Sbjct: 1027 LQKDLRDKTVLIE---KSHEMERALSRKTDELNKQLKDLSQKYTEVKNVKEKLVEENAKQ 1083
Query: 365 TRSLDFPQNEPQIKN-------QFNKKLSGRLENTKQQLQ 397
T + QN Q ++ K L+G +EN K++L+
Sbjct: 1084 TSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELK 1123
>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 1 [Homo sapiens]
Length = 1416
Score = 39.3 bits (90), Expect = 0.007
Identities = 76/400 (19%), Positives = 163/400 (40%), Gaps = 61/400 (15%)
Query: 42 KGTEDALLKNQRRAQRLLEEIHAMKELKPD--IVTKSALGDDIN-FEKIFKKPDSTATER 98
K + DA++ + R + + + K+L+ + ++ +L D++ E +F P+ E
Sbjct: 754 KKSHDAIIDDLNRKLLDVTQKYTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEI 813
Query: 99 AIARLAVHPL------LKKKIDVLKAAVQAFKEARQNVAEVESSKNASEDNHSENTLYSN 152
+ + L LKKK + + A N+ ++ S++ H E + N
Sbjct: 814 IALKSNIVELKKQLSELKKKCGEDQEKIHALTSENTNLKKMMSNQYVPVKTHEEVKMTLN 873
Query: 153 DNGSNLQREATVISEQ---------KVKETKILAKKPIHNSK-----EKIAKMEHGPKAV 198
D + RE + ++ K+K+ + K+ + N++ E I+ EH K
Sbjct: 874 DTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMS 933
Query: 199 TIANSPSKPSE------------KDSVVSLESQKTPADPKLKTLSQTKKNKGSDSSLSGN 246
+++ S K + ++ +V+L ++ +L T+ + K K + +
Sbjct: 934 SLSQSMRKVQDSNAEILANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVK--YAPIVSF 991
Query: 247 SDGGEEFCEEEKEYFDDSTEERFYKQSSMSEDSDSGDDFFIGKVRRTRKKESSCHSSV-K 305
+ +F EKE D +E+ ++ S+SE+ +V++ +++ +
Sbjct: 992 EECERKFKATEKELKDQLSEQT--QKYSVSEE----------EVKKNKQENDKLKKEIFT 1039
Query: 306 EQKPL-EKVFLKEDTGETHGDTRNDKIKPSTETRKLESVFFHSLSGSKSSRRNFKEQAPK 364
QK L +K L E ++H R K ++L+ + + +E A +
Sbjct: 1040 LQKDLRDKTVLIE---KSHEMERALSRKTDELNKQLKDLSQKYTEVKNVKEKLVEENAKQ 1096
Query: 365 TRSLDFPQNEPQIKN-------QFNKKLSGRLENTKQQLQ 397
T + QN Q ++ K L+G +EN K++L+
Sbjct: 1097 TSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELK 1136
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 39.3 bits (90), Expect = 0.007
Identities = 60/270 (22%), Positives = 109/270 (40%), Gaps = 36/270 (13%)
Query: 47 ALLKNQRRAQRLLEEI-HAMKELKPDIVTKSALGDDINFEK---IFKKPDSTATERAIAR 102
A+L+ +L +++ A +EL + S L + N+EK FK+ S R
Sbjct: 985 AVLQKTELENKLQQQLTQAAQELAAEKEKISVLQN--NYEKSQETFKQLQSDFYGRESEL 1042
Query: 103 LAVHPLLKKKIDVLKAAVQAFKEARQNVAEVESSKNASEDNHSENTLYSNDNGSNLQREA 162
LA LK + L A + R + +K E ++ TL + Q +
Sbjct: 1043 LATRQDLKSVEEKLSLAQEDLISNRNQIGN--QNKLIQELKTAKATLEQDSAKKEQQLQE 1100
Query: 163 TVISEQKVKETKILAKKPIHNSKEKIAKME----HGPKAVTIANSPSKPSEKDSVVSLES 218
+ Q +++ K L +K + N K K+A++E K +T N K + +S+ + +
Sbjct: 1101 RCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITN 1160
Query: 219 QKTPADPKLKTLSQTKKNKGSDSSLSGNSDGGEEFCEEEKEYFDDSTEERFYKQSSMSED 278
K D K + Q + L G +D + E+EK ++ K E+
Sbjct: 1161 LK---DAKQLLIQQKLE-------LQGKADSLKAAVEQEKR------NQQILKDQVKKEE 1204
Query: 279 SDSGDDFFIGKVRRTRKKESSCHSSVKEQK 308
+ +F +KE+ HS +KE++
Sbjct: 1205 EELKKEFI--------EKEAKLHSEIKEKE 1226
Score = 33.5 bits (75), Expect = 0.38
Identities = 69/330 (20%), Positives = 130/330 (39%), Gaps = 44/330 (13%)
Query: 112 KIDVLKAAVQAFKEARQNVAEVESSKNASEDNH---SENTLYSNDNGSNLQREATVISEQ 168
++D+ K + +A + +Q + + E K + + S+ T ++ +N + + TV Q
Sbjct: 785 RLDLQKKS-EALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNN-RIQTTVTELQ 842
Query: 169 KVKETKILAKKPIHNSKEKIAKMEHGPKAVTIANSPS---KPSEKDSVVSLESQKTPADP 225
KVK K + K+K++K+ ++ NS S K ++K L+ +KT +
Sbjct: 843 KVKMEKEALMTELSTVKDKLSKVSD-----SLKNSKSEFEKENQKGKAAILDLEKTCKEL 897
Query: 226 KLKTLSQTKKNKGSDSSLSGNSDGGEEFCEEEKEYFDDSTE-----ERFYKQSSMSEDSD 280
K + Q + L + + +E + K + E + KQ+ E
Sbjct: 898 KHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQL 957
Query: 281 SGDDFFIGKVRRTRKK-----ESSCHSSVKEQKPLEKVFLKEDT---------GETHGDT 326
G+ + + +KK + +V ++ LE ++ T E
Sbjct: 958 QGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVL 1017
Query: 327 RNDKIKPSTETRKLESVFFHSLSGSKSSRRNFK--EQAPKTRSLDFPQNEPQIKNQFNKK 384
+N+ K ++L+S F+ S ++R++ K E+ D N QI NQ K
Sbjct: 1018 QNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQ--NK 1075
Query: 385 LSGRLENTKQQLQLPLHPSWEASRRRKEQQ 414
L L+ K L E +KEQQ
Sbjct: 1076 LIQELKTAKATL--------EQDSAKKEQQ 1097
>gi|38788333 remodeling and spacing factor 1 [Homo sapiens]
Length = 1441
Score = 38.9 bits (89), Expect = 0.009
Identities = 70/371 (18%), Positives = 139/371 (37%), Gaps = 35/371 (9%)
Query: 80 DDINFEKIFKKPDSTATERAIARLAVHPLLKKKIDVLKAAVQAFKEARQNVAEVESSKNA 139
D +++ I + + A A+ + + P+L K + + + E
Sbjct: 184 DGSSWKCIVRNRNELAETLALLKAQIDPVLLKNSSQQDNSSRESPSLEDEETKKEEETPK 243
Query: 140 SEDNHSENTLYSNDNGSNLQREAT--VISEQKVK----ETKILAKKPIHNSKEKIAKMEH 193
E+ + S + +L+ +T V+ E VK + K L K P+ EK
Sbjct: 244 QEEQKESEKMKSEEQPMDLENRSTANVLEETTVKKEKEDEKELVKLPVIVKLEKPLPENE 303
Query: 194 GPKAVTIANSPSKPSEKDSVVSLESQKTPADPKLKTLSQTKKNKGSDS---SLSGNSDGG 250
K + + K + K + +E ++ ADPK T S +K + GN
Sbjct: 304 EKKIIKEESDSFKENVKP--IKVEVKECRADPK-DTKSSMEKPVAQEPERIEFGGNIKSS 360
Query: 251 EEFCE---EEKEYFDDSTEERFYKQSSMSEDSDSGDDFFIGKVRR--TRKKESSCHSSVK 305
E E EE E + + + + + SD D G + + T KE +
Sbjct: 361 HEITEKSTEETEKLKNDQQAKIPLKKREIKLSDDFDSPVKGPLCKSVTPTKEFLKDEIKQ 420
Query: 306 EQKPLEKVFLKEDTGE-----THGDTRNDKIKPSTETRKLESVFFHSL--SGSKSSRRNF 358
E++ +++ G +G+ ++++ P+ +T +E+ F+ + S S S RN
Sbjct: 421 EEETCKRISTITALGHEGKQLVNGEVSDERVAPNFKTEPIETKFYETKEESYSPSKDRNI 480
Query: 359 KEQAPKTRSL----------DFPQNEPQIKNQFNKKLSG-RLENTKQQLQLPLHPSWEAS 407
+ T SL + + ++ + +S + + K Q++ P P E S
Sbjct: 481 ITEGNGTESLNSVITSMKTGELEKETAPLRKDADSSISVLEIHSQKAQIEEPDPPEMETS 540
Query: 408 RRRKEQQSNIA 418
E +++
Sbjct: 541 LDSSEMAKDLS 551
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 38.9 bits (89), Expect = 0.009
Identities = 72/343 (20%), Positives = 131/343 (38%), Gaps = 33/343 (9%)
Query: 36 GRLKSKKGTEDALLKNQRRAQRLLEEIHAMKEL-------KPDIVTKSALGDDINFEKIF 88
G +++ E+A K +++ + EE+ +EL KP+ + +
Sbjct: 569 GETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKS 628
Query: 89 KKPDSTATERAIARLAVHPLLKK-KIDVLKAAVQAFKEARQNVAEVESS------KNASE 141
P S E+ + + P+ +K K V K+ V+ ++ + + VE K+ E
Sbjct: 629 PVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVE 688
Query: 142 DNHSENTLYSNDNGSNLQREATVISEQKVKETKILAKKPIHNSK--EKIAKMEHGPKAVT 199
+ S+ + + ++E +++ E K K + K E K E + VT
Sbjct: 689 EAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVT 748
Query: 200 IANSPSKPSEKDS-------VVSLESQKTPADPKLKTLSQTKKNKGS---DSSLSGNSDG 249
I S EK++ E +K + + K KGS D +++G +G
Sbjct: 749 ITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEG 808
Query: 250 GEEFCEEEKEYFDDSTEERFYKQSSMS---EDSDSGDDFFIGKVRRTRKKES-SCHSSVK 305
EE +E KE EE+ + + D G D KV T+ E +
Sbjct: 809 KEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGGDG 868
Query: 306 EQKPLEKVFLKEDTGETHGDTRNDKIKPSTETRKLESVFFHSL 348
K + K E H +T +K+ T+K+E V H++
Sbjct: 869 ATKYITKSVTVTQKVEEHEETFEEKL---VSTKKVEKVTSHAI 908
Score = 35.4 bits (80), Expect = 0.10
Identities = 53/251 (21%), Positives = 93/251 (37%), Gaps = 19/251 (7%)
Query: 125 EARQNVAEVESSKNA---SEDNHSENTLYSNDNGSNLQREATVISEQKVKETKILAKKPI 181
EA AE + K SE+ ++ L ++ ++ + + + V+E K P+
Sbjct: 574 EAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEK---GKSPV 630
Query: 182 HNSKEKIAKMEHGPKAVTI--ANSPSKPSEKDSVVSLESQKTPADPKLKTLSQTKKNKGS 239
S + PK+ SP S + K+P + K K S K+
Sbjct: 631 PKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAK--SPVPKSPVE 688
Query: 240 DSSLSGNSDGGEEFCEEEKEYFDDSTEERFYKQSSMSED--------SDSGDDFFIGKVR 291
++ GE+ EEEKE + EE+ K+ +D S ++ V
Sbjct: 689 EAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVT 748
Query: 292 RTRKKESSCHSSVKEQ-KPLEKVFLKEDTGETHGDTRNDKIKPSTETRKLESVFFHSLSG 350
T+ + KE+ KPL++ KE G G K + +RK + + G
Sbjct: 749 ITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEG 808
Query: 351 SKSSRRNFKEQ 361
+ + KE+
Sbjct: 809 KEEVEQETKEK 819
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.124 0.331
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,228,953
Number of Sequences: 37866
Number of extensions: 684796
Number of successful extensions: 3862
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 378
Number of HSP's that attempted gapping in prelim test: 3284
Number of HSP's gapped (non-prelim): 767
length of query: 429
length of database: 18,247,518
effective HSP length: 105
effective length of query: 324
effective length of database: 14,271,588
effective search space: 4623994512
effective search space used: 4623994512
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.