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Search of human proteins with 186928819
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|186928819 hepatoma-derived growth factor isoform b [Homo
sapiens]
(256 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|186928819 hepatoma-derived growth factor isoform b [Homo sapi... 521 e-148
gi|186928821 hepatoma-derived growth factor isoform c [Homo sapi... 437 e-123
gi|4758516 hepatoma-derived growth factor isoform a [Homo sapiens] 432 e-121
gi|110681712 hepatoma derived growth factor-like 1 [Homo sapiens] 213 2e-55
gi|7705320 hepatoma-derived growth factor, related protein 3 [Ho... 158 5e-39
gi|190014588 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo... 145 4e-35
gi|190014586 PC4 and SFRS1 interacting protein 1 isoform 1 [Homo... 145 4e-35
gi|19923653 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo ... 145 4e-35
gi|48255931 hepatoma-derived growth factor-related protein 2 iso... 129 3e-30
gi|14249158 hepatoma-derived growth factor-related protein 2 iso... 129 3e-30
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 63 2e-10
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 51 9e-07
gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 49 6e-06
gi|40556376 cytokine-like nuclear factor n-pac [Homo sapiens] 49 6e-06
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 48 1e-05
gi|156104891 general transcription factor IIF, polypeptide 1, 74... 47 1e-05
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 47 2e-05
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 47 2e-05
gi|15721939 metastatic lymph node 51 [Homo sapiens] 47 2e-05
gi|157738619 smoothelin-like 1 [Homo sapiens] 46 4e-05
gi|21237808 SWI/SNF-related matrix-associated actin-dependent re... 45 5e-05
gi|21237805 SWI/SNF-related matrix-associated actin-dependent re... 45 5e-05
gi|194363725 SWI/SNF-related matrix-associated actin-dependent r... 45 5e-05
gi|4502805 chromogranin A precursor [Homo sapiens] 45 6e-05
gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapi... 45 8e-05
gi|5453994 RAD21 homolog [Homo sapiens] 44 1e-04
gi|118421089 chromodomain helicase DNA binding protein 2 isoform... 44 1e-04
gi|110611184 chromodomain helicase DNA binding protein 2 isoform... 44 1e-04
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 44 1e-04
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 44 1e-04
>gi|186928819 hepatoma-derived growth factor isoform b [Homo
sapiens]
Length = 256
Score = 521 bits (1342), Expect = e-148
Identities = 256/256 (100%), Positives = 256/256 (100%)
Query: 1 MHPEGGQFVPQLLGHLLATKLKRFLLSKGGRRAQIPDVSRATPHTIDEMPEAAVKSTANK 60
MHPEGGQFVPQLLGHLLATKLKRFLLSKGGRRAQIPDVSRATPHTIDEMPEAAVKSTANK
Sbjct: 1 MHPEGGQFVPQLLGHLLATKLKRFLLSKGGRRAQIPDVSRATPHTIDEMPEAAVKSTANK 60
Query: 61 YQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQ 120
YQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQ
Sbjct: 61 YQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQ 120
Query: 121 KKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLED 180
KKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLED
Sbjct: 121 KKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLED 180
Query: 181 SPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEA 240
SPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEA
Sbjct: 181 SPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEA 240
Query: 241 TKEDAEAPGIRDHESL 256
TKEDAEAPGIRDHESL
Sbjct: 241 TKEDAEAPGIRDHESL 256
>gi|186928821 hepatoma-derived growth factor isoform c [Homo
sapiens]
Length = 233
Score = 437 bits (1124), Expect = e-123
Identities = 216/228 (94%), Positives = 218/228 (95%)
Query: 29 GGRRAQIPDVSRATPHTIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEK 88
GG R Q ++ A IDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEK
Sbjct: 6 GGNRVQTSTLNCAGAAVIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEK 65
Query: 89 FGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGS 148
FGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGS
Sbjct: 66 FGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGS 125
Query: 149 SDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLP 208
SDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLP
Sbjct: 126 SDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLP 185
Query: 209 MEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIRDHESL 256
MEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIRDHESL
Sbjct: 186 MEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIRDHESL 233
>gi|4758516 hepatoma-derived growth factor isoform a [Homo sapiens]
Length = 240
Score = 432 bits (1111), Expect = e-121
Identities = 212/214 (99%), Positives = 212/214 (99%)
Query: 43 PHTIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGL 102
P IDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGL
Sbjct: 27 PARIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGL 86
Query: 103 WEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAK 162
WEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAK
Sbjct: 87 WEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAK 146
Query: 163 EKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGS 222
EKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGS
Sbjct: 147 EKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGS 206
Query: 223 GRGPPQEEEEEEDEEEEATKEDAEAPGIRDHESL 256
GRGPPQEEEEEEDEEEEATKEDAEAPGIRDHESL
Sbjct: 207 GRGPPQEEEEEEDEEEEATKEDAEAPGIRDHESL 240
>gi|110681712 hepatoma derived growth factor-like 1 [Homo sapiens]
Length = 251
Score = 213 bits (541), Expect = 2e-55
Identities = 122/218 (55%), Positives = 139/218 (63%), Gaps = 22/218 (10%)
Query: 59 NKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQS 118
N+YQVFFFGTHETAFL PK LFPY+E KEKFGKPNKR+GFS GLWEIENNPTV+AS
Sbjct: 36 NRYQVFFFGTHETAFLSPKRLFPYKECKEKFGKPNKRRGFSAGLWEIENNPTVQASDCPL 95
Query: 119 SQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLL 178
+ +K + P PEPEAAEGD DK +A G DE GK D+P +E EKG LKR AGD
Sbjct: 96 ASEKGSGDGPWPEPEAAEGDEDKPTHAGGGGDELGKPDDDKPTEE--EKGPLKRSAGDPP 153
Query: 179 EDSPKRPKEAENPEGEEKE---------------AATLEVERPLPMEVEKNSTPSEPGSG 223
ED+PKRPKEA + EE E A ++ E P + VE S PSEPG
Sbjct: 154 EDAPKRPKEAAPDQEEEAEAERAAEAERAAAAAAATAVDEESPFLVAVENGSAPSEPGLV 213
Query: 224 RGPPQEEEEEEDEEEEATKE-----DAEAPGIRDHESL 256
PPQ EEEE EEE A +E AEAPG D +SL
Sbjct: 214 CEPPQPEEEELREEEVADEEASQEWHAEAPGGGDRDSL 251
>gi|7705320 hepatoma-derived growth factor, related protein 3 [Homo
sapiens]
Length = 203
Score = 158 bits (399), Expect = 5e-39
Identities = 90/200 (45%), Positives = 117/200 (58%), Gaps = 23/200 (11%)
Query: 43 PHTIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGL 102
P IDE+PE AVK ANKY +FFFGTHETAFLGPKDLFPY+E K+KFGK NKRKGF+EGL
Sbjct: 26 PARIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGL 85
Query: 103 WEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEG-KLVIDEPA 161
WEIENNP VK +GYQ+ Q++S ++E +G+ A+ SS+EEG ++ D
Sbjct: 86 WEIENNPGVKFTGYQAIQQQS----------SSETEGEGGNTADASSEEEGDRVEEDGKG 135
Query: 162 KEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPG 221
K KNEK KR+ S K K++ G+E + E E+N + SE G
Sbjct: 136 KRKNEKAGSKRKKS---YTSKKSSKQSRKSPGDEDDKDCKE---------EENKSSSEGG 183
Query: 222 SGRGPPQEEEEEEDEEEEAT 241
+ + + E T
Sbjct: 184 DAGNDTRNTTSDLQKTSEGT 203
>gi|190014588 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo
sapiens]
Length = 530
Score = 145 bits (365), Expect = 4e-35
Identities = 96/246 (39%), Positives = 134/246 (54%), Gaps = 41/246 (16%)
Query: 43 PHTIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGL 102
P +DE+P+ AVK NK +FFFGTHETAFLGPKD+FPY E+KEK+GKPNKRKGF+EGL
Sbjct: 22 PARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFPYSENKEKYGKPNKRKGFNEGL 81
Query: 103 WEIENNPTVKASGYQSSQKK----SCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVID 158
WEI+NNP VK S Q++ K+ S VE E E ++ D D + E +S+E+ +D
Sbjct: 82 WEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTD---HEEKASNEDVTKAVD 138
Query: 159 --------EPAKEKNEKGALKRRAGDL--------LEDSPKRPKEA------ENPEGEEK 196
K K EK AG + L+ SPKR + A P G K
Sbjct: 139 ITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPK 198
Query: 197 EAATLEVERPLPME----VEKNSTPSEPGSGRGP---PQEEEEEEDEEEEATKEDAEAPG 249
V++P P E E++ + + + P P+++EE + EE++ KE + G
Sbjct: 199 -----MVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEG 253
Query: 250 IRDHES 255
++ ES
Sbjct: 254 KKEVES 259
Score = 32.0 bits (71), Expect = 0.54
Identities = 26/116 (22%), Positives = 51/116 (43%), Gaps = 10/116 (8%)
Query: 83 EESKEKFGKPNKRKGFSEGLWEIEN-NPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDK 141
EE +++ KP K EG E+E+ + +G S+ + E E + EG+ +
Sbjct: 235 EEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTST------SDSEEEGDDQEGEKKR 288
Query: 142 KGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKE 197
KG + ++ + KE ++ KR+ + +E + E + PE ++ E
Sbjct: 289 KGGRNFQTAHRRNMLKGQHEKEAADR---KRKQEEQMETEQQNKDEGKKPEVKKVE 341
>gi|190014586 PC4 and SFRS1 interacting protein 1 isoform 1 [Homo
sapiens]
Length = 333
Score = 145 bits (365), Expect = 4e-35
Identities = 96/246 (39%), Positives = 134/246 (54%), Gaps = 41/246 (16%)
Query: 43 PHTIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGL 102
P +DE+P+ AVK NK +FFFGTHETAFLGPKD+FPY E+KEK+GKPNKRKGF+EGL
Sbjct: 22 PARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFPYSENKEKYGKPNKRKGFNEGL 81
Query: 103 WEIENNPTVKASGYQSSQKK----SCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVID 158
WEI+NNP VK S Q++ K+ S VE E E ++ D D + E +S+E+ +D
Sbjct: 82 WEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTD---HEEKASNEDVTKAVD 138
Query: 159 --------EPAKEKNEKGALKRRAGDL--------LEDSPKRPKEA------ENPEGEEK 196
K K EK AG + L+ SPKR + A P G K
Sbjct: 139 ITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPK 198
Query: 197 EAATLEVERPLPME----VEKNSTPSEPGSGRGP---PQEEEEEEDEEEEATKEDAEAPG 249
V++P P E E++ + + + P P+++EE + EE++ KE + G
Sbjct: 199 -----MVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEG 253
Query: 250 IRDHES 255
++ ES
Sbjct: 254 KKEVES 259
>gi|19923653 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo
sapiens]
Length = 530
Score = 145 bits (365), Expect = 4e-35
Identities = 96/246 (39%), Positives = 134/246 (54%), Gaps = 41/246 (16%)
Query: 43 PHTIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGL 102
P +DE+P+ AVK NK +FFFGTHETAFLGPKD+FPY E+KEK+GKPNKRKGF+EGL
Sbjct: 22 PARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFPYSENKEKYGKPNKRKGFNEGL 81
Query: 103 WEIENNPTVKASGYQSSQKK----SCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVID 158
WEI+NNP VK S Q++ K+ S VE E E ++ D D + E +S+E+ +D
Sbjct: 82 WEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTD---HEEKASNEDVTKAVD 138
Query: 159 --------EPAKEKNEKGALKRRAGDL--------LEDSPKRPKEA------ENPEGEEK 196
K K EK AG + L+ SPKR + A P G K
Sbjct: 139 ITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPK 198
Query: 197 EAATLEVERPLPME----VEKNSTPSEPGSGRGP---PQEEEEEEDEEEEATKEDAEAPG 249
V++P P E E++ + + + P P+++EE + EE++ KE + G
Sbjct: 199 -----MVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEG 253
Query: 250 IRDHES 255
++ ES
Sbjct: 254 KKEVES 259
Score = 32.0 bits (71), Expect = 0.54
Identities = 26/116 (22%), Positives = 51/116 (43%), Gaps = 10/116 (8%)
Query: 83 EESKEKFGKPNKRKGFSEGLWEIEN-NPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDK 141
EE +++ KP K EG E+E+ + +G S+ + E E + EG+ +
Sbjct: 235 EEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTST------SDSEEEGDDQEGEKKR 288
Query: 142 KGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKE 197
KG + ++ + KE ++ KR+ + +E + E + PE ++ E
Sbjct: 289 KGGRNFQTAHRRNMLKGQHEKEAADR---KRKQEEQMETEQQNKDEGKKPEVKKVE 341
>gi|48255931 hepatoma-derived growth factor-related protein 2
isoform 1 [Homo sapiens]
Length = 671
Score = 129 bits (323), Expect = 3e-30
Identities = 74/197 (37%), Positives = 106/197 (53%), Gaps = 16/197 (8%)
Query: 43 PHTIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGL 102
P ID++ + AVK NKY +FFFGTHETAFLGPKDLFPY++ K+K+GKPNKRKGF+EGL
Sbjct: 22 PARIDDIADGAVKPPPNKYPIFFFGTHETAFLGPKDLFPYDKCKDKYGKPNKRKGFNEGL 81
Query: 103 WEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEG-DGDKKGNAEG--------SSDEEG 153
WEI+NNP + Y + S + PE A+G D D+ G ++
Sbjct: 82 WEIQNNP---HASYSAPPPVSSSDSEAPEANPADGSDADEDDEDRGVMAVTAVTATAASD 138
Query: 154 KLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEK 213
++ D + + ++ LKR+ L KR ++A + + + + E E EK
Sbjct: 139 RMESDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLDQASVSPSEEENSESSSESEK 198
Query: 214 NS----TPSEPGSGRGP 226
S TP + + R P
Sbjct: 199 TSDQDFTPEKKAAVRAP 215
Score = 38.1 bits (87), Expect = 0.008
Identities = 34/140 (24%), Positives = 56/140 (40%), Gaps = 13/140 (9%)
Query: 112 KASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALK 171
KA S K+ + +PEP A ++ SSD + + ++ EK K
Sbjct: 227 KAPSASDSDSKADSDGAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPK 286
Query: 172 RRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEE 231
R ++PK P ++ + EV+R + + E + R QEEE
Sbjct: 287 PRG--------RKPKPERPPSSSSSDSDSDEVDRISEWKRRDEARRRELEARRRREQEEE 338
Query: 232 -----EEEDEEEEATKEDAE 246
E+E EE+E +E A+
Sbjct: 339 LRRLREQEKEEKERRRERAD 358
Score = 35.4 bits (80), Expect = 0.049
Identities = 31/126 (24%), Positives = 51/126 (40%), Gaps = 6/126 (4%)
Query: 127 EPEPEPEAAEGDGDKKGN---AEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPK 183
+PE P ++ D D +E +E + E + + ++ L+R E+ +
Sbjct: 293 KPERPPSSSSSDSDSDEVDRISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKER 352
Query: 184 RPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEE-EDEEEEATK 242
R + A+ E E + E L + E G GRGPP + E E E E K
Sbjct: 353 RRERADRGEAERGSGGSSGDE--LREDDEPVKKRGRKGRGRGPPSSSDSEPEAELEREAK 410
Query: 243 EDAEAP 248
+ A+ P
Sbjct: 411 KSAKKP 416
Score = 35.0 bits (79), Expect = 0.064
Identities = 38/141 (26%), Positives = 60/141 (42%), Gaps = 27/141 (19%)
Query: 126 EEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKG---------------AL 170
EE E E A+ ++G+ S DE + DEP K++ KG L
Sbjct: 348 EEKERRRERADRGEAERGSGGSSGDELRE--DDEPVKKRGRKGRGRGPPSSSDSEPEAEL 405
Query: 171 KRRAGDLLEDSPKRPKE-----AENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRG 225
+R A + S K+P+ A P +EK E ++ P++VE+ SE G
Sbjct: 406 EREA----KKSAKKPQSSSTEPARKPGQKEKRVRPEEKQQAKPVKVERTRKRSE-GFSMD 460
Query: 226 PPQEEEEEEDEEEEATKEDAE 246
E+++E EE+ K +E
Sbjct: 461 RKVEKKKEPSVEEKLQKLHSE 481
Score = 32.0 bits (71), Expect = 0.54
Identities = 24/98 (24%), Positives = 38/98 (38%), Gaps = 16/98 (16%)
Query: 159 EPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPS 218
E ++ N+ G K +A + L +EA + E+K + L S
Sbjct: 556 EAVQKVNKAGMEKEKAEEKLAGEELAGEEAPQEKAEDKPSTDL----------------S 599
Query: 219 EPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIRDHESL 256
P +G Q+ E ED+E E ++ E P E L
Sbjct: 600 APVNGEATSQKGESAEDKEHEEGRDSEEGPRCGSSEDL 637
>gi|14249158 hepatoma-derived growth factor-related protein 2
isoform 2 [Homo sapiens]
Length = 670
Score = 129 bits (323), Expect = 3e-30
Identities = 74/197 (37%), Positives = 106/197 (53%), Gaps = 16/197 (8%)
Query: 43 PHTIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGL 102
P ID++ + AVK NKY +FFFGTHETAFLGPKDLFPY++ K+K+GKPNKRKGF+EGL
Sbjct: 22 PARIDDIADGAVKPPPNKYPIFFFGTHETAFLGPKDLFPYDKCKDKYGKPNKRKGFNEGL 81
Query: 103 WEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEG-DGDKKGNAEG--------SSDEEG 153
WEI+NNP + Y + S + PE A+G D D+ G ++
Sbjct: 82 WEIQNNP---HASYSAPPPVSSSDSEAPEANPADGSDADEDDEDRGVMAVTAVTATAASD 138
Query: 154 KLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEK 213
++ D + + ++ LKR+ L KR ++A + + + + E E EK
Sbjct: 139 RMESDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLDQASVSPSEEENSESSSESEK 198
Query: 214 NS----TPSEPGSGRGP 226
S TP + + R P
Sbjct: 199 TSDQDFTPEKKAAVRAP 215
Score = 38.1 bits (87), Expect = 0.008
Identities = 34/140 (24%), Positives = 56/140 (40%), Gaps = 13/140 (9%)
Query: 112 KASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALK 171
KA S K+ + +PEP A ++ SSD + + ++ EK K
Sbjct: 227 KAPSASDSDSKADSDGAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPK 286
Query: 172 RRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEE 231
R ++PK P ++ + EV+R + + E + R QEEE
Sbjct: 287 PRG--------RKPKPERPPSSSSSDSDSDEVDRISEWKRRDEARRRELEARRRREQEEE 338
Query: 232 -----EEEDEEEEATKEDAE 246
E+E EE+E +E A+
Sbjct: 339 LRRLREQEKEEKERRRERAD 358
Score = 35.4 bits (80), Expect = 0.049
Identities = 31/126 (24%), Positives = 51/126 (40%), Gaps = 6/126 (4%)
Query: 127 EPEPEPEAAEGDGDKKGN---AEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPK 183
+PE P ++ D D +E +E + E + + ++ L+R E+ +
Sbjct: 293 KPERPPSSSSSDSDSDEVDRISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKER 352
Query: 184 RPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEE-EDEEEEATK 242
R + A+ E E + E L + E G GRGPP + E E E E K
Sbjct: 353 RRERADRGEAERGSGGSSGDE--LREDDEPVKKRGRKGRGRGPPSSSDSEPEAELEREAK 410
Query: 243 EDAEAP 248
+ A+ P
Sbjct: 411 KSAKKP 416
Score = 35.0 bits (79), Expect = 0.064
Identities = 38/141 (26%), Positives = 60/141 (42%), Gaps = 27/141 (19%)
Query: 126 EEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKG---------------AL 170
EE E E A+ ++G+ S DE + DEP K++ KG L
Sbjct: 348 EEKERRRERADRGEAERGSGGSSGDELRE--DDEPVKKRGRKGRGRGPPSSSDSEPEAEL 405
Query: 171 KRRAGDLLEDSPKRPKE-----AENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRG 225
+R A + S K+P+ A P +EK E ++ P++VE+ SE G
Sbjct: 406 EREA----KKSAKKPQSSSTEPARKPGQKEKRVRPEEKQQAKPVKVERTRKRSE-GFSMD 460
Query: 226 PPQEEEEEEDEEEEATKEDAE 246
E+++E EE+ K +E
Sbjct: 461 RKVEKKKEPSVEEKLQKLHSE 481
Score = 32.0 bits (71), Expect = 0.54
Identities = 24/98 (24%), Positives = 38/98 (38%), Gaps = 16/98 (16%)
Query: 159 EPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPS 218
E ++ N+ G K +A + L +EA + E+K + L S
Sbjct: 556 EAVQKVNKAGMEKEKAEEKLAGEELAGEEAPQEKAEDKPSTDL----------------S 599
Query: 219 EPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIRDHESL 256
P +G Q+ E ED+E E ++ E P E L
Sbjct: 600 APVNGEATSQKGESAEDKEHEEGRDSEEGPRCGSSEDL 637
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 63.2 bits (152), Expect = 2e-10
Identities = 55/176 (31%), Positives = 81/176 (46%), Gaps = 19/176 (10%)
Query: 75 GPKDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEA 134
G K+L EE K++ G+ ++K +G + E N ++ G EE E E
Sbjct: 692 GEKELAEKEEWKKRDGEEQEQKEREQG-HQKERNQEMEEGG----------EEEHGEGEE 740
Query: 135 AEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGE 194
EGD +++ EG EEG+ E + + EK +R+ + K +E + EGE
Sbjct: 741 EEGDREEEEEKEGEGKEEGE---GEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGE 797
Query: 195 EKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEE-EDEEEEATKEDAEAPG 249
E+E E+ EVE E G+G +EEEEE E EEEE E+ E G
Sbjct: 798 EEETEGRGEEKEEGGEVE----GGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEG 849
Score = 56.6 bits (135), Expect = 2e-08
Identities = 52/173 (30%), Positives = 78/173 (45%), Gaps = 15/173 (8%)
Query: 83 EESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKK 142
EE +E G+ +G EG E G +++ E E E E EG+G+++
Sbjct: 860 EEGEEGEGEEEGEEGEGEGEEE---------EGEGEGEEEG---EGEGEEEEGEGEGEEE 907
Query: 143 GNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLE 202
G EG +EEG+ +E +E +G + G+ + + +E EGEE+E E
Sbjct: 908 GEGEGE-EEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEG-E 965
Query: 203 VERPLPMEVEKNSTPSEPGSGRGPPQEEE-EEEDEEEEATKEDAEAPGIRDHE 254
E E E+ E G G +EEE EEE EEE +E+ E G + E
Sbjct: 966 GEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEE 1018
Score = 49.3 bits (116), Expect = 3e-06
Identities = 45/166 (27%), Positives = 71/166 (42%), Gaps = 11/166 (6%)
Query: 84 ESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKG 143
E +E GK + EG E E G +++ E E E E EG+G+++G
Sbjct: 913 EEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEE--GEWEGEEEEGEGEGEEEG 970
Query: 144 NAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEV 203
EG EEG + +E+ +G + G+ E+ + + E EGE +E EV
Sbjct: 971 EGEG---EEG----EGEGEEEEGEGEGEEEEGE--EEGEEEGEGEEEGEGEGEEEEEGEV 1021
Query: 204 ERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPG 249
E + E + E G G +E+E E +E +E+ E G
Sbjct: 1022 EGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEG 1067
Score = 48.5 bits (114), Expect = 6e-06
Identities = 52/171 (30%), Positives = 75/171 (43%), Gaps = 15/171 (8%)
Query: 83 EESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKK 142
EE + G+ + +G E E E V+ + + + EE E E E EG+G+++
Sbjct: 789 EEGDQGEGEEEETEGRGE---EKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEE 845
Query: 143 GNAEGSSDE-EGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATL 201
EG +E EGK + E E+G G+ E + +E E EGEE+E
Sbjct: 846 -EGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEG-EGEEEEGEG- 902
Query: 202 EVERPLPMEVEKNSTPSEPGSGRGPPQEEE---EEEDEEEEATKEDAEAPG 249
E E E + E G G+G + EE E E+EE E ED E G
Sbjct: 903 EGE-----EEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEG 948
Score = 47.0 bits (110), Expect = 2e-05
Identities = 55/191 (28%), Positives = 79/191 (41%), Gaps = 31/191 (16%)
Query: 83 EESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGD-- 140
EE +E G+ + +G EG E E G + + EE E E E EG+G
Sbjct: 869 EEGEEGEGEGEEEEGEGEGEEEGEGE------GEEEEGEGEGEEEGEGEGEEEEGEGKGE 922
Query: 141 ---KKGNAEGSSDE---EGKLVIDEPAKEKNE-KGALKRRAGDLLEDSPKRPKEAENPEG 193
++G EG +E EG+ E +E+ E +G + G+ E+ +E E EG
Sbjct: 923 EEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEG-EG 981
Query: 194 EEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEE--------------EEDE-EE 238
EE+E E E E+ E G G G +EE E EE+E EE
Sbjct: 982 EEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEE 1041
Query: 239 EATKEDAEAPG 249
E + + E G
Sbjct: 1042 EGEEREKEGEG 1052
Score = 45.1 bits (105), Expect = 6e-05
Identities = 49/174 (28%), Positives = 73/174 (41%), Gaps = 19/174 (10%)
Query: 83 EESKEKFG-KPNKRKGFSEGLWEIE-NNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGD 140
E +EK G + +K G E E+E N VK G + + + ++ + E +EG
Sbjct: 585 EIPEEKEGAEDSKGNGIEEQ--EVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAK 642
Query: 141 KKGNAEGSSD-------EEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEG 193
G AE + EEG + E+ EKG + G++ + AE E
Sbjct: 643 SVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEW 702
Query: 194 EEKEAATLEV-ERPLPMEVEKNSTPSEPGS---GRGPPQEEEEEEDEEEEATKE 243
++++ E ER + E+N E G G G EEEE D EEE KE
Sbjct: 703 KKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEG----EEEEGDREEEEEKE 752
Score = 45.1 bits (105), Expect = 6e-05
Identities = 46/166 (27%), Positives = 71/166 (42%), Gaps = 23/166 (13%)
Query: 83 EESKEKFGKPNKRKGFSE-GLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDK 141
EE E G+ + +G E G WE E + G + + + E E E E EG+G++
Sbjct: 934 EEEGEGEGEDGEGEGEEEEGEWEGEEEEG-EGEGEEEGEGEGEEGEGEGEEEEGEGEGEE 992
Query: 142 K-GNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAAT 200
+ G EG + EG+ E E+ E+G ++ + + E E EGEE
Sbjct: 993 EEGEEEGEEEGEGE-EEGEGEGEEEEEGEVEGEV-----EGEEGEGEGEEEEGEE----- 1041
Query: 201 LEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAE 246
E E+ E R +EEEEEE + +E +E+ E
Sbjct: 1042 ---------EGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENE 1078
Score = 42.7 bits (99), Expect = 3e-04
Identities = 46/163 (28%), Positives = 69/163 (42%), Gaps = 19/163 (11%)
Query: 91 KPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSD 150
K +G ++ + E E+ P + G + ++ S E + E +G+ DK G E
Sbjct: 633 KAEVSEGKAKSVGEAEDGPEGRGDG--TCEEGSSGAEHWQDEEREKGEKDK-GRGEMERP 689
Query: 151 EEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRP--KEAENPE----GEEKEAATLEVE 204
EG+ KE EK K+R G+ E + ++ N E GEE+ E E
Sbjct: 690 GEGE-------KELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEE 742
Query: 205 RPLPMEVEKNSTPSEPGSG---RGPPQEEEEEEDEEEEATKED 244
E EK E G G G ++EE E +EE A KE+
Sbjct: 743 GDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEE 785
Score = 36.6 bits (83), Expect = 0.022
Identities = 36/133 (27%), Positives = 60/133 (45%), Gaps = 6/133 (4%)
Query: 83 EESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKK 142
E E+ G+ +G EG E E + G + ++ EE E E E EG+G+++
Sbjct: 963 EGEGEEEGEGEGEEGEGEG--EEEEG---EGEGEEEEGEEEGEEEGEGEEEG-EGEGEEE 1016
Query: 143 GNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLE 202
E + EG+ E +E+ E+ +R E++ + +E E EG+ +E E
Sbjct: 1017 EEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEE 1076
Query: 203 VERPLPMEVEKNS 215
ER E +K S
Sbjct: 1077 NERQDGEEYKKVS 1089
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 51.2 bits (121), Expect = 9e-07
Identities = 49/179 (27%), Positives = 83/179 (46%), Gaps = 15/179 (8%)
Query: 84 ESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGD--- 140
+S EK P K + S E +P VK + KS V+E PE A+
Sbjct: 703 KSPEKAKSPVKEEAKSP---EKAKSP-VKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKT 758
Query: 141 ---KKGNAEGSSDEEGKLVIDE-PAKEKN---EKGALKRRAGDLLEDSPKRPKEAENPEG 193
K A+ + EE + D+ P K K+ E+ +A L++ K P E E P+
Sbjct: 759 LDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAP-EKEIPKK 817
Query: 194 EEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIRD 252
EE ++ E E+P ++V++ +E P+ EE+++ ++EEA K++A P + +
Sbjct: 818 EEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEE 876
Score = 49.7 bits (117), Expect = 3e-06
Identities = 44/188 (23%), Positives = 82/188 (43%), Gaps = 22/188 (11%)
Query: 83 EESKEKFGKPNK--RKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDG- 139
+E+KE+ GK + + +EG E +P + + + KS V+E P A+
Sbjct: 476 KEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEK 535
Query: 140 -DKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKR-------------RAGDLLEDSPKRP 185
+ K AE S E+ K E AK E + ++ +A ++ K P
Sbjct: 536 EEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSP 595
Query: 186 KEAENPEG-----EEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEA 240
EA++PE +E+ + E + P+ E + + P + P +EE + ++ +
Sbjct: 596 AEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSP 655
Query: 241 TKEDAEAP 248
KE+A++P
Sbjct: 656 EKEEAKSP 663
Score = 48.5 bits (114), Expect = 6e-06
Identities = 39/138 (28%), Positives = 62/138 (44%), Gaps = 7/138 (5%)
Query: 117 QSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGD 176
+S +K VE+ E E E ++ E ++EE K +E KE+ E G + G
Sbjct: 439 KSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEE-EGGEEEEAEGG 497
Query: 177 LLEDSPKRPKEAENPEGEEKEAATLEVERPLPM---EVEKNSTPSE---PGSGRGPPQEE 230
E +EA +PE E K E + P E E+ +P+E P + P +EE
Sbjct: 498 EEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEE 557
Query: 231 EEEEDEEEEATKEDAEAP 248
+ E + KE+A++P
Sbjct: 558 AKSPPEAKSPEKEEAKSP 575
Score = 46.2 bits (108), Expect = 3e-05
Identities = 40/135 (29%), Positives = 64/135 (47%), Gaps = 20/135 (14%)
Query: 126 EEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAK-EKNEKGALKRRAGDLLEDSPKR 184
E+ E E E +G ++ AEG +E +E A EK K +K A K
Sbjct: 475 EKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEA--------KS 526
Query: 185 PKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQ----EEEEEEDEEEEA 240
P EA++PE EE ++ EV+ P EK +P++ + PP+ E+EE + E
Sbjct: 527 PAEAKSPEKEEAKSPA-EVKSP-----EKAKSPAKE-EAKSPPEAKSPEKEEAKSPAEVK 579
Query: 241 TKEDAEAPGIRDHES 255
+ E A++P + +S
Sbjct: 580 SPEKAKSPAKEEAKS 594
Score = 45.8 bits (107), Expect = 4e-05
Identities = 48/200 (24%), Positives = 78/200 (39%), Gaps = 36/200 (18%)
Query: 83 EESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKK 142
EE+K + K S E ++ P K+ + + KS E PE + + K
Sbjct: 536 EEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSP--EKEEAKSPAEVKSPEKAKSPAKEEAK 593
Query: 143 GNAEGSSDEEGKLVIDEPAKEKNE-KGALKRRAGDLLE------------DSPKRPKEAE 189
AE S E+ K + E AK E K +K A E + K P++A+
Sbjct: 594 SPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAK 653
Query: 190 NPEGEE-----KEAATLEVERPLPMEV-----------EKNSTP-----SEPGSGRGPPQ 228
+PE EE K + ++ E P + EK +P P + P +
Sbjct: 654 SPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVK 713
Query: 229 EEEEEEDEEEEATKEDAEAP 248
EE + ++ + KE+A+ P
Sbjct: 714 EEAKSPEKAKSPVKEEAKTP 733
Score = 40.8 bits (94), Expect = 0.001
Identities = 41/176 (23%), Positives = 72/176 (40%), Gaps = 18/176 (10%)
Query: 84 ESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKG 143
+S EK P K + S E KA + KS E P E A+ + K
Sbjct: 579 KSPEKAKSPAKEEAKSPA----EAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKS 634
Query: 144 NAEGSSDEEGKLVIDEPAKE-KNEKGALKRRAGDLLEDSPKRPKEAENP-----EGEEKE 197
+ S + + E AK + E+ +A ++ K P++A++P + EK
Sbjct: 635 PEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKA 694
Query: 198 AATLEVERPLPMEVEKNSTP-----SEPGSGRGPPQEEEEEEDEEEEATKEDAEAP 248
+ ++ E P EK +P P + P +EE + ++ + KE+A++P
Sbjct: 695 KSPVKEEAKSP---EKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSP 747
Score = 39.3 bits (90), Expect = 0.003
Identities = 48/212 (22%), Positives = 81/212 (38%), Gaps = 47/212 (22%)
Query: 84 ESKEKFGKPNKRKGFS--EGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDK 141
+S EK P K + S E ++ A + KS +E PE A+ +
Sbjct: 599 KSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKE 658
Query: 142 KG------------------------NAEGSSDEEGKLVIDEPAKEK-------NEKGAL 170
+ AE S E+ K + E AK E+
Sbjct: 659 EAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKS 718
Query: 171 KRRAGDLLEDSPKRPKEAENPEGEE----------KEAATLEVERP---LPMEVEKNSTP 217
+A +++ K P++A++P EE ++A TL+V+ P P + E S
Sbjct: 719 PEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPA 778
Query: 218 SE-PGSGRGPPQEEEEEEDEEEEATKEDAEAP 248
+ P + P +EE + ++ + KEDA+AP
Sbjct: 779 DKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAP 810
Score = 37.4 bits (85), Expect = 0.013
Identities = 38/177 (21%), Positives = 73/177 (41%), Gaps = 20/177 (11%)
Query: 86 KEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQK---------KSCVEEPEPEPEAAE 136
KE+ P K K + +P K + ++ KS V+E PE A+
Sbjct: 741 KEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAK 800
Query: 137 GDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALK-----RRAGDLLEDSPKRPKEAENP 191
+ A + K + P KE+ + +K ++A + E +P PK E
Sbjct: 801 SPLKEDAKAP-EKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEE--EKAPATPKTEEKK 857
Query: 192 EGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAP 248
+ +++EA E +P +VE+ P+ + ++EE +++++ + EAP
Sbjct: 858 DSKKEEAPKKEAPKP---KVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAP 911
Score = 34.3 bits (77), Expect = 0.11
Identities = 31/142 (21%), Positives = 65/142 (45%), Gaps = 13/142 (9%)
Query: 117 QSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGD 176
++ +KK +E P+ EA + ++K +E K+ + K E+ K++
Sbjct: 852 KTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKV------EAKKEEAEDKKKVPT 905
Query: 177 LLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGR--GPPQEEEEEE 234
+++P + + E+ + +EK EV + P + K PS+P + P +++ +EE
Sbjct: 906 PEKEAPAKVEVKEDAKPKEK----TEVAKKEPDDA-KAKEPSKPAEKKEAAPEKKDTKEE 960
Query: 235 DEEEEATKEDAEAPGIRDHESL 256
++ K EA D ++L
Sbjct: 961 KAKKPEEKPKTEAKAKEDDKTL 982
Score = 28.9 bits (63), Expect = 4.6
Identities = 17/76 (22%), Positives = 31/76 (40%)
Query: 119 SQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLL 178
++KK E + E ++K E + E+ K + EP+K K EK
Sbjct: 945 AEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKD 1004
Query: 179 EDSPKRPKEAENPEGE 194
P++ E + +G+
Sbjct: 1005 SKPPEKATEDKAAKGK 1020
Score = 28.5 bits (62), Expect = 6.0
Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 7/77 (9%)
Query: 179 EDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEE 238
E + + KEA+ EG+E+E E E E E S P+E + E+E + +
Sbjct: 469 EVTEEEEKEAKEEEGKEEEGG--EEEEAEGGEEETKSPPAEEAAS-----PEKEAKSPVK 521
Query: 239 EATKEDAEAPGIRDHES 255
E K AEA E+
Sbjct: 522 EEAKSPAEAKSPEKEEA 538
>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
Length = 282
Score = 48.5 bits (114), Expect = 6e-06
Identities = 38/144 (26%), Positives = 62/144 (43%), Gaps = 20/144 (13%)
Query: 117 QSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEK------------ 164
+ QK+ ++ E + EA + D D+KG +G D+ G E AKEK
Sbjct: 127 EEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGN-EKGEDAKEKEDGKKGEDGKGN 185
Query: 165 ----NEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEP 220
EKG ++ D E + E +G++KE ++V+ E E+ +
Sbjct: 186 GEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKED---EKEREDGKEDE 242
Query: 221 GSGRGPPQEEEEEEDEEEEATKED 244
G +E+E+ EEEE +ED
Sbjct: 243 GGNEEEAGKEKEDLKEEEEGKEED 266
Score = 34.7 bits (78), Expect = 0.083
Identities = 36/149 (24%), Positives = 61/149 (40%), Gaps = 29/149 (19%)
Query: 109 PTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKG 168
P VK SS+K + + + E + D A + +E V++E E + G
Sbjct: 32 PEVKPKRTSSSRKM------KTKSDMMEENIDTSAQAVAETKQEA--VVEEDYNENAKNG 83
Query: 169 ALKRRAG-----DLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSG 223
K +++E + ++A GE+KEA EV KN +
Sbjct: 84 EAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEV---------KNEEEDQ---- 130
Query: 224 RGPPQEEEEEEDEEEEATKEDAEAPGIRD 252
++EE++ +E+ EA KED + G D
Sbjct: 131 ---KEDEEDQNEEKGEAGKEDKDEKGEED 156
Score = 33.1 bits (74), Expect = 0.24
Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 3/84 (3%)
Query: 83 EESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKK 142
E+ KEK G+ K + + + + N K G + K V+E E E E +G D+
Sbjct: 187 EDGKEK-GEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKERE--DGKEDEG 243
Query: 143 GNAEGSSDEEGKLVIDEPAKEKNE 166
GN E + E+ L +E KE++E
Sbjct: 244 GNEEEAGKEKEDLKEEEEGKEEDE 267
Score = 32.7 bits (73), Expect = 0.32
Identities = 39/161 (24%), Positives = 66/161 (40%), Gaps = 16/161 (9%)
Query: 104 EIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGN--AEGSSDEEGKLVIDEPA 161
E N K + +S+K+ + E +A E G+KK AE ++EE + E
Sbjct: 78 ENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQ---KEDE 134
Query: 162 KEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPG 221
+++NE+ K AG +D E+ G EK E E E K +
Sbjct: 135 EDQNEE---KGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKE 191
Query: 222 SGRGPPQEEE--------EEEDEEEEATKEDAEAPGIRDHE 254
G +EE+ E ED +E+ K++ + +++ E
Sbjct: 192 KGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDE 232
Score = 30.8 bits (68), Expect = 1.2
Identities = 23/90 (25%), Positives = 38/90 (42%), Gaps = 4/90 (4%)
Query: 112 KASGYQSSQKKSCVEEPEPEPEAAEG----DGDKKGNAEGSSDEEGKLVIDEPAKEKNEK 167
K +G +K +E E E +G DG +KG+ + D + K E K ++
Sbjct: 183 KGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDE 242
Query: 168 GALKRRAGDLLEDSPKRPKEAENPEGEEKE 197
G + AG ED + + E E +E +
Sbjct: 243 GGNEEEAGKEKEDLKEEEEGKEEDEIKEDD 272
>gi|40556376 cytokine-like nuclear factor n-pac [Homo sapiens]
Length = 553
Score = 48.5 bits (114), Expect = 6e-06
Identities = 56/199 (28%), Positives = 82/199 (41%), Gaps = 21/199 (10%)
Query: 43 PHTIDEMPEAAVKSTANK-YQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEG 101
P I P+ K K + V FFGT + A++ + L PY KE+ K NK K F +
Sbjct: 23 PGKIVNPPKDLKKPRGKKCFFVKFFGTEDHAWIKVEQLKPYHAHKEEMIKINKGKRFQQA 82
Query: 102 LWEIEN-----NPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKK-GNAEGSSDE---E 152
+ +E + S + SS K+ E GD +K +EG + E
Sbjct: 83 VDAVEEFLRRAKGKDQTSSHNSSDDKNRRNSSEERSRPNSGDEKRKLSLSEGKVKKNMGE 142
Query: 153 GKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEE----KEAATLEVERPLP 208
GK + + E+ K LKR E SP+ K P+ E+ E++T++ P
Sbjct: 143 GKKRVSSGSSERGSKSPLKRAQ----EQSPR--KRGRPPKDEKDLTIPESSTVKGMMAGP 196
Query: 209 MEVEK-NSTPSEPGSGRGP 226
M K T SEP P
Sbjct: 197 MAAFKWQPTASEPVKDADP 215
>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 1 [Homo sapiens]
Length = 1099
Score = 47.8 bits (112), Expect = 1e-05
Identities = 35/131 (26%), Positives = 61/131 (46%), Gaps = 3/131 (2%)
Query: 119 SQKKSCVEEPEPEPEAA-EGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDL 177
++ +S E P E E A EG+ ++K E + EG+ +E ++ + + +
Sbjct: 748 AEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNE 807
Query: 178 LEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGR--GPPQEEEEEED 235
ED + E +G E E + E+ E + + E G G G +EEEEEE+
Sbjct: 808 GEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEE 867
Query: 236 EEEEATKEDAE 246
E+EE +E+ +
Sbjct: 868 EQEEEEEEEEQ 878
Score = 47.0 bits (110), Expect = 2e-05
Identities = 50/183 (27%), Positives = 75/183 (40%), Gaps = 27/183 (14%)
Query: 75 GPKDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEA 134
G +D+ E + E G+ + G EG E ++ + G ++ + EE E E EA
Sbjct: 743 GQEDVAEAESTGEMPGEEGETAG--EGETEEKSGGETQPEGEGETETQGKGEECEDENEA 800
Query: 135 AEGDGDKKGNAEGSSD-EEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEG 193
EG GD +G EG E+G++ +E E E A E + ++ +
Sbjct: 801 -EGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDS 859
Query: 194 EEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIRDH 253
EE+E E E +EEEEEE EEEE +E+ E G +
Sbjct: 860 EEEEEEEEEQE-----------------------EEEEEEEQEEEEEEEEEEEEKGNEEP 896
Query: 254 ESL 256
SL
Sbjct: 897 LSL 899
>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
[Homo sapiens]
Length = 517
Score = 47.4 bits (111), Expect = 1e-05
Identities = 44/163 (26%), Positives = 77/163 (47%), Gaps = 20/163 (12%)
Query: 83 EESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSS-QKKSCVEEPEPEPEAAEGDGDK 141
EE KEK G+ RK + ++E++ + + +S ++ V + + + A+G G K
Sbjct: 191 EEEKEKRGR---RKASELRIHDLEDDLEMSSDASDASGEEGGRVPKAKKKAPLAKG-GRK 246
Query: 142 KGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATL 201
K +GS DE A E ++ G + + D + D +E E E K A
Sbjct: 247 KKKKKGSDDE---------AFEDSDDGDFEGQEVDYMSDGSSSSQE----EPESKAKAPQ 293
Query: 202 EVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKED 244
+ E P V++ S SE PP+E++EEE+E++ T ++
Sbjct: 294 QEEGP--KGVDEQSDSSEESEEEKPPEEDKEEEEEKKAPTPQE 334
Score = 38.9 bits (89), Expect = 0.004
Identities = 39/150 (26%), Positives = 64/150 (42%), Gaps = 12/150 (8%)
Query: 91 KPNKRKGFSEGLWEIENNPTVKAS--GYQSSQKKSCVEEPEPEPEAAEGDGDKKG---NA 145
K K+KG + +E ++ + Y S S EEPE + +A + + KG +
Sbjct: 246 KKKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQS 305
Query: 146 EGSSDEEGKLVIDEPAKEKNEKGA----LKRRAGDLLEDSPKRPKEAENPEGEEKEAATL 201
+ S + E + +E +E+ EK A K+R D E+S E + + E A +
Sbjct: 306 DSSEESEEEKPPEEDKEEEEEKKAPTPQEKKRRKDSSEESDS--SEESDIDSEASSALFM 363
Query: 202 EVERPLPMEVEKNSTPSEPGSGR-GPPQEE 230
++ P K S S G+ R G P E
Sbjct: 364 AKKKTPPKRERKPSGGSSRGNSRPGTPSAE 393
Score = 37.7 bits (86), Expect = 0.010
Identities = 32/130 (24%), Positives = 55/130 (42%), Gaps = 18/130 (13%)
Query: 115 GYQSSQKKSCVEEPEPEPEAAEGDG---DKKGNAEGSSDEEGKLVIDEPAKEKNEKGALK 171
G + +KK +E + + + +G D + SS EE + P +E+ KG +
Sbjct: 244 GRKKKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKG-VD 302
Query: 172 RRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEE 231
++ E ++P E + E EEK+A P P E ++ SE +
Sbjct: 303 EQSDSSEESEEEKPPEEDKEEEEEKKA-------PTPQEKKRRKDSSE-------ESDSS 348
Query: 232 EEEDEEEEAT 241
EE D + EA+
Sbjct: 349 EESDIDSEAS 358
Score = 37.4 bits (85), Expect = 0.013
Identities = 40/175 (22%), Positives = 68/175 (38%), Gaps = 21/175 (12%)
Query: 83 EESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKK 142
EE++E++ + NK + + + + +K+ + E E D +
Sbjct: 158 EEAEEEWERRNKVLNHFSIMQQRRLKDQDQDEDEEEKEKRGRRKASELRIHDLEDDLEMS 217
Query: 143 GNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLE 202
+A +S EEG V K KG K+ K+ K +++ E+ + E
Sbjct: 218 SDASDASGEEGGRVPKAKKKAPLAKGGRKK----------KKKKGSDDEAFEDSDDGDFE 267
Query: 203 VERPLPMEVEKNSTPSEPGSGRGPPQEEE-----------EEEDEEEEATKEDAE 246
+ M +S+ EP S PQ+EE EE EEE+ +ED E
Sbjct: 268 GQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKE 322
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 47.0 bits (110), Expect = 2e-05
Identities = 47/183 (25%), Positives = 78/183 (42%), Gaps = 19/183 (10%)
Query: 77 KDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAE 136
K Y+ + + + NKR +I + + Y++ +K+CV + +PE A
Sbjct: 90 KSATEYKNEEYQRSERNKRLDADR---KIRLSSSASREPYKNQPEKTCVRKRDPERRA-- 144
Query: 137 GDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLED-----SPKRPKEAENP 191
K +GS E L +D A ++ + + + D S ++ N
Sbjct: 145 ----KSPTPDGS--ERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNT 198
Query: 192 EGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIR 251
E EE E +VE EVE+++ E G +EEEEEE+EEEE +E+ R
Sbjct: 199 ENEE-EGVEEDVEED--EEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDER 255
Query: 252 DHE 254
D +
Sbjct: 256 DQK 258
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 47.0 bits (110), Expect = 2e-05
Identities = 47/183 (25%), Positives = 78/183 (42%), Gaps = 19/183 (10%)
Query: 77 KDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAE 136
K Y+ + + + NKR +I + + Y++ +K+CV + +PE A
Sbjct: 90 KSATEYKNEEYQRSERNKRLDADR---KIRLSSSASREPYKNQPEKTCVRKRDPERRA-- 144
Query: 137 GDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLED-----SPKRPKEAENP 191
K +GS E L +D A ++ + + + D S ++ N
Sbjct: 145 ----KSPTPDGS--ERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNT 198
Query: 192 EGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIR 251
E EE E +VE EVE+++ E G +EEEEEE+EEEE +E+ R
Sbjct: 199 ENEE-EGVEEDVEED--EEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDER 255
Query: 252 DHE 254
D +
Sbjct: 256 DQK 258
>gi|15721939 metastatic lymph node 51 [Homo sapiens]
Length = 703
Score = 46.6 bits (109), Expect = 2e-05
Identities = 37/130 (28%), Positives = 65/130 (50%), Gaps = 13/130 (10%)
Query: 111 VKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGAL 170
V++ G +S+++ C E E +A D + +AE S EEG E ++E+N K L
Sbjct: 64 VESGGAKSAEESECESEDGIEGDAVLSDYE---SAEDSEGEEG-----EYSEEENSKVEL 115
Query: 171 KRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEE 230
K A D + S K K E P+ + +T+ ER + ++++ P E G+ P+
Sbjct: 116 KSEANDAVNSSTKEEKGEEKPDTK----STVTGERQ-SGDGQESTEPVENKVGKKGPKHL 170
Query: 231 EEEEDEEEEA 240
+++ED + A
Sbjct: 171 DDDEDRKNPA 180
>gi|157738619 smoothelin-like 1 [Homo sapiens]
Length = 512
Score = 45.8 bits (107), Expect = 4e-05
Identities = 48/200 (24%), Positives = 86/200 (43%), Gaps = 24/200 (12%)
Query: 46 IDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGLWEI 105
++ EA K A G E +G +++ +E E +P + + L
Sbjct: 96 VESQREAGGKEDAEAELKKEDGEKEETTVGSQEMTGRKE--ETKSEPKEAEEKESTLASE 153
Query: 106 ENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKK-------GNAEGSSDEEGKLVID 158
+ K + +S QK + +PEP+A + D K G + S E + D
Sbjct: 154 KQKAEEKEAKPESGQKADANDRDKPEPKATVEEEDAKTASQEETGQRKECSTEPKEKATD 213
Query: 159 EPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPS 218
E AK +++K ++ +++ PKE P+G+E+ + E E E ++ +
Sbjct: 214 EEAKAESQKAVVE-------DEAKAEPKE---PDGKEEAKHGAKEEADAKEEAE-DAEEA 262
Query: 219 EPGSGRGPPQEEEEEEDEEE 238
EPGS P EE+E++ E+E
Sbjct: 263 EPGS----PSEEQEQDVEKE 278
Score = 40.4 bits (93), Expect = 0.002
Identities = 47/207 (22%), Positives = 78/207 (37%), Gaps = 29/207 (14%)
Query: 76 PKDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAA 135
P + E++ + G + +G + GL E++ +A G + ++ + E+ E E E
Sbjct: 65 PTESGKQEKAPAEDGMSAELQGEANGLDEVKVESQREAGGKEDAEAELKKEDGEKE-ETT 123
Query: 136 EGDGDKKGNAEGSSDE-------EGKLVIDEPAKEKNE---KGALKRRAGDLLEDSPKRP 185
G + G E + E E L ++ E+ E + K A D + PK
Sbjct: 124 VGSQEMTGRKEETKSEPKEAEEKESTLASEKQKAEEKEAKPESGQKADANDRDKPEPKAT 183
Query: 186 KEAENPE-------GEEKEAATLEVERPLPMEV-----------EKNSTPSEPGSGRGPP 227
E E+ + G+ KE +T E+ E E + P EP
Sbjct: 184 VEEEDAKTASQEETGQRKECSTEPKEKATDEEAKAESQKAVVEDEAKAEPKEPDGKEEAK 243
Query: 228 QEEEEEEDEEEEATKEDAEAPGIRDHE 254
+EE D +EEA + PG E
Sbjct: 244 HGAKEEADAKEEAEDAEEAEPGSPSEE 270
Score = 35.4 bits (80), Expect = 0.049
Identities = 34/155 (21%), Positives = 63/155 (40%), Gaps = 10/155 (6%)
Query: 104 EIENNPTVKASGYQS---SQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEP 160
E P KA+ ++ SQK +E + EP+ +G + K A+ +D + + E
Sbjct: 202 ECSTEPKEKATDEEAKAESQKAVVEDEAKAEPKEPDGKEEAKHGAKEEADAKEEAEDAEE 261
Query: 161 AK-----EKNEKGALKRRAGD--LLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEK 213
A+ E+ E+ K G ++ SP+ E+ EG L + +
Sbjct: 262 AEPGSPSEEQEQDVEKEPEGGAGVIPSSPEEWPESPTGEGHNLSTDGLGPDCVASGQTSP 321
Query: 214 NSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAP 248
+++ S P P E +++E+A + AP
Sbjct: 322 SASESSPSDVPQSPPESPSSGEKKEKAPERRVSAP 356
>gi|21237808 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin c2 isoform b [Homo sapiens]
Length = 1130
Score = 45.4 bits (106), Expect = 5e-05
Identities = 34/121 (28%), Positives = 59/121 (48%), Gaps = 22/121 (18%)
Query: 131 EPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAEN 190
EPE E G+ + EG + +E K EP + + GA++ A + ++PK+ +E
Sbjct: 778 EPERIEESGNDEARVEGQATDEKK----EPKEPREGGGAIEEEAKEKTSEAPKKDEE--- 830
Query: 191 PEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGI 250
+G+E ++ EK S S+ G P++E+E ++ +EE KE E+ G
Sbjct: 831 -KGKEGDS-------------EKESEKSD-GDPIVDPEKEKEPKEGQEEVLKEVVESEGE 875
Query: 251 R 251
R
Sbjct: 876 R 876
Score = 31.6 bits (70), Expect = 0.71
Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 11/76 (14%)
Query: 180 DSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEE 239
D P+R +E+ N E + AT ++ P EP G G +EE +E+ E
Sbjct: 777 DEPERIEESGNDEARVEGQAT-----------DEKKEPKEPREGGGAIEEEAKEKTSEAP 825
Query: 240 ATKEDAEAPGIRDHES 255
E+ G + ES
Sbjct: 826 KKDEEKGKEGDSEKES 841
Score = 30.0 bits (66), Expect = 2.1
Identities = 25/105 (23%), Positives = 42/105 (40%), Gaps = 15/105 (14%)
Query: 104 EIENNPTVKASGYQSSQKKS---------CVEEPEPEPEAAEGDGDKKGNAEGSSDEE-- 152
E N + G + +KK +EE E + D++ EG S++E
Sbjct: 783 EESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKESE 842
Query: 153 ---GKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGE 194
G ++D P KEK K + +++E +R + E GE
Sbjct: 843 KSDGDPIVD-PEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGE 886
>gi|21237805 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin c2 isoform a [Homo sapiens]
Length = 1214
Score = 45.4 bits (106), Expect = 5e-05
Identities = 34/121 (28%), Positives = 59/121 (48%), Gaps = 22/121 (18%)
Query: 131 EPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAEN 190
EPE E G+ + EG + +E K EP + + GA++ A + ++PK+ +E
Sbjct: 747 EPERIEESGNDEARVEGQATDEKK----EPKEPREGGGAIEEEAKEKTSEAPKKDEE--- 799
Query: 191 PEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGI 250
+G+E ++ EK S S+ G P++E+E ++ +EE KE E+ G
Sbjct: 800 -KGKEGDS-------------EKESEKSD-GDPIVDPEKEKEPKEGQEEVLKEVVESEGE 844
Query: 251 R 251
R
Sbjct: 845 R 845
Score = 31.6 bits (70), Expect = 0.71
Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 11/76 (14%)
Query: 180 DSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEE 239
D P+R +E+ N E + AT ++ P EP G G +EE +E+ E
Sbjct: 746 DEPERIEESGNDEARVEGQAT-----------DEKKEPKEPREGGGAIEEEAKEKTSEAP 794
Query: 240 ATKEDAEAPGIRDHES 255
E+ G + ES
Sbjct: 795 KKDEEKGKEGDSEKES 810
Score = 30.0 bits (66), Expect = 2.1
Identities = 25/105 (23%), Positives = 42/105 (40%), Gaps = 15/105 (14%)
Query: 104 EIENNPTVKASGYQSSQKKS---------CVEEPEPEPEAAEGDGDKKGNAEGSSDEE-- 152
E N + G + +KK +EE E + D++ EG S++E
Sbjct: 752 EESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKESE 811
Query: 153 ---GKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGE 194
G ++D P KEK K + +++E +R + E GE
Sbjct: 812 KSDGDPIVD-PEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGE 855
>gi|194363725 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin c2 isoform c [Homo sapiens]
Length = 1152
Score = 45.4 bits (106), Expect = 5e-05
Identities = 34/121 (28%), Positives = 59/121 (48%), Gaps = 22/121 (18%)
Query: 131 EPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAEN 190
EPE E G+ + EG + +E K EP + + GA++ A + ++PK+ +E
Sbjct: 778 EPERIEESGNDEARVEGQATDEKK----EPKEPREGGGAIEEEAKEKTSEAPKKDEE--- 830
Query: 191 PEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGI 250
+G+E ++ EK S S+ G P++E+E ++ +EE KE E+ G
Sbjct: 831 -KGKEGDS-------------EKESEKSD-GDPIVDPEKEKEPKEGQEEVLKEVVESEGE 875
Query: 251 R 251
R
Sbjct: 876 R 876
Score = 31.6 bits (70), Expect = 0.71
Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 11/76 (14%)
Query: 180 DSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEE 239
D P+R +E+ N E + AT ++ P EP G G +EE +E+ E
Sbjct: 777 DEPERIEESGNDEARVEGQAT-----------DEKKEPKEPREGGGAIEEEAKEKTSEAP 825
Query: 240 ATKEDAEAPGIRDHES 255
E+ G + ES
Sbjct: 826 KKDEEKGKEGDSEKES 841
Score = 30.0 bits (66), Expect = 2.1
Identities = 25/105 (23%), Positives = 42/105 (40%), Gaps = 15/105 (14%)
Query: 104 EIENNPTVKASGYQSSQKKS---------CVEEPEPEPEAAEGDGDKKGNAEGSSDEE-- 152
E N + G + +KK +EE E + D++ EG S++E
Sbjct: 783 EESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKESE 842
Query: 153 ---GKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGE 194
G ++D P KEK K + +++E +R + E GE
Sbjct: 843 KSDGDPIVD-PEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGE 886
>gi|4502805 chromogranin A precursor [Homo sapiens]
Length = 457
Score = 45.1 bits (105), Expect = 6e-05
Identities = 49/197 (24%), Positives = 75/197 (38%), Gaps = 48/197 (24%)
Query: 85 SKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGN 144
+KE+ + K GF + L E+ N + +A + K VEEP + + + K+
Sbjct: 87 AKERAHQQKKHSGFEDELSEVLENQSSQA------ELKEAVEEPSSKDVMEKREDSKEAE 140
Query: 145 AEGSSDEEGK-LVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEV 203
G + + + + EP +E +G +A E EE+E AT
Sbjct: 141 KSGEATDGARPQALPEPMQESKAEGN----------------NQAPGEEEEEEEEAT-NT 183
Query: 204 ERPLPMEVEKNSTPSEPGSGRGPPQ-------------------EEEEEEDEEEEATKE- 243
P + +K P G G Q EEEEEE+EE EA +E
Sbjct: 184 HPPASLPSQKYPGPQAEGDSEGLSQGLVDREKGLSAEPGWQAKREEEEEEEEEAEAGEEA 243
Query: 244 --DAEAPGI--RDHESL 256
+ E P + H SL
Sbjct: 244 VPEEEGPTVVLNPHPSL 260
>gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapiens]
Length = 1790
Score = 44.7 bits (104), Expect = 8e-05
Identities = 38/146 (26%), Positives = 60/146 (41%), Gaps = 27/146 (18%)
Query: 122 KSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDS 181
K +++ E E + + + S+EE + E +E++E ++
Sbjct: 1588 KLTLDQEEATESTVESEEESSSDYTEYSEEESEFSESETTEEESES------------ET 1635
Query: 182 PKRPKEAENPEGEEKEAATLEVE-----------RPLPMEV-EKNSTPSEPGSGRGPPQE 229
P +E+ PE EE E+ E E RP+ EV E EP + P+
Sbjct: 1636 PSEEEESSTPESEESESTESEGEKARKNIVLARRRPMVEEVKEVKGRKEEPQEEQKEPKM 1695
Query: 230 EEEEEDEEEE---ATKEDAEAPGIRD 252
EEEE EEEE A E++ P +D
Sbjct: 1696 EEEEHSEEEESGPAPVEESTDPEAQD 1721
Score = 32.7 bits (73), Expect = 0.32
Identities = 35/165 (21%), Positives = 64/165 (38%), Gaps = 7/165 (4%)
Query: 83 EESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKK 142
EE K+ ++ +E E E + + Y + + E E +E +++
Sbjct: 1581 EEDKDYLKLTLDQEEATESTVESEEESSSDYTEYSEEESEFSESETTEEESESETPSEEE 1640
Query: 143 GNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEK--EAAT 200
++ S+E + KN A +R + +++ R +E + + E K E
Sbjct: 1641 ESSTPESEESESTESEGEKARKNIVLARRRPMVEEVKEVKGRKEEPQEEQKEPKMEEEEH 1700
Query: 201 LEVERPLPMEVEKNSTPS-----EPGSGRGPPQEEEEEEDEEEEA 240
E E P VE+++ P E GS E E +EE E+
Sbjct: 1701 SEEEESGPAPVEESTDPEAQDIPEEGSAESASVEGGVESEEESES 1745
Score = 28.5 bits (62), Expect = 6.0
Identities = 24/106 (22%), Positives = 45/106 (42%), Gaps = 5/106 (4%)
Query: 147 GSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENP-EGEEKEAATLEVER 205
G +D+ G ++D +E + L+ D L+ + + + E+ E EE+ ++
Sbjct: 1560 GLADKRG--IVDLEGEEWQRR--LEEEDKDYLKLTLDQEEATESTVESEEESSSDYTEYS 1615
Query: 206 PLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIR 251
E ++ T E P +EEE E EE+ ++E R
Sbjct: 1616 EEESEFSESETTEEESESETPSEEEESSTPESEESESTESEGEKAR 1661
>gi|5453994 RAD21 homolog [Homo sapiens]
Length = 631
Score = 44.3 bits (103), Expect = 1e-04
Identities = 41/166 (24%), Positives = 66/166 (39%), Gaps = 18/166 (10%)
Query: 84 ESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKG 143
E K K + E L E EN + Q Q++ ++EP E +
Sbjct: 399 EDLRKRRKGGEADNLDEFLKEFENPEVPREDQQQQHQQRDVIDEPIIE---------EPS 449
Query: 144 NAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEV 203
+ S E + IDE A +KR+AG + + P++ E E E
Sbjct: 450 RLQESVMEASRTNIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVE------ 503
Query: 204 ERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPG 249
LP E N P P +E+E+E+++E++ +ED +A G
Sbjct: 504 ---LPPEEPPNICQLIPELELLPEKEKEKEKEKEDDEEEEDEDASG 546
>gi|118421089 chromodomain helicase DNA binding protein 2 isoform 1
[Homo sapiens]
Length = 1828
Score = 44.3 bits (103), Expect = 1e-04
Identities = 46/168 (27%), Positives = 71/168 (42%), Gaps = 31/168 (18%)
Query: 106 ENNPTVKASGYQS-SQKKSCVEEPEPE-PEAAEGDGDKKGN------------------- 144
E+N + ++S QS S+ +S + +P PEA E KK
Sbjct: 52 ESNSSSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRR 111
Query: 145 AEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPK---RPKEAENPEG----EEKE 197
+ S E + I E A +E G+ KRR L+ K P E E +G E E
Sbjct: 112 SNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPE 171
Query: 198 AATLEVERPLPME-VEKNSTPSEPGSGRG--PPQEEEEEEDEEEEATK 242
++ RP+P V K +P + RG Q+ +E+D+++EA K
Sbjct: 172 QKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPK 219
Score = 35.4 bits (80), Expect = 0.049
Identities = 32/117 (27%), Positives = 56/117 (47%), Gaps = 9/117 (7%)
Query: 140 DKKGNAEGSSDEEGKLVIDEP-AKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEA 198
+KKG G EE KL +P K++N+ LK G L P+ ++NP EE E
Sbjct: 1326 EKKGAVTGG--EEAKLKKRKPRVKKENKVPRLKEEHGIELSS----PRHSDNPS-EEGEV 1378
Query: 199 ATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIRDHES 255
+E+ PM+ ++ ++ + +++E D+E + +K+ E P D +S
Sbjct: 1379 KDDGLEKS-PMKKKQKKKENKENKEKQMSSRKDKEGDKERKKSKDKKEKPKSGDAKS 1434
Score = 28.5 bits (62), Expect = 6.0
Identities = 39/170 (22%), Positives = 66/170 (38%), Gaps = 20/170 (11%)
Query: 93 NKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEE 152
NK K E N + AS S E E + G G + ++ SS+ +
Sbjct: 4 NKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQ 63
Query: 153 GKLVIDEPAK-------EKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVER 205
+ + E EK A K+ + + D K +E + G + + +
Sbjct: 64 SESESESAGSKSQPVLPEAKEKPASKK---ERIADVKKMWEEYPDVYGVRRSNRSRQEPS 120
Query: 206 PLPMEVEKNSTPSEPGSG--RGPPQ-------EEEEEEDEEEEATKEDAE 246
++ E+ S+ SE GS RG Q ++E EDE+E+ T ++E
Sbjct: 121 RFNIK-EEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESE 169
>gi|110611184 chromodomain helicase DNA binding protein 2 isoform 2
[Homo sapiens]
Length = 501
Score = 44.3 bits (103), Expect = 1e-04
Identities = 46/168 (27%), Positives = 71/168 (42%), Gaps = 31/168 (18%)
Query: 106 ENNPTVKASGYQS-SQKKSCVEEPEPE-PEAAEGDGDKKGN------------------- 144
E+N + ++S QS S+ +S + +P PEA E KK
Sbjct: 52 ESNSSSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRR 111
Query: 145 AEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPK---RPKEAENPEG----EEKE 197
+ S E + I E A +E G+ KRR L+ K P E E +G E E
Sbjct: 112 SNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPE 171
Query: 198 AATLEVERPLPME-VEKNSTPSEPGSGRG--PPQEEEEEEDEEEEATK 242
++ RP+P V K +P + RG Q+ +E+D+++EA K
Sbjct: 172 QKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPK 219
Score = 28.5 bits (62), Expect = 6.0
Identities = 39/170 (22%), Positives = 66/170 (38%), Gaps = 20/170 (11%)
Query: 93 NKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEE 152
NK K E N + AS S E E + G G + ++ SS+ +
Sbjct: 4 NKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQ 63
Query: 153 GKLVIDEPAK-------EKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVER 205
+ + E EK A K+ + + D K +E + G + + +
Sbjct: 64 SESESESAGSKSQPVLPEAKEKPASKK---ERIADVKKMWEEYPDVYGVRRSNRSRQEPS 120
Query: 206 PLPMEVEKNSTPSEPGSG--RGPPQ-------EEEEEEDEEEEATKEDAE 246
++ E+ S+ SE GS RG Q ++E EDE+E+ T ++E
Sbjct: 121 RFNIK-EEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESE 169
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 43.9 bits (102), Expect = 1e-04
Identities = 38/181 (20%), Positives = 81/181 (44%), Gaps = 17/181 (9%)
Query: 83 EESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGD-- 140
EE K++ GK N+ E E +N ++ KK + DG+
Sbjct: 1259 EEGKKRTGKQNEENPGDE---EAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESG 1315
Query: 141 --KKGNAEGSSDEEGK---LVIDEPAKEKN-EKGALKRRAGDLLEDSPKRPKEAENPEGE 194
KK + + +G+ V E +++ + ++ + + ++ R + A+ E E
Sbjct: 1316 EEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELE 1375
Query: 195 EKEAATLEVERPLPMEVEKNSTPSEPGSG------RGPPQEEEEEEDEEEEATKEDAEAP 248
E + + + ++ ++V+++S+ + + +EEEEEE+EEEE +D+++P
Sbjct: 1376 ENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSP 1435
Query: 249 G 249
G
Sbjct: 1436 G 1436
Score = 42.4 bits (98), Expect = 4e-04
Identities = 42/167 (25%), Positives = 68/167 (40%), Gaps = 18/167 (10%)
Query: 83 EESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKK 142
E +EK KP + K E++ K S S S +E E +E + +++
Sbjct: 1313 ESGEEKKTKPKEHK-------EVKGRNRRKVSSEDSED--SDFQESGVSEEVSESEDEQR 1363
Query: 143 GNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLE 202
+ E ++E +++ K KRR + EDS K E EEKE E
Sbjct: 1364 PRTRSAKKAE----LEE--NQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEE 1417
Query: 203 VERPLPMEVEKNSTPSEPGSGRGPPQ---EEEEEEDEEEEATKEDAE 246
E E ++N PG GR + ++++ E + A KE+ E
Sbjct: 1418 EEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEE 1464
Score = 32.7 bits (73), Expect = 0.32
Identities = 35/133 (26%), Positives = 54/133 (40%), Gaps = 13/133 (9%)
Query: 111 VKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGAL 170
+K SS+ KS EE E E E E + +++ E +++ K G
Sbjct: 1390 IKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSK-----------SPGKG 1438
Query: 171 KRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEE 230
+++ +L+D R E +N EE+E ER E + E S P
Sbjct: 1439 RKKIRKILKDDKLRT-ETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITT 1497
Query: 231 EEEEDEEEEATKE 243
+ DE+EE TKE
Sbjct: 1498 KLVLDEDEE-TKE 1509
Score = 30.4 bits (67), Expect = 1.6
Identities = 36/165 (21%), Positives = 62/165 (37%), Gaps = 8/165 (4%)
Query: 83 EESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKK 142
EES E K +R + ++ K + ++S K+ + E D D+
Sbjct: 1121 EESSEDNKKKKQRTSSKKKAVIVKEK---KRNSLRTSTKRKQADITSSSSSDIEDD-DQN 1176
Query: 143 GNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAEN----PEGEEKEA 198
EGSSDE+ + E + G + + L S + ++ PE +
Sbjct: 1177 SIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKK 1236
Query: 199 ATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKE 243
LE + E S+ EP G+ ++ EE +EEA +
Sbjct: 1237 MLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQ 1281
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 43.9 bits (102), Expect = 1e-04
Identities = 38/181 (20%), Positives = 81/181 (44%), Gaps = 17/181 (9%)
Query: 83 EESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGD-- 140
EE K++ GK N+ E E +N ++ KK + DG+
Sbjct: 1297 EEGKKRTGKQNEENPGDE---EAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESG 1353
Query: 141 --KKGNAEGSSDEEGK---LVIDEPAKEKN-EKGALKRRAGDLLEDSPKRPKEAENPEGE 194
KK + + +G+ V E +++ + ++ + + ++ R + A+ E E
Sbjct: 1354 EEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELE 1413
Query: 195 EKEAATLEVERPLPMEVEKNSTPSEPGSG------RGPPQEEEEEEDEEEEATKEDAEAP 248
E + + + ++ ++V+++S+ + + +EEEEEE+EEEE +D+++P
Sbjct: 1414 ENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSP 1473
Query: 249 G 249
G
Sbjct: 1474 G 1474
Score = 42.4 bits (98), Expect = 4e-04
Identities = 42/167 (25%), Positives = 68/167 (40%), Gaps = 18/167 (10%)
Query: 83 EESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKK 142
E +EK KP + K E++ K S S S +E E +E + +++
Sbjct: 1351 ESGEEKKTKPKEHK-------EVKGRNRRKVSSEDSED--SDFQESGVSEEVSESEDEQR 1401
Query: 143 GNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLE 202
+ E ++E +++ K KRR + EDS K E EEKE E
Sbjct: 1402 PRTRSAKKAE----LEE--NQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEE 1455
Query: 203 VERPLPMEVEKNSTPSEPGSGRGPPQ---EEEEEEDEEEEATKEDAE 246
E E ++N PG GR + ++++ E + A KE+ E
Sbjct: 1456 EEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEE 1502
Score = 32.7 bits (73), Expect = 0.32
Identities = 35/133 (26%), Positives = 54/133 (40%), Gaps = 13/133 (9%)
Query: 111 VKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGAL 170
+K SS+ KS EE E E E E + +++ E +++ K G
Sbjct: 1428 IKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSK-----------SPGKG 1476
Query: 171 KRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEE 230
+++ +L+D R E +N EE+E ER E + E S P
Sbjct: 1477 RKKIRKILKDDKLRT-ETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITT 1535
Query: 231 EEEEDEEEEATKE 243
+ DE+EE TKE
Sbjct: 1536 KLVLDEDEE-TKE 1547
Score = 30.4 bits (67), Expect = 1.6
Identities = 36/165 (21%), Positives = 62/165 (37%), Gaps = 8/165 (4%)
Query: 83 EESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKK 142
EES E K +R + ++ K + ++S K+ + E D D+
Sbjct: 1159 EESSEDNKKKKQRTSSKKKAVIVKEK---KRNSLRTSTKRKQADITSSSSSDIEDD-DQN 1214
Query: 143 GNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAEN----PEGEEKEA 198
EGSSDE+ + E + G + + L S + ++ PE +
Sbjct: 1215 SIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKK 1274
Query: 199 ATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKE 243
LE + E S+ EP G+ ++ EE +EEA +
Sbjct: 1275 MLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQ 1319
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.303 0.128 0.358
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,808,332
Number of Sequences: 37866
Number of extensions: 749149
Number of successful extensions: 14167
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 472
Number of HSP's successfully gapped in prelim test: 650
Number of HSP's that attempted gapping in prelim test: 5999
Number of HSP's gapped (non-prelim): 4708
length of query: 256
length of database: 18,247,518
effective HSP length: 100
effective length of query: 156
effective length of database: 14,460,918
effective search space: 2255903208
effective search space used: 2255903208
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.