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Search of human proteins with 186910323
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|186910323 hypothetical protein LOC79969 isoform 2 [Homo
sapiens]
(333 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|186910323 hypothetical protein LOC79969 isoform 2 [Homo sapiens] 676 0.0
gi|13699803 WAS protein family, member 3 [Homo sapiens] 42 0.001
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 39 0.005
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 39 0.005
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 39 0.005
gi|113204604 aristaless-like homeobox 3 [Homo sapiens] 39 0.008
gi|239756083 PREDICTED: hypothetical protein [Homo sapiens] 39 0.008
gi|239750612 PREDICTED: hypothetical protein [Homo sapiens] 39 0.008
gi|239744919 PREDICTED: hypothetical protein XP_002343307 [Homo ... 39 0.008
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 39 0.008
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 38 0.011
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 38 0.011
gi|153792074 proline rich 12 [Homo sapiens] 38 0.011
gi|239753975 PREDICTED: hypothetical protein [Homo sapiens] 38 0.014
gi|46909600 a disintegrin and metalloproteinase domain 15 isofor... 38 0.014
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 38 0.014
gi|46909598 a disintegrin and metalloproteinase domain 15 isofor... 37 0.019
gi|55750053 atrophin-1 [Homo sapiens] 37 0.019
gi|55750041 atrophin-1 [Homo sapiens] 37 0.019
gi|55741675 hypothetical protein LOC22889 [Homo sapiens] 37 0.019
gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 37 0.019
gi|11386183 WAS protein family, member 2 [Homo sapiens] 37 0.025
gi|237757312 synaptojanin 1 isoform c [Homo sapiens] 36 0.042
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 36 0.055
gi|14149904 anthrax toxin receptor 1 isoform 1 precursor [Homo s... 36 0.055
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 36 0.055
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 36 0.055
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 36 0.055
gi|4759144 solute carrier family 9 (sodium/hydrogen exchanger), ... 35 0.072
gi|169169586 PREDICTED: hypothetical protein [Homo sapiens] 35 0.072
>gi|186910323 hypothetical protein LOC79969 isoform 2 [Homo sapiens]
Length = 333
Score = 676 bits (1745), Expect = 0.0
Identities = 333/333 (100%), Positives = 333/333 (100%)
Query: 1 MEFPFDVDALFPERITVLDQHLRPPARRPGTTTPARVDLQQQIMTIIDELGKASAKAQNL 60
MEFPFDVDALFPERITVLDQHLRPPARRPGTTTPARVDLQQQIMTIIDELGKASAKAQNL
Sbjct: 1 MEFPFDVDALFPERITVLDQHLRPPARRPGTTTPARVDLQQQIMTIIDELGKASAKAQNL 60
Query: 61 SAPITSASRMQSNRHVVYILKDSSARPAGKGAIIGFIKVGYKKLFVLDDREAHNEVEPLC 120
SAPITSASRMQSNRHVVYILKDSSARPAGKGAIIGFIKVGYKKLFVLDDREAHNEVEPLC
Sbjct: 61 SAPITSASRMQSNRHVVYILKDSSARPAGKGAIIGFIKVGYKKLFVLDDREAHNEVEPLC 120
Query: 121 ILDFYIHESVQRHGHGRELFQYMLQKERVEPHQLAIDRPSQKLLKFLNKHYNLETTVPQV 180
ILDFYIHESVQRHGHGRELFQYMLQKERVEPHQLAIDRPSQKLLKFLNKHYNLETTVPQV
Sbjct: 121 ILDFYIHESVQRHGHGRELFQYMLQKERVEPHQLAIDRPSQKLLKFLNKHYNLETTVPQV 180
Query: 181 NNFVIFEGFFAHQHRPPAPSLRATRHSRAAAVDPTPAAPARKLPPKRAEGDIKPYSSSDR 240
NNFVIFEGFFAHQHRPPAPSLRATRHSRAAAVDPTPAAPARKLPPKRAEGDIKPYSSSDR
Sbjct: 181 NNFVIFEGFFAHQHRPPAPSLRATRHSRAAAVDPTPAAPARKLPPKRAEGDIKPYSSSDR 240
Query: 241 EFLKVAVEPPWPLNRAPRRATPPAHPPPRSSSLGNSPERGPLRPFVPEQELLRSLRLCPP 300
EFLKVAVEPPWPLNRAPRRATPPAHPPPRSSSLGNSPERGPLRPFVPEQELLRSLRLCPP
Sbjct: 241 EFLKVAVEPPWPLNRAPRRATPPAHPPPRSSSLGNSPERGPLRPFVPEQELLRSLRLCPP 300
Query: 301 HPTARLLLAADPGGSPAQRRRTSSLPRSEESRY 333
HPTARLLLAADPGGSPAQRRRTSSLPRSEESRY
Sbjct: 301 HPTARLLLAADPGGSPAQRRRTSSLPRSEESRY 333
>gi|13699803 WAS protein family, member 3 [Homo sapiens]
Length = 502
Score = 41.6 bits (96), Expect = 0.001
Identities = 36/129 (27%), Positives = 54/129 (41%), Gaps = 15/129 (11%)
Query: 192 HQHRPPAPSLRATRHSRAAAVDPTPAAPARKLPPKRAEGD--IKPYSSSDREFLKVAVEP 249
H++RPP+ S R +R P P PP+ EG P + +D L +
Sbjct: 284 HEYRPPSASARHMALNRPQQPPPPP-------PPQAPEGSQASAPMAPADYGMLPAQIIE 336
Query: 250 PWPLNRAPRRATPPAHPPPRSSSLGNSPERGPLRPFVPEQELLRSLRLCPPHP--TARLL 307
+ + P PP P +++ + SP + P++P P S PPHP T L+
Sbjct: 337 YYNPSGPPPPPPPPVIPSAQTAFV--SPLQMPMQPPFPAS--ASSTHAAPPHPPSTGLLV 392
Query: 308 LAADPGGSP 316
A P G P
Sbjct: 393 TAPPPPGPP 401
Score = 34.7 bits (78), Expect = 0.12
Identities = 35/116 (30%), Positives = 39/116 (33%), Gaps = 13/116 (11%)
Query: 196 PPAPSLRATRHSRAAAVDPTPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPPWPLNR 255
PP P ++ A V P P + P L A PP P
Sbjct: 344 PPPPPPPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGP--- 400
Query: 256 APRRATPPAHPPPRSSSLGNSPERGPLRPFVPEQELLRSLRLCPPHPTARL-LLAA 310
PP PP SSL +SP GP P E R PP AR LLAA
Sbjct: 401 ----PPPPPGPPGPGSSLSSSPMHGP-----PVAEAKRQEPAQPPISDARSDLLAA 447
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 39.3 bits (90), Expect = 0.005
Identities = 40/122 (32%), Positives = 48/122 (39%), Gaps = 18/122 (14%)
Query: 196 PPAPSLRATRHSRAAAVD---PTPAAPARKLPPKRAEGDIKPYSS----SDREFLKVAVE 248
P PS R SRAA + P PA AR PP EG K SS S E A
Sbjct: 169 PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP--TEGPRKSVSSASEHSTTEPSPAARR 226
Query: 249 PPW-------PLNRAPRRATPPAHPPPRSSSLGNSPERGPLRPFVPEQELLRSLRLCPPH 301
P P +R+ + P P RS R P P P+ + L++LR PP
Sbjct: 227 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR--PPQ 284
Query: 302 PT 303
T
Sbjct: 285 VT 286
Score = 36.6 bits (83), Expect = 0.032
Identities = 43/151 (28%), Positives = 60/151 (39%), Gaps = 15/151 (9%)
Query: 173 LETTVPQVNNFVIFEGFFAHQHRPPAPSLRATRHSRAA------AVDPTPAAPARKLPPK 226
L T PQ N + A PP+P ++A A+ A P+ A P+ PP
Sbjct: 420 LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPL 479
Query: 227 R------AEGDIKPYSSSDREFLKVAVEPPWPLNRAPRRATPPAHPPPRSSSLGNSPERG 280
+ A + P ++ + PP L + P +A PPA P +L + P
Sbjct: 480 QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA-PPALATPPLQALPSPPASF 538
Query: 281 P-LRPFVPEQELLRSLRLCPPHPTARLLLAA 310
P PF P L S PP P A +LAA
Sbjct: 539 PGQAPFSPSASLPMSPLATPP-PQAPPVLAA 568
Score = 29.3 bits (64), Expect = 5.1
Identities = 36/127 (28%), Positives = 49/127 (38%), Gaps = 19/127 (14%)
Query: 198 APSLRATRHSRAAAVDPTPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPPWPLNRAP 257
AP+L S A P+ A ++ P A P+SSS L + P PL
Sbjct: 293 APALGPLSSSPLATPSPSAALQSQAPPTLPAT----PHSSS----LTCQLATPLPLAPPS 344
Query: 258 RRA--------TPPAHPPPRSSSLGNSPERGPLRPFVPEQELLRSLRLCPPHPTARLLLA 309
A +PPA PP ++++ SP F+P L L P P A LA
Sbjct: 345 PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPL---SPLATPPPQAPPALA 401
Query: 310 ADPGGSP 316
P +P
Sbjct: 402 LPPLQAP 408
Score = 29.3 bits (64), Expect = 5.1
Identities = 34/115 (29%), Positives = 42/115 (36%), Gaps = 13/115 (11%)
Query: 217 AAPARKLPPKRAEGDIKPYSSSDREFLKVA-VEPPWPLNRAPRRATPPAHPPPRSSSLGN 275
A P + PP A ++ S F A P L +P PP PP ++ L
Sbjct: 513 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 572
Query: 276 SPERGPLRPFVPEQELLRSLRLCP-PHPTA-----RLLLAADPGGSPAQRRRTSS 324
P P P L++ R P P P RL LA PG P R SS
Sbjct: 573 VP------PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS 621
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 39.3 bits (90), Expect = 0.005
Identities = 40/122 (32%), Positives = 48/122 (39%), Gaps = 18/122 (14%)
Query: 196 PPAPSLRATRHSRAAAVD---PTPAAPARKLPPKRAEGDIKPYSS----SDREFLKVAVE 248
P PS R SRAA + P PA AR PP EG K SS S E A
Sbjct: 169 PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP--TEGPRKSVSSASEHSTTEPSPAARR 226
Query: 249 PPW-------PLNRAPRRATPPAHPPPRSSSLGNSPERGPLRPFVPEQELLRSLRLCPPH 301
P P +R+ + P P RS R P P P+ + L++LR PP
Sbjct: 227 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR--PPQ 284
Query: 302 PT 303
T
Sbjct: 285 VT 286
Score = 34.3 bits (77), Expect = 0.16
Identities = 41/156 (26%), Positives = 53/156 (33%), Gaps = 21/156 (13%)
Query: 173 LETTVPQVNNFVIFEGFFAHQHRPPAPSLRATRHSRAAAVDPTPAAPARKLPPKRAEGDI 232
L T PQ N + A PP+P ++A A+ A P + PP A
Sbjct: 645 LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP- 703
Query: 233 KPYSSSDREFLKVAVEPPWPLNRAPRRATPPAHPPPRSSSLGNSPERGPLRPFVPEQELL 292
L+V PP +P PP PPP ++ P P P +
Sbjct: 704 ----------LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPS--- 750
Query: 293 RSLRLCPPHPTARLLLAADPGGSPAQRRRTSSLPRS 328
P P LLAA P P +SLP S
Sbjct: 751 -----ATPPPRVPPLLAAPPLQVPPS--PPASLPMS 779
Score = 31.6 bits (70), Expect = 1.0
Identities = 37/129 (28%), Positives = 49/129 (37%), Gaps = 15/129 (11%)
Query: 196 PPAPSLRATRHSRAAAVDPTPAAPARKLPPKR-AEGDIKPYSSSDREF--------LKVA 246
PPA + + P AAP ++PP A + P ++ L+V
Sbjct: 710 PPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVP 769
Query: 247 VEPPWPLNRAPRRATPPAHPP----PRSSSLGNSPERGP-LRPFVPEQELLRSLRLCPPH 301
PP L +P PP PP P +L + P P PF P L S PP
Sbjct: 770 PSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP- 828
Query: 302 PTARLLLAA 310
P A +LAA
Sbjct: 829 PQAPPVLAA 837
Score = 30.0 bits (66), Expect = 3.0
Identities = 38/134 (28%), Positives = 48/134 (35%), Gaps = 13/134 (9%)
Query: 198 APSLRATRHSRAAAVDPTPAAPARKLPPKRAEGDIKPYSSSDREFLKVA-VEPPWPLNRA 256
AP L+ A+ A P + PP A ++ S F A P L +
Sbjct: 763 APPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS 822
Query: 257 PRRATPPAHPPPRSSSLGNSPERGPLRPFVPEQELLRSLRLCP-PHPTA-----RLLLAA 310
P PP PP ++ L P P P L++ R P P P RL LA
Sbjct: 823 PLATPPPQAPPVLAAPLLQVP------PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLAL 876
Query: 311 DPGGSPAQRRRTSS 324
PG P R SS
Sbjct: 877 APGPPPPPSRSPSS 890
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 39.3 bits (90), Expect = 0.005
Identities = 40/122 (32%), Positives = 48/122 (39%), Gaps = 18/122 (14%)
Query: 196 PPAPSLRATRHSRAAAVD---PTPAAPARKLPPKRAEGDIKPYSS----SDREFLKVAVE 248
P PS R SRAA + P PA AR PP EG K SS S E A
Sbjct: 160 PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP--TEGPRKSVSSASEHSTTEPSPAARR 217
Query: 249 PPW-------PLNRAPRRATPPAHPPPRSSSLGNSPERGPLRPFVPEQELLRSLRLCPPH 301
P P +R+ + P P RS R P P P+ + L++LR PP
Sbjct: 218 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR--PPQ 275
Query: 302 PT 303
T
Sbjct: 276 VT 277
Score = 36.6 bits (83), Expect = 0.032
Identities = 43/151 (28%), Positives = 60/151 (39%), Gaps = 15/151 (9%)
Query: 173 LETTVPQVNNFVIFEGFFAHQHRPPAPSLRATRHSRAA------AVDPTPAAPARKLPPK 226
L T PQ N + A PP+P ++A A+ A P+ A P+ PP
Sbjct: 381 LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPL 440
Query: 227 R------AEGDIKPYSSSDREFLKVAVEPPWPLNRAPRRATPPAHPPPRSSSLGNSPERG 280
+ A + P ++ + PP L + P +A PPA P +L + P
Sbjct: 441 QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA-PPALATPPLQALPSPPASF 499
Query: 281 P-LRPFVPEQELLRSLRLCPPHPTARLLLAA 310
P PF P L S PP P A +LAA
Sbjct: 500 PGQAPFSPSASLPMSPLATPP-PQAPPVLAA 529
Score = 32.7 bits (73), Expect = 0.46
Identities = 37/128 (28%), Positives = 50/128 (39%), Gaps = 16/128 (12%)
Query: 199 PSLRATRHSRAAAVDPTPAA-----PARKLPPKR-AEGDIKPYSSSDREFLKVAVEP--- 249
PS R T + A P P P + PP++ A + P SSS + P
Sbjct: 248 PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPS 307
Query: 250 -PWPLNRAPRRATPPAHPPPRSSSLGNSPERGPLRPFVPEQELLRSLRLCPPHPTARLLL 308
P L P +PPA PP ++++ SP F+P L L P P A L
Sbjct: 308 APPSLQTLP---SPPATPPSQATTSLGSPTLQATHSFLPSPPL---SPLATPPPQAPPAL 361
Query: 309 AADPGGSP 316
A P +P
Sbjct: 362 ALPPLQAP 369
Score = 31.6 bits (70), Expect = 1.0
Identities = 40/154 (25%), Positives = 53/154 (34%), Gaps = 22/154 (14%)
Query: 195 RPPA--PSLRATRHSRAAAVDPTPAAPAR-------KLPPKRA-EGDIKPYSS------S 238
RPP P + S + +P+PAA R + P R+ P SS S
Sbjct: 190 RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPS 249
Query: 239 DREFLKVAVEPPWPLNRAPRRATPPAHPPPRSSS------LGNSPERGPLRPFVPEQELL 292
R + P P + + PP PPR + L +SP P P
Sbjct: 250 ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAP 309
Query: 293 RSLRLCPPHPTARLLLAADPGGSPAQRRRTSSLP 326
SL+ P P A GSP + S LP
Sbjct: 310 PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLP 343
Score = 29.3 bits (64), Expect = 5.1
Identities = 34/115 (29%), Positives = 42/115 (36%), Gaps = 13/115 (11%)
Query: 217 AAPARKLPPKRAEGDIKPYSSSDREFLKVA-VEPPWPLNRAPRRATPPAHPPPRSSSLGN 275
A P + PP A ++ S F A P L +P PP PP ++ L
Sbjct: 474 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 533
Query: 276 SPERGPLRPFVPEQELLRSLRLCP-PHPTA-----RLLLAADPGGSPAQRRRTSS 324
P P P L++ R P P P RL LA PG P R SS
Sbjct: 534 VP------PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS 582
>gi|113204604 aristaless-like homeobox 3 [Homo sapiens]
Length = 343
Score = 38.5 bits (88), Expect = 0.008
Identities = 36/103 (34%), Positives = 42/103 (40%), Gaps = 26/103 (25%)
Query: 212 VDPTPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPPWPLNRAPRRATPPAHP-PPRS 270
+DP AP R P A G PY +S E PP P + A P HP PPR
Sbjct: 1 MDPEHCAPFRVGP---APG---PYVASGDE-------PPGP--QGTPAAAPHLHPAPPRG 45
Query: 271 SSLGNSPERGPLRPFVPEQELLRSLRLCPPHPTARLLLAADPG 313
L P GPL P++PE P P A+ L PG
Sbjct: 46 PRLTRFPACGPLEPYLPE----------PAKPPAKYLQDLGPG 78
>gi|239756083 PREDICTED: hypothetical protein [Homo sapiens]
Length = 174
Score = 38.5 bits (88), Expect = 0.008
Identities = 33/87 (37%), Positives = 40/87 (45%), Gaps = 17/87 (19%)
Query: 243 LKVAVEPPWPLNRAPRRATPPAHPPPRSSSLGNSPERGPLRPFVPEQELLRSLRL----C 298
+ V PPWPL AP A+ P PP R + P P +LR LRL C
Sbjct: 2 IPVGSSPPWPL--AP--ASGPGRPPERKDLV------APPDPTAQSPRVLRGLRLLAHRC 51
Query: 299 PPHPTARLLLAADPG-GSPAQRRRTSS 324
PP A+LL A PG G P + R+ S
Sbjct: 52 PPSGEAKLL--ARPGTGRPRRSPRSRS 76
>gi|239750612 PREDICTED: hypothetical protein [Homo sapiens]
Length = 174
Score = 38.5 bits (88), Expect = 0.008
Identities = 33/87 (37%), Positives = 40/87 (45%), Gaps = 17/87 (19%)
Query: 243 LKVAVEPPWPLNRAPRRATPPAHPPPRSSSLGNSPERGPLRPFVPEQELLRSLRL----C 298
+ V PPWPL AP A+ P PP R + P P +LR LRL C
Sbjct: 2 IPVGSSPPWPL--AP--ASGPGRPPERKDLV------APPDPTAQSPRVLRGLRLLAHRC 51
Query: 299 PPHPTARLLLAADPG-GSPAQRRRTSS 324
PP A+LL A PG G P + R+ S
Sbjct: 52 PPSGEAKLL--ARPGTGRPRRSPRSRS 76
>gi|239744919 PREDICTED: hypothetical protein XP_002343307 [Homo
sapiens]
Length = 174
Score = 38.5 bits (88), Expect = 0.008
Identities = 33/87 (37%), Positives = 40/87 (45%), Gaps = 17/87 (19%)
Query: 243 LKVAVEPPWPLNRAPRRATPPAHPPPRSSSLGNSPERGPLRPFVPEQELLRSLRL----C 298
+ V PPWPL AP A+ P PP R + P P +LR LRL C
Sbjct: 2 IPVGSSPPWPL--AP--ASGPGRPPERKDLV------APPDPTAQSPRVLRGLRLLAHRC 51
Query: 299 PPHPTARLLLAADPG-GSPAQRRRTSS 324
PP A+LL A PG G P + R+ S
Sbjct: 52 PPSGEAKLL--ARPGTGRPRRSPRSRS 76
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 38.5 bits (88), Expect = 0.008
Identities = 36/120 (30%), Positives = 46/120 (38%), Gaps = 12/120 (10%)
Query: 199 PSLRATRHSRAAAVDPTPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPPWPLNRAPR 258
PSL A + AA P + PA PP + P S F V P P+ P
Sbjct: 667 PSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMS----FAPVLPPPSTPMPTGPG 722
Query: 259 RATPPAHPPPRSSSLGNSPERGPLRPFVPEQELLRSLRLCPPHPTARLLLAADPGGSPAQ 318
+ PP PP + P+ +P VP Q + PPH L A G+PAQ
Sbjct: 723 QPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPV-------PPH-LPPYLAPASQVGAPAQ 774
Score = 32.3 bits (72), Expect = 0.61
Identities = 29/102 (28%), Positives = 38/102 (37%), Gaps = 10/102 (9%)
Query: 206 HSRAAAVDPTPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPPWPL-----NRAPRRA 260
HS A + P PA P+ A D+ P S + PP P P+
Sbjct: 900 HSAVAQLPGQPVYPAAF--PQMAPTDVPP--SPHHTVQNMRATPPQPALPPQPTLPPQPV 955
Query: 261 TPPAHPPPRSSSLGNSPERGPLRPFVPEQELLRSLRLCPPHP 302
PP P L P R P +P +P Q +L + PP P
Sbjct: 956 LPPQPTLPPQPVLPPQPTRPP-QPVLPPQPMLPPQPVLPPQP 996
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 38.1 bits (87), Expect = 0.011
Identities = 33/114 (28%), Positives = 47/114 (41%), Gaps = 19/114 (16%)
Query: 196 PPAPSLRATRHSRAAAVDPTPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPPW---P 252
PP L + A+ + P P PP+ E + P + R F PP+ P
Sbjct: 556 PPPEELPTSPPPEASRLSPPPEESPMSPPPE--ESPMSPPPEASRLF------PPFEESP 607
Query: 253 LNRAPRRATPPAHPPPRSSSLGNSPERGPLRPFVPEQELLRSLRLCPPHPTARL 306
L+ P + P PPP +S L PE P+ P PE+ + PP +RL
Sbjct: 608 LSPPPEES--PLSPPPEASRLSPPPEDSPMSP-PPEES-----PMSPPPEVSRL 653
Score = 34.7 bits (78), Expect = 0.12
Identities = 27/84 (32%), Positives = 30/84 (35%), Gaps = 1/84 (1%)
Query: 249 PPWPLNRAPRRATPPAHPPPRSSSLGNSPERGPLRPFVPEQELLRSLRLCP-PHPTARLL 307
PP +P P PPP +S L PE P P L R L P P
Sbjct: 443 PPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESP 502
Query: 308 LAADPGGSPAQRRRTSSLPRSEES 331
L+ P SP S L EES
Sbjct: 503 LSPPPESSPFSPLEESPLSPPEES 526
Score = 33.9 bits (76), Expect = 0.21
Identities = 34/111 (30%), Positives = 47/111 (42%), Gaps = 13/111 (11%)
Query: 196 PPAPSLRATRHSRAAAVDPTPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPPWPLNR 255
P +P A SR ++ +P +P PP+ + P SS + + PP
Sbjct: 475 PASPLPEALHLSRP--LEESPLSP----PPEESPLSPPPESSPFSPLEESPLSPPEESPP 528
Query: 256 APRRATPPAHPPPRSSSLGNSPERGPLRPFVPEQELLRSLRLCPPHPTARL 306
+P TP PPP +S L E PL P P +EL S PP +RL
Sbjct: 529 SPALETP-LSPPPEASPLSPPFEESPLSP--PPEELPTS----PPPEASRL 572
Score = 33.1 bits (74), Expect = 0.36
Identities = 32/115 (27%), Positives = 41/115 (35%), Gaps = 14/115 (12%)
Query: 214 PTPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPPWPLNRAPRRATPPAHPPPRSSSL 273
P+PA PP A P+ S PP L +P PPP S +
Sbjct: 528 PSPALETPLSPPPEASPLSPPFEESPLS------PPPEELPTSPPPEASRLSPPPEESPM 581
Query: 274 GNSPERGPLRPFVPEQELLRSLRLCPPHPTARLLLAAD--PGGSPAQRRRTSSLP 326
PE P+ P PE + RL PP + L + P P + R S P
Sbjct: 582 SPPPEESPMSP-PPE-----ASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPP 630
Score = 31.6 bits (70), Expect = 1.0
Identities = 37/139 (26%), Positives = 52/139 (37%), Gaps = 21/139 (15%)
Query: 196 PPAPSLRATRHSRAAAVDPTPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPPWPLNR 255
PP R + + + P P PP+ + P +S PP
Sbjct: 646 PPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASR-------LSPPPEDSPT 698
Query: 256 APRRATPPAHPPPRSSSLGNSPERGPLRPFVPEQELLRSLRLCP----PHPTARLLLAAD 311
+P PA PPP S + E PL P +PE+ +LCP PH + R +
Sbjct: 699 SPPPEDSPASPPPEDSLMSLPLEESPLLP-LPEEP-----QLCPRSEGPHLSPR---PEE 749
Query: 312 PGGSPAQRRRTSSLPRSEE 330
P SP S P++EE
Sbjct: 750 PHLSPRPEEPHLS-PQAEE 767
Score = 31.2 bits (69), Expect = 1.3
Identities = 34/123 (27%), Positives = 42/123 (34%), Gaps = 19/123 (15%)
Query: 215 TPAAPARKLP------PKRAEGDIKPYSSSDREFLKVAVEPPWPLNRAPRRATPPAHPPP 268
T AAP P P A+GD P S L+ + PP N PP PP
Sbjct: 944 TAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPP 1003
Query: 269 RSSSLGNSPERGPLRPFVPEQELLRSLRLCPPHPTARLLLAADPGGSPAQRRRTSSLPRS 328
S GP P + E PP + L + P SP + +LP S
Sbjct: 1004 SPGS-----PVGPASPILMEP--------LPPQCSPLLQHSLVPQNSPPSQCSPPALPLS 1050
Query: 329 EES 331
S
Sbjct: 1051 VPS 1053
Score = 30.0 bits (66), Expect = 3.0
Identities = 23/84 (27%), Positives = 29/84 (34%), Gaps = 9/84 (10%)
Query: 195 RPPAPSLRATRHSRAAAVDPTPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEP----P 250
+PP P R+ DP PA ++ + P S F V P P
Sbjct: 2388 QPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSP 2447
Query: 251 WPLNRAPRRAT-----PPAHPPPR 269
P +R P R P H PPR
Sbjct: 2448 DPYSRPPSRPQSRDPFAPLHKPPR 2471
Score = 30.0 bits (66), Expect = 3.0
Identities = 24/73 (32%), Positives = 28/73 (38%), Gaps = 5/73 (6%)
Query: 260 ATPPAHPPPRSSSLGNSPERGPLRPFVPEQELLRSLRLCPPHPTARLLLAADPGGSPAQR 319
A PP P P S L SP P P V EL PP P+ L ++ P R
Sbjct: 4908 APPPEEPSPPPSPLAPSPASPPTEPLV---ELPTEPLAEPPVPSPLPLASSPESARPKPR 4964
Query: 320 RRTSSLPRSEESR 332
R E+SR
Sbjct: 4965 ARPPE--EGEDSR 4975
Score = 29.6 bits (65), Expect = 3.9
Identities = 26/97 (26%), Positives = 34/97 (35%), Gaps = 1/97 (1%)
Query: 195 RPPAPSLRATRHSRAAAVDPTPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPPWPLN 254
R PAP + V PTP P+ PKR P S E P P
Sbjct: 4288 RLPAPPGALSTGPVLGPVHPTPP-PSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKP 4346
Query: 255 RAPRRATPPAHPPPRSSSLGNSPERGPLRPFVPEQEL 291
+ P PP P ++ L ++ L P+ P L
Sbjct: 4347 QGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNL 4383
Score = 28.5 bits (62), Expect = 8.7
Identities = 19/49 (38%), Positives = 20/49 (40%), Gaps = 6/49 (12%)
Query: 252 PLNRAPRRATPPAHPPPRSSSLGNSPERGPLRPFVPEQELLRSLRLCPP 300
P AP P PPP S L PE P P PE + RL PP
Sbjct: 428 PQLEAPLNEEMPLLPPPEESPLSPPPEESPTSP-PPE-----ASRLSPP 470
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 38.1 bits (87), Expect = 0.011
Identities = 44/154 (28%), Positives = 59/154 (38%), Gaps = 41/154 (26%)
Query: 196 PPAPSL----RATRHSRAAAVDPT------PAAPARKL--------PPKRAEGDIKPYSS 237
PPAP L + ++ A+ DPT P AP ++ PPK A I +
Sbjct: 2137 PPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNK 2196
Query: 238 SDREFLKVAVE----------PPWPLNRAPRRATPPAHPPPRSSSLGNSPERGPLRPFVP 287
+ F+K+A E PP P +P T PP LG P G +RP P
Sbjct: 2197 LGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPP--GPLLGVLPVVGVVRPAPP 2254
Query: 288 EQELLRSLRLCPPHPTARLLLAADPGGSPAQRRR 321
PP P L+L++ P P Q R
Sbjct: 2255 -----------PPPPPLTLVLSSGPASPPRQAIR 2277
Score = 34.7 bits (78), Expect = 0.12
Identities = 29/88 (32%), Positives = 38/88 (43%), Gaps = 11/88 (12%)
Query: 250 PWPLNRAPRRATPPAHPPPRSSSLGNSPERGPLRPFVPEQELL---RSLRLC----PPHP 302
PW + +P A+P P R + G E P EQ+ L +S R C P +
Sbjct: 1029 PWDSDESPE-ASPGPPGPRRGAGAGGPREEVVAHPGPEEQDSLLQRKSARRCVKQRPSYD 1087
Query: 303 TARLLLAADPGGSPAQRRRTSSLPRSEE 330
++PGG PA RRRT PR E
Sbjct: 1088 IFEDSDDSEPGGPPAPRRRT---PRENE 1112
Score = 31.2 bits (69), Expect = 1.3
Identities = 34/125 (27%), Positives = 47/125 (37%), Gaps = 8/125 (6%)
Query: 207 SRAAAVDPTPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPPWPLNRAPRRATPPAHP 266
+R++ V TP + PPK + ++ P + P P+ PR TPP+ P
Sbjct: 534 ARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTP 593
Query: 267 PPRSSSLGNSPERGPLR-PFVPEQELLRSLRLCPPHPTARLLLAADPGGSPAQRRRTSSL 325
P R LR P L R L PP P A P +PA R L
Sbjct: 594 VPLPEK-----RRSILREPTFRWTSLTRELP--PPPPAPPPPPAPSPPPAPATSSRRPLL 646
Query: 326 PRSEE 330
R+ +
Sbjct: 647 LRAPQ 651
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 38.1 bits (87), Expect = 0.011
Identities = 44/161 (27%), Positives = 58/161 (36%), Gaps = 20/161 (12%)
Query: 177 VPQVNNFVIFEGFFAHQHRPPAPSLRATRHSRAAAVDPTPAAPARKLPPKRAEGDIKPYS 236
+P N+ E + PP P T + P P PA PP + P
Sbjct: 1439 LPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPP-PPPPPQPALPSPPPL----VAPTP 1493
Query: 237 SSDREFLKVAVEPPWPLNRAPRRATPPAHPPPRSSSLGNSPERGPLRPFVPEQEL--LRS 294
SS PP P P +PP PPP ++ L PE P P + EL R
Sbjct: 1494 SSPPP-------PPLPPPPPPAMPSPPPPPPPAAAPLAAPPEE-PAAPSPEDPELPDTRP 1545
Query: 295 LRLCPPHPTARLL-----LAADPGGSPAQRRRTSSLPRSEE 330
L L TA + A + GG R R + R+E+
Sbjct: 1546 LHLAKKQETAAVCGETDEEAGESGGEGIFRERDEFVIRAED 1586
Score = 29.3 bits (64), Expect = 5.1
Identities = 37/127 (29%), Positives = 45/127 (35%), Gaps = 21/127 (16%)
Query: 209 AAAVDPTPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPPWPLNRAPRRATPPAHPPP 268
AAAV P P LP + G +P L+ P P P+ PP PPP
Sbjct: 1427 AAAVPGPPPLPG--LPSANSNGTPEP------PLLEEKPPPTPPPAPTPQPQPPPPPPPP 1478
Query: 269 RS---------SSLGNSPERGPLRPFVPEQELLRSLRLCPPHPTARLLLAADPGGSPAQR 319
+ + +SP PL P P + S PP P A LAA P A
Sbjct: 1479 QPALPSPPPLVAPTPSSPPPPPLPP--PPPPAMPSPP--PPPPPAAAPLAAPPEEPAAPS 1534
Query: 320 RRTSSLP 326
LP
Sbjct: 1535 PEDPELP 1541
>gi|239753975 PREDICTED: hypothetical protein [Homo sapiens]
Length = 389
Score = 37.7 bits (86), Expect = 0.014
Identities = 34/96 (35%), Positives = 41/96 (42%), Gaps = 13/96 (13%)
Query: 197 PAPSLRATRHSRAAAVDPTPAAP---ARKLPP-KRAEGDIKPYSSSDREFLKVAVEP-PW 251
P S A AV P P+ P + LPP EG+ +PY+ RE A P W
Sbjct: 111 PPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRE--SPAPRPFRW 168
Query: 252 --PLNRAPRRATPP----AHPPPRSSSLGNSPERGP 281
P + AP R PP A PP R + P RGP
Sbjct: 169 GDPFSPAPPRPQPPSRPAAQPPSRPAFRSPRPVRGP 204
>gi|46909600 a disintegrin and metalloproteinase domain 15 isoform 6
preproprotein [Homo sapiens]
Length = 863
Score = 37.7 bits (86), Expect = 0.014
Identities = 36/121 (29%), Positives = 49/121 (40%), Gaps = 15/121 (12%)
Query: 197 PAPSLRA--TRHSRAAAVDPTPAAPARKLPP----KRAEGDIKPYSSSDREFLKVAVEPP 250
P P RA R ++ A+ PA P+R LPP KR + ++ +DR P
Sbjct: 746 PGPPQRALLARGTKQASALSFPAPPSRPLPPDPVSKRLQAEL-----ADRPNPPTRPLPA 800
Query: 251 WPLNRAPRRATPPAHPPPR----SSSLGNSPERGPLRPFVPEQELLRSLRLCPPHPTARL 306
P+ R+P+ P PPPR + G P P L+ R PP PT
Sbjct: 801 DPVVRSPKSQGPAKPPPPRKPLPADPQGRCPSGDLPGPGAGIPPLVVPSRPAPPPPTVSS 860
Query: 307 L 307
L
Sbjct: 861 L 861
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 37.7 bits (86), Expect = 0.014
Identities = 36/113 (31%), Positives = 44/113 (38%), Gaps = 5/113 (4%)
Query: 196 PPAPSLRATRHSRAAAV----DPTPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPPW 251
PPAP RA R + AAA PTPA P P A P +++ + P
Sbjct: 108 PPAPP-RAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQ 166
Query: 252 PLNRAPRRATPPAHPPPRSSSLGNSPERGPLRPFVPEQELLRSLRLCPPHPTA 304
P RA R A A PP ++ +P GP R P PP P A
Sbjct: 167 PGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPA 219
Score = 35.4 bits (80), Expect = 0.072
Identities = 30/100 (30%), Positives = 39/100 (39%), Gaps = 5/100 (5%)
Query: 196 PPAPSLRATRHSRAAAVDPTPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPPWPLNR 255
P P RA R + AA P PAAP PP P ++ L PP P
Sbjct: 164 PAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPL-----PPPPQPP 218
Query: 256 APRRATPPAHPPPRSSSLGNSPERGPLRPFVPEQELLRSL 295
AP + P P P+ G + G V +E++R L
Sbjct: 219 APPQQQQPPPPQPQPPPEGGAVRAGGAARPVSLREVVRYL 258
Score = 34.3 bits (77), Expect = 0.16
Identities = 33/98 (33%), Positives = 41/98 (41%), Gaps = 13/98 (13%)
Query: 196 PPAPSLRATRHSRAAAVDPTPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPPWPLNR 255
PPAP A A A P AA A PP + G +P + R +A PP P
Sbjct: 136 PPAPVAAA-----APARAPRAAAAAATAPP--SPGPAQPGPRAQRA-APLAAPPPAPA-- 185
Query: 256 APRRATPPAHP---PPRSSSLGNSPERGPLRPFVPEQE 290
AP PPA P PP + + P P +P P Q+
Sbjct: 186 APPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQ 223
>gi|46909598 a disintegrin and metalloproteinase domain 15 isoform 5
preproprotein [Homo sapiens]
Length = 862
Score = 37.4 bits (85), Expect = 0.019
Identities = 37/121 (30%), Positives = 51/121 (42%), Gaps = 16/121 (13%)
Query: 197 PAPSLRA--TRHSRAAAVDPTPAAPARKLPP----KRAEGDIKPYSSSDREFLKVAVEPP 250
P P RA R ++A+A+ PA P+R LPP KR + ++ +DR P
Sbjct: 746 PGPPQRALLARGTKASALS-FPAPPSRPLPPDPVSKRLQAEL-----ADRPNPPTRPLPA 799
Query: 251 WPLNRAPRRATPPAHPPPR----SSSLGNSPERGPLRPFVPEQELLRSLRLCPPHPTARL 306
P+ R+P+ P PPPR + G P P L+ R PP PT
Sbjct: 800 DPVVRSPKSQGPAKPPPPRKPLPADPQGRCPSGDLPGPGAGIPPLVVPSRPAPPPPTVSS 859
Query: 307 L 307
L
Sbjct: 860 L 860
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 37.4 bits (85), Expect = 0.019
Identities = 39/120 (32%), Positives = 52/120 (43%), Gaps = 8/120 (6%)
Query: 199 PSLRATRHSRAAAVDPTPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPPWPLNRAPR 258
P+L + HS A PA P R P + SSS A P+P ++A
Sbjct: 350 PTLAPSPHSLPPASSSAPAPPMR-FPYSSSSSSSAAASSSSSSSSSSA--SPFPASQA-L 405
Query: 259 RATPPAHPPPRSSSLGNSPERGPLRPFVPEQELLRSLRLCPPHPTARLLL--AADPGGSP 316
+ P + PPP S S+ N P + +P +P Q + S PP P RLL A PG P
Sbjct: 406 PSYPHSFPPPTSLSVSNQPPK-YTQPSLPSQAVW-SQGPPPPPPYGRLLANSNAHPGPFP 463
Score = 28.5 bits (62), Expect = 8.7
Identities = 19/67 (28%), Positives = 26/67 (38%), Gaps = 6/67 (8%)
Query: 253 LNRAPRRATPPAHPPPRSSSLGNSPERGPLRP---FVPEQELLRSLRLCPPHPTARLLLA 309
L++ P R P HPPP P+ P +P F P + + P P +
Sbjct: 151 LSQGPAR---PYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQ 207
Query: 310 ADPGGSP 316
A PG P
Sbjct: 208 APPGAPP 214
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 37.4 bits (85), Expect = 0.019
Identities = 39/120 (32%), Positives = 52/120 (43%), Gaps = 8/120 (6%)
Query: 199 PSLRATRHSRAAAVDPTPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPPWPLNRAPR 258
P+L + HS A PA P R P + SSS A P+P ++A
Sbjct: 350 PTLAPSPHSLPPASSSAPAPPMR-FPYSSSSSSSAAASSSSSSSSSSA--SPFPASQA-L 405
Query: 259 RATPPAHPPPRSSSLGNSPERGPLRPFVPEQELLRSLRLCPPHPTARLLL--AADPGGSP 316
+ P + PPP S S+ N P + +P +P Q + S PP P RLL A PG P
Sbjct: 406 PSYPHSFPPPTSLSVSNQPPK-YTQPSLPSQAVW-SQGPPPPPPYGRLLANSNAHPGPFP 463
Score = 28.5 bits (62), Expect = 8.7
Identities = 19/67 (28%), Positives = 26/67 (38%), Gaps = 6/67 (8%)
Query: 253 LNRAPRRATPPAHPPPRSSSLGNSPERGPLRP---FVPEQELLRSLRLCPPHPTARLLLA 309
L++ P R P HPPP P+ P +P F P + + P P +
Sbjct: 151 LSQGPAR---PYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQ 207
Query: 310 ADPGGSP 316
A PG P
Sbjct: 208 APPGAPP 214
>gi|55741675 hypothetical protein LOC22889 [Homo sapiens]
Length = 614
Score = 37.4 bits (85), Expect = 0.019
Identities = 56/203 (27%), Positives = 75/203 (36%), Gaps = 21/203 (10%)
Query: 136 GRELFQYM-LQKERVEPHQLAIDRP-SQKLLKFLNKHYNLETTVPQVNNFVIFEGFF--- 190
GRE F+ M + +P LA + + LL+ ++ Y+ V Q+N V G+
Sbjct: 286 GREAFEPMYIYISHPKPEGLAAAKKLCENLLQTVHAEYS--RFVNQINTAVPLPGYTQPS 343
Query: 191 AHQHRPPAPSLRATR-HSRAAAVDPTPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEP 249
A PP P + + V P P P + PP + P S L V P
Sbjct: 344 AISSVPPQPPYYPSNGYQSGYPVVPPPQQPVQ--PPYGVPSIVPPAVS-----LAPGVLP 396
Query: 250 PWPLNRAPRRATPPAHPPPRSSSLGNSPERGPLRPFVPEQELLRSLRLCPPHPTARLLLA 309
P P P +S G SP GP P P + L + P P L
Sbjct: 397 ALPTGVPPVPTQYPITQVQPPASTGQSPMGGPFIPAAPVKTALPAGPQPQPQPQPPL--- 453
Query: 310 ADPGGSPAQRRR-TSSLPRSEES 331
P AQ+RR T LP ES
Sbjct: 454 --PSQPQAQKRRFTEELPDERES 474
>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
Length = 701
Score = 37.4 bits (85), Expect = 0.019
Identities = 43/145 (29%), Positives = 56/145 (38%), Gaps = 22/145 (15%)
Query: 197 PAPSLR--ATRHSRAAAVDPTPAAP-ARKLPPKRAEGDIKPYSSSDREFLKVAVEPPW-- 251
PAP+L AT+ + V P PA+P + PP+ A P R + A P
Sbjct: 521 PAPALASAATKERTESEVPPRPASPKVTRSPPETA----APVEDMARRTKRPAPARPTMP 576
Query: 252 PLNRAPRRATPPAHPPPRSSSLGNSPERGPLR--------PFVPEQELLRSLRLCPPHPT 303
P + R++PPA P P S +P+ P R P VP L PP P
Sbjct: 577 PPQVSGSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAPTVPP-----PLPPTPPQPA 631
Query: 304 ARLLLAADPGGSPAQRRRTSSLPRS 328
R + SPA S P S
Sbjct: 632 RRQSRRSPASPSPASPGPASPSPVS 656
Score = 32.0 bits (71), Expect = 0.79
Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 7/81 (8%)
Query: 196 PPAPSLRATRHSRAAAVDPTPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPPWPLNR 255
PP P A R SR + P+PA+P P + + + D P ++
Sbjct: 624 PPTPPQPARRQSRRSPASPSPASPG---PASPSPVSLSNPAQVDLGAATAEGGAPEAISG 680
Query: 256 APRRATPPAHPP-PRSSSLGN 275
P TPPA PP PR SL +
Sbjct: 681 VP---TPPAIPPQPRPRSLAS 698
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 37.0 bits (84), Expect = 0.025
Identities = 46/157 (29%), Positives = 55/157 (35%), Gaps = 9/157 (5%)
Query: 175 TTVPQVNNFVIFEGFFAHQHRPPAPSLRATRHSRAAAVDPTPAAPARKLPP---KRAEGD 231
T V Q + E A + PP S A+ S + + D P PA P +R G
Sbjct: 227 TLVYQNGSIGCVENVDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGL 286
Query: 232 IKPYSSSDREFLKVAVEPPW--PLNRAPRRATPPAHPPPRSSSLGNSPERGPLRPFVPEQ 289
P SS PP P P A PPA PPP +G P P+ P
Sbjct: 287 AGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGT 346
Query: 290 ELLRSLRLCPPHPTARLLLAADPGGSPAQRRRTSSLP 326
S PPHP AA P P +LP
Sbjct: 347 PPPPSPPSFPPHPD----FAAPPPPPPPPAADYPTLP 379
>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
Length = 1295
Score = 36.2 bits (82), Expect = 0.042
Identities = 42/142 (29%), Positives = 53/142 (37%), Gaps = 25/142 (17%)
Query: 197 PAPSLRATRHSRAAAVDPTP---------AAPARKLPPKRAEGDIKPYSSSDREFLKVAV 247
P PSL R SRA + P P A PA LP K ++P
Sbjct: 1060 PVPSL-PIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPP--------- 1109
Query: 248 EPPWPLNRAPRRATPPAHPPPRSSSLGNSPERGPL-RPFVPEQELLRSLRLCPPHPTARL 306
PP P+ P R PP PPP S + +P R P P ++ P P A L
Sbjct: 1110 -PPRPV-APPTRPAPPQRPPPPSGARSPAPTRKEFGAPKSPGTTRKDNIGRSQPSPQAGL 1167
Query: 307 LLAADPGGSPAQRRRTSSLPRS 328
A PG + R + PR+
Sbjct: 1168 ---AGPGPAGYSTARPTIPPRA 1186
Score = 32.3 bits (72), Expect = 0.61
Identities = 23/88 (26%), Positives = 34/88 (38%), Gaps = 4/88 (4%)
Query: 197 PAPSLRATRHSRAAAVDPTPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPPWPLNRA 256
P + + S+ + P P P PP + + P + +E L V V P P +
Sbjct: 1205 PESQSKTSETSKGSTFLPEPLKPQAAFPP---QSSLPPPAQRLQEPL-VPVAAPMPQSGP 1260
Query: 257 PRRATPPAHPPPRSSSLGNSPERGPLRP 284
P PPPRS S + P +P
Sbjct: 1261 QPNLETPPQPPPRSRSSHSLPSEASSQP 1288
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 35.8 bits (81), Expect = 0.055
Identities = 39/140 (27%), Positives = 58/140 (41%), Gaps = 34/140 (24%)
Query: 196 PPAPSLRATRHSRAAAVD---------PTPAAPARKLPPKRAEGDIKPYSSSDREFLKVA 246
PPAP L + S A A PTP+ + PP + P+ S
Sbjct: 874 PPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQG-----PHKSPT------- 921
Query: 247 VEPPWPLNRAPRRATPPAHPPPRSSSLGNSPERGPLRPFVPE-QELLRSLRLCPPHPTAR 305
PP L+ P A PP PPPR+ + +P P +P+ + LL P +
Sbjct: 922 --PPPTLHLVPEPAAPPP-PPPRTFQMVTTP-----FPALPQPKALLERFHQVP----SG 969
Query: 306 LLLAADPGGSPAQRRRTSSL 325
++L GG+PA + ++SL
Sbjct: 970 IILQNKAGGAPAAPQTSTSL 989
Score = 33.9 bits (76), Expect = 0.21
Identities = 26/94 (27%), Positives = 33/94 (35%), Gaps = 1/94 (1%)
Query: 197 PAPSLRATRHSRAAAVDPTPAAPARKLPPKRAEGDIK-PYSSSDREFLKVAVEPPWPLNR 255
PAP+ + + P A P A +K P SS A P
Sbjct: 733 PAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLP 792
Query: 256 APRRATPPAHPPPRSSSLGNSPERGPLRPFVPEQ 289
+P PP+ PP R S+ P PL P P Q
Sbjct: 793 SPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQ 826
Score = 32.0 bits (71), Expect = 0.79
Identities = 44/160 (27%), Positives = 56/160 (35%), Gaps = 48/160 (30%)
Query: 200 SLRATRHSRAAA----VDPTPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVE------- 248
SL ++ S +AA D P+R PP IK Y + R LK+ ++
Sbjct: 1267 SLSSSSSSSSAASSLDADEDGPMPSRNRPP------IKTYEARSRIGLKLKIKQEAGLSK 1320
Query: 249 ---------------PPWPLNRAPRRATPPAHPPPRSSSLGN-------SPERGPL--RP 284
PP L A PP PPP G +PER PL P
Sbjct: 1321 VVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAP 1380
Query: 285 FVPEQELLRSLRLCPPHPTARLLLAADPGGSPAQRRRTSS 324
P L ++ R P A P G+PA R R S
Sbjct: 1381 HCPRLPLRKTYRENVGGPGA-------PEGTPAGRARGGS 1413
Score = 30.8 bits (68), Expect = 1.8
Identities = 35/139 (25%), Positives = 51/139 (36%), Gaps = 24/139 (17%)
Query: 195 RPPAPSLRATRHSRAAAVDPTPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPPWPLN 254
+P P+ + V P P AP P G +P + + P P
Sbjct: 604 QPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPL-GLQQPQAQQPPQ-------APTPQA 655
Query: 255 RAPRRATPPAHPPPRSSS-----LGNSPERGP--------LRPFVPEQELLRSLRLCPPH 301
AP +AT P P +SS LG P P L+ F+P++ + L PH
Sbjct: 656 AAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPH 715
Query: 302 ---PTARLLLAADPGGSPA 317
P + ++ A P PA
Sbjct: 716 LSVPASVIVSAPPPAQDPA 734
>gi|14149904 anthrax toxin receptor 1 isoform 1 precursor [Homo
sapiens]
Length = 564
Score = 35.8 bits (81), Expect = 0.055
Identities = 21/57 (36%), Positives = 22/57 (38%), Gaps = 6/57 (10%)
Query: 215 TPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPPWPLNRAPRRATPPAHPPPRSS 271
TP PA PP P S PP P P RA PP+ PPPR S
Sbjct: 513 TPPPPAPHCPPPPPSAPTPPIPSPPSTL------PPPPQAPPPNRAPPPSRPPPRPS 563
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 35.8 bits (81), Expect = 0.055
Identities = 47/143 (32%), Positives = 54/143 (37%), Gaps = 32/143 (22%)
Query: 193 QHRPPAPSLRATRHSRAAAVDPTPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPP-- 250
Q PPAP A H + P P P +LP +A P+ S F A PP
Sbjct: 362 QPLPPAPL--AMPH-----IKPPPTTPIPQLPAPQAHKH-PPHLSGPSPFSMNANLPPPP 413
Query: 251 --WPLNRAPRRATPPAHPPPRSSSLGNSPERGPLRPFVPEQE--LLRSLRLCPP---HPT 303
PL+ P AHPPP L P+ PL P P Q L +S L PP HP
Sbjct: 414 ALKPLSSLSTHHPPSAHPPP----LQLMPQSQPL-PSSPAQPPGLTQSQNLPPPPASHPP 468
Query: 304 ARLLLAAD----------PGGSP 316
L A PGG P
Sbjct: 469 TGLHQVAPQPPFAQHPFVPGGPP 491
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 35.8 bits (81), Expect = 0.055
Identities = 47/143 (32%), Positives = 54/143 (37%), Gaps = 32/143 (22%)
Query: 193 QHRPPAPSLRATRHSRAAAVDPTPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPP-- 250
Q PPAP A H + P P P +LP +A P+ S F A PP
Sbjct: 916 QPLPPAPL--AMPH-----IKPPPTTPIPQLPAPQAHKH-PPHLSGPSPFSMNANLPPPP 967
Query: 251 --WPLNRAPRRATPPAHPPPRSSSLGNSPERGPLRPFVPEQE--LLRSLRLCPP---HPT 303
PL+ P AHPPP L P+ PL P P Q L +S L PP HP
Sbjct: 968 ALKPLSSLSTHHPPSAHPPP----LQLMPQSQPL-PSSPAQPPGLTQSQNLPPPPASHPP 1022
Query: 304 ARLLLAAD----------PGGSP 316
L A PGG P
Sbjct: 1023 TGLHQVAPQPPFAQHPFVPGGPP 1045
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 35.8 bits (81), Expect = 0.055
Identities = 47/143 (32%), Positives = 54/143 (37%), Gaps = 32/143 (22%)
Query: 193 QHRPPAPSLRATRHSRAAAVDPTPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPP-- 250
Q PPAP A H + P P P +LP +A P+ S F A PP
Sbjct: 916 QPLPPAPL--AMPH-----IKPPPTTPIPQLPAPQAHKH-PPHLSGPSPFSMNANLPPPP 967
Query: 251 --WPLNRAPRRATPPAHPPPRSSSLGNSPERGPLRPFVPEQE--LLRSLRLCPP---HPT 303
PL+ P AHPPP L P+ PL P P Q L +S L PP HP
Sbjct: 968 ALKPLSSLSTHHPPSAHPPP----LQLMPQSQPL-PSSPAQPPGLTQSQNLPPPPASHPP 1022
Query: 304 ARLLLAAD----------PGGSP 316
L A PGG P
Sbjct: 1023 TGLHQVAPQPPFAQHPFVPGGPP 1045
>gi|4759144 solute carrier family 9 (sodium/hydrogen exchanger),
isoform 5 [Homo sapiens]
Length = 896
Score = 35.4 bits (80), Expect = 0.072
Identities = 37/125 (29%), Positives = 57/125 (45%), Gaps = 17/125 (13%)
Query: 212 VDPTPAAPARKLPPKRAEGDIKPYSSSD-REFLKVAVEPPW--PLNRAPRRATPPAHPPP 268
+ P+P ++LP K +GD+ Y SS+ + + V ++ W ++ A+PP + P
Sbjct: 751 IPPSPTCAEKELPWKSGQGDLAVYVSSETTKIVPVDMQTGWNQSISSLESLASPPCNQAP 810
Query: 269 RSSSLGNSPERGPLRPFVPEQELLRSLRLCPPHPTARLLLAADPGGSPAQRRRTSS---L 325
+ L P RG P VP L L P P R A P + A R R+ S L
Sbjct: 811 ILTCLPPHP-RGTEEPQVP-------LHL-PSDP--RSSFAFPPSLAKAGRSRSESSADL 859
Query: 326 PRSEE 330
P+ +E
Sbjct: 860 PQQQE 864
>gi|169169586 PREDICTED: hypothetical protein [Homo sapiens]
Length = 251
Score = 35.4 bits (80), Expect = 0.072
Identities = 44/142 (30%), Positives = 50/142 (35%), Gaps = 30/142 (21%)
Query: 195 RPPAPSLRATRHSRAAAVDPTPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPPWPLN 254
R P P L A R + A P PAA A PP A R L+ P
Sbjct: 37 RSPRPPLCAPRPAPGRAQSPVPAAGAVPSPPAAAH--------PARPALRGETPAPGRRG 88
Query: 255 RAPRRA-------TPPAHPPPRSSSLGNS-PERGPLRPFVPEQELLRSLRLCPPHP---- 302
RA R P +H P R +G P +GP P P + L PP P
Sbjct: 89 RATTRGEVQPSVRPPLSHRPLRGGGMGRGRPGKGP--PPNPSRRL-------PPAPPGGR 139
Query: 303 -TARLLLAADPGGSPAQRRRTS 323
T LA P A RRR S
Sbjct: 140 RTWLSALATGPAAGGAGRRRRS 161
Score = 28.9 bits (63), Expect = 6.7
Identities = 38/126 (30%), Positives = 46/126 (36%), Gaps = 24/126 (19%)
Query: 205 RHSRAAAVDPTPAAPARK-LPPKRAEGDIKPYSSSDREFLKVAVEPPWPLNRAPRRATPP 263
RHS A TPA PAR PP A +P + + A P +P A P
Sbjct: 21 RHSSRAPGTRTPATPARSPRPPLCAP---RPAPGRAQSPVPAAGAVP-----SPPAAAHP 72
Query: 264 AHP-----PPRSSSLGNSPERGPLRPFVPEQELLRSLR----------LCPPHPTARLLL 308
A P P G + RG ++P V R LR PP +R L
Sbjct: 73 ARPALRGETPAPGRRGRATTRGEVQPSVRPPLSHRPLRGGGMGRGRPGKGPPPNPSRRLP 132
Query: 309 AADPGG 314
A PGG
Sbjct: 133 PAPPGG 138
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,629,816
Number of Sequences: 37866
Number of extensions: 870913
Number of successful extensions: 6107
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 39
Number of HSP's successfully gapped in prelim test: 356
Number of HSP's that attempted gapping in prelim test: 5306
Number of HSP's gapped (non-prelim): 1012
length of query: 333
length of database: 18,247,518
effective HSP length: 103
effective length of query: 230
effective length of database: 14,347,320
effective search space: 3299883600
effective search space used: 3299883600
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.