Guide to the Human Genome
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Search of human proteins with 18375676

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|18375676 UPF2 regulator of nonsense transcripts homolog
[Homo sapiens]
         (1272 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo...  2559   0.0  
gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo...  2559   0.0  
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]            79   3e-14
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]            77   1e-13
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi...    75   5e-13
gi|22758136 MAP7 domain containing 2 [Homo sapiens]                    74   7e-13
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    74   9e-13
gi|148746195 trichohyalin [Homo sapiens]                               73   2e-12
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    72   3e-12
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    72   3e-12
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...    71   8e-12
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap...    70   1e-11
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap...    70   1e-11
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap...    70   1e-11
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi...    70   1e-11
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]                       70   2e-11
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    69   4e-11
gi|102467235 inner centromere protein antigens 135/155kDa isofor...    69   4e-11
gi|102467242 inner centromere protein antigens 135/155kDa isofor...    69   4e-11
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...    67   8e-11
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    67   1e-10
gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo sa...    67   1e-10
gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo sa...    67   1e-10
gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo sa...    67   1e-10
gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo sap...    67   1e-10
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             66   2e-10
gi|55741709 RNA binding motif protein 25 [Homo sapiens]                65   3e-10
gi|221219020 NYD-SP11 protein [Homo sapiens]                           65   3e-10
gi|4505101 microtubule-associated protein 7 [Homo sapiens]             65   3e-10
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     65   5e-10

>gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo
            sapiens]
          Length = 1272

 Score = 2559 bits (6632), Expect = 0.0
 Identities = 1272/1272 (100%), Positives = 1272/1272 (100%)

Query: 1    MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
            MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL
Sbjct: 1    MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60

Query: 61   EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 120
            EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ
Sbjct: 61   EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 120

Query: 121  MKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKT 180
            MKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKT
Sbjct: 121  MKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKT 180

Query: 181  ITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKISDVNCAVHLCSLFHQRYADFAPSL 240
            ITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKISDVNCAVHLCSLFHQRYADFAPSL
Sbjct: 181  ITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKISDVNCAVHLCSLFHQRYADFAPSL 240

Query: 241  LQVWKKHFEARKEEKTPNITKLRTDLRFIAELTIVGIFTDKEGLSLIYEQLKNIINADRE 300
            LQVWKKHFEARKEEKTPNITKLRTDLRFIAELTIVGIFTDKEGLSLIYEQLKNIINADRE
Sbjct: 241  LQVWKKHFEARKEEKTPNITKLRTDLRFIAELTIVGIFTDKEGLSLIYEQLKNIINADRE 300

Query: 301  SHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKFNLSFPPSEIISPEKQQPFQNLLKEYF 360
            SHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKFNLSFPPSEIISPEKQQPFQNLLKEYF
Sbjct: 301  SHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKFNLSFPPSEIISPEKQQPFQNLLKEYF 360

Query: 361  TSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQSLADLL 420
            TSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQSLADLL
Sbjct: 361  TSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQSLADLL 420

Query: 421  DENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDLEGGIWEDEDARNFYENLIDLKAFVPA 480
            DENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDLEGGIWEDEDARNFYENLIDLKAFVPA
Sbjct: 421  DENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDLEGGIWEDEDARNFYENLIDLKAFVPA 480

Query: 481  ILFKDNEKSCQNKESNKDDTKEAKESKENKEVSSPDDLELELENLEINDDTLELEGGDEA 540
            ILFKDNEKSCQNKESNKDDTKEAKESKENKEVSSPDDLELELENLEINDDTLELEGGDEA
Sbjct: 481  ILFKDNEKSCQNKESNKDDTKEAKESKENKEVSSPDDLELELENLEINDDTLELEGGDEA 540

Query: 541  EDLTKKLLDEQEQEDEEASTGSHLKLIVDAFLQQLPNCVNRDLIDKAAMDFCMNMNTKAN 600
            EDLTKKLLDEQEQEDEEASTGSHLKLIVDAFLQQLPNCVNRDLIDKAAMDFCMNMNTKAN
Sbjct: 541  EDLTKKLLDEQEQEDEEASTGSHLKLIVDAFLQQLPNCVNRDLIDKAAMDFCMNMNTKAN 600

Query: 601  RKKLVRALFIVPRQRLDLLPFYARLVATLHPCMSDVAEDLCSMLRGDFRFHVRKKDQINI 660
            RKKLVRALFIVPRQRLDLLPFYARLVATLHPCMSDVAEDLCSMLRGDFRFHVRKKDQINI
Sbjct: 601  RKKLVRALFIVPRQRLDLLPFYARLVATLHPCMSDVAEDLCSMLRGDFRFHVRKKDQINI 660

Query: 661  ETKNKTVRFIGELTKFKMFTKNDTLHCLKMLLSDFSHHHIEMACTLLETCGRFLFRSPES 720
            ETKNKTVRFIGELTKFKMFTKNDTLHCLKMLLSDFSHHHIEMACTLLETCGRFLFRSPES
Sbjct: 661  ETKNKTVRFIGELTKFKMFTKNDTLHCLKMLLSDFSHHHIEMACTLLETCGRFLFRSPES 720

Query: 721  HLRTSVLLEQMMRKKQAMHLDARYVTMVENAYYYCNPPPAEKTVKKKRPPLQEYVRKLLY 780
            HLRTSVLLEQMMRKKQAMHLDARYVTMVENAYYYCNPPPAEKTVKKKRPPLQEYVRKLLY
Sbjct: 721  HLRTSVLLEQMMRKKQAMHLDARYVTMVENAYYYCNPPPAEKTVKKKRPPLQEYVRKLLY 780

Query: 781  KDLSKVTTEKVLRQMRKLPWQDQEVKDYVICCMINIWNVKYNSIHCVANLLAGLVLYQED 840
            KDLSKVTTEKVLRQMRKLPWQDQEVKDYVICCMINIWNVKYNSIHCVANLLAGLVLYQED
Sbjct: 781  KDLSKVTTEKVLRQMRKLPWQDQEVKDYVICCMINIWNVKYNSIHCVANLLAGLVLYQED 840

Query: 841  VGIHVVDGVLEDIRLGMEVNQPKFNQRRISSAKFLGELYNYRMVESAVIFRTLYSFTSFG 900
            VGIHVVDGVLEDIRLGMEVNQPKFNQRRISSAKFLGELYNYRMVESAVIFRTLYSFTSFG
Sbjct: 841  VGIHVVDGVLEDIRLGMEVNQPKFNQRRISSAKFLGELYNYRMVESAVIFRTLYSFTSFG 900

Query: 901  VNPDGSPSSLDPPEHLFRIRLVCTILDTCGQYFDRGSSKRKLDCFLVYFQRYVWWKKSLE 960
            VNPDGSPSSLDPPEHLFRIRLVCTILDTCGQYFDRGSSKRKLDCFLVYFQRYVWWKKSLE
Sbjct: 901  VNPDGSPSSLDPPEHLFRIRLVCTILDTCGQYFDRGSSKRKLDCFLVYFQRYVWWKKSLE 960

Query: 961  VWTKDHPFPIDIDYMISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSK 1020
            VWTKDHPFPIDIDYMISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSK
Sbjct: 961  VWTKDHPFPIDIDYMISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSK 1020

Query: 1021 DSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLT 1080
            DSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLT
Sbjct: 1021 DSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLT 1080

Query: 1081 DSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDV 1140
            DSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDV
Sbjct: 1081 DSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDV 1140

Query: 1141 AIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWN 1200
            AIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWN
Sbjct: 1141 AIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWN 1200

Query: 1201 QQQAEQEERMRMKKLTLDINERQEQEDYQEMLQSLAQRPAPANTNRERRPRYQHPKGAPN 1260
            QQQAEQEERMRMKKLTLDINERQEQEDYQEMLQSLAQRPAPANTNRERRPRYQHPKGAPN
Sbjct: 1201 QQQAEQEERMRMKKLTLDINERQEQEDYQEMLQSLAQRPAPANTNRERRPRYQHPKGAPN 1260

Query: 1261 ADLIFKTGGRRR 1272
            ADLIFKTGGRRR
Sbjct: 1261 ADLIFKTGGRRR 1272


>gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo
            sapiens]
          Length = 1272

 Score = 2559 bits (6632), Expect = 0.0
 Identities = 1272/1272 (100%), Positives = 1272/1272 (100%)

Query: 1    MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
            MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL
Sbjct: 1    MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60

Query: 61   EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 120
            EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ
Sbjct: 61   EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 120

Query: 121  MKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKT 180
            MKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKT
Sbjct: 121  MKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKT 180

Query: 181  ITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKISDVNCAVHLCSLFHQRYADFAPSL 240
            ITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKISDVNCAVHLCSLFHQRYADFAPSL
Sbjct: 181  ITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKISDVNCAVHLCSLFHQRYADFAPSL 240

Query: 241  LQVWKKHFEARKEEKTPNITKLRTDLRFIAELTIVGIFTDKEGLSLIYEQLKNIINADRE 300
            LQVWKKHFEARKEEKTPNITKLRTDLRFIAELTIVGIFTDKEGLSLIYEQLKNIINADRE
Sbjct: 241  LQVWKKHFEARKEEKTPNITKLRTDLRFIAELTIVGIFTDKEGLSLIYEQLKNIINADRE 300

Query: 301  SHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKFNLSFPPSEIISPEKQQPFQNLLKEYF 360
            SHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKFNLSFPPSEIISPEKQQPFQNLLKEYF
Sbjct: 301  SHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKFNLSFPPSEIISPEKQQPFQNLLKEYF 360

Query: 361  TSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQSLADLL 420
            TSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQSLADLL
Sbjct: 361  TSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQSLADLL 420

Query: 421  DENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDLEGGIWEDEDARNFYENLIDLKAFVPA 480
            DENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDLEGGIWEDEDARNFYENLIDLKAFVPA
Sbjct: 421  DENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDLEGGIWEDEDARNFYENLIDLKAFVPA 480

Query: 481  ILFKDNEKSCQNKESNKDDTKEAKESKENKEVSSPDDLELELENLEINDDTLELEGGDEA 540
            ILFKDNEKSCQNKESNKDDTKEAKESKENKEVSSPDDLELELENLEINDDTLELEGGDEA
Sbjct: 481  ILFKDNEKSCQNKESNKDDTKEAKESKENKEVSSPDDLELELENLEINDDTLELEGGDEA 540

Query: 541  EDLTKKLLDEQEQEDEEASTGSHLKLIVDAFLQQLPNCVNRDLIDKAAMDFCMNMNTKAN 600
            EDLTKKLLDEQEQEDEEASTGSHLKLIVDAFLQQLPNCVNRDLIDKAAMDFCMNMNTKAN
Sbjct: 541  EDLTKKLLDEQEQEDEEASTGSHLKLIVDAFLQQLPNCVNRDLIDKAAMDFCMNMNTKAN 600

Query: 601  RKKLVRALFIVPRQRLDLLPFYARLVATLHPCMSDVAEDLCSMLRGDFRFHVRKKDQINI 660
            RKKLVRALFIVPRQRLDLLPFYARLVATLHPCMSDVAEDLCSMLRGDFRFHVRKKDQINI
Sbjct: 601  RKKLVRALFIVPRQRLDLLPFYARLVATLHPCMSDVAEDLCSMLRGDFRFHVRKKDQINI 660

Query: 661  ETKNKTVRFIGELTKFKMFTKNDTLHCLKMLLSDFSHHHIEMACTLLETCGRFLFRSPES 720
            ETKNKTVRFIGELTKFKMFTKNDTLHCLKMLLSDFSHHHIEMACTLLETCGRFLFRSPES
Sbjct: 661  ETKNKTVRFIGELTKFKMFTKNDTLHCLKMLLSDFSHHHIEMACTLLETCGRFLFRSPES 720

Query: 721  HLRTSVLLEQMMRKKQAMHLDARYVTMVENAYYYCNPPPAEKTVKKKRPPLQEYVRKLLY 780
            HLRTSVLLEQMMRKKQAMHLDARYVTMVENAYYYCNPPPAEKTVKKKRPPLQEYVRKLLY
Sbjct: 721  HLRTSVLLEQMMRKKQAMHLDARYVTMVENAYYYCNPPPAEKTVKKKRPPLQEYVRKLLY 780

Query: 781  KDLSKVTTEKVLRQMRKLPWQDQEVKDYVICCMINIWNVKYNSIHCVANLLAGLVLYQED 840
            KDLSKVTTEKVLRQMRKLPWQDQEVKDYVICCMINIWNVKYNSIHCVANLLAGLVLYQED
Sbjct: 781  KDLSKVTTEKVLRQMRKLPWQDQEVKDYVICCMINIWNVKYNSIHCVANLLAGLVLYQED 840

Query: 841  VGIHVVDGVLEDIRLGMEVNQPKFNQRRISSAKFLGELYNYRMVESAVIFRTLYSFTSFG 900
            VGIHVVDGVLEDIRLGMEVNQPKFNQRRISSAKFLGELYNYRMVESAVIFRTLYSFTSFG
Sbjct: 841  VGIHVVDGVLEDIRLGMEVNQPKFNQRRISSAKFLGELYNYRMVESAVIFRTLYSFTSFG 900

Query: 901  VNPDGSPSSLDPPEHLFRIRLVCTILDTCGQYFDRGSSKRKLDCFLVYFQRYVWWKKSLE 960
            VNPDGSPSSLDPPEHLFRIRLVCTILDTCGQYFDRGSSKRKLDCFLVYFQRYVWWKKSLE
Sbjct: 901  VNPDGSPSSLDPPEHLFRIRLVCTILDTCGQYFDRGSSKRKLDCFLVYFQRYVWWKKSLE 960

Query: 961  VWTKDHPFPIDIDYMISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSK 1020
            VWTKDHPFPIDIDYMISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSK
Sbjct: 961  VWTKDHPFPIDIDYMISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSK 1020

Query: 1021 DSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLT 1080
            DSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLT
Sbjct: 1021 DSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLT 1080

Query: 1081 DSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDV 1140
            DSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDV
Sbjct: 1081 DSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDV 1140

Query: 1141 AIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWN 1200
            AIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWN
Sbjct: 1141 AIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWN 1200

Query: 1201 QQQAEQEERMRMKKLTLDINERQEQEDYQEMLQSLAQRPAPANTNRERRPRYQHPKGAPN 1260
            QQQAEQEERMRMKKLTLDINERQEQEDYQEMLQSLAQRPAPANTNRERRPRYQHPKGAPN
Sbjct: 1201 QQQAEQEERMRMKKLTLDINERQEQEDYQEMLQSLAQRPAPANTNRERRPRYQHPKGAPN 1260

Query: 1261 ADLIFKTGGRRR 1272
            ADLIFKTGGRRR
Sbjct: 1261 ADLIFKTGGRRR 1272


>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 275

 Score = 79.0 bits (193), Expect = 3e-14
 Identities = 44/168 (26%), Positives = 90/168 (53%), Gaps = 6/168 (3%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
           +RKK    +E++     +EK   ERR    ++R K+  K   K+   +  + KK+R E +
Sbjct: 65  KRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERE 124

Query: 64  KRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKE 123
           +  K+ +ERK+K   K K  +E K+++E  K++ + ++RKK+E + KR++  +   + +E
Sbjct: 125 RENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERE 184

Query: 124 KEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKN 171
           ++E  +  +E       +KE R K +   D + +    S++   L+++
Sbjct: 185 RKERRERKKER------KKERRKKKERKKDRKTDRQTDSQVFRPLRES 226



 Score = 74.7 bits (182), Expect = 5e-13
 Identities = 49/215 (22%), Positives = 100/215 (46%), Gaps = 7/215 (3%)

Query: 7   KPASMEEKDSLPNNKEKDCS--ERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
           KP +  E +     +E++    ER     +ER K + K   K+E  K  E K+K  E  +
Sbjct: 27  KPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQR 86

Query: 65  RKKEDKERKKKDEEKVKAEEESK-----KKEEEEKKKHQEEERKKQEEQAKRQQEEEAAA 119
           +++ +KER+K+ +EK K E + +     KK++E K++ +E +++++ ++ KR++++    
Sbjct: 87  KERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKE 146

Query: 120 QMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLK 179
           + +EKE   +  +    +   R++ R +N+       E           KK     K+ K
Sbjct: 147 RKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERK 206

Query: 180 TITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKL 214
              +  R + S  F  L  S +    V  +   ++
Sbjct: 207 KDRKTDRQTDSQVFRPLRESAFNRVTVTGVFRYRI 241



 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 36/167 (21%), Positives = 91/167 (54%), Gaps = 2/167 (1%)

Query: 4   ERKKPASMEEKDSLPNNKE-KDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLED 62
           ERK+    +EK      +  K+   +R    K+R +   K   K++  K   ++K+R   
Sbjct: 53  ERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRR 112

Query: 63  DKRKKED-KERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQM 121
           +++KK++ KER+++++++ + + + ++K++  K++ +E+ER K+E + K++++EE   + 
Sbjct: 113 ERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKR 172

Query: 122 KEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSL 168
           +   +  +  +E  ER   +KE + + +   + + +     + DS +
Sbjct: 173 ERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQV 219



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 31/137 (22%), Positives = 79/137 (57%), Gaps = 4/137 (2%)

Query: 26  SERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEK----VK 81
           +E + VS     K   +  ++++  +   +K+KR  + +RK+E  +++KK  +K     +
Sbjct: 15  TELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKE 74

Query: 82  AEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLR 141
            E + K++E++ K++ ++E RK+++E+ KR++++    + K+K+E  +  +E  +R   +
Sbjct: 75  RERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERK 134

Query: 142 KELRSKNQNAPDSRPEE 158
           ++ R K +   + + E+
Sbjct: 135 RKKRRKKKRRKERKREK 151



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 38/147 (25%), Positives = 71/147 (48%), Gaps = 15/147 (10%)

Query: 6   KKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKR 65
           K+     EK+     KEK   ER+    +ER K   +   ++E  +  E K+K+    KR
Sbjct: 84  KQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKR 143

Query: 66  KKEDK-------------ERKKKDEEKVKAEEESKKKEEEEKKKHQE--EERKKQEEQAK 110
           +KE K             +RKK++ EK +     ++K+E E+K+ +E  +ERKK+  + K
Sbjct: 144 RKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKK 203

Query: 111 RQQEEEAAAQMKEKEESIQLHQEAWER 137
            ++++    +  + +    L + A+ R
Sbjct: 204 ERKKDRKTDRQTDSQVFRPLRESAFNR 230



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 36/147 (24%), Positives = 75/147 (51%), Gaps = 9/147 (6%)

Query: 29  RTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKK 88
           + +SS+   K + +L   + VS +   K     + +RKKE +ER+K+  E+ K E + ++
Sbjct: 3   KAISSRAAVKLNTEL---QMVSCSHISKPCTQRESERKKERREREKRKREREK-ERKRER 58

Query: 89  KEEEEKKKH-----QEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKE 143
            ++E+KK+      +E ERK++E + +R++  E   + ++KE+  +  ++   R   +K+
Sbjct: 59  GKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKK 118

Query: 144 LRSKNQNAPDSRPEENFFSRLDSSLKK 170
            R + +     R E     R     +K
Sbjct: 119 ERKERERENKQRRERKRKKRRKKKRRK 145



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 28/120 (23%), Positives = 63/120 (52%), Gaps = 11/120 (9%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
           ERKK    +E++    NK++   +R+    K+R K+  +   +KE  K    +KKR +++
Sbjct: 113 ERKKKKERKERER--ENKQRRERKRKKRRKKKRRKERKR---EKERGKRERKRKKRKKEE 167

Query: 64  KRKKEDKER------KKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEA 117
           + KK ++ R      +++ E + + +E  K++ +++++K   +  ++ + Q  R   E A
Sbjct: 168 REKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESA 227


>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 245

 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 52/184 (28%), Positives = 91/184 (49%), Gaps = 8/184 (4%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
           E KK    E K      +EK   ER     +ER K + K   KKE     E KK+R E +
Sbjct: 50  EGKKERESERKKER-REREKRKREREKERKRERGKKEKKGERKKEER---ERKKRRREKE 105

Query: 64  KRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKE 123
            ++ E+KE++KK E+K +     + KE E K++ + EERK++E + + +++E    + K+
Sbjct: 106 NKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKK 165

Query: 124 KEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITE 183
           +E      +E   +   RKE + + +N  + + E     R +   ++     KK +   E
Sbjct: 166 RERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERK----KKEERKKE 221

Query: 184 QQRD 187
           +Q+D
Sbjct: 222 RQKD 225



 Score = 73.9 bits (180), Expect = 9e-13
 Identities = 43/154 (27%), Positives = 87/154 (56%), Gaps = 7/154 (4%)

Query: 3   AERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDI--KLTAKKEVSKAPEDKKKRL 60
           +ERKK     EK      KE+     +     ER K++   K   +++ +K  E+K+KR 
Sbjct: 57  SERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRK 116

Query: 61  EDDKRK-----KEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE 115
           + +K++     KE KER++K+E K +  +E ++K+EE +K+ + +ERKK+E +   ++EE
Sbjct: 117 KKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEE 176

Query: 116 EAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQ 149
           E   + +++ +  + +++  ++   RKE R + +
Sbjct: 177 ERKEKERKERKKRERNRKERKKERERKERRERKK 210



 Score = 71.2 bits (173), Expect = 6e-12
 Identities = 34/113 (30%), Positives = 68/113 (60%), Gaps = 2/113 (1%)

Query: 46  KKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQ 105
           ++E+    E KK+R  + K+++ ++E++K++ EK +  E  KK+++ E+KK + E +K++
Sbjct: 42  EREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRR 101

Query: 106 EEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEE 158
            E+  ++ EE+   + KEK+E  +  +E  ER   RKE R + +     R +E
Sbjct: 102 REKENKEGEEKEKRKKKEKKERGRTSKEGKERE--RKEERKREERKERERKKE 152



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 39/141 (27%), Positives = 77/141 (54%), Gaps = 5/141 (3%)

Query: 23  KDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKA 82
           K C++    S     + +I+   + +  +  E KK+R E +KRK+E ++ +K++  K + 
Sbjct: 27  KPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEK 86

Query: 83  EEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEE-----AAAQMKEKEESIQLHQEAWER 137
           + E KK+E E KK+ +E+E K+ EE+ KR+++E+      + + KE+E   +  +E  + 
Sbjct: 87  KGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKE 146

Query: 138 HHLRKELRSKNQNAPDSRPEE 158
              +KE R K +   + +  E
Sbjct: 147 RERKKEEREKERERKERKKRE 167



 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 44/150 (29%), Positives = 85/150 (56%), Gaps = 8/150 (5%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
           +R++    +E +     K+K+  ER   +SKE  + + K   K+E  K  E KK   E+ 
Sbjct: 99  KRRREKENKEGEEKEKRKKKEKKERGR-TSKEGKERERKEERKREERKERERKK---EER 154

Query: 64  KRKKEDKERKKKDEEKV-KAEEESKKKEEEEKKKHQ---EEERKKQEEQAKRQQEEEAAA 119
           ++++E KERKK++ ++V + EEE K+KE +E+KK +   +E +K++E + +R++++E   
Sbjct: 155 EKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKK 214

Query: 120 QMKEKEESIQLHQEAWERHHLRKELRSKNQ 149
           + + K+E  +  Q  W      K  R + +
Sbjct: 215 KEERKKERQKDRQTNWREKERGKRERKERK 244



 Score = 35.0 bits (79), Expect = 0.46
 Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 1/70 (1%)

Query: 1025 EGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNK 1084
            +GE  +E+ E ++   E E + G E E  + +E++       EG+E E +  +   +  K
Sbjct: 87   KGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKE-ERKREERK 145

Query: 1085 ENETDEENTE 1094
            E E  +E  E
Sbjct: 146  ERERKKEERE 155



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 19/79 (24%), Positives = 36/79 (45%), Gaps = 1/79 (1%)

Query: 1016 DKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEEN 1075
            +K++K+   E E  ++ E++E G    E +     E  + EE +  +   +E E+E E  
Sbjct: 103  EKENKEG-EEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERK 161

Query: 1076 TDYLTDSNKENETDEENTE 1094
                 +  +  E +EE  E
Sbjct: 162  ERKKRERKQVGEKEEERKE 180


>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 123

 Score = 74.7 bits (182), Expect = 5e-13
 Identities = 36/123 (29%), Positives = 78/123 (63%), Gaps = 3/123 (2%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
           +KK    +E +     +E +  E +    KE+ K+  K   KK+ +K  E +K++ E++K
Sbjct: 1   KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60

Query: 65  RKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEK 124
           ++K  +++KK++EE+ + EEE ++++EEE+K   EE R++++++ +R++EEE   + K +
Sbjct: 61  KRKRKRKKKKEEEEREEEEEEEEEEKEEEEK---EEGRRRKKKKKRRRKEEEEEKKKKRR 117

Query: 125 EES 127
            ++
Sbjct: 118 RKT 120



 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 37/110 (33%), Positives = 72/110 (65%), Gaps = 5/110 (4%)

Query: 34  KERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEE 93
           K++ K + + T + E ++  E+K     + KRK++ KE++K+ E+K K +E  K+KE+EE
Sbjct: 3   KKKKKKETEETEETEETEEEEEK-----EGKRKEKRKEKRKEKEKKKKTKETEKRKEKEE 57

Query: 94  KKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKE 143
           ++K ++ +RKK++E+ +R++EEE   + KE+EE  +  +   ++   RKE
Sbjct: 58  EEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKE 107



 Score = 70.9 bits (172), Expect = 8e-12
 Identities = 37/118 (31%), Positives = 74/118 (62%), Gaps = 4/118 (3%)

Query: 34  KERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKA-EEESKKKEEE 92
           K++  ++ + T + E  +  E K+K    +KRK+++K++K K+ EK K  EEE KK++ +
Sbjct: 6   KKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRK 65

Query: 93  EKKKHQEEERKKQEEQA---KRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSK 147
            KKK +EEER+++EE+    K ++E+E   + K+K++  +  +E  ++   R++ + K
Sbjct: 66  RKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 33/113 (29%), Positives = 71/113 (62%)

Query: 46  KKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQ 105
           KK+  K  E+ ++  E ++ ++++ +RK+K +EK K +E+ KK +E EK+K +EEE KK+
Sbjct: 3   KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62

Query: 106 EEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEE 158
           + + K+++EEE   + +E+EE  +  +E  E    +K+ + + +   + + ++
Sbjct: 63  KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 36/120 (30%), Positives = 70/120 (58%), Gaps = 11/120 (9%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPE---DKKKRL 60
           ++KK  + E +++    +E++   +R    KE+ K+  K    KE  K  E   ++KKR 
Sbjct: 4   KKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRK 63

Query: 61  EDDKRKKEDKERKK----KDEEKVKAEEES----KKKEEEEKKKHQEEERKKQEEQAKRQ 112
              K+KKE++ER++    ++EEK + E+E     KKK++  +K+ +EE++KK+  + K++
Sbjct: 64  RKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 33/113 (29%), Positives = 64/113 (56%), Gaps = 14/113 (12%)

Query: 56  KKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEE-EEKKKHQEEERK---------KQ 105
           KKK+    K+KKE +E ++ +E + + E+E K+KE+ +EK+K +E+++K         K+
Sbjct: 1   KKKK----KKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKE 56

Query: 106 EEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEE 158
           EE+ KR+++ +   + +E+EE  +  +E  E     +  R K +     + EE
Sbjct: 57  EEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEE 109



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 30/118 (25%), Positives = 61/118 (51%), Gaps = 9/118 (7%)

Query: 70  KERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQ 129
           K++KKK E +   E E  ++EEE++ K +E+ ++K++E+ K+++ +E   + KEKEE   
Sbjct: 2   KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKE-TEKRKEKEEE-- 58

Query: 130 LHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQRD 187
                 E+   RK  + K +   +   EE    + +   ++     KK K   +++ +
Sbjct: 59  ------EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEE 110



 Score = 39.7 bits (91), Expect = 0.019
 Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 5/76 (6%)

Query: 1016 DKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEEN 1075
            +K+ K    E E  +E EEEE+      ++   E E  E EEEE     ++E EEEE+E 
Sbjct: 39   EKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEE-----EEEKEEEEKEE 93

Query: 1076 TDYLTDSNKENETDEE 1091
                    K    +EE
Sbjct: 94   GRRRKKKKKRRRKEEE 109



 Score = 38.1 bits (87), Expect = 0.054
 Identities = 23/78 (29%), Positives = 35/78 (44%)

Query: 1017 KDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENT 1076
            K  K    E E  EE EEEEE   + +E+   + +  E +++        E EEEE++  
Sbjct: 4    KKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRK 63

Query: 1077 DYLTDSNKENETDEENTE 1094
                   +E E +EE  E
Sbjct: 64   RKRKKKKEEEEREEEEEE 81



 Score = 35.8 bits (81), Expect = 0.27
 Identities = 24/94 (25%), Positives = 44/94 (46%), Gaps = 5/94 (5%)

Query: 984  RPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETE 1043
            + K K     EE+    ++ E+E   K      +  K+   + +  E+ +E+EE     E
Sbjct: 4    KKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEE-----E 58

Query: 1044 EQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTD 1077
            E+        + EEEE  + +++E EE+EEE  +
Sbjct: 59   EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKE 92



 Score = 34.3 bits (77), Expect = 0.78
 Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 24/94 (25%)

Query: 1017 KDSKDSMTEGENLEEDEEEEEGG-------------------AETEEQSGNESEVNEPEE 1057
            K  K++    E  E +EEEE+ G                    ETE++   E E  + + 
Sbjct: 5    KKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKR 64

Query: 1058 EEGSDNDDDEGEEEEEENTDYLTDSNKENETDEE 1091
            +     +++E EEEEEE      +  KE E  EE
Sbjct: 65   KRKKKKEEEEREEEEEEE-----EEEKEEEEKEE 93



 Score = 33.9 bits (76), Expect = 1.0
 Identities = 18/74 (24%), Positives = 40/74 (54%)

Query: 484 KDNEKSCQNKESNKDDTKEAKESKENKEVSSPDDLELELENLEINDDTLELEGGDEAEDL 543
           K+ E++ + +E+ +++ KE K  ++ KE     + + + +  E   +  E E   + +  
Sbjct: 8   KETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRK 67

Query: 544 TKKLLDEQEQEDEE 557
            KK  +E+E+E+EE
Sbjct: 68  KKKEEEEREEEEEE 81



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 1/79 (1%)

Query: 1017 KDSKDSMTEGENLEE-DEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEEN 1075
            K  K    E E  EE +E EEE   E + +   + +  E E+++ +   +   E+EEEE 
Sbjct: 1    KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60

Query: 1076 TDYLTDSNKENETDEENTE 1094
                    K+ E + E  E
Sbjct: 61   KRKRKRKKKKEEEEREEEE 79



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 22/82 (26%), Positives = 38/82 (46%), Gaps = 4/82 (4%)

Query: 484 KDNEKSCQNKESNKDDTKEAKESKENKEVSSPDDLELELENLEINDDTLELEGGDEAEDL 543
           ++ EK  + KE  K+  KE ++ K+ KE     + E E +  +      + E   E E+ 
Sbjct: 21  EEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEE 80

Query: 544 TKKLLDEQEQEDEEASTGSHLK 565
                +E+E+E+EE   G   K
Sbjct: 81  E----EEEEKEEEEKEEGRRRK 98


>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
          Length = 732

 Score = 74.3 bits (181), Expect = 7e-13
 Identities = 44/160 (27%), Positives = 91/160 (56%), Gaps = 3/160 (1%)

Query: 3   AERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLED 62
           AE+++ A ++++       EK+  +R      +R  ++ +L  ++E  K  E++K++ E+
Sbjct: 405 AEKRRQARLQKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEE 464

Query: 63  DKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMK 122
            K+++ +++RK  +E K KAEEE   KE++E++K ++   +KQ+E A+ +  E A     
Sbjct: 465 KKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREVAEQMRL 524

Query: 123 EKEE-SIQLHQEAWERHHLRKEL--RSKNQNAPDSRPEEN 159
           E+E+  +Q+ QE  ER     E+  R++  + P    +E+
Sbjct: 525 EREQIMLQIEQERLERKKRIDEIMKRTRKSDVPPQVKKED 564



 Score = 67.4 bits (163), Expect = 8e-11
 Identities = 37/126 (29%), Positives = 75/126 (59%), Gaps = 5/126 (3%)

Query: 23  KDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKA 82
           K  +E+R  +  ++ +++ +   K+E  +   ++ KR  +++R + ++E +K++EE+ + 
Sbjct: 402 KILAEKRRQARLQKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQ 461

Query: 83  EEESKKKEEEEKKKHQEEERKKQEE-----QAKRQQEEEAAAQMKEKEESIQLHQEAWER 137
           EEE KK+E EEK+K  EE ++K EE     + + Q+++E A   K+KE +    +E  E+
Sbjct: 462 EEEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREVAEQ 521

Query: 138 HHLRKE 143
             L +E
Sbjct: 522 MRLERE 527



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 43/135 (31%), Positives = 78/135 (57%), Gaps = 10/135 (7%)

Query: 18  PNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLE-DDKRKKEDKERKKKD 76
           P     D  E   + +++R +  ++   ++E  +  ++++ RLE ++ ++K ++ER + +
Sbjct: 390 PTAGTTDAGEAAKILAEKRRQARLQ-KEQEEQERVEKEEQDRLEREELKRKAEEERLRLE 448

Query: 77  EEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWE 136
           EE  K EEE K+ +EEEKKK + EE++K  E+AKR+ EEE    +KEK+E     QE  E
Sbjct: 449 EEARKQEEERKR-QEEEKKKQEGEEKRKAGEEAKRKAEEELL--LKEKQE-----QEKQE 500

Query: 137 RHHLRKELRSKNQNA 151
           +  + K+  +    A
Sbjct: 501 KAMIEKQKEAAETKA 515



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 33/129 (25%), Positives = 67/129 (51%), Gaps = 10/129 (7%)

Query: 1   MPAERKKPASMEEKDSLPNNKEKDC-----SERRTVSSKERPKDDIKLTAKKEVSKAPED 55
           +P +  +P ++  + S PN + +       S+ R   +KER ++  K  A +E     + 
Sbjct: 23  LPGKIAEPGAV--RTSQPNYRPQGMEGFLKSDERQRLAKERREEREKCLAAREQQILEKQ 80

Query: 56  KKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE 115
           K+ RL+ +K+ +E   R +K EE+ + E++ +   EE++K+   EE ++ E   +R  E 
Sbjct: 81  KRARLQYEKQMEE---RWRKLEEQRQREDQKRAAVEEKRKQKLREEEERLEAMMRRSLER 137

Query: 116 EAAAQMKEK 124
               ++K+K
Sbjct: 138 TQQLELKKK 146



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 24/78 (30%), Positives = 47/78 (60%), Gaps = 4/78 (5%)

Query: 53  PEDKKKRLEDDKRKKEDKERKKKDEEKVKAEE----ESKKKEEEEKKKHQEEERKKQEEQ 108
           P+  +  L+ D+R++  KER+++ E+ + A E    E +K+   + +K  EE  +K EEQ
Sbjct: 42  PQGMEGFLKSDERQRLAKERREEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQ 101

Query: 109 AKRQQEEEAAAQMKEKEE 126
            +R+ ++ AA + K K++
Sbjct: 102 RQREDQKRAAVEEKRKQK 119



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 26/143 (18%), Positives = 64/143 (44%), Gaps = 1/143 (0%)

Query: 77  EEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWE 136
           E++ +A  + +++E+E  +K +++  +++E + K ++E     +   K+E  +  QE  +
Sbjct: 406 EKRRQARLQKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEK 465

Query: 137 RHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQRDSLSHDFNGL 196
           +    +E R   + A     EE          K+  A ++K K   E +   ++     L
Sbjct: 466 KKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREVAEQMR-L 524

Query: 197 NLSKYIAEAVASIVEAKLKISDV 219
              + + +     +E K +I ++
Sbjct: 525 EREQIMLQIEQERLERKKRIDEI 547



 Score = 40.0 bits (92), Expect = 0.014
 Identities = 25/96 (26%), Positives = 54/96 (56%), Gaps = 4/96 (4%)

Query: 55  DKKKRLEDDKRKKEDK---ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKR 111
           D+++RL  ++R++ +K    R+++  EK K      +K+ EE+ +  EE+R++ E+Q + 
Sbjct: 52  DERQRLAKERREEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQRQR-EDQKRA 110

Query: 112 QQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSK 147
             EE+   +++E+EE ++           + EL+ K
Sbjct: 111 AVEEKRKQKLREEEERLEAMMRRSLERTQQLELKKK 146



 Score = 36.2 bits (82), Expect = 0.21
 Identities = 27/127 (21%), Positives = 52/127 (40%), Gaps = 17/127 (13%)

Query: 61  EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAK---------- 110
           +D  ++K +KE+  K+ E   A++ +  + EE  +KH  ++   ++  A           
Sbjct: 327 QDMPKRKAEKEKSNKEREGTLAQQAAGPQGEEALEKHVVDKHASEKHAAAAGGKAENSAA 386

Query: 111 -------RQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSR 163
                       EAA  + EK    +L +E  E+  + KE + + +     R  E    R
Sbjct: 387 LGKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERVEKEEQDRLEREELKRKAEEERLR 446

Query: 164 LDSSLKK 170
           L+   +K
Sbjct: 447 LEEEARK 453


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 73.9 bits (180), Expect = 9e-13
 Identities = 52/175 (29%), Positives = 90/175 (51%), Gaps = 21/175 (12%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKK------ 57
           E+ K   ++EK+ L   K+    ++ +    E      K+T    V  A E+K       
Sbjct: 246 EKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAA 305

Query: 58  -------KRLEDDKRKKEDKERKKKDEEK------VKAEEES--KKKEEEEKKKHQEEER 102
                  K+ +D K+KK +KE K+K+++K      VKA +E+  K KEEEE++K +EEER
Sbjct: 306 EDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEER 365

Query: 103 KKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPE 157
            K+ E+ + +++EE   + +++E   Q  +E  ER     +L +K+Q    +R E
Sbjct: 366 IKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAE 420



 Score = 54.7 bits (130), Expect = 6e-07
 Identities = 34/128 (26%), Positives = 72/128 (56%), Gaps = 9/128 (7%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERR---TVSSKERPKDDIKLTAKKEVS-----KAPED 55
           E+ +  +  E D+  + K+KD  +++       KE+ K   K T K         K  E+
Sbjct: 297 EKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEE 356

Query: 56  KKKRLEDDKRKK-EDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQE 114
           ++KR E+++ K+ E+ E K+K+EE+++ E+  +KK++E+++K + ++  K   +++R+  
Sbjct: 357 RQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREAR 416

Query: 115 EEAAAQMK 122
             A A +K
Sbjct: 417 ARAEATLK 424



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 45/187 (24%), Positives = 86/187 (45%), Gaps = 12/187 (6%)

Query: 11  MEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPED-----KKKRLEDDKR 65
           ++E+  + ++ E        + S++  K + K      +    ED     K K +   K 
Sbjct: 174 IKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKA 233

Query: 66  KKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQ----EEERKKQEEQAKRQQEEEAAA-- 119
           +K+++ERKK+DEEK K  +  +K+E E  KK Q    E +RK +EE  K +   +     
Sbjct: 234 EKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIP 293

Query: 120 QMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLK 179
             +EK E+    ++  E    +K+ + K +   + + +E       +++K     + KLK
Sbjct: 294 ASEEKAETPTAAEDDNEGDKKKKD-KKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLK 352

Query: 180 TITEQQR 186
              E+Q+
Sbjct: 353 EEEERQK 359



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 50/211 (23%), Positives = 94/211 (44%), Gaps = 18/211 (8%)

Query: 4   ERKKPASMEEKDSLPNNKEKDC------SERRTVSSKERPKDDIKLTAKKEVSKAPEDKK 57
           + KK    +E D L   +E         ++R TV+ K    ++ + T+K +  K  + KK
Sbjct: 46  KEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKK 105

Query: 58  KRLED-DKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKR----Q 112
           +  +D D  + EDK+ K K   K K E  S   ++++  K  ++ + K ++  K+    +
Sbjct: 106 QSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSE 165

Query: 113 QEEEAAAQMKEK---EESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLK 169
           ++E+ + ++KE+     S +   E+ E    RK  +   +N P    E       D+S K
Sbjct: 166 EDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDD-DASFK 224

Query: 170 KNTAFVKKLKTITEQQRDSLSHDFNGLNLSK 200
             T   KK +   +++R+    D     L K
Sbjct: 225 IKTVAQKKAE---KKERERKKRDEEKAKLRK 252



 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 56/225 (24%), Positives = 96/225 (42%), Gaps = 57/225 (25%)

Query: 14  KDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKR-----KKE 68
           K    N K K      + +  +     IK  A+K+  K   ++KKR E+  +     +KE
Sbjct: 198 KGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKE 257

Query: 69  DKERKKKDEEKVKAEEESKKKEEEEKKK--------------------------HQEEER 102
           + E  KKD+ K K   ES++K EEE  K                          ++ +++
Sbjct: 258 ELETGKKDQSKQK---ESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKK 314

Query: 103 KKQEEQAKRQQEE------------------EAAAQMKEKEESIQLHQEAWERHHLRKEL 144
           KK +++ K ++EE                  EA A++KE+EE  +  +E  ER    +EL
Sbjct: 315 KKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEE--ERIKRLEEL 372

Query: 145 RSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKL-KTITEQQRDS 188
            +K +   + R E+    R     K+    +KK  K +T+ QR++
Sbjct: 373 EAKRKE--EERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREA 415



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 30/121 (24%), Positives = 62/121 (51%), Gaps = 4/121 (3%)

Query: 52  APEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKR 111
           A +++ +++E +K   E KE  +++EE+ + EEE ++ EEEE+++ + E  +  EE  K 
Sbjct: 510 ASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKV 569

Query: 112 QQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKN 171
             E+++   + +K       + + +  +   + R+K + A D         RL+ S   N
Sbjct: 570 SDEKDSGKTLDKKPSK----EMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRLEHSKNVN 625

Query: 172 T 172
           T
Sbjct: 626 T 626



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 33/129 (25%), Positives = 66/129 (51%), Gaps = 5/129 (3%)

Query: 3   AERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLED 62
           + +K   S E++D+    KE+    R   S +   + D  L ++K   K  ++K     +
Sbjct: 157 SNKKWDGSEEDEDNSKKIKERS---RINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIE 213

Query: 63  DKRKKEDKERKKKDEEKVKAEEES--KKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 120
              + +D   K K   + KAE++   +KK +EEK K ++ + K++ E  K+ Q ++  +Q
Sbjct: 214 SGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQ 273

Query: 121 MKEKEESIQ 129
            K +EE+++
Sbjct: 274 RKFEEETVK 282



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 43/166 (25%), Positives = 71/166 (42%), Gaps = 13/166 (7%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDK--KKR-- 59
           ERKK    E K+ L   KE     +    ++ R +  +KL   + V    +D   KKR  
Sbjct: 388 ERKKQKEKERKERL--KKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPI 445

Query: 60  LEDDKRKKEDKERKKKDEEK-------VKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQ 112
            ED KRKK  ++ + K+  +       V+  E+   ++EE     + EE +  E+     
Sbjct: 446 YEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDD 505

Query: 113 QEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEE 158
            E  A+ +  EK E  ++H E  E     +E   + +   +S  EE
Sbjct: 506 WEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEE 551



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 34/129 (26%), Positives = 61/129 (47%), Gaps = 21/129 (16%)

Query: 1030 EEDEEEEEGG----------AETEEQSGNESEV------NEPEEEEGSDNDDDEGEEEEE 1073
            EE+E+ E+ G           ETE+  GN+  +       E EEEE  + +D+E EEEEE
Sbjct: 493  EEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEE 552

Query: 1074 ENTDYLTDSNKENETDEENTEVMIKGGGLKHVPCVE---DEDFIQALDKMMLENLQQRSG 1130
            E  +  ++ ++ +E DE+ ++    G  L   P  E   D ++    D+   E    ++ 
Sbjct: 553  EEGE--SEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAK 610

Query: 1131 ESVKVHQLD 1139
              ++  +L+
Sbjct: 611  RRIEKRRLE 619



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 26/67 (38%), Positives = 39/67 (58%), Gaps = 5/67 (7%)

Query: 1027 ENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDS--NK 1084
            EN EE+EEEEE   E EE   +E E  E  E EGS+ D+++ +  +E+++    D   +K
Sbjct: 529  ENPEEEEEEEE---EEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSK 585

Query: 1085 ENETDEE 1091
            E  +D E
Sbjct: 586  EMSSDSE 592



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 44/188 (23%), Positives = 79/188 (42%), Gaps = 18/188 (9%)

Query: 31  VSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKE 90
           V  KE     ++   +++   A  D  + +  D+  ++ +  K   E K   EEE +++E
Sbjct: 480 VPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEE 539

Query: 91  EEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQN 150
           EEE+ +  EEE +++ E    + +EE      EK+    L ++        KE+ S ++ 
Sbjct: 540 EEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKP------SKEMSSDSEY 593

Query: 151 APDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQRDSLSHDFNGLNLSKYIAEAVASIV 210
             D           D   K+  A+ K  + I E++R   S + N   L   I   +  + 
Sbjct: 594 DSD-----------DDRTKEERAYDKAKRRI-EKRRLEHSKNVNTEKLRAPIICVLGHVD 641

Query: 211 EAKLKISD 218
             K KI D
Sbjct: 642 TGKTKILD 649



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 28/81 (34%), Positives = 43/81 (53%), Gaps = 3/81 (3%)

Query: 1016 DKDSKDS-MTEGENLEEDEEEE--EGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEE 1072
            ++D++D+ + + E +  DEE E  EG     E   N  E  E EEEE  D + +E EEEE
Sbjct: 495  EEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEE 554

Query: 1073 EENTDYLTDSNKENETDEENT 1093
             E+     D   E  +DE+++
Sbjct: 555  GESEGSEGDEEDEKVSDEKDS 575



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 24/75 (32%), Positives = 44/75 (58%), Gaps = 1/75 (1%)

Query: 1020 KDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYL 1079
            K++  E E  EE+EEE+E   E EE+ G ESE +E +EE+   +D+ +  +  ++     
Sbjct: 528  KENPEEEEEEEEEEEEDEESEEEEEEEG-ESEGSEGDEEDEKVSDEKDSGKTLDKKPSKE 586

Query: 1080 TDSNKENETDEENTE 1094
              S+ E ++D++ T+
Sbjct: 587  MSSDSEYDSDDDRTK 601



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 21/70 (30%), Positives = 37/70 (52%)

Query: 1025 EGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNK 1084
            E E  EE+EE+EE   E EE+  +E    + E+E+ SD  D     +++ + +  +DS  
Sbjct: 534  EEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEY 593

Query: 1085 ENETDEENTE 1094
            +++ D    E
Sbjct: 594  DSDDDRTKEE 603



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 20/73 (27%), Positives = 38/73 (52%)

Query: 1015 NDKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEE 1074
            N ++ ++   E E  EE EEEEE   E+E   G+E +    +E++     D +  +E   
Sbjct: 530  NPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSS 589

Query: 1075 NTDYLTDSNKENE 1087
            +++Y +D ++  E
Sbjct: 590  DSEYDSDDDRTKE 602



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 33/93 (35%), Positives = 48/93 (51%), Gaps = 14/93 (15%)

Query: 994  EESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLE---------EDEEEEEGGAETEE 1044
            EE+   V+  E E     GL +D ++  S  E E +E         E+ EEEE   E EE
Sbjct: 484  EETPPPVEPEEEEDTEDAGL-DDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEE 542

Query: 1045 QSGNESEVNEPEEEEGSDNDDDEGEEEEEENTD 1077
                E E +E EEEE  +++  EG+EE+E+ +D
Sbjct: 543  ----EDEESEEEEEEEGESEGSEGDEEDEKVSD 571



 Score = 39.7 bits (91), Expect = 0.019
 Identities = 37/166 (22%), Positives = 73/166 (43%), Gaps = 45/166 (27%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKE-RPK----------DDIKLTAKKEVSKA 52
           ++KK     +K S  +N  ++  ++ + S K  +PK          DD     KK   KA
Sbjct: 95  DKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKA 154

Query: 53  PEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEE------EKKKHQE------- 99
            +  KK   D   + ED  +K K+  ++ +  ES  + +E       +KK+Q+       
Sbjct: 155 QKSNKKW--DGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNI 212

Query: 100 -----------------EERKKQEEQAKRQQEEEAA--AQMKEKEE 126
                            +++ +++E+ +++++EE A   ++KEKEE
Sbjct: 213 ESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEE 258



 Score = 38.5 bits (88), Expect = 0.041
 Identities = 46/232 (19%), Positives = 101/232 (43%), Gaps = 22/232 (9%)

Query: 1016 DKDSKDSMTE-GENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDD-------- 1066
            DK  KD   + GE  E+++E+++G ++   ++  E+     EEEE    +++        
Sbjct: 312  DKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEE 371

Query: 1067 -EGEEEEEENTDYLTDSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENL 1125
             E + +EEE  +      ++ + ++E  E + K G L      + +   +A  +  L+ L
Sbjct: 372  LEAKRKEEERLEQ-EKRERKKQKEKERKERLKKEGKL----LTKSQREARARAEATLKLL 426

Query: 1126 QQRSGESVKVHQLDVAIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKG--NKQQF 1183
            Q +  E      L    P++   + +K P     +  +ES +    V +  +G   K++ 
Sbjct: 427  QAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEET 486

Query: 1184 KILNVPMSSQ----LAANHWNQQQAEQE-ERMRMKKLTLDINERQEQEDYQE 1230
                 P   +       + W    +++E E++   K+ +++ E  E+E+ +E
Sbjct: 487  PPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEE 538



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 29/132 (21%), Positives = 58/132 (43%), Gaps = 26/132 (19%)

Query: 989  LCNSLEESIRQVQDL--EREFLIKLGLVNDKD---SKDSMTEGENLEEDEEEEEGGAETE 1043
            +   LEE   + Q +  +RE +      N+++   SKD   +G+  ++   ++    E E
Sbjct: 58   ILKELEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELE 117

Query: 1044 EQSGNESEVNEPEEE--EGSDNDDD-------------------EGEEEEEENTDYLTDS 1082
            ++     +  +P+ E   GSD+DDD                   +G EE+E+N+  + + 
Sbjct: 118  DKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKER 177

Query: 1083 NKENETDEENTE 1094
            ++ N + E   E
Sbjct: 178  SRINSSGESGDE 189



 Score = 36.2 bits (82), Expect = 0.21
 Identities = 29/114 (25%), Positives = 59/114 (51%), Gaps = 20/114 (17%)

Query: 33  SKERPKDDIKLTA-KKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEK------------ 79
           S++  KDDI L A   E+  A   K++  +  K KK+ KE+KK+D ++            
Sbjct: 9   SEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKK-KEKKKQDFDEDDILKELEELSL 67

Query: 80  ----VKAEEE--SKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEES 127
               +KA+ E  + K  E  +++   +++KK+ ++ K+Q  ++  ++  E ++S
Sbjct: 68  EAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDS 121



 Score = 35.4 bits (80), Expect = 0.35
 Identities = 29/155 (18%), Positives = 72/155 (46%), Gaps = 15/155 (9%)

Query: 14  KDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERK 73
           +++L   KE++  ++R    + +  ++++   K+E     E ++++ + +K +KE    K
Sbjct: 345 QEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKE--RLK 402

Query: 74  KKDEEKVKAEEESKKKEEEEKKKHQEE----------ERKKQEEQAKRQQEEEAAAQMKE 123
           K+ +   K++ E++ + E   K  Q +           +K+   + K++++     + KE
Sbjct: 403 KEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKE 462

Query: 124 KEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEE 158
             ES++L         + + +  K +  P   PEE
Sbjct: 463 VSESMELCAAV---EVMEQGVPEKEETPPPVEPEE 494



 Score = 33.9 bits (76), Expect = 1.0
 Identities = 112/653 (17%), Positives = 237/653 (36%), Gaps = 122/653 (18%)

Query: 32  SSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEE 91
           ++KE+     K   KKE  K   D+   L++ +    + +  K D E V  +     +EE
Sbjct: 31  AAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEEE 90

Query: 92  ----EEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLH---QEAWERHHLRKEL 144
               ++KKK Q+ +++  ++    + E++ +   K  +  ++++    +  + + L K+ 
Sbjct: 91  FTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKA 150

Query: 145 RSKNQNA----------PDSRPEENFFSRLDSSLK---KNTAFVKKLKTITEQQRDSLSH 191
           + K Q +           D+  +    SR++SS +   ++  F++  K   + Q++    
Sbjct: 151 KGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGP 210

Query: 192 DFNGLNLSKYIAEAVASIVEAKLKISDVNCAVHLCSLFHQRYADFAPSLLQVWKKHFEAR 251
           +    N     +  + ++ + K +  +            ++  D   + L+  K+  E  
Sbjct: 211 NIESGNEDDDASFKIKTVAQKKAEKKE----------RERKKRDEEKAKLRKLKEKEELE 260

Query: 252 KEEKTPNITKLRTDLRFIAELTIVGIFTDKEGLSLIYEQLKNIINADRESHTHVSVVISF 311
             +K  + +K +   R   E T+    T   G+    E+      A  + +         
Sbjct: 261 TGKK--DQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNE-------- 310

Query: 312 CRHCGDDIAGLVPRKVKSAAEKFNLSFPPSEIISPEKQQPFQNLLKEYFTSLTKHLKRDH 371
               GD          K   +K        E    +K+ P +  +K    +L K  + + 
Sbjct: 311 ----GD----------KKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEE 356

Query: 372 RE-------------LQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQSLAD 418
           R+             L+   ++  R+   K E  + + K+ +E      KLL  SQ  A 
Sbjct: 357 RQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREAR 416

Query: 419 LLDE--------------NMPDLPQDKPTPE--------------------EHGPGIDIF 444
              E              +   LP+ +P  E                    E    +++ 
Sbjct: 417 ARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVM 476

Query: 445 TPGKPGEYDLEGGIWEDEDARNFYENLIDLKAFVPAILFKDNEKSCQNKESNK--DDTKE 502
             G P + +    +  +E+       L D +A         +++  +  E NK   + KE
Sbjct: 477 EQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMA-------SDEETEKVEGNKVHIEVKE 529

Query: 503 AKESKENKEVSSPDDLELELENLEINDDTLELEGGDEAEDLTKKLLDEQE-------QED 555
             E +E +E    +D E E E  E  +       G E ++  +K+ DE++       +  
Sbjct: 530 NPEEEEEEEEEEEEDEESEEEEEEEGESE-----GSEGDEEDEKVSDEKDSGKTLDKKPS 584

Query: 556 EEASTGSHLKLIVDAFLQQLPNCVNRDLIDKAAMDFCMNMNTKANRKKLVRAL 608
           +E S+ S      D   ++      +  I+K  ++   N+NT+  R  ++  L
Sbjct: 585 KEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRLEHSKNVNTEKLRAPIICVL 637



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 58/253 (22%), Positives = 94/253 (37%), Gaps = 59/253 (23%)

Query: 1011 LGLVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEE 1070
            +G      S+DS  +  +L+    E EG    +EQ   +S+  + +E++  D D+D+  +
Sbjct: 1    MGKKQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILK 60

Query: 1071 EEEE--------NTDYLTDSNKENETDEEN-TEVMIKGGGLKHVPCVEDEDFIQALDKMM 1121
            E EE          D  T + K  E +EE  T    K  G K           Q+ D   
Sbjct: 61   ELEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKK--------QSFDDND 112

Query: 1122 LENLQQRSGESVKVHQLDV-------------AIPLHLKSQLRKGPPLGGGEGE------ 1162
             E L+ +  +S K  +  V              +P   K + +K      G  E      
Sbjct: 113  SEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSK 172

Query: 1163 -----------AESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWN----------Q 1201
                        ES D     + +RKG K+  K  N P  +  + N  +          Q
Sbjct: 173  KIKERSRINSSGESGDESDEFLQSRKGQKKNQK--NKPGPNIESGNEDDDASFKIKTVAQ 230

Query: 1202 QQAEQEERMRMKK 1214
            ++AE++ER R K+
Sbjct: 231  KKAEKKERERKKR 243



 Score = 31.6 bits (70), Expect = 5.1
 Identities = 31/145 (21%), Positives = 60/145 (41%), Gaps = 7/145 (4%)

Query: 56  KKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE 115
           +K + ED  +   D +    + E   A +E + ++ + KKK +++++   E+   ++ EE
Sbjct: 5   QKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEE 64

Query: 116 ---EAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNT 172
              EA     ++E       E  E     K+ + K Q       ++N    L+    K+ 
Sbjct: 65  LSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSK 124

Query: 173 AFVK-KLKTITEQQRDSLSHDFNGL 196
              K K++  +    D    DFN L
Sbjct: 125 KTAKPKVEMYSGSDDDD---DFNKL 146


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 40/154 (25%), Positives = 85/154 (55%), Gaps = 3/154 (1%)

Query: 5    RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
            +++     E++ L   +E+   E R    ++  +   +   K+E  +  E++  R E +K
Sbjct: 1044 QERERQYREEEELQQEEEQLLGEERETRRRQELERQYR---KEEELQQEEEQLLREEPEK 1100

Query: 65   RKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEK 124
            R+++++ER+ ++EE+++ EEE   +EE EK++ QE ER+ +EE+  +Q+EE+   +  EK
Sbjct: 1101 RRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEK 1160

Query: 125  EESIQLHQEAWERHHLRKELRSKNQNAPDSRPEE 158
                +L ++  E   L++E     +   + R +E
Sbjct: 1161 RRRQELERQYREEEELQQEEEQLLREEQEKRRQE 1194



 Score = 67.8 bits (164), Expect = 6e-11
 Identities = 39/143 (27%), Positives = 79/143 (55%), Gaps = 3/143 (2%)

Query: 13   EKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKER 72
            +KD L   +E+   E R    K R ++  +   ++E  +  E++    E + R++++ ER
Sbjct: 1022 KKDELQQEEEQLLREER---EKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELER 1078

Query: 73   KKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQ 132
            + + EE+++ EEE   +EE EK++ QE ER+ +EE+  +Q+EE+   + +EK    +L +
Sbjct: 1079 QYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELER 1138

Query: 133  EAWERHHLRKELRSKNQNAPDSR 155
            +  E   +++E     +  P+ R
Sbjct: 1139 QYREEEEVQQEEEQLLREEPEKR 1161



 Score = 67.8 bits (164), Expect = 6e-11
 Identities = 37/129 (28%), Positives = 74/129 (57%), Gaps = 1/129 (0%)

Query: 29   RTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKK 88
            R    K R ++  +   ++E  +  E++  R E +KR++++ ER+ ++EE+V+ EEE   
Sbjct: 1095 REEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLL 1154

Query: 89   KEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKN 148
            +EE EK++ QE ER+ +EE+  +Q+EE+   + +EK    +  ++  E   L+++ R + 
Sbjct: 1155 REEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQ-ERERQYREEEELQRQKRKQR 1213

Query: 149  QNAPDSRPE 157
                D R +
Sbjct: 1214 YRDEDQRSD 1222



 Score = 67.4 bits (163), Expect = 8e-11
 Identities = 42/193 (21%), Positives = 98/193 (50%), Gaps = 21/193 (10%)

Query: 12   EEKDSLPNNKEKDCSERRTVSSKER-----------------PKDDIKLTAKKEVSKAPE 54
            EE+D L  ++E+  S+ +    K R                 P    +L  ++++ +  E
Sbjct: 851  EEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEE 910

Query: 55   DKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQE 114
            ++ +R E +KR+++++ER+ ++EE+++ EEE   +EE EK++ QE ER+ ++++  +Q+E
Sbjct: 911  EELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKE 970

Query: 115  EEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAF 174
            E+   +  EK       QE  +++   +EL+ + +       E+      +   +K    
Sbjct: 971  EQLLGEEPEKRR----RQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDEL 1026

Query: 175  VKKLKTITEQQRD 187
             ++ + +  ++R+
Sbjct: 1027 QQEEEQLLREERE 1039



 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 39/155 (25%), Positives = 83/155 (53%), Gaps = 3/155 (1%)

Query: 4    ERKKPASMEEKDSLPNNKEKDCSERRTVSS---KERPKDDIKLTAKKEVSKAPEDKKKRL 60
            ER+K    E +     +K+    E + +     K R ++  K   ++E  +  E++  R 
Sbjct: 947  EREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLRE 1006

Query: 61   EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 120
            E +KR++++ ER+ + +++++ EEE   +EE EK++ QE ER+ +EE+  +Q+EE+   +
Sbjct: 1007 EREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGE 1066

Query: 121  MKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSR 155
             +E     +L ++  +   L++E     +  P+ R
Sbjct: 1067 ERETRRRQELERQYRKEEELQQEEEQLLREEPEKR 1101



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 37/156 (23%), Positives = 88/156 (56%), Gaps = 3/156 (1%)

Query: 5    RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
            RK+   ++E++     +E++   R+    + R ++ ++   ++++ +   +K++R E ++
Sbjct: 900  RKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQ-QEEEQLLREEREKRRRQERER 958

Query: 65   RKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEK 124
            + ++DK+ ++K+E+ +  E E ++++E EKK  +EEE +++EEQ  R++ E+   Q  E+
Sbjct: 959  QYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWER 1018

Query: 125  E--ESIQLHQEAWERHHLRKELRSKNQNAPDSRPEE 158
            +  +  +L QE  +     +E R   +     R EE
Sbjct: 1019 QYRKKDELQQEEEQLLREEREKRRLQERERQYREEE 1054



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 36/181 (19%), Positives = 98/181 (54%), Gaps = 14/181 (7%)

Query: 12  EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE 71
           EE++ L   + ++    R    +E  +   +L  ++++ +  E++++  ++++R+++++ 
Sbjct: 273 EEEEQLRKLERQELRRER----QEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERR 328

Query: 72  RKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLH 131
            ++++  + +   E +++ E++ ++ QEEER+  E+Q +R+QEEE   Q   +E+ ++  
Sbjct: 329 EQQEERREQQLRREQEERREQQLRREQEEERR--EQQLRREQEEERREQQLRREQQLRRE 386

Query: 132 QEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQRDSLSH 191
           Q+      LR+E + + +     R E+    R +  L++     ++L+   E++R    H
Sbjct: 387 QQLRREQQLRREQQLRREQ--QLRREQQL--RREQQLRRE----QQLRREQEEERHEQKH 438

Query: 192 D 192
           +
Sbjct: 439 E 439



 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 40/140 (28%), Positives = 78/140 (55%), Gaps = 5/140 (3%)

Query: 4    ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
            ER+K     E++ L   +E+   E R    K R ++  +   KK+  +  E++  R E +
Sbjct: 985  EREK--KYREEEELQQEEEQLLREER---EKRRRQEWERQYRKKDELQQEEEQLLREERE 1039

Query: 64   KRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKE 123
            KR+ +++ER+ ++EE+++ EEE    EE E ++ QE ER+ ++E+  +Q+EE+   +  E
Sbjct: 1040 KRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPE 1099

Query: 124  KEESIQLHQEAWERHHLRKE 143
            K    +  ++  E   L++E
Sbjct: 1100 KRRRQERERQCREEEELQQE 1119



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 35/131 (26%), Positives = 75/131 (57%), Gaps = 3/131 (2%)

Query: 13   EKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKER 72
            E++ L   +E+   E R    K R ++  +   K +  +  E++    E +KR+++++E+
Sbjct: 932  EEEQLQQEEEQLLREER---EKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREK 988

Query: 73   KKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQ 132
            K ++EE+++ EEE   +EE EK++ QE ER+ +++   +Q+EE+   + +EK    +  +
Sbjct: 989  KYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERER 1048

Query: 133  EAWERHHLRKE 143
            +  E   L++E
Sbjct: 1049 QYREEEELQQE 1059



 Score = 60.8 bits (146), Expect = 8e-09
 Identities = 42/192 (21%), Positives = 97/192 (50%), Gaps = 18/192 (9%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPE---DKKKRL 60
           E ++   +  +  L   +E+     + +  +++ + + +L  ++++ +  +   +++ R 
Sbjct: 370 EERREQQLRREQQL--RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 427

Query: 61  EDDKRKKEDKERKKKDEEKVKAEEESKK---KEEEEKKKHQEEERKKQEEQAKRQQEEEA 117
           E ++ + E K  +++ E+++K E+E ++   K EEE ++H++E RK   +Q KR QEEE 
Sbjct: 428 EQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRK---QQLKRDQEEER 484

Query: 118 AAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKK 177
             +  + EE  +  Q+      LR+E   + +     + EE    RL   L+      ++
Sbjct: 485 RERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEE---ERLQQRLRSE----QQ 537

Query: 178 LKTITEQQRDSL 189
           L+   E++R+ L
Sbjct: 538 LRREQEERREQL 549



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 44/175 (25%), Positives = 91/175 (52%), Gaps = 22/175 (12%)

Query: 4    ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
            E++      E+  L   ++  C ER     ++R +   +   ++++S+   D+K R E+ 
Sbjct: 1380 EQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFRE--EEQQLSRQERDRKFREEEQ 1437

Query: 64   KRKKEDKERKKKDEE---------KVKAEEESKKKEEEEKKKHQEEERK--KQEEQAKRQ 112
            + +++++ERK  +EE         K + EE+  ++ EE++   QE +RK  ++E+Q +RQ
Sbjct: 1438 QVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQ 1497

Query: 113  Q------EEEAAAQMKEK---EESIQLHQEAWERHHLRKELRSKNQNAPDSRPEE 158
            +      E+E  +Q  E+   EE  QLH++  +R  L++E + + Q     R ++
Sbjct: 1498 ERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQD 1552



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 43/185 (23%), Positives = 94/185 (50%), Gaps = 14/185 (7%)

Query: 21   KEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE---RKKKDE 77
            +E+    R+ +  K R ++ ++   ++E  +  E  +K LE+++ + E +E   R+++ +
Sbjct: 1711 QEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERD 1770

Query: 78   EKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEK-------EESIQL 130
             K + EE+ +++ EE++ + QE +RK +EE+  RQ+ EE   + +++       EE +QL
Sbjct: 1771 RKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQL 1830

Query: 131  -HQEAWERHHLRKELRSKNQNAPDS---RPEENFFSRLDSSLKKNTAFVKKLKTITEQQR 186
              QE   R    ++ R++ Q A      R E+  +   +   ++      + + I  QQ+
Sbjct: 1831 EEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQK 1890

Query: 187  DSLSH 191
            +   H
Sbjct: 1891 EEQRH 1895



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 42/195 (21%), Positives = 99/195 (50%), Gaps = 11/195 (5%)

Query: 3    AERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLED 62
            A+R+   S EEK  L   +E+    R+    K R ++ +    +++  +  E  +K  E+
Sbjct: 1307 AKRRDRKSQEEKQLLREEREEK-RRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREE 1365

Query: 63   DKRKKEDKERKKKDEEKVKAEEESKK-KEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQM 121
            + R +E   +  ++E++++ +E  +K  +EE++ + QE E++ ++++ ++ +EEE     
Sbjct: 1366 ELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSR 1425

Query: 122  KE-----KEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSS----LKKNT 172
            +E     +EE  Q+ ++  ER  L +E + + +     R EE      +       +++ 
Sbjct: 1426 QERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDR 1485

Query: 173  AFVKKLKTITEQQRD 187
             F+++ + +  Q+RD
Sbjct: 1486 KFLEEEQQLRRQERD 1500



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 39/163 (23%), Positives = 82/163 (50%), Gaps = 14/163 (8%)

Query: 12  EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRK---KE 68
           +E++      E++  E+R    +E  +D +K           E++ +R E ++RK   K 
Sbjct: 429 QEEERHEQKHEQERREQRLKREQEERRDWLKR----------EEETERHEQERRKQQLKR 478

Query: 69  DKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESI 128
           D+E ++++      EEE ++++E  +++ + E+ +++E++ KRQ+EEE   Q    E+ +
Sbjct: 479 DQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQL 538

Query: 129 QLHQEAWERHHLRKELRSK-NQNAPDSRPEENFFSRLDSSLKK 170
           +  QE      L++E   +  Q   + R +     R D  LK+
Sbjct: 539 RREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKR 581



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 48/206 (23%), Positives = 107/206 (51%), Gaps = 29/206 (14%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL--- 60
           E ++    E ++     ++++  E+R    +E  +   +L +++++ +  E+++++L   
Sbjct: 493 EEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKR 552

Query: 61  EDDKRKKEDK--ERKKKDEEK-----VKAEEESK----KKEEEEKK----KHQEEERKKQ 105
           E++KR ++++  +R K+++E+     +K EEE +    K+E+EE+     K +E ER +Q
Sbjct: 553 EEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQ 612

Query: 106 EE----QAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFF 161
           EE    + KR++ EE   Q   K E     QE   +  LR+E + + +       EE   
Sbjct: 613 EERREQRLKREEPEEERRQQLLKSE----EQEERRQQQLRREQQERREQRLKREEEE--- 665

Query: 162 SRLDSSLKKNTAFVKKLKTITEQQRD 187
            RL+  LK+     ++ + + E++++
Sbjct: 666 ERLEQRLKREHEEERREQELAEEEQE 691



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 41/172 (23%), Positives = 84/172 (48%), Gaps = 10/172 (5%)

Query: 4    ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
            E+++    +     P  ++ +  E++    ++R   + K   ++E     E+K++R E D
Sbjct: 1280 EQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREE----REEKRRRQETD 1335

Query: 64   KRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERK-KQEEQAKRQQEEE-----A 117
            ++ +E+++  ++ EE+    +E  +K  EE+ +HQE+ RK  +EEQ  R+QE E      
Sbjct: 1336 RKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKE 1395

Query: 118  AAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLK 169
              Q++ +E   QL Q+   +    ++  S+ +     R EE    R +   K
Sbjct: 1396 EQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERK 1447



 Score = 57.8 bits (138), Expect = 7e-08
 Identities = 38/170 (22%), Positives = 87/170 (51%), Gaps = 9/170 (5%)

Query: 6    KKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKR 65
            +K   +++K+     +E +  +RR    +++ +++ +L  ++E     E +K+R ++ +R
Sbjct: 961  RKDKKLQQKEEQLLGEEPE--KRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWER 1018

Query: 66   KKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMK--- 122
            +   K+  +++EE++  EE  K++ +E +++++EEE  +QEE+    +E E   + +   
Sbjct: 1019 QYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELER 1078

Query: 123  --EKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKK 170
               KEE +Q  +E   R    K  R + +     R EE      +  L++
Sbjct: 1079 QYRKEEELQQEEEQLLREEPEKRRRQERER--QCREEEELQQEEEQLLRE 1126



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 42/181 (23%), Positives = 91/181 (50%), Gaps = 20/181 (11%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKR---- 59
           E ++     E++      +++  ERR    +E   +  +   +K+  K  +++++R    
Sbjct: 430 EEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWL 489

Query: 60  -LEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQ---EEQAKRQQEE 115
            LE+++R+++ + R    E++++ E+E ++  E+  K+ +EEER +Q    EQ  R+++E
Sbjct: 490 KLEEEERREQQERR----EQQLRREQEERR--EQRLKRQEEEERLQQRLRSEQQLRREQE 543

Query: 116 EAAAQMKEKEESIQLHQE------AWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLK 169
           E   Q+ ++EE  +L QE        E+   R +L  + +     R +     RL+  LK
Sbjct: 544 ERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLK 603

Query: 170 K 170
           +
Sbjct: 604 R 604



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 37/140 (26%), Positives = 75/140 (53%), Gaps = 10/140 (7%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
           +R K    E +D L   +E    ERR    K   ++ ++   K+E  +  E +++R +  
Sbjct: 565 QRLKREQEERRDQLLKREE----ERRQQRLKREQEERLEQRLKREEVERLEQEERREQRL 620

Query: 64  KRKKEDKERKK---KDEEKVKAEEESKKKEEEEKKKH---QEEERKKQEEQAKRQQEEEA 117
           KR++ ++ER++   K EE+ +  ++  ++E++E+++    +EEE ++ E++ KR+ EEE 
Sbjct: 621 KREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEER 680

Query: 118 AAQMKEKEESIQLHQEAWER 137
             Q   +EE  Q  +    R
Sbjct: 681 REQELAEEEQEQARERIKSR 700



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 39/154 (25%), Positives = 85/154 (55%), Gaps = 14/154 (9%)

Query: 22  EKDCSERRTVSSKERPKDDI-KLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKV 80
           E++  E+R    +E  +D + K   ++   +   ++++RLE  + K+E+ ER +++E + 
Sbjct: 559 EQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQ-RLKREEVERLEQEERR- 616

Query: 81  KAEEESKKKEEEEKKKHQ----EEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWE 136
             E+  K++E EE+++ Q    EE+ +++++Q +R+Q+E    ++K +EE  +L Q    
Sbjct: 617 --EQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKR 674

Query: 137 RHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKK 170
            H   +E R + + A +   +E    R+ S + K
Sbjct: 675 EH---EEERREQELAEEE--QEQARERIKSRIPK 703



 Score = 54.7 bits (130), Expect = 6e-07
 Identities = 44/193 (22%), Positives = 91/193 (47%), Gaps = 16/193 (8%)

Query: 5    RKKPASMEEKDSLPNNKEKDCS-ERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
            R + +  + +  L   +E+D   ERR    ++R   + +   ++E  +A    +K  E+ 
Sbjct: 1259 RDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEK 1318

Query: 64   KRKKEDKERKKKDEE---KVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQ------E 114
            +  +E++E K++ +E   K + EE+  ++ EE+  + QE +RK +EE+ + Q+      E
Sbjct: 1319 QLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLE 1378

Query: 115  EEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAF 174
            EE   + +E+E      ++        ++LR         R EE   SR +   K    F
Sbjct: 1379 EEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDR--KFREEEQQLSRQERDRK----F 1432

Query: 175  VKKLKTITEQQRD 187
             ++ + +  Q+R+
Sbjct: 1433 REEEQQVRRQERE 1445



 Score = 54.7 bits (130), Expect = 6e-07
 Identities = 37/154 (24%), Positives = 82/154 (53%), Gaps = 19/154 (12%)

Query: 13   EKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKER 72
            E++ L   +E+    R+    K R ++ ++   +++  ++ E  +K  E+++ ++E +E+
Sbjct: 1751 EEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQ 1810

Query: 73   KKKDEE---KVKAEEESKKKEEEEKKKHQE-------------EERKKQEEQAKRQQEEE 116
            + + ++   K + EEE  + EE+E++  QE             +E+ ++EEQ   Q+EE+
Sbjct: 1811 QLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQ 1870

Query: 117  AAAQMKE---KEESIQLHQEAWERHHLRKELRSK 147
               Q +E   +EE I+  Q+  +RH    E++S+
Sbjct: 1871 KRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQ 1904



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 35/152 (23%), Positives = 81/152 (53%), Gaps = 6/152 (3%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKK--EVSKAPEDKKKR-- 59
           + +K   +E++D    ++E     +     +ER  ++ +L + K  E  + P++++ R  
Sbjct: 154 QSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRR 213

Query: 60  --LEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEA 117
             LE  ++ +E+K++++++ +    +EE +K+  + +   ++EE K QEE+ +RQ+E + 
Sbjct: 214 ELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQE 273

Query: 118 AAQMKEKEESIQLHQEAWERHHLRKELRSKNQ 149
             +   K E  +L +E  E    ++ LR + Q
Sbjct: 274 EEEQLRKLERQELRRERQEEEQQQQRLRREQQ 305



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 24/159 (15%), Positives = 82/159 (51%)

Query: 12  EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE 71
           +E++       ++   RR    + R + + +   ++   +  E ++++L  ++ ++ +++
Sbjct: 291 QEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQ 350

Query: 72  RKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLH 131
            +++ EE+ + ++  +++EEE +++    E++ + EQ  R++++    Q   +E+ ++  
Sbjct: 351 LRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 410

Query: 132 QEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKK 170
           Q+      LR+E + + +   +   +++   R +  LK+
Sbjct: 411 QQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKR 449



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 46/202 (22%), Positives = 97/202 (48%), Gaps = 23/202 (11%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
           +R K    E +D L   +E +  E+     K++ K D +   ++   K  E++++  ++ 
Sbjct: 445 QRLKREQEERRDWLKREEETERHEQER--RKQQLKRDQEEERRERWLKLEEEERREQQER 502

Query: 64  KRKKEDKERKKKDEEKVKAEEESK------------KKEEEEKK----KHQEE---ERKK 104
           + ++  +E++++ E+++K +EE +            ++E+EE++    K +EE   E+++
Sbjct: 503 REQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER 562

Query: 105 QEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRL 164
           +E++ KR+QEE     +K +EE  Q  Q        R E R K +       EE    RL
Sbjct: 563 REQRLKREQEERRDQLLKREEERRQ--QRLKREQEERLEQRLKREEVERLEQEERREQRL 620

Query: 165 DSSLKKNTAFVKKLKTITEQQR 186
                +     + LK+  +++R
Sbjct: 621 KREEPEEERRQQLLKSEEQEER 642



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 30/123 (24%), Positives = 76/123 (61%), Gaps = 10/123 (8%)

Query: 12   EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE 71
            EE+  L   +EK    R+ +  + R +++++   ++ + + PE  K+R ++ +R+  ++E
Sbjct: 1119 EEEQLLREEREK--RRRQELERQYREEEEVQQEEEQLLREEPE--KRRRQELERQYREEE 1174

Query: 72   RKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMK-----EKEE 126
              +++EE++  EE+ K+++E E++  +EEE ++Q+ + +R ++E+  + +K     EKE 
Sbjct: 1175 ELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRK-QRYRDEDQRSDLKWQWEPEKEN 1233

Query: 127  SIQ 129
            +++
Sbjct: 1234 AVR 1236



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 41/181 (22%), Positives = 89/181 (49%), Gaps = 15/181 (8%)

Query: 21   KEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK--RKKEDKERKKKDEE 78
            +E+   + R      R + D K   +++  +  E ++K +ED++  R++E +++ +++ +
Sbjct: 1559 EEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERD 1618

Query: 79   KVKAEEESKKKEEEEKKKHQEEERKK---QEEQAKRQQEEEAAAQMKEKE--ESIQLHQE 133
            +   E+E   +E EE++ H++E  +K   +E Q +RQ+ E+     ++++  E  QL QE
Sbjct: 1619 RKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQE 1678

Query: 134  AWERHHLRKE----LRSKNQNAPDSRPEENFFSRLD----SSLKKNTAFVKKLKTITEQQ 185
              E+   R+E     R + Q       E  F           L++     ++L+  TEQ+
Sbjct: 1679 GEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQE 1738

Query: 186  R 186
            +
Sbjct: 1739 Q 1739



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 42/182 (23%), Positives = 91/182 (50%), Gaps = 11/182 (6%)

Query: 5    RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
            +++     E++ L   +E+   E R    K R ++  +   ++E  +  E++  R E +K
Sbjct: 1104 QERERQCREEEELQQEEEQLLREER---EKRRRQELERQYREEEEVQQEEEQLLREEPEK 1160

Query: 65   RKKEDKERKKKDEEKVKAEEESKKKEEEEK-KKHQEEERKKQEEQAKRQQEEEAAAQMKE 123
            R++++ ER+ ++EE+++ EEE   +EE+EK +  QE ER+ +EE+  ++Q+ +   + ++
Sbjct: 1161 RRRQELERQYREEEELQQEEEQLLREEQEKRR--QERERQYREEEELQRQKRKQRYRDED 1218

Query: 124  KEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITE 183
            +   ++     W+    ++     N+     R  E F    DS L+   +       + E
Sbjct: 1219 QRSDLK-----WQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGE 1273

Query: 184  QQ 185
            QQ
Sbjct: 1274 QQ 1275



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 33/164 (20%), Positives = 84/164 (51%), Gaps = 9/164 (5%)

Query: 4    ERKKPASMEEKDSLPNNKEKDCSE------RRTVSSKERPKDDIKLTAKKEVSKAPEDKK 57
            ER +   +EE+      +E+   E      R+    + R + D K    +++ +  E+++
Sbjct: 1576 ERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQ 1635

Query: 58   KRLEDDKRK---KEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQE 114
               ++  RK   +E + R+++ E++++ + + K +EEE+  +  EE++ +++E+ ++ +E
Sbjct: 1636 LHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFRE 1695

Query: 115  EEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEE 158
            EE   + +E+E      ++   R  L ++ R + Q   ++  E+
Sbjct: 1696 EEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQ 1739



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 48/205 (23%), Positives = 96/205 (46%), Gaps = 23/205 (11%)

Query: 2   PAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLE 61
           P +R++    E++  L   +E+   + R +  ++R + D +L  +++  +  E+++   E
Sbjct: 133 PGQRRRQKRQEQERELAEGEEQSEKQER-LEQRDRQRRDEELWRQRQEWQEREERRAEEE 191

Query: 62  DDKRKKEDKERKKKDEEKVKAEE--ESKKKEEEEKKKHQEEERKK---QEEQAK------ 110
             +  K  +  +  DEE+++  E  E ++K  EEK++ Q  ER+    QEE+ K      
Sbjct: 192 QLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQ-QRRERQDRVFQEEEEKEWRKRE 250

Query: 111 --------RQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFS 162
                   + QEEE   Q + +EE  QL +   ER  LR+E + + Q     R E+    
Sbjct: 251 TVLRKEEEKLQEEEPQRQRELQEEEEQLRK--LERQELRRERQEEEQQQQRLRREQQLRR 308

Query: 163 RLDSSLKKNTAFVKKLKTITEQQRD 187
           + +   ++     ++ +   EQQ +
Sbjct: 309 KQEEERREQQEERREQQERREQQEE 333



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 43/187 (22%), Positives = 94/187 (50%), Gaps = 19/187 (10%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
           R++    E++        ++  E R     E+ + + +L  K+E  +  +  K+  E ++
Sbjct: 409 REQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRL--KREQEERRDWLKREEETER 466

Query: 65  RKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQE--EERKKQEEQAKRQQEEEAAAQMK 122
            ++E ++++ K +++ +  E   K EEEE+++ QE  E++ ++E++ +R+Q      ++K
Sbjct: 467 HEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQ------RLK 520

Query: 123 EKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTIT 182
            +EE  +L Q       LR+E   + +     R EE    RL+   ++     ++LK   
Sbjct: 521 RQEEEERLQQRLRSEQQLRREQEERREQLL-KREEE---KRLEQERRE-----QRLKREQ 571

Query: 183 EQQRDSL 189
           E++RD L
Sbjct: 572 EERRDQL 578



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 32/119 (26%), Positives = 66/119 (55%), Gaps = 23/119 (19%)

Query: 54   EDKKKRLEDDKRKKEDKERKKKDEEKVKAEEES----------KKKEEEEKKKHQEEERK 103
            E + +R E  +++++D++RK ++EE+++ E E           K + EE+K + QE+ERK
Sbjct: 1537 EQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERK 1596

Query: 104  --KQEEQAKRQQEEEAAAQMKEKE-----------ESIQLHQEAWERHHLRKELRSKNQ 149
              + E+Q +RQ+ ++   Q ++++           E  QLH++  +R  L +E + + Q
Sbjct: 1597 FMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQ 1655



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 44/181 (24%), Positives = 95/181 (52%), Gaps = 12/181 (6%)

Query: 11   MEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPE-DKKKRLEDDKRKKED 69
            +EE+  L   +E++   R     K R ++ +    +++  +  E D+K R E+ + ++++
Sbjct: 1646 LEEEPQL-RRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQE 1704

Query: 70   KERKKKDEEKV--KAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEES 127
            +ERK   EE+   + E E K +EEE+ ++  E+E+ +++E+ ++  EEE   Q++ + E 
Sbjct: 1705 RERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEE---QLRPEREE 1761

Query: 128  IQLHQEAWERHHLRKE-LRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQR 186
             QL ++  +R    +E LR + +       E +   R +  L++     ++ + +  QQR
Sbjct: 1762 QQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQE----REEQQLRPQQR 1817

Query: 187  D 187
            D
Sbjct: 1818 D 1818



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 44/198 (22%), Positives = 99/198 (50%), Gaps = 18/198 (9%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
           E ++      K  L  ++E++  ER     +E  ++  +   ++E     E +++R +  
Sbjct: 463 ETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQE---RREQQLRREQEERREQRL 519

Query: 64  KRKKEDK--ERKKKDEEKVKAEEESKK----KEEEEKKKHQEEE----RKKQEEQ----A 109
           KR++E++  +++ + E++++ E+E ++    K EEEK+  QE      +++QEE+     
Sbjct: 520 KRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLL 579

Query: 110 KRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLK 169
           KR++E       +E+EE ++   +  E   L +E R + Q      PEE    +L  S +
Sbjct: 580 KREEERRQQRLKREQEERLEQRLKREEVERLEQEER-REQRLKREEPEEERRQQLLKSEE 638

Query: 170 KNTAFVKKLKTITEQQRD 187
           +     ++L+   +++R+
Sbjct: 639 QEERRQQQLRREQQERRE 656



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 31/144 (21%), Positives = 76/144 (52%), Gaps = 8/144 (5%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKD-----DIKLTAKKEVSKAPEDKKKR 59
           R +     E+  LP  +EK   E+R    +ER K+     + +   ++E ++  ++++  
Sbjct: 799 RAEERQQREQRFLPEEEEK---EQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDG 855

Query: 60  LEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAA 119
           L++D+ ++  +E+++  + + + EEE K++      K   +E+ ++E+Q  +++EEE   
Sbjct: 856 LQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQR 915

Query: 120 QMKEKEESIQLHQEAWERHHLRKE 143
           + +EK    +  ++  E   L++E
Sbjct: 916 EEREKRRRQEQERQYREEEQLQQE 939



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 30/156 (19%), Positives = 83/156 (53%), Gaps = 10/156 (6%)

Query: 40  DIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERK---KKDEEKVKAEE-----ESKKKEE 91
           +++   ++E  +   +++ R+  ++ +KE ++R+   +K+EEK++ EE     E +++EE
Sbjct: 217 ELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEE 276

Query: 92  EEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNA 151
           + +K  ++E R++++E+ ++QQ      Q++ K+E  +  Q+   R    +  + + +  
Sbjct: 277 QLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERRE 336

Query: 152 PDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQRD 187
              R E+    R +  L++     ++ + +  +Q +
Sbjct: 337 QQLRREQE--ERREQQLRREQEEERREQQLRREQEE 370



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 36/151 (23%), Positives = 84/151 (55%), Gaps = 12/151 (7%)

Query: 4    ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPK---DDIKLTAKKE---VSKAPEDKK 57
            ER +    EE+      +E+   E      +ER +   ++ +L  ++E   + +   D+K
Sbjct: 1427 ERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRK 1486

Query: 58   KRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKK---QEEQAKRQQE 114
               E+ + ++++++RK +++E ++++E  +K  EEE++ H+++ ++K   +E+Q +RQ+ 
Sbjct: 1487 FLEEEQQLRRQERDRKFREQE-LRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQER 1545

Query: 115  EEAAAQMKEKE--ESIQLHQEAWERHHLRKE 143
             +   Q ++++  E  QL QE  E+   R+E
Sbjct: 1546 GQQRRQDRDRKFREEEQLRQEREEQQLSRQE 1576



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 31/147 (21%), Positives = 74/147 (50%), Gaps = 6/147 (4%)

Query: 5    RKKPASMEEKDSLPNNKEK----DCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
            +++     E++ L   K K    D  +R  +  +  P+ +  +   K   K  E+++ R 
Sbjct: 1193 QERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQ 1252

Query: 61   EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 120
             +D + ++   + ++D + +  E++ + +E+E ++  Q +    +EEQ +R++++EA  +
Sbjct: 1253 LEDSQLRD--RQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRR 1310

Query: 121  MKEKEESIQLHQEAWERHHLRKELRSK 147
             ++ +E  QL +E  E    R+E   K
Sbjct: 1311 DRKSQEEKQLLREEREEKRRRQETDRK 1337



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 35/163 (21%), Positives = 81/163 (49%), Gaps = 16/163 (9%)

Query: 12   EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKK-RLEDDKRKKEDK 70
            E ++   + +E+D   R       R + + K    ++  +  E +++ R E D++ +ED+
Sbjct: 1566 EREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDE 1625

Query: 71   E-----------RKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAA 119
            +           R+++D + ++ E + +++E E++ +H  + + ++EEQ  ++ EE+   
Sbjct: 1626 QLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLR 1685

Query: 120  QM----KEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEE 158
            +     K +EE  QL ++  ER  L++E + + Q       EE
Sbjct: 1686 RQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREE 1728



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 32/126 (25%), Positives = 67/126 (53%), Gaps = 14/126 (11%)

Query: 5    RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPE-DKKKRLEDD 63
            +++     E++ L   +E+     +    K R ++ ++   +++  +  + D K R E++
Sbjct: 1767 QERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEE 1826

Query: 64   KRKKEDKERKKKDE-------EKVKAEEESKKKE------EEEKKKHQEEERKKQEEQAK 110
            + + E++E++ + E       E+  A +E  ++E      EEE+K+ QE ERK +EE  +
Sbjct: 1827 QLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIR 1886

Query: 111  RQQEEE 116
            RQQ+EE
Sbjct: 1887 RQQKEE 1892



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 35/123 (28%), Positives = 61/123 (49%), Gaps = 6/123 (4%)

Query: 44  TAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERK 103
           T   E  +A  D K+ L  D+R++ED+ R +  + ++   EE   +   +K++ QE E  
Sbjct: 93  TGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQL---EEEPGQRRRQKRQEQERELA 149

Query: 104 KQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKE---LRSKNQNAPDSRPEENF 160
           + EEQ+++Q+  E   + +  EE  +  QE  ER   R E   L+S   +  +  P+E  
Sbjct: 150 EGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQ 209

Query: 161 FSR 163
             R
Sbjct: 210 LRR 212



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 43/219 (19%), Positives = 94/219 (42%), Gaps = 39/219 (17%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDI---------KLTAKKEVSKAPE 54
           +R+      ++      +E+   E +  S K    ++          +L   +   +  +
Sbjct: 167 QRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEK 226

Query: 55  DKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEE--------------------- 93
            +++R   D+  +E++E++ +  E V  +EE K +EEE                      
Sbjct: 227 QQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQEL 286

Query: 94  KKKHQEEERKKQ----EEQAKRQQEEEAAAQMKEKEESIQLHQEAWER--HHLRKELRSK 147
           +++ QEEE+++Q    E+Q +R+QEEE   Q +E+ E  +  ++  ER    LR+E   +
Sbjct: 287 RRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEER 346

Query: 148 NQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQR 186
            +       EE    R +  L++     ++ + +  +Q+
Sbjct: 347 REQQLRREQEE---ERREQQLRREQEEERREQQLRREQQ 382



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 37/177 (20%), Positives = 87/177 (49%), Gaps = 2/177 (1%)

Query: 21  KEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKV 80
           +E++ +E     ++ER K  I     +  S+A + ++ ++    RK+E + R+++ EEK 
Sbjct: 681 REQELAEEEQEQARERIKSRIPKWQWQLESEA-DARQSKVYSRPRKQEGQRRRQEQEEKR 739

Query: 81  KAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHL 140
           +  E   + +EEE+   Q++E +++ +   + Q EE + + +++  +    +E  ER   
Sbjct: 740 RRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLR 799

Query: 141 RKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQR-DSLSHDFNGL 196
            +E + + Q       E+    R     +K   F+++ + +  ++R   L  + +GL
Sbjct: 800 AEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGL 856



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 33/163 (20%), Positives = 82/163 (50%), Gaps = 5/163 (3%)

Query: 34   KERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE--RKKKDEEKVKAEEESKKKEE 91
            +ER +  +    +    +  E K +R E +++  ED++  R+++ +++++ E + K +E+
Sbjct: 1565 QEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFRED 1624

Query: 92   EEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNA 151
            E+  + +EE++  ++E+ ++  EEE   + +E+E+  QL  +   +    ++L  + +  
Sbjct: 1625 EQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQ--QLRHDRDRKFREEEQLLQEGEEQ 1682

Query: 152  PDSRPE-ENFFSRLDSSLKKNTAFVKKLKTITEQQRDSLSHDF 193
               R E +  F   +  L++     K L+   + +R  L   F
Sbjct: 1683 QLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKF 1725



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 34/143 (23%), Positives = 71/143 (49%), Gaps = 4/143 (2%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
           +++    EEK     ++ +   E R    ++  +     T + +  +  E  ++RL    
Sbjct: 729 QRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARP 788

Query: 65  RKKEDKERKKKDEEKVKAEEESKKKEEE-EKKKHQEEERKKQ---EEQAKRQQEEEAAAQ 120
             +E +ER+ + EE+ + E+    +EEE E+++ Q  ER+K+    E+ ++ Q  E A Q
Sbjct: 789 PLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQ 848

Query: 121 MKEKEESIQLHQEAWERHHLRKE 143
           ++E+E+ +Q  QE       R++
Sbjct: 849 LQEEEDGLQEDQERRRSQEQRRD 871



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 36/195 (18%), Positives = 91/195 (46%), Gaps = 16/195 (8%)

Query: 12   EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE 71
            E ++   + +E+D           R + D K   ++  S+ PE K    E    +++ + 
Sbjct: 1472 EREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQR 1531

Query: 72   RKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLH 131
            +  ++E++++ +E  +++ ++  +K +EEE+ +QE + ++   +E   + + +E+ ++  
Sbjct: 1532 KFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQ 1591

Query: 132  QEAWERHHLRKELRSKNQNAPDS-RPEENFFSRLDSSL------------KKNTAFVKKL 178
            ++  ER  +  E + + Q      R E +   R D  L            +++  F+++ 
Sbjct: 1592 EQ--ERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEE 1649

Query: 179  KTITEQQRD-SLSHD 192
              +  Q+R+  L HD
Sbjct: 1650 PQLRRQEREQQLRHD 1664



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 25/114 (21%), Positives = 63/114 (55%), Gaps = 5/114 (4%)

Query: 12   EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDK- 70
            +E D     +E+   ER     + + +D      ++++    ++++ R E D++ + ++ 
Sbjct: 1791 QESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQ 1850

Query: 71   ----ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 120
                E+ +++E+++  EEE K+++E E+K  +E  R++Q+E+ + +Q  E  +Q
Sbjct: 1851 FATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQ 1904



 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 30/185 (16%), Positives = 90/185 (48%), Gaps = 5/185 (2%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
           E++     EE+      + ++  ERR    + R +   +   ++   +   ++++   + 
Sbjct: 303 EQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQ 362

Query: 64  KRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKE 123
           + ++E +E ++  E++++ E++ +++++  +++    E++ + EQ  R++++    Q   
Sbjct: 363 QLRREQEEERR--EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420

Query: 124 KEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKK--LKTI 181
           +E+ ++  QE  ERH  + E   + Q     + E   + + +   +++    +K  LK  
Sbjct: 421 REQQLRREQEE-ERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRD 479

Query: 182 TEQQR 186
            E++R
Sbjct: 480 QEEER 484



 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 37/161 (22%), Positives = 82/161 (50%), Gaps = 19/161 (11%)

Query: 36   RPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERK-KKDEEKVKAEEESKKKEEEEK 94
            + +  ++   +++  +   D+K R E+ +  +++++RK +++E++V+ +E  +K  EEE+
Sbjct: 1394 KEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQ 1453

Query: 95   KKHQEEE--RKKQEEQAKRQQEEEAAAQMKEK-----EESIQLHQEAWERHHLRKELRSK 147
            +    +E  RK +EE+   Q+ EE     +E+     EE  QL ++  +R    +ELRS+
Sbjct: 1454 QL--RQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQ 1511

Query: 148  NQNAPDSRPEENFFSRLDS--SLKKNTAFVKKLKTITEQQR 186
                    PE  F          ++   F+++ + +  Q+R
Sbjct: 1512 -------EPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQER 1545



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 39/174 (22%), Positives = 88/174 (50%), Gaps = 20/174 (11%)

Query: 4    ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPK---DDIKLTAKKE---VSKAPEDKK 57
            E+K     +E+  + + ++    E +    +ER +   +D +L  ++E   + +   D+K
Sbjct: 1585 EQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRK 1644

Query: 58   KRLEDDKRKKE--------DKERKKKDEEKV--KAEEESKKKEEEEKKKHQEEERKKQEE 107
               E+ + +++        D++RK ++EE++  + EE+  +++E ++K  +EE++ +++E
Sbjct: 1645 FLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQE 1704

Query: 108  QAKRQQEEEAAAQMKEKE----ESIQLHQEAWERHHLRKELRSKNQNAPDSRPE 157
            + ++  +EE   + +E E    E  QL QE  +    R+E   K       RPE
Sbjct: 1705 RERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPE 1758



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 33/193 (17%), Positives = 92/193 (47%), Gaps = 10/193 (5%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAP---EDKKKRLE 61
           R++ + ++ ++    ++++   E+R   + +   ++     ++ +S  P   E ++++L 
Sbjct: 740 RRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLR 799

Query: 62  DDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQM 121
            ++R++ ++    ++EEK +   + +++E+E +   +EE+ +++E   + Q+EE+   + 
Sbjct: 800 AEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQED 859

Query: 122 KEKEES-IQLHQEAW------ERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAF 174
           +E+  S  Q   + W      ER   R  L +K       R E+      +  L++    
Sbjct: 860 QERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREERE 919

Query: 175 VKKLKTITEQQRD 187
            ++ +    Q R+
Sbjct: 920 KRRRQEQERQYRE 932



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 39/167 (23%), Positives = 84/167 (50%), Gaps = 20/167 (11%)

Query: 3   AERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL-- 60
           A R++    + +D     + ++ SER       RP     L  ++E     E++++R   
Sbjct: 754 AHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPP----LREQRERQLRAEERQQREQR 809

Query: 61  ---EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEA 117
              E++++++  ++R+++++E    EEE + +  E  ++ QEEE   QE+Q +R++ +E 
Sbjct: 810 FLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQ-ERRRSQE- 867

Query: 118 AAQMKEKEESIQLHQEAWERHH-------LRKELRSKNQNAPDSRPE 157
             Q ++++   QL +E   R H       L+++LR + Q   +   E
Sbjct: 868 --QRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEE 912



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 25/107 (23%), Positives = 60/107 (56%), Gaps = 6/107 (5%)

Query: 13   EKDSLPNNKEKDCSERRTVSSKER-PKDDIKLTAKKEVSKAPEDKKKRLED-----DKRK 66
            E++ L   +E+     +    K R  ++ ++L  +++  +   D++ R E+     +K +
Sbjct: 1799 EEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSR 1858

Query: 67   KEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQ 113
            +E++E  +++E+K + E E K +EE  +++ +EE+R +Q  + K Q+
Sbjct: 1859 REEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQE 1905



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 36/180 (20%), Positives = 78/180 (43%), Gaps = 24/180 (13%)

Query: 10  SMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKED 69
           ++ +   L   K   C  + ++    R ++D          +  E + ++LE++  ++  
Sbjct: 88  ALGQATGLDEEKRARCDGKESLLQDRRQEED---------QRRFEPRDRQLEEEPGQRRR 138

Query: 70  KERKKKDEEKVKAEEESKKKEEEEKKKHQE---------EERKKQEEQAKRQQEEEAAAQ 120
           ++R++++ E  + EE+S+K+E  E++  Q          +E +++EE   R+ EEE    
Sbjct: 139 QKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREE---RRAEEEQLQS 195

Query: 121 MKEKEESIQLHQEAWERH---HLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKK 177
            K  E      +E   R     LR++ R + Q     R +  F    +   +K    ++K
Sbjct: 196 CKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRK 255



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 39/181 (21%), Positives = 86/181 (47%), Gaps = 33/181 (18%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDI-------KLTAKKEVSKAPE-- 54
           + +K A  + K+SL  ++ ++  +RR      + +++        +   ++E+++  E  
Sbjct: 96  DEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQS 155

Query: 55  DKKKRLEDDKRKKEDKE-----RKKKDEEKVKAEEESKKK-----------EEEEKKKHQ 98
           +K++RLE   R++ D+E     ++ ++ E+ +AEEE  +            EE+ +++  
Sbjct: 156 EKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRREL 215

Query: 99  EEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHH--LRKELRSKNQNAPDSRP 156
            E R+K  E+ ++Q+ E      +E+EE      + W +    LRKE     +  P  + 
Sbjct: 216 LELRRKGREEKQQQRRERQDRVFQEEEE------KEWRKRETVLRKEEEKLQEEEPQRQR 269

Query: 157 E 157
           E
Sbjct: 270 E 270



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 30/203 (14%), Positives = 98/203 (48%), Gaps = 22/203 (10%)

Query: 4    ERKKPASMEEKDSLPNNKEKDCSERRTVSSK--ERPKDDIKLTAKKEVSKAPEDKKKRLE 61
            ER+K    E +      +E    E + +  +  +R + +++   ++E     E+++   E
Sbjct: 1127 EREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLRE 1186

Query: 62   DDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKR---------- 111
            + +++++++ER+ ++EE+++ ++  ++  +E+++   + + + ++E A R          
Sbjct: 1187 EQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRE 1246

Query: 112  ----QQEEEAAAQMKEKEESIQL---HQEAWERHHLRKELRSKNQNAPDSRPEENFFSRL 164
                +Q E++  + ++ ++ +Q     Q+  +R   R+  + ++++ P+   EE      
Sbjct: 1247 NEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPE---EEQLEREE 1303

Query: 165  DSSLKKNTAFVKKLKTITEQQRD 187
                K+     ++ K +  ++R+
Sbjct: 1304 QKEAKRRDRKSQEEKQLLREERE 1326



 Score = 39.7 bits (91), Expect = 0.019
 Identities = 33/193 (17%), Positives = 90/193 (46%), Gaps = 11/193 (5%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
           E +  A   +  S P  +E     +     + R + +++   ++   +  +++++R  D 
Sbjct: 709 ESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQR-RDF 767

Query: 64  KRKKEDKERKKKDEEKVKAE---EESKKKEEEEKKKHQEEER----KKQEEQAKRQ-QEE 115
             + + +E+ ++  +++ A     E ++++   +++ Q E+R    ++++EQ +RQ +E 
Sbjct: 768 TWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRER 827

Query: 116 EAAAQMKEKEESIQLHQEAWERHHLRKELR--SKNQNAPDSRPEENFFSRLDSSLKKNTA 173
           E   Q  E+EE +Q  + A +       L+   + + + + R ++ +  +L+   K+   
Sbjct: 828 EKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRH 887

Query: 174 FVKKLKTITEQQR 186
            +     + EQ R
Sbjct: 888 TLYAKPALQEQLR 900



 Score = 37.4 bits (85), Expect = 0.092
 Identities = 49/239 (20%), Positives = 96/239 (40%), Gaps = 6/239 (2%)

Query: 993  LEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEV 1052
            L+E   Q++ LER+ L +     ++  +  +   + L   +EEE    E +E+   + E 
Sbjct: 271  LQEEEEQLRKLERQEL-RRERQEEEQQQQRLRREQQLRRKQEEER--REQQEERREQQER 327

Query: 1053 NEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTEVMIKGGGLKHVPCVEDED 1112
             E +EE        E EE  E+      +  +  +      E   +   L+    +  E 
Sbjct: 328  REQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQ 387

Query: 1113 FIQALDKMMLENLQQRSGESVKVHQLDVAIPLHLKSQLRKGPPLGGGEGEAESADTMPFV 1172
             ++   ++  E   +R  +  +  QL     L  + QLR+       E + E        
Sbjct: 388  QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQ-- 445

Query: 1173 MLTRKGNKQQFKILNVPMSSQLAANHWNQQ-QAEQEERMRMKKLTLDINERQEQEDYQE 1230
             L R+  +++  +     + +       QQ + +QEE  R + L L+  ER+EQ++ +E
Sbjct: 446  RLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERRE 504



 Score = 36.2 bits (82), Expect = 0.21
 Identities = 44/235 (18%), Positives = 92/235 (39%), Gaps = 18/235 (7%)

Query: 1018 DSKDSMTEGENLEEDE----------EEEEGGAETEEQSGNESEVNEPEE----EEGSDN 1063
            D K+S+ +    EED+          EEE G    +++   E E+ E EE    +E  + 
Sbjct: 104  DGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQ 163

Query: 1064 DDDEGEEEEEENTDYLTDSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLE 1123
             D +  +EE           +E   +EE  +   KG   +  P   DE+ ++  + + L 
Sbjct: 164  RDRQRRDEELWRQRQEWQEREERRAEEEQLQ-SCKGHETEEFP---DEEQLRRRELLELR 219

Query: 1124 NLQQRSGESVKVHQLDVAIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQF 1183
               +   +  +  + D       + + RK   +   E E    +        ++  +Q  
Sbjct: 220  RKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLR 279

Query: 1184 KILNVPMSSQLAANHWNQQQAEQEERMRMKKLTLDINERQEQEDYQEMLQSLAQR 1238
            K+    +  +       QQ+  +E+++R K+      +++E+ + QE  +   +R
Sbjct: 280  KLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEER 334



 Score = 35.4 bits (80), Expect = 0.35
 Identities = 33/146 (22%), Positives = 63/146 (43%), Gaps = 20/146 (13%)

Query: 994  EESIRQVQDLEREFLIKLGLVNDKDSK-DSMTEGENLEEDE----EEEEGGAETEEQSGN 1048
            E   R+ Q+ ER++  K  L  +++       E   L+E E    EEEE   E E+  G 
Sbjct: 1007 EREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGE 1066

Query: 1049 ESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTEVMIKGGGLKHVPCV 1108
            E E    +E E     ++E ++EEE+      +  +  E + +               C 
Sbjct: 1067 ERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQ---------------CR 1111

Query: 1109 EDEDFIQALDKMMLENLQQRSGESVK 1134
            E+E+  Q  ++++ E  ++R  + ++
Sbjct: 1112 EEEELQQEEEQLLREEREKRRRQELE 1137



 Score = 35.4 bits (80), Expect = 0.35
 Identities = 34/141 (24%), Positives = 60/141 (42%), Gaps = 5/141 (3%)

Query: 993  LEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEED--EEEEEGGAETEEQSGNES 1050
            LE   R+ +++++E    L    +K  +  +      EE+  +EEE+   E +E+   E 
Sbjct: 1136 LERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQER 1195

Query: 1051 EVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTEVMIKGGGLKHVPCVED 1110
            E    EEEE       +   +E++ +D       E E    + +V  KG   +    +ED
Sbjct: 1196 ERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLED 1255

Query: 1111 EDFIQALDKMMLENLQQRSGE 1131
                Q  D+   ++LQ   GE
Sbjct: 1256 S---QLRDRQSQQDLQHLLGE 1273



 Score = 34.7 bits (78), Expect = 0.60
 Identities = 24/102 (23%), Positives = 46/102 (45%), Gaps = 11/102 (10%)

Query: 995  ESIRQVQDLEREFLIKLGLVNDKDSKDSMTE--GENLEEDEEEEEGGAETEEQSGNESEV 1052
            E  RQ++D +         + D+ S+  +    GE  E D E+E    +  ++   E E 
Sbjct: 1248 EQFRQLEDSQ---------LRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQ 1298

Query: 1053 NEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTE 1094
             E EE++ +   D + +EE++   +   +  +  ETD +  E
Sbjct: 1299 LEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFRE 1340



 Score = 34.7 bits (78), Expect = 0.60
 Identities = 54/275 (19%), Positives = 105/275 (38%), Gaps = 18/275 (6%)

Query: 990  CNSLEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNE 1049
            C   E+ +RQ  D +R+F  +   ++ ++      E E     +E E    E E+Q   E
Sbjct: 1401 CQEREQQLRQ--DRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQE 1458

Query: 1050 SEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSN--KENETDEENTEVMIKGGGLKHVPC 1107
                  EEE+     +++    +E +  +L +    +  E D +  E  ++    +    
Sbjct: 1459 RHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFL 1518

Query: 1108 VEDEDF--IQALDKMMLENLQQRSGESVKVHQLDVAIPLHLKSQLRKGPPLGGGEGEAES 1165
             E++     Q   K + E  Q R  E  +  + D       + QLR+       E E + 
Sbjct: 1519 EEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQ-------EREEQQ 1571

Query: 1166 ADTM----PFVMLTRKGNKQQFKILNVPMSSQLAANHWNQQQAEQEERMRMKKLTLDINE 1221
                     F +  +K  +Q+ +   +    QL      QQQ  QE   + ++    + E
Sbjct: 1572 LSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQE-GQQQLRQERDRKFREDEQLLQE 1630

Query: 1222 RQEQEDYQEMLQSLAQRPAPANTNRERRPRYQHPK 1256
            R+EQ+ +++          P    +ER  + +H +
Sbjct: 1631 REEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDR 1665



 Score = 33.9 bits (76), Expect = 1.0
 Identities = 53/270 (19%), Positives = 108/270 (40%), Gaps = 21/270 (7%)

Query: 999  QVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEE 1058
            Q+Q  E + L +      +  ++     +   + +EE+  G E E++   E E    EEE
Sbjct: 935  QLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEE 994

Query: 1059 EGSDNDDD--EGEEEEEENTDYLTDSNKENETDEENTEVMIKGGGLKHVPCVE----DED 1112
            E    ++     E E+    ++     K++E  +E  +++ +    + +   E    +E+
Sbjct: 995  ELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEE 1054

Query: 1113 FIQALDKMML--ENLQQRSGESVKVHQLDVAIPLHLKSQLRKGPPLGGGE------GEAE 1164
             +Q  ++ +L  E   +R  E  + ++ +  +    +  LR+ P     +       E E
Sbjct: 1055 ELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEE 1114

Query: 1165 SADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWNQQQAEQ---EERMRMKKLTLDINE 1221
                    +L  +  K++       +  Q       QQ+ EQ   EE  + ++  L+   
Sbjct: 1115 ELQQEEEQLLREEREKRR----RQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQY 1170

Query: 1222 RQEQEDYQEMLQSLAQRPAPANTNRERRPR 1251
            R+E+E  QE  Q L +        RER+ R
Sbjct: 1171 REEEELQQEEEQLLREEQEKRRQERERQYR 1200



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 60/321 (18%), Positives = 124/321 (38%), Gaps = 47/321 (14%)

Query: 956  KKSLEVWTKDHPFPIDIDYMISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVN 1015
            K+  + W + +    ++       L   R K +L    E   R+ ++L++E    LG   
Sbjct: 1010 KRRRQEWERQYRKKDELQQEEEQLLREEREKRRL-QERERQYREEEELQQEEEQLLG--- 1065

Query: 1016 DKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEEN 1075
              + +++    E   +  +EEE   E E+    E E    +E E    +++E ++EEE+ 
Sbjct: 1066 --EERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQL 1123

Query: 1076 TDYLTDSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKV 1135
                 +  +  E + +  E        + V   E++   +  +K   + L+++  E  ++
Sbjct: 1124 LREEREKRRRQELERQYREE-------EEVQQEEEQLLREEPEKRRRQELERQYREEEEL 1176

Query: 1136 HQLDVAIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLA 1195
             Q +  +    + + R+       E E           L R+  KQ+++        Q +
Sbjct: 1177 QQEEEQLLREEQEKRRQERERQYREEEE----------LQRQKRKQRYR-----DEDQRS 1221

Query: 1196 ANHWNQQQAEQEERMRMKKL--------------TLDINERQEQEDYQEMLQSLAQRPAP 1241
               W Q + E+E  +R  K+                 + +RQ Q+D Q +L    +R   
Sbjct: 1222 DLKW-QWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQER--- 1277

Query: 1242 ANTNRERRPRYQHPKGAPNAD 1262
             +  +ERR   Q  +  P  +
Sbjct: 1278 -DREQERRRWQQRDRHFPEEE 1297



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 64/302 (21%), Positives = 115/302 (38%), Gaps = 50/302 (16%)

Query: 994  EESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVN 1053
            E+ +R+ Q+  RE  +K     ++  +   +E +   E EE  E   + EE+   E E  
Sbjct: 504  EQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERR 563

Query: 1054 EP----EEEEGSD----NDDDEGE-----EEEEENTDYLTDSNKENETDEENTEVMIK-- 1098
            E     E+EE  D     +++  +     E+EE     L     E    EE  E  +K  
Sbjct: 564  EQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKRE 623

Query: 1099 -GGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDVAIPLHLK---SQLRKGP 1154
                 +    ++ E+  +   + +    Q+R  + +K  + +  +   LK    + R+  
Sbjct: 624  EPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQ 683

Query: 1155 PLGGGEGEAESADTMPFV-----MLTRKGNKQQFKILNVPMSSQLAANHWNQQQAEQEER 1209
             L   E E         +      L  + + +Q K+ + P   +       +++ EQEE+
Sbjct: 684  ELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQE-----GQRRRQEQEEK 738

Query: 1210 MRMKKLTLDINE-----RQEQEDYQEM---------------LQSLAQRPAPANTNRERR 1249
             R ++  L   E     RQ+QE+ Q                  Q L+ RP P    RER+
Sbjct: 739  RRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARP-PLREQRERQ 797

Query: 1250 PR 1251
             R
Sbjct: 798  LR 799



 Score = 30.8 bits (68), Expect = 8.6
 Identities = 55/282 (19%), Positives = 110/282 (39%), Gaps = 17/282 (6%)

Query: 981  ELLRPKIKLCNSLEESIRQVQDL------EREFLIKLGLVNDKDSKDSMTEGENLEEDEE 1034
            ELL  + K     ++  R+ QD       E+E+  +  ++  ++ K    E +   E +E
Sbjct: 214  ELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQE 273

Query: 1035 EEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTE 1094
            EEE   + E Q        E ++++    +     ++EEE  +   +  ++ E  E+  E
Sbjct: 274  EEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEE 333

Query: 1095 VMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDVAIPLHLKSQLRKGP 1154
               +    +     E +   +  ++   + L++   E  +  QL     L  + QLR+  
Sbjct: 334  RREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQ 393

Query: 1155 PLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWNQQQAEQEERMRMKK 1214
             L   +             L R   +QQ +        Q    H  +Q+ EQE   R ++
Sbjct: 394  QLRREQQLRREQQLRREQQLRR---EQQLRREQQLRREQEEERH--EQKHEQER--REQR 446

Query: 1215 LTLDINERQE----QEDYQEMLQSLAQRPAPANTNRERRPRY 1252
            L  +  ER++    +E+ +   Q   ++    +   ERR R+
Sbjct: 447  LKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERW 488



 Score = 30.8 bits (68), Expect = 8.6
 Identities = 24/105 (22%), Positives = 46/105 (43%), Gaps = 3/105 (2%)

Query: 993  LEESIR--QVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNES 1050
            LE+ ++  +V+ LE+E   +  L  ++  ++   +    EE EE  +     E+Q   E 
Sbjct: 598  LEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQ 657

Query: 1051 EVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTEV 1095
             +   EEEE  +    + E EEE     L +  +E   +   + +
Sbjct: 658  RLKREEEEERLE-QRLKREHEEERREQELAEEEQEQARERIKSRI 701


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 72.0 bits (175), Expect = 3e-12
 Identities = 40/149 (26%), Positives = 82/149 (55%), Gaps = 12/149 (8%)

Query: 11  MEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKE-- 68
           M E+  LP  KEK     +    ++  + + K+  ++++ K  ++++K+  D ++ +E  
Sbjct: 654 MWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEE 713

Query: 69  ---DKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQE----EQAKRQQEEEAAAQM 121
              ++E+K ++EE++  E+E K +E+EEK + QEEE  +QE    EQ ++  E++   + 
Sbjct: 714 SMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQ 773

Query: 122 KEK---EESIQLHQEAWERHHLRKELRSK 147
           KEK    E +Q  ++ WE+    ++   K
Sbjct: 774 KEKLWEHEKMQEQEKIWEQEEKMRDQEEK 802



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 42/138 (30%), Positives = 82/138 (59%), Gaps = 12/138 (8%)

Query: 12  EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK--RKKED 69
           E+++ +   +EK   ++R    KE+  +  K+   +E  K  E ++K  E +K  +K ++
Sbjct: 642 EQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKM---QEQEKMQEQEEKIWEQEKMEKKTQE 698

Query: 70  KERKKKDEEKVKAEE---ESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEE 126
           +E+K  D+EK++ EE   E +KK  EE++  +E+E K QE++ K Q++EE   +M E+EE
Sbjct: 699 QEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEE---EMWEQEE 755

Query: 127 SI-QLHQEAWERHHLRKE 143
            + +  ++ WE+  L ++
Sbjct: 756 KMWEQEEKMWEQQRLPEQ 773



 Score = 63.9 bits (154), Expect = 9e-10
 Identities = 47/204 (23%), Positives = 98/204 (48%), Gaps = 14/204 (6%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
           R++    E++  +   +EK   +   +  +E    + +    ++  +  E +K+  E +K
Sbjct: 276 RQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEK 335

Query: 65  RKKEDKERKKKDEEKVKAEE-----ESKKKEEEEKKKHQEE---ERKKQ---EEQAKRQQ 113
             +E KE ++++E+  + EE     E K +E+EEK   QEE   E++KQ   +EQ  R Q
Sbjct: 336 ELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQ 395

Query: 114 EE---EAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKK 170
           EE   E   +++EKEE ++  ++ WE+    +E +   +    +R +E      +   ++
Sbjct: 396 EERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIRER 455

Query: 171 NTAFVKKLKTITEQQRDSLSHDFN 194
                ++ +T+ EQ+      + N
Sbjct: 456 EKKMREEEETMREQEEKMQKQEEN 479



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 39/135 (28%), Positives = 79/135 (58%), Gaps = 12/135 (8%)

Query: 11  MEEKDSLPNNKEKDCSER--RTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKE 68
           M E++    ++E+   E+  R    +ER ++  K+   ++V K  E+KK  +++ ++K  
Sbjct: 385 MREQEQKMRDQEERMWEQDERLREKEERMREQEKMW--EQVEKMREEKK--MQEQEKKTR 440

Query: 69  DKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESI 128
           D+E K ++EE+++ E E K +EEEE  + QEE+ +KQEE    Q+E+E   Q   +++  
Sbjct: 441 DQEEKMQEEERIR-EREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQK-- 497

Query: 129 QLHQEAWERHHLRKE 143
              ++ WE+  ++++
Sbjct: 498 ---EKLWEQEKMQEQ 509



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 46/195 (23%), Positives = 94/195 (48%), Gaps = 18/195 (9%)

Query: 12  EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAK-KEVSKAPEDKKKRLEDDKRKKEDK 70
           EEK      K  D  ER    ++E+ K       K +E  +  E +KK  E+++  +E +
Sbjct: 550 EEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE 609

Query: 71  ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ---------- 120
           E+ ++ EEK++ E+E K  E+EEK + QEE+  +QEE+   Q+E+    Q          
Sbjct: 610 EKMQEQEEKMQ-EQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLW 668

Query: 121 ----MKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRP--EENFFSRLDSSLKKNTAF 174
               M+E+E+  +  ++ WE+  + K+ + + +   D     EE      +  +++    
Sbjct: 669 EHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEM 728

Query: 175 VKKLKTITEQQRDSL 189
           +++ +   ++Q + +
Sbjct: 729 MREQEEKMQEQEEKM 743



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 39/176 (22%), Positives = 91/176 (51%), Gaps = 11/176 (6%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
           ER +  + E++    + +EK   E R    +++ +++ ++  ++E  K  E ++K  E +
Sbjct: 565 ERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE-EKMQEQEEKMQEQE 623

Query: 64  KRKKEDKERKKKDEEKVKAEEESKKKEEE---------EKKKHQEEERKKQEEQAKRQQE 114
           ++  E +E+ ++ EEK+  +EE   ++EE         E+K+   E  K QE++  ++QE
Sbjct: 624 EKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQE 683

Query: 115 EEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKK 170
           E+   Q K ++++ +  ++ W++  +R+E  S  +     R EE      +  +++
Sbjct: 684 EKIWEQEKMEKKTQEQEKKTWDQEKMREE-ESMREREKKMREEEEMMREQEEKMQE 738



 Score = 60.8 bits (146), Expect = 8e-09
 Identities = 39/133 (29%), Positives = 82/133 (61%), Gaps = 11/133 (8%)

Query: 12  EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE 71
           E++D +   +EK   + + +  +E   +  K T ++E  K   D+++++ +++R +E +E
Sbjct: 541 EQEDQMWEQEEKMRDQEQKMWDQEERME--KKTQEQE--KKTWDQEEKMREEERMRE-RE 595

Query: 72  RKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESI-QL 130
           +K ++EE++  E+E K +E+EEK   QE+E K  E++ K Q++EE   +M E+EE + + 
Sbjct: 596 KKMREEEEMMREQEEKMQEQEEK--MQEQEEKMWEQEEKMQEQEE---KMWEQEEKMWEQ 650

Query: 131 HQEAWERHHLRKE 143
            ++ WE+  L ++
Sbjct: 651 EEKMWEQQRLPEQ 663



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 42/154 (27%), Positives = 82/154 (53%), Gaps = 18/154 (11%)

Query: 12  EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE 71
           E+++ +   +EK   +   +  +E    + +   +++  K  + +++  E D+R +E +E
Sbjct: 352 EQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEE 411

Query: 72  RKKKDE---EKVKAEEESKKKEEEEKK------KHQEEERKKQEEQAKRQQEEEAAAQMK 122
           R ++ E   E+V+   E KK +E+EKK      K QEEER ++ E+  R++EE     M+
Sbjct: 412 RMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEE----TMR 467

Query: 123 EKEESIQLHQE-AWERHHLRKELRSKNQNAPDSR 155
           E+EE +Q  +E  WE    ++E   + Q  P+ +
Sbjct: 468 EQEEKMQKQEENMWE----QEEKEWQQQRLPEQK 497



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 39/151 (25%), Positives = 79/151 (52%), Gaps = 8/151 (5%)

Query: 1   MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
           +P +++K   + E++ +   +EK   +   +  +E      K   ++E  +  ED+    
Sbjct: 493 LPEQKEK---LWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ 549

Query: 61  EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE---EA 117
           E+  R +E K   +++  + K +E+ KK  ++E+K  +EEER ++ E+  R++EE   E 
Sbjct: 550 EEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKM-REEERMREREKKMREEEEMMREQ 608

Query: 118 AAQMKEKEESIQLHQE-AWERHHLRKELRSK 147
             +M+E+EE +Q  +E  WE+    +E   K
Sbjct: 609 EEKMQEQEEKMQEQEEKMWEQEEKMQEQEEK 639



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 37/150 (24%), Positives = 78/150 (52%), Gaps = 6/150 (4%)

Query: 12  EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE 71
           E+++ + + +E    E++    ++  + + ++  ++E  +  E K    E+   KK  ++
Sbjct: 515 EQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQ 574

Query: 72  RKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQE--EEAAAQMKEKEESIQ 129
            KK  +++ K  EE + +E E+K + +EE  ++QEE+ + Q+E  +E   +M E+EE +Q
Sbjct: 575 EKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQ 634

Query: 130 LHQE-AWERHHLRKELRSK---NQNAPDSR 155
             +E  WE+     E   K    Q  P+ +
Sbjct: 635 EQEEKMWEQEEKMWEQEEKMWEQQRLPEQK 664



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 41/200 (20%), Positives = 101/200 (50%), Gaps = 23/200 (11%)

Query: 6   KKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKR 65
           ++   M+E++    ++E+   E   +  +E+     K+  ++E  +  E+K ++ E++  
Sbjct: 427 REEKKMQEQEKKTRDQEEKMQEEERIREREK-----KMREEEETMREQEEKMQKQEENMW 481

Query: 66  KKEDKE--RKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEE-----------QAKRQ 112
           ++E+KE  +++  E+K K  E+ K +E+EEK   QEE+ + QEE           +  R+
Sbjct: 482 EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMRE 541

Query: 113 QEE---EAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLK 169
           QE+   E   +M+++E+ +   +E  E+    +E ++ +Q   +   EE      +  ++
Sbjct: 542 QEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQE--EKMREEERMREREKKMR 599

Query: 170 KNTAFVKKLKTITEQQRDSL 189
           +    +++ +   ++Q + +
Sbjct: 600 EEEEMMREQEEKMQEQEEKM 619



 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 40/184 (21%), Positives = 96/184 (52%), Gaps = 8/184 (4%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
           R+K   M E++ +    EK   E++    +++ +D  +   ++E  +  E +KK  E+++
Sbjct: 407 REKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEE--RIREREKKMREEEE 464

Query: 65  RKKEDKERKKKDEEKVKAEEESKKKEEE--EKKKHQEEERKKQEEQAKRQQEEEAAAQMK 122
             +E +E+ +K EE +  +EE + +++   E+K+   E+ K QE++ K  ++EE   +++
Sbjct: 465 TMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE---KIR 521

Query: 123 EKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTIT 182
           ++EE     ++ W +  +R++     +     R +E      +  ++K T   +K KT  
Sbjct: 522 DQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEK-KTWD 580

Query: 183 EQQR 186
           ++++
Sbjct: 581 QEEK 584



 Score = 57.8 bits (138), Expect = 7e-08
 Identities = 37/151 (24%), Positives = 80/151 (52%), Gaps = 7/151 (4%)

Query: 12  EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLED--DKRKKED 69
           ++++++   +EK+  ++R    KE+  +  K+  ++E     E+K +  E+   + KK  
Sbjct: 475 KQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMW 534

Query: 70  KERKKKDEEKVKAEEESKKKEEEEKKKHQEE--ERKKQEEQAKRQQEEEAAAQMKEKEES 127
           ++ K +++E    E+E K +++E+K   QEE  E+K QE++ K   +EE   +M+E+E  
Sbjct: 535 RQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEE---KMREEERM 591

Query: 128 IQLHQEAWERHHLRKELRSKNQNAPDSRPEE 158
            +  ++  E   + +E   K Q   +   E+
Sbjct: 592 REREKKMREEEEMMREQEEKMQEQEEKMQEQ 622



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 44/172 (25%), Positives = 85/172 (49%), Gaps = 26/172 (15%)

Query: 1   MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
           M  + +K    EEK      K ++  E+     ++  + + K+    E  + PE K+K  
Sbjct: 612 MQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMW---EQQRLPEQKEKLW 668

Query: 61  EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKK-------------HQEEERKKQEE 107
           E +K   +++E+ ++ EEK+  +E+ +KK +E++KK              + E++ ++EE
Sbjct: 669 EHEKM--QEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEE 726

Query: 108 QAKRQQEEEAAAQMKEKEESIQ-LHQEAWERHHLRKELRSK---NQNAPDSR 155
           +  R+QEE    +M+E+EE +Q   +E WE+     E   K    Q  P+ +
Sbjct: 727 EMMREQEE----KMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQK 774



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 40/185 (21%), Positives = 98/185 (52%), Gaps = 11/185 (5%)

Query: 11  MEEKDSLPNNKEKDCSERRTVSSKERP--KDDIKLTAKKEVSKAPEDK----KKRLEDDK 64
           + E++     +EK+  E++ +  +E    + + K+  ++E  +  E+K    ++RL + +
Sbjct: 323 LREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE 382

Query: 65  RKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQE---EERKKQEEQAKRQQEEEAAAQM 121
           ++  ++E+K +D+E+   E++ + +E+EE+ + QE   E+ +K  E+ K Q++E+     
Sbjct: 383 KQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQ 442

Query: 122 KEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTI 181
           +EK +  +  +E  E+    +E   + Q     + EEN + + +   ++     +K K +
Sbjct: 443 EEKMQEEERIRER-EKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK-L 500

Query: 182 TEQQR 186
            EQ++
Sbjct: 501 WEQEK 505



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 39/162 (24%), Positives = 81/162 (50%), Gaps = 15/162 (9%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
           R++   M E++ +   +E+   E+     ++  + + K+  ++E  +  E+K    E+  
Sbjct: 592 REREKKMREEEEMMREQEEKMQEQE----EKMQEQEEKMWEQEEKMQEQEEKMWEQEEKM 647

Query: 65  RKKEDK--------ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEE 116
            ++E+K        E+K+K  E  K +E+ K +E+EEK   QE+  KK +EQ K+  ++E
Sbjct: 648 WEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQE 707

Query: 117 AAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEE 158
              +M+E+E   +  ++  E   + +E   K Q   +   E+
Sbjct: 708 ---KMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQ 746



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 40/202 (19%), Positives = 102/202 (50%), Gaps = 20/202 (9%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
           R++    E+ + +   K+    E++T   +E+ +++ ++  +++  +  E+  +  E+  
Sbjct: 414 REQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKM 473

Query: 65  RKKEDK--ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQE-------- 114
           +K+E+   E+++K+ ++ +  E+ +K  E+EK + QEE+  +QEE+ + Q+E        
Sbjct: 474 QKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKM 533

Query: 115 ------EEAAAQMKEKEESIQ-LHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSS 167
                  E   QM E+EE ++   Q+ W++   R E +++ Q       EE    R +  
Sbjct: 534 WRQEKMREQEDQMWEQEEKMRDQEQKMWDQEE-RMEKKTQEQEKKTWDQEEKM--REEER 590

Query: 168 LKKNTAFVKKLKTITEQQRDSL 189
           +++    +++ + +  +Q + +
Sbjct: 591 MREREKKMREEEEMMREQEEKM 612



 Score = 54.3 bits (129), Expect = 7e-07
 Identities = 37/131 (28%), Positives = 72/131 (54%), Gaps = 13/131 (9%)

Query: 11  MEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDK 70
           M E+  LP  KEK     +    ++  + + K+  ++E  +  E+K +  E+  R +E+K
Sbjct: 764 MWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEK 823

Query: 71  -----ERKKKDEEKVKAEEES---KKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMK 122
                E+    EEK+  +EE    ++++ EEK + QEE+ ++QEE+ + Q+E     +M+
Sbjct: 824 MWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEE-----KMR 878

Query: 123 EKEESIQLHQE 133
           E+EE ++  +E
Sbjct: 879 EQEEKMRGQEE 889



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 36/138 (26%), Positives = 75/138 (54%), Gaps = 6/138 (4%)

Query: 1   MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDK---K 57
           M  E +     EEK      K ++  E+     ++  + + K+  ++E     E+K   +
Sbjct: 598 MREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQ 657

Query: 58  KRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQE--E 115
           +RL + K K  + E K +++EK++ +EE   ++E+ +KK QE+E+K  +++  R++E   
Sbjct: 658 QRLPEQKEKLWEHE-KMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMR 716

Query: 116 EAAAQMKEKEESIQLHQE 133
           E   +M+E+EE ++  +E
Sbjct: 717 EREKKMREEEEMMREQEE 734



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 38/139 (27%), Positives = 69/139 (49%), Gaps = 10/139 (7%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
           R++   M E++     +E+   E+     ++  K   +     E  + PE K+K  E +K
Sbjct: 723 REEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEK 782

Query: 65  RKKEDK----ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQ------QE 114
            ++++K    E K +D+E+    +E K + +EEK + QEE+   QEE+   Q      QE
Sbjct: 783 MQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQE 842

Query: 115 EEAAAQMKEKEESIQLHQE 133
           E+   Q ++ EE +Q  +E
Sbjct: 843 EKMWGQEEKMEEKMQGQEE 861



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 41/167 (24%), Positives = 82/167 (49%), Gaps = 40/167 (23%)

Query: 21  KEKDCSE----RRTVSSKERPKDDIKL--------TAKKEVSKAPEDKKKRL-------- 60
           KE+D       R T++++E  K + +L        + K E+    ++ K++L        
Sbjct: 204 KERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLP 263

Query: 61  --------------EDDKRKKEDKERKKKD----EEKVKAEEESKKKEEEEKKKHQEEER 102
                         E++ R++E K RK+++    +E+   E+E K +E+EEK   QE+  
Sbjct: 264 QVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRL 323

Query: 103 KKQEEQAKRQQEE-EAAAQMKEKEESIQLHQE-AWERHHLRKELRSK 147
           ++QE++ + Q++E     +++E+EE +Q  +E  WE+    +E   K
Sbjct: 324 REQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEK 370



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 34/122 (27%), Positives = 68/122 (55%), Gaps = 5/122 (4%)

Query: 12  EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE 71
           E+++ +   +EK   ++R    KE+  +  K+   +E  K  E ++K  + +++ +  +E
Sbjct: 752 EQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKM---QEQEKIWEQEEKMRDQEEKMRGQEE 808

Query: 72  RKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLH 131
           + +  EEK++ +EE K   +EEK   QEE+   QEE+    QEE+   +M+ +EE ++  
Sbjct: 809 KMRGQEEKMRGQEE-KMWGQEEKMWGQEEKMWGQEEK-MWGQEEKMEEKMQGQEEKMREQ 866

Query: 132 QE 133
           +E
Sbjct: 867 EE 868



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 40/160 (25%), Positives = 76/160 (47%), Gaps = 12/160 (7%)

Query: 11  MEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDK 70
           M E++S+   ++K   E   +  +E    + +   +++  +  E ++K  E +++  E +
Sbjct: 709 MREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQ 768

Query: 71  ---ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAK------RQQEEEAAAQ- 120
              E+K+K  E  K +E+ K  E+EEK + QEE+ + QEE+ +      R QEE+   Q 
Sbjct: 769 RLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQE 828

Query: 121 --MKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEE 158
             M  +EE +   +E       + E + + Q       EE
Sbjct: 829 EKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEE 868



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 35/143 (24%), Positives = 73/143 (51%), Gaps = 21/143 (14%)

Query: 6   KKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKR 65
           +K    +EK +    K ++    R    K R ++++ +  ++E  +  E+K +  E++  
Sbjct: 693 EKKTQEQEKKTWDQEKMREEESMREREKKMREEEEM-MREQEEKMQEQEEKMQEQEEEMW 751

Query: 66  KKEDK---------ERKKKDEEK------VKAEEESKKKEEEEKKKHQEEERKKQEEQAK 110
           ++E+K         E+++  E+K       K +E+ K  E+EEK + QEE+ + QEE+ +
Sbjct: 752 EQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMR 811

Query: 111 RQQEEEAAAQMKEKEESIQLHQE 133
            Q+E     +M+ +EE +   +E
Sbjct: 812 GQEE-----KMRGQEEKMWGQEE 829



 Score = 39.3 bits (90), Expect = 0.024
 Identities = 33/115 (28%), Positives = 58/115 (50%), Gaps = 20/115 (17%)

Query: 1   MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
           M  + +K    EEK              R    K R +++ K+  ++E     E+K    
Sbjct: 796 MRDQEEKMRGQEEK-------------MRGQEEKMRGQEE-KMWGQEEKMWGQEEKMWGQ 841

Query: 61  EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE 115
           E+    +E+K      EEK++ +EE K +E+EEK + QEE+ ++QEE+ + Q+E+
Sbjct: 842 EEKMWGQEEKM-----EEKMQGQEE-KMREQEEKMRGQEEKMREQEEKMRGQEEK 890



 Score = 35.4 bits (80), Expect = 0.35
 Identities = 48/241 (19%), Positives = 92/241 (38%), Gaps = 16/241 (6%)

Query: 1017 KDSKDSMTE-GENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEEN 1075
            +D ++ M E  E L E EE      +  EQ     E  + +E+E    D +E  +EEE  
Sbjct: 393  RDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERI 452

Query: 1076 TDYLTDSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKV 1135
             +      +E ET  E  E M K    +     E E+  +   +  L   +++  E  K+
Sbjct: 453  REREKKMREEEETMREQEEKMQK----QEENMWEQEE--KEWQQQRLPEQKEKLWEQEKM 506

Query: 1136 HQLDVAIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLA 1195
             + +  I    + ++R    + G E +    + M       +  + Q       M  Q  
Sbjct: 507  QEQEEKI-WEQEEKIRDQEEMWGQEKKMWRQEKM-------REQEDQMWEQEEKMRDQ-E 557

Query: 1196 ANHWNQQQAEQEERMRMKKLTLDINERQEQEDYQEMLQSLAQRPAPANTNRERRPRYQHP 1255
               W+Q++  +++    +K T D  E+  +E+     +   +        +E + + Q  
Sbjct: 558  QKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEE 617

Query: 1256 K 1256
            K
Sbjct: 618  K 618



 Score = 34.7 bits (78), Expect = 0.60
 Identities = 27/114 (23%), Positives = 48/114 (42%), Gaps = 10/114 (8%)

Query: 981  ELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGA 1040
            E LR K +     E+   QV+ +  E          K  ++   +  + EE  +EEE   
Sbjct: 404  ERLREKEERMREQEKMWEQVEKMREE----------KKMQEQEKKTRDQEEKMQEEERIR 453

Query: 1041 ETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTE 1094
            E E++   E E    +EE+    +++  E+EE+E         KE   ++E  +
Sbjct: 454  EREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQ 507



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 25/103 (24%), Positives = 53/103 (51%), Gaps = 8/103 (7%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDK----KKR 59
           + +K    EEK      K +   E+     ++    + K+  ++E     E+K    +++
Sbjct: 792 QEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEK 851

Query: 60  LEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEER 102
           +E+  + +E+K R++  EEK++ +EE  K  E+E+K   +EE+
Sbjct: 852 MEEKMQGQEEKMREQ--EEKMRGQEE--KMREQEEKMRGQEEK 890



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 33/159 (20%), Positives = 69/159 (43%), Gaps = 4/159 (2%)

Query: 981  ELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDK--DSKDSMTEGENLEEDEEEEEG 1038
            E +R + K     EE +R+ ++  +E   K+    +K  + ++ M E E  E+  E+EE 
Sbjct: 589  ERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQE--EKMWEQEEK 646

Query: 1039 GAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTEVMIK 1098
              E EE+   +  + E +E+        E E+ +E+          E +T E+  +   +
Sbjct: 647  MWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQ 706

Query: 1099 GGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQ 1137
                +     E E  ++  ++MM E  ++   +  K+ +
Sbjct: 707  EKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQE 745



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 4/79 (5%)

Query: 1020 KDSMTEGENLEEDE----EEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEEN 1075
            ++ M E E++ E E    EEEE   E EE+   + E  + +EEE  + ++   E+EE+  
Sbjct: 706  QEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMW 765

Query: 1076 TDYLTDSNKENETDEENTE 1094
                    KE   + E  +
Sbjct: 766  EQQRLPEQKEKLWEHEKMQ 784



 Score = 30.8 bits (68), Expect = 8.6
 Identities = 28/117 (23%), Positives = 52/117 (44%), Gaps = 12/117 (10%)

Query: 981  ELLRPKIKLCNSLEESIRQVQDL-EREFLIKLGLVNDKDSKDSMTEGENLEEDE-----E 1034
            + L P+++     EE  RQ ++L E+E  I+      K  +    + E L E E     +
Sbjct: 259  KFLLPQVQTNTLQEEMWRQEEELREQEKKIR------KQEEKMWRQEERLREQEGKMREQ 312

Query: 1035 EEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEE 1091
            EE+   + +     E E+ E E+E     +  E EE+ +E  + + +  ++    EE
Sbjct: 313  EEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEE 369



 Score = 30.8 bits (68), Expect = 8.6
 Identities = 21/80 (26%), Positives = 36/80 (45%), Gaps = 4/80 (5%)

Query: 1021 DSMTEGENLEEDEE----EEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENT 1076
            + M E E ++E EE    +E+   +T+EQ     +  +  EEE     + +  EEEE   
Sbjct: 671  EKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMR 730

Query: 1077 DYLTDSNKENETDEENTEVM 1096
            +      ++ E  +E  E M
Sbjct: 731  EQEEKMQEQEEKMQEQEEEM 750



 Score = 30.8 bits (68), Expect = 8.6
 Identities = 25/124 (20%), Positives = 57/124 (45%), Gaps = 8/124 (6%)

Query: 1018 DSKDSMTEGENLEEDE----EEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEE 1073
            + K+ + E E ++E E    +EE+   + E+  G E ++   EE+     +   G+EE+ 
Sbjct: 772  EQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKM 831

Query: 1074 -ENTDYLTDSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGES 1132
                + +    ++    EE  E  ++G   +     E E+ ++  ++ M E  ++  G+ 
Sbjct: 832  WGQEEKMWGQEEKMWGQEEKMEEKMQG---QEEKMREQEEKMRGQEEKMREQEEKMRGQE 888

Query: 1133 VKVH 1136
             K++
Sbjct: 889  EKIY 892


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 72.0 bits (175), Expect = 3e-12
 Identities = 46/148 (31%), Positives = 81/148 (54%), Gaps = 8/148 (5%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
           R+K   M E+  +   +EK   E++T   +++  D  +   ++E  +  E K +  E+  
Sbjct: 517 REKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMM 576

Query: 65  RKKEDK----ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 120
           R++E+K    E K +++E+   E+E K +E+EEK   QEE+  +QEE+ K Q++EE    
Sbjct: 577 REQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEE---M 633

Query: 121 MKEKEESIQLHQE-AWERHHLRKELRSK 147
           M E+EE +Q  +E  WE+    +E   K
Sbjct: 634 MWEQEEKMQEQEEKMWEQEEKMREQEEK 661



 Score = 67.4 bits (163), Expect = 8e-11
 Identities = 44/144 (30%), Positives = 83/144 (57%), Gaps = 12/144 (8%)

Query: 11  MEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDK 70
           M E+D     KE+   E++ +  +E    + K T ++E  K   D+++++ +++R +E +
Sbjct: 509 MWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQE--KKTWDQEEKMREEERMRE-R 565

Query: 71  ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEK------ 124
           E+K ++EE++  E+E K +E+EEK + QEE+  +QEE  K Q++EE   + +EK      
Sbjct: 566 EKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEE--KMQEQEEKMWEQEEKMWEQEE 623

Query: 125 EESIQLHQE-AWERHHLRKELRSK 147
           E+ +Q  +E  WE+    +E   K
Sbjct: 624 EDKMQEQEEMMWEQEEKMQEQEEK 647



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 44/180 (24%), Positives = 88/180 (48%), Gaps = 14/180 (7%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
           R++    E++  +   +EK   +   +  +E    + +   +++  +  E +K+  E +K
Sbjct: 238 RQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEK 297

Query: 65  RKKEDKERKKKDEEKVKAEE-----ESKKKEEEEKKKHQEE---ERKKQ---EEQAKRQQ 113
             +E K+ ++++E+  + EE     E K +E+EEK   QEE   E++KQ   +EQ  R Q
Sbjct: 298 ELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQ 357

Query: 114 EE---EAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKK 170
           EE   E   +++EKEE ++  ++ WE+    +E     +     R EE      +  ++K
Sbjct: 358 EERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQK 417



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 35/157 (22%), Positives = 90/157 (57%), Gaps = 3/157 (1%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
           R++  + E++    + +EK   E R    +++ +++ ++  ++E     +++K R +++K
Sbjct: 537 REEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEK 596

Query: 65  RKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE--EAAAQMK 122
             +++++ ++++E+  + EE+  ++EEE+K + QEE   +QEE+ + Q+E+  E   +M+
Sbjct: 597 MWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR 656

Query: 123 EKEESIQLHQEAWE-RHHLRKELRSKNQNAPDSRPEE 158
           E+EE ++  +E  + +    +E   K Q   +   E+
Sbjct: 657 EQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQ 693



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 41/165 (24%), Positives = 92/165 (55%), Gaps = 18/165 (10%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERP--KDDIKLTAKKEVSKAPEDK----KK 58
           R++   + E++     +EK+  E++ +  +E    + + K+  ++E  +  E+K    ++
Sbjct: 279 RRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE 338

Query: 59  RLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQ----EEERKKQEEQAKRQQE 114
           RL + +++  ++E+K +D+E+   E++ + +E+EE+ + Q    E+E K QEE+  R++E
Sbjct: 339 RLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRERE 398

Query: 115 E---EAAAQMKEKEESIQLHQE-AWERHHLRKELRSKNQNAPDSR 155
           +   E    M+E+EE +Q  +E  WE    ++E   + Q  P+ +
Sbjct: 399 KKMREEEETMREQEEKMQKQEENMWE----QEEKEWQQQRLPEQK 439



 Score = 61.2 bits (147), Expect = 6e-09
 Identities = 43/170 (25%), Positives = 81/170 (47%), Gaps = 16/170 (9%)

Query: 1   MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
           M  + +K    EEK      K  +  E+     +E    + +    ++  K  E ++K  
Sbjct: 590 MREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMW 649

Query: 61  EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEE---- 116
           E +++ +E +E+ ++ EEK++ +EE K +E+EEK + QEE+ ++QEE+ + Q+E+     
Sbjct: 650 EQEEKMREQEEKMREQEEKMQGQEE-KMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQE 708

Query: 117 -----------AAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSR 155
                         +M+EKEE I+  +E  +      E R      P S+
Sbjct: 709 EKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEPCLPPSK 758



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 45/169 (26%), Positives = 85/169 (50%), Gaps = 16/169 (9%)

Query: 1   MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
           M  E +     EEK      K ++  E+     ++  + + K+  ++E     E++ K  
Sbjct: 569 MREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQ 628

Query: 61  EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 120
           E ++   E +E+ ++ EEK+  +EE  + E+EEK + QEE+ + QEE+  R+QEE+   Q
Sbjct: 629 EQEEMMWEQEEKMQEQEEKMWEQEEKMR-EQEEKMREQEEKMQGQEEK-MREQEEKMQGQ 686

Query: 121 ---MKEKEESIQLHQE-AW----------ERHHLRKELRSKNQNAPDSR 155
              M+E+EE ++  +E  W          E+   ++E+R K +   D +
Sbjct: 687 EEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQK 735



 Score = 57.8 bits (138), Expect = 7e-08
 Identities = 38/146 (26%), Positives = 76/146 (52%), Gaps = 9/146 (6%)

Query: 1   MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
           M  + +K    EEK      K     ER     K+  + + K+  ++E     +++ +  
Sbjct: 312 MQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREK 371

Query: 61  EDDKRKKE---DKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEA 117
           E+  R++E   ++E K ++EE+++ E E K +EEEE  + QEE+ +KQEE    Q+E+E 
Sbjct: 372 EERMREQEKMWEQEEKMQEEERIR-EREKKMREEEETMREQEEKMQKQEENMWEQEEKEW 430

Query: 118 AAQMKEKEESIQLHQEAWERHHLRKE 143
             Q   +++     ++ WE+  ++++
Sbjct: 431 QQQRLPEQK-----EKLWEQEKMQEQ 451



 Score = 57.8 bits (138), Expect = 7e-08
 Identities = 43/217 (19%), Positives = 106/217 (48%), Gaps = 34/217 (15%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDK-------- 56
           R+K   M E++ +   +EK   E R    +++ +++ +   ++E     +++        
Sbjct: 369 REKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEK 428

Query: 57  ---KKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEE----EKKKHQEEERKKQEEQA 109
              ++RL + K K  ++E+ ++ EEK+  +EE  + +EE    EKK  ++E+ ++QE+Q 
Sbjct: 429 EWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQM 488

Query: 110 KRQQEE----------------EAAAQMKEKEESIQLHQEAWERHH-LRKELRSKNQNAP 152
             Q+E+                E   +++EKEE ++  ++ W++   +R+E +++ Q   
Sbjct: 489 WEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKK 548

Query: 153 DSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQRDSL 189
               EE    R +  +++    +++ + +  +Q + +
Sbjct: 549 TWDQEEKM--REEERMREREKKMREEEEMMREQEEKM 583



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 51/206 (24%), Positives = 104/206 (50%), Gaps = 31/206 (15%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
           +KK A ++EK  L  +++ +   +  V   +R  +  K    +  +   +++  R E++ 
Sbjct: 186 KKKNAELQEKLRLAESEKSEI--QLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEEL 243

Query: 65  RKKEDKERKKKD-----EEKVKAEEESKKKEEEEKKKHQEEERKKQE-----------EQ 108
           R++E K RK+++     EE+++ E+E K +E+EEK + QE+  ++QE           EQ
Sbjct: 244 REQEKKIRKQEEKMWRQEERLR-EQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQ 302

Query: 109 AKRQQEEEAAAQMKEK----EESIQLHQEAWERHHLR-----KELRSKNQNAPDSRPEEN 159
            K +++EE   + +EK    EE ++  +E   R   R     K++R + Q   D   EE 
Sbjct: 303 KKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQ--EER 360

Query: 160 FFSRLDSSLKKNTAFVKKLKTITEQQ 185
            + + D  L++    +++ + + EQ+
Sbjct: 361 MWEQ-DERLREKEERMREQEKMWEQE 385



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 39/134 (29%), Positives = 76/134 (56%), Gaps = 10/134 (7%)

Query: 12  EEKDSLPNNKEKDCSERRTVSSKERP--KDDIKLTAKKEVSKAPEDKKKRLEDDKRKKED 69
           E++D +   +EK   + + +  +E    + D +L  K+E  +  E KK   +++K ++E 
Sbjct: 483 EQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEE--RMREQKKMWQQEEKMREEK 540

Query: 70  K---ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE--EAAAQMKEK 124
           K   + KK  +++ K  EE + +E E+K + +EE  ++QEE+ + Q+E+  E   +M E+
Sbjct: 541 KTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQ 600

Query: 125 EESIQLHQE-AWER 137
           EE +Q  +E  WE+
Sbjct: 601 EEKMQEQEEKMWEQ 614



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 40/154 (25%), Positives = 83/154 (53%), Gaps = 18/154 (11%)

Query: 12  EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDK-----KKRLEDDKRK 66
           E+++ + + +E    E++    ++  + + ++  ++E  +  E K     ++  E D+R 
Sbjct: 457 EQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERL 516

Query: 67  KEDKERKKKDEEKVKAEE---ESKKKEEEEKK------KHQEEERKKQEEQAKRQQEE-- 115
           +E +ER ++ ++  + EE   E KK +E+EKK      K +EEER ++ E+  R++EE  
Sbjct: 517 REKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMM 576

Query: 116 -EAAAQMKEKEESIQLHQE-AWERHHLRKELRSK 147
            E   +M+E+EE ++  +E  WE+    +E   K
Sbjct: 577 REQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEK 610



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 39/142 (27%), Positives = 73/142 (51%), Gaps = 17/142 (11%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVS----KAPEDKKKR 59
           E KK    E+K      K ++    R    K R ++++    ++++     K  E ++K 
Sbjct: 538 EEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKM 597

Query: 60  LEDDKRKKEDKERKKKDEEKVKAEEESKKKEE--------EEKKKHQEEERKKQEEQAKR 111
            E +++ +E +E+  + EEK+  +EE  K +E        EEK + QEE+  +QEE+ + 
Sbjct: 598 WEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMRE 657

Query: 112 QQEEEAAAQMKEKEESIQLHQE 133
           Q+E     +M+E+EE +Q  +E
Sbjct: 658 QEE-----KMREQEEKMQGQEE 674



 Score = 54.7 bits (130), Expect = 6e-07
 Identities = 41/185 (22%), Positives = 96/185 (51%), Gaps = 10/185 (5%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
           R +   M E+D     KE+   E+  +  +E    + +   ++E     E++  R +++K
Sbjct: 355 RDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEK 414

Query: 65  RKKEDK---ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE-EAAAQ 120
            +K+++   E+++K+ ++ +  E+ +K  E+EK + QEE+  +QEE+ + Q+E      +
Sbjct: 415 MQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKK 474

Query: 121 MKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKT 180
           M  +E+  +   + WE+    +++R + Q   D   EE  + + D  L++    +++ K 
Sbjct: 475 MWRQEKMREQEDQMWEQ---EEKMRDQEQKMWDQ--EERMWEQ-DERLREKEERMREQKK 528

Query: 181 ITEQQ 185
           + +Q+
Sbjct: 529 MWQQE 533



 Score = 54.3 bits (129), Expect = 7e-07
 Identities = 35/191 (18%), Positives = 94/191 (49%), Gaps = 16/191 (8%)

Query: 12  EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDK----------KKRLE 61
           ++++++   +EK+  ++R    KE+  +  K+  ++E     E+K          +K++ 
Sbjct: 417 KQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMW 476

Query: 62  DDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQE---EQAKRQQEEEAA 118
             ++ +E +++  + EEK++ +E+    +EE   +  E  R+K+E   EQ K  Q+EE  
Sbjct: 477 RQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEE-- 534

Query: 119 AQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKL 178
            +M+E++++ +  ++ W++    +E     +     R EE      +  +++    +++ 
Sbjct: 535 -KMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQ 593

Query: 179 KTITEQQRDSL 189
           +    +Q + +
Sbjct: 594 EEKMWEQEEKM 604



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 41/167 (24%), Positives = 83/167 (49%), Gaps = 40/167 (23%)

Query: 21  KEKDCSE----RRTVSSKERPKDDIKL--------TAKKEVSKAPEDKKKRL-------- 60
           KE+D       R T++++E  K + +L        + K E+    ++ K++L        
Sbjct: 166 KERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLP 225

Query: 61  --------------EDDKRKKEDKERKKKD----EEKVKAEEESKKKEEEEKKKHQEEER 102
                         E++ R++E K RK+++    +E+   E+E K +E+EEK + QE+  
Sbjct: 226 QVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRL 285

Query: 103 KKQEEQAKRQQEE-EAAAQMKEKEESIQLHQE-AWERHHLRKELRSK 147
           ++QE++ + Q++E     +++E+EE +Q  +E  WE+    +E   K
Sbjct: 286 REQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEK 332



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 38/177 (21%), Positives = 88/177 (49%), Gaps = 11/177 (6%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSER-RTVSSKERP-KDDIKLTAKKEVSKAPEDKKKRLED 62
           R++   M E++     +EK   E+ + +  +E+  ++  KL  ++E  +  E+K    E+
Sbjct: 265 REQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEE 324

Query: 63  DKRKKEDK----ERKKKDEEKVKAEEESKKKEEEEKKKHQEE-----ERKKQEEQAKRQQ 113
             R++E+K    E +  ++EK   E+E K +++EE+   Q+E     E + +E++   +Q
Sbjct: 325 KMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQ 384

Query: 114 EEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKK 170
           EE+   + + +E   ++ +E        ++++ + +N  +   +E    RL    +K
Sbjct: 385 EEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK 441



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 36/167 (21%), Positives = 82/167 (49%), Gaps = 17/167 (10%)

Query: 1   MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
           +P +++K   + E++ +   +EK   +   +  +E      K   ++E  +  ED+   +
Sbjct: 435 LPEQKEK---LWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQ---M 488

Query: 61  EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEE---------ERKKQEEQAKR 111
            + + K  D+E+K  D+E+   E++ + +E+EE+ + Q++         E KK +EQ K+
Sbjct: 489 WEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKK 548

Query: 112 QQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEE 158
             ++E   +M+E+E   +  ++  E   + +E   K Q   +   E+
Sbjct: 549 TWDQE--EKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQ 593



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 30/135 (22%), Positives = 78/135 (57%), Gaps = 5/135 (3%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERP-KDDIKLTAKKEVSKAPEDKKKRLED 62
           E+++    +E+      K+    E++    +ER  + D +L  K+E  +  E    ++ +
Sbjct: 328 EQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE----KMWE 383

Query: 63  DKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMK 122
            + K +++ER ++ E+K++ EEE+ +++EE+ +K +E   +++E++ ++Q+  E   ++ 
Sbjct: 384 QEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLW 443

Query: 123 EKEESIQLHQEAWER 137
           E+E+  +  ++ WE+
Sbjct: 444 EQEKMQEQEEKIWEQ 458



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 32/142 (22%), Positives = 67/142 (47%), Gaps = 3/142 (2%)

Query: 994  EESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVN 1053
            E+ +R+ +++ RE   K+    +K  +      E  E+ +E+EE   E EE+   + E +
Sbjct: 566  EKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEED 625

Query: 1054 EPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTEVMIKGGGLKHVPCVEDEDF 1113
            + +E+E    + +E  +E+EE      +  +E E      E  ++G   +     E E+ 
Sbjct: 626  KMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQG---QEEKMREQEEK 682

Query: 1114 IQALDKMMLENLQQRSGESVKV 1135
            +Q  ++ M E  ++  G+  K+
Sbjct: 683  MQGQEEKMREQEEKMRGQEEKM 704



 Score = 38.1 bits (87), Expect = 0.054
 Identities = 47/229 (20%), Positives = 96/229 (41%), Gaps = 11/229 (4%)

Query: 1017 KDSKDSMTEGENLEEDEE---EEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEE 1073
            ++ ++ M E E + E EE   EEE   E E++   E E    +EE+    +++  E+EE+
Sbjct: 369  REKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEK 428

Query: 1074 ENTDYLTDSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESV 1133
            E         KE   ++E  +   +    +    + D++ +   +K M    + R  E  
Sbjct: 429  EWQQQRLPEQKEKLWEQEKMQEQ-EEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQ 487

Query: 1134 KVHQLDVAIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQ 1193
               Q +       K   ++       E   E  + M      +K  +Q+ K+     + +
Sbjct: 488  MWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERM---REQKKMWQQEEKMREEKKTQE 544

Query: 1194 LAANHWNQQQ-AEQEERMRMKKLTLDINE---RQEQEDYQEMLQSLAQR 1238
                 W+Q++   +EERMR ++  +   E   R+++E  QE  + + ++
Sbjct: 545  QEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQ 593



 Score = 35.4 bits (80), Expect = 0.35
 Identities = 48/250 (19%), Positives = 106/250 (42%), Gaps = 21/250 (8%)

Query: 993  LEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEV 1052
            L E   ++++ ++ +  +  +  +K +++   +  + EE   EEE   E E++   E E+
Sbjct: 516  LREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEM 575

Query: 1053 NEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTEVMIKGGGLKHVPCVEDED 1112
               E+EE     +++  E+EE+  +      ++ E   E  E M +          E+ED
Sbjct: 576  MR-EQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWE---------QEEED 625

Query: 1113 FIQALDKMMLENLQQRSGESVKVHQLDVAIPLHLKSQLRKGPPLGGGEGEAESADTMPFV 1172
             +Q  ++MM E  ++   +  K+ + +  +    +    +   + G E +    +     
Sbjct: 626  KMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEE---- 681

Query: 1173 MLTRKGNKQQFKILNVPMSSQLAANHWNQQQA--EQEERMRMKKLTLDINE--RQEQEDY 1228
                +G +++ +     M  Q     W Q++    QEE+M  ++   +  E  R ++E  
Sbjct: 682  --KMQGQEEKMREQEEKMRGQ-EEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKM 738

Query: 1229 QEMLQSLAQR 1238
            QE L    +R
Sbjct: 739  QERLPEHEER 748



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 52/241 (21%), Positives = 89/241 (36%), Gaps = 33/241 (13%)

Query: 43  LTAKKEVSKAPEDKKK--------------RLEDDKRKKEDKERKKKDEEKVKAEEESKK 88
           ++ K   +K  E KKK              R  D K+KK +     +        E    
Sbjct: 13  MSEKTRQNKLAEAKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPE----TTTSEGCHS 68

Query: 89  KEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKN 148
            E+E+K  HQ +E  ++E +A+         Q  E E ++   Q+A  R      L    
Sbjct: 69  PEDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDA-ARKFEDGNLGESK 127

Query: 149 QNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQ---QRDSLS-----HDFNGLNLSK 200
             A       +F   L  +L   + + KK     E+   +RD+LS     +      L K
Sbjct: 128 DLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKK 187

Query: 201 YIAEAVASIVEAKLKISDVNCAVHLCSLFHQRYADFAPSLL------QVWKKHFEARKEE 254
             AE    +  A+ + S++   V       +R     P +       ++W++  E R++E
Sbjct: 188 KNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQE 247

Query: 255 K 255
           K
Sbjct: 248 K 248



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 51/255 (20%), Positives = 104/255 (40%), Gaps = 30/255 (11%)

Query: 981  ELLRPKIKLCNSLEESIRQVQDL-EREFLIKLGLVNDKDSKDSMTEGENLEEDE-----E 1034
            + L P+++     EE  RQ ++L E+E  I+      K  +    + E L E E     +
Sbjct: 221  KFLLPQVQTNTLQEEMWRQEEELREQEKKIR------KQEEKMWRQEERLREQEGKMREQ 274

Query: 1035 EEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTE 1094
            EE+   + +     E E+ E E+E        E EE+ +E  + + +  ++    EE   
Sbjct: 275  EEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEK-- 332

Query: 1095 VMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDVAIPLHLKSQLRKGP 1154
                            E+ +   +K M E  Q+   +  ++ + D  +    + ++R+  
Sbjct: 333  ------------MWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERL-REKEERMREQE 379

Query: 1155 PLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWNQQQAE-QEERMRMK 1213
             +   E + +  + +       +  ++  +     M  Q   N W Q++ E Q++R+  +
Sbjct: 380  KMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQ-EENMWEQEEKEWQQQRLPEQ 438

Query: 1214 KLTLDINER-QEQED 1227
            K  L   E+ QEQE+
Sbjct: 439  KEKLWEQEKMQEQEE 453


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
           protein 6 [Homo sapiens]
          Length = 724

 Score = 70.9 bits (172), Expect = 8e-12
 Identities = 42/139 (30%), Positives = 79/139 (56%), Gaps = 6/139 (4%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
           + +K    EEK      K ++  E      ++  + + K+  ++E  +  E+K +R E+ 
Sbjct: 583 QEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEK 642

Query: 64  KRKKEDK----ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE--EA 117
            R++E K    E K +++E++  E+E K  E+EEK   QEE+ ++QEE+ +RQ+E+  E 
Sbjct: 643 IREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ 702

Query: 118 AAQMKEKEESIQLHQEAWE 136
             +++++EE +Q HQE  E
Sbjct: 703 EVRLRQQEEKMQEHQEHLE 721



 Score = 67.8 bits (164), Expect = 6e-11
 Identities = 44/152 (28%), Positives = 87/152 (57%), Gaps = 6/152 (3%)

Query: 1   MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
           M  + +K    EEK      K ++  E +    +E+ ++  ++T ++E  K  E ++K  
Sbjct: 566 MHDQEEKIREQEEKVWRQEEKIRE-QEEKIREQEEKIREQEEMTQEQE-EKMGEQEEKMC 623

Query: 61  EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE--EAA 118
           E +++ +E +E+ ++ EEK++ E+E K +E+EEK + QEE  ++QEE+   Q+E+  E  
Sbjct: 624 EQEEKMQEQEEKMRRQEEKIR-EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQE 682

Query: 119 AQMKEKEESIQLHQE-AWERHHLRKELRSKNQ 149
            +M+E+EE ++  +E  WE+    ++   K Q
Sbjct: 683 EKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 714



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 43/164 (26%), Positives = 87/164 (53%), Gaps = 6/164 (3%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
           R+K    E+++ +   +EK   +   +  +E    + +    ++  K  E ++K  E ++
Sbjct: 540 RQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEE 599

Query: 65  RKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE--EAAAQMK 122
           + +E +E  ++ EEK+  E+E K  E+EEK + QEE+ ++QEE+ + Q+++  E   +++
Sbjct: 600 KIREQEEMTQEQEEKM-GEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIR 658

Query: 123 EKEESIQLHQE-AWERHHLRKELRSKNQNAPDS--RPEENFFSR 163
           E+EE +Q  +E  WE+     E   K Q   +   R EE  + +
Sbjct: 659 EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ 702



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 49/198 (24%), Positives = 106/198 (53%), Gaps = 30/198 (15%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
           R++    E ++ +   +EK   +   +  +E      K+  ++E+    E+K +R E+  
Sbjct: 365 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEE-----KMRRQEEMMWEKEEKMRRQEEMM 419

Query: 65  RKKEDKERKKKD-----EEKV-----KAEEESKKKEEEEKKKHQE---EERKKQEEQAKR 111
            +KE+K R++++     EEK+     K  E+ K +E+EEK++ +E   E+ K+QE++AK 
Sbjct: 420 WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 479

Query: 112 QQEEEAAAQMKEKEESIQLHQE-AW---ERHHLRKELRSKNQNAPDSRPEENFFSRLDSS 167
            ++EE   +++E+EE I+  +E  W   E+ H ++++R +     + R E+    R +  
Sbjct: 480 WRQEE---KIREQEEKIREQEEKMWRQEEKIHEQEKIREE-----EKRQEQEEMWRQEEK 531

Query: 168 LKKNTAFVKKLKTITEQQ 185
           +++     ++ + I EQ+
Sbjct: 532 IREQEEIWRQKEKIHEQE 549



 Score = 61.6 bits (148), Expect = 5e-09
 Identities = 51/177 (28%), Positives = 94/177 (53%), Gaps = 19/177 (10%)

Query: 22  EKDCSERRTVSSKERPKDDIKLTAKK--EVSKAPEDKKKRLEDDKRKKEDKERKK----- 74
           EK+   RR        ++ I+   +K  E  K  E ++KR E++K ++++K +++     
Sbjct: 421 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 480

Query: 75  KDEEKVKAEEESKKKEEEEKKKHQEE---ERKKQEEQAKRQQEEEAAAQMKEKEESIQLH 131
           + EEK++ E+E K +E+EEK   QEE   E++K  E+ KRQ++EE    M  +EE I+  
Sbjct: 481 RQEEKIR-EQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEE----MWRQEEKIREQ 535

Query: 132 QEAW---ERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQ 185
           +E W   E+ H ++E + + Q     R EE    + +   ++     ++ + I EQ+
Sbjct: 536 EEIWRQKEKIHEQEE-KIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQE 591



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 45/193 (23%), Positives = 102/193 (52%), Gaps = 10/193 (5%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
           R++    E+++ +   +EK   +   +  +E+ +++ K   ++E+ +  E+K +  E+  
Sbjct: 481 RQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQ-EEKIREQEEIW 539

Query: 65  RKK----EDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE--EAA 118
           R+K    E +E+ +K EEK+  +EE K  ++EEK + QEE+  +QEE+ + Q+E+  E  
Sbjct: 540 RQKEKIHEQEEKIRKQEEKMWRQEE-KMHDQEEKIREQEEKVWRQEEKIREQEEKIREQE 598

Query: 119 AQMKEKEESIQLHQEAW-ERHHLRKELRSKNQNAPDS-RPEENFFSRLDSSLKKNTAFVK 176
            +++E+EE  Q  +E   E+     E   K Q   +  R +E      +  +++    ++
Sbjct: 599 EKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIR 658

Query: 177 KLKTITEQQRDSL 189
           + + + ++Q + +
Sbjct: 659 EQEEMMQEQEEKM 671



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 45/192 (23%), Positives = 99/192 (51%), Gaps = 10/192 (5%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
           R++   M EK+      E+   E+  +  +E  + + +   ++E  +  E K  R E+  
Sbjct: 427 RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 486

Query: 65  RKKEDKERKKKDEEKVKAEEESKKKEEE--EKKKHQEEERKKQEEQAKRQQEE--EAAAQ 120
           R++E+K R++  EEK+  +EE   ++E+  E++K QE+E   ++E+  R+QEE      +
Sbjct: 487 REQEEKIREQ--EEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK 544

Query: 121 MKEKEESIQLHQEAWERHHLR---KELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKK 177
           + E+EE I+  +E   R   +   +E + + Q     R EE    + +  +++    +++
Sbjct: 545 IHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQ-EEKIREQEEKIRE 603

Query: 178 LKTITEQQRDSL 189
            + +T++Q + +
Sbjct: 604 QEEMTQEQEEKM 615



 Score = 57.8 bits (138), Expect = 7e-08
 Identities = 40/131 (30%), Positives = 71/131 (54%), Gaps = 12/131 (9%)

Query: 34  KERPKDDIKLTAKKEVSKA-----PEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKK 88
           KE      KL A+ E ++       + ++K    +++ +E +E+ ++ EEK++ E+E K 
Sbjct: 333 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR-EQEEKI 391

Query: 89  KEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQE-AWERHHLRKELRSK 147
           +E+EEK + QEE   ++EE+ +RQ+E      M EKEE ++  +E  WE+    +EL  K
Sbjct: 392 REQEEKMRRQEEMMWEKEEKMRRQEE-----MMWEKEEKMRRQEEMMWEKEEKIRELEEK 446

Query: 148 NQNAPDSRPEE 158
                  R +E
Sbjct: 447 MHEQEKIREQE 457



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 50/214 (23%), Positives = 99/214 (46%), Gaps = 33/214 (15%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLED-- 62
           R+    M E++ +   +EK   E +    ++R + + K+  ++E  +  E+K +  E+  
Sbjct: 441 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKM 500

Query: 63  --------------DKRKKEDKERKKKDEEKVKAEEE-----SKKKEEEEKKKHQEEERK 103
                         ++ K++++E   + EEK++ +EE      K  E+EEK + QEE+  
Sbjct: 501 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMW 560

Query: 104 KQEEQAK------RQQEEEAAAQ---MKEKEESIQLHQE-AWERHHLRKELRSK--NQNA 151
           +QEE+        R+QEE+   Q   ++E+EE I+  +E   E+  + +E   K   Q  
Sbjct: 561 RQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEE 620

Query: 152 PDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQ 185
                EE    + +   ++     ++ K I EQ+
Sbjct: 621 KMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQE 654



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 42/172 (24%), Positives = 84/172 (48%), Gaps = 16/172 (9%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
           + +K    EEK      K  D  E+     ++  + + K+  ++E  +  E+K +  E+ 
Sbjct: 548 QEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEM 607

Query: 64  KRKKEDK----ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE---- 115
            +++E+K    E K  ++E+   E+E K + +EEK + QE++ ++QEE+ + Q+E     
Sbjct: 608 TQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ 667

Query: 116 -----EAAAQMKEKEESIQLHQEAWERHHLR---KELRSKNQNAPDSRPEEN 159
                E   +M E+EE +Q  +E   R   +   +E+R + Q       +E+
Sbjct: 668 EEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEH 719



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 37/149 (24%), Positives = 79/149 (53%), Gaps = 10/149 (6%)

Query: 47  KEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQE 106
           ++  K  E ++K  E +++ +E +E+ ++ EEK++ +EE    E+EEK + QEE   ++E
Sbjct: 365 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEE-MMWEKEEKMRRQEEMMWEKE 423

Query: 107 EQAKRQQE---------EEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPE 157
           E+ +RQ+E          E   +M E+E+  +  ++  E   +R++ + + Q A   R E
Sbjct: 424 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 483

Query: 158 ENFFSRLDSSLKKNTAFVKKLKTITEQQR 186
           E    + +   ++     ++ + I EQ++
Sbjct: 484 EKIREQEEKIREQEEKMWRQEEKIHEQEK 512



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 30/119 (25%), Positives = 64/119 (53%), Gaps = 2/119 (1%)

Query: 10  SMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKED 69
           + E+++ +   +EK C +   +  +E      +   +++  K  E ++K  E ++  +E 
Sbjct: 608 TQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ 667

Query: 70  KERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESI 128
           +E+  + EEK+  +EE  K +E+E+K  ++EE+  ++E   RQQEE+     +  E +I
Sbjct: 668 EEKMWEQEEKMCEQEE--KMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 724



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 39/177 (22%), Positives = 80/177 (45%), Gaps = 12/177 (6%)

Query: 21  KEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDK------KKRLEDDKRKKEDKERKK 74
           KEK+   +  +   E  K +I+L  K+   K    K      + + E D   KE +    
Sbjct: 281 KEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA 340

Query: 75  KDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEK----EESIQL 130
           K + +V+  E   +  +++++K   +E K QE + K Q++EE   + +EK    EE ++ 
Sbjct: 341 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRR 400

Query: 131 HQE-AWERHH-LRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQ 185
            +E  WE+   +R++     +     R +E      +  +++    + + + I EQ+
Sbjct: 401 QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQE 457



 Score = 35.0 bits (79), Expect = 0.46
 Identities = 27/116 (23%), Positives = 55/116 (47%), Gaps = 8/116 (6%)

Query: 981  ELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGA 1040
            E +R + +     EE IR+ +++ +E   K+G     + ++ M E E   +++EE+    
Sbjct: 585  EKIREQEEKIREQEEKIREQEEMTQEQEEKMG-----EQEEKMCEQEEKMQEQEEK---M 636

Query: 1041 ETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTEVM 1096
              +E+   E E    E+EE     ++  +E+EE+  +      ++ E  +E  E M
Sbjct: 637  RRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 692



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 59/286 (20%), Positives = 113/286 (39%), Gaps = 33/286 (11%)

Query: 994  EESIRQVQDLEREFLIKLG----LVNDKDSKDSMTEGENLEEDE----------EEEEGG 1039
            EE IR+ ++  RE   K+     ++ +K+ K    E    E++E          E+EE  
Sbjct: 381  EEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 440

Query: 1040 AETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDE---ENTEVM 1096
             E EE+   + ++ E EE+   +    E E+ +E+         K  E +E   E  E M
Sbjct: 441  RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKM 500

Query: 1097 IKGGGLKH-VPCVEDEDFIQALDKMMLENLQQRSGESV-----KVHQLDVAIPLHLKSQL 1150
             +     H    + +E+  Q  ++M  +  + R  E +     K+H+ +  I    +   
Sbjct: 501  WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMW 560

Query: 1151 RKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWNQQQAEQEERM 1210
            R+   +   E +    +   +     K  +Q+ KI       +       +   EQEE+M
Sbjct: 561  RQEEKMHDQEEKIREQEEKVW-RQEEKIREQEEKI----REQEEKIREQEEMTQEQEEKM 615

Query: 1211 RMKKLTLDINERQEQEDYQEMLQSLAQRPAPANTNRERRPRYQHPK 1256
              ++  +   E + QE  ++M     +R       +E++ R Q  K
Sbjct: 616  GEQEEKMCEQEEKMQEQEEKM-----RRQEEKIREQEKKIREQEEK 656



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 53/260 (20%), Positives = 104/260 (40%), Gaps = 40/260 (15%)

Query: 994  EESIRQVQDLEREFLIKLGLVNDK-DSKDSMTEGENLEEDEE---EEEGGAETEEQSGNE 1049
            EE IR+ ++  RE   K+    +K   ++ + E E  +E EE   +EE   E EE    +
Sbjct: 483  EEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQK 542

Query: 1050 SEVNEPEE-----------EEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTEVMIK 1098
             +++E EE           +E   +D +E   E+EE      +  +E E      E  I+
Sbjct: 543  EKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIR 602

Query: 1099 GGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDVAIPLHLKSQLRKGPPLGG 1158
                      E E+  Q  ++ M E  ++   +  K+ + +  +    +    +   +  
Sbjct: 603  ----------EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIRE 652

Query: 1159 GEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWNQQQAEQEERMRMKKLTL- 1217
             E +    + M      +   +++       M  Q       ++  EQEE+MR ++  + 
Sbjct: 653  QEEKIREQEEMMQEQEEKMWEQEE------KMCEQ------EEKMQEQEEKMRRQEEKMW 700

Query: 1218 --DINERQEQEDYQEMLQSL 1235
              ++  RQ++E  QE  + L
Sbjct: 701  EQEVRLRQQEEKMQEHQEHL 720



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 38/182 (20%), Positives = 83/182 (45%), Gaps = 19/182 (10%)

Query: 21  KEKDCSE----RRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKD 76
           KE+D       R T++ +E  + + KL  K ++ ++ + + +    + ++K ++ +    
Sbjct: 261 KERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLP 320

Query: 77  EEKVKAEEESKKKEEEE---KKKHQEEE-----RKKQEEQAKRQQEEEAAAQMKEK---- 124
           +++++AE +   KE +    K + Q EE     R  Q+++ K  ++EE   + +EK    
Sbjct: 321 QQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ 380

Query: 125 EESIQLHQE---AWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTI 181
           EE I+  +E     E    R+E     +     R EE  + + +   ++     +K + I
Sbjct: 381 EEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 440

Query: 182 TE 183
            E
Sbjct: 441 RE 442



 Score = 31.2 bits (69), Expect = 6.6
 Identities = 27/109 (24%), Positives = 53/109 (48%), Gaps = 7/109 (6%)

Query: 64  KRKKEDK--ERKKKDEEKVKAE-EESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 120
           ++KK D+  E   K+ + +  E   +   +EE K+K+ + + K Q  ++++ + +    +
Sbjct: 248 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE 307

Query: 121 MKEKEESIQL----HQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLD 165
           +K K E  +L     Q   E  HL KEL+S +        E   ++RL+
Sbjct: 308 LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN 356


>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
           sapiens]
          Length = 1293

 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 43/117 (36%), Positives = 75/117 (64%), Gaps = 6/117 (5%)

Query: 48  EVSKAPEDKKKRLEDDKR-KKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEE--RKK 104
           E +KA + +++R E + R K+E++ERK+++E + + EE  ++++EEE+K+ +EEE  R+K
Sbjct: 724 EKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRK 783

Query: 105 QEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRK---ELRSKNQNAPDSRPEE 158
           QEE  +RQ+E+E A + + +EE  Q  +EA  R   R+   E R K +     + EE
Sbjct: 784 QEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEE 840



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 55/197 (27%), Positives = 112/197 (56%), Gaps = 31/197 (15%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
           E+ K A +E++      +E +   +R    ++R +++++   ++ + +  E+++KR E++
Sbjct: 724 EKAKAAKLEQE-----RREAEMRAKREEEERKR-QEELRRQQEEILRRQQEEERKRREEE 777

Query: 64  ---KRKKEDKERKKKDEE---KVKAEEESKKKEEE-----EKKKHQEEERKKQEEQAKRQ 112
              +RK+E+  R+++++E   + + EEE ++++EE     E+++ +EEER+KQEE   R+
Sbjct: 778 ELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE-LLRK 836

Query: 113 QEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNT 172
           QEEEAA   +E+EE+    Q   E + LR E     + A   R EE    R +  +++  
Sbjct: 837 QEEEAAKWAREEEEA----QRRLEENRLRME-----EEAARLRHEEEERKRKELEVQRQ- 886

Query: 173 AFVKKLKTITEQQRDSL 189
              K+L    +QQ+++L
Sbjct: 887 ---KELMRQRQQQQEAL 900



 Score = 64.7 bits (156), Expect = 5e-10
 Identities = 37/130 (28%), Positives = 76/130 (58%), Gaps = 6/130 (4%)

Query: 45  AKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERK- 103
           A +++ +  + K  +LE ++R+ E   R K++EE+ K +EE ++++EE  ++ QEEERK 
Sbjct: 716 ALEQLQQLEKAKAAKLEQERREAE--MRAKREEEERKRQEELRRQQEEILRRQQEEERKR 773

Query: 104 KQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELR---SKNQNAPDSRPEENF 160
           ++EE+  R+++EEA  + +E+E +++  +E  ER    + LR    + +   + R +E  
Sbjct: 774 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL 833

Query: 161 FSRLDSSLKK 170
             + +    K
Sbjct: 834 LRKQEEEAAK 843



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 39/141 (27%), Positives = 86/141 (60%), Gaps = 13/141 (9%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
           E ++ A  +++++L   +E++ + RR    +ER + +  L   +E  +  E+++K+ E+ 
Sbjct: 775 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQ-EEL 833

Query: 64  KRKKEDKERK--KKDEEKVKAEEESKKKEEEE--KKKHQEEERKKQEEQA--------KR 111
            RK+E++  K  +++EE  +  EE++ + EEE  + +H+EEERK++E +         +R
Sbjct: 834 LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQR 893

Query: 112 QQEEEAAAQMKEKEESIQLHQ 132
           QQ++EA  +++++++  QL Q
Sbjct: 894 QQQQEALRRLQQQQQQQQLAQ 914



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 31/118 (26%), Positives = 64/118 (54%), Gaps = 12/118 (10%)

Query: 12  EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSK---APEDKKKRLEDDK-RKK 67
           EE+        +   ERR    + R ++++    ++E +K     E+ ++RLE+++ R +
Sbjct: 804 EEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME 863

Query: 68  EDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKR---QQEEEAAAQMK 122
           E+  R + +E     EE  +K+ E +++K    +R++Q+E  +R   QQ+++  AQMK
Sbjct: 864 EEAARLRHEE-----EERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMK 916



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 41/216 (18%), Positives = 94/216 (43%), Gaps = 57/216 (26%)

Query: 4    ERKKPASM---EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
            ER+K   +   +E+++    +E++ ++RR   ++ R +++      +E     E K+K L
Sbjct: 826  ERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEE----EERKRKEL 881

Query: 61   EDDKRKKEDKERKKKDEEKVKAEE------------------------------------ 84
            E  ++K+  ++R+++ E   + ++                                    
Sbjct: 882  EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLA 941

Query: 85   ESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMK------------EKEESIQLHQ 132
            E +K EEE +++ +EE+R++Q E  K  Q+++   Q K              +  +++ Q
Sbjct: 942  EIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ 1001

Query: 133  EAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSL 168
            E  E   ++K+ + + Q+   +R   N  S L +S+
Sbjct: 1002 E--EARQMQKQQQQQQQHQQPNRARNNTHSNLHTSI 1035



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 19/70 (27%), Positives = 32/70 (45%)

Query: 1021 DSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLT 1080
            D+ T G  LE+ ++ E+  A   EQ   E+E+    EEE     ++   ++EE       
Sbjct: 709  DTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE 768

Query: 1081 DSNKENETDE 1090
            +  K  E +E
Sbjct: 769  EERKRREEEE 778



 Score = 30.8 bits (68), Expect = 8.6
 Identities = 25/97 (25%), Positives = 40/97 (41%), Gaps = 13/97 (13%)

Query: 1009 IKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAET-----------EEQSGNESEVNEPEE 1057
            ++ G  +  D +DS+ E     ED EEE G  ++           +E    E E++    
Sbjct: 265  VRSGSGSIDDDRDSLPEW--CLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPV 322

Query: 1058 EEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTE 1094
            +EG +  D EG   EE      T+  +  +TD    E
Sbjct: 323  DEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVE 359


>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
           sapiens]
          Length = 1320

 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 43/117 (36%), Positives = 75/117 (64%), Gaps = 6/117 (5%)

Query: 48  EVSKAPEDKKKRLEDDKR-KKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEE--RKK 104
           E +KA + +++R E + R K+E++ERK+++E + + EE  ++++EEE+K+ +EEE  R+K
Sbjct: 751 EKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRK 810

Query: 105 QEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRK---ELRSKNQNAPDSRPEE 158
           QEE  +RQ+E+E A + + +EE  Q  +EA  R   R+   E R K +     + EE
Sbjct: 811 QEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEE 867



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 55/197 (27%), Positives = 112/197 (56%), Gaps = 31/197 (15%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
           E+ K A +E++      +E +   +R    ++R +++++   ++ + +  E+++KR E++
Sbjct: 751 EKAKAAKLEQE-----RREAEMRAKREEEERKR-QEELRRQQEEILRRQQEEERKRREEE 804

Query: 64  ---KRKKEDKERKKKDEE---KVKAEEESKKKEEE-----EKKKHQEEERKKQEEQAKRQ 112
              +RK+E+  R+++++E   + + EEE ++++EE     E+++ +EEER+KQEE   R+
Sbjct: 805 ELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE-LLRK 863

Query: 113 QEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNT 172
           QEEEAA   +E+EE+    Q   E + LR E     + A   R EE    R +  +++  
Sbjct: 864 QEEEAAKWAREEEEA----QRRLEENRLRME-----EEAARLRHEEEERKRKELEVQRQ- 913

Query: 173 AFVKKLKTITEQQRDSL 189
              K+L    +QQ+++L
Sbjct: 914 ---KELMRQRQQQQEAL 927



 Score = 64.7 bits (156), Expect = 5e-10
 Identities = 37/130 (28%), Positives = 76/130 (58%), Gaps = 6/130 (4%)

Query: 45  AKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERK- 103
           A +++ +  + K  +LE ++R+ E   R K++EE+ K +EE ++++EE  ++ QEEERK 
Sbjct: 743 ALEQLQQLEKAKAAKLEQERREAE--MRAKREEEERKRQEELRRQQEEILRRQQEEERKR 800

Query: 104 KQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELR---SKNQNAPDSRPEENF 160
           ++EE+  R+++EEA  + +E+E +++  +E  ER    + LR    + +   + R +E  
Sbjct: 801 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL 860

Query: 161 FSRLDSSLKK 170
             + +    K
Sbjct: 861 LRKQEEEAAK 870



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 39/141 (27%), Positives = 86/141 (60%), Gaps = 13/141 (9%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
           E ++ A  +++++L   +E++ + RR    +ER + +  L   +E  +  E+++K+ E+ 
Sbjct: 802 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQ-EEL 860

Query: 64  KRKKEDKERK--KKDEEKVKAEEESKKKEEEE--KKKHQEEERKKQEEQA--------KR 111
            RK+E++  K  +++EE  +  EE++ + EEE  + +H+EEERK++E +         +R
Sbjct: 861 LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQR 920

Query: 112 QQEEEAAAQMKEKEESIQLHQ 132
           QQ++EA  +++++++  QL Q
Sbjct: 921 QQQQEALRRLQQQQQQQQLAQ 941



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 31/118 (26%), Positives = 64/118 (54%), Gaps = 12/118 (10%)

Query: 12  EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSK---APEDKKKRLEDDK-RKK 67
           EE+        +   ERR    + R ++++    ++E +K     E+ ++RLE+++ R +
Sbjct: 831 EEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME 890

Query: 68  EDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKR---QQEEEAAAQMK 122
           E+  R + +E     EE  +K+ E +++K    +R++Q+E  +R   QQ+++  AQMK
Sbjct: 891 EEAARLRHEE-----EERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMK 943



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 41/216 (18%), Positives = 94/216 (43%), Gaps = 57/216 (26%)

Query: 4    ERKKPASM---EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
            ER+K   +   +E+++    +E++ ++RR   ++ R +++      +E     E K+K L
Sbjct: 853  ERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEE----EERKRKEL 908

Query: 61   EDDKRKKEDKERKKKDEEKVKAEE------------------------------------ 84
            E  ++K+  ++R+++ E   + ++                                    
Sbjct: 909  EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLA 968

Query: 85   ESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMK------------EKEESIQLHQ 132
            E +K EEE +++ +EE+R++Q E  K  Q+++   Q K              +  +++ Q
Sbjct: 969  EIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ 1028

Query: 133  EAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSL 168
            E  E   ++K+ + + Q+   +R   N  S L +S+
Sbjct: 1029 E--EARQMQKQQQQQQQHQQPNRARNNTHSNLHTSI 1062



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 19/70 (27%), Positives = 32/70 (45%)

Query: 1021 DSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLT 1080
            D+ T G  LE+ ++ E+  A   EQ   E+E+    EEE     ++   ++EE       
Sbjct: 736  DTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE 795

Query: 1081 DSNKENETDE 1090
            +  K  E +E
Sbjct: 796  EERKRREEEE 805


>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
           sapiens]
          Length = 1299

 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 43/117 (36%), Positives = 75/117 (64%), Gaps = 6/117 (5%)

Query: 48  EVSKAPEDKKKRLEDDKR-KKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEE--RKK 104
           E +KA + +++R E + R K+E++ERK+++E + + EE  ++++EEE+K+ +EEE  R+K
Sbjct: 730 EKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRK 789

Query: 105 QEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRK---ELRSKNQNAPDSRPEE 158
           QEE  +RQ+E+E A + + +EE  Q  +EA  R   R+   E R K +     + EE
Sbjct: 790 QEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEE 846



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 55/197 (27%), Positives = 112/197 (56%), Gaps = 31/197 (15%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
           E+ K A +E++      +E +   +R    ++R +++++   ++ + +  E+++KR E++
Sbjct: 730 EKAKAAKLEQE-----RREAEMRAKREEEERKR-QEELRRQQEEILRRQQEEERKRREEE 783

Query: 64  ---KRKKEDKERKKKDEE---KVKAEEESKKKEEE-----EKKKHQEEERKKQEEQAKRQ 112
              +RK+E+  R+++++E   + + EEE ++++EE     E+++ +EEER+KQEE   R+
Sbjct: 784 ELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE-LLRK 842

Query: 113 QEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNT 172
           QEEEAA   +E+EE+    Q   E + LR E     + A   R EE    R +  +++  
Sbjct: 843 QEEEAAKWAREEEEA----QRRLEENRLRME-----EEAARLRHEEEERKRKELEVQRQ- 892

Query: 173 AFVKKLKTITEQQRDSL 189
              K+L    +QQ+++L
Sbjct: 893 ---KELMRQRQQQQEAL 906



 Score = 64.7 bits (156), Expect = 5e-10
 Identities = 37/130 (28%), Positives = 76/130 (58%), Gaps = 6/130 (4%)

Query: 45  AKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERK- 103
           A +++ +  + K  +LE ++R+ E   R K++EE+ K +EE ++++EE  ++ QEEERK 
Sbjct: 722 ALEQLQQLEKAKAAKLEQERREAE--MRAKREEEERKRQEELRRQQEEILRRQQEEERKR 779

Query: 104 KQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELR---SKNQNAPDSRPEENF 160
           ++EE+  R+++EEA  + +E+E +++  +E  ER    + LR    + +   + R +E  
Sbjct: 780 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL 839

Query: 161 FSRLDSSLKK 170
             + +    K
Sbjct: 840 LRKQEEEAAK 849



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 39/141 (27%), Positives = 86/141 (60%), Gaps = 13/141 (9%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
           E ++ A  +++++L   +E++ + RR    +ER + +  L   +E  +  E+++K+ E+ 
Sbjct: 781 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQ-EEL 839

Query: 64  KRKKEDKERK--KKDEEKVKAEEESKKKEEEE--KKKHQEEERKKQEEQA--------KR 111
            RK+E++  K  +++EE  +  EE++ + EEE  + +H+EEERK++E +         +R
Sbjct: 840 LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQR 899

Query: 112 QQEEEAAAQMKEKEESIQLHQ 132
           QQ++EA  +++++++  QL Q
Sbjct: 900 QQQQEALRRLQQQQQQQQLAQ 920



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 31/118 (26%), Positives = 64/118 (54%), Gaps = 12/118 (10%)

Query: 12  EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSK---APEDKKKRLEDDK-RKK 67
           EE+        +   ERR    + R ++++    ++E +K     E+ ++RLE+++ R +
Sbjct: 810 EEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME 869

Query: 68  EDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKR---QQEEEAAAQMK 122
           E+  R + +E     EE  +K+ E +++K    +R++Q+E  +R   QQ+++  AQMK
Sbjct: 870 EEAARLRHEE-----EERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMK 922



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 41/216 (18%), Positives = 94/216 (43%), Gaps = 57/216 (26%)

Query: 4    ERKKPASM---EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
            ER+K   +   +E+++    +E++ ++RR   ++ R +++      +E     E K+K L
Sbjct: 832  ERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEE----EERKRKEL 887

Query: 61   EDDKRKKEDKERKKKDEEKVKAEE------------------------------------ 84
            E  ++K+  ++R+++ E   + ++                                    
Sbjct: 888  EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLA 947

Query: 85   ESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMK------------EKEESIQLHQ 132
            E +K EEE +++ +EE+R++Q E  K  Q+++   Q K              +  +++ Q
Sbjct: 948  EIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ 1007

Query: 133  EAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSL 168
            E  E   ++K+ + + Q+   +R   N  S L +S+
Sbjct: 1008 E--EARQMQKQQQQQQQHQQPNRARNNTHSNLHTSI 1041



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 19/70 (27%), Positives = 32/70 (45%)

Query: 1021 DSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLT 1080
            D+ T G  LE+ ++ E+  A   EQ   E+E+    EEE     ++   ++EE       
Sbjct: 715  DTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE 774

Query: 1081 DSNKENETDE 1090
            +  K  E +E
Sbjct: 775  EERKRREEEE 784



 Score = 30.8 bits (68), Expect = 8.6
 Identities = 25/97 (25%), Positives = 40/97 (41%), Gaps = 13/97 (13%)

Query: 1009 IKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAET-----------EEQSGNESEVNEPEE 1057
            ++ G  +  D +DS+ E     ED EEE G  ++           +E    E E++    
Sbjct: 271  VRSGSGSIDDDRDSLPEW--CLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPV 328

Query: 1058 EEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTE 1094
            +EG +  D EG   EE      T+  +  +TD    E
Sbjct: 329  DEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVE 365


>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
           sapiens]
          Length = 1299

 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 43/117 (36%), Positives = 75/117 (64%), Gaps = 6/117 (5%)

Query: 48  EVSKAPEDKKKRLEDDKR-KKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEE--RKK 104
           E +KA + +++R E + R K+E++ERK+++E + + EE  ++++EEE+K+ +EEE  R+K
Sbjct: 730 EKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRK 789

Query: 105 QEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRK---ELRSKNQNAPDSRPEE 158
           QEE  +RQ+E+E A + + +EE  Q  +EA  R   R+   E R K +     + EE
Sbjct: 790 QEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEE 846



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 55/197 (27%), Positives = 112/197 (56%), Gaps = 31/197 (15%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
           E+ K A +E++      +E +   +R    ++R +++++   ++ + +  E+++KR E++
Sbjct: 730 EKAKAAKLEQE-----RREAEMRAKREEEERKR-QEELRRQQEEILRRQQEEERKRREEE 783

Query: 64  ---KRKKEDKERKKKDEE---KVKAEEESKKKEEE-----EKKKHQEEERKKQEEQAKRQ 112
              +RK+E+  R+++++E   + + EEE ++++EE     E+++ +EEER+KQEE   R+
Sbjct: 784 ELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE-LLRK 842

Query: 113 QEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNT 172
           QEEEAA   +E+EE+    Q   E + LR E     + A   R EE    R +  +++  
Sbjct: 843 QEEEAAKWAREEEEA----QRRLEENRLRME-----EEAARLRHEEEERKRKELEVQRQ- 892

Query: 173 AFVKKLKTITEQQRDSL 189
              K+L    +QQ+++L
Sbjct: 893 ---KELMRQRQQQQEAL 906



 Score = 64.7 bits (156), Expect = 5e-10
 Identities = 37/130 (28%), Positives = 76/130 (58%), Gaps = 6/130 (4%)

Query: 45  AKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERK- 103
           A +++ +  + K  +LE ++R+ E   R K++EE+ K +EE ++++EE  ++ QEEERK 
Sbjct: 722 ALEQLQQLEKAKAAKLEQERREAE--MRAKREEEERKRQEELRRQQEEILRRQQEEERKR 779

Query: 104 KQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELR---SKNQNAPDSRPEENF 160
           ++EE+  R+++EEA  + +E+E +++  +E  ER    + LR    + +   + R +E  
Sbjct: 780 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL 839

Query: 161 FSRLDSSLKK 170
             + +    K
Sbjct: 840 LRKQEEEAAK 849



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 39/141 (27%), Positives = 86/141 (60%), Gaps = 13/141 (9%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
           E ++ A  +++++L   +E++ + RR    +ER + +  L   +E  +  E+++K+ E+ 
Sbjct: 781 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQ-EEL 839

Query: 64  KRKKEDKERK--KKDEEKVKAEEESKKKEEEE--KKKHQEEERKKQEEQA--------KR 111
            RK+E++  K  +++EE  +  EE++ + EEE  + +H+EEERK++E +         +R
Sbjct: 840 LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQR 899

Query: 112 QQEEEAAAQMKEKEESIQLHQ 132
           QQ++EA  +++++++  QL Q
Sbjct: 900 QQQQEALRRLQQQQQQQQLAQ 920



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 31/118 (26%), Positives = 64/118 (54%), Gaps = 12/118 (10%)

Query: 12  EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSK---APEDKKKRLEDDK-RKK 67
           EE+        +   ERR    + R ++++    ++E +K     E+ ++RLE+++ R +
Sbjct: 810 EEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME 869

Query: 68  EDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKR---QQEEEAAAQMK 122
           E+  R + +E     EE  +K+ E +++K    +R++Q+E  +R   QQ+++  AQMK
Sbjct: 870 EEAARLRHEE-----EERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMK 922



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 41/216 (18%), Positives = 94/216 (43%), Gaps = 57/216 (26%)

Query: 4    ERKKPASM---EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
            ER+K   +   +E+++    +E++ ++RR   ++ R +++      +E     E K+K L
Sbjct: 832  ERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEE----EERKRKEL 887

Query: 61   EDDKRKKEDKERKKKDEEKVKAEE------------------------------------ 84
            E  ++K+  ++R+++ E   + ++                                    
Sbjct: 888  EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLA 947

Query: 85   ESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMK------------EKEESIQLHQ 132
            E +K EEE +++ +EE+R++Q E  K  Q+++   Q K              +  +++ Q
Sbjct: 948  EIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ 1007

Query: 133  EAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSL 168
            E  E   ++K+ + + Q+   +R   N  S L +S+
Sbjct: 1008 E--EARQMQKQQQQQQQHQQPNRARNNTHSNLHTSI 1041



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 19/70 (27%), Positives = 32/70 (45%)

Query: 1021 DSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLT 1080
            D+ T G  LE+ ++ E+  A   EQ   E+E+    EEE     ++   ++EE       
Sbjct: 715  DTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE 774

Query: 1081 DSNKENETDE 1090
            +  K  E +E
Sbjct: 775  EERKRREEEE 784



 Score = 30.8 bits (68), Expect = 8.6
 Identities = 25/97 (25%), Positives = 40/97 (41%), Gaps = 13/97 (13%)

Query: 1009 IKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAET-----------EEQSGNESEVNEPEE 1057
            ++ G  +  D +DS+ E     ED EEE G  ++           +E    E E++    
Sbjct: 271  VRSGSGSIDDDRDSLPEW--CLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPV 328

Query: 1058 EEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTE 1094
            +EG +  D EG   EE      T+  +  +TD    E
Sbjct: 329  DEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVE 365


>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
          Length = 793

 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 41/198 (20%), Positives = 97/198 (48%), Gaps = 14/198 (7%)

Query: 3   AERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLED 62
           A+ +     EEK +    + ++  ER  +  +E+   + +   K+E  +A E++++  E+
Sbjct: 289 ADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEE 348

Query: 63  DKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE------- 115
           +KR  E+++R K++E++   E +  + EEEEK K +E++R KQ E+ K   +E       
Sbjct: 349 EKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEK 408

Query: 116 -------EAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSL 168
                  +   + K +E+ +Q      +      ++++K +   + +P        D  +
Sbjct: 409 VEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKI 468

Query: 169 KKNTAFVKKLKTITEQQR 186
           KK+    +++K+  ++++
Sbjct: 469 KKDKEPKEEVKSFMDRKK 486



 Score = 67.8 bits (164), Expect = 6e-11
 Identities = 53/199 (26%), Positives = 99/199 (49%), Gaps = 20/199 (10%)

Query: 3   AERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLED 62
           AER +  + E +       +K   ER  + ++E      K  A++   +  E++++  E+
Sbjct: 267 AERARLEAEERERIKAEQDKKIADERARIEAEE------KAAAQERERREAEERERMREE 320

Query: 63  DKRKKEDKERKKKDEEKVKAEEESKKKEE-----EEKKKHQEEERKKQEEQAKRQQEEEA 117
           +KR  E+++R  K+EEK  AEE  + KEE     EE+++ +EEE++  EE+ + + EEE 
Sbjct: 321 EKRAAEERQR-IKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEE 379

Query: 118 AAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKK 177
            A+++E++ + QL     E+ H  +E + K +        +    +     K  TA +KK
Sbjct: 380 KAKVEEQKRNKQLE----EKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKK 435

Query: 178 ----LKTITEQQRDSLSHD 192
                 T  + +R+ L  D
Sbjct: 436 QGEEKGTKVQAKREKLQED 454



 Score = 63.9 bits (154), Expect = 9e-10
 Identities = 41/168 (24%), Positives = 94/168 (55%), Gaps = 6/168 (3%)

Query: 18  PNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDE 77
           P  +E+       +S  E+ +++ K  A+ E ++   ++++R++ ++ KK   ER + + 
Sbjct: 238 PKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEA 297

Query: 78  EKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKE--KEESIQLHQEAW 135
           E+  A +E +++E EE+++ +EEE++  EE+ + ++EE+ AA+ ++  KEE     + A 
Sbjct: 298 EEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEE---KRAAE 354

Query: 136 ERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITE 183
           ER  +++E +   +    +R EE   ++++   K+N    +K   + E
Sbjct: 355 ERQRIKEEEKRAAEERQRARAEEEEKAKVEEQ-KRNKQLEEKKHAMQE 401



 Score = 63.9 bits (154), Expect = 9e-10
 Identities = 45/174 (25%), Positives = 94/174 (54%), Gaps = 16/174 (9%)

Query: 1   MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
           M  E K+ A  EE+  +   +++   ER+ +  +E+   + +   K+E  +A E++++  
Sbjct: 317 MREEEKRAA--EERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRAR 374

Query: 61  --EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEE---ERKKQEEQAK----R 111
             E++K K E+++R K+ EEK  A +E+K K E+ ++K + +   E+K QE++ +    +
Sbjct: 375 AEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLK 434

Query: 112 QQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLD 165
           +Q EE   +++ K E +Q  +  +++  ++ E   K     D  P+E   S +D
Sbjct: 435 KQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKK-----DKEPKEEVKSFMD 483



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 39/152 (25%), Positives = 83/152 (54%), Gaps = 12/152 (7%)

Query: 11  MEEKDSLPNNKEKDCSERRTVSSKERPK---DDIKLTAKKEVSKAPEDKKKRLEDDKRKK 67
           MEE+D     KE+  +ER  + ++ER +   +  K  A +      E+K    E ++R+ 
Sbjct: 257 MEEED-----KERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREA 311

Query: 68  EDKERKKKDEEKVKAEEESKKKEE----EEKKKHQEEERKKQEEQAKRQQEEEAAAQMKE 123
           E++ER +++E++   E +  K+EE    EE+++ +EEE++  EE+ + ++EE+ AA+ ++
Sbjct: 312 EERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQ 371

Query: 124 KEESIQLHQEAWERHHLRKELRSKNQNAPDSR 155
           +  + +  +   E     K+L  K     +++
Sbjct: 372 RARAEEEEKAKVEEQKRNKQLEEKKHAMQETK 403



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 59/239 (24%), Positives = 116/239 (48%), Gaps = 38/239 (15%)

Query: 4   ERKKPASMEEKD---SLPNNKEKDCSERRTVSSKERPKDDIKLTAKK-----EVSKAPED 55
           +++K    EEK    S+  N+ +   E +T  S+E   + + ++ K      E  K  E+
Sbjct: 187 DKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQE---ETVVMSLKNGQISSEEPKQEEE 243

Query: 56  KKKRLED----DKRKKEDKER--------KKKDEEKVKAEEESK------KKEEEEKKKH 97
           +++  ++    +K ++EDKER        + ++ E++KAE++ K      + E EEK   
Sbjct: 244 REQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAA 303

Query: 98  QEEERKKQEEQAKRQQEEEAAAQMKE--KEESIQLHQEAWERHHLRKELRSKNQNAPDSR 155
           QE ER++ EE+ + ++EE+ AA+ ++  KEE     + A ER  +++E +   +     +
Sbjct: 304 QERERREAEERERMREEEKRAAEERQRIKEEE---KRAAEERQRIKEEEKRAAEERQRIK 360

Query: 156 PEENFFSRLDSSLKKNTAFVKKLKTITEQQRD-SLSHDFNGLNLSKYIAEAVASIVEAK 213
            EE    R     ++  A  ++   + EQ+R+  L    + +  +K   E V   +E K
Sbjct: 361 EEE---KRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGK 416



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 46/131 (35%), Positives = 72/131 (54%), Gaps = 15/131 (11%)

Query: 47  KEVSKAPE-DKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERK-- 103
           KE   AP+ +  KRLE+ +R++ + E   ++ EK+K +++    E EE KK +EE RK  
Sbjct: 522 KEAEGAPQVEAGKRLEELRRRRGETE--SEEFEKLKQKQQEAALELEELKKKREERRKVL 579

Query: 104 KQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAP-----DSRPEE 158
           ++EEQ ++Q  EEA  +++E+EE  +L +E   R   R E   K Q  P     D +   
Sbjct: 580 EEEEQRRKQ--EEADRKLREEEEKRRLKEEIERR---RAEAAEKRQKMPEDGLSDDKKPF 634

Query: 159 NFFSRLDSSLK 169
             F+   SSLK
Sbjct: 635 KCFTPKGSSLK 645



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 59/249 (23%), Positives = 115/249 (46%), Gaps = 38/249 (15%)

Query: 3   AERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAK-KEVSKAPEDKKKRLE 61
           AE ++    EEK +    +     E+R    ++R K++ K  A+ ++ ++A E++K ++E
Sbjct: 325 AEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVE 384

Query: 62  DDKRKKEDKERK----------KKDEEKV--------KAEEES------KKKEEEEKKKH 97
           + KR K+ +E+K          +K E+K+        KA+E+       KK+ EE+  K 
Sbjct: 385 EQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKV 444

Query: 98  QEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQN--APDSR 155
           Q +  K QE++   ++EE    ++K+ +E  +  +   +R     E++S+N        +
Sbjct: 445 QAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLK 504

Query: 156 PEENFFSRLDSSLKKNTAFV---------KKLKTITEQQRDSLSHDFNGLNLSKYIAEAV 206
             EN FSR       +T            K+L+ +  ++ ++ S +F  L   +   EA 
Sbjct: 505 HTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQ--QEAA 562

Query: 207 ASIVEAKLK 215
             + E K K
Sbjct: 563 LELEELKKK 571



 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 40/172 (23%), Positives = 86/172 (50%), Gaps = 15/172 (8%)

Query: 24  DCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKA- 82
           D  E       E  K   +L  ++  +++ E +K + +  +   E +E KKK EE+ K  
Sbjct: 520 DTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVL 579

Query: 83  --EEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWE---- 136
             EE+ +K+EE ++K  +EEE+++ +E+ +R++ E A  + K  E+ +   ++ ++    
Sbjct: 580 EEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTP 639

Query: 137 -----RHHLRKELRSKN---QNAPDSRPEENFFSRLDSSLKKNTAFVKKLKT 180
                +   R E  +K+    +   S  +    S++DS L++ T+ ++  K+
Sbjct: 640 KGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKS 691



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 51/199 (25%), Positives = 90/199 (45%), Gaps = 45/199 (22%)

Query: 4   ERKK---PASMEEKDSLPNNK-EKDCSERRTVSSKERPK---DDIKLTAKKEVSKAPEDK 56
           ER+K   P   +   SLP+ + + D +E  T   +E+ +   +  ++   + V+K+ +  
Sbjct: 116 ERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKN 175

Query: 57  KKRLEDDKRKKEDKERKKKDEEKVK------------AEEESKKKEEE------------ 92
             R + ++ KKEDKE+++++EEK K             EE++ + +EE            
Sbjct: 176 DWR-DAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQIS 234

Query: 93  EKKKHQEEERK----------KQEEQAKRQQEEEAAAQMKEKEESIQLHQE---AWERHH 139
            ++  QEEER+          K EE+ K + E E A    E+ E I+  Q+   A ER  
Sbjct: 235 SEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERAR 294

Query: 140 LRKELRSKNQNAPDSRPEE 158
           +  E ++  Q       EE
Sbjct: 295 IEAEEKAAAQERERREAEE 313



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 17/66 (25%), Positives = 46/66 (69%), Gaps = 1/66 (1%)

Query: 62  DDKRKKEDKERKKKDEEKVKAEEES-KKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 120
           DD  ++ +  R+K++E +++AE  + ++ +++E++  +E  R+ ++E+ +++QEEE+  Q
Sbjct: 2   DDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQ 61

Query: 121 MKEKEE 126
           + ++ E
Sbjct: 62  VTDQVE 67



 Score = 38.9 bits (89), Expect = 0.032
 Identities = 37/166 (22%), Positives = 80/166 (48%), Gaps = 12/166 (7%)

Query: 24  DCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAE 83
           D   RR +  ++R  ++++L A++   +  +D ++    ++R++  +ER ++ +E+    
Sbjct: 3   DFERRRELRRQKR--EEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLG 60

Query: 84  EESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAA--AQMKEKEESIQLH-QEAWERHHL 140
           + + + E   +    +EE K      + + ++EAA   ++  +EE  Q   QEA ER   
Sbjct: 61  QVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALER--- 117

Query: 141 RKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQR 186
           +KE      +A  S P      R+ +   +N    K+ K+ + Q+R
Sbjct: 118 QKEFDPTITDASLSLPSR----RMQNDTAENETTEKEEKSESRQER 159



 Score = 38.1 bits (87), Expect = 0.054
 Identities = 49/242 (20%), Positives = 96/242 (39%), Gaps = 37/242 (15%)

Query: 1019 SKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEE----- 1073
            +++  TE E   E  +E     ETE  + +  + +  + EE    D ++ EEEEE     
Sbjct: 142  AENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRG 201

Query: 1074 ---ENTDYLTDSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMM-LENLQQRS 1129
               EN   +    K  E+ EE   + +K G +      ++E+  Q  D++   E +++  
Sbjct: 202  SIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEED 261

Query: 1130 GESVKVHQLDVAIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVP 1189
             E  +  +  +                     EAE  + +       +  K   +   + 
Sbjct: 262  KERAEAERARL---------------------EAEERERIK----AEQDKKIADERARIE 296

Query: 1190 MSSQLAANHWNQQQAEQEERMR-MKKLTLDINERQEQEDYQ--EMLQSLAQRPAPANTNR 1246
               + AA    +++AE+ ERMR  +K   +  +R ++E+ +  E  Q + +    A   R
Sbjct: 297  AEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEER 356

Query: 1247 ER 1248
            +R
Sbjct: 357  QR 358



 Score = 37.4 bits (85), Expect = 0.092
 Identities = 38/193 (19%), Positives = 80/193 (41%), Gaps = 22/193 (11%)

Query: 19  NNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEE 78
           +++E+   ERR  + +ER +   +  +  +V+   E   +    D+  K      + + +
Sbjct: 32  DDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGD 91

Query: 79  KVKAEEESKKKEEEEKKKHQEEERKKQEE------------QAKRQQEEEAAAQMKEKEE 126
              A  E   + EE ++K  +E  ++Q+E             ++R Q + A  +  EKEE
Sbjct: 92  DEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEE 151

Query: 127 SIQLHQEAWE--------RHHLRKELRSKNQNAPD--SRPEENFFSRLDSSLKKNTAFVK 176
             +  QE +E        + + + + R   +N  +   + EE        S+ +N   V 
Sbjct: 152 KSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVM 211

Query: 177 KLKTITEQQRDSL 189
             +  TE Q +++
Sbjct: 212 VEEKTTESQEETV 224



 Score = 35.0 bits (79), Expect = 0.46
 Identities = 28/103 (27%), Positives = 50/103 (48%), Gaps = 12/103 (11%)

Query: 1004 EREFLIKLGLVND-KDSKDSMTEGENLEEDEEEE-EGGAETEEQSGNESEVNEPEEEEGS 1061
            E E + K    ND +D++++  E +  EE+EEE+ + G+  E Q     E    E +E +
Sbjct: 164  ETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEET 223

Query: 1062 ----------DNDDDEGEEEEEENTDYLTDSNKENETDEENTE 1094
                       +++ + EEE E+ +D ++   K  E D+E  E
Sbjct: 224  VVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAE 266



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 42/238 (17%), Positives = 91/238 (38%), Gaps = 12/238 (5%)

Query: 1020 KDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYL 1079
            K+     E  +++EE E+G  E       E E  E  E E +  + +E E  + E    +
Sbjct: 229  KNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKI 288

Query: 1080 TDSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLD 1139
             D     E +E+      +    +    + +E+   A ++  ++  ++R+ E  +  + +
Sbjct: 289  ADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEE 348

Query: 1140 VAIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQL-AANH 1198
                   + +++        E E  +A+        R   +++ K+     + QL    H
Sbjct: 349  EKRAAEERQRIK--------EEEKRAAEER---QRARAEEEEKAKVEEQKRNKQLEEKKH 397

Query: 1199 WNQQQAEQEERMRMKKLTLDINERQEQEDYQEMLQSLAQRPAPANTNRERRPRYQHPK 1256
              Q+   + E++  K     +NE++ QED  +      Q        + +R + Q  K
Sbjct: 398  AMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDK 455



 Score = 30.8 bits (68), Expect = 8.6
 Identities = 25/103 (24%), Positives = 43/103 (41%), Gaps = 4/103 (3%)

Query: 460 EDEDARNFYENLIDLKAFVPAILFKDNEKSCQNKESNKDDTKEAKESKENKEVSSPDDLE 519
           E+   +   E L   K F P I   D   S  ++    D  +     KE K  S  +   
Sbjct: 104 EERRQKRLQEALERQKEFDPTIT--DASLSLPSRRMQNDTAENETTEKEEKSESRQE--R 159

Query: 520 LELENLEINDDTLELEGGDEAEDLTKKLLDEQEQEDEEASTGS 562
            E+E  E    + +     +AE+  K+  +++E+E+E+   GS
Sbjct: 160 YEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGS 202


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score = 68.6 bits (166), Expect = 4e-11
 Identities = 39/138 (28%), Positives = 83/138 (60%), Gaps = 11/138 (7%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
           R++   + E++ +   +E+   E+     +E+ ++  K+  ++E  +  E+K +  ++  
Sbjct: 533 REQEEKIREQEEMMQEQEEKMGEQ-----EEKMQEQEKMRRQEEKIREQEEKIREQKEKI 587

Query: 65  RKKEDK----ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE--EAA 118
           R++E+K    E K +++E++  E+E K  E+EEK   QEE+ ++QEE+ +RQ+E+  E  
Sbjct: 588 REQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 647

Query: 119 AQMKEKEESIQLHQEAWE 136
            +++++EE +Q HQE  E
Sbjct: 648 VRLRQQEEKMQEHQEHLE 665



 Score = 63.9 bits (154), Expect = 9e-10
 Identities = 47/181 (25%), Positives = 101/181 (55%), Gaps = 22/181 (12%)

Query: 12  EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDK- 70
           E+++ +   +EK   +   +  KE      K+  ++E+    E+K +RLE+   +KE+K 
Sbjct: 325 EQEEKIREQEEKMRRQEEMMWEKEE-----KMRRQEEMMWEKEEKMRRLEEMMWEKEEKI 379

Query: 71  -ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESI- 128
            E ++K  E+ K  E+ +K++EEEK + QE   K+QE++AK  ++EE   +++E+EE I 
Sbjct: 380 RELEEKMHEQEKIREQEEKRQEEEKIREQE---KRQEQEAKMWRQEE---KIREQEEKIR 433

Query: 129 QLHQEAW---ERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQ 185
           +  ++ W   E+ H ++++R +     + R E+    R +  +++     ++ + + EQ+
Sbjct: 434 EQEKKMWRQEEKIHEQEKIREE-----EKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQE 488

Query: 186 R 186
           +
Sbjct: 489 K 489



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 46/167 (27%), Positives = 89/167 (53%), Gaps = 13/167 (7%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
           E++K    EEK      K  D  E+     ++  + + K+  ++E  +  E+K +  E+ 
Sbjct: 486 EQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEM 545

Query: 64  KRKKEDK----ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAA 119
            +++E+K    E K +++EK++ +EE K +E+EEK + Q+E+ ++QEE+   Q+E     
Sbjct: 546 MQEQEEKMGEQEEKMQEQEKMRRQEE-KIREQEEKIREQKEKIREQEEKIWEQEE----- 599

Query: 120 QMKEKEESIQLHQE-AWERHHLRKELRSKNQNAPDS--RPEENFFSR 163
           +++E+EE +Q  +E  WE+     E   K Q   +   R EE  + +
Sbjct: 600 KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ 646



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 49/177 (27%), Positives = 95/177 (53%), Gaps = 20/177 (11%)

Query: 22  EKDCSERRTVSSKERPKDDIKLTAKK--EVSKAPEDKKKRLEDDKRKKEDKERKK----- 74
           EK+   RR        ++ I+   +K  E  K  E ++KR E++K ++++K +++     
Sbjct: 360 EKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 419

Query: 75  KDEEKVKAEEESKKKEEEEKKKHQEE---ERKKQEEQAKRQQEEEAAAQMKEKEESIQLH 131
           + EEK++ E+E K +E+E+K   QEE   E++K  E+ KRQ++EE    M  +EE I+  
Sbjct: 420 RQEEKIR-EQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEE----MWRQEEKIREQ 474

Query: 132 QEAW---ERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQ 185
           +E W   E+ H ++++R + +     R EE    + +   ++     ++ + I EQ+
Sbjct: 475 EEIWRQKEKMHEQEKIRKQEEKV--WRQEEKMHDQEEKIREQEEKMWRQEEKIREQE 529



 Score = 60.8 bits (146), Expect = 8e-09
 Identities = 43/187 (22%), Positives = 97/187 (51%), Gaps = 14/187 (7%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLE--D 62
           R++    E+++ +   ++K   +   +  +E+ +++ K   ++E+ +  E  +++ E   
Sbjct: 420 RQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR 479

Query: 63  DKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMK 122
            K K  ++E+ +K EEKV  +EE K  ++EEK + QEE+  +QEE+  R+QEE    +++
Sbjct: 480 QKEKMHEQEKIRKQEEKVWRQEE-KMHDQEEKIREQEEKMWRQEEKI-REQEE----KIR 533

Query: 123 EKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTIT 182
           E+EE I+      E+  + +E   K     +   E+    R +  +++    +++ K   
Sbjct: 534 EQEEKIR------EQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKI 587

Query: 183 EQQRDSL 189
            +Q + +
Sbjct: 588 REQEEKI 594



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 43/196 (21%), Positives = 100/196 (51%), Gaps = 17/196 (8%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPED----KKKRL 60
           R++   + E++     +E+   E+  +  +E+ ++  ++  ++E  +  E+    K+K  
Sbjct: 426 REQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMH 485

Query: 61  EDDK-RKKEDK----ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQE- 114
           E +K RK+E+K    E K  D+E+   E+E K   +EEK + QEE+ ++QEE+ + Q+E 
Sbjct: 486 EQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEM 545

Query: 115 -EEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTA 173
            +E   +M E+EE +Q      E+  +R++     +     R ++      +  + +   
Sbjct: 546 MQEQEEKMGEQEEKMQ------EQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEE 599

Query: 174 FVKKLKTITEQQRDSL 189
            +++ + + ++Q + +
Sbjct: 600 KIREQEEMMQEQEEKM 615



 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 42/160 (26%), Positives = 85/160 (53%), Gaps = 13/160 (8%)

Query: 12  EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDK- 70
           +E++ +   +EK   +      KE+  +  K+  ++E     E+K    E+  R++E+K 
Sbjct: 459 QEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKM 518

Query: 71  ----ERKKKDEEKVKAEEES-KKKEE---EEKKKHQEEERKKQEEQAKRQQEE---EAAA 119
               E+ ++ EEK++ +EE  +++EE   E+++K  E+E K QE++  R+QEE   E   
Sbjct: 519 WRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEE 578

Query: 120 QMKEKEESIQLHQE-AWERHHLRKELRSKNQNAPDSRPEE 158
           +++E++E I+  +E  WE+    +E     Q   +   E+
Sbjct: 579 KIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQ 618



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 40/131 (30%), Positives = 71/131 (54%), Gaps = 12/131 (9%)

Query: 34  KERPKDDIKLTAKKEVSKA-----PEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKK 88
           KE      KL A+ E ++       + ++K    +++ +E +E+ ++ EEK++ E+E K 
Sbjct: 272 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR-EQEEKI 330

Query: 89  KEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESI-QLHQEAWERHHLRKELRSK 147
           +E+EEK + QEE   ++EE+ +RQ+E      M EKEE + +L +  WE+    +EL  K
Sbjct: 331 REQEEKMRRQEEMMWEKEEKMRRQEE-----MMWEKEEKMRRLEEMMWEKEEKIRELEEK 385

Query: 148 NQNAPDSRPEE 158
                  R +E
Sbjct: 386 MHEQEKIREQE 396



 Score = 54.7 bits (130), Expect = 6e-07
 Identities = 32/160 (20%), Positives = 89/160 (55%), Gaps = 15/160 (9%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERP--KDDIKLTAKKEVSKAPEDK----KK 58
           R++    ++++ +   +EK   +   +  +E    + + K+  ++E+ +  E+K    ++
Sbjct: 499 RQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEE 558

Query: 59  RLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEE----EKKKHQEEERKKQEEQAKRQQE 114
           ++++ ++ +  +E+ ++ EEK++ ++E  +++EE    +++K +E+E   QE++ K  ++
Sbjct: 559 KMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQ 618

Query: 115 EEAAAQ----MKEKEESIQLHQE-AWERHHLRKELRSKNQ 149
           EE   +    M+E+EE ++  +E  WE+    ++   K Q
Sbjct: 619 EEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 658



 Score = 54.3 bits (129), Expect = 7e-07
 Identities = 47/221 (21%), Positives = 108/221 (48%), Gaps = 11/221 (4%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
           R+    M EK+      E+   E+  +  +E  + + +   ++E  +  E K  R E+  
Sbjct: 366 RRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 425

Query: 65  RKKEDKERKKKDEEKVKAEEESKKKEEE--EKKKHQEEERKKQEEQAKRQQEE--EAAAQ 120
           R++E+K R++  E+K+  +EE   ++E+  E++K QE+E   ++E+  R+QEE      +
Sbjct: 426 REQEEKIREQ--EKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK 483

Query: 121 MKEKEESIQLHQEAW---ERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKK 177
           M E+E+  +  ++ W   E+ H ++E + + Q     R EE    + +  +++    +++
Sbjct: 484 MHEQEKIRKQEEKVWRQEEKMHDQEE-KIREQEEKMWRQEEKIREQ-EEKIREQEEKIRE 541

Query: 178 LKTITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKISD 218
            + + ++Q + +      +   + +      I E + KI +
Sbjct: 542 QEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIRE 582



 Score = 54.3 bits (129), Expect = 7e-07
 Identities = 31/129 (24%), Positives = 69/129 (53%), Gaps = 5/129 (3%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
           R++   M+E++     +E+   E+  +  +E    + +   +++  K  E ++K  E ++
Sbjct: 540 REQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEE 599

Query: 65  RKKEDKERKKKDEEKVKAEEES-----KKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAA 119
           + +E +E  ++ EEK+  +EE      +K +E+E+K  ++EE+  ++E   RQQEE+   
Sbjct: 600 KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 659

Query: 120 QMKEKEESI 128
             +  E +I
Sbjct: 660 HQEHLEAAI 668



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 36/149 (24%), Positives = 78/149 (52%), Gaps = 10/149 (6%)

Query: 47  KEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQE 106
           ++  K  E ++K  E +++ +E +E+ ++ EEK++ +EE    E+EEK + QEE   ++E
Sbjct: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMW-EKEEKMRRQEEMMWEKE 362

Query: 107 EQAKRQQE---------EEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPE 157
           E+ +R +E          E   +M E+E+  +  ++  E   +R++ + + Q A   R E
Sbjct: 363 EKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 422

Query: 158 ENFFSRLDSSLKKNTAFVKKLKTITEQQR 186
           E    + +   ++     ++ + I EQ++
Sbjct: 423 EKIREQEEKIREQEKKMWRQEEKIHEQEK 451



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 38/151 (25%), Positives = 73/151 (48%), Gaps = 13/151 (8%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDK-------- 56
           ++K A ++EK  L  +++ +   +  V   +R  +  KL   ++  +A  D         
Sbjct: 220 KEKNAKLQEKLQLVESEKSEI--QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV 277

Query: 57  KKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE- 115
             +L+    + E   R  + +E+    +E K +E EEK + QEE+ ++QEE+ + Q+E+ 
Sbjct: 278 SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM 337

Query: 116 -EAAAQMKEKEESIQLHQE-AWERHHLRKEL 144
                 M EKEE ++  +E  WE+    + L
Sbjct: 338 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRL 368



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 41/174 (23%), Positives = 79/174 (45%), Gaps = 13/174 (7%)

Query: 21  KEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDK------KKRLEDDKRKKEDKERKK 74
           KEK+   +  +   E  K +I+L  K+   K    K      + + E D   KE +    
Sbjct: 220 KEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA 279

Query: 75  KDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEA 134
           K + +V+  E   +  +++++K   +E K QE + K Q++EE   +++E+EE I+  +E 
Sbjct: 280 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEE---KIREQEEKIREQEEK 336

Query: 135 WERHH---LRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQ 185
             R       KE + + Q       EE    RL+  + +    +++L+    +Q
Sbjct: 337 MRRQEEMMWEKEEKMRRQEEMMWEKEEK-MRRLEEMMWEKEEKIRELEEKMHEQ 389



 Score = 35.0 bits (79), Expect = 0.46
 Identities = 28/119 (23%), Positives = 55/119 (46%), Gaps = 8/119 (6%)

Query: 981  ELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEE---EEE 1037
            E +R + +     EE IR+ +++ +E   K+G     + ++ M E E +   EE   E+E
Sbjct: 523  EKIREQEEKIREQEEKIREQEEMMQEQEEKMG-----EQEEKMQEQEKMRRQEEKIREQE 577

Query: 1038 GGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTEVM 1096
                 +++   E E    E+EE     ++  +E+EE+  +      ++ E  +E  E M
Sbjct: 578  EKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 636



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 50/262 (19%), Positives = 111/262 (42%), Gaps = 36/262 (13%)

Query: 975  MISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEE 1034
            M+ +  E +R + ++    EE +R+++++  E   K+     ++ ++ M E E + E EE
Sbjct: 343  MMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKI-----RELEEKMHEQEKIREQEE 397

Query: 1035 ---EEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEE---EENTDYLTDSNKENET 1088
               EEE   E E++   E+++   EE+     +    +E++   +E   +  +  +E E 
Sbjct: 398  KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEK 457

Query: 1089 DEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESV-----KVHQLDVAIP 1143
             +E  E+  +   ++     E E+  +  +KM  +   ++  E V     K+H  +  I 
Sbjct: 458  RQEQEEMWRQEEKIR-----EQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIR 512

Query: 1144 LHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWNQQQ 1203
               +   R+   +   E                K  +Q+ KI       Q       +Q+
Sbjct: 513  EQEEKMWRQEEKIREQE---------------EKIREQEEKIREQEEMMQEQEEKMGEQE 557

Query: 1204 AEQEERMRMKKLTLDINERQEQ 1225
             + +E+ +M++    I E++E+
Sbjct: 558  EKMQEQEKMRRQEEKIREQEEK 579



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 29/129 (22%), Positives = 65/129 (50%), Gaps = 16/129 (12%)

Query: 21  KEKDCSE----RRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKD 76
           KE+D       R T++ +E  + + KL  K ++ ++ + + +    + ++K ++ +    
Sbjct: 200 KERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLP 259

Query: 77  EEKVKAEEESKKKEEEE---KKKHQEEE-----RKKQEEQAKRQQEEEAAAQMKEK---- 124
           +++++AE +   KE +    K + Q EE     R  Q+++ K  ++EE   + +EK    
Sbjct: 260 QQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ 319

Query: 125 EESIQLHQE 133
           EE I+  +E
Sbjct: 320 EEKIREQEE 328



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 40/190 (21%), Positives = 83/190 (43%), Gaps = 21/190 (11%)

Query: 956  KKSLEVWTKDHPFPIDIDYMISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVN 1015
            K+  +VW ++          + D  E +R + +     EE IR+ ++  RE   K+    
Sbjct: 492  KQEEKVWRQEEK--------MHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKI---- 539

Query: 1016 DKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEEN 1075
             ++ ++ M E E  E+  E+EE   E E+    E ++   E+EE      ++  E+EE+ 
Sbjct: 540  -REQEEMMQEQE--EKMGEQEEKMQEQEKMRRQEEKIR--EQEEKIREQKEKIREQEEKI 594

Query: 1076 TDYLTDSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKV 1135
             +      ++ E  +E  E M +    +     E E+ +Q  ++ M    ++   + V++
Sbjct: 595  WEQEEKIREQEEMMQEQEEKMWE----QEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRL 650

Query: 1136 HQLDVAIPLH 1145
             Q +  +  H
Sbjct: 651  RQQEEKMQEH 660



 Score = 31.2 bits (69), Expect = 6.6
 Identities = 27/109 (24%), Positives = 53/109 (48%), Gaps = 7/109 (6%)

Query: 64  KRKKEDK--ERKKKDEEKVKAE-EESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 120
           ++KK D+  E   K+ + +  E   +   +EE K+K+ + + K Q  ++++ + +    +
Sbjct: 187 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE 246

Query: 121 MKEKEESIQL----HQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLD 165
           +K K E  +L     Q   E  HL KEL+S +        E   ++RL+
Sbjct: 247 LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN 295



 Score = 31.2 bits (69), Expect = 6.6
 Identities = 28/115 (24%), Positives = 50/115 (43%), Gaps = 14/115 (12%)

Query: 994  EESIRQVQDLEREFLIKLG----LVNDKDSKDSMTEGENLEEDE----------EEEEGG 1039
            EE IR+ ++  RE   K+     ++ +K+ K    E    E++E          E+EE  
Sbjct: 320  EEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKI 379

Query: 1040 AETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTE 1094
             E EE+   + ++ E EE+   +    E E+ +E+         K  E +E+  E
Sbjct: 380  RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 434


>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
           [Homo sapiens]
          Length = 918

 Score = 68.6 bits (166), Expect = 4e-11
 Identities = 46/205 (22%), Positives = 96/205 (46%), Gaps = 25/205 (12%)

Query: 1   MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
           M  E+KK   +E+K +  + K +   E R    K + K   K   + E  +  E++ +RL
Sbjct: 591 MKEEKKK--QIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRL 648

Query: 61  -----EDDKRKKEDKERKKKDEEKVK----------AEEESKKKEEEEKKKHQEEERKKQ 105
                E+++R+ ++  +KKK+EE+ +          AE+  +++ E+E+++ +  E++++
Sbjct: 649 RWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERR 708

Query: 106 EEQAKRQQEEEAAAQMKEKEESIQLHQEAWER--------HHLRKELRSKNQNAPDSRPE 157
           E++ + Q+ + A  + + ++E +Q  +E  ER          L++EL  K +     R  
Sbjct: 709 EQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLA 768

Query: 158 ENFFSRLDSSLKKNTAFVKKLKTIT 182
           E           K  A   K   +T
Sbjct: 769 ERQLQEEQEKKAKEAAGASKALNVT 793



 Score = 64.3 bits (155), Expect = 7e-10
 Identities = 52/185 (28%), Positives = 92/185 (49%), Gaps = 13/185 (7%)

Query: 12  EEKDSLPNNKEKDCSERRTVSSKERPKDDIK--LTAKKEVSKAPEDKKKRLEDDKRKKED 69
           EE + L   K ++   RR    K + ++ ++  L A++ V +  E+KKK++E    + ++
Sbjct: 549 EEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDE 608

Query: 70  KERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKR-----QQEEEAAAQ---M 121
           K  K K+E    AEE++KKK    KK  + E R+KQEE+A+R     Q+EEE   Q    
Sbjct: 609 KTEKAKEERL--AEEKAKKK-AAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQ 665

Query: 122 KEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTI 181
           K+KEE  +  ++A E   L ++   + +       E     R +   ++    + + +  
Sbjct: 666 KKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERR 725

Query: 182 TEQQR 186
            EQ+R
Sbjct: 726 REQER 730



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 42/165 (25%), Positives = 84/165 (50%), Gaps = 5/165 (3%)

Query: 26  SERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKD-EEKVKAEE 84
           +  R    KE  K  I+    +   K  + K++RL ++K KK+   +K ++ E + K EE
Sbjct: 584 ARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE 643

Query: 85  ESKK----KEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHL 140
           E+++    ++EEE+++HQE  +KK+EE+ +R ++   A ++ E+ E  +  QE  E+   
Sbjct: 644 EARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERR 703

Query: 141 RKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQ 185
            +E R + +   + +  E    R    L+      ++ K +  Q+
Sbjct: 704 EQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQK 748



 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 57/208 (27%), Positives = 98/208 (47%), Gaps = 39/208 (18%)

Query: 14  KDSLPNNKEKDCS----ERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKED 69
           K + P   +  CS    ER+ + +  R ++  +L  +K      EDK++RLE+ K K+E+
Sbjct: 521 KRNTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQK----VEEDKRRRLEEVKLKREE 576

Query: 70  KERK----------KKDEEKVKAEEE--------SKKKEE---EEKKKHQEEERKKQEEQ 108
           + RK           K+E+K + E++         K KEE   EEK K +   +K +E +
Sbjct: 577 RLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVE 636

Query: 109 AKRQQEEEA-AAQMKEKEESIQLHQEAW------ERHHLRKELRSK---NQNAPDSRPEE 158
           A+R+QEEEA   +  ++EE  + HQE        E+  LRK   +K    Q   + R +E
Sbjct: 637 ARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQE 696

Query: 159 NFFSRLDSSLKKNTAFVKKLKTITEQQR 186
                     ++     ++ + + EQ+R
Sbjct: 697 RREQERREQERREQERREQERQLAEQER 724



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 36/165 (21%), Positives = 85/165 (51%), Gaps = 11/165 (6%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
           ER + A+  ++ +    +E+   ERR    +ER + + +   ++E  +   ++++R E +
Sbjct: 673 ERLRKAAEAKRLAEQREQERREQERR---EQERREQERREQERREQERQLAEQERRREQE 729

Query: 64  KRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEE--ERKKQEEQAKRQQEEEAAAQM 121
           + + E + ++++   +++ E+  ++ EE++KK+ Q+   ER+ QEEQ K+   +EAA   
Sbjct: 730 RLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKK--AKEAAGAS 787

Query: 122 KEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDS 166
           K    ++ +   A   +    ++  +   AP     +N+   L+S
Sbjct: 788 KALNVTVDVQSPACTSY----QMTPQGHRAPPKINPDNYGMDLNS 828



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 29/118 (24%), Positives = 56/118 (47%), Gaps = 3/118 (2%)

Query: 37  PKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKK 96
           P+  +K   K+      + K   +E ++++ E+  RK++ E+  + + E  K+   E+ K
Sbjct: 512 PRSVMKSFIKRNTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVK 571

Query: 97  HQEEERKKQEEQAK---RQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNA 151
            + EER ++  QA+    Q +EE   Q+++K   I    E  +   L +E   K   A
Sbjct: 572 LKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAA 629


>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
           [Homo sapiens]
          Length = 914

 Score = 68.6 bits (166), Expect = 4e-11
 Identities = 46/205 (22%), Positives = 96/205 (46%), Gaps = 25/205 (12%)

Query: 1   MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
           M  E+KK   +E+K +  + K +   E R    K + K   K   + E  +  E++ +RL
Sbjct: 587 MKEEKKK--QIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRL 644

Query: 61  -----EDDKRKKEDKERKKKDEEKVK----------AEEESKKKEEEEKKKHQEEERKKQ 105
                E+++R+ ++  +KKK+EE+ +          AE+  +++ E+E+++ +  E++++
Sbjct: 645 RWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERR 704

Query: 106 EEQAKRQQEEEAAAQMKEKEESIQLHQEAWER--------HHLRKELRSKNQNAPDSRPE 157
           E++ + Q+ + A  + + ++E +Q  +E  ER          L++EL  K +     R  
Sbjct: 705 EQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLA 764

Query: 158 ENFFSRLDSSLKKNTAFVKKLKTIT 182
           E           K  A   K   +T
Sbjct: 765 ERQLQEEQEKKAKEAAGASKALNVT 789



 Score = 64.3 bits (155), Expect = 7e-10
 Identities = 52/185 (28%), Positives = 92/185 (49%), Gaps = 13/185 (7%)

Query: 12  EEKDSLPNNKEKDCSERRTVSSKERPKDDIK--LTAKKEVSKAPEDKKKRLEDDKRKKED 69
           EE + L   K ++   RR    K + ++ ++  L A++ V +  E+KKK++E    + ++
Sbjct: 545 EEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDE 604

Query: 70  KERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKR-----QQEEEAAAQ---M 121
           K  K K+E    AEE++KKK    KK  + E R+KQEE+A+R     Q+EEE   Q    
Sbjct: 605 KTEKAKEERL--AEEKAKKK-AAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQ 661

Query: 122 KEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTI 181
           K+KEE  +  ++A E   L ++   + +       E     R +   ++    + + +  
Sbjct: 662 KKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERR 721

Query: 182 TEQQR 186
            EQ+R
Sbjct: 722 REQER 726



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 42/165 (25%), Positives = 84/165 (50%), Gaps = 5/165 (3%)

Query: 26  SERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKD-EEKVKAEE 84
           +  R    KE  K  I+    +   K  + K++RL ++K KK+   +K ++ E + K EE
Sbjct: 580 ARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE 639

Query: 85  ESKK----KEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHL 140
           E+++    ++EEE+++HQE  +KK+EE+ +R ++   A ++ E+ E  +  QE  E+   
Sbjct: 640 EARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERR 699

Query: 141 RKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQ 185
            +E R + +   + +  E    R    L+      ++ K +  Q+
Sbjct: 700 EQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQK 744



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 51/163 (31%), Positives = 86/163 (52%), Gaps = 25/163 (15%)

Query: 16  SLPNNKEKDCSERRT---VSSKERPKDDIKLTAKKEVS------KAPEDKKKRLEDDKRK 66
           S P +  K   +R T   +  KE+ +  ++   +KE +      K  EDK++RLE+ K K
Sbjct: 510 SAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLK 569

Query: 67  KEDKERKK-KDEEKVKAEEESKKKEEEEK------KKHQEEERKKQEEQAKRQ----QEE 115
           +E++ RK  +  E+V+  +E KKK+ E+K      K  + +E +  EE+AK++    + E
Sbjct: 570 REERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKME 629

Query: 116 EAAAQMKEKEESIQLH---QEAWERHHLRKELRSKNQNAPDSR 155
           E  A+ K++EE+ +L    QE  ER H  +EL  K +     R
Sbjct: 630 EVEARRKQEEEARRLRWLQQEEEERRH--QELLQKKKEEEQER 670



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 36/165 (21%), Positives = 85/165 (51%), Gaps = 11/165 (6%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
           ER + A+  ++ +    +E+   ERR    +ER + + +   ++E  +   ++++R E +
Sbjct: 669 ERLRKAAEAKRLAEQREQERREQERR---EQERREQERREQERREQERQLAEQERRREQE 725

Query: 64  KRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEE--ERKKQEEQAKRQQEEEAAAQM 121
           + + E + ++++   +++ E+  ++ EE++KK+ Q+   ER+ QEEQ K+   +EAA   
Sbjct: 726 RLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKK--AKEAAGAS 783

Query: 122 KEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDS 166
           K    ++ +   A   +    ++  +   AP     +N+   L+S
Sbjct: 784 KALNVTVDVQSPACTSY----QMTPQGHRAPPKINPDNYGMDLNS 824


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
           sapiens]
          Length = 570

 Score = 67.4 bits (163), Expect = 8e-11
 Identities = 46/197 (23%), Positives = 99/197 (50%), Gaps = 16/197 (8%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
           R++   M EK+      E+   E+  +  +E  + + +   ++E  +  E K  R E+  
Sbjct: 333 RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 392

Query: 65  RKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE--EAAAQMK 122
           R++E+K R   ++E++  E+E K  E+EEK   QEEE ++QEE+ +RQ+E+  E   +++
Sbjct: 393 REQEEKIR---EQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIR 449

Query: 123 EKEESIQLHQEAWERHH----------LRKELRSKNQNAPDSRPEENFFSRLDSSLKKNT 172
           E+EE I+  +E  +               +E + + Q     R EE    + +  +++  
Sbjct: 450 EQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQ-EKKIREQE 508

Query: 173 AFVKKLKTITEQQRDSL 189
             +++ + + ++Q + +
Sbjct: 509 EKIREQEEMMQEQEEKM 525



 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 35/132 (26%), Positives = 75/132 (56%), Gaps = 3/132 (2%)

Query: 12  EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE 71
           E+++ +   +EK   + + +  +E    + +   +++  K  E + K  E + + +E +E
Sbjct: 429 EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEE 488

Query: 72  RKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE--EAAAQMKEKEESIQ 129
           + ++ EEK++ E+E K +E+EEK + QEE  ++QEE+   Q+E+  E   +M+E+EE ++
Sbjct: 489 KMRRQEEKIR-EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 547

Query: 130 LHQEAWERHHLR 141
             +E      +R
Sbjct: 548 RQEEKMREQEVR 559



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 41/156 (26%), Positives = 83/156 (53%), Gaps = 14/156 (8%)

Query: 12  EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE 71
           E+++ +   +EK   +   +  +E    + +   +++  K  E +KK  E +++ +E +E
Sbjct: 401 EQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 460

Query: 72  RKKKDEEKV------KAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKE 125
             ++ EEK+        E+E+K +E+EEK + QEE+ ++QE++ + Q+E     +++E+E
Sbjct: 461 MMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEE-----KIREQE 515

Query: 126 ESIQLHQE-AWERHHLRKELRSKNQNAPDS--RPEE 158
           E +Q  +E  WE+     E   K Q   +   R EE
Sbjct: 516 EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 551



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 37/136 (27%), Positives = 78/136 (57%), Gaps = 9/136 (6%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPK---DDIKLTAKKEVSKAPEDKKKRLE 61
           R++   + E++     +E+   E+  +  ++  K    + K+  ++   +  E+K +R E
Sbjct: 435 RRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQE 494

Query: 62  DDKRKKEDK----ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE-- 115
           +  R++E K    E K +++E++  E+E K  E+EEK   QEE+ ++QEE+ +RQ+E+  
Sbjct: 495 EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMR 554

Query: 116 EAAAQMKEKEESIQLH 131
           E   +++++EE +Q H
Sbjct: 555 EQEVRLRQQEEKMQEH 570



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 45/189 (23%), Positives = 99/189 (52%), Gaps = 17/189 (8%)

Query: 12  EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDK- 70
           EEK      K ++  E+     ++  + + K+  ++E+    E+K +R E+   +KE+K 
Sbjct: 287 EEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 346

Query: 71  ---ERKKKDEEKVKAEEESKKKEEE--EKKKHQEEERKKQEEQAK-RQQEEEAAAQ---M 121
              E K  ++EK++ +EE +++EE+  E++K QE+E K   ++ K R+QEE+   Q   M
Sbjct: 347 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMM 406

Query: 122 KEKEESI-QLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKT 180
           +E+EE + +  ++ WE+    +E   K       R +E      +  +++    +++ + 
Sbjct: 407 QEQEEKMGEQEEKMWEQEEEMQEQEEK------MRRQEEKIREQEKKIREQEEKIREQEE 460

Query: 181 ITEQQRDSL 189
           + ++Q + +
Sbjct: 461 MMQEQEEKM 469



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 40/198 (20%), Positives = 100/198 (50%), Gaps = 12/198 (6%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
           + +K    EEK      K ++  E+     +   + + K+  ++E+    E+K + LE+ 
Sbjct: 293 QEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEK 352

Query: 64  KRKKE---DKERKKKDEEKVKAEEESKKKE----EEEKKKHQEEERKKQEEQAKRQQEEE 116
             ++E   ++E K+++EEK++ +E+ +++E     +E+K  ++EE+ +++E+  ++QEE+
Sbjct: 353 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEK 412

Query: 117 AAAQ---MKEKEESIQLHQEAWERHH--LRKELRSKNQNAPDSRPEENFFSRLDSSLKKN 171
              Q   M E+EE +Q  +E   R    +R++ +   +     R +E      +  + + 
Sbjct: 413 MGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQ 472

Query: 172 TAFVKKLKTITEQQRDSL 189
              + + +   ++Q + +
Sbjct: 473 EGKMCEQEAKMQEQEEKM 490



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 40/177 (22%), Positives = 92/177 (51%), Gaps = 7/177 (3%)

Query: 13  EKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKER 72
           E++ L N   +   E+     ++  + + K+  ++E  +  E+K +R E+   +KE+K R
Sbjct: 274 EENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMR 333

Query: 73  KKKD---EEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQ 129
           ++++   E++ K  E  +K  E+EK + QEE+R+++E+  ++++ +E  A+M  +EE I+
Sbjct: 334 RQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 393

Query: 130 LHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQR 186
             +E        +E   + Q       EE  + + +   ++     ++ + I EQ++
Sbjct: 394 EQEEKIR----EQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEK 446



 Score = 54.3 bits (129), Expect = 7e-07
 Identities = 43/163 (26%), Positives = 78/163 (47%), Gaps = 16/163 (9%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDK-------- 56
           ++K A ++EK  L  +++ +   +  V   +R  +  KL   ++  +A  D         
Sbjct: 208 KEKNAKLQEKLQLVESEKSEI--QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV 265

Query: 57  KKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEE 116
             +L+    + E   R  + +E+    +E K +E EEK + QEE+ ++QEE+ +RQ+E  
Sbjct: 266 SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEE-- 323

Query: 117 AAAQMKEKEESIQLHQE-AWERHHLRKELRSKNQNAPDSRPEE 158
               M EKEE ++  +E  WE+    +EL  K       R +E
Sbjct: 324 ---MMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQE 363



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 39/125 (31%), Positives = 66/125 (52%), Gaps = 8/125 (6%)

Query: 34  KERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEE 93
           KE      KL A+ E ++      ++ E+   ++E+K +++  EEK++ E+E K +E+EE
Sbjct: 260 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQER--EEKIQ-EQEEKIREQEE 316

Query: 94  KKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPD 153
           K + QEE   ++EE+ +RQ+E      M EKEE I+  +E        +E   K Q    
Sbjct: 317 KMRRQEEMMWEKEEKMRRQEE-----MMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK 371

Query: 154 SRPEE 158
            R +E
Sbjct: 372 IREQE 376



 Score = 35.4 bits (80), Expect = 0.35
 Identities = 35/156 (22%), Positives = 69/156 (44%), Gaps = 22/156 (14%)

Query: 994  EESIRQVQDLEREFLIKLGLVNDK--DSKDSMTEGENL-----EEDEEEEEGGAETEEQS 1046
            EE IR+ +++ +E   K+G   +K  + ++ M E E       E+  E+E+   E EE+ 
Sbjct: 396  EEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKI 455

Query: 1047 GNESEVNEPEEE-----EGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTEVMIKGGG 1101
              + E+ + +EE     EG   + +   +E+EE      +  +E E      E  I+   
Sbjct: 456  REQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIR--- 512

Query: 1102 LKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQ 1137
                   E E+ +Q  ++ M E  ++   +  K+ +
Sbjct: 513  -------EQEEMMQEQEEKMWEQEEKMCEQEEKMQE 541



 Score = 35.0 bits (79), Expect = 0.46
 Identities = 56/274 (20%), Positives = 109/274 (39%), Gaps = 42/274 (15%)

Query: 994  EESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEE-----EEGGAETEEQSGN 1048
            EE I++ ++  RE   K+     +  ++ M E E     +EE     EE   E EE+   
Sbjct: 301  EEKIQEQEEKIREQEEKM-----RRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHE 355

Query: 1049 ESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDE---ENTEVMIKGG---GL 1102
            + ++ E EE+   +    E E+ +E+         K  E +E   E  E+M +     G 
Sbjct: 356  QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGE 415

Query: 1103 KHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDVAIPLHLKSQLRKGPPLGGGEG- 1161
            +     E E+ +Q  ++ M    ++   +  K+ + +  I    +    +   +G  EG 
Sbjct: 416  QEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGK 475

Query: 1162 ----EAESADTMPFVMLTRKGNKQQFKIL---------NVPMSSQLAANHWNQQQ----- 1203
                EA+  +    +    +  ++Q K +            M  +     W Q++     
Sbjct: 476  MCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQ 535

Query: 1204 ----AEQEERMRMKKLTL---DINERQEQEDYQE 1230
                 EQEE+MR ++  +   ++  RQ++E  QE
Sbjct: 536  EEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569



 Score = 34.3 bits (77), Expect = 0.78
 Identities = 26/113 (23%), Positives = 51/113 (45%), Gaps = 2/113 (1%)

Query: 981  ELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGA 1040
            E +R + K     EE IR+ +++ +E   K+G    K  +      E  E+   +EE   
Sbjct: 439  EKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIR 498

Query: 1041 ETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEE--ENTDYLTDSNKENETDEE 1091
            E E++   + E    +EE   + ++   E+EE+  E  + + +  ++    EE
Sbjct: 499  EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 551



 Score = 33.9 bits (76), Expect = 1.0
 Identities = 30/133 (22%), Positives = 66/133 (49%), Gaps = 16/133 (12%)

Query: 21  KEKDCSE----RRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKD 76
           KE+D       R T++ +E  + + KL  K ++ ++ + + +    + ++K ++ +    
Sbjct: 188 KERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLP 247

Query: 77  EEKVKAEEESKKKEEEE---KKKHQEEE-----RKKQEEQAKRQQEEEAAAQMKEK---- 124
           +++++AE +   KE +    K + Q EE     R  Q+++ K  ++EE   + +EK    
Sbjct: 248 QQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQ 307

Query: 125 EESIQLHQEAWER 137
           EE I+  +E   R
Sbjct: 308 EEKIREQEEKMRR 320



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 34/176 (19%), Positives = 75/176 (42%), Gaps = 10/176 (5%)

Query: 976  ISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEE 1035
            I +  E+++ + +     EE + + ++  +E   K+    +K  +      E  E+  E+
Sbjct: 399  IREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ 458

Query: 1036 EEGGAETEEQSGN------ESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETD 1089
            EE   E EE+ G       E E    E+EE     +++  E+E++  +      ++ E  
Sbjct: 459  EEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 518

Query: 1090 EENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDVAIPLH 1145
            +E  E M +    +     E E+ +Q  ++ M    ++   + V++ Q +  +  H
Sbjct: 519  QEQEEKMWE----QEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQEH 570



 Score = 31.2 bits (69), Expect = 6.6
 Identities = 27/109 (24%), Positives = 53/109 (48%), Gaps = 7/109 (6%)

Query: 64  KRKKEDK--ERKKKDEEKVKAE-EESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 120
           ++KK D+  E   K+ + +  E   +   +EE K+K+ + + K Q  ++++ + +    +
Sbjct: 175 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE 234

Query: 121 MKEKEESIQL----HQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLD 165
           +K K E  +L     Q   E  HL KEL+S +        E   ++RL+
Sbjct: 235 LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN 283


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 42/150 (28%), Positives = 85/150 (56%), Gaps = 9/150 (6%)

Query: 6   KKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKR 65
           ++   + E++ +   +EK   + +    ++R + + K+  ++E  +  E+K  R E+  R
Sbjct: 535 RQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIR 594

Query: 66  KKEDKERKK-----KDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE--EAA 118
           ++E+K +++     K EEK++ E+E K +E+EEK + QEE+ ++QEE  + Q+E+  E  
Sbjct: 595 EQEEKRQEQEEKMWKQEEKIR-EQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQE 653

Query: 119 AQMKEKEESIQLHQEA-WERHHLRKELRSK 147
            +M E+EE +Q  +E  W +    +E   K
Sbjct: 654 EKMCEQEEKMQEQEETMWRQEEKIREQEKK 683



 Score = 63.9 bits (154), Expect = 9e-10
 Identities = 43/149 (28%), Positives = 84/149 (56%), Gaps = 6/149 (4%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
           + +K    EEK      K ++  E +    +E+ ++  ++T ++E  K  E ++K  E +
Sbjct: 603 QEEKMWKQEEKIREQEEKIQE-QEEKIREQEEKIREQEEMTQEQE-EKMGEQEEKMCEQE 660

Query: 64  KRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE--EAAAQM 121
           ++ +E +E   + EEK++ E+E K +E+EEK + QEE  ++QEE+   Q+E+  E   +M
Sbjct: 661 EKMQEQEETMWRQEEKIR-EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 719

Query: 122 KEKEESIQLHQE-AWERHHLRKELRSKNQ 149
           +E+EE ++  +E  WE+    ++   K Q
Sbjct: 720 QEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 748



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 37/136 (27%), Positives = 79/136 (58%), Gaps = 9/136 (6%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPK---DDIKLTAKKEVSKAPEDKKKRLE 61
           R++   ++E++     +E+   E+  ++ ++  K    + K+  ++E  +  E+   R E
Sbjct: 615 REQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQE 674

Query: 62  DDKRKKEDK----ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE-- 115
           +  R++E K    E K +++E++  E+E K  E+EEK   QEE+ ++QEE+ +RQ+E+  
Sbjct: 675 EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMW 734

Query: 116 EAAAQMKEKEESIQLH 131
           E   +++++EE +Q H
Sbjct: 735 EQEVRLRQQEEKMQEH 750



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 50/237 (21%), Positives = 102/237 (43%), Gaps = 23/237 (9%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLED-- 62
           R+    M E++ +   +EK   E +    ++R + + K+  ++E  +  E+K +  E   
Sbjct: 394 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKM 453

Query: 63  --------------DKRKKEDKERKKKDEEKVKAEEE-----SKKKEEEEKKKHQEEERK 103
                         ++ K++++E   + EEK+  +EE      K  E+EEK + QEE+  
Sbjct: 454 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVW 513

Query: 104 KQEEQAKRQQEE--EAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFF 161
           +QEE+ + Q+E+  E   +M  +EE I+  +E W       E     +       E+  +
Sbjct: 514 RQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMW 573

Query: 162 SRLDSSLKKNTAFVKKLKTITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKISD 218
            + +   ++     ++ + I EQ+      +       + I E    I E + KI +
Sbjct: 574 RQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIRE 630



 Score = 61.2 bits (147), Expect = 6e-09
 Identities = 46/177 (25%), Positives = 86/177 (48%), Gaps = 18/177 (10%)

Query: 4   ERKKPASMEEK-----DSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKK 58
           E +K    E+K     + +   +EK   +   +  +E  + + +    K+  K  E ++K
Sbjct: 561 EEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEK 620

Query: 59  RLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE--E 116
             E +++ +E +E+ ++ EE  + E+E K  E+EEK   QEE+ ++QEE   RQ+E+  E
Sbjct: 621 IQEQEEKIREQEEKIREQEEMTQ-EQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIRE 679

Query: 117 AAAQMKEKEESIQLHQE--------AWERHHLRKELRSKNQNAPDS--RPEENFFSR 163
              +++E+EE I+  +E         WE+     E   K Q   +   R EE  + +
Sbjct: 680 QEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ 736



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 50/177 (28%), Positives = 93/177 (52%), Gaps = 19/177 (10%)

Query: 22  EKDCSERRTVSSKERPKDDIKLTAKK--EVSKAPEDKKKRLEDDKRKKEDKERKK----- 74
           EK+   RR        ++ I+   +K  E  K  E ++KR E++K ++++K +++     
Sbjct: 374 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 433

Query: 75  KDEEKVKAEEESKKKEEEEKKKHQEE---ERKKQEEQAKRQQEEEAAAQMKEKEESIQLH 131
           + EEK++ E+E K +E+E+K   QEE   E++K  E+ KRQ++EE    M  +EE I   
Sbjct: 434 RQEEKIR-EQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEE----MWRQEEKIHEQ 488

Query: 132 QEAW---ERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQ 185
           +E W   E+ H ++E + + Q     R EE    + +   ++     ++ + I EQ+
Sbjct: 489 EEIWRQKEKMHEQEE-KIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQE 544



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 46/188 (24%), Positives = 100/188 (53%), Gaps = 24/188 (12%)

Query: 12  EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE 71
           E+++ +   +EK   +   +  KE      K+  ++E+    E+K +R E+   +KE+K 
Sbjct: 325 EQEEKIREQEEKMRRQEEMMWEKEE-----KMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 379

Query: 72  RKKKD---EEKVKAEEESKKKEEEEKKKHQEEERKKQE---EQAKRQQEE----EAAAQM 121
           R++++   E++ K  E  +K  E+EK + QEE+R+++E   EQ KRQ++E        ++
Sbjct: 380 RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 439

Query: 122 KEKEESI-QLHQEAW---ERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKK 177
           +E+EE I +  ++ W   E+ H ++++R +     + R E+    R +  + +     ++
Sbjct: 440 REQEEKIREQEKKMWRQEEKIHEQEKIREE-----EKRQEQEEMWRQEEKIHEQEEIWRQ 494

Query: 178 LKTITEQQ 185
            + + EQ+
Sbjct: 495 KEKMHEQE 502



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 39/154 (25%), Positives = 86/154 (55%), Gaps = 14/154 (9%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERP---KDDIKLTAKKEVSKAPEDKKKRLE 61
           R++   M EK+     +E+   E+     ++     + + K+  ++E+    E+K + LE
Sbjct: 338 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE 397

Query: 62  DDKRKKE---DKERKKKDEEKVKAEEESKKKE-----EEEKKKHQEEERKKQEEQAKRQQ 113
           +   ++E   ++E K+++EEK++ +E+ +++E     +EEK + QEE+ ++QE++  RQ+
Sbjct: 398 EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQE 457

Query: 114 EEEAAAQMKEKEESIQLHQEAW---ERHHLRKEL 144
           E+    +   +EE  Q  +E W   E+ H ++E+
Sbjct: 458 EKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEI 491



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 38/156 (24%), Positives = 82/156 (52%), Gaps = 11/156 (7%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
           R++    E+++     +EK   +   +  +E    + +   +++  K  E ++   E ++
Sbjct: 588 RQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEE 647

Query: 65  RKKEDKERKKKDEEKVKAEEES------KKKEEEEKKKHQEEERKKQEEQAKRQQEE--E 116
           +  E +E+  + EEK++ +EE+      K +E+E+K + QEE+ ++QEE  + Q+E+  E
Sbjct: 648 KMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 707

Query: 117 AAAQMKEKEESIQLHQEAWERHHLR---KELRSKNQ 149
              +M E+EE +Q  +E   R   +   +E+R + Q
Sbjct: 708 QEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQ 743



 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 46/187 (24%), Positives = 103/187 (55%), Gaps = 18/187 (9%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERP-KDDIKLTAKKEVSKAPEDKKKRLEDD 63
           R++    E+++ +   +EK   +   +  +E   +++ K+  ++++ +  E+K++  ED 
Sbjct: 514 RQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWE--EEKRQEQEDK 571

Query: 64  KRKKEDKERKKKD-----EEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAA 118
             ++E+K R++++     EEK++ E+E K++E+EEK   QEE+ ++QEE  K Q++EE  
Sbjct: 572 MWRQEEKIREQEEKVWRQEEKIR-EQEEKRQEQEEKMWKQEEKIREQEE--KIQEQEE-- 626

Query: 119 AQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKL 178
            +++E+EE I+  +E  +     +E +   Q       EE    + ++  ++     ++ 
Sbjct: 627 -KIREQEEKIREQEEMTQ----EQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQE 681

Query: 179 KTITEQQ 185
           K I EQ+
Sbjct: 682 KKIREQE 688



 Score = 57.8 bits (138), Expect = 7e-08
 Identities = 38/155 (24%), Positives = 85/155 (54%), Gaps = 17/155 (10%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
           R++    E ++ +   +EK   +   +  +E      K+  ++E+    E+K +R E+  
Sbjct: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEE-----KMRRQEEMMWEKEEKMRRQEEMM 358

Query: 65  RKKEDKERKKKD-----EEKVKAEEESKKKEEE-----EKKKHQEEERKKQEEQAKRQQE 114
            +KE+K R++++     EEK++ +EE   ++EE     E+K H++E+ ++QEE  KRQ+E
Sbjct: 359 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE--KRQEE 416

Query: 115 EEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQ 149
           E+   Q K +E+  ++ ++  +     +++R + +
Sbjct: 417 EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEK 451



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 44/191 (23%), Positives = 95/191 (49%), Gaps = 10/191 (5%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
           R+K    E+++ +   +EK   +   +  +E    + +    ++  K  E ++   E++K
Sbjct: 493 RQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEK 552

Query: 65  RKKEDK---ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ- 120
             +++K   E K++++E     +E K +E+EEK   QEE+ ++QEE+ +++QEE+   Q 
Sbjct: 553 MHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEK-RQEQEEKMWKQE 611

Query: 121 --MKEKEESIQLHQE---AWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFV 175
             ++E+EE IQ  +E     E     +E  ++ Q       EE    + +   ++     
Sbjct: 612 EKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMW 671

Query: 176 KKLKTITEQQR 186
           ++ + I EQ++
Sbjct: 672 RQEEKIREQEK 682



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 44/189 (23%), Positives = 98/189 (51%), Gaps = 15/189 (7%)

Query: 11  MEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDK 70
           + E++     +E    E +    +E  +   K+  ++E  +  E+K  R E+  R++E+K
Sbjct: 466 IREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEK 525

Query: 71  ERKKKDEEKVKAEEESKKKEE----EEKKKHQE----EERKKQEEQAKRQQEEEAAAQMK 122
            R++  EEK+  +EE  +++E    EE+K H++    EE K+QE++ K  ++EE   +++
Sbjct: 526 IREQ--EEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEE---KIR 580

Query: 123 EKEESIQLHQE-AWERHHLRKELRSKNQNAPDS-RPEENFFSRLDSSLKKNTAFVKKLKT 180
           E+EE +   +E   E+   R+E   K     +  R +E      +  +++    +++ + 
Sbjct: 581 EQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEE 640

Query: 181 ITEQQRDSL 189
           +T++Q + +
Sbjct: 641 MTQEQEEKM 649



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 44/187 (23%), Positives = 93/187 (49%), Gaps = 13/187 (6%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
           R++   M EK+      E+   E+  +  +E  + + +   ++E  +  E K  R E+  
Sbjct: 380 RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 439

Query: 65  RKKEDKERKKKDEEKVKAEEESKKKEEE--EKKKHQEEERKKQEEQAKRQQEE--EAAAQ 120
           R++E+K R++  E+K+  +EE   ++E+  E++K QE+E   ++E+   +QEE      +
Sbjct: 440 REQEEKIREQ--EKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEK 497

Query: 121 MKEKEESIQLHQE-AWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLK 179
           M E+EE I+  +E  W +    +E   K       R +E    R +  +++     ++ +
Sbjct: 498 MHEQEEKIRKQEEKVWRQEEKIREQEEK------IREQEEKMWRQEEKIREQEEMWREEE 551

Query: 180 TITEQQR 186
            + EQ++
Sbjct: 552 KMHEQEK 558



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 40/140 (28%), Positives = 71/140 (50%), Gaps = 16/140 (11%)

Query: 34  KERPKDDIKLTAKKEVSKA-----PEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKK 88
           KE      KL A+ E ++       + ++K    +++ +E +E+ ++ EEK++ E+E K 
Sbjct: 272 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR-EQEEKI 330

Query: 89  KEEEEKKKHQEEERKKQEEQAKRQQE---------EEAAAQMKEKEESIQLHQE-AWERH 138
           +E+EEK + QEE   ++EE+ +RQ+E               M EKEE ++  +E  WE+ 
Sbjct: 331 REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 390

Query: 139 HLRKELRSKNQNAPDSRPEE 158
              +EL  K       R +E
Sbjct: 391 EKIRELEEKMHEQEKIREQE 410



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 40/163 (24%), Positives = 85/163 (52%), Gaps = 15/163 (9%)

Query: 38  KDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKD-----EEKVKAEEESKKKEEE 92
           + + K+   +E  +  E+K +  E+  R++E+K R++++     EEK++ +EE    E+E
Sbjct: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEE-MMWEKE 362

Query: 93  EKKKHQEEERKKQEEQAKRQQE---------EEAAAQMKEKEESIQLHQEAWERHHLRKE 143
           EK + QEE   ++EE+ +RQ+E          E   +M E+E+  +  ++  E   +R++
Sbjct: 363 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 422

Query: 144 LRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQR 186
            + + Q A   R EE    + +   ++     ++ + I EQ++
Sbjct: 423 EKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEK 465



 Score = 54.7 bits (130), Expect = 6e-07
 Identities = 47/218 (21%), Positives = 103/218 (47%), Gaps = 9/218 (4%)

Query: 6   KKPASMEEKDSLPNNKEKDCSERRTVSSKERP--KDDIKLTAKKEVSKAPEDKKKRLEDD 63
           ++   + E++ +   KEK   +   +  +E    + + K+  ++E  +  E+K  R E+ 
Sbjct: 480 RQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEK 539

Query: 64  KRKKEDKERKK-KDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMK 122
            R++E+  R++ K  E+ K  EE K++E+E+K   QEE  K +E++ K  ++EE   + +
Sbjct: 540 IREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEE--KIREQEEKVWRQEEKIREQE 597

Query: 123 EKEESIQLHQEAWERHHLRKELRSKNQNAPDS--RPEENFFSRLDSSLKKNTAFVKKLKT 180
           EK +  +  ++ W++    +E   K Q   +     EE    + + + ++     ++ + 
Sbjct: 598 EKRQ--EQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 655

Query: 181 ITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKISD 218
           + EQ+      +       + I E    I E + KI +
Sbjct: 656 MCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIRE 693



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 43/193 (22%), Positives = 90/193 (46%), Gaps = 14/193 (7%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDK-------- 56
           ++K A ++EK  L  +++ +   +  V   +R  +  KL   ++  +A  D         
Sbjct: 220 KEKNAKLQEKLQLVESEKSEI--QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV 277

Query: 57  KKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE- 115
             +L+    + E   R  + +E+    +E K +E EEK + QEE+ ++QEE+ + Q+E+ 
Sbjct: 278 SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM 337

Query: 116 -EAAAQMKEKEESIQLHQE-AWERHH-LRKELRSKNQNAPDSRPEENFFSRLDSSLKKNT 172
                 M EKEE ++  +E  WE+   +R++     +     R +E      +  +++  
Sbjct: 338 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE 397

Query: 173 AFVKKLKTITEQQ 185
             + + + I EQ+
Sbjct: 398 EKMHEQEKIREQE 410



 Score = 38.5 bits (88), Expect = 0.041
 Identities = 56/259 (21%), Positives = 108/259 (41%), Gaps = 47/259 (18%)

Query: 994  EESIRQVQDLEREFLIKLGLVNDK--DSKDSMTEGENLEEDEE--EEEGGAETEEQSGNE 1049
            EE IR+ ++  RE   K+    +K  + ++   E E + E E+  EEE   E E++   +
Sbjct: 516  EEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQ 575

Query: 1050 SE-VNEPEE----EEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTEVMIKGGGLKH 1104
             E + E EE    +E    + +E  +E+EE      +  +E E   +  E  I+      
Sbjct: 576  EEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIR------ 629

Query: 1105 VPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDVAIPLHLKSQLRKGPPLGGGEGEAE 1164
                E E+ I+  ++M  E  ++   +  K+ + +  +    ++  R+   +   E    
Sbjct: 630  ----EQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQE---- 681

Query: 1165 SADTMPFVMLTRKGNKQQFKIL-NVPMSSQLAANHWNQQQ---------AEQEERMRMKK 1214
                       +K  +Q+ KI     M  +     W Q++          EQEE+MR ++
Sbjct: 682  -----------KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 730

Query: 1215 LTL---DINERQEQEDYQE 1230
              +   ++  RQ++E  QE
Sbjct: 731  EKMWEQEVRLRQQEEKMQE 749



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 29/129 (22%), Positives = 65/129 (50%), Gaps = 16/129 (12%)

Query: 21  KEKDCSE----RRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKD 76
           KE+D       R T++ +E  + + KL  K ++ ++ + + +    + ++K ++ +    
Sbjct: 200 KERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLP 259

Query: 77  EEKVKAEEESKKKEEEE---KKKHQEEE-----RKKQEEQAKRQQEEEAAAQMKEK---- 124
           +++++AE +   KE +    K + Q EE     R  Q+++ K  ++EE   + +EK    
Sbjct: 260 QQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ 319

Query: 125 EESIQLHQE 133
           EE I+  +E
Sbjct: 320 EEKIREQEE 328



 Score = 31.6 bits (70), Expect = 5.1
 Identities = 56/307 (18%), Positives = 115/307 (37%), Gaps = 29/307 (9%)

Query: 976  ISDTLELLRPKIKLCNSLEESIRQVQDL----EREFLIKLGLVNDKDSKDSMTEGENLEE 1031
            I +  E +R + +     EE +R+ +++    E +   +  ++ +K+ K    E    E+
Sbjct: 316  IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEK 375

Query: 1032 DE----------EEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTD 1081
            +E          E+EE   E EE+   + ++ E EE+   +    E E+ +E+       
Sbjct: 376  EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ 435

Query: 1082 SNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDVA 1141
              K  E +E+  E        +       E+ I   +K+  E  +Q   E  +  +    
Sbjct: 436  EEKIREQEEKIRE--------QEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE---- 483

Query: 1142 IPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKI--LNVPMSSQLAANHW 1199
              +H + ++ +       + E              K  +Q+ KI      M  Q      
Sbjct: 484  -KIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIRE 542

Query: 1200 NQQQAEQEERMRMKKLTLDINERQEQEDYQEMLQSLAQRPAPANTNRERRPRYQHPKGAP 1259
             ++   +EE+M  ++   +  +RQEQED     +   +        +E + R Q  K   
Sbjct: 543  QEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQE 602

Query: 1260 NADLIFK 1266
              + ++K
Sbjct: 603  QEEKMWK 609



 Score = 31.2 bits (69), Expect = 6.6
 Identities = 27/109 (24%), Positives = 53/109 (48%), Gaps = 7/109 (6%)

Query: 64  KRKKEDK--ERKKKDEEKVKAE-EESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 120
           ++KK D+  E   K+ + +  E   +   +EE K+K+ + + K Q  ++++ + +    +
Sbjct: 187 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE 246

Query: 121 MKEKEESIQL----HQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLD 165
           +K K E  +L     Q   E  HL KEL+S +        E   ++RL+
Sbjct: 247 LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN 295



 Score = 31.2 bits (69), Expect = 6.6
 Identities = 38/218 (17%), Positives = 86/218 (39%), Gaps = 17/218 (7%)

Query: 1020 KDSMTEGENLEEDEEE-----EEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEE 1074
            K+ M E E     +EE     EE   E EE+   + E    +EE+  + ++   EEE+  
Sbjct: 495  KEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMH 554

Query: 1075 NTDYLTDSNKENETDEE--NTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGES 1132
              + + +  K  E +++    E  I+          E E+ +   ++ + E  ++R  + 
Sbjct: 555  EQEKIWEEEKRQEQEDKMWRQEEKIR----------EQEEKVWRQEEKIREQEEKRQEQE 604

Query: 1133 VKVHQLDVAIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSS 1192
             K+ + +  I    +    +   +   E +    + M      + G +++          
Sbjct: 605  EKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQ 664

Query: 1193 QLAANHWNQQQAEQEERMRMKKLTLDINERQEQEDYQE 1230
            +     W Q++  +E+  ++++    I E++E    QE
Sbjct: 665  EQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQE 702


>gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo
           sapiens]
          Length = 1297

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 43/168 (25%), Positives = 94/168 (55%), Gaps = 21/168 (12%)

Query: 28  RRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL--EDDKRKKEDKERKKKDEEKVKAEEE 85
           R  +++KER  + ++    ++  +  E+ K++L  E  KR +E KE++++ EE+ + E+E
Sbjct: 356 RLQLANKER-SEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE 414

Query: 86  SKKKEEEEKKKHQEEERKKQEEQAKRQQEEE-AAAQMKEKEESIQ------LHQEAWERH 138
            +K++E E+++H EE+ +++EE+ + + E+E    Q++E++  ++      LH++A    
Sbjct: 415 LRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLE 474

Query: 139 HLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQR 186
           + RK+L  + Q             RL   LK+   ++  L+   ++QR
Sbjct: 475 YKRKQLEEQRQ-----------AERLQRQLKQERDYLVSLQHQRQEQR 511



 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 40/166 (24%), Positives = 87/166 (52%), Gaps = 24/166 (14%)

Query: 2   PAERKKPASMEEKDSLPNNK----EKDCSERRTVSSKERPKDDI------------KLTA 45
           P ER+    ++ KD +   K    EKD +E     S+E  +++             + T 
Sbjct: 293 PNERQ--VRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTL 350

Query: 46  KKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQE-EERKK 104
           +++  +     K+R E  +R++ ++++++ +E K +   E +K+ EE+K++ +  EE+++
Sbjct: 351 RRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQR 410

Query: 105 QEEQAKRQQEEEA----AAQMKEKEESIQL-HQEAWERHHLRKELR 145
           +E++ ++QQE E       QM+ +EE  +  H++ + R  L +E R
Sbjct: 411 REKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQR 456



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 40/174 (22%), Positives = 80/174 (45%), Gaps = 35/174 (20%)

Query: 17  LPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKK---------RLEDDKRKK 67
           L N +  +   R+ +  ++R  ++ K     E  K  E++K+         R E + RK+
Sbjct: 359 LANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQ 418

Query: 68  EDKERKKKDEEKVKAEEESKKKEEEEK--KKHQEEE----------------------RK 103
           +++E+++  EE+++ EEE ++ E E++  ++  EEE                      RK
Sbjct: 419 QEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRK 478

Query: 104 KQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKEL-RSKNQNAPDSRP 156
           + EEQ + ++ +    Q ++   S+Q HQ   +R   +K L   K   +P  +P
Sbjct: 479 QLEEQRQAERLQRQLKQERDYLVSLQ-HQRQEQRPVEKKPLYHYKEGMSPSEKP 531



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 55/265 (20%), Positives = 105/265 (39%), Gaps = 40/265 (15%)

Query: 1001 QDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQ---SGNESEVNEPEE 1057
            Q  ER+  I+L     KD  D   +    +++ E E  G+E EE+   SG  S +     
Sbjct: 292  QPNERQVRIQL-----KDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPG 346

Query: 1058 EEGSDNDDDEGEEEEEENTDYLTD---SNKENETDEENTEVMIKGGGLKHVPCVEDEDFI 1114
            E     D    +   +E ++ L       ++ E +E   +++      +    +E+    
Sbjct: 347  ESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLL-----AERQKRIEE---- 397

Query: 1115 QALDKMMLENLQQRSGESVKVHQLDVAIPLHLKSQLRKGPPLGGGEGEAESADTMPFVML 1174
            Q   +  LE  Q+R  E  K  + +     H + Q+R+       E E E      ++  
Sbjct: 398  QKEQRRRLEEQQRREKELRKQQEREQR--RHYEEQMRREEERRRAEHEQE------YIRR 449

Query: 1175 TRKGNKQQFKILNVPM--SSQLAANHWNQQQAEQEERMRMKKLTLDINERQEQEDYQEML 1232
              +  ++Q +IL   +     L   +  +Q  EQ +  R+++      + +++ DY   L
Sbjct: 450  QLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQR------QLKQERDYLVSL 503

Query: 1233 QSLAQRPAPANTNRERRPRYQHPKG 1257
            Q   Q   P     E++P Y + +G
Sbjct: 504  QHQRQEQRPV----EKKPLYHYKEG 524


>gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo
           sapiens]
          Length = 1305

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 43/168 (25%), Positives = 94/168 (55%), Gaps = 21/168 (12%)

Query: 28  RRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL--EDDKRKKEDKERKKKDEEKVKAEEE 85
           R  +++KER  + ++    ++  +  E+ K++L  E  KR +E KE++++ EE+ + E+E
Sbjct: 356 RLQLANKER-SEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE 414

Query: 86  SKKKEEEEKKKHQEEERKKQEEQAKRQQEEE-AAAQMKEKEESIQ------LHQEAWERH 138
            +K++E E+++H EE+ +++EE+ + + E+E    Q++E++  ++      LH++A    
Sbjct: 415 LRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLE 474

Query: 139 HLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQR 186
           + RK+L  + Q             RL   LK+   ++  L+   ++QR
Sbjct: 475 YKRKQLEEQRQ-----------AERLQRQLKQERDYLVSLQHQRQEQR 511



 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 40/166 (24%), Positives = 87/166 (52%), Gaps = 24/166 (14%)

Query: 2   PAERKKPASMEEKDSLPNNK----EKDCSERRTVSSKERPKDDI------------KLTA 45
           P ER+    ++ KD +   K    EKD +E     S+E  +++             + T 
Sbjct: 293 PNERQ--VRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTL 350

Query: 46  KKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQE-EERKK 104
           +++  +     K+R E  +R++ ++++++ +E K +   E +K+ EE+K++ +  EE+++
Sbjct: 351 RRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQR 410

Query: 105 QEEQAKRQQEEEA----AAQMKEKEESIQL-HQEAWERHHLRKELR 145
           +E++ ++QQE E       QM+ +EE  +  H++ + R  L +E R
Sbjct: 411 REKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQR 456



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 40/174 (22%), Positives = 80/174 (45%), Gaps = 35/174 (20%)

Query: 17  LPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKK---------RLEDDKRKK 67
           L N +  +   R+ +  ++R  ++ K     E  K  E++K+         R E + RK+
Sbjct: 359 LANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQ 418

Query: 68  EDKERKKKDEEKVKAEEESKKKEEEEK--KKHQEEE----------------------RK 103
           +++E+++  EE+++ EEE ++ E E++  ++  EEE                      RK
Sbjct: 419 QEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRK 478

Query: 104 KQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKEL-RSKNQNAPDSRP 156
           + EEQ + ++ +    Q ++   S+Q HQ   +R   +K L   K   +P  +P
Sbjct: 479 QLEEQRQAERLQRQLKQERDYLVSLQ-HQRQEQRPVEKKPLYHYKEGMSPSEKP 531



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 55/265 (20%), Positives = 105/265 (39%), Gaps = 40/265 (15%)

Query: 1001 QDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQ---SGNESEVNEPEE 1057
            Q  ER+  I+L     KD  D   +    +++ E E  G+E EE+   SG  S +     
Sbjct: 292  QPNERQVRIQL-----KDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPG 346

Query: 1058 EEGSDNDDDEGEEEEEENTDYLTD---SNKENETDEENTEVMIKGGGLKHVPCVEDEDFI 1114
            E     D    +   +E ++ L       ++ E +E   +++      +    +E+    
Sbjct: 347  ESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLL-----AERQKRIEE---- 397

Query: 1115 QALDKMMLENLQQRSGESVKVHQLDVAIPLHLKSQLRKGPPLGGGEGEAESADTMPFVML 1174
            Q   +  LE  Q+R  E  K  + +     H + Q+R+       E E E      ++  
Sbjct: 398  QKEQRRRLEEQQRREKELRKQQEREQR--RHYEEQMRREEERRRAEHEQE------YIRR 449

Query: 1175 TRKGNKQQFKILNVPM--SSQLAANHWNQQQAEQEERMRMKKLTLDINERQEQEDYQEML 1232
              +  ++Q +IL   +     L   +  +Q  EQ +  R+++      + +++ DY   L
Sbjct: 450  QLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQR------QLKQERDYLVSL 503

Query: 1233 QSLAQRPAPANTNRERRPRYQHPKG 1257
            Q   Q   P     E++P Y + +G
Sbjct: 504  QHQRQEQRPV----EKKPLYHYKEG 524


>gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo
           sapiens]
          Length = 1352

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 43/168 (25%), Positives = 94/168 (55%), Gaps = 21/168 (12%)

Query: 28  RRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL--EDDKRKKEDKERKKKDEEKVKAEEE 85
           R  +++KER  + ++    ++  +  E+ K++L  E  KR +E KE++++ EE+ + E+E
Sbjct: 356 RLQLANKER-SEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE 414

Query: 86  SKKKEEEEKKKHQEEERKKQEEQAKRQQEEE-AAAQMKEKEESIQ------LHQEAWERH 138
            +K++E E+++H EE+ +++EE+ + + E+E    Q++E++  ++      LH++A    
Sbjct: 415 LRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLE 474

Query: 139 HLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQR 186
           + RK+L  + Q             RL   LK+   ++  L+   ++QR
Sbjct: 475 YKRKQLEEQRQ-----------AERLQRQLKQERDYLVSLQHQRQEQR 511



 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 40/166 (24%), Positives = 87/166 (52%), Gaps = 24/166 (14%)

Query: 2   PAERKKPASMEEKDSLPNNK----EKDCSERRTVSSKERPKDDI------------KLTA 45
           P ER+    ++ KD +   K    EKD +E     S+E  +++             + T 
Sbjct: 293 PNERQ--VRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTL 350

Query: 46  KKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQE-EERKK 104
           +++  +     K+R E  +R++ ++++++ +E K +   E +K+ EE+K++ +  EE+++
Sbjct: 351 RRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQR 410

Query: 105 QEEQAKRQQEEEA----AAQMKEKEESIQL-HQEAWERHHLRKELR 145
           +E++ ++QQE E       QM+ +EE  +  H++ + R  L +E R
Sbjct: 411 REKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQR 456



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 55/265 (20%), Positives = 105/265 (39%), Gaps = 40/265 (15%)

Query: 1001 QDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQ---SGNESEVNEPEE 1057
            Q  ER+  I+L     KD  D   +    +++ E E  G+E EE+   SG  S +     
Sbjct: 292  QPNERQVRIQL-----KDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPG 346

Query: 1058 EEGSDNDDDEGEEEEEENTDYLTD---SNKENETDEENTEVMIKGGGLKHVPCVEDEDFI 1114
            E     D    +   +E ++ L       ++ E +E   +++      +    +E+    
Sbjct: 347  ESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLL-----AERQKRIEE---- 397

Query: 1115 QALDKMMLENLQQRSGESVKVHQLDVAIPLHLKSQLRKGPPLGGGEGEAESADTMPFVML 1174
            Q   +  LE  Q+R  E  K  + +     H + Q+R+       E E E      ++  
Sbjct: 398  QKEQRRRLEEQQRREKELRKQQEREQR--RHYEEQMRREEERRRAEHEQE------YIRR 449

Query: 1175 TRKGNKQQFKILNVPM--SSQLAANHWNQQQAEQEERMRMKKLTLDINERQEQEDYQEML 1232
              +  ++Q +IL   +     L   +  +Q  EQ +  R+++      + +++ DY   L
Sbjct: 450  QLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQR------QLKQERDYLVSL 503

Query: 1233 QSLAQRPAPANTNRERRPRYQHPKG 1257
            Q   Q   P     E++P Y + +G
Sbjct: 504  QHQRQEQRPV----EKKPLYHYKEG 524


>gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo
           sapiens]
          Length = 1360

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 43/168 (25%), Positives = 94/168 (55%), Gaps = 21/168 (12%)

Query: 28  RRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL--EDDKRKKEDKERKKKDEEKVKAEEE 85
           R  +++KER  + ++    ++  +  E+ K++L  E  KR +E KE++++ EE+ + E+E
Sbjct: 356 RLQLANKER-SEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE 414

Query: 86  SKKKEEEEKKKHQEEERKKQEEQAKRQQEEE-AAAQMKEKEESIQ------LHQEAWERH 138
            +K++E E+++H EE+ +++EE+ + + E+E    Q++E++  ++      LH++A    
Sbjct: 415 LRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLE 474

Query: 139 HLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQR 186
           + RK+L  + Q             RL   LK+   ++  L+   ++QR
Sbjct: 475 YKRKQLEEQRQ-----------AERLQRQLKQERDYLVSLQHQRQEQR 511



 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 40/166 (24%), Positives = 87/166 (52%), Gaps = 24/166 (14%)

Query: 2   PAERKKPASMEEKDSLPNNK----EKDCSERRTVSSKERPKDDI------------KLTA 45
           P ER+    ++ KD +   K    EKD +E     S+E  +++             + T 
Sbjct: 293 PNERQ--VRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTL 350

Query: 46  KKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQE-EERKK 104
           +++  +     K+R E  +R++ ++++++ +E K +   E +K+ EE+K++ +  EE+++
Sbjct: 351 RRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQR 410

Query: 105 QEEQAKRQQEEEA----AAQMKEKEESIQL-HQEAWERHHLRKELR 145
           +E++ ++QQE E       QM+ +EE  +  H++ + R  L +E R
Sbjct: 411 REKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQR 456



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 55/265 (20%), Positives = 105/265 (39%), Gaps = 40/265 (15%)

Query: 1001 QDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQ---SGNESEVNEPEE 1057
            Q  ER+  I+L     KD  D   +    +++ E E  G+E EE+   SG  S +     
Sbjct: 292  QPNERQVRIQL-----KDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPG 346

Query: 1058 EEGSDNDDDEGEEEEEENTDYLTD---SNKENETDEENTEVMIKGGGLKHVPCVEDEDFI 1114
            E     D    +   +E ++ L       ++ E +E   +++      +    +E+    
Sbjct: 347  ESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLL-----AERQKRIEE---- 397

Query: 1115 QALDKMMLENLQQRSGESVKVHQLDVAIPLHLKSQLRKGPPLGGGEGEAESADTMPFVML 1174
            Q   +  LE  Q+R  E  K  + +     H + Q+R+       E E E      ++  
Sbjct: 398  QKEQRRRLEEQQRREKELRKQQEREQR--RHYEEQMRREEERRRAEHEQE------YIRR 449

Query: 1175 TRKGNKQQFKILNVPM--SSQLAANHWNQQQAEQEERMRMKKLTLDINERQEQEDYQEML 1232
              +  ++Q +IL   +     L   +  +Q  EQ +  R+++      + +++ DY   L
Sbjct: 450  QLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQR------QLKQERDYLVSL 503

Query: 1233 QSLAQRPAPANTNRERRPRYQHPKG 1257
            Q   Q   P     E++P Y + +G
Sbjct: 504  QHQRQEQRPV----EKKPLYHYKEG 524


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 42/177 (23%), Positives = 96/177 (54%), Gaps = 3/177 (1%)

Query: 9   ASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKE 68
           A++E        +E+   E+R  +  E+ K   +     E   +PE+ ++R  + +R++E
Sbjct: 457 AAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKERERE 516

Query: 69  DKERKKKDEEKVKAEEESKKKEEE-EKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEES 127
            +  K++++E+ K  E+ +++++E EK+  +E+E++++ E+ ++Q++E+   + KEKE+ 
Sbjct: 517 KELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKE 576

Query: 128 IQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQ 184
           +Q  +E  +   L KE R K +   + R E N    ++    +N+   ++    T Q
Sbjct: 577 LQKMKEQEKECELEKE-REKLEEKIEPR-EPNLEPMVEKQESENSCNKEEEPVFTRQ 631



 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 37/175 (21%), Positives = 96/175 (54%), Gaps = 6/175 (3%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
           E ++    E++ +    K K   E+  +  K+   ++I+   +++  +  ++ +K  E +
Sbjct: 467 EEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQE 526

Query: 64  KRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEER-----KKQEEQAKRQQEEEAA 118
           + K+ +K+R+++ E++ + E+E +K+ E EK++ QE+E+     K++E++ ++ +E+E  
Sbjct: 527 REKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKE 586

Query: 119 AQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTA 173
            +++++ E ++   E  E  +L   +  +      ++ EE  F+R DS+  +  A
Sbjct: 587 CELEKEREKLEEKIEPRE-PNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEA 640



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 35/148 (23%), Positives = 79/148 (53%), Gaps = 19/148 (12%)

Query: 46  KKEVSKAPEDKKKRLEDDKRKKEDK------ERKKKDEEKVKAEEESKKKEEEEKKKHQE 99
           + E+S A E  +KR E+++R+ E++      E+ K+ +EK+   E+    EE  +++ ++
Sbjct: 452 QSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREK 511

Query: 100 EERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEEN 159
           E  +++E + +++QE E     KE+E+  +  QE  +   L KE   + +   + + E+ 
Sbjct: 512 EREREKELEKEQEQERE-----KEREKDRERQQE--KEKELEKEQEKQREMEKERKQEK- 563

Query: 160 FFSRLDSSLKKNTAFVKKLKTITEQQRD 187
                +  L++     K+L+ + EQ+++
Sbjct: 564 -----EKELERQKEKEKELQKMKEQEKE 586



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 28/142 (19%), Positives = 72/142 (50%), Gaps = 30/142 (21%)

Query: 45  AKKEVSKAPE--DKKKRLEDDKRKKEDKERKKKDEEKVKAEEESK--------------- 87
           +K++V+   E   +++R + +     ++ RK+++EE+ + EE+ K               
Sbjct: 434 SKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLG 493

Query: 88  -----------KKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWE 136
                      ++ E EK++ +E+E +K++EQ + ++ E+   + +EKE+ ++  QE  +
Sbjct: 494 ILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQE--K 551

Query: 137 RHHLRKELRSKNQNAPDSRPEE 158
           +  + KE + + +   + + E+
Sbjct: 552 QREMEKERKQEKEKELERQKEK 573



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 22/90 (24%), Positives = 46/90 (51%), Gaps = 1/90 (1%)

Query: 70  KERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQ 129
           K+R+++  E   A E ++K+ EEE+++ +E+ +    E+ KR  E+    + +   E I+
Sbjct: 446 KQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIR 505

Query: 130 LHQEAWERHHLRKELRSKNQNAPDSRPEEN 159
             +   ER    KEL  + +   +   E++
Sbjct: 506 EREREKERER-EKELEKEQEQEREKEREKD 534



 Score = 39.7 bits (91), Expect = 0.019
 Identities = 23/89 (25%), Positives = 43/89 (48%)

Query: 1010 KLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGE 1069
            KLG++  + S + + E E  +E E E+E   E E++   E E +   ++E     + E E
Sbjct: 491  KLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQE 550

Query: 1070 EEEEENTDYLTDSNKENETDEENTEVMIK 1098
            ++ E   +   +  KE E  +E  + + K
Sbjct: 551  KQREMEKERKQEKEKELERQKEKEKELQK 579



 Score = 35.4 bits (80), Expect = 0.35
 Identities = 28/117 (23%), Positives = 51/117 (43%), Gaps = 11/117 (9%)

Query: 19   NNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKR---LEDDKRKKEDKERKKK 75
            +N  +   E+R+  S   PK   +    KE  + PE+K K+   +   +  K +K  K K
Sbjct: 929  SNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKKEGFIRSSEGPKPEKVYKSK 988

Query: 76   DEEKVKAEEESKKKEEEEKK--------KHQEEERKKQEEQAKRQQEEEAAAQMKEK 124
             E +      S ++EE   +        K       K+E + ++++E E A ++ EK
Sbjct: 989  SETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTEK 1045



 Score = 34.3 bits (77), Expect = 0.78
 Identities = 44/209 (21%), Positives = 90/209 (43%), Gaps = 27/209 (12%)

Query: 339 PPSEIISPEKQQPFQNLLKEYFTSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQ 398
           PP     P +  PF +          K    D  E+    R+ +  + +  E +  R ++
Sbjct: 419 PPDRQAVPGRPGPFPS----------KQQVADEDEIWKQRRRQQSEISAAVERARKRREE 468

Query: 399 YEEFAMSYQKLLANSQSLADLLDENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDLEGGI 458
            EE  M  Q+  A ++ L  L DE +  L + +P+PEE      I    +  E + E  +
Sbjct: 469 -EERRMEEQRKAACAEKLKRL-DEKLGIL-EKQPSPEE------IREREREKEREREKEL 519

Query: 459 WEDEDARNFYENLIDLKAFVPAILFKDNEKSCQNKESNKDDTKEAKESKENKEVSSPDDL 518
            ++++     E   D +        ++ EK  + ++  + + ++ ++ ++ KE+    + 
Sbjct: 520 EKEQEQEREKEREKDRERQ------QEKEKELEKEQEKQREMEKERKQEKEKELERQKEK 573

Query: 519 ELELENLEINDDTLELEGGDEAEDLTKKL 547
           E EL+ ++  +   ELE   E E L +K+
Sbjct: 574 EKELQKMKEQEKECELE--KEREKLEEKI 600



 Score = 31.6 bits (70), Expect = 5.1
 Identities = 23/79 (29%), Positives = 42/79 (53%), Gaps = 4/79 (5%)

Query: 1020 KDSMTEGENLEEDEEEEEGGAETEEQ-SGNESEVNEPEEEEGSDNDDDEGEEEEEENT-- 1076
            + S+     L+E ++ +   AE +E  +G + EV+  E+   SD DD++G    +EN   
Sbjct: 293  RPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLNFSD-DDEQGSNSPKENNSE 351

Query: 1077 DYLTDSNKENETDEENTEV 1095
            D  + +++ NE  +E  EV
Sbjct: 352  DQGSKASENNENKKETDEV 370



 Score = 31.2 bits (69), Expect = 6.6
 Identities = 26/103 (25%), Positives = 49/103 (47%), Gaps = 1/103 (0%)

Query: 992  SLEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESE 1051
            S EE   + ++ ERE   +L    +++ ++   E +   + E+E+E   E E+Q   E E
Sbjct: 500  SPEEIREREREKEREREKELEKEQEQE-REKEREKDRERQQEKEKELEKEQEKQREMEKE 558

Query: 1052 VNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTE 1094
              + +E+E     + E E ++ +  +   +  KE E  EE  E
Sbjct: 559  RKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIE 601


>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
          Length = 843

 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 41/185 (22%), Positives = 92/185 (49%), Gaps = 8/185 (4%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
           ER++    E++      +E+D    RT   KER +D  +   +    +   D+ K     
Sbjct: 328 EREREREREKEKERERERERDRDRDRT---KERDRDRDRERDRDRDRERSSDRNKDRSRS 384

Query: 64  KRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAK-RQQEEEAAAQMK 122
           + K  D+ER+++ E + + E E +++ E E+++ +E ER++++++ + R+++EE A + +
Sbjct: 385 REKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERR 444

Query: 123 EKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTIT 182
           + E  ++  + A++      E+R + +    +R  E    R +   ++     K+LK   
Sbjct: 445 KLERKLREKEAAYQERLKNWEIRERKK----TREYEKEAEREEERRREMAKEAKRLKEFL 500

Query: 183 EQQRD 187
           E   D
Sbjct: 501 EDYDD 505



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 33/144 (22%), Positives = 73/144 (50%), Gaps = 7/144 (4%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
           ER++     E++     + +   ER     ++R +D  K   +    +   D+ +    D
Sbjct: 317 ERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSD 376

Query: 64  KRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKE 123
           + K   + R+K  + + + E E +++ E E+++ +E ER+++ E+ +R++E++     +E
Sbjct: 377 RNKDRSRSREKSRDRERERERERERERERERERERERERERERER-EREREKDKKRDREE 435

Query: 124 KEESIQLHQEAWERHHLRKELRSK 147
            EE      +A+ER  L ++LR K
Sbjct: 436 DEE------DAYERRKLERKLREK 453



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 42/168 (25%), Positives = 81/168 (48%), Gaps = 23/168 (13%)

Query: 9   ASMEEKDSLPNNKEKDCSE------------------RRTVSSKERPKDDIKLTAKKEVS 50
           A  +E DS P  K+K+  E                  +  +++ E  +D   L ++ E+S
Sbjct: 224 APSQESDSHPRKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDKRDLISR-EIS 282

Query: 51  KAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAK 110
           K   D  K+LE++K KKE + ++ + E + +  E  +++E  E+++ +E ER++++E+ +
Sbjct: 283 KF-RDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKER 341

Query: 111 RQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEE 158
            ++ E    + + KE          ER   R   RS ++N   SR  E
Sbjct: 342 ERERERDRDRDRTKERD---RDRDRERDRDRDRERSSDRNKDRSRSRE 386



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 32/179 (17%), Positives = 85/179 (47%), Gaps = 3/179 (1%)

Query: 11  MEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDK 70
           +EE+      + ++  + R    +ER ++  +   ++E  +  E +K++  + +R+++  
Sbjct: 291 LEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRD 350

Query: 71  ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQL 130
             + K+ ++ +  E  + ++ E      ++  + +E+   R++E E   + + + E  + 
Sbjct: 351 RDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERE 410

Query: 131 HQEAWERHHLRKELRSKNQNAPDSRPEENFFSR--LDSSLK-KNTAFVKKLKTITEQQR 186
            +   ER   R+  R K++       EE+ + R  L+  L+ K  A+ ++LK    ++R
Sbjct: 411 REREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRER 469



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 34/142 (23%), Positives = 73/142 (51%), Gaps = 16/142 (11%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSE-----RRTVSSKERPKDDIKLTAKKEVSKAPEDKKK 58
           ERKK    E++      + ++ ++     +  +   +  +DD K      + K   D++K
Sbjct: 468 ERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREK 527

Query: 59  RLEDDKR-KKEDKERKKKDEEKVKAE------EESKKKEEEEKKKHQ----EEERKKQEE 107
            +E D+R +K +KE  ++  +++ AE       E ++ E+E +++ Q    +E   ++EE
Sbjct: 528 EMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEE 587

Query: 108 QAKRQQEEEAAAQMKEKEESIQ 129
           + K+++EE+    M+E+EE  Q
Sbjct: 588 EEKQEKEEKREEPMEEEEEPEQ 609



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 37/186 (19%), Positives = 92/186 (49%), Gaps = 14/186 (7%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
           +R++    + + S   NK++  S  ++   +ER ++      ++E  +  E +++R  + 
Sbjct: 362 DRERDRDRDRERSSDRNKDRSRSREKS-RDRERERE-----RERERERERERERERERER 415

Query: 64  KRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKE 123
           +R++E +  ++KD+++ + E+E   ++  E++K + + R+K+    +R +  E   + K 
Sbjct: 416 EREREREREREKDKKRDREEDE---EDAYERRKLERKLREKEAAYQERLKNWEIRERKKT 472

Query: 124 KEESIQLHQEAWERHHLRKE---LRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKT 180
           +E   +  +E   R  + KE   L+   ++  D R +  ++    S+L+K     +K   
Sbjct: 473 REYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYR--GSALQKRLRDREKEME 530

Query: 181 ITEQQR 186
             E+ R
Sbjct: 531 ADERDR 536



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 38/175 (21%), Positives = 86/175 (49%), Gaps = 30/175 (17%)

Query: 5   RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKD-DIKLTAKKEVSKAPEDKKKRLEDD 63
           RK    + EK++    + K+   R    ++E  K+ + +   ++E++K  +  K+ LED 
Sbjct: 444 RKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDY 503

Query: 64  KRKKED---------KERKKKDEEKVKAEEESKKKEEEEKKKHQEE-------------E 101
              ++D         ++R +  E++++A+E  +K+E+EE ++ ++              +
Sbjct: 504 DDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQ 563

Query: 102 RKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRP 156
           R +QE + +RQ       Q+K++ ES +  +E  E+   R+E   + +  P+ +P
Sbjct: 564 RMEQEAERRRQ------PQIKQEPESEEEEEEKQEKEEKREE-PMEEEEEPEQKP 611


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 43/144 (29%), Positives = 89/144 (61%), Gaps = 15/144 (10%)

Query: 21   KEKDCSERRTVSSKERPKDDIKLTA---KKEVSKAPEDKKKRLEDDKRKKED-KERKKKD 76
            KEK  S+   V S+E   ++++      +K+ S + E++++R E+++R++E+ +E +++ 
Sbjct: 2210 KEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEER 2269

Query: 77   EEKVKAEEESKKKEEEEKKKHQEEERK----------KQEEQAKRQQEEEAAAQMKEKEE 126
            +E+ + EE+  +KEEEEKKK ++E++K          +++E+   ++E E+ +  +E+EE
Sbjct: 2270 KEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEE 2329

Query: 127  SIQLHQEA-WERHHLRKELRSKNQ 149
            S  L +E   E+  L+KE + K Q
Sbjct: 2330 SCSLEEEVDREKEILKKEKQFKLQ 2353



 Score = 64.7 bits (156), Expect = 5e-10
 Identities = 46/188 (24%), Positives = 105/188 (55%), Gaps = 10/188 (5%)

Query: 6    KKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKR 65
            ++   +EE++ +P  K +   +R+     ++PK+  K +++ +  ++ E   + +E    
Sbjct: 2179 EEEGGIEEEEVIPFLKRR-WRKRKEAKRGDKPKE--KFSSQVDEVESEEHFSEEMESLLD 2235

Query: 66   KKEDKERKKKDEEKVKAEEESKKKEE-EEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEK 124
            + E +E    +EE+ + EEE +++EE  E+++ ++EE + +E+Q ++++EE+   + ++K
Sbjct: 2236 ELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKK 2295

Query: 125  EESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFS-RLDSSLKKNTAFVKKLK--TI 181
            +E +Q  +E +E    ++E+ S+ +    S  EE   S  L+  + +    +KK K   +
Sbjct: 2296 KEEVQEKEEVFEE---KEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKL 2352

Query: 182  TEQQRDSL 189
             EQ+R SL
Sbjct: 2353 QEQRRKSL 2360



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 52/209 (24%), Positives = 107/209 (51%), Gaps = 25/209 (11%)

Query: 32   SSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE------RKKKDEEKVKAEEE 85
            S +++ KD+ ++T ++EVS+  E+K++++ +++R  +++       RK+   EK +A+EE
Sbjct: 1533 SKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEE 1592

Query: 86   SKKKEEEEKKKHQE-----EERKKQEEQAKRQQEEEAAAQMK----EKEESI-----QLH 131
             K  +EEEK   +E     EERK  +   K  Q++   AQ +    +KEE++     +L 
Sbjct: 1593 RKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLS 1652

Query: 132  QEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQRDSLSH 191
            QEA +    RK+L  K +    +R EE    +     +      +K++ + +++++    
Sbjct: 1653 QEAEKLAQKRKKLAKKWEKV--AREEEKLAKKGGKLAEVKNILAQKVEELPQREQNL--- 1707

Query: 192  DFNGLNLSKYIAEAVASIVEAKLKISDVN 220
            D+    L++ + E    + E   K  ++N
Sbjct: 1708 DWQEKELAQELEELEWDMEELSWKEEELN 1736



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 47/180 (26%), Positives = 94/180 (52%), Gaps = 16/180 (8%)

Query: 4    ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
            E+++  S EE++     +E+   E   V  +E  + + +   +K+V K  E+KKK+ ++ 
Sbjct: 2238 EKQESLSSEEEEEREEEEER---EEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEK 2294

Query: 64   KRKK-EDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMK 122
            K+++ ++KE   +++E++ +EEE++   +EE    +EEE    EE+  R++E      + 
Sbjct: 2295 KKEEVQEKEEVFEEKEEIMSEEETESLSDEE----EEEESCSLEEEVDREKE------IL 2344

Query: 123  EKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKK--NTAFVKKLKT 180
            +KE+  +L ++  +    R+ + S  +  P  +        L S LKK  +TA   K KT
Sbjct: 2345 KKEKQFKLQEQRRKSLRGRERVLSILRGVPHGKGRAIRLGVLKSPLKKLMSTALEMKEKT 2404



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 49/182 (26%), Positives = 95/182 (52%), Gaps = 26/182 (14%)

Query: 27   ERRTVSSKER-PKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKED------KERKKKDEEK 79
            E+R +  +E+  +   KL+ ++E+ +  EDKK + E+ K+  E+      KE++ KDEE+
Sbjct: 1486 EKRLLQEEEKLHQAGEKLSPEEEMLQ--EDKKLKWEEWKQVWENMLSSKSKEQQYKDEEE 1543

Query: 80   VKAEEESKKKEEEEKKKHQEEERKKQEE-------------QAKRQQEEEAAAQMKEK-- 124
            V  EEE  ++ EE++++  EE+R  QEE             + KR QEE   AQ +EK  
Sbjct: 1544 VTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLA 1603

Query: 125  EESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQ 184
            +E  QL QE  ER   +  ++    +   ++ E  F  + ++  ++     ++ + + ++
Sbjct: 1604 QEERQLAQE--ERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQK 1661

Query: 185  QR 186
            ++
Sbjct: 1662 RK 1663



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 46/189 (24%), Positives = 86/189 (45%), Gaps = 16/189 (8%)

Query: 12   EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE 71
            +++  L    EK   E   ++ K     ++K    ++V + P+ ++     +K   ++ E
Sbjct: 1660 QKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELE 1719

Query: 72   RKKKDEEKVKAEEESKKKEE----EEKKKHQEEE-------RKKQEEQAKRQQEEEAAAQ 120
              + D E++  +EE   +EE    EEKKK  EEE        K  EE+ K  QEEE   Q
Sbjct: 1720 ELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQ 1779

Query: 121  MKEK--EESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKL 178
             KEK  +   ++ +E       R++L  K       R  E + + ++  L KN   + + 
Sbjct: 1780 EKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKR--ERWINSME-ELTKNKMILYQK 1836

Query: 179  KTITEQQRD 187
            K + +++++
Sbjct: 1837 KNLAQEKKN 1845



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 111/570 (19%), Positives = 226/570 (39%), Gaps = 79/570 (13%)

Query: 3    AERKKPASMEEKDSLPNNKEKDC--SERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
            A+ KK  + +EK+ L   KE      ER T S K+  +   KL    ++    E+K  + 
Sbjct: 1840 AQEKKNLA-QEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQE 1898

Query: 61   EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 120
            ++   KK++K   + +++ V+ E+   KK+E+  ++  +   +K   Q K++   E    
Sbjct: 1899 KETVIKKKEK-LAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIA 1957

Query: 121  MKEKEESIQLHQEAWERHHL--RKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKL 178
             +EK  ++++ + A E+  L   KE  SK +    SR  +   ++++  L     F +KL
Sbjct: 1958 KEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRK--MTQVEQEL-----FERKL 2010

Query: 179  KTITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKISDVNCAVHLCSLFHQRYADFAP 238
                  +   L H+       + +A   + I + KL+ +          +F Q     A 
Sbjct: 2011 SL----EEKILLHE------DRILAMEESEIAKGKLEFTRGQ------RIFVQGQRKLAK 2054

Query: 239  SLLQVWKKHFEARKEEKTPN-----ITKLRTDLRFIAELTIV------GIFTDKEGLSLI 287
            +  ++ KK     KE    N     + KL  D R + +  I        +F  +  LS+ 
Sbjct: 2055 ASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIE 2114

Query: 288  YEQLK----NIINADRESHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKFNLSFPPSEI 343
              +L     +      E       +    R   + +  ++ ++ K   E+  L+   SE+
Sbjct: 2115 QSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEV 2174

Query: 344  ISPEKQQPFQNLLKEYFTSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQYEEFA 403
            I  ++++    + +E      K   R  +E +  ++   +      E+  + H     F+
Sbjct: 2175 ILDDEEE--GGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEH-----FS 2227

Query: 404  MSYQKLLANSQSLADLLDENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDLEGGIWEDED 463
               + LL   +    L  E   +  +++   EE                     + E+E+
Sbjct: 2228 EEMESLLDELEKQESLSSEEEEEREEEEEREEEE--------------------VREEEE 2267

Query: 464  ARNFYENLIDLKAFVPAILFKDNEKSCQNKESNKDDTKEAKESKENKEVSSPDDLELELE 523
             R   E     +     +  ++ EK  + KE  K++ +E +E  E KE    ++    L 
Sbjct: 2268 ERKEEE-----EGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLS 2322

Query: 524  NLEINDDTLELEGGDEAEDLTKKLLDEQEQ 553
            + E  +++  LE   E  D  K++L +++Q
Sbjct: 2323 DEEEEEESCSLE---EEVDREKEILKKEKQ 2349



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 129/598 (21%), Positives = 231/598 (38%), Gaps = 81/598 (13%)

Query: 1    MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPK--DDIKLT---AKKEVSKAPED 55
            M  E ++ A++EEK  +   + K     RT S ++  K  D+ K      +K      E+
Sbjct: 1427 MSEEVEEMATLEEK--VVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEE 1484

Query: 56   KKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQ-- 113
             +KRL  ++ K      K   EE++  E++  K EE ++        K +E+Q K ++  
Sbjct: 1485 WEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEV 1544

Query: 114  --EEEAAAQMKEKEESI---QLH---QEAWERHHLRKELRSKNQNAPDSR---PEENFFS 162
              EEE + + +EKE+ +   Q H   +  W R H RK  R++ + A + R    EE   +
Sbjct: 1545 TLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIH-RKRARAEKKRAQEERKLAQEEEKLA 1603

Query: 163  RLDSSL-----KKNTAFVKKLKTITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKIS 217
            + +  L     K   A+VK    IT+  R+    +          A+   ++ +   K+S
Sbjct: 1604 QEERQLAQEERKLAQAYVK----ITQDDREMAQAEGK-------FAQKEETLAQRGEKLS 1652

Query: 218  DVNCAVHLCSLFHQRYADFAPSLLQVWKKHFEARKEEKTPNITKLRTDLRFIAELTIVGI 277
                         ++ A     L + W+K   AR+EEK         +++ I    +  +
Sbjct: 1653 QE----------AEKLAQKRKKLAKKWEK--VAREEEKLAKKGGKLAEVKNILAQKVEEL 1700

Query: 278  FTDKEGLSLIYEQLKNIINADRESHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKFNLS 337
               ++ L     Q K +     E    +  +         +   LV  K K A E+  L+
Sbjct: 1701 PQREQNLDW---QEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALA 1757

Query: 338  FPPSEIISPE-KQQPFQNLLKEYFTSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRH 396
            +   ++   E K    + LL +    L +H ++   E +   R+  +++  K +L++ R 
Sbjct: 1758 WQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKR- 1816

Query: 397  KQYEEFAMSYQKLLANSQSLADL--LDENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDL 454
               E +  S ++L  N   L     L +   +L Q+K    +                  
Sbjct: 1817 ---ERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQR----------------K 1857

Query: 455  EGGIWEDEDARNFYENLIDLK---AFVPAILFKDNEKSCQNKESNKDDTKEAKESKENKE 511
            E  ++  E   +  + L+ +K        IL +  EK  Q KE+     KE     E K 
Sbjct: 1858 ENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKET-VIKKKEKLAETEKKL 1916

Query: 512  VSSPDDLELELENLEINDDTLELEGGDEAEDLTKKLLDEQEQEDEEASTGSHLKLIVD 569
            V   D L  + E L      L LE         K+L  E +   EE +    +K + +
Sbjct: 1917 VQVEDSLAKKQEKLAQEKMKLALE--KAMVQGKKRLRGELDIAKEEKALNLEMKRLAE 1972



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 139/627 (22%), Positives = 247/627 (39%), Gaps = 134/627 (21%)

Query: 12   EEKDSLPNNKEK-DCSERRTVSSKERPKDDIKLTAKKEVS------KAPEDKKKRLEDDK 64
            ++ + LP  ++  D  E+      E  + D++  + KE        K  E+KKK  E+++
Sbjct: 1695 QKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEE 1754

Query: 65   RKKEDKERKKKDEEKVKAEEESKKKEEEEKKKH-----QEEER----------KKQEEQA 109
                 +E+  ++E K+  EEE   +E+E+  +H     +EEER          KK +   
Sbjct: 1755 ALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQ 1814

Query: 110  KRQ-----------------------QEEEAAAQMKEK----EESIQLHQEAWERHHLRK 142
            KR+                       QE++  AQ KEK    +E++  ++E    H  ++
Sbjct: 1815 KRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERL-THSKKQ 1873

Query: 143  ELRSKNQ----NAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQRDSLSHDFNGLNL 198
             ++ KN+    N   ++ EE      ++ +KK     +  K +  Q  DSL+     L  
Sbjct: 1874 LVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLV-QVEDSLAKKQEKLAQ 1932

Query: 199  SKYIAEAVASIVEAKLKIS---DVNCAVHLCSLFHQRYADFAPSLLQVWKKHFEARKEEK 255
             K       ++V+ K ++    D+       +L  +R A+    L++      E   + +
Sbjct: 1933 EKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVE----GKETLSKGE 1988

Query: 256  TPNITKLRTDLRFIAELTIVGIFTDKEGLSLIYEQLKNIINADR----ESHTHVSVVISF 311
            TP  ++ R   +   EL     F  K  L     + K +++ DR    E        + F
Sbjct: 1989 TPETSRQRKMTQVEQEL-----FERKLSL-----EEKILLHEDRILAMEESEIAKGKLEF 2038

Query: 312  CRHCGDDIAGLVPRKVKSAAEKFNLSFPPSEIISPEKQQPFQNLLKEYFTSLTKHLKRDH 371
             R  G  I     RK+  A+ K        E +S E  +     L +   +L K L RD 
Sbjct: 2039 TR--GQRIFVQGQRKLAKASRKL---IKKRESLSKEPAK-----LNKILKALQK-LTRDE 2087

Query: 372  RELQNTE-------------RQNRRILHSKGELSE-DRHKQYEEFAMSYQKLLANSQSLA 417
            R+L   E              +   I  SK ++ E D  ++  E     +KL    + LA
Sbjct: 2088 RKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLA 2147

Query: 418  DLLDENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDL----EGGIWEDEDARNFYENLID 473
            + +   +    ++K T EE           K  E  L    EGGI E+E           
Sbjct: 2148 NKMRRMIN--KEEKMTEEESK------LARKHSEVILDDEEEGGIEEEE----------- 2188

Query: 474  LKAFVPAILFKDNEKSCQNKESNKDDTKEAKESKENKEVSSPDDLELELENL--EI-NDD 530
                +P +      +  + KE+ + D  + K S +  EV S +    E+E+L  E+   +
Sbjct: 2189 ---VIPFL----KRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQE 2241

Query: 531  TLELEGGDEAEDLTKKLLDEQEQEDEE 557
            +L  E  +E E+  ++  +E  +E+EE
Sbjct: 2242 SLSSEEEEEREEEEEREEEEVREEEEE 2268



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 36/131 (27%), Positives = 57/131 (43%), Gaps = 20/131 (15%)

Query: 984  RPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETE 1043
            +PK K  + ++E +   +    E    L  +  ++S  S  E E  EE+E EEE   E E
Sbjct: 2208 KPKEKFSSQVDE-VESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEE 2266

Query: 1044 EQ-----SGNESEVNEPEEEEGSDNDDDEGEEEEE--------------ENTDYLTDSNK 1084
            E+      G E +V + EEE+     + + EE +E              E T+ L+D  +
Sbjct: 2267 EERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEE 2326

Query: 1085 ENETDEENTEV 1095
            E E+     EV
Sbjct: 2327 EEESCSLEEEV 2337



 Score = 40.0 bits (92), Expect = 0.014
 Identities = 40/149 (26%), Positives = 71/149 (47%), Gaps = 19/149 (12%)

Query: 955  WKKSLEVWTKDHP---FPIDIDYM-----ISDTLELLRPKIKLCNSL--EESIRQVQDLE 1004
            W+K  E    D P   F   +D +      S+ +E L  +++   SL  EE   + ++ E
Sbjct: 2197 WRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEE 2256

Query: 1005 REFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNE----SEVNEPEEEEG 1060
            RE   +  +  +++ +    EGE  + ++EEEE   + +E+   E     EV E +EE  
Sbjct: 2257 RE---EEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIM 2313

Query: 1061 SDNDDD--EGEEEEEENTDYLTDSNKENE 1087
            S+ + +    EEEEEE+     + ++E E
Sbjct: 2314 SEEETESLSDEEEEEESCSLEEEVDREKE 2342



 Score = 39.7 bits (91), Expect = 0.019
 Identities = 23/86 (26%), Positives = 46/86 (53%), Gaps = 1/86 (1%)

Query: 1014 VNDKDSKDSMTEG-ENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEE 1072
            V++ +S++  +E  E+L ++ E++E  +  EE+   E E  E EE    + +  E EE E
Sbjct: 2217 VDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGE 2276

Query: 1073 EENTDYLTDSNKENETDEENTEVMIK 1098
            E+  +   +  K+ + +++  EV  K
Sbjct: 2277 EKQVEKEEEEKKKKKKEKKKEEVQEK 2302



 Score = 37.4 bits (85), Expect = 0.092
 Identities = 27/109 (24%), Positives = 49/109 (44%), Gaps = 1/109 (0%)

Query: 1016 DKDSKDSMTEGENLEEDEE-EEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEE 1074
            DK  +   ++ + +E +E   EE  +  +E    ES  +E EEE   + + +E E  EEE
Sbjct: 2207 DKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEE 2266

Query: 1075 NTDYLTDSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLE 1123
                  +  +E + ++E  E   K    K     E E+  +  +++M E
Sbjct: 2267 EERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSE 2315



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 37/136 (27%), Positives = 60/136 (44%), Gaps = 7/136 (5%)

Query: 38   KDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKH 97
            K+  K   KK   K+P+  +K ++ + RK    +R+   EE+  +EE  +    EEK   
Sbjct: 1385 KEISKKEEKKTFQKSPKQGRKAVQKE-RKVGKIKREMTKEERDMSEEVEEMATLEEKVVK 1443

Query: 98   QEEERKKQEEQAKRQQEEEAAAQMK----EKEESIQLHQEAWERHHLRKELRSKNQNAPD 153
            QE +    E     Q  ++A  + K    E  +S +  +E WE+  L++E    +Q    
Sbjct: 1444 QEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEKRLLQEE-EKLHQAGEK 1502

Query: 154  SRPEENFFSRLDSSLK 169
              PEE      D  LK
Sbjct: 1503 LSPEEEMLQE-DKKLK 1517



 Score = 36.2 bits (82), Expect = 0.21
 Identities = 38/163 (23%), Positives = 65/163 (39%), Gaps = 52/163 (31%)

Query: 975  MISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEE 1034
            +  D  +L R + KL N +   I + + +  E           +SK +    E + +DEE
Sbjct: 2132 LTKDEKKLARKQRKLANKMRRMINKEEKMTEE-----------ESKLARKHSEVILDDEE 2180

Query: 1035 EEEGGAETEE---------------QSGNE------SEVNEPEEEEG------------- 1060
            E  GG E EE               + G++      S+V+E E EE              
Sbjct: 2181 E--GGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELE 2238

Query: 1061 -----SDNDDDEGEEEEEENTDYLTDSNKENETDEENTEVMIK 1098
                 S  +++E EEEEE   + + +  +E + +EE  E  ++
Sbjct: 2239 KQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVE 2281



 Score = 31.6 bits (70), Expect = 5.1
 Identities = 33/138 (23%), Positives = 59/138 (42%), Gaps = 21/138 (15%)

Query: 11   MEEKDSLPNNKEKDCSERRTVSSKERPKDDIK------------LTAKKEVSKAPEDKKK 58
            +  K+ +P  +E+   + R +   E  +  +K            +T  KE+SK  E K  
Sbjct: 1337 IRHKEVMPREEEQAQKKARDMLGLEETQVILKKGKKVIFLEPGNVTMGKEISKKEEKKTF 1396

Query: 59   RLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAA 118
            +    K  K+ ++  +K+ +  K + E  K  EE     + EE    EE+  +Q   E  
Sbjct: 1397 Q----KSPKQGRKAVQKERKVGKIKREMTK--EERDMSEEVEEMATLEEKVVKQ---EGK 1447

Query: 119  AQMKEKEESIQLHQEAWE 136
              M E+  S Q  ++AW+
Sbjct: 1448 LVMIERTPSWQDWKKAWD 1465


>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
          Length = 749

 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 48/196 (24%), Positives = 97/196 (49%), Gaps = 18/196 (9%)

Query: 2   PAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLE 61
           PA    PA +    S P++     +  +T +    P++  +L A+K   +   +++++ E
Sbjct: 445 PAPVPTPAMV----SAPSSTVNASASVKTSAGTTDPEEATRLLAEKR--RLAREQREKEE 498

Query: 62  DDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQE------- 114
            ++R++E+ ER+K++E   +  EE   + EEE ++ + E+ +++EEQ +RQ E       
Sbjct: 499 RERREQEELERQKREELAQRVAEERTTRREEESRRLEAEQAREKEEQLQRQAEERALRER 558

Query: 115 EEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAF 174
           EEA    ++KEE  ++ +EA     +R+E     Q     R E     RL+  +K+    
Sbjct: 559 EEAERAQRQKEEEARVREEA---ERVRQEREKHFQREEQERLERK--KRLEEIMKRTRRT 613

Query: 175 VKKLKTITEQQRDSLS 190
               K  ++Q+   ++
Sbjct: 614 EATDKKTSDQRNGDIA 629



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 24/96 (25%), Positives = 56/96 (58%), Gaps = 3/96 (3%)

Query: 19  NNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEE 78
           +++++   ERR    K+    +I    ++E  +A +  +K LE+ K++ E+ +R+K++  
Sbjct: 64  DDRQRLARERREEREKQLAAREIVWLEREE--RARQHYEKHLEERKKRLEE-QRQKEERR 120

Query: 79  KVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQE 114
           +   EE+ +++ EE+K++H+   R+  E   K +Q+
Sbjct: 121 RAAVEEKRRQRLEEDKERHEAVVRRTMERSQKPKQK 156



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 38/122 (31%), Positives = 58/122 (47%), Gaps = 21/122 (17%)

Query: 35  ERPKDDIKLTAKKEVSKAPE---------------DKKKRLEDDKRKKEDKERKKKDEEK 79
           E   D  K+  KK  S  P                D    L  D R++  +ER+++ E++
Sbjct: 21  ETAPDSYKVQDKKNASSRPASAISGQNNNHSGNKPDPPPVLRVDDRQRLARERREEREKQ 80

Query: 80  VKAEEESKKKEEEEKKKHQE---EERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWE 136
           + A E    + EE  ++H E   EERKK+ E+ +RQ+EE   A ++EK    Q  +E  E
Sbjct: 81  LAAREIVWLEREERARQHYEKHLEERKKRLEE-QRQKEERRRAAVEEKRR--QRLEEDKE 137

Query: 137 RH 138
           RH
Sbjct: 138 RH 139



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 23/96 (23%), Positives = 52/96 (54%), Gaps = 3/96 (3%)

Query: 55  DKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEE---EEKKKHQEEERKKQEEQAKR 111
           D ++RL  ++R++ +K+   ++   ++ EE +++  E   EE+KK  EE+R+K+E +   
Sbjct: 64  DDRQRLARERREEREKQLAAREIVWLEREERARQHYEKHLEERKKRLEEQRQKEERRRAA 123

Query: 112 QQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSK 147
            +E+      ++KE    + +   ER    K+  ++
Sbjct: 124 VEEKRRQRLEEDKERHEAVVRRTMERSQKPKQKHNR 159



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 24/95 (25%), Positives = 49/95 (51%), Gaps = 3/95 (3%)

Query: 33  SKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEE 92
           ++ER ++  K  A +E+     +++ R   +K  +E   RKK+ EE+ + EE  +   EE
Sbjct: 70  ARERREEREKQLAAREIVWLEREERARQHYEKHLEE---RKKRLEEQRQKEERRRAAVEE 126

Query: 93  EKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEES 127
           ++++  EE++++ E   +R  E     + K    S
Sbjct: 127 KRRQRLEEDKERHEAVVRRTMERSQKPKQKHNRWS 161


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 64.7 bits (156), Expect = 5e-10
 Identities = 49/174 (28%), Positives = 80/174 (45%), Gaps = 20/174 (11%)

Query: 4    ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDK---KKRL 60
            E  K A  E+  + P  +EK  S++     KE PK  ++   +  V K  E K   KK  
Sbjct: 837  EPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEE 896

Query: 61   EDDKRK--------------KEDKERKKKDEEKVKAEEESKKKEEEE--KKKHQEEERKK 104
             +DK+K              KED + K+K E   K  +++K KE  +  +KK    E+K 
Sbjct: 897  AEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKD 956

Query: 105  QEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEE 158
             +E+  ++ EE+   + K KE+   L +E   +    K  +S + +  DS+P E
Sbjct: 957  TKEEKAKKPEEKPKTEAKAKEDDKTLSKEP-SKPKAEKAEKSSSTDQKDSKPPE 1009



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 47/162 (29%), Positives = 75/162 (46%), Gaps = 9/162 (5%)

Query: 4   ERKKPASMEEKDSLPNNKEKDCSE-RRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLED 62
           E K PA  E +       EK  S  +  V S E+ K  +K  AK    + P  KK+ ++ 
Sbjct: 765 EAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIP--KKEEVKS 822

Query: 63  DKRKKEDKERKKKDEEKVKAEEESKKK--EEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 120
             +++E  +  K  E   KAEEE      + EEKK  ++EE  K+E    + +E++  A 
Sbjct: 823 PVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAV 882

Query: 121 MKEKEESIQLHQEAWERHHL----RKELRSKNQNAPDSRPEE 158
            K KE  ++  +E  E         KE  +K +   D++P+E
Sbjct: 883 EKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKE 924



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 41/138 (29%), Positives = 67/138 (48%), Gaps = 20/138 (14%)

Query: 4    ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERP-------KDDIKLTAKKEVSKAPEDK 56
            E+K+PA  + K+S    K+++  +++ V + E+        K+D K   K EV+K   D 
Sbjct: 876  EKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDD 935

Query: 57   KKRLEDDK---------RKKEDKERK-KKDEEKVKAEEESKKKEEEEKKKHQEEERKKQE 106
             K  E  K          KK+ KE K KK EEK K E ++K   E++K   +E  + K E
Sbjct: 936  AKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAK---EDDKTLSKEPSKPKAE 992

Query: 107  EQAKRQQEEEAAAQMKEK 124
            +  K    ++  ++  EK
Sbjct: 993  KAEKSSSTDQKDSKPPEK 1010



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 48/205 (23%), Positives = 90/205 (43%), Gaps = 8/205 (3%)

Query: 2   PAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDK----K 57
           P + K P   E K   P   +    E      KE PK +   +  KE  K  E K     
Sbjct: 782 PEKAKSPVKEEVKS--PEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPP 839

Query: 58  KRLEDDKRKKEDKERKKKDEEKVKA-EEESKKKEEEEKKKHQEEERKKQEEQAKRQQ-EE 115
           K+ E++K     K  +KKD +K +A ++E+ K + EEKK+   E+ K+ + +AK+++ E+
Sbjct: 840 KKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAED 899

Query: 116 EAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFV 175
           +      EKE   ++  +   +   + E+  K  +   ++       + +++ +K     
Sbjct: 900 KKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKE 959

Query: 176 KKLKTITEQQRDSLSHDFNGLNLSK 200
           +K K   E+ +       +   LSK
Sbjct: 960 EKAKKPEEKPKTEAKAKEDDKTLSK 984



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 49/201 (24%), Positives = 87/201 (43%), Gaps = 15/201 (7%)

Query: 2   PAERKKPASMEEKDSLPNNKEKDCSERRT---VSSKERPKDDIKLTAKKEV-SKAPEDKK 57
           P + K PA  EE  S P  K  +  E ++   V S E+ K   K  AK    +K+PE  K
Sbjct: 547 PEKAKSPAK-EEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAK 605

Query: 58  KRLEDDKRKKEDKERKKKDEEKVKAEEESKKK---------EEEEKKKHQEEERKKQEEQ 108
             ++++ +   + +   K+E K  AE +S +K         +  EK K  E+E  K  E+
Sbjct: 606 SPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEK 665

Query: 109 AKRQQEEEAAAQMKEKEE-SIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSS 167
           AK   + EA +  K K     +       +  +++E +S  +     + E     +  S 
Sbjct: 666 AKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSP 725

Query: 168 LKKNTAFVKKLKTITEQQRDS 188
           +K+     +K K+  +++  S
Sbjct: 726 VKEEAKTPEKAKSPVKEEAKS 746



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 52/186 (27%), Positives = 82/186 (44%), Gaps = 20/186 (10%)

Query: 2   PAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAK-KEVSKAPEDKKKRL 60
           PAE K P    EK   P  +E    E+     KE  K   K  +  K  +K+PE  K  +
Sbjct: 629 PAEVKSP----EKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPV 684

Query: 61  EDDKRKKEDKERKKKDEEKVKAEEESKKKEE---EEKKKHQEEERKKQEEQAKRQQEEEA 117
           + + +  E  +   K+E K   + +S  KEE    EK K   +E  K  E+AK   +EEA
Sbjct: 685 KAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEA 744

Query: 118 AAQMKEK--EESIQLHQEAWE-RHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAF 174
            +  K K  E++  L  ++ E +   ++E RS         P + F  +  S +K+    
Sbjct: 745 KSPEKAKSPEKAKTLDVKSPEAKTPAKEEARS---------PADKFPEKAKSPVKEEVKS 795

Query: 175 VKKLKT 180
            +K K+
Sbjct: 796 PEKAKS 801



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 48/167 (28%), Positives = 79/167 (47%), Gaps = 18/167 (10%)

Query: 6   KKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAK---KEVSKAPEDKKKRLED 62
           K+ A   EK   P  +E    E+     K +  D     AK   KE +++P DK      
Sbjct: 727 KEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFP---- 782

Query: 63  DKRKKEDKERKKKDEE-KVKAEEESKKKEEEEKKKHQ-----EEERKKQE----EQAKRQ 112
           +K K   KE  K  E+ K   +E++K  E+E  KK +     +EE K QE    E  K+ 
Sbjct: 783 EKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKA 842

Query: 113 QEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEEN 159
           +EE+A A  K +E+     +EA ++   + ++  K + A + +P+E+
Sbjct: 843 EEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVE-KPKES 888



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 32/104 (30%), Positives = 45/104 (43%), Gaps = 2/104 (1%)

Query: 994  EESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEE--EEGGAETEEQSGNESE 1051
            EE I+ V+  E+E +I      +    + +TE E  E  EEE  EE G E EE  G E E
Sbjct: 441  EEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEE 500

Query: 1052 VNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTEV 1095
               P  EE +  + +     +EE        + E E  +   EV
Sbjct: 501  TKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEV 544



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 43/145 (29%), Positives = 66/145 (45%), Gaps = 17/145 (11%)

Query: 2   PAERKKPASME----EKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAK-KEVSKAPEDK 56
           P + K P   E    EK   P  +E    E+     KE  K   K  +  KE +K PE  
Sbjct: 677 PEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKA 736

Query: 57  KKRLED-----DKRKKEDKERK---KKDEEKVKAEEESKKKEEE--EKKKHQEEERKKQE 106
           K  +++     +K K  +K +    K  E K  A+EE++   ++  EK K   +E  K  
Sbjct: 737 KSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSP 796

Query: 107 EQAKRQQEEEAAAQMKE--KEESIQ 129
           E+AK   +E+A A  KE  K+E ++
Sbjct: 797 EKAKSPLKEDAKAPEKEIPKKEEVK 821



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 47/209 (22%), Positives = 94/209 (44%), Gaps = 11/209 (5%)

Query: 16  SLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKK-RLEDDKRKKEDKERKK 74
           SLP    K  S    +  K   K  +   ++KE     E  ++ ++ ++  ++E+KE K+
Sbjct: 421 SLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKE 480

Query: 75  KD-EEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEE----AAAQMKEKEESIQ 129
           ++ +E+   EEE  +  EEE K    EE    E++AK   +EE    A A+  EKEE+ +
Sbjct: 481 EEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEA-K 539

Query: 130 LHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQRDSL 189
              E       +   + + ++ P+++  E   ++  + +K      +K K+  +++  S 
Sbjct: 540 SPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKS----PEKAKSPAKEEAKSP 595

Query: 190 SHDFNGLNLSKYIAEAVASIVEAKLKISD 218
           +   +       + E   S  EAK  + +
Sbjct: 596 AEAKSPEKAKSPVKEEAKSPAEAKSPVKE 624



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 48/208 (23%), Positives = 80/208 (38%), Gaps = 22/208 (10%)

Query: 2   PAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLE 61
           P +  K    EE  S    K  +  E ++ +  + P +  K  AK+E    PE K    E
Sbjct: 512 PEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSP-EKAKSPAKEEAKSPPEAKSPEKE 570

Query: 62  DDKRKKEDKERKK---------------KDEEKVKAEEESKKKEEEEKKKHQEEERK--- 103
           + K   E K  +K               K  EK K+  + + K   E K   +EE K   
Sbjct: 571 EAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPA 630

Query: 104 --KQEEQAKRQQEEEAAAQMKEKE-ESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENF 160
             K  E+AK   +EEA +  K K  E  +       +  ++ E +S  +     + E   
Sbjct: 631 EVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKS 690

Query: 161 FSRLDSSLKKNTAFVKKLKTITEQQRDS 188
             +  S +K+     +K K+  +++  S
Sbjct: 691 PEKAKSPVKEEAKSPEKAKSPVKEEAKS 718



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 120/577 (20%), Positives = 225/577 (38%), Gaps = 65/577 (11%)

Query: 4    ERKKPASMEEKDSLPNNKEKDCSERRTVSSKER--PKDDIKLTAKKEVSKAPEDKKKRLE 61
            E K+    EE+       E    E ++  ++E   P+ + K   K+E     E K    E
Sbjct: 477  EAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKE 536

Query: 62   DDKRKKEDKERKKKD---EEKVKAEEESKKKEEEEKKKHQE-EERKKQEEQAKRQQEEEA 117
            + K   E K  +K     +E+ K+  E+K  E+EE K   E +  +K +  AK + +  A
Sbjct: 537  EAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPA 596

Query: 118  AAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKK 177
             A+  EK +S  + +EA      +  ++ + ++  + +  E    +  S  K+     +K
Sbjct: 597  EAKSPEKAKS-PVKEEAKSPAEAKSPVKEEAKSPAEVKSPE----KAKSPTKEEAKSPEK 651

Query: 178  LKTITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKISDVNCAVHLCSLFHQRYADFA 237
             K+  +++  S     + +       E   S V+A+ K  +            +  +   
Sbjct: 652  AKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPE------------KAKSPVK 699

Query: 238  PSLLQVWKKHFEARKEEKTPNITKLRTDLRFIAELTIVGIFTDKEGLSLIYEQLKNIINA 297
                   K     ++E K+P   K ++ ++  A+       T ++  S + E+ K+   A
Sbjct: 700  EEAKSPEKAKSPVKEEAKSPE--KAKSPVKEEAK-------TPEKAKSPVKEEAKSPEKA 750

Query: 298  DRESHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKF---NLSFPPSEIISPEKQQPFQN 354
                      V S       +       + +S A+KF     S    E+ SPEK    ++
Sbjct: 751  KSPEKAKTLDVKS------PEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKA---KS 801

Query: 355  LLKEYFTSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQ 414
             LKE   +  K + +   E+++  ++  +    K  + E   K  EE A +  K    ++
Sbjct: 802  PLKEDAKAPEKEIPK-KEEVKSPVKEEEKPQEVK--VKEPPKKAEEEKAPATPK----TE 854

Query: 415  SLADLLDENMPDLPQDKPTPEE-HGPGIDIFTPGKPGEYDLEGGIWEDEDARNFYENLID 473
               D   E  P     KP  EE   P ++     KP E  +E    E ED +       +
Sbjct: 855  EKKDSKKEEAPKKEAPKPKVEEKKEPAVE-----KPKESKVEAKKEEAEDKKKVPTPEKE 909

Query: 474  LKAFVPAILFKDNEKSCQNKESNK---DDTKEAKESK-ENKEVSSPDDLELELENLEIND 529
              A V     K++ K  +  E  K   DD K  + SK   K+ ++P+  + + E  +  +
Sbjct: 910  APAKVEV---KEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPE 966

Query: 530  DTLELEGGDEAEDLT-KKLLDEQEQEDEEASTGSHLK 565
            +  + E   + +D T  K   + + E  E S+ +  K
Sbjct: 967  EKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQK 1003



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 30/123 (24%), Positives = 59/123 (47%), Gaps = 3/123 (2%)

Query: 6   KKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKR 65
           K+   +EE+       E+   E    + +E  K++     ++E ++  E++ K    ++ 
Sbjct: 452 KETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEG--GEEEEAEGGEEETKSPPAEEA 509

Query: 66  KKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQE-EERKKQEEQAKRQQEEEAAAQMKEK 124
              +KE K   +E+ K+  E+K  E+EE K   E +  +K +  AK + +    A+  EK
Sbjct: 510 ASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEK 569

Query: 125 EES 127
           EE+
Sbjct: 570 EEA 572



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 33/116 (28%), Positives = 58/116 (50%), Gaps = 13/116 (11%)

Query: 4    ERKKPASMEEK-DSLPNNK------EKDCSERRTVSSKERPKDDI--KLTAKKEVSKAPE 54
            E++ PA +E K D+ P  K      E D ++ +  S     K+    K   K+E +K PE
Sbjct: 907  EKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPE 966

Query: 55   DKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAK 110
            +K K    + + KED +   K+  K KA E+++K    ++K  +  E+  +++ AK
Sbjct: 967  EKPKT---EAKAKEDDKTLSKEPSKPKA-EKAEKSSSTDQKDSKPPEKATEDKAAK 1018



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 25/120 (20%), Positives = 57/120 (47%), Gaps = 4/120 (3%)

Query: 12  EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE 71
           EEK  +    EK+       + + +  +++    +KE  +    +++  E+++ +  ++E
Sbjct: 441 EEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEE 500

Query: 72  RKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQE----EEAAAQMKEKEES 127
            K    E+  + E+  K   +E+ K   E +  ++E+AK   E    E+A +  KE+ +S
Sbjct: 501 TKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKS 560



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 25/95 (26%), Positives = 41/95 (43%), Gaps = 7/95 (7%)

Query: 986  KIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAE---- 1041
            KIK+    E+    V++   E  +   +  +++ +    EG+  E  EEEE  G E    
Sbjct: 443  KIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETK 502

Query: 1042 ---TEEQSGNESEVNEPEEEEGSDNDDDEGEEEEE 1073
                EE +  E E   P +EE     + +  E+EE
Sbjct: 503  SPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEE 537



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 29/106 (27%), Positives = 44/106 (41%), Gaps = 14/106 (13%)

Query: 992  SLEESIRQVQDLEREFLIKLG---LVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQSGN 1048
            SL E + ++  +     +K      V +K  K+++   E  EE +  EE           
Sbjct: 421  SLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEV---------T 471

Query: 1049 ESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTE 1094
            E E  E +EEEG   +++ GEEEE E  +  T S    E      E
Sbjct: 472  EEEEKEAKEEEG--KEEEGGEEEEAEGGEEETKSPPAEEAASPEKE 515



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 22/94 (23%), Positives = 41/94 (43%), Gaps = 19/94 (20%)

Query: 2    PAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLE 61
            PAE+K+ A           ++KD  E +    +E+PK +         +KA ED K   +
Sbjct: 944  PAEKKEAAP----------EKKDTKEEKAKKPEEKPKTE---------AKAKEDDKTLSK 984

Query: 62   DDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKK 95
            +  + K +K  K    ++  ++   K  E++  K
Sbjct: 985  EPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAK 1018


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.131    0.373 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,948,750
Number of Sequences: 37866
Number of extensions: 2714153
Number of successful extensions: 107358
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1398
Number of HSP's successfully gapped in prelim test: 1130
Number of HSP's that attempted gapping in prelim test: 21661
Number of HSP's gapped (non-prelim): 35972
length of query: 1272
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1158
effective length of database: 13,930,794
effective search space: 16131859452
effective search space used: 16131859452
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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