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Search of human proteins with 183396783
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|183396783 BCL-6 interacting corepressor isoform a [Homo
sapiens]
(1721 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|183396783 BCL-6 interacting corepressor isoform a [Homo sapiens] 3495 0.0
gi|21071037 BCL-6 interacting corepressor isoform a [Homo sapiens] 3495 0.0
gi|183396787 BCL-6 interacting corepressor isoform c [Homo sapiens] 3477 0.0
gi|183396785 BCL-6 interacting corepressor isoform b [Homo sapiens] 3446 0.0
gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens] 323 7e-88
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 97 1e-19
gi|157266328 BRCA1 associated RING domain 1 [Homo sapiens] 87 1e-16
gi|239754054 PREDICTED: ankyrin repeat domain 31 [Homo sapiens] 85 7e-16
gi|239748581 PREDICTED: ankyrin repeat domain 31 [Homo sapiens] 85 7e-16
gi|239742600 PREDICTED: ankyrin repeat domain 31 [Homo sapiens] 85 7e-16
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 75 5e-13
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 75 5e-13
gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 71 8e-12
gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo sa... 70 2e-11
gi|187608777 NF-kappa-B inhibitor-like protein 2 [Homo sapiens] 69 3e-11
gi|14150169 acyl-coenzyme A binding domain containing 6 [Homo sa... 69 5e-11
gi|188219549 ankyrin repeat domain 32 [Homo sapiens] 68 9e-11
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens] 67 1e-10
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] 67 2e-10
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens] 67 2e-10
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens] 67 2e-10
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens] 67 2e-10
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens] 67 2e-10
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens] 67 2e-10
gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 67 2e-10
gi|215598574 ankyrin 1 isoform 9 [Homo sapiens] 65 6e-10
gi|70780359 ankyrin 1 isoform 1 [Homo sapiens] 65 6e-10
gi|70780357 ankyrin 1 isoform 3 [Homo sapiens] 65 6e-10
gi|70780355 ankyrin 1 isoform 2 [Homo sapiens] 65 6e-10
gi|70780353 ankyrin 1 isoform 4 [Homo sapiens] 65 6e-10
>gi|183396783 BCL-6 interacting corepressor isoform a [Homo sapiens]
Length = 1721
Score = 3495 bits (9062), Expect = 0.0
Identities = 1721/1721 (100%), Positives = 1721/1721 (100%)
Query: 1 MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDAST 60
MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDAST
Sbjct: 1 MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDAST 60
Query: 61 AHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSEKGREAATSTLGGLGFSSERNP 120
AHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSEKGREAATSTLGGLGFSSERNP
Sbjct: 61 AHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSEKGREAATSTLGGLGFSSERNP 120
Query: 121 EMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPLN 180
EMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPLN
Sbjct: 121 EMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPLN 180
Query: 181 INGASYLRLPWVNPYMEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPLYSPVCTN 240
INGASYLRLPWVNPYMEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPLYSPVCTN
Sbjct: 181 INGASYLRLPWVNPYMEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPLYSPVCTN 240
Query: 241 GERFLYLPPPHYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVD 300
GERFLYLPPPHYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVD
Sbjct: 241 GERFLYLPPPHYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVD 300
Query: 301 SHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAADTYSEFHKH 360
SHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAADTYSEFHKH
Sbjct: 301 SHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAADTYSEFHKH 360
Query: 361 YARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKD 420
YARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKD
Sbjct: 361 YARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKD 420
Query: 421 GSSPPLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSGS 480
GSSPPLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSGS
Sbjct: 421 GSSPPLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSGS 480
Query: 481 EIPKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQR 540
EIPKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQR
Sbjct: 481 EIPKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQR 540
Query: 541 SSSCPRMGGTDAVITNVSGSVSSAGRPASASPAPNANADGTKTSRSSVETTPSVIQHVGQ 600
SSSCPRMGGTDAVITNVSGSVSSAGRPASASPAPNANADGTKTSRSSVETTPSVIQHVGQ
Sbjct: 541 SSSCPRMGGTDAVITNVSGSVSSAGRPASASPAPNANADGTKTSRSSVETTPSVIQHVGQ 600
Query: 601 PPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLPY 660
PPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLPY
Sbjct: 601 PPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLPY 660
Query: 661 PAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLPYGLPTGRPEFVTYQDAL 720
PAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLPYGLPTGRPEFVTYQDAL
Sbjct: 661 PAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLPYGLPTGRPEFVTYQDAL 720
Query: 721 GLGMVHPMLIPHTPIEITKEEKPERRSRSHERARYEDPTLRNRFSEILETSSTKLHPDVP 780
GLGMVHPMLIPHTPIEITKEEKPERRSRSHERARYEDPTLRNRFSEILETSSTKLHPDVP
Sbjct: 721 GLGMVHPMLIPHTPIEITKEEKPERRSRSHERARYEDPTLRNRFSEILETSSTKLHPDVP 780
Query: 781 TDKNLKPNPNWNQGKTVVKSDKLVYVDLLREEPDAKTDTNVSKPSFAAESVGQSAEPPKP 840
TDKNLKPNPNWNQGKTVVKSDKLVYVDLLREEPDAKTDTNVSKPSFAAESVGQSAEPPKP
Sbjct: 781 TDKNLKPNPNWNQGKTVVKSDKLVYVDLLREEPDAKTDTNVSKPSFAAESVGQSAEPPKP 840
Query: 841 SVEPALQQHRDFIALREELGRISDFHETYTFKQPVFTVSKDSVLAGTNKENLGLPVSTPF 900
SVEPALQQHRDFIALREELGRISDFHETYTFKQPVFTVSKDSVLAGTNKENLGLPVSTPF
Sbjct: 841 SVEPALQQHRDFIALREELGRISDFHETYTFKQPVFTVSKDSVLAGTNKENLGLPVSTPF 900
Query: 901 LEPPLGSDGPAVTFGKTQEDPKPFCVGSAPPSVDVTPTYTKDGADEAESNDGKVLKPKPS 960
LEPPLGSDGPAVTFGKTQEDPKPFCVGSAPPSVDVTPTYTKDGADEAESNDGKVLKPKPS
Sbjct: 901 LEPPLGSDGPAVTFGKTQEDPKPFCVGSAPPSVDVTPTYTKDGADEAESNDGKVLKPKPS 960
Query: 961 KLAKRIANSAGYVGDRFKCVTTELYADSSQLSREQRALQMEGLQEDSILCLPAAYCERAM 1020
KLAKRIANSAGYVGDRFKCVTTELYADSSQLSREQRALQMEGLQEDSILCLPAAYCERAM
Sbjct: 961 KLAKRIANSAGYVGDRFKCVTTELYADSSQLSREQRALQMEGLQEDSILCLPAAYCERAM 1020
Query: 1021 MRFSELEMKEREGGHPATKDSEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNESERC 1080
MRFSELEMKEREGGHPATKDSEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNESERC
Sbjct: 1021 MRFSELEMKEREGGHPATKDSEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNESERC 1080
Query: 1081 EYSVGNKHRDPFEAPEDKDLPVEKYFVERQPVSEPPADQVASDMPHSPTLRVDRKRKVSG 1140
EYSVGNKHRDPFEAPEDKDLPVEKYFVERQPVSEPPADQVASDMPHSPTLRVDRKRKVSG
Sbjct: 1081 EYSVGNKHRDPFEAPEDKDLPVEKYFVERQPVSEPPADQVASDMPHSPTLRVDRKRKVSG 1140
Query: 1141 DSSHTETTAEEVPEDPLLKAKRRRVSKGLHPKKQRHLLHLRERWEQQVSAADGKPGRQSR 1200
DSSHTETTAEEVPEDPLLKAKRRRVSKGLHPKKQRHLLHLRERWEQQVSAADGKPGRQSR
Sbjct: 1141 DSSHTETTAEEVPEDPLLKAKRRRVSKGLHPKKQRHLLHLRERWEQQVSAADGKPGRQSR 1200
Query: 1201 KEVTQATQPEAIPQGTNITEEKPGRKRAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMK 1260
KEVTQATQPEAIPQGTNITEEKPGRKRAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMK
Sbjct: 1201 KEVTQATQPEAIPQGTNITEEKPGRKRAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMK 1260
Query: 1261 SLSSTSAGGKKQAQPSCAPASRPPAKQQKIKENQKTDVLCADEEEDCQAASLLQKYTDNS 1320
SLSSTSAGGKKQAQPSCAPASRPPAKQQKIKENQKTDVLCADEEEDCQAASLLQKYTDNS
Sbjct: 1261 SLSSTSAGGKKQAQPSCAPASRPPAKQQKIKENQKTDVLCADEEEDCQAASLLQKYTDNS 1320
Query: 1321 EKPSGKRLCKTKHLIPQESRRGLPLTGEYYVENADGKVTVRRFRKRPEPSSDYDLSPAKQ 1380
EKPSGKRLCKTKHLIPQESRRGLPLTGEYYVENADGKVTVRRFRKRPEPSSDYDLSPAKQ
Sbjct: 1321 EKPSGKRLCKTKHLIPQESRRGLPLTGEYYVENADGKVTVRRFRKRPEPSSDYDLSPAKQ 1380
Query: 1381 EPKPFDRLQQLLPASQSTQLPCSSSPQETTQSRPMPPEARRLIVNKNAGETLLQRAARLG 1440
EPKPFDRLQQLLPASQSTQLPCSSSPQETTQSRPMPPEARRLIVNKNAGETLLQRAARLG
Sbjct: 1381 EPKPFDRLQQLLPASQSTQLPCSSSPQETTQSRPMPPEARRLIVNKNAGETLLQRAARLG 1440
Query: 1441 YEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPL 1500
YEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPL
Sbjct: 1441 YEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPL 1500
Query: 1501 HDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDA 1560
HDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDA
Sbjct: 1501 HDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDA 1560
Query: 1561 SGTWDFYGSSVCEPDDESGYDVLANPPGPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQV 1620
SGTWDFYGSSVCEPDDESGYDVLANPPGPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQV
Sbjct: 1561 SGTWDFYGSSVCEPDDESGYDVLANPPGPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQV 1620
Query: 1621 SVAQGPRNWLLLSDVLKKLKMSSRIFRCNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLE 1680
SVAQGPRNWLLLSDVLKKLKMSSRIFRCNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLE
Sbjct: 1621 SVAQGPRNWLLLSDVLKKLKMSSRIFRCNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLE 1680
Query: 1681 AFNPESKELLDLVEFTNEIQTLLGSSVEWLHPSDLASDNYW 1721
AFNPESKELLDLVEFTNEIQTLLGSSVEWLHPSDLASDNYW
Sbjct: 1681 AFNPESKELLDLVEFTNEIQTLLGSSVEWLHPSDLASDNYW 1721
>gi|21071037 BCL-6 interacting corepressor isoform a [Homo sapiens]
Length = 1721
Score = 3495 bits (9062), Expect = 0.0
Identities = 1721/1721 (100%), Positives = 1721/1721 (100%)
Query: 1 MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDAST 60
MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDAST
Sbjct: 1 MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDAST 60
Query: 61 AHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSEKGREAATSTLGGLGFSSERNP 120
AHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSEKGREAATSTLGGLGFSSERNP
Sbjct: 61 AHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSEKGREAATSTLGGLGFSSERNP 120
Query: 121 EMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPLN 180
EMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPLN
Sbjct: 121 EMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPLN 180
Query: 181 INGASYLRLPWVNPYMEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPLYSPVCTN 240
INGASYLRLPWVNPYMEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPLYSPVCTN
Sbjct: 181 INGASYLRLPWVNPYMEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPLYSPVCTN 240
Query: 241 GERFLYLPPPHYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVD 300
GERFLYLPPPHYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVD
Sbjct: 241 GERFLYLPPPHYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVD 300
Query: 301 SHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAADTYSEFHKH 360
SHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAADTYSEFHKH
Sbjct: 301 SHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAADTYSEFHKH 360
Query: 361 YARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKD 420
YARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKD
Sbjct: 361 YARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKD 420
Query: 421 GSSPPLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSGS 480
GSSPPLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSGS
Sbjct: 421 GSSPPLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSGS 480
Query: 481 EIPKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQR 540
EIPKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQR
Sbjct: 481 EIPKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQR 540
Query: 541 SSSCPRMGGTDAVITNVSGSVSSAGRPASASPAPNANADGTKTSRSSVETTPSVIQHVGQ 600
SSSCPRMGGTDAVITNVSGSVSSAGRPASASPAPNANADGTKTSRSSVETTPSVIQHVGQ
Sbjct: 541 SSSCPRMGGTDAVITNVSGSVSSAGRPASASPAPNANADGTKTSRSSVETTPSVIQHVGQ 600
Query: 601 PPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLPY 660
PPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLPY
Sbjct: 601 PPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLPY 660
Query: 661 PAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLPYGLPTGRPEFVTYQDAL 720
PAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLPYGLPTGRPEFVTYQDAL
Sbjct: 661 PAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLPYGLPTGRPEFVTYQDAL 720
Query: 721 GLGMVHPMLIPHTPIEITKEEKPERRSRSHERARYEDPTLRNRFSEILETSSTKLHPDVP 780
GLGMVHPMLIPHTPIEITKEEKPERRSRSHERARYEDPTLRNRFSEILETSSTKLHPDVP
Sbjct: 721 GLGMVHPMLIPHTPIEITKEEKPERRSRSHERARYEDPTLRNRFSEILETSSTKLHPDVP 780
Query: 781 TDKNLKPNPNWNQGKTVVKSDKLVYVDLLREEPDAKTDTNVSKPSFAAESVGQSAEPPKP 840
TDKNLKPNPNWNQGKTVVKSDKLVYVDLLREEPDAKTDTNVSKPSFAAESVGQSAEPPKP
Sbjct: 781 TDKNLKPNPNWNQGKTVVKSDKLVYVDLLREEPDAKTDTNVSKPSFAAESVGQSAEPPKP 840
Query: 841 SVEPALQQHRDFIALREELGRISDFHETYTFKQPVFTVSKDSVLAGTNKENLGLPVSTPF 900
SVEPALQQHRDFIALREELGRISDFHETYTFKQPVFTVSKDSVLAGTNKENLGLPVSTPF
Sbjct: 841 SVEPALQQHRDFIALREELGRISDFHETYTFKQPVFTVSKDSVLAGTNKENLGLPVSTPF 900
Query: 901 LEPPLGSDGPAVTFGKTQEDPKPFCVGSAPPSVDVTPTYTKDGADEAESNDGKVLKPKPS 960
LEPPLGSDGPAVTFGKTQEDPKPFCVGSAPPSVDVTPTYTKDGADEAESNDGKVLKPKPS
Sbjct: 901 LEPPLGSDGPAVTFGKTQEDPKPFCVGSAPPSVDVTPTYTKDGADEAESNDGKVLKPKPS 960
Query: 961 KLAKRIANSAGYVGDRFKCVTTELYADSSQLSREQRALQMEGLQEDSILCLPAAYCERAM 1020
KLAKRIANSAGYVGDRFKCVTTELYADSSQLSREQRALQMEGLQEDSILCLPAAYCERAM
Sbjct: 961 KLAKRIANSAGYVGDRFKCVTTELYADSSQLSREQRALQMEGLQEDSILCLPAAYCERAM 1020
Query: 1021 MRFSELEMKEREGGHPATKDSEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNESERC 1080
MRFSELEMKEREGGHPATKDSEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNESERC
Sbjct: 1021 MRFSELEMKEREGGHPATKDSEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNESERC 1080
Query: 1081 EYSVGNKHRDPFEAPEDKDLPVEKYFVERQPVSEPPADQVASDMPHSPTLRVDRKRKVSG 1140
EYSVGNKHRDPFEAPEDKDLPVEKYFVERQPVSEPPADQVASDMPHSPTLRVDRKRKVSG
Sbjct: 1081 EYSVGNKHRDPFEAPEDKDLPVEKYFVERQPVSEPPADQVASDMPHSPTLRVDRKRKVSG 1140
Query: 1141 DSSHTETTAEEVPEDPLLKAKRRRVSKGLHPKKQRHLLHLRERWEQQVSAADGKPGRQSR 1200
DSSHTETTAEEVPEDPLLKAKRRRVSKGLHPKKQRHLLHLRERWEQQVSAADGKPGRQSR
Sbjct: 1141 DSSHTETTAEEVPEDPLLKAKRRRVSKGLHPKKQRHLLHLRERWEQQVSAADGKPGRQSR 1200
Query: 1201 KEVTQATQPEAIPQGTNITEEKPGRKRAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMK 1260
KEVTQATQPEAIPQGTNITEEKPGRKRAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMK
Sbjct: 1201 KEVTQATQPEAIPQGTNITEEKPGRKRAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMK 1260
Query: 1261 SLSSTSAGGKKQAQPSCAPASRPPAKQQKIKENQKTDVLCADEEEDCQAASLLQKYTDNS 1320
SLSSTSAGGKKQAQPSCAPASRPPAKQQKIKENQKTDVLCADEEEDCQAASLLQKYTDNS
Sbjct: 1261 SLSSTSAGGKKQAQPSCAPASRPPAKQQKIKENQKTDVLCADEEEDCQAASLLQKYTDNS 1320
Query: 1321 EKPSGKRLCKTKHLIPQESRRGLPLTGEYYVENADGKVTVRRFRKRPEPSSDYDLSPAKQ 1380
EKPSGKRLCKTKHLIPQESRRGLPLTGEYYVENADGKVTVRRFRKRPEPSSDYDLSPAKQ
Sbjct: 1321 EKPSGKRLCKTKHLIPQESRRGLPLTGEYYVENADGKVTVRRFRKRPEPSSDYDLSPAKQ 1380
Query: 1381 EPKPFDRLQQLLPASQSTQLPCSSSPQETTQSRPMPPEARRLIVNKNAGETLLQRAARLG 1440
EPKPFDRLQQLLPASQSTQLPCSSSPQETTQSRPMPPEARRLIVNKNAGETLLQRAARLG
Sbjct: 1381 EPKPFDRLQQLLPASQSTQLPCSSSPQETTQSRPMPPEARRLIVNKNAGETLLQRAARLG 1440
Query: 1441 YEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPL 1500
YEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPL
Sbjct: 1441 YEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPL 1500
Query: 1501 HDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDA 1560
HDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDA
Sbjct: 1501 HDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDA 1560
Query: 1561 SGTWDFYGSSVCEPDDESGYDVLANPPGPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQV 1620
SGTWDFYGSSVCEPDDESGYDVLANPPGPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQV
Sbjct: 1561 SGTWDFYGSSVCEPDDESGYDVLANPPGPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQV 1620
Query: 1621 SVAQGPRNWLLLSDVLKKLKMSSRIFRCNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLE 1680
SVAQGPRNWLLLSDVLKKLKMSSRIFRCNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLE
Sbjct: 1621 SVAQGPRNWLLLSDVLKKLKMSSRIFRCNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLE 1680
Query: 1681 AFNPESKELLDLVEFTNEIQTLLGSSVEWLHPSDLASDNYW 1721
AFNPESKELLDLVEFTNEIQTLLGSSVEWLHPSDLASDNYW
Sbjct: 1681 AFNPESKELLDLVEFTNEIQTLLGSSVEWLHPSDLASDNYW 1721
>gi|183396787 BCL-6 interacting corepressor isoform c [Homo sapiens]
Length = 1755
Score = 3477 bits (9017), Expect = 0.0
Identities = 1721/1755 (98%), Positives = 1721/1755 (98%), Gaps = 34/1755 (1%)
Query: 1 MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDAST 60
MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDAST
Sbjct: 1 MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDAST 60
Query: 61 AHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSEKGREAATSTLGGLGFSSERNP 120
AHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSEKGREAATSTLGGLGFSSERNP
Sbjct: 61 AHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSEKGREAATSTLGGLGFSSERNP 120
Query: 121 EMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPLN 180
EMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPLN
Sbjct: 121 EMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPLN 180
Query: 181 INGASYLRLPWVNPYMEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPLYSPVCTN 240
INGASYLRLPWVNPYMEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPLYSPVCTN
Sbjct: 181 INGASYLRLPWVNPYMEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPLYSPVCTN 240
Query: 241 GERFLYLPPPHYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVD 300
GERFLYLPPPHYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVD
Sbjct: 241 GERFLYLPPPHYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVD 300
Query: 301 SHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAADTYSEFHKH 360
SHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAADTYSEFHKH
Sbjct: 301 SHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAADTYSEFHKH 360
Query: 361 YARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKD 420
YARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKD
Sbjct: 361 YARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKD 420
Query: 421 GSSPPLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSGS 480
GSSPPLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSGS
Sbjct: 421 GSSPPLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSGS 480
Query: 481 EIPKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQR 540
EIPKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQR
Sbjct: 481 EIPKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQR 540
Query: 541 SSSCPRMGGTDAVITNVSGSVSSAGRPASASPAPNANADGTKTSRSSVETTPSVIQHVGQ 600
SSSCPRMGGTDAVITNVSGSVSSAGRPASASPAPNANADGTKTSRSSVETTPSVIQHVGQ
Sbjct: 541 SSSCPRMGGTDAVITNVSGSVSSAGRPASASPAPNANADGTKTSRSSVETTPSVIQHVGQ 600
Query: 601 PPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLPY 660
PPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLPY
Sbjct: 601 PPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLPY 660
Query: 661 PAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLPYGLPTGRPEFVTYQDAL 720
PAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLPYGLPTGRPEFVTYQDAL
Sbjct: 661 PAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLPYGLPTGRPEFVTYQDAL 720
Query: 721 GLGMVHPMLIPHTPIEITKEEKPERRSRSHERARYEDPTLRNRFSEILETSSTKLHPDVP 780
GLGMVHPMLIPHTPIEITKEEKPERRSRSHERARYEDPTLRNRFSEILETSSTKLHPDVP
Sbjct: 721 GLGMVHPMLIPHTPIEITKEEKPERRSRSHERARYEDPTLRNRFSEILETSSTKLHPDVP 780
Query: 781 TDKNLKPNPNWNQGKTVVKSDKLVYVDLLREEPDAKTDTNVSKPSFAAESVGQSAEPPKP 840
TDKNLKPNPNWNQGKTVVKSDKLVYVDLLREEPDAKTDTNVSKPSFAAESVGQSAEPPKP
Sbjct: 781 TDKNLKPNPNWNQGKTVVKSDKLVYVDLLREEPDAKTDTNVSKPSFAAESVGQSAEPPKP 840
Query: 841 SVEPALQQHRDFIALREELGRISDFHETYTFKQPVFTVSKDSVLAGTNKENLGLPVSTPF 900
SVEPALQQHRDFIALREELGRISDFHETYTFKQPVFTVSKDSVLAGTNKENLGLPVSTPF
Sbjct: 841 SVEPALQQHRDFIALREELGRISDFHETYTFKQPVFTVSKDSVLAGTNKENLGLPVSTPF 900
Query: 901 LEPPLGSDGPAVTFGKTQEDPKPFCVGSAPPSVDVTPTYTKDGADEAESNDGKVLKPKPS 960
LEPPLGSDGPAVTFGKTQEDPKPFCVGSAPPSVDVTPTYTKDGADEAESNDGKVLKPKPS
Sbjct: 901 LEPPLGSDGPAVTFGKTQEDPKPFCVGSAPPSVDVTPTYTKDGADEAESNDGKVLKPKPS 960
Query: 961 KLAKRIANSAGYVGDRFKCVTTELYADSSQLSREQRALQMEGLQEDSILCLPAAYCERAM 1020
KLAKRIANSAGYVGDRFKCVTTELYADSSQLSREQRALQMEGLQEDSILCLPAAYCERAM
Sbjct: 961 KLAKRIANSAGYVGDRFKCVTTELYADSSQLSREQRALQMEGLQEDSILCLPAAYCERAM 1020
Query: 1021 MRFSELEMKEREGGHPATKDSEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNESERC 1080
MRFSELEMKEREGGHPATKDSEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNESERC
Sbjct: 1021 MRFSELEMKEREGGHPATKDSEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNESERC 1080
Query: 1081 EYSVGNKHRDPFEAPEDKDLPVEKYFVERQPVSEPPADQVASDMPHSPTLRVDRKRKVSG 1140
EYSVGNKHRDPFEAPEDKDLPVEKYFVERQPVSEPPADQVASDMPHSPTLRVDRKRKVSG
Sbjct: 1081 EYSVGNKHRDPFEAPEDKDLPVEKYFVERQPVSEPPADQVASDMPHSPTLRVDRKRKVSG 1140
Query: 1141 DSSHTETTAEEVPEDPLLKAKRRRVSK--------------------------------- 1167
DSSHTETTAEEVPEDPLLKAKRRRVSK
Sbjct: 1141 DSSHTETTAEEVPEDPLLKAKRRRVSKDDWPEREMTNSSSNHLEDPHYSELTNLKVCIEL 1200
Query: 1168 -GLHPKKQRHLLHLRERWEQQVSAADGKPGRQSRKEVTQATQPEAIPQGTNITEEKPGRK 1226
GLHPKKQRHLLHLRERWEQQVSAADGKPGRQSRKEVTQATQPEAIPQGTNITEEKPGRK
Sbjct: 1201 TGLHPKKQRHLLHLRERWEQQVSAADGKPGRQSRKEVTQATQPEAIPQGTNITEEKPGRK 1260
Query: 1227 RAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMKSLSSTSAGGKKQAQPSCAPASRPPAK 1286
RAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMKSLSSTSAGGKKQAQPSCAPASRPPAK
Sbjct: 1261 RAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMKSLSSTSAGGKKQAQPSCAPASRPPAK 1320
Query: 1287 QQKIKENQKTDVLCADEEEDCQAASLLQKYTDNSEKPSGKRLCKTKHLIPQESRRGLPLT 1346
QQKIKENQKTDVLCADEEEDCQAASLLQKYTDNSEKPSGKRLCKTKHLIPQESRRGLPLT
Sbjct: 1321 QQKIKENQKTDVLCADEEEDCQAASLLQKYTDNSEKPSGKRLCKTKHLIPQESRRGLPLT 1380
Query: 1347 GEYYVENADGKVTVRRFRKRPEPSSDYDLSPAKQEPKPFDRLQQLLPASQSTQLPCSSSP 1406
GEYYVENADGKVTVRRFRKRPEPSSDYDLSPAKQEPKPFDRLQQLLPASQSTQLPCSSSP
Sbjct: 1381 GEYYVENADGKVTVRRFRKRPEPSSDYDLSPAKQEPKPFDRLQQLLPASQSTQLPCSSSP 1440
Query: 1407 QETTQSRPMPPEARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCA 1466
QETTQSRPMPPEARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCA
Sbjct: 1441 QETTQSRPMPPEARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCA 1500
Query: 1467 LHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLAT 1526
LHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLAT
Sbjct: 1501 LHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLAT 1560
Query: 1527 YSGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDASGTWDFYGSSVCEPDDESGYDVLANP 1586
YSGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDASGTWDFYGSSVCEPDDESGYDVLANP
Sbjct: 1561 YSGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDASGTWDFYGSSVCEPDDESGYDVLANP 1620
Query: 1587 PGPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQVSVAQGPRNWLLLSDVLKKLKMSSRIF 1646
PGPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQVSVAQGPRNWLLLSDVLKKLKMSSRIF
Sbjct: 1621 PGPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQVSVAQGPRNWLLLSDVLKKLKMSSRIF 1680
Query: 1647 RCNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLEAFNPESKELLDLVEFTNEIQTLLGSS 1706
RCNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLEAFNPESKELLDLVEFTNEIQTLLGSS
Sbjct: 1681 RCNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLEAFNPESKELLDLVEFTNEIQTLLGSS 1740
Query: 1707 VEWLHPSDLASDNYW 1721
VEWLHPSDLASDNYW
Sbjct: 1741 VEWLHPSDLASDNYW 1755
>gi|183396785 BCL-6 interacting corepressor isoform b [Homo sapiens]
Length = 1703
Score = 3446 bits (8936), Expect = 0.0
Identities = 1703/1721 (98%), Positives = 1703/1721 (98%), Gaps = 18/1721 (1%)
Query: 1 MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDAST 60
MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDAST
Sbjct: 1 MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDAST 60
Query: 61 AHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSEKGREAATSTLGGLGFSSERNP 120
AHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSEKGREAATSTLGGLGFSSERNP
Sbjct: 61 AHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSEKGREAATSTLGGLGFSSERNP 120
Query: 121 EMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPLN 180
EMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPLN
Sbjct: 121 EMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPLN 180
Query: 181 INGASYLRLPWVNPYMEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPLYSPVCTN 240
INGASYLRLPWVNPYMEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPLYSPVCTN
Sbjct: 181 INGASYLRLPWVNPYMEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPLYSPVCTN 240
Query: 241 GERFLYLPPPHYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVD 300
GERFLYLPPPHYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVD
Sbjct: 241 GERFLYLPPPHYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVD 300
Query: 301 SHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAADTYSEFHKH 360
SHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAADTYSEFHKH
Sbjct: 301 SHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAADTYSEFHKH 360
Query: 361 YARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKD 420
YARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKD
Sbjct: 361 YARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKD 420
Query: 421 GSSPPLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSGS 480
GSSPPLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSGS
Sbjct: 421 GSSPPLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSGS 480
Query: 481 EIPKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQR 540
EIPKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQR
Sbjct: 481 EIPKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQR 540
Query: 541 SSSCPRMGGTDAVITNVSGSVSSAGRPASASPAPNANADGTKTSRSSVETTPSVIQHVGQ 600
SSSCPRMGGTDAVITNVSGSVSSAGRPASASPAPNANADGTKTSRSSVETTPSVIQHVGQ
Sbjct: 541 SSSCPRMGGTDAVITNVSGSVSSAGRPASASPAPNANADGTKTSRSSVETTPSVIQHVGQ 600
Query: 601 PPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLPY 660
PPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLPY
Sbjct: 601 PPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLPY 660
Query: 661 PAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLPYGLPTGRPEFVTYQDAL 720
PAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLPYGLPTGRPEFVTYQDAL
Sbjct: 661 PAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLPYGLPTGRPEFVTYQDAL 720
Query: 721 GLGMVHPMLIPHTPIEITKEEKPERRSRSHERARYEDPTLRNRFSEILETSSTKLHPDVP 780
GLGMVHPMLIPHTPIEITKEEKPERRSRSHERARYEDPTLRNRFSEILETSSTKLHPDVP
Sbjct: 721 GLGMVHPMLIPHTPIEITKEEKPERRSRSHERARYEDPTLRNRFSEILETSSTKLHPDVP 780
Query: 781 TDKNLKPNPNWNQGKTVVKSDKLVYVDLLREEPDAKTDTNVSKPSFAAESVGQSAEPPKP 840
TDKNLKPNPNWNQGKTVVKSDKLVYVDLLREEPDAKTDTNVSKPSFAAESVGQSAEPPKP
Sbjct: 781 TDKNLKPNPNWNQGKTVVKSDKLVYVDLLREEPDAKTDTNVSKPSFAAESVGQSAEPPKP 840
Query: 841 SVEPALQQHRDFIALREELGRISDFHETYTFKQPVFTVSKDSVLAGTNKENLGLPVSTPF 900
SVEPALQQHRDFIALREELGRISDFHETYTFKQPVFTVSKDSVLAGTNKENLGLPVSTPF
Sbjct: 841 SVEPALQQHRDFIALREELGRISDFHETYTFKQPVFTVSKDSVLAGTNKENLGLPVSTPF 900
Query: 901 LEPPLGSDGPAVTFGKTQEDPKPFCVGSAPPSVDVTPTYTKDGADEAESNDGKVLKPKPS 960
LEPPLGSDGPAVTFGKTQEDPKPFCVGSAPPSVDVTPTYTKDGADEAESNDGKVLKPKPS
Sbjct: 901 LEPPLGSDGPAVTFGKTQEDPKPFCVGSAPPSVDVTPTYTKDGADEAESNDGKVLKPKPS 960
Query: 961 KLAKRIANSAGYVGDRFKCVTTELYADSSQLSREQRALQMEGLQEDSILCLPAAYCERAM 1020
KLAKRIANSAGYVGDRFKCVTTELYADSSQLSREQRALQ RAM
Sbjct: 961 KLAKRIANSAGYVGDRFKCVTTELYADSSQLSREQRALQ------------------RAM 1002
Query: 1021 MRFSELEMKEREGGHPATKDSEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNESERC 1080
MRFSELEMKEREGGHPATKDSEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNESERC
Sbjct: 1003 MRFSELEMKEREGGHPATKDSEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNESERC 1062
Query: 1081 EYSVGNKHRDPFEAPEDKDLPVEKYFVERQPVSEPPADQVASDMPHSPTLRVDRKRKVSG 1140
EYSVGNKHRDPFEAPEDKDLPVEKYFVERQPVSEPPADQVASDMPHSPTLRVDRKRKVSG
Sbjct: 1063 EYSVGNKHRDPFEAPEDKDLPVEKYFVERQPVSEPPADQVASDMPHSPTLRVDRKRKVSG 1122
Query: 1141 DSSHTETTAEEVPEDPLLKAKRRRVSKGLHPKKQRHLLHLRERWEQQVSAADGKPGRQSR 1200
DSSHTETTAEEVPEDPLLKAKRRRVSKGLHPKKQRHLLHLRERWEQQVSAADGKPGRQSR
Sbjct: 1123 DSSHTETTAEEVPEDPLLKAKRRRVSKGLHPKKQRHLLHLRERWEQQVSAADGKPGRQSR 1182
Query: 1201 KEVTQATQPEAIPQGTNITEEKPGRKRAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMK 1260
KEVTQATQPEAIPQGTNITEEKPGRKRAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMK
Sbjct: 1183 KEVTQATQPEAIPQGTNITEEKPGRKRAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMK 1242
Query: 1261 SLSSTSAGGKKQAQPSCAPASRPPAKQQKIKENQKTDVLCADEEEDCQAASLLQKYTDNS 1320
SLSSTSAGGKKQAQPSCAPASRPPAKQQKIKENQKTDVLCADEEEDCQAASLLQKYTDNS
Sbjct: 1243 SLSSTSAGGKKQAQPSCAPASRPPAKQQKIKENQKTDVLCADEEEDCQAASLLQKYTDNS 1302
Query: 1321 EKPSGKRLCKTKHLIPQESRRGLPLTGEYYVENADGKVTVRRFRKRPEPSSDYDLSPAKQ 1380
EKPSGKRLCKTKHLIPQESRRGLPLTGEYYVENADGKVTVRRFRKRPEPSSDYDLSPAKQ
Sbjct: 1303 EKPSGKRLCKTKHLIPQESRRGLPLTGEYYVENADGKVTVRRFRKRPEPSSDYDLSPAKQ 1362
Query: 1381 EPKPFDRLQQLLPASQSTQLPCSSSPQETTQSRPMPPEARRLIVNKNAGETLLQRAARLG 1440
EPKPFDRLQQLLPASQSTQLPCSSSPQETTQSRPMPPEARRLIVNKNAGETLLQRAARLG
Sbjct: 1363 EPKPFDRLQQLLPASQSTQLPCSSSPQETTQSRPMPPEARRLIVNKNAGETLLQRAARLG 1422
Query: 1441 YEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPL 1500
YEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPL
Sbjct: 1423 YEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPL 1482
Query: 1501 HDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDA 1560
HDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDA
Sbjct: 1483 HDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDA 1542
Query: 1561 SGTWDFYGSSVCEPDDESGYDVLANPPGPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQV 1620
SGTWDFYGSSVCEPDDESGYDVLANPPGPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQV
Sbjct: 1543 SGTWDFYGSSVCEPDDESGYDVLANPPGPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQV 1602
Query: 1621 SVAQGPRNWLLLSDVLKKLKMSSRIFRCNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLE 1680
SVAQGPRNWLLLSDVLKKLKMSSRIFRCNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLE
Sbjct: 1603 SVAQGPRNWLLLSDVLKKLKMSSRIFRCNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLE 1662
Query: 1681 AFNPESKELLDLVEFTNEIQTLLGSSVEWLHPSDLASDNYW 1721
AFNPESKELLDLVEFTNEIQTLLGSSVEWLHPSDLASDNYW
Sbjct: 1663 AFNPESKELLDLVEFTNEIQTLLGSSVEWLHPSDLASDNYW 1703
>gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]
Length = 1711
Score = 323 bits (829), Expect = 7e-88
Identities = 209/546 (38%), Positives = 298/546 (54%), Gaps = 46/546 (8%)
Query: 1196 GRQSRKEVTQATQPEAIPQGTNITEEKPGRKRAEAKGN-RSWSEESLKPSDNEQGLPVFS 1254
G + + + + T+PE+ G + G +AK + R + L Q + S
Sbjct: 1175 GVRGKHKHRKPTKPESQSPGKRADSHEEGSLEKKAKSSFRDFIPVVLSTRTRSQSGSICS 1234
Query: 1255 GSPPMKSLSSTSAGGKKQAQPSCAP--ASRPPAKQQKIKENQKTDVLCADEEED------ 1306
M + S G ++ P+ + PAK++K+++ Q+ + +D
Sbjct: 1235 SFAGM----ADSDMGSQEVFPTEEEEEVTPTPAKRRKVRKTQRDTQYRSHHAQDKSLLSQ 1290
Query: 1307 --------------CQAASLLQKYTDNSEKPSGKRLCKTKHLIPQESRRGLPLTGEYYVE 1352
+AA + + E+ + L K K Q+SR+ TGEY E
Sbjct: 1291 GRRHLWRAREMPWRTEAARQMWDTNEEEEEEEEEGLLKRKKRRRQKSRKYQ--TGEYLTE 1348
Query: 1353 NAD-----GKVTVRRFRKRPEPSSDYDLSPAKQEPKPFDRLQQLLPASQSTQLPCSSSPQ 1407
D G+ ++ RK+ SS + Q + S + LP +
Sbjct: 1349 QEDEQRRKGRADLKA-RKQKTSSSQSLEHRLRNRNLLLPNKVQGISDSPNGFLPNNLEEP 1407
Query: 1408 ETTQSRPMPPEARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCAL 1467
++ P R+ A T+ + A ++VVLYCL+ DVNHRDNAGY AL
Sbjct: 1408 ACLENSEKPSGKRKCKTKHMA--TVSEEA-----KDVVLYCLQKDSEDVNHRDNAGYTAL 1460
Query: 1468 HEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATY 1527
HEAC+RGW +I+ LLE+GA+VNCSAQDGTRP+HDAV ND+LE + LLLSYGADPTLATY
Sbjct: 1461 HEACSRGWTDILNILLEHGANVNCSAQDGTRPVHDAVVNDNLETIWLLLSYGADPTLATY 1520
Query: 1528 SGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDASGTWDFYGSSVCEPDDESGYDVLANPP 1587
SG+T MK+ S+ M++FL+D+L+DLQGR + D +WDFY SSV E D D+L NPP
Sbjct: 1521 SGQTAMKLASSDTMKRFLSDHLSDLQGRAEGDPGVSWDFYSSSVLEEKDGFACDLLHNPP 1580
Query: 1588 GPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQVSVAQGPRNWLLLSDVLKKLKMSSRIFR 1647
G DQ+ DD D F FE S+ PLLPCYN+QVSV++GP NW L SDVLK+LK+SSRIF+
Sbjct: 1581 GSSDQEGDDPMEEDDFMFELSDKPLLPCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQ 1640
Query: 1648 CNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLEAFN----PESKELLDLVEFTNEIQTLL 1703
FP+ EI T+ +AEFYRQV++S L + ++ + P S E ++LV + ++ LL
Sbjct: 1641 ARFPHFEITTMPKAEFYRQVASSQLLTPAERPGGLDDRSPPGSSETVELVRYEPDLLRLL 1700
Query: 1704 GSSVEW 1709
GS VE+
Sbjct: 1701 GSEVEF 1706
Score = 52.0 bits (123), Expect = 5e-06
Identities = 149/707 (21%), Positives = 244/707 (34%), Gaps = 130/707 (18%)
Query: 1 MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDAST 60
M+S PLY VH+W +S+R+RMCG +E+R+ ++D +++ D
Sbjct: 1 MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTG---------------DCQH 45
Query: 61 AHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSE-KGREAATSTLGGLGFSSERN 119
+ + S + L + G GS +G + S LG SE
Sbjct: 46 FGSQEFCVSSSFSKVEL--------------TAVGSGSNARGADPDGSATEKLGHKSED- 90
Query: 120 PEMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPL 179
KP+ P+ A + GF +P GL PASD
Sbjct: 91 -----KPDDPQPKMDYAGNVAEAEGFLVPLSSPGD------------GLKLPASDSAEAS 133
Query: 180 NING-ASYLRLPWVNPYMEGATPAIYPFLDS------PNKYSLNMYKALLPQQS-----Y 227
N S+ L +PA LDS N + L +P +
Sbjct: 134 NSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLGTGVPVEGTLPLVT 193
Query: 228 SLAQPLYSPVCTNGERFLYLP--------PPHYVGPHIPSSLASPMRLST--PSASPAIP 277
+ PL +P+C +P P V +P S P++++T P+ SP +
Sbjct: 194 TNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLA 253
Query: 278 PLVHCADKSLPWKMGVSPGNPVDSHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSP 337
P+ A +S NP+ A + P + V P L +P S
Sbjct: 254 PVPALAPAPPSVPTLISDSNPLSVSA--SVLVPVPASAPPSGPVPLSAPAPAPLSVPVSA 311
Query: 338 RPSPRVHLPTQPAADTYSEFHKHYARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAP 397
P + P P+A T ++ P+ S P S+G P P
Sbjct: 312 PPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGP-PSTP 370
Query: 398 EGGEGAQPVPGHARKTAVQDRKDGSSPPLLEKQTVTKDVTDKPLDLSSKV--VDVDASKA 455
P P A A +P + T T P+ S + V A++A
Sbjct: 371 TLIPAFAPTPVPAPTPAPIFT---PAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQA 427
Query: 456 DHMKKM-----APTVLVHSR-------AGSGLVLSGSEIP-----KETLSPP------GN 492
M+K+ TVL S+ G LS + +P TL+ P +
Sbjct: 428 PAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQD 487
Query: 493 GC--AIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQRSSSCPRMGGT 550
C + S + + P ++ V P ++ K +SL+ L P +++ P G
Sbjct: 488 RCLPGVLASPELRSYPYAFSVARPLTSD---SKLVSLEVNRLPCTSPSGSTTTQPAPDGV 544
Query: 551 DAVITNVSGSVSSA---GRPASASPAPNANA----------------DGTKTSRSSVETT 591
+ + S +SA P PAP+ ++ +GT + S +++
Sbjct: 545 PGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSP 604
Query: 592 PSVIQHVGQPPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSI 638
P + + + PP ++ SSK + P P N+ PP +
Sbjct: 605 PQLEREMASPPEC-SEMPLDLSSKSNRQKLPLP----NQRKTPPMPV 646
Score = 47.8 bits (112), Expect = 9e-05
Identities = 126/565 (22%), Positives = 191/565 (33%), Gaps = 103/565 (18%)
Query: 196 MEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPL---YSP--VCTNGERFLYLPPP 250
M ATPA P +P S ++ + P Q + + P V T + +Y+PPP
Sbjct: 397 MPAATPAAIP-TSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPP 455
Query: 251 HYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVDSHAYPHIQNS 310
P ++L + + +S+ P +P + D+ LP + SP + +YP+ +
Sbjct: 456 SCGQPLSVATLPTTLGVSSTLTLPVLPS--YLQDRCLPGVL-ASP----ELRSYPYAFSV 508
Query: 311 KQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAAD------TYSEFHKHYARI 364
+P +K V +L + P SP TQPA D + A++
Sbjct: 509 ARPLTSDSKLV--------SLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKV 560
Query: 365 STSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKDGSSP 424
+P L P + + PA K P E V K+ Q ++ +SP
Sbjct: 561 LPTPQPLLPAPSGSSAPPHPA------KMPSGTEQQTEGTSVTFSPLKSPPQLEREMASP 614
Query: 425 PLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSG--SEI 482
P + ++ PLDLSSK + K VL S +LS S
Sbjct: 615 P---------ECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLSTVLSRS 665
Query: 483 PKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNG-KSMSLKNKALDWAIPQQRS 541
+ T + GN + + + S +V+ P NG S +KN
Sbjct: 666 QRTTQAAGGN-----VTSCLGSTSSPFVI---FPEIVRNGDPSTWVKN------------ 705
Query: 542 SSCPRMGGTDAVITNVSGSVSSAGRPASASPAPN--ANADGTKTSRSSVETTPSVIQHVG 599
+ A+I+ + G+ P AS N N + R + P I G
Sbjct: 706 --------STALISTIPGTYVGVANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQG 757
Query: 600 QPPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLP 659
+P T A S GA+ P + + P E P P + P
Sbjct: 758 EPKGTGATCGKKGSQAGAE-GQPSTVKRYTPARIAPGLPGCQTKELSLWKPTG-PANIYP 815
Query: 660 YPAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLP---------------- 703
+ G S L Y LL G G L P G P
Sbjct: 816 RCSVNGKPTSTQVLPVGWSPYHQASLLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSL 875
Query: 704 ------YGLPTGRP----EFVTYQD 718
+GLP G+P FV QD
Sbjct: 876 SSSEAVHGLPEGQPRPGGSFVPEQD 900
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 97.1 bits (240), Expect = 1e-19
Identities = 84/278 (30%), Positives = 122/278 (43%), Gaps = 41/278 (14%)
Query: 1303 EEEDCQAASLLQKYTDNSEK--------PSGKRLCKTKHLIPQESRRGLPLTGEYYVENA 1354
+EE ++ +++K T +K P +R K + + S+R LP T E
Sbjct: 12 QEELPLSSDMVEKQTGKKDKDKVSLTKTPKLERGDGGKEVRERASKRKLPFTAGANGEQK 71
Query: 1355 DG---KVTVRRFRKRPEP----------------SSDYDLSPAKQEPKPFDRLQQLLPAS 1395
D K R R + EP + Y LS +Q L + A
Sbjct: 72 DSDTEKQGPERKRIKKEPVTRKAGLLFGMGLSGIRAGYPLSERQQVA-----LLMQMTAE 126
Query: 1396 QSTQLPCSSSPQETTQSR------PMPPEARRLIVNKN--AGETLLQRAARLGYEEVVLY 1447
+S P ++P+ +QS P + VNK GET L RAA G +
Sbjct: 127 ESANSPVDTTPKHPSQSTVCQKGTPNSASKTKDKVNKRNERGETRLHRAAIRGDARRIKE 186
Query: 1448 CLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVEND 1507
+ DVN +D AG+ ALHEAC RG+ ++ + LL GA+VN D PLHDA N
Sbjct: 187 LISEG-ADVNVKDFAGWTALHEACNRGYYDVAKQLLAAGAEVNTKGLDDDTPLHDAANNG 245
Query: 1508 HLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFL 1545
H ++V+LLL YG +P + G T +K+ +S M L
Sbjct: 246 HYKVVKLLLRYGGNPQQSNRKGETPLKVANSPTMVNLL 283
>gi|157266328 BRCA1 associated RING domain 1 [Homo sapiens]
Length = 777
Score = 87.0 bits (214), Expect = 1e-16
Identities = 106/416 (25%), Positives = 160/416 (38%), Gaps = 47/416 (11%)
Query: 1135 KRKVSGDSSHTETTAEEVPEDPLLKAKRRRVSKGLHPKKQRHLLHLRERWEQQVSAADGK 1194
K+ S E + P D +AK+ G KK+ L + ++W + DG+
Sbjct: 170 KKDASAQQDSYEFVSPSPPADVSERAKKASARSGKKQKKKT-LAEINQKWNLEAEKEDGE 228
Query: 1195 ---PGRQSRKEVTQATQPEAI--PQGTNITEEKPGRKRAEAKGNRSWSEESLKPSDNEQG 1249
+K V+ +QP I PQ + E++ S +E SL ++ +
Sbjct: 229 FDSKEESKQKLVSFCSQPSVISSPQINGEIDLLASGSLTESECFGSLTEVSLPLAEQIE- 287
Query: 1250 LPVFSGSPPMKSLSSTSAGGKKQAQPSCAPASRPPAKQQKIKENQKTDVLCADEEEDCQA 1309
SP KS + K + S P K + + L + + C+
Sbjct: 288 ------SPDTKSRNEVVTPEKVCKNYLTSKKSLPLENNGKRGHHNR---LSSPISKRCRT 338
Query: 1310 ASLLQKYTDNSEKPSGKRLCKTKHLIPQESRRGLPLTGEYYVENADGKVTVRRFRKRPEP 1369
+ L SG + K +P E+ +PL + KV RK
Sbjct: 339 SIL---------STSGDFV---KQTVPSEN---IPLPECSSPPSCKRKVGGTSGRKNSNM 383
Query: 1370 SSDYDLSPAKQEPKPFDRLQQLLPASQSTQLPCSSSPQETTQSRPMPPEARRLIVNKNAG 1429
S D L P + + L SS + + M + + G
Sbjct: 384 S---------------DEFISLSPGTPPSTLSSSSYRRVMSSPSAMKLLPNMAVKRNHRG 428
Query: 1430 ETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADV 1489
ETLL A+ G V Y L+N D N +D+AG+ LHEAC G L +V LL++ A V
Sbjct: 429 ETLLHIASIKGDIPSVEYLLQNG-SDPNVKDHAGWTPLHEACNHGHLKVVELLLQHKALV 487
Query: 1490 NCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFL 1545
N + PLHDA +N H++IV+LLLSYGA G + T E M+ L
Sbjct: 488 NTTGYQNDSPLHDAAKNGHVDIVKLLLSYGASRNAVNIFGLRPVDYTDDESMKSLL 543
>gi|239754054 PREDICTED: ankyrin repeat domain 31 [Homo sapiens]
Length = 1873
Score = 84.7 bits (208), Expect = 7e-16
Identities = 53/144 (36%), Positives = 76/144 (52%), Gaps = 2/144 (1%)
Query: 1418 EARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLN 1477
+A R+ GE+ L A R G +V +E+ DVN DNAG+ LHEA G ++
Sbjct: 1144 KAGRINKRNARGESQLHLAVRRGNLPLVKALIESG-ADVNLNDNAGWTPLHEASNEGSID 1202
Query: 1478 IVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTH 1537
I+ LL+ GA VNC DG PLHDAV N+HL+ +LL GA+P ++ +
Sbjct: 1203 IIVELLKAGAKVNCENIDGILPLHDAVANNHLKAAEILLQNGANPNQKDQKQKSALDEAD 1262
Query: 1538 SELMEKFLTDY-LNDLQGRNDDDA 1560
E M++ L Y + R++ DA
Sbjct: 1263 DEKMKELLRSYGAIETVNRDESDA 1286
Score = 72.4 bits (176), Expect = 4e-12
Identities = 44/121 (36%), Positives = 62/121 (51%), Gaps = 1/121 (0%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
GE L+ +AA ++V +C++ K +VN AG+ ALHEA G+ LL+ GAD
Sbjct: 489 GENLVYKAALHDDADLVHHCIK-KGGNVNQPSYAGWTALHEASVGGFYRTASELLKGGAD 547
Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDY 1548
VN PLHDAV N H ++ LLL GADP G+ + M++ L Y
Sbjct: 548 VNIKGLYQITPLHDAVMNGHYKVAELLLLNGADPLFRNDDGKCALDEAKDLCMKRLLERY 607
Query: 1549 L 1549
+
Sbjct: 608 I 608
>gi|239748581 PREDICTED: ankyrin repeat domain 31 [Homo sapiens]
Length = 1873
Score = 84.7 bits (208), Expect = 7e-16
Identities = 53/144 (36%), Positives = 76/144 (52%), Gaps = 2/144 (1%)
Query: 1418 EARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLN 1477
+A R+ GE+ L A R G +V +E+ DVN DNAG+ LHEA G ++
Sbjct: 1144 KAGRINKRNARGESQLHLAVRRGNLPLVKALIESG-ADVNLNDNAGWTPLHEASNEGSID 1202
Query: 1478 IVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTH 1537
I+ LL+ GA VNC DG PLHDAV N+HL+ +LL GA+P ++ +
Sbjct: 1203 IIVELLKAGAKVNCENIDGILPLHDAVANNHLKAAEILLQNGANPNQKDQKQKSALDEAD 1262
Query: 1538 SELMEKFLTDY-LNDLQGRNDDDA 1560
E M++ L Y + R++ DA
Sbjct: 1263 DEKMKELLRSYGAIETVNRDESDA 1286
Score = 72.4 bits (176), Expect = 4e-12
Identities = 44/121 (36%), Positives = 62/121 (51%), Gaps = 1/121 (0%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
GE L+ +AA ++V +C++ K +VN AG+ ALHEA G+ LL+ GAD
Sbjct: 489 GENLVYKAALHDDADLVHHCIK-KGGNVNQPSYAGWTALHEASVGGFYRTASELLKGGAD 547
Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDY 1548
VN PLHDAV N H ++ LLL GADP G+ + M++ L Y
Sbjct: 548 VNIKGLYQITPLHDAVMNGHYKVAELLLLNGADPLFRNDDGKCALDEAKDLCMKRLLERY 607
Query: 1549 L 1549
+
Sbjct: 608 I 608
>gi|239742600 PREDICTED: ankyrin repeat domain 31 [Homo sapiens]
Length = 1873
Score = 84.7 bits (208), Expect = 7e-16
Identities = 53/144 (36%), Positives = 76/144 (52%), Gaps = 2/144 (1%)
Query: 1418 EARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLN 1477
+A R+ GE+ L A R G +V +E+ DVN DNAG+ LHEA G ++
Sbjct: 1144 KAGRINKRNARGESQLHLAVRRGNLPLVKALIESG-ADVNLNDNAGWTPLHEASNEGSID 1202
Query: 1478 IVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTH 1537
I+ LL+ GA VNC DG PLHDAV N+HL+ +LL GA+P ++ +
Sbjct: 1203 IIVELLKAGAKVNCENIDGILPLHDAVANNHLKAAEILLQNGANPNQKDQKQKSALDEAD 1262
Query: 1538 SELMEKFLTDY-LNDLQGRNDDDA 1560
E M++ L Y + R++ DA
Sbjct: 1263 DEKMKELLRSYGAIETVNRDESDA 1286
Score = 72.4 bits (176), Expect = 4e-12
Identities = 44/121 (36%), Positives = 62/121 (51%), Gaps = 1/121 (0%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
GE L+ +AA ++V +C++ K +VN AG+ ALHEA G+ LL+ GAD
Sbjct: 489 GENLVYKAALHDDADLVHHCIK-KGGNVNQPSYAGWTALHEASVGGFYRTASELLKGGAD 547
Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDY 1548
VN PLHDAV N H ++ LLL GADP G+ + M++ L Y
Sbjct: 548 VNIKGLYQITPLHDAVMNGHYKVAELLLLNGADPLFRNDDGKCALDEAKDLCMKRLLERY 607
Query: 1549 L 1549
+
Sbjct: 608 I 608
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 75.1 bits (183), Expect = 5e-13
Identities = 62/196 (31%), Positives = 94/196 (47%), Gaps = 15/196 (7%)
Query: 1373 YDLSPAKQEPKPFDRLQQLLPASQSTQLPCSSSPQETTQSRPMPPEA---RRLIVNKN-- 1427
Y LS KQ L + A ++ + P +TT ++ P + ++ VNK
Sbjct: 106 YPLSERKQMA-----LLMQMTARDNSPDSTPNHPSQTTPAQKKTPSSSSRQKDKVNKRNE 160
Query: 1428 AGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGA 1487
GET L AA G + V + +VN +D AG+ LHEAC G+ ++ + L+ GA
Sbjct: 161 RGETPLHMAAIRGDVKQVKELISLG-ANVNVKDFAGWTPLHEACNVGYYDVAKILIAAGA 219
Query: 1488 DVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTD 1547
DVN D PLHD+ + H +IV+LLL +G +P A G + + +E +E L
Sbjct: 220 DVNTQGLDDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPVDVAETEELELLLKR 279
Query: 1548 YLNDLQGRNDDDASGT 1563
+ +DDD S T
Sbjct: 280 EV----PLSDDDESYT 291
Score = 33.5 bits (75), Expect = 1.8
Identities = 63/319 (19%), Positives = 112/319 (35%), Gaps = 23/319 (7%)
Query: 1027 EMKEREGGHPATKDSEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNES-ERCEYSVG 1085
++KE P KDSE + E G + K + +E+ ES E+ E
Sbjct: 746 DLKEERENIPTDKDSEFTSLGMSAIEESIGLHLVE-KEIDIEKQEKHIKESKEKPEKRSQ 804
Query: 1086 NKHRDPFEAPEDKDLPVEKYFVERQPVSEPPAD--QVASDMPHSPTLRVDRKRKVSGDSS 1143
K +D E E K EK + D + + L K +
Sbjct: 805 IKEKD-IEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGE 863
Query: 1144 HTETTAEEVPEDPLLKAKRR--RVSKGLHPKKQRHLLHLRERWEQQVSAADGKPGRQSRK 1201
++ TA D K++ + R P+K+RHL +E+ + S+
Sbjct: 864 KSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKS 923
Query: 1202 EVTQATQPEAIPQGTNITEEKPGRKRAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMKS 1261
E +G N +++ K+ +++ S + + K E+ + G+
Sbjct: 924 E-----------KGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHE 972
Query: 1262 LSSTSAGGKKQAQPSCAPASRPPAKQQKIKENQKTDVLCADEEEDCQAASLLQKYTDNSE 1321
S K + +P P + K+ K + K D+ +D + L K ++
Sbjct: 973 -KPLSLKEKTKDEPLKTPDGKEKDKKDKDIDRYKE----RDKHKDKIQINSLLKLKSEAD 1027
Query: 1322 KPSGKRLCKTKHLIPQESR 1340
KP K +K P+E R
Sbjct: 1028 KPKPKSSPASKDTRPKEKR 1046
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 75.1 bits (183), Expect = 5e-13
Identities = 62/196 (31%), Positives = 94/196 (47%), Gaps = 15/196 (7%)
Query: 1373 YDLSPAKQEPKPFDRLQQLLPASQSTQLPCSSSPQETTQSRPMPPEA---RRLIVNKN-- 1427
Y LS KQ L + A ++ + P +TT ++ P + ++ VNK
Sbjct: 129 YPLSERKQMA-----LLMQMTARDNSPDSTPNHPSQTTPAQKKTPSSSSRQKDKVNKRNE 183
Query: 1428 AGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGA 1487
GET L AA G + V + +VN +D AG+ LHEAC G+ ++ + L+ GA
Sbjct: 184 RGETPLHMAAIRGDVKQVKELISLG-ANVNVKDFAGWTPLHEACNVGYYDVAKILIAAGA 242
Query: 1488 DVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTD 1547
DVN D PLHD+ + H +IV+LLL +G +P A G + + +E +E L
Sbjct: 243 DVNTQGLDDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPVDVAETEELELLLKR 302
Query: 1548 YLNDLQGRNDDDASGT 1563
+ +DDD S T
Sbjct: 303 EV----PLSDDDESYT 314
Score = 33.5 bits (75), Expect = 1.8
Identities = 63/319 (19%), Positives = 112/319 (35%), Gaps = 23/319 (7%)
Query: 1027 EMKEREGGHPATKDSEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNES-ERCEYSVG 1085
++KE P KDSE + E G + K + +E+ ES E+ E
Sbjct: 769 DLKEERENIPTDKDSEFTSLGMSAIEESIGLHLVE-KEIDIEKQEKHIKESKEKPEKRSQ 827
Query: 1086 NKHRDPFEAPEDKDLPVEKYFVERQPVSEPPAD--QVASDMPHSPTLRVDRKRKVSGDSS 1143
K +D E E K EK + D + + L K +
Sbjct: 828 IKEKD-IEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGE 886
Query: 1144 HTETTAEEVPEDPLLKAKRR--RVSKGLHPKKQRHLLHLRERWEQQVSAADGKPGRQSRK 1201
++ TA D K++ + R P+K+RHL +E+ + S+
Sbjct: 887 KSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKS 946
Query: 1202 EVTQATQPEAIPQGTNITEEKPGRKRAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMKS 1261
E +G N +++ K+ +++ S + + K E+ + G+
Sbjct: 947 E-----------KGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHE 995
Query: 1262 LSSTSAGGKKQAQPSCAPASRPPAKQQKIKENQKTDVLCADEEEDCQAASLLQKYTDNSE 1321
S K + +P P + K+ K + K D+ +D + L K ++
Sbjct: 996 -KPLSLKEKTKDEPLKTPDGKEKDKKDKDIDRYKE----RDKHKDKIQINSLLKLKSEAD 1050
Query: 1322 KPSGKRLCKTKHLIPQESR 1340
KP K +K P+E R
Sbjct: 1051 KPKPKSSPASKDTRPKEKR 1069
>gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase 2 [Homo sapiens]
Length = 1166
Score = 71.2 bits (173), Expect = 8e-12
Identities = 48/159 (30%), Positives = 72/159 (45%), Gaps = 2/159 (1%)
Query: 1393 PASQSTQLPCSSSPQETTQSRPMPPEARRLIVNKNAGETLLQRAARLGYEEVVLYCLENK 1452
PA++ C + E + R + PE T L AA G ++VV Y L+N
Sbjct: 23 PAARELFEACRNGDVERVK-RLVTPEKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNG 81
Query: 1453 ICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIV 1512
+V RD+ G LH AC+ G +V LL +GAD N PLH+A +++
Sbjct: 82 -ANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVC 140
Query: 1513 RLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLND 1551
+LL +GA+PT+ GRT + + +Y D
Sbjct: 141 IVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKKD 179
Score = 67.0 bits (162), Expect = 1e-10
Identities = 39/116 (33%), Positives = 62/116 (53%), Gaps = 1/116 (0%)
Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
T L AA EV Y L++ DVN +D G LH A + G +++ L++Y A VN
Sbjct: 681 TPLHLAAGYNNLEVAEYLLQHG-ADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVN 739
Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLT 1546
+ + PLH+A + ++ LLL++GADPTL G+T + + ++ + LT
Sbjct: 740 ATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSADDVSALLT 795
Score = 60.8 bits (146), Expect = 1e-08
Identities = 38/101 (37%), Positives = 51/101 (50%), Gaps = 1/101 (0%)
Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
T L AA VV Y L++ DV+ +D G LH AC+ G + L+++GA VN
Sbjct: 528 TPLHFAAGYNRVSVVEYLLQHG-ADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVN 586
Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
+ PLH+A EI +LLL +GADPT G T
Sbjct: 587 VADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNT 627
Score = 59.7 bits (143), Expect = 2e-08
Identities = 34/107 (31%), Positives = 55/107 (51%), Gaps = 1/107 (0%)
Query: 1440 GYEEV-VLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTR 1498
GY V ++ L DV+ +D LH AC+ G + L+++GA VN
Sbjct: 220 GYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFT 279
Query: 1499 PLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFL 1545
PLH+A + +E+ LLLSYGADPTL ++ + + + +++ L
Sbjct: 280 PLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDLAPTPQLKERL 326
Score = 52.4 bits (124), Expect = 4e-06
Identities = 35/115 (30%), Positives = 54/115 (46%), Gaps = 2/115 (1%)
Query: 1430 ETLLQRAARLGYEEVVLYC--LENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGA 1487
ET L AA Y + C L K ++N + LH A + ++V ++++ A
Sbjct: 365 ETALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEA 424
Query: 1488 DVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELME 1542
VN G LH A HL+ RLLLSYG DP + + G T ++M + + +
Sbjct: 425 KVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTALQMGNENVQQ 479
Score = 50.4 bits (119), Expect = 1e-05
Identities = 32/104 (30%), Positives = 53/104 (50%), Gaps = 1/104 (0%)
Query: 1417 PEARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWL 1476
P A+ ++ + + LL+ +AR G EE ++ L + + D LH A +
Sbjct: 166 PSAKAVLTGEYKKDELLE-SARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRV 224
Query: 1477 NIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGA 1520
IV+ LL++GADV+ + PLH+A H E+ LL+ +GA
Sbjct: 225 KIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGA 268
Score = 44.7 bits (104), Expect = 8e-04
Identities = 40/143 (27%), Positives = 55/143 (38%), Gaps = 55/143 (38%)
Query: 1433 LQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD---- 1488
L A G+ EVV L + D N RDN Y LHEA +G +++ LL++GA+
Sbjct: 95 LHNACSFGHAEVVNLLLRHG-ADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIR 153
Query: 1489 ------------------------------------------------VNCSAQDGTR-- 1498
VNC A DG +
Sbjct: 154 NTDGRTALDLADPSAKAVLTGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKST 213
Query: 1499 PLHDAVENDHLEIVRLLLSYGAD 1521
PLH A + ++IV+LLL +GAD
Sbjct: 214 PLHLAAGYNRVKIVQLLLQHGAD 236
Score = 38.9 bits (89), Expect = 0.044
Identities = 29/83 (34%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
Query: 1433 LQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCS 1492
L A G+ EV +++ VN D + LHEA A+G I + LL++GAD
Sbjct: 563 LHNACSYGHYEVAELLVKHGAV-VNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKK 621
Query: 1493 AQDGTRPLHDAVENDHLEIVRLL 1515
+DG PL D V++ +I LL
Sbjct: 622 NRDGNTPL-DLVKDGDTDIQDLL 643
>gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo
sapiens]
Length = 950
Score = 70.1 bits (170), Expect = 2e-11
Identities = 49/131 (37%), Positives = 65/131 (49%), Gaps = 10/131 (7%)
Query: 1424 VNKNAGETLLQRAARLGYEEVVLYCLENK-----ICDVN----HRDNAGYCALHEACARG 1474
+N A + LL A R G E V LE I D+N + N G+ LH AC G
Sbjct: 1 MNTEAEQQLLHHA-RNGNAEEVRQLLETMARNEVIADINCKGRSKSNLGWTPLHLACYFG 59
Query: 1475 WLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMK 1534
+V+ LL+ GA+VN G PLH A E+V LLL Y AD T+ SG+T +
Sbjct: 60 HRQVVQDLLKAGAEVNVLNDMGDTPLHRAAFTGRKELVMLLLEYNADTTIVNGSGQTAKE 119
Query: 1535 MTHSELMEKFL 1545
+TH+E + L
Sbjct: 120 VTHAEEIRSML 130
Score = 38.9 bits (89), Expect = 0.044
Identities = 42/151 (27%), Positives = 57/151 (37%), Gaps = 30/151 (19%)
Query: 1424 VNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCA-----------LHEACA 1472
V + G+T L RAA G +E+V+ LE D + +G A + EA
Sbjct: 76 VLNDMGDTPLHRAAFTGRKELVMLLLEYN-ADTTIVNGSGQTAKEVTHAEEIRSMLEAVE 134
Query: 1473 RGWLNIVRHLLEYGA------------------DVNCSAQDGTRPLHDAVENDHLEIVRL 1514
R + LL A DVNCS Q G PLH A H +
Sbjct: 135 RTQQRKLEELLLAAAREGKTTELTALLNRPNPPDVNCSDQLGNTPLHCAAYRAHKQCALK 194
Query: 1515 LLSYGADPTLATYSGRTIMKMTHSELMEKFL 1545
LL GADP L + + + + M+ L
Sbjct: 195 LLRSGADPNLKNKNDQKPLDLAQGAEMKHIL 225
>gi|187608777 NF-kappa-B inhibitor-like protein 2 [Homo sapiens]
Length = 1378
Score = 69.3 bits (168), Expect = 3e-11
Identities = 50/127 (39%), Positives = 65/127 (51%), Gaps = 9/127 (7%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGA- 1487
GETLL RA G V L + +N RD G+ LHEAC G L IVR LL++GA
Sbjct: 529 GETLLHRACIEGQLRRV-QDLVRQGHPLNPRDYCGWTPLHEACNYGHLEIVRFLLDHGAA 587
Query: 1488 --DVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFL 1545
D +G PLHDA+ H E+ LLL GA TL T G ++ E +++++
Sbjct: 588 VDDPGGQGCEGITPLHDALNCGHFEVAELLLERGASVTLRTRKG-----LSPLETLQQWV 642
Query: 1546 TDYLNDL 1552
Y DL
Sbjct: 643 KLYRRDL 649
Score = 52.8 bits (125), Expect = 3e-06
Identities = 28/64 (43%), Positives = 35/64 (54%)
Query: 1457 NHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLL 1516
N R++ G LH AC G L V+ L+ G +N G PLH+A HLEIVR LL
Sbjct: 523 NRRNDMGETLLHRACIEGQLRRVQDLVRQGHPLNPRDYCGWTPLHEACNYGHLEIVRFLL 582
Query: 1517 SYGA 1520
+GA
Sbjct: 583 DHGA 586
>gi|14150169 acyl-coenzyme A binding domain containing 6 [Homo
sapiens]
Length = 282
Score = 68.6 bits (166), Expect = 5e-11
Identities = 40/94 (42%), Positives = 48/94 (51%), Gaps = 11/94 (11%)
Query: 1447 YCLENKI-----------CDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQD 1495
YC EN I DVN +D G LH AC RG +V LL++ AD+NC +
Sbjct: 165 YCRENNIDHITKAIKSKNVDVNVKDEEGRALLHWACDRGHKELVTVLLQHRADINCQDNE 224
Query: 1496 GTRPLHDAVENDHLEIVRLLLSYGADPTLATYSG 1529
G LH A + L+IV LLL GADPTL G
Sbjct: 225 GQTALHYASACEFLDIVELLLQSGADPTLRDQDG 258
Score = 50.8 bits (120), Expect = 1e-05
Identities = 31/76 (40%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
Query: 1424 VNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLL 1483
V G LL A G++E+V L+++ D+N +DN G ALH A A +L+IV LL
Sbjct: 187 VKDEEGRALLHWACDRGHKELVTVLLQHR-ADINCQDNEGQTALHYASACEFLDIVELLL 245
Query: 1484 EYGADVNCSAQDGTRP 1499
+ GAD QDG P
Sbjct: 246 QSGADPTLRDQDGCLP 261
Score = 32.7 bits (73), Expect = 3.1
Identities = 17/57 (29%), Positives = 28/57 (49%)
Query: 1477 NIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM 1533
+I + + DVN ++G LH A + H E+V +LL + AD G+T +
Sbjct: 173 HITKAIKSKNVDVNVKDEEGRALLHWACDRGHKELVTVLLQHRADINCQDNEGQTAL 229
>gi|188219549 ankyrin repeat domain 32 [Homo sapiens]
Length = 1058
Score = 67.8 bits (164), Expect = 9e-11
Identities = 39/92 (42%), Positives = 53/92 (57%), Gaps = 1/92 (1%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
GET L RA E ++ L D+N +DNAG+ LHEAC G V+ +L+ +
Sbjct: 807 GETALHRACINNQVEKLILLLSLPGIDINVKDNAGWTPLHEACNYGNTVCVQEILQRCPE 866
Query: 1489 VNCSAQ-DGTRPLHDAVENDHLEIVRLLLSYG 1519
V+ Q DG PLHDA+ N H+EI +LLL +G
Sbjct: 867 VDLLTQVDGVTPLHDALSNGHVEIGKLLLQHG 898
>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
Length = 4377
Score = 67.4 bits (163), Expect = 1e-10
Identities = 47/137 (34%), Positives = 74/137 (54%), Gaps = 9/137 (6%)
Query: 1423 IVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHL 1482
I N+N G L A++ G+ EVV L+ + +V+ G ALH A G +V+ L
Sbjct: 69 ICNQN-GLNALHLASKEGHVEVVSELLQRE-ANVDAATKKGNTALHIASLAGQAEVVKVL 126
Query: 1483 LEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT----IMKMTHS 1538
+ GA+VN +Q+G PL+ A + +HLE+V+ LL GA +LAT G T ++ H
Sbjct: 127 VTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHD 186
Query: 1539 ELMEKFLTDYLNDLQGR 1555
+++ L ND +G+
Sbjct: 187 QVVSLLLE---NDTKGK 200
Score = 60.1 bits (144), Expect = 2e-08
Identities = 37/113 (32%), Positives = 56/113 (49%), Gaps = 7/113 (6%)
Query: 1424 VNKNAGETLLQRAA---RLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVR 1480
++ +G T L AA R+ EV++ N+ V+ + GY LH C G + IV
Sbjct: 692 LSNKSGLTPLHLAAQEDRVNVAEVLV----NQGAHVDAQTKMGYTPLHVGCHYGNIKIVN 747
Query: 1481 HLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM 1533
LL++ A VN ++G PLH A + H I+ +LL A P T +G T +
Sbjct: 748 FLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTAL 800
Score = 57.4 bits (137), Expect = 1e-07
Identities = 32/105 (30%), Positives = 51/105 (48%), Gaps = 1/105 (0%)
Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
T L AA G+ +V L+ K + N + G+ LH AC + + ++ LL++GA +
Sbjct: 369 TALHVAAHCGHYKVAKVLLDKK-ANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQ 427
Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKM 1535
+ G P+H A H+ IV L+ +GA P G T + M
Sbjct: 428 AVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHM 472
Score = 57.4 bits (137), Expect = 1e-07
Identities = 41/124 (33%), Positives = 61/124 (49%), Gaps = 4/124 (3%)
Query: 1428 AGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGA 1487
+G T + AA +G+ +V + + N + G ALH A G +VR+L++ GA
Sbjct: 432 SGLTPIHVAAFMGHVNIVSQLMHHG-ASPNTTNVRGETALHMAARSGQAEVVRYLVQDGA 490
Query: 1488 DVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELME---KF 1544
V A+D PLH + +IV+ LL GA P AT SG T + ++ E E F
Sbjct: 491 QVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAF 550
Query: 1545 LTDY 1548
L D+
Sbjct: 551 LLDH 554
Score = 56.6 bits (135), Expect = 2e-07
Identities = 41/130 (31%), Positives = 60/130 (46%), Gaps = 9/130 (6%)
Query: 1418 EARRLIVNKNA--------GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHE 1469
E L++ K+A G T L AA ++V L L+ N GY LH
Sbjct: 579 EVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKN-GYTPLHI 637
Query: 1470 ACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSG 1529
A + ++I LLEYGAD N + G +H A + H+++V LLL A+ L+ SG
Sbjct: 638 AAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSG 697
Query: 1530 RTIMKMTHSE 1539
T + + E
Sbjct: 698 LTPLHLAAQE 707
Score = 55.1 bits (131), Expect = 6e-07
Identities = 34/102 (33%), Positives = 51/102 (50%), Gaps = 1/102 (0%)
Query: 1430 ETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADV 1489
+T L +ARLG ++V L+ N +GY LH + G ++ LL++GA +
Sbjct: 500 QTPLHISARLGKADIVQQLLQQG-ASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASL 558
Query: 1490 NCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
+ + + G PLH A + LE+ LLL A P A SG T
Sbjct: 559 SITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLT 600
Score = 54.3 bits (129), Expect = 1e-06
Identities = 33/104 (31%), Positives = 52/104 (50%), Gaps = 1/104 (0%)
Query: 1428 AGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGA 1487
+G T L +AR G+E+V + L++ ++ G+ LH A G L + LL+ A
Sbjct: 531 SGYTPLHLSAREGHEDVAAFLLDHG-ASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSA 589
Query: 1488 DVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
+ + + G PLH A D+ ++ LLL GA P A +G T
Sbjct: 590 SPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYT 633
Score = 53.9 bits (128), Expect = 1e-06
Identities = 43/160 (26%), Positives = 78/160 (48%), Gaps = 10/160 (6%)
Query: 1392 LPASQSTQLPCSSSPQETTQSRPMPPEARRLIVNKNAGETLLQRAARLGYEEVVLYCLEN 1451
L ++ ++ P++ + R + ++ K+ RAAR G+ E L ++N
Sbjct: 8 LKKNRDLEINAEEEPEKKRKHRKRSRDRKK----KSDANASYLRAARAGHLEKALDYIKN 63
Query: 1452 KICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEI 1511
+ D+N + G ALH A G + +V LL+ A+V+ + + G LH A E+
Sbjct: 64 GV-DINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEV 122
Query: 1512 VRLLLSYGADPTLATYSGRTIMKM----THSELMEKFLTD 1547
V++L++ GA+ + +G T + M H E++ KFL D
Sbjct: 123 VKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVV-KFLLD 161
Score = 50.1 bits (118), Expect = 2e-05
Identities = 35/112 (31%), Positives = 51/112 (45%), Gaps = 1/112 (0%)
Query: 1424 VNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLL 1483
V +G T L AA G V L N+ V+ LH A RG N+V+ LL
Sbjct: 230 VESKSGFTPLHIAAHYGNINVATLLL-NRAAAVDFTARNDITPLHVASKRGNANMVKLLL 288
Query: 1484 EYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKM 1535
+ GA ++ +DG PLH + H ++V +LL A T +G + + M
Sbjct: 289 DRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHM 340
Score = 47.0 bits (110), Expect = 2e-04
Identities = 32/103 (31%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
G T L AA+ ++ LE D N G ++H A G +++V LL A+
Sbjct: 631 GYTPLHIAAKKNQMDIATTLLEYG-ADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNAN 689
Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
VN S + G PLH A + D + + +L++ GA T G T
Sbjct: 690 VNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYT 732
Score = 43.1 bits (100), Expect = 0.002
Identities = 31/103 (30%), Positives = 47/103 (45%), Gaps = 1/103 (0%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
G T L AR G+E+VV L+ + + + G LH A LN V+ LL++
Sbjct: 301 GLTPLHCGARSGHEQVVEMLLD-RAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVP 359
Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
V+ D LH A H ++ ++LL A+P +G T
Sbjct: 360 VDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFT 402
Score = 42.4 bits (98), Expect = 0.004
Identities = 28/96 (29%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 1436 AARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQD 1495
AA+ G+ ++V L + +VN + +G LH A +N+ L+ GA V+ +
Sbjct: 671 AAQEGHVDMVSLLL-GRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKM 729
Query: 1496 GTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
G PLH +++IV LL + A T +G T
Sbjct: 730 GYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYT 765
Score = 40.4 bits (93), Expect = 0.015
Identities = 29/89 (32%), Positives = 41/89 (46%), Gaps = 3/89 (3%)
Query: 1431 TLLQRAARLGYEEVVLYCLENKI-CDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADV 1489
T L A++ G +V L+ D RD G LH G +V LL+ A +
Sbjct: 270 TPLHVASKRGNANMVKLLLDRGAKIDAKTRD--GLTPLHCGARSGHEQVVEMLLDRAAPI 327
Query: 1490 NCSAQDGTRPLHDAVENDHLEIVRLLLSY 1518
++G PLH A + DHL V+LLL +
Sbjct: 328 LSKTKNGLSPLHMATQGDHLNCVQLLLQH 356
Score = 37.0 bits (84), Expect = 0.17
Identities = 40/169 (23%), Positives = 67/169 (39%), Gaps = 16/169 (9%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
G T L G ++V + L++ VN + GY LH+A +G +I+ LL+ A
Sbjct: 730 GYTPLHVGCHYGNIKIVNFLLQHS-AKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNAS 788
Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDY 1548
N +G N L I R L TL + T+ T +E + + +
Sbjct: 789 PNELTVNG---------NTALGIARRLGYISVVDTLKIVTEETMTTTTVTEKHKMNVPET 839
Query: 1549 LNDLQGRNDDDA--SGTWDFYGSSVCEPDDESGYDVLANPP----GPED 1591
+N++ +DD+ + + D E G D + GP+D
Sbjct: 840 MNEVLDMSDDEVRKANAPEMLSDGEYISDVEEGEDAMTGDTDKYLGPQD 888
Score = 32.0 bits (71), Expect = 5.3
Identities = 25/92 (27%), Positives = 41/92 (44%), Gaps = 5/92 (5%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
G T L A + G+++VV LEN + + ALH A + LL+ +
Sbjct: 173 GFTPLAVALQQGHDQVVSLLLEN-----DTKGKVRLPALHIAARKDDTKAAALLLQNDNN 227
Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGA 1520
+ ++ G PLH A ++ + LLL+ A
Sbjct: 228 ADVESKSGFTPLHIAAHYGNINVATLLLNRAA 259
Score = 31.2 bits (69), Expect = 9.1
Identities = 35/122 (28%), Positives = 56/122 (45%), Gaps = 10/122 (8%)
Query: 503 STAPSSWVVPGPSPNEENNGKSMSLKNKAL-DWAIPQQ--RSSSCPRMGGTDAVITNV-- 557
S S W V PSP + G S + K++ D A P + R+ S P N+
Sbjct: 1535 SPLKSIWSVSTPSPIKSTLGASTTSSVKSISDVASPIRSFRTMSSPIKTVVSQSPYNIQV 1594
Query: 558 -SGSVSSAGRPASASPAPNANADGTKTSRSS-VETTPSVIQHVG---QPPATPAKHSSST 612
SG+++ A A+P ++ T +SR+S V T S+++ PPA+P + +
Sbjct: 1595 SSGTLARAPAVTEATPLKGLASNSTFSSRTSPVTTAGSLLERSSITMTPPASPKSNINMY 1654
Query: 613 SS 614
SS
Sbjct: 1655 SS 1656
>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
Length = 983
Score = 66.6 bits (161), Expect = 2e-10
Identities = 40/107 (37%), Positives = 57/107 (53%), Gaps = 1/107 (0%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
G + L AA+ + E + L++K C D++G ALH A A+G L V+ L E+ +
Sbjct: 89 GHSALHLAAKNSHHECIRKLLQSK-CPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSP 147
Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKM 1535
+N DG PL AV+N H EI LL +GAD SGRT + +
Sbjct: 148 INLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALML 194
Score = 49.7 bits (117), Expect = 2e-05
Identities = 32/107 (29%), Positives = 45/107 (42%)
Query: 1427 NAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYG 1486
N + L +A G E V L K D+ G A H A A+G + +R ++ +G
Sbjct: 20 NKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHG 79
Query: 1487 ADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM 1533
DV G LH A +N H E +R LL SG+T +
Sbjct: 80 VDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTAL 126
Score = 43.5 bits (101), Expect = 0.002
Identities = 31/89 (34%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
G L A + G+ E+ + L++ DVN R+ +G AL AC G N V L++ GAD
Sbjct: 155 GNIPLLLAVQNGHSEICHFLLDHG-ADVNSRNKSGRTALMLACEIGSSNAVEALIKKGAD 213
Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLS 1517
+N G LH + +++ I LLLS
Sbjct: 214 LNLVDSLGYNALHYSKLSENAGIQSLLLS 242
Score = 41.2 bits (95), Expect = 0.009
Identities = 34/103 (33%), Positives = 45/103 (43%), Gaps = 1/103 (0%)
Query: 1427 NAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYG 1486
++G+T L AA G + V E+K +N +D G L A G I LL++G
Sbjct: 120 SSGKTALHYAAAQGCLQAVQILCEHK-SPINLKDLDGNIPLLLAVQNGHSEICHFLLDHG 178
Query: 1487 ADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSG 1529
ADVN + G L A E V L+ GAD L G
Sbjct: 179 ADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLG 221
Score = 32.3 bits (72), Expect = 4.1
Identities = 27/101 (26%), Positives = 44/101 (43%), Gaps = 9/101 (8%)
Query: 1450 ENKICDVNHRDNAGYCALHEACARGWLNIVRHLL-EYGADVNCSAQDGTRPLHDAVENDH 1508
E K + N D+ L +A G V LL + GA +G H A H
Sbjct: 13 EKKTNEWNKNDDR----LLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGH 68
Query: 1509 LEIVRLLLSYGADPTLATYSGRTIM----KMTHSELMEKFL 1545
+E +R+++++G D T +G + + K +H E + K L
Sbjct: 69 VECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLL 109
>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
Length = 972
Score = 66.6 bits (161), Expect = 2e-10
Identities = 40/107 (37%), Positives = 57/107 (53%), Gaps = 1/107 (0%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
G + L AA+ + E + L++K C D++G ALH A A+G L V+ L E+ +
Sbjct: 78 GHSALHLAAKNSHHECIRKLLQSK-CPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSP 136
Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKM 1535
+N DG PL AV+N H EI LL +GAD SGRT + +
Sbjct: 137 INLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALML 183
Score = 49.7 bits (117), Expect = 2e-05
Identities = 32/107 (29%), Positives = 45/107 (42%)
Query: 1427 NAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYG 1486
N + L +A G E V L K D+ G A H A A+G + +R ++ +G
Sbjct: 9 NKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHG 68
Query: 1487 ADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM 1533
DV G LH A +N H E +R LL SG+T +
Sbjct: 69 VDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTAL 115
Score = 43.5 bits (101), Expect = 0.002
Identities = 31/89 (34%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
G L A + G+ E+ + L++ DVN R+ +G AL AC G N V L++ GAD
Sbjct: 144 GNIPLLLAVQNGHSEICHFLLDHG-ADVNSRNKSGRTALMLACEIGSSNAVEALIKKGAD 202
Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLS 1517
+N G LH + +++ I LLLS
Sbjct: 203 LNLVDSLGYNALHYSKLSENAGIQSLLLS 231
Score = 41.2 bits (95), Expect = 0.009
Identities = 34/103 (33%), Positives = 45/103 (43%), Gaps = 1/103 (0%)
Query: 1427 NAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYG 1486
++G+T L AA G + V E+K +N +D G L A G I LL++G
Sbjct: 109 SSGKTALHYAAAQGCLQAVQILCEHK-SPINLKDLDGNIPLLLAVQNGHSEICHFLLDHG 167
Query: 1487 ADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSG 1529
ADVN + G L A E V L+ GAD L G
Sbjct: 168 ADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLG 210
Score = 32.3 bits (72), Expect = 4.1
Identities = 27/102 (26%), Positives = 45/102 (44%), Gaps = 9/102 (8%)
Query: 1449 LENKICDVNHRDNAGYCALHEACARGWLNIVRHLL-EYGADVNCSAQDGTRPLHDAVEND 1507
+E K + N D+ L +A G V LL + GA +G H A
Sbjct: 1 MEAKTNEWNKNDDR----LLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKG 56
Query: 1508 HLEIVRLLLSYGADPTLATYSGRTIM----KMTHSELMEKFL 1545
H+E +R+++++G D T +G + + K +H E + K L
Sbjct: 57 HVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLL 98
>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
Length = 951
Score = 66.6 bits (161), Expect = 2e-10
Identities = 40/107 (37%), Positives = 57/107 (53%), Gaps = 1/107 (0%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
G + L AA+ + E + L++K C D++G ALH A A+G L V+ L E+ +
Sbjct: 86 GHSALHLAAKNSHHECIRKLLQSK-CPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSP 144
Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKM 1535
+N DG PL AV+N H EI LL +GAD SGRT + +
Sbjct: 145 INLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALML 191
Score = 49.7 bits (117), Expect = 2e-05
Identities = 32/107 (29%), Positives = 45/107 (42%)
Query: 1427 NAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYG 1486
N + L +A G E V L K D+ G A H A A+G + +R ++ +G
Sbjct: 17 NKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHG 76
Query: 1487 ADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM 1533
DV G LH A +N H E +R LL SG+T +
Sbjct: 77 VDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTAL 123
Score = 43.5 bits (101), Expect = 0.002
Identities = 31/89 (34%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
G L A + G+ E+ + L++ DVN R+ +G AL AC G N V L++ GAD
Sbjct: 152 GNIPLLLAVQNGHSEICHFLLDHG-ADVNSRNKSGRTALMLACEIGSSNAVEALIKKGAD 210
Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLS 1517
+N G LH + +++ I LLLS
Sbjct: 211 LNLVDSLGYNALHYSKLSENAGIQSLLLS 239
Score = 41.2 bits (95), Expect = 0.009
Identities = 34/103 (33%), Positives = 45/103 (43%), Gaps = 1/103 (0%)
Query: 1427 NAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYG 1486
++G+T L AA G + V E+K +N +D G L A G I LL++G
Sbjct: 117 SSGKTALHYAAAQGCLQAVQILCEHK-SPINLKDLDGNIPLLLAVQNGHSEICHFLLDHG 175
Query: 1487 ADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSG 1529
ADVN + G L A E V L+ GAD L G
Sbjct: 176 ADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLG 218
Score = 32.0 bits (71), Expect = 5.3
Identities = 17/64 (26%), Positives = 30/64 (46%), Gaps = 4/64 (6%)
Query: 1486 GADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM----KMTHSELM 1541
GA +G H A H+E +R+++++G D T +G + + K +H E +
Sbjct: 43 GASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECI 102
Query: 1542 EKFL 1545
K L
Sbjct: 103 RKLL 106
>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 66.6 bits (161), Expect = 2e-10
Identities = 40/107 (37%), Positives = 57/107 (53%), Gaps = 1/107 (0%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
G + L AA+ + E + L++K C D++G ALH A A+G L V+ L E+ +
Sbjct: 86 GHSALHLAAKNSHHECIRKLLQSK-CPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSP 144
Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKM 1535
+N DG PL AV+N H EI LL +GAD SGRT + +
Sbjct: 145 INLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALML 191
Score = 49.7 bits (117), Expect = 2e-05
Identities = 32/107 (29%), Positives = 45/107 (42%)
Query: 1427 NAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYG 1486
N + L +A G E V L K D+ G A H A A+G + +R ++ +G
Sbjct: 17 NKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHG 76
Query: 1487 ADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM 1533
DV G LH A +N H E +R LL SG+T +
Sbjct: 77 VDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTAL 123
Score = 43.5 bits (101), Expect = 0.002
Identities = 31/89 (34%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
G L A + G+ E+ + L++ DVN R+ +G AL AC G N V L++ GAD
Sbjct: 152 GNIPLLLAVQNGHSEICHFLLDHG-ADVNSRNKSGRTALMLACEIGSSNAVEALIKKGAD 210
Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLS 1517
+N G LH + +++ I LLLS
Sbjct: 211 LNLVDSLGYNALHYSKLSENAGIQSLLLS 239
Score = 41.2 bits (95), Expect = 0.009
Identities = 34/103 (33%), Positives = 45/103 (43%), Gaps = 1/103 (0%)
Query: 1427 NAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYG 1486
++G+T L AA G + V E+K +N +D G L A G I LL++G
Sbjct: 117 SSGKTALHYAAAQGCLQAVQILCEHK-SPINLKDLDGNIPLLLAVQNGHSEICHFLLDHG 175
Query: 1487 ADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSG 1529
ADVN + G L A E V L+ GAD L G
Sbjct: 176 ADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLG 218
Score = 32.0 bits (71), Expect = 5.3
Identities = 17/64 (26%), Positives = 30/64 (46%), Gaps = 4/64 (6%)
Query: 1486 GADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM----KMTHSELM 1541
GA +G H A H+E +R+++++G D T +G + + K +H E +
Sbjct: 43 GASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECI 102
Query: 1542 EKFL 1545
K L
Sbjct: 103 RKLL 106
>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 66.6 bits (161), Expect = 2e-10
Identities = 40/107 (37%), Positives = 57/107 (53%), Gaps = 1/107 (0%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
G + L AA+ + E + L++K C D++G ALH A A+G L V+ L E+ +
Sbjct: 86 GHSALHLAAKNSHHECIRKLLQSK-CPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSP 144
Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKM 1535
+N DG PL AV+N H EI LL +GAD SGRT + +
Sbjct: 145 INLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALML 191
Score = 49.7 bits (117), Expect = 2e-05
Identities = 32/107 (29%), Positives = 45/107 (42%)
Query: 1427 NAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYG 1486
N + L +A G E V L K D+ G A H A A+G + +R ++ +G
Sbjct: 17 NKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHG 76
Query: 1487 ADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM 1533
DV G LH A +N H E +R LL SG+T +
Sbjct: 77 VDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTAL 123
Score = 43.5 bits (101), Expect = 0.002
Identities = 31/89 (34%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
G L A + G+ E+ + L++ DVN R+ +G AL AC G N V L++ GAD
Sbjct: 152 GNIPLLLAVQNGHSEICHFLLDHG-ADVNSRNKSGRTALMLACEIGSSNAVEALIKKGAD 210
Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLS 1517
+N G LH + +++ I LLLS
Sbjct: 211 LNLVDSLGYNALHYSKLSENAGIQSLLLS 239
Score = 41.2 bits (95), Expect = 0.009
Identities = 34/103 (33%), Positives = 45/103 (43%), Gaps = 1/103 (0%)
Query: 1427 NAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYG 1486
++G+T L AA G + V E+K +N +D G L A G I LL++G
Sbjct: 117 SSGKTALHYAAAQGCLQAVQILCEHK-SPINLKDLDGNIPLLLAVQNGHSEICHFLLDHG 175
Query: 1487 ADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSG 1529
ADVN + G L A E V L+ GAD L G
Sbjct: 176 ADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLG 218
Score = 32.0 bits (71), Expect = 5.3
Identities = 17/64 (26%), Positives = 30/64 (46%), Gaps = 4/64 (6%)
Query: 1486 GADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM----KMTHSELM 1541
GA +G H A H+E +R+++++G D T +G + + K +H E +
Sbjct: 43 GASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECI 102
Query: 1542 EKFL 1545
K L
Sbjct: 103 RKLL 106
>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 66.6 bits (161), Expect = 2e-10
Identities = 40/107 (37%), Positives = 57/107 (53%), Gaps = 1/107 (0%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
G + L AA+ + E + L++K C D++G ALH A A+G L V+ L E+ +
Sbjct: 86 GHSALHLAAKNSHHECIRKLLQSK-CPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSP 144
Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKM 1535
+N DG PL AV+N H EI LL +GAD SGRT + +
Sbjct: 145 INLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALML 191
Score = 49.7 bits (117), Expect = 2e-05
Identities = 32/107 (29%), Positives = 45/107 (42%)
Query: 1427 NAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYG 1486
N + L +A G E V L K D+ G A H A A+G + +R ++ +G
Sbjct: 17 NKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHG 76
Query: 1487 ADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM 1533
DV G LH A +N H E +R LL SG+T +
Sbjct: 77 VDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTAL 123
Score = 43.5 bits (101), Expect = 0.002
Identities = 31/89 (34%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
G L A + G+ E+ + L++ DVN R+ +G AL AC G N V L++ GAD
Sbjct: 152 GNIPLLLAVQNGHSEICHFLLDHG-ADVNSRNKSGRTALMLACEIGSSNAVEALIKKGAD 210
Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLS 1517
+N G LH + +++ I LLLS
Sbjct: 211 LNLVDSLGYNALHYSKLSENAGIQSLLLS 239
Score = 41.2 bits (95), Expect = 0.009
Identities = 34/103 (33%), Positives = 45/103 (43%), Gaps = 1/103 (0%)
Query: 1427 NAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYG 1486
++G+T L AA G + V E+K +N +D G L A G I LL++G
Sbjct: 117 SSGKTALHYAAAQGCLQAVQILCEHK-SPINLKDLDGNIPLLLAVQNGHSEICHFLLDHG 175
Query: 1487 ADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSG 1529
ADVN + G L A E V L+ GAD L G
Sbjct: 176 ADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLG 218
Score = 32.0 bits (71), Expect = 5.3
Identities = 17/64 (26%), Positives = 30/64 (46%), Gaps = 4/64 (6%)
Query: 1486 GADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM----KMTHSELM 1541
GA +G H A H+E +R+++++G D T +G + + K +H E +
Sbjct: 43 GASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECI 102
Query: 1542 EKFL 1545
K L
Sbjct: 103 RKLL 106
>gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase [Homo sapiens]
Length = 1327
Score = 66.6 bits (161), Expect = 2e-10
Identities = 38/108 (35%), Positives = 57/108 (52%), Gaps = 1/108 (0%)
Query: 1440 GYEEV-VLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTR 1498
GY V ++ L DV+ +D G LH AC+ G + LL++GA VN
Sbjct: 378 GYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFT 437
Query: 1499 PLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLT 1546
PLH+A + +E+ LLLS+GADPTL G++ + M + + + LT
Sbjct: 438 PLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLT 485
Score = 65.9 bits (159), Expect = 3e-10
Identities = 39/117 (33%), Positives = 61/117 (52%), Gaps = 1/117 (0%)
Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
T L AA EV Y LE+ DVN +D G LH A + G ++I L++Y VN
Sbjct: 839 TPLHLAAGYNNLEVAEYLLEHG-ADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVN 897
Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTD 1547
+ + PLH+A + ++ LLL++GADPT+ G+T + + ++ + L D
Sbjct: 898 ATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATADDIRALLID 954
Score = 61.2 bits (147), Expect = 8e-09
Identities = 43/124 (34%), Positives = 61/124 (49%), Gaps = 6/124 (4%)
Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
T L AA VV Y L + DV+ +D G LH AC+ G + L+ +GA VN
Sbjct: 686 TPLHFAAGYNRVSVVEYLLHHG-ADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVN 744
Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLN 1550
+ PLH+A EI +LLL +GADPT G T + +L+++ TD +
Sbjct: 745 VADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPL-----DLVKEGDTDIQD 799
Query: 1551 DLQG 1554
L+G
Sbjct: 800 LLRG 803
Score = 58.9 bits (141), Expect = 4e-08
Identities = 36/119 (30%), Positives = 57/119 (47%), Gaps = 1/119 (0%)
Query: 1433 LQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCS 1492
L AA G ++VV + L+ +V+ RD+ G LH AC+ G +V LL GAD N
Sbjct: 220 LHFAAGFGRKDVVEHLLQMG-ANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNAR 278
Query: 1493 AQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLND 1551
PLH+A +++ +LL +GADP + G++ + + +Y D
Sbjct: 279 DNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKD 337
Score = 55.5 bits (132), Expect = 5e-07
Identities = 35/104 (33%), Positives = 54/104 (51%), Gaps = 1/104 (0%)
Query: 1417 PEARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWL 1476
P A+ ++ + + LL+ AAR G EE ++ L + + D LH A +
Sbjct: 324 PSAKAVLTGEYKKDELLE-AARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRV 382
Query: 1477 NIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGA 1520
IV+ LL++GADV+ + G PLH+A H E+ LLL +GA
Sbjct: 383 RIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGA 426
Score = 51.2 bits (121), Expect = 8e-06
Identities = 32/99 (32%), Positives = 53/99 (53%), Gaps = 1/99 (1%)
Query: 1449 LENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDH 1508
L K +VN ++ LH A R +++ L ++GA +N G LH A H
Sbjct: 544 LLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGH 603
Query: 1509 LEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTD 1547
L+ RLLLSYG+DP++ + G T +M +E +++ L++
Sbjct: 604 LQTCRLLLSYGSDPSIISLQGFTAAQM-GNEAVQQILSE 641
Score = 48.1 bits (113), Expect = 7e-05
Identities = 32/95 (33%), Positives = 50/95 (52%), Gaps = 4/95 (4%)
Query: 1433 LQRAARLGYEEVVLYCLENKICDVNHRDNAGYCA--LHEACARGWLNIVRHLLEYGADVN 1490
L A++ G E V ++ +VN RD G + LH A +++V +LL +GADV+
Sbjct: 654 LLEASKAGDLETVKQLCSSQ--NVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVH 711
Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLA 1525
+ G PLH+A H E+ LL+ +GA +A
Sbjct: 712 AKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVA 746
Score = 44.3 bits (103), Expect = 0.001
Identities = 41/143 (28%), Positives = 53/143 (37%), Gaps = 55/143 (38%)
Query: 1433 LQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD---- 1488
L A G+ EVV L D N RDN Y LHEA +G +++ LL++GAD
Sbjct: 253 LHNACSFGHAEVVSLLLCQG-ADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIR 311
Query: 1489 ------------------------------------------------VNCSAQDGTR-- 1498
VNC A DG +
Sbjct: 312 NTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKST 371
Query: 1499 PLHDAVENDHLEIVRLLLSYGAD 1521
PLH A + + IV+LLL +GAD
Sbjct: 372 PLHLAAGYNRVRIVQLLLQHGAD 394
Score = 33.9 bits (76), Expect = 1.4
Identities = 31/112 (27%), Positives = 42/112 (37%), Gaps = 14/112 (12%)
Query: 1393 PASQSTQLPCSSSPQETTQSRPMPPEARRLIVNKNAGE--------TLLQRAARLGYEEV 1444
P S T L C+ P + L++ K A T L AA + +V
Sbjct: 519 PQSHETALHCA-----VASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDV 573
Query: 1445 VLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDG 1496
+ L +N D G ALH A G L R LL YG+D + + G
Sbjct: 574 -MEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQG 624
Score = 32.0 bits (71), Expect = 5.3
Identities = 40/121 (33%), Positives = 45/121 (37%), Gaps = 19/121 (15%)
Query: 559 GSVSSAGRPASASPAPNANADGTKTSRSSVETTPSVIQHVGQPPATPAKHSSSTSSKGAK 618
GS RP S P DGT S +T S I V P PA STSS
Sbjct: 70 GSRDPPDRPRSPDPV-----DGT-----SCCSTTSTICTVAAAPVVPAV---STSSAAGV 116
Query: 619 ASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLPYPAPEGI-AVSPLSLHGKG 677
A NP S N P SS SP + S P S P G+ + +PL G
Sbjct: 117 APNPAGS---GSNNSPSSS--SSPTSSSSSSPSSPGSSLAESPEAAGVSSTAPLGPGAAG 171
Query: 678 P 678
P
Sbjct: 172 P 172
>gi|215598574 ankyrin 1 isoform 9 [Homo sapiens]
Length = 1897
Score = 65.1 bits (157), Expect = 6e-10
Identities = 39/118 (33%), Positives = 63/118 (53%), Gaps = 1/118 (0%)
Query: 1433 LQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCS 1492
L A++ G+ ++V+ L +I + G ALH A G +VR L+ YGA+VN
Sbjct: 82 LHLASKEGHVKMVVELLHKEII-LETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQ 140
Query: 1493 AQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLN 1550
+Q G PL+ A + +HLE+V+ LL GA+ +AT G T + + + E + +N
Sbjct: 141 SQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLIN 198
Score = 61.2 bits (147), Expect = 8e-09
Identities = 39/104 (37%), Positives = 54/104 (51%), Gaps = 1/104 (0%)
Query: 1428 AGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGA 1487
AG T L AAR G+ E VL LE + G+ LH A G + + LLE A
Sbjct: 535 AGHTPLHIAAREGHVETVLALLEKEASQAC-MTKKGFTPLHVAAKYGKVRVAELLLERDA 593
Query: 1488 DVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
N + ++G PLH AV +++L+IV+LLL G P ++G T
Sbjct: 594 HPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYT 637
Score = 58.5 bits (140), Expect = 5e-08
Identities = 36/108 (33%), Positives = 54/108 (50%), Gaps = 1/108 (0%)
Query: 1424 VNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLL 1483
+ +G T L A+ G+ V +++ + V+ GY LH A G + +V+ LL
Sbjct: 696 LGNKSGLTPLHLVAQEGHVPVADVLIKHGVM-VDATTRMGYTPLHVASHYGNIKLVKFLL 754
Query: 1484 EYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
++ ADVN + G PLH A + H +IV LLL GA P + G T
Sbjct: 755 QHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTT 802
Score = 57.8 bits (138), Expect = 9e-08
Identities = 40/102 (39%), Positives = 48/102 (47%), Gaps = 1/102 (0%)
Query: 1430 ETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADV 1489
ET L AAR G+ EV Y L+NK VN + LH A G N+V+ LLE A+
Sbjct: 471 ETPLHMAARAGHTEVAKYLLQNK-AKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANP 529
Query: 1490 NCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
N + G PLH A H+E V LL A T G T
Sbjct: 530 NLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFT 571
Score = 55.5 bits (132), Expect = 5e-07
Identities = 34/91 (37%), Positives = 49/91 (53%), Gaps = 1/91 (1%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
G T L AA G +EVV L N +VN + G+ L+ A L +V+ LLE GA+
Sbjct: 111 GNTALHIAALAGQDEVVRE-LVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGAN 169
Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYG 1519
N + +DG PL A++ H +V L++YG
Sbjct: 170 QNVATEDGFTPLAVALQQGHENVVAHLINYG 200
Score = 55.5 bits (132), Expect = 5e-07
Identities = 29/77 (37%), Positives = 39/77 (50%)
Query: 1463 GYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADP 1522
GY LH A + + + R LL+YG N + G PLH A + H E+V LLLS A+
Sbjct: 635 GYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANG 694
Query: 1523 TLATYSGRTIMKMTHSE 1539
L SG T + + E
Sbjct: 695 NLGNKSGLTPLHLVAQE 711
Score = 54.7 bits (130), Expect = 8e-07
Identities = 41/133 (30%), Positives = 61/133 (45%), Gaps = 6/133 (4%)
Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
T L AA G+ V L+ K N R G+ LH AC + + ++ LL+ GA ++
Sbjct: 373 TPLHVAAHCGHHRVAKVLLD-KGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASID 431
Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMT----HSELMEKFLT 1546
+ G PLH A HL IV+ LL GA P ++ T + M H+E + K+L
Sbjct: 432 AVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTE-VAKYLL 490
Query: 1547 DYLNDLQGRNDDD 1559
+ + DD
Sbjct: 491 QNKAKVNAKAKDD 503
Score = 54.3 bits (129), Expect = 1e-06
Identities = 44/140 (31%), Positives = 61/140 (43%), Gaps = 9/140 (6%)
Query: 1430 ETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADV 1489
+T L AAR+G+ +V LEN + N AG+ LH A G + V LLE A
Sbjct: 504 QTPLHCAARIGHTNMVKLLLENN-ANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQ 562
Query: 1490 NCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMT--HSELMEKFLTD 1547
C + G PLH A + + + LLL A P A +G T + + H+ L D
Sbjct: 563 ACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNL------D 616
Query: 1548 YLNDLQGRNDDDASGTWDFY 1567
+ L R S W+ Y
Sbjct: 617 IVKLLLPRGGSPHSPAWNGY 636
Score = 52.8 bits (125), Expect = 3e-06
Identities = 40/113 (35%), Positives = 53/113 (46%), Gaps = 3/113 (2%)
Query: 1424 VNKNAGETLLQRAARLGYEEV-VLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHL 1482
V G T L AA YE + V L N+ VN G LH A RG + +VR L
Sbjct: 234 VLSKTGFTPLHIAAH--YENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLL 291
Query: 1483 LEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKM 1535
L+ GA + +D PLH A N H+ I +LL +GA T +G + + M
Sbjct: 292 LDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHM 344
Score = 52.8 bits (125), Expect = 3e-06
Identities = 28/73 (38%), Positives = 39/73 (53%)
Query: 1467 LHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLAT 1526
LH A G + ++LL+ A VN A+D PLH A H +V+LLL A+P LAT
Sbjct: 474 LHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLAT 533
Query: 1527 YSGRTIMKMTHSE 1539
+G T + + E
Sbjct: 534 TAGHTPLHIAARE 546
Score = 51.2 bits (121), Expect = 8e-06
Identities = 33/109 (30%), Positives = 55/109 (50%), Gaps = 9/109 (8%)
Query: 1421 RLIVNKNA--------GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACA 1472
+L++N+ A G T L A+R G +++ L ++ + + LH A
Sbjct: 256 QLLLNRGASVNFTPQNGITPLHIASRRG-NVIMVRLLLDRGAQIETKTKDELTPLHCAAR 314
Query: 1473 RGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGAD 1521
G + I LL++GA + ++G P+H A + DHL+ VRLLL Y A+
Sbjct: 315 NGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAE 363
Score = 48.1 bits (113), Expect = 7e-05
Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 6/137 (4%)
Query: 1418 EARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLN 1477
EA + + K G T L AA+ G V LE N G LH A L+
Sbjct: 559 EASQACMTKK-GFTPLHVAAKYGKVRVAELLLERD-AHPNAAGKNGLTPLHVAVHHNNLD 616
Query: 1478 IVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMT- 1536
IV+ LL G + A +G PLH A + + +E+ R LL YG + G T + +
Sbjct: 617 IVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAA 676
Query: 1537 ---HSELMEKFLTDYLN 1550
H+E++ L+ N
Sbjct: 677 QEGHAEMVALLLSKQAN 693
Score = 47.4 bits (111), Expect = 1e-04
Identities = 30/87 (34%), Positives = 47/87 (54%), Gaps = 1/87 (1%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
G T L A+ G ++V + L+++ DVN + GY LH+A +G +IV LL+ GA
Sbjct: 734 GYTPLHVASHYGNIKLVKFLLQHQ-ADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGAS 792
Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLL 1515
N + DGT PL A ++ + +L
Sbjct: 793 PNEVSSDGTTPLAIAKRLGYISVTDVL 819
Score = 46.2 bits (108), Expect = 3e-04
Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 5/119 (4%)
Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
T L AAR G+ + L++ + + G +H A L+ VR LL+Y A+++
Sbjct: 307 TPLHCAARNGHVRISEILLDHG-APIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEID 365
Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM----KMTHSELMEKFL 1545
D PLH A H + ++LL GA P +G T + K H +ME L
Sbjct: 366 DITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLL 424
Score = 46.2 bits (108), Expect = 3e-04
Identities = 35/135 (25%), Positives = 63/135 (46%), Gaps = 1/135 (0%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
G T L AA+ G+ E+V L +K + N + +G LH G + + L+++G
Sbjct: 668 GVTPLHLAAQEGHAEMVALLL-SKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVM 726
Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDY 1548
V+ + + G PLH A ++++V+ LL + AD T G + + + +T
Sbjct: 727 VDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLL 786
Query: 1549 LNDLQGRNDDDASGT 1563
L + N+ + GT
Sbjct: 787 LKNGASPNEVSSDGT 801
Score = 42.7 bits (99), Expect = 0.003
Identities = 34/109 (31%), Positives = 49/109 (44%), Gaps = 1/109 (0%)
Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
T RAAR G + L L N + D+N + G LH A G + +V LL +
Sbjct: 47 TSFLRAARSGNLDKALDHLRNGV-DINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILE 105
Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSE 1539
+ + G LH A E+VR L++YGA+ + G T + M E
Sbjct: 106 TTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQE 154
Score = 40.8 bits (94), Expect = 0.011
Identities = 42/163 (25%), Positives = 65/163 (39%), Gaps = 33/163 (20%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGA- 1487
G T L AA+ + EVV + LEN + N G+ L A +G N+V HL+ YG
Sbjct: 144 GFTPLYMAAQENHLEVVKFLLENG-ANQNVATEDGFTPLAVALQQGHENVVAHLINYGTK 202
Query: 1488 ---------------DVNCSA-------------QDGTRPLHDAVENDHLEIVRLLLSYG 1519
D +A + G PLH A ++L + +LLL+ G
Sbjct: 203 GKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRG 262
Query: 1520 ADPTLATYSGRT---IMKMTHSELMEKFLTDYLNDLQGRNDDD 1559
A +G T I + +M + L D ++ + D+
Sbjct: 263 ASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDE 305
>gi|70780359 ankyrin 1 isoform 1 [Homo sapiens]
Length = 1881
Score = 65.1 bits (157), Expect = 6e-10
Identities = 39/118 (33%), Positives = 63/118 (53%), Gaps = 1/118 (0%)
Query: 1433 LQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCS 1492
L A++ G+ ++V+ L +I + G ALH A G +VR L+ YGA+VN
Sbjct: 49 LHLASKEGHVKMVVELLHKEII-LETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQ 107
Query: 1493 AQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLN 1550
+Q G PL+ A + +HLE+V+ LL GA+ +AT G T + + + E + +N
Sbjct: 108 SQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLIN 165
Score = 61.2 bits (147), Expect = 8e-09
Identities = 39/104 (37%), Positives = 54/104 (51%), Gaps = 1/104 (0%)
Query: 1428 AGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGA 1487
AG T L AAR G+ E VL LE + G+ LH A G + + LLE A
Sbjct: 502 AGHTPLHIAAREGHVETVLALLEKEASQAC-MTKKGFTPLHVAAKYGKVRVAELLLERDA 560
Query: 1488 DVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
N + ++G PLH AV +++L+IV+LLL G P ++G T
Sbjct: 561 HPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYT 604
Score = 58.5 bits (140), Expect = 5e-08
Identities = 36/108 (33%), Positives = 54/108 (50%), Gaps = 1/108 (0%)
Query: 1424 VNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLL 1483
+ +G T L A+ G+ V +++ + V+ GY LH A G + +V+ LL
Sbjct: 663 LGNKSGLTPLHLVAQEGHVPVADVLIKHGVM-VDATTRMGYTPLHVASHYGNIKLVKFLL 721
Query: 1484 EYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
++ ADVN + G PLH A + H +IV LLL GA P + G T
Sbjct: 722 QHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTT 769
Score = 57.8 bits (138), Expect = 9e-08
Identities = 40/102 (39%), Positives = 48/102 (47%), Gaps = 1/102 (0%)
Query: 1430 ETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADV 1489
ET L AAR G+ EV Y L+NK VN + LH A G N+V+ LLE A+
Sbjct: 438 ETPLHMAARAGHTEVAKYLLQNK-AKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANP 496
Query: 1490 NCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
N + G PLH A H+E V LL A T G T
Sbjct: 497 NLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFT 538
Score = 55.5 bits (132), Expect = 5e-07
Identities = 34/91 (37%), Positives = 49/91 (53%), Gaps = 1/91 (1%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
G T L AA G +EVV L N +VN + G+ L+ A L +V+ LLE GA+
Sbjct: 78 GNTALHIAALAGQDEVVRE-LVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGAN 136
Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYG 1519
N + +DG PL A++ H +V L++YG
Sbjct: 137 QNVATEDGFTPLAVALQQGHENVVAHLINYG 167
Score = 55.5 bits (132), Expect = 5e-07
Identities = 29/77 (37%), Positives = 39/77 (50%)
Query: 1463 GYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADP 1522
GY LH A + + + R LL+YG N + G PLH A + H E+V LLLS A+
Sbjct: 602 GYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANG 661
Query: 1523 TLATYSGRTIMKMTHSE 1539
L SG T + + E
Sbjct: 662 NLGNKSGLTPLHLVAQE 678
Score = 54.7 bits (130), Expect = 8e-07
Identities = 41/133 (30%), Positives = 61/133 (45%), Gaps = 6/133 (4%)
Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
T L AA G+ V L+ K N R G+ LH AC + + ++ LL+ GA ++
Sbjct: 340 TPLHVAAHCGHHRVAKVLLD-KGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASID 398
Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMT----HSELMEKFLT 1546
+ G PLH A HL IV+ LL GA P ++ T + M H+E + K+L
Sbjct: 399 AVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTE-VAKYLL 457
Query: 1547 DYLNDLQGRNDDD 1559
+ + DD
Sbjct: 458 QNKAKVNAKAKDD 470
Score = 54.3 bits (129), Expect = 1e-06
Identities = 44/140 (31%), Positives = 61/140 (43%), Gaps = 9/140 (6%)
Query: 1430 ETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADV 1489
+T L AAR+G+ +V LEN + N AG+ LH A G + V LLE A
Sbjct: 471 QTPLHCAARIGHTNMVKLLLENN-ANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQ 529
Query: 1490 NCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMT--HSELMEKFLTD 1547
C + G PLH A + + + LLL A P A +G T + + H+ L D
Sbjct: 530 ACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNL------D 583
Query: 1548 YLNDLQGRNDDDASGTWDFY 1567
+ L R S W+ Y
Sbjct: 584 IVKLLLPRGGSPHSPAWNGY 603
Score = 52.8 bits (125), Expect = 3e-06
Identities = 40/113 (35%), Positives = 53/113 (46%), Gaps = 3/113 (2%)
Query: 1424 VNKNAGETLLQRAARLGYEEV-VLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHL 1482
V G T L AA YE + V L N+ VN G LH A RG + +VR L
Sbjct: 201 VLSKTGFTPLHIAAH--YENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLL 258
Query: 1483 LEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKM 1535
L+ GA + +D PLH A N H+ I +LL +GA T +G + + M
Sbjct: 259 LDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHM 311
Score = 52.8 bits (125), Expect = 3e-06
Identities = 28/73 (38%), Positives = 39/73 (53%)
Query: 1467 LHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLAT 1526
LH A G + ++LL+ A VN A+D PLH A H +V+LLL A+P LAT
Sbjct: 441 LHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLAT 500
Query: 1527 YSGRTIMKMTHSE 1539
+G T + + E
Sbjct: 501 TAGHTPLHIAARE 513
Score = 51.2 bits (121), Expect = 8e-06
Identities = 33/109 (30%), Positives = 55/109 (50%), Gaps = 9/109 (8%)
Query: 1421 RLIVNKNA--------GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACA 1472
+L++N+ A G T L A+R G +++ L ++ + + LH A
Sbjct: 223 QLLLNRGASVNFTPQNGITPLHIASRRG-NVIMVRLLLDRGAQIETKTKDELTPLHCAAR 281
Query: 1473 RGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGAD 1521
G + I LL++GA + ++G P+H A + DHL+ VRLLL Y A+
Sbjct: 282 NGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAE 330
Score = 48.1 bits (113), Expect = 7e-05
Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 6/137 (4%)
Query: 1418 EARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLN 1477
EA + + K G T L AA+ G V LE N G LH A L+
Sbjct: 526 EASQACMTKK-GFTPLHVAAKYGKVRVAELLLERD-AHPNAAGKNGLTPLHVAVHHNNLD 583
Query: 1478 IVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMT- 1536
IV+ LL G + A +G PLH A + + +E+ R LL YG + G T + +
Sbjct: 584 IVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAA 643
Query: 1537 ---HSELMEKFLTDYLN 1550
H+E++ L+ N
Sbjct: 644 QEGHAEMVALLLSKQAN 660
Score = 47.4 bits (111), Expect = 1e-04
Identities = 30/87 (34%), Positives = 47/87 (54%), Gaps = 1/87 (1%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
G T L A+ G ++V + L+++ DVN + GY LH+A +G +IV LL+ GA
Sbjct: 701 GYTPLHVASHYGNIKLVKFLLQHQ-ADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGAS 759
Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLL 1515
N + DGT PL A ++ + +L
Sbjct: 760 PNEVSSDGTTPLAIAKRLGYISVTDVL 786
Score = 46.2 bits (108), Expect = 3e-04
Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 5/119 (4%)
Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
T L AAR G+ + L++ + + G +H A L+ VR LL+Y A+++
Sbjct: 274 TPLHCAARNGHVRISEILLDHG-APIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEID 332
Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM----KMTHSELMEKFL 1545
D PLH A H + ++LL GA P +G T + K H +ME L
Sbjct: 333 DITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLL 391
Score = 46.2 bits (108), Expect = 3e-04
Identities = 35/135 (25%), Positives = 63/135 (46%), Gaps = 1/135 (0%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
G T L AA+ G+ E+V L +K + N + +G LH G + + L+++G
Sbjct: 635 GVTPLHLAAQEGHAEMVALLL-SKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVM 693
Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDY 1548
V+ + + G PLH A ++++V+ LL + AD T G + + + +T
Sbjct: 694 VDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLL 753
Query: 1549 LNDLQGRNDDDASGT 1563
L + N+ + GT
Sbjct: 754 LKNGASPNEVSSDGT 768
Score = 42.7 bits (99), Expect = 0.003
Identities = 34/109 (31%), Positives = 49/109 (44%), Gaps = 1/109 (0%)
Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
T RAAR G + L L N + D+N + G LH A G + +V LL +
Sbjct: 14 TSFLRAARSGNLDKALDHLRNGV-DINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILE 72
Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSE 1539
+ + G LH A E+VR L++YGA+ + G T + M E
Sbjct: 73 TTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQE 121
Score = 40.8 bits (94), Expect = 0.011
Identities = 42/163 (25%), Positives = 65/163 (39%), Gaps = 33/163 (20%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGA- 1487
G T L AA+ + EVV + LEN + N G+ L A +G N+V HL+ YG
Sbjct: 111 GFTPLYMAAQENHLEVVKFLLENG-ANQNVATEDGFTPLAVALQQGHENVVAHLINYGTK 169
Query: 1488 ---------------DVNCSA-------------QDGTRPLHDAVENDHLEIVRLLLSYG 1519
D +A + G PLH A ++L + +LLL+ G
Sbjct: 170 GKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRG 229
Query: 1520 ADPTLATYSGRT---IMKMTHSELMEKFLTDYLNDLQGRNDDD 1559
A +G T I + +M + L D ++ + D+
Sbjct: 230 ASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDE 272
>gi|70780357 ankyrin 1 isoform 3 [Homo sapiens]
Length = 1880
Score = 65.1 bits (157), Expect = 6e-10
Identities = 39/118 (33%), Positives = 63/118 (53%), Gaps = 1/118 (0%)
Query: 1433 LQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCS 1492
L A++ G+ ++V+ L +I + G ALH A G +VR L+ YGA+VN
Sbjct: 49 LHLASKEGHVKMVVELLHKEII-LETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQ 107
Query: 1493 AQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLN 1550
+Q G PL+ A + +HLE+V+ LL GA+ +AT G T + + + E + +N
Sbjct: 108 SQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLIN 165
Score = 61.2 bits (147), Expect = 8e-09
Identities = 39/104 (37%), Positives = 54/104 (51%), Gaps = 1/104 (0%)
Query: 1428 AGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGA 1487
AG T L AAR G+ E VL LE + G+ LH A G + + LLE A
Sbjct: 502 AGHTPLHIAAREGHVETVLALLEKEASQAC-MTKKGFTPLHVAAKYGKVRVAELLLERDA 560
Query: 1488 DVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
N + ++G PLH AV +++L+IV+LLL G P ++G T
Sbjct: 561 HPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYT 604
Score = 58.5 bits (140), Expect = 5e-08
Identities = 36/108 (33%), Positives = 54/108 (50%), Gaps = 1/108 (0%)
Query: 1424 VNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLL 1483
+ +G T L A+ G+ V +++ + V+ GY LH A G + +V+ LL
Sbjct: 663 LGNKSGLTPLHLVAQEGHVPVADVLIKHGVM-VDATTRMGYTPLHVASHYGNIKLVKFLL 721
Query: 1484 EYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
++ ADVN + G PLH A + H +IV LLL GA P + G T
Sbjct: 722 QHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTT 769
Score = 57.8 bits (138), Expect = 9e-08
Identities = 40/102 (39%), Positives = 48/102 (47%), Gaps = 1/102 (0%)
Query: 1430 ETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADV 1489
ET L AAR G+ EV Y L+NK VN + LH A G N+V+ LLE A+
Sbjct: 438 ETPLHMAARAGHTEVAKYLLQNK-AKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANP 496
Query: 1490 NCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
N + G PLH A H+E V LL A T G T
Sbjct: 497 NLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFT 538
Score = 55.5 bits (132), Expect = 5e-07
Identities = 34/91 (37%), Positives = 49/91 (53%), Gaps = 1/91 (1%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
G T L AA G +EVV L N +VN + G+ L+ A L +V+ LLE GA+
Sbjct: 78 GNTALHIAALAGQDEVVRE-LVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGAN 136
Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYG 1519
N + +DG PL A++ H +V L++YG
Sbjct: 137 QNVATEDGFTPLAVALQQGHENVVAHLINYG 167
Score = 55.5 bits (132), Expect = 5e-07
Identities = 29/77 (37%), Positives = 39/77 (50%)
Query: 1463 GYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADP 1522
GY LH A + + + R LL+YG N + G PLH A + H E+V LLLS A+
Sbjct: 602 GYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANG 661
Query: 1523 TLATYSGRTIMKMTHSE 1539
L SG T + + E
Sbjct: 662 NLGNKSGLTPLHLVAQE 678
Score = 54.7 bits (130), Expect = 8e-07
Identities = 41/133 (30%), Positives = 61/133 (45%), Gaps = 6/133 (4%)
Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
T L AA G+ V L+ K N R G+ LH AC + + ++ LL+ GA ++
Sbjct: 340 TPLHVAAHCGHHRVAKVLLD-KGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASID 398
Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMT----HSELMEKFLT 1546
+ G PLH A HL IV+ LL GA P ++ T + M H+E + K+L
Sbjct: 399 AVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTE-VAKYLL 457
Query: 1547 DYLNDLQGRNDDD 1559
+ + DD
Sbjct: 458 QNKAKVNAKAKDD 470
Score = 54.3 bits (129), Expect = 1e-06
Identities = 44/140 (31%), Positives = 61/140 (43%), Gaps = 9/140 (6%)
Query: 1430 ETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADV 1489
+T L AAR+G+ +V LEN + N AG+ LH A G + V LLE A
Sbjct: 471 QTPLHCAARIGHTNMVKLLLENN-ANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQ 529
Query: 1490 NCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMT--HSELMEKFLTD 1547
C + G PLH A + + + LLL A P A +G T + + H+ L D
Sbjct: 530 ACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNL------D 583
Query: 1548 YLNDLQGRNDDDASGTWDFY 1567
+ L R S W+ Y
Sbjct: 584 IVKLLLPRGGSPHSPAWNGY 603
Score = 52.8 bits (125), Expect = 3e-06
Identities = 40/113 (35%), Positives = 53/113 (46%), Gaps = 3/113 (2%)
Query: 1424 VNKNAGETLLQRAARLGYEEV-VLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHL 1482
V G T L AA YE + V L N+ VN G LH A RG + +VR L
Sbjct: 201 VLSKTGFTPLHIAAH--YENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLL 258
Query: 1483 LEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKM 1535
L+ GA + +D PLH A N H+ I +LL +GA T +G + + M
Sbjct: 259 LDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHM 311
Score = 52.8 bits (125), Expect = 3e-06
Identities = 28/73 (38%), Positives = 39/73 (53%)
Query: 1467 LHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLAT 1526
LH A G + ++LL+ A VN A+D PLH A H +V+LLL A+P LAT
Sbjct: 441 LHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLAT 500
Query: 1527 YSGRTIMKMTHSE 1539
+G T + + E
Sbjct: 501 TAGHTPLHIAARE 513
Score = 51.2 bits (121), Expect = 8e-06
Identities = 33/109 (30%), Positives = 55/109 (50%), Gaps = 9/109 (8%)
Query: 1421 RLIVNKNA--------GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACA 1472
+L++N+ A G T L A+R G +++ L ++ + + LH A
Sbjct: 223 QLLLNRGASVNFTPQNGITPLHIASRRG-NVIMVRLLLDRGAQIETKTKDELTPLHCAAR 281
Query: 1473 RGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGAD 1521
G + I LL++GA + ++G P+H A + DHL+ VRLLL Y A+
Sbjct: 282 NGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAE 330
Score = 48.1 bits (113), Expect = 7e-05
Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 6/137 (4%)
Query: 1418 EARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLN 1477
EA + + K G T L AA+ G V LE N G LH A L+
Sbjct: 526 EASQACMTKK-GFTPLHVAAKYGKVRVAELLLERD-AHPNAAGKNGLTPLHVAVHHNNLD 583
Query: 1478 IVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMT- 1536
IV+ LL G + A +G PLH A + + +E+ R LL YG + G T + +
Sbjct: 584 IVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAA 643
Query: 1537 ---HSELMEKFLTDYLN 1550
H+E++ L+ N
Sbjct: 644 QEGHAEMVALLLSKQAN 660
Score = 47.4 bits (111), Expect = 1e-04
Identities = 30/87 (34%), Positives = 47/87 (54%), Gaps = 1/87 (1%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
G T L A+ G ++V + L+++ DVN + GY LH+A +G +IV LL+ GA
Sbjct: 701 GYTPLHVASHYGNIKLVKFLLQHQ-ADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGAS 759
Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLL 1515
N + DGT PL A ++ + +L
Sbjct: 760 PNEVSSDGTTPLAIAKRLGYISVTDVL 786
Score = 46.2 bits (108), Expect = 3e-04
Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 5/119 (4%)
Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
T L AAR G+ + L++ + + G +H A L+ VR LL+Y A+++
Sbjct: 274 TPLHCAARNGHVRISEILLDHG-APIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEID 332
Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM----KMTHSELMEKFL 1545
D PLH A H + ++LL GA P +G T + K H +ME L
Sbjct: 333 DITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLL 391
Score = 46.2 bits (108), Expect = 3e-04
Identities = 35/135 (25%), Positives = 63/135 (46%), Gaps = 1/135 (0%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
G T L AA+ G+ E+V L +K + N + +G LH G + + L+++G
Sbjct: 635 GVTPLHLAAQEGHAEMVALLL-SKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVM 693
Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDY 1548
V+ + + G PLH A ++++V+ LL + AD T G + + + +T
Sbjct: 694 VDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLL 753
Query: 1549 LNDLQGRNDDDASGT 1563
L + N+ + GT
Sbjct: 754 LKNGASPNEVSSDGT 768
Score = 42.7 bits (99), Expect = 0.003
Identities = 34/109 (31%), Positives = 49/109 (44%), Gaps = 1/109 (0%)
Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
T RAAR G + L L N + D+N + G LH A G + +V LL +
Sbjct: 14 TSFLRAARSGNLDKALDHLRNGV-DINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILE 72
Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSE 1539
+ + G LH A E+VR L++YGA+ + G T + M E
Sbjct: 73 TTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQE 121
Score = 40.8 bits (94), Expect = 0.011
Identities = 42/163 (25%), Positives = 65/163 (39%), Gaps = 33/163 (20%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGA- 1487
G T L AA+ + EVV + LEN + N G+ L A +G N+V HL+ YG
Sbjct: 111 GFTPLYMAAQENHLEVVKFLLENG-ANQNVATEDGFTPLAVALQQGHENVVAHLINYGTK 169
Query: 1488 ---------------DVNCSA-------------QDGTRPLHDAVENDHLEIVRLLLSYG 1519
D +A + G PLH A ++L + +LLL+ G
Sbjct: 170 GKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRG 229
Query: 1520 ADPTLATYSGRT---IMKMTHSELMEKFLTDYLNDLQGRNDDD 1559
A +G T I + +M + L D ++ + D+
Sbjct: 230 ASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDE 272
>gi|70780355 ankyrin 1 isoform 2 [Homo sapiens]
Length = 1719
Score = 65.1 bits (157), Expect = 6e-10
Identities = 39/118 (33%), Positives = 63/118 (53%), Gaps = 1/118 (0%)
Query: 1433 LQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCS 1492
L A++ G+ ++V+ L +I + G ALH A G +VR L+ YGA+VN
Sbjct: 49 LHLASKEGHVKMVVELLHKEII-LETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQ 107
Query: 1493 AQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLN 1550
+Q G PL+ A + +HLE+V+ LL GA+ +AT G T + + + E + +N
Sbjct: 108 SQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLIN 165
Score = 61.2 bits (147), Expect = 8e-09
Identities = 39/104 (37%), Positives = 54/104 (51%), Gaps = 1/104 (0%)
Query: 1428 AGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGA 1487
AG T L AAR G+ E VL LE + G+ LH A G + + LLE A
Sbjct: 502 AGHTPLHIAAREGHVETVLALLEKEASQAC-MTKKGFTPLHVAAKYGKVRVAELLLERDA 560
Query: 1488 DVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
N + ++G PLH AV +++L+IV+LLL G P ++G T
Sbjct: 561 HPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYT 604
Score = 58.5 bits (140), Expect = 5e-08
Identities = 36/108 (33%), Positives = 54/108 (50%), Gaps = 1/108 (0%)
Query: 1424 VNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLL 1483
+ +G T L A+ G+ V +++ + V+ GY LH A G + +V+ LL
Sbjct: 663 LGNKSGLTPLHLVAQEGHVPVADVLIKHGVM-VDATTRMGYTPLHVASHYGNIKLVKFLL 721
Query: 1484 EYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
++ ADVN + G PLH A + H +IV LLL GA P + G T
Sbjct: 722 QHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTT 769
Score = 57.8 bits (138), Expect = 9e-08
Identities = 40/102 (39%), Positives = 48/102 (47%), Gaps = 1/102 (0%)
Query: 1430 ETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADV 1489
ET L AAR G+ EV Y L+NK VN + LH A G N+V+ LLE A+
Sbjct: 438 ETPLHMAARAGHTEVAKYLLQNK-AKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANP 496
Query: 1490 NCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
N + G PLH A H+E V LL A T G T
Sbjct: 497 NLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFT 538
Score = 55.5 bits (132), Expect = 5e-07
Identities = 34/91 (37%), Positives = 49/91 (53%), Gaps = 1/91 (1%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
G T L AA G +EVV L N +VN + G+ L+ A L +V+ LLE GA+
Sbjct: 78 GNTALHIAALAGQDEVVRE-LVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGAN 136
Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYG 1519
N + +DG PL A++ H +V L++YG
Sbjct: 137 QNVATEDGFTPLAVALQQGHENVVAHLINYG 167
Score = 55.5 bits (132), Expect = 5e-07
Identities = 29/77 (37%), Positives = 39/77 (50%)
Query: 1463 GYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADP 1522
GY LH A + + + R LL+YG N + G PLH A + H E+V LLLS A+
Sbjct: 602 GYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANG 661
Query: 1523 TLATYSGRTIMKMTHSE 1539
L SG T + + E
Sbjct: 662 NLGNKSGLTPLHLVAQE 678
Score = 54.7 bits (130), Expect = 8e-07
Identities = 41/133 (30%), Positives = 61/133 (45%), Gaps = 6/133 (4%)
Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
T L AA G+ V L+ K N R G+ LH AC + + ++ LL+ GA ++
Sbjct: 340 TPLHVAAHCGHHRVAKVLLD-KGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASID 398
Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMT----HSELMEKFLT 1546
+ G PLH A HL IV+ LL GA P ++ T + M H+E + K+L
Sbjct: 399 AVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTE-VAKYLL 457
Query: 1547 DYLNDLQGRNDDD 1559
+ + DD
Sbjct: 458 QNKAKVNAKAKDD 470
Score = 54.3 bits (129), Expect = 1e-06
Identities = 44/140 (31%), Positives = 61/140 (43%), Gaps = 9/140 (6%)
Query: 1430 ETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADV 1489
+T L AAR+G+ +V LEN + N AG+ LH A G + V LLE A
Sbjct: 471 QTPLHCAARIGHTNMVKLLLENN-ANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQ 529
Query: 1490 NCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMT--HSELMEKFLTD 1547
C + G PLH A + + + LLL A P A +G T + + H+ L D
Sbjct: 530 ACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNL------D 583
Query: 1548 YLNDLQGRNDDDASGTWDFY 1567
+ L R S W+ Y
Sbjct: 584 IVKLLLPRGGSPHSPAWNGY 603
Score = 52.8 bits (125), Expect = 3e-06
Identities = 40/113 (35%), Positives = 53/113 (46%), Gaps = 3/113 (2%)
Query: 1424 VNKNAGETLLQRAARLGYEEV-VLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHL 1482
V G T L AA YE + V L N+ VN G LH A RG + +VR L
Sbjct: 201 VLSKTGFTPLHIAAH--YENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLL 258
Query: 1483 LEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKM 1535
L+ GA + +D PLH A N H+ I +LL +GA T +G + + M
Sbjct: 259 LDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHM 311
Score = 52.8 bits (125), Expect = 3e-06
Identities = 28/73 (38%), Positives = 39/73 (53%)
Query: 1467 LHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLAT 1526
LH A G + ++LL+ A VN A+D PLH A H +V+LLL A+P LAT
Sbjct: 441 LHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLAT 500
Query: 1527 YSGRTIMKMTHSE 1539
+G T + + E
Sbjct: 501 TAGHTPLHIAARE 513
Score = 51.2 bits (121), Expect = 8e-06
Identities = 33/109 (30%), Positives = 55/109 (50%), Gaps = 9/109 (8%)
Query: 1421 RLIVNKNA--------GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACA 1472
+L++N+ A G T L A+R G +++ L ++ + + LH A
Sbjct: 223 QLLLNRGASVNFTPQNGITPLHIASRRG-NVIMVRLLLDRGAQIETKTKDELTPLHCAAR 281
Query: 1473 RGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGAD 1521
G + I LL++GA + ++G P+H A + DHL+ VRLLL Y A+
Sbjct: 282 NGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAE 330
Score = 48.1 bits (113), Expect = 7e-05
Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 6/137 (4%)
Query: 1418 EARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLN 1477
EA + + K G T L AA+ G V LE N G LH A L+
Sbjct: 526 EASQACMTKK-GFTPLHVAAKYGKVRVAELLLERD-AHPNAAGKNGLTPLHVAVHHNNLD 583
Query: 1478 IVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMT- 1536
IV+ LL G + A +G PLH A + + +E+ R LL YG + G T + +
Sbjct: 584 IVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAA 643
Query: 1537 ---HSELMEKFLTDYLN 1550
H+E++ L+ N
Sbjct: 644 QEGHAEMVALLLSKQAN 660
Score = 47.4 bits (111), Expect = 1e-04
Identities = 30/87 (34%), Positives = 47/87 (54%), Gaps = 1/87 (1%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
G T L A+ G ++V + L+++ DVN + GY LH+A +G +IV LL+ GA
Sbjct: 701 GYTPLHVASHYGNIKLVKFLLQHQ-ADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGAS 759
Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLL 1515
N + DGT PL A ++ + +L
Sbjct: 760 PNEVSSDGTTPLAIAKRLGYISVTDVL 786
Score = 46.2 bits (108), Expect = 3e-04
Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 5/119 (4%)
Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
T L AAR G+ + L++ + + G +H A L+ VR LL+Y A+++
Sbjct: 274 TPLHCAARNGHVRISEILLDHG-APIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEID 332
Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM----KMTHSELMEKFL 1545
D PLH A H + ++LL GA P +G T + K H +ME L
Sbjct: 333 DITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLL 391
Score = 46.2 bits (108), Expect = 3e-04
Identities = 35/135 (25%), Positives = 63/135 (46%), Gaps = 1/135 (0%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
G T L AA+ G+ E+V L +K + N + +G LH G + + L+++G
Sbjct: 635 GVTPLHLAAQEGHAEMVALLL-SKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVM 693
Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDY 1548
V+ + + G PLH A ++++V+ LL + AD T G + + + +T
Sbjct: 694 VDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLL 753
Query: 1549 LNDLQGRNDDDASGT 1563
L + N+ + GT
Sbjct: 754 LKNGASPNEVSSDGT 768
Score = 42.7 bits (99), Expect = 0.003
Identities = 34/109 (31%), Positives = 49/109 (44%), Gaps = 1/109 (0%)
Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
T RAAR G + L L N + D+N + G LH A G + +V LL +
Sbjct: 14 TSFLRAARSGNLDKALDHLRNGV-DINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILE 72
Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSE 1539
+ + G LH A E+VR L++YGA+ + G T + M E
Sbjct: 73 TTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQE 121
Score = 40.8 bits (94), Expect = 0.011
Identities = 42/163 (25%), Positives = 65/163 (39%), Gaps = 33/163 (20%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGA- 1487
G T L AA+ + EVV + LEN + N G+ L A +G N+V HL+ YG
Sbjct: 111 GFTPLYMAAQENHLEVVKFLLENG-ANQNVATEDGFTPLAVALQQGHENVVAHLINYGTK 169
Query: 1488 ---------------DVNCSA-------------QDGTRPLHDAVENDHLEIVRLLLSYG 1519
D +A + G PLH A ++L + +LLL+ G
Sbjct: 170 GKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRG 229
Query: 1520 ADPTLATYSGRT---IMKMTHSELMEKFLTDYLNDLQGRNDDD 1559
A +G T I + +M + L D ++ + D+
Sbjct: 230 ASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDE 272
>gi|70780353 ankyrin 1 isoform 4 [Homo sapiens]
Length = 1856
Score = 65.1 bits (157), Expect = 6e-10
Identities = 39/118 (33%), Positives = 63/118 (53%), Gaps = 1/118 (0%)
Query: 1433 LQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCS 1492
L A++ G+ ++V+ L +I + G ALH A G +VR L+ YGA+VN
Sbjct: 49 LHLASKEGHVKMVVELLHKEII-LETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQ 107
Query: 1493 AQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLN 1550
+Q G PL+ A + +HLE+V+ LL GA+ +AT G T + + + E + +N
Sbjct: 108 SQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLIN 165
Score = 61.2 bits (147), Expect = 8e-09
Identities = 39/104 (37%), Positives = 54/104 (51%), Gaps = 1/104 (0%)
Query: 1428 AGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGA 1487
AG T L AAR G+ E VL LE + G+ LH A G + + LLE A
Sbjct: 502 AGHTPLHIAAREGHVETVLALLEKEASQAC-MTKKGFTPLHVAAKYGKVRVAELLLERDA 560
Query: 1488 DVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
N + ++G PLH AV +++L+IV+LLL G P ++G T
Sbjct: 561 HPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYT 604
Score = 58.5 bits (140), Expect = 5e-08
Identities = 36/108 (33%), Positives = 54/108 (50%), Gaps = 1/108 (0%)
Query: 1424 VNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLL 1483
+ +G T L A+ G+ V +++ + V+ GY LH A G + +V+ LL
Sbjct: 663 LGNKSGLTPLHLVAQEGHVPVADVLIKHGVM-VDATTRMGYTPLHVASHYGNIKLVKFLL 721
Query: 1484 EYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
++ ADVN + G PLH A + H +IV LLL GA P + G T
Sbjct: 722 QHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTT 769
Score = 57.8 bits (138), Expect = 9e-08
Identities = 40/102 (39%), Positives = 48/102 (47%), Gaps = 1/102 (0%)
Query: 1430 ETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADV 1489
ET L AAR G+ EV Y L+NK VN + LH A G N+V+ LLE A+
Sbjct: 438 ETPLHMAARAGHTEVAKYLLQNK-AKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANP 496
Query: 1490 NCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRT 1531
N + G PLH A H+E V LL A T G T
Sbjct: 497 NLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFT 538
Score = 55.5 bits (132), Expect = 5e-07
Identities = 34/91 (37%), Positives = 49/91 (53%), Gaps = 1/91 (1%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
G T L AA G +EVV L N +VN + G+ L+ A L +V+ LLE GA+
Sbjct: 78 GNTALHIAALAGQDEVVRE-LVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGAN 136
Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYG 1519
N + +DG PL A++ H +V L++YG
Sbjct: 137 QNVATEDGFTPLAVALQQGHENVVAHLINYG 167
Score = 55.5 bits (132), Expect = 5e-07
Identities = 29/77 (37%), Positives = 39/77 (50%)
Query: 1463 GYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADP 1522
GY LH A + + + R LL+YG N + G PLH A + H E+V LLLS A+
Sbjct: 602 GYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANG 661
Query: 1523 TLATYSGRTIMKMTHSE 1539
L SG T + + E
Sbjct: 662 NLGNKSGLTPLHLVAQE 678
Score = 54.7 bits (130), Expect = 8e-07
Identities = 41/133 (30%), Positives = 61/133 (45%), Gaps = 6/133 (4%)
Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
T L AA G+ V L+ K N R G+ LH AC + + ++ LL+ GA ++
Sbjct: 340 TPLHVAAHCGHHRVAKVLLD-KGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASID 398
Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMT----HSELMEKFLT 1546
+ G PLH A HL IV+ LL GA P ++ T + M H+E + K+L
Sbjct: 399 AVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTE-VAKYLL 457
Query: 1547 DYLNDLQGRNDDD 1559
+ + DD
Sbjct: 458 QNKAKVNAKAKDD 470
Score = 54.3 bits (129), Expect = 1e-06
Identities = 44/140 (31%), Positives = 61/140 (43%), Gaps = 9/140 (6%)
Query: 1430 ETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADV 1489
+T L AAR+G+ +V LEN + N AG+ LH A G + V LLE A
Sbjct: 471 QTPLHCAARIGHTNMVKLLLENN-ANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQ 529
Query: 1490 NCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMT--HSELMEKFLTD 1547
C + G PLH A + + + LLL A P A +G T + + H+ L D
Sbjct: 530 ACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNL------D 583
Query: 1548 YLNDLQGRNDDDASGTWDFY 1567
+ L R S W+ Y
Sbjct: 584 IVKLLLPRGGSPHSPAWNGY 603
Score = 52.8 bits (125), Expect = 3e-06
Identities = 40/113 (35%), Positives = 53/113 (46%), Gaps = 3/113 (2%)
Query: 1424 VNKNAGETLLQRAARLGYEEV-VLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHL 1482
V G T L AA YE + V L N+ VN G LH A RG + +VR L
Sbjct: 201 VLSKTGFTPLHIAAH--YENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLL 258
Query: 1483 LEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKM 1535
L+ GA + +D PLH A N H+ I +LL +GA T +G + + M
Sbjct: 259 LDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHM 311
Score = 52.8 bits (125), Expect = 3e-06
Identities = 28/73 (38%), Positives = 39/73 (53%)
Query: 1467 LHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLAT 1526
LH A G + ++LL+ A VN A+D PLH A H +V+LLL A+P LAT
Sbjct: 441 LHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLAT 500
Query: 1527 YSGRTIMKMTHSE 1539
+G T + + E
Sbjct: 501 TAGHTPLHIAARE 513
Score = 51.2 bits (121), Expect = 8e-06
Identities = 33/109 (30%), Positives = 55/109 (50%), Gaps = 9/109 (8%)
Query: 1421 RLIVNKNA--------GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACA 1472
+L++N+ A G T L A+R G +++ L ++ + + LH A
Sbjct: 223 QLLLNRGASVNFTPQNGITPLHIASRRG-NVIMVRLLLDRGAQIETKTKDELTPLHCAAR 281
Query: 1473 RGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGAD 1521
G + I LL++GA + ++G P+H A + DHL+ VRLLL Y A+
Sbjct: 282 NGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAE 330
Score = 48.1 bits (113), Expect = 7e-05
Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 6/137 (4%)
Query: 1418 EARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLN 1477
EA + + K G T L AA+ G V LE N G LH A L+
Sbjct: 526 EASQACMTKK-GFTPLHVAAKYGKVRVAELLLERD-AHPNAAGKNGLTPLHVAVHHNNLD 583
Query: 1478 IVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMT- 1536
IV+ LL G + A +G PLH A + + +E+ R LL YG + G T + +
Sbjct: 584 IVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAA 643
Query: 1537 ---HSELMEKFLTDYLN 1550
H+E++ L+ N
Sbjct: 644 QEGHAEMVALLLSKQAN 660
Score = 47.4 bits (111), Expect = 1e-04
Identities = 30/87 (34%), Positives = 47/87 (54%), Gaps = 1/87 (1%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
G T L A+ G ++V + L+++ DVN + GY LH+A +G +IV LL+ GA
Sbjct: 701 GYTPLHVASHYGNIKLVKFLLQHQ-ADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGAS 759
Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLL 1515
N + DGT PL A ++ + +L
Sbjct: 760 PNEVSSDGTTPLAIAKRLGYISVTDVL 786
Score = 46.2 bits (108), Expect = 3e-04
Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 5/119 (4%)
Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
T L AAR G+ + L++ + + G +H A L+ VR LL+Y A+++
Sbjct: 274 TPLHCAARNGHVRISEILLDHG-APIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEID 332
Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIM----KMTHSELMEKFL 1545
D PLH A H + ++LL GA P +G T + K H +ME L
Sbjct: 333 DITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLL 391
Score = 46.2 bits (108), Expect = 3e-04
Identities = 35/135 (25%), Positives = 63/135 (46%), Gaps = 1/135 (0%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGAD 1488
G T L AA+ G+ E+V L +K + N + +G LH G + + L+++G
Sbjct: 635 GVTPLHLAAQEGHAEMVALLL-SKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVM 693
Query: 1489 VNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDY 1548
V+ + + G PLH A ++++V+ LL + AD T G + + + +T
Sbjct: 694 VDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLL 753
Query: 1549 LNDLQGRNDDDASGT 1563
L + N+ + GT
Sbjct: 754 LKNGASPNEVSSDGT 768
Score = 42.7 bits (99), Expect = 0.003
Identities = 34/109 (31%), Positives = 49/109 (44%), Gaps = 1/109 (0%)
Query: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490
T RAAR G + L L N + D+N + G LH A G + +V LL +
Sbjct: 14 TSFLRAARSGNLDKALDHLRNGV-DINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILE 72
Query: 1491 CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSE 1539
+ + G LH A E+VR L++YGA+ + G T + M E
Sbjct: 73 TTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQE 121
Score = 40.8 bits (94), Expect = 0.011
Identities = 42/163 (25%), Positives = 65/163 (39%), Gaps = 33/163 (20%)
Query: 1429 GETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGA- 1487
G T L AA+ + EVV + LEN + N G+ L A +G N+V HL+ YG
Sbjct: 111 GFTPLYMAAQENHLEVVKFLLENG-ANQNVATEDGFTPLAVALQQGHENVVAHLINYGTK 169
Query: 1488 ---------------DVNCSA-------------QDGTRPLHDAVENDHLEIVRLLLSYG 1519
D +A + G PLH A ++L + +LLL+ G
Sbjct: 170 GKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRG 229
Query: 1520 ADPTLATYSGRT---IMKMTHSELMEKFLTDYLNDLQGRNDDD 1559
A +G T I + +M + L D ++ + D+
Sbjct: 230 ASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDE 272
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.129 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 80,051,309
Number of Sequences: 37866
Number of extensions: 4577666
Number of successful extensions: 19742
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 324
Number of HSP's successfully gapped in prelim test: 697
Number of HSP's that attempted gapping in prelim test: 15262
Number of HSP's gapped (non-prelim): 4675
length of query: 1721
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1605
effective length of database: 13,855,062
effective search space: 22237374510
effective search space used: 22237374510
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.