Search of human proteins with 18254460

Search of human proteins with 18254460

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|18254460 splA/ryanodine receptor domain and SOCS box
containing 4 [Homo sapiens]
         (273 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|18254460 splA/ryanodine receptor domain and SOCS box containi...   560   e-160
gi|18141316 splA/ryanodine receptor domain and SOCS box containi...   434   e-122
gi|226423903 splA/ryanodine receptor domain and SOCS box contain...   267   6e-72
gi|14249178 splA/ryanodine receptor domain and SOCS box containi...   267   6e-72
gi|226423905 splA/ryanodine receptor domain and SOCS box contain...   233   1e-61
gi|157743247 F-box protein 45 [Homo sapiens]                          151   7e-37
gi|27552770 splA/ryanodine receptor domain and SOCS box containi...    62   7e-10
gi|18252778 ankyrin repeat and SOCS box-containing protein 2 [Ho...    42   4e-04
gi|38176283 ankyrin repeat and SOCS box-containing protein 7 iso...    42   8e-04
gi|18254476 ankyrin repeat and SOCS box-containing protein 5 [Ho...    42   8e-04
gi|94721248 ankyrin repeat and SOCS box-containing protein 1 [Ho...    41   0.001
gi|126131099 guanine nucleotide exchange factor p532 [Homo sapiens]    41   0.001
gi|22208951 ankyrin repeat and SOCS box-containing protein 3 iso...    40   0.002
gi|7705831 ankyrin repeat and SOCS box-containing protein 3 isof...    40   0.002
gi|134288906 tripartite motif-containing 67 [Homo sapiens]             39   0.004
gi|37588869 ring finger protein 123 [Homo sapiens]                     39   0.006
gi|190341104 tripartite motif protein 9 isoform 1 [Homo sapiens]       39   0.006
gi|4826686 DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 [Homo sapiens]     35   0.054
gi|22208957 ankyrin repeat and SOCS box-containing protein 13 [H...    35   0.054
gi|18254474 ankyrin repeat and SOCS box-containing protein 11 is...    35   0.070
gi|60218887 ankyrin repeat and SOCS box-containing protein 11 is...    35   0.070
gi|72534772 ankyrin repeat and SOCS box-containing 9 isoform 1 [...    34   0.12 
gi|154354992 B-box and SPRY domain containing [Homo sapiens]           34   0.12 
gi|13129098 ankyrin repeat and SOCS box-containing 8 [Homo sapiens]    34   0.16 
gi|20336305 B-cell CLL/lymphoma 11A isoform 1 [Homo sapiens]           33   0.20 
gi|20336307 B-cell CLL/lymphoma 11A isoform 2 [Homo sapiens]           33   0.20 
gi|20336313 B-cell CLL/lymphoma 11A isoform 3 [Homo sapiens]           33   0.20 
gi|55953102 tubby like protein 4 isoform 2 [Homo sapiens]              33   0.20 
gi|55953100 tubby like protein 4 isoform 1 [Homo sapiens]              33   0.20 
gi|218505706 ankyrin repeat and SOCS box-containing 14 isoform 1...    33   0.20 

>gi|18254460 splA/ryanodine receptor domain and SOCS box containing
           4 [Homo sapiens]
          Length = 273

 Score =  560 bits (1442), Expect = e-160
 Identities = 273/273 (100%), Positives = 273/273 (100%)

Query: 1   MGQKLSGSLKSVEVREPALRPAKRELRGAEPGRPARLDQLLDMPAAGLAVQLRHAWNPED 60
           MGQKLSGSLKSVEVREPALRPAKRELRGAEPGRPARLDQLLDMPAAGLAVQLRHAWNPED
Sbjct: 1   MGQKLSGSLKSVEVREPALRPAKRELRGAEPGRPARLDQLLDMPAAGLAVQLRHAWNPED 60

Query: 61  RSLNVFVKDDDRLTFHRHPVAQSTDGIRGKVGHARGLHAWQINWPARQRGTHAVVGVATA 120
           RSLNVFVKDDDRLTFHRHPVAQSTDGIRGKVGHARGLHAWQINWPARQRGTHAVVGVATA
Sbjct: 61  RSLNVFVKDDDRLTFHRHPVAQSTDGIRGKVGHARGLHAWQINWPARQRGTHAVVGVATA 120

Query: 121 RAPLHSVGYTALVGSDAESWGWDLGRSRLYHDGKNQPGVAYPAFLGPDEAFALPDSLLVV 180
           RAPLHSVGYTALVGSDAESWGWDLGRSRLYHDGKNQPGVAYPAFLGPDEAFALPDSLLVV
Sbjct: 121 RAPLHSVGYTALVGSDAESWGWDLGRSRLYHDGKNQPGVAYPAFLGPDEAFALPDSLLVV 180

Query: 181 LDMDEGTLSFIVDGQYLGVAFRGLKGKKLYPVVSAVWGHCEVTMRYINGLDPEPLPLMDL 240
           LDMDEGTLSFIVDGQYLGVAFRGLKGKKLYPVVSAVWGHCEVTMRYINGLDPEPLPLMDL
Sbjct: 181 LDMDEGTLSFIVDGQYLGVAFRGLKGKKLYPVVSAVWGHCEVTMRYINGLDPEPLPLMDL 240

Query: 241 CRRSIRSALGRQRLQDISSLPLPQSLKNYLQYQ 273
           CRRSIRSALGRQRLQDISSLPLPQSLKNYLQYQ
Sbjct: 241 CRRSIRSALGRQRLQDISSLPLPQSLKNYLQYQ 273


>gi|18141316 splA/ryanodine receptor domain and SOCS box containing
           1 [Homo sapiens]
          Length = 273

 Score =  434 bits (1117), Expect = e-122
 Identities = 204/273 (74%), Positives = 231/273 (84%)

Query: 1   MGQKLSGSLKSVEVREPALRPAKRELRGAEPGRPARLDQLLDMPAAGLAVQLRHAWNPED 60
           MGQK++G +K+V++R+P  RP K+EL+G +  +P RLD LLDMP     VQL H+WN  D
Sbjct: 1   MGQKVTGGIKTVDMRDPTYRPLKQELQGLDYCKPTRLDLLLDMPPVSYDVQLLHSWNNND 60

Query: 61  RSLNVFVKDDDRLTFHRHPVAQSTDGIRGKVGHARGLHAWQINWPARQRGTHAVVGVATA 120
           RSLNVFVK+DD+L FHRHPVAQSTD IRGKVG+ RGLH WQI W  RQRGTHAVVGVATA
Sbjct: 61  RSLNVFVKEDDKLIFHRHPVAQSTDAIRGKVGYTRGLHVWQITWAMRQRGTHAVVGVATA 120

Query: 121 RAPLHSVGYTALVGSDAESWGWDLGRSRLYHDGKNQPGVAYPAFLGPDEAFALPDSLLVV 180
            APLHSVGYT LVG++ ESWGWDLGR+RLYHDGKNQP   YPAFL PDE F +PDS LV 
Sbjct: 121 DAPLHSVGYTTLVGNNHESWGWDLGRNRLYHDGKNQPSKTYPAFLEPDETFIVPDSFLVA 180

Query: 181 LDMDEGTLSFIVDGQYLGVAFRGLKGKKLYPVVSAVWGHCEVTMRYINGLDPEPLPLMDL 240
           LDMD+GTLSFIVDGQY+GVAFRGLKGKKLYPVVSAVWGHCE+ MRY+NGLDPEPLPLMDL
Sbjct: 181 LDMDDGTLSFIVDGQYMGVAFRGLKGKKLYPVVSAVWGHCEIRMRYLNGLDPEPLPLMDL 240

Query: 241 CRRSIRSALGRQRLQDISSLPLPQSLKNYLQYQ 273
           CRRS+R ALGR+RL +I +LPLP SLK YL YQ
Sbjct: 241 CRRSVRLALGRERLGEIHTLPLPASLKAYLLYQ 273


>gi|226423903 splA/ryanodine receptor domain and SOCS box containing
           2 isoform 1 [Homo sapiens]
          Length = 263

 Score =  267 bits (683), Expect = 6e-72
 Identities = 134/240 (55%), Positives = 164/240 (68%), Gaps = 2/240 (0%)

Query: 34  PARLDQLLDMPAAGLAVQLRHAWNPEDRSLNVFVKDDDRLTFHRHPVAQSTDGIRGKVGH 93
           P  L++LL  P   L  Q RH WNP+D S N+ VK+   L F R PVAQSTDG RGK G+
Sbjct: 26  PEGLEELLSAPPPDLGAQRRHGWNPKDCSENIEVKEGG-LYFERRPVAQSTDGARGKRGY 84

Query: 94  ARGLHAWQINWPARQRGTHAVVGVATARAPLHSVGYTALVGSDAESWGWDLGRSRLYHDG 153
           +RGLHAW+I+WP  QRGTHAVVGVATA APL +  Y AL+GS++ESWGWD+GR +LYH  
Sbjct: 85  SRGLHAWEISWPLEQRGTHAVVGVATALAPLQTDHYAALLGSNSESWGWDIGRGKLYHQS 144

Query: 154 KNQPGVAYPAFLGPDEAFALPDSLLVVLDMDEGTLSFIVDGQYLGVAFRGLKGKKLYPVV 213
           K      YPA     E   +P+ LLVVLDM+EGTL + + G YLG AFRGLKG+ LYP V
Sbjct: 145 KGPGAPQYPAGT-QGEQLEVPERLLVVLDMEEGTLGYAIGGTYLGPAFRGLKGRTLYPAV 203

Query: 214 SAVWGHCEVTMRYINGLDPEPLPLMDLCRRSIRSALGRQRLQDISSLPLPQSLKNYLQYQ 273
           SAVWG C+V +RY+     EP  L+ L R  +R  LG  RL  +S+LPLP ++K YL YQ
Sbjct: 204 SAVWGQCQVRIRYLGERRAEPHSLLHLSRLCVRHNLGDTRLGQVSALPLPPAMKRYLLYQ 263


>gi|14249178 splA/ryanodine receptor domain and SOCS box containing
           2 isoform 1 [Homo sapiens]
          Length = 263

 Score =  267 bits (683), Expect = 6e-72
 Identities = 134/240 (55%), Positives = 164/240 (68%), Gaps = 2/240 (0%)

Query: 34  PARLDQLLDMPAAGLAVQLRHAWNPEDRSLNVFVKDDDRLTFHRHPVAQSTDGIRGKVGH 93
           P  L++LL  P   L  Q RH WNP+D S N+ VK+   L F R PVAQSTDG RGK G+
Sbjct: 26  PEGLEELLSAPPPDLGAQRRHGWNPKDCSENIEVKEGG-LYFERRPVAQSTDGARGKRGY 84

Query: 94  ARGLHAWQINWPARQRGTHAVVGVATARAPLHSVGYTALVGSDAESWGWDLGRSRLYHDG 153
           +RGLHAW+I+WP  QRGTHAVVGVATA APL +  Y AL+GS++ESWGWD+GR +LYH  
Sbjct: 85  SRGLHAWEISWPLEQRGTHAVVGVATALAPLQTDHYAALLGSNSESWGWDIGRGKLYHQS 144

Query: 154 KNQPGVAYPAFLGPDEAFALPDSLLVVLDMDEGTLSFIVDGQYLGVAFRGLKGKKLYPVV 213
           K      YPA     E   +P+ LLVVLDM+EGTL + + G YLG AFRGLKG+ LYP V
Sbjct: 145 KGPGAPQYPAGT-QGEQLEVPERLLVVLDMEEGTLGYAIGGTYLGPAFRGLKGRTLYPAV 203

Query: 214 SAVWGHCEVTMRYINGLDPEPLPLMDLCRRSIRSALGRQRLQDISSLPLPQSLKNYLQYQ 273
           SAVWG C+V +RY+     EP  L+ L R  +R  LG  RL  +S+LPLP ++K YL YQ
Sbjct: 204 SAVWGQCQVRIRYLGERRAEPHSLLHLSRLCVRHNLGDTRLGQVSALPLPPAMKRYLLYQ 263


>gi|226423905 splA/ryanodine receptor domain and SOCS box containing
           2 isoform 2 [Homo sapiens]
          Length = 267

 Score =  233 bits (595), Expect = 1e-61
 Identities = 114/194 (58%), Positives = 138/194 (71%), Gaps = 2/194 (1%)

Query: 34  PARLDQLLDMPAAGLAVQLRHAWNPEDRSLNVFVKDDDRLTFHRHPVAQSTDGIRGKVGH 93
           P  L++LL  P   L  Q RH WNP+D S N+ VK+   L F R PVAQSTDG RGK G+
Sbjct: 26  PEGLEELLSAPPPDLGAQRRHGWNPKDCSENIEVKEGG-LYFERRPVAQSTDGARGKRGY 84

Query: 94  ARGLHAWQINWPARQRGTHAVVGVATARAPLHSVGYTALVGSDAESWGWDLGRSRLYHDG 153
           +RGLHAW+I+WP  QRGTHAVVGVATA APL +  Y AL+GS++ESWGWD+GR +LYH  
Sbjct: 85  SRGLHAWEISWPLEQRGTHAVVGVATALAPLQTDHYAALLGSNSESWGWDIGRGKLYHQS 144

Query: 154 KNQPGVAYPAFLGPDEAFALPDSLLVVLDMDEGTLSFIVDGQYLGVAFRGLKGKKLYPVV 213
           K      YPA     E   +P+ LLVVLDM+EGTL + + G YLG AFRGLKG+ LYP V
Sbjct: 145 KGPGAPQYPAGT-QGEQLEVPERLLVVLDMEEGTLGYAIGGTYLGPAFRGLKGRTLYPAV 203

Query: 214 SAVWGHCEVTMRYI 227
           SAVWG C+V +RY+
Sbjct: 204 SAVWGQCQVRIRYL 217


>gi|157743247 F-box protein 45 [Homo sapiens]
          Length = 286

 Score =  151 bits (381), Expect = 7e-37
 Identities = 82/193 (42%), Positives = 125/193 (64%), Gaps = 6/193 (3%)

Query: 36  RLDQLLDMPAAGLAVQ-LRHAWNPEDRSLNVFVKDDDRLTFHRHPVAQSTDGIRGKVGHA 94
           R D L ++P+    ++  +HA++  D S NV++K +   T HR+P+AQSTDG R K+G +
Sbjct: 93  RTDILCNLPSYKAKIRAFQHAFSTNDCSRNVYIKKNG-FTLHRNPIAQSTDGARTKIGFS 151

Query: 95  RGLHAWQINWPARQRGTHAVVGVATARAPLHSVGYTALVGSDAESWGWDLGRSRLYHDGK 154
            G HAW++ W     GT AV+G+AT RAP+   GY AL+GSD +SWGW+L  + L H+G 
Sbjct: 152 EGRHAWEVWWEG-PLGTVAVIGIATKRAPMQCQGYVALLGSDDQSWGWNLVDNNLLHNG- 209

Query: 155 NQPGVAYPAFLGPDEAFALPDSLLVVLDMDEGTLSFIVDGQYLGVAFRGLKGKKLYPVVS 214
            +   ++P      + + + + + V+LDM++ TL+F    ++LGVAFRGL    LYP VS
Sbjct: 210 -EVNGSFPQCNNAPK-YQIGERIRVILDMEDKTLAFERGYEFLGVAFRGLPKVCLYPAVS 267

Query: 215 AVWGHCEVTMRYI 227
           AV+G+ EVT+ Y+
Sbjct: 268 AVYGNTEVTLVYL 280


>gi|27552770 splA/ryanodine receptor domain and SOCS box containing
           3 [Homo sapiens]
          Length = 355

 Score = 61.6 bits (148), Expect = 7e-10
 Identities = 59/219 (26%), Positives = 91/219 (41%), Gaps = 20/219 (9%)

Query: 56  WNPEDRSLNVFVKDDDRLTFHRHPVAQSTDGIRGKVGHARGLHAWQINWPARQRGTHAVV 115
           W+  ++S    +  D+R        +  T  IRG      G H W+I   +   GT  +V
Sbjct: 107 WDDLNKSSATLLSCDNRKVSFHMEYSCGTAAIRGTKELGEGQHFWEIKMTSPVYGTDMMV 166

Query: 116 GVATARAPLHSVGYT--ALVGSDAESWGWDLGRSRLYHDGKNQPGVAYPAFLGPDEAFAL 173
           G+ T+   L    +T  +L+G D +SWG  L  + L H   ++   +          F  
Sbjct: 167 GIGTSDVDLDKYRHTFCSLLGRDEDSWG--LSYTGLLHHKGDKTSFS--------SRFGQ 216

Query: 174 PDSLLVVLDMDEGTLSFIVDGQYLGVAFRGLKGKKLYPVV--SAVWGHCEVTMRYINGLD 231
              + V LD   GTL+F  + + +GVA   L+ K+ YP+V  +A     +VT    +   
Sbjct: 217 GSIIGVHLDTWHGTLTFFKNRKCIGVAATKLQNKRFYPMVCSTAARSSMKVTRSCASATS 276

Query: 232 PEPLPLMDLCRRSIRSALGRQRLQDISSLPLPQSLKNYL 270
                L  LC   +R  L       +  LPLP  LK  L
Sbjct: 277 -----LQYLCCHRLRQ-LRPDSGDTLEGLPLPPGLKQVL 309


>gi|18252778 ankyrin repeat and SOCS box-containing protein 2 [Homo
           sapiens]
          Length = 587

 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 18/40 (45%), Positives = 27/40 (67%)

Query: 234 PLPLMDLCRRSIRSALGRQRLQDISSLPLPQSLKNYLQYQ 273
           P PL  LCR  +R A+G+ R++ + +LPLP  L  YL+Y+
Sbjct: 545 PRPLAHLCRLRVRKAIGKYRIKLLDTLPLPGRLIRYLKYE 584


>gi|38176283 ankyrin repeat and SOCS box-containing protein 7
           isoform 2 [Homo sapiens]
          Length = 318

 Score = 41.6 bits (96), Expect = 8e-04
 Identities = 20/72 (27%), Positives = 39/72 (54%)

Query: 202 RGLKGKKLYPVVSAVWGHCEVTMRYINGLDPEPLPLMDLCRRSIRSALGRQRLQDISSLP 261
           R  +G+    V  ++ G     + ++  +  +P  L DLCR  IR  +G Q L+ +  LP
Sbjct: 243 RNYEGQTPLAVSISISGSSRPCLDFLQEVTRQPRNLQDLCRIKIRQCIGLQNLKLLDELP 302

Query: 262 LPQSLKNYLQYQ 273
           + + +K+YL+++
Sbjct: 303 IAKVMKDYLKHK 314


>gi|18254476 ankyrin repeat and SOCS box-containing protein 5 [Homo
           sapiens]
          Length = 329

 Score = 41.6 bits (96), Expect = 8e-04
 Identities = 21/40 (52%), Positives = 25/40 (62%)

Query: 234 PLPLMDLCRRSIRSALGRQRLQDISSLPLPQSLKNYLQYQ 273
           P  L  LCR  IRS +G+ RL  I  L LP  LKN+LQY+
Sbjct: 290 PSSLYQLCRLCIRSYIGKPRLHLIPQLQLPTLLKNFLQYR 329


>gi|94721248 ankyrin repeat and SOCS box-containing protein 1 [Homo
           sapiens]
          Length = 335

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 19/40 (47%), Positives = 27/40 (67%)

Query: 234 PLPLMDLCRRSIRSALGRQRLQDISSLPLPQSLKNYLQYQ 273
           P  L+ LCR ++R ALG+ RL  I SLPLP  +K +L ++
Sbjct: 296 PRTLLCLCRVAVRRALGKHRLHLIPSLPLPDPIKKFLLHE 335


>gi|126131099 guanine nucleotide exchange factor p532 [Homo sapiens]
          Length = 4861

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 30/122 (24%), Positives = 52/122 (42%), Gaps = 14/122 (11%)

Query: 92   GHARGLHAWQINWPARQRGTHAVVGVATARAPLHSVGYTALVGSDAESWGWDLGRSRLYH 151
            G   G + W+       RG      V  +R P+H   +     + ++ W +      LYH
Sbjct: 2066 GVTSGCYQWKFYIVKENRGNEGTC-VGVSRWPVHDFNHR----TTSDMWLYRAYSGNLYH 2120

Query: 152  DGKNQPGVAYPAFLGPDEAFALPDSLLVVLDMDEGTLSFIVDGQYLGVAFRGLKGKKLYP 211
            +G+    ++         +F   D +  VLDM+  T+SF  +G+   +AF  +   +LYP
Sbjct: 2121 NGEQTLTLS---------SFTQGDFITCVLDMEARTISFGKNGEEPKLAFEDVDAAELYP 2171

Query: 212  VV 213
             V
Sbjct: 2172 CV 2173


>gi|22208951 ankyrin repeat and SOCS box-containing protein 3
           isoform b [Homo sapiens]
          Length = 445

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 22/40 (55%), Positives = 27/40 (67%), Gaps = 3/40 (7%)

Query: 237 LMDLCRRSIRSALGRQRLQD---ISSLPLPQSLKNYLQYQ 273
           L  LCR  IRS+L  +RL+    IS LPLP+SL NYL Y+
Sbjct: 389 LTHLCRLEIRSSLKSERLRSDSYISQLPLPRSLHNYLLYE 428


>gi|7705831 ankyrin repeat and SOCS box-containing protein 3 isoform
           a [Homo sapiens]
          Length = 518

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 22/40 (55%), Positives = 27/40 (67%), Gaps = 3/40 (7%)

Query: 237 LMDLCRRSIRSALGRQRLQD---ISSLPLPQSLKNYLQYQ 273
           L  LCR  IRS+L  +RL+    IS LPLP+SL NYL Y+
Sbjct: 462 LTHLCRLEIRSSLKSERLRSDSYISQLPLPRSLHNYLLYE 501


>gi|134288906 tripartite motif-containing 67 [Homo sapiens]
          Length = 783

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 31/127 (24%), Positives = 56/127 (44%), Gaps = 24/127 (18%)

Query: 87  IRGKVGHARGLHAWQINWPARQRGTHAVVGVATARAPLHSVGYTALVGSDAESWGWDLGR 146
           + G    ++G+H W+++            GVA A     SV    ++G D ++W   +  
Sbjct: 640 VLGTAAFSKGVHYWELHVDRYDNHPDPAFGVARA-----SVVKDMMLGKDDKAWAMYVDN 694

Query: 147 SRLY------HDGKNQPGVAYPAFLGPDEAFALPDSLLVVLDMDEGTLSFIVDGQYLG-V 199
           +R +      H  + + GV   A +G            V+LD+++ TL+F ++GQ  G  
Sbjct: 695 NRSWFMHCNSHTNRTEGGVCKGATVG------------VLLDLNKHTLTFFINGQQQGPT 742

Query: 200 AFRGLKG 206
           AF  + G
Sbjct: 743 AFSHVDG 749


>gi|37588869 ring finger protein 123 [Homo sapiens]
          Length = 1314

 Score = 38.5 bits (88), Expect = 0.006
 Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 13/85 (15%)

Query: 133 VGSDAESWGWDLGRSRLYHDGKNQPGVAYPAFLGPDEAFALPDSLLVVLDMDEGTLSFIV 192
           VG    S+ +D  R R ++      G          +A+A  D +  ++D+D+GTLSF +
Sbjct: 164 VGDTHNSYAYDGNRVRKWNVTTTNYG----------KAWAAGDIVSCLIDLDDGTLSFCL 213

Query: 193 DGQYLGVAFRGLK---GKKLYPVVS 214
           +G  LG AF  L    G   +P +S
Sbjct: 214 NGVSLGTAFENLSRGLGMAYFPAIS 238


>gi|190341104 tripartite motif protein 9 isoform 1 [Homo sapiens]
          Length = 710

 Score = 38.5 bits (88), Expect = 0.006
 Identities = 30/135 (22%), Positives = 58/135 (42%), Gaps = 25/135 (18%)

Query: 87  IRGKVGHARGLHAWQINWPARQRGTHAVVGVATARAPLHSVGYTALVGSDAESWGWDLGR 146
           + GK G ++G+H W++             GVA        V    ++G D ++W   +  
Sbjct: 568 VLGKTGFSKGIHYWELTVDRYDNHPDPAFGVARM-----DVMKDVMLGKDDKAWAMYVDN 622

Query: 147 SRLY------HDGKNQPGVAYPAFLGPDEAFALPDSLLVVLDMDEGTLSFIVDGQYLG-V 199
           +R +      H  + + G+   A +G            V+LD++   L+F ++ +  G +
Sbjct: 623 NRSWFMHNNSHTNRTEGGITKGATIG------------VLLDLNRKNLTFFINDEQQGPI 670

Query: 200 AFRGLKGKKLYPVVS 214
           AF  ++G   +P VS
Sbjct: 671 AFDNVEG-LFFPAVS 684


>gi|4826686 DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 [Homo sapiens]
          Length = 740

 Score = 35.4 bits (80), Expect = 0.054
 Identities = 43/168 (25%), Positives = 74/168 (44%), Gaps = 25/168 (14%)

Query: 47  GLAVQLRHAWNPEDRSLNVFVKDDDRLTFHRHPVAQSTDGIRGKVGHARGLHAWQINWPA 106
           G +V  +   NP DR  + F    D L      V +   G R   G  +G H ++++   
Sbjct: 84  GASVLNKWQMNPYDRG-SAFAIGSDGLCCQSREVKE-WHGCRATKGLMKGKHYYEVS--C 139

Query: 107 RQRGTHAVVGVATARAPLHSVGYTALVGSDAESWGWDLGRSRLYHDGKNQPGVAYPAFLG 166
             +G    VG +T +A L        +G+D   +G+  G  +  H+ +         F  
Sbjct: 140 HDQGL-CRVGWSTMQASLD-------LGTDKFGFGFG-GTGKKSHNKQ---------FDN 181

Query: 167 PDEAFALPDSLLVVLDMDEGTLSFIVDGQYLGVAFR---GLKGKKLYP 211
             E F + D++   LD+D+G + F  +G+ LG+AF     +K + L+P
Sbjct: 182 YGEEFTMHDTIGCYLDIDKGHVKFSKNGKDLGLAFEIPPHMKNQALFP 229


>gi|22208957 ankyrin repeat and SOCS box-containing protein 13 [Homo
           sapiens]
          Length = 278

 Score = 35.4 bits (80), Expect = 0.054
 Identities = 17/39 (43%), Positives = 24/39 (61%)

Query: 234 PLPLMDLCRRSIRSALGRQRLQDISSLPLPQSLKNYLQY 272
           PL L  LCR ++R A G + L+ I+ L +P  L +YL Y
Sbjct: 239 PLTLSQLCRVNLRKATGVRGLEKIAKLNIPPRLIDYLSY 277


>gi|18254474 ankyrin repeat and SOCS box-containing protein 11
           isoform a [Homo sapiens]
          Length = 323

 Score = 35.0 bits (79), Expect = 0.070
 Identities = 18/40 (45%), Positives = 22/40 (55%)

Query: 234 PLPLMDLCRRSIRSALGRQRLQDISSLPLPQSLKNYLQYQ 273
           P  L  LCR  +R  LGR   Q I  L LP+ L+ +L YQ
Sbjct: 284 PPALSQLCRLCVRKCLGRACHQAIHKLHLPEPLERFLLYQ 323


>gi|60218887 ankyrin repeat and SOCS box-containing protein 11
           isoform b [Homo sapiens]
          Length = 302

 Score = 35.0 bits (79), Expect = 0.070
 Identities = 18/40 (45%), Positives = 22/40 (55%)

Query: 234 PLPLMDLCRRSIRSALGRQRLQDISSLPLPQSLKNYLQYQ 273
           P  L  LCR  +R  LGR   Q I  L LP+ L+ +L YQ
Sbjct: 263 PPALSQLCRLCVRKCLGRACHQAIHKLHLPEPLERFLLYQ 302


>gi|72534772 ankyrin repeat and SOCS box-containing 9 isoform 1
           [Homo sapiens]
          Length = 294

 Score = 34.3 bits (77), Expect = 0.12
 Identities = 17/37 (45%), Positives = 21/37 (56%)

Query: 234 PLPLMDLCRRSIRSALGRQRLQDISSLPLPQSLKNYL 270
           P  LM LCR  IR   G Q+   I+ L LP+ LK +L
Sbjct: 255 PPSLMQLCRLRIRKCFGIQQHHKITKLVLPEDLKQFL 291


>gi|154354992 B-box and SPRY domain containing [Homo sapiens]
          Length = 402

 Score = 34.3 bits (77), Expect = 0.12
 Identities = 31/113 (27%), Positives = 47/113 (41%), Gaps = 17/113 (15%)

Query: 59  EDRSLNVFVK-DDDR--LTFHRHPVAQSTDGIR---------GKVGHARGLHAWQINWPA 106
           ++R+++ F++  DDR  LTF         DG                  GLHAW +N   
Sbjct: 235 DERTVSPFLQLSDDRKTLTFSTKKSKACADGPERFDHWPNALAATSFQNGLHAWMVNV-- 292

Query: 107 RQRGTHAVVGVATARAPLHSVGYTALVGSDAESWGWDL--GRSRLYHDGKNQP 157
            Q      VGVA+   P    G    +G +A SW +       R  H+G+++P
Sbjct: 293 -QNSCAYKVGVASGHLPRKGSGSDCRLGHNAFSWVFSRYDQEFRFSHNGQHEP 344


>gi|13129098 ankyrin repeat and SOCS box-containing 8 [Homo sapiens]
          Length = 288

 Score = 33.9 bits (76), Expect = 0.16
 Identities = 19/38 (50%), Positives = 23/38 (60%), Gaps = 1/38 (2%)

Query: 234 PLPLMDLCRRSIRSALGRQRLQD-ISSLPLPQSLKNYL 270
           P  L  L R ++R +LG Q L D +  LPLP SLK YL
Sbjct: 247 PGTLKTLARYAVRRSLGLQYLPDAVKGLPLPASLKEYL 284


>gi|20336305 B-cell CLL/lymphoma 11A isoform 1 [Homo sapiens]
          Length = 835

 Score = 33.5 bits (75), Expect = 0.20
 Identities = 17/61 (27%), Positives = 32/61 (52%)

Query: 37  LDQLLDMPAAGLAVQLRHAWNPEDRSLNVFVKDDDRLTFHRHPVAQSTDGIRGKVGHARG 96
           L++ +D P +   ++++ A NP +  + V  +DDD L+     +    + I  K+ H RG
Sbjct: 77  LEKAVDKPPSPSPIEMKKASNPVEVGIQVTPEDDDCLSTSSRGICPKQEHIADKLLHWRG 136

Query: 97  L 97
           L
Sbjct: 137 L 137


>gi|20336307 B-cell CLL/lymphoma 11A isoform 2 [Homo sapiens]
          Length = 773

 Score = 33.5 bits (75), Expect = 0.20
 Identities = 17/61 (27%), Positives = 32/61 (52%)

Query: 37  LDQLLDMPAAGLAVQLRHAWNPEDRSLNVFVKDDDRLTFHRHPVAQSTDGIRGKVGHARG 96
           L++ +D P +   ++++ A NP +  + V  +DDD L+     +    + I  K+ H RG
Sbjct: 77  LEKAVDKPPSPSPIEMKKASNPVEVGIQVTPEDDDCLSTSSRGICPKQEHIADKLLHWRG 136

Query: 97  L 97
           L
Sbjct: 137 L 137


>gi|20336313 B-cell CLL/lymphoma 11A isoform 3 [Homo sapiens]
          Length = 243

 Score = 33.5 bits (75), Expect = 0.20
 Identities = 17/61 (27%), Positives = 32/61 (52%)

Query: 37  LDQLLDMPAAGLAVQLRHAWNPEDRSLNVFVKDDDRLTFHRHPVAQSTDGIRGKVGHARG 96
           L++ +D P +   ++++ A NP +  + V  +DDD L+     +    + I  K+ H RG
Sbjct: 77  LEKAVDKPPSPSPIEMKKASNPVEVGIQVTPEDDDCLSTSSRGICPKQEHIADKLLHWRG 136

Query: 97  L 97
           L
Sbjct: 137 L 137


>gi|55953102 tubby like protein 4 isoform 2 [Homo sapiens]
          Length = 678

 Score = 33.5 bits (75), Expect = 0.20
 Identities = 31/113 (27%), Positives = 52/113 (46%), Gaps = 21/113 (18%)

Query: 177 LLVVLDMDEGT-LSFIVDGQYLG---VAFRGLKGKKLY--------PVVSAVWGHCEVTM 224
           LL V  M+  T L  + +G  L    V F  ++G+ ++        P++S  WGH +  +
Sbjct: 298 LLAVAGMERQTQLGELPNGPLLKSAMVKFYNVRGEHIFTLDTLVQRPIISICWGHRDSRL 357

Query: 225 -------RYINGLDPEPLPLMDLCRRSIRSALGRQRLQDISSLPLPQSLKNYL 270
                   Y+  ++     L  LC+++I S L   +  D+S L LP  L +YL
Sbjct: 358 LMASGPALYVVRVEHRVSSLQLLCQQAIASTLREDK--DVSKLTLPPRLCSYL 408


>gi|55953100 tubby like protein 4 isoform 1 [Homo sapiens]
          Length = 1543

 Score = 33.5 bits (75), Expect = 0.20
 Identities = 31/113 (27%), Positives = 52/113 (46%), Gaps = 21/113 (18%)

Query: 177 LLVVLDMDEGT-LSFIVDGQYLG---VAFRGLKGKKLY--------PVVSAVWGHCEVTM 224
           LL V  M+  T L  + +G  L    V F  ++G+ ++        P++S  WGH +  +
Sbjct: 298 LLAVAGMERQTQLGELPNGPLLKSAMVKFYNVRGEHIFTLDTLVQRPIISICWGHRDSRL 357

Query: 225 -------RYINGLDPEPLPLMDLCRRSIRSALGRQRLQDISSLPLPQSLKNYL 270
                   Y+  ++     L  LC+++I S L   +  D+S L LP  L +YL
Sbjct: 358 LMASGPALYVVRVEHRVSSLQLLCQQAIASTLREDK--DVSKLTLPPRLCSYL 408


>gi|218505706 ankyrin repeat and SOCS box-containing 14 isoform 1
           [Homo sapiens]
          Length = 423

 Score = 33.5 bits (75), Expect = 0.20
 Identities = 19/43 (44%), Positives = 24/43 (55%), Gaps = 3/43 (6%)

Query: 234 PLPLMDLCRRSIRSALGRQRLQ---DISSLPLPQSLKNYLQYQ 273
           P  L  LCR  IR  +GR  L+    +S LPLP  LK Y+ Y+
Sbjct: 367 PRSLKHLCRLKIRKCMGRLHLRCPVFMSFLPLPNRLKAYVLYK 409


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.138    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,955,313
Number of Sequences: 37866
Number of extensions: 507917
Number of successful extensions: 1130
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 1083
Number of HSP's gapped (non-prelim): 55
length of query: 273
length of database: 18,247,518
effective HSP length: 101
effective length of query: 172
effective length of database: 14,423,052
effective search space: 2480764944
effective search space used: 2480764944
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.