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Search of human proteins with 18201894
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18201894 T-box 5 isoform 3 [Homo sapiens]
(468 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18201894 T-box 5 isoform 3 [Homo sapiens] 983 0.0
gi|18201892 T-box 5 isoform 1 [Homo sapiens] 983 0.0
gi|31652232 T-box 5 isoform 1 [Homo sapiens] 983 0.0
gi|18201896 T-box 5 isoform 2 [Homo sapiens] 582 e-166
gi|18129690 T-box 4 [Homo sapiens] 506 e-143
gi|47419905 T-box 3 protein isoform 1 [Homo sapiens] 251 1e-66
gi|197333868 T-box 2 [Homo sapiens] 247 2e-65
gi|117676399 T-box transcription factor TBX20 [Homo sapiens] 240 2e-63
gi|47419907 T-box 3 protein isoform 2 [Homo sapiens] 239 3e-63
gi|5174711 T-box 1 isoform B [Homo sapiens] 239 3e-63
gi|18104952 T-box 1 isoform C [Homo sapiens] 238 9e-63
gi|18104950 T-box 1 isoform A [Homo sapiens] 238 1e-62
gi|18201900 T-box 6 [Homo sapiens] 236 3e-62
gi|32567784 T-box 10 [Homo sapiens] 231 1e-60
gi|55770860 T-box 15 [Homo sapiens] 226 4e-59
gi|122937456 T-box 18 [Homo sapiens] 223 3e-58
gi|4507339 transcription factor T [Homo sapiens] 209 3e-54
gi|122937388 MAX gene associated [Homo sapiens] 207 1e-53
gi|7019549 T-box 21 [Homo sapiens] 200 2e-51
gi|158187509 T-box 22 isoform 1 [Homo sapiens] 198 1e-50
gi|18375603 T-box 22 isoform 1 [Homo sapiens] 198 1e-50
gi|5730081 T-box, brain, 1 [Homo sapiens] 196 4e-50
gi|4827024 T-box 19 [Homo sapiens] 194 1e-49
gi|22538470 eomesodermin [Homo sapiens] 192 7e-49
gi|158187511 T-box 22 isoform 2 [Homo sapiens] 159 7e-39
gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo ... 43 7e-04
gi|239748171 PREDICTED: similar to roundabout 1 isoform 2 [Homo ... 43 7e-04
gi|224994173 roundabout 1 isoform d [Homo sapiens] 42 0.001
gi|224994171 roundabout 1 isoform c [Homo sapiens] 42 0.001
gi|19743806 roundabout 1 isoform b [Homo sapiens] 42 0.001
>gi|18201894 T-box 5 isoform 3 [Homo sapiens]
Length = 468
Score = 983 bits (2541), Expect = 0.0
Identities = 468/468 (100%), Positives = 468/468 (100%)
Query: 1 MEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPAD 60
MEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPAD
Sbjct: 1 MEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPAD 60
Query: 61 DHRYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH 120
DHRYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH
Sbjct: 61 DHRYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH 120
Query: 121 IILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENN 180
IILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENN
Sbjct: 121 IILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENN 180
Query: 181 PFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQ 240
PFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQ
Sbjct: 181 PFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQ 240
Query: 241 YQCENGVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSEE 300
YQCENGVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSEE
Sbjct: 241 YQCENGVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSEE 300
Query: 301 DSFYRSSYPQQQGLGASYRTESAQRQACMYASSAPPSEPVPSLEDISCNTWPSMPSYSSC 360
DSFYRSSYPQQQGLGASYRTESAQRQACMYASSAPPSEPVPSLEDISCNTWPSMPSYSSC
Sbjct: 301 DSFYRSSYPQQQGLGASYRTESAQRQACMYASSAPPSEPVPSLEDISCNTWPSMPSYSSC 360
Query: 361 TVTTVQPMDRLPYQHFSAHFTSGPLVPRLAGMANHGSPQLGEGMFQHQTSVAHQPVVRQC 420
TVTTVQPMDRLPYQHFSAHFTSGPLVPRLAGMANHGSPQLGEGMFQHQTSVAHQPVVRQC
Sbjct: 361 TVTTVQPMDRLPYQHFSAHFTSGPLVPRLAGMANHGSPQLGEGMFQHQTSVAHQPVVRQC 420
Query: 421 GPQTGLQSPGTLQPPEFLYSHGVPRTLSPHQYHSVHGVGMVPEWSDNS 468
GPQTGLQSPGTLQPPEFLYSHGVPRTLSPHQYHSVHGVGMVPEWSDNS
Sbjct: 421 GPQTGLQSPGTLQPPEFLYSHGVPRTLSPHQYHSVHGVGMVPEWSDNS 468
>gi|18201892 T-box 5 isoform 1 [Homo sapiens]
Length = 518
Score = 983 bits (2541), Expect = 0.0
Identities = 468/468 (100%), Positives = 468/468 (100%)
Query: 1 MEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPAD 60
MEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPAD
Sbjct: 51 MEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPAD 110
Query: 61 DHRYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH 120
DHRYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH
Sbjct: 111 DHRYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH 170
Query: 121 IILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENN 180
IILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENN
Sbjct: 171 IILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENN 230
Query: 181 PFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQ 240
PFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQ
Sbjct: 231 PFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQ 290
Query: 241 YQCENGVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSEE 300
YQCENGVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSEE
Sbjct: 291 YQCENGVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSEE 350
Query: 301 DSFYRSSYPQQQGLGASYRTESAQRQACMYASSAPPSEPVPSLEDISCNTWPSMPSYSSC 360
DSFYRSSYPQQQGLGASYRTESAQRQACMYASSAPPSEPVPSLEDISCNTWPSMPSYSSC
Sbjct: 351 DSFYRSSYPQQQGLGASYRTESAQRQACMYASSAPPSEPVPSLEDISCNTWPSMPSYSSC 410
Query: 361 TVTTVQPMDRLPYQHFSAHFTSGPLVPRLAGMANHGSPQLGEGMFQHQTSVAHQPVVRQC 420
TVTTVQPMDRLPYQHFSAHFTSGPLVPRLAGMANHGSPQLGEGMFQHQTSVAHQPVVRQC
Sbjct: 411 TVTTVQPMDRLPYQHFSAHFTSGPLVPRLAGMANHGSPQLGEGMFQHQTSVAHQPVVRQC 470
Query: 421 GPQTGLQSPGTLQPPEFLYSHGVPRTLSPHQYHSVHGVGMVPEWSDNS 468
GPQTGLQSPGTLQPPEFLYSHGVPRTLSPHQYHSVHGVGMVPEWSDNS
Sbjct: 471 GPQTGLQSPGTLQPPEFLYSHGVPRTLSPHQYHSVHGVGMVPEWSDNS 518
>gi|31652232 T-box 5 isoform 1 [Homo sapiens]
Length = 518
Score = 983 bits (2541), Expect = 0.0
Identities = 468/468 (100%), Positives = 468/468 (100%)
Query: 1 MEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPAD 60
MEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPAD
Sbjct: 51 MEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPAD 110
Query: 61 DHRYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH 120
DHRYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH
Sbjct: 111 DHRYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH 170
Query: 121 IILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENN 180
IILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENN
Sbjct: 171 IILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENN 230
Query: 181 PFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQ 240
PFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQ
Sbjct: 231 PFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQ 290
Query: 241 YQCENGVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSEE 300
YQCENGVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSEE
Sbjct: 291 YQCENGVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSEE 350
Query: 301 DSFYRSSYPQQQGLGASYRTESAQRQACMYASSAPPSEPVPSLEDISCNTWPSMPSYSSC 360
DSFYRSSYPQQQGLGASYRTESAQRQACMYASSAPPSEPVPSLEDISCNTWPSMPSYSSC
Sbjct: 351 DSFYRSSYPQQQGLGASYRTESAQRQACMYASSAPPSEPVPSLEDISCNTWPSMPSYSSC 410
Query: 361 TVTTVQPMDRLPYQHFSAHFTSGPLVPRLAGMANHGSPQLGEGMFQHQTSVAHQPVVRQC 420
TVTTVQPMDRLPYQHFSAHFTSGPLVPRLAGMANHGSPQLGEGMFQHQTSVAHQPVVRQC
Sbjct: 411 TVTTVQPMDRLPYQHFSAHFTSGPLVPRLAGMANHGSPQLGEGMFQHQTSVAHQPVVRQC 470
Query: 421 GPQTGLQSPGTLQPPEFLYSHGVPRTLSPHQYHSVHGVGMVPEWSDNS 468
GPQTGLQSPGTLQPPEFLYSHGVPRTLSPHQYHSVHGVGMVPEWSDNS
Sbjct: 471 GPQTGLQSPGTLQPPEFLYSHGVPRTLSPHQYHSVHGVGMVPEWSDNS 518
>gi|18201896 T-box 5 isoform 2 [Homo sapiens]
Length = 349
Score = 582 bits (1500), Expect = e-166
Identities = 281/288 (97%), Positives = 282/288 (97%), Gaps = 4/288 (1%)
Query: 1 MEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPAD 60
MEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPAD
Sbjct: 51 MEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPAD 110
Query: 61 DHRYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH 120
DHRYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH
Sbjct: 111 DHRYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH 170
Query: 121 IILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENN 180
IILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENN
Sbjct: 171 IILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENN 230
Query: 181 PFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQ 240
PFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQ
Sbjct: 231 PFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQ 290
Query: 241 YQCENGVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPY 288
YQCENGVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRK E DHP+
Sbjct: 291 YQCENGVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRKGE----CDHPW 334
>gi|18129690 T-box 4 [Homo sapiens]
Length = 545
Score = 506 bits (1304), Expect = e-143
Identities = 281/491 (57%), Positives = 333/491 (67%), Gaps = 35/491 (7%)
Query: 1 MEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPAD 60
+E IKV LHE+ELW KFHE GTEMIITKAGRRMFPSYKVKVTG+NPKTKYILL+DIVPAD
Sbjct: 64 IENIKVGLHEKELWKKFHEAGTEMIITKAGRRMFPSYKVKVTGMNPKTKYILLIDIVPAD 123
Query: 61 DHRYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH 120
DHRYKF DNKW V GKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH
Sbjct: 124 DHRYKFCDNKWMVAGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH 183
Query: 121 IILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENN 180
IILNSMHKYQPRLHIVKADENN FGSKNTAFCTHVFPET+FI+VTSYQNHKITQLKIENN
Sbjct: 184 IILNSMHKYQPRLHIVKADENNAFGSKNTAFCTHVFPETSFISVTSYQNHKITQLKIENN 243
Query: 181 PFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQ 240
PFAKGFRGSDD +L R++R+QSKEYPV+ +S +RQ++ S + + L +
Sbjct: 244 PFAKGFRGSDDSDL-RVARLQSKEYPVISKSIMRQRLISPQLSATPDVGPLLGTHQALQH 302
Query: 241 YQCENGVS---GPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSP 297
YQ ENG QDL P + +P ++ S YHC KR+ + D P K+ Y+E
Sbjct: 303 YQHENGAHSQLAEPQDL--PLSTFPTQRDSSLFYHCLKRR-DGTRHLDLPCKRSYLEAPS 359
Query: 298 S-EEDSFYRSSYP-QQQGLGASYRTESAQRQACMYASSAPPSEPVPSLED-----ISCNT 350
S ED ++RS P QQ L SY +E R+ACMY+ S P V ++D +SCN
Sbjct: 360 SVGEDHYFRSPPPYDQQMLSPSYCSEVTPREACMYSGSGPEIAGVSGVDDLPPPPLSCNM 419
Query: 351 WPSMPSYSSCTVTTVQPMDRLPYQHFSAHFTSGPLVPRLAGMANHGSPQLGEGMFQHQTS 410
W S+ Y+S +VQ M+ +PYQ F HFT+ ++PRL ++ S G F
Sbjct: 420 WTSVSPYTS---YSVQTMETVPYQPFPTHFTATTMMPRLPTLSAQSSQPPGNAHFSVYNQ 476
Query: 411 VAHQPVVRQCGP------QTGLQSPGTLQPP--------EFLYSHGVPRTL-SPHQYHSV 455
++ Q VR+ GP + GL +PP EFLYS + S QYHS
Sbjct: 477 LS-QSQVRERGPSASFPRERGLPQGCERKPPSPHLNAANEFLYSQTFSLSRESSLQYHS- 534
Query: 456 HGVGMVPEWSD 466
G+G V W+D
Sbjct: 535 -GMGTVENWTD 544
>gi|47419905 T-box 3 protein isoform 1 [Homo sapiens]
Length = 723
Score = 251 bits (641), Expect = 1e-66
Identities = 162/424 (38%), Positives = 223/424 (52%), Gaps = 37/424 (8%)
Query: 5 KVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRY 64
KV L +ELW +FH+ GTEM+ITK+GRRMFP +KV+ +GL+ K KYILLMDI+ ADD RY
Sbjct: 104 KVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRY 163
Query: 65 KFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILN 124
KF +++W V GKA+P MP R+Y+HPDSPATG WM ++V+F KLKLTNN D G ILN
Sbjct: 164 KFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTILN 223
Query: 125 SMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAK 184
SMHKYQPR HIV+A N+ + F T++FPET FIAVT+YQN KITQLKI+NNPFAK
Sbjct: 224 SMHKYQPRFHIVRA--NDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFAK 281
Query: 185 GFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCE 244
GFR + + + ++ + V ++ S+ S SSE A + + S
Sbjct: 282 GFRDTGNGRREKRKQLTLQSMRVFDERHKKENGTSDES--SSEQAAFNCFAQASSPAAST 339
Query: 245 NGVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTT--DHPYKKPYMETSPSEEDS 302
G S +DL P E + + + STT + P + + SP+ +
Sbjct: 340 VGTSN-LKDLCPSEGESDAEAESKEEHGPEACDAAKISTTTSEEPCRD---KGSPAVKAH 395
Query: 303 FYRSSYPQQQGLGASYRTESAQRQACMYASS---------APPSEPVPSLEDISCNTWPS 353
+ + P+ G +S A + +S+ +P E + P
Sbjct: 396 LFAAERPRDSGRLDKASPDSRHSPATISSSTRGLGAEERRSPVREGTAPAKVEEARALPG 455
Query: 354 MPSYSSCTVTTVQPMDRLPYQHFSAHFTSGPL-----VPRLAGMANHGSPQLGEGMFQHQ 408
+++ TV T +AH GPL P LAG G +F H
Sbjct: 456 KEAFAPLTVQT---------DAAAAHLAQGPLPGLGFAPGLAGQQFFN----GHPLFLHP 502
Query: 409 TSVA 412
+ A
Sbjct: 503 SQFA 506
>gi|197333868 T-box 2 [Homo sapiens]
Length = 712
Score = 247 bits (630), Expect = 2e-65
Identities = 121/183 (66%), Positives = 145/183 (79%), Gaps = 2/183 (1%)
Query: 5 KVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRY 64
KV L +ELW +FH++GTEM+ITK+GRRMFP +KV+V+GL+ K KYILLMDIV ADD RY
Sbjct: 106 KVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRY 165
Query: 65 KFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILN 124
KF +++W V GKA+P MP R+Y+HPDSPATG WM + V+F KLKLTNN D G ILN
Sbjct: 166 KFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILN 225
Query: 125 SMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAK 184
SMHKYQPR HIV+A N+ + F T+VFPET FIAVT+YQN KITQLKI+NNPFAK
Sbjct: 226 SMHKYQPRFHIVRA--NDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAK 283
Query: 185 GFR 187
GFR
Sbjct: 284 GFR 286
>gi|117676399 T-box transcription factor TBX20 [Homo sapiens]
Length = 447
Score = 240 bits (613), Expect = 2e-63
Identities = 136/287 (47%), Positives = 180/287 (62%), Gaps = 24/287 (8%)
Query: 1 MEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPAD 60
M I L +ELW KFHE+GTEMIITK+GRRMFP+ +V +G++P+ KYI+LMDIVP D
Sbjct: 97 MAKIACSLETKELWDKFHELGTEMIITKSGRRMFPTIRVSFSGVDPEAKYIVLMDIVPVD 156
Query: 61 DHRYKFADNK--WSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPF 118
+ RY++A ++ W V GKA+P +P RLYVHPDSP TG ++Q+VSF+K+KLTNN LD
Sbjct: 157 NKRYRYAYHRSSWLVAGKADPPLPARLYVHPDSPFTGEQLLKQMVSFEKVKLTNNELDQH 216
Query: 119 GHIILNSMHKYQPRLHIVKADENNG--FGSKNTAFCTHVFPETAFIAVTSYQNHKITQLK 176
GHIILNSMHKYQPR+HI+K ++ K+ F T +FPET F AVT+YQN IT+LK
Sbjct: 217 GHIILNSMHKYQPRVHIIKKKDHTASLLNLKSEEFRTFIFPETVFTAVTAYQNQLITKLK 276
Query: 177 IENNPFAKGFRGSD---DMELHRM-SRMQSKEYPVVPRSTV--RQKVASNHSPFS-SESR 229
I++NPFAKGFR S D+E + S +Q Y P T + V + S + +
Sbjct: 277 IDSNPFAKGFRDSSRLTDIERESVESLIQKHSYARSPIRTYGGEEDVLGDESQTTPNRGS 336
Query: 230 ALSTSSNL-------------GSQYQCENGVSGPSQDLLPPPNPYPL 263
A +TS NL G Q+ G S + P P+P+
Sbjct: 337 AFTTSDNLSLSSWVSSSSSFPGFQHPQSLTALGTSTASIATPIPHPI 383
>gi|47419907 T-box 3 protein isoform 2 [Homo sapiens]
Length = 743
Score = 239 bits (611), Expect = 3e-63
Identities = 162/444 (36%), Positives = 223/444 (50%), Gaps = 57/444 (12%)
Query: 5 KVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRY 64
KV L +ELW +FH+ GTEM+ITK+GRRMFP +KV+ +GL+ K KYILLMDI+ ADD RY
Sbjct: 104 KVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRY 163
Query: 65 KFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFG----- 119
KF +++W V GKA+P MP R+Y+HPDSPATG WM ++V+F KLKLTNN D G
Sbjct: 164 KFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAF 223
Query: 120 ---------------HIILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAV 164
ILNSMHKYQPR HIV+A N+ + F T++FPET FIAV
Sbjct: 224 PSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRA--NDILKLPYSTFRTYLFPETEFIAV 281
Query: 165 TSYQNHKITQLKIENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPF 224
T+YQN KITQLKI+NNPFAKGFR + + + ++ + V ++ S+ S
Sbjct: 282 TAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLTLQSMRVFDERHKKENGTSDES-- 339
Query: 225 SSESRALSTSSNLGSQYQCENGVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTT 284
SSE A + + S G S +DL P E + + + STT
Sbjct: 340 SSEQAAFNCFAQASSPAASTVGTSN-LKDLCPSEGESDAEAESKEEHGPEACDAAKISTT 398
Query: 285 --DHPYKKPYMETSPSEEDSFYRSSYPQQQGLGASYRTESAQRQACMYASS--------- 333
+ P + + SP+ + + + P+ G +S A + +S+
Sbjct: 399 TSEEPCRD---KGSPAVKAHLFAAERPRDSGRLDKASPDSRHSPATISSSTRGLGAEERR 455
Query: 334 APPSEPVPSLEDISCNTWPSMPSYSSCTVTTVQPMDRLPYQHFSAHFTSGPL-----VPR 388
+P E + P +++ TV T +AH GPL P
Sbjct: 456 SPVREGTAPAKVEEARALPGKEAFAPLTVQT---------DAAAAHLAQGPLPGLGFAPG 506
Query: 389 LAGMANHGSPQLGEGMFQHQTSVA 412
LAG G +F H + A
Sbjct: 507 LAGQQFFN----GHPLFLHPSQFA 526
>gi|5174711 T-box 1 isoform B [Homo sapiens]
Length = 372
Score = 239 bits (611), Expect = 3e-63
Identities = 126/241 (52%), Positives = 165/241 (68%), Gaps = 10/241 (4%)
Query: 3 GIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDH 62
G+ V L + LW +F+++GTEMI+TKAGRRMFP+++VK+ G++P Y+LLMD VP DD
Sbjct: 109 GVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDK 168
Query: 63 RYKFA--DNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH 120
RY++A + W V GKA+PA PGR++ HPDSPA GA WM+Q+VSF KLKLTNN LD GH
Sbjct: 169 RYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGH 228
Query: 121 IILNSMHKYQPRLHIVKAD---ENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKI 177
IILNSMH+YQPR H+V D ++ + +N F T VF ET F AVT+YQNH+ITQLKI
Sbjct: 229 IILNSMHRYQPRFHVVYVDPRKDSEKYAEEN--FKTFVFEETRFTAVTAYQNHRITQLKI 286
Query: 178 ENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPR-STVRQKVASNHSPFSSESRALSTSSN 236
+NPFAKGFR D + R R + P++ + R VAS P +E ++ S
Sbjct: 287 ASNPFAKGFRDCDPEDWPRNHRPGA--LPLMSAFARSRNPVASPTQPSGTEKGLVTEGSG 344
Query: 237 L 237
L
Sbjct: 345 L 345
>gi|18104952 T-box 1 isoform C [Homo sapiens]
Length = 495
Score = 238 bits (607), Expect = 9e-63
Identities = 125/234 (53%), Positives = 162/234 (69%), Gaps = 10/234 (4%)
Query: 3 GIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDH 62
G+ V L + LW +F+++GTEMI+TKAGRRMFP+++VK+ G++P Y+LLMD VP DD
Sbjct: 109 GVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDK 168
Query: 63 RYKFA--DNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH 120
RY++A + W V GKA+PA PGR++ HPDSPA GA WM+Q+VSF KLKLTNN LD GH
Sbjct: 169 RYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGH 228
Query: 121 IILNSMHKYQPRLHIVKAD---ENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKI 177
IILNSMH+YQPR H+V D ++ + +N F T VF ET F AVT+YQNH+ITQLKI
Sbjct: 229 IILNSMHRYQPRFHVVYVDPRKDSEKYAEEN--FKTFVFEETRFTAVTAYQNHRITQLKI 286
Query: 178 ENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPR-STVRQKVASNHSPFSSESRA 230
+NPFAKGFR D + R R + P++ + R VAS P +E A
Sbjct: 287 ASNPFAKGFRDCDPEDWPRNHRPGA--LPLMSAFARSRNPVASPTQPSGTEKDA 338
>gi|18104950 T-box 1 isoform A [Homo sapiens]
Length = 398
Score = 238 bits (606), Expect = 1e-62
Identities = 117/202 (57%), Positives = 149/202 (73%), Gaps = 7/202 (3%)
Query: 3 GIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDH 62
G+ V L + LW +F+++GTEMI+TKAGRRMFP+++VK+ G++P Y+LLMD VP DD
Sbjct: 109 GVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDK 168
Query: 63 RYKFA--DNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH 120
RY++A + W V GKA+PA PGR++ HPDSPA GA WM+Q+VSF KLKLTNN LD GH
Sbjct: 169 RYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGH 228
Query: 121 IILNSMHKYQPRLHIVKAD---ENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKI 177
IILNSMH+YQPR H+V D ++ + +N F T VF ET F AVT+YQNH+ITQLKI
Sbjct: 229 IILNSMHRYQPRFHVVYVDPRKDSEKYAEEN--FKTFVFEETRFTAVTAYQNHRITQLKI 286
Query: 178 ENNPFAKGFRGSDDMELHRMSR 199
+NPFAKGFR D + R R
Sbjct: 287 ASNPFAKGFRDCDPEDWPRNHR 308
>gi|18201900 T-box 6 [Homo sapiens]
Length = 436
Score = 236 bits (602), Expect = 3e-62
Identities = 110/189 (58%), Positives = 145/189 (76%), Gaps = 6/189 (3%)
Query: 1 MEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPAD 60
+ G+ + L RELW +F VGTEMIITKAGRRMFP+ +V VTGL+P+ +Y+ L+D++P D
Sbjct: 88 LPGVSLSLENRELWKEFSSVGTEMIITKAGRRMFPACRVSVTGLDPEARYLFLLDVIPVD 147
Query: 61 DHRYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH 120
RY++ +W +GKAEP +P R+Y+HPDSPATGAHWMRQ VSF ++KLTN+ LDP GH
Sbjct: 148 GARYRWQGRRWEPSGKAEPRLPDRVYIHPDSPATGAHWMRQPVSFHRVKLTNSTLDPHGH 207
Query: 121 IILNSMHKYQPRLHIVKADE--NNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIE 178
+IL+SMHKYQPR+H+V+A + + +G + FPET FI+VT+YQN +ITQLKI
Sbjct: 208 LILHSMHKYQPRIHLVRAAQLCSQHWG----GMASFRFPETTFISVTAYQNPQITQLKIA 263
Query: 179 NNPFAKGFR 187
NPFAKGFR
Sbjct: 264 ANPFAKGFR 272
>gi|32567784 T-box 10 [Homo sapiens]
Length = 385
Score = 231 bits (589), Expect = 1e-60
Identities = 128/275 (46%), Positives = 167/275 (60%), Gaps = 22/275 (8%)
Query: 4 IKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHR 63
+ V L + LW +F+++GTEMI+TKAGRRMFP ++VK+ G++ Y LLMD +P DD R
Sbjct: 65 VTVQLEMKPLWEEFNQLGTEMIVTKAGRRMFPPFQVKILGMDSLADYALLMDFIPLDDKR 124
Query: 64 YKFA--DNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHI 121
Y++A + W V GKA+PA PGR++ HPDSPA GA WMRQ+VSF KLKLTNN LD GHI
Sbjct: 125 YRYAFHSSAWLVAGKADPATPGRVHFHPDSPAKGAQWMRQIVSFDKLKLTNNLLDDNGHI 184
Query: 122 ILNSMHKYQPRLHIVKAD---ENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIE 178
ILNSMH+YQPR H+V D ++ + +N F + +F ET F AVT+YQNH+ITQLKI
Sbjct: 185 ILNSMHRYQPRFHVVFVDPRKDSERYAQEN--FKSFIFTETQFTAVTAYQNHRITQLKIA 242
Query: 179 NNPFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLG 238
+NPFAKGFR SD +PV PR + A +HS S +T
Sbjct: 243 SNPFAKGFRESD-----------LDSWPVAPRPLL-SVPARSHSSLSPCVLKGATDREKD 290
Query: 239 SQYQCENGVSGPS---QDLLPPPNPYPLPQEHSQI 270
+ P+ LLPPP P + +
Sbjct: 291 PNKASASTSKTPAWLHHQLLPPPEVLLAPATYRPV 325
>gi|55770860 T-box 15 [Homo sapiens]
Length = 496
Score = 226 bits (575), Expect = 4e-59
Identities = 139/354 (39%), Positives = 191/354 (53%), Gaps = 21/354 (5%)
Query: 1 MEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPAD 60
ME I+V L +LW +FH++GTEMIITKAGRRMFP+ +VK+TGL+P +Y + MDIVP D
Sbjct: 4 MEEIQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPHQQYYIAMDIVPVD 63
Query: 61 DHRYKFA--DNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPF 118
+ RY++ +KW V G A+ +P R+Y+HPDS A+G WMRQ+VSF KLKLTNN LD
Sbjct: 64 NKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQ 123
Query: 119 GHIILNSMHKYQPRLHIVKADENNGFGSK-----NTAFCTHVFPETAFIAVTSYQNHKIT 173
GHIIL+SMHKYQPR+H+++ D ++ T FPET F VT+YQN +IT
Sbjct: 124 GHIILHSMHKYQPRVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPETVFTTVTAYQNQQIT 183
Query: 174 QLKIENNPFAKGFRGSDDMELHRMSRMQSKEY---PVVPRS----TVRQKVASNHSPFSS 226
+LKI+ NPFAKGFR S + M++ + PV + T QK + S
Sbjct: 184 RLKIDRNPFAKGFRDSGRNRTGLEAIMETYAFWRPPVRTLTFEDFTTMQKQQGGSTGTSP 243
Query: 227 ESRALSTSSNLGSQYQCENGVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDH 286
+ + T S S + S P+ L PN + + SQ+ + C+ ++
Sbjct: 244 TTSSTGTPSPSASSHLLSPSCSPPTFHL--APNTFNVGCRESQLCNLNLSDYPPCARSNM 301
Query: 287 PYKKPYMETSPSEEDSFYRSSYPQQQGLGASYRTESAQRQACMYAS-SAPPSEP 339
+ Y P DS Y T QR + + PPS P
Sbjct: 302 AALQSY----PGLSDSGYNRLQSGTTSATQPSETFMPQRTPSLISGIPTPPSLP 351
>gi|122937456 T-box 18 [Homo sapiens]
Length = 607
Score = 223 bits (568), Expect = 3e-58
Identities = 109/195 (55%), Positives = 140/195 (71%), Gaps = 13/195 (6%)
Query: 5 KVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRY 64
+V L ELW +FHE+GTEMIITKAGRRMFP+ +VK++GL+P +Y + MDIVP D+ RY
Sbjct: 140 RVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLDPHQQYYIAMDIVPVDNKRY 199
Query: 65 KFA--DNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHII 122
++ +KW V G A+ +P R+Y+HPDSPA+G WMRQ++SF KLKLTNN LD GHII
Sbjct: 200 RYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVISFDKLKLTNNELDDQGHII 259
Query: 123 LNSMHKYQPRLHIVKADENNGF--------GSKNTAFCTHVFPETAFIAVTSYQNHKITQ 174
L+SMHKYQPR+H+++ D + G AF FPET F VT+YQN +IT+
Sbjct: 260 LHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGVKAFS---FPETVFTTVTAYQNQQITR 316
Query: 175 LKIENNPFAKGFRGS 189
LKI+ NPFAKGFR S
Sbjct: 317 LKIDRNPFAKGFRDS 331
>gi|4507339 transcription factor T [Homo sapiens]
Length = 435
Score = 209 bits (533), Expect = 3e-54
Identities = 135/381 (35%), Positives = 187/381 (49%), Gaps = 34/381 (8%)
Query: 4 IKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHR 63
++V L E ELWL+F E+ EMI+TK GRRMFP KV V+GL+P Y L+D V AD+HR
Sbjct: 42 LRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHR 101
Query: 64 YKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIIL 123
+K+ + +W GK EP P +Y+HPDSP GAHWM+ VSF K+KLTN L+ G I+L
Sbjct: 102 WKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNK-LNGGGQIML 160
Query: 124 NSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFA 183
NS+HKY+PR+HIV+ G +H FPET FIAVT+YQN +IT LKI+ NPFA
Sbjct: 161 NSLHKYEPRIHIVRV------GGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYNPFA 214
Query: 184 KGFRGSDDMELHR--MSRMQSKEYP-------VVPRSTVRQKVASNHSPFSSESRALSTS 234
K F + + H+ M + P ++P ++ A+ H F ALS
Sbjct: 215 KAFLDAKERSDHKEMMEEPGDSQQPGYSQWGWLLPGTSTLCPPANPHPQFGG---ALS-- 269
Query: 235 SNLGSQYQCENGVSGPSQDLLPPPNPY------PLPQEHSQIYHCTKRKEEECSTTDHPY 288
L S + C+ + S P P+PY P ++S + + S+ P
Sbjct: 270 --LPSTHSCDRYPTLRSHRSSPYPSPYAHRNNSPTYSDNSPACLSMLQSHDNWSSLGMPA 327
Query: 289 KKPYMETSPSEEDSFYRSSYPQQQGLGASYRTESAQRQACMYASSA-----PPSEPVPSL 343
+ S + S YP + T +Q A A P+ P
Sbjct: 328 HPSMLPVSHNASPPTSSSQYPSLWSVSNGAVTPGSQAAAVSNGLGAQFFRGSPAHYTPLT 387
Query: 344 EDISCNTWPSMPSYSSCTVTT 364
+S + P Y T
Sbjct: 388 HPVSAPSSSGSPLYEGAAAAT 408
>gi|122937388 MAX gene associated [Homo sapiens]
Length = 3114
Score = 207 bits (528), Expect = 1e-53
Identities = 106/191 (55%), Positives = 133/191 (69%), Gaps = 11/191 (5%)
Query: 3 GIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDH 62
GI V L +W +F+ TEMI+TK GRRMFP + +TGL+ KYIL+MDI P D+H
Sbjct: 74 GITVTLDNNSMWNEFYHRSTEMILTKQGRRMFPYCRYWITGLDSNLKYILVMDISPVDNH 133
Query: 63 RYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHII 122
RYK+ W +GKAEP + GR+++HP+SP+TG +WM Q VSF KLKLTNN LD GHII
Sbjct: 134 RYKWNGRWWEPSGKAEPHVLGRVFIHPESPSTGHYWMHQPVSFYKLKLTNNTLDQEGHII 193
Query: 123 LNSMHKYQPRLHIVKAD------ENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLK 176
L+SMH+Y PRLH+V A+ + NG G T FP+T F AVT+YQN +ITQLK
Sbjct: 194 LHSMHRYLPRLHLVPAEKAVEVIQLNGPGVH-----TFTFPQTEFFAVTAYQNIQITQLK 248
Query: 177 IENNPFAKGFR 187
I+ NPFAKGFR
Sbjct: 249 IDYNPFAKGFR 259
>gi|7019549 T-box 21 [Homo sapiens]
Length = 535
Score = 200 bits (509), Expect = 2e-51
Identities = 129/322 (40%), Positives = 171/322 (53%), Gaps = 37/322 (11%)
Query: 4 IKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHR 63
++V L+ LW KF++ TEMIITK GRRMFP V GL P + Y + +D+V D H
Sbjct: 137 LRVALNNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQHH 196
Query: 64 YKFADNKWSVTGKAEPAMPG-RLYVHPDSPATGAHWMRQLVSFQKLKLTNN---HLDPFG 119
+++ KW GKAE +MPG RLYVHPDSP TGAHWMRQ VSF KLKLTNN +
Sbjct: 197 WRYQSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFGKLKLTNNKGASNNVTQ 256
Query: 120 HIILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHV--FPETAFIAVTSYQNHKITQLKI 177
I+L S+HKYQPRLHIV+ ++ + N A TH+ F ET FIAVT+YQN +ITQLKI
Sbjct: 257 MIVLQSLHKYQPRLHIVEVNDGEPEAACN-ASNTHIFTFQETQFIAVTAYQNAEITQLKI 315
Query: 178 ENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNL 237
+NNPFAKGFR + M P P + ++SP L
Sbjct: 316 DNNPFAKGFREN----FESMYTSVDTSIPSPPGPNCQFLGGDHYSPL------------L 359
Query: 238 GSQYQCEN----GVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYM 293
+QY + + G ++D++P P++HS E K ++
Sbjct: 360 PNQYPVPSRFYPDLPGQAKDVVPQAYWLGAPRDHSY----------EAEFRAVSMKPAFL 409
Query: 294 ETSPSEEDSFYRSSYPQQQGLG 315
++P S+YR G G
Sbjct: 410 PSAPGPTMSYYRGQEVLAPGAG 431
>gi|158187509 T-box 22 isoform 1 [Homo sapiens]
Length = 520
Score = 198 bits (503), Expect = 1e-50
Identities = 113/261 (43%), Positives = 154/261 (59%), Gaps = 18/261 (6%)
Query: 4 IKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHR 63
I++ L ELW +FH++GTEMIITKAGRRMFPS +VKV GL+P +Y + +D+VP D R
Sbjct: 92 IQMELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVDSKR 151
Query: 64 YKFA--DNKWSVTGKAEP-AMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH 120
Y++ ++W V G + + R YVHPDSP +G WMRQ++SF ++KLTNN +D GH
Sbjct: 152 YRYVYHSSQWMVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKGH 211
Query: 121 IILNSMHKYQPRLHIVK----ADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLK 176
IIL SMHKY+PR+H+++ D + T F ET F VT+YQN +IT+LK
Sbjct: 212 IILQSMHKYKPRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQITKLK 271
Query: 177 IENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSN 236
IE NPFAKGFR D + + YP P T+ K F +++++ S+ S
Sbjct: 272 IERNPFAKGFR--DTGRNRGVLDGLLETYPWRPSFTLDFKT------FGADTQSGSSGS- 322
Query: 237 LGSQYQCENGVSGPSQDLLPP 257
S G P LL P
Sbjct: 323 --SPVTSSGGAPSPLNSLLSP 341
>gi|18375603 T-box 22 isoform 1 [Homo sapiens]
Length = 520
Score = 198 bits (503), Expect = 1e-50
Identities = 113/261 (43%), Positives = 154/261 (59%), Gaps = 18/261 (6%)
Query: 4 IKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHR 63
I++ L ELW +FH++GTEMIITKAGRRMFPS +VKV GL+P +Y + +D+VP D R
Sbjct: 92 IQMELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVDSKR 151
Query: 64 YKFA--DNKWSVTGKAEP-AMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH 120
Y++ ++W V G + + R YVHPDSP +G WMRQ++SF ++KLTNN +D GH
Sbjct: 152 YRYVYHSSQWMVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKGH 211
Query: 121 IILNSMHKYQPRLHIVK----ADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLK 176
IIL SMHKY+PR+H+++ D + T F ET F VT+YQN +IT+LK
Sbjct: 212 IILQSMHKYKPRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQITKLK 271
Query: 177 IENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSN 236
IE NPFAKGFR D + + YP P T+ K F +++++ S+ S
Sbjct: 272 IERNPFAKGFR--DTGRNRGVLDGLLETYPWRPSFTLDFKT------FGADTQSGSSGS- 322
Query: 237 LGSQYQCENGVSGPSQDLLPP 257
S G P LL P
Sbjct: 323 --SPVTSSGGAPSPLNSLLSP 341
>gi|5730081 T-box, brain, 1 [Homo sapiens]
Length = 682
Score = 196 bits (498), Expect = 4e-50
Identities = 102/195 (52%), Positives = 135/195 (69%), Gaps = 11/195 (5%)
Query: 5 KVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRY 64
+V+L R LWLKFH TEMIITK GRRMFP ++GL+P Y + +D++ AD + +
Sbjct: 205 QVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNISGLDPTAHYNIFVDVILADPNHW 264
Query: 65 KFADNKWSVTGKAEPAMPG-RLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH--- 120
+F KW GKA+ + G R+Y+HPDSP TGAHWMRQ +SF KLKLTNN +
Sbjct: 265 RFQGGKWVPCGKADTNVQGNRVYMHPDSPNTGAHWMRQEISFGKLKLTNNKGASNNNGQM 324
Query: 121 IILNSMHKYQPRLHIVKADENNGFGSKNTA----FCTHVFPETAFIAVTSYQNHKITQLK 176
++L S+HKYQPRLH+V+ +E+ G+++T+ T FPET FIAVT+YQN ITQLK
Sbjct: 325 VVLQSLHKYQPRLHVVEVNED---GTEDTSQPGRVQTFTFPETQFIAVTAYQNTDITQLK 381
Query: 177 IENNPFAKGFRGSDD 191
I++NPFAKGFR + D
Sbjct: 382 IDHNPFAKGFRDNYD 396
>gi|4827024 T-box 19 [Homo sapiens]
Length = 448
Score = 194 bits (493), Expect = 1e-49
Identities = 152/446 (34%), Positives = 204/446 (45%), Gaps = 57/446 (12%)
Query: 4 IKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHR 63
+++ L + LW +F EV EMI+TK GRRMFP K+ VTGL+P Y LL+D VP D HR
Sbjct: 41 LQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHR 100
Query: 64 YKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIIL 123
+K+ + +W GK E + +Y+HPDSP GAHWM+ +SF K+KLTN L+ G I+L
Sbjct: 101 WKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNK-LNGGGQIML 159
Query: 124 NSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFA 183
NS+HKY+P++HIV+ GS + FPET FIAVT+YQN +IT LKI+ NPFA
Sbjct: 160 NSLHKYEPQVHIVRV------GSAHRMVTNCSFPETQFIAVTAYQNEEITALKIKYNPFA 213
Query: 184 KGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQC 243
K F L R ++ P SES+ ++ S G +
Sbjct: 214 KAF-------LDAKERNHLRDVPEA----------------ISESQHVTYSHLGGWIFSN 250
Query: 244 ENGV--SGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSEED 301
+GV +G S P P P P H H + + PY YM + S
Sbjct: 251 PDGVCTAGNSNYQYAAPLPLPAPHTHHGCEHYSGLRGHR----QAPYPSAYMHRNHSPSV 306
Query: 302 SFYRSSYPQQQGLGA--SYRTESAQRQACMYA------SSAPPSEPVPSLEDISCNT-WP 352
+ SS Q S+ + S+ A + + P P P L IS P
Sbjct: 307 NLIESSSNNLQVFSGPDSWTSLSSTPHASILSVPHTNGPINPGPSPYPCLWTISNGAGGP 366
Query: 353 SMPSYSSCTVTTVQPMDRLPYQHFSAHFTSGPLV-----PRLAGMANHGSPQLGEGMFQH 407
S P V + + TS P V P AG+ G P L
Sbjct: 367 SGPG------PEVHASTPGAFLLGNPAVTSPPSVLSTQAPTSAGVEVLGEPSLTSIAVST 420
Query: 408 QTSVAHQPVVRQCGPQT-GLQSPGTL 432
T+VA P GP G SP +L
Sbjct: 421 WTAVASHPFAGWGGPGAGGHHSPSSL 446
>gi|22538470 eomesodermin [Homo sapiens]
Length = 686
Score = 192 bits (487), Expect = 7e-49
Identities = 127/327 (38%), Positives = 175/327 (53%), Gaps = 18/327 (5%)
Query: 6 VFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYK 65
V+L R LWLKFH TEMIITK GRRMFP + GLNP Y + +++V AD + ++
Sbjct: 269 VYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWR 328
Query: 66 FADNKWSVTGKAEPAMPG-RLYVHPDSPATGAHWMRQLVSFQKLKLTNN---HLDPFGHI 121
F KW GKA+ M G ++YVHP+SP TG+HWMRQ +SF KLKLTNN + + I
Sbjct: 329 FQGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMI 388
Query: 122 ILNSMHKYQPRLHIVKADENNGFGSKN--TAFCTHVFPETAFIAVTSYQNHKITQLKIEN 179
+L S+HKYQPRLHIV+ E +G N + T F ET FIAVT+YQN ITQLKI++
Sbjct: 389 VLQSLHKYQPRLHIVEVTE-DGVEDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKIDH 447
Query: 180 NPFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGS 239
NPFAKGFR + D + + P V + + + R + ++ L S
Sbjct: 448 NPFAKGFRDNYDSSHQIVPGGRYGVQSFFPEPFVN---TLPQARYYNGERTVPQTNGLLS 504
Query: 240 QYQCENGVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSE 299
Q E + P + L+ P+ Q + + + E S+T PY + S
Sbjct: 505 PQQSEEVANPPQRWLVT-----PVQQPGTNKLDISSYESEYTSSTLLPYGIKSLPLQTSH 559
Query: 300 EDSFYRS-SYPQQQGLG--ASYRTESA 323
+Y ++P G G SY+ + A
Sbjct: 560 ALGYYPDPTFPAMAGWGGRGSYQRKMA 586
>gi|158187511 T-box 22 isoform 2 [Homo sapiens]
Length = 400
Score = 159 bits (401), Expect = 7e-39
Identities = 94/232 (40%), Positives = 130/232 (56%), Gaps = 18/232 (7%)
Query: 33 MFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFA--DNKWSVTGKAEP-AMPGRLYVHP 89
MFPS +VKV GL+P +Y + +D+VP D RY++ ++W V G + + R YVHP
Sbjct: 1 MFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHP 60
Query: 90 DSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVK----ADENNGFG 145
DSP +G WMRQ++SF ++KLTNN +D GHIIL SMHKY+PR+H+++ D +
Sbjct: 61 DSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQS 120
Query: 146 SKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDMELHRMSRMQSKEY 205
T F ET F VT+YQN +IT+LKIE NPFAKGFR D + + Y
Sbjct: 121 LPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFR--DTGRNRGVLDGLLETY 178
Query: 206 PVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSGPSQDLLPP 257
P P T+ K F +++++ S+ S S G P LL P
Sbjct: 179 PWRPSFTLDFKT------FGADTQSGSSGS---SPVTSSGGAPSPLNSLLSP 221
>gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo
sapiens]
Length = 1562
Score = 42.7 bits (99), Expect = 7e-04
Identities = 50/219 (22%), Positives = 83/219 (37%), Gaps = 25/219 (11%)
Query: 177 IENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSN 236
+E N K +R +D + P +P + + + ++S R STS +
Sbjct: 1028 VEQNKLNKDYRANDTVP------------PTIPYNQSYDQ--NTGGSYNSSDRGSSTSGS 1073
Query: 237 LGSQYQCENGVSGPSQ------DLLPPPNPYPLPQEHSQIYHCT-KRKEEECSTTDHPYK 289
G + P Q DLLPPP +P P +S+ Y+ + ++ P
Sbjct: 1074 QGHKKGARTP-KVPKQGGMNWADLLPPPPAHPPPHSNSEEYNISVDESYDQEMPCPVPPA 1132
Query: 290 KPYMETSPSEEDSFYRSSYPQQQGLGASYRTESAQRQACMYASSAPPSEPVPSLEDISCN 349
+ Y++ EE+ R P +G +S S Q+ + +P E P L+D
Sbjct: 1133 RTYLQQDELEEEEDERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEE 1192
Query: 350 T--WPSMPSYSSCTVTTVQPMDRLPYQHFSAHFTSGPLV 386
T P V+ P + H + + SGPLV
Sbjct: 1193 TGHMQHQPDRRRQPVSPPPPPRPISPPH-TYGYISGPLV 1230
>gi|239748171 PREDICTED: similar to roundabout 1 isoform 2 [Homo
sapiens]
Length = 1615
Score = 42.7 bits (99), Expect = 7e-04
Identities = 50/219 (22%), Positives = 83/219 (37%), Gaps = 25/219 (11%)
Query: 177 IENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSN 236
+E N K +R +D + P +P + + + ++S R STS +
Sbjct: 1081 VEQNKLNKDYRANDTVP------------PTIPYNQSYDQ--NTGGSYNSSDRGSSTSGS 1126
Query: 237 LGSQYQCENGVSGPSQ------DLLPPPNPYPLPQEHSQIYHCT-KRKEEECSTTDHPYK 289
G + P Q DLLPPP +P P +S+ Y+ + ++ P
Sbjct: 1127 QGHKKGARTP-KVPKQGGMNWADLLPPPPAHPPPHSNSEEYNISVDESYDQEMPCPVPPA 1185
Query: 290 KPYMETSPSEEDSFYRSSYPQQQGLGASYRTESAQRQACMYASSAPPSEPVPSLEDISCN 349
+ Y++ EE+ R P +G +S S Q+ + +P E P L+D
Sbjct: 1186 RTYLQQDELEEEEDERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEE 1245
Query: 350 T--WPSMPSYSSCTVTTVQPMDRLPYQHFSAHFTSGPLV 386
T P V+ P + H + + SGPLV
Sbjct: 1246 TGHMQHQPDRRRQPVSPPPPPRPISPPH-TYGYISGPLV 1283
>gi|224994173 roundabout 1 isoform d [Homo sapiens]
Length = 1551
Score = 42.4 bits (98), Expect = 0.001
Identities = 50/219 (22%), Positives = 83/219 (37%), Gaps = 25/219 (11%)
Query: 177 IENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSN 236
+E N K +R +D + P +P + + + ++S R STS +
Sbjct: 1017 VEQNKLNKDYRANDTVP------------PTIPYNQSYDQ--NTGGSYNSSDRGSSTSGS 1062
Query: 237 LGSQYQCENGVSGPSQ------DLLPPPNPYPLPQEHSQIYHCT-KRKEEECSTTDHPYK 289
G + P Q DLLPPP +P P +S+ Y+ + ++ P
Sbjct: 1063 QGHKKGARTP-KVPKQGGMNWADLLPPPPAHPPPHSNSEEYNISVDESYDQEMPCPVPPA 1121
Query: 290 KPYMETSPSEEDSFYRSSYPQQQGLGASYRTESAQRQACMYASSAPPSEPVPSLEDISCN 349
+ Y++ EE+ R P +G +S S Q+ + +P E P L+D
Sbjct: 1122 RMYLQQDELEEEEDERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEE 1181
Query: 350 T--WPSMPSYSSCTVTTVQPMDRLPYQHFSAHFTSGPLV 386
T P V+ P + H + + SGPLV
Sbjct: 1182 TGHMQHQPDRRRQPVSPPPPPRPISPPH-TYGYISGPLV 1219
>gi|224994171 roundabout 1 isoform c [Homo sapiens]
Length = 1606
Score = 42.4 bits (98), Expect = 0.001
Identities = 50/219 (22%), Positives = 83/219 (37%), Gaps = 25/219 (11%)
Query: 177 IENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSN 236
+E N K +R +D + P +P + + + ++S R STS +
Sbjct: 1072 VEQNKLNKDYRANDTVP------------PTIPYNQSYDQ--NTGGSYNSSDRGSSTSGS 1117
Query: 237 LGSQYQCENGVSGPSQ------DLLPPPNPYPLPQEHSQIYHCT-KRKEEECSTTDHPYK 289
G + P Q DLLPPP +P P +S+ Y+ + ++ P
Sbjct: 1118 QGHKKGARTP-KVPKQGGMNWADLLPPPPAHPPPHSNSEEYNISVDESYDQEMPCPVPPA 1176
Query: 290 KPYMETSPSEEDSFYRSSYPQQQGLGASYRTESAQRQACMYASSAPPSEPVPSLEDISCN 349
+ Y++ EE+ R P +G +S S Q+ + +P E P L+D
Sbjct: 1177 RMYLQQDELEEEEDERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEE 1236
Query: 350 T--WPSMPSYSSCTVTTVQPMDRLPYQHFSAHFTSGPLV 386
T P V+ P + H + + SGPLV
Sbjct: 1237 TGHMQHQPDRRRQPVSPPPPPRPISPPH-TYGYISGPLV 1274
>gi|19743806 roundabout 1 isoform b [Homo sapiens]
Length = 1612
Score = 42.4 bits (98), Expect = 0.001
Identities = 50/219 (22%), Positives = 83/219 (37%), Gaps = 25/219 (11%)
Query: 177 IENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSN 236
+E N K +R +D + P +P + + + ++S R STS +
Sbjct: 1078 VEQNKLNKDYRANDTVP------------PTIPYNQSYDQ--NTGGSYNSSDRGSSTSGS 1123
Query: 237 LGSQYQCENGVSGPSQ------DLLPPPNPYPLPQEHSQIYHCT-KRKEEECSTTDHPYK 289
G + P Q DLLPPP +P P +S+ Y+ + ++ P
Sbjct: 1124 QGHKKGARTP-KVPKQGGMNWADLLPPPPAHPPPHSNSEEYNISVDESYDQEMPCPVPPA 1182
Query: 290 KPYMETSPSEEDSFYRSSYPQQQGLGASYRTESAQRQACMYASSAPPSEPVPSLEDISCN 349
+ Y++ EE+ R P +G +S S Q+ + +P E P L+D
Sbjct: 1183 RMYLQQDELEEEEDERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEE 1242
Query: 350 T--WPSMPSYSSCTVTTVQPMDRLPYQHFSAHFTSGPLV 386
T P V+ P + H + + SGPLV
Sbjct: 1243 TGHMQHQPDRRRQPVSPPPPPRPISPPH-TYGYISGPLV 1280
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.131 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,207,734
Number of Sequences: 37866
Number of extensions: 1094678
Number of successful extensions: 4267
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 86
Number of HSP's that attempted gapping in prelim test: 4087
Number of HSP's gapped (non-prelim): 217
length of query: 468
length of database: 18,247,518
effective HSP length: 106
effective length of query: 362
effective length of database: 14,233,722
effective search space: 5152607364
effective search space used: 5152607364
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.