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Search of human proteins with 18139549
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18139549 SET domain-containing protein 7 [Homo sapiens]
(366 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18139549 SET domain-containing protein 7 [Homo sapiens] 768 0.0
gi|149999376 MORN repeat containing 4 [Homo sapiens] 63 5e-10
gi|30520314 MORN repeat containing 4 [Homo sapiens] 63 5e-10
gi|13376267 MORN repeat containing 1 [Homo sapiens] 60 2e-09
gi|18254456 testis-specific gene A2 [Homo sapiens] 56 4e-08
gi|153792461 radial spoke head 10 homolog B2 [Homo sapiens] 55 1e-07
gi|157502187 radial spoke head 10 homolog B [Homo sapiens] 55 1e-07
gi|50355990 MORN repeat containing 3 [Homo sapiens] 47 2e-05
gi|75750529 ankyrin repeat and MYND domain containing 1 isoform ... 47 3e-05
gi|19923202 enhancer of zeste homolog 1 [Homo sapiens] 41 0.001
gi|224282170 MORN repeat containing 2 [Homo sapiens] 40 0.003
gi|4507321 suppressor of variegation 3-9 homolog 1 [Homo sapiens] 38 0.013
gi|23510384 enhancer of zeste 2 isoform b [Homo sapiens] 38 0.013
gi|21361095 enhancer of zeste 2 isoform a [Homo sapiens] 38 0.013
gi|40316935 alsin isoform 1 [Homo sapiens] 38 0.013
gi|75750531 ankyrin repeat and MYND domain containing 1 isoform ... 37 0.021
gi|21704283 junctophilin 3 [Homo sapiens] 36 0.048
gi|21704281 junctophilin 2 isoform 1 [Homo sapiens] 35 0.081
gi|223278407 MORN repeat containing 5 [Homo sapiens] 35 0.081
gi|225690502 junctophilin 4 [Homo sapiens] 35 0.14
gi|225690500 junctophilin 4 [Homo sapiens] 35 0.14
gi|21735575 junctophilin 1 [Homo sapiens] 34 0.18
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 33 0.40
gi|55741677 SET domain containing 1A [Homo sapiens] 33 0.53
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s... 33 0.53
gi|238624099 SET domain, bifurcated 2 isoform b [Homo sapiens] 32 0.90
gi|238624095 SET domain, bifurcated 2 isoform a [Homo sapiens] 32 0.90
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 32 0.90
gi|31543169 suppressor of variegation 4-20 homolog 2 [Homo sapiens] 32 0.90
gi|33359215 ALS2 C-terminal like isoform 1 [Homo sapiens] 31 1.5
>gi|18139549 SET domain-containing protein 7 [Homo sapiens]
Length = 366
Score = 768 bits (1982), Expect = 0.0
Identities = 366/366 (100%), Positives = 366/366 (100%)
Query: 1 MDSDDEMVEEAVEGHLDDDGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLE 60
MDSDDEMVEEAVEGHLDDDGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLE
Sbjct: 1 MDSDDEMVEEAVEGHLDDDGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLE 60
Query: 61 GYYVDDALQGQGVYTYEDGGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCW 120
GYYVDDALQGQGVYTYEDGGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCW
Sbjct: 61 GYYVDDALQGQGVYTYEDGGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCW 120
Query: 121 IYYPDGGSLVGEVNEDGEMTGEKIAYVYPDERTALYGKFIDGEMIEGKLATLMSTEEGRP 180
IYYPDGGSLVGEVNEDGEMTGEKIAYVYPDERTALYGKFIDGEMIEGKLATLMSTEEGRP
Sbjct: 121 IYYPDGGSLVGEVNEDGEMTGEKIAYVYPDERTALYGKFIDGEMIEGKLATLMSTEEGRP 180
Query: 181 HFELMPGNSVYHFDKSTSSCISTNALLPDPYESERVYVAESLISSAGEGLFSKVAVGPNT 240
HFELMPGNSVYHFDKSTSSCISTNALLPDPYESERVYVAESLISSAGEGLFSKVAVGPNT
Sbjct: 181 HFELMPGNSVYHFDKSTSSCISTNALLPDPYESERVYVAESLISSAGEGLFSKVAVGPNT 240
Query: 241 VMSFYNGVRITHQEVDSRDWALNGNTLSLDEETVIDVPEPYNHVSKYCASLGHKANHSFT 300
VMSFYNGVRITHQEVDSRDWALNGNTLSLDEETVIDVPEPYNHVSKYCASLGHKANHSFT
Sbjct: 241 VMSFYNGVRITHQEVDSRDWALNGNTLSLDEETVIDVPEPYNHVSKYCASLGHKANHSFT 300
Query: 301 PNCIYDMFVHPRFGPIKCIRTLRAVEADEELTVAYGYDHSPPGKSGPEAPEWYQVELKAF 360
PNCIYDMFVHPRFGPIKCIRTLRAVEADEELTVAYGYDHSPPGKSGPEAPEWYQVELKAF
Sbjct: 301 PNCIYDMFVHPRFGPIKCIRTLRAVEADEELTVAYGYDHSPPGKSGPEAPEWYQVELKAF 360
Query: 361 QATQQK 366
QATQQK
Sbjct: 361 QATQQK 366
>gi|149999376 MORN repeat containing 4 [Homo sapiens]
Length = 146
Score = 62.8 bits (151), Expect = 5e-10
Identities = 32/100 (32%), Positives = 52/100 (52%), Gaps = 5/100 (5%)
Query: 29 TYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYEDGGVLQGTYVD 88
TYSS + + G + G ++G G+ F DG T G++ + G GV T+ DG +G +
Sbjct: 9 TYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQ 68
Query: 89 GELNGPAQ--EYDTDGRLIFKGQYKDNIRHGVCWIYYPDG 126
G+ NG YD + F+G++K+ G + +PDG
Sbjct: 69 GKFNGVGVFIRYD---NMTFEGEFKNGRVDGFGLLTFPDG 105
Score = 53.9 bits (128), Expect = 2e-07
Identities = 26/66 (39%), Positives = 39/66 (59%), Gaps = 1/66 (1%)
Query: 14 GHLDDDGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGV 73
GH ++ GL +GF +T+S R+EG F G+ NG G F +D T EG + + + G G+
Sbjct: 41 GHFEN-GLFNGFGVLTFSDGSRYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGL 99
Query: 74 YTYEDG 79
T+ DG
Sbjct: 100 LTFPDG 105
Score = 46.6 bits (109), Expect = 4e-05
Identities = 23/75 (30%), Positives = 37/75 (49%)
Query: 19 DGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYED 78
+G HGF + ++ + G+F +G NG G F DGS EG + G GV+ D
Sbjct: 22 EGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFNGVGVFIRYD 81
Query: 79 GGVLQGTYVDGELNG 93
+G + +G ++G
Sbjct: 82 NMTFEGEFKNGRVDG 96
Score = 30.0 bits (66), Expect = 3.4
Identities = 18/63 (28%), Positives = 31/63 (49%), Gaps = 8/63 (12%)
Query: 106 FKGQYKDNIRHGVCWIYYPDGGSLVGEVNEDGEMTGEKIAYVYPDERTALYGKFIDGEMI 165
++G++K+ RHG + + DGG+ +G E+G G + T G +GE
Sbjct: 16 YRGEWKEGRRHGFGQLMFADGGTYLGHF-ENGLFNGFGVL-------TFSDGSRYEGEFA 67
Query: 166 EGK 168
+GK
Sbjct: 68 QGK 70
>gi|30520314 MORN repeat containing 4 [Homo sapiens]
Length = 146
Score = 62.8 bits (151), Expect = 5e-10
Identities = 32/100 (32%), Positives = 52/100 (52%), Gaps = 5/100 (5%)
Query: 29 TYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYEDGGVLQGTYVD 88
TYSS + + G + G ++G G+ F DG T G++ + G GV T+ DG +G +
Sbjct: 9 TYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQ 68
Query: 89 GELNGPAQ--EYDTDGRLIFKGQYKDNIRHGVCWIYYPDG 126
G+ NG YD + F+G++K+ G + +PDG
Sbjct: 69 GKFNGVGVFIRYD---NMTFEGEFKNGRVDGFGLLTFPDG 105
Score = 53.9 bits (128), Expect = 2e-07
Identities = 26/66 (39%), Positives = 39/66 (59%), Gaps = 1/66 (1%)
Query: 14 GHLDDDGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGV 73
GH ++ GL +GF +T+S R+EG F G+ NG G F +D T EG + + + G G+
Sbjct: 41 GHFEN-GLFNGFGVLTFSDGSRYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGL 99
Query: 74 YTYEDG 79
T+ DG
Sbjct: 100 LTFPDG 105
Score = 46.6 bits (109), Expect = 4e-05
Identities = 23/75 (30%), Positives = 37/75 (49%)
Query: 19 DGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYED 78
+G HGF + ++ + G+F +G NG G F DGS EG + G GV+ D
Sbjct: 22 EGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFNGVGVFIRYD 81
Query: 79 GGVLQGTYVDGELNG 93
+G + +G ++G
Sbjct: 82 NMTFEGEFKNGRVDG 96
Score = 30.0 bits (66), Expect = 3.4
Identities = 18/63 (28%), Positives = 31/63 (49%), Gaps = 8/63 (12%)
Query: 106 FKGQYKDNIRHGVCWIYYPDGGSLVGEVNEDGEMTGEKIAYVYPDERTALYGKFIDGEMI 165
++G++K+ RHG + + DGG+ +G E+G G + T G +GE
Sbjct: 16 YRGEWKEGRRHGFGQLMFADGGTYLGHF-ENGLFNGFGVL-------TFSDGSRYEGEFA 67
Query: 166 EGK 168
+GK
Sbjct: 68 QGK 70
>gi|13376267 MORN repeat containing 1 [Homo sapiens]
Length = 497
Score = 60.5 bits (145), Expect = 2e-09
Identities = 36/114 (31%), Positives = 54/114 (47%), Gaps = 2/114 (1%)
Query: 20 GLPHGFCTVTYSSTDRFEGNFVHGEKNGRG-KFFFFDGSTLEGYYVDDALQGQGVYTYED 78
G HG + + +EG FV GE G G + + + G T G +V QG GV Y+
Sbjct: 46 GRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDTFSGQFVLGEPQGYGVMEYKA 105
Query: 79 GGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCWIYYPDGGSLVGE 132
GG +G G G D DG+ +++G + DN RHG + + +G G+
Sbjct: 106 GGCYEGEVSHGMREGHGFLVDRDGQ-VYQGSFHDNKRHGPGQMLFQNGDKYDGD 158
Score = 48.1 bits (113), Expect = 1e-05
Identities = 36/125 (28%), Positives = 53/125 (42%), Gaps = 6/125 (4%)
Query: 12 VEGHLDDDGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQ 71
V+G + +G H S D F G FV GE G G + G EG +G
Sbjct: 67 VDGEITGEGRRHWAW-----SGDTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGH 121
Query: 72 GVYTYEDGGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCWIYYPDGGSLVG 131
G DG V QG++ D + +GP Q +G + G + + R G + DG + G
Sbjct: 122 GFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDK-YDGDWVRDRRQGHGVLRCADGSTYKG 180
Query: 132 EVNED 136
+ + D
Sbjct: 181 QWHSD 185
Score = 41.6 bits (96), Expect = 0.001
Identities = 33/113 (29%), Positives = 47/113 (41%), Gaps = 24/113 (21%)
Query: 23 HGFCTVTY-SSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYEDGGV 81
+G+ Y +S R+EG + G K+G GK F DGS YY
Sbjct: 25 NGYGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGS----YY------------------ 62
Query: 82 LQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCWIYYPDGGSLVGEVN 134
+G +VDGE+ G + + F GQ+ G + Y GG GEV+
Sbjct: 63 -EGAFVDGEITGEGRRHWAWSGDTFSGQFVLGEPQGYGVMEYKAGGCYEGEVS 114
Score = 40.8 bits (94), Expect = 0.002
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
Query: 19 DGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYED 78
D HG + + + D+++G++V + G G DGST +G + D G G +
Sbjct: 138 DNKRHGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAHCS 197
Query: 79 GGVLQGTYVDGELNGPAQE 97
G G +++G PA++
Sbjct: 198 GVTYYGLWINGH---PAEQ 213
Score = 37.4 bits (85), Expect = 0.021
Identities = 17/58 (29%), Positives = 30/58 (51%)
Query: 36 FEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYEDGGVLQGTYVDGELNG 93
++G+F +++G G+ F +G +G +V D QG GV DG +G + +G
Sbjct: 132 YQGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSG 189
>gi|18254456 testis-specific gene A2 [Homo sapiens]
Length = 309
Score = 56.2 bits (134), Expect = 4e-08
Identities = 39/134 (29%), Positives = 65/134 (48%), Gaps = 3/134 (2%)
Query: 13 EGHLDDDGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQG 72
EG ++ G HG + D +EG++ G+++G+G + F +G+ G YV + GQG
Sbjct: 21 EGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQG 80
Query: 73 VYTYEDGGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGV-CWIYYPDGGSLVG 131
+ Y DG +G + + +G Y + + G++ + RHG ++Y G VG
Sbjct: 81 TFIYPDGSRYEGEWANDLRHGHGVYYYINND-TYTGEWFAHQRHGQGTYLYAETGSKYVG 139
Query: 132 E-VNEDGEMTGEKI 144
VN E T E I
Sbjct: 140 TWVNGQQEGTAELI 153
>gi|153792461 radial spoke head 10 homolog B2 [Homo sapiens]
Length = 870
Score = 54.7 bits (130), Expect = 1e-07
Identities = 35/123 (28%), Positives = 57/123 (46%), Gaps = 1/123 (0%)
Query: 6 EMVEEAVEGHLDDDGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVD 65
+++ E+ EG GL G + + G F G +G+G + + DG EG +V
Sbjct: 80 KLIVESYEGE-KVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVK 138
Query: 66 DALQGQGVYTYEDGGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCWIYYPD 125
+ GVYT+ DG + +G V+G NG + + + G + + RHG IYY
Sbjct: 139 NVPMNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQ 198
Query: 126 GGS 128
G+
Sbjct: 199 EGT 201
Score = 50.1 bits (118), Expect = 3e-06
Identities = 25/84 (29%), Positives = 45/84 (53%), Gaps = 10/84 (11%)
Query: 20 GLPHGFCTVT----------YSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQ 69
G+ +GF T T Y + + G FV+G ++GRGKF++ G+ +G +V +
Sbjct: 258 GIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKH 317
Query: 70 GQGVYTYEDGGVLQGTYVDGELNG 93
G G T+++G V +G + + + G
Sbjct: 318 GMGRLTFKNGRVYEGAFSNDHIAG 341
Score = 34.7 bits (78), Expect = 0.14
Identities = 16/52 (30%), Positives = 28/52 (53%)
Query: 19 DGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQG 70
+G HG Y+S ++G +V +K+G G+ F +G EG + +D + G
Sbjct: 290 NGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAG 341
Score = 32.7 bits (73), Expect = 0.53
Identities = 34/131 (25%), Positives = 54/131 (41%), Gaps = 22/131 (16%)
Query: 19 DGLPHGFCTVTYSS--TDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQG---- 72
+G HG ++ Y+ T +EG++V K G G + G+ EG + D+ G+G
Sbjct: 185 NGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRW 244
Query: 73 VYTYEDGGVLQGTYVDGELNG-----------PAQEYDTDGRLIFKGQYKDNIRHGVCWI 121
+ T E+ G + G NG + +Y I G++ + RHG
Sbjct: 245 LTTNEE---YTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYI--GEFVNGYRHGRGKF 299
Query: 122 YYPDGGSLVGE 132
YY G GE
Sbjct: 300 YYASGAMYDGE 310
Score = 29.3 bits (64), Expect = 5.8
Identities = 22/107 (20%), Positives = 48/107 (44%), Gaps = 12/107 (11%)
Query: 18 DDGLPHGFCTVTYSST-DRFEGNFVHGEKNGRGKFFFFDGSTLE----------GYYVDD 66
+D + HG + + +T + + G + G +NG G +F G +V+
Sbjct: 232 EDNMRHGEGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNG 291
Query: 67 ALQGQGVYTYEDGGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDN 113
G+G + Y G + G +V + +G + +GR +++G + ++
Sbjct: 292 YRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGR-VYEGAFSND 337
>gi|157502187 radial spoke head 10 homolog B [Homo sapiens]
Length = 870
Score = 54.7 bits (130), Expect = 1e-07
Identities = 35/123 (28%), Positives = 57/123 (46%), Gaps = 1/123 (0%)
Query: 6 EMVEEAVEGHLDDDGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVD 65
+++ E+ EG GL G + + G F G +G+G + + DG EG +V
Sbjct: 80 KLIVESYEGE-KVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVK 138
Query: 66 DALQGQGVYTYEDGGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCWIYYPD 125
+ GVYT+ DG + +G V+G NG + + + G + + RHG IYY
Sbjct: 139 NVPMNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQ 198
Query: 126 GGS 128
G+
Sbjct: 199 EGT 201
Score = 50.1 bits (118), Expect = 3e-06
Identities = 25/84 (29%), Positives = 45/84 (53%), Gaps = 10/84 (11%)
Query: 20 GLPHGFCTVT----------YSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQ 69
G+ +GF T T Y + + G FV+G ++GRGKF++ G+ +G +V +
Sbjct: 258 GIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKH 317
Query: 70 GQGVYTYEDGGVLQGTYVDGELNG 93
G G T+++G V +G + + + G
Sbjct: 318 GMGRLTFKNGRVYEGAFSNDHIAG 341
Score = 34.7 bits (78), Expect = 0.14
Identities = 16/52 (30%), Positives = 28/52 (53%)
Query: 19 DGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQG 70
+G HG Y+S ++G +V +K+G G+ F +G EG + +D + G
Sbjct: 290 NGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAG 341
Score = 32.7 bits (73), Expect = 0.53
Identities = 34/131 (25%), Positives = 54/131 (41%), Gaps = 22/131 (16%)
Query: 19 DGLPHGFCTVTYSS--TDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQG---- 72
+G HG ++ Y+ T +EG++V K G G + G+ EG + D+ G+G
Sbjct: 185 NGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRW 244
Query: 73 VYTYEDGGVLQGTYVDGELNG-----------PAQEYDTDGRLIFKGQYKDNIRHGVCWI 121
+ T E+ G + G NG + +Y I G++ + RHG
Sbjct: 245 LTTNEE---YTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYI--GEFVNGYRHGRGKF 299
Query: 122 YYPDGGSLVGE 132
YY G GE
Sbjct: 300 YYASGAMYDGE 310
Score = 29.3 bits (64), Expect = 5.8
Identities = 22/107 (20%), Positives = 48/107 (44%), Gaps = 12/107 (11%)
Query: 18 DDGLPHGFCTVTYSST-DRFEGNFVHGEKNGRGKFFFFDGSTLE----------GYYVDD 66
+D + HG + + +T + + G + G +NG G +F G +V+
Sbjct: 232 EDNMRHGEGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNG 291
Query: 67 ALQGQGVYTYEDGGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDN 113
G+G + Y G + G +V + +G + +GR +++G + ++
Sbjct: 292 YRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGR-VYEGAFSND 337
>gi|50355990 MORN repeat containing 3 [Homo sapiens]
Length = 240
Score = 47.4 bits (111), Expect = 2e-05
Identities = 21/91 (23%), Positives = 48/91 (52%)
Query: 24 GFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYEDGGVLQ 83
G+ + + +EG++ +++G G+ ++ +G EG + +D G+G+ ++G +
Sbjct: 102 GYGIQFFGPKEYYEGDWCGSQRSGWGRMYYSNGDIYEGQWENDKPNGEGMLRLKNGNRYE 161
Query: 84 GTYVDGELNGPAQEYDTDGRLIFKGQYKDNI 114
G + G NG + + D +F+G + DN+
Sbjct: 162 GCWERGMKNGAGRFFHLDHGQLFEGFWVDNM 192
Score = 39.3 bits (90), Expect = 0.006
Identities = 21/55 (38%), Positives = 33/55 (60%), Gaps = 2/55 (3%)
Query: 13 EGHLDDDGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFD-GSTLEGYYVDD 66
EG ++D P+G + + +R+EG + G KNG G+FF D G EG++VD+
Sbjct: 138 EGQWENDK-PNGEGMLRLKNGNRYEGCWERGMKNGAGRFFHLDHGQLFEGFWVDN 191
>gi|75750529 ankyrin repeat and MYND domain containing 1 isoform 1
[Homo sapiens]
Length = 941
Score = 47.0 bits (110), Expect = 3e-05
Identities = 31/96 (32%), Positives = 41/96 (42%), Gaps = 2/96 (2%)
Query: 36 FEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYEDGGVLQGTYVDGELNGPA 95
++G F K G GKF + G + G + D G G Y + DG GT+ G
Sbjct: 2 YQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMWPDGSSFTGTFYLSHREGYG 61
Query: 96 QEYDTDGRLIFKGQYKDNIRHGVCWIYYPDGGSLVG 131
Y +F+G YK + R G YPDG VG
Sbjct: 62 TMYMK--TRLFQGLYKADQRFGPGVETYPDGSQDVG 95
Score = 32.3 bits (72), Expect = 0.69
Identities = 20/79 (25%), Positives = 34/79 (43%), Gaps = 1/79 (1%)
Query: 24 GFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYEDGGVLQ 83
G+ ++ + + + G F +G G + + DGS+ G + +G G Y + Q
Sbjct: 13 GYGKFSWPTGESYHGQFYRDHCHGLGTYMWPDGSSFTGTFYLSHREGYGT-MYMKTRLFQ 71
Query: 84 GTYVDGELNGPAQEYDTDG 102
G Y + GP E DG
Sbjct: 72 GLYKADQRFGPGVETYPDG 90
>gi|19923202 enhancer of zeste homolog 1 [Homo sapiens]
Length = 747
Score = 41.2 bits (95), Expect = 0.001
Identities = 37/119 (31%), Positives = 50/119 (42%), Gaps = 13/119 (10%)
Query: 226 AGEGLFSKVAVGPNTVMSFYNGVRITHQEVDSR----DWALNGNTLSLDEETVIDVPEPY 281
AG G F K +V N +S Y G I+ E D R D ++ +L+ + V+D
Sbjct: 623 AGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYDKYMSSFLFNLNNDFVVDATRKG 682
Query: 282 NHVSKYCASLGHKANHSFTPNCIYDMFVHPRFGPIKCIRTLRAVEADEELTVAYGYDHS 340
N + ANHS PNC Y V I RA++A EEL Y Y +
Sbjct: 683 NKI--------RFANHSVNPNC-YAKVVMVNGDHRIGIFAKRAIQAGEELFFDYRYSQA 732
>gi|224282170 MORN repeat containing 2 [Homo sapiens]
Length = 79
Score = 40.0 bits (92), Expect = 0.003
Identities = 17/57 (29%), Positives = 27/57 (47%)
Query: 46 NGRGKFFFFDGSTLEGYYVDDALQGQGVYTYEDGGVLQGTYVDGELNGPAQEYDTDG 102
NG G+ F G+ EG + D+ G G YT+ +G G + + + G + D G
Sbjct: 2 NGFGRLEHFSGAVYEGQFKDNMFHGLGTYTFPNGAKYTGNFNENRVEGEGEYTDIQG 58
Score = 33.9 bits (76), Expect = 0.24
Identities = 12/32 (37%), Positives = 21/32 (65%)
Query: 105 IFKGQYKDNIRHGVCWIYYPDGGSLVGEVNED 136
+++GQ+KDN+ HG+ +P+G G NE+
Sbjct: 14 VYEGQFKDNMFHGLGTYTFPNGAKYTGNFNEN 45
Score = 31.6 bits (70), Expect = 1.2
Identities = 17/64 (26%), Positives = 32/64 (50%)
Query: 23 HGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYEDGGVL 82
+GF + + S +EG F +G G + F +G+ G + ++ ++G+G YT G
Sbjct: 2 NGFGRLEHFSGAVYEGQFKDNMFHGLGTYTFPNGAKYTGNFNENRVEGEGEYTDIQGLEW 61
Query: 83 QGTY 86
G +
Sbjct: 62 SGNF 65
>gi|4507321 suppressor of variegation 3-9 homolog 1 [Homo sapiens]
Length = 412
Score = 38.1 bits (87), Expect = 0.013
Identities = 36/121 (29%), Positives = 53/121 (43%), Gaps = 10/121 (8%)
Query: 227 GEGLFSKVAVGPNTVMSFYNGVRITHQEVDSRD--WALNGNTLSLDEETVIDVPEPYNHV 284
G G+ + + N+ + Y G IT +E + R + G T D + V DV Y
Sbjct: 255 GWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDV---YTVD 311
Query: 285 SKYCASLGHKANHSFTPNC-IYDMFV---HPRFGPIKCIRTLRAVEADEELTVAYGYDHS 340
+ Y ++ H NHS PN +Y++F+ R I T R + A EELT Y
Sbjct: 312 AAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFAT-RTIRAGEELTFDYNMQVD 370
Query: 341 P 341
P
Sbjct: 371 P 371
>gi|23510384 enhancer of zeste 2 isoform b [Homo sapiens]
Length = 707
Score = 38.1 bits (87), Expect = 0.013
Identities = 36/122 (29%), Positives = 50/122 (40%), Gaps = 19/122 (15%)
Query: 226 AGEGLFSKVAVGPNTVMSFYNGVRITHQEVDSR----DWALNGNTLSLDEETVIDVPEPY 281
AG G+F K V N +S Y G I+ E D R D + +L+ + V+D
Sbjct: 583 AGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKG 642
Query: 282 NHVSKYCASLGHKANHSFTPNCIYDMFV---HPRFGPIKCIRTLRAVEADEELTVAYGYD 338
N + ANHS PNC + + R G I RA++ EEL Y Y
Sbjct: 643 NKI--------RFANHSVNPNCYAKVMMVNGDHRIG----IFAKRAIQTGEELFFDYRYS 690
Query: 339 HS 340
+
Sbjct: 691 QA 692
>gi|21361095 enhancer of zeste 2 isoform a [Homo sapiens]
Length = 751
Score = 38.1 bits (87), Expect = 0.013
Identities = 36/122 (29%), Positives = 50/122 (40%), Gaps = 19/122 (15%)
Query: 226 AGEGLFSKVAVGPNTVMSFYNGVRITHQEVDSR----DWALNGNTLSLDEETVIDVPEPY 281
AG G+F K V N +S Y G I+ E D R D + +L+ + V+D
Sbjct: 627 AGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKG 686
Query: 282 NHVSKYCASLGHKANHSFTPNCIYDMFV---HPRFGPIKCIRTLRAVEADEELTVAYGYD 338
N + ANHS PNC + + R G I RA++ EEL Y Y
Sbjct: 687 NKI--------RFANHSVNPNCYAKVMMVNGDHRIG----IFAKRAIQTGEELFFDYRYS 734
Query: 339 HS 340
+
Sbjct: 735 QA 736
>gi|40316935 alsin isoform 1 [Homo sapiens]
Length = 1657
Score = 38.1 bits (87), Expect = 0.013
Identities = 21/79 (26%), Positives = 40/79 (50%), Gaps = 5/79 (6%)
Query: 20 GLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLE-----GYYVDDALQGQGVY 74
G PHG + + + G F +G ++G G++ + + + G++ + + GQGVY
Sbjct: 1056 GKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKAMNKEDHYVGHWKEGKMCGQGVY 1115
Query: 75 TYEDGGVLQGTYVDGELNG 93
+Y G V +G + D +G
Sbjct: 1116 SYASGEVFEGCFQDNMRHG 1134
Score = 37.4 bits (85), Expect = 0.021
Identities = 22/87 (25%), Positives = 43/87 (49%), Gaps = 6/87 (6%)
Query: 36 FEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYEDGGVLQ-----GTYVDGE 90
++G ++ G+ +GRG + DG G + + G G Y + + + G + +G+
Sbjct: 1049 YDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKAMNKEDHYVGHWKEGK 1108
Query: 91 LNGPAQEYDTDGRLIFKGQYKDNIRHG 117
+ G G +F+G ++DN+RHG
Sbjct: 1109 MCGQGVYSYASGE-VFEGCFQDNMRHG 1134
Score = 29.3 bits (64), Expect = 5.8
Identities = 33/170 (19%), Positives = 65/170 (38%), Gaps = 8/170 (4%)
Query: 4 DDEMVEEAVEGHLDDDGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYY 63
D +M L+D + + D + G++ G+ G+G + + G EG +
Sbjct: 1068 DGKMYSGMFRNGLEDGYGEYRIPNKAMNKEDHYVGHWKEGKMCGQGVYSYASGEVFEGCF 1127
Query: 64 VDDALQGQGV-----YTYEDGGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGV 118
D+ G G+ T + G +V + G D + G ++D++ G
Sbjct: 1128 QDNMRHGHGLLRSGKLTSSSPSMFIGQWVMDKKAGYGVFDDITRGEKYMGMWQDDVCQGN 1187
Query: 119 CWIYYPDGGSLVGEVNEDGEMTGEKIAYVYPDERTALYGKFIDGEMIEGK 168
+ G G + + +M G + + ++ T G+F D + GK
Sbjct: 1188 GVVVTQFGLYYEGNFHLN-KMMGNGV--LLSEDDTIYEGEFSDDWTLSGK 1234
>gi|75750531 ankyrin repeat and MYND domain containing 1 isoform 2
[Homo sapiens]
Length = 717
Score = 37.4 bits (85), Expect = 0.021
Identities = 25/86 (29%), Positives = 34/86 (39%), Gaps = 5/86 (5%)
Query: 6 EMVEEAVEGHLDDDGLPHGFCTVTYSSTDRFEGNFVHGE-----KNGRGKFFFFDGSTLE 60
E EE EG L L + + + +G GE K G GKF + G +
Sbjct: 56 EKEEEEAEGPLRAQDLRESYIQLVQGVQEWQDGCMYQGEFGLNMKLGYGKFSWPTGESYH 115
Query: 61 GYYVDDALQGQGVYTYEDGGVLQGTY 86
G + D G G Y + DG GT+
Sbjct: 116 GQFYRDHCHGLGTYMWPDGSSFTGTF 141
>gi|21704283 junctophilin 3 [Homo sapiens]
Length = 748
Score = 36.2 bits (82), Expect = 0.048
Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 1/59 (1%)
Query: 36 FEGNFVHGEKNGRG-KFFFFDGSTLEGYYVDDALQGQGVYTYEDGGVLQGTYVDGELNG 93
++G + HG K G + +G+ EG + + G G TY DGG QG +V G G
Sbjct: 83 YKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQG 141
Score = 33.9 bits (76), Expect = 0.24
Identities = 25/86 (29%), Positives = 40/86 (46%), Gaps = 10/86 (11%)
Query: 38 GNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQG---QGVYTYEDGGVLQGTYVDGELNGP 94
G + G+ +G G G +G Y G GVYT+ G QGT+ G+ +G
Sbjct: 17 GGWEDGKAHGHG---VCTGPKGQGEYTGSWSHGFEVLGVYTWPSGNTYQGTWAQGKRHGI 73
Query: 95 AQEYDTDGRLIFKGQYKDNI--RHGV 118
E + G+ ++KG++ R+GV
Sbjct: 74 GLE--SKGKWVYKGEWTHGFKGRYGV 97
Score = 31.6 bits (70), Expect = 1.2
Identities = 14/39 (35%), Positives = 23/39 (58%)
Query: 35 RFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGV 73
++EG + +G ++G G + DG T +G +V QG GV
Sbjct: 106 KYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGV 144
Score = 31.2 bits (69), Expect = 1.5
Identities = 17/63 (26%), Positives = 30/63 (47%)
Query: 31 SSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYEDGGVLQGTYVDGE 90
++T+ + G + + +++G G DG EG + + G G T+ DG +G Y
Sbjct: 283 TTTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNI 342
Query: 91 LNG 93
L G
Sbjct: 343 LVG 345
>gi|21704281 junctophilin 2 isoform 1 [Homo sapiens]
Length = 696
Score = 35.4 bits (80), Expect = 0.081
Identities = 19/59 (32%), Positives = 29/59 (49%), Gaps = 1/59 (1%)
Query: 36 FEGNFVHGEKNGRG-KFFFFDGSTLEGYYVDDALQGQGVYTYEDGGVLQGTYVDGELNG 93
++G + HG K G + G+ EG + + G G TY DGG QG + +G +G
Sbjct: 82 YKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHG 140
Score = 31.2 bits (69), Expect = 1.5
Identities = 28/118 (23%), Positives = 47/118 (39%), Gaps = 26/118 (22%)
Query: 23 HGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYT------- 75
HG CT + + G++ G + G + + G+T EGY+ G G+ T
Sbjct: 26 HGLCTGPKGQGE-YSGSWNFGFEVA-GVYTWPSGNTFEGYWSQGKRHGLGIETKGRWLYK 83
Query: 76 ----------------YEDGGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHG 117
G +GT+ +G +G E DG ++GQ+ + +RHG
Sbjct: 84 GEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGTETYADGG-TYQGQFTNGMRHG 140
Score = 30.4 bits (67), Expect = 2.6
Identities = 14/43 (32%), Positives = 24/43 (55%)
Query: 31 SSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGV 73
SS ++EG + +G ++G G + DG T +G + + G GV
Sbjct: 101 SSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGV 143
Score = 29.6 bits (65), Expect = 4.5
Identities = 21/77 (27%), Positives = 36/77 (46%), Gaps = 3/77 (3%)
Query: 10 EAVEGHLDDDGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQ 69
EA EG D+ P + ++T+ + G + + +++G G G EG ++D+
Sbjct: 268 EAAEGA--DEAAPFE-ADIDATTTETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRH 324
Query: 70 GQGVYTYEDGGVLQGTY 86
G G T DG +G Y
Sbjct: 325 GYGCTTLPDGHREEGKY 341
Score = 28.9 bits (63), Expect = 7.6
Identities = 11/32 (34%), Positives = 20/32 (62%)
Query: 18 DDGLPHGFCTVTYSSTDRFEGNFVHGEKNGRG 49
++GL G+ T TY+ ++G F +G ++G G
Sbjct: 111 NNGLQDGYGTETYADGGTYQGQFTNGMRHGYG 142
>gi|223278407 MORN repeat containing 5 [Homo sapiens]
Length = 161
Score = 35.4 bits (80), Expect = 0.081
Identities = 17/43 (39%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 84 GTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCWIYYPDG 126
G YVDG + G A+ Y I+ G+ KD + HG +Y+P G
Sbjct: 10 GEYVDGRMEGKAK-YILPTETIYVGEMKDGMFHGEGTLYFPSG 51
>gi|225690502 junctophilin 4 [Homo sapiens]
Length = 628
Score = 34.7 bits (78), Expect = 0.14
Identities = 18/58 (31%), Positives = 26/58 (44%)
Query: 36 FEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYEDGGVLQGTYVDGELNG 93
+ G ++ G K G + G G + D G G TY DGG QG + G+ +G
Sbjct: 83 YRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYSDGGTYQGQWQAGKRHG 140
Score = 32.7 bits (73), Expect = 0.53
Identities = 33/137 (24%), Positives = 60/137 (43%), Gaps = 5/137 (3%)
Query: 20 GLPHGFCTVTYSSTD-RFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYED 78
G HG+ T + G + HG ++ G F G + +G++ +G GV +
Sbjct: 22 GRAHGYGVCTGPGAQGEYSGCWAHGFES-LGVFTGPGGHSYQGHWQQGKREGLGVER-KS 79
Query: 79 GGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCWIYYPDGGSLVGEVNEDGE 138
+G ++ G L G + +++ L + G +KD + G Y DGG+ G+ + G+
Sbjct: 80 RWTYRGEWLGG-LKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYSDGGTYQGQW-QAGK 137
Query: 139 MTGEKIAYVYPDERTAL 155
G + P + AL
Sbjct: 138 RHGYGVRQSVPYHQAAL 154
>gi|225690500 junctophilin 4 [Homo sapiens]
Length = 628
Score = 34.7 bits (78), Expect = 0.14
Identities = 18/58 (31%), Positives = 26/58 (44%)
Query: 36 FEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYEDGGVLQGTYVDGELNG 93
+ G ++ G K G + G G + D G G TY DGG QG + G+ +G
Sbjct: 83 YRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYSDGGTYQGQWQAGKRHG 140
Score = 32.7 bits (73), Expect = 0.53
Identities = 33/137 (24%), Positives = 60/137 (43%), Gaps = 5/137 (3%)
Query: 20 GLPHGFCTVTYSSTD-RFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYED 78
G HG+ T + G + HG ++ G F G + +G++ +G GV +
Sbjct: 22 GRAHGYGVCTGPGAQGEYSGCWAHGFES-LGVFTGPGGHSYQGHWQQGKREGLGVER-KS 79
Query: 79 GGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCWIYYPDGGSLVGEVNEDGE 138
+G ++ G L G + +++ L + G +KD + G Y DGG+ G+ + G+
Sbjct: 80 RWTYRGEWLGG-LKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYSDGGTYQGQW-QAGK 137
Query: 139 MTGEKIAYVYPDERTAL 155
G + P + AL
Sbjct: 138 RHGYGVRQSVPYHQAAL 154
>gi|21735575 junctophilin 1 [Homo sapiens]
Length = 661
Score = 34.3 bits (77), Expect = 0.18
Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 26/97 (26%)
Query: 23 HGFCTV---TYSSTDRFEGNFVHGEKNG-----RGKFFF-------FDG----------- 56
HGF V T+ S + ++G + G+++G +GK+ + F G
Sbjct: 44 HGFEVVGGYTWPSGNTYQGYWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTP 103
Query: 57 STLEGYYVDDALQGQGVYTYEDGGVLQGTYVDGELNG 93
+ EG + + G GV TY DGG QG + G +G
Sbjct: 104 ARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHG 140
Score = 30.0 bits (66), Expect = 3.4
Identities = 23/95 (24%), Positives = 38/95 (40%), Gaps = 27/95 (28%)
Query: 49 GKFFFFDGSTLEGYYVDDALQGQGV-----------------------YTYEDGGVLQGT 85
G+F F DG T G + + G G+ YT+ G QG
Sbjct: 4 GRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQGY 63
Query: 86 YVDGELNGPAQEYDTDGRLIFKGQYKDNI--RHGV 118
+ G+ +G E T G+ +++G++ R+GV
Sbjct: 64 WAQGKRHGLGVE--TKGKWMYRGEWSHGFKGRYGV 96
Score = 30.0 bits (66), Expect = 3.4
Identities = 15/59 (25%), Positives = 29/59 (49%)
Query: 28 VTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYEDGGVLQGTY 86
V ++T+ + G + + ++NG G +G EG + ++ G G + DG +G Y
Sbjct: 273 VDATTTETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKY 331
Score = 29.6 bits (65), Expect = 4.5
Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 1/67 (1%)
Query: 2 DSDDEMVEEAVEGHLDDDGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEG 61
D D E G +D +GF S+ ++EG + + +++G G F DGS EG
Sbjct: 271 DHVDATTTETYMGEWKNDKR-NGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEG 329
Query: 62 YYVDDAL 68
Y ++ L
Sbjct: 330 KYKNNIL 336
Score = 28.9 bits (63), Expect = 7.6
Identities = 16/54 (29%), Positives = 25/54 (46%), Gaps = 5/54 (9%)
Query: 20 GLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGV 73
G+ CT R+EG + +G ++G G + DG T +G + G GV
Sbjct: 95 GVRQSLCTPA-----RYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGV 143
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 33.1 bits (74), Expect = 0.40
Identities = 29/116 (25%), Positives = 49/116 (42%), Gaps = 14/116 (12%)
Query: 227 GEGLFSKVAVGPNTVMSFYNGVRITHQEVDSRDWALNGNTLS-----LDEETVIDVPEPY 281
G GLF K + ++ Y+G+ I D R+ +G + +D+ V+D +
Sbjct: 2586 GRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKREKFYDGKGIGCYMFRMDDFDVVDA-TMH 2644
Query: 282 NHVSKYCASLGHKANHSFTPNCIYDMFVHPRFGPIKCIRTLRAVEADEELTVAYGY 337
+ +++ NHS PNC + +H I LR + EELT Y +
Sbjct: 2645 GNAARF-------INHSCEPNC-FSRVIHVEGQKHIVIFALRRILRGEELTYDYKF 2692
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 32.7 bits (73), Expect = 0.53
Identities = 31/130 (23%), Positives = 51/130 (39%), Gaps = 18/130 (13%)
Query: 229 GLFSKVAVGPNTVMSFYNGVRITHQEVDSRDWAL------NGNTLSLDEETVIDVPEPYN 282
GLF+ + + ++ Y G I D R+ + +D +T+ID +
Sbjct: 1581 GLFAMEPIAADEMVIEYVGQNIRQMVADMREKRYVQEGIGSSYLFRVDHDTIIDATK--- 1637
Query: 283 HVSKYCASLGHKANHSFTPNCIYDMFVHPRFGPIKCIRTLRAVEADEELTVAYGY---DH 339
C +L NH TPNC Y + I + + + DEE+T Y + D+
Sbjct: 1638 -----CGNLARFINHCCTPNC-YAKVITIESQKKIVIYSKQPIGVDEEITYDYKFPLEDN 1691
Query: 340 SPPGKSGPEA 349
P G E+
Sbjct: 1692 KIPCLCGTES 1701
>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
sapiens]
Length = 4911
Score = 32.7 bits (73), Expect = 0.53
Identities = 31/128 (24%), Positives = 53/128 (41%), Gaps = 16/128 (12%)
Query: 216 VYVAESLISSAGEGLFSKVAVGPNTVMSFYNGVRITHQEVDSRDWALNGNT-----LSLD 270
VY+A S I G GL++ + +T++ Y G I ++ + ++ +D
Sbjct: 4773 VYLARSRIQ--GLGLYAARDIEKHTMVIEYIGTIIRNEVANRKEKLYESQNRGVYMFRMD 4830
Query: 271 EETVIDVPEPYNHVSKYCASLGHKANHSFTPNCIYDMFVHPRFGPIKCIRTLRAVEADEE 330
+ VID + NHS PNC+ ++ R G I + R ++ EE
Sbjct: 4831 NDHVID--------ATLTGGPARYINHSCAPNCVAEVVTFER-GHKIIISSSRRIQKGEE 4881
Query: 331 LTVAYGYD 338
L Y +D
Sbjct: 4882 LCYDYKFD 4889
>gi|238624099 SET domain, bifurcated 2 isoform b [Homo sapiens]
Length = 707
Score = 32.0 bits (71), Expect = 0.90
Identities = 21/52 (40%), Positives = 29/52 (55%), Gaps = 3/52 (5%)
Query: 290 SLGHKANHSFTPNC-IYDMFV--HPRFGPIKCIRTLRAVEADEELTVAYGYD 338
++G NHS PN + ++FV H R P+ T R V+A ELT YGY+
Sbjct: 633 NVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTELTWDYGYE 684
>gi|238624095 SET domain, bifurcated 2 isoform a [Homo sapiens]
Length = 719
Score = 32.0 bits (71), Expect = 0.90
Identities = 21/52 (40%), Positives = 29/52 (55%), Gaps = 3/52 (5%)
Query: 290 SLGHKANHSFTPNC-IYDMFV--HPRFGPIKCIRTLRAVEADEELTVAYGYD 338
++G NHS PN + ++FV H R P+ T R V+A ELT YGY+
Sbjct: 645 NVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTELTWDYGYE 696
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 32.0 bits (71), Expect = 0.90
Identities = 32/128 (25%), Positives = 53/128 (41%), Gaps = 16/128 (12%)
Query: 216 VYVAESLISSAGEGLFSKVAVGPNTVMSFYNGVRITHQEVDSRDWALNGNT-----LSLD 270
VY+A S I G GL++ + +T++ Y G I ++ + R+ ++
Sbjct: 5399 VYLARSRIQ--GLGLYAAKDLEKHTMVIEYIGTIIRNEVANRREKIYEEQNRGIYMFRIN 5456
Query: 271 EETVIDVPEPYNHVSKYCASLGHKANHSFTPNCIYDMFVHPRFGPIKCIRTLRAVEADEE 330
E VID + NHS PNC+ ++ + I I + R + EE
Sbjct: 5457 NEHVID--------ATLTGGPARYINHSCAPNCVAEVVTFDKEDKIIIISS-RRIPKGEE 5507
Query: 331 LTVAYGYD 338
LT Y +D
Sbjct: 5508 LTYDYQFD 5515
>gi|31543169 suppressor of variegation 4-20 homolog 2 [Homo sapiens]
Length = 462
Score = 32.0 bits (71), Expect = 0.90
Identities = 17/41 (41%), Positives = 22/41 (53%), Gaps = 4/41 (9%)
Query: 296 NHSFTPNCIYDMFVHPRFGPIKCIRTLRAVEADEELTVAYG 336
NH PNC FV P G C++ LR +E +E+T YG
Sbjct: 182 NHDCKPNC---KFV-PADGNAACVKVLRDIEPGDEVTCFYG 218
>gi|33359215 ALS2 C-terminal like isoform 1 [Homo sapiens]
Length = 953
Score = 31.2 bits (69), Expect = 1.5
Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 8/129 (6%)
Query: 9 EEAVEGHLDDDGLPHGFCTVTYSSTD----RFEGNFVHGEKNGRGKFFFFD-GSTLEGYY 63
+E +G+ + GL HGF + R+ G++ G+++G G D G G +
Sbjct: 429 DEVYKGYFQE-GLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEEDGDRGERYIGMW 487
Query: 64 VDDALQGQGVYTYEDGGVLQGTYVDGELNGPAQEYDTDGRLIFKGQY-KDNIRHGVCWIY 122
G GV + G QGT+ + GP D L ++G + +D G +
Sbjct: 488 QAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSL-YEGTFTRDLTLMGKGKVT 546
Query: 123 YPDGGSLVG 131
+P+G +L G
Sbjct: 547 FPNGFTLEG 555
Score = 30.8 bits (68), Expect = 2.0
Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 1/75 (1%)
Query: 20 GLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDD-ALQGQGVYTYED 78
G HG + + ++G F + G G D S EG + D L G+G T+ +
Sbjct: 490 GQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTRDLTLMGKGKVTFPN 549
Query: 79 GGVLQGTYVDGELNG 93
G L+G++ G G
Sbjct: 550 GFTLEGSFGSGAGRG 564
Score = 29.3 bits (64), Expect = 5.8
Identities = 21/88 (23%), Positives = 38/88 (43%), Gaps = 8/88 (9%)
Query: 36 FEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYEDGG-----VLQGTYVDGE 90
+EG + G +G+G + DG G + G G+ + + +G
Sbjct: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGS 417
Query: 91 LNG-PAQEYDTDGRLIFKGQYKDNIRHG 117
+ G EY TD ++KG +++ +RHG
Sbjct: 418 MCGYGICEYSTDE--VYKGYFQEGLRHG 443
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.137 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,778,908
Number of Sequences: 37866
Number of extensions: 766975
Number of successful extensions: 1274
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 1134
Number of HSP's gapped (non-prelim): 115
length of query: 366
length of database: 18,247,518
effective HSP length: 104
effective length of query: 262
effective length of database: 14,309,454
effective search space: 3749076948
effective search space used: 3749076948
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.