Guide to the Human Genome
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Search of human proteins with 18104940

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|18104940 cystatin 9-like precursor [Homo sapiens]
         (147 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|18104940 cystatin 9-like precursor [Homo sapiens]                  315   7e-87
gi|226529477 cystatin 9 precursor [Homo sapiens]                      110   3e-25
gi|4503105 cystatin SA precursor [Homo sapiens]                        65   2e-11
gi|19882259 cystatin-like 1 precursor [Homo sapiens]                   64   3e-11
gi|19882249 cystatin 11 isoform 1 precursor [Homo sapiens]             59   1e-09
gi|4503107 cystatin C precursor [Homo sapiens]                         58   3e-09
gi|4503109 cystatin S precursor [Homo sapiens]                         57   4e-09
gi|19882251 cystatin SN precursor [Homo sapiens]                       55   2e-08
gi|19882256 cystatin D precursor [Homo sapiens]                        52   2e-07
gi|4885163 cystatin 8 precursor [Homo sapiens]                         49   2e-06
gi|239751973 PREDICTED: hypothetical protein XP_002348052 [Homo ...    44   4e-05
gi|239746455 PREDICTED: hypothetical protein XP_002344215 [Homo ...    44   4e-05
gi|169214772 PREDICTED: similar to hCG1783157 [Homo sapiens]           44   5e-05
gi|20302139 cystatin F [Homo sapiens]                                  44   5e-05
gi|18644732 cystatin 11 isoform 2 precursor [Homo sapiens]             41   3e-04
gi|4503113 cystatin M precursor [Homo sapiens]                         33   0.086
gi|150036266 cytochrome P450, family 4, subfamily F, polypeptide...    29   1.6  
gi|22507409 TBC1 domain family, member 22A [Homo sapiens]              28   2.8  
gi|30410728 fucosyltransferase 8 isoform a [Homo sapiens]              27   6.1  
gi|30410726 fucosyltransferase 8 isoform a [Homo sapiens]              27   6.1  
gi|30410724 fucosyltransferase 8 isoform a [Homo sapiens]              27   6.1  

>gi|18104940 cystatin 9-like precursor [Homo sapiens]
          Length = 147

 Score =  315 bits (808), Expect = 7e-87
 Identities = 147/147 (100%), Positives = 147/147 (100%)

Query: 1   MLGLPWKGGLSWALLLLLLGSQILLIYAWHFHEQRDCDEHNVMARYLPATVEFAVHTFNQ 60
           MLGLPWKGGLSWALLLLLLGSQILLIYAWHFHEQRDCDEHNVMARYLPATVEFAVHTFNQ
Sbjct: 1   MLGLPWKGGLSWALLLLLLGSQILLIYAWHFHEQRDCDEHNVMARYLPATVEFAVHTFNQ 60

Query: 61  QSKDYYAYRLGHILNSWKEQVESKTVFSMELLLGRTRCGKFEDDIDNCHFQESTELNNTF 120
           QSKDYYAYRLGHILNSWKEQVESKTVFSMELLLGRTRCGKFEDDIDNCHFQESTELNNTF
Sbjct: 61  QSKDYYAYRLGHILNSWKEQVESKTVFSMELLLGRTRCGKFEDDIDNCHFQESTELNNTF 120

Query: 121 TCFFTISTRPWMTQFSLLNKTCLEGFH 147
           TCFFTISTRPWMTQFSLLNKTCLEGFH
Sbjct: 121 TCFFTISTRPWMTQFSLLNKTCLEGFH 147


>gi|226529477 cystatin 9 precursor [Homo sapiens]
          Length = 159

 Score =  110 bits (276), Expect = 3e-25
 Identities = 60/114 (52%), Positives = 75/114 (65%), Gaps = 5/114 (4%)

Query: 10  LSWALLLLLLGSQILLIYAWHFHEQRDCDEHNVMARYLPATVEFAVHTFNQQSKDYYAYR 69
           + WAL LLL+G Q+L+ YAW   E+   +   V      ATVEFA++TFN QSK+ +AYR
Sbjct: 10  MPWALSLLLMGFQLLVTYAWCSEEEMGGNNKIVQDPMFLATVEFALNTFNVQSKEEHAYR 69

Query: 70  LGHILNSWKE-----QVESKTVFSMELLLGRTRCGKFEDDIDNCHFQESTELNN 118
           L  +L+SW+E     +   K VFSM L L +T C KFEDDIDNC FQES ELNN
Sbjct: 70  LLRVLSSWREDSMDRKWRGKMVFSMNLQLRQTVCRKFEDDIDNCPFQESLELNN 123


>gi|4503105 cystatin SA precursor [Homo sapiens]
          Length = 141

 Score = 65.1 bits (157), Expect = 2e-11
 Identities = 43/142 (30%), Positives = 69/142 (48%), Gaps = 9/142 (6%)

Query: 10  LSWAL--LLLLLGSQILLIYAWHFHEQRDCDEHNVMARYL-----PATVEFAVHTFNQQS 62
           ++W L  LLLLL +Q + + AW   E+    E  +    L        + F +  +N+ +
Sbjct: 1   MAWPLCTLLLLLATQAVAL-AWSPQEEDRIIEGGIYDADLNDERVQRALHFVISEYNKAT 59

Query: 63  KDYYAYRLGHILNSWKEQVESKTVFSMELLLGRTRCGKFEDDIDNCHFQESTELNNTFTC 122
           +D Y  RL  +L + +EQ+     +  ++ +GRT C K + ++D C F E  EL     C
Sbjct: 60  EDEYYRRLLRVLRA-REQIVGGVNYFFDIEVGRTICTKSQPNLDTCAFHEQPELQKKQLC 118

Query: 123 FFTISTRPWMTQFSLLNKTCLE 144
            F I   PW  + SL+N  C E
Sbjct: 119 SFQIYEVPWEDRMSLVNSRCQE 140


>gi|19882259 cystatin-like 1 precursor [Homo sapiens]
          Length = 145

 Score = 64.3 bits (155), Expect = 3e-11
 Identities = 37/136 (27%), Positives = 66/136 (48%), Gaps = 2/136 (1%)

Query: 12  WALLLLLLGSQILLIYAWHFHEQRDCDEHNVMARYLPATVEFAVHTFNQQSKDYYAYRLG 71
           W   LLLL + +L     HF       +  +  + + +T+ F + ++N  S D Y YR+ 
Sbjct: 6   WRNPLLLLIALVLSAKLGHFQRWEGFQQKLMSKKNMNSTLNFFIQSYNNASNDTYLYRVQ 65

Query: 72  HILNSWKEQVESKTVFSMELLLGRTRCGKFEDDIDNCHFQESTELNNTFTCFFTISTRPW 131
            ++ S + Q+ +   + + + +G T+C + +    +C  Q S +L  +  C   I T PW
Sbjct: 66  RLIRS-QMQLTTGVEYIVTVKIGWTKCKRNDTSNSSCPLQ-SKKLRKSLICESLIYTMPW 123

Query: 132 MTQFSLLNKTCLEGFH 147
           +  F L N +CLE  H
Sbjct: 124 INYFQLWNNSCLEAEH 139


>gi|19882249 cystatin 11 isoform 1 precursor [Homo sapiens]
          Length = 138

 Score = 58.9 bits (141), Expect = 1e-09
 Identities = 42/144 (29%), Positives = 69/144 (47%), Gaps = 11/144 (7%)

Query: 1   MLGLPWKGGLSWALLLLLLGSQILLIYAWHFHEQRDCDEHNVMA--RYLPATVEFAVHTF 58
           M+  PW+     AL LLL     L+   +   ++     H VMA   Y   ++++    +
Sbjct: 1   MMAEPWQ-----ALQLLLAILLTLMALPYQARKKTFLSVHEVMAVENYAKDSLQWITDQY 55

Query: 59  NQQSKDYYAYRLGHILNSWKEQVESKTVFSMELLLGRTRCGKFEDDIDNCHFQESTELNN 118
           N++S D Y +R+  +L   + QV     + + + +  T C K E    NC  QE  EL+ 
Sbjct: 56  NKESDDKYHFRIFRVLKV-QRQVTDHLEYHLNVEMQWTTCQKPETT--NCVPQER-ELHK 111

Query: 119 TFTCFFTISTRPWMTQFSLLNKTC 142
              CFF++   PW  Q+ +LNK+C
Sbjct: 112 QVNCFFSVFAVPWFEQYKILNKSC 135


>gi|4503107 cystatin C precursor [Homo sapiens]
          Length = 146

 Score = 57.8 bits (138), Expect = 3e-09
 Identities = 30/92 (32%), Positives = 46/92 (50%), Gaps = 1/92 (1%)

Query: 51  VEFAVHTFNQQSKDYYAYRLGHILNSWKEQVESKTVFSMELLLGRTRCGKFEDDIDNCHF 110
           ++FAV  +N+ S D Y  R   ++ + K+ V     F +++ LGRT C K + ++DNC F
Sbjct: 53  LDFAVGEYNKASNDMYHSRALQVVRARKQIVAGVNYF-LDVELGRTTCTKTQPNLDNCPF 111

Query: 111 QESTELNNTFTCFFTISTRPWMTQFSLLNKTC 142
            +   L     C F I   PW    +L   TC
Sbjct: 112 HDQPHLKRKAFCSFQIYAVPWQGTMTLSKSTC 143


>gi|4503109 cystatin S precursor [Homo sapiens]
          Length = 141

 Score = 57.4 bits (137), Expect = 4e-09
 Identities = 30/99 (30%), Positives = 50/99 (50%), Gaps = 1/99 (1%)

Query: 46  YLPATVEFAVHTFNQQSKDYYAYRLGHILNSWKEQVESKTVFSMELLLGRTRCGKFEDDI 105
           ++   + FA+  +N+ ++D Y  R   +L + +EQ      +  ++ +GRT C K + ++
Sbjct: 43  WVQRALHFAISEYNKATEDEYYRRPLQVLRA-REQTFGGVNYFFDVEVGRTICTKSQPNL 101

Query: 106 DNCHFQESTELNNTFTCFFTISTRPWMTQFSLLNKTCLE 144
           D C F E  EL     C F I   PW  + SL+N  C E
Sbjct: 102 DTCAFHEQPELQKKQLCSFEIYEVPWEDRMSLVNSRCQE 140


>gi|19882251 cystatin SN precursor [Homo sapiens]
          Length = 141

 Score = 55.5 bits (132), Expect = 2e-08
 Identities = 37/134 (27%), Positives = 61/134 (45%), Gaps = 6/134 (4%)

Query: 16  LLLLGSQILLIYAWHFHEQRDCDEHNVMA-----RYLPATVEFAVHTFNQQSKDYYAYRL 70
           LLLL + + +  AW   E+       +        ++   + FA+  +N+ +KD Y  R 
Sbjct: 8   LLLLLATLAVALAWSPKEEDRIIPGGIYNADLNDEWVQRALHFAISEYNKATKDDYYRRP 67

Query: 71  GHILNSWKEQVESKTVFSMELLLGRTRCGKFEDDIDNCHFQESTELNNTFTCFFTISTRP 130
             +L + ++ V     F  ++ +GRT C K + ++D C F E  EL     C F I   P
Sbjct: 68  LRVLRARQQTVGGVNYF-FDVEVGRTICTKSQPNLDTCAFHEQPELQKKQLCSFEIYEVP 126

Query: 131 WMTQFSLLNKTCLE 144
           W  + SL+   C E
Sbjct: 127 WENRRSLVKSRCQE 140


>gi|19882256 cystatin D precursor [Homo sapiens]
          Length = 142

 Score = 52.0 bits (123), Expect = 2e-07
 Identities = 27/93 (29%), Positives = 49/93 (52%), Gaps = 2/93 (2%)

Query: 51  VEFAVHTFNQQ-SKDYYAYRLGHILNSWKEQVESKTVFSMELLLGRTRCGKFEDDIDNCH 109
           ++FA+  +N+  +KD Y  R   ++ ++ +Q+     +   +  GRT C K + ++DNC 
Sbjct: 48  LDFAISEYNKVINKDEYYSRPLQVMAAY-QQIVGGVNYYFNVKFGRTTCTKSQPNLDNCP 106

Query: 110 FQESTELNNTFTCFFTISTRPWMTQFSLLNKTC 142
           F +  +L     C F I+  PW  + S+LN  C
Sbjct: 107 FNDQPKLKEEEFCSFQINEVPWEDKISILNYKC 139


>gi|4885163 cystatin 8 precursor [Homo sapiens]
          Length = 142

 Score = 48.5 bits (114), Expect = 2e-06
 Identities = 23/90 (25%), Positives = 49/90 (54%), Gaps = 1/90 (1%)

Query: 53  FAVHTFNQQSKDYYAYRLGHILNSWKEQVESKTVFSMELLLGRTRCGKFEDDIDNCHFQE 112
           FA+  +N++S+D Y + +   L + + QV +   + +++ + R+ C K     + C  QE
Sbjct: 51  FAMQEYNKESEDKYVFLVVKTLQA-QLQVTNLLEYLIDVEIARSDCRKPLSTNEICAIQE 109

Query: 113 STELNNTFTCFFTISTRPWMTQFSLLNKTC 142
           +++L    +C F +   PW  +F+++ K C
Sbjct: 110 NSKLKRKLSCSFLVGALPWNGEFTVMEKKC 139


>gi|239751973 PREDICTED: hypothetical protein XP_002348052 [Homo
           sapiens]
          Length = 537

 Score = 44.3 bits (103), Expect = 4e-05
 Identities = 29/87 (33%), Positives = 42/87 (48%), Gaps = 17/87 (19%)

Query: 45  RYLPATVEFAVHTFNQQSKDYYAYRL---------------GHILNSWKEQVESKTVFSM 89
           +Y  A++EFAV  FN+ + + Y +RL                H  NS      SK V   
Sbjct: 390 QYFVASMEFAVAQFNEDNMEEYTHRLLEVQRAQQKVSGSHFVHSQNSLHRLNSSKPVVMA 449

Query: 90  --ELLLGRTRCGKFEDDIDNCHFQEST 114
             +L +G T C K+++DIDNC  QE +
Sbjct: 450 AGDLEMGLTICKKYDEDIDNCPLQEGS 476


>gi|239746455 PREDICTED: hypothetical protein XP_002344215 [Homo
           sapiens]
          Length = 537

 Score = 44.3 bits (103), Expect = 4e-05
 Identities = 29/87 (33%), Positives = 42/87 (48%), Gaps = 17/87 (19%)

Query: 45  RYLPATVEFAVHTFNQQSKDYYAYRL---------------GHILNSWKEQVESKTVFSM 89
           +Y  A++EFAV  FN+ + + Y +RL                H  NS      SK V   
Sbjct: 390 QYFVASMEFAVAQFNEDNMEEYTHRLLEVQRAQQKVSGSHFVHSQNSLHRLNSSKPVVMA 449

Query: 90  --ELLLGRTRCGKFEDDIDNCHFQEST 114
             +L +G T C K+++DIDNC  QE +
Sbjct: 450 AGDLEMGLTICKKYDEDIDNCPLQEGS 476


>gi|169214772 PREDICTED: similar to hCG1783157 [Homo sapiens]
          Length = 538

 Score = 43.9 bits (102), Expect = 5e-05
 Identities = 26/87 (29%), Positives = 43/87 (49%), Gaps = 17/87 (19%)

Query: 45  RYLPATVEFAVHTFNQQSKDYYAYRLGHILNSWKEQVESKTVFSM--------------- 89
           +Y  A++EFAV  FN+ + + Y +RL  +  + ++   S  V S                
Sbjct: 391 QYFVASMEFAVAQFNEDNMEEYTHRLLEVQRAQQKVSGSHFVHSQNSLHRLNSSKPGVMA 450

Query: 90  --ELLLGRTRCGKFEDDIDNCHFQEST 114
             +L +G T C K+++DIDNC  QE +
Sbjct: 451 AGDLEMGLTICKKYDEDIDNCPLQEGS 477


>gi|20302139 cystatin F [Homo sapiens]
          Length = 167

 Score = 43.9 bits (102), Expect = 5e-05
 Identities = 22/86 (25%), Positives = 44/86 (51%), Gaps = 2/86 (2%)

Query: 53  FAVHTFNQQSKDYYAYRLGHILNSWKEQVESKTVFSMELLLGRTRCGKFED-DIDNCHFQ 111
           ++V  FN  + D + ++   I  +  + V+    + +E+ +GRT C K +   +D+C FQ
Sbjct: 77  YSVEKFNNCTNDMFLFKESRITRALVQIVKGLK-YMLEVEIGRTTCKKNQHLRLDDCDFQ 135

Query: 112 ESTELNNTFTCFFTISTRPWMTQFSL 137
            +  L  T +C+  +   PW+  F +
Sbjct: 136 TNHTLKQTLSCYSEVWVVPWLQHFEV 161


>gi|18644732 cystatin 11 isoform 2 precursor [Homo sapiens]
          Length = 103

 Score = 41.2 bits (95), Expect = 3e-04
 Identities = 32/144 (22%), Positives = 55/144 (38%), Gaps = 46/144 (31%)

Query: 1   MLGLPWKGGLSWALLLLLLGSQILLIYAWHFHEQRDCDEHNVMA--RYLPATVEFAVHTF 58
           M+  PW+     AL LLL     L+   +   ++     H VMA   Y   ++++    +
Sbjct: 1   MMAEPWQ-----ALQLLLAILLTLMALPYQARKKTFLSVHEVMAVENYAKDSLQWITDQY 55

Query: 59  NQQSKDYYAYRLGHILNSWKEQVESKTVFSMELLLGRTRCGKFEDDIDNCHFQESTELNN 118
           N++S D Y +R+  +L   ++QV                                     
Sbjct: 56  NKESDDKYHFRIFRVLKVQRQQV------------------------------------- 78

Query: 119 TFTCFFTISTRPWMTQFSLLNKTC 142
              CFF++   PW  Q+ +LNK+C
Sbjct: 79  --NCFFSVFAVPWFEQYKILNKSC 100


>gi|4503113 cystatin M precursor [Homo sapiens]
          Length = 149

 Score = 33.1 bits (74), Expect = 0.086
 Identities = 23/96 (23%), Positives = 37/96 (38%), Gaps = 7/96 (7%)

Query: 54  AVHTFNQQSKDYYAYRLGHILNSWKEQVESKTVFSMELLLGRTRCGKFED-----DIDNC 108
           AV ++N  S   Y +R  HI+ +  + V     F + + +G T C K        D+  C
Sbjct: 55  AVASYNMGSNSIYYFRDTHIIKAQSQLVAGIKYF-LTMEMGSTDCRKTRVTGDHVDLTTC 113

Query: 109 HFQESTELNNTFTCFFTISTRPWMTQFSLLNKTCLE 144
                 +      C F +   PW     LL   C++
Sbjct: 114 PLAAGAQ-QEKLRCDFEVLVVPWQNSSQLLKHNCVQ 148


>gi|150036266 cytochrome P450, family 4, subfamily F, polypeptide
          12 [Homo sapiens]
          Length = 524

 Score = 28.9 bits (63), Expect = 1.6
 Identities = 18/43 (41%), Positives = 25/43 (58%), Gaps = 6/43 (13%)

Query: 1  MLGLPWKG----GLS-WALLLLLLGSQILL-IYAWHFHEQRDC 37
          +L LPW G     +S W LLLL++GS +L  I AW +    +C
Sbjct: 3  LLSLPWLGLRPVAMSPWLLLLLVVGSWLLARILAWTYAFYNNC 45


>gi|22507409 TBC1 domain family, member 22A [Homo sapiens]
          Length = 517

 Score = 28.1 bits (61), Expect = 2.8
 Identities = 13/44 (29%), Positives = 26/44 (59%), Gaps = 1/44 (2%)

Query: 42  VMARYLPATVEFAVHTFNQQSKDYYAYRLGHILNSWKEQVESKT 85
           +++ YLPA V+    T  ++ K+Y+A+ + H  +S  ++V   T
Sbjct: 234 LLSGYLPANVDRRPATLQRKQKEYFAF-IEHYYDSRNDEVHQDT 276


>gi|30410728 fucosyltransferase 8 isoform a [Homo sapiens]
          Length = 575

 Score = 26.9 bits (58), Expect = 6.1
 Identities = 10/37 (27%), Positives = 15/37 (40%)

Query: 5  PWKGGLSWALLLLLLGSQILLIYAWHFHEQRDCDEHN 41
          PW G   W +L+L     +L     H     D  +H+
Sbjct: 3  PWTGSWRWIMLILFAWGTLLFYIGGHLVRDNDHPDHS 39


>gi|30410726 fucosyltransferase 8 isoform a [Homo sapiens]
          Length = 575

 Score = 26.9 bits (58), Expect = 6.1
 Identities = 10/37 (27%), Positives = 15/37 (40%)

Query: 5  PWKGGLSWALLLLLLGSQILLIYAWHFHEQRDCDEHN 41
          PW G   W +L+L     +L     H     D  +H+
Sbjct: 3  PWTGSWRWIMLILFAWGTLLFYIGGHLVRDNDHPDHS 39


>gi|30410724 fucosyltransferase 8 isoform a [Homo sapiens]
          Length = 575

 Score = 26.9 bits (58), Expect = 6.1
 Identities = 10/37 (27%), Positives = 15/37 (40%)

Query: 5  PWKGGLSWALLLLLLGSQILLIYAWHFHEQRDCDEHN 41
          PW G   W +L+L     +L     H     D  +H+
Sbjct: 3  PWTGSWRWIMLILFAWGTLLFYIGGHLVRDNDHPDHS 39


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.138    0.457 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,619,302
Number of Sequences: 37866
Number of extensions: 219773
Number of successful extensions: 598
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 571
Number of HSP's gapped (non-prelim): 22
length of query: 147
length of database: 18,247,518
effective HSP length: 93
effective length of query: 54
effective length of database: 14,725,980
effective search space: 795202920
effective search space used: 795202920
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 57 (26.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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