Guide to the Human Genome
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Search of human proteins with 18079218

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|18079218 oxysterol-binding protein-like protein 8 isoform a
[Homo sapiens]
         (889 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|18079218 oxysterol-binding protein-like protein 8 isoform a [...  1797   0.0  
gi|51243032 oxysterol-binding protein-like protein 8 isoform b [...  1716   0.0  
gi|14149740 oxysterol-binding protein-like protein 5 isoform a [...   929   0.0  
gi|221136766 oxysterol-binding protein-like protein 5 isoform b ...   724   0.0  
gi|22035609 oxysterol-binding protein-like protein 5 isoform b [...   724   0.0  
gi|20070331 oxysterol binding protein-like 9 isoform e [Homo sap...   237   4e-62
gi|22547176 oxysterol binding protein-like 9 isoform f [Homo sap...   237   4e-62
gi|22547173 oxysterol binding protein-like 9 isoform d [Homo sap...   237   4e-62
gi|22547171 oxysterol binding protein-like 9 isoform c [Homo sap...   237   4e-62
gi|22547169 oxysterol binding protein-like 9 isoform b [Homo sap...   237   4e-62
gi|22547167 oxysterol binding protein-like 9 isoform a [Homo sap...   237   4e-62
gi|22547165 oxysterol binding protein-like 9 isoform a [Homo sap...   237   4e-62
gi|19923812 oxysterol-binding protein-like protein 10 [Homo sapi...   218   3e-56
gi|19923592 oxysterol binding protein-like 11 [Homo sapiens]          213   8e-55
gi|19718746 oxysterol-binding protein-like 1A isoform A [Homo sa...   142   1e-33
gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo sa...   142   1e-33
gi|21450853 oxysterol-binding protein-like protein 2 isoform 2 [...   133   6e-31
gi|7662298 oxysterol-binding protein-like protein 2 isoform 1 [H...   133   6e-31
gi|4505531 oxysterol binding protein [Homo sapiens]                   100   8e-21
gi|22035612 oxysterol-binding protein-like protein 6 isoform b [...    98   3e-20
gi|14210532 oxysterol-binding protein-like protein 6 isoform a [...    98   3e-20
gi|22035616 oxysterol-binding protein-like protein 7 [Homo sapiens]    94   4e-19
gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens]       93   1e-18
gi|21735584 oxysterol-binding protein-like protein 3 isoform d [...    91   4e-18
gi|21735582 oxysterol-binding protein-like protein 3 isoform c [...    91   4e-18
gi|21735580 oxysterol-binding protein-like protein 3 isoform b [...    90   8e-18
gi|14149704 oxysterol-binding protein-like protein 3 isoform a [...    90   8e-18
gi|22749303 hypothetical protein LOC196477 [Homo sapiens]              47   6e-05
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    45   2e-04
gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]     44   9e-04

>gi|18079218 oxysterol-binding protein-like protein 8 isoform a
           [Homo sapiens]
          Length = 889

 Score = 1797 bits (4655), Expect = 0.0
 Identities = 889/889 (100%), Positives = 889/889 (100%)

Query: 1   MEGGLADGEPDRTSLLGDSKDVLGPSTVVANSDESQLLTPGKMSQRQGKEAYPTPTKDLH 60
           MEGGLADGEPDRTSLLGDSKDVLGPSTVVANSDESQLLTPGKMSQRQGKEAYPTPTKDLH
Sbjct: 1   MEGGLADGEPDRTSLLGDSKDVLGPSTVVANSDESQLLTPGKMSQRQGKEAYPTPTKDLH 60

Query: 61  QPSLSPASPHSQGFERGKEDISQNKDESSLSMSKSKSESKLYNGSEKDSSTSSKLTKKES 120
           QPSLSPASPHSQGFERGKEDISQNKDESSLSMSKSKSESKLYNGSEKDSSTSSKLTKKES
Sbjct: 61  QPSLSPASPHSQGFERGKEDISQNKDESSLSMSKSKSESKLYNGSEKDSSTSSKLTKKES 120

Query: 121 LKVQKKNYREEKKRATKELLSTITDPSVIVMADWLKIRGTLKSWTKLWCVLKPGVLLIYK 180
           LKVQKKNYREEKKRATKELLSTITDPSVIVMADWLKIRGTLKSWTKLWCVLKPGVLLIYK
Sbjct: 121 LKVQKKNYREEKKRATKELLSTITDPSVIVMADWLKIRGTLKSWTKLWCVLKPGVLLIYK 180

Query: 181 TQKNGQWVGTVLLNACEIIERPSKKDGFCFKLFHPLEQSIWAVKGPKGEAVGSITQPLPS 240
           TQKNGQWVGTVLLNACEIIERPSKKDGFCFKLFHPLEQSIWAVKGPKGEAVGSITQPLPS
Sbjct: 181 TQKNGQWVGTVLLNACEIIERPSKKDGFCFKLFHPLEQSIWAVKGPKGEAVGSITQPLPS 240

Query: 241 SYLIIRATSESDGRCWMDALELALKCSSLLKRTMIREGKEHDLSVSSDSTHVTFYGLLRA 300
           SYLIIRATSESDGRCWMDALELALKCSSLLKRTMIREGKEHDLSVSSDSTHVTFYGLLRA
Sbjct: 241 SYLIIRATSESDGRCWMDALELALKCSSLLKRTMIREGKEHDLSVSSDSTHVTFYGLLRA 300

Query: 301 NNLHSGDNFQLNDSEIERQHFKDQDMYSDKSDKENDQEHDESDNEVMGKSEESDTDTSER 360
           NNLHSGDNFQLNDSEIERQHFKDQDMYSDKSDKENDQEHDESDNEVMGKSEESDTDTSER
Sbjct: 301 NNLHSGDNFQLNDSEIERQHFKDQDMYSDKSDKENDQEHDESDNEVMGKSEESDTDTSER 360

Query: 361 QDDSYIEPEPVEPLKETTYTEQSHEELGEAGEASQTETVSEENKSLIWTLLKQVRPGMDL 420
           QDDSYIEPEPVEPLKETTYTEQSHEELGEAGEASQTETVSEENKSLIWTLLKQVRPGMDL
Sbjct: 361 QDDSYIEPEPVEPLKETTYTEQSHEELGEAGEASQTETVSEENKSLIWTLLKQVRPGMDL 420

Query: 421 SKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKGL 480
           SKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKGL
Sbjct: 421 SKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKGL 480

Query: 481 KKPYNPILGETFRCLWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKS 540
           KKPYNPILGETFRCLWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKS
Sbjct: 481 KKPYNPILGETFRCLWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKS 540

Query: 541 KFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTGY 600
           KFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTGY
Sbjct: 541 KFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTGY 600

Query: 601 SAILEFKLKPFLGSSDCVNQISGKLKLGKEVLATLEGHWDSEVFITDKKTDNSEVFWNPT 660
           SAILEFKLKPFLGSSDCVNQISGKLKLGKEVLATLEGHWDSEVFITDKKTDNSEVFWNPT
Sbjct: 601 SAILEFKLKPFLGSSDCVNQISGKLKLGKEVLATLEGHWDSEVFITDKKTDNSEVFWNPT 660

Query: 661 PDIKQWRLIRHTVKFEEQGDFESEKLWQRVTRAINAKDQTEATQEKYVLEEAQRQAARDR 720
           PDIKQWRLIRHTVKFEEQGDFESEKLWQRVTRAINAKDQTEATQEKYVLEEAQRQAARDR
Sbjct: 661 PDIKQWRLIRHTVKFEEQGDFESEKLWQRVTRAINAKDQTEATQEKYVLEEAQRQAARDR 720

Query: 721 KTKNEEWSCKLFELDPLTGEWHYKFADTRPWDPLNDMIQFEKDGVIQTKVKHRTPMVSVP 780
           KTKNEEWSCKLFELDPLTGEWHYKFADTRPWDPLNDMIQFEKDGVIQTKVKHRTPMVSVP
Sbjct: 721 KTKNEEWSCKLFELDPLTGEWHYKFADTRPWDPLNDMIQFEKDGVIQTKVKHRTPMVSVP 780

Query: 781 KMKHKPTRQQKKVAKGYSSPEPDIQDSSGSEAQSVKPSTRRKKGIELGDIQSSIESIKQT 840
           KMKHKPTRQQKKVAKGYSSPEPDIQDSSGSEAQSVKPSTRRKKGIELGDIQSSIESIKQT
Sbjct: 781 KMKHKPTRQQKKVAKGYSSPEPDIQDSSGSEAQSVKPSTRRKKGIELGDIQSSIESIKQT 840

Query: 841 QEEIKRNIMALRNHLVSSTPATDYFLQQKDYFIIFLLILLQVIINFMFK 889
           QEEIKRNIMALRNHLVSSTPATDYFLQQKDYFIIFLLILLQVIINFMFK
Sbjct: 841 QEEIKRNIMALRNHLVSSTPATDYFLQQKDYFIIFLLILLQVIINFMFK 889


>gi|51243032 oxysterol-binding protein-like protein 8 isoform b
           [Homo sapiens]
          Length = 847

 Score = 1716 bits (4443), Expect = 0.0
 Identities = 847/847 (100%), Positives = 847/847 (100%)

Query: 43  MSQRQGKEAYPTPTKDLHQPSLSPASPHSQGFERGKEDISQNKDESSLSMSKSKSESKLY 102
           MSQRQGKEAYPTPTKDLHQPSLSPASPHSQGFERGKEDISQNKDESSLSMSKSKSESKLY
Sbjct: 1   MSQRQGKEAYPTPTKDLHQPSLSPASPHSQGFERGKEDISQNKDESSLSMSKSKSESKLY 60

Query: 103 NGSEKDSSTSSKLTKKESLKVQKKNYREEKKRATKELLSTITDPSVIVMADWLKIRGTLK 162
           NGSEKDSSTSSKLTKKESLKVQKKNYREEKKRATKELLSTITDPSVIVMADWLKIRGTLK
Sbjct: 61  NGSEKDSSTSSKLTKKESLKVQKKNYREEKKRATKELLSTITDPSVIVMADWLKIRGTLK 120

Query: 163 SWTKLWCVLKPGVLLIYKTQKNGQWVGTVLLNACEIIERPSKKDGFCFKLFHPLEQSIWA 222
           SWTKLWCVLKPGVLLIYKTQKNGQWVGTVLLNACEIIERPSKKDGFCFKLFHPLEQSIWA
Sbjct: 121 SWTKLWCVLKPGVLLIYKTQKNGQWVGTVLLNACEIIERPSKKDGFCFKLFHPLEQSIWA 180

Query: 223 VKGPKGEAVGSITQPLPSSYLIIRATSESDGRCWMDALELALKCSSLLKRTMIREGKEHD 282
           VKGPKGEAVGSITQPLPSSYLIIRATSESDGRCWMDALELALKCSSLLKRTMIREGKEHD
Sbjct: 181 VKGPKGEAVGSITQPLPSSYLIIRATSESDGRCWMDALELALKCSSLLKRTMIREGKEHD 240

Query: 283 LSVSSDSTHVTFYGLLRANNLHSGDNFQLNDSEIERQHFKDQDMYSDKSDKENDQEHDES 342
           LSVSSDSTHVTFYGLLRANNLHSGDNFQLNDSEIERQHFKDQDMYSDKSDKENDQEHDES
Sbjct: 241 LSVSSDSTHVTFYGLLRANNLHSGDNFQLNDSEIERQHFKDQDMYSDKSDKENDQEHDES 300

Query: 343 DNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKETTYTEQSHEELGEAGEASQTETVSEE 402
           DNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKETTYTEQSHEELGEAGEASQTETVSEE
Sbjct: 301 DNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKETTYTEQSHEELGEAGEASQTETVSEE 360

Query: 403 NKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENPYFRL 462
           NKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENPYFRL
Sbjct: 361 NKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENPYFRL 420

Query: 463 KKVVKWYLSGFYKKPKGLKKPYNPILGETFRCLWIHPRTNSKTFYIAEQVSHHPPISAFY 522
           KKVVKWYLSGFYKKPKGLKKPYNPILGETFRCLWIHPRTNSKTFYIAEQVSHHPPISAFY
Sbjct: 421 KKVVKWYLSGFYKKPKGLKKPYNPILGETFRCLWIHPRTNSKTFYIAEQVSHHPPISAFY 480

Query: 523 VSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGT 582
           VSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGT
Sbjct: 481 VSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGT 540

Query: 583 MTLELGGTVNITCQKTGYSAILEFKLKPFLGSSDCVNQISGKLKLGKEVLATLEGHWDSE 642
           MTLELGGTVNITCQKTGYSAILEFKLKPFLGSSDCVNQISGKLKLGKEVLATLEGHWDSE
Sbjct: 541 MTLELGGTVNITCQKTGYSAILEFKLKPFLGSSDCVNQISGKLKLGKEVLATLEGHWDSE 600

Query: 643 VFITDKKTDNSEVFWNPTPDIKQWRLIRHTVKFEEQGDFESEKLWQRVTRAINAKDQTEA 702
           VFITDKKTDNSEVFWNPTPDIKQWRLIRHTVKFEEQGDFESEKLWQRVTRAINAKDQTEA
Sbjct: 601 VFITDKKTDNSEVFWNPTPDIKQWRLIRHTVKFEEQGDFESEKLWQRVTRAINAKDQTEA 660

Query: 703 TQEKYVLEEAQRQAARDRKTKNEEWSCKLFELDPLTGEWHYKFADTRPWDPLNDMIQFEK 762
           TQEKYVLEEAQRQAARDRKTKNEEWSCKLFELDPLTGEWHYKFADTRPWDPLNDMIQFEK
Sbjct: 661 TQEKYVLEEAQRQAARDRKTKNEEWSCKLFELDPLTGEWHYKFADTRPWDPLNDMIQFEK 720

Query: 763 DGVIQTKVKHRTPMVSVPKMKHKPTRQQKKVAKGYSSPEPDIQDSSGSEAQSVKPSTRRK 822
           DGVIQTKVKHRTPMVSVPKMKHKPTRQQKKVAKGYSSPEPDIQDSSGSEAQSVKPSTRRK
Sbjct: 721 DGVIQTKVKHRTPMVSVPKMKHKPTRQQKKVAKGYSSPEPDIQDSSGSEAQSVKPSTRRK 780

Query: 823 KGIELGDIQSSIESIKQTQEEIKRNIMALRNHLVSSTPATDYFLQQKDYFIIFLLILLQV 882
           KGIELGDIQSSIESIKQTQEEIKRNIMALRNHLVSSTPATDYFLQQKDYFIIFLLILLQV
Sbjct: 781 KGIELGDIQSSIESIKQTQEEIKRNIMALRNHLVSSTPATDYFLQQKDYFIIFLLILLQV 840

Query: 883 IINFMFK 889
           IINFMFK
Sbjct: 841 IINFMFK 847


>gi|14149740 oxysterol-binding protein-like protein 5 isoform a
           [Homo sapiens]
          Length = 879

 Score =  929 bits (2401), Expect = 0.0
 Identities = 485/892 (54%), Positives = 625/892 (70%), Gaps = 63/892 (7%)

Query: 32  SDESQLLTPGKMSQRQ----GKEAYP-TPTKDLHQPSLSPASPHSQGFERGKEDISQNKD 86
           S   Q + P K+++        E YP +P KD+ +P+  P+ P  +G             
Sbjct: 17  SSTPQKVDPRKLTRNLLLSGDNELYPLSPGKDM-EPN-GPSLPRDEG-----------PP 63

Query: 87  ESSLSMSKSKSESKLYNGSEKDS-STSSKLTKKESLKVQKKNYREEKKRATKELLSTITD 145
             S +     +E +L NGS+K+  S ++++TKKE+LK QK+NYR+EKKRAT++LLS +TD
Sbjct: 64  TPSSATKVPPAEYRLCNGSDKECVSPTARVTKKETLKAQKENYRQEKKRATRQLLSALTD 123

Query: 146 PSVIVMADWLKIRGTLKSWTKLWCVLKPGVLLIYKTQKNGQWVGTVLLNACEIIERPSKK 205
           PSV++MAD LKIRGTLKSWTKLWCVLKPGVLLIYKT K GQWVGTVLL+ CE+IERPSKK
Sbjct: 124 PSVVIMADSLKIRGTLKSWTKLWCVLKPGVLLIYKTPKVGQWVGTVLLHCCELIERPSKK 183

Query: 206 DGFCFKLFHPLEQSIWAVKGPKGEAVGSITQPLPSSYLIIRATSESDGRCWMDALELALK 265
           DGFCFKLFHPL+QS+WAVKGPKGE+VGSITQPLPSSYLI RA SESDGRCW+DALELAL+
Sbjct: 184 DGFCFKLFHPLDQSVWAVKGPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALR 243

Query: 266 CSSLLKRTMIREGKEHDLSVSSDSTHVTFYGLLRANNLHSG-DNFQLNDSEIERQHFKDQ 324
           CSSLL+    + G++ +   S D++  +  GL  +  +H   D F LN S +E       
Sbjct: 244 CSSLLRLGTCKPGRDGEPGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLEN------ 297

Query: 325 DMYSDKSDKENDQEHDESDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKE-TTYTEQS 383
           D +SDKS++EN +E D ++ +   +  ES +D SE          P  P++  TTY EQ 
Sbjct: 298 DAFSDKSERENPEESD-TETQDHSRKTESGSDQSET---------PGAPVRRGTTYVEQV 347

Query: 384 HEELGEAGEASQTETVSEENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSDYY 443
            EELGE GEASQ ETVSEENKSL+WTLLKQ+RPGMDLS+VVLPTF+LEPRSFL+KLSDYY
Sbjct: 348 QEELGELGEASQVETVSEENKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYY 407

Query: 444 YHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKGLKKPYNPILGETFRCLWIHPRTNS 503
           YHAD LS AA+EE+ Y R+K V++WYLSGFYKKPKG+KKPYNPILGETFRC W HP+T+S
Sbjct: 408 YHADLLSRAAVEEDAYSRMKLVLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDS 467

Query: 504 KTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARLTFLNRG 563
           +TFYIAEQVSHHPP+SAF+VSNRKDGFC+SGSI AKS+FYGNSLSA+L+G+A LTFLNR 
Sbjct: 468 RTFYIAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRA 527

Query: 564 EDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTGYSAILEFKLKPFLGSSDCVNQISG 623
           EDY +TMPYAHCKGILYGTMTLELGG V I C K  + A LEFKLKPF G S  +NQISG
Sbjct: 528 EDYTLTMPYAHCKGILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISG 587

Query: 624 KLKLGKEVLATLEGHWDSEVFITDKKTDNSEVFWNPTPDIKQWRLIRHTVKFEEQGDFES 683
           K+  G+EVLA+L GHWD +VFI ++ + +S +FW P+ ++++ RL +HTV  EEQ + ES
Sbjct: 588 KITSGEEVLASLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELES 647

Query: 684 EKLWQRVTRAINAKDQTEATQEKYVLEEAQRQAARDRKTKNEEWSCKLFELDPLTGEWHY 743
           E+LWQ VTRAI+  DQ  ATQEK+ LEEAQRQ AR+R+     W  +LF LDP+T EWHY
Sbjct: 648 ERLWQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLFHLDPITQEWHY 707

Query: 744 KFADTRPWDPLNDMIQFEKDGVIQT----KVKHRTPMVSVPKMKHKPTRQQKKVAKGYSS 799
           ++ D  PWDPL D+ QFE+DG+++T     V  +T  +  P  +H+ +   +++ K    
Sbjct: 708 RYEDHSPWDPLKDIAQFEQDGILRTLQQEAVARQTTFLGSPGPRHERSGPDQRLRKASDQ 767

Query: 800 PEPDIQ--DSSGSEAQSV-----------------KPSTR-RKKGIELGDIQSSIESIKQ 839
           P    Q  +SSGS  +S                   P  R RK+   L  +  +I SI++
Sbjct: 768 PSGHSQATESSGSTPESCPELSDEEQDGDFVPGGESPCPRCRKEARRLQALHEAILSIRE 827

Query: 840 TQEEIKRNIMALRNHL--VSSTPATDYFLQQKDYFIIFLLILLQVIINFMFK 889
            Q+E+ R++ A+ +     +  P        + +F++ + +  Q+ IN + K
Sbjct: 828 AQQELHRHLSAMLSSTARAAQAPTPGLLQSPRSWFLLCVFLACQLFINHILK 879


>gi|221136766 oxysterol-binding protein-like protein 5 isoform b
           [Homo sapiens]
          Length = 811

 Score =  724 bits (1870), Expect = 0.0
 Identities = 373/696 (53%), Positives = 484/696 (69%), Gaps = 44/696 (6%)

Query: 222 AVKGPKGEAVGSITQPLPSSYLIIRATSESDGRCWMDALELALKCSSLLKRTMIREGKEH 281
           ++KGPKGE+VGSITQPLPSSYLI RA SESDGRCW+DALELAL+CSSLL+    + G++ 
Sbjct: 132 SLKGPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSSLLRLGTCKPGRDG 191

Query: 282 DLSVSSDSTHVTFYGLLRANNLHSG-DNFQLNDSEIERQHFKDQDMYSDKSDKENDQEHD 340
           +   S D++  +  GL  +  +H   D F LN S +E       D +SDKS++EN +E D
Sbjct: 192 EPGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLEN------DAFSDKSERENPEESD 245

Query: 341 ESDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKE-TTYTEQSHEELGEAGEASQTETV 399
            ++ +   +  ES +D SE          P  P++  TTY EQ  EELGE GEASQ ETV
Sbjct: 246 -TETQDHSRKTESGSDQSET---------PGAPVRRGTTYVEQVQEELGELGEASQVETV 295

Query: 400 SEENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENPY 459
           SEENKSL+WTLLKQ+RPGMDLS+VVLPTF+LEPRSFL+KLSDYYYHAD LS AA+EE+ Y
Sbjct: 296 SEENKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAY 355

Query: 460 FRLKKVVKWYLSGFYKKPKGLKKPYNPILGETFRCLWIHPRTNSKTFYIAEQVSHHPPIS 519
            R+K V++WYLSGFYKKPKG+KKPYNPILGETFRC W HP+T+S+TFYIAEQVSHHPP+S
Sbjct: 356 SRMKLVLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVS 415

Query: 520 AFYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGIL 579
           AF+VSNRKDGFC+SGSI AKS+FYGNSLSA+L+G+A LTFLNR EDY +TMPYAHCKGIL
Sbjct: 416 AFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGIL 475

Query: 580 YGTMTLELGGTVNITCQKTGYSAILEFKLKPFLGSSDCVNQISGKLKLGKEVLATLEGHW 639
           YGTMTLELGG V I C K  + A LEFKLKPF G S  +NQISGK+  G+EVLA+L GHW
Sbjct: 476 YGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITSGEEVLASLSGHW 535

Query: 640 DSEVFITDKKTDNSEVFWNPTPDIKQWRLIRHTVKFEEQGDFESEKLWQRVTRAINAKDQ 699
           D +VFI ++ + +S +FW P+ ++++ RL +HTV  EEQ + ESE+LWQ VTRAI+  DQ
Sbjct: 536 DRDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRAISKGDQ 595

Query: 700 TEATQEKYVLEEAQRQAARDRKTKNEEWSCKLFELDPLTGEWHYKFADTRPWDPLNDMIQ 759
             ATQEK+ LEEAQRQ AR+R+     W  +LF LDP+T EWHY++ D  PWDPL D+ Q
Sbjct: 596 HRATQEKFALEEAQRQRARERQESLMPWKPQLFHLDPITQEWHYRYEDHSPWDPLKDIAQ 655

Query: 760 FEKDGVIQT----KVKHRTPMVSVPKMKHKPTRQQKKVAKGYSSPEPDIQ--DSSGSEAQ 813
           FE+DG+++T     V  +T  +  P  +H+ +   +++ K    P    Q  +SSGS  +
Sbjct: 656 FEQDGILRTLQQEAVARQTTFLGSPGPRHERSGPDQRLRKASDQPSGHSQATESSGSTPE 715

Query: 814 SV-----------------KPSTR-RKKGIELGDIQSSIESIKQTQEEIKRNIMALRNHL 855
           S                   P  R RK+   L  +  +I SI++ Q+E+ R++ A+ +  
Sbjct: 716 SCPELSDEEQDGDFVPGGESPCPRCRKEARRLQALHEAILSIREAQQELHRHLSAMLSST 775

Query: 856 --VSSTPATDYFLQQKDYFIIFLLILLQVIINFMFK 889
              +  P        + +F++ + +  Q+ IN + K
Sbjct: 776 ARAAQAPTPGLLQSPRSWFLLCVFLACQLFINHILK 811


>gi|22035609 oxysterol-binding protein-like protein 5 isoform b
           [Homo sapiens]
          Length = 811

 Score =  724 bits (1870), Expect = 0.0
 Identities = 373/696 (53%), Positives = 484/696 (69%), Gaps = 44/696 (6%)

Query: 222 AVKGPKGEAVGSITQPLPSSYLIIRATSESDGRCWMDALELALKCSSLLKRTMIREGKEH 281
           ++KGPKGE+VGSITQPLPSSYLI RA SESDGRCW+DALELAL+CSSLL+    + G++ 
Sbjct: 132 SLKGPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSSLLRLGTCKPGRDG 191

Query: 282 DLSVSSDSTHVTFYGLLRANNLHSG-DNFQLNDSEIERQHFKDQDMYSDKSDKENDQEHD 340
           +   S D++  +  GL  +  +H   D F LN S +E       D +SDKS++EN +E D
Sbjct: 192 EPGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLEN------DAFSDKSERENPEESD 245

Query: 341 ESDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKE-TTYTEQSHEELGEAGEASQTETV 399
            ++ +   +  ES +D SE          P  P++  TTY EQ  EELGE GEASQ ETV
Sbjct: 246 -TETQDHSRKTESGSDQSET---------PGAPVRRGTTYVEQVQEELGELGEASQVETV 295

Query: 400 SEENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENPY 459
           SEENKSL+WTLLKQ+RPGMDLS+VVLPTF+LEPRSFL+KLSDYYYHAD LS AA+EE+ Y
Sbjct: 296 SEENKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAY 355

Query: 460 FRLKKVVKWYLSGFYKKPKGLKKPYNPILGETFRCLWIHPRTNSKTFYIAEQVSHHPPIS 519
            R+K V++WYLSGFYKKPKG+KKPYNPILGETFRC W HP+T+S+TFYIAEQVSHHPP+S
Sbjct: 356 SRMKLVLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVS 415

Query: 520 AFYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGIL 579
           AF+VSNRKDGFC+SGSI AKS+FYGNSLSA+L+G+A LTFLNR EDY +TMPYAHCKGIL
Sbjct: 416 AFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGIL 475

Query: 580 YGTMTLELGGTVNITCQKTGYSAILEFKLKPFLGSSDCVNQISGKLKLGKEVLATLEGHW 639
           YGTMTLELGG V I C K  + A LEFKLKPF G S  +NQISGK+  G+EVLA+L GHW
Sbjct: 476 YGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITSGEEVLASLSGHW 535

Query: 640 DSEVFITDKKTDNSEVFWNPTPDIKQWRLIRHTVKFEEQGDFESEKLWQRVTRAINAKDQ 699
           D +VFI ++ + +S +FW P+ ++++ RL +HTV  EEQ + ESE+LWQ VTRAI+  DQ
Sbjct: 536 DRDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRAISKGDQ 595

Query: 700 TEATQEKYVLEEAQRQAARDRKTKNEEWSCKLFELDPLTGEWHYKFADTRPWDPLNDMIQ 759
             ATQEK+ LEEAQRQ AR+R+     W  +LF LDP+T EWHY++ D  PWDPL D+ Q
Sbjct: 596 HRATQEKFALEEAQRQRARERQESLMPWKPQLFHLDPITQEWHYRYEDHSPWDPLKDIAQ 655

Query: 760 FEKDGVIQT----KVKHRTPMVSVPKMKHKPTRQQKKVAKGYSSPEPDIQ--DSSGSEAQ 813
           FE+DG+++T     V  +T  +  P  +H+ +   +++ K    P    Q  +SSGS  +
Sbjct: 656 FEQDGILRTLQQEAVARQTTFLGSPGPRHERSGPDQRLRKASDQPSGHSQATESSGSTPE 715

Query: 814 SV-----------------KPSTR-RKKGIELGDIQSSIESIKQTQEEIKRNIMALRNHL 855
           S                   P  R RK+   L  +  +I SI++ Q+E+ R++ A+ +  
Sbjct: 716 SCPELSDEEQDGDFVPGGESPCPRCRKEARRLQALHEAILSIREAQQELHRHLSAMLSST 775

Query: 856 --VSSTPATDYFLQQKDYFIIFLLILLQVIINFMFK 889
              +  P        + +F++ + +  Q+ IN + K
Sbjct: 776 ARAAQAPTPGLLQSPRSWFLLCVFLACQLFINHILK 811


>gi|20070331 oxysterol binding protein-like 9 isoform e [Homo
           sapiens]
          Length = 736

 Score =  237 bits (604), Expect = 4e-62
 Identities = 161/439 (36%), Positives = 228/439 (51%), Gaps = 39/439 (8%)

Query: 327 YSDKSDK--ENDQEHDE--SDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKETTYTEQ 382
           YS   D+  + D+ H    S   ++  S  +   T     +S   P+  E L  +     
Sbjct: 288 YSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGT 347

Query: 383 SHEELGEAGEASQTETVS---EENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKL 439
           S  +L ++ +    +  +   EE+KS+I  LL QVR GMDL+KVVLPTFILE RS L+  
Sbjct: 348 SDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMY 407

Query: 440 SDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKG--LKKPYNPILGETFRCLWI 497
           +D++ H D     + +++P  R+ +VVKWYLS F+   KG   KKPYNPILGE F+C W 
Sbjct: 408 ADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWT 467

Query: 498 HPR------------------TNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAK 539
            P                    NS TF +AEQVSHHPPISAFY          +  I  K
Sbjct: 468 LPNDTEENTELVSEGPVPWVSKNSVTF-VAEQVSHHPPISAFYAECFNKKIQFNAHIWTK 526

Query: 540 SKFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTG 599
           SKF G S+     G+  ++ L+  E Y++T P  + + IL     +ELGG  NI C KTG
Sbjct: 527 SKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSIL-TVPWVELGGECNINCSKTG 585

Query: 600 YSAILEFKLKPFLGSSDCVNQISGKL--KLGKEVLATLEGHWDSEVFITDKKTDNSEVFW 657
           YSA + F  KPF G     ++I+ ++     K+   ++EG W+  V      T  + VF 
Sbjct: 586 YSANIIFHTKPFYGGKK--HRITAEIFSPNDKKSFCSIEGEWNG-VMYAKYATGENTVF- 641

Query: 658 NPTPDIKQWRLIRHTV-KFEEQGDFESEKLWQRVTRAINAKDQTEATQEKYVLEEAQRQA 716
               D K+  +I+  V K E+Q ++ES  LW+ VT  +  +D   AT+ K+ LEE QR  
Sbjct: 642 ---VDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAE 698

Query: 717 ARDRKTKNEEWSCKLFELD 735
           AR+RK K  +W  +LF  D
Sbjct: 699 ARERKEKEIQWETRLFHED 717


>gi|22547176 oxysterol binding protein-like 9 isoform f [Homo
           sapiens]
          Length = 746

 Score =  237 bits (604), Expect = 4e-62
 Identities = 161/439 (36%), Positives = 228/439 (51%), Gaps = 39/439 (8%)

Query: 327 YSDKSDK--ENDQEHDE--SDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKETTYTEQ 382
           YS   D+  + D+ H    S   ++  S  +   T     +S   P+  E L  +     
Sbjct: 298 YSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGT 357

Query: 383 SHEELGEAGEASQTETVS---EENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKL 439
           S  +L ++ +    +  +   EE+KS+I  LL QVR GMDL+KVVLPTFILE RS L+  
Sbjct: 358 SDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMY 417

Query: 440 SDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKG--LKKPYNPILGETFRCLWI 497
           +D++ H D     + +++P  R+ +VVKWYLS F+   KG   KKPYNPILGE F+C W 
Sbjct: 418 ADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWT 477

Query: 498 HPR------------------TNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAK 539
            P                    NS TF +AEQVSHHPPISAFY          +  I  K
Sbjct: 478 LPNDTEENTELVSEGPVPWVSKNSVTF-VAEQVSHHPPISAFYAECFNKKIQFNAHIWTK 536

Query: 540 SKFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTG 599
           SKF G S+     G+  ++ L+  E Y++T P  + + IL     +ELGG  NI C KTG
Sbjct: 537 SKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSIL-TVPWVELGGECNINCSKTG 595

Query: 600 YSAILEFKLKPFLGSSDCVNQISGKL--KLGKEVLATLEGHWDSEVFITDKKTDNSEVFW 657
           YSA + F  KPF G     ++I+ ++     K+   ++EG W+  V      T  + VF 
Sbjct: 596 YSANIIFHTKPFYGGKK--HRITAEIFSPNDKKSFCSIEGEWNG-VMYAKYATGENTVF- 651

Query: 658 NPTPDIKQWRLIRHTV-KFEEQGDFESEKLWQRVTRAINAKDQTEATQEKYVLEEAQRQA 716
               D K+  +I+  V K E+Q ++ES  LW+ VT  +  +D   AT+ K+ LEE QR  
Sbjct: 652 ---VDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAE 708

Query: 717 ARDRKTKNEEWSCKLFELD 735
           AR+RK K  +W  +LF  D
Sbjct: 709 ARERKEKEIQWETRLFHED 727


>gi|22547173 oxysterol binding protein-like 9 isoform d [Homo
           sapiens]
          Length = 723

 Score =  237 bits (604), Expect = 4e-62
 Identities = 161/439 (36%), Positives = 228/439 (51%), Gaps = 39/439 (8%)

Query: 327 YSDKSDK--ENDQEHDE--SDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKETTYTEQ 382
           YS   D+  + D+ H    S   ++  S  +   T     +S   P+  E L  +     
Sbjct: 275 YSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGT 334

Query: 383 SHEELGEAGEASQTETVS---EENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKL 439
           S  +L ++ +    +  +   EE+KS+I  LL QVR GMDL+KVVLPTFILE RS L+  
Sbjct: 335 SDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMY 394

Query: 440 SDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKG--LKKPYNPILGETFRCLWI 497
           +D++ H D     + +++P  R+ +VVKWYLS F+   KG   KKPYNPILGE F+C W 
Sbjct: 395 ADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWT 454

Query: 498 HPR------------------TNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAK 539
            P                    NS TF +AEQVSHHPPISAFY          +  I  K
Sbjct: 455 LPNDTEENTELVSEGPVPWVSKNSVTF-VAEQVSHHPPISAFYAECFNKKIQFNAHIWTK 513

Query: 540 SKFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTG 599
           SKF G S+     G+  ++ L+  E Y++T P  + + IL     +ELGG  NI C KTG
Sbjct: 514 SKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSIL-TVPWVELGGECNINCSKTG 572

Query: 600 YSAILEFKLKPFLGSSDCVNQISGKL--KLGKEVLATLEGHWDSEVFITDKKTDNSEVFW 657
           YSA + F  KPF G     ++I+ ++     K+   ++EG W+  V      T  + VF 
Sbjct: 573 YSANIIFHTKPFYGGKK--HRITAEIFSPNDKKSFCSIEGEWNG-VMYAKYATGENTVF- 628

Query: 658 NPTPDIKQWRLIRHTV-KFEEQGDFESEKLWQRVTRAINAKDQTEATQEKYVLEEAQRQA 716
               D K+  +I+  V K E+Q ++ES  LW+ VT  +  +D   AT+ K+ LEE QR  
Sbjct: 629 ---VDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAE 685

Query: 717 ARDRKTKNEEWSCKLFELD 735
           AR+RK K  +W  +LF  D
Sbjct: 686 ARERKEKEIQWETRLFHED 704


>gi|22547171 oxysterol binding protein-like 9 isoform c [Homo
           sapiens]
          Length = 626

 Score =  237 bits (604), Expect = 4e-62
 Identities = 161/439 (36%), Positives = 228/439 (51%), Gaps = 39/439 (8%)

Query: 327 YSDKSDK--ENDQEHDE--SDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKETTYTEQ 382
           YS   D+  + D+ H    S   ++  S  +   T     +S   P+  E L  +     
Sbjct: 178 YSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGT 237

Query: 383 SHEELGEAGEASQTETVS---EENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKL 439
           S  +L ++ +    +  +   EE+KS+I  LL QVR GMDL+KVVLPTFILE RS L+  
Sbjct: 238 SDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMY 297

Query: 440 SDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKG--LKKPYNPILGETFRCLWI 497
           +D++ H D     + +++P  R+ +VVKWYLS F+   KG   KKPYNPILGE F+C W 
Sbjct: 298 ADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWT 357

Query: 498 HPR------------------TNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAK 539
            P                    NS TF +AEQVSHHPPISAFY          +  I  K
Sbjct: 358 LPNDTEENTELVSEGPVPWVSKNSVTF-VAEQVSHHPPISAFYAECFNKKIQFNAHIWTK 416

Query: 540 SKFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTG 599
           SKF G S+     G+  ++ L+  E Y++T P  + + IL     +ELGG  NI C KTG
Sbjct: 417 SKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSIL-TVPWVELGGECNINCSKTG 475

Query: 600 YSAILEFKLKPFLGSSDCVNQISGKL--KLGKEVLATLEGHWDSEVFITDKKTDNSEVFW 657
           YSA + F  KPF G     ++I+ ++     K+   ++EG W+  V      T  + VF 
Sbjct: 476 YSANIIFHTKPFYGGKK--HRITAEIFSPNDKKSFCSIEGEWNG-VMYAKYATGENTVF- 531

Query: 658 NPTPDIKQWRLIRHTV-KFEEQGDFESEKLWQRVTRAINAKDQTEATQEKYVLEEAQRQA 716
               D K+  +I+  V K E+Q ++ES  LW+ VT  +  +D   AT+ K+ LEE QR  
Sbjct: 532 ---VDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAE 588

Query: 717 ARDRKTKNEEWSCKLFELD 735
           AR+RK K  +W  +LF  D
Sbjct: 589 ARERKEKEIQWETRLFHED 607


>gi|22547169 oxysterol binding protein-like 9 isoform b [Homo
           sapiens]
          Length = 571

 Score =  237 bits (604), Expect = 4e-62
 Identities = 161/439 (36%), Positives = 228/439 (51%), Gaps = 39/439 (8%)

Query: 327 YSDKSDK--ENDQEHDE--SDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKETTYTEQ 382
           YS   D+  + D+ H    S   ++  S  +   T     +S   P+  E L  +     
Sbjct: 123 YSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGT 182

Query: 383 SHEELGEAGEASQTETVS---EENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKL 439
           S  +L ++ +    +  +   EE+KS+I  LL QVR GMDL+KVVLPTFILE RS L+  
Sbjct: 183 SDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMY 242

Query: 440 SDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKG--LKKPYNPILGETFRCLWI 497
           +D++ H D     + +++P  R+ +VVKWYLS F+   KG   KKPYNPILGE F+C W 
Sbjct: 243 ADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWT 302

Query: 498 HPR------------------TNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAK 539
            P                    NS TF +AEQVSHHPPISAFY          +  I  K
Sbjct: 303 LPNDTEENTELVSEGPVPWVSKNSVTF-VAEQVSHHPPISAFYAECFNKKIQFNAHIWTK 361

Query: 540 SKFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTG 599
           SKF G S+     G+  ++ L+  E Y++T P  + + IL     +ELGG  NI C KTG
Sbjct: 362 SKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSIL-TVPWVELGGECNINCSKTG 420

Query: 600 YSAILEFKLKPFLGSSDCVNQISGKL--KLGKEVLATLEGHWDSEVFITDKKTDNSEVFW 657
           YSA + F  KPF G     ++I+ ++     K+   ++EG W+  V      T  + VF 
Sbjct: 421 YSANIIFHTKPFYGGKK--HRITAEIFSPNDKKSFCSIEGEWNG-VMYAKYATGENTVF- 476

Query: 658 NPTPDIKQWRLIRHTV-KFEEQGDFESEKLWQRVTRAINAKDQTEATQEKYVLEEAQRQA 716
               D K+  +I+  V K E+Q ++ES  LW+ VT  +  +D   AT+ K+ LEE QR  
Sbjct: 477 ---VDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAE 533

Query: 717 ARDRKTKNEEWSCKLFELD 735
           AR+RK K  +W  +LF  D
Sbjct: 534 ARERKEKEIQWETRLFHED 552


>gi|22547167 oxysterol binding protein-like 9 isoform a [Homo
           sapiens]
          Length = 558

 Score =  237 bits (604), Expect = 4e-62
 Identities = 161/439 (36%), Positives = 228/439 (51%), Gaps = 39/439 (8%)

Query: 327 YSDKSDK--ENDQEHDE--SDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKETTYTEQ 382
           YS   D+  + D+ H    S   ++  S  +   T     +S   P+  E L  +     
Sbjct: 110 YSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGT 169

Query: 383 SHEELGEAGEASQTETVS---EENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKL 439
           S  +L ++ +    +  +   EE+KS+I  LL QVR GMDL+KVVLPTFILE RS L+  
Sbjct: 170 SDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMY 229

Query: 440 SDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKG--LKKPYNPILGETFRCLWI 497
           +D++ H D     + +++P  R+ +VVKWYLS F+   KG   KKPYNPILGE F+C W 
Sbjct: 230 ADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWT 289

Query: 498 HPR------------------TNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAK 539
            P                    NS TF +AEQVSHHPPISAFY          +  I  K
Sbjct: 290 LPNDTEENTELVSEGPVPWVSKNSVTF-VAEQVSHHPPISAFYAECFNKKIQFNAHIWTK 348

Query: 540 SKFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTG 599
           SKF G S+     G+  ++ L+  E Y++T P  + + IL     +ELGG  NI C KTG
Sbjct: 349 SKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSIL-TVPWVELGGECNINCSKTG 407

Query: 600 YSAILEFKLKPFLGSSDCVNQISGKL--KLGKEVLATLEGHWDSEVFITDKKTDNSEVFW 657
           YSA + F  KPF G     ++I+ ++     K+   ++EG W+  V      T  + VF 
Sbjct: 408 YSANIIFHTKPFYGGKK--HRITAEIFSPNDKKSFCSIEGEWNG-VMYAKYATGENTVF- 463

Query: 658 NPTPDIKQWRLIRHTV-KFEEQGDFESEKLWQRVTRAINAKDQTEATQEKYVLEEAQRQA 716
               D K+  +I+  V K E+Q ++ES  LW+ VT  +  +D   AT+ K+ LEE QR  
Sbjct: 464 ---VDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAE 520

Query: 717 ARDRKTKNEEWSCKLFELD 735
           AR+RK K  +W  +LF  D
Sbjct: 521 ARERKEKEIQWETRLFHED 539


>gi|22547165 oxysterol binding protein-like 9 isoform a [Homo
           sapiens]
          Length = 558

 Score =  237 bits (604), Expect = 4e-62
 Identities = 161/439 (36%), Positives = 228/439 (51%), Gaps = 39/439 (8%)

Query: 327 YSDKSDK--ENDQEHDE--SDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKETTYTEQ 382
           YS   D+  + D+ H    S   ++  S  +   T     +S   P+  E L  +     
Sbjct: 110 YSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGT 169

Query: 383 SHEELGEAGEASQTETVS---EENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKL 439
           S  +L ++ +    +  +   EE+KS+I  LL QVR GMDL+KVVLPTFILE RS L+  
Sbjct: 170 SDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMY 229

Query: 440 SDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKG--LKKPYNPILGETFRCLWI 497
           +D++ H D     + +++P  R+ +VVKWYLS F+   KG   KKPYNPILGE F+C W 
Sbjct: 230 ADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWT 289

Query: 498 HPR------------------TNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAK 539
            P                    NS TF +AEQVSHHPPISAFY          +  I  K
Sbjct: 290 LPNDTEENTELVSEGPVPWVSKNSVTF-VAEQVSHHPPISAFYAECFNKKIQFNAHIWTK 348

Query: 540 SKFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTG 599
           SKF G S+     G+  ++ L+  E Y++T P  + + IL     +ELGG  NI C KTG
Sbjct: 349 SKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSIL-TVPWVELGGECNINCSKTG 407

Query: 600 YSAILEFKLKPFLGSSDCVNQISGKL--KLGKEVLATLEGHWDSEVFITDKKTDNSEVFW 657
           YSA + F  KPF G     ++I+ ++     K+   ++EG W+  V      T  + VF 
Sbjct: 408 YSANIIFHTKPFYGGKK--HRITAEIFSPNDKKSFCSIEGEWNG-VMYAKYATGENTVF- 463

Query: 658 NPTPDIKQWRLIRHTV-KFEEQGDFESEKLWQRVTRAINAKDQTEATQEKYVLEEAQRQA 716
               D K+  +I+  V K E+Q ++ES  LW+ VT  +  +D   AT+ K+ LEE QR  
Sbjct: 464 ---VDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAE 520

Query: 717 ARDRKTKNEEWSCKLFELD 735
           AR+RK K  +W  +LF  D
Sbjct: 521 ARERKEKEIQWETRLFHED 539


>gi|19923812 oxysterol-binding protein-like protein 10 [Homo
           sapiens]
          Length = 764

 Score =  218 bits (554), Expect = 3e-56
 Identities = 144/408 (35%), Positives = 207/408 (50%), Gaps = 43/408 (10%)

Query: 356 DTSERQDDSYIEPEPVEPLKETTYTEQSHEELGEAGEASQTET-VSEENKSLIWTLLKQV 414
           +++E +  S  EPEP       +    S +E  +  +  +TE  V E+ +S+I  L+ Q+
Sbjct: 352 NSAEDEQTSQPEPEP----NSGSELVLSEDEKSDNEDKEETELGVMEDQRSIILHLISQL 407

Query: 415 RPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFY 474
           + GMDL+KVVLPTFILE RS L+  +D+  H D L        P  R+   V++YL+ F+
Sbjct: 408 KLGMDLTKVVLPTFILEKRSLLEMYADFMAHPDLLLAITAGATPEERVICFVEYYLTAFH 467

Query: 475 KKPKGL--KKPYNPILGETFRCLWIHPRTN-----------------------SKTF--- 506
           +  KG   KKPYNPI+GETF C W  P+                         SK++   
Sbjct: 468 EGRKGALAKKPYNPIIGETFHCSWEVPKDRVKPKRTASRSPASCHEHPMADDPSKSYKLR 527

Query: 507 YIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARLTFLNRGEDY 566
           ++AEQVSHHPPIS FY    +   C++  +  KSKF G S+   + GE  L  L  GE+Y
Sbjct: 528 FVAEQVSHHPPISCFYCECEEKRLCVNTHVWTKSKFMGMSVGVSMIGEGVLRLLEHGEEY 587

Query: 567 VMTMPYAHCKGILYGTMTLELGGTVNITCQKTGYSAILEFKLKPFLGSSDCVNQISGKLK 626
           V T+P A+ + IL     +ELGG V+I C KTGYSA + F  KPF G    V++++ ++K
Sbjct: 588 VFTLPSAYARSIL-TIPWVELGGKVSINCAKTGYSATVIFHTKPFYGGK--VHRVTAEVK 644

Query: 627 LG--KEVLATLEGHWDSEVFITDKKTDNSEVFWNPTPDIKQWRLIRHTVKFEEQGDFESE 684
                 ++    G W+  +  T    +   +     P     + IR     E+QG  ES 
Sbjct: 645 HNPTNTIVCKAHGEWNGTLEFTYNNGETKVIDTTTLPVYP--KKIR---PLEKQGPMESR 699

Query: 685 KLWQRVTRAINAKDQTEATQEKYVLEEAQRQAARDRKTKNEEWSCKLF 732
            LW+ VTR +   D   AT++K  LEE QR   R R+     W  K F
Sbjct: 700 NLWREVTRYLRLGDIDAATEQKRHLEEKQRVEERKRENLRTPWKPKYF 747


>gi|19923592 oxysterol binding protein-like 11 [Homo sapiens]
          Length = 747

 Score =  213 bits (541), Expect = 8e-55
 Identities = 133/405 (32%), Positives = 204/405 (50%), Gaps = 53/405 (13%)

Query: 372 EPLKETTYTEQSHEELGEAGEASQTET-------VSEENKSLIWTLLKQVRPGMDLSKVV 424
           +P+ E+    +  EE+    E   T           EE +S+I  LL Q++ GMDL++VV
Sbjct: 328 QPVAESGLLAREPEEINADDEIEDTCDHKEDDLGAVEEQRSVILHLLSQLKLGMDLTRVV 387

Query: 425 LPTFILEPRSFLDKLSDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKGL--KK 482
           LPTFILE RS L+  +D+  H D             R+ + V++YL+ F++  KG   KK
Sbjct: 388 LPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHEGRKGAIAKK 447

Query: 483 PYNPILGETFRCLWIHPRTN--SKTF------------------------------YIAE 510
           PYNPI+GETF C W  P++   S  F                              ++AE
Sbjct: 448 PYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQVGSDCYTVRFVAE 507

Query: 511 QVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARLTFLNRGEDYVMTM 570
           QVSHHPP+S FY    +   C++  +  KSKF G S+   + GE  L+ L  GE+Y  ++
Sbjct: 508 QVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLEHGEEYTFSL 567

Query: 571 PYAHCKGILYGTMTLELGGTVNITCQKTGYSAILEFKLKPFLGSSDCVNQISGKLK--LG 628
           P A+ + IL     +ELGG V++ C KTGYSA + F  KPF G    +++++ ++K  + 
Sbjct: 568 PCAYARSIL-TVPWVELGGKVSVNCAKTGYSASITFHTKPFYGGK--LHRVTAEVKHNIT 624

Query: 629 KEVLATLEGHWDSEVFITDKKTDNSEVFWNPTPDIKQWRLIRHTVK-FEEQGDFESEKLW 687
             V+  ++G W+S +  T    +   V      D+ +  + +  V+  E+Q  FES +LW
Sbjct: 625 NTVVCRVQGEWNSVLEFTYSNGETKYV------DLTKLAVTKKRVRPLEKQDPFESRRLW 678

Query: 688 QRVTRAINAKDQTEATQEKYVLEEAQRQAARDRKTKNEEWSCKLF 732
           + VT ++   +  +AT+ K+ LEE QR   R R      W  K F
Sbjct: 679 KNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETGTPWKTKYF 723


>gi|19718746 oxysterol-binding protein-like 1A isoform A [Homo
           sapiens]
          Length = 437

 Score =  142 bits (359), Expect = 1e-33
 Identities = 112/386 (29%), Positives = 171/386 (44%), Gaps = 59/386 (15%)

Query: 403 NKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENPYFRL 462
           N   IW++L++   GM+LSK+ +P    EP SFL +L++Y  H   + +A+   +P  R+
Sbjct: 32  NDFSIWSILRKCI-GMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERM 90

Query: 463 KKVVKWYLSGFYKKPKGLKKPYNPILGETFRCLWIHPRTNSKTFYIAEQVSHHPPISAFY 522
           + V  + +S    + +   KP+NP+LGET+  +    R +     I+EQVSHHPPISAF+
Sbjct: 91  QCVAAFAVSAVASQWERTGKPFNPLLGETYELV----RDDLGFRLISEQVSHHPPISAFH 146

Query: 523 VSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGT 582
                + F   GSI  K KF+G S+ A  +G   L  L   E Y  T P      I+ G 
Sbjct: 147 AEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGK 206

Query: 583 MTLELGGTVNITCQKTGYSAILEFKLKPFLGSSDCVNQISGKLK-LGKEVLATLEGHW-- 639
           + +E  G V I   KTG   +L FK     G    ++++ G ++   K+ L  L G W  
Sbjct: 207 LWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKE--LHKVEGYIQDKSKKKLCALYGKWTE 264

Query: 640 -----DSEVFITDKKTD---------------NSEVFWNPTPD----------IKQWRLI 669
                D   F   KK D               + E+   P PD          +  WR+ 
Sbjct: 265 CLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVLLWRIA 324

Query: 670 RHTVKFEEQGDF--------ESEKLWQRV-----------TRAINAKDQTEATQEKYVLE 710
                  +  +F        E +K  + V            RA+   +  +A++EK  LE
Sbjct: 325 PRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKRLE 384

Query: 711 EAQRQAARDRKTKNEEWSCKLFELDP 736
           E QR A ++R    E+W  + F   P
Sbjct: 385 EKQRAARKNRSKSEEDWKTRWFHQGP 410


>gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo
           sapiens]
          Length = 950

 Score =  142 bits (359), Expect = 1e-33
 Identities = 112/386 (29%), Positives = 171/386 (44%), Gaps = 59/386 (15%)

Query: 403 NKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENPYFRL 462
           N   IW++L++   GM+LSK+ +P    EP SFL +L++Y  H   + +A+   +P  R+
Sbjct: 545 NDFSIWSILRKCI-GMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERM 603

Query: 463 KKVVKWYLSGFYKKPKGLKKPYNPILGETFRCLWIHPRTNSKTFYIAEQVSHHPPISAFY 522
           + V  + +S    + +   KP+NP+LGET+  +    R +     I+EQVSHHPPISAF+
Sbjct: 604 QCVAAFAVSAVASQWERTGKPFNPLLGETYELV----RDDLGFRLISEQVSHHPPISAFH 659

Query: 523 VSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGT 582
                + F   GSI  K KF+G S+ A  +G   L  L   E Y  T P      I+ G 
Sbjct: 660 AEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGK 719

Query: 583 MTLELGGTVNITCQKTGYSAILEFKLKPFLGSSDCVNQISGKLK-LGKEVLATLEGHW-- 639
           + +E  G V I   KTG   +L FK     G    ++++ G ++   K+ L  L G W  
Sbjct: 720 LWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKE--LHKVEGYIQDKSKKKLCALYGKWTE 777

Query: 640 -----DSEVFITDKKTD---------------NSEVFWNPTPD----------IKQWRLI 669
                D   F   KK D               + E+   P PD          +  WR+ 
Sbjct: 778 CLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVLLWRIA 837

Query: 670 RHTVKFEEQGDF--------ESEKLWQRV-----------TRAINAKDQTEATQEKYVLE 710
                  +  +F        E +K  + V            RA+   +  +A++EK  LE
Sbjct: 838 PRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKRLE 897

Query: 711 EAQRQAARDRKTKNEEWSCKLFELDP 736
           E QR A ++R    E+W  + F   P
Sbjct: 898 EKQRAARKNRSKSEEDWKTRWFHQGP 923


>gi|21450853 oxysterol-binding protein-like protein 2 isoform 2
           [Homo sapiens]
          Length = 480

 Score =  133 bits (335), Expect = 6e-31
 Identities = 84/269 (31%), Positives = 134/269 (49%), Gaps = 20/269 (7%)

Query: 384 HEELGEAGEA-SQTETVSEENKSL-----------IWTLLKQVRPGMDLSKVVLPTFILE 431
           +  +G+ GE  SQ   + +   SL           +WT+LK+   G++LSK+ +P    E
Sbjct: 41  NNRIGKTGERPSQENGIQKHRTSLPAPMFSRSDFSVWTILKKC-VGLELSKITMPIAFNE 99

Query: 432 PRSFLDKLSDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKGLKKPYNPILGET 491
           P SFL ++++Y  H   +  A+ +  P  R++ V  + +S    + +   KP+NP+LGET
Sbjct: 100 PLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGET 159

Query: 492 FRCLWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAIL 551
           +  +    R +    +I+EQVSHHPPISAF+       F   GSI  K KF+G S+ A  
Sbjct: 160 YELI----REDLGFRFISEQVSHHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEP 215

Query: 552 EGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTGYSAILEFKLKPF 611
            G   L  L   E Y  T P      ++ G + +E  GTV I   +TG+  +L FK    
Sbjct: 216 RGTITLELLKHNEAYTWTNPTCCVHNVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGL 275

Query: 612 LGSSDCVNQISGKLK-LGKEVLATLEGHW 639
            G    ++++ G ++   K+ L  + G W
Sbjct: 276 FGKE--LHKVEGHIQDKNKKKLFMIYGKW 302



 Score = 34.7 bits (78), Expect = 0.40
 Identities = 20/46 (43%), Positives = 27/46 (58%), Gaps = 4/46 (8%)

Query: 702 ATQEKYVLEEAQRQAARDRKTKNEEWSCKLF--ELDPLTG--EWHY 743
           A+QEK  LEE QR+A R+R  +  EW  + F    +P TG  +W Y
Sbjct: 419 ASQEKERLEEKQREARRERAKEEAEWQTRWFYPGNNPYTGTPDWLY 464


>gi|7662298 oxysterol-binding protein-like protein 2 isoform 1 [Homo
           sapiens]
          Length = 468

 Score =  133 bits (335), Expect = 6e-31
 Identities = 84/269 (31%), Positives = 134/269 (49%), Gaps = 20/269 (7%)

Query: 384 HEELGEAGEA-SQTETVSEENKSL-----------IWTLLKQVRPGMDLSKVVLPTFILE 431
           +  +G+ GE  SQ   + +   SL           +WT+LK+   G++LSK+ +P    E
Sbjct: 29  NNRIGKTGERPSQENGIQKHRTSLPAPMFSRSDFSVWTILKKC-VGLELSKITMPIAFNE 87

Query: 432 PRSFLDKLSDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKGLKKPYNPILGET 491
           P SFL ++++Y  H   +  A+ +  P  R++ V  + +S    + +   KP+NP+LGET
Sbjct: 88  PLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGET 147

Query: 492 FRCLWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAIL 551
           +  +    R +    +I+EQVSHHPPISAF+       F   GSI  K KF+G S+ A  
Sbjct: 148 YELI----REDLGFRFISEQVSHHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEP 203

Query: 552 EGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTGYSAILEFKLKPF 611
            G   L  L   E Y  T P      ++ G + +E  GTV I   +TG+  +L FK    
Sbjct: 204 RGTITLELLKHNEAYTWTNPTCCVHNVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGL 263

Query: 612 LGSSDCVNQISGKLK-LGKEVLATLEGHW 639
            G    ++++ G ++   K+ L  + G W
Sbjct: 264 FGKE--LHKVEGHIQDKNKKKLFMIYGKW 290



 Score = 34.7 bits (78), Expect = 0.40
 Identities = 20/46 (43%), Positives = 27/46 (58%), Gaps = 4/46 (8%)

Query: 702 ATQEKYVLEEAQRQAARDRKTKNEEWSCKLF--ELDPLTG--EWHY 743
           A+QEK  LEE QR+A R+R  +  EW  + F    +P TG  +W Y
Sbjct: 407 ASQEKERLEEKQREARRERAKEEAEWQTRWFYPGNNPYTGTPDWLY 452


>gi|4505531 oxysterol binding protein [Homo sapiens]
          Length = 807

 Score =  100 bits (248), Expect = 8e-21
 Identities = 103/393 (26%), Positives = 167/393 (42%), Gaps = 33/393 (8%)

Query: 381 EQSHEELGEAGEASQTETVSEENKSL-IWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKL 439
           EQ   +L E  +  +T    + N SL +W+++K    G +LSK+ +P    EP S L +L
Sbjct: 392 EQYKHQLEETKKEKRTRIPYKPNYSLNLWSIMKNCI-GKELSKIPMPVNFNEPLSMLQRL 450

Query: 440 SDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKGLKKPYNPILGETFRCLWIHP 499
           ++   + + L  AA  EN   +L  V  + +S +        KP+NP+LGETF    +  
Sbjct: 451 TEDLEYHELLDRAAKCENSLEQLCYVAAFTVSSYSTTVFRTSKPFNPLLGETFE---LDR 507

Query: 500 RTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARLTF 559
              +    + EQVSHHPP +A +  + K+G+ L   I   SKF G  LS +  G     F
Sbjct: 508 LEENGYRSLCEQVSHHPPAAAHHAES-KNGWTLRQEIKITSKFRGKYLSIMPLGTIHCIF 566

Query: 560 LNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTGYSAILEFKLKPFLGSSDCVN 619
              G  Y           I+ G + ++  G ++I   KTG    L+F    +  S D   
Sbjct: 567 HATGHHYTWKKVTTTVHNIIVGKLWIDQSGEIDIVNHKTGDKCNLKFVPYSYF-SRDVAR 625

Query: 620 QISGKL--KLGKEVLATLEGHWDS--EVFITD---------------KKTDNSEVFW--N 658
           +++G++    GK   A L G WD   E F                  +  ++  + W  N
Sbjct: 626 KVTGEVTDPSGKVHFALL-GTWDEKMECFKVQPVIGENGGDARQRGHEAEESRVMLWKRN 684

Query: 659 PTP----DIKQWRLIRHTVKFEEQGDFESEKLWQRVTRAINAKDQTEATQEKYVLEEAQR 714
           P P    ++  +  +  T+   E G   ++   +   R +      EA  EK  LEE QR
Sbjct: 685 PLPKNAENMYYFSELALTLNAWESGTAPTDSRLRPDQRLMENGRWDEANAEKQRLEEKQR 744

Query: 715 QAARDRKTKNEEWSCKLFELDPLTGEWHYKFAD 747
            + + R+ +  + +      DP    W  +  D
Sbjct: 745 LSRKKREAEAMKATEDGTPYDPYKALWFERKKD 777


>gi|22035612 oxysterol-binding protein-like protein 6 isoform b
           [Homo sapiens]
          Length = 938

 Score = 98.2 bits (243), Expect = 3e-20
 Identities = 109/438 (24%), Positives = 183/438 (41%), Gaps = 37/438 (8%)

Query: 310 QLNDSEIERQHFKDQDMYSDKSDKENDQEHDESDNEVMGKSEESDTDTSERQDDSYIEPE 369
           +L+ SE   + F  Q++    S  EN+   DES          SD   +  +D++ +   
Sbjct: 489 RLSMSESVSEFFDAQEVLLSASSSENEASDDES--------YISDVSDNISEDNTSVADN 540

Query: 370 PVEPLKETTYTEQSHEELGEAGEASQTETVSEENKSLIWTLLKQVRPGMDLSKVVLPTFI 429
               +     T  +      A   +     S  N   +W +L+    G DLSKV +P  +
Sbjct: 541 ISRQILNGELTGGAFRNGRRACLPAPCPDTSNIN---LWNILRN-NIGKDLSKVSMPVEL 596

Query: 430 LEPRSFLDKLSDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKP-KGLKKPYNPIL 488
            EP + L  L +   +++ L +A+  ++PY R+  V  + +SG+     +   KP+NP+L
Sbjct: 597 NEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVL 656

Query: 489 GETFRCLWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLS 548
           GET+ C+    R +    + +EQVSHHPPISA +  ++   F     I  K+KF+G S+ 
Sbjct: 657 GETYECI----REDKGFRFFSEQVSHHPPISACHCESK--NFVFWQDIRWKNKFWGKSME 710

Query: 549 AILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTGYSAI-LEFK 607
            +  G   +     G+ YV          IL G   +E  G V I   K+      L F 
Sbjct: 711 ILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFV 770

Query: 608 LKPFLGSSDCVNQISGKL--KLGKEVLATLEGHWDSEVFITDKKTDNSEVFWNPTPDIKQ 665
              +  S+  +N++ G +  + GK V   L G W   ++       +++  W P      
Sbjct: 771 KVNYWNSN--MNEVQGVVIDQEGKAVY-RLFGKWHEGLYC--GVAPSAKCIWRPGSMPTN 825

Query: 666 WRL----IRHTVKFEEQGDFESEKL------WQRVTRAINAKDQTEATQEKYVLEEAQRQ 715
           + L     R  ++  E      + L      ++   R +   +   A  EK  +EE QR 
Sbjct: 826 YELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRS 885

Query: 716 AARDRKTKNEEWSCKLFE 733
             R  +  N E   K F+
Sbjct: 886 RRRYMEENNLEHIPKFFK 903


>gi|14210532 oxysterol-binding protein-like protein 6 isoform a
           [Homo sapiens]
          Length = 934

 Score = 98.2 bits (243), Expect = 3e-20
 Identities = 109/438 (24%), Positives = 183/438 (41%), Gaps = 37/438 (8%)

Query: 310 QLNDSEIERQHFKDQDMYSDKSDKENDQEHDESDNEVMGKSEESDTDTSERQDDSYIEPE 369
           +L+ SE   + F  Q++    S  EN+   DES          SD   +  +D++ +   
Sbjct: 485 RLSMSESVSEFFDAQEVLLSASSSENEASDDES--------YISDVSDNISEDNTSVADN 536

Query: 370 PVEPLKETTYTEQSHEELGEAGEASQTETVSEENKSLIWTLLKQVRPGMDLSKVVLPTFI 429
               +     T  +      A   +     S  N   +W +L+    G DLSKV +P  +
Sbjct: 537 ISRQILNGELTGGAFRNGRRACLPAPCPDTSNIN---LWNILRN-NIGKDLSKVSMPVEL 592

Query: 430 LEPRSFLDKLSDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKP-KGLKKPYNPIL 488
            EP + L  L +   +++ L +A+  ++PY R+  V  + +SG+     +   KP+NP+L
Sbjct: 593 NEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVL 652

Query: 489 GETFRCLWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLS 548
           GET+ C+    R +    + +EQVSHHPPISA +  ++   F     I  K+KF+G S+ 
Sbjct: 653 GETYECI----REDKGFRFFSEQVSHHPPISACHCESK--NFVFWQDIRWKNKFWGKSME 706

Query: 549 AILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTGYSAI-LEFK 607
            +  G   +     G+ YV          IL G   +E  G V I   K+      L F 
Sbjct: 707 ILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFV 766

Query: 608 LKPFLGSSDCVNQISGKL--KLGKEVLATLEGHWDSEVFITDKKTDNSEVFWNPTPDIKQ 665
              +  S+  +N++ G +  + GK V   L G W   ++       +++  W P      
Sbjct: 767 KVNYWNSN--MNEVQGVVIDQEGKAVY-RLFGKWHEGLYC--GVAPSAKCIWRPGSMPTN 821

Query: 666 WRL----IRHTVKFEEQGDFESEKL------WQRVTRAINAKDQTEATQEKYVLEEAQRQ 715
           + L     R  ++  E      + L      ++   R +   +   A  EK  +EE QR 
Sbjct: 822 YELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRS 881

Query: 716 AARDRKTKNEEWSCKLFE 733
             R  +  N E   K F+
Sbjct: 882 RRRYMEENNLEHIPKFFK 899


>gi|22035616 oxysterol-binding protein-like protein 7 [Homo sapiens]
          Length = 842

 Score = 94.4 bits (233), Expect = 4e-19
 Identities = 117/470 (24%), Positives = 190/470 (40%), Gaps = 61/470 (12%)

Query: 281 HDLSVSSDSTHVTFYGLLRANN-------------LHSGDNFQLNDSEIERQHFKDQDMY 327
           H LS SSD+T  +F  L                  L       L DS  E     +  + 
Sbjct: 353 HSLSTSSDTTADSFSSLNPEEQEALYMKGRELTPQLSQTSILSLADSHTEFFDACEVLLS 412

Query: 328 SDKSDKENDQEHDESDNEVMGKSEESDTDT--SER-QDDSYIEPEPVEPLKETTYTEQSH 384
           +  S+ E  +E +   +E+     E   D   +ER Q    +   P+ P +       S 
Sbjct: 413 ASSSENEGSEEEESCTSEITTSLSEEMLDLRGAERCQKGGCVPGRPMGPPRRRCLPAAS- 471

Query: 385 EELGEAGEASQTETVSEENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSDYYY 444
              G   + S            +W +L+    G DLSKV +P  + EP + L +L +   
Sbjct: 472 ---GPGADVS------------LWNILRN-NIGKDLSKVSMPVQLNEPLNTLQRLCEELE 515

Query: 445 HADFLSEAALEENPYFRLKKVVKWYLSGFYKK-PKGLKKPYNPILGETFRCLWIHPRTNS 503
           ++  L +A+   +P  R+  +  + +S +     +   KP+NP+LGET+ C     R + 
Sbjct: 516 YSSLLDQASRIADPCERMVYIAAFAVSAYSSTYHRAGCKPFNPVLGETYEC----ERPDR 571

Query: 504 KTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARLTFLNRG 563
              +I+EQVSHHPPISA +  +  + F     +  K+KF+G SL  +  G   ++    G
Sbjct: 572 GFRFISEQVSHHPPISACHAES--ENFAFWQDMKWKNKFWGKSLEIVPVGTVNVSLPRFG 629

Query: 564 EDYVMTMPYAHCKGILYGTMTLELGGTVNI--TCQKTGYSAILEFKLKPFLGSSDCVNQI 621
           + +      +    +L G   +E  G V I  T   + +  I   K K +   S  V+++
Sbjct: 630 DHFEWNKVTSCIHNVLSGQRWIEHYGEVLIRNTQDSSCHCKITFCKAKYW---SSNVHEV 686

Query: 622 SGK-LKLGKEVLATLEGHWDSEVFITDKKTDNSEVFWNPT---PDIKQWRLIRHTVKFE- 676
            G  L     VL  L G W   ++     T   +  W P    PD        H   F  
Sbjct: 687 QGAVLSRSGRVLHRLFGKWHEGLY--RGPTPGGQCIWKPNSMPPD--------HERNFGF 736

Query: 677 EQGDFESEKLWQRVTRAINAKDQTEATQEKYVLEEAQRQAARDRKTKNEE 726
            Q   E  +L   + R++ + D      ++Y LEE   QAA  +K + E+
Sbjct: 737 TQFALELNELTAELKRSLPSTDTRLRPDQRY-LEEGNIQAAEAQKRRIEQ 785


>gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens]
          Length = 916

 Score = 92.8 bits (229), Expect = 1e-18
 Identities = 129/547 (23%), Positives = 218/547 (39%), Gaps = 88/547 (16%)

Query: 249 SESDGRCWMDALELALKCSSLLKRTMIREGKEHDLSVSSDSTHVTFYGLLRANNLHSGDN 308
           +E   R W  AL+   +    L+ T+ +  K+H+              L RA   HS   
Sbjct: 378 AEIHSRKWQRALQYEQEQRVHLEETIEQLAKQHN-------------SLERA--FHSAPG 422

Query: 309 FQLNDSEIERQHFKDQDMYSDKSDKENDQEHDESDNEVMGKSEESD---TDTSERQDDSY 365
              N S+     F +  + + K +   D E DE D E     E+S    T  +E ++DS 
Sbjct: 423 RPANPSK----SFIEGSLLTPKGE---DSEEDE-DTEYFDAMEDSTSFITVITEAKEDS- 473

Query: 366 IEPEPVEPLKETTYTEQSHEE----------LGEAGEASQTETVSEENKSL-IWTLLKQV 414
                 E    T+  + S  +           G +    +    ++ N SL +W+++K  
Sbjct: 474 ---RKAEGSTGTSSVDWSSADNVLDGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNC 530

Query: 415 RPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFY 474
             G +LS++ +P    EP S L +L++   +   L +A    +   ++  V  + +S + 
Sbjct: 531 I-GRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYS 589

Query: 475 KKPKGLKKPYNPILGETFRCLWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSG 534
                + KP+NP+LGETF    +    +     + EQVSHHPP +A YV + K G+ L  
Sbjct: 590 TTVHRIAKPFNPMLGETFE---LDRLDDMGLRSLCEQVSHHPPSAAHYVFS-KHGWSLWQ 645

Query: 535 SILAKSKFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNIT 594
            I   SKF G  +S +  G   L F   G  YV     +    I+ G + ++  G + I 
Sbjct: 646 EITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIV 705

Query: 595 CQKTGYSAILEFKLKPFLGSSDCVNQISGKLKLGK-EVLATLEGHWDSEVFI-------- 645
             KT     L+F    +  S +   +++G +   + +    L G WD ++          
Sbjct: 706 NHKTNDRCQLKFLPYSYF-SKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSP 764

Query: 646 ----------TDKKTDNSEVFWNPTP------DIKQWRLIRHTVKFEEQGDFESEKLWQR 689
                     T  +T ++++ W   P      ++  +  +  T+   E+G   ++   + 
Sbjct: 765 SSPSSDGKQKTVYQTLSAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLRP 824

Query: 690 VTRAINAKDQTEATQEKYVLEEAQRQAARDRK---------TKNEEWSCKLF-------E 733
             R +      EA  EK  LEE QR + R R          +  EE     +        
Sbjct: 825 DQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLEACGPGSSCSSEEEKEADAYTPLWFEKR 884

Query: 734 LDPLTGE 740
           LDPLTGE
Sbjct: 885 LDPLTGE 891


>gi|21735584 oxysterol-binding protein-like protein 3 isoform d
           [Homo sapiens]
          Length = 820

 Score = 91.3 bits (225), Expect = 4e-18
 Identities = 84/336 (25%), Positives = 148/336 (44%), Gaps = 33/336 (9%)

Query: 271 KRTMIREGKEHDLSVSSDSTHVTFYGLLRANN--------LHSGDN-FQLNDSEIERQHF 321
           +R  +++  E D S S  +  +     L + N        +H   N  +L+ ++   + F
Sbjct: 326 EREKLKQLMEQDASSSPSAQVIGLKNALSSENSRDENRALVHQLSNESRLSITDSLSEFF 385

Query: 322 KDQDMYSDKSDKENDQEHDESDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKETTYTE 381
             Q++    S  EN+   D  D+ V   S+    D      D+  E + + P+ ++    
Sbjct: 386 DAQEVLLSPSSSENEISDD--DSYVSDISDNLSLDNLSNDLDN--ERQTLGPVLDSGREA 441

Query: 382 QSHEELGEAGEASQTETVSEENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSD 441
           +S            +  +S      +W +L+    G DLSKV +P  + EP + L +L +
Sbjct: 442 KSRRRTCLPAPCPSSSNIS------LWNILRN-NIGKDLSKVAMPVELNEPLNTLQRLCE 494

Query: 442 YYYHADFLSEAALEENPYFRLKKV----VKWYLSGFYKKPKGLKKPYNPILGETFRCLWI 497
              +++ L +AA   +P  R+  V    +  Y S +Y+      KP+NP+LGET+ C+  
Sbjct: 495 ELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAG---SKPFNPVLGETYECI-- 549

Query: 498 HPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARL 557
             R +    + +EQVSHHPPISA +  +R   F     +  K+KF+G S+  +  G   +
Sbjct: 550 --REDKGFQFFSEQVSHHPPISACHAESR--NFVFWQDVRWKNKFWGKSMEIVPIGTTHV 605

Query: 558 TFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNI 593
           T    G+ +      +    IL G   +E  G + I
Sbjct: 606 TLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVI 641


>gi|21735582 oxysterol-binding protein-like protein 3 isoform c
           [Homo sapiens]
          Length = 851

 Score = 91.3 bits (225), Expect = 4e-18
 Identities = 84/336 (25%), Positives = 148/336 (44%), Gaps = 33/336 (9%)

Query: 271 KRTMIREGKEHDLSVSSDSTHVTFYGLLRANN--------LHSGDN-FQLNDSEIERQHF 321
           +R  +++  E D S S  +  +     L + N        +H   N  +L+ ++   + F
Sbjct: 357 EREKLKQLMEQDASSSPSAQVIGLKNALSSENSRDENRALVHQLSNESRLSITDSLSEFF 416

Query: 322 KDQDMYSDKSDKENDQEHDESDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKETTYTE 381
             Q++    S  EN+   D  D+ V   S+    D      D+  E + + P+ ++    
Sbjct: 417 DAQEVLLSPSSSENEISDD--DSYVSDISDNLSLDNLSNDLDN--ERQTLGPVLDSGREA 472

Query: 382 QSHEELGEAGEASQTETVSEENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSD 441
           +S            +  +S      +W +L+    G DLSKV +P  + EP + L +L +
Sbjct: 473 KSRRRTCLPAPCPSSSNIS------LWNILRN-NIGKDLSKVAMPVELNEPLNTLQRLCE 525

Query: 442 YYYHADFLSEAALEENPYFRLKKV----VKWYLSGFYKKPKGLKKPYNPILGETFRCLWI 497
              +++ L +AA   +P  R+  V    +  Y S +Y+      KP+NP+LGET+ C+  
Sbjct: 526 ELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAG---SKPFNPVLGETYECI-- 580

Query: 498 HPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARL 557
             R +    + +EQVSHHPPISA +  +R   F     +  K+KF+G S+  +  G   +
Sbjct: 581 --REDKGFQFFSEQVSHHPPISACHAESR--NFVFWQDVRWKNKFWGKSMEIVPIGTTHV 636

Query: 558 TFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNI 593
           T    G+ +      +    IL G   +E  G + I
Sbjct: 637 TLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVI 672


>gi|21735580 oxysterol-binding protein-like protein 3 isoform b
           [Homo sapiens]
          Length = 856

 Score = 90.1 bits (222), Expect = 8e-18
 Identities = 74/279 (26%), Positives = 126/279 (45%), Gaps = 24/279 (8%)

Query: 319 QHFKDQDMYSDKSDKENDQEHDESDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKETT 378
           + F  Q++    S  EN+   D  D+ V   S+    D      D+  E + + P+ ++ 
Sbjct: 419 EFFDAQEVLLSPSSSENEISDD--DSYVSDISDNLSLDNLSNDLDN--ERQTLGPVLDSG 474

Query: 379 YTEQSHEELGEAGEASQTETVSEENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDK 438
              +S            +  +S      +W +L+    G DLSKV +P  + EP + L +
Sbjct: 475 REAKSRRRTCLPAPCPSSSNIS------LWNILRN-NIGKDLSKVAMPVELNEPLNTLQR 527

Query: 439 LSDYYYHADFLSEAALEENPYFRLKKV----VKWYLSGFYKKPKGLKKPYNPILGETFRC 494
           L +   +++ L +AA   +P  R+  V    +  Y S +Y+      KP+NP+LGET+ C
Sbjct: 528 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAG---SKPFNPVLGETYEC 584

Query: 495 LWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGE 554
           +    R +    + +EQVSHHPPISA +  +R   F     +  K+KF+G S+  +  G 
Sbjct: 585 I----REDKGFQFFSEQVSHHPPISACHAESR--NFVFWQDVRWKNKFWGKSMEIVPIGT 638

Query: 555 ARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNI 593
             +T    G+ +      +    IL G   +E  G + I
Sbjct: 639 THVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVI 677


>gi|14149704 oxysterol-binding protein-like protein 3 isoform a
           [Homo sapiens]
          Length = 887

 Score = 90.1 bits (222), Expect = 8e-18
 Identities = 74/279 (26%), Positives = 126/279 (45%), Gaps = 24/279 (8%)

Query: 319 QHFKDQDMYSDKSDKENDQEHDESDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKETT 378
           + F  Q++    S  EN+   D  D+ V   S+    D      D+  E + + P+ ++ 
Sbjct: 450 EFFDAQEVLLSPSSSENEISDD--DSYVSDISDNLSLDNLSNDLDN--ERQTLGPVLDSG 505

Query: 379 YTEQSHEELGEAGEASQTETVSEENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDK 438
              +S            +  +S      +W +L+    G DLSKV +P  + EP + L +
Sbjct: 506 REAKSRRRTCLPAPCPSSSNIS------LWNILRN-NIGKDLSKVAMPVELNEPLNTLQR 558

Query: 439 LSDYYYHADFLSEAALEENPYFRLKKV----VKWYLSGFYKKPKGLKKPYNPILGETFRC 494
           L +   +++ L +AA   +P  R+  V    +  Y S +Y+      KP+NP+LGET+ C
Sbjct: 559 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAG---SKPFNPVLGETYEC 615

Query: 495 LWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGE 554
           +    R +    + +EQVSHHPPISA +  +R   F     +  K+KF+G S+  +  G 
Sbjct: 616 I----REDKGFQFFSEQVSHHPPISACHAESR--NFVFWQDVRWKNKFWGKSMEIVPIGT 669

Query: 555 ARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNI 593
             +T    G+ +      +    IL G   +E  G + I
Sbjct: 670 THVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVI 708


>gi|22749303 hypothetical protein LOC196477 [Homo sapiens]
          Length = 406

 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 33/112 (29%), Positives = 53/112 (47%), Gaps = 9/112 (8%)

Query: 293 TFYGLLRANNLHSGDNFQLNDSEIERQHFKDQDMYSDKSDKENDQEHDESDNEVMGKSEE 352
           T YG ++  +L    N + N S           +  ++ +K+ND E +E D EV    E 
Sbjct: 249 TLYGFVQNPSLAFSPNPEENQSLAPL-------LVEEEEEKKNDDE-EEYDQEVCDAKEA 300

Query: 353 SDTDTSERQDDSYIEPEPVEPLKETTYTEQSHEELGEAGEASQTETVSEENK 404
           S+ +     ++  +E E  E ++E  Y E+  EEL E  E  + E V EEN+
Sbjct: 301 SEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEEL-EEEELEEEEEVLEENE 351


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 24/76 (31%), Positives = 38/76 (50%), Gaps = 3/76 (3%)

Query: 329 DKSDKENDQEHDESDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKETTYTEQSHEELG 388
           + SD+E ++E +E + E   + EE D +  E  ++ Y E E  E   E  + E+  EE G
Sbjct: 884 NSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEE---EEEFEEEFEEEEG 940

Query: 389 EAGEASQTETVSEENK 404
           E  E  + E   EE +
Sbjct: 941 ELEEEEEEEDEEEEEE 956



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 21/82 (25%), Positives = 39/82 (47%), Gaps = 4/82 (4%)

Query: 308 NFQLNDSEIERQHFKDQDMYSDKSDKENDQEHDESDNEVMGKSEESDTDTSERQDDSYIE 367
           N   +D E E +  ++++   ++ ++E D E +E D E   + EE +    E  ++ + E
Sbjct: 882 NINSSDEEEEEEE-EEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEE---EEEFEEEFEE 937

Query: 368 PEPVEPLKETTYTEQSHEELGE 389
            E     +E    E+  EEL E
Sbjct: 938 EEGELEEEEEEEDEEEEEELEE 959


>gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]
          Length = 569

 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 34/119 (28%), Positives = 51/119 (42%), Gaps = 15/119 (12%)

Query: 299 RANNLHSGDN------FQLNDSEIERQHFKDQDMYSDKSDKENDQEHD----ESDNEVMG 348
           R + LHS D       FQ    E E +  K ++    K +KE ++E +    E + E+  
Sbjct: 353 RRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRN 412

Query: 349 KSEE--SDTDTSERQDDSYIEPE---PVEPLKETTYTEQSHEELGEAGEASQTETVSEE 402
           K+EE     D  +  +D   +PE     +P  E TY E   E L EA +    E +  E
Sbjct: 413 KNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEEPLDEAQDDDLDELMEME 471


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.130    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,720,341
Number of Sequences: 37866
Number of extensions: 1637564
Number of successful extensions: 9367
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 134
Number of HSP's successfully gapped in prelim test: 259
Number of HSP's that attempted gapping in prelim test: 7477
Number of HSP's gapped (non-prelim): 1624
length of query: 889
length of database: 18,247,518
effective HSP length: 111
effective length of query: 778
effective length of database: 14,044,392
effective search space: 10926536976
effective search space used: 10926536976
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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