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Search of human proteins with 18034775
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18034775 PHD finger protein 20 [Homo sapiens]
(1012 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18034775 PHD finger protein 20 [Homo sapiens] 2091 0.0
gi|111120331 PHD finger protein 20-like 1 isoform 1 [Homo sapiens] 546 e-155
gi|39653325 PHD finger protein 20-like 1 isoform 3 [Homo sapiens] 207 3e-53
gi|109134330 PHD finger protein 20-like 1 isoform 2 [Homo sapiens] 202 1e-51
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 61 5e-09
gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 60 8e-09
gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 60 8e-09
gi|167466270 PHD finger protein 13 [Homo sapiens] 59 2e-08
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 59 2e-08
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 59 2e-08
gi|125656165 THO complex 2 [Homo sapiens] 58 4e-08
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 57 9e-08
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 57 9e-08
gi|87299628 biorientation of chromosomes in cell division 1-like... 57 1e-07
gi|116268091 PHD finger protein 23 [Homo sapiens] 56 2e-07
gi|110349788 absent, small, or homeotic 1-like [Homo sapiens] 55 3e-07
gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens] 51 5e-06
gi|38788260 bromodomain PHD finger transcription factor isoform ... 50 1e-05
gi|38788274 bromodomain PHD finger transcription factor isoform ... 50 1e-05
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 48 4e-05
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens] 48 5e-05
gi|71044477 death inducer-obliterator 1 isoform b [Homo sapiens] 48 5e-05
gi|18375619 death inducer-obliterator 1 isoform a [Homo sapiens] 48 5e-05
gi|18375617 death inducer-obliterator 1 isoform a [Homo sapiens] 48 5e-05
gi|11225260 DNA topoisomerase I [Homo sapiens] 47 7e-05
gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens] 47 7e-05
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 46 2e-04
gi|7657218 bromodomain-containing protein 4 isoform short [Homo ... 46 2e-04
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 46 2e-04
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 45 3e-04
>gi|18034775 PHD finger protein 20 [Homo sapiens]
Length = 1012
Score = 2091 bits (5418), Expect = 0.0
Identities = 1012/1012 (100%), Positives = 1012/1012 (100%)
Query: 1 MTKHPPNRRGISFEVGAQLEARDRLKNWYPAHIEDIDYEEGKVLIHFKRWNHRYDEWFCW 60
MTKHPPNRRGISFEVGAQLEARDRLKNWYPAHIEDIDYEEGKVLIHFKRWNHRYDEWFCW
Sbjct: 1 MTKHPPNRRGISFEVGAQLEARDRLKNWYPAHIEDIDYEEGKVLIHFKRWNHRYDEWFCW 60
Query: 61 DSPYLRPLEKIQLRKEGLHEEDGSSEFQINEQVLACWSDCRFYPAKVTAVNKDGTYTVKF 120
DSPYLRPLEKIQLRKEGLHEEDGSSEFQINEQVLACWSDCRFYPAKVTAVNKDGTYTVKF
Sbjct: 61 DSPYLRPLEKIQLRKEGLHEEDGSSEFQINEQVLACWSDCRFYPAKVTAVNKDGTYTVKF 120
Query: 121 YDGVVQTVKHIHVKAFSKDQNIVGNARPKETDHKSLSSSPDKREKFKEQRKATVNVKKDK 180
YDGVVQTVKHIHVKAFSKDQNIVGNARPKETDHKSLSSSPDKREKFKEQRKATVNVKKDK
Sbjct: 121 YDGVVQTVKHIHVKAFSKDQNIVGNARPKETDHKSLSSSPDKREKFKEQRKATVNVKKDK 180
Query: 181 EDKPLKTEKRPKQPDKEGKLICSEKGKVSEKSLPKNEKEDKENISENDREYSGDAQVDKK 240
EDKPLKTEKRPKQPDKEGKLICSEKGKVSEKSLPKNEKEDKENISENDREYSGDAQVDKK
Sbjct: 181 EDKPLKTEKRPKQPDKEGKLICSEKGKVSEKSLPKNEKEDKENISENDREYSGDAQVDKK 240
Query: 241 PENDIVKSPQENLREPKRKRGRPPSIAPTAVDSNSQTLQPITLELRRRKISKGCEVPLKR 300
PENDIVKSPQENLREPKRKRGRPPSIAPTAVDSNSQTLQPITLELRRRKISKGCEVPLKR
Sbjct: 241 PENDIVKSPQENLREPKRKRGRPPSIAPTAVDSNSQTLQPITLELRRRKISKGCEVPLKR 300
Query: 301 PRLDKNSSQEKSKNYSENTDKDLSRRRSSRLSTNGTHEILDPDLVVSDLVDTDPLQDTLS 360
PRLDKNSSQEKSKNYSENTDKDLSRRRSSRLSTNGTHEILDPDLVVSDLVDTDPLQDTLS
Sbjct: 301 PRLDKNSSQEKSKNYSENTDKDLSRRRSSRLSTNGTHEILDPDLVVSDLVDTDPLQDTLS 360
Query: 361 STKESEEGQLKSALEAGQVSSALTCHSFGDGSGAAGLELNCPSMGENTMKTEPTSPLVEL 420
STKESEEGQLKSALEAGQVSSALTCHSFGDGSGAAGLELNCPSMGENTMKTEPTSPLVEL
Sbjct: 361 STKESEEGQLKSALEAGQVSSALTCHSFGDGSGAAGLELNCPSMGENTMKTEPTSPLVEL 420
Query: 421 QEISTVEVTNTFKKTDDFGSSNAPAVDLDHKFRCKVVDCLKFFRKAKLLHYHMKYFHGME 480
QEISTVEVTNTFKKTDDFGSSNAPAVDLDHKFRCKVVDCLKFFRKAKLLHYHMKYFHGME
Sbjct: 421 QEISTVEVTNTFKKTDDFGSSNAPAVDLDHKFRCKVVDCLKFFRKAKLLHYHMKYFHGME 480
Query: 481 KSLEPEESPGKRHVQTRGPSASDKPSQETLTRKRVSASSPTTKDKEKNKEKKFKEFVRVK 540
KSLEPEESPGKRHVQTRGPSASDKPSQETLTRKRVSASSPTTKDKEKNKEKKFKEFVRVK
Sbjct: 481 KSLEPEESPGKRHVQTRGPSASDKPSQETLTRKRVSASSPTTKDKEKNKEKKFKEFVRVK 540
Query: 541 PKKKKKKKKKTKPECPCSEEISDTSQEPSPPKAFAVTRCGSSHKPGVHMSPQLHGPESGH 600
PKKKKKKKKKTKPECPCSEEISDTSQEPSPPKAFAVTRCGSSHKPGVHMSPQLHGPESGH
Sbjct: 541 PKKKKKKKKKTKPECPCSEEISDTSQEPSPPKAFAVTRCGSSHKPGVHMSPQLHGPESGH 600
Query: 601 HKGKVKALEEDNLSESSSESFLWSDDEYGQDVDVTTNPDEELDGDDRYDFEVVRCICEVQ 660
HKGKVKALEEDNLSESSSESFLWSDDEYGQDVDVTTNPDEELDGDDRYDFEVVRCICEVQ
Sbjct: 601 HKGKVKALEEDNLSESSSESFLWSDDEYGQDVDVTTNPDEELDGDDRYDFEVVRCICEVQ 660
Query: 661 EENDFMIQCEECQCWQHGVCMGLLEENVPEKYTCYVCQDPPGQRPGFKYWYDKEWLSRGH 720
EENDFMIQCEECQCWQHGVCMGLLEENVPEKYTCYVCQDPPGQRPGFKYWYDKEWLSRGH
Sbjct: 661 EENDFMIQCEECQCWQHGVCMGLLEENVPEKYTCYVCQDPPGQRPGFKYWYDKEWLSRGH 720
Query: 721 MHGLAFLEENYSHQNAKKIVATHQLLGDVQRVIEVLHGLQLKMSILQSREHPDLPLWCQP 780
MHGLAFLEENYSHQNAKKIVATHQLLGDVQRVIEVLHGLQLKMSILQSREHPDLPLWCQP
Sbjct: 721 MHGLAFLEENYSHQNAKKIVATHQLLGDVQRVIEVLHGLQLKMSILQSREHPDLPLWCQP 780
Query: 781 WKQHSGEGRSHFRNIPVTDTRSKEEAPSYRTLNGAVEKPRPLALPLPRSVEESYITSEHC 840
WKQHSGEGRSHFRNIPVTDTRSKEEAPSYRTLNGAVEKPRPLALPLPRSVEESYITSEHC
Sbjct: 781 WKQHSGEGRSHFRNIPVTDTRSKEEAPSYRTLNGAVEKPRPLALPLPRSVEESYITSEHC 840
Query: 841 YQKPRAYYPAVEQKLVVETRGSALDDAVNPLHENGDDSLSPRLGWPLDQDRSKGDSDPKP 900
YQKPRAYYPAVEQKLVVETRGSALDDAVNPLHENGDDSLSPRLGWPLDQDRSKGDSDPKP
Sbjct: 841 YQKPRAYYPAVEQKLVVETRGSALDDAVNPLHENGDDSLSPRLGWPLDQDRSKGDSDPKP 900
Query: 901 GSPKVKEYVSKKALPEEAPARKLLDRGGEGLLSSQHQWQFNLLTHVESLQDEVTHRMDSI 960
GSPKVKEYVSKKALPEEAPARKLLDRGGEGLLSSQHQWQFNLLTHVESLQDEVTHRMDSI
Sbjct: 901 GSPKVKEYVSKKALPEEAPARKLLDRGGEGLLSSQHQWQFNLLTHVESLQDEVTHRMDSI 960
Query: 961 EKELDVLESWLDYTGELEPPEPLARLPQLKHCIKQLLMDLGKVQQIALCCST 1012
EKELDVLESWLDYTGELEPPEPLARLPQLKHCIKQLLMDLGKVQQIALCCST
Sbjct: 961 EKELDVLESWLDYTGELEPPEPLARLPQLKHCIKQLLMDLGKVQQIALCCST 1012
>gi|111120331 PHD finger protein 20-like 1 isoform 1 [Homo sapiens]
Length = 1017
Score = 546 bits (1407), Expect = e-155
Identities = 401/1129 (35%), Positives = 557/1129 (49%), Gaps = 231/1129 (20%)
Query: 1 MTKHPPNRRGISFEVGAQLEARDRLKNWYPAHIEDIDYEEGKVLIHFKRWNHRYDEWFCW 60
M+K PPNR GI+FE+GA+LEA D L+ WYP+ IE IDYEEGK+L+HF+RW+HRYDEW W
Sbjct: 1 MSKKPPNRPGITFEIGARLEALDYLQKWYPSRIEKIDYEEGKMLVHFERWSHRYDEWIYW 60
Query: 61 DSPYLRPLEKIQLRKEGLHEEDGSSEFQINEQVLACWSDCRFYPAKVTAVNKDGTYTVKF 120
DS LRPLE+ LRKEGL +E+ +F+ E+VLA W+DCR+YPAK+ A+NK+GT+TV+F
Sbjct: 61 DSNRLRPLERPALRKEGLKDEEDFFDFKAGEEVLARWTDCRYYPAKIEAINKEGTFTVQF 120
Query: 121 YDGVVQTVKHIHVKAFSKD------------------------------------QNIVG 144
YDGV++ +K +H+KA +D +
Sbjct: 121 YDGVIRCLKRMHIKAMPEDAKGQVKSQHPLSWCCPIDPAGSCNQSMGSEDWIALVKAAAA 180
Query: 145 NARPKETDHKSLSSSPDKREKFKEQRK---------------ATVNVKKDKEDKP----- 184
A +T K +S+ ++K K++RK AT +V+K KED P
Sbjct: 181 AAAKNKTGSKPRTSANSNKDKDKDERKWFKVPSKKEETSTCIATPDVEK-KEDLPTSSET 239
Query: 185 --LKTEKRPKQ--PDKEGKLICSEK------------------GKVSEKSLPKNEKEDKE 222
L E PK P E L K G ++ K++ + E KE
Sbjct: 240 FGLHVENVPKMVFPQPESTLSNKRKNNQGNSFQAKRARLNKITGLLASKAVGVDGAEKKE 299
Query: 223 NISEN----DREYSGDAQVDKKPENDI---------------VKSPQENLREPKRKRG-- 261
+ +E ++ S Q KK E DI + S + ++ K + G
Sbjct: 300 DYNETAPMLEQAISPKPQSQKKNEADISSSANTQKPALLSSTLSSGKARSKKCKHESGDS 359
Query: 262 ----RPPS--IAPTAVDSNSQTLQPITLELRRRKISK-GCEVPLKRPRLDKNSSQEKSKN 314
+PP ++P + TL +L I+K P+ PR K+S +
Sbjct: 360 SGCIKPPKSPLSPELIQVEDLTL---VSQLSSSVINKTSPPQPVNPPRPFKHSER----- 411
Query: 315 YSENTDKDLSRRRSSRLSTNGTHEILDPDLVVSDLVDTDPLQDTLSSTKESEEGQLKSAL 374
RRRS RL+T + PD V + P D + S+ Q S
Sbjct: 412 ----------RRRSQRLAT-----LPMPDDSVEKVSSPSPATDGKVFSISSQNQQESSVP 456
Query: 375 EAGQVSSALTCHSFGDG---SGAAGLELNCPSMGENTMKTEPTSPLVELQEISTVEVTNT 431
E V+ L G + G E+ P +++ + E P E ++ + ++
Sbjct: 457 EVPDVAH-LPLEKLGPCLPLDLSRGSEVTAPVASDSSYRNE--CPRAEKEDTQMLPNPSS 513
Query: 432 FKKTDDFGSSNAPAVDLDHKFRCKVVD-CLKFFRKAKLLHYHMKYFHGMEKSLEPEESPG 490
D G+ A + K + K+ D F K K EK E E
Sbjct: 514 KAIADGRGAPAAAGISKTEK-KVKLEDKSSTAFGKRK------------EKDKERREKRD 560
Query: 491 KRHVQTRGPSASDKPSQETLTRKRVSASSPTTKDKEKNKEKKFKEFVRVKPKKKKKKKKK 550
K H +P Q+ K K+K K+ K ++ + + ++
Sbjct: 561 KDHY---------RPKQK--------------KKKKKKKKSKQHDYSDYEDSSLEFLER- 596
Query: 551 TKPECPCSEEISDTSQEPSPPKAFAVTRCGSSHKPGVHMSPQLHGPESGHHKGKVKALEE 610
CS ++ +S ++ + + P +S L G +
Sbjct: 597 ------CSSPLTRSSGSSLASRSMFTEKTTTYQYPRAILSVDLSGENLS---------DV 641
Query: 611 DNLSESSSESFLWSDDEYGQDVDVTTNPDEELDGDDRYDFEVVRCICEVQEENDFMIQCE 670
D L +SS+ES L S DEY QD D +TN +E D DD + E+VRCICE+ EEN FMIQCE
Sbjct: 642 DFLDDSSTESLLLSGDEYNQDFD-STNFEESQDEDDALN-EIVRCICEMDEENGFMIQCE 699
Query: 671 ECQCWQHGVCMGLLEENVPEKYTCYVCQDPPGQRPGFKYWYDKEWLSRGHMHGLAFLEEN 730
EC CWQH VCMGLLEE++PE+Y CY+C+DPPGQR KY YDKEWL+ G M GL+F +EN
Sbjct: 700 ECLCWQHSVCMGLLEESIPEQYICYICRDPPGQRWSAKYRYDKEWLNNGRMCGLSFFKEN 759
Query: 731 YSHQNAKKIVATHQLLGDVQRVIEVLHGLQLKMSILQSREHPDLPLW-CQPWKQHSGEGR 789
YSH NAKKIV+TH LL DV V EVLHGLQLK+ IL+++ HPDL LW C ++ +
Sbjct: 760 YSHLNAKKIVSTHHLLADVYGVTEVLHGLQLKIGILKNKHHPDLHLWACSGKRKDQDQII 819
Query: 790 SHFRNIPVTDTRSKEEAPSYRTLNGAVEKPRPLALPLPRSVEESYITSEHCYQKPRAYYP 849
+ DT ++EE + + E PR LP +E +YITSEH YQKP+++
Sbjct: 820 AGVEKKIAQDTVNREEK---KYVQNHKEPPR-----LPLKMEGTYITSEHSYQKPQSFGQ 871
Query: 850 AVEQKLVVETRGSALDDAVNPLHENGDDSLSPRLGWPLDQDRSKGDSDPKPGSPKVKEYV 909
+ + GS+ DD V+ L E + + RSK +Y
Sbjct: 872 DCKS---LADPGSSDDDDVSSLEEEQEFHM-----------RSKNS----------LQYS 907
Query: 910 SKK-ALPEEAPARKLL------DRGGEGLLSSQHQWQFNLLTHVESLQDEVTHRMDSIEK 962
+K+ +PE+ PA +G E S QWQ NLLTH+E++Q+EVT RMD IEK
Sbjct: 908 AKEHGMPEKNPAEGNTVFVYNDKKGTEDPGDSHLQWQLNLLTHIENVQNEVTSRMDLIEK 967
Query: 963 ELDVLESWLDYTGELEPPEPLARLPQLKHCIKQLLMDLGKVQQIALCCS 1011
E+DVLESWLD+TGELEPP+PLARLPQLK IKQLL+D+GKVQQIA CS
Sbjct: 968 EVDVLESWLDFTGELEPPDPLARLPQLKRHIKQLLIDMGKVQQIATLCS 1016
>gi|39653325 PHD finger protein 20-like 1 isoform 3 [Homo sapiens]
Length = 285
Score = 207 bits (528), Expect = 3e-53
Identities = 107/241 (44%), Positives = 153/241 (63%), Gaps = 14/241 (5%)
Query: 1 MTKHPPNRRGISFEVGAQLEARDRLKNWYPAHIEDIDYEEGKVLIHFKRWNHRYDEWFCW 60
M+K PPNR GI+FE+GA+LEA D L+ WYP+ IE IDYEEGK+L+HF+RW+HRYDEW W
Sbjct: 1 MSKKPPNRPGITFEIGARLEALDYLQKWYPSRIEKIDYEEGKMLVHFERWSHRYDEWIYW 60
Query: 61 DSPYLRPLEKIQLRKEGLHEEDGSSEFQINEQVLACWSDCRFYPAKVTAVNKDGTYTVKF 120
DS LRPLE+ LRKEGL +E+ +F+ E+VLA W+DCR+YPAK+ A+NK+GT+TV+F
Sbjct: 61 DSNRLRPLERPALRKEGLKDEEDFFDFKAGEEVLARWTDCRYYPAKIEAINKEGTFTVQF 120
Query: 121 YDGVVQTVKHIHVKAFSKD----------QNIVGNARPKETDHKSLSSSPDKREKFKEQR 170
YDGV++ +K +H+KA +D + A +T K +S+ ++K K++R
Sbjct: 121 YDGVIRCLKRMHIKAMPEDAKGQDWIALVKAAAAAAAKNKTGSKPRTSANSNKDKDKDER 180
Query: 171 K-ATVNVKKDKEDKPLKTEKRPKQPDKEGKLICSEKGKVSEKSLPKNEKEDKENISENDR 229
K V KK++ + T P KE SE + +++PK E+ N R
Sbjct: 181 KWFKVPSKKEETSTCIAT---PDVEKKEDLPTSSETFGLHVENVPKMVFPQPESTLSNKR 237
Query: 230 E 230
+
Sbjct: 238 K 238
Score = 31.6 bits (70), Expect = 3.9
Identities = 27/120 (22%), Positives = 59/120 (49%), Gaps = 17/120 (14%)
Query: 458 DCLKFFRKAKLLH----YHMKYFHGMEKSLE-------PEESPGKRHVQTRGPSASDKPS 506
DC + K + ++ + ++++ G+ + L+ PE++ G+ + +A+
Sbjct: 99 DCRYYPAKIEAINKEGTFTVQFYDGVIRCLKRMHIKAMPEDAKGQDWIALVKAAAAAAAK 158
Query: 507 QETLTRKRVSASSPTTKDKEKNKEKKFKEFVRVKPKKKKKKKKKTKPECPCSEEISDTSQ 566
+T ++ R SA+S KDK+K++ K FK V KK++ P+ E++ +S+
Sbjct: 159 NKTGSKPRTSANS--NKDKDKDERKWFK----VPSKKEETSTCIATPDVEKKEDLPTSSE 212
>gi|109134330 PHD finger protein 20-like 1 isoform 2 [Homo sapiens]
Length = 573
Score = 202 bits (514), Expect = 1e-51
Identities = 135/402 (33%), Positives = 195/402 (48%), Gaps = 50/402 (12%)
Query: 1 MTKHPPNRRGISFEVGAQLEARDRLKNWYPAHIEDIDYEEGKVLIHFKRWNHRYDEWFCW 60
M+K PPNR GI+FE+GA+LEA D L+ WYP+ IE IDYEEGK+L+HF+RW+HRYDEW W
Sbjct: 1 MSKKPPNRPGITFEIGARLEALDYLQKWYPSRIEKIDYEEGKMLVHFERWSHRYDEWIYW 60
Query: 61 DSPYLRPLEKIQLRKEGLHEEDGSSEFQINEQVLACWSDCRFYPAKVTAVNKDGTYTVKF 120
DS LRPLE+ LRKEGL +E+ +F+ E+VLA W+DCR+YPAK+ A+NK+GT+TV+F
Sbjct: 61 DSNRLRPLERPALRKEGLKDEEDFFDFKAGEEVLARWTDCRYYPAKIEAINKEGTFTVQF 120
Query: 121 YDGVVQTVKHIHVKAFSKD-QNIVGNARPKE-----TDHKSLSSSPDKREKFKEQRKATV 174
YDGV++ +K +H+KA +D + V + P S + S + + A
Sbjct: 121 YDGVIRCLKRMHIKAMPEDAKGQVKSQHPLSWCCPIDPAGSCNQSMGSEDWIALVKAAAA 180
Query: 175 NVKKDKE-DKPLKTEKRPKQPDKEGKLICSEKGKVSEKS--LPKNEKEDKENISENDREY 231
K+K KP + K DK+ + K E S + + E KE++ + +
Sbjct: 181 AAAKNKTGSKPRTSANSNKDKDKDERKWFKVPSKKEETSTCIATPDVEKKEDLPTSSETF 240
Query: 232 SGDAQVDKKPENDIVKSPQENLREPKRKRGRPPSIAPTAVDSNSQTLQPITLELRRRKIS 291
EN+ P + P QP + +RK +
Sbjct: 241 GLHV---------------ENV---------PKMVFP----------QPESTLSNKRKNN 266
Query: 292 KGCEVPLKRPRLDKNSSQEKSKNYSENTDKDLSRRRSSRLSTNGTHEILDPDLVVSDLVD 351
+G KR RL+K + SK + + N T +L+ +
Sbjct: 267 QGNSFQAKRARLNKITGLLASKAVGVD-------GAEKKEDYNETAPMLEQAISPKPQSQ 319
Query: 352 TDPLQDTLSSTKESEEGQLKSALEAGQVSSALTCHSFGDGSG 393
D SS + L S L +G+ S H GD SG
Sbjct: 320 KKNEADISSSANTQKPALLSSTLSSGKARSKKCKHESGDSSG 361
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 61.2 bits (147), Expect = 5e-09
Identities = 105/470 (22%), Positives = 175/470 (37%), Gaps = 52/470 (11%)
Query: 147 RPKETDHKSLSSSPDKREKFKEQRKATVNVKK-DKEDKPLKTEKRP----KQPDK----- 196
+ K + S P+ + KE+ K+ VK +K P K E + K P+K
Sbjct: 549 KAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPV 608
Query: 197 --EGKLICSEKGKVSEKSLPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSPQENLR 254
E K K V E++ E + E +E + + K PE + KSP E +
Sbjct: 609 KEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSP-EKAK 667
Query: 255 EPKRKRGRPPSIAPTAVDSNSQTLQPITLELRRRKISKGCEVPLKRPRLDKNSSQEKSKN 314
P + + P A + V + +++ + ++ S K P ++ S EK+K+
Sbjct: 668 SPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPE---KAKSPVKEEAKSPEKAKS 724
Query: 315 YSENTDKDLSRRRSS-RLSTNGTHEILDPD----LVVSDLVDTDPLQDTLSSTKESEEGQ 369
+ K + +S + + P+ L V P ++ S + +
Sbjct: 725 PVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEK 784
Query: 370 LKSALEAGQVSSALTCHSFGDGSGAAGLELNCPSMGENTMKTEPTSPLVELQEISTVEVT 429
KS ++ S + + A E+ K E SP+ E ++ V+V
Sbjct: 785 AKSPVKEEVKSPEKAKSPLKEDAKAPEKEI--------PKKEEVKSPVKEEEKPQEVKVK 836
Query: 430 NTFKKTDDFGSSNAPAVD-LDHKFRCKVVDCLKFFRKAKLLHYHMKYFHGMEKSLEP--- 485
KK ++ APA + K K + K ++A K +EK E
Sbjct: 837 EPPKKAEE---EKAPATPKTEEKKDSKKEEAPK--KEAPKPKVEEKKEPAVEKPKESKVE 891
Query: 486 ---EESPGKRHVQTRGPSA--------SDKPSQETLTRKRVSASSPTTKDKEKNKEKK-- 532
EE+ K+ V T A KP ++T K+ K+ K EKK
Sbjct: 892 AKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKK-EPDDAKAKEPSKPAEKKEA 950
Query: 533 FKEFVRVKPKKKKKKKKKTKPECPCSEEISDTSQEPSPPKAFAVTRCGSS 582
E K +K KK ++K K E E+ S+EPS PKA + S+
Sbjct: 951 APEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSST 1000
Score = 56.6 bits (135), Expect = 1e-07
Identities = 94/469 (20%), Positives = 175/469 (37%), Gaps = 66/469 (14%)
Query: 159 SPDKREKFKEQRKATVNVKKDKEDKPLKTEKRPKQPDKEGKLICSEKGKVSEKSLPKNEK 218
S +K + ++ K TV V++ E+ + TE+ ++ +KE K E+
Sbjct: 440 SEEKIKVVEKSEKETVIVEEQTEETQV-TEEVTEEEEKEAK-----------------EE 481
Query: 219 EDKENISENDREYSGDAQVDKKPENDIVKSPQENLREPKRKRGRPPSIA----------P 268
E KE + E G + K P + SP++ + P ++ + P+ A P
Sbjct: 482 EGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSP 541
Query: 269 TAVDSNSQTLQPITLELRRRKISKGCE-------VPLKRPRLDKNSSQEKSKNYSENTDK 321
V S + P E + +K E +K P K+ ++E++K+ +E
Sbjct: 542 AEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSP 601
Query: 322 DLSR-------RRSSRLSTNGTHEILDPDLVVSDLVDTDPLQDTLSSTKESEEGQLKSAL 374
+ ++ + + + E P V S P ++ S ++++ + + A
Sbjct: 602 EKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAK 661
Query: 375 EAGQVSSALTCHSFGDGSGAAGL--ELNCPSMGENTMKTEPTSPLVELQEISTVEVTNTF 432
+ S + + + + E P ++ +K E SP + +
Sbjct: 662 SPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEK 721
Query: 433 KKTDDFGSSNAP-AVDLDHKFRCKVVDCLKFFRKAKLLHYHM---------KYFHGMEKS 482
K+ + P K K + K KAK L + +K
Sbjct: 722 AKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKF 781
Query: 483 LEPEESPGKRHVQT----RGPSASDKPSQETLTRKRVSASSPTTKDKEKNKEKKFKEFVR 538
E +SP K V++ + P D + E K+ SP K++EK +E K KE
Sbjct: 782 PEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSP-VKEEEKPQEVKVKE--- 837
Query: 539 VKPKKKKKKKKKTKPECPCSEEISDTSQEPSPPKAFAVTRCGSSHKPGV 587
PKK +++K P P +EE D+ +E +P K + +P V
Sbjct: 838 -PPKKAEEEK---APATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAV 882
Score = 55.1 bits (131), Expect = 3e-07
Identities = 87/437 (19%), Positives = 157/437 (35%), Gaps = 44/437 (10%)
Query: 147 RPKETDHKSLSSSPDKREKFKEQRKATVNVKK-DKEDKPLKTE----KRPKQPDKEGKLI 201
+ K + S + + KE+ K+ VK +K P K E ++ K P+KE
Sbjct: 603 KAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKE---- 658
Query: 202 CSEKGKVSEKSLPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSPQENLREPKRKRG 261
K KS K E + E + + + K P + KSP E + P ++
Sbjct: 659 -EAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSP-EKAKSPVKEEA 716
Query: 262 RPPSIAPTAVDSNSQTLQPITLELRRR-KISKGCEVPLKRPRLDKNSSQEKSKNYSENTD 320
+ P A + V ++T + ++ K + + P K LD S + K+ E
Sbjct: 717 KSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEA-- 774
Query: 321 KDLSRRRSSRLSTNGTHEILDPDLVVSDLVDTDPLQDTLSSTKESEEGQLKSALEAGQVS 380
+ + + + + E+ P+ S L + + KE + +K + +V
Sbjct: 775 RSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVK 834
Query: 381 SALTCHSFGDGSGAAG--LELNCPSMGENTMKTEPTSPLVELQEISTVEVTNTFK----K 434
+ A E S E K E P VE ++ VE K K
Sbjct: 835 VKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKK 894
Query: 435 TDDFGSSNAPAVDLDHKFRCKVVDCLKFFRKAKLLHYHMKYFHGMEKSLEPEESPGKRHV 494
+ P + + + +V + K K ++ EP+++ K
Sbjct: 895 EEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVA------------KKEPDDAKAK--- 939
Query: 495 QTRGPSASDKPSQETLTRKRVSASSPTTKDKEKNKEKKFKEFVRVKPKKKKKKKKKTKPE 554
+PS+ ++ T ++K K E+K K + K K K+ +KP+
Sbjct: 940 ---------EPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPK 990
Query: 555 CPCSEEISDTSQEPSPP 571
+E+ S T Q+ S P
Sbjct: 991 AEKAEKSSSTDQKDSKP 1007
Score = 50.8 bits (120), Expect = 6e-06
Identities = 48/192 (25%), Positives = 83/192 (43%), Gaps = 16/192 (8%)
Query: 133 VKAFSKDQNIVGNARPKETDHKSLSSSPDKREKFKEQRKATVNVKKDKEDKPLKTEKRPK 192
VK K Q + PK+ + + ++P EK K+ +K E+ P K +PK
Sbjct: 824 VKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEK-KDSKK---------EEAPKKEAPKPK 873
Query: 193 QPDKEGKLICSEKGKVSEKSLPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSPQEN 252
+K+ + EK K S+ K E EDK+ + ++E A+V+ K + + +
Sbjct: 874 VEEKKEPAV--EKPKESKVEAKKEEAEDKKKVPTPEKE--APAKVEVKEDAKPKEKTEVA 929
Query: 253 LREPKRKRGRPPSIAPTAVDSNSQTLQPITLELRRRKISKGCEVPLKRPRLDKNSSQEKS 312
+EP + + PS A + + T E + +K + + K DK S+E S
Sbjct: 930 KKEPDDAKAKEPS--KPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPS 987
Query: 313 KNYSENTDKDLS 324
K +E +K S
Sbjct: 988 KPKAEKAEKSSS 999
Score = 50.4 bits (119), Expect = 8e-06
Identities = 89/429 (20%), Positives = 169/429 (39%), Gaps = 60/429 (13%)
Query: 158 SSPDKREKFKEQRKATVNVKK-DKEDKPLKTEKRP----KQPDKEGKLICSEKGKVSEKS 212
S + + KE+ K+ VK +K P K E + K P+KE E +E
Sbjct: 526 SPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKE------EAKSPAEVK 579
Query: 213 LPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSPQENLREPKRKRGRPPSIAPTAVD 272
P+ K + +++ E + K P + KSP E + P ++ + +P V
Sbjct: 580 SPEKAKSPAKEEAKSPAEAKSPEKA-KSPVKEEAKSPAE-AKSPVKEEAK----SPAEVK 633
Query: 273 SNSQTLQPITLELRRRKISKGCEVPLKRPRLDKNSSQEKSKNYSENTDKDLSRRRSSRLS 332
S + P E + + +K P ++ S EK+K+ + K + +S +
Sbjct: 634 SPEKAKSPTKEEAKSPEKAKS-------PEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKA 686
Query: 333 TNGTHEILDPDLVVSDLVDTDPLQDTLSSTKESEEGQLKSALEAGQVSSALTCHSFGDGS 392
E P+ S P+++ S ++++ + A + S +
Sbjct: 687 -----EAKSPEKAKS------PVKEEAKSPEKAKSPVKEEAKSPEKAKSPVK-------- 727
Query: 393 GAAGLELNCPSMGENTMKTEPTSP--LVELQEISTVEVTNTFKKTDDFGSSNAPAVDLDH 450
E P ++ +K E SP ++ T++V + KT + +PA
Sbjct: 728 ----EEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPE 783
Query: 451 KFRCKVVDCLKFFRKAKL-LHYHMKYFHGMEKSLEPEESPGKRHVQTRGPSASDKPSQET 509
K + V + +K KAK L K E +SP K + + + P +
Sbjct: 784 KAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKK-- 841
Query: 510 LTRKRVSASSPTTKDKEKNKEKKFKEFVRVKPKKKKKKK------KKTKPECPCSEEISD 563
+ + ++P T++K+ +K+++ + KPK ++KK+ K++K E EE D
Sbjct: 842 -AEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAK-KEEAED 899
Query: 564 TSQEPSPPK 572
+ P+P K
Sbjct: 900 KKKVPTPEK 908
Score = 41.6 bits (96), Expect = 0.004
Identities = 41/188 (21%), Positives = 78/188 (41%), Gaps = 7/188 (3%)
Query: 134 KAFSKDQNIVGNARPKETDHKSLSSSPDKREKFKEQRKATVNVKKDKEDKPLKTEKRPKQ 193
KA S + V + ++ K + +P+K KE+ K+ VK++++ + +K ++ PK+
Sbjct: 784 KAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSP--VKEEEKPQEVKVKEPPKK 841
Query: 194 PDKEGKLICSEKGKVSEKSLPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSPQENL 253
++E K EK K E+ K+ + E + V+K E+ + +E
Sbjct: 842 AEEEK---APATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEE-- 896
Query: 254 REPKRKRGRPPSIAPTAVDSNSQTLQPITLELRRRKISKGCEVPLKRPRLDKNSSQEKSK 313
E K+K P AP V+ E+ +++ +P K ++ EK
Sbjct: 897 AEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKD 956
Query: 314 NYSENTDK 321
E K
Sbjct: 957 TKEEKAKK 964
Score = 37.0 bits (84), Expect = 0.094
Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 2/85 (2%)
Query: 138 KDQNIVGNARPKETDHKSLSSSPDKREKFKEQRKATVNVKKDKEDKPLKTEKRPKQPDKE 197
K++ V P + K S +K+E E++ K E+KP KTE + K+ DK
Sbjct: 923 KEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKP-KTEAKAKEDDKT 981
Query: 198 -GKLICSEKGKVSEKSLPKNEKEDK 221
K K + +EKS ++K+ K
Sbjct: 982 LSKEPSKPKAEKAEKSSSTDQKDSK 1006
>gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
sapiens]
Length = 1858
Score = 60.5 bits (145), Expect = 8e-09
Identities = 27/83 (32%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Query: 616 SSSESFLWSDDEYGQDVDVTTNPDEELDGDDRYDFEVVRCICEVQEENDFMIQCEECQCW 675
S +E +++ + + TT E D Y +V RCIC ++ +MI C++C W
Sbjct: 85 SKNEVGIFTTPNFDETSSATTISTSE---DGSYGTDVTRCICGFTHDDGYMICCDKCSVW 141
Query: 676 QHGVCMGLLEENVPEKYTCYVCQ 698
QH CMG+ +++P+ Y C CQ
Sbjct: 142 QHIDCMGIDRQHIPDTYLCERCQ 164
>gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
sapiens]
Length = 1858
Score = 60.5 bits (145), Expect = 8e-09
Identities = 27/83 (32%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Query: 616 SSSESFLWSDDEYGQDVDVTTNPDEELDGDDRYDFEVVRCICEVQEENDFMIQCEECQCW 675
S +E +++ + + TT E D Y +V RCIC ++ +MI C++C W
Sbjct: 85 SKNEVGIFTTPNFDETSSATTISTSE---DGSYGTDVTRCICGFTHDDGYMICCDKCSVW 141
Query: 676 QHGVCMGLLEENVPEKYTCYVCQ 698
QH CMG+ +++P+ Y C CQ
Sbjct: 142 QHIDCMGIDRQHIPDTYLCERCQ 164
>gi|167466270 PHD finger protein 13 [Homo sapiens]
Length = 300
Score = 59.3 bits (142), Expect = 2e-08
Identities = 50/196 (25%), Positives = 74/196 (37%), Gaps = 18/196 (9%)
Query: 504 KPSQETLTRKRVSASSPTTKDKEKNKEKKFKEFVRVKPKKKKKKKKKTKPECPCSEEISD 563
KPS L RK+ K K ++ + KE R K + E P S + D
Sbjct: 102 KPSNFLLDRKKTDKLKKKKKRKRRDSDAPGKEGYRGGLLKLEAADPYV--ETPTSPTLQD 159
Query: 564 TSQEPSPPKAFAVTRCGSSHKPGVHMSPQLHGPESGHHKGKVKALEEDNLSESSSESFLW 623
Q PS P + + SS Q+ ++K + + +
Sbjct: 160 IPQAPSDPCSGWDSDTPSSGSCATVSPDQVK---------EIKTEGKRTIVRQGKQVVFR 210
Query: 624 SDDEYGQDVDVTTNPDEELDGDDRYDFEVVRCICEVQEENDFMIQCEECQCWQHGVCMGL 683
+D G D D+ + D DD +D +V C C MI+C EC W H C +
Sbjct: 211 DEDSTGNDEDIMVDSD-----DDSWD--LVTCFCMKPFAGRPMIECNECHTWIHLSCAKI 263
Query: 684 LEENVPEKYTCYVCQD 699
+ NVPE + C C+D
Sbjct: 264 RKSNVPEVFVCQKCRD 279
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 58.9 bits (141), Expect = 2e-08
Identities = 117/570 (20%), Positives = 218/570 (38%), Gaps = 100/570 (17%)
Query: 129 KHIHVKAFSKDQNIVGNARPK-----------ETDHKSLSSSPDKREKFKEQRKATVNVK 177
KH+ K K Q+ + + K E D K ++++K + +K + ++
Sbjct: 909 KHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKME 968
Query: 178 KDKEDKPLKTEKRPKQPD--------KEGKLICSEKGKVSEKSLPKNEKEDKENISENDR 229
+ E TEK P++ + K+ K ++ K S+K K K+ K+ +S+
Sbjct: 969 QQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKK-KDELSDYAE 1027
Query: 230 EYSG-----DAQVDKKPENDIVKSPQEN---LREPKRKRG-------RPPSIAPTAVDSN 274
+ +G D+ DKK +N ++ L + RKR S+ +S+
Sbjct: 1028 KSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSS 1087
Query: 275 SQTLQPITLELRRRKISKGC--EVPLKRPRLDKNSSQEKSKNYSENTD---KDLSRRRSS 329
+ L+ I L RR SK E+ D S E +K + T K + +
Sbjct: 1088 DKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKK 1147
Query: 330 RLSTNGTHEILDPDLVVSDLVDTDPLQDTLSSTKESEEGQLKSALEAGQVSSALTCHS-F 388
R S + + D+ S D + S+E ++K E + L+ H+ F
Sbjct: 1148 RNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTE----NLVLSSHTGF 1203
Query: 389 GDGSGAAGLELNCP-SMGENTMKTEPTSPLVELQEISTVEVTNTFKKTDDFGSSNAPAVD 447
SG L + P ++ ++ +P + + + + E+ +D S + P
Sbjct: 1204 CQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLE--EIKANLSSDEDGSSDDEPE-- 1259
Query: 448 LDHKFRCKVVDCLKFFRKAKLLHYHMKYFHGMEKS-LEPEESPGKRHVQTRGPSASDKPS 506
G +++ + EE+PG + + S SD S
Sbjct: 1260 -----------------------------EGKKRTGKQNEENPGDEEAKNQVNSESDSDS 1290
Query: 507 QETLT---RKRVSASSPTTKDKEKNKEKKF--KEFVRVKPKKKKKKKKKTK-----PECP 556
+E+ R R+ T D E +EKK KE VK + ++K + E
Sbjct: 1291 EESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESG 1350
Query: 557 CSEEISDTSQEPSPPKAFAVTRCGSSHKPGVHMSPQLHGPESGHHKGKVKALEEDNLSES 616
SEE+S++ E P R S+ K + + + + + + KV +ED+ SE+
Sbjct: 1351 VSEEVSESEDEQRP-------RTRSAKKAELEENQRSYKQKKKRRRIKV---QEDSSSEN 1400
Query: 617 SSESFLWSDDEYGQDVDVTTNPDEELDGDD 646
S S +++ ++ + +EE D +D
Sbjct: 1401 KSNSEEEEEEKEEEEEEEEEEEEEEEDEND 1430
Score = 40.4 bits (93), Expect = 0.008
Identities = 29/127 (22%), Positives = 60/127 (47%), Gaps = 7/127 (5%)
Query: 132 HVKAFSKDQNIVGNARPKETDHKSLSSSPDKREKFKEQRKATVNVKKDKEDKPLKTEKRP 191
H + +++ V + +++D + S + E EQR T + KK + ++ ++
Sbjct: 1325 HKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEE---NQRSY 1381
Query: 192 KQPDKEGKLICSEKGKVSEKSLPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSPQE 251
KQ K ++ E KS + E+E+KE E + E + +++ END KSP +
Sbjct: 1382 KQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEE----EEEEEEDENDDSKSPGK 1437
Query: 252 NLREPKR 258
++ ++
Sbjct: 1438 GRKKIRK 1444
Score = 37.0 bits (84), Expect = 0.094
Identities = 91/448 (20%), Positives = 173/448 (38%), Gaps = 74/448 (16%)
Query: 147 RPKETDHKSLSSSPDKREKFKEQRKATVNV-KKDKEDKPLKTEKRPKQPDKEGKLICSEK 205
RP ET+ + +S + E KE++K +V V KKDK + PK P+K K
Sbjct: 628 RPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPK-PNK------LPK 680
Query: 206 GKVSEKSLPKNEKEDK-----ENISENDREYSGDAQVDKKPEN--DIVKSPQENLREPKR 258
K SE ++ +N D+ + +S S D +++ N + + ++ K
Sbjct: 681 SKQSE-TVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKG 739
Query: 259 KRGRPPSIAPTAVDSNSQTLQPITLELRRRKISKGCEVPLKRPRLDKNSSQEKSKNYSEN 318
KR R S + + D+ ++ K +K + K K +Q +S NY
Sbjct: 740 KRKRKSSTSGSDFDT------------KKGKSAKSSIISKK-----KRQTQSESSNYDSE 782
Query: 319 TDKDLSRRRSSRLSTNGTHEILDPDLVVSDLVDTDPLQDTLSSTKESEEGQLKSALEAGQ 378
+K++ + S++ T + P + D D +D S K+ + Q L+ Q
Sbjct: 783 LEKEI--KSMSKIGAARTTKKRIP-----NTKDFDSSEDEKHS-KKGMDNQGHKNLKTSQ 834
Query: 379 VSSALTC------HSFGDGSGAAGLELNCPSMGENTMKTEPTSPLVE-LQEISTVEVTNT 431
S+ +F G + + + K + S + + ++S E + T
Sbjct: 835 EGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFT 894
Query: 432 FKKTDDFGSSNAPAVDLDHKFRCKVVDCL-----KFFRKAKLLHYHMKYFHGMEKSLEPE 486
+ + + L K KV D L KF +K + +++ E +
Sbjct: 895 SLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQ-----------SDETSEDD 943
Query: 487 ESPGKRHVQTRGPSASDKPSQETLTRKRVSASSPTTKDKEKNK-------EKKFKEFVRV 539
+ K+ + + + K + ++ S+S T K E+ + K+ K
Sbjct: 944 KKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTD 1003
Query: 540 KPKKKKKKKKKTKPECPCSEEISDTSQE 567
KK KK + KT + +E+SD +++
Sbjct: 1004 GEKKSKKIRDKTSKK---KDELSDYAEK 1028
Score = 33.9 bits (76), Expect = 0.80
Identities = 28/148 (18%), Positives = 69/148 (46%), Gaps = 24/148 (16%)
Query: 149 KETDHKSLSSSPDKREKFKEQRKATVNVKKDKEDKPLKTEKRPKQPDKEGKLICSEKGKV 208
+++ ++ S+S ++ E+ +E+ + ++++ED+ ++ K K K++ +K +
Sbjct: 1394 EDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRT 1453
Query: 209 SEKSLPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSPQENLREPKRKRGRPPSIAP 268
++ K E+E ++ I+E +RE +E LRE P+ P
Sbjct: 1454 ETQNALKEEEERRKRIAERERE-------------------REKLREVIEIEDASPTKCP 1494
Query: 269 ----TAVDSNSQTLQPITLELRRRKISK 292
+D + +T +P+ +++ R + K
Sbjct: 1495 ITTKLVLDEDEETKEPL-VQVHRNMVIK 1521
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 58.9 bits (141), Expect = 2e-08
Identities = 117/570 (20%), Positives = 218/570 (38%), Gaps = 100/570 (17%)
Query: 129 KHIHVKAFSKDQNIVGNARPK-----------ETDHKSLSSSPDKREKFKEQRKATVNVK 177
KH+ K K Q+ + + K E D K ++++K + +K + ++
Sbjct: 947 KHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKME 1006
Query: 178 KDKEDKPLKTEKRPKQPD--------KEGKLICSEKGKVSEKSLPKNEKEDKENISENDR 229
+ E TEK P++ + K+ K ++ K S+K K K+ K+ +S+
Sbjct: 1007 QQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKK-KDELSDYAE 1065
Query: 230 EYSG-----DAQVDKKPENDIVKSPQEN---LREPKRKRG-------RPPSIAPTAVDSN 274
+ +G D+ DKK +N ++ L + RKR S+ +S+
Sbjct: 1066 KSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSS 1125
Query: 275 SQTLQPITLELRRRKISKGC--EVPLKRPRLDKNSSQEKSKNYSENTD---KDLSRRRSS 329
+ L+ I L RR SK E+ D S E +K + T K + +
Sbjct: 1126 DKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKK 1185
Query: 330 RLSTNGTHEILDPDLVVSDLVDTDPLQDTLSSTKESEEGQLKSALEAGQVSSALTCHS-F 388
R S + + D+ S D + S+E ++K E + L+ H+ F
Sbjct: 1186 RNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTE----NLVLSSHTGF 1241
Query: 389 GDGSGAAGLELNCP-SMGENTMKTEPTSPLVELQEISTVEVTNTFKKTDDFGSSNAPAVD 447
SG L + P ++ ++ +P + + + + E+ +D S + P
Sbjct: 1242 CQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLE--EIKANLSSDEDGSSDDEPE-- 1297
Query: 448 LDHKFRCKVVDCLKFFRKAKLLHYHMKYFHGMEKS-LEPEESPGKRHVQTRGPSASDKPS 506
G +++ + EE+PG + + S SD S
Sbjct: 1298 -----------------------------EGKKRTGKQNEENPGDEEAKNQVNSESDSDS 1328
Query: 507 QETLT---RKRVSASSPTTKDKEKNKEKKF--KEFVRVKPKKKKKKKKKTK-----PECP 556
+E+ R R+ T D E +EKK KE VK + ++K + E
Sbjct: 1329 EESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESG 1388
Query: 557 CSEEISDTSQEPSPPKAFAVTRCGSSHKPGVHMSPQLHGPESGHHKGKVKALEEDNLSES 616
SEE+S++ E P R S+ K + + + + + + KV +ED+ SE+
Sbjct: 1389 VSEEVSESEDEQRP-------RTRSAKKAELEENQRSYKQKKKRRRIKV---QEDSSSEN 1438
Query: 617 SSESFLWSDDEYGQDVDVTTNPDEELDGDD 646
S S +++ ++ + +EE D +D
Sbjct: 1439 KSNSEEEEEEKEEEEEEEEEEEEEEEDEND 1468
Score = 40.4 bits (93), Expect = 0.008
Identities = 29/127 (22%), Positives = 60/127 (47%), Gaps = 7/127 (5%)
Query: 132 HVKAFSKDQNIVGNARPKETDHKSLSSSPDKREKFKEQRKATVNVKKDKEDKPLKTEKRP 191
H + +++ V + +++D + S + E EQR T + KK + ++ ++
Sbjct: 1363 HKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEE---NQRSY 1419
Query: 192 KQPDKEGKLICSEKGKVSEKSLPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSPQE 251
KQ K ++ E KS + E+E+KE E + E + +++ END KSP +
Sbjct: 1420 KQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEE----EEEEEEDENDDSKSPGK 1475
Query: 252 NLREPKR 258
++ ++
Sbjct: 1476 GRKKIRK 1482
Score = 37.0 bits (84), Expect = 0.094
Identities = 91/448 (20%), Positives = 173/448 (38%), Gaps = 74/448 (16%)
Query: 147 RPKETDHKSLSSSPDKREKFKEQRKATVNV-KKDKEDKPLKTEKRPKQPDKEGKLICSEK 205
RP ET+ + +S + E KE++K +V V KKDK + PK P+K K
Sbjct: 666 RPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPK-PNK------LPK 718
Query: 206 GKVSEKSLPKNEKEDK-----ENISENDREYSGDAQVDKKPEN--DIVKSPQENLREPKR 258
K SE ++ +N D+ + +S S D +++ N + + ++ K
Sbjct: 719 SKQSE-TVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKG 777
Query: 259 KRGRPPSIAPTAVDSNSQTLQPITLELRRRKISKGCEVPLKRPRLDKNSSQEKSKNYSEN 318
KR R S + + D+ ++ K +K + K K +Q +S NY
Sbjct: 778 KRKRKSSTSGSDFDT------------KKGKSAKSSIISKK-----KRQTQSESSNYDSE 820
Query: 319 TDKDLSRRRSSRLSTNGTHEILDPDLVVSDLVDTDPLQDTLSSTKESEEGQLKSALEAGQ 378
+K++ + S++ T + P + D D +D S K+ + Q L+ Q
Sbjct: 821 LEKEI--KSMSKIGAARTTKKRIP-----NTKDFDSSEDEKHS-KKGMDNQGHKNLKTSQ 872
Query: 379 VSSALTC------HSFGDGSGAAGLELNCPSMGENTMKTEPTSPLVE-LQEISTVEVTNT 431
S+ +F G + + + K + S + + ++S E + T
Sbjct: 873 EGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFT 932
Query: 432 FKKTDDFGSSNAPAVDLDHKFRCKVVDCL-----KFFRKAKLLHYHMKYFHGMEKSLEPE 486
+ + + L K KV D L KF +K + +++ E +
Sbjct: 933 SLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQ-----------SDETSEDD 981
Query: 487 ESPGKRHVQTRGPSASDKPSQETLTRKRVSASSPTTKDKEKNK-------EKKFKEFVRV 539
+ K+ + + + K + ++ S+S T K E+ + K+ K
Sbjct: 982 KKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTD 1041
Query: 540 KPKKKKKKKKKTKPECPCSEEISDTSQE 567
KK KK + KT + +E+SD +++
Sbjct: 1042 GEKKSKKIRDKTSKK---KDELSDYAEK 1066
Score = 33.9 bits (76), Expect = 0.80
Identities = 28/148 (18%), Positives = 69/148 (46%), Gaps = 24/148 (16%)
Query: 149 KETDHKSLSSSPDKREKFKEQRKATVNVKKDKEDKPLKTEKRPKQPDKEGKLICSEKGKV 208
+++ ++ S+S ++ E+ +E+ + ++++ED+ ++ K K K++ +K +
Sbjct: 1432 EDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRT 1491
Query: 209 SEKSLPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSPQENLREPKRKRGRPPSIAP 268
++ K E+E ++ I+E +RE +E LRE P+ P
Sbjct: 1492 ETQNALKEEEERRKRIAERERE-------------------REKLREVIEIEDASPTKCP 1532
Query: 269 ----TAVDSNSQTLQPITLELRRRKISK 292
+D + +T +P+ +++ R + K
Sbjct: 1533 ITTKLVLDEDEETKEPL-VQVHRNMVIK 1559
>gi|125656165 THO complex 2 [Homo sapiens]
Length = 1593
Score = 58.2 bits (139), Expect = 4e-08
Identities = 70/306 (22%), Positives = 130/306 (42%), Gaps = 46/306 (15%)
Query: 107 VTAVNKDGTYTVKFYDGVVQTVKHIHVKAFSKDQNIVGNARPKETDHKSLSSSPDKREKF 166
V AVNK + T K + + + KA ++ G + KE K+ +++P+ R
Sbjct: 1238 VKAVNKASSTTPKGNSSNGNSGSNSN-KAVKENDKEKGKEKEKEKKEKTPATTPEARVLG 1296
Query: 167 KEQRKATVNVKKDKEDKPLKTEKRPKQPDKEGKLICSEKGKVSEKSLPKNEKEDKENISE 226
K+ ++ + +K++K +T++R + DKE + E+ EK + ++ E
Sbjct: 1297 KDGKEKPKEERPNKDEKARETKERTPKSDKEKEKFKKEEKAKDEKFKTTVPNAESKSTQE 1356
Query: 227 NDREYSGDAQVD---------------KKPENDIVKS--PQENLREPKRKRGRPPSIAPT 269
+RE + D K P + +KS P+ ++ EP+R++ R I
Sbjct: 1357 REREKEPSRERDIAKEMKSKENVKGGEKTPVSGSLKSPVPRSDIPEPEREQKR-RKIDTH 1415
Query: 270 AVDSNSQTLQPITLELRRRK-----------ISKGCEVPLKRPRLDKNSSQEKSKNYSEN 318
S+S T++ +EL+ +SK E + + LDK S+E+S+ +
Sbjct: 1416 PSPSHSSTVKDSLIELKESSAKLYINHTPPPLSKSKEREMDKKDLDK--SRERSREREKK 1473
Query: 319 TDKDLSRRRSSRLSTNGTHEILDPDLV-----------VSDLVDTDPLQDTLSSTKESEE 367
+KD R+ R +N E+ PDL VS P + + K+ E+
Sbjct: 1474 DEKD--RKERKRDHSNNDREV-PPDLTKRRKEENGTMGVSKHKSESPCESPYPNEKDKEK 1530
Query: 368 GQLKSA 373
+ KS+
Sbjct: 1531 NKSKSS 1536
Score = 33.9 bits (76), Expect = 0.80
Identities = 29/106 (27%), Positives = 46/106 (43%), Gaps = 14/106 (13%)
Query: 147 RPKETDHKSLSSSPDKREKFKEQRKATVNVKKDKEDKPLKTEKRPKQPDKE---GKLICS 203
R ++ + PD ++ KE+ T+ V K K + P ++ P + DKE K
Sbjct: 1481 RKRDHSNNDREVPPDLTKRRKEEN-GTMGVSKHKSESPCESPY-PNEKDKEKNKSKSSGK 1538
Query: 204 EKGKVSEKSLP---------KNEKEDKENISENDREYSGDAQVDKK 240
EKG S KS K + DKE I + ++ S + +KK
Sbjct: 1539 EKGSDSFKSEKMDKISSGGKKESRHDKEKIEKKEKRDSSGGKEEKK 1584
Score = 33.5 bits (75), Expect = 1.0
Identities = 37/148 (25%), Positives = 57/148 (38%), Gaps = 14/148 (9%)
Query: 484 EPEESPGKRHVQTR-GPSASDKPSQETLTRKRVSAS-------SPTTKDKEKNKEKKFKE 535
EPE +R + T PS S + K SA P +K KE+ +KK +
Sbjct: 1402 EPEREQKRRKIDTHPSPSHSSTVKDSLIELKESSAKLYINHTPPPLSKSKEREMDKKDLD 1461
Query: 536 FVRVKPKKKKKKKKKTKPECPCSEEISDTSQEPSPPKAFAVTRCGSSHKPGV--HMSPQL 593
R + ++++KK +K + E +D P K R + GV H S
Sbjct: 1462 KSRERSREREKKDEKDRKERKRDHSNNDREVPPDLTK----RRKEENGTMGVSKHKSESP 1517
Query: 594 HGPESGHHKGKVKALEEDNLSESSSESF 621
+ K K K + + E S+SF
Sbjct: 1518 CESPYPNEKDKEKNKSKSSGKEKGSDSF 1545
Score = 30.4 bits (67), Expect = 8.8
Identities = 28/120 (23%), Positives = 47/120 (39%), Gaps = 13/120 (10%)
Query: 478 GMEKSLEPEESPGKRHVQTR--GPSASDKPSQETLTRKRVSASSPTTKDKEKNKEKKFKE 535
G EK E +E + R G +KP +E + + + K +++KFK
Sbjct: 1274 GKEKEKEKKEKTPATTPEARVLGKDGKEKPKEERPNKDEKARETKERTPKSDKEKEKFK- 1332
Query: 536 FVRVKPKKKKKKKKKTKPECPCSEEIS----DTSQEPSPPKAFAVTRCGSSHKPGVHMSP 591
K++K K +K K P +E S + +EPS + A + G +P
Sbjct: 1333 ------KEEKAKDEKFKTTVPNAESKSTQEREREKEPSRERDIAKEMKSKENVKGGEKTP 1386
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 57.0 bits (136), Expect = 9e-08
Identities = 55/231 (23%), Positives = 97/231 (41%), Gaps = 22/231 (9%)
Query: 147 RPKETDHKSLSSSPDKREKFKEQRKATVNVKKDKEDKPLKTEKRPKQPDK-EGKLICSEK 205
R + S D REK KE+ + +KD+E + + ++R K+ ++ + K E+
Sbjct: 365 RKSRSRSHSRDKRKDTREKIKEKERVK---EKDREKEREREKEREKEKERGKNKDRDKER 421
Query: 206 GKVSEKSLPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSPQENLREPKRKRGRPPS 265
K EK K+ + ++E E DR+ + + DK+ E + +S + + + K K+ R P
Sbjct: 422 EKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPP 481
Query: 266 IAPTAVDSNSQTLQPITLELRRRKISKGCEVPLKRPRLDKNSSQEKSKNYSENTDK---- 321
+ A S+ + + E RRR+ P + + SS+ S DK
Sbjct: 482 RSYNA----SRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREK 537
Query: 322 ---DLSRRRSSRLSTNGTHEILDPDLVVSDLVDTDPLQDTLSSTKESEEGQ 369
+S RR ST+ D D + L+ +S KE E +
Sbjct: 538 ERDHISERRERERSTSMRKSSNDRD-------GKEKLEKNSTSLKEKEHNK 581
Score = 55.1 bits (131), Expect = 3e-07
Identities = 57/211 (27%), Positives = 95/211 (45%), Gaps = 29/211 (13%)
Query: 130 HIHVKAFSKDQNIVGNARPKETDHKSLSSSPDKREKFKEQRKATVNVKKDKEDKPLKTEK 189
H K + I R KE D + +REK KE+ K KD++ + K +
Sbjct: 372 HSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGK-----NKDRDKEREKDRE 426
Query: 190 RPKQPDKEGKLICSEKGKVSEKSLPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSP 249
+ K+ D+E E+ K EK ++++++KE E +RE ++D+K + D
Sbjct: 427 KDKEKDRE-----REREKEHEKD--RDKEKEKEQDKEKEREKDRSKEIDEKRKKD----- 474
Query: 250 QENLREPKR-----KRGRPPSIAPTAVDSNSQTLQPITLELRRRKISKGCEVPLKRPRLD 304
+ R P R +R R S S S + P T + +RK S+ P R R
Sbjct: 475 -KKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS---PSPRSRNK 530
Query: 305 KNSSQEKSKNY-SENTDKDLSRRRSSRLSTN 334
K+ +EK +++ SE +++ R S R S+N
Sbjct: 531 KDKKREKERDHISERRERE--RSTSMRKSSN 559
Score = 41.2 bits (95), Expect = 0.005
Identities = 57/284 (20%), Positives = 103/284 (36%), Gaps = 15/284 (5%)
Query: 144 GNARPKETDHKSLSSSPDKREKFKEQRKATVNVKKDKEDKPLKTEKRPKQPDKEGKLICS 203
G T KS SSS + + Q K + K +R K P K+ +
Sbjct: 305 GGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQ-KDRRRSKSPHKK-RSKSR 362
Query: 204 EKGKVSEKSLPKNEKED-------KENISENDREYSGDAQVDKKPENDIVKS-----PQE 251
E+ K +S +++++D KE + E DRE + + +++ E + K+ +E
Sbjct: 363 ERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKERE 422
Query: 252 NLREPKRKRGRPPSIAPTAVDSNSQTLQPITLELRRRKISKGCEVPLKRPRLDKNSSQEK 311
RE +++ R + + + + R+ + E+ KR + K+ + +
Sbjct: 423 KDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPR 482
Query: 312 SKNYSENTDKDLSRRRSSRLSTNGTHEILDPDLVVSDLVDTDPLQDTLSSTKESEEGQLK 371
S N S + RR R ++ + P K +E
Sbjct: 483 SYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHI 542
Query: 372 SALEAGQVSSALTCHSFGDGSGAAGLELNCPSMGENTMKTEPTS 415
S + S+++ S D G LE N S+ E EP S
Sbjct: 543 SERRERERSTSMR-KSSNDRDGKEKLEKNSTSLKEKEHNKEPDS 585
Score = 40.4 bits (93), Expect = 0.008
Identities = 38/143 (26%), Positives = 61/143 (42%), Gaps = 7/143 (4%)
Query: 480 EKSLEPEESPGKRHVQTRGPSASDKPSQETLTRKRVSASSPTTKDKEKNKEK---KFKEF 536
EK E E+ GK + + + +E + +DKEK KE+ K +E
Sbjct: 402 EKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREK 461
Query: 537 VRVKP---KKKKKKKKKTKPEC-PCSEEISDTSQEPSPPKAFAVTRCGSSHKPGVHMSPQ 592
R K K+KK KK +T P S +S+E ++ + +R + K S +
Sbjct: 462 DRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSR 521
Query: 593 LHGPESGHHKGKVKALEEDNLSE 615
P S + K K + E D++SE
Sbjct: 522 SPSPRSRNKKDKKREKERDHISE 544
Score = 36.6 bits (83), Expect = 0.12
Identities = 25/89 (28%), Positives = 41/89 (46%), Gaps = 2/89 (2%)
Query: 464 RKAKLLHYHMKYFHGMEKSLEPEESPGKRHVQTRGPSASDKPSQETLTRKRVSASSPTTK 523
R + H K +S S ++ + R S K S+ RK S S ++
Sbjct: 317 RSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRK--SRSRSHSR 374
Query: 524 DKEKNKEKKFKEFVRVKPKKKKKKKKKTK 552
DK K+ +K KE RVK K ++K++++ K
Sbjct: 375 DKRKDTREKIKEKERVKEKDREKEREREK 403
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 57.0 bits (136), Expect = 9e-08
Identities = 55/231 (23%), Positives = 97/231 (41%), Gaps = 22/231 (9%)
Query: 147 RPKETDHKSLSSSPDKREKFKEQRKATVNVKKDKEDKPLKTEKRPKQPDK-EGKLICSEK 205
R + S D REK KE+ + +KD+E + + ++R K+ ++ + K E+
Sbjct: 249 RKSRSRSHSRDKRKDTREKIKEKERVK---EKDREKEREREKEREKEKERGKNKDRDKER 305
Query: 206 GKVSEKSLPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSPQENLREPKRKRGRPPS 265
K EK K+ + ++E E DR+ + + DK+ E + +S + + + K K+ R P
Sbjct: 306 EKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPP 365
Query: 266 IAPTAVDSNSQTLQPITLELRRRKISKGCEVPLKRPRLDKNSSQEKSKNYSENTDK---- 321
+ A S+ + + E RRR+ P + + SS+ S DK
Sbjct: 366 RSYNA----SRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREK 421
Query: 322 ---DLSRRRSSRLSTNGTHEILDPDLVVSDLVDTDPLQDTLSSTKESEEGQ 369
+S RR ST+ D D + L+ +S KE E +
Sbjct: 422 ERDHISERRERERSTSMRKSSNDRD-------GKEKLEKNSTSLKEKEHNK 465
Score = 55.1 bits (131), Expect = 3e-07
Identities = 57/211 (27%), Positives = 95/211 (45%), Gaps = 29/211 (13%)
Query: 130 HIHVKAFSKDQNIVGNARPKETDHKSLSSSPDKREKFKEQRKATVNVKKDKEDKPLKTEK 189
H K + I R KE D + +REK KE+ K KD++ + K +
Sbjct: 256 HSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGK-----NKDRDKEREKDRE 310
Query: 190 RPKQPDKEGKLICSEKGKVSEKSLPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSP 249
+ K+ D+E E+ K EK ++++++KE E +RE ++D+K + D
Sbjct: 311 KDKEKDRE-----REREKEHEKD--RDKEKEKEQDKEKEREKDRSKEIDEKRKKD----- 358
Query: 250 QENLREPKR-----KRGRPPSIAPTAVDSNSQTLQPITLELRRRKISKGCEVPLKRPRLD 304
+ R P R +R R S S S + P T + +RK S+ P R R
Sbjct: 359 -KKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS---PSPRSRNK 414
Query: 305 KNSSQEKSKNY-SENTDKDLSRRRSSRLSTN 334
K+ +EK +++ SE +++ R S R S+N
Sbjct: 415 KDKKREKERDHISERRERE--RSTSMRKSSN 443
Score = 41.2 bits (95), Expect = 0.005
Identities = 57/284 (20%), Positives = 103/284 (36%), Gaps = 15/284 (5%)
Query: 144 GNARPKETDHKSLSSSPDKREKFKEQRKATVNVKKDKEDKPLKTEKRPKQPDKEGKLICS 203
G T KS SSS + + Q K + K +R K P K+ +
Sbjct: 189 GGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQ-KDRRRSKSPHKK-RSKSR 246
Query: 204 EKGKVSEKSLPKNEKED-------KENISENDREYSGDAQVDKKPENDIVKS-----PQE 251
E+ K +S +++++D KE + E DRE + + +++ E + K+ +E
Sbjct: 247 ERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKERE 306
Query: 252 NLREPKRKRGRPPSIAPTAVDSNSQTLQPITLELRRRKISKGCEVPLKRPRLDKNSSQEK 311
RE +++ R + + + + R+ + E+ KR + K+ + +
Sbjct: 307 KDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPR 366
Query: 312 SKNYSENTDKDLSRRRSSRLSTNGTHEILDPDLVVSDLVDTDPLQDTLSSTKESEEGQLK 371
S N S + RR R ++ + P K +E
Sbjct: 367 SYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHI 426
Query: 372 SALEAGQVSSALTCHSFGDGSGAAGLELNCPSMGENTMKTEPTS 415
S + S+++ S D G LE N S+ E EP S
Sbjct: 427 SERRERERSTSMR-KSSNDRDGKEKLEKNSTSLKEKEHNKEPDS 469
Score = 40.4 bits (93), Expect = 0.008
Identities = 38/143 (26%), Positives = 61/143 (42%), Gaps = 7/143 (4%)
Query: 480 EKSLEPEESPGKRHVQTRGPSASDKPSQETLTRKRVSASSPTTKDKEKNKEK---KFKEF 536
EK E E+ GK + + + +E + +DKEK KE+ K +E
Sbjct: 286 EKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREK 345
Query: 537 VRVKP---KKKKKKKKKTKPEC-PCSEEISDTSQEPSPPKAFAVTRCGSSHKPGVHMSPQ 592
R K K+KK KK +T P S +S+E ++ + +R + K S +
Sbjct: 346 DRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSR 405
Query: 593 LHGPESGHHKGKVKALEEDNLSE 615
P S + K K + E D++SE
Sbjct: 406 SPSPRSRNKKDKKREKERDHISE 428
Score = 36.6 bits (83), Expect = 0.12
Identities = 25/89 (28%), Positives = 41/89 (46%), Gaps = 2/89 (2%)
Query: 464 RKAKLLHYHMKYFHGMEKSLEPEESPGKRHVQTRGPSASDKPSQETLTRKRVSASSPTTK 523
R + H K +S S ++ + R S K S+ RK S S ++
Sbjct: 201 RSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRK--SRSRSHSR 258
Query: 524 DKEKNKEKKFKEFVRVKPKKKKKKKKKTK 552
DK K+ +K KE RVK K ++K++++ K
Sbjct: 259 DKRKDTREKIKEKERVKEKDREKEREREK 287
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 56.6 bits (135), Expect = 1e-07
Identities = 119/558 (21%), Positives = 210/558 (37%), Gaps = 122/558 (21%)
Query: 127 TVKHIHVKAFSKD-QNIVGNARPKETDH-KSLSSSPDKREKFKEQRKATV----NVKKDK 180
T +H ++ +KD Q + K TD + S +K E+ KE+++ T + KK +
Sbjct: 294 TKEHNNLILLNKDVQQESSEQKNKSTDKGEKKPDSNEKGERKKEKKEKTEKKFDHSKKSE 353
Query: 181 EDKPLKTEKRPKQPDKEGKLICSEKGKVSEKSLPKNEKEDKENISENDREYSGDAQV--- 237
+ + +K EK+ K+ + E + SEK K++ + KE+ S D + G +
Sbjct: 354 DTQKVKDEKQAKEKEVESLKLPSEKNSNKAKTV----EGTKEDFSLIDSDVDGLTDITVS 409
Query: 238 ---------------------DKKPENDIVKSPQENLREPKRK-------RGRPPSIAPT 269
D E +I +E ++ K K G+ S+
Sbjct: 410 SVHTSDLSSFEEDTEEEVVTSDSMEEGEITSDDEEKNKQNKTKTQTSDSSEGKTKSVRHA 469
Query: 270 AVDS-------NSQTLQPITLELRRRKISKGCEVPLKRPRLDKNSSQEKSKNYSENTDKD 322
V S + +T+E RR+ I+K E L R ++++ +EK K +E T
Sbjct: 470 YVHKPYLYSKYYSDSDDELTVEQRRQSIAKEKEERLLRRQINREKLEEKRKQKAEKT--- 526
Query: 323 LSRRRSSRLSTNGTHEILDPDLVVSDLVDTDPLQDTLSSTKESEEGQLKSALEAGQVSSA 382
+SS+ G + L+++ + + E + ++K L+ +V
Sbjct: 527 ----KSSKTKGQGRSSV--------------DLEESSTKSLEPKAARIKEVLKERKVLEK 568
Query: 383 LTCHSFGDGSGAAGLELNC---PSMGENTMKTEPTSPLVELQEISTVEVTNTFKKTDDFG 439
S + +E N E++ +T TS E ++IS+ + K
Sbjct: 569 KVALSKKRKKDSRNVEENSKKKQQYEEDSKETLKTSEHCEKEKISS---SKELKHVHAKS 625
Query: 440 SSNAPAVDLDHKFRCKVVDCLKFFRKAKLLHYHMKYFHGMEKSLEPEESPGKRHVQTRGP 499
+ PA L VVD K E LE E KR T P
Sbjct: 626 EPSKPARRLSESLH--VVDENK-----------------NESKLEREH---KRRTST--P 661
Query: 500 SASDKPSQETLTR---KRVSASSPTTKDKEKNKEKKFKEFVRVKPKKKKKKKKKTKPECP 556
+ +ET TR ++V S T++ +K K K +K KK E P
Sbjct: 662 VIMEGVQEETDTRDVKRQVERSEICTEEPQKQK----------STLKNEKHLKKDDSETP 711
Query: 557 -----CSEEISDTSQEPSPPKAFAVTRCGSSHKPGVHMSPQLH--GPESGHHKGKVKALE 609
+E+ + ++P K + + HK + +H G E+ H +
Sbjct: 712 HLKSLLKKEVKSSKEKPEREKTPSEDKLSVKHK---YKGDCMHKTGDETELHSSEKGLKV 768
Query: 610 EDNLSESSSESFLWSDDE 627
E+N+ + S ++ L SDD+
Sbjct: 769 EENIQKQSQQTKLSSDDK 786
Score = 47.0 bits (110), Expect = 9e-05
Identities = 60/235 (25%), Positives = 101/235 (42%), Gaps = 18/235 (7%)
Query: 150 ETDH-KSLSSSPDKREKFKEQRKATVNVKKDKEDKPLKTEKRPKQPDKEGKLICSEKGKV 208
ET H KSL K K K +R+ T + K K + K D E +L SEKG
Sbjct: 709 ETPHLKSLLKKEVKSSKEKPEREKTPSEDKLSVKHKYKGDCMHKTGD-ETELHSSEKGLK 767
Query: 209 SEKSLPK---------NEKEDKENISENDREYSGDAQVDKKPENDIVKSPQENLREPKRK 259
E+++ K ++K ++++ N+R+ S + D KP ++ + EN+R+ K
Sbjct: 768 VEENIQKQSQQTKLSSDDKTERKSKHRNERKLSVLGK-DGKPVSEYIIKTDENVRKENNK 826
Query: 260 RGRPPSIAPTAVDSNSQTLQPITLELRRRKISKGC-EVPLKRPRLDKNSSQEKSKNYSEN 318
+ R S T + S+ + + + +K S G + + R ++ S++K S N
Sbjct: 827 KERRLSAEKTKAEHKSRR----SSDSKIQKDSLGSKQHGITLQRRSESYSEDKCDMDSTN 882
Query: 319 TDKDLSRRRSSRLSTNGTHEILDPDLVVSDLVDTDPLQDTLSSTKESEEGQLKSA 373
D +L T +L+ LV+ T Q + T E +EG K A
Sbjct: 883 MDSNLKPEEVVHKEKRRTKSLLEEKLVLKSKSKTQGKQVKVVET-ELQEGATKQA 936
Score = 41.2 bits (95), Expect = 0.005
Identities = 99/465 (21%), Positives = 165/465 (35%), Gaps = 86/465 (18%)
Query: 106 KVTAVNKDGTYTVKFYDGVVQTVKHIHVKAFSKDQNIVGNARPKETDHKSLSSSPDKREK 165
K++ + KDG ++ +++T +++ + K++ + +A + +HKS SS K +K
Sbjct: 798 KLSVLGKDGKPVSEY---IIKTDENVRKENNKKERRL--SAEKTKAEHKSRRSSDSKIQK 852
Query: 166 ------------------FKEQRKATVNVKKDKEDKP---LKTEKRPKQPDKEGKLICSE 204
+ E + + D KP + EKR + E KL+
Sbjct: 853 DSLGSKQHGITLQRRSESYSEDKCDMDSTNMDSNLKPEEVVHKEKRRTKSLLEEKLVLKS 912
Query: 205 KGKVSEKSLPKNEKE--------------DKE-NISENDREYSGDAQVDKKPENDIVKSP 249
K K K + E E DKE N END E ++V+ KP + P
Sbjct: 913 KSKTQGKQVKVVETELQEGATKQATTPKPDKEKNTEENDSEKQRKSKVEDKPFEETGVEP 972
Query: 250 ----QENLREPKRKRGRPPSIAPTAVDSNSQTLQPITLELRRRKISKGCEVPLKRPRLDK 305
+ +K + P A + + L RK+S G + R K
Sbjct: 973 VLETASSSAHSTQKDSSHRAKLPLAKEKYKSDKDSTSTRL-ERKLSDG-----HKSRSLK 1026
Query: 306 NSSQE-KSKNYSENTDKDLSRRRSSRLSTNGTHEILDPDLVVSDLVDTDPLQDTLSSTKE 364
+SS++ K K+ +++ DKD SS G +++ L E
Sbjct: 1027 HSSKDIKKKDENKSDDKDGKEVDSSHEKARGNSSLMEKKL--------------SRRLCE 1072
Query: 365 SEEGQLKSALEAGQVSSALTCHSFGDGSGAAGLELNCPSMGENTMKTEPTSPLVELQEIS 424
+ G L + G+ A S GS L P M P +E+
Sbjct: 1073 NRRGSLSQEMAKGEEKLAANTLSTPSGS-----SLQRPKK-SGDMTLIPEQEPMEIDSEP 1126
Query: 425 TVEVTNTFKKTDDFGSSNAPAVDLDHKFRCKVVDCLKFFRKAKLLHYHMKYFHGMEKSLE 484
VE KT D ++N+ D+D + +K A + ++ K+
Sbjct: 1127 GVENVFEVSKTQDNRNNNSQQ-DIDS-------ENMKQKTSATVQKDELRTCTADSKATA 1178
Query: 485 PEESPGKRHVQTRGPSASDKPSQETLTRK-----RVSASSPTTKD 524
P PG R S + TLT+K VS +P K+
Sbjct: 1179 PAYKPG-RGTGVNSNSEKHADHRSTLTKKMHIQSAVSKMNPGEKE 1222
Score = 39.3 bits (90), Expect = 0.019
Identities = 86/461 (18%), Positives = 161/461 (34%), Gaps = 51/461 (11%)
Query: 124 VVQTVKHIHVKAFS-KDQNIVGNARPKETDHKSLSSSP------DKR---EKFKEQRKAT 173
+++T+ ++ +A + + NA+ E K L S P DK E ++ K+T
Sbjct: 204 ILETITSLNQEASAARASTETSNAKTSERASKKLPSQPTTDTSTDKERTSEDMADKEKST 263
Query: 174 VN--------VKKDKE--DKPLKTEKRPKQPDKEGKLICSEKGKVSEKSLPKNEKEDKEN 223
+ K +E D P E+ + LI K E S KN+ DK
Sbjct: 264 ADSGGEGLETAPKSEEFSDLPCPVEEIKNYTKEHNNLILLNKDVQQESSEQKNKSTDKGE 323
Query: 224 ISENDREYSGDAQVDKKPEN----DIVKSPQENLREPKRKRGRPPSIAPTAVDSNSQTLQ 279
+ D G+ + +KK + D K ++ + K+ + + + S + +
Sbjct: 324 -KKPDSNEKGERKKEKKEKTEKKFDHSKKSEDTQKVKDEKQAKEKEVESLKLPSEKNSNK 382
Query: 280 PITLELRRRKISKGCEVPLKRPRLDKNSSQEKSKNYSENTDKDLSRRRSSRLSTNGTHEI 339
T+E + S +D + S DLS T +
Sbjct: 383 AKTVEGTKEDFS----------LIDSDVDGLTDITVSSVHTSDLSSFEEDTEEEVVTSDS 432
Query: 340 LDPDLVVSDLVDTDPLQDTLSSTKESEEGQLKSALEAGQVSSALTCHSFGDGSGAAGLEL 399
++ + SD + + T + T +S EG+ KS A L + D +E
Sbjct: 433 MEEGEITSDDEEKNKQNKTKTQTSDSSEGKTKSVRHAYVHKPYLYSKYYSDSDDELTVEQ 492
Query: 400 NCPSMG----ENTMKTEPTSPLVELQEISTVEVTNTFKKTDDFGSSNAPAVDLDH----K 451
S+ E ++ + +E + E T + KT G S +VDL+
Sbjct: 493 RRQSIAKEKEERLLRRQINREKLEEKRKQKAEKTKS-SKTKGQGRS---SVDLEESSTKS 548
Query: 452 FRCKVVDCLKFFRKAKLLHYHMKYFHGMEKSLEPEESPGKRHVQTRGPSASDKPSQETLT 511
K + ++ K+L + +K E K+ Q S + E
Sbjct: 549 LEPKAARIKEVLKERKVLEKKVALSKKRKKDSRNVEENSKKKQQYEEDSKETLKTSEHCE 608
Query: 512 RKRVSASSPT----TKDKEKNKEKKFKEFVRVKPKKKKKKK 548
++++S+S K + ++ E + V + K + K
Sbjct: 609 KEKISSSKELKHVHAKSEPSKPARRLSESLHVVDENKNESK 649
Score = 30.4 bits (67), Expect = 8.8
Identities = 31/148 (20%), Positives = 62/148 (41%), Gaps = 32/148 (21%)
Query: 147 RPKETDHKSLSSSPD------KREKFKEQR---KATVNVKKDK---------EDKPLKTE 188
+P++ D ++ S + KR++ + ++ + T+ +K D E P ++
Sbjct: 2851 KPEQNDDDTIKSQEEDQPIIIKRKRGRPRKYPVETTLKMKDDSKTDTGIVTVEQSPSSSK 2910
Query: 189 KRPKQPDKEGKLICSEKGKVSEKSLPKNEKEDKENISENDREYSGDAQVDKKPENDIVKS 248
+ Q D+ K E + E+S+ ++ E+K S R +KP+ + S
Sbjct: 2911 LKVMQTDESNK----ETANLQERSISNDDGEEKIVTSVRRR--------GRKPKRSLTVS 2958
Query: 249 PQENLREPKRKRGRPPSIAPTAVDSNSQ 276
EP+RKR + S++ D Q
Sbjct: 2959 DDAESSEPERKRQK--SVSDPVEDKKEQ 2984
>gi|116268091 PHD finger protein 23 [Homo sapiens]
Length = 403
Score = 55.8 bits (133), Expect = 2e-07
Identities = 52/210 (24%), Positives = 85/210 (40%), Gaps = 41/210 (19%)
Query: 520 PTTKDKEKNKEKKFKEFVRVKPKKKKKKKKKTK---------PECPCSE---EISDTSQE 567
PT D EK R+K KK+K KK + P+ P S+ E + +E
Sbjct: 204 PTPGDGEKRS--------RIKKSKKRKLKKAERGDRLPPPGPPQAPPSDTDSEEEEEEEE 255
Query: 568 PSPPKAFAVTRCGSSHKPGVHMSPQLHGPESGHHKGKVKALEEDNLSESSSESFLWSDDE 627
+ A G + P + P+ P + H V + ++ S+E+
Sbjct: 256 EEEEEEMATVVGGEAPVPVLPTPPEAPRPPATVHPEGVPPADSESKEVGSTET------- 308
Query: 628 YGQDVDVTTNP------DEEL---DGDDRYDFEVVRCICEVQEENDFMIQCEECQCWQHG 678
QD D +++ DE++ GDD +D ++ C C MI+C C W H
Sbjct: 309 -SQDGDASSSEGEMRVMDEDIMVESGDDSWD--LITCYCRKPFAGRPMIECSLCGTWIHL 365
Query: 679 VCMGLLEENVPEKYTCYVCQD--PPGQRPG 706
C + + NVP+ + C C++ P +R G
Sbjct: 366 SCAKIKKTNVPDFFYCQKCKELRPEARRLG 395
>gi|110349788 absent, small, or homeotic 1-like [Homo sapiens]
Length = 2964
Score = 55.5 bits (132), Expect = 3e-07
Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 2/78 (2%)
Query: 627 EYGQDVDVTTNPDEELDGDDRYDFEVVRCICEVQEENDFMIQCEECQCWQHGVCMGLLEE 686
E + D + E + D +V+RCIC + ++ MIQC++C WQH CMG+ +
Sbjct: 2555 ETASEADSSETSVSEKENGHEKDDDVIRCICGLYKDEGLMIQCDKCMVWQHCDCMGVNSD 2614
Query: 687 NVPEKYTCYVCQDPPGQR 704
E Y C C P R
Sbjct: 2615 --VEHYLCEQCDPRPVDR 2630
>gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens]
Length = 1312
Score = 51.2 bits (121), Expect = 5e-06
Identities = 90/425 (21%), Positives = 165/425 (38%), Gaps = 31/425 (7%)
Query: 22 RDRLKNWYPAHIEDIDYEEGKVL--IHFKRWNHRYDEWFCWDS---PYLRPLEKIQLRKE 76
R + + Y A I+D D E G+VL +H+ WN RYDEW D P + + KI+ RK+
Sbjct: 581 RGKNQKMYEASIKDSDVEGGEVLYLVHYCGWNVRYDEWIKADKIVRPADKNVPKIKHRKK 640
Query: 77 GLHEEDGSSEFQINEQVLACWSDCRFYPAKVTAVNKDGTYTVKFYDGVVQTVKHIHVKAF 136
++ D + C P T + + + D HI
Sbjct: 641 IKNKLDKEKDKDEKYSPKNCKLRRLSKPPFQTNPSPEMVSKLDLTDAKNSDTAHIKSIEI 700
Query: 137 SKDQN--IVGNARPKETDHKSLSSSPDKREKFKEQRKATVNVKKDKEDKPLKTEKRPKQP 194
+ N + ++++ + + D KE+ K ++ ++ D K E+
Sbjct: 701 TSILNGLQASESSAEDSEQEDERGAQDMDNNGKEESKID-HLTNNRNDLISKEEQNSSSL 759
Query: 195 DKEGKLICSEKGKVSEKSLPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSPQENLR 254
+E K+ P+ ++D E +SE D +Y D +V KK D+ K +
Sbjct: 760 LEENKVHADLVISKPVSKSPERLRKDIEVLSE-DTDYEED-EVTKK-RKDVKKDTTDKSS 816
Query: 255 EPKRKRGRPPSIAPTAVDSNSQTLQPITLELRRRKISKGCEVPLKRPRLDKNSSQEKSKN 314
+P+ KRG+ + +T P E + + C D++ + K+K
Sbjct: 817 KPQIKRGKR---RYCNTEECLKTGSPGKKEEKAKNKESLCMENSSNSSSDEDEEETKAKM 873
Query: 315 YSENTDKDLSRRRSSRLST---NGTHEILDPDLVVSDLVDTDPLQDTLSSTKESEEGQLK 371
L +R S +T +G E+ + + + + D + L +++ + +
Sbjct: 874 TPTKKYNGLEEKRKSLRTTGFYSGFSEVAEKRIKLLNNSD-----ERLQNSRAKDRKDVW 928
Query: 372 SALEAGQVSSALTCHSFGDGSGAAGLELNCPS----MGENTMKT----EPTSPLVELQEI 423
S+++ GQ F D A P+ + E +++T E SP VEL++
Sbjct: 929 SSIQ-GQWPKKTLKELFSDSDTEAAASPPHPAPEEGVAEESLQTVAEEESCSPSVELEKP 987
Query: 424 STVEV 428
V V
Sbjct: 988 PPVNV 992
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 50.1 bits (118), Expect = 1e-05
Identities = 45/180 (25%), Positives = 74/180 (41%), Gaps = 28/180 (15%)
Query: 523 KDKEKNKEKKFKEFVRVKPKKKKKK-KKKTKPECPCSEEISDTSQEPSPPKAFAVTRCGS 581
KD + +++ K +++K +K + + T PC P+PP +
Sbjct: 2618 KDLQIEVQEELKRDLKIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPPS-------P 2670
Query: 582 SHKPGVHMSPQLHGPESGHHKGKVKALEEDNLSESSSESFLWSDDEYGQDVDVTTNPDEE 641
P V + L P K K EE + S S + + S TT+ + +
Sbjct: 2671 PPPPAVQHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMIS----------TTSKETK 2720
Query: 642 LDGDDRYDFEVVRCICEVQ-EENDFMIQCEECQCWQHGVCMGLL--EENVPEKYTCYVCQ 698
D + CIC+ +E+ F I C+ CQ W HG C+G+L E + ++Y C CQ
Sbjct: 2721 KDTK-------LYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQ 2773
Score = 30.8 bits (68), Expect = 6.7
Identities = 57/261 (21%), Positives = 97/261 (37%), Gaps = 37/261 (14%)
Query: 164 EKFKEQRKATVNVKKDKEDKPLKTEKRPKQPDKEGKL--ICSEKGKVSEKSLP------K 215
E+ +E+ +++ +D +K + K E L I ++KG + P K
Sbjct: 521 EEMREEIHRHMDITEDLTNKARGSNKSFLAAANEEILESIRAKKGDIDNVKSPEETEKDK 580
Query: 216 NEKEDKENISENDREYSGDAQV-----DKKPENDIVKSPQENLREPKRKRGRPPSIAPTA 270
NE E+ +E +RE D + DK P++D + E EP + S++
Sbjct: 581 NETENDSKDAEKNREEFEDQSLEKDSDDKTPDDDPEQGKSE---EPTEVGDKGNSVSANL 637
Query: 271 VDSNSQTLQPITLELRRRKISKGC--EVPLKRPRLDKNSSQEKSKNYSENTDKDLSRRRS 328
D+ + T R GC E P +K + E ++ E +K +
Sbjct: 638 GDNTTNATSEETSPSEGRS-PVGCLSETPDSSNMAEKKVASELPQDVPEEPNKTCESSNT 696
Query: 329 SRLST---------NGTHEI----LDPDLVVSDLVDTDPLQDTLSSTKESEEGQLKSALE 375
S +T N + E+ + D + + T S +E G KS
Sbjct: 697 SATTTSIQPNLENSNSSSELNSSQSESAKAADDPENGERESHTPVSIQEEIVGDFKSEKS 756
Query: 376 AGQVSSALTCHSFGDGSGAAG 396
G++S S G G GA+G
Sbjct: 757 NGELS-----ESPGAGKGASG 772
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 50.1 bits (118), Expect = 1e-05
Identities = 45/180 (25%), Positives = 74/180 (41%), Gaps = 28/180 (15%)
Query: 523 KDKEKNKEKKFKEFVRVKPKKKKKK-KKKTKPECPCSEEISDTSQEPSPPKAFAVTRCGS 581
KD + +++ K +++K +K + + T PC P+PP +
Sbjct: 2635 KDLQIEVQEELKRDLKIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPPS-------P 2687
Query: 582 SHKPGVHMSPQLHGPESGHHKGKVKALEEDNLSESSSESFLWSDDEYGQDVDVTTNPDEE 641
P V + L P K K EE + S S + + S TT+ + +
Sbjct: 2688 PPPPAVQHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMIS----------TTSKETK 2737
Query: 642 LDGDDRYDFEVVRCICEVQ-EENDFMIQCEECQCWQHGVCMGLL--EENVPEKYTCYVCQ 698
D + CIC+ +E+ F I C+ CQ W HG C+G+L E + ++Y C CQ
Sbjct: 2738 KDTK-------LYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQ 2790
Score = 30.8 bits (68), Expect = 6.7
Identities = 53/191 (27%), Positives = 72/191 (37%), Gaps = 36/191 (18%)
Query: 218 KEDKENISENDRE---YSGDAQV-------DKKP-ENDIVKSPQENLREPKRKRGRPPSI 266
+ED EN EN+++ YS Q+ DK E ++ K +E E R +
Sbjct: 480 EEDTEN--ENEKKIWYYSTKVQLAELIDCLDKDYWEAELCKILEEMREEIHRHMDITEDL 537
Query: 267 APTAVDSNSQTLQPITLE-LRRRKISKGCEVPLKRPRLDKNSSQEKSKNYSENTDKDLSR 325
A SN L E L + KG +K P EK KN +EN KD +
Sbjct: 538 TNKARGSNKSFLAAANEEILESIRAKKGDIDNVKSPE-----ETEKDKNETENDSKDAEK 592
Query: 326 RRSSRLSTNGTHEILDPDLVVSDLVDTDPLQDTLSSTKESEEGQLKSALEAGQVSSALTC 385
R E + + D D P D +SE G KS G++S
Sbjct: 593 NR----------EEFEDQSLEKDSDDKTPDDD--PEQGKSEVGDFKSEKSNGELS----- 635
Query: 386 HSFGDGSGAAG 396
S G G GA+G
Sbjct: 636 ESPGAGKGASG 646
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 48.1 bits (113), Expect = 4e-05
Identities = 101/524 (19%), Positives = 197/524 (37%), Gaps = 84/524 (16%)
Query: 149 KETDHKSLSSSPDKREKFKEQRKATVNVKKDKEDKPLKTEKRPKQPDKE---GKLICSEK 205
+ET + + +K K + + K V K+DKP+KTE +P +KE + K
Sbjct: 563 EETPEVTKVNHVEKPPKVESKEKVMV-----KKDKPIKTETKPSVTEKEVPSKEEPSPVK 617
Query: 206 GKVSEKSL----PKNEKEDKENISENDREYSGDAQVDK-KPENDIV----KSPQENLREP 256
+V+EK PK KE + + + + D + +K KP+ ++ K+P + +P
Sbjct: 618 AEVAEKQATDVKPKAAKE--KTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKP 675
Query: 257 KRKRGRPPSIAPTAVDSNSQTLQPITLELRRRKISKGCEVPLKRPRLDKNSSQEKSKNYS 316
K++ + + + + + E +++ K + K + + +++ K
Sbjct: 676 KKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVK---KEEKKEVKKEEKEPKKEI 732
Query: 317 ENTDKDLSRRRSSRLSTNGTHEILDPDLVVSDLVDTDPLQDTLSSTKESEEGQLKSALEA 376
+ KD +++ S+ LS L P + + +D++++ K E+G++K +
Sbjct: 733 KKLPKD-AKKSSTPLSEAKKPAALKPKVPKK---EESVKKDSVAAGKPKEKGKIKVIKKE 788
Query: 377 GQVSSALTCHSFGDGS------GAAGLELNCPSM---GENTMKTEPTSPLVELQEISTVE 427
G+ + A+ + G G+ AAG+ P+ E ++ + P + +E+ E
Sbjct: 789 GKAAEAVAA-AVGTGATTAAVMAAAGIAAIGPAKELEAERSLMSSPEDLTKDFEELKAEE 847
Query: 428 VTNTFKKTDDFGSSNAPAVDLDHKFRCKVVDCLKFFRKAKLLHYHMKYFHGMEKSLEPEE 487
V D P ++L + D K + Y ++ + K P E
Sbjct: 848 V--------DVTKDIKPQLEL-------IEDEEKLKETEPVEAYVIQKEREVTKG--PAE 890
Query: 488 SPGKRHVQTRGPSASDKPSQETLTRKRVSASSPTTKDKEKNKEKKFKEFVRVKPKKKKKK 547
SP + T G ++ +E + V +K +++ F+E
Sbjct: 891 SPDEGITTTEGEGECEQTPEEL---EPVEKQGVDDIEKFEDEGAGFEE------------ 935
Query: 548 KKKTKPECPCSEEISDTSQEPSPPKAFAVTRCGSSHKPGVHMSPQLHGPESGHHKGKVKA 607
S E D ++ +A G H V +S H P K +A
Sbjct: 936 ----------SSETGDYEEKAETEEAEEPEEDGEEH---VCVSASKHSPTEDEESAKAEA 982
Query: 608 LEEDNLSESSSESFLWSDDEYGQDVDVTTNPDEELDGDDRYDFE 651
D ES DD +D+D E ++ D E
Sbjct: 983 ---DAYIREKRESVASGDDRAEEDMDEAIEKGEAEQSEEEADEE 1023
Score = 40.8 bits (94), Expect = 0.007
Identities = 39/179 (21%), Positives = 83/179 (46%), Gaps = 8/179 (4%)
Query: 137 SKDQNIVGNARPKETDHKSLSSSPDKREKFKEQRKATVNVKKDKEDKPLK--TEKRPKQP 194
SK++ A E + K + K++ K KK++++KP K +K K P
Sbjct: 609 SKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTP 668
Query: 195 DKEGKLICSEKGKVSEKSLPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSPQENLR 254
K+ + +K +V ++ + +KE+K+ + ++ + +V K+ + + K ++ +
Sbjct: 669 IKKEEK--PKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEK 726
Query: 255 EPKRKRGRPPSIAPTAVDSNSQTLQPITLELRRRKISKGCEVPLKRPRLDKNSSQEKSK 313
EPK++ + P A + S+ +P L + K+ K E +K+ + +EK K
Sbjct: 727 EPKKEIKKLPKDAKKSSTPLSEAKKPAAL---KPKVPKK-EESVKKDSVAAGKPKEKGK 781
Score = 35.0 bits (79), Expect = 0.36
Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 5/88 (5%)
Query: 499 PSASDKPSQETLTRKRVSASSP-TTKDKEKNKEKKFKEFVRVKPKKKKKKKKKTKPECPC 557
P+A PS+ RK +P TK K K + +V KK K K +TKP
Sbjct: 547 PAAKPLPSKSV--RKESKEETPEVTKVNHVEKPPKVESKEKVMVKKDKPIKTETKPSV-- 602
Query: 558 SEEISDTSQEPSPPKAFAVTRCGSSHKP 585
+E+ + +EPSP KA + + KP
Sbjct: 603 TEKEVPSKEEPSPVKAEVAEKQATDVKP 630
>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
Length = 2240
Score = 47.8 bits (112), Expect = 5e-05
Identities = 49/207 (23%), Positives = 80/207 (38%), Gaps = 18/207 (8%)
Query: 498 GP-SASDKPSQETLTRKRVSASSPTTKDKEKNKEKKFKEFVRVKPKKKKKKKKKTKPECP 556
GP SAS + + ++V + + + + ++ + ++K++++ +P
Sbjct: 124 GPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERPLKG 183
Query: 557 CSEEISDTSQEPSPPKAFAVTRCGSSHKPGVHMSPQLHGPESGHHKGKVKALEEDNLSES 616
+ +E P A V S GV S Q + G K E L
Sbjct: 184 IQSRLRKKRREEGP--AETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEGK 241
Query: 617 SSESFLWSDDEYGQDVDVTTNPDEELDGDDRYDFEVVRCICEVQEENDFMIQCEECQCWQ 676
+++ D+E G P E +G YD + CIC N FMI C+ C+ W
Sbjct: 242 AAQDI--KDEEPGD----LGRPKPECEG---YDPNALYCICRQPHNNRFMICCDRCEEWF 292
Query: 677 HGVCMGLLE------ENVPEKYTCYVC 697
HG C+G+ E E E Y C C
Sbjct: 293 HGDCVGISEARGRLLERNGEDYICPNC 319
>gi|71044477 death inducer-obliterator 1 isoform b [Homo sapiens]
Length = 1189
Score = 47.8 bits (112), Expect = 5e-05
Identities = 49/207 (23%), Positives = 80/207 (38%), Gaps = 18/207 (8%)
Query: 498 GP-SASDKPSQETLTRKRVSASSPTTKDKEKNKEKKFKEFVRVKPKKKKKKKKKTKPECP 556
GP SAS + + ++V + + + + ++ + ++K++++ +P
Sbjct: 124 GPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERPLKG 183
Query: 557 CSEEISDTSQEPSPPKAFAVTRCGSSHKPGVHMSPQLHGPESGHHKGKVKALEEDNLSES 616
+ +E P A V S GV S Q + G K E L
Sbjct: 184 IQSRLRKKRREEGP--AETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEGK 241
Query: 617 SSESFLWSDDEYGQDVDVTTNPDEELDGDDRYDFEVVRCICEVQEENDFMIQCEECQCWQ 676
+++ D+E G P E +G YD + CIC N FMI C+ C+ W
Sbjct: 242 AAQDI--KDEEPGD----LGRPKPECEG---YDPNALYCICRQPHNNRFMICCDRCEEWF 292
Query: 677 HGVCMGLLE------ENVPEKYTCYVC 697
HG C+G+ E E E Y C C
Sbjct: 293 HGDCVGISEARGRLLERNGEDYICPNC 319
>gi|18375619 death inducer-obliterator 1 isoform a [Homo sapiens]
Length = 562
Score = 47.8 bits (112), Expect = 5e-05
Identities = 49/207 (23%), Positives = 80/207 (38%), Gaps = 18/207 (8%)
Query: 498 GP-SASDKPSQETLTRKRVSASSPTTKDKEKNKEKKFKEFVRVKPKKKKKKKKKTKPECP 556
GP SAS + + ++V + + + + ++ + ++K++++ +P
Sbjct: 124 GPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERPLKG 183
Query: 557 CSEEISDTSQEPSPPKAFAVTRCGSSHKPGVHMSPQLHGPESGHHKGKVKALEEDNLSES 616
+ +E P A V S GV S Q + G K E L
Sbjct: 184 IQSRLRKKRREEGP--AETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEGK 241
Query: 617 SSESFLWSDDEYGQDVDVTTNPDEELDGDDRYDFEVVRCICEVQEENDFMIQCEECQCWQ 676
+++ D+E G P E +G YD + CIC N FMI C+ C+ W
Sbjct: 242 AAQDI--KDEEPGD----LGRPKPECEG---YDPNALYCICRQPHNNRFMICCDRCEEWF 292
Query: 677 HGVCMGLLE------ENVPEKYTCYVC 697
HG C+G+ E E E Y C C
Sbjct: 293 HGDCVGISEARGRLLERNGEDYICPNC 319
>gi|18375617 death inducer-obliterator 1 isoform a [Homo sapiens]
Length = 562
Score = 47.8 bits (112), Expect = 5e-05
Identities = 49/207 (23%), Positives = 80/207 (38%), Gaps = 18/207 (8%)
Query: 498 GP-SASDKPSQETLTRKRVSASSPTTKDKEKNKEKKFKEFVRVKPKKKKKKKKKTKPECP 556
GP SAS + + ++V + + + + ++ + ++K++++ +P
Sbjct: 124 GPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERPLKG 183
Query: 557 CSEEISDTSQEPSPPKAFAVTRCGSSHKPGVHMSPQLHGPESGHHKGKVKALEEDNLSES 616
+ +E P A V S GV S Q + G K E L
Sbjct: 184 IQSRLRKKRREEGP--AETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEGK 241
Query: 617 SSESFLWSDDEYGQDVDVTTNPDEELDGDDRYDFEVVRCICEVQEENDFMIQCEECQCWQ 676
+++ D+E G P E +G YD + CIC N FMI C+ C+ W
Sbjct: 242 AAQDI--KDEEPGD----LGRPKPECEG---YDPNALYCICRQPHNNRFMICCDRCEEWF 292
Query: 677 HGVCMGLLE------ENVPEKYTCYVC 697
HG C+G+ E E E Y C C
Sbjct: 293 HGDCVGISEARGRLLERNGEDYICPNC 319
>gi|11225260 DNA topoisomerase I [Homo sapiens]
Length = 765
Score = 47.4 bits (111), Expect = 7e-05
Identities = 51/209 (24%), Positives = 85/209 (40%), Gaps = 37/209 (17%)
Query: 130 HIHVKAFSKDQNIVGNARPKETDHKSLSSSPDKREKFKEQRKATVNVKKDKE-DKPLKTE 188
H+H D I + R ++ HK D+ + KE +K +KD+E K +E
Sbjct: 5 HLH-----NDSQIEADFRLNDS-HKHKDKHKDREHRHKEHKK-----EKDREKSKHSNSE 53
Query: 189 KRPKQPDKEGKLICSEKGKVSEKSLPKNEKEDKENISENDREYSGDAQVDKKPENDIVKS 248
+ + + K K SEK K++ DKE E SGDA++ K+ EN
Sbjct: 54 HKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSP 113
Query: 249 PQ---------------ENLREPKRKRGRPPS-IAPTAVDSNSQTLQPITLELRRRKISK 292
PQ E+++ KR R + P + + T + ++RK+ +
Sbjct: 114 PQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTED------TKKEKKRKLEE 167
Query: 293 GCEVPLKRPRLDKNSSQEKSKNYSENTDK 321
+ LK+P KN ++K +N K
Sbjct: 168 EEDGKLKKP---KNKDKDKKVPEPDNKKK 193
Score = 33.9 bits (76), Expect = 0.80
Identities = 32/106 (30%), Positives = 43/106 (40%), Gaps = 13/106 (12%)
Query: 472 HMKYFHGMEKSLEPEESPGKRHVQTRGPSASDKPSQETLTRKRVSASSPTTKDKEK--NK 529
H H EK E + H S+K +E K SS KDK K +K
Sbjct: 33 HRHKEHKKEKDREKSKHSNSEHKD------SEKKHKEKEKTKHKDGSSEKHKDKHKDRDK 86
Query: 530 EKKFKEFVRVKPKKKKKKKKKTKPECPCSEEISDTSQEPS---PPK 572
EK+ +E VR K KK+K+ P +I D ++ PPK
Sbjct: 87 EKRKEEKVRASGDAKIKKEKENGFSSP--PQIKDEPEDDGYFVPPK 130
>gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]
Length = 1007
Score = 47.4 bits (111), Expect = 7e-05
Identities = 53/207 (25%), Positives = 88/207 (42%), Gaps = 37/207 (17%)
Query: 131 IHVKAFSKDQN---IVGNARPKETDHKSLS------SSPDKREKFKEQRKATVNVKKDKE 181
I K+ SKD+ I+ +R ++ KS S S D+R + KE++ + DKE
Sbjct: 265 IEDKSKSKDRKKSPIINESRSRDRGKKSRSPVDLRGKSKDRRSRSKERKSK--RSETDKE 322
Query: 182 DKPLKTEKRPKQPDKEGKLICSEKGKVSEKSLPKNEKEDKENISENDREYSGDAQVDKKP 241
KP+K+ + KE + G+ ++ + DK S
Sbjct: 323 KKPIKSPSKDASSGKENRSPSRRPGRSPKRRSLSPKPRDKSRRS---------------- 366
Query: 242 ENDIVKSPQENLREPKRKRGRPPSIAPTAVDSNSQTLQPITLELRRRKISKGCEVPLKRP 301
+SP N R K+ + +++P + S++L+ E RR++S P RP
Sbjct: 367 -----RSPLLNDRRSKQSKSPSRTLSP-GRRAKSRSLERKRREPERRRLSS----PRTRP 416
Query: 302 RLDKNSSQEKSKNYSENTDKDLSRRRS 328
R D S +E+SK+ S +RRRS
Sbjct: 417 RDDILSRRERSKDASPINRWSPTRRRS 443
Score = 36.6 bits (83), Expect = 0.12
Identities = 59/298 (19%), Positives = 108/298 (36%), Gaps = 50/298 (16%)
Query: 72 QLRKEGLHEEDGSSEFQINEQVLACWSDCRFYPAKVTAVNKDGTYTVKFYDGVVQTVKHI 131
Q +E ED +SE INE+ D + NK + K + + KH
Sbjct: 7 QSLREQPEMEDANSEKSINEENGEVSED--------QSQNKHSRHKKKKHKHRSKHKKHK 58
Query: 132 HVKAFSKDQNIVGNARPKETDHKSL-------SSSPDKREKFK--------EQRKATVNV 176
H KD+ + K+ K + SP KR K E+++A +
Sbjct: 59 HSSEEDKDKKHKHKHKHKKHKRKEIIDASDKEGMSPAKRTKLDDLALLEDLEKQRALIKA 118
Query: 177 KKDKE---------------------DKPLKTEKRPKQPDKEGKLICSEKGKVSEKSLPK 215
+ D E ++ + ++ + ++ S KGK+ L
Sbjct: 119 ELDNELMEGKVQSGMGLILQGYESGSEEEGEIHEKARNGNRSSTRSSSTKGKLE---LVD 175
Query: 216 NEKEDKENISENDREYSGDAQVDKKPEN--DIVKSPQENLREPKRKRGRPPSIAPTAVDS 273
N+ K+ +E + KK + +IVK + +RK+ + PS + D
Sbjct: 176 NKITTKKRSKSRSKERTRHRSDKKKSKGGIEIVKEKTTRSKSKERKKSKSPSKRSKSQDQ 235
Query: 274 NSQTLQPITLELRRRKISKGCEVPLKRPRL-DKNSSQEKSKNYSENTDKDLSRRRSSR 330
++ P + KI K + ++ DK+ S+++ K+ N + R + SR
Sbjct: 236 ARKSKSPTLRRRSQEKIGKARSPTDDKVKIEDKSKSKDRKKSPIINESRSRDRGKKSR 293
Score = 35.0 bits (79), Expect = 0.36
Identities = 56/265 (21%), Positives = 97/265 (36%), Gaps = 37/265 (13%)
Query: 305 KNSSQEKSKNYSENTDKDLSRRRSSRLSTNGTHEILDPDLVVSDLVDTDP---------- 354
K+ S+ K +S DKD + + + EI+D SD P
Sbjct: 49 KHRSKHKKHKHSSEEDKDKKHKHKHKHKKHKRKEIID----ASDKEGMSPAKRTKLDDLA 104
Query: 355 LQDTLSSTKESEEGQLKSALEAGQVSS--ALTCHSFGDGSGAAGLELNCPSMGENTMKTE 412
L + L + + +L + L G+V S L + GS G E++ + N T
Sbjct: 105 LLEDLEKQRALIKAELDNELMEGKVQSGMGLILQGYESGSEEEG-EIHEKARNGNRSSTR 163
Query: 413 PTSPLVELQEISTVEVTNTFKKTDDFGSSNAPAVDLDHKFRCKVVDCLKFFRKAKLLHYH 472
+S +L+ V+ T KK S D K ++ +K
Sbjct: 164 SSSTKGKLE---LVDNKITTKKRSKSRSKERTRHRSDKKKSKGGIEIVK----------- 209
Query: 473 MKYFHGMEKSLEPEESPGKRHVQTRGPSASDKPSQETLTRKRV-SASSPT-----TKDKE 526
K K + +SP KR S P+ +++++ A SPT +DK
Sbjct: 210 EKTTRSKSKERKKSKSPSKRSKSQDQARKSKSPTLRRRSQEKIGKARSPTDDKVKIEDKS 269
Query: 527 KNKEKKFKEFVRVKPKKKKKKKKKT 551
K+K++K + + + KK ++
Sbjct: 270 KSKDRKKSPIINESRSRDRGKKSRS 294
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 46.2 bits (108), Expect = 2e-04
Identities = 97/457 (21%), Positives = 162/457 (35%), Gaps = 78/457 (17%)
Query: 144 GNARPKETDHKSLSSSPDKREKFKEQRKATVNVKKDKEDKPLKTEKRPKQPDKEGKLICS 203
G A K ++ S S D ++ ++Q+K V K KP K K P K+ K S
Sbjct: 117 GKAAAKASESSSSEESSDDDDE-EDQKKQPVQ----KGVKP--QAKAAKAPPKKAKSSDS 169
Query: 204 EKGKVSEKSLPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSPQENLRE-PKRKRGR 262
+ SE PKN+K ++ + K+P + R PK G+
Sbjct: 170 DSDSSSEDEPPKNQKPKITPVTVKAQ----------------TKAPPKPARAAPKIANGK 213
Query: 263 PPSIAPTAVDSNSQ--------TLQPITLELRRRKISKGCEVPLKRPRLDKNSSQEKSKN 314
S + ++ S+S P +++ ++K P +SS++ S +
Sbjct: 214 AASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSD 273
Query: 315 YSENTDKDLSRRRSSRLSTNGTHEILDPDLVVSDLVDTDPLQDTLSSTKESEEGQLKSAL 374
E K + + G + + P P + +L + + + + +
Sbjct: 274 EEEEQKKPMKNKP-------GPYSSVPPP-------SAPPPKKSLGTQPPKKAVEKQQPV 319
Query: 375 EAGQVSSALTCHSFGDGSGAAGLELNCPSMGENTMKTEPTSPLVELQEISTVEVTNTFKK 434
E+ + SS D S ++ E P K P + S+ + +++
Sbjct: 320 ESSEDSS--------DESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSS 371
Query: 435 TDDFG----------SSNAPAVDLDHK-FRCKVVDCLKFFRKAKLLHYHMKYFHGMEKSL 483
DD SSN PAV + KLL E+S
Sbjct: 372 EDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESS 431
Query: 484 EPEESPGKRHVQTRGPSASDK-----PSQETLTRKRVSASSPTTKDKEKNKEKKFKEFVR 538
EE K+ V T P A+ K P+++ R S+S + E+ +EK K V+
Sbjct: 432 SSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVK 491
Query: 539 VKPKK--------KKKKKKKTKPECPCSEEISDTSQE 567
KP+K K KK K E S D+S+E
Sbjct: 492 KKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEE 528
Score = 40.8 bits (94), Expect = 0.007
Identities = 85/446 (19%), Positives = 152/446 (34%), Gaps = 68/446 (15%)
Query: 204 EKGKVSEKSLPKN---EKEDKENISENDREYSGDAQVDKKPENDIVKSPQENLREPKRKR 260
+ KV E+ L N K+ K+ S +D E S + E ++ P + P ++
Sbjct: 59 KSAKVPERKLQANGPVAKKAKKKASSSDSEDSSEE------EEEVQGPPAKKAAVPAKRV 112
Query: 261 GRPPSIAPTAVDSNSQTLQPIT----LELRRRKISKGCEVPLKRPRLDKNSSQEKSKNYS 316
G PP A +S + + + +++ + KG + K + + +K+K S
Sbjct: 113 GLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAK----APPKKAK--S 166
Query: 317 ENTDKDLSRRRSSRLSTNGTHEILDPDLVVSDLVDTDPLQDTLSSTKESEEGQLKSALEA 376
++D D S D P T + + Q K+ +
Sbjct: 167 SDSDSDSSSE------------------------DEPPKNQKPKITPVTVKAQTKAPPKP 202
Query: 377 GQVSSALTCHSFGDGSGAAGLELNCPSMGENTMKTEPTSPLVELQEISTVEVTNTFKKTD 436
+ + + S ++ + E P + + Q ++ V T
Sbjct: 203 ARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTR 262
Query: 437 DFGSSNAPAVDLDHKFRCKVVDCLKFFRKAKLLHYHMKYFHGMEKSLEPEESPG-KRHVQ 495
SS + D + + + MK G S+ P +P K+ +
Sbjct: 263 KSSSSEDSSSDEEEEQKKP-----------------MKNKPGPYSSVPPPSAPPPKKSLG 305
Query: 496 TRGPSASDKPSQETLTRKRVSASSPTTKDKEKNKEKKFKEFVRVKPKKKKKKKKKTKPEC 555
T+ P + + Q + + S S ++ ++EK K V K K E
Sbjct: 306 TQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTK----AVVSKATTKPPPAKKAAES 361
Query: 556 PCSEEISDTSQEPSPPKAFAVTRCGSSHKPGVHMSPQLHGPESGHHK---GKVKALEEDN 612
SD+S++ P A T SS+KP V P + + G K L
Sbjct: 362 SSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKA 421
Query: 613 LSESSSESFLWSDDEYGQDVDVTTNP 638
S SS E S++E + + TT P
Sbjct: 422 DSSSSEEESSSSEEEKTKKMVATTKP 447
>gi|7657218 bromodomain-containing protein 4 isoform short [Homo
sapiens]
Length = 722
Score = 46.2 bits (108), Expect = 2e-04
Identities = 47/189 (24%), Positives = 75/189 (39%), Gaps = 22/189 (11%)
Query: 153 HKSLSSSPDKREKFKEQRKATVNVKKDKEDKPLKTEKRPKQPDKEGKLICSEKGKVSEKS 212
+K DK+EK KE+ K V+++K+ K + + + + S+K KS
Sbjct: 534 NKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKS 593
Query: 213 LPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSPQENL---------REPKRKRGRP 263
P E +E Y Q+ DI K P E L REP K P
Sbjct: 594 KPPPTYESEEEDKCKPMSYEEKRQLSL----DINKLPGEKLGRVVHIIQSREPSLKNSNP 649
Query: 264 PSIAPTAVDSNSQTLQPITLELRRRKISKGCEVPLKRP---RLDKNSSQEKSKNYSENTD 320
I + + +TL+P TL R ++ C ++P ++D + K K +S +
Sbjct: 650 DEI-----EIDFETLKPSTLRELERYVT-SCLRKKRKPQAEKVDVIAGSSKMKGFSSSES 703
Query: 321 KDLSRRRSS 329
+ S SS
Sbjct: 704 ESSSESSSS 712
Score = 33.1 bits (74), Expect = 1.4
Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 8/98 (8%)
Query: 484 EPEESPGKRHVQTRGPSASDKPSQETLTRKRVS----ASSPTTKDKEKNKEKKFKEFVRV 539
+P +P + VQ+ P + P Q T+K V ++PTT D E
Sbjct: 258 QPPPAPAPQPVQSHPPIIAATP-QPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPE---P 313
Query: 540 KPKKKKKKKKKTKPECPCSEEISDTSQEPSPPKAFAVT 577
K K ++++ ++P P +++ D+ Q P+P K+ V+
Sbjct: 314 KTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVS 351
Score = 32.0 bits (71), Expect = 3.0
Identities = 34/161 (21%), Positives = 65/161 (40%), Gaps = 14/161 (8%)
Query: 495 QTRGPSASDKPSQETLTRKRVSASSPTTKDKEKNKEKKFKEFVRVKPKKKKKKKKKTKPE 554
+ R ++ Q ++++A S ++K K KEK KE KKK+K K+K + E
Sbjct: 505 EERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKE------KKKEKHKRKEEVE 558
Query: 555 CPCSEEISDTSQEPSPPKAFAVTRCGSSHKPGVHMSPQLHGPE---SGHHKGKVKALEED 611
E ++EP PPK +S+ +P P + K K + +
Sbjct: 559 ----ENKKSKAKEP-PPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYE 613
Query: 612 NLSESSSESFLWSDDEYGQDVDVTTNPDEELDGDDRYDFEV 652
+ S + ++ G+ V + + + L + + E+
Sbjct: 614 EKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEI 654
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 46.2 bits (108), Expect = 2e-04
Identities = 47/189 (24%), Positives = 75/189 (39%), Gaps = 22/189 (11%)
Query: 153 HKSLSSSPDKREKFKEQRKATVNVKKDKEDKPLKTEKRPKQPDKEGKLICSEKGKVSEKS 212
+K DK+EK KE+ K V+++K+ K + + + + S+K KS
Sbjct: 534 NKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKS 593
Query: 213 LPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSPQENL---------REPKRKRGRP 263
P E +E Y Q+ DI K P E L REP K P
Sbjct: 594 KPPPTYESEEEDKCKPMSYEEKRQLSL----DINKLPGEKLGRVVHIIQSREPSLKNSNP 649
Query: 264 PSIAPTAVDSNSQTLQPITLELRRRKISKGCEVPLKRP---RLDKNSSQEKSKNYSENTD 320
I + + +TL+P TL R ++ C ++P ++D + K K +S +
Sbjct: 650 DEI-----EIDFETLKPSTLRELERYVT-SCLRKKRKPQAEKVDVIAGSSKMKGFSSSES 703
Query: 321 KDLSRRRSS 329
+ S SS
Sbjct: 704 ESSSESSSS 712
Score = 33.1 bits (74), Expect = 1.4
Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 8/98 (8%)
Query: 484 EPEESPGKRHVQTRGPSASDKPSQETLTRKRVS----ASSPTTKDKEKNKEKKFKEFVRV 539
+P +P + VQ+ P + P Q T+K V ++PTT D E
Sbjct: 258 QPPPAPAPQPVQSHPPIIAATP-QPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPE---P 313
Query: 540 KPKKKKKKKKKTKPECPCSEEISDTSQEPSPPKAFAVT 577
K K ++++ ++P P +++ D+ Q P+P K+ V+
Sbjct: 314 KTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVS 351
Score = 32.0 bits (71), Expect = 3.0
Identities = 34/161 (21%), Positives = 65/161 (40%), Gaps = 14/161 (8%)
Query: 495 QTRGPSASDKPSQETLTRKRVSASSPTTKDKEKNKEKKFKEFVRVKPKKKKKKKKKTKPE 554
+ R ++ Q ++++A S ++K K KEK KE KKK+K K+K + E
Sbjct: 505 EERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKE------KKKEKHKRKEEVE 558
Query: 555 CPCSEEISDTSQEPSPPKAFAVTRCGSSHKPGVHMSPQLHGPE---SGHHKGKVKALEED 611
E ++EP PPK +S+ +P P + K K + +
Sbjct: 559 ----ENKKSKAKEP-PPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYE 613
Query: 612 NLSESSSESFLWSDDEYGQDVDVTTNPDEELDGDDRYDFEV 652
+ S + ++ G+ V + + + L + + E+
Sbjct: 614 EKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEI 654
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 45.4 bits (106), Expect = 3e-04
Identities = 28/114 (24%), Positives = 58/114 (50%), Gaps = 6/114 (5%)
Query: 149 KETDHKSLSSSPDKREKFKEQRKATVNVKKDKEDKPLKTEKRPKQPDKEGKLICSEKGKV 208
+ET+ + +++E +++++ +K+K+ K +TEKR ++ ++E K K K
Sbjct: 11 EETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKK 70
Query: 209 SEKSLPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSPQENLREPKRKRGR 262
E+ + E+E++E E ++E + KK + +E E K+KR R
Sbjct: 71 EEEEREEEEEEEEEEKEEEEKEEGRRRKKKKK------RRRKEEEEEKKKKRRR 118
Score = 43.5 bits (101), Expect = 0.001
Identities = 24/114 (21%), Positives = 59/114 (51%)
Query: 147 RPKETDHKSLSSSPDKREKFKEQRKATVNVKKDKEDKPLKTEKRPKQPDKEGKLICSEKG 206
+ KET+ + ++ E+ + +RK K+ +++K KT++ K+ +KE + ++
Sbjct: 6 KKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRK 65
Query: 207 KVSEKSLPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSPQENLREPKRKR 260
+ +K + E+E++E E + E + + KK + K +E ++ +R++
Sbjct: 66 RKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119
Score = 37.7 bits (86), Expect = 0.055
Identities = 25/107 (23%), Positives = 55/107 (51%), Gaps = 10/107 (9%)
Query: 162 KREKFKEQRKATVNVKKDKEDKPLKTEKRPKQPDKEGKLICSEKGKVSEKSLPKNEKED- 220
K++K K++ + T ++ +E++ + +++ K+ +K + +K K +EK K E+E
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61
Query: 221 -----KENISENDREYSGDAQVDKKPENDIVKSPQENLREPKRKRGR 262
K+ E +RE + + ++K E + +E R K+K+ R
Sbjct: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEE----KEEGRRRKKKKKRR 104
Score = 37.0 bits (84), Expect = 0.094
Identities = 26/88 (29%), Positives = 42/88 (47%), Gaps = 17/88 (19%)
Query: 480 EKSLEPEESPGKRHVQTRGPSASDKPSQETLTRKRVSASSPTTKDKEKNKEKKFKEFVRV 539
E++ E EE GKR ++ +++ TK+ EK KEK+ +E
Sbjct: 17 EETEEEEEKEGKR-------------KEKRKEKRKEKEKKKKTKETEKRKEKEEEE---- 59
Query: 540 KPKKKKKKKKKTKPECPCSEEISDTSQE 567
K +K+K+KKKK + E EE + +E
Sbjct: 60 KKRKRKRKKKKEEEEREEEEEEEEEEKE 87
Score = 32.7 bits (73), Expect = 1.8
Identities = 16/75 (21%), Positives = 38/75 (50%)
Query: 480 EKSLEPEESPGKRHVQTRGPSASDKPSQETLTRKRVSASSPTTKDKEKNKEKKFKEFVRV 539
EK E E+ + + R ++ ++ +K+ +++E+ +EK+ +E
Sbjct: 35 EKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEG 94
Query: 540 KPKKKKKKKKKTKPE 554
+ +KKKKK+++ + E
Sbjct: 95 RRRKKKKKRRRKEEE 109
Score = 31.2 bits (69), Expect = 5.2
Identities = 32/145 (22%), Positives = 59/145 (40%), Gaps = 25/145 (17%)
Query: 177 KKDKEDKPLKTEKRPKQPDKEGKLICSEKGKVSEKSLPKNEKEDKENISENDREYSGDAQ 236
KK K+ + +TE+ + ++E K +GK EK K ++++K+ ++ + +
Sbjct: 3 KKKKKKETEETEETEETEEEEEK-----EGKRKEKRKEKRKEKEKKKKTKETEKRKEKEE 57
Query: 237 VDKKPENDIVKSPQENLREPKRKRGRPPSIAPTAVDSNSQTLQPITLELRRRKISKGCEV 296
+KK + K +E RE + + + + + E RRRK
Sbjct: 58 EEKKRKRKRKKKKEEEEREEEEE------------EEEEEKEEEEKEEGRRRK------- 98
Query: 297 PLKRPRLDKNSSQEKSKNYSENTDK 321
K+ R K +EK K T K
Sbjct: 99 -KKKKRRRKEEEEEKKKKRRRKTKK 122
Score = 31.2 bits (69), Expect = 5.2
Identities = 15/61 (24%), Positives = 35/61 (57%)
Query: 512 RKRVSASSPTTKDKEKNKEKKFKEFVRVKPKKKKKKKKKTKPECPCSEEISDTSQEPSPP 571
+K+ + T++ E+ +E++ KE R + +K+K+K+K+ K + +E+ + +E
Sbjct: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62
Query: 572 K 572
K
Sbjct: 63 K 63
Score = 30.4 bits (67), Expect = 8.8
Identities = 19/73 (26%), Positives = 34/73 (46%), Gaps = 1/73 (1%)
Query: 480 EKSLEPEESPGKRHVQTRGPSASDKPSQETLTRKRVSASSPTTKDKEKNKEKKFKEFVRV 539
EK E EE KR + R ++ +E + ++ + K+KK +
Sbjct: 50 EKRKEKEEEEKKRK-RKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEE 108
Query: 540 KPKKKKKKKKKTK 552
+ +KKKK+++KTK
Sbjct: 109 EEEKKKKRRRKTK 121
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.130 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,188,995
Number of Sequences: 37866
Number of extensions: 2370590
Number of successful extensions: 14209
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 157
Number of HSP's successfully gapped in prelim test: 469
Number of HSP's that attempted gapping in prelim test: 9806
Number of HSP's gapped (non-prelim): 3432
length of query: 1012
length of database: 18,247,518
effective HSP length: 112
effective length of query: 900
effective length of database: 14,006,526
effective search space: 12605873400
effective search space used: 12605873400
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.