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Search of human proteins with 17402873
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|17402873 BRCA2 and CDKN1A-interacting protein isoform C
[Homo sapiens]
(292 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|17402873 BRCA2 and CDKN1A-interacting protein isoform C [Homo... 590 e-169
gi|7706581 BRCA2 and CDKN1A-interacting protein isoform BCCIPalp... 573 e-164
gi|17402871 BRCA2 and CDKN1A-interacting protein isoform BCCIPbe... 518 e-147
gi|158631177 homeodomain leucine zipper protein [Homo sapiens] 47 3e-05
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 45 6e-05
gi|21361639 DIPB protein [Homo sapiens] 45 1e-04
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 45 1e-04
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 45 1e-04
gi|17975763 myelin transcription factor 1 [Homo sapiens] 44 1e-04
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 44 1e-04
gi|55956788 nucleolin [Homo sapiens] 44 2e-04
gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo ... 44 2e-04
gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo ... 44 2e-04
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 44 2e-04
gi|51477718 TATA box binding protein-associated factor, RNA poly... 42 5e-04
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 42 6e-04
gi|13654270 LAS1-like [Homo sapiens] 42 8e-04
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 41 0.001
gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens] 41 0.001
gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens] 41 0.001
gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens] 41 0.001
gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens] 41 0.001
gi|210032580 SET domain containing 1B [Homo sapiens] 41 0.001
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] 40 0.002
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 40 0.002
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens] 40 0.002
gi|58331272 zinc finger, CCHC domain containing 6 [Homo sapiens] 40 0.002
gi|4503257 death-domain associated protein isoform a [Homo sapiens] 40 0.003
gi|215422388 death-domain associated protein isoform a [Homo sap... 40 0.003
gi|215422366 death-domain associated protein isoform b [Homo sap... 40 0.003
>gi|17402873 BRCA2 and CDKN1A-interacting protein isoform C [Homo
sapiens]
Length = 292
Score = 590 bits (1521), Expect = e-169
Identities = 292/292 (100%), Positives = 292/292 (100%)
Query: 1 MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE
Sbjct: 1 MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
Query: 61 FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD 120
FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD
Sbjct: 61 FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD 120
Query: 121 EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLL 180
EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLL
Sbjct: 121 EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLL 180
Query: 181 SERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSN 240
SERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSN
Sbjct: 181 SERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSN 240
Query: 241 KKKAALMFANAEEEFFYEEQGKPEVLGGPDTRRGLEPVPIQHNGWSVPPVLE 292
KKKAALMFANAEEEFFYEEQGKPEVLGGPDTRRGLEPVPIQHNGWSVPPVLE
Sbjct: 241 KKKAALMFANAEEEFFYEEQGKPEVLGGPDTRRGLEPVPIQHNGWSVPPVLE 292
>gi|7706581 BRCA2 and CDKN1A-interacting protein isoform BCCIPalpha
[Homo sapiens]
Length = 322
Score = 573 bits (1477), Expect = e-164
Identities = 285/286 (99%), Positives = 285/286 (99%)
Query: 1 MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE
Sbjct: 1 MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
Query: 61 FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD 120
FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD
Sbjct: 61 FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD 120
Query: 121 EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLL 180
EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLL
Sbjct: 121 EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLL 180
Query: 181 SERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSN 240
SERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSN
Sbjct: 181 SERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSN 240
Query: 241 KKKAALMFANAEEEFFYEEQGKPEVLGGPDTRRGLEPVPIQHNGWS 286
KKKAALMFANAEEEFFYEEQGKPEVLGGPDTRRGLEPVPIQHNG S
Sbjct: 241 KKKAALMFANAEEEFFYEEQGKPEVLGGPDTRRGLEPVPIQHNGGS 286
>gi|17402871 BRCA2 and CDKN1A-interacting protein isoform BCCIPbeta
[Homo sapiens]
Length = 314
Score = 518 bits (1333), Expect = e-147
Identities = 258/259 (99%), Positives = 259/259 (100%)
Query: 1 MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE
Sbjct: 1 MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
Query: 61 FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD 120
FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD
Sbjct: 61 FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD 120
Query: 121 EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLL 180
EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLL
Sbjct: 121 EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLL 180
Query: 181 SERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSN 240
SERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSN
Sbjct: 181 SERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSN 240
Query: 241 KKKAALMFANAEEEFFYEE 259
KKKAALMFANAEEEFFYE+
Sbjct: 241 KKKAALMFANAEEEFFYEK 259
>gi|158631177 homeodomain leucine zipper protein [Homo sapiens]
Length = 550
Score = 46.6 bits (109), Expect = 3e-05
Identities = 21/50 (42%), Positives = 36/50 (72%)
Query: 11 ESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
+S +PQP + V DEEEE+E E EDD++ ++E++E+D+ D++V I+
Sbjct: 500 DSRLPQPAEVVVCLDEEEEEEEEELPEDDEEEEEEEEEDDDDDDDDVIIQ 549
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 45.4 bits (106), Expect = 6e-05
Identities = 24/55 (43%), Positives = 36/55 (65%), Gaps = 6/55 (10%)
Query: 15 PQPPDPPVQ------RDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEA 63
PQ P PVQ +EEEE+E E E+E+D++ ++E++EE+E +EE E EA
Sbjct: 718 PQVPLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEA 772
Score = 40.4 bits (93), Expect = 0.002
Identities = 18/49 (36%), Positives = 32/49 (65%)
Query: 14 VPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62
VP P P +EEE+E E ++E++++ ++E++EE+E +EE E E
Sbjct: 720 VPLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEE 768
Score = 28.9 bits (63), Expect = 5.6
Identities = 12/33 (36%), Positives = 23/33 (69%)
Query: 25 DEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEV 57
+EEEE+E E E+E++++ ++E++ V EV
Sbjct: 749 EEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEV 781
>gi|21361639 DIPB protein [Homo sapiens]
Length = 344
Score = 44.7 bits (104), Expect = 1e-04
Identities = 22/68 (32%), Positives = 37/68 (54%), Gaps = 5/68 (7%)
Query: 6 KRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYS 65
+ R +ES + + + + EEE E E E ED+ D + E+D E+E+ DE+ E+ +
Sbjct: 87 QEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQ-----ESEA 141
Query: 66 LSDNDYDG 73
DN +G
Sbjct: 142 EEDNQEEG 149
Score = 31.2 bits (69), Expect = 1.1
Identities = 13/50 (26%), Positives = 28/50 (56%)
Query: 23 QRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYD 72
+ E+E E ED +++ D+++ E +E EE E E + +++++D
Sbjct: 115 EESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFD 164
Score = 30.4 bits (67), Expect = 1.9
Identities = 18/62 (29%), Positives = 30/62 (48%), Gaps = 3/62 (4%)
Query: 11 ESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDND 70
ES + + + EE+ E E EDE + +++++ EE E E E EA S D +
Sbjct: 110 ESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGE---SEAEGETEAESEFDPE 166
Query: 71 YD 72
+
Sbjct: 167 IE 168
Score = 30.0 bits (66), Expect = 2.5
Identities = 15/44 (34%), Positives = 29/44 (65%), Gaps = 1/44 (2%)
Query: 27 EEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDND 70
E+E+E+E+E ++ +S++E + E+E EE + E E+ S+ D
Sbjct: 86 EQEREIESEAGEESESEEESESEEESETEEES-EDESDEESEED 128
Score = 28.1 bits (61), Expect = 9.5
Identities = 18/55 (32%), Positives = 28/55 (50%), Gaps = 1/55 (1%)
Query: 17 PPDPPVQRDEEEEKEVENEDEDDDDSDKEKD-EEDEVIDEEVNIEFEAYSLSDND 70
P D EE E +VE E E + ++ +E + EE+ +EE E E+ SD +
Sbjct: 70 PADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEE 124
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 44.7 bits (104), Expect = 1e-04
Identities = 21/70 (30%), Positives = 41/70 (58%), Gaps = 2/70 (2%)
Query: 3 SRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62
+ ++ VE V + D V+ D EE++EV+ + E++++ ++E++EE+E +EE +
Sbjct: 198 TENEEEGVEEDVEE--DEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDER 255
Query: 63 AYSLSDNDYD 72
NDYD
Sbjct: 256 DQKEEGNDYD 265
Score = 37.0 bits (84), Expect = 0.021
Identities = 16/47 (34%), Positives = 30/47 (63%)
Query: 19 DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYS 65
D V D EEE+E E E+E++++ ++E+ E+DE +E +++ S
Sbjct: 222 DEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRS 268
Score = 33.1 bits (74), Expect = 0.30
Identities = 14/42 (33%), Positives = 26/42 (61%)
Query: 19 DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
D + +EEEE+E E E+E+++ E+D+++E D + E
Sbjct: 228 DGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSE 269
Score = 30.4 bits (67), Expect = 1.9
Identities = 15/46 (32%), Positives = 25/46 (54%)
Query: 23 QRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSD 68
+ +EEEE+E E E E D+ KE+ + + E + E+ S +D
Sbjct: 237 EEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTD 282
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 44.7 bits (104), Expect = 1e-04
Identities = 21/70 (30%), Positives = 41/70 (58%), Gaps = 2/70 (2%)
Query: 3 SRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62
+ ++ VE V + D V+ D EE++EV+ + E++++ ++E++EE+E +EE +
Sbjct: 198 TENEEEGVEEDVEE--DEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDER 255
Query: 63 AYSLSDNDYD 72
NDYD
Sbjct: 256 DQKEEGNDYD 265
Score = 37.0 bits (84), Expect = 0.021
Identities = 16/47 (34%), Positives = 30/47 (63%)
Query: 19 DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYS 65
D V D EEE+E E E+E++++ ++E+ E+DE +E +++ S
Sbjct: 222 DEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRS 268
Score = 33.1 bits (74), Expect = 0.30
Identities = 14/42 (33%), Positives = 26/42 (61%)
Query: 19 DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
D + +EEEE+E E E+E+++ E+D+++E D + E
Sbjct: 228 DGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSE 269
Score = 30.4 bits (67), Expect = 1.9
Identities = 15/46 (32%), Positives = 25/46 (54%)
Query: 23 QRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSD 68
+ +EEEE+E E E E D+ KE+ + + E + E+ S +D
Sbjct: 237 EEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTD 282
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 44.3 bits (103), Expect = 1e-04
Identities = 39/165 (23%), Positives = 72/165 (43%), Gaps = 9/165 (5%)
Query: 5 SKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEA- 63
SK++ + S + + + +EEEE E E E+E++++ ++E++EE+E +EE E EA
Sbjct: 249 SKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAA 308
Query: 64 ---YSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD 120
D + +K + L+ P + + + + K D + D
Sbjct: 309 PDVIFQEDTSHTSAQKAPE---LRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTD 365
Query: 121 EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQL 165
E E+ ++ NL + Q + E V CE C + QL
Sbjct: 366 ESEMQDMMTRGNLGLLE--QAIALKAEQVRTVCEPGCPPAEQSQL 408
Score = 32.3 bits (72), Expect = 0.51
Identities = 13/48 (27%), Positives = 29/48 (60%)
Query: 15 PQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62
PQ + + ++K + + +E+D++ ++E++EE+E +EE E E
Sbjct: 237 PQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEE 284
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 44.3 bits (103), Expect = 1e-04
Identities = 39/138 (28%), Positives = 65/138 (47%), Gaps = 17/138 (12%)
Query: 11 ESGVPQPPDPPVQRDEEEEKEVENEDEDDD--DSDKEKDEEDEVIDEEVNIEFEAYSLS- 67
E G D R+EEEE E E+ED+D+D D + E++EE+E +EE E E + ++
Sbjct: 116 EPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNC 175
Query: 68 ------------DNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDS 115
DN+ D +L K+ +N ++ + + S + ++ S
Sbjct: 176 HNTRIMQDTEKDDNNNDEYDN-YDELVAKSLLNLGKIAEDAAYRARTESEM-NSNTSNSL 233
Query: 116 NDDMDEDEVFGFISLLNL 133
DD D++E G S L+L
Sbjct: 234 EDDSDKNENLGRKSELSL 251
Score = 40.8 bits (94), Expect = 0.001
Identities = 35/129 (27%), Positives = 61/129 (47%), Gaps = 4/129 (3%)
Query: 8 RAVESGVPQPPDPPVQRDEEEEKEVENED-EDDDDSDKEKDEEDEVIDEEVNIEFEAYSL 66
+A S V + D D +E++E E E+ +D+D ++DEEDE D E E E
Sbjct: 81 KADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEED- 139
Query: 67 SDNDYDG--IKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMDEDEV 124
D+D DG ++ ++ + E + H +++ T+ +++ND+ D +
Sbjct: 140 EDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDE 199
Query: 125 FGFISLLNL 133
SLLNL
Sbjct: 200 LVAKSLLNL 208
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 43.5 bits (101), Expect = 2e-04
Identities = 17/35 (48%), Positives = 28/35 (80%)
Query: 22 VQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEE 56
V DE+EE++ E+ED+DDD+ D++ D+ED+ +EE
Sbjct: 232 VAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEE 266
Score = 40.8 bits (94), Expect = 0.001
Identities = 17/37 (45%), Positives = 28/37 (75%)
Query: 26 EEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62
E+E++E ++EDEDDDD + ++D++DE +EE E E
Sbjct: 234 EDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEE 270
Score = 39.7 bits (91), Expect = 0.003
Identities = 38/137 (27%), Positives = 58/137 (42%), Gaps = 24/137 (17%)
Query: 2 ASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDE---------------DDDDSDKEK 46
A K E + D + +E++E E E+EDE +D+D + ++
Sbjct: 134 AKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDE 193
Query: 47 DEEDEVIDEEVNIEFEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVI 106
D+ED+ DEE + E EA + KK + + +KA N AE D
Sbjct: 194 DDEDDDDDEEDDSEEEAMETTPAKG---KKAAKVVPVKAK-NVAEDED-----EEEDDED 244
Query: 107 KQTDVSEDSNDDMDEDE 123
+ D ED DD DED+
Sbjct: 245 EDDDDDEDDEDDDDEDD 261
Score = 38.1 bits (87), Expect = 0.009
Identities = 17/43 (39%), Positives = 27/43 (62%)
Query: 20 PPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62
P ++ E+++ E +DED+DD D E DE+D+ D+E E E
Sbjct: 226 PVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEE 268
Score = 37.7 bits (86), Expect = 0.012
Identities = 14/39 (35%), Positives = 28/39 (71%)
Query: 19 DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEV 57
D + D+E+E + ++ED++DDD + +++EE+E +E V
Sbjct: 235 DEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPV 273
Score = 36.2 bits (82), Expect = 0.035
Identities = 33/149 (22%), Positives = 52/149 (34%), Gaps = 32/149 (21%)
Query: 18 PDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKKL 77
P + + +KE +E+EDDD + E+D+EDE D D D I+
Sbjct: 130 PAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDE----------------DEDEDEIEPA 173
Query: 78 LQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMDEDEVFGFISLLNLTERK 137
+ AP + E + ED DD D++E + T K
Sbjct: 174 AMKAAAAAPASEDE----------------DDEDDEDDEDDDDDEEDDSEEEAMETTPAK 217
Query: 138 GTQCVEQIQELVLRFCEKNCEKSMVEQLD 166
G + + + E E+ E D
Sbjct: 218 GKKAAKVVPVKAKNVAEDEDEEEDDEDED 246
Score = 32.7 bits (73), Expect = 0.39
Identities = 12/44 (27%), Positives = 28/44 (63%)
Query: 6 KRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEE 49
K + V + D + D+++E + +++DEDD++ ++E++EE
Sbjct: 228 KAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEE 271
Score = 30.8 bits (68), Expect = 1.5
Identities = 11/42 (26%), Positives = 28/42 (66%)
Query: 35 EDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKK 76
EDED+++ D+++D++D+ DE+ + E + + + + +K+
Sbjct: 234 EDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKE 275
Score = 29.6 bits (65), Expect = 3.3
Identities = 12/26 (46%), Positives = 18/26 (69%)
Query: 20 PPVQRDEEEEKEVENEDEDDDDSDKE 45
PP + +E+ E E +EDE+DD S +E
Sbjct: 20 PPKEVEEDSEDEEMSEDEEDDSSGEE 45
Score = 28.1 bits (61), Expect = 9.5
Identities = 19/47 (40%), Positives = 24/47 (51%), Gaps = 10/47 (21%)
Query: 13 GVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNI 59
G P+ PP KEVE ED +D + +DEED+ EEV I
Sbjct: 12 GDPKKMAPP-------PKEVE---EDSEDEEMSEDEEDDSSGEEVVI 48
>gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo
sapiens]
Length = 5033
Score = 43.5 bits (101), Expect = 2e-04
Identities = 22/69 (31%), Positives = 41/69 (59%)
Query: 19 DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKKLL 78
+P V +EEEE++ E E E++D+ +KE+DEE+ ++E + E + +G+++ L
Sbjct: 1867 EPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEKEEGLEEGL 1926
Query: 79 QQLFLKAPV 87
Q+ L V
Sbjct: 1927 LQMKLPESV 1935
Score = 30.0 bits (66), Expect = 2.5
Identities = 14/49 (28%), Positives = 27/49 (55%)
Query: 8 RAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEE 56
+ +E V + +EE E+E E E E+D++ ++ E++E +EE
Sbjct: 1864 KMIEPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEE 1912
>gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo
sapiens]
Length = 5038
Score = 43.5 bits (101), Expect = 2e-04
Identities = 22/69 (31%), Positives = 41/69 (59%)
Query: 19 DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKKLL 78
+P V +EEEE++ E E E++D+ +KE+DEE+ ++E + E + +G+++ L
Sbjct: 1867 EPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEKEEGLEEGL 1926
Query: 79 QQLFLKAPV 87
Q+ L V
Sbjct: 1927 LQMKLPESV 1935
Score = 30.0 bits (66), Expect = 2.5
Identities = 14/49 (28%), Positives = 27/49 (55%)
Query: 8 RAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEE 56
+ +E V + +EE E+E E E E+D++ ++ E++E +EE
Sbjct: 1864 KMIEPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEE 1912
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 43.5 bits (101), Expect = 2e-04
Identities = 20/54 (37%), Positives = 35/54 (64%)
Query: 23 QRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKK 76
+ +EEEE E E E+E++++ D+E++EE+E +EE NI+ L+ IK+
Sbjct: 1070 EEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKR 1123
Score = 37.4 bits (85), Expect = 0.016
Identities = 14/34 (41%), Positives = 27/34 (79%)
Query: 23 QRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEE 56
+ EEE+E E+E+E++++ ++E+DEE+E +EE
Sbjct: 1066 KESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEE 1099
Score = 34.7 bits (78), Expect = 0.10
Identities = 20/66 (30%), Positives = 35/66 (53%)
Query: 4 RSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEA 63
+SK + + S +P + E KE E+E+++D ++E++EE+E DEE E E
Sbjct: 1040 QSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEE 1099
Query: 64 YSLSDN 69
+N
Sbjct: 1100 EEEEEN 1105
Score = 33.5 bits (75), Expect = 0.23
Identities = 13/48 (27%), Positives = 31/48 (64%)
Query: 22 VQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDN 69
++ +E +E E E++++++ ++E++EEDE +EE E E ++ +
Sbjct: 1062 LELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSS 1109
Score = 33.1 bits (74), Expect = 0.30
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 5/92 (5%)
Query: 14 VPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDG 73
V + PD + E+EE E+ E ED D ++EE+E + N + +A D+ +
Sbjct: 1378 VEKDPDG-AKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMES 1436
Query: 74 I----KKLLQQLFLKAPVNTAELTDLLIQQNH 101
++L ++ F + N DL +Q H
Sbjct: 1437 AEVEKEELPRESFKEVLENQETFLDLNVQPGH 1468
Score = 32.0 bits (71), Expect = 0.66
Identities = 25/120 (20%), Positives = 53/120 (44%), Gaps = 10/120 (8%)
Query: 4 RSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEA 63
+ + R E+ P P+ E++ E+E++++ ++E++EE+E +EE E
Sbjct: 1321 QEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVE- 1379
Query: 64 YSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMDEDE 123
D DG K ++ P + E D +H + + S + + D D+++
Sbjct: 1380 -----KDPDGAKSQEKE----EPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDED 1430
Score = 30.4 bits (67), Expect = 1.9
Identities = 15/73 (20%), Positives = 38/73 (52%)
Query: 3 SRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62
S +K ++ + P PV + + E+ E ++++ +++++EE+E +EE + E E
Sbjct: 1035 SPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEE 1094
Query: 63 AYSLSDNDYDGIK 75
+ + + I+
Sbjct: 1095 EEEEEEEEEENIQ 1107
>gi|51477718 TATA box binding protein-associated factor, RNA
polymerase II, Q [Homo sapiens]
Length = 462
Score = 42.4 bits (98), Expect = 5e-04
Identities = 29/115 (25%), Positives = 56/115 (48%), Gaps = 15/115 (13%)
Query: 19 DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEF---EAYSLSDNDYDGIK 75
D D+E+E E E+EDED+D ++E+D +E ++ ++ EF Y ++ +
Sbjct: 333 DDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLERQLQAEFIESGQYRANEGTSSIVM 392
Query: 76 KLLQQLFLKAP-----VNTAELTDLLIQ-------QNHIGSVIKQTDVSEDSNDD 118
++ +Q+ K N A+ LI +NH SV++Q ++ E ++
Sbjct: 393 EIQKQIEKKEKKLHKIQNKAQRQKDLIMKVENLTLKNHFQSVLEQLELQEKQKNE 447
Score = 37.4 bits (85), Expect = 0.016
Identities = 39/149 (26%), Positives = 75/149 (50%), Gaps = 13/149 (8%)
Query: 24 RDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKKLLQQLFL 83
R+ + N+D++D+D + E ++EDE DE+ E E D + +++ LQ F+
Sbjct: 322 REMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEE-----DCSEEYLERQLQAEFI 376
Query: 84 KAPVNTA-ELTDLLIQQNHIGSVIKQTDVSEDSNDDMDEDEVFGFISLLNLTERKGTQCV 142
++ A E T ++ + K+ + + N + ++ + + NLT + Q V
Sbjct: 377 ESGQYRANEGTSSIVMEIQKQIEKKEKKLHKIQNKAQRQKDL--IMKVENLTLKNHFQSV 434
Query: 143 EQIQELVLRFCEKNCEK--SMVEQLDKFL 169
+++L L+ +KN EK S+ EQL +FL
Sbjct: 435 --LEQLELQEKQKN-EKLISLQEQLQRFL 460
>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member B [Homo sapiens]
Length = 251
Score = 42.0 bits (97), Expect = 6e-04
Identities = 24/59 (40%), Positives = 34/59 (57%), Gaps = 11/59 (18%)
Query: 25 DEEEEKEVENEDEDDDDSD------KEKDEEDEVI-----DEEVNIEFEAYSLSDNDYD 72
DEEEE E ++ED+DD D E+D+EDE + D+EV+ E E + L + D D
Sbjct: 166 DEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDED 224
Score = 33.5 bits (75), Expect = 0.23
Identities = 21/56 (37%), Positives = 31/56 (55%), Gaps = 4/56 (7%)
Query: 11 ESGVPQPPDPPVQRDEEEEKEVENEDED---DDDSDKEKDEEDEV-IDEEVNIEFE 62
E G + + +EEE E ++EDED D+D D+ +EE+E +DEE E E
Sbjct: 172 EEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDE 227
Score = 33.1 bits (74), Expect = 0.30
Identities = 14/36 (38%), Positives = 28/36 (77%), Gaps = 4/36 (11%)
Query: 25 DEEEEKEVENEDEDDDDSDKEK----DEEDEVIDEE 56
+++E+++VE +++DD+ S++E+ DEEDE DE+
Sbjct: 193 EDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDED 228
Score = 31.2 bits (69), Expect = 1.1
Identities = 19/55 (34%), Positives = 29/55 (52%), Gaps = 4/55 (7%)
Query: 19 DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDG 73
D + E V+ E+ED++ D E+DE+DE +EE EF+ D D +G
Sbjct: 152 DQEAPDSDAEVDGVDEEEEDEEGED-EEDEDDEDGEEE---EFDEEDDEDEDVEG 202
Score = 30.8 bits (68), Expect = 1.5
Identities = 15/37 (40%), Positives = 26/37 (70%), Gaps = 5/37 (13%)
Query: 19 DPPVQRDEEEEKEVENEDE----DDDDSDKEKDEEDE 51
D V+ DE+++ EV E+E D++D D+++DEE+E
Sbjct: 197 DEDVEGDEDDD-EVSEEEEEFGLDEEDEDEDEDEEEE 232
>gi|13654270 LAS1-like [Homo sapiens]
Length = 734
Score = 41.6 bits (96), Expect = 8e-04
Identities = 21/49 (42%), Positives = 33/49 (67%), Gaps = 5/49 (10%)
Query: 22 VQRDEEEEKEV-----ENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYS 65
V+ +E+EEKEV E E+E+DD ++E+DE+DE +EE +E +S
Sbjct: 564 VKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRMEVGPFS 612
Score = 33.9 bits (76), Expect = 0.17
Identities = 14/33 (42%), Positives = 21/33 (63%)
Query: 20 PPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEV 52
P +EEE + E E+ED+DD D E+++ EV
Sbjct: 576 PDQVEEEEENDDQEEEEEDEDDEDDEEEDRMEV 608
Score = 33.1 bits (74), Expect = 0.30
Identities = 12/28 (42%), Positives = 20/28 (71%)
Query: 18 PDPPVQRDEEEEKEVENEDEDDDDSDKE 45
PD + +E +++E E EDEDD+D ++E
Sbjct: 576 PDQVEEEEENDDQEEEEEDEDDEDDEEE 603
Score = 30.8 bits (68), Expect = 1.5
Identities = 10/31 (32%), Positives = 21/31 (67%)
Query: 14 VPQPPDPPVQRDEEEEKEVENEDEDDDDSDK 44
+P + + D++EE+E + +DEDD++ D+
Sbjct: 575 LPDQVEEEEENDDQEEEEEDEDDEDDEEEDR 605
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 41.2 bits (95), Expect = 0.001
Identities = 17/44 (38%), Positives = 31/44 (70%)
Query: 19 DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62
D + +EEEE+E E E+E+++D ++E+++E+E +EE E E
Sbjct: 887 DEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEE 930
Score = 38.1 bits (87), Expect = 0.009
Identities = 15/38 (39%), Positives = 28/38 (73%)
Query: 23 QRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
+ +EEEE++ E E+ED+++ +E++EE+E +EE E
Sbjct: 901 EEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEE 938
Score = 37.4 bits (85), Expect = 0.016
Identities = 19/54 (35%), Positives = 33/54 (61%), Gaps = 1/54 (1%)
Query: 10 VESGVPQPPDPPVQRDEEEEKEVENED-EDDDDSDKEKDEEDEVIDEEVNIEFE 62
+ S + + + +EEEE+E E ED E++++ ++E EE+E +EE EFE
Sbjct: 883 INSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFE 936
Score = 36.6 bits (83), Expect = 0.027
Identities = 16/51 (31%), Positives = 32/51 (62%)
Query: 23 QRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDG 73
+ +EEEE+E E E+E++++ +E++E++E EE E E + + +G
Sbjct: 890 EEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEG 940
Score = 35.4 bits (80), Expect = 0.060
Identities = 15/53 (28%), Positives = 30/53 (56%)
Query: 10 VESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62
V G P PP ++ + + DE++++ ++E++EE+E +EE + E E
Sbjct: 861 VPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEE 913
Score = 34.7 bits (78), Expect = 0.10
Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 1/79 (1%)
Query: 8 RAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLS 67
R ES PP + +E E+E +D SDK + + +EE+ E EA +L
Sbjct: 1039 REGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQ 1098
Query: 68 DNDYDGIKKLLQQLFLKAP 86
+ + D +L F+ P
Sbjct: 1099 EKEQDDTAAMLAD-FIDCP 1116
Score = 34.3 bits (77), Expect = 0.13
Identities = 15/36 (41%), Positives = 28/36 (77%), Gaps = 1/36 (2%)
Query: 23 QRDEEEEKEVENE-DEDDDDSDKEKDEEDEVIDEEV 57
+ +EEEE+E E E +E++ + ++E++EEDE +EE+
Sbjct: 922 EEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEEL 957
Score = 33.1 bits (74), Expect = 0.30
Identities = 16/37 (43%), Positives = 24/37 (64%)
Query: 26 EEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62
EEEE+E E +E+ ++ + E +EE+E DEE E E
Sbjct: 922 EEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELE 958
Score = 32.7 bits (73), Expect = 0.39
Identities = 13/40 (32%), Positives = 28/40 (70%)
Query: 23 QRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62
+ +E+EE+ E E+E++++ ++E +EE+ ++EE E E
Sbjct: 912 EEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDE 951
Score = 32.0 bits (71), Expect = 0.66
Identities = 13/36 (36%), Positives = 26/36 (72%)
Query: 25 DEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
+EEEE+E E+ ++++ + E++EE+E +EE +E
Sbjct: 923 EEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELE 958
Score = 28.5 bits (62), Expect = 7.3
Identities = 11/55 (20%), Positives = 34/55 (61%)
Query: 23 QRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKKL 77
+ ++ EE+E + E+ +++ ++E++ E+E +EE +E E + + + ++++
Sbjct: 906 EEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEV 960
>gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens]
Length = 619
Score = 41.2 bits (95), Expect = 0.001
Identities = 17/42 (40%), Positives = 30/42 (71%)
Query: 19 DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
+P EE++KE +++DEDDDD + E++EE+E D++ + E
Sbjct: 128 EPGGDGGEEDDKEDDDDDEDDDDEEDEEEEEEEEEDDDDDTE 169
Score = 38.1 bits (87), Expect = 0.009
Identities = 16/45 (35%), Positives = 31/45 (68%)
Query: 25 DEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDN 69
D EE + E++D+D+DD D+E +EE+E +E+ + + E ++ +N
Sbjct: 132 DGGEEDDKEDDDDDEDDDDEEDEEEEEEEEEDDDDDTEDFADQEN 176
Score = 33.9 bits (76), Expect = 0.17
Identities = 13/32 (40%), Positives = 23/32 (71%)
Query: 25 DEEEEKEVENEDEDDDDSDKEKDEEDEVIDEE 56
DEE+E+E E E+EDDDD ++ +++ + D +
Sbjct: 150 DEEDEEEEEEEEEDDDDDTEDFADQENLPDPQ 181
Score = 33.5 bits (75), Expect = 0.23
Identities = 14/35 (40%), Positives = 23/35 (65%)
Query: 25 DEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNI 59
D+EE++E E E+E+DDD D E + E + + +I
Sbjct: 149 DDEEDEEEEEEEEEDDDDDTEDFADQENLPDPQDI 183
Score = 32.7 bits (73), Expect = 0.39
Identities = 12/41 (29%), Positives = 27/41 (65%)
Query: 30 KEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDND 70
+E + ED+DDD+ D ++++E+E +EE + + + +D +
Sbjct: 135 EEDDKEDDDDDEDDDDEEDEEEEEEEEEDDDDDTEDFADQE 175
Score = 28.1 bits (61), Expect = 9.5
Identities = 14/41 (34%), Positives = 23/41 (56%)
Query: 32 VENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYD 72
+E + ++ DKE D++DE D+E + E E D+D D
Sbjct: 127 MEPGGDGGEEDDKEDDDDDEDDDDEEDEEEEEEEEEDDDDD 167
>gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens]
Length = 1087
Score = 40.8 bits (94), Expect = 0.001
Identities = 26/104 (25%), Positives = 53/104 (50%), Gaps = 6/104 (5%)
Query: 2 ASRSKRRAVESGVPQPPDPPVQRDEEEEKEV-ENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
A + R +G + +P + +EEEE+E E E+E+DDD +K I +E +++
Sbjct: 24 AEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVD 83
Query: 61 FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGS 104
E Y D DG + +L+ K + + + ++++ ++ G+
Sbjct: 84 DE-YEDEDQWEDGAEDILE----KEEIEASNIDNVVLDEDRSGA 122
Score = 28.1 bits (61), Expect = 9.5
Identities = 16/43 (37%), Positives = 22/43 (51%)
Query: 28 EEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDND 70
EE EV+ E S+KE++ EDE +EE E D+D
Sbjct: 22 EEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDD 64
>gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens]
Length = 1087
Score = 40.8 bits (94), Expect = 0.001
Identities = 26/104 (25%), Positives = 53/104 (50%), Gaps = 6/104 (5%)
Query: 2 ASRSKRRAVESGVPQPPDPPVQRDEEEEKEV-ENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
A + R +G + +P + +EEEE+E E E+E+DDD +K I +E +++
Sbjct: 24 AEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVD 83
Query: 61 FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGS 104
E Y D DG + +L+ K + + + ++++ ++ G+
Sbjct: 84 DE-YEDEDQWEDGAEDILE----KEEIEASNIDNVVLDEDRSGA 122
Score = 28.1 bits (61), Expect = 9.5
Identities = 16/43 (37%), Positives = 22/43 (51%)
Query: 28 EEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDND 70
EE EV+ E S+KE++ EDE +EE E D+D
Sbjct: 22 EEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDD 64
>gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens]
Length = 1087
Score = 40.8 bits (94), Expect = 0.001
Identities = 26/104 (25%), Positives = 53/104 (50%), Gaps = 6/104 (5%)
Query: 2 ASRSKRRAVESGVPQPPDPPVQRDEEEEKEV-ENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
A + R +G + +P + +EEEE+E E E+E+DDD +K I +E +++
Sbjct: 24 AEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVD 83
Query: 61 FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGS 104
E Y D DG + +L+ K + + + ++++ ++ G+
Sbjct: 84 DE-YEDEDQWEDGAEDILE----KEEIEASNIDNVVLDEDRSGA 122
Score = 28.1 bits (61), Expect = 9.5
Identities = 16/43 (37%), Positives = 22/43 (51%)
Query: 28 EEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDND 70
EE EV+ E S+KE++ EDE +EE E D+D
Sbjct: 22 EEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDD 64
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 40.8 bits (94), Expect = 0.001
Identities = 21/48 (43%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
Query: 25 DEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYD 72
+EEEE E E E+EDDDD D + +E E DE+ + EA + D D
Sbjct: 1049 EEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALS-EASEKDEGDSD 1095
Score = 29.6 bits (65), Expect = 3.3
Identities = 10/34 (29%), Positives = 22/34 (64%)
Query: 16 QPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEE 49
+PPD D++ + + DE+D++S++E+D +
Sbjct: 968 EPPDTTSSGDQKRLRPSTSVDEEDEESERERDRD 1001
Score = 29.3 bits (64), Expect = 4.3
Identities = 20/49 (40%), Positives = 29/49 (59%), Gaps = 4/49 (8%)
Query: 25 DEEEEKEVENEDEDDDDSD-KEKDEEDEVIDEEVNI---EFEAYSLSDN 69
D ++ E EN+DED S+ EKDE D +E V+I + EA S S++
Sbjct: 1067 DSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSES 1115
>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
Length = 4374
Score = 40.4 bits (93), Expect = 0.002
Identities = 22/63 (34%), Positives = 35/63 (55%), Gaps = 2/63 (3%)
Query: 18 PDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKKL 77
P+ + +EE+ NEDEDD ++E++EEDE D+E + E D+D DG +
Sbjct: 2409 PEDEEEHTQEEDSSGSNEDEDDSQDEEEEEEEDEEDDQEDDEGEEGD--EDDDDDGSEME 2466
Query: 78 LQQ 80
L +
Sbjct: 2467 LDE 2469
Score = 37.0 bits (84), Expect = 0.021
Identities = 19/54 (35%), Positives = 31/54 (57%), Gaps = 2/54 (3%)
Query: 19 DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYD 72
DP + + +E++ +ED+DDS E++EE+E DEE + E + D D D
Sbjct: 2408 DPEDEEEHTQEEDSSGSNEDEDDSQDEEEEEEE--DEEDDQEDDEGEEGDEDDD 2459
Score = 36.2 bits (82), Expect = 0.035
Identities = 14/50 (28%), Positives = 32/50 (64%)
Query: 12 SGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEF 61
SG + D +EEEE++ E++ EDD+ + ++D++D+ + E++ ++
Sbjct: 2422 SGSNEDEDDSQDEEEEEEEDEEDDQEDDEGEEGDEDDDDDGSEMELDEDY 2471
Score = 35.4 bits (80), Expect = 0.060
Identities = 17/56 (30%), Positives = 32/56 (57%), Gaps = 1/56 (1%)
Query: 16 QPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDY 71
Q D ++E++ + E E+E++D+ D ++D+E E DE+ + + L D DY
Sbjct: 2417 QEEDSSGSNEDEDDSQDEEEEEEEDEEDDQEDDEGEEGDEDDDDDGSEMEL-DEDY 2471
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 40.4 bits (93), Expect = 0.002
Identities = 18/49 (36%), Positives = 33/49 (67%)
Query: 25 DEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDG 73
D K+ E+ +ED+++ D+E+DEED+ DE + + E+ S S++D +G
Sbjct: 597 DIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEG 645
Score = 38.9 bits (89), Expect = 0.005
Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 8/76 (10%)
Query: 8 RAVESGVPQPPDPPVQRDEEEEKEVENEDEDD-----DDSDKEKD---EEDEVIDEEVNI 59
R +S +P D ++EEE + E ++EDD DDS E D E D EE +
Sbjct: 592 RGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDD 651
Query: 60 EFEAYSLSDNDYDGIK 75
+ + SD+D +G K
Sbjct: 652 DDKDQDESDSDTEGEK 667
Score = 32.7 bits (73), Expect = 0.39
Identities = 19/56 (33%), Positives = 30/56 (53%), Gaps = 5/56 (8%)
Query: 4 RSKRRAVESGVPQPP---DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEE 56
R ++ G Q P P ++ + + + +D+DDDDSD + DE+DE DEE
Sbjct: 1266 RDTSGGIDLGEEQHPLGTPTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDE--DEE 1319
Score = 31.6 bits (70), Expect = 0.86
Identities = 19/63 (30%), Positives = 31/63 (49%), Gaps = 6/63 (9%)
Query: 13 GVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYD 72
G+ ++ DEEEE + E+ +DDDSD E + + + N + + +SD D
Sbjct: 259 GISSSDSDDLEEDEEEEDQ-SIEESEDDDSDSESEAQ-----HKSNNQVLLHGISDPKAD 312
Query: 73 GIK 75
G K
Sbjct: 313 GQK 315
Score = 28.5 bits (62), Expect = 7.3
Identities = 13/44 (29%), Positives = 25/44 (56%), Gaps = 2/44 (4%)
Query: 13 GVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEE 56
G P P +R + + + +++D+DD D ++D+EDE E+
Sbjct: 1282 GTPTPGRK--RRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKED 1323
Score = 28.1 bits (61), Expect = 9.5
Identities = 17/56 (30%), Positives = 29/56 (51%), Gaps = 3/56 (5%)
Query: 19 DPPVQRDEEEEKEVENEDEDDDDSD--KEKDEEDEVID-EEVNIEFEAYSLSDNDY 71
D Q DE++E E + ED+ +D +++DE D+ EE+ + E S + Y
Sbjct: 1306 DSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAASVEELEKQIEKLSKQQSQY 1361
>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
Length = 1390
Score = 40.0 bits (92), Expect = 0.002
Identities = 16/33 (48%), Positives = 25/33 (75%)
Query: 26 EEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVN 58
E+E+ E +++D+DDDD D ++D+EDE EE N
Sbjct: 258 EDEDDEDDDDDDDDDDDDDDEDDEDEEDGEEEN 290
Score = 37.7 bits (86), Expect = 0.012
Identities = 14/32 (43%), Positives = 24/32 (75%)
Query: 25 DEEEEKEVENEDEDDDDSDKEKDEEDEVIDEE 56
D+E E + E+ED++DDD D + D++D+ D+E
Sbjct: 250 DQEHEDDGEDEDDEDDDDDDDDDDDDDDEDDE 281
Score = 37.4 bits (85), Expect = 0.016
Identities = 14/34 (41%), Positives = 24/34 (70%)
Query: 23 QRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEE 56
+ E++E E + EDEDD+D D + D++D+ DE+
Sbjct: 246 EEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDED 279
Score = 37.0 bits (84), Expect = 0.021
Identities = 15/46 (32%), Positives = 28/46 (60%)
Query: 11 ESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEE 56
E V + Q E++ ++ ++ED+DDDD D + D++++ DEE
Sbjct: 239 EGSVESSEEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDEDDEDEE 284
Score = 37.0 bits (84), Expect = 0.021
Identities = 13/32 (40%), Positives = 26/32 (81%)
Query: 25 DEEEEKEVENEDEDDDDSDKEKDEEDEVIDEE 56
++E++++ +++D+DDDD D E DE++E +EE
Sbjct: 258 EDEDDEDDDDDDDDDDDDDDEDDEDEEDGEEE 289
Score = 35.8 bits (81), Expect = 0.046
Identities = 15/52 (28%), Positives = 32/52 (61%)
Query: 11 ESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62
+ G + + ++ E++ E E++++DDDD D + D++DE ++E + E E
Sbjct: 238 QEGSVESSEEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDEDDEDEEDGEEE 289
Score = 35.0 bits (79), Expect = 0.078
Identities = 15/45 (33%), Positives = 29/45 (64%)
Query: 25 DEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDN 69
+E E++E E++ ED+DD D + D++D+ D++ + E E +N
Sbjct: 246 EEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDEDDEDEEDGEEEN 290
Score = 28.5 bits (62), Expect = 7.3
Identities = 21/85 (24%), Positives = 41/85 (48%), Gaps = 6/85 (7%)
Query: 1 MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
M +R K++ + Q D ++E E E ED + D +DE+DE D++ + +
Sbjct: 218 MYTRGKQKDI-----QRTDEETTDNQEGSVESSEEGEDQEHEDDGEDEDDEDDDDDDDDD 272
Query: 61 FEAYSLSDND-YDGIKKLLQQLFLK 84
+ D D DG ++ ++ +L+
Sbjct: 273 DDDDDEDDEDEEDGEEENQKRYYLR 297
>gi|58331272 zinc finger, CCHC domain containing 6 [Homo sapiens]
Length = 1495
Score = 40.0 bits (92), Expect = 0.002
Identities = 39/179 (21%), Positives = 79/179 (44%), Gaps = 20/179 (11%)
Query: 25 DEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKKLLQQLFLK 84
+EEE+ E E E+E+ + ++++ED + +E+ E + D D + + +L
Sbjct: 846 EEEEDDEEEEEEEEPRLTINQREDEDGMANED---ELDNTYTGSGDEDALSEEDDELGEA 902
Query: 85 APVNTAELTD------LLIQQNHIGSVIKQTDVSEDSNDDMDEDEVFGFISLLNLTERKG 138
A + LL++ N I +K+ +V E+ N +D+ + F S L T+ K
Sbjct: 903 AKYEDVKECGKHVERALLVELNKIS--LKEENVCEEKNSPVDQSDFFYEFSKLIFTKGKS 960
Query: 139 TQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLLSERFINVPPQIALPMYQ 197
V + + E + +K E + + P L+ +F+N+ Q+ + Y+
Sbjct: 961 PTVVCSLCKR-----EGHLKKDCPEDFKRIQLEPLPP----LTPKFLNILDQVCIQCYK 1010
>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
Length = 740
Score = 39.7 bits (91), Expect = 0.003
Identities = 23/59 (38%), Positives = 35/59 (59%), Gaps = 4/59 (6%)
Query: 23 QRDEEEEKEVENEDEDDDDSDKEKD----EEDEVIDEEVNIEFEAYSLSDNDYDGIKKL 77
+ DEEEE+E E E+E+ DS++E+D +E + DEE + E EA + D D + L
Sbjct: 442 ESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSL 500
Score = 34.3 bits (77), Expect = 0.13
Identities = 13/24 (54%), Positives = 21/24 (87%)
Query: 33 ENEDEDDDDSDKEKDEEDEVIDEE 56
E +DEDD++SD+E++EE+E +EE
Sbjct: 434 ETDDEDDEESDEEEEEEEEEEEEE 457
Score = 33.9 bits (76), Expect = 0.17
Identities = 14/49 (28%), Positives = 30/49 (61%)
Query: 12 SGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
SG+ P R E ++++ E DE++++ ++E++EE +EE ++E
Sbjct: 420 SGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLE 468
>gi|215422388 death-domain associated protein isoform a [Homo
sapiens]
Length = 740
Score = 39.7 bits (91), Expect = 0.003
Identities = 23/59 (38%), Positives = 35/59 (59%), Gaps = 4/59 (6%)
Query: 23 QRDEEEEKEVENEDEDDDDSDKEKD----EEDEVIDEEVNIEFEAYSLSDNDYDGIKKL 77
+ DEEEE+E E E+E+ DS++E+D +E + DEE + E EA + D D + L
Sbjct: 442 ESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSL 500
Score = 34.3 bits (77), Expect = 0.13
Identities = 13/24 (54%), Positives = 21/24 (87%)
Query: 33 ENEDEDDDDSDKEKDEEDEVIDEE 56
E +DEDD++SD+E++EE+E +EE
Sbjct: 434 ETDDEDDEESDEEEEEEEEEEEEE 457
Score = 33.9 bits (76), Expect = 0.17
Identities = 14/49 (28%), Positives = 30/49 (61%)
Query: 12 SGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
SG+ P R E ++++ E DE++++ ++E++EE +EE ++E
Sbjct: 420 SGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLE 468
>gi|215422366 death-domain associated protein isoform b [Homo
sapiens]
Length = 752
Score = 39.7 bits (91), Expect = 0.003
Identities = 23/59 (38%), Positives = 35/59 (59%), Gaps = 4/59 (6%)
Query: 23 QRDEEEEKEVENEDEDDDDSDKEKD----EEDEVIDEEVNIEFEAYSLSDNDYDGIKKL 77
+ DEEEE+E E E+E+ DS++E+D +E + DEE + E EA + D D + L
Sbjct: 454 ESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSL 512
Score = 34.3 bits (77), Expect = 0.13
Identities = 13/24 (54%), Positives = 21/24 (87%)
Query: 33 ENEDEDDDDSDKEKDEEDEVIDEE 56
E +DEDD++SD+E++EE+E +EE
Sbjct: 446 ETDDEDDEESDEEEEEEEEEEEEE 469
Score = 33.9 bits (76), Expect = 0.17
Identities = 14/49 (28%), Positives = 30/49 (61%)
Query: 12 SGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
SG+ P R E ++++ E DE++++ ++E++EE +EE ++E
Sbjct: 432 SGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLE 480
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.132 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,727,102
Number of Sequences: 37866
Number of extensions: 666728
Number of successful extensions: 17391
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 487
Number of HSP's successfully gapped in prelim test: 222
Number of HSP's that attempted gapping in prelim test: 6859
Number of HSP's gapped (non-prelim): 5189
length of query: 292
length of database: 18,247,518
effective HSP length: 101
effective length of query: 191
effective length of database: 14,423,052
effective search space: 2754802932
effective search space used: 2754802932
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.