Search of human proteins with 17402871

Search of human proteins with 17402871

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|17402871 BRCA2 and CDKN1A-interacting protein isoform
BCCIPbeta [Homo sapiens]
         (314 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|17402871 BRCA2 and CDKN1A-interacting protein isoform BCCIPbe...   630   0.0  
gi|17402873 BRCA2 and CDKN1A-interacting protein isoform C [Homo...   518   e-147
gi|7706581 BRCA2 and CDKN1A-interacting protein isoform BCCIPalp...   518   e-147
gi|158631177 homeodomain leucine zipper protein [Homo sapiens]         47   3e-05
gi|58761548 tau tubulin kinase 1 [Homo sapiens]                        45   6e-05
gi|21361639 DIPB protein [Homo sapiens]                                45   1e-04
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]           45   1e-04
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]           45   1e-04
gi|17975763 myelin transcription factor 1 [Homo sapiens]               44   1e-04
gi|60498973 myelin transcription factor 1-like [Homo sapiens]          44   1e-04
gi|55956788 nucleolin [Homo sapiens]                                   44   2e-04
gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo ...    44   2e-04
gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo ...    44   2e-04
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...    44   2e-04
gi|51477718 TATA box binding protein-associated factor, RNA poly...    42   5e-04
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil...    42   7e-04
gi|13654270 LAS1-like [Homo sapiens]                                   42   0.001
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    41   0.001
gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens]    41   0.001
gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens]       41   0.002
gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens]       41   0.002
gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens]        41   0.002
gi|210032580 SET domain containing 1B [Homo sapiens]                   41   0.002
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]       40   0.002
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo...    40   0.002
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]      40   0.003
gi|58331272 zinc finger, CCHC domain containing 6 [Homo sapiens]       40   0.003
gi|4503257 death-domain associated protein isoform a [Homo sapiens]    40   0.004
gi|215422388 death-domain associated protein isoform a [Homo sap...    40   0.004
gi|215422366 death-domain associated protein isoform b [Homo sap...    40   0.004

>gi|17402871 BRCA2 and CDKN1A-interacting protein isoform BCCIPbeta
           [Homo sapiens]
          Length = 314

 Score =  630 bits (1626), Expect = 0.0
 Identities = 314/314 (100%), Positives = 314/314 (100%)

Query: 1   MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
           MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE
Sbjct: 1   MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60

Query: 61  FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD 120
           FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD
Sbjct: 61  FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD 120

Query: 121 EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLL 180
           EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLL
Sbjct: 121 EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLL 180

Query: 181 SERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSN 240
           SERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSN
Sbjct: 181 SERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSN 240

Query: 241 KKKAALMFANAEEEFFYEKAILKFNYSVQEESDTCLGGKWSFDDVPMTPLRTVMLIPGDK 300
           KKKAALMFANAEEEFFYEKAILKFNYSVQEESDTCLGGKWSFDDVPMTPLRTVMLIPGDK
Sbjct: 241 KKKAALMFANAEEEFFYEKAILKFNYSVQEESDTCLGGKWSFDDVPMTPLRTVMLIPGDK 300

Query: 301 MNEIMDKLKEYLSV 314
           MNEIMDKLKEYLSV
Sbjct: 301 MNEIMDKLKEYLSV 314


>gi|17402873 BRCA2 and CDKN1A-interacting protein isoform C [Homo
           sapiens]
          Length = 292

 Score =  518 bits (1333), Expect = e-147
 Identities = 258/259 (99%), Positives = 259/259 (100%)

Query: 1   MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
           MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE
Sbjct: 1   MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60

Query: 61  FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD 120
           FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD
Sbjct: 61  FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD 120

Query: 121 EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLL 180
           EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLL
Sbjct: 121 EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLL 180

Query: 181 SERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSN 240
           SERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSN
Sbjct: 181 SERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSN 240

Query: 241 KKKAALMFANAEEEFFYEK 259
           KKKAALMFANAEEEFFYE+
Sbjct: 241 KKKAALMFANAEEEFFYEE 259


>gi|7706581 BRCA2 and CDKN1A-interacting protein isoform BCCIPalpha
           [Homo sapiens]
          Length = 322

 Score =  518 bits (1333), Expect = e-147
 Identities = 258/259 (99%), Positives = 259/259 (100%)

Query: 1   MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
           MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE
Sbjct: 1   MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60

Query: 61  FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD 120
           FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD
Sbjct: 61  FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD 120

Query: 121 EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLL 180
           EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLL
Sbjct: 121 EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLL 180

Query: 181 SERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSN 240
           SERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSN
Sbjct: 181 SERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSN 240

Query: 241 KKKAALMFANAEEEFFYEK 259
           KKKAALMFANAEEEFFYE+
Sbjct: 241 KKKAALMFANAEEEFFYEE 259


>gi|158631177 homeodomain leucine zipper protein [Homo sapiens]
          Length = 550

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 21/50 (42%), Positives = 36/50 (72%)

Query: 11  ESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
           +S +PQP +  V  DEEEE+E E   EDD++ ++E++E+D+  D++V I+
Sbjct: 500 DSRLPQPAEVVVCLDEEEEEEEEELPEDDEEEEEEEEEDDDDDDDDVIIQ 549


>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
          Length = 1321

 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 24/55 (43%), Positives = 36/55 (65%), Gaps = 6/55 (10%)

Query: 15  PQPPDPPVQ------RDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEA 63
           PQ P  PVQ       +EEEE+E E E+E+D++ ++E++EE+E  +EE   E EA
Sbjct: 718 PQVPLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEA 772



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 18/49 (36%), Positives = 32/49 (65%)

Query: 14  VPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62
           VP  P  P    +EEE+E E ++E++++ ++E++EE+E  +EE   E E
Sbjct: 720 VPLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEE 768



 Score = 28.9 bits (63), Expect = 6.2
 Identities = 12/33 (36%), Positives = 23/33 (69%)

Query: 25  DEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEV 57
           +EEEE+E E E+E++++ ++E++    V   EV
Sbjct: 749 EEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEV 781


>gi|21361639 DIPB protein [Homo sapiens]
          Length = 344

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 22/68 (32%), Positives = 37/68 (54%), Gaps = 5/68 (7%)

Query: 6   KRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYS 65
           + R +ES   +  +   + + EEE E E E ED+ D + E+D E+E+ DE+     E+ +
Sbjct: 87  QEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQ-----ESEA 141

Query: 66  LSDNDYDG 73
             DN  +G
Sbjct: 142 EEDNQEEG 149



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 13/50 (26%), Positives = 28/50 (56%)

Query: 23  QRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYD 72
           +  E+E  E   ED +++  D+++ E +E   EE   E E  + +++++D
Sbjct: 115 EESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFD 164



 Score = 30.4 bits (67), Expect = 2.1
 Identities = 18/62 (29%), Positives = 30/62 (48%), Gaps = 3/62 (4%)

Query: 11  ESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDND 70
           ES   +  +     + EE+ E E EDE + +++++  EE E    E   E EA S  D +
Sbjct: 110 ESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGE---SEAEGETEAESEFDPE 166

Query: 71  YD 72
            +
Sbjct: 167 IE 168



 Score = 30.0 bits (66), Expect = 2.8
 Identities = 15/44 (34%), Positives = 29/44 (65%), Gaps = 1/44 (2%)

Query: 27  EEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDND 70
           E+E+E+E+E  ++ +S++E + E+E   EE + E E+   S+ D
Sbjct: 86  EQEREIESEAGEESESEEESESEEESETEEES-EDESDEESEED 128


>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
          Length = 709

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 21/70 (30%), Positives = 41/70 (58%), Gaps = 2/70 (2%)

Query: 3   SRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62
           + ++   VE  V +  D  V+ D EE++EV+ + E++++ ++E++EE+E  +EE   +  
Sbjct: 198 TENEEEGVEEDVEE--DEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDER 255

Query: 63  AYSLSDNDYD 72
                 NDYD
Sbjct: 256 DQKEEGNDYD 265



 Score = 37.0 bits (84), Expect = 0.023
 Identities = 16/47 (34%), Positives = 30/47 (63%)

Query: 19  DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYS 65
           D  V  D EEE+E E E+E++++ ++E+ E+DE   +E   +++  S
Sbjct: 222 DEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRS 268



 Score = 33.1 bits (74), Expect = 0.33
 Identities = 14/42 (33%), Positives = 26/42 (61%)

Query: 19  DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
           D   + +EEEE+E E E+E+++    E+D+++E  D +   E
Sbjct: 228 DGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSE 269



 Score = 30.4 bits (67), Expect = 2.1
 Identities = 15/46 (32%), Positives = 25/46 (54%)

Query: 23  QRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSD 68
           + +EEEE+E E E E D+   KE+  + +   E  +   E+ S +D
Sbjct: 237 EEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTD 282


>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
          Length = 727

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 21/70 (30%), Positives = 41/70 (58%), Gaps = 2/70 (2%)

Query: 3   SRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62
           + ++   VE  V +  D  V+ D EE++EV+ + E++++ ++E++EE+E  +EE   +  
Sbjct: 198 TENEEEGVEEDVEE--DEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDER 255

Query: 63  AYSLSDNDYD 72
                 NDYD
Sbjct: 256 DQKEEGNDYD 265



 Score = 37.0 bits (84), Expect = 0.023
 Identities = 16/47 (34%), Positives = 30/47 (63%)

Query: 19  DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYS 65
           D  V  D EEE+E E E+E++++ ++E+ E+DE   +E   +++  S
Sbjct: 222 DEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRS 268



 Score = 33.1 bits (74), Expect = 0.33
 Identities = 14/42 (33%), Positives = 26/42 (61%)

Query: 19  DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
           D   + +EEEE+E E E+E+++    E+D+++E  D +   E
Sbjct: 228 DGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSE 269



 Score = 30.4 bits (67), Expect = 2.1
 Identities = 15/46 (32%), Positives = 25/46 (54%)

Query: 23  QRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSD 68
           + +EEEE+E E E E D+   KE+  + +   E  +   E+ S +D
Sbjct: 237 EEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTD 282


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 39/165 (23%), Positives = 72/165 (43%), Gaps = 9/165 (5%)

Query: 5   SKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEA- 63
           SK++ + S   +  +   + +EEEE E E E+E++++ ++E++EE+E  +EE   E EA 
Sbjct: 249 SKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAA 308

Query: 64  ---YSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD 120
                  D  +   +K  +   L+ P + +   +  +         K  D     +   D
Sbjct: 309 PDVIFQEDTSHTSAQKAPE---LRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTD 365

Query: 121 EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQL 165
           E E+   ++  NL   +  Q +    E V   CE  C  +   QL
Sbjct: 366 ESEMQDMMTRGNLGLLE--QAIALKAEQVRTVCEPGCPPAEQSQL 408



 Score = 32.3 bits (72), Expect = 0.56
 Identities = 13/48 (27%), Positives = 29/48 (60%)

Query: 15  PQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62
           PQ  +     +  ++K + + +E+D++ ++E++EE+E  +EE   E E
Sbjct: 237 PQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEE 284


>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
          Length = 1184

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 39/138 (28%), Positives = 65/138 (47%), Gaps = 17/138 (12%)

Query: 11  ESGVPQPPDPPVQRDEEEEKEVENEDEDDD--DSDKEKDEEDEVIDEEVNIEFEAYSLS- 67
           E G     D    R+EEEE E E+ED+D+D  D + E++EE+E  +EE   E E + ++ 
Sbjct: 116 EPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNC 175

Query: 68  ------------DNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDS 115
                       DN+ D       +L  K+ +N  ++ +    +    S +  ++ S   
Sbjct: 176 HNTRIMQDTEKDDNNNDEYDN-YDELVAKSLLNLGKIAEDAAYRARTESEM-NSNTSNSL 233

Query: 116 NDDMDEDEVFGFISLLNL 133
            DD D++E  G  S L+L
Sbjct: 234 EDDSDKNENLGRKSELSL 251



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 35/129 (27%), Positives = 61/129 (47%), Gaps = 4/129 (3%)

Query: 8   RAVESGVPQPPDPPVQRDEEEEKEVENED-EDDDDSDKEKDEEDEVIDEEVNIEFEAYSL 66
           +A  S V +  D     D +E++E E E+  +D+D   ++DEEDE  D E   E E    
Sbjct: 81  KADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEED- 139

Query: 67  SDNDYDG--IKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMDEDEV 124
            D+D DG  ++   ++   +      E  +      H   +++ T+  +++ND+ D  + 
Sbjct: 140 EDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDE 199

Query: 125 FGFISLLNL 133
               SLLNL
Sbjct: 200 LVAKSLLNL 208


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 17/35 (48%), Positives = 28/35 (80%)

Query: 22  VQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEE 56
           V  DE+EE++ E+ED+DDD+ D++ D+ED+  +EE
Sbjct: 232 VAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEE 266



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 17/37 (45%), Positives = 28/37 (75%)

Query: 26  EEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62
           E+E++E ++EDEDDDD + ++D++DE  +EE   E E
Sbjct: 234 EDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEE 270



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 38/137 (27%), Positives = 58/137 (42%), Gaps = 24/137 (17%)

Query: 2   ASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDE---------------DDDDSDKEK 46
           A   K    E    +  D   + +E++E E E+EDE               +D+D + ++
Sbjct: 134 AKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDE 193

Query: 47  DEEDEVIDEEVNIEFEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVI 106
           D+ED+  DEE + E EA   +       KK  + + +KA  N AE  D            
Sbjct: 194 DDEDDDDDEEDDSEEEAMETTPAKG---KKAAKVVPVKAK-NVAEDED-----EEEDDED 244

Query: 107 KQTDVSEDSNDDMDEDE 123
           +  D  ED  DD DED+
Sbjct: 245 EDDDDDEDDEDDDDEDD 261



 Score = 38.1 bits (87), Expect = 0.010
 Identities = 17/43 (39%), Positives = 27/43 (62%)

Query: 20  PPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62
           P   ++  E+++ E +DED+DD D E DE+D+  D+E   E E
Sbjct: 226 PVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEE 268



 Score = 37.7 bits (86), Expect = 0.013
 Identities = 14/39 (35%), Positives = 28/39 (71%)

Query: 19  DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEV 57
           D   + D+E+E + ++ED++DDD + +++EE+E  +E V
Sbjct: 235 DEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPV 273



 Score = 36.2 bits (82), Expect = 0.039
 Identities = 33/149 (22%), Positives = 52/149 (34%), Gaps = 32/149 (21%)

Query: 18  PDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKKL 77
           P    +  +  +KE  +E+EDDD  + E+D+EDE                D D D I+  
Sbjct: 130 PAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDE----------------DEDEDEIEPA 173

Query: 78  LQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMDEDEVFGFISLLNLTERK 137
             +    AP +  E                  +  ED  DD D++E       +  T  K
Sbjct: 174 AMKAAAAAPASEDE----------------DDEDDEDDEDDDDDEEDDSEEEAMETTPAK 217

Query: 138 GTQCVEQIQELVLRFCEKNCEKSMVEQLD 166
           G +  + +        E   E+   E  D
Sbjct: 218 GKKAAKVVPVKAKNVAEDEDEEEDDEDED 246



 Score = 32.7 bits (73), Expect = 0.43
 Identities = 12/44 (27%), Positives = 28/44 (63%)

Query: 6   KRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEE 49
           K + V     +  D   + D+++E + +++DEDD++ ++E++EE
Sbjct: 228 KAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEE 271



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 11/42 (26%), Positives = 28/42 (66%)

Query: 35  EDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKK 76
           EDED+++ D+++D++D+  DE+ + E +     + + + +K+
Sbjct: 234 EDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKE 275



 Score = 29.6 bits (65), Expect = 3.6
 Identities = 12/26 (46%), Positives = 18/26 (69%)

Query: 20 PPVQRDEEEEKEVENEDEDDDDSDKE 45
          PP + +E+ E E  +EDE+DD S +E
Sbjct: 20 PPKEVEEDSEDEEMSEDEEDDSSGEE 45


>gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo
            sapiens]
          Length = 5033

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 22/69 (31%), Positives = 41/69 (59%)

Query: 19   DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKKLL 78
            +P V  +EEEE++ E E E++D+ +KE+DEE+   ++E   + E  +      +G+++ L
Sbjct: 1867 EPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEKEEGLEEGL 1926

Query: 79   QQLFLKAPV 87
             Q+ L   V
Sbjct: 1927 LQMKLPESV 1935



 Score = 30.0 bits (66), Expect = 2.8
 Identities = 14/49 (28%), Positives = 27/49 (55%)

Query: 8    RAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEE 56
            + +E  V    +     +EE E+E E E E+D++   ++ E++E  +EE
Sbjct: 1864 KMIEPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEE 1912


>gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo
            sapiens]
          Length = 5038

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 22/69 (31%), Positives = 41/69 (59%)

Query: 19   DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKKLL 78
            +P V  +EEEE++ E E E++D+ +KE+DEE+   ++E   + E  +      +G+++ L
Sbjct: 1867 EPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEKEEGLEEGL 1926

Query: 79   QQLFLKAPV 87
             Q+ L   V
Sbjct: 1927 LQMKLPESV 1935



 Score = 30.0 bits (66), Expect = 2.8
 Identities = 14/49 (28%), Positives = 27/49 (55%)

Query: 8    RAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEE 56
            + +E  V    +     +EE E+E E E E+D++   ++ E++E  +EE
Sbjct: 1864 KMIEPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEE 1912


>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
            [Homo sapiens]
          Length = 2073

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 20/54 (37%), Positives = 35/54 (64%)

Query: 23   QRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKK 76
            + +EEEE E E E+E++++ D+E++EE+E  +EE NI+     L+      IK+
Sbjct: 1070 EEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKR 1123



 Score = 37.4 bits (85), Expect = 0.017
 Identities = 14/34 (41%), Positives = 27/34 (79%)

Query: 23   QRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEE 56
            +   EEE+E E+E+E++++ ++E+DEE+E  +EE
Sbjct: 1066 KESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEE 1099



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 20/66 (30%), Positives = 35/66 (53%)

Query: 4    RSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEA 63
            +SK + + S   +P      +  E  KE   E+E+++D ++E++EE+E  DEE   E E 
Sbjct: 1040 QSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEE 1099

Query: 64   YSLSDN 69
                +N
Sbjct: 1100 EEEEEN 1105



 Score = 33.5 bits (75), Expect = 0.25
 Identities = 13/48 (27%), Positives = 31/48 (64%)

Query: 22   VQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDN 69
            ++  +E  +E E E++++++ ++E++EEDE  +EE   E E  ++  +
Sbjct: 1062 LELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSS 1109



 Score = 33.1 bits (74), Expect = 0.33
 Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 5/92 (5%)

Query: 14   VPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDG 73
            V + PD   +  E+EE E+  E ED    D  ++EE+E  +   N + +A    D+  + 
Sbjct: 1378 VEKDPDG-AKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMES 1436

Query: 74   I----KKLLQQLFLKAPVNTAELTDLLIQQNH 101
                 ++L ++ F +   N     DL +Q  H
Sbjct: 1437 AEVEKEELPRESFKEVLENQETFLDLNVQPGH 1468



 Score = 32.0 bits (71), Expect = 0.73
 Identities = 25/120 (20%), Positives = 53/120 (44%), Gaps = 10/120 (8%)

Query: 4    RSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEA 63
            + + R  E+  P  P+       E++     E+E++++ ++E++EE+E  +EE     E 
Sbjct: 1321 QEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVE- 1379

Query: 64   YSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMDEDE 123
                  D DG K   ++     P  + E  D     +H     +  + S + + D D+++
Sbjct: 1380 -----KDPDGAKSQEKE----EPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDED 1430



 Score = 30.4 bits (67), Expect = 2.1
 Identities = 15/73 (20%), Positives = 38/73 (52%)

Query: 3    SRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62
            S +K ++    +  P   PV  +  +  E+  E  ++++ +++++EE+E  +EE + E E
Sbjct: 1035 SPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEE 1094

Query: 63   AYSLSDNDYDGIK 75
                 + + + I+
Sbjct: 1095 EEEEEEEEEENIQ 1107


>gi|51477718 TATA box binding protein-associated factor, RNA
           polymerase II, Q [Homo sapiens]
          Length = 462

 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 29/115 (25%), Positives = 56/115 (48%), Gaps = 15/115 (13%)

Query: 19  DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEF---EAYSLSDNDYDGIK 75
           D     D+E+E E E+EDED+D  ++E+D  +E ++ ++  EF     Y  ++     + 
Sbjct: 333 DDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLERQLQAEFIESGQYRANEGTSSIVM 392

Query: 76  KLLQQLFLKAP-----VNTAELTDLLIQ-------QNHIGSVIKQTDVSEDSNDD 118
           ++ +Q+  K        N A+    LI        +NH  SV++Q ++ E   ++
Sbjct: 393 EIQKQIEKKEKKLHKIQNKAQRQKDLIMKVENLTLKNHFQSVLEQLELQEKQKNE 447



 Score = 37.4 bits (85), Expect = 0.017
 Identities = 39/149 (26%), Positives = 75/149 (50%), Gaps = 13/149 (8%)

Query: 24  RDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKKLLQQLFL 83
           R+   +    N+D++D+D + E ++EDE  DE+   E E     D   + +++ LQ  F+
Sbjct: 322 REMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEE-----DCSEEYLERQLQAEFI 376

Query: 84  KAPVNTA-ELTDLLIQQNHIGSVIKQTDVSEDSNDDMDEDEVFGFISLLNLTERKGTQCV 142
           ++    A E T  ++ +       K+  + +  N    + ++   + + NLT +   Q V
Sbjct: 377 ESGQYRANEGTSSIVMEIQKQIEKKEKKLHKIQNKAQRQKDL--IMKVENLTLKNHFQSV 434

Query: 143 EQIQELVLRFCEKNCEK--SMVEQLDKFL 169
             +++L L+  +KN EK  S+ EQL +FL
Sbjct: 435 --LEQLELQEKQKN-EKLISLQEQLQRFL 460


>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member B [Homo sapiens]
          Length = 251

 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 24/59 (40%), Positives = 34/59 (57%), Gaps = 11/59 (18%)

Query: 25  DEEEEKEVENEDEDDDDSD------KEKDEEDEVI-----DEEVNIEFEAYSLSDNDYD 72
           DEEEE E   ++ED+DD D       E+D+EDE +     D+EV+ E E + L + D D
Sbjct: 166 DEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDED 224



 Score = 33.5 bits (75), Expect = 0.25
 Identities = 21/56 (37%), Positives = 31/56 (55%), Gaps = 4/56 (7%)

Query: 11  ESGVPQPPDPPVQRDEEEEKEVENEDED---DDDSDKEKDEEDEV-IDEEVNIEFE 62
           E G  +  +     +EEE  E ++EDED   D+D D+  +EE+E  +DEE   E E
Sbjct: 172 EEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDE 227



 Score = 33.1 bits (74), Expect = 0.33
 Identities = 14/36 (38%), Positives = 28/36 (77%), Gaps = 4/36 (11%)

Query: 25  DEEEEKEVENEDEDDDDSDKEK----DEEDEVIDEE 56
           +++E+++VE +++DD+ S++E+    DEEDE  DE+
Sbjct: 193 EDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDED 228



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 19/55 (34%), Positives = 29/55 (52%), Gaps = 4/55 (7%)

Query: 19  DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDG 73
           D      + E   V+ E+ED++  D E+DE+DE  +EE   EF+     D D +G
Sbjct: 152 DQEAPDSDAEVDGVDEEEEDEEGED-EEDEDDEDGEEE---EFDEEDDEDEDVEG 202



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 15/37 (40%), Positives = 26/37 (70%), Gaps = 5/37 (13%)

Query: 19  DPPVQRDEEEEKEVENEDE----DDDDSDKEKDEEDE 51
           D  V+ DE+++ EV  E+E    D++D D+++DEE+E
Sbjct: 197 DEDVEGDEDDD-EVSEEEEEFGLDEEDEDEDEDEEEE 232


>gi|13654270 LAS1-like [Homo sapiens]
          Length = 734

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 21/49 (42%), Positives = 33/49 (67%), Gaps = 5/49 (10%)

Query: 22  VQRDEEEEKEV-----ENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYS 65
           V+ +E+EEKEV     E E+E+DD  ++E+DE+DE  +EE  +E   +S
Sbjct: 564 VKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRMEVGPFS 612



 Score = 33.9 bits (76), Expect = 0.19
 Identities = 14/33 (42%), Positives = 21/33 (63%)

Query: 20  PPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEV 52
           P    +EEE  + E E+ED+DD D E+++  EV
Sbjct: 576 PDQVEEEEENDDQEEEEEDEDDEDDEEEDRMEV 608



 Score = 33.1 bits (74), Expect = 0.33
 Identities = 12/28 (42%), Positives = 20/28 (71%)

Query: 18  PDPPVQRDEEEEKEVENEDEDDDDSDKE 45
           PD   + +E +++E E EDEDD+D ++E
Sbjct: 576 PDQVEEEEENDDQEEEEEDEDDEDDEEE 603



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 10/31 (32%), Positives = 21/31 (67%)

Query: 14  VPQPPDPPVQRDEEEEKEVENEDEDDDDSDK 44
           +P   +   + D++EE+E + +DEDD++ D+
Sbjct: 575 LPDQVEEEEENDDQEEEEEDEDDEDDEEEDR 605


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 17/44 (38%), Positives = 31/44 (70%)

Query: 19  DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62
           D   + +EEEE+E E E+E+++D ++E+++E+E  +EE   E E
Sbjct: 887 DEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEE 930



 Score = 38.1 bits (87), Expect = 0.010
 Identities = 15/38 (39%), Positives = 28/38 (73%)

Query: 23  QRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
           + +EEEE++ E E+ED+++  +E++EE+E  +EE   E
Sbjct: 901 EEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEE 938



 Score = 37.4 bits (85), Expect = 0.017
 Identities = 19/54 (35%), Positives = 33/54 (61%), Gaps = 1/54 (1%)

Query: 10  VESGVPQPPDPPVQRDEEEEKEVENED-EDDDDSDKEKDEEDEVIDEEVNIEFE 62
           + S   +  +   + +EEEE+E E ED E++++ ++E  EE+E  +EE   EFE
Sbjct: 883 INSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFE 936



 Score = 36.6 bits (83), Expect = 0.030
 Identities = 16/51 (31%), Positives = 32/51 (62%)

Query: 23  QRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDG 73
           + +EEEE+E E E+E++++  +E++E++E   EE   E E +     + +G
Sbjct: 890 EEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEG 940



 Score = 35.4 bits (80), Expect = 0.066
 Identities = 15/53 (28%), Positives = 30/53 (56%)

Query: 10  VESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62
           V  G P    PP   ++     + + DE++++ ++E++EE+E  +EE + E E
Sbjct: 861 VPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEE 913



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 1/79 (1%)

Query: 8    RAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLS 67
            R  ES    PP   +  +E        E+E +D SDK +   +   +EE+  E EA +L 
Sbjct: 1039 REGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQ 1098

Query: 68   DNDYDGIKKLLQQLFLKAP 86
            + + D    +L   F+  P
Sbjct: 1099 EKEQDDTAAMLAD-FIDCP 1116



 Score = 34.3 bits (77), Expect = 0.15
 Identities = 15/36 (41%), Positives = 28/36 (77%), Gaps = 1/36 (2%)

Query: 23  QRDEEEEKEVENE-DEDDDDSDKEKDEEDEVIDEEV 57
           + +EEEE+E E E +E++ + ++E++EEDE  +EE+
Sbjct: 922 EEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEEL 957



 Score = 33.1 bits (74), Expect = 0.33
 Identities = 16/37 (43%), Positives = 24/37 (64%)

Query: 26  EEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62
           EEEE+E E  +E+ ++ + E +EE+E  DEE   E E
Sbjct: 922 EEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELE 958



 Score = 32.7 bits (73), Expect = 0.43
 Identities = 13/40 (32%), Positives = 28/40 (70%)

Query: 23  QRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62
           + +E+EE+  E E+E++++ ++E +EE+  ++EE   E E
Sbjct: 912 EEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDE 951



 Score = 32.0 bits (71), Expect = 0.73
 Identities = 13/36 (36%), Positives = 26/36 (72%)

Query: 25  DEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
           +EEEE+E   E+ ++++ + E++EE+E  +EE  +E
Sbjct: 923 EEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELE 958



 Score = 28.5 bits (62), Expect = 8.1
 Identities = 11/55 (20%), Positives = 34/55 (61%)

Query: 23  QRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKKL 77
           + ++ EE+E + E+  +++ ++E++ E+E  +EE  +E E     + + + ++++
Sbjct: 906 EEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEV 960


>gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens]
          Length = 619

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 17/42 (40%), Positives = 30/42 (71%)

Query: 19  DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
           +P     EE++KE +++DEDDDD + E++EE+E  D++ + E
Sbjct: 128 EPGGDGGEEDDKEDDDDDEDDDDEEDEEEEEEEEEDDDDDTE 169



 Score = 38.1 bits (87), Expect = 0.010
 Identities = 16/45 (35%), Positives = 31/45 (68%)

Query: 25  DEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDN 69
           D  EE + E++D+D+DD D+E +EE+E  +E+ + + E ++  +N
Sbjct: 132 DGGEEDDKEDDDDDEDDDDEEDEEEEEEEEEDDDDDTEDFADQEN 176



 Score = 33.9 bits (76), Expect = 0.19
 Identities = 13/32 (40%), Positives = 23/32 (71%)

Query: 25  DEEEEKEVENEDEDDDDSDKEKDEEDEVIDEE 56
           DEE+E+E E E+EDDDD  ++  +++ + D +
Sbjct: 150 DEEDEEEEEEEEEDDDDDTEDFADQENLPDPQ 181



 Score = 33.5 bits (75), Expect = 0.25
 Identities = 14/35 (40%), Positives = 23/35 (65%)

Query: 25  DEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNI 59
           D+EE++E E E+E+DDD D E   + E + +  +I
Sbjct: 149 DDEEDEEEEEEEEEDDDDDTEDFADQENLPDPQDI 183



 Score = 32.7 bits (73), Expect = 0.43
 Identities = 12/41 (29%), Positives = 27/41 (65%)

Query: 30  KEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDND 70
           +E + ED+DDD+ D ++++E+E  +EE + + +    +D +
Sbjct: 135 EEDDKEDDDDDEDDDDEEDEEEEEEEEEDDDDDTEDFADQE 175


>gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 26/104 (25%), Positives = 53/104 (50%), Gaps = 6/104 (5%)

Query: 2   ASRSKRRAVESGVPQPPDPPVQRDEEEEKEV-ENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
           A   + R   +G  +  +P  + +EEEE+E  E E+E+DDD   +K      I +E +++
Sbjct: 24  AEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVD 83

Query: 61  FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGS 104
            E Y   D   DG + +L+    K  +  + + ++++ ++  G+
Sbjct: 84  DE-YEDEDQWEDGAEDILE----KEEIEASNIDNVVLDEDRSGA 122


>gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 26/104 (25%), Positives = 53/104 (50%), Gaps = 6/104 (5%)

Query: 2   ASRSKRRAVESGVPQPPDPPVQRDEEEEKEV-ENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
           A   + R   +G  +  +P  + +EEEE+E  E E+E+DDD   +K      I +E +++
Sbjct: 24  AEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVD 83

Query: 61  FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGS 104
            E Y   D   DG + +L+    K  +  + + ++++ ++  G+
Sbjct: 84  DE-YEDEDQWEDGAEDILE----KEEIEASNIDNVVLDEDRSGA 122


>gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 26/104 (25%), Positives = 53/104 (50%), Gaps = 6/104 (5%)

Query: 2   ASRSKRRAVESGVPQPPDPPVQRDEEEEKEV-ENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
           A   + R   +G  +  +P  + +EEEE+E  E E+E+DDD   +K      I +E +++
Sbjct: 24  AEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVD 83

Query: 61  FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGS 104
            E Y   D   DG + +L+    K  +  + + ++++ ++  G+
Sbjct: 84  DE-YEDEDQWEDGAEDILE----KEEIEASNIDNVVLDEDRSGA 122


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 21/48 (43%), Positives = 28/48 (58%), Gaps = 1/48 (2%)

Query: 25   DEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYD 72
            +EEEE E E E+EDDDD D +  +E E  DE+  +  EA    + D D
Sbjct: 1049 EEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALS-EASEKDEGDSD 1095



 Score = 29.6 bits (65), Expect = 3.6
 Identities = 10/34 (29%), Positives = 22/34 (64%)

Query: 16   QPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEE 49
            +PPD     D++  +   + DE+D++S++E+D +
Sbjct: 968  EPPDTTSSGDQKRLRPSTSVDEEDEESERERDRD 1001



 Score = 29.3 bits (64), Expect = 4.7
 Identities = 20/49 (40%), Positives = 29/49 (59%), Gaps = 4/49 (8%)

Query: 25   DEEEEKEVENEDEDDDDSD-KEKDEEDEVIDEEVNI---EFEAYSLSDN 69
            D ++  E EN+DED   S+  EKDE D   +E V+I   + EA S S++
Sbjct: 1067 DSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSES 1115


>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
          Length = 4374

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 22/63 (34%), Positives = 35/63 (55%), Gaps = 2/63 (3%)

Query: 18   PDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKKL 77
            P+   +  +EE+    NEDEDD   ++E++EEDE  D+E +   E     D+D DG +  
Sbjct: 2409 PEDEEEHTQEEDSSGSNEDEDDSQDEEEEEEEDEEDDQEDDEGEEGD--EDDDDDGSEME 2466

Query: 78   LQQ 80
            L +
Sbjct: 2467 LDE 2469



 Score = 37.0 bits (84), Expect = 0.023
 Identities = 19/54 (35%), Positives = 31/54 (57%), Gaps = 2/54 (3%)

Query: 19   DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYD 72
            DP  + +  +E++    +ED+DDS  E++EE+E  DEE + E +     D D D
Sbjct: 2408 DPEDEEEHTQEEDSSGSNEDEDDSQDEEEEEEE--DEEDDQEDDEGEEGDEDDD 2459



 Score = 36.2 bits (82), Expect = 0.039
 Identities = 14/50 (28%), Positives = 32/50 (64%)

Query: 12   SGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEF 61
            SG  +  D     +EEEE++ E++ EDD+  + ++D++D+  + E++ ++
Sbjct: 2422 SGSNEDEDDSQDEEEEEEEDEEDDQEDDEGEEGDEDDDDDGSEMELDEDY 2471



 Score = 35.4 bits (80), Expect = 0.066
 Identities = 17/56 (30%), Positives = 32/56 (57%), Gaps = 1/56 (1%)

Query: 16   QPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDY 71
            Q  D     ++E++ + E E+E++D+ D ++D+E E  DE+ + +     L D DY
Sbjct: 2417 QEEDSSGSNEDEDDSQDEEEEEEEDEEDDQEDDEGEEGDEDDDDDGSEMEL-DEDY 2471


>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
           sapiens]
          Length = 2168

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 18/49 (36%), Positives = 33/49 (67%)

Query: 25  DEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDG 73
           D    K+ E+ +ED+++ D+E+DEED+  DE  + + E+ S S++D +G
Sbjct: 597 DIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEG 645



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 8/76 (10%)

Query: 8   RAVESGVPQPPDPPVQRDEEEEKEVENEDEDD-----DDSDKEKD---EEDEVIDEEVNI 59
           R  +S +P   D     ++EEE + E ++EDD     DDS  E D   E D    EE + 
Sbjct: 592 RGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDD 651

Query: 60  EFEAYSLSDNDYDGIK 75
           + +    SD+D +G K
Sbjct: 652 DDKDQDESDSDTEGEK 667



 Score = 32.7 bits (73), Expect = 0.43
 Identities = 19/56 (33%), Positives = 30/56 (53%), Gaps = 5/56 (8%)

Query: 4    RSKRRAVESGVPQPP---DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEE 56
            R     ++ G  Q P     P ++   +  + + +D+DDDDSD + DE+DE  DEE
Sbjct: 1266 RDTSGGIDLGEEQHPLGTPTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDE--DEE 1319



 Score = 31.6 bits (70), Expect = 0.96
 Identities = 19/63 (30%), Positives = 31/63 (49%), Gaps = 6/63 (9%)

Query: 13  GVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYD 72
           G+       ++ DEEEE +   E+ +DDDSD E + +      + N +   + +SD   D
Sbjct: 259 GISSSDSDDLEEDEEEEDQ-SIEESEDDDSDSESEAQ-----HKSNNQVLLHGISDPKAD 312

Query: 73  GIK 75
           G K
Sbjct: 313 GQK 315



 Score = 28.5 bits (62), Expect = 8.1
 Identities = 13/44 (29%), Positives = 25/44 (56%), Gaps = 2/44 (4%)

Query: 13   GVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEE 56
            G P P     +R +  + + +++D+DD D   ++D+EDE   E+
Sbjct: 1282 GTPTPGRK--RRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKED 1323


>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
          Length = 1390

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 16/33 (48%), Positives = 25/33 (75%)

Query: 26  EEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVN 58
           E+E+ E +++D+DDDD D ++D+EDE   EE N
Sbjct: 258 EDEDDEDDDDDDDDDDDDDDEDDEDEEDGEEEN 290



 Score = 37.7 bits (86), Expect = 0.013
 Identities = 14/32 (43%), Positives = 24/32 (75%)

Query: 25  DEEEEKEVENEDEDDDDSDKEKDEEDEVIDEE 56
           D+E E + E+ED++DDD D + D++D+  D+E
Sbjct: 250 DQEHEDDGEDEDDEDDDDDDDDDDDDDDEDDE 281



 Score = 37.4 bits (85), Expect = 0.017
 Identities = 14/34 (41%), Positives = 24/34 (70%)

Query: 23  QRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEE 56
           +  E++E E + EDEDD+D D + D++D+  DE+
Sbjct: 246 EEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDED 279



 Score = 37.0 bits (84), Expect = 0.023
 Identities = 15/46 (32%), Positives = 28/46 (60%)

Query: 11  ESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEE 56
           E  V    +   Q  E++ ++ ++ED+DDDD D + D++++  DEE
Sbjct: 239 EGSVESSEEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDEDDEDEE 284



 Score = 37.0 bits (84), Expect = 0.023
 Identities = 13/32 (40%), Positives = 26/32 (81%)

Query: 25  DEEEEKEVENEDEDDDDSDKEKDEEDEVIDEE 56
           ++E++++ +++D+DDDD D E DE++E  +EE
Sbjct: 258 EDEDDEDDDDDDDDDDDDDDEDDEDEEDGEEE 289



 Score = 35.8 bits (81), Expect = 0.051
 Identities = 15/52 (28%), Positives = 32/52 (61%)

Query: 11  ESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62
           + G  +  +    ++ E++ E E++++DDDD D + D++DE  ++E + E E
Sbjct: 238 QEGSVESSEEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDEDDEDEEDGEEE 289



 Score = 35.0 bits (79), Expect = 0.086
 Identities = 15/45 (33%), Positives = 29/45 (64%)

Query: 25  DEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDN 69
           +E E++E E++ ED+DD D + D++D+  D++ + E E     +N
Sbjct: 246 EEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDEDDEDEEDGEEEN 290



 Score = 28.5 bits (62), Expect = 8.1
 Identities = 21/85 (24%), Positives = 41/85 (48%), Gaps = 6/85 (7%)

Query: 1   MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
           M +R K++ +     Q  D     ++E   E   E ED +  D  +DE+DE  D++ + +
Sbjct: 218 MYTRGKQKDI-----QRTDEETTDNQEGSVESSEEGEDQEHEDDGEDEDDEDDDDDDDDD 272

Query: 61  FEAYSLSDND-YDGIKKLLQQLFLK 84
            +     D D  DG ++  ++ +L+
Sbjct: 273 DDDDDEDDEDEEDGEEENQKRYYLR 297


>gi|58331272 zinc finger, CCHC domain containing 6 [Homo sapiens]
          Length = 1495

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 39/179 (21%), Positives = 79/179 (44%), Gaps = 20/179 (11%)

Query: 25   DEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKKLLQQLFLK 84
            +EEE+ E E E+E+   +  ++++ED + +E+   E +       D D + +   +L   
Sbjct: 846  EEEEDDEEEEEEEEPRLTINQREDEDGMANED---ELDNTYTGSGDEDALSEEDDELGEA 902

Query: 85   APVNTAELTD------LLIQQNHIGSVIKQTDVSEDSNDDMDEDEVFGFISLLNLTERKG 138
            A     +         LL++ N I   +K+ +V E+ N  +D+ + F   S L  T+ K 
Sbjct: 903  AKYEDVKECGKHVERALLVELNKIS--LKEENVCEEKNSPVDQSDFFYEFSKLIFTKGKS 960

Query: 139  TQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLLSERFINVPPQIALPMYQ 197
               V  + +      E + +K   E   +   +   P    L+ +F+N+  Q+ +  Y+
Sbjct: 961  PTVVCSLCKR-----EGHLKKDCPEDFKRIQLEPLPP----LTPKFLNILDQVCIQCYK 1010


>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
          Length = 740

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 23/59 (38%), Positives = 35/59 (59%), Gaps = 4/59 (6%)

Query: 23  QRDEEEEKEVENEDEDDDDSDKEKD----EEDEVIDEEVNIEFEAYSLSDNDYDGIKKL 77
           + DEEEE+E E E+E+  DS++E+D    +E +  DEE + E EA +  D D   +  L
Sbjct: 442 ESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSL 500



 Score = 34.3 bits (77), Expect = 0.15
 Identities = 13/24 (54%), Positives = 21/24 (87%)

Query: 33  ENEDEDDDDSDKEKDEEDEVIDEE 56
           E +DEDD++SD+E++EE+E  +EE
Sbjct: 434 ETDDEDDEESDEEEEEEEEEEEEE 457



 Score = 33.9 bits (76), Expect = 0.19
 Identities = 14/49 (28%), Positives = 30/49 (61%)

Query: 12  SGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
           SG+     P   R E ++++ E  DE++++ ++E++EE    +EE ++E
Sbjct: 420 SGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLE 468


>gi|215422388 death-domain associated protein isoform a [Homo
           sapiens]
          Length = 740

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 23/59 (38%), Positives = 35/59 (59%), Gaps = 4/59 (6%)

Query: 23  QRDEEEEKEVENEDEDDDDSDKEKD----EEDEVIDEEVNIEFEAYSLSDNDYDGIKKL 77
           + DEEEE+E E E+E+  DS++E+D    +E +  DEE + E EA +  D D   +  L
Sbjct: 442 ESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSL 500



 Score = 34.3 bits (77), Expect = 0.15
 Identities = 13/24 (54%), Positives = 21/24 (87%)

Query: 33  ENEDEDDDDSDKEKDEEDEVIDEE 56
           E +DEDD++SD+E++EE+E  +EE
Sbjct: 434 ETDDEDDEESDEEEEEEEEEEEEE 457



 Score = 33.9 bits (76), Expect = 0.19
 Identities = 14/49 (28%), Positives = 30/49 (61%)

Query: 12  SGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
           SG+     P   R E ++++ E  DE++++ ++E++EE    +EE ++E
Sbjct: 420 SGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLE 468


>gi|215422366 death-domain associated protein isoform b [Homo
           sapiens]
          Length = 752

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 23/59 (38%), Positives = 35/59 (59%), Gaps = 4/59 (6%)

Query: 23  QRDEEEEKEVENEDEDDDDSDKEKD----EEDEVIDEEVNIEFEAYSLSDNDYDGIKKL 77
           + DEEEE+E E E+E+  DS++E+D    +E +  DEE + E EA +  D D   +  L
Sbjct: 454 ESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSL 512



 Score = 34.3 bits (77), Expect = 0.15
 Identities = 13/24 (54%), Positives = 21/24 (87%)

Query: 33  ENEDEDDDDSDKEKDEEDEVIDEE 56
           E +DEDD++SD+E++EE+E  +EE
Sbjct: 446 ETDDEDDEESDEEEEEEEEEEEEE 469



 Score = 33.9 bits (76), Expect = 0.19
 Identities = 14/49 (28%), Positives = 30/49 (61%)

Query: 12  SGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60
           SG+     P   R E ++++ E  DE++++ ++E++EE    +EE ++E
Sbjct: 432 SGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLE 480


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.132    0.370 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,763,290
Number of Sequences: 37866
Number of extensions: 644230
Number of successful extensions: 17356
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 459
Number of HSP's successfully gapped in prelim test: 193
Number of HSP's that attempted gapping in prelim test: 7119
Number of HSP's gapped (non-prelim): 5012
length of query: 314
length of database: 18,247,518
effective HSP length: 102
effective length of query: 212
effective length of database: 14,385,186
effective search space: 3049659432
effective search space used: 3049659432
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.