Guide to the Human Genome
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Search of human proteins with 17149839

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|17149839 FK506 binding protein 1B, 12.6 kDa isoform b [Homo
sapiens]
         (80 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|17149839 FK506 binding protein 1B, 12.6 kDa isoform b [Homo s...   172   4e-44
gi|4758380 FK506 binding protein 1B, 12.6 kDa isoform a [Homo sa...   140   3e-34
gi|17149836 FK506 binding protein 1A, 12kDa [Homo sapiens]            127   1e-30
gi|4503725 FK506 binding protein 1A, 12kDa [Homo sapiens]             127   1e-30
gi|224809331 FK506 binding protein 5 isoform 2 [Homo sapiens]          65   2e-11
gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens]          65   2e-11
gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens]          65   2e-11
gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens]            65   2e-11
gi|4503729 FK506 binding protein 52 [Homo sapiens]                     54   4e-08
gi|206725530 FK506 binding protein 2, 13kDa precursor [Homo sapi...    53   5e-08
gi|17149844 FK506 binding protein 2, 13kDa precursor [Homo sapiens]    53   5e-08
gi|17149842 FK506 binding protein 2, 13kDa precursor [Homo sapiens]    53   5e-08
gi|4503727 FK506 binding protein 3, 25kDa [Homo sapiens]               46   7e-06
gi|33469985 FK506 binding protein 9 [Homo sapiens]                     40   3e-04
gi|192448443 FK506 binding protein 10 [Homo sapiens]                   40   5e-04
gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]           37   0.004
gi|219842220 FK506 binding protein 11 isoform 3 precursor [Homo ...    36   0.006
gi|7706131 FK506 binding protein 11 isoform 1 precursor [Homo sa...    36   0.006
gi|239047795 pleckstrin homology domain containing, family A mem...    28   2.1  
gi|52630440 FK506-binding protein 8 [Homo sapiens]                     27   2.7  
gi|164419749 SWI/SNF-related matrix-associated actin-dependent r...    27   3.5  
gi|21071044 SWI/SNF-related matrix-associated actin-dependent re...    27   3.5  
gi|21071058 SWI/SNF-related matrix-associated actin-dependent re...    26   7.8  

>gi|17149839 FK506 binding protein 1B, 12.6 kDa isoform b [Homo
          sapiens]
          Length = 80

 Score =  172 bits (437), Expect = 4e-44
 Identities = 80/80 (100%), Positives = 80/80 (100%)

Query: 1  MGVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGF 60
          MGVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGF
Sbjct: 1  MGVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGF 60

Query: 61 EEGAAQLGPLSPLPICPHPC 80
          EEGAAQLGPLSPLPICPHPC
Sbjct: 61 EEGAAQLGPLSPLPICPHPC 80


>gi|4758380 FK506 binding protein 1B, 12.6 kDa isoform a [Homo
          sapiens]
          Length = 108

 Score =  140 bits (352), Expect = 3e-34
 Identities = 66/67 (98%), Positives = 67/67 (100%)

Query: 1  MGVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGF 60
          MGVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGF
Sbjct: 1  MGVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGF 60

Query: 61 EEGAAQL 67
          EEGAAQ+
Sbjct: 61 EEGAAQM 67


>gi|17149836 FK506 binding protein 1A, 12kDa [Homo sapiens]
          Length = 108

 Score =  127 bits (320), Expect = 1e-30
 Identities = 60/79 (75%), Positives = 70/79 (88%), Gaps = 2/79 (2%)

Query: 1  MGVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGF 60
          MGV++ETISPGDGRTFPK+GQTCVVHYTGML++GKKFDSSRDRNKPFKF +GKQEVI+G+
Sbjct: 1  MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGW 60

Query: 61 EEGAAQL--GPLSPLPICP 77
          EEG AQ+  G  + L I P
Sbjct: 61 EEGVAQMSVGQRAKLTISP 79


>gi|4503725 FK506 binding protein 1A, 12kDa [Homo sapiens]
          Length = 108

 Score =  127 bits (320), Expect = 1e-30
 Identities = 60/79 (75%), Positives = 70/79 (88%), Gaps = 2/79 (2%)

Query: 1  MGVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGF 60
          MGV++ETISPGDGRTFPK+GQTCVVHYTGML++GKKFDSSRDRNKPFKF +GKQEVI+G+
Sbjct: 1  MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGW 60

Query: 61 EEGAAQL--GPLSPLPICP 77
          EEG AQ+  G  + L I P
Sbjct: 61 EEGVAQMSVGQRAKLTISP 79


>gi|224809331 FK506 binding protein 5 isoform 2 [Homo sapiens]
          Length = 268

 Score = 64.7 bits (156), Expect = 2e-11
 Identities = 30/57 (52%), Positives = 37/57 (64%)

Query: 11 GDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGAAQL 67
          G+G   P  G    VHY G L NGKKFDSS DRN+PF F +GK +VIK ++ G A +
Sbjct: 41 GNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATM 97


>gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens]
          Length = 457

 Score = 64.7 bits (156), Expect = 2e-11
 Identities = 30/57 (52%), Positives = 37/57 (64%)

Query: 11 GDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGAAQL 67
          G+G   P  G    VHY G L NGKKFDSS DRN+PF F +GK +VIK ++ G A +
Sbjct: 41 GNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATM 97


>gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens]
          Length = 457

 Score = 64.7 bits (156), Expect = 2e-11
 Identities = 30/57 (52%), Positives = 37/57 (64%)

Query: 11 GDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGAAQL 67
          G+G   P  G    VHY G L NGKKFDSS DRN+PF F +GK +VIK ++ G A +
Sbjct: 41 GNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATM 97


>gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens]
          Length = 457

 Score = 64.7 bits (156), Expect = 2e-11
 Identities = 30/57 (52%), Positives = 37/57 (64%)

Query: 11 GDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGAAQL 67
          G+G   P  G    VHY G L NGKKFDSS DRN+PF F +GK +VIK ++ G A +
Sbjct: 41 GNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATM 97


>gi|4503729 FK506 binding protein 52 [Homo sapiens]
          Length = 459

 Score = 53.5 bits (127), Expect = 4e-08
 Identities = 27/57 (47%), Positives = 32/57 (56%)

Query: 11 GDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGAAQL 67
          G G   P  G    VHYTG L +G KFDSS DR   F F +GK EVIK ++   A +
Sbjct: 41 GTGTEMPMIGDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATM 97


>gi|206725530 FK506 binding protein 2, 13kDa precursor [Homo
          sapiens]
          Length = 142

 Score = 53.1 bits (126), Expect = 5e-08
 Identities = 22/46 (47%), Positives = 34/46 (73%)

Query: 18 KKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEG 63
          +KG    +HYTG L++G +FDSS  +N+PF F +G  +VIKG+++G
Sbjct: 47 RKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQG 92


>gi|17149844 FK506 binding protein 2, 13kDa precursor [Homo
          sapiens]
          Length = 142

 Score = 53.1 bits (126), Expect = 5e-08
 Identities = 22/46 (47%), Positives = 34/46 (73%)

Query: 18 KKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEG 63
          +KG    +HYTG L++G +FDSS  +N+PF F +G  +VIKG+++G
Sbjct: 47 RKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQG 92


>gi|17149842 FK506 binding protein 2, 13kDa precursor [Homo
          sapiens]
          Length = 142

 Score = 53.1 bits (126), Expect = 5e-08
 Identities = 22/46 (47%), Positives = 34/46 (73%)

Query: 18 KKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEG 63
          +KG    +HYTG L++G +FDSS  +N+PF F +G  +VIKG+++G
Sbjct: 47 RKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQG 92


>gi|4503727 FK506 binding protein 3, 25kDa [Homo sapiens]
          Length = 224

 Score = 45.8 bits (107), Expect = 7e-06
 Identities = 23/62 (37%), Positives = 34/62 (54%), Gaps = 7/62 (11%)

Query: 8   ISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSS-------RDRNKPFKFRIGKQEVIKGF 60
           +  GD   FPKKG      YTG LQ+G  FD++       +   KP  F++G  +VI+G+
Sbjct: 116 LKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGW 175

Query: 61  EE 62
           +E
Sbjct: 176 DE 177


>gi|33469985 FK506 binding protein 9 [Homo sapiens]
          Length = 570

 Score = 40.4 bits (93), Expect = 3e-04
 Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 2/73 (2%)

Query: 8   ISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEG--AA 65
           + P +     + G     HY G L +G  FDSS  RN+ F   IG+  VI G +EG    
Sbjct: 266 VVPENCERISQSGDFLRYHYNGTLLDGTLFDSSYSRNRTFDTYIGQGYVIPGMDEGLLGV 325

Query: 66  QLGPLSPLPICPH 78
            +G    + + PH
Sbjct: 326 CIGEKRRIVVPPH 338



 Score = 40.0 bits (92), Expect = 4e-04
 Identities = 17/45 (37%), Positives = 26/45 (57%)

Query: 18 KKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEE 62
          + G     HY G   +G+KFDSS DR+  F   +GK ++I G ++
Sbjct: 52 RSGDFVRYHYVGTFPDGQKFDSSYDRDSTFNVFVGKGQLITGMDQ 96



 Score = 33.9 bits (76), Expect = 0.029
 Identities = 20/71 (28%), Positives = 31/71 (43%), Gaps = 2/71 (2%)

Query: 10  PGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGAAQL-- 67
           P D     KKG     HY   L +G   DS+ +  K +   +G  +V+ G + G  ++  
Sbjct: 379 PPDCSVLSKKGDYLKYHYNASLLDGTLLDSTWNLGKTYNIVLGSGQVVLGMDMGLREMCV 438

Query: 68  GPLSPLPICPH 78
           G    + I PH
Sbjct: 439 GEKRTVIIPPH 449



 Score = 30.8 bits (68), Expect = 0.24
 Identities = 14/38 (36%), Positives = 21/38 (55%)

Query: 26  HYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEG 63
           HY G   +G  FDSS +R K +   +G   +I G ++G
Sbjct: 172 HYNGTFLDGTLFDSSHNRMKTYDTYVGIGWLIPGMDKG 209


>gi|192448443 FK506 binding protein 10 [Homo sapiens]
          Length = 582

 Score = 39.7 bits (91), Expect = 5e-04
 Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 5/80 (6%)

Query: 3   VEIETIS--PGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGF 60
           V++ET+   PG  R     G     HY G L +G  FDSS  RN  +   IG+  +I G 
Sbjct: 268 VQLETLELPPGCVRR-AGAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYIGQGYIIPGM 326

Query: 61  EEG--AAQLGPLSPLPICPH 78
           ++G   A +G    + I PH
Sbjct: 327 DQGLQGACMGERRRITIPPH 346



 Score = 38.5 bits (88), Expect = 0.001
 Identities = 17/38 (44%), Positives = 22/38 (57%)

Query: 26  HYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEG 63
           HY G  ++GKKFDSS DRN      +G   +I G + G
Sbjct: 68  HYNGTFEDGKKFDSSYDRNTLVAIVVGVGRLITGMDRG 105



 Score = 32.3 bits (72), Expect = 0.084
 Identities = 14/44 (31%), Positives = 23/44 (52%)

Query: 26  HYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGAAQLGP 69
           HY G L +G  FD+S  +   +   +G   +IKG ++G   + P
Sbjct: 180 HYNGTLLDGTSFDTSYSKGGTYDTYVGSGWLIKGMDQGLLGMCP 223



 Score = 29.3 bits (64), Expect = 0.71
 Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 4/80 (5%)

Query: 3   VEIETIS-PGDG-RTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGF 60
           VEI T+S P +      K G     HY   L +G +  +S D   P +  +G  +VI+G 
Sbjct: 380 VEIRTLSRPSETCNETTKLGDFVRYHYNCSLLDGTQLFTSHDYGAPQEATLGANKVIEGL 439

Query: 61  EEGAAQL--GPLSPLPICPH 78
           + G   +  G    L + PH
Sbjct: 440 DTGLQGMCVGERRQLIVPPH 459


>gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]
          Length = 1219

 Score = 36.6 bits (83), Expect = 0.004
 Identities = 20/48 (41%), Positives = 32/48 (66%), Gaps = 4/48 (8%)

Query: 20  GQTCVVHYTGML-QN---GKKFDSSRDRNKPFKFRIGKQEVIKGFEEG 63
           G +  V YTG L QN   G+ FDS+ +++K  + ++G  +VIKG+E+G
Sbjct: 197 GDSLEVAYTGWLFQNHVLGQVFDSTANKDKLLRLKLGSGKVIKGWEDG 244


>gi|219842220 FK506 binding protein 11 isoform 3 precursor [Homo
          sapiens]
          Length = 146

 Score = 36.2 bits (82), Expect = 0.006
 Identities = 17/43 (39%), Positives = 27/43 (62%), Gaps = 1/43 (2%)

Query: 20 GQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEE 62
          G T  +HYTG L +G+  D+S  R+ P    +G+++VI G E+
Sbjct: 57 GDTLHIHYTGSLVDGRIIDTSLTRD-PLVIELGQKQVIPGLEQ 98


>gi|7706131 FK506 binding protein 11 isoform 1 precursor [Homo
          sapiens]
          Length = 201

 Score = 36.2 bits (82), Expect = 0.006
 Identities = 17/43 (39%), Positives = 27/43 (62%), Gaps = 1/43 (2%)

Query: 20 GQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEE 62
          G T  +HYTG L +G+  D+S  R+ P    +G+++VI G E+
Sbjct: 57 GDTLHIHYTGSLVDGRIIDTSLTRD-PLVIELGQKQVIPGLEQ 98


>gi|239047795 pleckstrin homology domain containing, family A member
           7 [Homo sapiens]
          Length = 1121

 Score = 27.7 bits (60), Expect = 2.1
 Identities = 12/39 (30%), Positives = 20/39 (51%)

Query: 4   EIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRD 42
           E   + PG  R  P +G   +V++    Q G+++ S RD
Sbjct: 312 ECGRVGPGHTRDCPHRGHDDIVNFERQEQEGEQYRSQRD 350


>gi|52630440 FK506-binding protein 8 [Homo sapiens]
          Length = 413

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 17/57 (29%), Positives = 27/57 (47%), Gaps = 5/57 (8%)

Query: 6   ETISPGD-GRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFE 61
           +T+ PG  G + P KGQ   VH    L+NG +     +      F +G  +VI+  +
Sbjct: 105 KTLVPGPPGSSRPVKGQVVTVHLQTSLENGTRVQEEPE----LVFTLGDCDVIQALD 157


>gi|164419749 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a1 isoform b [Homo sapiens]
          Length = 1042

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 13/32 (40%), Positives = 19/32 (59%)

Query: 42  DRNKPFKFRIGKQEVIKGFEEGAAQLGPLSPL 73
           DR K F+F + + E+   F + +AQ  P SPL
Sbjct: 90  DRAKRFEFLLKQTELFAHFIQPSAQKSPTSPL 121


>gi|21071044 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a1 isoform a [Homo sapiens]
          Length = 1054

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 13/32 (40%), Positives = 19/32 (59%)

Query: 42  DRNKPFKFRIGKQEVIKGFEEGAAQLGPLSPL 73
           DR K F+F + + E+   F + +AQ  P SPL
Sbjct: 90  DRAKRFEFLLKQTELFAHFIQPSAQKSPTSPL 121


>gi|21071058 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a5 [Homo sapiens]
          Length = 1052

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 13/36 (36%), Positives = 20/36 (55%)

Query: 42  DRNKPFKFRIGKQEVIKGFEEGAAQLGPLSPLPICP 77
           DR   F++ + + E+   F + AAQ  P SPL + P
Sbjct: 87  DRANRFEYLLKQTELFAHFIQPAAQKTPTSPLKMKP 122


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.141    0.444 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,607,554
Number of Sequences: 37866
Number of extensions: 138089
Number of successful extensions: 314
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 285
Number of HSP's gapped (non-prelim): 29
length of query: 80
length of database: 18,247,518
effective HSP length: 52
effective length of query: 28
effective length of database: 16,278,486
effective search space: 455797608
effective search space used: 455797608
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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