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Search of human proteins with 170650672
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|170650672 Leber congenital amaurosis 5 [Homo sapiens]
(697 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|170650672 Leber congenital amaurosis 5 [Homo sapiens] 1378 0.0
gi|170650670 Leber congenital amaurosis 5 [Homo sapiens] 1378 0.0
gi|22749049 Leber congenital amaurosis 5-like [Homo sapiens] 204 2e-52
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 80 5e-15
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 77 4e-14
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 74 3e-13
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 72 2e-12
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 71 3e-12
gi|118498356 kinectin 1 isoform a [Homo sapiens] 71 4e-12
gi|118498368 kinectin 1 isoform c [Homo sapiens] 71 4e-12
gi|33620775 kinectin 1 isoform a [Homo sapiens] 71 4e-12
gi|148746195 trichohyalin [Homo sapiens] 71 4e-12
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 71 4e-12
gi|118498362 kinectin 1 isoform b [Homo sapiens] 69 1e-11
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 69 1e-11
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 67 6e-11
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 67 7e-11
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 67 7e-11
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 66 1e-10
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens] 66 1e-10
gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens] 65 2e-10
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 65 3e-10
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 64 4e-10
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 63 1e-09
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 63 1e-09
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 62 2e-09
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 62 2e-09
gi|41872583 Rho-associated, coiled-coil containing protein kinas... 62 2e-09
gi|58530840 desmoplakin isoform I [Homo sapiens] 61 3e-09
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 61 3e-09
>gi|170650672 Leber congenital amaurosis 5 [Homo sapiens]
Length = 697
Score = 1378 bits (3566), Expect = 0.0
Identities = 697/697 (100%), Positives = 697/697 (100%)
Query: 1 MGERAGSPGTDQERKAGKHHYSYLSDFETPQSSGRSSLVSSSPASVRRKNPKRQTSDGQV 60
MGERAGSPGTDQERKAGKHHYSYLSDFETPQSSGRSSLVSSSPASVRRKNPKRQTSDGQV
Sbjct: 1 MGERAGSPGTDQERKAGKHHYSYLSDFETPQSSGRSSLVSSSPASVRRKNPKRQTSDGQV 60
Query: 61 HHQAPRKPSPKGLPNRKGVRVGFRSQSLNREPLRKDTDLVTKRILSARLLKINELQNEVS 120
HHQAPRKPSPKGLPNRKGVRVGFRSQSLNREPLRKDTDLVTKRILSARLLKINELQNEVS
Sbjct: 61 HHQAPRKPSPKGLPNRKGVRVGFRSQSLNREPLRKDTDLVTKRILSARLLKINELQNEVS 120
Query: 121 ELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQE 180
ELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQE
Sbjct: 121 ELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQE 180
Query: 181 KERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIK 240
KERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIK
Sbjct: 181 KERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIK 240
Query: 241 ELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSN 300
ELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSN
Sbjct: 241 ELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSN 300
Query: 301 RLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEE 360
RLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEE
Sbjct: 301 RLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEE 360
Query: 361 PGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKK 420
PGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKK
Sbjct: 361 PGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKK 420
Query: 421 QKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQD 480
QKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQD
Sbjct: 421 QKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQD 480
Query: 481 SRNLKYPVLPLLPDFESKLHSPERSPKTYRFSESSERLFNGHHLQDISFSTPKGEGQNSG 540
SRNLKYPVLPLLPDFESKLHSPERSPKTYRFSESSERLFNGHHLQDISFSTPKGEGQNSG
Sbjct: 481 SRNLKYPVLPLLPDFESKLHSPERSPKTYRFSESSERLFNGHHLQDISFSTPKGEGQNSG 540
Query: 541 NVRSPASPNEFAFGSYVPSFAKTSERSNPFSQKSSFLDFQRNSMEKLSKDGVDLITRKEK 600
NVRSPASPNEFAFGSYVPSFAKTSERSNPFSQKSSFLDFQRNSMEKLSKDGVDLITRKEK
Sbjct: 541 NVRSPASPNEFAFGSYVPSFAKTSERSNPFSQKSSFLDFQRNSMEKLSKDGVDLITRKEK 600
Query: 601 KANLMEQLFGASGSSTISSKSSDPNSVASSKGDIDPLNFLPGNKGSRDQEHDEDEGFFLS 660
KANLMEQLFGASGSSTISSKSSDPNSVASSKGDIDPLNFLPGNKGSRDQEHDEDEGFFLS
Sbjct: 601 KANLMEQLFGASGSSTISSKSSDPNSVASSKGDIDPLNFLPGNKGSRDQEHDEDEGFFLS 660
Query: 661 EGRSFNPNRHRLKHADDKPAVKAADSVEDEIEEVALR 697
EGRSFNPNRHRLKHADDKPAVKAADSVEDEIEEVALR
Sbjct: 661 EGRSFNPNRHRLKHADDKPAVKAADSVEDEIEEVALR 697
>gi|170650670 Leber congenital amaurosis 5 [Homo sapiens]
Length = 697
Score = 1378 bits (3566), Expect = 0.0
Identities = 697/697 (100%), Positives = 697/697 (100%)
Query: 1 MGERAGSPGTDQERKAGKHHYSYLSDFETPQSSGRSSLVSSSPASVRRKNPKRQTSDGQV 60
MGERAGSPGTDQERKAGKHHYSYLSDFETPQSSGRSSLVSSSPASVRRKNPKRQTSDGQV
Sbjct: 1 MGERAGSPGTDQERKAGKHHYSYLSDFETPQSSGRSSLVSSSPASVRRKNPKRQTSDGQV 60
Query: 61 HHQAPRKPSPKGLPNRKGVRVGFRSQSLNREPLRKDTDLVTKRILSARLLKINELQNEVS 120
HHQAPRKPSPKGLPNRKGVRVGFRSQSLNREPLRKDTDLVTKRILSARLLKINELQNEVS
Sbjct: 61 HHQAPRKPSPKGLPNRKGVRVGFRSQSLNREPLRKDTDLVTKRILSARLLKINELQNEVS 120
Query: 121 ELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQE 180
ELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQE
Sbjct: 121 ELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQE 180
Query: 181 KERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIK 240
KERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIK
Sbjct: 181 KERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIK 240
Query: 241 ELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSN 300
ELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSN
Sbjct: 241 ELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSN 300
Query: 301 RLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEE 360
RLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEE
Sbjct: 301 RLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEE 360
Query: 361 PGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKK 420
PGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKK
Sbjct: 361 PGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKK 420
Query: 421 QKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQD 480
QKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQD
Sbjct: 421 QKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQD 480
Query: 481 SRNLKYPVLPLLPDFESKLHSPERSPKTYRFSESSERLFNGHHLQDISFSTPKGEGQNSG 540
SRNLKYPVLPLLPDFESKLHSPERSPKTYRFSESSERLFNGHHLQDISFSTPKGEGQNSG
Sbjct: 481 SRNLKYPVLPLLPDFESKLHSPERSPKTYRFSESSERLFNGHHLQDISFSTPKGEGQNSG 540
Query: 541 NVRSPASPNEFAFGSYVPSFAKTSERSNPFSQKSSFLDFQRNSMEKLSKDGVDLITRKEK 600
NVRSPASPNEFAFGSYVPSFAKTSERSNPFSQKSSFLDFQRNSMEKLSKDGVDLITRKEK
Sbjct: 541 NVRSPASPNEFAFGSYVPSFAKTSERSNPFSQKSSFLDFQRNSMEKLSKDGVDLITRKEK 600
Query: 601 KANLMEQLFGASGSSTISSKSSDPNSVASSKGDIDPLNFLPGNKGSRDQEHDEDEGFFLS 660
KANLMEQLFGASGSSTISSKSSDPNSVASSKGDIDPLNFLPGNKGSRDQEHDEDEGFFLS
Sbjct: 601 KANLMEQLFGASGSSTISSKSSDPNSVASSKGDIDPLNFLPGNKGSRDQEHDEDEGFFLS 660
Query: 661 EGRSFNPNRHRLKHADDKPAVKAADSVEDEIEEVALR 697
EGRSFNPNRHRLKHADDKPAVKAADSVEDEIEEVALR
Sbjct: 661 EGRSFNPNRHRLKHADDKPAVKAADSVEDEIEEVALR 697
>gi|22749049 Leber congenital amaurosis 5-like [Homo sapiens]
Length = 670
Score = 204 bits (519), Expect = 2e-52
Identities = 165/546 (30%), Positives = 278/546 (50%), Gaps = 62/546 (11%)
Query: 98 DLVTKRILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEI 157
D + RILSARL KI L+NE++++ KL +L EN+ LK+LQ R KA+ K+E+++N +
Sbjct: 137 DAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNL 196
Query: 158 SQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPE 217
Q++ +H NE+ L++ LRKSQEKER +++++T+S+L +TK LQ L+++SE ++L E
Sbjct: 197 PQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLRETDSQLLKTKDILQALQKLSEDKNLAE 256
Query: 218 RDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKE 277
R++L KL K+D +++I+ L K L L+ +F RQL E ++ A K LQ E
Sbjct: 257 REELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVE 316
Query: 278 VQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTME 337
V+ L KLKEK+REL+IKNIYS+R+ K+ + E + + Q+D L ++
Sbjct: 317 VKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQG 376
Query: 338 DFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQD-RHGEAGILNPIMEREE-----K 391
K + PLT + N +D + + + H +N + ++E+ +
Sbjct: 377 TQKSDVPPLTTKGKKATGN---------IDHKEKSTEINHEIPHCVNKLPKQEDSKRKYE 427
Query: 392 FVTDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNM 451
++ EE H+ EV+ L + R++ K+ +EK ++ +EE+ E ++ ++P +
Sbjct: 428 DLSGEEKHL---EVQILLENTGRQKDKKEDQEKKNIFVKEEQ-ELPPKIIEV-IHPERES 482
Query: 452 DKLQGEEEERLKREMLLAKLNEIDRELQDSRNLKYPVLPLLPDFESKLHSPERSPKTYRF 511
++ E+ KR M + N +D L Y PL R + Y F
Sbjct: 483 NQEDVLVREKFKRSM---QRNGVDDTLGKG-TAPYTKGPL------------RQRRHYSF 526
Query: 512 SESSERLFNGHHLQDISFSTPKGEGQNSGNVRSPASPNEFAFGSYVPSFAKTSERSNPFS 571
+E++E L +G G N+GN+R Y S K
Sbjct: 527 TEATENLHHG--------LPASGGPANAGNMR------------YSHSTGKHLSNREEME 566
Query: 572 QKSSFLDFQRNSMEKLSKDGVDLITRKEKKANLMEQLFGASGSSTISSKSSDPNSVASSK 631
+ S ++ S K S+ V T ++KK++LME+LFG+ +D +S +K
Sbjct: 567 LEHSDSGYEP-SFGKSSRIKVKDTTFRDKKSSLMEELFGSG-----YVLKTDQSSPGVAK 620
Query: 632 GDIDPL 637
G +PL
Sbjct: 621 GSEEPL 626
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 80.5 bits (197), Expect = 5e-15
Identities = 93/457 (20%), Positives = 213/457 (46%), Gaps = 40/457 (8%)
Query: 83 FRSQSLNREPLRKDTDLVTKRILSARLLKINELQNEVSELQVKL--AELLK---ENKSLK 137
+R+ N E +K+ +L K L+ + +E+Q V EL+ KL A+ L + +L+
Sbjct: 176 YRNTITNEELKKKNAELQEKLRLAES--EKSEIQLNVKELKRKLERAKFLLPQVQTNTLQ 233
Query: 138 RLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELF 197
+RQE+ L + E + + ++R + + ++R+ +EK R EKR+++ E EL
Sbjct: 234 EEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKEL- 292
Query: 198 RTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQL 257
++ KE+ E + L E+++ ++ E K+ + E +++E + + Q
Sbjct: 293 -----REQEKELREQKKLREQEE---QMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE 344
Query: 258 LAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRK 317
R++ + D+ + + ++ +RL K +E+ RE + ++ + +E+E +R+
Sbjct: 345 KQMREQEQKMRDQEERMWEQDERLREK-EERMREQEKMWEQEEKMQEEERIREREKKMRE 403
Query: 318 NAACQSDFADLCTKGVQTM-----EDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQK 372
+ + K + M ++++ + P E + + K +E + + +
Sbjct: 404 EEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLW-EQEKMQEQEEKIWEQEEKI 462
Query: 373 QDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDE----WERE----ELDKKQKEK 424
+D+ G M R+EK + ++E + +QE EK+ D+ W++E E D++ +EK
Sbjct: 463 RDQEEMWG-QEKKMWRQEK-MREQEDQMWEQE-EKMRDQEQKMWDQEERMWEQDERLREK 519
Query: 425 ASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQDSRNL 484
+ RE+K W+ Q +K ++EE+++ E ++ E ++++++ +
Sbjct: 520 EERM-REQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREE---ERMREREKKMREEEEM 575
Query: 485 KYPVLPLLPDFESKLHSPERS--PKTYRFSESSERLF 519
+ + E K+ E + + E E+++
Sbjct: 576 MREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMW 612
Score = 65.5 bits (158), Expect = 2e-10
Identities = 74/401 (18%), Positives = 190/401 (47%), Gaps = 40/401 (9%)
Query: 111 KINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITA 170
++ E + E+ E + +L E K + +++Q ++EK + E+ E + ++R +
Sbjct: 284 RLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQ-EEKMREQEEKMWRQEERLWE 342
Query: 171 LKERLRKSQEKERATEKRV-------KDTESELFRTKFSLQKLKEISEARHLPERDDLAK 223
++++R+ ++K R E+R+ ++ E + + ++ +++ E + ER+ K
Sbjct: 343 QEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRERE---K 399
Query: 224 KLVSAELKLDDTERRIKELSKNL-ELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLY 282
K+ E + + E ++++ +N+ E +Q+Q L E+K E E + +Q++ ++++
Sbjct: 400 KMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQK---EKLWEQEKMQEQEEKIW 456
Query: 283 HKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPE 342
+ +EK R+ + ++ + +E+E + + D + M + + E
Sbjct: 457 EQ-EEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWE-QDE 514
Query: 343 EYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVK 402
E + + W++ + + ++Q+Q++ ++EEK +E + +
Sbjct: 515 RLREKEERMREQKKMWQQEEKMREEKKTQEQEKK--------TWDQEEKMREEERMRERE 566
Query: 403 QEVEKLEDEWEREELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERL 462
+++ + E+E RE+ +K Q+++ + E+EEK WE +K+Q +EE+
Sbjct: 567 KKMRE-EEEMMREQEEKMQEQEEKMREQEEK-MWE------------QEEKMQEQEEKMW 612
Query: 463 KREMLLAKLNEIDRELQDSRNLKYPVLPLLPDFESKLHSPE 503
++E + + E D+ +Q+ + + + + E K+ E
Sbjct: 613 EQEEKMWEQEEEDK-MQEQEEMMWEQEEKMQEQEEKMWEQE 652
Score = 62.8 bits (151), Expect = 1e-09
Identities = 72/391 (18%), Positives = 172/391 (43%), Gaps = 26/391 (6%)
Query: 114 ELQNEVSELQVKLAELLKENKSLKRLQYRQEKAL-NKFEDAENEISQLIFRHNNEITALK 172
E E ++ + ++ +E ++++ + + +K N +E E E Q E +
Sbjct: 386 EKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQ 445
Query: 173 ERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKL 232
E++++ +EK E++++D E + K ++ K + + E+++ K+ E K+
Sbjct: 446 EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEE---KMRDQEQKM 502
Query: 233 DDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKEREL 292
D E R+ E + L + + + E+K+ ++ Q+E R K +E+E++
Sbjct: 503 WDQEERMWEQDERLRE-----KEERMREQKKMWQ--------QEEKMREEKKTQEQEKKT 549
Query: 293 DIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIM 352
+ ++ + +E+E +R+ + + + + M + + + + +
Sbjct: 550 WDQE---EKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQE 606
Query: 353 CYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEW 412
E WE+ + + K E + E+EEK EE ++E + ++E
Sbjct: 607 QEEKMWEQEEKMWEQEEEDKMQEQEEM-----MWEQEEKMQEQEEKMWEQEEKMREQEEK 661
Query: 413 EREELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNM-DKLQGEEEERLKREMLLAKL 471
RE+ +K Q ++ + E+EEK + + + + ++ +K+ G+EE+ +E +
Sbjct: 662 MREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQ 721
Query: 472 NEIDRELQDSRNLKYPVLPLLPDFESKLHSP 502
E+ + + R+ K + LP+ E + P
Sbjct: 722 EEMREKEERIRDQKEKMQERLPEHEERCSEP 752
Score = 62.4 bits (150), Expect = 1e-09
Identities = 82/431 (19%), Positives = 190/431 (44%), Gaps = 53/431 (12%)
Query: 84 RSQSLNREPLRKDTDLVTKRILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQ 143
R + +E ++ +L ++ L + ++ E + ++ E + K+ E ++ + + Q
Sbjct: 284 RLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQ 343
Query: 144 EKALNKFEDAENEISQLIFRHNNEITALKERLR----------KSQEKERATE--KRVKD 191
EK + + E + + ++ + + +ER+R K QE+ER E K++++
Sbjct: 344 EKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMRE 403
Query: 192 TESELFRTKFSLQKLKEIS--------EARHLPERDDLA---KKLVSAELKLDDTERRIK 240
E + + +QK +E + + LPE+ + +K+ E K+ + E +I+
Sbjct: 404 EEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIR 463
Query: 241 ELSKNLELSTNSFQRQLLAERK-RAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYS 299
+ + ++++ + E++ + +E ++ + ++++ ++ E++ L K
Sbjct: 464 DQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKE--- 520
Query: 300 NRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWE 359
R+ + ++E +R+ Q Q + + EE E + E K
Sbjct: 521 ERMREQKKMWQQEEKMREEKKTQE----------QEKKTWDQEEKMREEERMREREKKMR 570
Query: 360 EPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEV--EKLEDEWEREEL 417
E + + + + Q++ + + E+EEK EE ++E E+ E WE+EE
Sbjct: 571 EEEEMMREQEEKMQEQEEK------MREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEE 624
Query: 418 DKKQKEKASLLEREEKPE------WETGRYQLGMYP--IQNMDKLQGEEEERLKREMLLA 469
DK Q+++ + E+EEK + WE + +K+QG+EE+ ++E +
Sbjct: 625 DKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQ 684
Query: 470 KLNEIDRELQD 480
E RE ++
Sbjct: 685 GQEEKMREQEE 695
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 77.4 bits (189), Expect = 4e-14
Identities = 98/485 (20%), Positives = 212/485 (43%), Gaps = 64/485 (13%)
Query: 83 FRSQSLNREPLRKDTDLVTKRILSARLLKINELQNEVSELQVKL--AELLK---ENKSLK 137
+R+ N E +K+ +L K L+ + +E+Q V EL+ KL A+ L + +L+
Sbjct: 214 YRNTITNEELKKKNAELQEKLPLAES--EKSEIQLNVKELKRKLERAKFLLPQVQTNTLQ 271
Query: 138 RLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELF 197
+RQE+ L + E + + ++R + + ++R+ +EK EKR+++ E EL
Sbjct: 272 EEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELR 331
Query: 198 RTKFSLQKLKEISEARHLPERD-----DLAKKLVSAELKLDDTERRIKELSKNL---ELS 249
+ L++ KE+ E + + +K+ E K+ E R+ E K + E
Sbjct: 332 EQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQK 391
Query: 250 TNSFQRQLLAERKRAYEAHD---ENKVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSS 306
+ ++ + +R E + E + + ++V+++ + K +E+E ++ ++ +
Sbjct: 392 MRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRD-QEEKMQEEE 450
Query: 307 PNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEY--PLTPETIMCYENKWEEPGHL 364
+E+E +R+ + + K + M + + +E+ PE E WE+
Sbjct: 451 RIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQ---KEKLWEQE--- 504
Query: 365 TLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEV---EKLEDE----WEREEL 417
+Q Q++ I E+EEK EE+ ++++ EK+ ++ WE+EE
Sbjct: 505 --KMQEQEE----------KIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEK 552
Query: 418 DKKQKEK--------ASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLA 469
+ Q++K + +EK W+ ++ +K EEEE ++ +
Sbjct: 553 MRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE--E 610
Query: 470 KLNEIDRELQDSRNLKYPVLPLLPDFESKL--------HSPERSPKTYRFSESSERLFNG 521
K+ E + ++Q+ + + + E K+ E+ + R E E+L+
Sbjct: 611 KMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEH 670
Query: 522 HHLQD 526
+Q+
Sbjct: 671 EKMQE 675
Score = 69.3 bits (168), Expect = 1e-11
Identities = 81/393 (20%), Positives = 177/393 (45%), Gaps = 42/393 (10%)
Query: 111 KINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITA 170
++ E + ++ E + K+ E ++ + + +RQE+ L + E E Q + +
Sbjct: 342 ELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWE 401
Query: 171 LKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLA---KKLVS 227
ERLR+ +E+ R EK + E K Q+ K + + E + + KK+
Sbjct: 402 QDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMRE 461
Query: 228 AELKLDDTERRIKELSKNL-ELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLK 286
E + + E ++++ +N+ E +Q+Q L E+K E E + +Q++ ++++ + +
Sbjct: 462 EEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQK---EKLWEQEKMQEQEEKIWEQ-E 517
Query: 287 EKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPL 346
EK R+ + ++ + +E+E + + D + ME E+
Sbjct: 518 EKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKK 577
Query: 347 TPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVE 406
T W++ + + + +++++ M EE+ + ++E + +QE +
Sbjct: 578 T----------WDQEEKMREEERMREREKK---------MREEEEMMREQEEKMQEQEEK 618
Query: 407 KLEDE---WEREELDKKQKEKA-----SLLEREEKPEWETGRY-----QLGMY-PIQNMD 452
E E WE+EE ++Q+EK + E+EEK WE R +L + +Q +
Sbjct: 619 MQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKM-WEQQRLPEQKEKLWEHEKMQEQE 677
Query: 453 KLQGEEEERLKREMLLAKLNEIDRELQDSRNLK 485
K+Q +EE+ ++E + K E +++ D ++
Sbjct: 678 KMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMR 710
Score = 56.6 bits (135), Expect = 8e-08
Identities = 68/361 (18%), Positives = 169/361 (46%), Gaps = 31/361 (8%)
Query: 114 ELQNEVSELQVKLAELLKENKSLKRLQYRQEKAL-NKFEDAENEISQLIFRHNNEITALK 172
E E ++ + ++ +E ++++ + + +K N +E E E Q E +
Sbjct: 444 EKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQ 503
Query: 173 ERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKL 232
E++++ +EK E++++D E + K ++ K + + E+++ K+ E K+
Sbjct: 504 EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEE---KMRDQEQKM 560
Query: 233 DDTERRIKELSKNLELSTNSFQRQLLAE---RKRAYEAHDENKVLQKEVQRLYH---KLK 286
D E R+++ ++ E T + ++ E R+R + +E ++++++ +++ K++
Sbjct: 561 WDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQ 620
Query: 287 EKEREL-DIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTK-----GVQTMEDFK 340
E+E ++ + + + K +EK + Q + K +Q E +
Sbjct: 621 EQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQ 680
Query: 341 PEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHV 400
+E + + M E K +E T D + +++ + ERE+K +EE+
Sbjct: 681 EQEEKIWEQEKM--EKKTQEQEKKTWDQEKMREEES--------MREREKKMREEEEM-- 728
Query: 401 VKQEVEKLEDEWER--EELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEE 458
++++ EK++++ E+ E+ ++ +++ + E+EEK WE R + +K+Q +E
Sbjct: 729 MREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKM-WEQQRLPEQKEKLWEHEKMQEQE 787
Query: 459 E 459
+
Sbjct: 788 K 788
Score = 56.6 bits (135), Expect = 8e-08
Identities = 73/371 (19%), Positives = 168/371 (45%), Gaps = 56/371 (15%)
Query: 111 KINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITA 170
K+ E + ++ E + K+ + +E ++ +RQEK + + ED E + + ++
Sbjct: 505 KMQEQEEKIWEQEEKIRDQ-EEMWGQEKKMWRQEK-MREQEDQMWEQEEKMRDQEQKMWD 562
Query: 171 LKERL-RKSQEKERAT---------EKRVKDTESELFRTKFSLQKLKEISEARHLPERDD 220
+ER+ +K+QE+E+ T E+R+++ E ++ R + + + +E + +
Sbjct: 563 QEERMEKKTQEQEKKTWDQEEKMREEERMREREKKM-REEEEMMREQEEKMQEQEEKMQE 621
Query: 221 LAKKLVSAELKLDDTERRIKELSKNL-ELSTNSFQRQLLAERKRAYEAHD---ENKVLQK 276
+K+ E K+ + E ++ E + + E +++Q L E+K H+ E + +Q+
Sbjct: 622 QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQE 681
Query: 277 EVQRLYH--KLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQ 334
+ ++++ K+++K +E + K ++ + +E+E +R+ + + + +
Sbjct: 682 QEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEE 741
Query: 335 TMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVT 394
M++ + E + + E WE+ + E++EK
Sbjct: 742 KMQEQEEEMWEQEEKMWEQEEKMWEQ----------------------QRLPEQKEKLWE 779
Query: 395 DEELHVVKQEVEKLEDEWEREELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMDKL 454
E++ QE EK+ WE+EE + Q+EK E + + + E R Q +K+
Sbjct: 780 HEKM----QEQEKI---WEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQ--------EEKM 824
Query: 455 QGEEEERLKRE 465
G+EE+ +E
Sbjct: 825 WGQEEKMWGQE 835
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 74.3 bits (181), Expect = 3e-13
Identities = 104/443 (23%), Positives = 188/443 (42%), Gaps = 53/443 (11%)
Query: 82 GFRSQSLNRE--PLRKDTDLVTKRILSARLL--KINELQNEVSELQVKLAELLKENKSLK 137
G R++ L E L K+ +L+ K+I + ++ KI L+ E SEL+ + +L K S K
Sbjct: 624 GERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFK 683
Query: 138 RLQYRQEKALNKFEDAENEISQLIFRHNNE---ITALKERLRKSQEKERATEKRVKDTES 194
L ++ E +L K E+++ + L R N E ++K + + KE +EK
Sbjct: 684 NLTFQLE-SLEK-ENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGL 741
Query: 195 ELFRTKFSLQKLKEIS------EARHLPER-DDLAKKLVSAELKLDDTERRIKELSKNLE 247
EL + F + E+S E + L + ++ KK+ E +L D E + L KNLE
Sbjct: 742 ELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLE 801
Query: 248 -LSTNSFQRQLLAERKRAYEAHD-----ENKVLQKEVQRLYHKLKEKERELDIKNIYSNR 301
L +S + + L + ++ E + K L+KE +RL + + K+ L+ N+
Sbjct: 802 ELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGN 861
Query: 302 LPKSSPNKEKELALRKNAACQ--------SDFADLCTKGVQTM----EDFKPEEYPLTPE 349
L K + KE+ + K + + + T ++T+ ED E+ T +
Sbjct: 862 LEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLK-TQQ 920
Query: 350 TIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLE 409
E E + L+ + D ++E + + + L + ++++ LE
Sbjct: 921 MNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALE 980
Query: 410 DEWE---------REELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEE 460
E R+EL +K +L +R+++ R PI D E +
Sbjct: 981 ARLEESTNYNQQLRQELKTVKKNYEALKQRQDEE-----RMVQSSPPISGEDNKWERESQ 1035
Query: 461 RLKREMLLAKLNEIDRELQDSRN 483
RE+L K DR ++ RN
Sbjct: 1036 ETTRELLKVK----DRLIEVERN 1054
Score = 57.8 bits (138), Expect = 3e-08
Identities = 97/412 (23%), Positives = 181/412 (43%), Gaps = 69/412 (16%)
Query: 85 SQSLNREPLRKDTDLVTKRILSARLLKINELQNE-----VSEL--------QVKLAELLK 131
S+ L +E + + + T R S R +KI E +NE VS L + ++ ++ K
Sbjct: 528 SKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEK 587
Query: 132 ENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKD 191
ENK L L+K E + +I + E+ KE+ +++E E E +
Sbjct: 588 ENKILHESIKETSSKLSKIEFEKRQIKK-------ELEHYKEKGERAEELE--NELHHLE 638
Query: 192 TESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTN 251
E+EL + K + K+ +K+ + E + + ER ++L K L+ S
Sbjct: 639 KENELLQKKITNLKI--------------TCEKIEALEQENSELERENRKLKKTLD-SFK 683
Query: 252 SFQRQLLAERKRAYEAHDENKVLQKEVQRL-YHKLKEKERELDIKNIYSNRLPKSSPNKE 310
+ QL + K + +EN L++ V+ L +K + +L+ K + S + +
Sbjct: 684 NLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEK-----EQLK 738
Query: 311 KELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQS 370
K L L K + +++ ++ +G+ D + + T E NK + L+S
Sbjct: 739 KGLELLKASFKKTERLEVSYQGL----DIENQRLQKTLEN----SNKKIQ------QLES 784
Query: 371 QKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLER 430
+ QD E L + EE ++ + L +++E + LE E + E DKKQ EK + R
Sbjct: 785 ELQDLEMENQTLQKNL--EELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLR 842
Query: 431 EEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAK-----LNEIDRE 477
++ E + + I N++K E + L +E+ + K L E+++E
Sbjct: 843 QQ-AEIKDTTLEENNVKIGNLEK----ENKTLSKEIGIYKESCVRLKELEKE 889
Score = 51.6 bits (122), Expect = 2e-06
Identities = 105/462 (22%), Positives = 203/462 (43%), Gaps = 87/462 (18%)
Query: 91 EPLRKDTDLV--TKRILS-------ARLLKINELQNEVSELQVKL--------------A 127
E L++D ++ TK +L AR K++EL+ E +L+ KL
Sbjct: 347 EELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIE 406
Query: 128 ELLKENKSLKRLQYR-QEKALNKFEDAE--------NEISQLIFRHN-NEITALK----- 172
EL++EN +L+ Q + +++L+ + E +E Q H NE+T+ +
Sbjct: 407 ELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLE 466
Query: 173 ---ERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKE---------ISEARHLPERDD 220
+ L K+ E+ R T V+ S++ + + Q+L + + E + L +
Sbjct: 467 MENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQN 526
Query: 221 LAKKLVSAELKLDDT--------ERRIKEL---SKNLELSTNSF-QRQLLAERKRAYEAH 268
L+K L+ + +L+ T ER+IK L +++L + +S QR ++ R +
Sbjct: 527 LSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIE 586
Query: 269 DENKVLQKEVQRLYHKLKEKERE-LDIKNIYSNRLPKSSPNKEKELAL----RKNAACQS 323
ENK+L + ++ KL + E E IK + K +E E L ++N Q
Sbjct: 587 KENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQK 646
Query: 324 DFADL---CTKGVQTMEDFKPE---EYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHG 377
+L C K ++ +E E E +T+ ++N LT L+S +++ +
Sbjct: 647 KITNLKITCEK-IEALEQENSELERENRKLKKTLDSFKN-------LTFQLESLEKE-NS 697
Query: 378 EAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLEREEKPEWE 437
+ N + R + + + + + ++E E E E+E+L K + + ++ E+ E
Sbjct: 698 QLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVS 757
Query: 438 TGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQ 479
YQ G+ I+N + E K + L ++L +++ E Q
Sbjct: 758 ---YQ-GL-DIENQRLQKTLENSNKKIQQLESELQDLEMENQ 794
Score = 43.1 bits (100), Expect = 9e-04
Identities = 62/239 (25%), Positives = 97/239 (40%), Gaps = 33/239 (13%)
Query: 85 SQSLNREPLRKDTDLVTKRILSARLLKINE-LQNEVS---ELQVKLAELLKENKSL-KRL 139
++ L ++ KDT L + L K N+ L E+ E V+L EL KENK L KR
Sbjct: 838 NKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRA 897
Query: 140 QYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRK---SQEKERATEKRVKDTESEL 196
+ + ED +E + + NN++ L L K ++E+ E+ D+ +L
Sbjct: 898 TIDIKTLVTLREDLVSEKLKTQ-QMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKL 956
Query: 197 FRTKF--SLQKLKEISEAR----------------HLPERDDLAKKLVSAELKLDDTERR 238
+K +L+K EI E + L + KK A + D ER
Sbjct: 957 LESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERM 1016
Query: 239 IKEL------SKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERE 291
++ E + R+LL + R E N LQ E Q L +LK+ E +
Sbjct: 1017 VQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQ 1075
Score = 40.0 bits (92), Expect = 0.007
Identities = 50/231 (21%), Positives = 97/231 (41%), Gaps = 37/231 (16%)
Query: 105 LSARLLKINE----LQNEVSELQVKLAELLKENKSLKR----LQYRQEKALNKFEDAENE 156
L A++L + LQ + + LQ + A+L EN +L L + + L + ENE
Sbjct: 1079 LQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENE 1138
Query: 157 ISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLP 216
++ + + ++ +L + L K EK +R L +L+ + E H
Sbjct: 1139 -NESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHR- 1196
Query: 217 ERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQ------RQLLAERKRAYEAHD- 269
+ +D +L+ + +L+D E+ +K + + L + + ++L E R +
Sbjct: 1197 DLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQ 1256
Query: 270 ---ENKVLQKEVQRL-----------------YHKLKEKERELDIKNIYSN 300
E +VLQ + + L + KLKE+ ++LDI + N
Sbjct: 1257 LLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLN 1307
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 71.6 bits (174), Expect = 2e-12
Identities = 78/361 (21%), Positives = 166/361 (45%), Gaps = 35/361 (9%)
Query: 111 KINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITA 170
KI E + ++ E + K+ E ++ + + RQE+ + + E+ ++++ ++
Sbjct: 308 KIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR 367
Query: 171 LKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAEL 230
L+E + + +EK R E+++ + E + + +K +E + R +R + K+ E
Sbjct: 368 LEEMMWEKEEKIRELEEKMHEQE----KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 423
Query: 231 KLDDTERRIKELSKNLELSTNSF--QRQLLAERKRAYEAH---DENKVL-QKEVQRLYHK 284
K+ + E +I+E K + Q ++ E KR + E K+ Q+E+ R K
Sbjct: 424 KIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK 483
Query: 285 LKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEY 344
+ E+E+ + + K +EK + Q + K + E + +E
Sbjct: 484 MHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEE------KIREQEEKIREQEE 537
Query: 345 PLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQE 404
+ + M E + E+ G +Q Q++ R E I E+EEK E+ ++++
Sbjct: 538 KIREQEEMMQEQE-EKMGEQEEKMQEQEKMRRQE----EKIREQEEKI--REQKEKIREQ 590
Query: 405 VEKLEDEWEREELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKR 464
EK+ WE+EE ++Q+E +++ +E+ WE + +K+Q E+EE+++R
Sbjct: 591 EEKI---WEQEEKIREQEE---MMQEQEEKMWEQEEKMC-----EQEEKMQ-EQEEKMRR 638
Query: 465 E 465
+
Sbjct: 639 Q 639
Score = 60.8 bits (146), Expect = 4e-09
Identities = 89/430 (20%), Positives = 186/430 (43%), Gaps = 65/430 (15%)
Query: 112 INELQNEVSELQVKLAELLKE----NKSLKRLQYRQEKALNKFEDAENE---ISQLIFRH 164
+ +L+ E +L +L + K ++L + +++KA E+ E +S ++R+
Sbjct: 153 VKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRN 212
Query: 165 NNEITALKERLRKSQEKERATEKR-------VKDTESELFRTKFSLQKLKEISEARHL-- 215
LKE+ K QEK + E VK+ + +L R K L + + +EA HL
Sbjct: 213 TITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGK 272
Query: 216 ------------PERDDL---------------AKKLVSAELKLDDTERRIKELSKNLEL 248
E ++L +K+ E K+ + E +I+E + +
Sbjct: 273 ELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIRE 332
Query: 249 STNSFQRQ--LLAER----KRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSNRL 302
+RQ ++ E+ +R E E + + ++ + + +EK REL+ K ++
Sbjct: 333 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKI 392
Query: 303 PKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPG 362
+ +++E +R+ Q A + + + E + E+ + + E K E
Sbjct: 393 REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE--QEEKIREQEKKMWRQEEKIHEQE 450
Query: 363 HLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELH----VVKQE------VEKLEDEW 412
+ + + Q+Q+ I E+EE + E++H + KQE EK+ D+
Sbjct: 451 KIREEEKRQEQEEMWRQE--EKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQE 508
Query: 413 E--REELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAK 470
E RE+ +K +++ + E+EEK + + + +Q ++ GE+EE+++ + + +
Sbjct: 509 EKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRR 568
Query: 471 LNEIDRELQD 480
E RE ++
Sbjct: 569 QEEKIREQEE 578
Score = 48.1 bits (113), Expect = 3e-05
Identities = 99/463 (21%), Positives = 193/463 (41%), Gaps = 80/463 (17%)
Query: 35 RSSLVSSSPASVRRKNPKRQTSDGQVHHQAPRKPSPKGLPNRKGVRVGFRSQSLNREPLR 94
R S ++ + + +P+ S G +K G G S ++
Sbjct: 56 RQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASH 115
Query: 95 KDTDLVTKRILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAE 154
+ + + +R L A++ I L + +ELQ+ L ++K+L+ +++ D+
Sbjct: 116 QHQEAL-RRELEAQVHTIRILTCQKTELQMAL---YYSQHAVKQLEGEARDLISRLHDSW 171
Query: 155 NEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTES---ELFRTKFSLQKLKEISE 211
+L ++A+ + +K+ +R E+ K+ ++ EL+R + ++LKE
Sbjct: 172 KFAGEL----EQALSAVATQKKKA---DRYIEELTKERDALSLELYRNTITDEELKE--- 221
Query: 212 ARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDEN 271
+ L +KL E + + + +KEL + LE + + LL +++ EA
Sbjct: 222 -----KNAKLQEKLQLVESEKSEIQLNVKELKRKLERA-----KLLLPQQQLQAEADHLG 271
Query: 272 KVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTK 331
K LQ +L +++E E NRL N+++E + + +
Sbjct: 272 KELQSVSAKLQAQVEENE--------LWNRL-----NQQQEEKMWRQE-----------E 307
Query: 332 GVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEK 391
+Q E+ E+ E I E K E Q +K R E + E+EEK
Sbjct: 308 KIQEWEEKIQEQ----EEKIREQEEKIRE--------QEEKMRRQEEM-----MWEKEEK 350
Query: 392 FVTDEELHVVKQE-VEKLEDE-WEREE----LDKKQKEKASLLEREEKPEWETG------ 439
EE+ K+E + +LE+ WE+EE L++K E+ + E+EEK + E
Sbjct: 351 MRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK 410
Query: 440 RYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQDSR 482
R + + +K++ +EE+ ++E + + E E + R
Sbjct: 411 RQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIR 453
Score = 35.8 bits (81), Expect = 0.14
Identities = 19/102 (18%), Positives = 54/102 (52%)
Query: 111 KINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITA 170
K+ + ++ E + K+ E ++ + + + QE+ + + E+ E + ++ ++
Sbjct: 565 KMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCE 624
Query: 171 LKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEA 212
+E++++ +EK R E+++ + E L + + +Q+ +E EA
Sbjct: 625 QEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 666
Score = 35.4 bits (80), Expect = 0.18
Identities = 38/240 (15%), Positives = 101/240 (42%), Gaps = 22/240 (9%)
Query: 46 VRRKNPKRQTSDGQVHHQAPRKPSPKGLPNRKGVRVGFRSQSLNREPLRKDTDLVTKRIL 105
+R + K + ++H Q + K + R E +R+ ++ ++
Sbjct: 432 IREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWR--------QEEKIREQEEIWRQKEK 483
Query: 106 SARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLI---- 161
KI + + +V + K+ + ++ + + +RQE+ + + E+ E + I
Sbjct: 484 MHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQE 543
Query: 162 --FRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKE--ISEARHLPE 217
+ E +E + QEK R E+++++ E ++ K +++ +E + + E
Sbjct: 544 EMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIRE 603
Query: 218 RDDL----AKKLVSAELKLDDTERRIKELSKNLELSTNSF--QRQLLAERKRAYEAHDEN 271
++++ +K+ E K+ + E +++E + + Q L +++ + H E+
Sbjct: 604 QEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEH 663
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 71.2 bits (173), Expect = 3e-12
Identities = 78/399 (19%), Positives = 175/399 (43%), Gaps = 24/399 (6%)
Query: 111 KINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITA 170
KI E + ++ E + K+ E ++ + + RQE+ + + E+ ++++ ++
Sbjct: 308 KIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR 367
Query: 171 LKERLRKSQEKERATEKRVKDTES---ELFRTKFSLQKLKEISEARHLPERDDLAKKLVS 227
+E + + +EK R E+ + + E EL +K++E E R E+ +K
Sbjct: 368 QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 427
Query: 228 AELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKE 287
E K+ E +I+E + + RQ ++ +E + Q+E+ R K+ E
Sbjct: 428 QEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHE 487
Query: 288 KERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLT 347
+E K + K +EK + Q + + + E+ E+ +
Sbjct: 488 QEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMW 547
Query: 348 PETIMCYENK--WEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEV 405
E +E + WEE + + +++D+ M R+E+ + ++E V +QE
Sbjct: 548 REEEKMHEQEKIWEE------EKRQEQEDK----------MWRQEEKIREQEEKVWRQEE 591
Query: 406 EKLEDEWEREELDKKQ-KEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKR 464
+ E E +R+E ++K K++ + E+EEK + + + + I+ +++ E+EE++
Sbjct: 592 KIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGE 651
Query: 465 EMLLAKLNEIDRELQDSRNLKYPVLPLLPDFESKLHSPE 503
+ K+ E + ++Q+ + + + E K+ E
Sbjct: 652 QE--EKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQE 688
Score = 57.8 bits (138), Expect = 3e-08
Identities = 73/411 (17%), Positives = 184/411 (44%), Gaps = 45/411 (10%)
Query: 111 KINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITA 170
KI E + ++ E + K+ E ++ + + + + +E+ + + E+ E + + R +
Sbjct: 315 KIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWE 374
Query: 171 LKERLRKSQEKERATEKRVKDTESELF---RTKFSLQKLKEISEARHLPERDDLAKKLVS 227
+E++R+ +E E+++++ E ++ + + +K +E + R +R + K+
Sbjct: 375 KEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWR 434
Query: 228 AELKLDDTERRIKELSKNL--------------ELSTNSFQRQLLAERKRAYEA------ 267
E K+ + E +I+E K + E Q ++ + ++ +E
Sbjct: 435 QEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQ 494
Query: 268 ----HDENKVLQKEVQRLYHKLKE-KERELDIKNIYSNRLPKSSPNKEKELALRKNAACQ 322
H++ + ++K+ ++++ + ++ +E+E I+ + +E+E R+
Sbjct: 495 KEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMH 554
Query: 323 SDFADLCTKGVQTMEDF---KPEEYPLTPETIMCYENKWEEPGHLTLDLQSQ--KQD--- 374
+ Q ED + E+ E + E K E + + + KQ+
Sbjct: 555 EQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKI 614
Query: 375 RHGEAGILNP---IMEREEKFVTDEELHVVKQEVEKLEDEWER--EELDKKQKEKASLLE 429
R E I I E+EEK EE+ +++ EK+ ++ E+ E+ +K Q+++ ++
Sbjct: 615 REQEEKIQEQEEKIREQEEKIREQEEM--TQEQEEKMGEQEEKMCEQEEKMQEQEETMWR 672
Query: 430 REEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQD 480
+EEK + + + I+ +++ E+EE++ + K+ E + ++Q+
Sbjct: 673 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQE--EKMCEQEEKMQE 721
Score = 57.0 bits (136), Expect = 6e-08
Identities = 72/374 (19%), Positives = 170/374 (45%), Gaps = 40/374 (10%)
Query: 114 ELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKE 173
E + ++ EL+ K+ E + K ++ + RQE+ + ++ E ++R +I +E
Sbjct: 388 EKEEKIRELEEKMHE---QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 444
Query: 174 RLRKSQEK-----------ERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLA 222
++R+ ++K E+ E+ + + E++R + + + +EI R + +
Sbjct: 445 KIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIW--RQKEKMHEQE 502
Query: 223 KKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLY 282
+K+ E K+ E +I+E + + RQ R++ +E K+ ++E
Sbjct: 503 EKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQE----- 557
Query: 283 HKLKEKERELDIKNIYSNRLPKSSPNKEK----ELALRKNAACQSDFADLCTKGVQTMED 338
K+ E+E+ + ++ + K +EK E +R+ + + + K + + +
Sbjct: 558 -KIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIRE 616
Query: 339 FKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEEL 398
+ E+ E I E K E +T +++++ GE + E+EEK EE
Sbjct: 617 -QEEKIQEQEEKIREQEEKIREQEEMT----QEQEEKMGEQE--EKMCEQEEKMQEQEET 669
Query: 399 -----HVVKQEVEKLEDEWE--REELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNM 451
++++ +K+ ++ E RE+ + Q+++ + E+EEK + + Q ++
Sbjct: 670 MWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 729
Query: 452 DKLQGEEEERLKRE 465
++ E+E RL+++
Sbjct: 730 EEKMWEQEVRLRQQ 743
Score = 52.8 bits (125), Expect = 1e-06
Identities = 79/380 (20%), Positives = 163/380 (42%), Gaps = 52/380 (13%)
Query: 112 INELQNEVSELQVKLAELLKE----NKSLKRLQYRQEKALNKFEDAENE---ISQLIFRH 164
+ +L+ E +L +L + K ++L + +++KA E+ E +S ++R+
Sbjct: 153 VKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRN 212
Query: 165 NNEITALKERLRKSQEKERATEKR-------VKDTESELFRTKFSLQKLKEISEARHLPE 217
LKE+ K QEK + E VK+ + +L R K L + + +EA H
Sbjct: 213 TITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADH--- 269
Query: 218 RDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKE 277
L K+L S KL ++ +N EL Q+Q ++ + ++ + +++
Sbjct: 270 ---LGKELQSVSAKLQ------AQVEEN-ELWNRLNQQQ----EEKMWRQEEKIQEWEEK 315
Query: 278 VQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTME 337
+Q K++E+E ++ +E+E +R+ + + + + M
Sbjct: 316 IQEQEEKIREQEEKI----------------REQEEKMRRQEEMMWEKEEKMRRQEEMMW 359
Query: 338 DFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEE 397
+ K E+ E + E K + + + + ++ + I E+EEK +E+
Sbjct: 360 E-KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK 418
Query: 398 LHVVKQEVEKLEDEWEREELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGE 457
+ ++ E+ W +EE ++Q+EK + +EK W I+ +K Q E
Sbjct: 419 IREQEKRQEQEAKMWRQEEKIREQEEK---IREQEKKMWRQEEKIHEQEKIREEEKRQ-E 474
Query: 458 EEERLKREMLLAKLNEIDRE 477
+EE ++E + + EI R+
Sbjct: 475 QEEMWRQEEKIHEQEEIWRQ 494
Score = 41.2 bits (95), Expect = 0.003
Identities = 27/135 (20%), Positives = 68/135 (50%), Gaps = 9/135 (6%)
Query: 111 KINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITA 170
KI E + ++ E + K+ E + + + QE+ + + E+ E + ++R +I
Sbjct: 620 KIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIRE 679
Query: 171 LKERLRKSQEKERATEKRVKDTESELFRTKFSL----QKLKEISEARHLPERDDLAKKLV 226
++++R+ +EK R E+ +++ E +++ + + +K++E E E +K+
Sbjct: 680 QEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE-----EKMW 734
Query: 227 SAELKLDDTERRIKE 241
E++L E +++E
Sbjct: 735 EQEVRLRQQEEKMQE 749
Score = 38.5 bits (88), Expect = 0.021
Identities = 32/182 (17%), Positives = 88/182 (48%), Gaps = 19/182 (10%)
Query: 111 KINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITA 170
KI E + +V + K+ E ++ + + ++QE+ + + E+ E +I
Sbjct: 578 KIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQE-------QEEKIRE 630
Query: 171 LKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAEL 230
+E++R+ +E + E+++ + E ++ + +K++E E E +K+ E
Sbjct: 631 QEEKIREQEEMTQEQEEKMGEQEEKMCEQE---EKMQEQEETMWRQE-----EKIREQEK 682
Query: 231 KLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKER 290
K+ + E +I+E + ++ + ++ + ++ E ++ + +++++R K+ E+E
Sbjct: 683 KIREQEEKIREQEEMMQ----EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 738
Query: 291 EL 292
L
Sbjct: 739 RL 740
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 70.9 bits (172), Expect = 4e-12
Identities = 90/438 (20%), Positives = 196/438 (44%), Gaps = 54/438 (12%)
Query: 99 LVTKRILSARLLKINELQ----NEVSELQVKLAELLKENKSLK-RLQ--YRQEKALNKFE 151
LV+K+ L RL+++ E + N+ LQ+++ ++L++N++LK ++Q + Q A
Sbjct: 540 LVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSAS 599
Query: 152 DAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISE 211
E+ ++I + +I ++ L +++ + E+ +KD ++ F K +QKL+
Sbjct: 600 VLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQA--- 656
Query: 212 ARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDEN 271
LA + +A +L+ ++ + + L Q ++ + + +D+N
Sbjct: 657 ---------LANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQN 707
Query: 272 KVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTK 331
K L+ EVQ+L + E+ + ++ ++ K K+++L + ++ + TK
Sbjct: 708 KALKSEVQKLQTLVSEQPNKDVVE-----QMEKCIQEKDEKLKTVEE-LLETGLIQVATK 761
Query: 332 GVQTMEDFKPEEYPLTPET--IMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMERE 389
+ + + E LT E + +N L +L+ ++ G+ + ++E E
Sbjct: 762 -EEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAE 820
Query: 390 EKFVTDEELHV--VKQEVEKLEDEWEREELDKKQ-----------------KEK-----A 425
V ++E V +KQE++ L++E +L+K Q KE+
Sbjct: 821 LLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMK 880
Query: 426 SLLEREEKPEWETGRYQLGMYPIQNMDKLQGEE--EERLKREMLLAKLNEIDRELQDSRN 483
++LE +EK TG++ + K +E + LK ++ E++ L++ N
Sbjct: 881 AVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKEN 940
Query: 484 LKYPVLPLLPDFESKLHS 501
+ +L + ES L S
Sbjct: 941 ELKRLEAMLKERESDLSS 958
Score = 45.4 bits (106), Expect = 2e-04
Identities = 92/453 (20%), Positives = 190/453 (41%), Gaps = 80/453 (17%)
Query: 102 KRILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLI 161
+ +L A LLK+ + V +L+ ++ L +E +++ + +Q +K ++ +N L+
Sbjct: 814 EELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQN----LL 869
Query: 162 FRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKE--ISEARHLPERD 219
++ +K L + ++ T K ++D + E K +Q++ + + EA + +
Sbjct: 870 KGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFE 929
Query: 220 DLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQ 279
+L L E +L E +KE +L T Q + DENK+ + +++
Sbjct: 930 ELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQ-----------DVQDENKLFKSQIE 978
Query: 280 RLYHK-----------------LKEKEREL--------DIKNIYSNRLPKSSPNKEKEL- 313
+L + + E+E+E+ +K+ ++ K++ +EK
Sbjct: 979 QLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWE 1038
Query: 314 ALRKNAACQSDFADLCTK-------GVQTME-DFKPEEYPLTP-----------ETIMCY 354
A+ A+ + D K V+ +E + K L P E + +
Sbjct: 1039 AMEALASTEKMLQDKVNKTSKERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGF 1098
Query: 355 ENKWEEPGHLTLDLQSQKQDRH--GEAGILNPIMERE-EKF-----VTDEELHVVKQEVE 406
E K +E T + K H EA ++ +++ E EK+ T+ L +++ VE
Sbjct: 1099 EKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVE 1158
Query: 407 KLEDEWEREELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREM 466
+ E++W + ++D+ K + E E R + I+N+ + E E L+ E+
Sbjct: 1159 QEENKW-KVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRR----EREHLEMEL 1213
Query: 467 LLAKLNEIDRELQDSRNLKYPVLPLLPDFESKL 499
A++ E + + R LK LL + + KL
Sbjct: 1214 EKAEM-ERSTYVTEVRELK----DLLTELQKKL 1241
Score = 37.7 bits (86), Expect = 0.036
Identities = 73/383 (19%), Positives = 144/383 (37%), Gaps = 51/383 (13%)
Query: 103 RILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFED-AENEISQLI 161
+++S R +I+ L NE+ L+ + K+N L+ + +AL E ++++++
Sbjct: 999 KVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTS 1058
Query: 162 FRHNNEITAL----KERLRKSQEKE------------RATEKRVKDT---ESELFRTKFS 202
++ A+ KE L+K K EK+ K+ S K
Sbjct: 1059 KERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVL 1118
Query: 203 LQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERK 262
KLKE E L + + K V AE TE +++L +++E N ++ ++ K
Sbjct: 1119 EHKLKEADEMHTLLQLECEKYKSVLAE-----TEGILQKLQRSVEQEENKWKVKVDESHK 1173
Query: 263 RAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQ 322
+ ++E++RL + DI+N+ R ++ E+
Sbjct: 1174 TIKQMQSSFTSSEQELERL------RSENKDIENLRREREHLEMELEKAEMERSTYVTEV 1227
Query: 323 SDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGIL 382
+ DL T+ + ++D E E + + L++++ +R AG
Sbjct: 1228 RELKDLLTELQKKLDDSYSEAVRQNEELNLLK----AQLNETLTKLRTEQNERQKVAG-- 1281
Query: 383 NPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLEREEKPEWETGRYQ 442
+LH +Q +E ++ + + D E + + E E ET
Sbjct: 1282 --------------DLHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVS 1327
Query: 443 LGMYPIQNMDKLQGEEEERLKRE 465
L Q LQ ++ K +
Sbjct: 1328 LNQTVTQLQQLLQAVNQQLTKEK 1350
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 70.9 bits (172), Expect = 4e-12
Identities = 90/438 (20%), Positives = 196/438 (44%), Gaps = 54/438 (12%)
Query: 99 LVTKRILSARLLKINELQ----NEVSELQVKLAELLKENKSLK-RLQ--YRQEKALNKFE 151
LV+K+ L RL+++ E + N+ LQ+++ ++L++N++LK ++Q + Q A
Sbjct: 540 LVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSAS 599
Query: 152 DAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISE 211
E+ ++I + +I ++ L +++ + E+ +KD ++ F K +QKL+
Sbjct: 600 VLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQA--- 656
Query: 212 ARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDEN 271
LA + +A +L+ ++ + + L Q ++ + + +D+N
Sbjct: 657 ---------LANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQN 707
Query: 272 KVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTK 331
K L+ EVQ+L + E+ + ++ ++ K K+++L + ++ + TK
Sbjct: 708 KALKSEVQKLQTLVSEQPNKDVVE-----QMEKCIQEKDEKLKTVEE-LLETGLIQVATK 761
Query: 332 GVQTMEDFKPEEYPLTPET--IMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMERE 389
+ + + E LT E + +N L +L+ ++ G+ + ++E E
Sbjct: 762 -EEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAE 820
Query: 390 EKFVTDEELHV--VKQEVEKLEDEWEREELDKKQ-----------------KEK-----A 425
V ++E V +KQE++ L++E +L+K Q KE+
Sbjct: 821 LLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMK 880
Query: 426 SLLEREEKPEWETGRYQLGMYPIQNMDKLQGEE--EERLKREMLLAKLNEIDRELQDSRN 483
++LE +EK TG++ + K +E + LK ++ E++ L++ N
Sbjct: 881 AVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKEN 940
Query: 484 LKYPVLPLLPDFESKLHS 501
+ +L + ES L S
Sbjct: 941 ELKRLEAMLKERESDLSS 958
Score = 50.1 bits (118), Expect = 7e-06
Identities = 86/435 (19%), Positives = 172/435 (39%), Gaps = 100/435 (22%)
Query: 102 KRILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLI 161
+ +L A LLK+ + V +L+ ++ L +E +++ + +Q +K ++ +N L+
Sbjct: 814 EELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQN----LL 869
Query: 162 FRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKE--ISEARHLPERD 219
++ +K L + ++ T K ++D + E K +Q++ + + EA + +
Sbjct: 870 KGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFE 929
Query: 220 DLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQ 279
+L L E +L E +KE +L T Q + DENK+ + +++
Sbjct: 930 ELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQ-----------DVQDENKLFKSQIE 978
Query: 280 RLYHK-----------------LKEKEREL--------DIKNIYSNRLPKSSPNKEKELA 314
+L + + E+E+E+ +K+ ++ K++ +++ A
Sbjct: 979 QLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNERQQQVEA 1038
Query: 315 LRKNA-----------ACQSDF------------ADLCTKGVQTMEDFKPEEYPLTPETI 351
+ A + S+ A C G E+ K E+ L
Sbjct: 1039 VELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKL----- 1093
Query: 352 MCYENKWEEPGHLTLDLQSQK-----QDRHGEAGILNPIMEREE---KFVTDEELHVVK- 402
K + H L L+ +K + G L +E+EE K DE +K
Sbjct: 1094 -----KEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQ 1148
Query: 403 ---------QEVEKLEDEWEREELDKKQKEKASLLEREEKPEWETGRY-----QLGMYPI 448
QE+E+L E ++++ ++E+ L EK E E Y +L
Sbjct: 1149 MQSSFTSSEQELERLRS--ENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKAQLN 1206
Query: 449 QNMDKLQGEEEERLK 463
+ + KL+ E+ ER K
Sbjct: 1207 ETLTKLRTEQNERQK 1221
Score = 42.4 bits (98), Expect = 0.001
Identities = 75/379 (19%), Positives = 145/379 (38%), Gaps = 59/379 (15%)
Query: 105 LSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRH 164
LS++ + ++Q+E + ++ +L ++N E+ L + E EIS L
Sbjct: 956 LSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLW--- 1012
Query: 165 NNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKK 224
NE+ +LK+ + ++K +++V+ E E K L+KL K
Sbjct: 1013 -NELDSLKDAVEHQRKKNNERQQQVEAVELE---AKEVLKKL--------------FPKV 1054
Query: 225 LVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHK 284
V + L + ++ +K T+ + + E K EA + + +LQ E ++
Sbjct: 1055 SVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHK-LKEADEMHTLLQLECEKYKSV 1113
Query: 285 LKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAA------CQSDFADLCTKGVQTMED 338
L E E L +L +S +E + ++ + + QS F T Q +E
Sbjct: 1114 LAETEGIL-------QKLQRSVEQEENKWKVKVDESHKTIKQMQSSF----TSSEQELER 1162
Query: 339 FKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPI------------M 386
+ E + EN E HL ++L+ + +R + +
Sbjct: 1163 LRSENKDI--------ENLRREREHLEMELEKAEMERSTYVTEVRELKAQLNETLTKLRT 1214
Query: 387 EREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLEREEKPEWETGRYQLGMY 446
E+ E+ +LH +Q +E ++ + + D E + + E E ET L
Sbjct: 1215 EQNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVSLNQT 1274
Query: 447 PIQNMDKLQGEEEERLKRE 465
Q LQ ++ K +
Sbjct: 1275 VTQLQQLLQAVNQQLTKEK 1293
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 70.9 bits (172), Expect = 4e-12
Identities = 90/438 (20%), Positives = 196/438 (44%), Gaps = 54/438 (12%)
Query: 99 LVTKRILSARLLKINELQ----NEVSELQVKLAELLKENKSLK-RLQ--YRQEKALNKFE 151
LV+K+ L RL+++ E + N+ LQ+++ ++L++N++LK ++Q + Q A
Sbjct: 540 LVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSAS 599
Query: 152 DAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISE 211
E+ ++I + +I ++ L +++ + E+ +KD ++ F K +QKL+
Sbjct: 600 VLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQA--- 656
Query: 212 ARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDEN 271
LA + +A +L+ ++ + + L Q ++ + + +D+N
Sbjct: 657 ---------LANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQN 707
Query: 272 KVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTK 331
K L+ EVQ+L + E+ + ++ ++ K K+++L + ++ + TK
Sbjct: 708 KALKSEVQKLQTLVSEQPNKDVVE-----QMEKCIQEKDEKLKTVEE-LLETGLIQVATK 761
Query: 332 GVQTMEDFKPEEYPLTPET--IMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMERE 389
+ + + E LT E + +N L +L+ ++ G+ + ++E E
Sbjct: 762 -EEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAE 820
Query: 390 EKFVTDEELHV--VKQEVEKLEDEWEREELDKKQ-----------------KEK-----A 425
V ++E V +KQE++ L++E +L+K Q KE+
Sbjct: 821 LLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMK 880
Query: 426 SLLEREEKPEWETGRYQLGMYPIQNMDKLQGEE--EERLKREMLLAKLNEIDRELQDSRN 483
++LE +EK TG++ + K +E + LK ++ E++ L++ N
Sbjct: 881 AVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKEN 940
Query: 484 LKYPVLPLLPDFESKLHS 501
+ +L + ES L S
Sbjct: 941 ELKRLEAMLKERESDLSS 958
Score = 45.4 bits (106), Expect = 2e-04
Identities = 92/453 (20%), Positives = 190/453 (41%), Gaps = 80/453 (17%)
Query: 102 KRILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLI 161
+ +L A LLK+ + V +L+ ++ L +E +++ + +Q +K ++ +N L+
Sbjct: 814 EELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQN----LL 869
Query: 162 FRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKE--ISEARHLPERD 219
++ +K L + ++ T K ++D + E K +Q++ + + EA + +
Sbjct: 870 KGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFE 929
Query: 220 DLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQ 279
+L L E +L E +KE +L T Q + DENK+ + +++
Sbjct: 930 ELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQ-----------DVQDENKLFKSQIE 978
Query: 280 RLYHK-----------------LKEKEREL--------DIKNIYSNRLPKSSPNKEKEL- 313
+L + + E+E+E+ +K+ ++ K++ +EK
Sbjct: 979 QLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWE 1038
Query: 314 ALRKNAACQSDFADLCTK-------GVQTME-DFKPEEYPLTP-----------ETIMCY 354
A+ A+ + D K V+ +E + K L P E + +
Sbjct: 1039 AMEALASTEKMLQDKVNKTSKERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGF 1098
Query: 355 ENKWEEPGHLTLDLQSQKQDRH--GEAGILNPIMERE-EKF-----VTDEELHVVKQEVE 406
E K +E T + K H EA ++ +++ E EK+ T+ L +++ VE
Sbjct: 1099 EKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVE 1158
Query: 407 KLEDEWEREELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREM 466
+ E++W + ++D+ K + E E R + I+N+ + E E L+ E+
Sbjct: 1159 QEENKW-KVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRR----EREHLEMEL 1213
Query: 467 LLAKLNEIDRELQDSRNLKYPVLPLLPDFESKL 499
A++ E + + R LK LL + + KL
Sbjct: 1214 EKAEM-ERSTYVTEVRELK----DLLTELQKKL 1241
Score = 37.7 bits (86), Expect = 0.036
Identities = 73/383 (19%), Positives = 144/383 (37%), Gaps = 51/383 (13%)
Query: 103 RILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFED-AENEISQLI 161
+++S R +I+ L NE+ L+ + K+N L+ + +AL E ++++++
Sbjct: 999 KVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTS 1058
Query: 162 FRHNNEITAL----KERLRKSQEKE------------RATEKRVKDT---ESELFRTKFS 202
++ A+ KE L+K K EK+ K+ S K
Sbjct: 1059 KERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVL 1118
Query: 203 LQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERK 262
KLKE E L + + K V AE TE +++L +++E N ++ ++ K
Sbjct: 1119 EHKLKEADEMHTLLQLECEKYKSVLAE-----TEGILQKLQRSVEQEENKWKVKVDESHK 1173
Query: 263 RAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQ 322
+ ++E++RL + DI+N+ R ++ E+
Sbjct: 1174 TIKQMQSSFTSSEQELERL------RSENKDIENLRREREHLEMELEKAEMERSTYVTEV 1227
Query: 323 SDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGIL 382
+ DL T+ + ++D E E + + L++++ +R AG
Sbjct: 1228 RELKDLLTELQKKLDDSYSEAVRQNEELNLLK----AQLNETLTKLRTEQNERQKVAG-- 1281
Query: 383 NPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLEREEKPEWETGRYQ 442
+LH +Q +E ++ + + D E + + E E ET
Sbjct: 1282 --------------DLHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVS 1327
Query: 443 LGMYPIQNMDKLQGEEEERLKRE 465
L Q LQ ++ K +
Sbjct: 1328 LNQTVTQLQQLLQAVNQQLTKEK 1350
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 70.9 bits (172), Expect = 4e-12
Identities = 101/504 (20%), Positives = 208/504 (41%), Gaps = 52/504 (10%)
Query: 28 ETPQSSGRSSLVSSSPASVRRKNPKRQTSDGQVHHQAPRKPSPKGLPNRKGVRVGFRSQS 87
E P+ R L+ S RR+ R+ + + R+ + L R ++ +
Sbjct: 623 EEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQR--LKREHEEER 680
Query: 88 LNREPLRKDTDLVTKRILSARLLKIN-ELQNEVSELQVKLAELLKENKSLKRLQYRQEKA 146
+E ++ + +RI S R+ K +L++E Q K+ ++ + +R Q ++EK
Sbjct: 681 REQELAEEEQEQARERIKS-RIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKR 739
Query: 147 LNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKL 206
+ + + + + R E +E+ R + +A EK + + R Q+
Sbjct: 740 RRRESELQWQEEERAHRQQQE----EEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRE 795
Query: 207 KEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYE 266
+++ ER ++ + E + + R+ +E K L+ Q Q R+RA +
Sbjct: 796 RQL----RAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQ---RRERAQQ 848
Query: 267 AHDENKVLQKEVQRLYHKLK----------EKERELDIKNIYSNRLPKSSPNKEKELALR 316
+E LQ++ +R + + E+ER+ +Y+ + KE++L
Sbjct: 849 LQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQE 908
Query: 317 KNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRH 376
+ Q + + + Q + + E+ E ++ E + + ++Q+R
Sbjct: 909 EEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREERE-----------KRRRQERE 957
Query: 377 GEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLEREEK--- 433
+ + ++EE+ + +E +QE EK REE + +Q+E+ L E EK
Sbjct: 958 RQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKY----REEEELQQEEEQLLREEREKRRR 1013
Query: 434 PEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQDSRNLKYPVLPLLP 493
EWE + D+LQ EEE+ L+ E +L E +R+ ++ L+ LL
Sbjct: 1014 QEWER--------QYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLG 1065
Query: 494 DFESKLHSPERSPKTYRFSESSER 517
+ E + + + YR E ++
Sbjct: 1066 E-ERETRRRQELERQYRKEEELQQ 1088
Score = 69.3 bits (168), Expect = 1e-11
Identities = 97/424 (22%), Positives = 186/424 (43%), Gaps = 40/424 (9%)
Query: 105 LSAR--LLKINELQNEVSELQVKLAELL--KENKSLKRLQYRQEKALNKFEDAENEISQL 160
LSAR L + E Q E Q + L +E K +R Q R+ + +F + E ++ +
Sbjct: 784 LSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRR 843
Query: 161 IFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARH-LPERD 219
++ ++ L++ QE+ R+ E+R K+ Q +E RH L +
Sbjct: 844 --ERAQQLQEEEDGLQEDQERRRSQEQRRDQ--------KWRWQLEEERKRRRHTLYAKP 893
Query: 220 DLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQ 279
L ++L + L + E EL +++ E++R Y E + LQ+E +
Sbjct: 894 ALQEQLRKEQQLLQEEEE---------ELQREEREKRRRQEQERQYR---EEEQLQQEEE 941
Query: 280 RLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDF 339
+L + +EK R + + Y R K KE++L + + + + + ++
Sbjct: 942 QLLREEREKRRRQERERQY--RKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQ-- 997
Query: 340 KPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELH 399
+ EE L E +WE +LQ +++ E + ERE ++ +EEL
Sbjct: 998 QEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQ 1057
Query: 400 VVKQEVEKLEDEWE---REELDKKQKEKASLLEREE---KPEWETGRYQLGMYPIQNMDK 453
++E + L +E E R+EL+++ +++ L + EE + E E R Q + ++
Sbjct: 1058 --QEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEE 1115
Query: 454 LQGEEEERLKREMLLAKLNEIDRELQDSRNLKYPVLPLLPDFESKLHSPERSPKTYRFSE 513
LQ EEE+ L+ E + E++R+ ++ ++ LL + K E + YR E
Sbjct: 1116 LQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELE-RQYREEE 1174
Query: 514 SSER 517
++
Sbjct: 1175 ELQQ 1178
Score = 63.2 bits (152), Expect = 8e-10
Identities = 112/520 (21%), Positives = 208/520 (40%), Gaps = 90/520 (17%)
Query: 48 RKNPKRQTSDGQVHHQAPRKPSPKGLPNRKGVRVGFRSQSLNREPLRKDTDLVTKRILSA 107
RK+ K Q + Q+ + P K + K R Q + LR++ + ++
Sbjct: 961 RKDKKLQQKEEQLLGEEPEKRRRQ--EREKKYREEEELQQEEEQLLREEREKRRRQEWER 1018
Query: 108 RLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNE 167
+ K +ELQ E +L L+E + +RLQ R E+ + E+ + E QL+
Sbjct: 1019 QYRKKDELQQEEEQL-------LREEREKRRLQER-ERQYREEEELQQEEEQLLGEER-- 1068
Query: 168 ITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVS 227
+ R R+ E++ E+ ++ E +L L+E E R ER+ ++
Sbjct: 1069 ----ETRRRQELERQYRKEEELQQEEEQL---------LREEPEKRRRQERERQCREEEE 1115
Query: 228 AELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKE 287
+ + + R +E + EL + + + + + + K ++E++R Y
Sbjct: 1116 LQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQY----R 1171
Query: 288 KERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFK----PE- 342
+E EL + R + +E+E R+ Q + D K PE
Sbjct: 1172 EEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEK 1231
Query: 343 EYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEK----------- 391
E + + C + E+ L SQ +DR + + + + E++E+
Sbjct: 1232 ENAVRDNKVYCKGRENEQFRQLE---DSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQ 1288
Query: 392 ----FVTDEELHVVKQEV----------------EKLEDEWEREELDKKQKEKASLL-ER 430
F +E+L +Q+ E+ E++ R+E D+K +E+ LL ER
Sbjct: 1289 RDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQER 1348
Query: 431 EEKP-----------EWETGRYQLGMYPIQNMDKLQGEEEER--LKREMLLAKLNEIDRE 477
EE+P E E + G ++ +L+ +E ER LK E L + E +++
Sbjct: 1349 EEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQL-RCQEREQQ 1407
Query: 478 LQDSRNLKYPVLPLLPDFESKLHSPERSPKTYRFSESSER 517
L+ R+ K+ + E +L ER K +R E R
Sbjct: 1408 LRQDRDRKF------REEEQQLSRQERDRK-FREEEQQVR 1440
Score = 62.8 bits (151), Expect = 1e-09
Identities = 99/461 (21%), Positives = 193/461 (41%), Gaps = 52/461 (11%)
Query: 84 RSQSLNREPLRKDTDLVTKRILSARLLKINELQNEVSELQVKLAELLK------ENKSLK 137
R Q L RE + D + KR R ++ Q E E ++K E+ + + LK
Sbjct: 563 REQRLKREQEER-RDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLK 621
Query: 138 RLQYRQEKA--LNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESE 195
R + +E+ L K E+ E Q + R E ++RL++ +E+ER ++ ++ E E
Sbjct: 622 REEPEEERRQQLLKSEEQEERRQQQLRREQQE--RREQRLKREEEEERLEQRLKREHEEE 679
Query: 196 LFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLD-DTERRIKELSKNLELSTNSFQ 254
++ +E++E R+ + ++ + +L+ + + R ++ +
Sbjct: 680 --------RREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRR 731
Query: 255 RQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELA 314
RQ E++R E+++ +E +R + + +E+E+ D + + + S + L+
Sbjct: 732 RQEQEEKRR----RRESELQWQEEERAHRQQQEEEQRRDFT--WQWQAEEKSERGRQRLS 785
Query: 315 LRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQD 374
R Q + + Q + F PEE E + +E L + Q Q+++
Sbjct: 786 ARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRERE-KELQFLEEEEQLQRRE 844
Query: 375 RHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQ------------- 421
R + + E E+ D+E +++ + W+ EE K++
Sbjct: 845 RAQQ------LQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQ 898
Query: 422 --KEKASLLEREE---KPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDR 476
KE+ L E EE + E E R Q + ++LQ EEE+ L+ E + E +R
Sbjct: 899 LRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERER 958
Query: 477 ELQDSRNLKYPVLPLLPDFESKLHSPERSPKTYRFSESSER 517
+ + + L+ LL + K ER K YR E ++
Sbjct: 959 QYRKDKKLQQKEEQLLGEEPEKRRRQERE-KKYREEEELQQ 998
Score = 61.2 bits (147), Expect = 3e-09
Identities = 87/483 (18%), Positives = 208/483 (43%), Gaps = 54/483 (11%)
Query: 12 QERKAGKHHYSYLSDFETPQSSGRSSLVSSSPASVRRKN------PKRQTSDGQVHHQAP 65
+ER+A + ET + L +RRK +R+ D +
Sbjct: 184 EERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEE 243
Query: 66 RKPSPKGLPNRKGVRVGFRSQSLNREPLRKDTDLVTKRILSARLLKINELQNEVSELQVK 125
++ + RK + + L+++ + + K L + L+ + E + +++
Sbjct: 244 KEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRK--LERQELRRERQEEEQQQQRLR 301
Query: 126 LAELLKENKSLKRLQYRQEKA--LNKFEDAENEISQLIFRHNNEITALKERLRKSQEKER 183
+ L+ + +R + ++E+ + E E Q + R E +++LR+ QE+ER
Sbjct: 302 REQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEE--RREQQLRREQEEER 359
Query: 184 ATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELS 243
++ ++ E E R + L++ +++ + L L ++ +L+ + RR ++L
Sbjct: 360 REQQLRREQEEE--RREQQLRREQQLRREQQLRREQQLRRE---QQLRREQQLRREQQLR 414
Query: 244 KNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSNRLP 303
+ +L +R+ R++ E H++ ++ QRL K +++ER + L
Sbjct: 415 REQQL-----RREQQLRREQEEERHEQKHEQERREQRL--KREQEERR--------DWLK 459
Query: 304 KSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGH 363
+ + E RK + + + ++ E+ + E+ + + + + E
Sbjct: 460 REEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQR- 518
Query: 364 LTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQKE 423
L+ Q+++ + + + R E+ E+L + ++E ++LE E + L ++Q+E
Sbjct: 519 ----LKRQEEEERLQQRLRSEQQLRREQEERREQL-LKREEEKRLEQERREQRLKREQEE 573
Query: 424 KAS-LLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQDSR 482
+ LL+REE+ + +L+ E+EERL++ + ++ +++E + +
Sbjct: 574 RRDQLLKREEE---------------RRQQRLKREQEERLEQRLKREEVERLEQEERREQ 618
Query: 483 NLK 485
LK
Sbjct: 619 RLK 621
Score = 58.9 bits (141), Expect = 2e-08
Identities = 91/407 (22%), Positives = 173/407 (42%), Gaps = 35/407 (8%)
Query: 84 RSQSLNREP--------LRKDTDLVTKRILSARLLKINELQNEVSELQVKLAELLKENKS 135
R Q L RE LR++ + + R ++ Q E Q++ + L+ +
Sbjct: 347 REQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 406
Query: 136 LKR-LQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTE- 193
L+R Q R+E+ L + + E + +E ++RL++ QE+ R KR ++TE
Sbjct: 407 LRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETER 466
Query: 194 SELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSF 253
E R K L++ +E ER + KL E + + ERR ++L + E
Sbjct: 467 HEQERRKQQLKRDQE-------EERRERWLKLEEEE-RREQQERREQQLRREQEERREQR 518
Query: 254 QRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKEL 313
++ E + E ++ +++ +R LK +E + + RL + + +L
Sbjct: 519 LKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQL 578
Query: 314 ALRKNAACQSDFADLCTKGVQTMEDFKPEEYP-LTPETIMCYENKWEEPGHLTLD--LQS 370
R+ Q + ++ + K EE L E K EEP L+S
Sbjct: 579 LKREEERRQQRLKREQEERLE--QRLKREEVERLEQEERREQRLKREEPEEERRQQLLKS 636
Query: 371 QKQDRHGEAGILNPIME-REEKFVTDEELHVVKQEVEKLEDEWERE-ELDKKQKEKASLL 428
++Q+ + + E RE++ +EE ++Q +++ +E RE EL ++++E+A
Sbjct: 637 EEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARER 696
Query: 429 EREEKPEW------ETGRYQLGMY----PIQNMDKLQGEEEERLKRE 465
+ P+W E Q +Y + + Q +EE+R +RE
Sbjct: 697 IKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRE 743
Score = 58.9 bits (141), Expect = 2e-08
Identities = 110/472 (23%), Positives = 199/472 (42%), Gaps = 56/472 (11%)
Query: 71 KGLPNRKGVRVGFRSQSLNREPLRKDTDLVTKRILSARLLKINELQNEVSELQVKLAELL 130
K L + +R R Q L ++ RK + + R K E E QV+ E
Sbjct: 1391 KFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFRE-----EEQQVRRQE-- 1443
Query: 131 KENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVK 190
+E K L+ Q +++ KF + E QL+ + +ER RK E+E+ ++ +
Sbjct: 1444 RERKFLEEEQQLRQERHRKFREEE----QLLQEREEQQLHRQERDRKFLEEEQQLRRQER 1499
Query: 191 DT---ESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTER-------RIK 240
D E EL R++ +K E + H +R +K + E +L ER R +
Sbjct: 1500 DRKFREQEL-RSQEPERKFLEEEQQLHRQQRQ---RKFLQEEQQLRRQERGQQRRQDRDR 1555
Query: 241 ELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSN 300
+ + +L ++QL + + +E KV ++E +R K E E++L +
Sbjct: 1556 KFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQER---KFMEDEQQLRRQEGQQQ 1612
Query: 301 -RLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWE 359
R + +E E L++ Q + K ++ + +E + + K+
Sbjct: 1613 LRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQERE--QQLRHDRDRKFR 1670
Query: 360 EPGHLTLD-----LQSQKQDRH-GEAGILNPIMEREEKFVTDE------ELHVVKQEVEK 407
E L + L+ Q++DR E ERE KF+ +E EL +E E+
Sbjct: 1671 EEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQ 1730
Query: 408 LEDEWEREELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMD-KLQGEEEERLKREM 466
L E E+E+L ++++ + L E + +PE E + + Q D K + EE+ R +RE
Sbjct: 1731 LRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRR-----QERDRKFREEEQLRQEREE 1785
Query: 467 LLAKLNEIDRELQDSRNLKYPVLPLLPDFESKLHSPERSPKTYRFSESSERL 518
+ E DR+ ++ L+ + E + P++ YR+ E +L
Sbjct: 1786 QQLRSQESDRKFREEEQLR-------QEREEQQLRPQQRDGKYRWEEEQLQL 1830
Score = 55.1 bits (131), Expect = 2e-07
Identities = 79/375 (21%), Positives = 162/375 (43%), Gaps = 50/375 (13%)
Query: 137 KRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESEL 196
++L+ ++K + + E QL+ E K R +++ K R E+ +++ E +
Sbjct: 1297 EQLEREEQKEAKRRDRKSQEEKQLLREEREE----KRRRQETDRKFREEEQLLQEREEQP 1352
Query: 197 FRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQ 256
R + +K +E E RH + +K + E +L ER K L + +L ++Q
Sbjct: 1353 LRRQERDRKFRE-EELRH----QEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQ 1407
Query: 257 LLAERKRAYEAHDENKVLQKEVQRLYHK----LKEKERELD-IKNIYSNRLPKSSPNKEK 311
L +R R + +E ++ ++E R + + ++ +ERE ++ R + +E+
Sbjct: 1408 LRQDRDRKFR-EEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREE 1466
Query: 312 ELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLD---- 367
E L++ Q + K ++ + + +E E + +EP L+
Sbjct: 1467 EQLLQEREEQQLHRQERDRKFLEEEQQLRRQE---RDRKFREQELRSQEPERKFLEEEQQ 1523
Query: 368 ----------LQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWER--- 414
LQ ++Q R E G +R+ KF +E+L ++E + E +R
Sbjct: 1524 LHRQQRQRKFLQEEQQLRRQERGQQRR-QDRDRKFREEEQLRQEREEQQLSRQERDRKFR 1582
Query: 415 --EELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMDK--------LQGEEEERLKR 464
E+ ++Q+++ +E E++ + G+ QL Q D+ LQ EE++L R
Sbjct: 1583 LEEQKVRRQEQERKFMEDEQQLRRQEGQQQLR----QERDRKFREDEQLLQEREEQQLHR 1638
Query: 465 EMLLAKLNEIDRELQ 479
+ K E + +L+
Sbjct: 1639 QERDRKFLEEEPQLR 1653
Score = 52.0 bits (123), Expect = 2e-06
Identities = 78/333 (23%), Positives = 145/333 (43%), Gaps = 35/333 (10%)
Query: 115 LQNEVSELQVKLAELLKENKSLKRL----QYRQEKALNKFEDAENEISQLIFRHNNEITA 170
L+ + Q + + +++ + L+R Q RQE+ KF + E QL+ +
Sbjct: 1583 LEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERD-RKFREDE----QLLQEREEQQLH 1637
Query: 171 LKERLRKSQEKE-----RATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKL 225
+ER RK E+E + E++++ FR + L + E + R ERD +K
Sbjct: 1638 RQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRR-QERD---RKF 1693
Query: 226 VSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKL 285
E +L ER K L + +L +R+ E + E E Q Q Y K+
Sbjct: 1694 REEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQE----QLRRQERYRKI 1749
Query: 286 KEKER---ELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPE 342
E+E+ E + + + + +E+ R+ +S +D + + + + E
Sbjct: 1750 LEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQER-E 1808
Query: 343 EYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVK 402
E L P+ + +WEE L L+ Q+Q E + EE+F T E+ +
Sbjct: 1809 EQQLRPQQ-RDGKYRWEEE---QLQLEEQEQRLRQER---DRQYRAEEQFATQEKSRREE 1861
Query: 403 QEVEKLEDEWEREELDKKQKEKASLLEREEKPE 435
QE+ + E++ R+E ++K +E+ + R++K E
Sbjct: 1862 QELWQEEEQKRRQERERKLREEH--IRRQQKEE 1892
Score = 51.6 bits (122), Expect = 2e-06
Identities = 68/349 (19%), Positives = 149/349 (42%), Gaps = 55/349 (15%)
Query: 142 RQEKALNKFEDAENEISQLIFRHNNEITALKERL-----RKSQEKERATEKRVKDTESEL 196
RQE+ +FE + ++ + + + +ER +S+++ER ++ + + EL
Sbjct: 114 RQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEEL 173
Query: 197 FRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQ 256
+R + Q+ +E E R E+ K + E D+ + R +EL + Q+Q
Sbjct: 174 WRQR---QEWQEREERRAEEEQLQSCKGHETEEFP-DEEQLRRRELLELRRKGREEKQQQ 229
Query: 257 LLAERKRAYEAHDENK------VLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKE 310
+ R ++ +E + VL+KE ++L + +++REL + +L + +E
Sbjct: 230 RRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRE 289
Query: 311 KELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQS 370
++ + Q + + E+ K EE + +
Sbjct: 290 RQ------------------EEEQQQQRLRREQQ---------LRRKQEE------ERRE 316
Query: 371 QKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLER 430
Q+++R + ER E+ E + +++ E+ E + RE+ +++++++ +
Sbjct: 317 QQEERREQ-------QERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQE 369
Query: 431 EEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQ 479
EE+ E + R Q Q + Q E++L+RE L + ++ RE Q
Sbjct: 370 EERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 418
Score = 51.6 bits (122), Expect = 2e-06
Identities = 87/397 (21%), Positives = 157/397 (39%), Gaps = 42/397 (10%)
Query: 118 EVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRK 177
E SE Q +L + ++ + + + RQE + AE E Q H E +E+LR+
Sbjct: 153 EQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRR 212
Query: 178 -------------SQEKERATEKRVKDTESE---------LFRTKFSLQKLKEISEARHL 215
Q++ R + RV E E L + + LQ+ +E R L
Sbjct: 213 RELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQE-EEPQRQREL 271
Query: 216 PERDDLAKKLVSAELKLDDTE--------RRIKELSKNLELSTNSFQ--RQLLAERKRAY 265
E ++ +KL EL+ + E RR ++L + E Q R+ ER+
Sbjct: 272 QEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQ 331
Query: 266 EAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDF 325
E E ++ +++ +R +L+ ++ E +L + + +E LR+ + +
Sbjct: 332 EERREQQLRREQEERREQQLRREQEE----ERREQQLRREQEEERREQQLRREQQLRRE- 386
Query: 326 ADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPI 385
L + E E L E + E + L + + ++ ++ E
Sbjct: 387 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQR 446
Query: 386 MEREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLEREEKPEWETGRYQLGM 445
++RE+ +E +K+E E E ER + K+ ++ ER K E E R Q
Sbjct: 447 LKREQ----EERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQER 502
Query: 446 YPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQDSR 482
Q + + E+RLKR+ +L + R Q R
Sbjct: 503 REQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLR 539
Score = 48.5 bits (114), Expect = 2e-05
Identities = 79/406 (19%), Positives = 165/406 (40%), Gaps = 53/406 (13%)
Query: 114 ELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKE 173
+L+ E E Q+ E ++ + ++ RQE+ ED Q + R + +E
Sbjct: 1562 QLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMED-----EQQLRRQEGQQQLRQE 1616
Query: 174 RLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPE----RDDLAKKLVSAE 229
R RK +E E+ ++R E +L R + + L+E + R R D +K E
Sbjct: 1617 RDRKFREDEQLLQER---EEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEE 1673
Query: 230 LKLDDTER---RIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLK 286
L + E R +E + +RQ ER+R + +E ++ ++E++R + + +
Sbjct: 1674 QLLQEGEEQQLRRQERDRKFREEEQQLRRQ---ERERKF-LQEEQQLRRQELERKFREEE 1729
Query: 287 EKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPL 346
+ +E + + + + +E+ R+ + D + + + + E+
Sbjct: 1730 QLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLR 1789
Query: 347 TPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVE 406
+ E+ + K+ E L + + Q+ L P +R+ K+ +EE ++++ +
Sbjct: 1790 SQES----DRKFREEEQLRQEREEQQ---------LRP-QQRDGKYRWEEEQLQLEEQEQ 1835
Query: 407 KLEDEWEREELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREM 466
+L E +R+ ++Q REE+ W +EEE+ +R+
Sbjct: 1836 RLRQERDRQYRAEEQFATQEKSRREEQELW--------------------QEEEQKRRQE 1875
Query: 467 LLAKLNEIDRELQDSRNLKYPVLPLLPDFESKLHSPERSPKTYRFS 512
KL E Q ++ + + E K H P T++F+
Sbjct: 1876 RERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGRLLEPGTHQFA 1921
Score = 43.1 bits (100), Expect = 9e-04
Identities = 57/261 (21%), Positives = 116/261 (44%), Gaps = 46/261 (17%)
Query: 223 KKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLY 282
K+ + + + ++ +RR + + LE +RQ E++R +E Q E Q
Sbjct: 106 KESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEE----QSEKQ--- 158
Query: 283 HKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPE 342
+L++++R+ + ++ R +E R+ + + C KG +T E+F P+
Sbjct: 159 ERLEQRDRQRRDEELWRQR---------QEWQEREERRAEEEQLQSC-KGHET-EEF-PD 206
Query: 343 EYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVK 402
E L ++ K E + Q Q+++R E EEK E + K
Sbjct: 207 EEQLRRRELLELRRKGRE------EKQQQRRERQDRV-----FQEEEEKEWRKRETVLRK 255
Query: 403 QEVEKLEDEWEREELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERL 462
+E + E+E +R+ ++++E+ LER+E ++ + + ++++RL
Sbjct: 256 EEEKLQEEEPQRQRELQEEEEQLRKLERQE---------------LRRERQEEEQQQQRL 300
Query: 463 KREMLLAKLNEID-RELQDSR 482
+RE L + E + RE Q+ R
Sbjct: 301 RREQQLRRKQEEERREQQEER 321
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 70.9 bits (172), Expect = 4e-12
Identities = 102/441 (23%), Positives = 193/441 (43%), Gaps = 50/441 (11%)
Query: 82 GFRSQSLNRE--PLRKDTDLVTKRILSARLL--KINELQNEVSELQVKLAELLKENKSLK 137
G R++ L E L K+ +L+ K+I + ++ KI L+ E SEL+ + +L K S K
Sbjct: 624 GERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFK 683
Query: 138 RLQYRQEKALNKFEDAENEISQLIFRHNNE---ITALKERLRKSQEKERATEKRVKDTES 194
L ++ E +L K E+++ + L R N E ++K + + KE +EK
Sbjct: 684 NLTFQLE-SLEK-ENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGL 741
Query: 195 ELFRTKFSLQKLKEIS------EARHLPER-DDLAKKLVSAELKLDDTERRIKELSKNLE 247
EL + F + E+S E + L + ++ KK+ E +L D E + L KNLE
Sbjct: 742 ELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLE 801
Query: 248 -LSTNSFQRQLLAERKRAYEAHD-----ENKVLQKEVQRLYHKLKEKERELDIKNIYSNR 301
L +S + + L + ++ E + K L+KE +RL + + K+ L+ N+
Sbjct: 802 ELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGN 861
Query: 302 LPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEP 361
L K + KE+ + K + + + K + + E ++ + K ++
Sbjct: 862 LEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQM 921
Query: 362 GH----LTLDLQ----SQKQDRHGEAGILN--PIMEREEKFVTDEELHVVKQEVEKLEDE 411
+ LT +L+ ++++ H E + ++E + + + L + ++++ LE
Sbjct: 922 NNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEAR 981
Query: 412 WE---------REELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERL 462
E R+EL +K +L +R+++ R PI D E +
Sbjct: 982 LEESTNYNQQLRQELKTVKKNYEALKQRQDEE-----RMVQSSPPISGEDNKWERESQET 1036
Query: 463 KREMLLAKLNEIDRELQDSRN 483
RE+L K DR ++ RN
Sbjct: 1037 TRELLKVK----DRLIEVERN 1053
Score = 57.8 bits (138), Expect = 3e-08
Identities = 97/412 (23%), Positives = 181/412 (43%), Gaps = 69/412 (16%)
Query: 85 SQSLNREPLRKDTDLVTKRILSARLLKINELQNE-----VSEL--------QVKLAELLK 131
S+ L +E + + + T R S R +KI E +NE VS L + ++ ++ K
Sbjct: 528 SKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEK 587
Query: 132 ENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKD 191
ENK L L+K E + +I + E+ KE+ +++E E E +
Sbjct: 588 ENKILHESIKETSSKLSKIEFEKRQIKK-------ELEHYKEKGERAEELE--NELHHLE 638
Query: 192 TESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTN 251
E+EL + K + K+ +K+ + E + + ER ++L K L+ S
Sbjct: 639 KENELLQKKITNLKI--------------TCEKIEALEQENSELERENRKLKKTLD-SFK 683
Query: 252 SFQRQLLAERKRAYEAHDENKVLQKEVQRL-YHKLKEKERELDIKNIYSNRLPKSSPNKE 310
+ QL + K + +EN L++ V+ L +K + +L+ K + S + +
Sbjct: 684 NLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEK-----EQLK 738
Query: 311 KELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQS 370
K L L K + +++ ++ +G+ D + + T E NK + L+S
Sbjct: 739 KGLELLKASFKKTERLEVSYQGL----DIENQRLQKTLEN----SNKKIQ------QLES 784
Query: 371 QKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLER 430
+ QD E L + EE ++ + L +++E + LE E + E DKKQ EK + R
Sbjct: 785 ELQDLEMENQTLQKNL--EELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLR 842
Query: 431 EEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAK-----LNEIDRE 477
++ E + + I N++K E + L +E+ + K L E+++E
Sbjct: 843 QQ-AEIKDTTLEENNVKIGNLEK----ENKTLSKEIGIYKESCVRLKELEKE 889
Score = 51.6 bits (122), Expect = 2e-06
Identities = 105/462 (22%), Positives = 203/462 (43%), Gaps = 87/462 (18%)
Query: 91 EPLRKDTDLV--TKRILS-------ARLLKINELQNEVSELQVKL--------------A 127
E L++D ++ TK +L AR K++EL+ E +L+ KL
Sbjct: 347 EELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIE 406
Query: 128 ELLKENKSLKRLQYR-QEKALNKFEDAE--------NEISQLIFRHN-NEITALK----- 172
EL++EN +L+ Q + +++L+ + E +E Q H NE+T+ +
Sbjct: 407 ELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLE 466
Query: 173 ---ERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKE---------ISEARHLPERDD 220
+ L K+ E+ R T V+ S++ + + Q+L + + E + L +
Sbjct: 467 MENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQN 526
Query: 221 LAKKLVSAELKLDDT--------ERRIKEL---SKNLELSTNSF-QRQLLAERKRAYEAH 268
L+K L+ + +L+ T ER+IK L +++L + +S QR ++ R +
Sbjct: 527 LSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIE 586
Query: 269 DENKVLQKEVQRLYHKLKEKERE-LDIKNIYSNRLPKSSPNKEKELAL----RKNAACQS 323
ENK+L + ++ KL + E E IK + K +E E L ++N Q
Sbjct: 587 KENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQK 646
Query: 324 DFADL---CTKGVQTMEDFKPE---EYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHG 377
+L C K ++ +E E E +T+ ++N LT L+S +++ +
Sbjct: 647 KITNLKITCEK-IEALEQENSELERENRKLKKTLDSFKN-------LTFQLESLEKE-NS 697
Query: 378 EAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLEREEKPEWE 437
+ N + R + + + + + ++E E E E+E+L K + + ++ E+ E
Sbjct: 698 QLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVS 757
Query: 438 TGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQ 479
YQ G+ I+N + E K + L ++L +++ E Q
Sbjct: 758 ---YQ-GL-DIENQRLQKTLENSNKKIQQLESELQDLEMENQ 794
Score = 49.3 bits (116), Expect = 1e-05
Identities = 87/383 (22%), Positives = 161/383 (42%), Gaps = 53/383 (13%)
Query: 85 SQSLNREPLRKDTDLVTKRILSARLLKINELQNE-VSELQVKLAELLKENKSLKRLQYRQ 143
++SL +E + + D + RL + E+++ + E VK+ L KENK+L +
Sbjct: 817 NKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIY 876
Query: 144 EKALNKFEDAENEISQLIFRHNNEI---TALKERLRKSQEKERATEKRVKDTESELFRTK 200
+++ + ++ E E +L+ R +I L+E L + K + ++ EL K
Sbjct: 877 KESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHEL--EK 934
Query: 201 FSLQKLKEISEARHLPERDDLAKKLVSAELK--LDDTERRIKELSKNLELSTNSFQ--RQ 256
L K + + + + +R L + + + LK L+ E +I L LE STN Q RQ
Sbjct: 935 IGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQ 994
Query: 257 LLAERKRAYEA----HDENKVLQ----------------KEVQRLYHKLKEKERELDIKN 296
L K+ YEA DE +++Q +E R K+K++ E++ N
Sbjct: 995 ELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNN 1054
Query: 297 IYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYEN 356
++ + K+L + N Q+ L + V E T + +N
Sbjct: 1055 ATLQAEKQALKTQLKQLETQNN-NLQAQILALQRQTVSLQEQ----------NTTLQTQN 1103
Query: 357 KWEEPGHLTLDLQSQK-QDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWERE 415
+ + TL+ QS +++ + I +E E + V E +++++ L D
Sbjct: 1104 AKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKE-----REDLKSLYDSL--- 1155
Query: 416 ELDKKQKEKASLLEREEKPEWET 438
K EK LL + E+E+
Sbjct: 1156 ---IKDHEKLELLHERQASEYES 1175
Score = 40.0 bits (92), Expect = 0.007
Identities = 50/231 (21%), Positives = 97/231 (41%), Gaps = 37/231 (16%)
Query: 105 LSARLLKINE----LQNEVSELQVKLAELLKENKSLKR----LQYRQEKALNKFEDAENE 156
L A++L + LQ + + LQ + A+L EN +L L + + L + ENE
Sbjct: 1078 LQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENE 1137
Query: 157 ISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLP 216
++ + + ++ +L + L K EK +R L +L+ + E H
Sbjct: 1138 -NESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHR- 1195
Query: 217 ERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQ------RQLLAERKRAYEAHD- 269
+ +D +L+ + +L+D E+ +K + + L + + ++L E R +
Sbjct: 1196 DLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQ 1255
Query: 270 ---ENKVLQKEVQRL-----------------YHKLKEKERELDIKNIYSN 300
E +VLQ + + L + KLKE+ ++LDI + N
Sbjct: 1256 LLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLN 1306
>gi|118498362 kinectin 1 isoform b [Homo sapiens]
Length = 1306
Score = 68.9 bits (167), Expect = 1e-11
Identities = 83/417 (19%), Positives = 191/417 (45%), Gaps = 35/417 (8%)
Query: 99 LVTKRILSARLLKINELQ----NEVSELQVKLAELLKENKSLK-RLQ--YRQEKALNKFE 151
LV+K+ L RL+++ E + N+ LQ+++ ++L++N++LK ++Q + Q A
Sbjct: 540 LVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSAS 599
Query: 152 DAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISE 211
E+ ++I + +I ++ L +++ + E+ +KD ++ F K +QKL+
Sbjct: 600 VLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQA--- 656
Query: 212 ARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDEN 271
LA + +A +L+ ++ + + L Q ++ + + +D+N
Sbjct: 657 ---------LANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQN 707
Query: 272 KVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTK 331
K L+ EVQ+L + E+ + ++ ++ K K+++L + ++ + TK
Sbjct: 708 KALKSEVQKLQTLVSEQPNKDVVE-----QMEKCIQEKDEKLKTVEE-LLETGLIQVATK 761
Query: 332 GVQTMEDFKPEEYPLTPET--IMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMERE 389
+ + + E LT E + +N L +L+ ++ G+ + ++E E
Sbjct: 762 -EEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAE 820
Query: 390 EKFVTDEELHV---VKQEVEKLEDEWEREELDKKQKEKASLLEREEKPEWETGRYQLGMY 446
V ++E V + +V++L++ + +E ++ ++LE +EK TG++ +
Sbjct: 821 LLKVANKEKTVQLSITSKVQELQNLLKGKE--EQMNTMKAVLEEKEKDLANTGKWLQDLQ 878
Query: 447 PIQNMDKLQGEE--EERLKREMLLAKLNEIDRELQDSRNLKYPVLPLLPDFESKLHS 501
K +E + LK ++ E++ L++ N + +L + ES L S
Sbjct: 879 EENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSS 935
Score = 42.7 bits (99), Expect = 0.001
Identities = 84/428 (19%), Positives = 186/428 (43%), Gaps = 48/428 (11%)
Query: 110 LKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEIT 169
+++ E + E+Q + + E+++ Q+ +KF ENE+ L + + +
Sbjct: 488 VQLQEAERRWEEVQSYIRKRTAEHEAA------QQDLQSKFVAKENEVQSLHSKLTDTLV 541
Query: 170 A---LKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEA--RHLPERDDLAKK 224
+ L++RL + E E +KRV ES + +Q + E +EA + +
Sbjct: 542 SKQQLEQRLMQLMESE---QKRVNKEES----LQMQVQDILEQNEALKAQIQQFHSQIAA 594
Query: 225 LVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHK 284
SA + ++ + I E K ++ + +S L +ER R +E K++Q +
Sbjct: 595 QTSASVLAEELHKVIAEKDKQIKQTEDS----LASERDRLTSKEEE----LKDIQNMNFL 646
Query: 285 LKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEY 344
LK + ++L +N ++ EK ++++ + D L + +Q K EE+
Sbjct: 647 LKAEVQKL---QALANEQAAAAHELEK---MQQSVYVKDDKIRLLEEQLQHEISNKMEEF 700
Query: 345 PLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQE 404
+ + +++ ++ L S++ ++ + I E++EK T EEL E
Sbjct: 701 KILNDQNKALKSEVQK----LQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEEL----LE 752
Query: 405 VEKLEDEWEREELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERLK- 463
++ + EEL+ + E +SL + + + + ++ + K+ E++ ++K
Sbjct: 753 TGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKS 812
Query: 464 -REMLLAKLNEIDRELQDSRNLKYPVLPLLPDFESKLHSPERSPKTYR--FSESSERLFN 520
E+L A+L ++ + + ++ + + + ++ L E T + E + L N
Sbjct: 813 VEELLEAELLKVANK---EKTVQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLAN 869
Query: 521 -GHHLQDI 527
G LQD+
Sbjct: 870 TGKWLQDL 877
Score = 42.0 bits (97), Expect = 0.002
Identities = 45/213 (21%), Positives = 98/213 (46%), Gaps = 21/213 (9%)
Query: 79 VRVGFRSQSLNREPLRKDTDLVTKRILSARLLKINELQNEVSELQVKLAELLKENKSLKR 138
++V + + LN +R + +TK + + QN+ QV A L++E K +
Sbjct: 756 IQVATKEEELNA--IRTENSSLTKEVQD-----LKAKQND----QVSFASLVEELKKVIH 804
Query: 139 LQYRQEKALNKFEDAE-----NEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTE 193
+ + K++ + +AE N+ + +++ L+ L+ +E+ + +++ E
Sbjct: 805 EKDGKIKSVEELLEAELLKVANKEKTVQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKE 864
Query: 194 SELFRTKFSLQKLKEISEA--RHLPERDDLAKKLVSAELKLDDTERRIKELS---KNLEL 248
+L T LQ L+E +E+ H+ E K S+ + ++ E +KE K LE
Sbjct: 865 KDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEA 924
Query: 249 STNSFQRQLLAERKRAYEAHDENKVLQKEVQRL 281
+ L ++ + + DENK+ + ++++L
Sbjct: 925 MLKERESDLSSKTQLLQDVQDENKLFKSQIEQL 957
Score = 35.0 bits (79), Expect = 0.24
Identities = 81/382 (21%), Positives = 144/382 (37%), Gaps = 77/382 (20%)
Query: 103 RILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKAL----NKFEDAENEIS 158
+++S R +I+ L NE+ L+ + K+N L+ + +AL +D N+ S
Sbjct: 976 KVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTS 1035
Query: 159 QLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPE- 217
KER Q++ A E K+ +LF K S+ E H E
Sbjct: 1036 -------------KER----QQQVEAVELEAKEVLKKLF-PKVSVPSNLSYGEWLHGFEK 1077
Query: 218 --RDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQ 275
++ +A S E+K+ E ++KE + L QL E+ ++ A E +LQ
Sbjct: 1078 KAKECMAGTSGSEEVKV--LEHKLKEADEMHTL------LQLECEKYKSVLAETEG-ILQ 1128
Query: 276 KEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQT 335
K L ++++E + +K S++ K QS F T Q
Sbjct: 1129 K----LQRSVEQEENKWKVKVDESHKTIKQ---------------MQSSF----TSSEQE 1165
Query: 336 MEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPI---------- 385
+E + E + EN E HL ++L+ + +R + +
Sbjct: 1166 LERLRSENKDI--------ENLRREREHLEMELEKAEMERSTYVTEVRELKAQLNETLTK 1217
Query: 386 --MEREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLEREEKPEWETGRYQL 443
E+ E+ +LH +Q +E ++ + + D E + + E E ET L
Sbjct: 1218 LRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVSL 1277
Query: 444 GMYPIQNMDKLQGEEEERLKRE 465
Q LQ ++ K +
Sbjct: 1278 NQTVTQLQQLLQAVNQQLTKEK 1299
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 68.9 bits (167), Expect = 1e-11
Identities = 91/418 (21%), Positives = 182/418 (43%), Gaps = 57/418 (13%)
Query: 114 ELQNEVSELQVKLAELLKENKSL--------KRLQYRQEKALNKFEDAENEISQL----- 160
EL ++V +L K+ L KE S + ++KA ++F +N + +L
Sbjct: 1409 ELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLE 1468
Query: 161 -----IFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHL 215
+ + +I LKE L + ++ + ++D +S++ + + +L+ + AR +
Sbjct: 1469 LKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIM 1528
Query: 216 PERDDLAKKLVSAE-----LKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDE 270
D + +K + E LK + ++ I+ K L FQ + R EA ++
Sbjct: 1529 ELEDHITQKTIEIESLNEVLKNYNQQKDIEH--KELVQKLQHFQELGEEKDNRVKEAEEK 1586
Query: 271 NKVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCT 330
L+ +V + +L+ K++EL+ + N KS + K L R + + A+L
Sbjct: 1587 ILTLENQVYSMKAELETKKKELE----HVNLSVKSKEEELKALEDRLESESAAKLAELKR 1642
Query: 331 KGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREE 390
K Q + K + E Y+ E HL+ +L ++ Q+R E IL ++ E
Sbjct: 1643 KAEQKIAAIKKQLLSQMEEKEEQYKKGTE--SHLS-ELNTKLQEREREVHILEEKLKSVE 1699
Query: 391 KFVTDEELHVVKQEVEKLEDEWEREELD------KKQKEKASLLER-------------E 431
+ E +V + + + E+EE D K +EK S+L+R +
Sbjct: 1700 S--SQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQ 1757
Query: 432 EKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQDSRNLKYPVL 489
EK E + +++ + + KL+ E ++ + + ++ L E EL++ +N KY ++
Sbjct: 1758 EKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQE---ELEE-KNKKYSLI 1811
Score = 54.3 bits (129), Expect = 4e-07
Identities = 109/459 (23%), Positives = 190/459 (41%), Gaps = 69/459 (15%)
Query: 95 KDTDLVTKRILSARLLKINELQNE-------VSELQVKLAELLKENKS-LKRLQYRQEKA 146
++ +L K IL+ K+ +LQ E + EL+ L + L+ENK+ K L E
Sbjct: 538 EELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAE 597
Query: 147 LNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKF----- 201
NK EI+ ++ +H E+ +LK + ++ K+ TE E R K
Sbjct: 598 KNKH---NKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKE 654
Query: 202 SLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNL--------ELS---- 249
+L K KEI H+ E ++ K L ++K + E ELS+ L ELS
Sbjct: 655 TLLKDKEIIFQAHIEEMNE--KTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKD 712
Query: 250 -TNSFQRQLLAERKRAYEAHDE----------------NKVLQKEVQRLYHKLKEKEREL 292
T+ +++L A+ H + K L+ ++ +L LKE+++ L
Sbjct: 713 QTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHL 772
Query: 293 DIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIM 352
+ L E EL + A+ + D E+ + ++
Sbjct: 773 KEHQAHVENLEADIKRSEGEL---QQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLL 829
Query: 353 CYENKWEEPGHLTLDLQSQKQDRHGEAGI----LNPIMEREEKFVTDEELHV--VKQEVE 406
E + ++++QK+D E + +M++ EK ++ E V + Q E
Sbjct: 830 DLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYE 889
Query: 407 -KLEDEWEREELDKK---QKEKASLLERE-EKPEWETGRYQLGMYPIQNMDKLQGEEEER 461
KLED + +E K+ +KE L RE +K E E +L ++ L E E +
Sbjct: 890 SKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKE-DSIHILNEEYETK 948
Query: 462 LK-REMLLAKLNEIDRELQDSRNLKYPVLPLLPDFESKL 499
K +E + K+ + +E+Q++ K L D E+KL
Sbjct: 949 FKNQEKKMEKVKQKAKEMQETLKKK------LLDQEAKL 981
Score = 53.5 bits (127), Expect = 6e-07
Identities = 74/354 (20%), Positives = 154/354 (43%), Gaps = 37/354 (10%)
Query: 90 REPLRKDTDLV----TKRILSARLLKINELQNEVSELQVKLAELLKENKSLKR-LQYRQE 144
+E L KD +++ + + L K++ Q E+ L +L+E+LK L+ L ++
Sbjct: 653 KETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKD 712
Query: 145 KALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQ 204
+ ++ E ++ + H ++ ++ +++ + + TEK +KD ++L
Sbjct: 713 QTDKMKQELEAKMDEQKNHHQQQVDSI---IKEHEVSIQRTEKALKDQINQLELL----- 764
Query: 205 KLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLEL----------STNSFQ 254
LKE +HL E + L E + +E +++ S L++ T +++
Sbjct: 765 -LKE--RDKHLKEHQAHVENL---EADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYE 818
Query: 255 RQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELA 314
QL +++ + E +L K+V + + K+ ELD I L + + E+
Sbjct: 819 EQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEME 878
Query: 315 LRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQD 374
+ + Q + G + E K + E + +E LT L +++
Sbjct: 879 QKVKSLTQV-YESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDS 937
Query: 375 RHGEAGILNPIMEREEKFVTDE-ELHVVKQEVEKLEDEWEREELDKKQKEKASL 427
H ILN E E KF E ++ VKQ+ +++++ +++ LD++ K K L
Sbjct: 938 IH----ILNE--EYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKEL 985
Score = 50.1 bits (118), Expect = 7e-06
Identities = 113/524 (21%), Positives = 201/524 (38%), Gaps = 87/524 (16%)
Query: 31 QSSGRSSLVSSSPASVRRKNPKRQTSDGQVHHQAPRKPSPKGLPNRKGVRVGFRSQSLNR 90
+SS + SLV +S R++ R D P P + + VG S SLN+
Sbjct: 86 RSSSKESLVRTSS----RESLNRLDLDSSTASFDP----PSDMDSEAEDLVG-NSDSLNK 136
Query: 91 EPLRKDTDLVTKRILSARLLKINELQNEVSELQVKLAELLKENKSLKR-LQYRQEKALNK 149
E L + + + + S R + SEL L +E K L+ L Q+K+L +
Sbjct: 137 EQLIQRLRRMERSLSSYR--------GKYSELVTAYQMLQREKKKLQGILSQSQDKSLRR 188
Query: 150 FEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLK-- 207
+ E+ + ++ +K ++E KD + +T+ SL K +
Sbjct: 189 IAELREELQ------------MDQQAKKHLQEEFDASLEEKDQYISVLQTQVSLLKQRLR 236
Query: 208 ----EISEARHLPERDDLAKKLVSAELKLDDTERRIKELS--KNLELSTNSFQRQ--LLA 259
+ + LP+ + A+ E D E +++ + K LE +RQ LL
Sbjct: 237 NGPMNVDVLKPLPQLEPQAEVFTKEENPESDGEPVVEDGTSVKTLETLQQRVKRQENLLK 296
Query: 260 ERKRAYEAHDEN-KVLQKEVQRLYHKLKEKERELD-IKNIY--------------SNRLP 303
K ++H E +L E + L +L E+ +EL+ IK+++ N +
Sbjct: 297 RCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIE 356
Query: 304 KSSPNKEKELALRKN-------------AACQSDFADLCTKGVQTMEDFKPEEYPLTPET 350
+ +K +A K A +S + T+G + E + E E
Sbjct: 357 QLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEEL 416
Query: 351 IMCYENKWE-EPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLE 409
+ E L + +Q + E EE+ +EL VKQEV +
Sbjct: 417 EKALSTAQKTEEARRKLKAEMDEQIKTIEK------TSEEERISLQQELSRVKQEVVDVM 470
Query: 410 DEWEREELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLA 469
+ E++ K QK L R+E+ + + + + Q L+ + E LK
Sbjct: 471 KKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQ--- 527
Query: 470 KLNEIDRELQDS---RNLKYPVLPLLPDFESKLHSPERSPKTYR 510
++E Q+S L+ +L + E+KL ++ +TYR
Sbjct: 528 -----EKEQQESLALEELELQKKAILTESENKLRDLQQEAETYR 566
Score = 46.2 bits (108), Expect = 1e-04
Identities = 101/445 (22%), Positives = 187/445 (42%), Gaps = 74/445 (16%)
Query: 111 KINELQNEV----SELQVKLAELLKENKSLKRLQYRQEKALNKFEDAEN--EISQLIFRH 164
KI L+N+V +EL+ K EL N S+K + + KAL ++E+ ++++L +
Sbjct: 1586 KILTLENQVYSMKAELETKKKELEHVNLSVKSKE-EELKALEDRLESESAAKLAELKRKA 1644
Query: 165 NNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKK 224
+I A+K++L E++ E+ K TES L KL+E H+ L +K
Sbjct: 1645 EQKIAAIKKQLLSQMEEKE--EQYKKGTESHLSELN---TKLQEREREVHI-----LEEK 1694
Query: 225 LVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHK 284
L S E +T + +KN+ T E++ A K ++++ L
Sbjct: 1695 LKSVESSQSET-LIVPRSAKNVAAYT---------EQEEADSQGCVQKTYEEKISVLQRN 1744
Query: 285 LKEKEREL-----DIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDF 339
L EKE+ L + + S+ +E+ + L A Q + + + +E+
Sbjct: 1745 LTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEE- 1803
Query: 340 KPEEYPLTPETIMCYENKWEEPGHLTL-----------DLQSQKQDRHGEAGIL-NPIME 387
K ++Y +++ ++ +E G + D+Q Q++ IL I E
Sbjct: 1804 KNKKY-----SLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKE 1858
Query: 388 REEKFVTDEELHVVKQEVEKLEDEWER----EELDKKQKEKASLLEREEKPEWETGRYQL 443
+ V +E+H V E+E+L ++E+ +++D + K L EE E ++ + +
Sbjct: 1859 LDSCLVRQKEVHRV--EMEELTSKYEKLQALQQMDGRNKPTELL---EENTEEKSKSHLV 1913
Query: 444 GMYPIQNMD--------KLQGEEEERLKREMLLAKLNEIDRELQDSRNLKYPVLPLLPDF 495
+ NM+ KL G E E+ K + +L + R L+ + +L
Sbjct: 1914 QPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEIL------ 1967
Query: 496 ESKLHSPERSPKTYRFSESSERLFN 520
K + ER K + E E N
Sbjct: 1968 -KKEYDQEREEKIKQEQEDLELKHN 1991
Score = 42.7 bits (99), Expect = 0.001
Identities = 99/525 (18%), Positives = 200/525 (38%), Gaps = 62/525 (11%)
Query: 116 QNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERL 175
+ ++++LQ KL +L E L K + + E + ++ + H ++ L ++L
Sbjct: 818 EEQLAQLQQKLLDLETERILLT-------KQVAEVEAQKKDVCTELDAHKIQVQDLMQQL 870
Query: 176 RK-SQEKERATEKRVKDTESELFRTKFSLQKLKEI---SEARHLPERDDLAKKLVSAELK 231
K + E E+ + + ES+L ++ K+I E L R+ K++ K
Sbjct: 871 EKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQK 930
Query: 232 LDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAH--------DENKVLQKEVQRLYH 283
L E I L++ E + ++++ +++A E D+ L+KE++
Sbjct: 931 LSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTAL 990
Query: 284 KLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEE 343
+L +KE++ + K + E+A +A + L T + +E
Sbjct: 991 ELSQKEKQFNAKML--------------EMAQANSAGISDAVSRLETNQKEQIESLTEVH 1036
Query: 344 YPLTPETIMCYENKWEEPGHLTLDL-QSQKQDRHGEAGILNP--IMEREEKFVTDEELHV 400
+ I +E K + ++ + Q Q++ E L ++ EK ++E+
Sbjct: 1037 RRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITW 1096
Query: 401 VKQEVEKLEDEWE--REELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGE- 457
+K+E K + +E+L +K SL + E K + + ++ + + E
Sbjct: 1097 LKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQ 1156
Query: 458 --------EEERLKREMLLAKLNEIDRELQDSRNLKYPVLPLLPD--FESKLHSPERSPK 507
EE++ K L +KL D E Q ++ L D E K S E + +
Sbjct: 1157 LVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQ 1216
Query: 508 TYRFSESSERLFNGHHLQDISFSTPKGEG---------QNSGNVRSPASPNEFAFGSYVP 558
+ +E L + I+ S+ K + V+
Sbjct: 1217 LDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEA 1276
Query: 559 SFAKTSERSN----PFSQKSSFLDFQRNSMEKLSKDGVDLITRKE 599
+ +E N F Q + L+ + N ++ + D L+T KE
Sbjct: 1277 QLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKE 1321
Score = 40.8 bits (94), Expect = 0.004
Identities = 88/448 (19%), Positives = 185/448 (41%), Gaps = 39/448 (8%)
Query: 88 LNREPLRKDTDL-VTKRILSARLLKINELQNEVSELQVKLAELLKE-NKSLKRLQYRQEK 145
L E +++DT L + L + +N L + ++L+ L +L + NKSLK + QE+
Sbjct: 1097 LKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQ 1156
Query: 146 ALNK---FEDAENEISQLIFR---HNNEITALKERLRKSQEKERATEKRVKDTESEL-FR 198
+ E+ + ++S+L + + E +LK KS + K EL +
Sbjct: 1157 LVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQ 1216
Query: 199 TKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLL 258
+K + + EA+ + + K + ++ + R ++ + L + T + +L
Sbjct: 1217 LDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVS-ELE 1275
Query: 259 AERKRAYEAHDENKVLQKEVQRLYHKLKEKEREL-----DIKNIYSNRLPKSSPNKEKEL 313
A+ ++ E E L Q+ H+L+EKE ++ DI+++ + + ++
Sbjct: 1276 AQLRQLTE---EQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQ 1332
Query: 314 ALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQ 373
A + +C + ++ + + K E E + + ++ L + LQ+
Sbjct: 1333 AASEKESCITQLKKELSENINAVTLMKEE----LKEKKVEISSLSKQLTDLNVQLQNSIS 1388
Query: 374 DRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLEREEK 433
EA I + + DEE + +V+ L ++D KEK S LE+ +
Sbjct: 1389 LSEKEAAISSLRKQ------YDEEKCELLDQVQDLS-----FKVDTLSKEKISALEQVDD 1437
Query: 434 -----PEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQDSRNLKYPV 488
EW+ + +LQ + E + K + + +E D +N ++
Sbjct: 1438 WSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDC 1497
Query: 489 LP-LLPDFESKLHSPERSPKTYRFSESS 515
L + D +SK+ E + +T S+++
Sbjct: 1498 LKGEMEDDKSKMEKKESNLETELKSQTA 1525
Score = 38.9 bits (89), Expect = 0.016
Identities = 63/316 (19%), Positives = 138/316 (43%), Gaps = 25/316 (7%)
Query: 108 RLLKINELQNEVSELQVK-LAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNN 166
+ L+ EL ++ E ++K L L K + R++ E+ +K+E + Q + N
Sbjct: 1840 KTLQEKELTCQILEQKIKELDSCLVRQKEVHRVE--MEELTSKYEKLQ--ALQQMDGRNK 1895
Query: 167 EITALKERLRKSQEKERATEKRVKDTESELFRTKFSL-----QKLKEISEARHLPERDDL 221
L+E + + K + + E++ +F L +K K E L + +
Sbjct: 1896 PTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRM 1955
Query: 222 AKKLVSAELKL------DDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQ 275
+K EL++ + E +IK+ ++LEL NS +QL+ E + + + L+
Sbjct: 1956 LRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNT--QLAQKEQELE 2013
Query: 276 KEVQRLYHKLKEKERE-LDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQ 334
++ +K +E E E L+ +N+L K K+ + L++ A + D + +
Sbjct: 2014 MTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDD--LKRTAKRYEEILDAREEEMT 2071
Query: 335 T-MEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFV 393
+ D + + L + E + E PG+ + + + + +++ +E++F
Sbjct: 2072 AKVRDLQTQLEELQKKYQQKLEQE-ENPGNDNVTIMELQTQLAQKTTLISDSKLKEQEF- 2129
Query: 394 TDEELHVVKQEVEKLE 409
E++H ++ ++K E
Sbjct: 2130 -REQIHNLEDRLKKYE 2144
Score = 34.3 bits (77), Expect = 0.40
Identities = 88/378 (23%), Positives = 145/378 (38%), Gaps = 73/378 (19%)
Query: 116 QNEVSELQVKLAELLKENKSLKRL-QYRQEKALNKFEDAENEISQLIFRHNNEITALKER 174
+ ++S LQ L E + K L+R+ Q ++E + FE +LI + E +++
Sbjct: 1735 EEKISVLQRNLTE---KEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQ 1791
Query: 175 LRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPER--DDLAKKLVSAELKL 232
+E EK K S + + K +A+ E DD+ K L EL
Sbjct: 1792 SMIGHLQEELEEKNKK--YSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTC 1849
Query: 233 DDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKEREL 292
E++IKEL L R E H +V +E+ Y KL+ + ++
Sbjct: 1850 QILEQKIKELDSCL---------------VRQKEVH---RVEMEELTSKYEKLQALQ-QM 1890
Query: 293 DIKNIYSNRLPKSSPNKEK----ELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTP 348
D +N + L +++ K K + L N Q + + G + E+ L
Sbjct: 1891 DGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAER------EKQKLGK 1944
Query: 349 ETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNP--IMEREEKFVTDEELHVVKQEVE 406
E + L DL+ +++ E IL EREEK +KQ
Sbjct: 1945 EIV-----------RLQKDLRMLRKEHQQELEILKKEYDQEREEK---------IKQ--- 1981
Query: 407 KLEDEWEREELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERL---- 462
E+E+L+ K L RE + +L M + ++K Q E E L
Sbjct: 1982 ------EQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQ 2035
Query: 463 -KREMLLAKLNEIDRELQ 479
+ LL K+ E D +L+
Sbjct: 2036 EETNQLLKKIAEKDDDLK 2053
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 67.0 bits (162), Expect = 6e-11
Identities = 74/355 (20%), Positives = 163/355 (45%), Gaps = 28/355 (7%)
Query: 111 KINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITA 170
KI E + ++ E + K+ E ++ + + RQE+ + + E+ ++++ ++
Sbjct: 369 KIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR 428
Query: 171 LKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAEL 230
+E + + +EK R E+++ + E + + +K +E + R +R + K+ E
Sbjct: 429 QEEMMWEKEEKIRELEEKMHEQE----KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 484
Query: 231 KLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKER 290
K+ + E +I+E + + Q + + E+++ E +E + Q+E+ R K++E+E
Sbjct: 485 KIREQEEKIREQEEKMWR-----QEEKIHEQEKIRE--EEKRQEQEEMWRQEEKIREQEE 537
Query: 291 ELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPET 350
K + K +EK + Q + + V E+ E+ E
Sbjct: 538 IWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQ----EEK 593
Query: 351 IMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLED 410
I E K E +T +++++ GE + E+EEK EE + +QE + E
Sbjct: 594 IREQEEKIREQEEMT----QEQEEKMGEQE--EKMCEQEEKMQEQEE-KMRRQEEKIREQ 646
Query: 411 EWEREELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKRE 465
E + E ++K +E+ +++ +E+ WE + +K+Q E+EE+++R+
Sbjct: 647 EKKIREQEEKIREQEEMMQEQEEKMWEQEEKM-----CEQEEKMQ-EQEEKMRRQ 695
Score = 53.9 bits (128), Expect = 5e-07
Identities = 85/446 (19%), Positives = 197/446 (44%), Gaps = 49/446 (10%)
Query: 35 RSSLVSSSPASVRRKNPKRQTSDGQVHHQAPRKPSPKGLPNRKGVRVGFRSQSLNREPLR 94
R S ++ + + +P+ S G +K G G S ++
Sbjct: 117 RQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASH 176
Query: 95 KDTDLVTKRILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAE 154
+ + + +R L A++ I L + +ELQ+ L ++K+L+ +++ D+
Sbjct: 177 QHQEAL-RRELEAQVHTIRILTCQKTELQMAL---YYSQHAVKQLEGEARDLISRLHDSW 232
Query: 155 NEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTES---ELFRTKFSLQKLKEISE 211
+L ++A+ + +K+ +R E+ K+ ++ EL+R + ++LKE
Sbjct: 233 KFAGEL----EQALSAVATQKKKA---DRYIEELTKERDALSLELYRNTITDEELKE--- 282
Query: 212 ARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDEN 271
+ L +KL E + + + +KEL + LE + + LL +++ EA
Sbjct: 283 -----KNAKLQEKLQLVESEKSEIQLNVKELKRKLERA-----KLLLPQQQLQAEADH-- 330
Query: 272 KVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTK 331
L KE+Q + KL+ + E ++ N + + + +E+++ + + + K
Sbjct: 331 --LGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE-----EK 383
Query: 332 GVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEK 391
+ E + +E + + M +E EE ++ +K+++ M R+E+
Sbjct: 384 IREQEEKIREQEEKMRRQEEMMWEK--EEKMRRQEEMMWEKEEK----------MRRQEE 431
Query: 392 FVTDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNM 451
+ ++E + + E + E E RE+ +K+Q+E+ + E+E++ E E ++ +
Sbjct: 432 MMWEKEEKIRELEEKMHEQEKIREQEEKRQEEE-KIREQEKRQEQEAKMWRQEEKIREQE 490
Query: 452 DKLQGEEEERLKREMLLAKLNEIDRE 477
+K++ +EE+ ++E + + +I E
Sbjct: 491 EKIREQEEKMWRQEEKIHEQEKIREE 516
Score = 39.7 bits (91), Expect = 0.010
Identities = 28/150 (18%), Positives = 72/150 (48%), Gaps = 13/150 (8%)
Query: 111 KINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITA 170
KI E + +V + K+ E ++ + + QE+ + E+ E + + ++
Sbjct: 572 KIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQE 631
Query: 171 LKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKE---------ISEARHLPERDDL 221
+E++R+ +EK R EK++++ E ++ + +Q+ +E + + E+++
Sbjct: 632 QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 691
Query: 222 AK----KLVSAELKLDDTERRIKELSKNLE 247
+ K+ E++L E +++E ++LE
Sbjct: 692 MRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 721
Score = 36.2 bits (82), Expect = 0.11
Identities = 23/163 (14%), Positives = 78/163 (47%), Gaps = 10/163 (6%)
Query: 111 KINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITA 170
K+++ + ++ E + K+ ++ + + QE+ + + E+ E + + ++
Sbjct: 565 KMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCE 624
Query: 171 LKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAEL 230
+E++++ +EK R E+++++ E ++ + +++ +E+ + + +K+ E
Sbjct: 625 QEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQE--------EKMWEQEE 676
Query: 231 KLDDTERRIKELSKNLELSTNSF--QRQLLAERKRAYEAHDEN 271
K+ + E +++E + + Q L +++ + H E+
Sbjct: 677 KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEH 719
Score = 33.5 bits (75), Expect = 0.68
Identities = 28/171 (16%), Positives = 80/171 (46%), Gaps = 4/171 (2%)
Query: 46 VRRKNPKRQTSDGQVHHQAP--RKPSPKGLPNRKGVRVGFRSQSLNREPLRKDTDLVTKR 103
+R++ K + ++H Q R+ K + +R E +R+ ++ ++
Sbjct: 552 IRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQ 611
Query: 104 I--LSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLI 161
+ + K+ E + ++ E + K+ ++ + ++ QE+ + + E+ E + +
Sbjct: 612 EEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 671
Query: 162 FRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEA 212
+ ++ +E++++ +EK R E+++ + E L + + +Q+ +E EA
Sbjct: 672 WEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 722
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 66.6 bits (161), Expect = 7e-11
Identities = 105/491 (21%), Positives = 202/491 (41%), Gaps = 76/491 (15%)
Query: 35 RSSLVSSSPASVRRKNPKRQTSDGQVHHQAPRKPSPKGLPNRKGVRVGFRSQSLNREPLR 94
R+S SS+ A + + + T Q+ Q + +++ F + + +
Sbjct: 252 RNSTHSSTAADLLQAKQQILTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEME 311
Query: 95 KDTDLVTKRILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAE 154
+D K++ ++ +I E + + EL K+ E K+ LK +K L
Sbjct: 312 QD-----KKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLLG------ 360
Query: 155 NEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARH 214
E+ + I + N EI +K L S++KER + + +K +L T LQK +
Sbjct: 361 -ELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIK----QLMGTVEELQKRNH----KD 411
Query: 215 LPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDE---- 270
D+ +++ +T+R++++L L+ Q+ E R + A E
Sbjct: 412 SQFETDIVQRME------QETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKT 465
Query: 271 -NKVLQKEVQRLYHKLKEKERELDIKNIYSNRL---------PKSSPNKEKELALRKNAA 320
+K + R Y + E ++ + N+ N L K +E L L + A
Sbjct: 466 RHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCA 525
Query: 321 CQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTL----DLQSQ----- 371
Q DL + F E+ +TI E+K E H +L DL+++
Sbjct: 526 LQRQLEDLVEE-----LSFSREQIQRARQTIAEQESKLNE-AHKSLSTVEDLKAEIVSAS 579
Query: 372 ----KQDRHGEAGILN-----PIMEREEKFVTDEELHVVKQEVEKLEDEW---EREELDK 419
+ + EA + N ++E+E+ V D + E+E+L + EEL K
Sbjct: 580 ESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSK 639
Query: 420 KQKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERL-----KREMLLAKLNEI 474
+++ LE E + E + LG++ Q +D LQ E +++ +++ L+ K N++
Sbjct: 640 LKED----LEIEHRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQL 695
Query: 475 DRELQDSRNLK 485
E+ ++L+
Sbjct: 696 ILEISKLKDLQ 706
Score = 53.9 bits (128), Expect = 5e-07
Identities = 92/394 (23%), Positives = 173/394 (43%), Gaps = 70/394 (17%)
Query: 141 YRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQ------EKERATEKRVKDT-- 192
Y EK L FE E + +I R E+ RL++ + ++ER R K+
Sbjct: 1927 YADEKTL--FERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMK 1984
Query: 193 ------ESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELS--K 244
E +L + L K K + + RDDL K++ + E+ +++ R EL K
Sbjct: 1985 AEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEK 2044
Query: 245 NLEL-----STNSFQRQLLAERK----RAYEAHDENKVLQKEVQRLYHKLKEKERELDIK 295
N EL + ++QL RK +A + E V Q+E+Q+L +LK R I
Sbjct: 2045 NTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPIS 2104
Query: 296 NIYSNRLP------KSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYP---- 345
+ + K +K EL L K Q D + + ++ +E F+ E
Sbjct: 2105 EHQTREVEQLANHLKEKTDKCSELLLSKE-QLQRDIQER-NEEIEKLE-FRVRELEQALL 2161
Query: 346 LTPETIMCYENK-----WEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVT--DEEL 398
++ +T E++ E L+L++Q Q + ++R+EK +T +E+L
Sbjct: 2162 VSADTFQKVEDRKHFGAVEAKPELSLEVQLQAE---------RDAIDRKEKEITNLEEQL 2212
Query: 399 HVVKQEVEKLEDEWER--EELDKKQKEKASLLE--REEKPEWETGRYQLGMYPIQNMDKL 454
++E+E +E ++ +L+ ++KE + L+ +E ++ +LG+ I+ D +
Sbjct: 2213 EQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGL-AIKESDAM 2271
Query: 455 QGEEEERL---------KREMLLAKLNEIDRELQ 479
+++ L ++E+ + +LNE +LQ
Sbjct: 2272 STQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQ 2305
Score = 48.5 bits (114), Expect = 2e-05
Identities = 86/403 (21%), Positives = 164/403 (40%), Gaps = 75/403 (18%)
Query: 119 VSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKS 178
+SE+Q A++ +LKR Q ++ + E + + E++++K+R +
Sbjct: 3091 LSEIQALHAQMNGRKITLKREQESEKPSQELLEYNIQQKQSQMLEMQVELSSMKDRATEL 3150
Query: 179 QEKERATEKRVKDTESELFRTKFSLQ--------KLKEISEARHLPERD----------- 219
QE+ + + V + +SEL +TK L+ LKE+ EA L +D
Sbjct: 3151 QEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHLKEL-EAFRLEVKDKTDEVHLLNDT 3209
Query: 220 ---------DLAKKLVSAELKLDDTERRIKELSKNLELSTNS-----FQRQLLAERKRAY 265
+L L + KL +E R KE ++L+ S S Q LL E+++
Sbjct: 3210 LASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQKQL 3269
Query: 266 EAHDENKVLQKEVQRLYHKL---KEKERELDIKNIYSN-----RLPKSSPNKEKELALRK 317
+ K+ E QR+ + +E+ R L+++ + + R S+ ++E+EL
Sbjct: 3270 LNESQQKI---ESQRMLYDAQLSEEQGRNLELQVLLESEKVRIREMSSTLDREREL---- 3322
Query: 318 NAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHG 377
+A QS ++ ED E E E LD +Q
Sbjct: 3323 HAQLQSSDGTGQSRPPLPSEDLLKELQKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEK 3382
Query: 378 EAGILNPIMEREEKFVTD--EELHVVKQEVEKLEDEWERE-----ELDKKQKEKASLLER 430
+ + ++ E++ T+ +++H ++ +VE L+ + E + +LD + + +++
Sbjct: 3383 DRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQLEEKRQQVYKLDLEGQRLQGIMQE 3442
Query: 431 EEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNE 473
+K E E EE+R R +L LNE
Sbjct: 3443 FQKQELE-------------------REEKRESRRILYQNLNE 3466
Score = 47.4 bits (111), Expect = 5e-05
Identities = 65/326 (19%), Positives = 130/326 (39%), Gaps = 29/326 (8%)
Query: 110 LKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEIT 169
L+INELQ E+ L+ + E + ++ LQ + E + ++ EN++ + + E +
Sbjct: 719 LQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENS 778
Query: 170 ALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEAR---HLPERDDLAKKLV 226
LK+ +K+ E V E +F + + E + E +DL ++ +
Sbjct: 779 ILKDE-KKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCI 837
Query: 227 SAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLK 286
+++ KN E++ Q + K + D + E + KLK
Sbjct: 838 QLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQELEYK---SKLK 894
Query: 287 EKERELDIKNIYSNRLP-KSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYP 345
EL ++ I + KSS E + + + T+ ++ +E K E+
Sbjct: 895 ALNEELHLQRINPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREKLE 954
Query: 346 LTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIME--REEKFVTDEELHVVKQ 403
L+ DL Q + +HGE LN ++ ++EK E++ + +
Sbjct: 955 LSQR---------------LSDLSEQLKQKHGEISFLNEEVKSLKQEK----EQVSLRCR 995
Query: 404 EVEKLEDEWEREELDKKQKEKASLLE 429
E+E + + E + + +SLL+
Sbjct: 996 ELEIIINHNRAENVQSCDTQVSSLLD 1021
Score = 45.4 bits (106), Expect = 2e-04
Identities = 121/592 (20%), Positives = 244/592 (41%), Gaps = 106/592 (17%)
Query: 86 QSLNREPLRKDTDLVTKRILSARLLKINELQNEVSEL------QVKLAELLKENKSLKRL 139
Q N + + +TD+V +R+ K+ +L+ E+ E+ Q+K + + ++ +
Sbjct: 405 QKRNHKDSQFETDIV-QRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEM 463
Query: 140 QYRQ----EKALNKFED-------------AENEISQLIFRHNNEITALKERLRKSQEKE 182
+ R E AL + + A NE++ + N++ LKE L E++
Sbjct: 464 KTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEK 523
Query: 183 RATEKRVKDTESELFRTKFSLQKLKE--------ISEA-RHLPERDDLAKKLVSAELKLD 233
A +++++D EL ++ +Q+ ++ ++EA + L +DL ++VSA
Sbjct: 524 CALQRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSAS---- 579
Query: 234 DTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELD 293
R+ EL E++ + ++L + K N VL + + +L+ +L
Sbjct: 580 -ESRKELELKHEAEVTNYKIKLEMLEKEK--------NAVLDRMAESQEAELERLRTQL- 629
Query: 294 IKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTK----GVQTMEDFKPEEYPLTPE 349
++S+ S ++ E+ R N D + K G+Q K E +
Sbjct: 630 ---LFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKD 686
Query: 350 TIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILN--------PIMEREEKFVTDEELHVV 401
++ +N+ DLQ + E L I+ +EEK E +
Sbjct: 687 NLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEK-----EKGTL 741
Query: 402 KQEVEKLEDEWEREELDKKQKEKAS-LLEREEKPEWETGRYQLGMYPIQNMDKLQ---GE 457
+QEV++L+ + E L+K+ KEK + L E+ + E E + +++M K+ +
Sbjct: 742 EQEVQELQ--LKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIHTPVSQ 799
Query: 458 EEERLKREMLLAKL------NEIDRELQDSRNLKYPVLPLLPDFESKLHSPERSPKTYRF 511
EE + + + +K EI+ ++++ +LK + L + E+ T+ F
Sbjct: 800 EERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEI-------EKQRNTFSF 852
Query: 512 SESSERLFNGHHLQ-----------DISFSTPKGEGQNSGNVRSPASPNEFAFGSYVPSF 560
+E + + N LQ D+ S K E + ++ A E P+
Sbjct: 853 AEKNFEV-NYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLK--ALNEELHLQRINPTT 909
Query: 561 AKTSERSNPFSQKSSFLDFQRNSMEKLSKDGVDLITR----KEKKANLMEQL 608
K +S+ F + +F+ E + KD +L+ + K +K L ++L
Sbjct: 910 VKM--KSSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRL 959
Score = 42.7 bits (99), Expect = 0.001
Identities = 71/358 (19%), Positives = 149/358 (41%), Gaps = 72/358 (20%)
Query: 116 QNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERL 175
++E Q ++ +L ++ K + R Q E + E N + + + + + + ++
Sbjct: 2077 EHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQ 2136
Query: 176 RKSQEKERATEK---RVKDTESELFRTKFSLQKLK------------EIS-EARHLPERD 219
R QE+ EK RV++ E L + + QK++ E+S E + ERD
Sbjct: 2137 RDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEAKPELSLEVQLQAERD 2196
Query: 220 DLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQR---QLLAERK----RAYEAHDENK 272
+ +K E ++ + E ++++ + LE Q+ QL ++K R E ENK
Sbjct: 2197 AIDRK----EKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENK 2252
Query: 273 VLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKG 332
+ + ++++L +KE + + +++ + K FA + +
Sbjct: 2253 LFKDDMEKLGLAIKESD---------------AMSTQDQHVLFGK-------FAQIIQEK 2290
Query: 333 VQTMEDFKPEEYPLTPETIMCYENK-WEEPGHLTLDLQSQ-----------KQDRHGEAG 380
++ + L + + +NK EE L DL++Q K++R E
Sbjct: 2291 EVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIE 2350
Query: 381 ILNPIMEREEKFV------TDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLEREE 432
LN ++E+ ++ + T H + +E + L + +LD EK +L ++ E
Sbjct: 2351 QLNEVIEKLQQELANIGQKTSMNAHSLSEEADSL-----KHQLDVVIAEKLALEQQVE 2403
Score = 40.0 bits (92), Expect = 0.007
Identities = 84/393 (21%), Positives = 162/393 (41%), Gaps = 37/393 (9%)
Query: 78 GVRVGFRSQSLNREP--LRKDTDLVT--KRILSARLLKINE----LQNEVSELQVKLAEL 129
G + + SL+ E L+ D+V K L ++ NE ++N + E K+ +L
Sbjct: 2367 GQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLKETNFKMNQL 2426
Query: 130 LKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEI-TALKERLRKSQEKERATEKR 188
+E SLKR + EK + E++ N + + E+ L E KS E + +
Sbjct: 2427 TQELFSLKRERESVEKIQSIPENSVNVAIDHLSKDKPELEVVLTEDALKSLENQTYFKSF 2486
Query: 189 VKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVS----AELKLDDTERRIKELSK 244
++ + + + L +L+ A+ L E K++ + + + +++I L K
Sbjct: 2487 EENGKGSIINLETRLLQLESTVSAKDL-ELTQCYKQIKDMQEQGQFETEMLQKKIVNLQK 2545
Query: 245 NLELSTNSF---QRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSNR 301
+E + Q QL A ++ A D N+ + E +R + + RE ++ + S
Sbjct: 2546 IVEEKVAAALVSQIQLEAVQEYAKFCQD-NQTISSEPERTNIQNLNQLREDELGSDISAL 2604
Query: 302 LPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTP--ETIMCYENKWE 359
+ S + + + + + + + ++ K V E E L E + K
Sbjct: 2605 TLRISELESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLELQKLLEGNEKKQREKEKKR 2664
Query: 360 EPGHL-TLDLQSQKQDRHGEAGILNPIME-REEKFVTDEELHVVKQEVEKLEDEWEREEL 417
P + L ++ + E+G N + R E T EL K++ EKL++E +E
Sbjct: 2665 SPQDVEVLKTTTELFHSNEESGFFNELEALRAESVATKAELASYKEKAEKLQEELLVKET 2724
Query: 418 DK---------------KQKEKASLLEREEKPE 435
+ + KEK S+LE+E++ E
Sbjct: 2725 NMTSLQKDLSQVRDHLAEAKEKLSILEKEDETE 2757
Score = 37.0 bits (84), Expect = 0.062
Identities = 75/370 (20%), Positives = 160/370 (43%), Gaps = 62/370 (16%)
Query: 111 KINELQNE-VSELQVKLAELLKENKSLKRLQYRQEKALNK-FEDAENEISQL-------- 160
K+ E +NE + +L+ ++ L+ + + +KR + + + LN+ E + E++ +
Sbjct: 2315 KVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQELANIGQKTSMNA 2374
Query: 161 --------IFRHNNEITALKERLRKSQEKERATEKR------VKDTE---SELFRTKFSL 203
+H ++ + E+L Q+ E A E+ +K+T ++L + FSL
Sbjct: 2375 HSLSEEADSLKHQLDVV-IAEKLALEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSL 2433
Query: 204 QKLKE-ISEARHLPER------DDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQ 256
++ +E + + + +PE D L+K E+ L + + E + + +
Sbjct: 2434 KRERESVEKIQSIPENSVNVAIDHLSKDKPELEVVLTEDALKSLENQTYFKSFEENGKGS 2493
Query: 257 LLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALR 316
++ R + E+ + Y ++K+ + + + + L K N +K + +
Sbjct: 2494 IINLETRLLQLESTVSAKDLELTQCYKQIKDMQEQGQFE---TEMLQKKIVNLQKIVEEK 2550
Query: 317 KNAACQS--------DFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTL-- 366
AA S ++A C QT+ +PE + + + + LTL
Sbjct: 2551 VAAALVSQIQLEAVQEYAKFCQDN-QTISS-EPERTNIQNLNQLREDELGSDISALTLRI 2608
Query: 367 -DLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQKEKA 425
+L+SQ + H I+E+E+ V E +V+++E + LE + E +KKQ+EK
Sbjct: 2609 SELESQVVEMHTSL-----ILEKEQ--VEIAEKNVLEKEKKLLELQKLLEGNEKKQREK- 2660
Query: 426 SLLEREEKPE 435
E++ P+
Sbjct: 2661 ---EKKRSPQ 2667
Score = 36.2 bits (82), Expect = 0.11
Identities = 83/412 (20%), Positives = 169/412 (41%), Gaps = 59/412 (14%)
Query: 109 LLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKA-------------LNKFEDAE- 154
L K+ E N++ LQ +L+++ + +L++ +E + ED +
Sbjct: 1260 LNKVTEEYNKLLVLQTRLSKIWGQQTDGMKLEFGEENLPKEETEFLSIHSQMTNLEDIDV 1319
Query: 155 NEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQK-LKEISEAR 213
N S+L + E T L+E++++ + + ++++K+TE LQK L+ +SE+
Sbjct: 1320 NHKSKLSSLQDLEKTKLEEQVQELESLISSLQQQLKETEQNYEAEIHCLQKRLQAVSEST 1379
Query: 214 HLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKV 273
P +V E T + KN++ T F + + E + K+
Sbjct: 1380 VPPSLP--VDSVVITESDAQRTMYPGSCVKKNID-GTIEFSGEFGVK-----EETNIVKL 1431
Query: 274 LQKEVQ-RLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRK-NAACQSD---FADL 328
L+K+ Q +L ++ + + I L + S KE + ++ +A CQ + F ++
Sbjct: 1432 LEKQYQEQLEEEVAKVIVSMSIAFAQQTELSRISGGKENTASSKQAHAVCQQEQHYFNEM 1491
Query: 329 CTK----GVQTME----DFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAG 380
G QT E FK E PL+ +E G ++ D H
Sbjct: 1492 KLSQDQIGFQTFETVDVKFKEEFKPLS-----------KELGEHGKEILLSNSDPHDIPE 1540
Query: 381 ILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLEREEKPEWETGR 440
+ ++ E+ + ++ +V+Q + DE +D ++ + + E+ + +
Sbjct: 1541 SKDCVLTISEEMFSKDKTFIVRQSI---HDEISVSSMDASRQLMLNEEQLEDMRQELVRQ 1597
Query: 441 YQ--------LGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQDSRNL 484
YQ L ++ M++ Q E++E+L+ E+ R D+ NL
Sbjct: 1598 YQEHQQATELLRQAHMRQMER-QREDQEQLQEEIKRLNRQLAQRSSIDNENL 1648
Score = 32.7 bits (73), Expect = 1.2
Identities = 36/174 (20%), Positives = 75/174 (43%), Gaps = 12/174 (6%)
Query: 45 SVRRKNPKRQTSDGQVHHQAPRKPSPKGLPNRKGVRVGFRSQSLNRE-----PLRKDTDL 99
S ++ +R D Q+ + R + L + VR+ S +L+RE L+
Sbjct: 3273 SQQKIESQRMLYDAQLSEEQGRNLELQVLLESEKVRIREMSSTLDRERELHAQLQSSDGT 3332
Query: 100 VTKR--ILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEI 157
R + S LLK ELQ ++ E ++ ELL E + K + + + K +
Sbjct: 3333 GQSRPPLPSEDLLK--ELQKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKT 3390
Query: 158 SQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISE 211
Q N E ++++ + Q K ++++++ ++++ Q+L+ I +
Sbjct: 3391 LQTEQEANTE---GQKKMHELQSKVEDLQRQLEEKRQQVYKLDLEGQRLQGIMQ 3441
Score = 32.0 bits (71), Expect = 2.0
Identities = 82/435 (18%), Positives = 182/435 (41%), Gaps = 67/435 (15%)
Query: 114 ELQNEVSELQVKLAELLKENKSLKRLQYRQE-KALNK------------------FEDAE 154
ELQ E + L +K+ + L+++K+ + L+Y+ + KALN+ F++ +
Sbjct: 863 ELQEEYACL-LKVKDDLEDSKNKQELEYKSKLKALNEELHLQRINPTTVKMKSSVFDEDK 921
Query: 155 NEISQLIFRHN---NEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISE 211
+++ + + T L E+L ++ ++ +R+ D +L + + L E E
Sbjct: 922 TFVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLSDLSEQLKQKHGEISFLNE--E 979
Query: 212 ARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAH--- 268
+ L + + L EL++ R + + ++ + +S ++ R E
Sbjct: 980 VKSLKQEKEQVS-LRCRELEIIINHNRAENV-QSCDTQVSSLLDGVVTMTSRGAEGSVSK 1037
Query: 269 ------DENKVLQKE---VQRLYHKLKEKERELDIKNIYS--------NRLPKSSPNKEK 311
+E+K++ ++ + + + K+ +L + ++ S P + +K
Sbjct: 1038 VNKSFGEESKIMVEDKVSFENMTVGEESKQEQLILDHLPSVTKESSLRATQPSENDKLQK 1097
Query: 312 ELALRKNAA----CQSDFADLCTKGVQTMEDFKPEEY----------PLTPETIMCYENK 357
EL + K+ Q + +C V + + EY L E I E K
Sbjct: 1098 ELNVLKSEQNDLRLQMEAQRICLSLVYSTHVDQVREYMENEKDKALCSLKEELIFAQEEK 1157
Query: 358 WEEPGHL-TLDLQSQKQDRHGEAGI-LNPIMEREEKFVTDEELHVVKQEVEKLEDEWE-- 413
+E + L+LQ+ K G+ G L+ ++ + +K V++E + ++ L + +
Sbjct: 1158 IKELQKIHQLELQTMKTQETGDEGKPLHLLIGKLQKAVSEECSYFLQTLCSVLGEYYTPA 1217
Query: 414 -REELDKKQKEKAS-LLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKL 471
+ E++ + KE + + E PE + RY++ + L EE K +L +L
Sbjct: 1218 LKCEVNAEDKENSGDYISENEDPELQDYRYEVQDFQENMHTLLNKVTEEYNKLLVLQTRL 1277
Query: 472 NEIDRELQDSRNLKY 486
++I + D L++
Sbjct: 1278 SKIWGQQTDGMKLEF 1292
Score = 31.6 bits (70), Expect = 2.6
Identities = 50/228 (21%), Positives = 95/228 (41%), Gaps = 45/228 (19%)
Query: 105 LSARLLKINELQNEVSEL---------QVKLAE--LLKENKSLKRLQYRQEKALNKFEDA 153
+SA L+I+EL+++V E+ QV++AE +L++ K L LQ E K +
Sbjct: 2601 ISALTLRISELESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLELQKLLEGNEKKQREK 2660
Query: 154 ENEISQL----------IFRHN------NEITAL--------------KERLRKSQEKER 183
E + S +F N NE+ AL KE+ K QE+
Sbjct: 2661 EKKRSPQDVEVLKTTTELFHSNEESGFFNELEALRAESVATKAELASYKEKAEKLQEELL 2720
Query: 184 ATEKRVKDTESELFRTKFSLQKLKE---ISEARHLPERDDLAKKLVSAELKLDDTERRIK 240
E + + +L + + L + KE I E E + K + L + ++
Sbjct: 2721 VKETNMTSLQKDLSQVRDHLAEAKEKLSILEKEDETEVQESKKACMFEPLPIKLSKSIAS 2780
Query: 241 ELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEK 288
+ L++S+++ Q+L + + + +++ +EV + + EK
Sbjct: 2781 QTDGTLKISSSNQTPQILV-KNAGIQINLQSECSSEEVTEIISQFTEK 2827
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 66.6 bits (161), Expect = 7e-11
Identities = 105/491 (21%), Positives = 202/491 (41%), Gaps = 76/491 (15%)
Query: 35 RSSLVSSSPASVRRKNPKRQTSDGQVHHQAPRKPSPKGLPNRKGVRVGFRSQSLNREPLR 94
R+S SS+ A + + + T Q+ Q + +++ F + + +
Sbjct: 252 RNSTHSSTAADLLQAKQQILTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEME 311
Query: 95 KDTDLVTKRILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAE 154
+D K++ ++ +I E + + EL K+ E K+ LK +K L
Sbjct: 312 QD-----KKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLLG------ 360
Query: 155 NEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARH 214
E+ + I + N EI +K L S++KER + + +K +L T LQK +
Sbjct: 361 -ELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIK----QLMGTVEELQKRNH----KD 411
Query: 215 LPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDE---- 270
D+ +++ +T+R++++L L+ Q+ E R + A E
Sbjct: 412 SQFETDIVQRME------QETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKT 465
Query: 271 -NKVLQKEVQRLYHKLKEKERELDIKNIYSNRL---------PKSSPNKEKELALRKNAA 320
+K + R Y + E ++ + N+ N L K +E L L + A
Sbjct: 466 RHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCA 525
Query: 321 CQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTL----DLQSQ----- 371
Q DL + F E+ +TI E+K E H +L DL+++
Sbjct: 526 LQRQLEDLVEE-----LSFSREQIQRARQTIAEQESKLNE-AHKSLSTVEDLKAEIVSAS 579
Query: 372 ----KQDRHGEAGILN-----PIMEREEKFVTDEELHVVKQEVEKLEDEW---EREELDK 419
+ + EA + N ++E+E+ V D + E+E+L + EEL K
Sbjct: 580 ESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSK 639
Query: 420 KQKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERL-----KREMLLAKLNEI 474
+++ LE E + E + LG++ Q +D LQ E +++ +++ L+ K N++
Sbjct: 640 LKED----LEIEHRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQL 695
Query: 475 DRELQDSRNLK 485
E+ ++L+
Sbjct: 696 ILEISKLKDLQ 706
Score = 54.3 bits (129), Expect = 4e-07
Identities = 91/389 (23%), Positives = 171/389 (43%), Gaps = 68/389 (17%)
Query: 141 YRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQ------EKERATEKRVKDT-- 192
Y EK L FE E + +I R E+ RL++ + ++ER R K+
Sbjct: 1927 YADEKTL--FERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMK 1984
Query: 193 ------ESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELS--K 244
E +L + L K K + + RDDL K++ + E+ +++ R EL K
Sbjct: 1985 AEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEK 2044
Query: 245 NLEL-----STNSFQRQLLAERK----RAYEAHDENKVLQKEVQRLYHKLKEKERELDIK 295
N EL + ++QL RK +A + E V Q+E+Q+L +LK R I
Sbjct: 2045 NTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPIS 2104
Query: 296 NIYSNRLP------KSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPE 349
+ + K +K EL L K Q D + + ++ +E F+ E +
Sbjct: 2105 EHQTREVEQLANHLKEKTDKCSELLLSKE-QLQRDIQER-NEEIEKLE-FRVRE---LEQ 2158
Query: 350 TIMCYENKW----EEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVT--DEELHVVKQ 403
++ + K E L+L++Q Q + ++R+EK +T +E+L ++
Sbjct: 2159 ALLVEDRKHFGAVEAKPELSLEVQLQAE---------RDAIDRKEKEITNLEEQLEQFRE 2209
Query: 404 EVEKLEDEWER--EELDKKQKEKASLLE--REEKPEWETGRYQLGMYPIQNMDKLQGEEE 459
E+E +E ++ +L+ ++KE + L+ +E ++ +LG+ I+ D + +++
Sbjct: 2210 ELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGL-AIKESDAMSTQDQ 2268
Query: 460 ERL---------KREMLLAKLNEIDRELQ 479
L ++E+ + +LNE +LQ
Sbjct: 2269 HVLFGKFAQIIQEKEVEIDQLNEQVTKLQ 2297
Score = 48.5 bits (114), Expect = 2e-05
Identities = 86/403 (21%), Positives = 164/403 (40%), Gaps = 75/403 (18%)
Query: 119 VSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKS 178
+SE+Q A++ +LKR Q ++ + E + + E++++K+R +
Sbjct: 3083 LSEIQALHAQMNGRKITLKREQESEKPSQELLEYNIQQKQSQMLEMQVELSSMKDRATEL 3142
Query: 179 QEKERATEKRVKDTESELFRTKFSLQ--------KLKEISEARHLPERD----------- 219
QE+ + + V + +SEL +TK L+ LKE+ EA L +D
Sbjct: 3143 QEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHLKEL-EAFRLEVKDKTDEVHLLNDT 3201
Query: 220 ---------DLAKKLVSAELKLDDTERRIKELSKNLELSTNS-----FQRQLLAERKRAY 265
+L L + KL +E R KE ++L+ S S Q LL E+++
Sbjct: 3202 LASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQKQL 3261
Query: 266 EAHDENKVLQKEVQRLYHKL---KEKERELDIKNIYSN-----RLPKSSPNKEKELALRK 317
+ K+ E QR+ + +E+ R L+++ + + R S+ ++E+EL
Sbjct: 3262 LNESQQKI---ESQRMLYDAQLSEEQGRNLELQVLLESEKVRIREMSSTLDREREL---- 3314
Query: 318 NAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHG 377
+A QS ++ ED E E E LD +Q
Sbjct: 3315 HAQLQSSDGTGQSRPPLPSEDLLKELQKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEK 3374
Query: 378 EAGILNPIMEREEKFVTD--EELHVVKQEVEKLEDEWERE-----ELDKKQKEKASLLER 430
+ + ++ E++ T+ +++H ++ +VE L+ + E + +LD + + +++
Sbjct: 3375 DRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQLEEKRQQVYKLDLEGQRLQGIMQE 3434
Query: 431 EEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNE 473
+K E E EE+R R +L LNE
Sbjct: 3435 FQKQELE-------------------REEKRESRRILYQNLNE 3458
Score = 47.4 bits (111), Expect = 5e-05
Identities = 65/326 (19%), Positives = 130/326 (39%), Gaps = 29/326 (8%)
Query: 110 LKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEIT 169
L+INELQ E+ L+ + E + ++ LQ + E + ++ EN++ + + E +
Sbjct: 719 LQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENS 778
Query: 170 ALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEAR---HLPERDDLAKKLV 226
LK+ +K+ E V E +F + + E + E +DL ++ +
Sbjct: 779 ILKDE-KKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCI 837
Query: 227 SAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLK 286
+++ KN E++ Q + K + D + E + KLK
Sbjct: 838 QLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQELEYK---SKLK 894
Query: 287 EKERELDIKNIYSNRLP-KSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYP 345
EL ++ I + KSS E + + + T+ ++ +E K E+
Sbjct: 895 ALNEELHLQRINPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREKLE 954
Query: 346 LTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIME--REEKFVTDEELHVVKQ 403
L+ DL Q + +HGE LN ++ ++EK E++ + +
Sbjct: 955 LSQR---------------LSDLSEQLKQKHGEISFLNEEVKSLKQEK----EQVSLRCR 995
Query: 404 EVEKLEDEWEREELDKKQKEKASLLE 429
E+E + + E + + +SLL+
Sbjct: 996 ELEIIINHNRAENVQSCDTQVSSLLD 1021
Score = 45.4 bits (106), Expect = 2e-04
Identities = 121/592 (20%), Positives = 244/592 (41%), Gaps = 106/592 (17%)
Query: 86 QSLNREPLRKDTDLVTKRILSARLLKINELQNEVSEL------QVKLAELLKENKSLKRL 139
Q N + + +TD+V +R+ K+ +L+ E+ E+ Q+K + + ++ +
Sbjct: 405 QKRNHKDSQFETDIV-QRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEM 463
Query: 140 QYRQ----EKALNKFED-------------AENEISQLIFRHNNEITALKERLRKSQEKE 182
+ R E AL + + A NE++ + N++ LKE L E++
Sbjct: 464 KTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEK 523
Query: 183 RATEKRVKDTESELFRTKFSLQKLKE--------ISEA-RHLPERDDLAKKLVSAELKLD 233
A +++++D EL ++ +Q+ ++ ++EA + L +DL ++VSA
Sbjct: 524 CALQRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSAS---- 579
Query: 234 DTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELD 293
R+ EL E++ + ++L + K N VL + + +L+ +L
Sbjct: 580 -ESRKELELKHEAEVTNYKIKLEMLEKEK--------NAVLDRMAESQEAELERLRTQL- 629
Query: 294 IKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTK----GVQTMEDFKPEEYPLTPE 349
++S+ S ++ E+ R N D + K G+Q K E +
Sbjct: 630 ---LFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKD 686
Query: 350 TIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILN--------PIMEREEKFVTDEELHVV 401
++ +N+ DLQ + E L I+ +EEK E +
Sbjct: 687 NLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEK-----EKGTL 741
Query: 402 KQEVEKLEDEWEREELDKKQKEKAS-LLEREEKPEWETGRYQLGMYPIQNMDKLQ---GE 457
+QEV++L+ + E L+K+ KEK + L E+ + E E + +++M K+ +
Sbjct: 742 EQEVQELQ--LKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIHTPVSQ 799
Query: 458 EEERLKREMLLAKL------NEIDRELQDSRNLKYPVLPLLPDFESKLHSPERSPKTYRF 511
EE + + + +K EI+ ++++ +LK + L + E+ T+ F
Sbjct: 800 EERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEI-------EKQRNTFSF 852
Query: 512 SESSERLFNGHHLQ-----------DISFSTPKGEGQNSGNVRSPASPNEFAFGSYVPSF 560
+E + + N LQ D+ S K E + ++ A E P+
Sbjct: 853 AEKNFEV-NYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLK--ALNEELHLQRINPTT 909
Query: 561 AKTSERSNPFSQKSSFLDFQRNSMEKLSKDGVDLITR----KEKKANLMEQL 608
K +S+ F + +F+ E + KD +L+ + K +K L ++L
Sbjct: 910 VKM--KSSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRL 959
Score = 43.1 bits (100), Expect = 9e-04
Identities = 72/350 (20%), Positives = 147/350 (42%), Gaps = 64/350 (18%)
Query: 116 QNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERL 175
++E Q ++ +L ++ K + R Q E + E N + + + + + + ++
Sbjct: 2077 EHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQ 2136
Query: 176 RKSQEKERATEK---RVKDTESELF---RTKFSLQKLK-EIS-EARHLPERDDLAKKLVS 227
R QE+ EK RV++ E L R F + K E+S E + ERD + +K
Sbjct: 2137 RDIQERNEEIEKLEFRVRELEQALLVEDRKHFGAVEAKPELSLEVQLQAERDAIDRK--- 2193
Query: 228 AELKLDDTERRIKELSKNLELSTNSFQR---QLLAERK----RAYEAHDENKVLQKEVQR 280
E ++ + E ++++ + LE Q+ QL ++K R E ENK+ + ++++
Sbjct: 2194 -EKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEK 2252
Query: 281 LYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFK 340
L +KE + + +++ + K FA + + ++
Sbjct: 2253 LGLAIKESD---------------AMSTQDQHVLFGK-------FAQIIQEKEVEIDQLN 2290
Query: 341 PEEYPLTPETIMCYENK-WEEPGHLTLDLQSQ-----------KQDRHGEAGILNPIMER 388
+ L + + +NK EE L DL++Q K++R E LN ++E+
Sbjct: 2291 EQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEK 2350
Query: 389 EEKFV------TDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLEREE 432
++ + T H + +E + L + +LD EK +L ++ E
Sbjct: 2351 LQQELANIGQKTSMNAHSLSEEADSL-----KHQLDVVIAEKLALEQQVE 2395
Score = 40.0 bits (92), Expect = 0.007
Identities = 84/393 (21%), Positives = 162/393 (41%), Gaps = 37/393 (9%)
Query: 78 GVRVGFRSQSLNREP--LRKDTDLVT--KRILSARLLKINE----LQNEVSELQVKLAEL 129
G + + SL+ E L+ D+V K L ++ NE ++N + E K+ +L
Sbjct: 2359 GQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLKETNFKMNQL 2418
Query: 130 LKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEI-TALKERLRKSQEKERATEKR 188
+E SLKR + EK + E++ N + + E+ L E KS E + +
Sbjct: 2419 TQELFSLKRERESVEKIQSIPENSVNVAIDHLSKDKPELEVVLTEDALKSLENQTYFKSF 2478
Query: 189 VKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVS----AELKLDDTERRIKELSK 244
++ + + + L +L+ A+ L E K++ + + + +++I L K
Sbjct: 2479 EENGKGSIINLETRLLQLESTVSAKDL-ELTQCYKQIKDMQEQGQFETEMLQKKIVNLQK 2537
Query: 245 NLELSTNSF---QRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSNR 301
+E + Q QL A ++ A D N+ + E +R + + RE ++ + S
Sbjct: 2538 IVEEKVAAALVSQIQLEAVQEYAKFCQD-NQTISSEPERTNIQNLNQLREDELGSDISAL 2596
Query: 302 LPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTP--ETIMCYENKWE 359
+ S + + + + + + + ++ K V E E L E + K
Sbjct: 2597 TLRISELESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLELQKLLEGNEKKQREKEKKR 2656
Query: 360 EPGHL-TLDLQSQKQDRHGEAGILNPIME-REEKFVTDEELHVVKQEVEKLEDEWEREEL 417
P + L ++ + E+G N + R E T EL K++ EKL++E +E
Sbjct: 2657 SPQDVEVLKTTTELFHSNEESGFFNELEALRAESVATKAELASYKEKAEKLQEELLVKET 2716
Query: 418 DK---------------KQKEKASLLEREEKPE 435
+ + KEK S+LE+E++ E
Sbjct: 2717 NMTSLQKDLSQVRDHLAEAKEKLSILEKEDETE 2749
Score = 37.0 bits (84), Expect = 0.062
Identities = 75/370 (20%), Positives = 160/370 (43%), Gaps = 62/370 (16%)
Query: 111 KINELQNE-VSELQVKLAELLKENKSLKRLQYRQEKALNK-FEDAENEISQL-------- 160
K+ E +NE + +L+ ++ L+ + + +KR + + + LN+ E + E++ +
Sbjct: 2307 KVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQELANIGQKTSMNA 2366
Query: 161 --------IFRHNNEITALKERLRKSQEKERATEKR------VKDTE---SELFRTKFSL 203
+H ++ + E+L Q+ E A E+ +K+T ++L + FSL
Sbjct: 2367 HSLSEEADSLKHQLDVV-IAEKLALEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSL 2425
Query: 204 QKLKE-ISEARHLPER------DDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQ 256
++ +E + + + +PE D L+K E+ L + + E + + +
Sbjct: 2426 KRERESVEKIQSIPENSVNVAIDHLSKDKPELEVVLTEDALKSLENQTYFKSFEENGKGS 2485
Query: 257 LLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALR 316
++ R + E+ + Y ++K+ + + + + L K N +K + +
Sbjct: 2486 IINLETRLLQLESTVSAKDLELTQCYKQIKDMQEQGQFE---TEMLQKKIVNLQKIVEEK 2542
Query: 317 KNAACQS--------DFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTL-- 366
AA S ++A C QT+ +PE + + + + LTL
Sbjct: 2543 VAAALVSQIQLEAVQEYAKFCQDN-QTISS-EPERTNIQNLNQLREDELGSDISALTLRI 2600
Query: 367 -DLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQKEKA 425
+L+SQ + H I+E+E+ V E +V+++E + LE + E +KKQ+EK
Sbjct: 2601 SELESQVVEMHTSL-----ILEKEQ--VEIAEKNVLEKEKKLLELQKLLEGNEKKQREK- 2652
Query: 426 SLLEREEKPE 435
E++ P+
Sbjct: 2653 ---EKKRSPQ 2659
Score = 36.2 bits (82), Expect = 0.11
Identities = 83/412 (20%), Positives = 169/412 (41%), Gaps = 59/412 (14%)
Query: 109 LLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKA-------------LNKFEDAE- 154
L K+ E N++ LQ +L+++ + +L++ +E + ED +
Sbjct: 1260 LNKVTEEYNKLLVLQTRLSKIWGQQTDGMKLEFGEENLPKEETEFLSIHSQMTNLEDIDV 1319
Query: 155 NEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQK-LKEISEAR 213
N S+L + E T L+E++++ + + ++++K+TE LQK L+ +SE+
Sbjct: 1320 NHKSKLSSLQDLEKTKLEEQVQELESLISSLQQQLKETEQNYEAEIHCLQKRLQAVSEST 1379
Query: 214 HLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKV 273
P +V E T + KN++ T F + + E + K+
Sbjct: 1380 VPPSLP--VDSVVITESDAQRTMYPGSCVKKNID-GTIEFSGEFGVK-----EETNIVKL 1431
Query: 274 LQKEVQ-RLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRK-NAACQSD---FADL 328
L+K+ Q +L ++ + + I L + S KE + ++ +A CQ + F ++
Sbjct: 1432 LEKQYQEQLEEEVAKVIVSMSIAFAQQTELSRISGGKENTASSKQAHAVCQQEQHYFNEM 1491
Query: 329 CTK----GVQTME----DFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAG 380
G QT E FK E PL+ +E G ++ D H
Sbjct: 1492 KLSQDQIGFQTFETVDVKFKEEFKPLS-----------KELGEHGKEILLSNSDPHDIPE 1540
Query: 381 ILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLEREEKPEWETGR 440
+ ++ E+ + ++ +V+Q + DE +D ++ + + E+ + +
Sbjct: 1541 SKDCVLTISEEMFSKDKTFIVRQSI---HDEISVSSMDASRQLMLNEEQLEDMRQELVRQ 1597
Query: 441 YQ--------LGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQDSRNL 484
YQ L ++ M++ Q E++E+L+ E+ R D+ NL
Sbjct: 1598 YQEHQQATELLRQAHMRQMER-QREDQEQLQEEIKRLNRQLAQRSSIDNENL 1648
Score = 32.7 bits (73), Expect = 1.2
Identities = 36/174 (20%), Positives = 75/174 (43%), Gaps = 12/174 (6%)
Query: 45 SVRRKNPKRQTSDGQVHHQAPRKPSPKGLPNRKGVRVGFRSQSLNRE-----PLRKDTDL 99
S ++ +R D Q+ + R + L + VR+ S +L+RE L+
Sbjct: 3265 SQQKIESQRMLYDAQLSEEQGRNLELQVLLESEKVRIREMSSTLDRERELHAQLQSSDGT 3324
Query: 100 VTKR--ILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEI 157
R + S LLK ELQ ++ E ++ ELL E + K + + + K +
Sbjct: 3325 GQSRPPLPSEDLLK--ELQKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKT 3382
Query: 158 SQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISE 211
Q N E ++++ + Q K ++++++ ++++ Q+L+ I +
Sbjct: 3383 LQTEQEANTE---GQKKMHELQSKVEDLQRQLEEKRQQVYKLDLEGQRLQGIMQ 3433
Score = 32.0 bits (71), Expect = 2.0
Identities = 82/435 (18%), Positives = 182/435 (41%), Gaps = 67/435 (15%)
Query: 114 ELQNEVSELQVKLAELLKENKSLKRLQYRQE-KALNK------------------FEDAE 154
ELQ E + L +K+ + L+++K+ + L+Y+ + KALN+ F++ +
Sbjct: 863 ELQEEYACL-LKVKDDLEDSKNKQELEYKSKLKALNEELHLQRINPTTVKMKSSVFDEDK 921
Query: 155 NEISQLIFRHN---NEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISE 211
+++ + + T L E+L ++ ++ +R+ D +L + + L E E
Sbjct: 922 TFVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLSDLSEQLKQKHGEISFLNE--E 979
Query: 212 ARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAH--- 268
+ L + + L EL++ R + + ++ + +S ++ R E
Sbjct: 980 VKSLKQEKEQVS-LRCRELEIIINHNRAENV-QSCDTQVSSLLDGVVTMTSRGAEGSVSK 1037
Query: 269 ------DENKVLQKE---VQRLYHKLKEKERELDIKNIYS--------NRLPKSSPNKEK 311
+E+K++ ++ + + + K+ +L + ++ S P + +K
Sbjct: 1038 VNKSFGEESKIMVEDKVSFENMTVGEESKQEQLILDHLPSVTKESSLRATQPSENDKLQK 1097
Query: 312 ELALRKNAA----CQSDFADLCTKGVQTMEDFKPEEY----------PLTPETIMCYENK 357
EL + K+ Q + +C V + + EY L E I E K
Sbjct: 1098 ELNVLKSEQNDLRLQMEAQRICLSLVYSTHVDQVREYMENEKDKALCSLKEELIFAQEEK 1157
Query: 358 WEEPGHL-TLDLQSQKQDRHGEAGI-LNPIMEREEKFVTDEELHVVKQEVEKLEDEWE-- 413
+E + L+LQ+ K G+ G L+ ++ + +K V++E + ++ L + +
Sbjct: 1158 IKELQKIHQLELQTMKTQETGDEGKPLHLLIGKLQKAVSEECSYFLQTLCSVLGEYYTPA 1217
Query: 414 -REELDKKQKEKAS-LLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKL 471
+ E++ + KE + + E PE + RY++ + L EE K +L +L
Sbjct: 1218 LKCEVNAEDKENSGDYISENEDPELQDYRYEVQDFQENMHTLLNKVTEEYNKLLVLQTRL 1277
Query: 472 NEIDRELQDSRNLKY 486
++I + D L++
Sbjct: 1278 SKIWGQQTDGMKLEF 1292
Score = 31.6 bits (70), Expect = 2.6
Identities = 50/228 (21%), Positives = 95/228 (41%), Gaps = 45/228 (19%)
Query: 105 LSARLLKINELQNEVSEL---------QVKLAE--LLKENKSLKRLQYRQEKALNKFEDA 153
+SA L+I+EL+++V E+ QV++AE +L++ K L LQ E K +
Sbjct: 2593 ISALTLRISELESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLELQKLLEGNEKKQREK 2652
Query: 154 ENEISQL----------IFRHN------NEITAL--------------KERLRKSQEKER 183
E + S +F N NE+ AL KE+ K QE+
Sbjct: 2653 EKKRSPQDVEVLKTTTELFHSNEESGFFNELEALRAESVATKAELASYKEKAEKLQEELL 2712
Query: 184 ATEKRVKDTESELFRTKFSLQKLKE---ISEARHLPERDDLAKKLVSAELKLDDTERRIK 240
E + + +L + + L + KE I E E + K + L + ++
Sbjct: 2713 VKETNMTSLQKDLSQVRDHLAEAKEKLSILEKEDETEVQESKKACMFEPLPIKLSKSIAS 2772
Query: 241 ELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEK 288
+ L++S+++ Q+L + + + +++ +EV + + EK
Sbjct: 2773 QTDGTLKISSSNQTPQILV-KNAGIQINLQSECSSEEVTEIISQFTEK 2819
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 66.2 bits (160), Expect = 1e-10
Identities = 67/334 (20%), Positives = 146/334 (43%), Gaps = 36/334 (10%)
Query: 113 NELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALK 172
+ L E+ + KL ++EN+ RL +QE+ + + E+ E + I +I +
Sbjct: 256 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQE 315
Query: 173 ERLRKSQEKERATEKRVKDTES----------ELFRTKFSLQKLKEISEARHLPERDDLA 222
E++R+ +E E++++ E EL +K++E E R E+
Sbjct: 316 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 375
Query: 223 KKLVSAELKLDDTERRIKELSKNLELSTNSFQRQ---LLAERKRAYEAHDENKVLQKEVQ 279
+K E K+ E +I+E + + Q Q + + ++ +E +E + +++++
Sbjct: 376 EKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMR 435
Query: 280 RLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDF 339
R K++E+E+++ + + +E+++ ++ C+ + K + E
Sbjct: 436 RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQE-----AKMQEQEEKM 490
Query: 340 KPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELH 399
+ +E E I E K E Q +K E + E+EEK EE
Sbjct: 491 RRQE-----EKIREQEKKIRE--------QEEKIREQEEM-----MQEQEEKMWEQEEKM 532
Query: 400 VVKQEVEKLEDEWEREELDKKQKEKASLLEREEK 433
++E + ++E R + +K ++++ L ++EEK
Sbjct: 533 CEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEK 566
Score = 55.5 bits (132), Expect = 2e-07
Identities = 82/383 (21%), Positives = 174/383 (45%), Gaps = 52/383 (13%)
Query: 112 INELQNEVSELQVKLAELLKE----NKSLKRLQYRQEKALNKFEDAENE---ISQLIFRH 164
+ +L+ E +L +L + K ++L + +++KA E+ E +S ++R+
Sbjct: 141 VKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRN 200
Query: 165 NNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLP-ERDDLAK 223
LKE+ K QEK + E + + + K L++ K + + L E D L K
Sbjct: 201 TITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGK 260
Query: 224 KLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYH 283
+L S KL ++ +N EL Q+Q ++ + ++ + ++++Q
Sbjct: 261 ELQSVSAKLQ------AQVEEN-ELWNRLNQQQ----EEKMWRQEEKIQEREEKIQEQEE 309
Query: 284 KLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEE 343
K++E+E ++ R + KE+++ ++ + + + ++ +E+ E+
Sbjct: 310 KIREQEEKM-------RRQEEMMWEKEEKMRRQEEMMWEKE------EKIRELEEKMHEQ 356
Query: 344 YPLTPETIMCYENKWEEPGHLTLDLQSQKQD----RHGEAGILNPIMEREEKFVTDEELH 399
E I E K +E + + Q+Q+ R E I E+EEK EE+
Sbjct: 357 -----EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK-----IREQEEKIREQEEMM 406
Query: 400 VVKQEV--EKLEDEWEREELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGE 457
++E E+ E WE+EE ++Q+EK + +EEK + + + I+ +++ E
Sbjct: 407 QEQEEKMGEQEEKMWEQEEEMQEQEEK--MRRQEEKIREQEKKIREQEEKIREQEEMMQE 464
Query: 458 EEERLKREMLLAKLNEIDRELQD 480
+EE++ + K+ E + ++Q+
Sbjct: 465 QEEKMGEQE--GKMCEQEAKMQE 485
Score = 50.4 bits (119), Expect = 5e-06
Identities = 71/325 (21%), Positives = 142/325 (43%), Gaps = 42/325 (12%)
Query: 172 KERLRKSQEKERATEKRVKDTESEL-FRTKFSLQKLKEIS-EARHLPER--------DDL 221
+E LR+ E + T + + ++EL +S +K++ EAR L R +L
Sbjct: 106 QEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGEL 165
Query: 222 AKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRL 281
+ L + + +R I+EL+K + + R + + E ++N LQ+++Q +
Sbjct: 166 EQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDE----ELKEKNAKLQEKLQLV 221
Query: 282 YHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKP 341
+ ++ E +L++K + K + K L ++ ++D + V +
Sbjct: 222 --ESEKSEIQLNVKEL------KRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 273
Query: 342 EEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVV 401
EE L E K + + + Q++ + I E+EEK EE+
Sbjct: 274 EENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEK------IREQEEKMRRQEEMMWE 327
Query: 402 KQEVEKLEDE--WEREE----LDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQ 455
K+E + ++E WE+EE L++K E+ + E+EEK + E I+ +K Q
Sbjct: 328 KEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEE--------KIREQEKRQ 379
Query: 456 GEEEERLKREMLLAKLNEIDRELQD 480
+E + ++E + + E RE ++
Sbjct: 380 EQEAKMWRQEEKIREQEEKIREQEE 404
Score = 37.0 bits (84), Expect = 0.062
Identities = 30/182 (16%), Positives = 84/182 (46%), Gaps = 19/182 (10%)
Query: 111 KINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITA 170
KI E + + E + K+ E ++ + QE+ + + E+ E + I +I
Sbjct: 398 KIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIRE 457
Query: 171 LKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAEL 230
+E +++ +EK E ++ + E+++ + +++ +E K+ E
Sbjct: 458 QEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEE---------------KIREQEK 502
Query: 231 KLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKER 290
K+ + E +I+E + ++ + ++ + ++ E ++ + +++++R K++E+E
Sbjct: 503 KIREQEEKIREQEEMMQ----EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEV 558
Query: 291 EL 292
L
Sbjct: 559 RL 560
Score = 35.4 bits (80), Expect = 0.18
Identities = 22/153 (14%), Positives = 74/153 (48%), Gaps = 8/153 (5%)
Query: 111 KINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITA 170
K+ E + E+ E + K+ ++ + ++ QE+ + + E+ E + + ++
Sbjct: 419 KMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCE 478
Query: 171 LKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAEL 230
+ ++++ +EK R E+++++ E ++ + +++ +E+ + + +K+ E
Sbjct: 479 QEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQE--------EKMWEQEE 530
Query: 231 KLDDTERRIKELSKNLELSTNSFQRQLLAERKR 263
K+ + E +++E + + + Q + R++
Sbjct: 531 KMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQ 563
Score = 35.4 bits (80), Expect = 0.18
Identities = 25/146 (17%), Positives = 71/146 (48%), Gaps = 8/146 (5%)
Query: 114 ELQNEVSELQVKLAELLKENKSLKRLQYR---QEKALNKFEDAENEISQLIFRHNNEITA 170
E+Q + +++ + ++ ++ K ++ + + QE+ + + E+ E + ++
Sbjct: 426 EMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQE 485
Query: 171 LKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKE--ISEARHLPERDDLAKKLVSA 228
+E++R+ +EK R EK++++ E ++ + +Q+ +E + + E+++ K+
Sbjct: 486 QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE---KMQEQ 542
Query: 229 ELKLDDTERRIKELSKNLELSTNSFQ 254
E K+ E +++E L Q
Sbjct: 543 EEKMRRQEEKMREQEVRLRQQEEKMQ 568
Score = 32.3 bits (72), Expect = 1.5
Identities = 17/98 (17%), Positives = 51/98 (52%)
Query: 111 KINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITA 170
K+ E + ++ E + K+ E ++ + + QEK + + E+ E +++ ++
Sbjct: 468 KMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 527
Query: 171 LKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKE 208
+E++ + +EK + E++++ E ++ + L++ +E
Sbjct: 528 QEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEE 565
>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
Length = 1233
Score = 65.9 bits (159), Expect = 1e-10
Identities = 107/446 (23%), Positives = 200/446 (44%), Gaps = 58/446 (13%)
Query: 107 ARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNN 166
AR++ + +++ V+L E +E + L L KA N F + + + ++
Sbjct: 95 ARVIVGGSSEYKINNKVVQLHEYSEELEKLGILI----KARN-FLVFQGAVESIAMKNPK 149
Query: 167 EITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEIS----EARHLPE----- 217
E TAL E + +S E + +KR K+ T+F+ + K I+ EA+ E
Sbjct: 150 ERTALFEEISRSGELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRY 209
Query: 218 ---RDDLAKKLVSAEL-KLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKV 273
+D++ + V +L KL E I++L+K L S +++ ++KR + DE K
Sbjct: 210 QRLKDEVVRAQVQLQLFKLYHNEVEIEKLNKELA----SKNKEIEKDKKRMDKVEDELKE 265
Query: 274 LQKEV-------QRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFA 326
+KE+ Q++ ++KEK+ EL+ K + +++ +K K+L K + +
Sbjct: 266 KKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKH 325
Query: 327 DLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGH-----LTLDLQSQKQDRH---GE 378
KG M++ + E + + +E + EE LTL+ ++Q + H E
Sbjct: 326 YKKRKG--DMDELEKEMLSV-EKARQEFEERMEEESQSQGRDLTLE-ENQVKKYHRLKEE 381
Query: 379 AGILNPIMERE-EKFVTDEELHVVKQEVEKLE-DEWEREELDKKQKEKASLLEREEKPEW 436
A + +E EKF D+ K + ++L+ +E ++ E + K K+K +E +K
Sbjct: 382 ASKRAATLAQELEKFNRDQ-----KADQDRLDLEERKKVETEAKIKQKLREIEENQKRIE 436
Query: 437 ETGRY-QLGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQDSRNLKYPVLPLLPDF 495
+ Y ++ KL+GE E + EM +++EI++EL V+ L D
Sbjct: 437 KLEEYITTSKQSLEEQKKLEGELTEEV--EMAKRRIDEINKELNQ-------VMEQLGDA 487
Query: 496 ESKLHSPERSPKTYRFSESSERLFNG 521
R + ES +RL+ G
Sbjct: 488 RIDRQESSRQQRKAEIMESIKRLYPG 513
Score = 55.5 bits (132), Expect = 2e-07
Identities = 66/345 (19%), Positives = 145/345 (42%), Gaps = 26/345 (7%)
Query: 47 RRKNPKRQTSDGQVHHQAPRKPSPKGLPNRKGVRVGFRSQSLNREPLRKDTDLVTKRILS 106
R+K + D Q ++ + + + ++ R Q L E +R L
Sbjct: 171 RKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKDEVVRAQVQL------- 223
Query: 107 ARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNN 166
+L K+ + E+ +L +LA +NK +++ + R +K ++ ++ + E+ +++
Sbjct: 224 -QLFKLYHNEVEIEKLNKELAS---KNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQ 279
Query: 167 EITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISE--ARHLPERDDLAKK 224
+KE+ + +K K ++T ++ + + + + L+ + + + D+L K+
Sbjct: 280 IEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKE 339
Query: 225 LVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHK 284
++S E + E R++E S++ + Q+ + EA L +E+++
Sbjct: 340 MLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRD 399
Query: 285 LKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEY 344
K + LD++ ++ + K+K + +N + T Q++E+ K E
Sbjct: 400 QKADQDRLDLEE--RKKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEG 457
Query: 345 PLTPETIMCYE-----NK-----WEEPGHLTLDLQ-SQKQDRHGE 378
LT E M NK E+ G +D Q S +Q R E
Sbjct: 458 ELTEEVEMAKRRIDEINKELNQVMEQLGDARIDRQESSRQQRKAE 502
Score = 50.1 bits (118), Expect = 7e-06
Identities = 67/346 (19%), Positives = 159/346 (45%), Gaps = 48/346 (13%)
Query: 102 KRILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLI 161
KRI+ +R ++ +L+ ++++++ ++ E ++ ++ +E+ + + +NEI++
Sbjct: 752 KRIIQSREREMKDLKEKMNQVEDEVFEEFCREIGVRNIREFEEEKVKR----QNEIAKKR 807
Query: 162 FRHNNEITAL-------KERLRKSQEKERATEKRVKDTESELFRTKFSLQK-LKEISEAR 213
N+ T L K +L++ Q+K E+ VK E+E+ + K Q+ +K I E
Sbjct: 808 LEFENQKTRLGIQLDFEKNQLKEDQDKVHMWEQTVKKDENEIEKLKKEEQRHMKIIDET- 866
Query: 214 HLPERDDLAKKLVSAELKLDDTERRIKELSKNL---ELSTNSFQRQLLA-ERKRAYEAHD 269
+ + DL + ++ + +++D ++E+ K L Q+++ A E K + D
Sbjct: 867 -MAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKEMTHLQKEVTAIETKLEQKRSD 925
Query: 270 ENKVLQK-EVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELA--LRKNAACQSDFA 326
+ +LQ ++Q + L + + DI + + S + + ++ + A + D+
Sbjct: 926 RHNLLQACKMQDIKLPLSKGTMD-DISQEEGSSQGEDSVSGSQRISSIYAREALIEIDYG 984
Query: 327 DLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIM 386
DLC + ++D + EE + ++ + +Q + + +L I
Sbjct: 985 DLC----EDLKDAQAEE-------------------EIKQEMNTLQQKLNEQQSVLQRIA 1021
Query: 387 EREEKFVTDEELHVVKQEVEKLEDEWE-REELDKKQKEKASLLERE 431
K + E+L V+ + ++ DE+E + KK K+ +++E
Sbjct: 1022 APNMKAM--EKLESVRDKFQETSDEFEAARKRAKKAKQAFEQIKKE 1065
Score = 35.8 bits (81), Expect = 0.14
Identities = 76/388 (19%), Positives = 153/388 (39%), Gaps = 85/388 (21%)
Query: 111 KINELQNEVSELQVKLAEL---LKENKSLKRLQYRQEKA-----LNKFEDAENEISQLIF 162
++ ++Q++ LQ++L L++ K+ QEK+ L F N+I ++I
Sbjct: 697 ELRQVQSQAHGLQMRLKYSQSDLEQTKTRHLALNLQEKSKLESELANFGPRINDIKRIIQ 756
Query: 163 RHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLA 222
E+ LKE++ + V+D E F + ++ ++E E + + ++++A
Sbjct: 757 SREREMKDLKEKMNQ-----------VEDEVFEEFCREIGVRNIREFEEEK-VKRQNEIA 804
Query: 223 KKLVSAE-------LKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKV-- 273
KK + E ++LD + ++KE + + + ++ DEN++
Sbjct: 805 KKRLEFENQKTRLGIQLDFEKNQLKEDQDKVHMWEQTVKK-------------DENEIEK 851
Query: 274 LQKEVQRLYHKLKEKEREL-DIKNIY-SNRLPKSSPNKEKELALRKNAACQSDFADLCTK 331
L+KE QR + E +L D+KN + + + + N E E +K + L
Sbjct: 852 LKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKEMTHL--- 908
Query: 332 GVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEK 391
+ + E K L+ ++ DRH +L ++ K
Sbjct: 909 ----------------QKEVTAIETK----------LEQKRSDRHN---LLQACKMQDIK 939
Query: 392 FVTDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNM 451
+ ++ + E + E+ + +S+ RE E + G +++
Sbjct: 940 LPLSKG---TMDDISQEEGSSQGEDSVSGSQRISSIYAREALIEIDYGDL------CEDL 990
Query: 452 DKLQGEEEERLKREMLLAKLNEIDRELQ 479
Q EEE + + L KLNE LQ
Sbjct: 991 KDAQAEEEIKQEMNTLQQKLNEQQSVLQ 1018
Score = 35.0 bits (79), Expect = 0.24
Identities = 55/303 (18%), Positives = 128/303 (42%), Gaps = 41/303 (13%)
Query: 144 EKALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTK--- 200
EKA++K ++ + +++ + + + + LR+ Q + + R+K ++S+L +TK
Sbjct: 668 EKAVDKLKEKKERLTEEL-KEQMKAKRKEAELRQVQSQAHGLQMRLKYSQSDLEQTKTRH 726
Query: 201 --FSLQKLKEISE--ARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQ 256
+LQ+ ++ A P +D+ + + S E ++ D + ++ ++ + F R+
Sbjct: 727 LALNLQEKSKLESELANFGPRINDIKRIIQSREREMKDLKEKMNQVEDEV---FEEFCRE 783
Query: 257 LLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALR 316
+ R +E +E Q E+ + + + ++ L I+ + K +K
Sbjct: 784 IGVRNIREFE--EEKVKRQNEIAKKRLEFENQKTRLGIQLDFEKNQLKEDQDKVHM---- 837
Query: 317 KNAACQSDFADLCTKGVQTMEDFKPEE---YPLTPETIMCYENKWEEPGHLTLDLQSQKQ 373
+ K +E K EE + ET+ + DL++Q
Sbjct: 838 --------WEQTVKKDENEIEKLKKEEQRHMKIIDETMAQLQ-----------DLKNQHL 878
Query: 374 DRHGEAGILNPIMEREEKFV--TDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLERE 431
+ E N ME K + ++E+ +++EV +E + E++ D+ +A ++
Sbjct: 879 AKKSEVNDKNHEMEEIRKKLGGANKEMTHLQKEVTAIETKLEQKRSDRHNLLQACKMQDI 938
Query: 432 EKP 434
+ P
Sbjct: 939 KLP 941
>gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens]
Length = 495
Score = 65.1 bits (157), Expect = 2e-10
Identities = 100/403 (24%), Positives = 180/403 (44%), Gaps = 66/403 (16%)
Query: 115 LQNEVSELQVKLA-ELLKENKSLKRLQYRQEKALN------KFEDAENEISQLIFRHNN- 166
LQNE EL ++ A + +ENK LK LQ +QE+ L K E ++E + R N+
Sbjct: 60 LQNEQFELDMEEAIQKAEENKRLKELQLKQEEKLAMELAKLKHESLKDEKMRQQVRENSI 119
Query: 167 EITALKERLRKS-QEKERATEKRVKDT--------ESELFRTKFSLQK--LKEISEARHL 215
E+ L+++L+ + KERA + KD ++E+ +T K +KE + A
Sbjct: 120 ELRELEKKLKAAYMNKERAAQIAEKDAIKYEQMKRDAEIAKTMMEEHKRIIKEENAAEDK 179
Query: 216 PERD------DLAKKLVSAELKLDDT-ERRIKELSKNLELSTNSFQRQLLAERKRAYEAH 268
+ DL K+L E K + E+ +KE E+ ++ L ++++ + +
Sbjct: 180 RNKAKAQYYLDLEKQLEEQEKKKQEAYEQLLKEKLMIDEIVRKIYEEDQLEKQQKLEKMN 239
Query: 269 DENKVLQ--KEVQRLYHKLKEKERELDIKNIY----------SNRLPKSSPNKEKELALR 316
+ ++ ++ Q L+ K K +E E + + I +R+ K N+EK L L
Sbjct: 240 AMRRYIEEFQKEQALWRKKKREEMEEENRKIIEFANMQQQREEDRMAKVQENEEKRLQL- 298
Query: 317 KNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQ-KQDR 375
+NA Q + + + +E + E Y E Y++K +E L Q + KQD
Sbjct: 299 QNALTQK--LEEMLRQREDLEQVRQELY--QEEQAEIYKSKLKEEAEKKLRKQKEMKQDF 354
Query: 376 HGEAG----ILNPIMEREE--------KFVTDEELHVV---KQEVEKLEDEWEREELDKK 420
+ +L E EE KF D+ + ++ KQ +++LE E+L ++
Sbjct: 355 EEQMALKELVLQAAKEEEENFRKTMLAKFAEDDRIELMNAQKQRMKQLEHRRAVEKLIEE 414
Query: 421 QKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERLK 463
++++ ++ E EW+ + + G EEERLK
Sbjct: 415 RRQQFLADKQRELEEWQLQQRRQGFINAI-------IEEERLK 450
Score = 37.0 bits (84), Expect = 0.062
Identities = 55/264 (20%), Positives = 113/264 (42%), Gaps = 29/264 (10%)
Query: 227 SAELKLDDTERRIKELSKNL--ELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHK 284
S L +ER K + +N +L + + R + + ++N+V +K+ RL
Sbjct: 3 SKRRNLSCSERHQKLVDENYCKKLHVQALKNVNSQIRNQMVQNENDNRVQRKQFLRL--- 59
Query: 285 LKEKERELDIKNIYSNRLPKSSPNKE-KELALRKNAACQSDFADLCTKGV------QTME 337
L+ ++ ELD++ + K+ NK KEL L++ + A L + + Q +
Sbjct: 60 LQNEQFELDMEEA----IQKAEENKRLKELQLKQEEKLAMELAKLKHESLKDEKMRQQVR 115
Query: 338 DFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEE 397
+ E L + Y NK D +Q + +A I +ME ++ + +E
Sbjct: 116 ENSIELRELEKKLKAAYMNKERAAQIAEKDAIKYEQMKR-DAEIAKTMMEEHKRIIKEEN 174
Query: 398 LHVVKQEVEKLEDEWERE-ELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQG 456
K+ K + + E +L++++K+K E+ K + +Y
Sbjct: 175 AAEDKRNKAKAQYYLDLEKQLEEQEKKKQEAYEQLLKEKLMIDEIVRKIY---------- 224
Query: 457 EEEERLKREMLLAKLNEIDRELQD 480
EE++L+++ L K+N + R +++
Sbjct: 225 -EEDQLEKQQKLEKMNAMRRYIEE 247
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 64.7 bits (156), Expect = 3e-10
Identities = 114/479 (23%), Positives = 214/479 (44%), Gaps = 53/479 (11%)
Query: 43 PASVRRKNPKRQTSDGQVHHQAPRKPSPKGLPNRKGVRVGFRSQSLNREPLRKDTDLVTK 102
P S R P + +G ++ + + SP P G S L+ E +R +
Sbjct: 1458 PGSPARDAPAEGSGEG-LNSPSTLECSPGSQPPSPGPATSPASPDLDPEAVRGALREFLQ 1516
Query: 103 RILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIF 162
+ SA+ + +EL+ + S L +LAE+ E S + +KA+ + E+A + +
Sbjct: 1517 ELRSAQRER-DELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLS 1575
Query: 163 RHNNEITALKERLRKSQEKERAT-------EKRVKDTESELFRTKFSLQKLKEISEARHL 215
E+ +E +R+S+ + RAT E+ ++ TESEL ++ + K+K +E +
Sbjct: 1576 GVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMK-ANETKLE 1634
Query: 216 PERDDLAKKLVSAE---LKLDDTERRIK-ELSKN-LELSTNSFQRQLLAER-----KRAY 265
++ L + L ++E +KL+ R ++ EL ++ L LS Q Q L +R ++
Sbjct: 1635 GDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVA 1694
Query: 266 EAHDENKVLQKEVQRL---YHKLKEKEREL-DIKNIYSNRLPKSSPN----KEKELALRK 317
++ + LQ V+RL K++E E L D + L +SS + ++K L L+K
Sbjct: 1695 DSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQK 1754
Query: 318 N-AACQSD---FADLCTKGVQTMEDFKPEE-------YPLTPETIMCYENKWEEPGHLTL 366
AC+ D + Q + + + + L E + E G L
Sbjct: 1755 ALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQ 1814
Query: 367 DLQSQKQDRHGEAGILNPIME-REEKFVTDEELHVVKQEVEKLEDEWEREELD--KKQKE 423
+ +Q + GEA LN + + ++E+ + E L +++ + +LE E E + +K+
Sbjct: 1815 LREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKD 1874
Query: 424 KASLLEREEKPEWETGRYQLGMYPIQNMDKLQ-GEEEERLKREMLLAKLN--EIDRELQ 479
+ +L +K E E R + D ++ E+ RL R + A+L E R++Q
Sbjct: 1875 RVALRRTLDKVEREKLR--------SHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQ 1925
Score = 50.4 bits (119), Expect = 5e-06
Identities = 109/498 (21%), Positives = 193/498 (38%), Gaps = 56/498 (11%)
Query: 46 VRRKNPKRQTSDGQVHHQAPRKPSPKGLPNRKGVRVGFRSQSLNR--EPLRKDTDLVTKR 103
+R++ K Q + ++ Q R + + G RV + +R E L ++ K
Sbjct: 622 LRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKE 681
Query: 104 ILSAR------LLKINELQNEVSELQVKL--AELLKENKSLKRLQYRQEKALNKFEDAEN 155
++ R L+ + LQ E +E+ L AE + L + R E+A +D+ +
Sbjct: 682 LVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEA--SLQDSLS 739
Query: 156 EISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHL 215
++S L + L + + +E++ A + R + E E + ++L+E+ + +
Sbjct: 740 KLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEV 799
Query: 216 PERDDLAKKLVSAELKLDDTERRIKELS---KNLELSTNSFQRQLLAERKRAYEAHDENK 272
R L L AE + E+++ L L+ RQL + +A E
Sbjct: 800 A-RQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARRE-- 856
Query: 273 VLQKEVQRLYHKLKEKER------ELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFA 326
Q++V+ L +EKE L ++ + + R ++ + L L K A S F
Sbjct: 857 -AQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLF- 914
Query: 327 DLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGE-AGILNPI 385
E + + E G L K+ GE AG+ I
Sbjct: 915 ----------------EVQRQLAQLEARREQLEAEGQALL---LAKETLTGELAGLRQQI 955
Query: 386 MEREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLEREEKPEWETGRYQLGM 445
+ +EK D+EL K + E + E +E L+RE++ W +L
Sbjct: 956 IATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWR----ELEA 1011
Query: 446 YPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQDSRNLKYPVLPLLPDFESKLHSPERS 505
Q +LQ E+EE L R L A+ E+ E+ + + L L + + S + S
Sbjct: 1012 ERAQLQSQLQREQEELLAR--LEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKES 1069
Query: 506 PKTYRFSESSERLFNGHH 523
KT SE+L H
Sbjct: 1070 EKT----ALSEKLMGTRH 1083
Score = 48.9 bits (115), Expect = 2e-05
Identities = 57/220 (25%), Positives = 105/220 (47%), Gaps = 19/220 (8%)
Query: 89 NREPLRKDTDLVTKRILSARLL------KINELQNEVSELQVKLAELLKENKSLKR-LQY 141
+R+ L++ D + + AR ++ L+ EV++L+++ E + + L+ L+
Sbjct: 1762 DRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQ 1821
Query: 142 RQE---KALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFR 198
RQE ALN + ++E L R + AL + + +E ER+ + KD + L R
Sbjct: 1822 RQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVA-LRR 1880
Query: 199 T--KFSLQKLKEISEARHLP-ERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQR 255
T K +KL+ + L E+ L + L AEL+L + +R+I++L + + S
Sbjct: 1881 TLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSP 1940
Query: 256 QLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIK 295
L +A + LQ+EV+RL + ER L+ +
Sbjct: 1941 AQLE-----VDAQQQQLELQQEVERLRSAQAQTERTLEAR 1975
Score = 48.5 bits (114), Expect = 2e-05
Identities = 91/421 (21%), Positives = 161/421 (38%), Gaps = 56/421 (13%)
Query: 95 KDTDLVTKRILSARLLKINELQNEVSELQV---KLAELLKENKSLKRLQYRQEKALNKFE 151
+D +R+ SA L E N LQV + EL +E + L+ Q + ++ E
Sbjct: 585 EDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLE 644
Query: 152 DAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISE 211
+ + + Q R E+ +L + + K K + + L R L+
Sbjct: 645 EEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQ---- 700
Query: 212 ARHLPERDDLAKKLVSA-----ELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYE 266
E+ ++A+ L A EL+L T+ R +E S LS S + LA+ K
Sbjct: 701 ----AEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKL--- 753
Query: 267 AHDENKV---LQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQS 323
D N++ L++E L + ++ E+E + RL +EL L + A Q
Sbjct: 754 --DLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERL--------EELRLEQEVARQG 803
Query: 324 DFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLT---LDLQSQKQDRHGEAG 380
L Q E + + L E E + L+ +L+ +++ +
Sbjct: 804 LEGSL-RVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVE 862
Query: 381 ILNPIMEREEKFVTDE-----ELHVVKQEVEKLEDEWEREELDKKQKEKASLLEREEKPE 435
L +E + +L ++E L +E R L+K+ E + + + +
Sbjct: 863 ALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQ 922
Query: 436 WETGRYQL---GMYPIQNMDKLQGE------------EEERLKREMLLAKLNEIDRELQD 480
E R QL G + + L GE E+ L +E++ KL + +RE Q
Sbjct: 923 LEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQA 982
Query: 481 S 481
S
Sbjct: 983 S 983
Score = 47.8 bits (112), Expect = 4e-05
Identities = 76/334 (22%), Positives = 146/334 (43%), Gaps = 50/334 (14%)
Query: 102 KRILSARLLKINELQNEVSELQVKLAELLKENKSLKR-LQYRQEKALNKFEDAENEISQL 160
++ LS + + L ++ + LA + E + KR Q RQE+ + +E+ L
Sbjct: 1061 QQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDL 1120
Query: 161 IFRHNNEITALKERLRKSQEKERATEKRVKDT---ESELFRTKFSLQKLKEISEARHLPE 217
+ A + +R+ QE+ R K+ +D+ E+E RT+ L +
Sbjct: 1121 RAQREEAAAAHAQEVRRLQEQARDLGKQ-RDSCLREAEELRTQLRLLE----------DA 1169
Query: 218 RDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAY-EAHDENKVLQK 276
RD L ++L+ A +R+++E + E+ QRQ E +R+ E E + L++
Sbjct: 1170 RDGLRRELLEA-------QRKLRESQEGREV-----QRQEAGELRRSLGEGAKEREALRR 1217
Query: 277 EVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNA--ACQSDFADLCTKGVQ 334
+ L +K+ E E L ++ +KE++LAL + A A + +L T G+Q
Sbjct: 1218 SNEELRSAVKKAESE-------RISLKLANEDKEQKLALLEEARTAVGKEAGELRT-GLQ 1269
Query: 335 TME-----------DFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILN 383
+E + + + L E E G L L +++K+ R G+
Sbjct: 1270 EVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQ 1329
Query: 384 PIMEREEKF-VTDEELHVVKQEVEKLEDEWEREE 416
+++ E V +EL V ++++++ E E+ E
Sbjct: 1330 RLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRE 1363
Score = 35.4 bits (80), Expect = 0.18
Identities = 43/201 (21%), Positives = 93/201 (46%), Gaps = 17/201 (8%)
Query: 90 REPLRKDTDLVTKRILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNK 149
R+ L + V++R+ A L+ EL+ + V+ + L+ ++ YR++ L
Sbjct: 104 RDELAIKYNAVSERLEQALRLEPGELETQEPRGLVRQSVELRRQLQEEQASYRRK--LQA 161
Query: 150 FEDAENEISQLIFRHNNEITALKERLRKSQEK--ERATE---KRVKDTESELFRTKFSLQ 204
+++ + +QL+ R +I K+R + +++ ER+ E +R++DTE ++
Sbjct: 162 YQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLERSGELEQQRLRDTEHSQDLESALIR 221
Query: 205 KLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQ--RQLLAERK 262
+E + L + + + ++ +LD + LS+++ TN + R+ L R+
Sbjct: 222 LEEEQQRSASLAQVNAMLRE------QLDQAGSANQALSEDIRKVTNDWTRCRKELEHRE 275
Query: 263 RAYEAHDE--NKVLQKEVQRL 281
A+ +E N E RL
Sbjct: 276 AAWRREEESFNAYFSNEHSRL 296
Score = 34.3 bits (77), Expect = 0.40
Identities = 69/332 (20%), Positives = 133/332 (40%), Gaps = 34/332 (10%)
Query: 157 ISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEIS------ 210
I + + ++ ++ R SQ+ K++ D+ESE + LQ+L++ +
Sbjct: 524 IHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQA 583
Query: 211 --EARHLPERDDLAKKLVSAEL-----KLDDTERRIKELSKNLELSTNSFQRQLLAERKR 263
+A+ +R A +L+S E L +++ +EL + E + Q +L +R R
Sbjct: 584 HEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQERE-KLQAAQEELRRQRDR 642
Query: 264 AYE----AHDENKVLQKEVQRLYHKLKEKE--RELDIKNIYSNRLPKSSPNKEKELALRK 317
E A + +++E++R + +L++ E R + K + R S ++++ +
Sbjct: 643 LEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAE 702
Query: 318 NAACQSDFADLCTKGVQ-------TMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQS 370
A + A+ TK +M + EE L +++ E LDL
Sbjct: 703 KA----EVAEALTKAEAGRVELELSMTKLRAEEASL-QDSLSKLSALNESLAQDKLDLNR 757
Query: 371 QKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQK--EKASLL 428
E L + E+ T + E +LE E R+ L+ + E+A
Sbjct: 758 LVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEA 817
Query: 429 EREEKPEWETGRYQLGMYPIQNMDKLQGEEEE 460
++ P R QL Q +L G E+E
Sbjct: 818 LEQQLPTLRHERSQLQEQLAQLSRQLSGREQE 849
Score = 29.6 bits (65), Expect = 9.9
Identities = 32/137 (23%), Positives = 60/137 (43%), Gaps = 19/137 (13%)
Query: 88 LNREPLRKDTDLVT--------KRILSARLLKINELQNEVSELQVKLAELLKENKSLKRL 139
+ RE LR D V R L+ L++ E Q ++ +L+ ++ +L+++ S +L
Sbjct: 1885 VEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVV-VLEQSHSPAQL 1943
Query: 140 QYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRT 199
+ DA+ + +L +A + R + +ERA +RV+ E ++
Sbjct: 1944 EV----------DAQQQQLELQQEVERLRSAQAQTERTLEARERAHRQRVRGLEEQVSTL 1993
Query: 200 KFSLQKLKEISEARHLP 216
K LQ+ S A P
Sbjct: 1994 KGQLQQELRRSSAPFSP 2010
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 64.3 bits (155), Expect = 4e-10
Identities = 129/613 (21%), Positives = 259/613 (42%), Gaps = 82/613 (13%)
Query: 39 VSSSPASVRRKNPKRQTSDGQVHHQAPRKPSPKGLPNRKGVRVGFRSQSLNREPLRKDTD 98
VSS+ + + +K+ + Q++ Q S K + + V Q L L+
Sbjct: 1325 VSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQ---- 1380
Query: 99 LVTKRILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEIS 158
A L + ELQ ++ ELQ KL +E+ S Q L++ E A +I
Sbjct: 1381 -------IAGLEHLRELQPKLDELQ-KLISKKEEDVSYLSGQ------LSEKEAALTKIQ 1426
Query: 159 QLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPER 218
I + I AL +L + Q KE ++R+K + EL K QK +EI E +
Sbjct: 1427 TEIIEQEDLIKALHTQL-EMQAKEH--DERIKQLQVELCEMK---QKPEEIGEESR--AK 1478
Query: 219 DDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQR--QLLAERKRAYEAHDENK---- 272
+ +KL +A + + + K L + L L+ + +R + LA+ + A ++ K
Sbjct: 1479 QQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVL 1538
Query: 273 ----VLQKEVQRLYHKLKEK--ERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFA 326
+LQ+E +L ++ E + + S +L ++KE +++ + +S
Sbjct: 1539 GRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKI 1598
Query: 327 DLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIM 386
T+ + ++ + +EY + ++ N+ E H+ ++ +KQ+ +G+
Sbjct: 1599 AESTEWQEKHKELQ-KEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLR-----S 1652
Query: 387 EREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQK-----EKASLLEREEKPEWETGRY 441
K T+++L +QE+E+++++ + K+QK E+ L E P +T +
Sbjct: 1653 TEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKE 1712
Query: 442 QLGMYPIQNMDKLQGEEEERLKRE---------MLLAKLNEIDRELQDSRNLKYPVLPLL 492
M + + + EE ER+K E L+++ + + E+QD LK+ + +
Sbjct: 1713 --CMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQD---LKHQIEGNV 1767
Query: 493 PDFESKLHSPERSPKTYRFSESSERLFNGHHLQDISFSTPK----GEGQNSGNVRSPASP 548
++ L + E+ +E + G + S S E S +PA
Sbjct: 1768 SK-QANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVS 1826
Query: 549 NEFA----FGSYVPSFAKTSERSNPFSQK-------SSFLDFQRNSM--EKLSKDG-VDL 594
+F+ +Y+ + ER ++ S L+ ++N++ + +KDG + +
Sbjct: 1827 KDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKM 1886
Query: 595 ITRKEKKANLMEQ 607
+ + K NL+ Q
Sbjct: 1887 LQEEVTKMNLLNQ 1899
Score = 55.1 bits (131), Expect = 2e-07
Identities = 86/418 (20%), Positives = 175/418 (41%), Gaps = 48/418 (11%)
Query: 114 ELQNEVSELQV-KLAELLKENKSLKRLQYRQEKALNKFEDAENE---ISQLIFRHNNEIT 169
+L E+ L+ K+AE + + K LQ E L +E+ NE I ++ E
Sbjct: 1585 KLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQ 1644
Query: 170 ALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAE 229
L +LR ++ ++ TEK++++ E E+ K ++K + S+ + + E ++ +L +
Sbjct: 1645 ELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAK-SKQQKILELEEENDRLRAEV 1703
Query: 230 LKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEA--------HDENKVLQKEVQRL 281
DT + E LS+N+ ++ L K YE E L +EVQ L
Sbjct: 1704 HPAGDTAKECMETL----LSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDL 1759
Query: 282 YHKLK---EKERELDIKNIYSNRL------PKSSPNKEKE---LALRKNAACQSDFADLC 329
H+++ K+ L+ + N+ +S P + +E L++ C
Sbjct: 1760 KHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAK 1819
Query: 330 TKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMERE 389
+ +DF + + I Y + ++ L+ +KQ + +E E
Sbjct: 1820 SANPAVSKDFS------SHDEINNYLQQIDQLKERIAGLEEEKQKNKE----FSQTLENE 1869
Query: 390 EKFV------TDEELHVVKQEVEKLE--DEWEREELDKKQKEKASLLEREEKPEWETGRY 441
+ + D EL ++++EV K+ ++ +EEL + K K + E ++ E E
Sbjct: 1870 KNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLE-ERLMN 1928
Query: 442 QLGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQDSRNLKYPVLPLLPDFESKL 499
QL + Q + ++K E+L +++ + + + + K ++ ES++
Sbjct: 1929 QLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEI 1986
Score = 53.1 bits (126), Expect = 8e-07
Identities = 78/425 (18%), Positives = 178/425 (41%), Gaps = 54/425 (12%)
Query: 86 QSLNREPLRKDTDLVTKRILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEK 145
Q +EP K + +L + ++ +LQ + Q K++ L +++K L++ Q +
Sbjct: 1995 QGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISAL---ERTVKALEFVQTE 2051
Query: 146 ALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQK 205
+ E + ++Q + E +K+Q + + + + DT+SE R K
Sbjct: 2052 SQKDLEITKENLAQAV-----------EHRKKAQAELASFKVLLDDTQSEAARVLADNLK 2100
Query: 206 LKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAY 265
LK+ ++ + + +K E +L+ E + + KN++ ++ +R+ + +
Sbjct: 2101 LKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIG 2160
Query: 266 EAHDENKVLQKEVQRLYHKL------------------KEKERELDIKNIYSNRLPKSSP 307
E KEVQ+L L +++R +D + + +
Sbjct: 2161 EIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQ 2220
Query: 308 NKEKELALRKNAACQSDFADLCT--KGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLT 365
+KE+E+ L++ D C+ K EE + + + WE
Sbjct: 2221 SKEEEIRLKE---------DNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTE 2271
Query: 366 LDLQSQKQDR-HGE-AGILNPIMEREEKFVTDE-ELHVVKQEVEKLEDEWE--REELDKK 420
+ LQ + D GE +L+ + E + + + EL ++ E++ L+D+ L+K
Sbjct: 2272 VQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKC 2331
Query: 421 QKEKASL--LEREEKPEWETGR--YQLGMYPIQNMDKLQG--EEEERLKREMLLAKLNEI 474
+++K +L + R+++ + + + Y+ +Q +L EE +K + +++ L+
Sbjct: 2332 KEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGK 2391
Query: 475 DRELQ 479
+ +Q
Sbjct: 2392 EEAIQ 2396
Score = 53.1 bits (126), Expect = 8e-07
Identities = 106/483 (21%), Positives = 195/483 (40%), Gaps = 117/483 (24%)
Query: 86 QSLNREPLRKDTDLVTKRILSARLLKINELQNEVSELQVKLAELLKENKSLKR----LQY 141
+ LN+ KD+ K++L +L + EL+N+ ++L+ KL E + N+ L+R LQ
Sbjct: 2538 EDLNQVITIKDSQ--QKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQE 2595
Query: 142 RQEKALNKFEDAENEISQLIFRHNNEITALKE---------RLRKSQEKER-------AT 185
++ + E + ISQL ++TAL+E +L+ +E+ ++
Sbjct: 2596 EKQDLSKEIESLKVSISQL----TRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSS 2651
Query: 186 EKRVKDTESELFRT-KFSLQKLKEI-----SEARHLPERDDLAKKLVSAELKLDDTERRI 239
+KR+ + E EL K + +K+ EI E +HL + + + + E R+
Sbjct: 2652 QKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRN------ETETAEERV 2705
Query: 240 KELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYS 299
EL+++L +++LL K ENK L ++Q + + D N
Sbjct: 2706 AELARDLV----EMEQKLLMVTK-------ENKGLTAQIQSFGRSMSSLQNSRDHANEEL 2754
Query: 300 NRLPKSSPNKEKELA-LRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKW 358
+ L + KELA L++ + L ++ +M + + +K
Sbjct: 2755 DELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKD 2814
Query: 359 EEPGHLTLDLQSQKQDRHGEAGILNPIM-----ERE------EKFVTDE----------- 396
E+ L L SQ +D + + + M ER+ EKF E
Sbjct: 2815 EQ----LLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPS 2870
Query: 397 ----ELHVVKQEVEKLEDEWER--EELDKKQKE--------------KASLLE------- 429
E+ +K+ + L+++ +R +EL Q++ KA L E
Sbjct: 2871 TSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTKA 2930
Query: 430 --------REEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQDS 481
R+E W+ +QL M+K E ER +E L +++ D++L
Sbjct: 2931 FQIMQEELRQENLSWQHELHQL------RMEKSSWEIHERRMKEQYLMAISDKDQQLSHL 2984
Query: 482 RNL 484
+NL
Sbjct: 2985 QNL 2987
Score = 46.6 bits (109), Expect = 8e-05
Identities = 72/330 (21%), Positives = 141/330 (42%), Gaps = 37/330 (11%)
Query: 116 QNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITAL---K 172
Q ++ AE+ K++ LQ +++ L + ++ + + Q+ N EIT L K
Sbjct: 2863 QRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQI----NQEITELHPLK 2918
Query: 173 ERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELK- 231
+L++ Q+K +A + ++ E + L +L+ + + ER + L++ K
Sbjct: 2919 AQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMKEQYLMAISDKD 2978
Query: 232 -----LDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQR--LYHK 284
L + R ++ S + +QRQ E + + +N V + E+ R L
Sbjct: 2979 QQLSHLQNLIRELRSSSSQTQPLKVQYQRQASPETSASPDG-SQNLVYETELLRTQLNDS 3037
Query: 285 LKE-KERELDIKNIYSN--RLPKSSPNKEKEL-----ALRKNAACQSDFADLCT---KGV 333
LKE ++EL I+ + SN +L + +L +LR+N D + C K V
Sbjct: 3038 LKEIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHCAVLEKQV 3097
Query: 334 QTME--DFKPEEYPLTPETIMCYENKWE-----EPGHLTLDLQSQKQDRHGEAGILNPIM 386
Q ++ + P P+ K + EP + Q Q + E L ++
Sbjct: 3098 QELQAGPLNIDVAPGAPQEKNGVHRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLL 3157
Query: 387 E--REEKFVTDEELHVVKQEVEKLE-DEWE 413
E R+++ + L V ++++ +LE EW+
Sbjct: 3158 EEERDQRVAAENALSVAEEQIRRLEHSEWD 3187
Score = 43.1 bits (100), Expect = 9e-04
Identities = 86/411 (20%), Positives = 168/411 (40%), Gaps = 51/411 (12%)
Query: 96 DTDLVTKRILSARLLK---------INELQNEVSELQVKLAELLKEN-KSLKRLQ--YRQ 143
+TDL R L++RL + I+ L + +QV +AEL +++ K +K L+ Q
Sbjct: 2360 ETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQ 2419
Query: 144 EKALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTES---ELFRTK 200
E+ N + EN+ + + + N + LK +++ +++ + VK S + R
Sbjct: 2420 EEEENIVLEEENK--KAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIV 2477
Query: 201 FSLQKLKEISEARHLP---ERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQL 257
Q+L+E RHL E+D L ++ + KL + R ++ +L +L
Sbjct: 2478 GDYQQLEE----RHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAEL 2533
Query: 258 L--------------AERKRAYEAH-DENKVLQKEVQRLYHKLKEKERELDIKNIYSNRL 302
+ +++K+ E +NK L+ + +L KLKE E + N L
Sbjct: 2534 IQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNAL 2593
Query: 303 PKSSPNKEKELALRKNAACQ-----SDFADLCTKGVQTME-DFKPEEYPLTPETIMCYEN 356
+ + KE+ K + Q + + T G+ + K EE + +
Sbjct: 2594 QEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEE---VHRLSALFSS 2650
Query: 357 KWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREE 416
+ L +L +++ + G + +++E K + + +++ E E E+
Sbjct: 2651 SQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHL-HHDAGIMRNETETAEERVAELA 2709
Query: 417 LDKKQKEKASLLEREEKPEWETGRYQLG--MYPIQNMDKLQGEEEERLKRE 465
D + E+ L+ +E G M +QN EE + LKR+
Sbjct: 2710 RDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRK 2760
Score = 42.4 bits (98), Expect = 0.001
Identities = 96/495 (19%), Positives = 198/495 (40%), Gaps = 91/495 (18%)
Query: 105 LSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNK----------FEDAE 154
LS LL++ E Q E++ L+++L E + L ++ K + F +
Sbjct: 559 LSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQMEGEGIAPIKMKVFLEDT 618
Query: 155 NEISQLIFRHNNEITALKERLRKSQEKERATEK-RVKDTESELFRTKF----SLQKLKEI 209
+ L+ + + A+++ ++ + R +E+ + D EL TK SL + +I
Sbjct: 619 GQDFPLMPNEESSLPAVEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDI 678
Query: 210 SEARHLPERDDLAKKLVSAEL------------------KLDDTERRIKELSKNLELSTN 251
+ H E + L +++ EL ++ + + I+E KN + +++
Sbjct: 679 GQC-HQDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSS 737
Query: 252 SF------QRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERE-------------L 292
+F + QLL++ K + L+ +V++L L E ER+ L
Sbjct: 738 AFTALSEERDQLLSQVKELSMVTE----LRAQVKQLEMNLAEAERQRRLDYESQTAHDNL 793
Query: 293 DIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCT--KGVQTMEDFKPEEYPLTPET 350
+ I+S + S + + E+ + Q F++ T + +Q+ K E E
Sbjct: 794 LTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAER 853
Query: 351 IMCYENKWEEPGHLTL--DLQSQKQD-----RHGEAGILNPIMEREEKFVTDEELHVVKQ 403
+ +K EE +L+ K D + + L +E +++ VT+ + ++
Sbjct: 854 VRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEK 913
Query: 404 EVEKLEDEWEREELDKKQKEKASLLEREEKPEWE-------------------TGRYQLG 444
V+ E+++ K KE+ +LL R E+ + E + Q+
Sbjct: 914 MVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQIS 973
Query: 445 MYPIQNMDKLQGEEEERLKREMLLAKLN------EIDRELQDSRNLKYPVLPLLPDFESK 498
+Q+ L +E E+ KR++ A +N + R ++ NLK +P E++
Sbjct: 974 KEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETE 1033
Query: 499 LHSPERSPKTYRFSE 513
E + +SE
Sbjct: 1034 RGEVEEDKENKEYSE 1048
Score = 38.5 bits (88), Expect = 0.021
Identities = 56/309 (18%), Positives = 131/309 (42%), Gaps = 18/309 (5%)
Query: 111 KINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITA 170
+++++Q + SE + L + ++ + + + E+SQ + + EIT
Sbjct: 818 ELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITK 877
Query: 171 LKERLRKSQEKERATEKRVKDTESELFRTKFSL-QKLKEISEARHLPERDDLAKKLVSAE 229
+ + L + + ++ +++ + ++ FS+ +K+ +++E + + K + +
Sbjct: 878 MDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKF---SLGVEIKTLKEQ 934
Query: 230 LKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKE 289
L L K+ + +S +Q E A + E LQ E L + ++++
Sbjct: 935 LNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEE--LQHEFDLLKKENEQRK 992
Query: 290 RELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPE 349
R+L I L + E+ELA K+ + + + T+ + ED + +EY
Sbjct: 993 RKLQAALINRKELLQRVSRLEEELANLKDES-KKEIPLSETERGEVEEDKENKEYSEKCV 1051
Query: 350 TIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELH-VVKQEVEKL 408
T C E +++ ++ E + + + EEK +E+ +VKQ + L
Sbjct: 1052 TSKCQE----------IEIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTL 1101
Query: 409 EDEWEREEL 417
+D+ + +L
Sbjct: 1102 QDKTNQIDL 1110
Score = 36.6 bits (83), Expect = 0.081
Identities = 63/311 (20%), Positives = 123/311 (39%), Gaps = 59/311 (18%)
Query: 179 QEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERR 238
QE+ E+ V + + + + LQ+ E + + + K + A+ KL +
Sbjct: 51 QERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTSLNKY 110
Query: 239 IKELSKN--LELSTNSFQRQLLAERKRAYEAHDENKVLQK-EVQRLYHKLKEKERELDIK 295
I+E+ L T + L++ HD++ ++ E++++ HKL+EKE
Sbjct: 111 IEEMKAQGGTVLPTEPQSEEQLSK-------HDKSSTEEEMEIEKIKHKLQEKE------ 157
Query: 296 NIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYE 355
EL A A+ + ME+F + +
Sbjct: 158 ----------------ELISTLQAQLTQAQAEQPAQSSTEMEEF------------VMMK 189
Query: 356 NKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWERE 415
+ +E LQ+Q E + E++ +F T LH + E+ +L +
Sbjct: 190 QQLQEKEEFISTLQAQLSQTQAEQAAQQVVREKDARFETQVRLH--EDELLQLVTQ---A 244
Query: 416 ELDKKQKEKASLLER--EEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLA-KLN 472
+++ + ++K +L+R EE E GR Q+ +D LQ E +R +L+ +L
Sbjct: 245 DVETEMQQKLRVLQRKLEEHEESLVGRAQV-------VDLLQQELTAAEQRNQILSQQLQ 297
Query: 473 EIDRELQDSRN 483
+++ E RN
Sbjct: 298 QMEAEHNTLRN 308
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 62.8 bits (151), Expect = 1e-09
Identities = 94/391 (24%), Positives = 172/391 (43%), Gaps = 50/391 (12%)
Query: 114 ELQNEVSELQVKLAELLKENKSLKRLQYRQEK---ALNKFEDAENEISQLIFRHNNEITA 170
+++N+++ + LA+ L+ K LQ ++E+ A+ + + Q I I
Sbjct: 518 QIRNQLTAMSSVLAKALEVIKPAHILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEE 577
Query: 171 LKERL--------RKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLA 222
KERL ++ E+ A ++V+ E E R Q+ KE + R L E + +
Sbjct: 578 RKERLESLNIQREKEELEQREAELQKVRKAEEERLR-----QEAKEREKERILQEHEQIK 632
Query: 223 KKLVSAELKLDDTERRIKELSKNLELSTNSFQR---QLLAERKRAYEAHDENKVLQKEVQ 279
KK V L E K EL +F+ + L E + + + L+KE +
Sbjct: 633 KKTVRERL----------EQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKK 682
Query: 280 RLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDF 339
L +LK +E+++D Y R + +E+ L K+A + D+ Q E+
Sbjct: 683 ELQERLKNQEKKID----YFERAKRL-----EEIPLIKSAYEEQRIKDMDLWEQQ--EEE 731
Query: 340 KPEEYPLTPETIMCYENKW----EEPGHLTLDLQSQKQDRHGEAGILNPIMER--EEKFV 393
+ L E + ++N+ E+ + L++ +Q + E L ER EE+
Sbjct: 732 RITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEK--LKQFEERLAEERHN 789
Query: 394 TDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMDK 453
EE ++E ++ E+EE ++++ E+ L EREE+ E + + + Q K
Sbjct: 790 RLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVK 849
Query: 454 LQGEEEERLKREMLLAKLNEIDRELQDSRNL 484
+ EE ER KR+ L ++ E +R ++ R L
Sbjct: 850 -KLEEVERKKRQREL-EIEERERRREEERRL 878
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 62.8 bits (151), Expect = 1e-09
Identities = 93/401 (23%), Positives = 172/401 (42%), Gaps = 62/401 (15%)
Query: 96 DTDLVTKRILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFE-DAE 154
+T L T+++ + K+ + E + +KL LKE + + + K LN E +
Sbjct: 1127 ETILETQKVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLK 1186
Query: 155 NEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARH 214
EI+QL N + +K L+ +E+E + + + EL + Q LK + +
Sbjct: 1187 EEITQL----TNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKE 1242
Query: 215 LPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVL 274
+D A + KL D +++IK++ K + + DE+K+L
Sbjct: 1243 ----EDYA----DLKEKLTDAKKQIKQVQKEVSVM------------------RDEDKLL 1276
Query: 275 QKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRK-NAACQSDFADLCTKGV 333
+ ++ L K + +ELD+K +L + N++ E A+++ AC+ ++ K +
Sbjct: 1277 RIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKD--LNVKEKII 1334
Query: 334 QTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFV 393
+ M E+ E E K EE L +L+ K+ + N +E +
Sbjct: 1335 EDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNKEHENN 1394
Query: 394 TDEELHVVKQEVEKLEDEWEREE----LDKKQ--KEKASLLEREEKPEWETGRYQLGMYP 447
TD V ++ L+DE + E D+K+ +EK L+ + ++ E
Sbjct: 1395 TD-----VLGKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAKEAE-----------N 1438
Query: 448 IQNMD-KLQGEEEERL-----KREMLLAKLNEIDRELQDSR 482
I+N + K E+ ER + E+L A+L E D +LQ R
Sbjct: 1439 IRNKEMKKYAEDRERFFKQQNEMEILTAQLTEKDSDLQKWR 1479
Score = 48.9 bits (115), Expect = 2e-05
Identities = 82/377 (21%), Positives = 161/377 (42%), Gaps = 60/377 (15%)
Query: 111 KINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITA 170
+I EL+ ++ +LQ ++ EN LK +++ + L K + E I QL +
Sbjct: 1037 QIEELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLK--EKETLIQQLKEELQEKNVT 1094
Query: 171 LKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAEL 230
L +++ E +RA + + K +++L+ I E + + + SA+L
Sbjct: 1095 LDVQIQHVVEGKRALSELTQGVTC----YKAKIKELETILETQKV-------ECSHSAKL 1143
Query: 231 KLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKER 290
+ D E+ + + LE + FQ L K + + + L++E+ +L + L++ +
Sbjct: 1144 EQDILEK--ESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKH 1201
Query: 291 ELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPET 350
L +K + K KE +A Q+ ADL K ED+ + LT
Sbjct: 1202 LLQLKE-EEEETNRQETEKLKEELSASSARTQNLKADLQRK----EEDYADLKEKLT--- 1253
Query: 351 IMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLED 410
D + Q + E ++ R+E D+ L + E+EK ++
Sbjct: 1254 ----------------DAKKQIKQVQKEVSVM-----RDE----DKLLRIKINELEKKKN 1288
Query: 411 EWEREELDKKQKEKASLLER--EEKPEWETGRYQLGMYPIQNMDK--------LQGEEEE 460
+ +ELD KQ+ L E+ +K E +Y+ + +K L+ +E+
Sbjct: 1289 QCS-QELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQT 1347
Query: 461 RLKREMLL-AKLNEIDR 476
+++++ +L AKL E++R
Sbjct: 1348 QVEQDQVLEAKLEEVER 1364
Score = 46.6 bits (109), Expect = 8e-05
Identities = 94/414 (22%), Positives = 169/414 (40%), Gaps = 58/414 (14%)
Query: 105 LSARLLKI-NELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFR 163
L A LL I NEL+NE E AEL NK + Q + K E+ Q+
Sbjct: 847 LRAFLLTIENELKNEKEEK----AEL---NKQIVHFQQELSLSEKKNLTLSKEVQQIQSN 899
Query: 164 HNNEITALKERLRKSQEKERATEKRVKDTES------------ELFRTKFSLQKLKEISE 211
++ I L + K+QE+E K + E+ +L TK + +L+ +
Sbjct: 900 YDIAIAELHVQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTK--IDELRTLDS 957
Query: 212 ARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAH--- 268
+ D L + +S + D+ +L N L + + + E R H
Sbjct: 958 VSQISNIDLLNLRDLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQEPNRENSFHSSI 1017
Query: 269 ----DENKVLQKEVQRLYHKLKEKEREL-----DIKNI--YSNRLPKSSPNKEKELALRK 317
+E K + K + H+++E E+++ ++K +NRL + + +L K
Sbjct: 1018 EAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEK 1077
Query: 318 NAACQSDFADLCTKGV------QTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQ 371
Q +L K V Q + + K LT + + CY+ K +E L L++Q
Sbjct: 1078 ETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSELT-QGVTCYKAKIKE---LETILETQ 1133
Query: 372 KQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLERE 431
K + A + I+E+E + ++E+ E++ E L K L +E
Sbjct: 1134 KVECSHSAKLEQDILEKES----------IILKLERNLKEFQ-EHLQDSVKNTKDLNVKE 1182
Query: 432 EKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQDSRNLK 485
K + E + + ++++ +L+ EEEE ++E K E+ ++NLK
Sbjct: 1183 LKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLK-EELSASSARTQNLK 1235
Score = 35.4 bits (80), Expect = 0.18
Identities = 55/241 (22%), Positives = 106/241 (43%), Gaps = 26/241 (10%)
Query: 90 REPLRKD---TDLVTKRILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKA 146
RE KD T + T+ + LK N+++ E+++ + EL+K + LK+ + +
Sbjct: 652 REEAAKDICATKVETEEATACLELKFNQIKAELAKTK---GELIKTKEELKKRENESDSL 708
Query: 147 LNKFEDAENEI---SQLIFRHNNEITALKERLRKSQEKERATEKRVK-----DTESELFR 198
+ + E + +I +Q I N I ++ + + Q + E K DT S +
Sbjct: 709 IQELETSNKKIITQNQRIKELINIIDQKEDTINEFQNLKSHMENTFKCNDKADTSSLIIN 768
Query: 199 TKFSLQKLKEI---SEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQR 255
K + E+ S+++ ER K++ EL+ D+ + ++ +S+ +
Sbjct: 769 NKLICNETVEVPKDSKSKICSER----KRVNENELQQDEPPAK----KGSIHVSSAITED 820
Query: 256 QLLAERKRAYEAHDEN-KVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELA 314
Q +E R A E+ +VLQ+ + L L E EL + L K + ++EL+
Sbjct: 821 QKKSEEVRPNIAEIEDIRVLQENNEGLRAFLLTIENELKNEKEEKAELNKQIVHFQQELS 880
Query: 315 L 315
L
Sbjct: 881 L 881
Score = 30.8 bits (68), Expect = 4.4
Identities = 57/266 (21%), Positives = 98/266 (36%), Gaps = 77/266 (28%)
Query: 131 KENKSLKRLQYRQEKALNKFEDAEN---------EISQLIFRHNNEITALK--------- 172
+++K + + +R+ K + F+ N ISQ ++ + LK
Sbjct: 421 EKSKFQQHVPFRESKLTHYFQSFFNGKGKICMIVNISQCYLAYDETLNVLKFSAIAQKVC 480
Query: 173 --ERLRKSQEKERATEKRVKD------TESELFRTKFSL----QKLKEISEARHLPERDD 220
+ L SQEK K +D + S++ K + L+++ E L E +
Sbjct: 481 VPDTLNSSQEKLFGPVKSSQDVSLDSNSNSKILNVKRATISWENSLEDLMEDEDLVEELE 540
Query: 221 LAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQR 280
A++ + E KL D ++L K LE +A+ +H+E + L ++
Sbjct: 541 NAEETQNVETKLLD-----EDLDKTLE-------------ENKAFISHEEKRKLLDLIED 582
Query: 281 LYHKL----KEK--------------------ERELDIKNIYSNRLPKSSPNKEKELALR 316
L KL KEK +RE D K N E+ LA+
Sbjct: 583 LKKKLINEKKEKLTLEFKIREEVTQEFTQYWAQREADFKETLLQEREILEENAERRLAIF 642
Query: 317 KNAACQSD-----FADLCTKGVQTME 337
K+ + D D+C V+T E
Sbjct: 643 KDLVGKCDTREEAAKDICATKVETEE 668
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 62.0 bits (149), Expect = 2e-09
Identities = 78/365 (21%), Positives = 163/365 (44%), Gaps = 68/365 (18%)
Query: 110 LKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEIT 169
++ + L E+ + KL ++EN+ L +QE+ + + E+ E + + +I
Sbjct: 262 VEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIR 321
Query: 170 ALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAE 229
+E++ + +EK E+++++ E +++R + +K++E E K+ E
Sbjct: 322 EQEEKMWRQEEKMHEQEEKIREQEDKMWRQE---EKIREQEE------------KIREQE 366
Query: 230 LKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKE 289
K+ E +I+E + ++ RQ R++ + ++ +K+++ K++E+E
Sbjct: 367 EKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQE 426
Query: 290 RELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPE 349
E+ + L + ++E++L + +E+ EE
Sbjct: 427 EEMWRQEEKIRELEEMMQDQEEKL--------------------REVEEKMQEE------ 460
Query: 350 TIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLE 409
E K +E Q +K R E I E+EEK E+L +KQE E
Sbjct: 461 -----EEKMQE--------QEEKIQRQEE-----KIQEQEEKTWRQEKL--LKQE----E 496
Query: 410 DEWEREELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMD-KLQGEEEERLKREMLL 468
WE+EE +Q+EK + E+EEK + + + Q ++ + +L +EE+ ++E+ L
Sbjct: 497 KIWEQEEKMWRQEEK--MWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRL 554
Query: 469 AKLNE 473
+L E
Sbjct: 555 QELEE 559
Score = 52.0 bits (123), Expect = 2e-06
Identities = 53/227 (23%), Positives = 110/227 (48%), Gaps = 20/227 (8%)
Query: 111 KINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITA 170
KI E + E+ + K+ E +E K +++ +RQEK + + ++ E + ++R +I
Sbjct: 382 KIQEQEEEMWRQEEKIRE--QEEKRQEKM-WRQEKKMREQDEKIREQEEEMWRQEEKIRE 438
Query: 171 LKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKE-ISEARHLPERDD----LAKKL 225
L+E ++ +EK R E+++++ E ++ + +Q+ +E I E R + +K+
Sbjct: 439 LEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKI 498
Query: 226 VSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEA---HDENKVLQKEV--QR 280
E K+ E ++ E + ++ QRQ E+ R E E K+ ++EV Q
Sbjct: 499 WEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQ--EEKMREQEVRLWQQEEKMQEQEVRLQE 556
Query: 281 LYHKLKEKERELDI-----KNIYSNRLPKSSPNKEKELALRKNAACQ 322
L +L + ++ ++ + S RLP +P + EL ++ + Q
Sbjct: 557 LEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQ 603
Score = 48.9 bits (115), Expect = 2e-05
Identities = 102/481 (21%), Positives = 199/481 (41%), Gaps = 33/481 (6%)
Query: 75 NRKGVRVGFRSQSLNREPLRKDTDLVTKRILSAR-LLKINELQNEVSELQVKLAELLKEN 133
N V+ F+ + +E + + KR++ + L++ E+ + L E L +
Sbjct: 127 NSDEVKSSFKKR---QEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFD 183
Query: 134 KSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTE 193
+++ Y ++ L K DA S ++R+ LKE+ + QEK R E + +
Sbjct: 184 HAVRMGTYIEK--LTKERDAP---SLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQ 238
Query: 194 SELFRTKFSLQKLKEISEARHLP-ERDDLAKKL--VSAELKLDDTERRIKELSKNLELST 250
+ K L++ + + + L E D L K+L VSA+L+ E + L +
Sbjct: 239 LNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEK 298
Query: 251 NSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKE 310
Q + + E++ E K+ ++E + + K E+E I+ + +E
Sbjct: 299 MWRQEEKIQEQEEKM-CEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIRE 357
Query: 311 KELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQS 370
+E +R+ + + + +++ + EE E I E K +E + Q
Sbjct: 358 QEEKIREQEEKMWRQEEKIREQDEKIQE-QEEEMWRQEEKIREQEEKRQEK----MWRQE 412
Query: 371 QKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLER 430
+K E I E+EE+ EE +E+ + ++E RE +K Q+E+ + E+
Sbjct: 413 KKMREQDEK-----IREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQ 467
Query: 431 EEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLL----AKLNEIDRELQDSRNLKY 486
EEK + + + Q +KL +EE+ ++E + K+ E + ++Q+
Sbjct: 468 EEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQ 527
Query: 487 PVLPLLPDFESKLHSPER--SPKTYRFSESSERLFNGHHLQDISFSTPKGEGQNSGNVRS 544
+ + E +L E + R E ERL ++ G G+ SG+ R
Sbjct: 528 RQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELL----GGAGRESGSQRL 583
Query: 545 P 545
P
Sbjct: 584 P 584
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 62.0 bits (149), Expect = 2e-09
Identities = 78/365 (21%), Positives = 163/365 (44%), Gaps = 68/365 (18%)
Query: 110 LKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEIT 169
++ + L E+ + KL ++EN+ L +QE+ + + E+ E + + +I
Sbjct: 262 VEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIR 321
Query: 170 ALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAE 229
+E++ + +EK E+++++ E +++R + +K++E E K+ E
Sbjct: 322 EQEEKMWRQEEKMHEQEEKIREQEDKMWRQE---EKIREQEE------------KIREQE 366
Query: 230 LKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKE 289
K+ E +I+E + ++ RQ R++ + ++ +K+++ K++E+E
Sbjct: 367 EKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQE 426
Query: 290 RELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPE 349
E+ + L + ++E++L + +E+ EE
Sbjct: 427 EEMWRQEEKIRELEEMMQDQEEKL--------------------REVEEKMQEE------ 460
Query: 350 TIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLE 409
E K +E Q +K R E I E+EEK E+L +KQE E
Sbjct: 461 -----EEKMQE--------QEEKIQRQEE-----KIQEQEEKTWRQEKL--LKQE----E 496
Query: 410 DEWEREELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMD-KLQGEEEERLKREMLL 468
WE+EE +Q+EK + E+EEK + + + Q ++ + +L +EE+ ++E+ L
Sbjct: 497 KIWEQEEKMWRQEEK--MWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRL 554
Query: 469 AKLNE 473
+L E
Sbjct: 555 QELEE 559
Score = 52.0 bits (123), Expect = 2e-06
Identities = 53/227 (23%), Positives = 110/227 (48%), Gaps = 20/227 (8%)
Query: 111 KINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITA 170
KI E + E+ + K+ E +E K +++ +RQEK + + ++ E + ++R +I
Sbjct: 382 KIQEQEEEMWRQEEKIRE--QEEKRQEKM-WRQEKKMREQDEKIREQEEEMWRQEEKIRE 438
Query: 171 LKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKE-ISEARHLPERDD----LAKKL 225
L+E ++ +EK R E+++++ E ++ + +Q+ +E I E R + +K+
Sbjct: 439 LEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKI 498
Query: 226 VSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEA---HDENKVLQKEV--QR 280
E K+ E ++ E + ++ QRQ E+ R E E K+ ++EV Q
Sbjct: 499 WEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQ--EEKMREQEVRLWQQEEKMQEQEVRLQE 556
Query: 281 LYHKLKEKERELDI-----KNIYSNRLPKSSPNKEKELALRKNAACQ 322
L +L + ++ ++ + S RLP +P + EL ++ + Q
Sbjct: 557 LEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQ 603
Score = 50.1 bits (118), Expect = 7e-06
Identities = 87/408 (21%), Positives = 168/408 (41%), Gaps = 24/408 (5%)
Query: 147 LNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKL 206
+ K + +S ++R+ LKE+ + QEK R E + + + K L++
Sbjct: 192 IEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERA 251
Query: 207 KEISEARHLP-ERDDLAKKL--VSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKR 263
+ + + L E D L K+L VSA+L+ E + L + Q + + E++
Sbjct: 252 QLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEE 311
Query: 264 AYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQS 323
E K+ ++E + + K E+E I+ + +E+E +R+
Sbjct: 312 KM-CEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMW 370
Query: 324 DFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILN 383
+ + + +++ + EE E I E K +E + Q +K E
Sbjct: 371 RQEEKIREQDEKIQE-QEEEMWRQEEKIREQEEKRQEK----MWRQEKKMREQDEK---- 421
Query: 384 PIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLEREEKPEWETGRYQL 443
I E+EE+ EE +E+ + ++E RE +K Q+E+ + E+EEK + + + Q
Sbjct: 422 -IREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQE 480
Query: 444 GMYPIQNMDKLQGEEEERLKREMLL----AKLNEIDRELQDSRNLKYPVLPLLPDFESKL 499
+KL +EE+ ++E + K+ E + ++Q+ + + E +L
Sbjct: 481 QEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRL 540
Query: 500 HSPER--SPKTYRFSESSERLFNGHHLQDISFSTPKGEGQNSGNVRSP 545
E + R E ERL ++ G G+ SG+ R P
Sbjct: 541 WQQEEKMQEQEVRLQELEERLGKLGQKAELL----GGAGRESGSQRLP 584
>gi|41872583 Rho-associated, coiled-coil containing protein kinase 2
[Homo sapiens]
Length = 1388
Score = 61.6 bits (148), Expect = 2e-09
Identities = 87/420 (20%), Positives = 177/420 (42%), Gaps = 35/420 (8%)
Query: 112 INELQNEVSELQVKLAELLKENKSL-KRLQYRQEKALNKFEDAENEISQLIFRHNNEITA 170
IN+LQ + L+ E LK K L +++ + + +F D E E S + ++
Sbjct: 641 INDLQGRICGLE----EDLKNGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKV 696
Query: 171 LKERLRKSQEKERATEKRVKDTES-----ELFRTKFSLQKLKEISEARHLPERD-----D 220
+++ L + + + +AT+ R+ D E +++ + K++ E R L ++ +
Sbjct: 697 IQQSLEQEEAEHKATKARLADKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLE 756
Query: 221 LAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQR 280
K+ + L ++++I EL K ++ + L + + L+ + Q+
Sbjct: 757 AEKRCSLLDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQ 816
Query: 281 LYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFK 340
+ + LK E++L +N N L + N EK+ NA + + D + + + +
Sbjct: 817 V-NTLKMSEKQLKQEN---NHLMEMKMNLEKQ-----NAELRKERQDADGQMKELQDQLE 867
Query: 341 PEEY--PLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEEL 398
E+Y L + + + EE L +LQ +KQ+ E L +E E+L
Sbjct: 868 AEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKADSEQL 927
Query: 399 --HVVKQEVEKLEDEWEREELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQG 456
+ +++ LE E +EL+ K+ E EK + ++ L
Sbjct: 928 ARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLAN 987
Query: 457 EEEERLKREMLLAKLNEIDRELQDSRNLKYPVLPLLPDFESKLHSPERSPKTYRFSESSE 516
E+EE L KL ++ +L ++ + + FE +L + ER+ KT ++ +E
Sbjct: 988 EKEE------LNNKLKDVQEQLSRLKDEEISAAAIKAQFEKQLLT-ERTLKTQAVNKLAE 1040
Score = 47.0 bits (110), Expect = 6e-05
Identities = 98/408 (24%), Positives = 174/408 (42%), Gaps = 58/408 (14%)
Query: 111 KINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITA 170
K L+N+V+ L+ +L +L K N++ Q EK +N+ + +E + L+ ++
Sbjct: 525 KKRNLENDVNSLKDQLEDLKKRNQN---SQISTEK-VNQLQRQLDETNALLRTESDTAAR 580
Query: 171 LKERLRKSQEKERATEKRVKDTESE---LFRTKFSLQK-LKEISEARHLPERDDLAKKLV 226
L++ +S ++ + E +D + + L K L+K + A RD +
Sbjct: 581 LRKTQAESSKQIQQLESNNRDLQDKNCLLETAKLKLEKEFINLQSALESERRD----RTH 636
Query: 227 SAELKLDDTERRIKELSKNLE-----LSTNSFQRQLLAERKRAYEAHDEN---------K 272
+E+ ++D + RI L ++L+ L+ +++ L ER E N K
Sbjct: 637 GSEI-INDLQGRICGLEEDLKNGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLK 695
Query: 273 VLQK--EVQRLYHKLKEKERELDIKNIY-SNRLPKSSPNKEKELALRKNAACQSDFADLC 329
V+Q+ E + HK K R D IY S KS KE E L + + +L
Sbjct: 696 VIQQSLEQEEAEHK-ATKARLADKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLL 754
Query: 330 TKGVQTME----DFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILN-- 383
+ + D K + + E + + E+ +LTL ++ + Q R L
Sbjct: 755 LEAEKRCSLLDCDLKQSQQKIN-ELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQ 813
Query: 384 ----PIMEREEKFVTDEELHV--VKQEVEKLEDEW--EREELDKKQKEKASLLEREEKPE 435
++ EK + E H+ +K +EK E ER++ D + KE LE E+
Sbjct: 814 TQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQ--- 870
Query: 436 WETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQDSRN 483
Y +Y Q + +L+ E EE+ K L +L + +ELQD R+
Sbjct: 871 -----YFSTLYKTQ-VRELKEECEEKTK---LGKELQQKKQELQDERD 909
>gi|58530840 desmoplakin isoform I [Homo sapiens]
Length = 2871
Score = 61.2 bits (147), Expect = 3e-09
Identities = 83/387 (21%), Positives = 165/387 (42%), Gaps = 35/387 (9%)
Query: 86 QSLNREPLRKDTDLVTKRILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEK 145
+ LNR D ++ L L ++ + E +K+ L ++ + ++ R E
Sbjct: 1575 EELNRLKRTASEDSCKRKKLEEEL---EGMRRSLKEQAIKITNLTQQLEQASIVKKRSED 1631
Query: 146 ALNKFEDA-------ENEISQLIFRHNNEITALKERLRKSQEKERAT-------EKRVKD 191
L + D + + + R ++E+ AL+ +L + QE + +K ++D
Sbjct: 1632 DLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQLLQEQESVKQAHLRNEHFQKAIED 1691
Query: 192 TESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTN 251
L +K +++L+ ++E E L ++L + L+ DD R E + +
Sbjct: 1692 KSRSLNESKIEIERLQSLTE-NLTKEHLMLEEELRNLRLEYDDLRRGRSEADSDKNATIL 1750
Query: 252 SFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERE-LDIKN-IYSNRLPKSSPNK 309
+ QL R E LQ+E + L ++++ +++ L+ N I ++ + +
Sbjct: 1751 ELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQ 1810
Query: 310 EKELALRKNAACQSDFADLCTKGVQTMED-FKPEEYPLTPETIMCYENKWEEPGHLTLDL 368
E+E L K + D A L Q +ED + L ET + + E+ + DL
Sbjct: 1811 ERESLLVKIKVLEQDKARL-----QRLEDELNRAKSTLEAETRVKQRLECEKQ-QIQNDL 1864
Query: 369 QSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQKEKASLL 428
K + + I EK ++ E + ++ E+E+L+ E +R E ++K + S
Sbjct: 1865 NQWKTQYSRKEEAIRKIESEREK--SEREKNSLRSEIERLQAEIKRIEERCRRKLEDSTR 1922
Query: 429 EREEKPEWETGRYQLGMYPIQNMDKLQ 455
E + + E E RYQ + +DKL+
Sbjct: 1923 ETQSQLETERSRYQ------REIDKLR 1943
Score = 55.8 bits (133), Expect = 1e-07
Identities = 108/492 (21%), Positives = 201/492 (40%), Gaps = 96/492 (19%)
Query: 78 GVRVGFRSQSLNREPLRKDTDLVT------KRILSARLLKINELQNEVSELQVKLAE--- 128
G V R Q L E LR+ T + T K+ L I + E+ L+ + +
Sbjct: 1437 GSEVSQRKQQLEVE-LRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQLIDKETN 1495
Query: 129 ----LLKENKSLKRLQYRQEKA-------LNKFEDAENEISQL----------------- 160
L EN L+R+QY +KA +NK + E E+++L
Sbjct: 1496 DRKCLEDENARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQERTVKDQD 1555
Query: 161 IFRHNNEITALKERLRKSQEK---------ERATEKRVKDTESELFRTKFSLQKLK---- 207
I R N + L+ + +K +E+ E + +++ + E E R Q +K
Sbjct: 1556 ITRFQNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNL 1615
Query: 208 --EISEARHLPER--DDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKR 263
++ +A + +R DDL ++ + L + +R +EL + L + +RQLL E++
Sbjct: 1616 TQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEEL-RRLSSEVEALRRQLLQEQES 1674
Query: 264 AYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQS 323
+AH N+ QK ++ L E + E++ + L K E+EL +N +
Sbjct: 1675 VKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEEL---RNLRLEY 1731
Query: 324 DFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQD--------- 374
D DL +G + K + N+ E L DLQ ++++
Sbjct: 1732 D--DL-RRGRSEADSDKNATILELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ 1788
Query: 375 ----------RHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWERE----ELDKK 420
+ + + ERE V + L K +++LEDE R E + +
Sbjct: 1789 KQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKSTLEAETR 1848
Query: 421 QKEKASLLERE---EKPEWET--GRYQLGMYPIQNMDKLQGEEEERLKREM--LLAKLNE 473
K++ +++ + +W+T R + + I++ + E+ L+ E+ L A++
Sbjct: 1849 VKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR 1908
Query: 474 ID----RELQDS 481
I+ R+L+DS
Sbjct: 1909 IEERCRRKLEDS 1920
Score = 45.4 bits (106), Expect = 2e-04
Identities = 47/194 (24%), Positives = 90/194 (46%), Gaps = 27/194 (13%)
Query: 90 REPLRKDTDLVTKRILSARLLKINELQNEVSE-------LQVKLAELLKENKSLKRLQYR 142
RE LR++ + K+ L A +I E +N+ ++ L VK+ L ++ L+RL+
Sbjct: 1777 RENLRQEIEKFQKQALEASN-RIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDE 1835
Query: 143 QEKALNKFEDAENEISQLIF----RHNNEITALKERLRKSQEKERATEKRVKDTESELFR 198
+A + E AE + Q + + N++ K + + +E R E + +E E
Sbjct: 1836 LNRAKSTLE-AETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNS 1894
Query: 199 TKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLL 258
+ +++L+ +E + + ER KL+D+ R E LE + +QR++
Sbjct: 1895 LRSEIERLQ--AEIKRIEER---------CRRKLEDSTR---ETQSQLETERSRYQREID 1940
Query: 259 AERKRAYEAHDENK 272
R+R Y +H E +
Sbjct: 1941 KLRQRPYGSHRETQ 1954
Score = 44.7 bits (104), Expect = 3e-04
Identities = 88/415 (21%), Positives = 175/415 (42%), Gaps = 66/415 (15%)
Query: 132 ENKSLKRLQYR-QEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVK 190
+NK ++RL+ QE+A ++E ENE+S++ ++ EI +LK +
Sbjct: 1323 KNKEIERLKAEFQEEAKRRWE-YENELSKVRNNYDEEIISLKNQF--------------- 1366
Query: 191 DTESELFRTKFSLQKL---KEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLE 247
E+E+ TK ++ +L KE + + + D+L ++ S ++ + + + ++NL
Sbjct: 1367 --ETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQTTENLR 1424
Query: 248 LSTNSFQRQL-----LAERKRAYEA--HDENKVLQKEVQRLYHKLKEKERELDIKNIYSN 300
Q+Q +++RK+ E ++ +E R L + + + KN
Sbjct: 1425 RVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIE 1484
Query: 301 RLPK--SSPNKEKELALRKNAACQS---DFADLCTKGVQTMEDFKPEEYPLTPETIMCYE 355
RL + +++ +NA Q D + +T+ K +E LT
Sbjct: 1485 RLKQLIDKETNDRKCLEDENARLQRVQYDLQKANSSATETINKLKVQEQELT-------- 1536
Query: 356 NKWEEPGHLTLDLQSQKQDR----HGEAGILNPIMERE-EKFVTDEELHVVKQEVEKLED 410
L +D + Q+R N + E + +K +EEL+ +K+ ED
Sbjct: 1537 -------RLRIDYERVSQERTVKDQDITRFQNSLKELQLQKQKVEEELNRLKRTAS--ED 1587
Query: 411 EWEREELDKK-QKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLA 469
+R++L+++ + + SL E+ K T + + ++ K + E++ R +R++L
Sbjct: 1588 SCKRKKLEEELEGMRRSLKEQAIKITNLTQQLEQA-----SIVKKRSEDDLRQQRDVLDG 1642
Query: 470 KLNEIDRELQDSRNLKYPV----LPLLPDFESKLHSPERSPKTYRFSESSERLFN 520
L E R ++ R L V LL + ES + R+ + E R N
Sbjct: 1643 HLREKQRTQEELRRLSSEVEALRRQLLQEQESVKQAHLRNEHFQKAIEDKSRSLN 1697
Score = 40.0 bits (92), Expect = 0.007
Identities = 90/425 (21%), Positives = 166/425 (39%), Gaps = 53/425 (12%)
Query: 111 KINELQNEVSELQVKLAELLKEN---------KSLKRLQYR--------QEKALNKFEDA 153
+ ++ +N+ +LQ K + KEN K++K +Y QE+ K E
Sbjct: 1131 RFDQQKNDYDQLQ-KARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQEEGTRKRE-Y 1188
Query: 154 ENEISQLIFRHNNEITALKER------LRKSQEKERATEKR--VKDTESELFRTKFSLQK 205
ENE++++ +N E++ L+ + + K+ KE + +K K+ ++L R +
Sbjct: 1189 ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD 1248
Query: 206 LK-----------EISEARHLPERDDLAKKLVSAEL--KLDDTERRIKELSKNLELSTNS 252
LK + +E R E + L +K +E+ K E +K++ +
Sbjct: 1249 LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNAR 1308
Query: 253 FQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELD-IKNIYSNRLPKSSPNKEK 311
++ L K + + E + L+ E Q + E E EL ++N Y + E
Sbjct: 1309 HKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFET 1368
Query: 312 ELALRKNAACQSDF-ADLCTKGVQTMEDFKPEEYPLTPETIMCYEN----KWEEPGHLTL 366
E+ + K Q + T G + D E E I +N E +
Sbjct: 1369 EINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEE 1428
Query: 367 DLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWER-EELDKKQKEKA 425
D+Q QK E +E E + VT + + L+D + ++ +K+ +
Sbjct: 1429 DIQQQKA-TGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLK 1487
Query: 426 SLLEREEKP----EWETGRYQLGMYPIQNMDKLQGEEEERLK-REMLLAKLNEIDRELQD 480
L+++E E E R Q Y +Q + E +LK +E L +L +
Sbjct: 1488 QLIDKETNDRKCLEDENARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQ 1547
Query: 481 SRNLK 485
R +K
Sbjct: 1548 ERTVK 1552
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 61.2 bits (147), Expect = 3e-09
Identities = 91/425 (21%), Positives = 187/425 (44%), Gaps = 51/425 (12%)
Query: 111 KINELQNEV-------SELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFR 163
K+++LQNEV +E + K +L K+ SL ++ L + + +S + +
Sbjct: 1281 KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQ 1340
Query: 164 HNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEA------RHLPE 217
E +L+++L + E ++ E+ + +L +K LQ EA R E
Sbjct: 1341 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1400
Query: 218 RDDLAKKL---VSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVL 274
++L ++ +A KL+ T+ R+++ +L + ++ QRQL++ ++ D+
Sbjct: 1401 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN-QRQLVSNLEKKQRKFDQLLAE 1459
Query: 275 QKEVQRLY----HKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCT 330
+K + Y + + + RE + K + R + + ++EL R N +++ DL +
Sbjct: 1460 EKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELE-RTNKMLKAEMEDLVS 1518
Query: 331 ------KGVQTMEDFKP------EEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGE 378
K V +E K EE E + E++ + L L+ Q G+
Sbjct: 1519 SKDDVGKNVHELEKSKRALETQMEEMKTQLEEL---EDELQATEDAKLRLEVNMQALKGQ 1575
Query: 379 AGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLEREEKPEWET 438
ER+ + DE+ ++++++ E+E E L+ ++K++A ++K E +
Sbjct: 1576 -------FERDLQ-ARDEQNEEKRRQLQRQLHEYETE-LEDERKQRALAAAAKKKLEGDL 1626
Query: 439 GRYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQDSRNLKYPVLPLLPDFESK 498
+L Q ++G EE + L A++ + REL+D+R + + + E K
Sbjct: 1627 KDLEL-----QADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKK 1681
Query: 499 LHSPE 503
S E
Sbjct: 1682 AKSLE 1686
Score = 54.3 bits (129), Expect = 4e-07
Identities = 95/408 (23%), Positives = 166/408 (40%), Gaps = 51/408 (12%)
Query: 114 ELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKE 173
+L + + + Q K +LL E K++ +Y E+ + E E E L AL+E
Sbjct: 1441 QLVSNLEKKQRKFDQLLAEEKNISS-KYADERDRAEAEAREKETKALSLAR-----ALEE 1494
Query: 174 RLRKSQEKERATEKRVKDTESELFRTKFSLQK-LKEISEARHLPER--DDLAKKLVSAEL 230
L +E ER T K +K +L +K + K + E+ +++ E +++ +L E
Sbjct: 1495 ALEAKEELER-TNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED 1553
Query: 231 KLDDTERRIKELSKNLELSTNSFQRQLLA-----ERKRAY---EAHDENKVLQKE-VQRL 281
+L TE L N++ F+R L A E KR + H+ L+ E QR
Sbjct: 1554 ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRA 1613
Query: 282 YHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKP 341
+K+ E D+K++ L S K +E A+++ Q+ D + +ED +
Sbjct: 1614 LAAAAKKKLEGDLKDL---ELQADSAIKGREEAIKQLRKLQAQMKDF----QRELEDARA 1666
Query: 342 EEYPLTPETIMCYENKWEEPGHLTLDLQSQKQD-RHGEAGILNPIMEREEKFVTDEELHV 400
E + ++ L DL ++D E +E+EE EEL
Sbjct: 1667 SR----DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEE---LAEELAS 1719
Query: 401 VKQEVEKLEDEWEREELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEE 460
L+DE K++ +A + + EE+ E E G + ++ + +
Sbjct: 1720 SLSGRNALQDE--------KRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSN 1771
Query: 461 RLKREMLLAKLNEIDRELQDSRNLKYPVLPLLPDFESKLHSPERSPKT 508
L E A+ NE R+ + +N + SKLH E + K+
Sbjct: 1772 ELATERSTAQKNESARQQLERQN---------KELRSKLHEMEGAVKS 1810
Score = 52.8 bits (125), Expect = 1e-06
Identities = 90/414 (21%), Positives = 167/414 (40%), Gaps = 57/414 (13%)
Query: 102 KRILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLI 161
K +L +L EL E E++V+LA +E L+ + + E L + ED ++
Sbjct: 889 KNLLQEQLQAETELYAEAEEMRVRLAAKKQE---LEEILHEMEARLEEEEDRGQQLQAER 945
Query: 162 FRHNNEITALKERL-------RKSQEKERATEKRVKDTESELF---RTKFSLQKLKEISE 211
+ ++ L+E+L +K Q ++ E ++K E E+ L K +++ E
Sbjct: 946 KKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLE 1005
Query: 212 AR------HLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAY 265
R +L E ++ AK L + K E I EL L+ S RQ L + KR
Sbjct: 1006 ERISDLTTNLAEEEEKAKNLTKLKNK---HESMISELEVRLKKEEKS--RQELEKLKRKL 1060
Query: 266 EA-----HDENKVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAA 320
E H++ LQ ++ L +L +KE EL RL K AL+K
Sbjct: 1061 EGDASDFHEQIADLQAQIAELKMQLAKKEEELQAA---LARLDDEIAQKNN--ALKKIRE 1115
Query: 321 CQSDFADLCTKGVQTMEDFKPEEYPLTP---------ETIMCYENKWEEPGHLTLDLQSQ 371
+ +DL ED E E + + + E+ T Q
Sbjct: 1116 LEGHISDL-------QEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQEL 1168
Query: 372 KQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLERE 431
+ R E +L ++ E + + + ++ + +E+ E+L++ ++ KA+L + +
Sbjct: 1169 RAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEE--LTEQLEQFKRAKANLDKNK 1226
Query: 432 EKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQDSRNLK 485
+ E E + + Q ++E K++ L A++ E+ + D +
Sbjct: 1227 QTLEKENADLAGELRVLG-----QAKQEVEHKKKKLEAQVQELQSKCSDGERAR 1275
Score = 52.0 bits (123), Expect = 2e-06
Identities = 82/406 (20%), Positives = 167/406 (41%), Gaps = 49/406 (12%)
Query: 94 RKDTDLVTKRILSARLLKINELQN-EVSELQVKLAELLKENKSLKRLQYRQE---KALNK 149
++ L +++ +L+N + L K+ LL+ + + +Q +++ K +
Sbjct: 808 KRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKER 867
Query: 150 FEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEI 209
+ AENE+ +L +H +++T K L++ + E ++ L K L+++
Sbjct: 868 QQKAENELKELEQKH-SQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHE 926
Query: 210 SEARHLPERD----------DLAKKLVSAELKLDDTE--RRIKELSK-NLELSTNSFQRQ 256
EAR E D +A++++ E +L++ E R+ +L K E + +
Sbjct: 927 MEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDE 986
Query: 257 LLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALR 316
+L + + E K+L++ + L L E+E + KN+ + S E E+ L+
Sbjct: 987 ILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEK--AKNLTKLKNKHESMISELEVRLK 1044
Query: 317 KNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRH 376
K + + L K DF + L + L +Q K++
Sbjct: 1045 KEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI-------------AELKMQLAKKEEE 1091
Query: 377 GEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEW--EREELDKKQKEKASLLEREE-- 432
+A + E +K +++ ++ + L+++ ER +K +K+K L E E
Sbjct: 1092 LQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEAL 1151
Query: 433 KPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNE-IDRE 477
K E E +D ++E R KRE + L + +D E
Sbjct: 1152 KTELE-----------DTLDSTATQQELRAKREQEVTVLKKALDEE 1186
Score = 41.6 bits (96), Expect = 0.003
Identities = 88/408 (21%), Positives = 174/408 (42%), Gaps = 61/408 (14%)
Query: 101 TKRILSARLLKIN-ELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQ 159
+KR L ++ ++ +L+ ELQ L+ +++ L+ + E+ L ++ E +
Sbjct: 1533 SKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRR 1592
Query: 160 LIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKE--ISEARHLP- 216
+ R +E E RK + A +K+++ +L S K +E I + R L
Sbjct: 1593 QLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQA 1652
Query: 217 ERDDLAKKLVSAELKLDD---TERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENK- 272
+ D ++L A D+ T + ++ +K+LE Q L A + +A E +
Sbjct: 1653 QMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEE 1712
Query: 273 -------------VLQKEVQRLYHKLKEKERELDIKN----IYSNRLPKSSPNKEK---E 312
LQ E +RL ++ + E EL+ + S+R+ K++ E+ E
Sbjct: 1713 LAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 1772
Query: 313 LALRKNAACQSDFA---------DLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGH 363
LA ++ A +++ A +L +K + ME ++ TI E K +
Sbjct: 1773 LATERSTAQKNESARQQLERQNKELRSK-LHEMEGAVKSKFK---STIAALEAKIAQ--- 1825
Query: 364 LTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQKE 423
L+ Q +++ R +A + + ++++K +K+ + ++EDE + E K+Q E
Sbjct: 1826 --LEEQVEQEAREKQAATKS-LKQKDKK---------LKEILLQVEDERKMAEQYKEQAE 1873
Query: 424 KAS-----LLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREM 466
K + L + E+ E E+ R +Q E E + RE+
Sbjct: 1874 KGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREV 1921
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.128 0.349
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,189,817
Number of Sequences: 37866
Number of extensions: 1381923
Number of successful extensions: 13352
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 255
Number of HSP's successfully gapped in prelim test: 1013
Number of HSP's that attempted gapping in prelim test: 7085
Number of HSP's gapped (non-prelim): 4218
length of query: 697
length of database: 18,247,518
effective HSP length: 109
effective length of query: 588
effective length of database: 14,120,124
effective search space: 8302632912
effective search space used: 8302632912
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.