Guide to the Human Genome
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Search of human proteins with 16936540

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|16936540 crystallin, beta A2 [Homo sapiens]
         (197 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|16936542 crystallin, beta A2 [Homo sapiens]                        421   e-118
gi|16936540 crystallin, beta A2 [Homo sapiens]                        421   e-118
gi|7019357 crystallin, beta A2 [Homo sapiens]                         421   e-118
gi|12056461 crystallin, beta A3 [Homo sapiens]                        235   2e-62
gi|4503059 crystallin, beta A4 [Homo sapiens]                         221   3e-58
gi|4503061 crystallin, beta B1 [Homo sapiens]                         166   9e-42
gi|4758074 crystallin, beta B3 [Homo sapiens]                         144   5e-35
gi|4503063 crystallin, beta B2 [Homo sapiens]                         134   4e-32
gi|21389517 gammaN-crystallin [Homo sapiens]                          109   2e-24
gi|8922120 crystallin, gamma S [Homo sapiens]                         103   7e-23
gi|148491057 crystallin, gamma A [Homo sapiens]                       103   9e-23
gi|10518338 crystallin, gamma C [Homo sapiens]                         99   3e-21
gi|148491074 crystallin, gamma B [Homo sapiens]                        94   7e-20
gi|62988361 absent in melanoma 1 [Homo sapiens]                        90   1e-18
gi|90403579 beta-gamma crystallin domain containing 3 [Homo sapi...    89   2e-18
gi|13377002 crystallin, gamma D [Homo sapiens]                         89   3e-18
gi|89886227 absent in melanoma 1-like [Homo sapiens]                   88   5e-18
gi|87298939 hypothetical protein LOC131831 [Homo sapiens]              30   1.3  
gi|134244285 Notch homolog 3 [Homo sapiens]                            29   2.3  
gi|134031945 SCO-spondin [Homo sapiens]                                28   5.0  
gi|4557529 post-synaptic density protein 95 isoform 1 [Homo sapi...    27   8.6  
gi|192447426 post-synaptic density protein 95 isoform 2 [Homo sa...    27   8.6  
gi|218156340 chapsyn-110 isoform 3 [Homo sapiens]                      27   8.6  
gi|218156270 chapsyn-110 isoform 4 [Homo sapiens]                      27   8.6  
gi|45120115 hypothetical protein LOC56905 [Homo sapiens]               27   8.6  
gi|95147342 chromodomain helicase DNA binding protein 9 [Homo sa...    27   8.6  

>gi|16936542 crystallin, beta A2 [Homo sapiens]
          Length = 197

 Score =  421 bits (1082), Expect = e-118
 Identities = 197/197 (100%), Positives = 197/197 (100%)

Query: 1   MSSAPAPGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEY 60
           MSSAPAPGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEY
Sbjct: 1   MSSAPAPGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEY 60

Query: 61  PDFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCK 120
           PDFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCK
Sbjct: 61  PDFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCK 120

Query: 121 FDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGEL 180
           FDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGEL
Sbjct: 121 FDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGEL 180

Query: 181 GTQAHTGQLQSIRRVQH 197
           GTQAHTGQLQSIRRVQH
Sbjct: 181 GTQAHTGQLQSIRRVQH 197


>gi|16936540 crystallin, beta A2 [Homo sapiens]
          Length = 197

 Score =  421 bits (1082), Expect = e-118
 Identities = 197/197 (100%), Positives = 197/197 (100%)

Query: 1   MSSAPAPGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEY 60
           MSSAPAPGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEY
Sbjct: 1   MSSAPAPGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEY 60

Query: 61  PDFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCK 120
           PDFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCK
Sbjct: 61  PDFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCK 120

Query: 121 FDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGEL 180
           FDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGEL
Sbjct: 121 FDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGEL 180

Query: 181 GTQAHTGQLQSIRRVQH 197
           GTQAHTGQLQSIRRVQH
Sbjct: 181 GTQAHTGQLQSIRRVQH 197


>gi|7019357 crystallin, beta A2 [Homo sapiens]
          Length = 197

 Score =  421 bits (1082), Expect = e-118
 Identities = 197/197 (100%), Positives = 197/197 (100%)

Query: 1   MSSAPAPGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEY 60
           MSSAPAPGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEY
Sbjct: 1   MSSAPAPGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEY 60

Query: 61  PDFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCK 120
           PDFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCK
Sbjct: 61  PDFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCK 120

Query: 121 FDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGEL 180
           FDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGEL
Sbjct: 121 FDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGEL 180

Query: 181 GTQAHTGQLQSIRRVQH 197
           GTQAHTGQLQSIRRVQH
Sbjct: 181 GTQAHTGQLQSIRRVQH 197


>gi|12056461 crystallin, beta A3 [Homo sapiens]
          Length = 215

 Score =  235 bits (600), Expect = 2e-62
 Identities = 104/193 (53%), Positives = 145/193 (75%), Gaps = 2/193 (1%)

Query: 5   PAPGP-APASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDF 63
           P PG   P  +T++D+E+FQG+R    S C NV ER     VRS+KVE+G W+ +E+  F
Sbjct: 23  PTPGSLGPWKITIYDQENFQGKRMEFTSSCPNVSERS-FDNVRSLKVESGAWIGYEHTSF 81

Query: 64  QGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDL 123
            GQQFILE+G+YPRW AWSGS++++  +L+SFRP+  ANH +S++T+FE +NF G ++++
Sbjct: 82  CGQQFILERGEYPRWDAWSGSNAYHIERLMSFRPICSANHKESKMTIFEKENFIGRQWEI 141

Query: 124 VDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGELGTQ 183
            DDYPSL +MGW + +VGS+K+ SGAWV YQYPGYRGYQY+LE D H G++  + E G+ 
Sbjct: 142 SDDYPSLQAMGWFNNEVGSMKIQSGAWVCYQYPGYRGYQYILECDHHGGDYKHWREWGSH 201

Query: 184 AHTGQLQSIRRVQ 196
           A T Q+QSIRR+Q
Sbjct: 202 AQTSQIQSIRRIQ 214


>gi|4503059 crystallin, beta A4 [Homo sapiens]
          Length = 196

 Score =  221 bits (563), Expect = 3e-58
 Identities = 102/186 (54%), Positives = 134/186 (72%), Gaps = 1/186 (0%)

Query: 11  PASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFIL 70
           P  + +WDE+ FQGRR    ++C +V E G    VRS+KV +G WV FE+  FQGQQ+IL
Sbjct: 11  PWKMVVWDEDGFQGRRHEFTAECPSVLELG-FETVRSLKVLSGAWVGFEHAGFQGQQYIL 69

Query: 71  EKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYPSL 130
           E+G+YP W AW G++++ + +L SFRP  CANH DSR+T+FE +NF G K +L DDYPSL
Sbjct: 70  ERGEYPSWDAWGGNTAYPAERLTSFRPAACANHRDSRLTIFEQENFLGKKGELSDDYPSL 129

Query: 131 PSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGELGTQAHTGQLQ 190
            +MGW   +VGS  V SGAWV  Q+PGYRG+QYVLE D HSG++  + E G+ A T Q+Q
Sbjct: 130 QAMGWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECDHHSGDYKHFREWGSHAPTFQVQ 189

Query: 191 SIRRVQ 196
           SIRR+Q
Sbjct: 190 SIRRIQ 195


>gi|4503061 crystallin, beta B1 [Homo sapiens]
          Length = 252

 Score =  166 bits (421), Expect = 9e-42
 Identities = 91/189 (48%), Positives = 129/189 (68%), Gaps = 12/189 (6%)

Query: 9   PAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQF 68
           P    L +++ E+FQGRR     +C+N+ +RG   RVRS+ V  G WVAFE  +F+G+ F
Sbjct: 56  PGNYRLVVFELENFQGRRAEFSGECSNLADRG-FDRVRSIIVSAGPWVAFEQSNFRGEMF 114

Query: 69  ILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLV-DDY 127
           ILEKG+YPRW+ W  SSS+ S++L+SFRP+   +  + +++LFEG NF+G   ++  DD 
Sbjct: 115 ILEKGEYPRWNTW--SSSYRSDRLMSFRPIK-MDAQEHKISLFEGANFKGNTIEIQGDDA 171

Query: 128 PSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGELGTQAHTG 187
           PSL   G++ + VGS+KVSSG WV YQYPGYRGYQY+LE     G+F  + E G  A   
Sbjct: 172 PSLWVYGFSDR-VGSVKVSSGTWVGYQYPGYRGYQYLLE----PGDFRHWNEWG--AFQP 224

Query: 188 QLQSIRRVQ 196
           Q+QS+RR++
Sbjct: 225 QMQSLRRLR 233


>gi|4758074 crystallin, beta B3 [Homo sapiens]
          Length = 211

 Score =  144 bits (363), Expect = 5e-35
 Identities = 82/182 (45%), Positives = 120/182 (65%), Gaps = 12/182 (6%)

Query: 16  LWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKGDY 75
           L++ E+FQG+RC L ++C ++ +   L +V S++VE+G W+AFE   F+G+QF+LEKGDY
Sbjct: 28  LYELENFQGKRCELSAECPSLTD-SLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKGDY 86

Query: 76  PRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLV-DDYPSLPSMG 134
           PRW AW  S+S +S+ LLS RP L  +    ++ LFE   F G K ++V DD PSL + G
Sbjct: 87  PRWDAW--SNSRDSDSLLSLRP-LNIDSPHHKLHLFENPAFSGRKMEIVDDDVPSLWAHG 143

Query: 135 WASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGELGTQAHTGQLQSIRR 194
           +  + V S++  +G WV Y++PGYRG QYV ER    GE+  + E    A   QLQS+RR
Sbjct: 144 FQDR-VASVRAINGTWVGYEFPGYRGRQYVFER----GEYRHWNE--WDASQPQLQSVRR 196

Query: 195 VQ 196
           ++
Sbjct: 197 IR 198



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 29/87 (33%), Positives = 49/87 (56%), Gaps = 6/87 (6%)

Query: 107 RVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLE 166
           +V L+E +NFQG + +L  + PSL       + VGS++V SG W+A++   +RG Q+VLE
Sbjct: 25  KVILYELENFQGKRCELSAECPSLTDS--LLEKVGSIQVESGPWLAFESRAFRGEQFVLE 82

Query: 167 RDRHSGEFCTYGELGTQAHTGQLQSIR 193
           +    G++  +        +  L S+R
Sbjct: 83  K----GDYPRWDAWSNSRDSDSLLSLR 105


>gi|4503063 crystallin, beta B2 [Homo sapiens]
          Length = 205

 Score =  134 bits (338), Expect = 4e-32
 Identities = 74/196 (37%), Positives = 117/196 (59%), Gaps = 12/196 (6%)

Query: 2   SSAPAPGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYP 61
           + A  P      + ++++E+FQG    L   C N+ E G + +  SV V+ G WV +E  
Sbjct: 7   TQAGKPQSLNPKIIIFEQENFQGHSHELNGPCPNLKETG-VEKAGSVLVQAGPWVGYEQA 65

Query: 62  DFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKF 121
           + +G+QF+ EKG+YPRW +W  +SS  ++ L S RP+   +  + ++ L+E  NF G K 
Sbjct: 66  NCKGEQFVFEKGEYPRWDSW--TSSRRTDSLSSLRPIK-VDSQEHKIILYENPNFTGKKM 122

Query: 122 DLV-DDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGEL 180
           +++ DD PS  + G+  K V S++V SG WV YQYPGYRG QY+LE+    G++    + 
Sbjct: 123 EIIDDDVPSFHAHGYQEK-VSSVRVQSGTWVGYQYPGYRGLQYLLEK----GDYKDSSDF 177

Query: 181 GTQAHTGQLQSIRRVQ 196
           G  A   Q+QS+RR++
Sbjct: 178 G--APHPQVQSVRRIR 191


>gi|21389517 gammaN-crystallin [Homo sapiens]
          Length = 182

 Score =  109 bits (272), Expect = 2e-24
 Identities = 58/140 (41%), Positives = 82/140 (58%), Gaps = 9/140 (6%)

Query: 14  LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73
           +TL++ + F G++  +  DC N  +RG + RV S+ VE+G WV F +PDF+GQQFILE G
Sbjct: 8   ITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILEHG 67

Query: 74  DYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDS-RVTLFEGDNFQGCKFDLVDDYPSLPS 132
           DYP +  W+  S H    + S RPV    H +  R+ +FEG NF G   + ++D P L S
Sbjct: 68  DYPDFFRWNSHSDH----MGSCRPV--GMHGEHFRLEIFEGCNFTGQCLEFLEDSPFLQS 121

Query: 133 MGWASKDVGSLKV--SSGAW 150
            GW    V ++KV     AW
Sbjct: 122 RGWVKNCVNTIKVYGDGAAW 141



 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 23/60 (38%), Positives = 39/60 (65%), Gaps = 1/60 (1%)

Query: 107 RVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLE 166
           ++TL+EG +F G K ++  D  +    G+ ++ V S+ V SGAWV + +P +RG Q++LE
Sbjct: 7   KITLYEGKHFTGQKLEVFGDCDNFQDRGFMNR-VNSIHVESGAWVCFNHPDFRGQQFILE 65


>gi|8922120 crystallin, gamma S [Homo sapiens]
          Length = 178

 Score =  103 bits (258), Expect = 7e-23
 Identities = 52/157 (33%), Positives = 88/157 (56%), Gaps = 7/157 (4%)

Query: 14  LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73
           +T +++++FQGRR     DCA+      L R  S+KVE G W  +E P+F G  +IL +G
Sbjct: 8   ITFYEDKNFQGRRYDCDCDCADF--HTYLSRCNSIKVEGGTWAVYERPNFAGYMYILPQG 65

Query: 74  DYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYPSLPSM 133
           +YP +  W G     +++L S R V   +    ++ +FE  +F G  ++  +D PS+   
Sbjct: 66  EYPEYQRWMGL----NDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIMEQ 121

Query: 134 GWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRH 170
            +  +++ S KV  G W+ Y+ P YRG QY+L++  +
Sbjct: 122 -FHMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEY 157



 Score = 56.6 bits (135), Expect = 1e-08
 Identities = 22/79 (27%), Positives = 45/79 (56%)

Query: 7   PGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQ 66
           P      + ++++ DF G+      DC ++ E+  +  + S KV  GVW+ +E P+++G+
Sbjct: 89  PSGGQYKIQIFEKGDFSGQMYETTEDCPSIMEQFHMREIHSCKVLEGVWIFYELPNYRGR 148

Query: 67  QFILEKGDYPRWSAWSGSS 85
           Q++L+K +Y +   W  +S
Sbjct: 149 QYLLDKKEYRKPIDWGAAS 167



 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 23/72 (31%), Positives = 38/72 (52%), Gaps = 7/72 (9%)

Query: 106 SRVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVL 165
           +++T +E  NFQG ++D   D     +  + S+   S+KV  G W  Y+ P + GY Y+L
Sbjct: 6   TKITFYEDKNFQGRRYDCDCDCADFHT--YLSR-CNSIKVEGGTWAVYERPNFAGYMYIL 62

Query: 166 ERDRHSGEFCTY 177
            +    GE+  Y
Sbjct: 63  PQ----GEYPEY 70


>gi|148491057 crystallin, gamma A [Homo sapiens]
          Length = 174

 Score =  103 bits (257), Expect = 9e-23
 Identities = 58/180 (32%), Positives = 99/180 (55%), Gaps = 14/180 (7%)

Query: 14  LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73
           +T +++ DFQGR    +SDC N+  R    R  S++V++G W+ +E P++QG Q+ L +G
Sbjct: 4   ITFYEDRDFQGRCYNCISDCPNL--RVYFSRCNSIRVDSGCWMLYERPNYQGHQYFLRRG 61

Query: 74  DYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYPSLPSM 133
            YP +  W G     S+ + S R  +  + +  ++ L+E D+++G   +L DD   +P +
Sbjct: 62  KYPDYQHWMGL----SDSVQSCR--IIPHTSSHKLRLYERDDYRGLMSELTDDCACVPEL 115

Query: 134 GWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGEL-GTQAHTGQLQSI 192
            +   ++ SL V  G WV Y+ P YRG QY+L      G++  Y +  G  A  G L+ +
Sbjct: 116 -FRLPEIYSLHVLEGCWVLYEMPNYRGRQYLL----RPGDYRRYHDWGGADAKVGSLRRV 170



 Score = 66.2 bits (160), Expect = 2e-11
 Identities = 29/80 (36%), Positives = 47/80 (58%)

Query: 7   PGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQ 66
           P  +   L L++ +D++G    L  DCA V E   LP + S+ V  G WV +E P+++G+
Sbjct: 83  PHTSSHKLRLYERDDYRGLMSELTDDCACVPELFRLPEIYSLHVLEGCWVLYEMPNYRGR 142

Query: 67  QFILEKGDYPRWSAWSGSSS 86
           Q++L  GDY R+  W G+ +
Sbjct: 143 QYLLRPGDYRRYHDWGGADA 162



 Score = 47.4 bits (111), Expect = 8e-06
 Identities = 21/64 (32%), Positives = 37/64 (57%), Gaps = 3/64 (4%)

Query: 107 RVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLE 166
           ++T +E  +FQG  ++ + D P+L           S++V SG W+ Y+ P Y+G+QY L 
Sbjct: 3   KITFYEDRDFQGRCYNCISDCPNLRVY---FSRCNSIRVDSGCWMLYERPNYQGHQYFLR 59

Query: 167 RDRH 170
           R ++
Sbjct: 60  RGKY 63


>gi|10518338 crystallin, gamma C [Homo sapiens]
          Length = 174

 Score = 98.6 bits (244), Expect = 3e-21
 Identities = 52/152 (34%), Positives = 85/152 (55%), Gaps = 9/152 (5%)

Query: 14  LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73
           +T +++  FQGR     +DC N+  +    R  S++VE+G W+ +E P++QGQQ++L +G
Sbjct: 4   ITFYEDRAFQGRSYETTTDCPNL--QPYFSRCNSIRVESGCWMLYERPNYQGQQYLLRRG 61

Query: 74  DYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYPSLPSM 133
           +YP +  W G S    +  L  + V        R+ L+E ++ +G   +L +D PS+   
Sbjct: 62  EYPDYQQWMGLSDSIRSCCLIPQTV------SHRLRLYEREDHKGLMMELSEDCPSIQDR 115

Query: 134 GWASKDVGSLKVSSGAWVAYQYPGYRGYQYVL 165
              S ++ SL V  G WV Y+ P YRG QY+L
Sbjct: 116 FHLS-EIRSLHVLEGCWVLYELPNYRGRQYLL 146



 Score = 56.2 bits (134), Expect = 2e-08
 Identities = 24/68 (35%), Positives = 40/68 (58%)

Query: 14  LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73
           L L++ ED +G    L  DC ++ +R  L  +RS+ V  G WV +E P+++G+Q++L   
Sbjct: 90  LRLYEREDHKGLMMELSEDCPSIQDRFHLSEIRSLHVLEGCWVLYELPNYRGRQYLLRPQ 149

Query: 74  DYPRWSAW 81
           +Y R   W
Sbjct: 150 EYRRCQDW 157



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 24/71 (33%), Positives = 37/71 (52%), Gaps = 7/71 (9%)

Query: 107 RVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLE 166
           ++T +E   FQG  ++   D P+L           S++V SG W+ Y+ P Y+G QY+L 
Sbjct: 3   KITFYEDRAFQGRSYETTTDCPNLQPY---FSRCNSIRVESGCWMLYERPNYQGQQYLLR 59

Query: 167 RDRHSGEFCTY 177
           R    GE+  Y
Sbjct: 60  R----GEYPDY 66


>gi|148491074 crystallin, gamma B [Homo sapiens]
          Length = 175

 Score = 94.0 bits (232), Expect = 7e-20
 Identities = 55/182 (30%), Positives = 96/182 (52%), Gaps = 14/182 (7%)

Query: 14  LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73
           +T +++  FQGR     +DC N+  +    R  S++VE+G W+ +E P++QG Q+ L +G
Sbjct: 4   ITFYEDRAFQGRSYECTTDCPNL--QPYFSRCNSIRVESGCWMIYERPNYQGHQYFLRRG 61

Query: 74  DYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYPSLPSM 133
           +YP +  W G S    +  L     +  +    R+ +++ D  +G   +L DD  S+   
Sbjct: 62  EYPDYQQWMGLSDSIRSCCL-----IPPHSGAYRMKIYDRDELRGQMSELTDDCISVQDR 116

Query: 134 GWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGELGTQAHTGQLQSIR 193
            +   ++ SL V  G+W+ Y+ P YRG QY+L      GE+  + + G  A   ++ S+R
Sbjct: 117 -FHLTEIHSLNVLEGSWILYEMPNYRGRQYLL----RPGEYRRFLDWG--APNAKVGSLR 169

Query: 194 RV 195
           RV
Sbjct: 170 RV 171



 Score = 46.6 bits (109), Expect = 1e-05
 Identities = 24/71 (33%), Positives = 37/71 (52%), Gaps = 7/71 (9%)

Query: 107 RVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLE 166
           ++T +E   FQG  ++   D P+L           S++V SG W+ Y+ P Y+G+QY L 
Sbjct: 3   KITFYEDRAFQGRSYECTTDCPNLQPY---FSRCNSIRVESGCWMIYERPNYQGHQYFLR 59

Query: 167 RDRHSGEFCTY 177
           R    GE+  Y
Sbjct: 60  R----GEYPDY 66


>gi|62988361 absent in melanoma 1 [Homo sapiens]
          Length = 1723

 Score = 90.1 bits (222), Expect = 1e-18
 Identities = 54/173 (31%), Positives = 91/173 (52%), Gaps = 20/173 (11%)

Query: 9    PAPASLTLWDEEDFQGRRCRLLSDCANVCERGG----------LP--RVRSVKVENGVWV 56
            P    + ++++  F+G+   L +   +    GG          LP   V S+KV  G+WV
Sbjct: 1215 PTDPKVVVYEKPFFEGKCVELETGMCSFVMEGGETEEATGDDHLPFTSVGSMKVLRGIWV 1274

Query: 57   AFEYPDFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNF 116
            A+E P F G Q++LE+G+Y  W AW G     + +L S RP+L  + +++ + ++   NF
Sbjct: 1275 AYEKPGFTGHQYLLEEGEYRDWKAWGG----YNGELQSLRPIL-GDFSNAHMIMYSEKNF 1329

Query: 117  --QGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLER 167
              +G   D++    +L   G+  K   S+ V SG WVAY+ P + G QY+L++
Sbjct: 1330 GSKGSSIDVLGIVANLKETGYGVK-TQSINVLSGVWVAYENPDFTGEQYILDK 1381



 Score = 84.0 bits (206), Expect = 8e-17
 Identities = 60/198 (30%), Positives = 94/198 (47%), Gaps = 26/198 (13%)

Query: 14   LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73
            + L+ E +  G       D   +   G + +  S+KV  G W+ +E P FQG  FILE G
Sbjct: 1125 IDLFTEPEGLGILSSYFDDTEEMQGFGVMQKTCSMKVHWGTWLIYEEPGFQGVPFILEPG 1184

Query: 74   DYPRWSAWSGSSSHNSNQLLSFRPVLCANH-----NDSRVTLFEGDNFQGCKFDLVDDYP 128
            +YP  S W   +++    + S RP+           D +V ++E   F+G   +L     
Sbjct: 1185 EYPDLSFWDTEAAY----IGSMRPLKMGGRKVEFPTDPKVVVYEKPFFEGKCVELETGMC 1240

Query: 129  SLPSMGWASKD-----------VGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTY 177
            S    G  +++           VGS+KV  G WVAY+ PG+ G+QY+LE     GE+  +
Sbjct: 1241 SFVMEGGETEEATGDDHLPFTSVGSMKVLRGIWVAYEKPGFTGHQYLLE----EGEYRDW 1296

Query: 178  GELGTQAHTGQLQSIRRV 195
               G   + G+LQS+R +
Sbjct: 1297 KAWG--GYNGELQSLRPI 1312



 Score = 79.3 bits (194), Expect = 2e-15
 Identities = 52/165 (31%), Positives = 81/165 (49%), Gaps = 14/165 (8%)

Query: 12   ASLTLWDEEDF--QGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFI 69
            A + ++ E++F  +G    +L   AN+ E G   + +S+ V +GVWVA+E PDF G+Q+I
Sbjct: 1319 AHMIMYSEKNFGSKGSSIDVLGIVANLKETGYGVKTQSINVLSGVWVAYENPDFTGEQYI 1378

Query: 70   LEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSR----VTLFEGDNFQGCKFDLVD 125
            L+KG Y  +  W G +     ++ S +P+   +    R    + LF    FQG       
Sbjct: 1379 LDKGFYTSFEDWGGKNC----KISSVQPICLDSFTGPRRRNQIHLFSEPQFQGHS----Q 1430

Query: 126  DYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRH 170
             +    S    S    S +VS G+WV Y    + G QYVLE   +
Sbjct: 1431 SFEETTSQIDDSFSTKSCRVSGGSWVVYDGENFTGNQYVLEEGHY 1475



 Score = 71.2 bits (173), Expect = 5e-13
 Identities = 46/150 (30%), Positives = 78/150 (52%), Gaps = 8/150 (5%)

Query: 16   LWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKGDY 75
            L+ E  FQG         + + +       +S +V  G WV ++  +F G Q++LE+G Y
Sbjct: 1419 LFSEPQFQGHSQSFEETTSQIDDSFS---TKSCRVSGGSWVVYDGENFTGNQYVLEEGHY 1475

Query: 76   PRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYPSLPSMGW 135
            P  SA  G     + + L F  V     ++  + LFE ++F+G K +L  +  +L S+G+
Sbjct: 1476 PCLSA-MGCPPGATFKSLRFIDV---EFSEPTIILFEREDFKGKKIELNAETVNLRSLGF 1531

Query: 136  ASKDVGSLKVSSGAWVAYQYPGYRGYQYVL 165
             +  + S++V  G WV Y+Y  YRG Q++L
Sbjct: 1532 -NTQIRSVQVIGGIWVTYEYGSYRGRQFLL 1560



 Score = 65.1 bits (157), Expect = 4e-11
 Identities = 43/166 (25%), Positives = 70/166 (42%), Gaps = 10/166 (6%)

Query: 9    PAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQF 68
            P P  + ++ E D   +   + SD  + C    L  V  +KV  G W+ +E P+F+G   
Sbjct: 1019 PRPGKVVIYSEPDVSEKCIEVFSDIQD-CSSWSLSPVILIKVVRGCWILYEQPNFEGHSI 1077

Query: 69   ILEKGDYPRWSAWS-GSSSHNSNQLLSFRPVLCA-------NHNDSRVTLFEGDNFQGCK 120
             LE+G+      W          +  S +PV+         ++  S + LF      G  
Sbjct: 1078 PLEEGELELSGLWGIEDILERHEEAESDKPVVIGSIRHVVQDYRVSHIDLFTEPEGLGIL 1137

Query: 121  FDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLE 166
                DD   +   G   K   S+KV  G W+ Y+ PG++G  ++LE
Sbjct: 1138 SSYFDDTEEMQGFGVMQKTC-SMKVHWGTWLIYEEPGFQGVPFILE 1182



 Score = 63.2 bits (152), Expect = 1e-10
 Identities = 29/85 (34%), Positives = 51/85 (60%), Gaps = 5/85 (5%)

Query: 13   SLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEK 72
            ++ L++ EDF+G++  L ++  N+   G   ++RSV+V  G+WV +EY  ++G+QF+L  
Sbjct: 1503 TIILFEREDFKGKKIELNAETVNLRSLGFNTQIRSVQVIGGIWVTYEYGSYRGRQFLLSP 1562

Query: 73   GDYPRWSAWSGSSSHNSNQLLSFRP 97
             + P W  +SG       Q+ S RP
Sbjct: 1563 AEVPNWYEFSG-----CRQIGSLRP 1582


>gi|90403579 beta-gamma crystallin domain containing 3 [Homo
           sapiens]
          Length = 1022

 Score = 89.4 bits (220), Expect = 2e-18
 Identities = 56/132 (42%), Positives = 78/132 (59%), Gaps = 7/132 (5%)

Query: 40  GGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVL 99
           G   R+ S++V  GVWVA+E   F+GQQF+LE+GD+   +A    SS     +LSFR  L
Sbjct: 563 GDFHRIGSIRVIGGVWVAYEKEHFKGQQFLLEEGDFEDSNACGALSS----PILSFR-YL 617

Query: 100 CANHNDSRVTLFEGDNFQGCKFDLVD-DYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGY 158
            AN  +S VTLFE D   G   D+ + +   L  +G+ SK   S+ V SG WVAYQ   +
Sbjct: 618 QANFIESSVTLFESDLESGKFIDITNQEISDLEEIGFGSK-TRSIHVKSGVWVAYQQKFF 676

Query: 159 RGYQYVLERDRH 170
            G QY+LE+ ++
Sbjct: 677 CGEQYILEKGKY 688



 Score = 63.2 bits (152), Expect = 1e-10
 Identities = 45/147 (30%), Positives = 75/147 (51%), Gaps = 14/147 (9%)

Query: 12  ASLTLWDEEDFQGRRCRLLS-DCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFIL 70
           +S+TL++ +   G+   + + + +++ E G   + RS+ V++GVWVA++   F G+Q+IL
Sbjct: 624 SSVTLFESDLESGKFIDITNQEISDLEEIGFGSKTRSIHVKSGVWVAYQQKFFCGEQYIL 683

Query: 71  EKGDYPRWSAWSGSSSHNSNQLLSFRPV----LCANHNDSRVTLFEGDNFQGCKFDLVDD 126
           EKG Y  +  W GS    +N ++S RP+    L  N     +  F    FQG   D  ++
Sbjct: 684 EKGKYKCFFDWGGS----NNIIMSIRPIQLEPLGINEPPHLLKAFSKPGFQGECIDFTEE 739

Query: 127 YPSLPSMGWASKDVGSLKVSSGAWVAY 153
              L S+        S KV  G W+ Y
Sbjct: 740 TSDLTSLMPC-----SFKVLRGCWLLY 761



 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 33/128 (25%), Positives = 64/128 (50%), Gaps = 16/128 (12%)

Query: 47  SVKVENGVWVAFEYPDFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHN-- 104
           S  V++GVW+A+   +F+GQ  +LE+          G    ++ ++ S  P+        
Sbjct: 475 SFTVKSGVWLAYPDINFKGQATVLEEDH--------GLFEISTAEMKSLHPLQMGGLKVE 526

Query: 105 ---DSRVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKD---VGSLKVSSGAWVAYQYPGY 158
              + +V ++E  +F G   +  +   S+P+    + D   +GS++V  G WVAY+   +
Sbjct: 527 MPMNLKVIIYEKPHFHGQAKEFSEHIDSVPNFLKNNGDFHRIGSIRVIGGVWVAYEKEHF 586

Query: 159 RGYQYVLE 166
           +G Q++LE
Sbjct: 587 KGQQFLLE 594



 Score = 48.9 bits (115), Expect = 3e-06
 Identities = 37/131 (28%), Positives = 57/131 (43%), Gaps = 4/131 (3%)

Query: 48  VKVENGVWVAFEYPDFQGQQFILEKGDYPRWSAW--SGSSSHNSNQLLSFRPVLCANHND 105
           +KV  G W+ +E P F+GQ+ +LE+G+      W          N +L     +  + + 
Sbjct: 381 IKVVRGCWILYEKPHFRGQKCVLEEGEKVLNRDWILQNRRHPQRNFILGSLKRVLKDCSI 440

Query: 106 SRVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVL 165
             + LF   +   C   +    P+L  +   SK V S  V SG W+AY    ++G   VL
Sbjct: 441 PEIELFPQSDPACCPVYIQRAVPNLEELN-ISKSV-SFTVKSGVWLAYPDINFKGQATVL 498

Query: 166 ERDRHSGEFCT 176
           E D    E  T
Sbjct: 499 EEDHGLFEIST 509



 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 22/70 (31%), Positives = 40/70 (57%)

Query: 13  SLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEK 72
           S++L+  E  +GR   L     +V  +      +SV V++G+W+A+E  +F G+Q +L  
Sbjct: 805 SISLFALEHCEGRELHLEEAVNSVLNKDLHFYTQSVWVKSGLWIAYEGSNFLGRQILLRP 864

Query: 73  GDYPRWSAWS 82
            + P W+A+S
Sbjct: 865 NEIPNWTAFS 874



 Score = 32.7 bits (73), Expect = 0.20
 Identities = 31/123 (25%), Positives = 57/123 (46%), Gaps = 14/123 (11%)

Query: 47  SVKVENGVWVAFEYPDFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDS 106
           S KV  G W+ +   D      +LE+G Y   ++    +S    ++ S +P+       S
Sbjct: 750 SFKVLRGCWLLYYQEDMFVNHCVLEEGLYADLTSCGCPAS----KVKSLKPIDYVFEEPS 805

Query: 107 RVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVG----SLKVSSGAWVAYQYPGYRGYQ 162
            ++LF  ++ +G +  L +   S+      +KD+     S+ V SG W+AY+   + G Q
Sbjct: 806 -ISLFALEHCEGRELHLEEAVNSV-----LNKDLHFYTQSVWVKSGLWIAYEGSNFLGRQ 859

Query: 163 YVL 165
            +L
Sbjct: 860 ILL 862



 Score = 30.8 bits (68), Expect = 0.78
 Identities = 14/41 (34%), Positives = 24/41 (58%), Gaps = 1/41 (2%)

Query: 127 YPSLP-SMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLE 166
           Y ++P +  W+  +   +KV  G W+ Y+ P +RG + VLE
Sbjct: 364 YCNIPDATSWSFPNGVLIKVVRGCWILYEKPHFRGQKCVLE 404


>gi|13377002 crystallin, gamma D [Homo sapiens]
          Length = 174

 Score = 88.6 bits (218), Expect = 3e-18
 Identities = 56/181 (30%), Positives = 91/181 (50%), Gaps = 16/181 (8%)

Query: 14  LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73
           +TL+++  FQGR     SD  N+  +  L R  S +V++G W+ +E P++ G Q+ L +G
Sbjct: 4   ITLYEDRGFQGRHYECSSDHPNL--QPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRRG 61

Query: 74  DYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDS-RVTLFEGDNFQGCKFDLVDDYPSLPS 132
           DY     W G S        S R      H+ S R+ L+E ++++G   +  +D   L  
Sbjct: 62  DYADHQQWMGLSD-------SVRSCRLIPHSGSHRIRLYEREDYRGQMIEFTEDCSCLQD 114

Query: 133 MGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGELG-TQAHTGQLQS 191
             +   ++ SL V  G+WV Y+   YRG QY+L      G++  Y + G T A  G L+ 
Sbjct: 115 R-FRFNEIHSLNVLEGSWVLYELSNYRGRQYLL----MPGDYRRYQDWGATNARVGSLRR 169

Query: 192 I 192
           +
Sbjct: 170 V 170



 Score = 46.6 bits (109), Expect = 1e-05
 Identities = 23/61 (37%), Positives = 35/61 (57%), Gaps = 3/61 (4%)

Query: 107 RVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLE 166
           ++TL+E   FQG  ++   D+P+L    + S+   S +V SG W+ Y+ P Y G QY L 
Sbjct: 3   KITLYEDRGFQGRHYECSSDHPNL--QPYLSR-CNSARVDSGCWMLYEQPNYSGLQYFLR 59

Query: 167 R 167
           R
Sbjct: 60  R 60


>gi|89886227 absent in melanoma 1-like [Homo sapiens]
          Length = 616

 Score = 87.8 bits (216), Expect = 5e-18
 Identities = 53/164 (32%), Positives = 82/164 (50%), Gaps = 11/164 (6%)

Query: 9   PAPASLTLWDEEDFQGRRCRLLSDCANV-----CERGGLPRVRSVKVENGVWVAFEYPDF 63
           P      +++   FQGR   +  D  N+      +   L  V S++V  G WV +E   F
Sbjct: 120 PGEPRAVVYEAPGFQGRSWEVSRDIYNLQQPEDSQSPHLASVGSLRVLGGCWVGYEKEGF 179

Query: 64  QGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDL 123
           +G Q++LE+G+YP WS W G      ++LL+   V+  +  D  V LFE  +F+G   ++
Sbjct: 180 RGHQYLLEEGEYPDWSHWGG-----YDELLTSLRVIRTDFGDPAVVLFEAMDFEGHGVEV 234

Query: 124 VDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLER 167
               P +  +        ++ V SG WVAYQ  G+ G QYVLE+
Sbjct: 235 SKALPDV-ELVQHGPSTQAIHVLSGVWVAYQEVGFSGEQYVLEK 277



 Score = 81.3 bits (199), Expect = 5e-16
 Identities = 57/186 (30%), Positives = 89/186 (47%), Gaps = 18/186 (9%)

Query: 13  SLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEK 72
           ++ L++  DF+G    +     +V      P  +++ V +GVWVA++   F G+Q++LEK
Sbjct: 218 AVVLFEAMDFEGHGVEVSKALPDVELVQHGPSTQAIHVLSGVWVAYQEVGFSGEQYVLEK 277

Query: 73  GDYPRWSAWSGSSSHNSNQLLSFRPVLCANHND----SRVTLFEGDNFQGCKFDLVDDYP 128
           G Y     W   +S     L S +PVL    +D    S++ LF   +F G  F   DD  
Sbjct: 278 GVYRNCEDWGAGNS----TLASLQPVLQVGEHDLHFVSKIQLFSRPDFLGDHFSFEDDQA 333

Query: 129 SLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGELGTQAHT-- 186
           +LP    AS    S +V  G+W+ +    + G Q++L      GEF T   +G  A T  
Sbjct: 334 ALP----ASFRPQSCRVHGGSWILFDETNFEGDQHILS----EGEFPTLTAMGCLASTVL 385

Query: 187 GQLQSI 192
           G LQ +
Sbjct: 386 GSLQKV 391



 Score = 75.1 bits (183), Expect = 4e-14
 Identities = 50/164 (30%), Positives = 80/164 (48%), Gaps = 9/164 (5%)

Query: 14  LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73
           ++L+ EE  +G + +L     N        +V S  V  G+W+ +  P F+   +ILE G
Sbjct: 30  ISLFSEEGLKGEQVKLTEALKNSQGLEKPLQVASATVSAGLWLLYPKPLFEDTPYILEPG 89

Query: 74  DYPRWSAWSGSSSHNSNQLLSFRPVLCAN---HNDSRVTLFEGDNFQGCKFDLVDDYPSL 130
           +YP   AW G+S  +   L   R + C +     + R  ++E   FQG  +++  D  +L
Sbjct: 90  EYPTSEAW-GTSDPSVGSLKPMR-LGCPSVEKPGEPRAVVYEAPGFQGRSWEVSRDIYNL 147

Query: 131 P----SMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRH 170
                S       VGSL+V  G WV Y+  G+RG+QY+LE   +
Sbjct: 148 QQPEDSQSPHLASVGSLRVLGGCWVGYEKEGFRGHQYLLEEGEY 191



 Score = 54.7 bits (130), Expect = 5e-08
 Identities = 39/157 (24%), Positives = 77/157 (49%), Gaps = 14/157 (8%)

Query: 12  ASLTLWDEEDFQGRRCRLLSDCANVCERGGLP---RVRSVKVENGVWVAFEYPDFQGQQF 68
           + + L+   DF G       D A       LP   R +S +V  G W+ F+  +F+G Q 
Sbjct: 311 SKIQLFSRPDFLGDHFSFEDDQA------ALPASFRPQSCRVHGGSWILFDETNFEGDQH 364

Query: 69  ILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYP 128
           IL +G++P  +A    +S     +L     +  + ++  + L+  + F+G + +L  +  
Sbjct: 365 ILSEGEFPTLTAMGCLAS----TVLGSLQKVSLHFSEPSIFLYGLECFEGKEIELSREVR 420

Query: 129 SLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVL 165
           SL + G+ +  V S+++  G WV  ++  +RG Q+++
Sbjct: 421 SLQAEGF-NNHVLSVRIKGGIWVLCEHSDFRGRQWLV 456



 Score = 46.6 bits (109), Expect = 1e-05
 Identities = 21/72 (29%), Positives = 41/72 (56%)

Query: 13  SLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEK 72
           S+ L+  E F+G+   L  +  ++   G    V SV+++ G+WV  E+ DF+G+Q+++  
Sbjct: 399 SIFLYGLECFEGKEIELSREVRSLQAEGFNNHVLSVRIKGGIWVLCEHSDFRGRQWLVGS 458

Query: 73  GDYPRWSAWSGS 84
            +   W  +SG+
Sbjct: 459 CEITNWLTYSGT 470


>gi|87298939 hypothetical protein LOC131831 [Homo sapiens]
          Length = 663

 Score = 30.0 bits (66), Expect = 1.3
 Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 5/61 (8%)

Query: 54  VWVAFEYPDFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEG 113
           VWV   Y +  G Q+  + G+  R  AW+ S+S  S+  +SF+PV  A +    V + E 
Sbjct: 499 VWV---YINILGGQYSDQAGN--RIRAWNWSNSITSSPFVSFKPVFLALNRYIGVRILEQ 553

Query: 114 D 114
           D
Sbjct: 554 D 554


>gi|134244285 Notch homolog 3 [Homo sapiens]
          Length = 2321

 Score = 29.3 bits (64), Expect = 2.3
 Identities = 13/20 (65%), Positives = 14/20 (70%), Gaps = 1/20 (5%)

Query: 23  QGRRCRLLSDCA-NVCERGG 41
           QGR+C LLS C  N CE GG
Sbjct: 765 QGRQCELLSPCTPNPCEHGG 784


>gi|134031945 SCO-spondin [Homo sapiens]
          Length = 5147

 Score = 28.1 bits (61), Expect = 5.0
 Identities = 13/36 (36%), Positives = 18/36 (50%), Gaps = 5/36 (13%)

Query: 97  PVLCANHNDSRVTLFEGDNF-----QGCKFDLVDDY 127
           P  CA   D     F+G ++     QGC++ LV DY
Sbjct: 561 PAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDY 596


>gi|4557529 post-synaptic density protein 95 isoform 1 [Homo
           sapiens]
          Length = 767

 Score = 27.3 bits (59), Expect = 8.6
 Identities = 40/183 (21%), Positives = 71/183 (38%), Gaps = 35/183 (19%)

Query: 18  DEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKGDYPR 77
           DEE +Q RR    S+  ++   G +P  R  +VE   W   +  D               
Sbjct: 510 DEEWWQARRVHSDSETDDI---GFIPSKR--RVERREWSRLKAKD--------------- 549

Query: 78  WSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYPSLPSMGWAS 137
           W + SGS     + +LS+  V     + +R  +  G        DL+ ++P         
Sbjct: 550 WGSSSGSQGREDS-VLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPD-------- 600

Query: 138 KDVGSLKVSSGAWVAYQYPGYRGYQYV-----LERDRHSGEFCTYGELGTQAHTGQLQSI 192
           K    +  ++     Y+  G R Y +V     +E+D  + +F   G+  +  +   +QS+
Sbjct: 601 KFGSCVPHTTRPKREYEIDG-RDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSV 659

Query: 193 RRV 195
           R V
Sbjct: 660 REV 662


>gi|192447426 post-synaptic density protein 95 isoform 2 [Homo
           sapiens]
          Length = 721

 Score = 27.3 bits (59), Expect = 8.6
 Identities = 40/183 (21%), Positives = 71/183 (38%), Gaps = 35/183 (19%)

Query: 18  DEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKGDYPR 77
           DEE +Q RR    S+  ++   G +P  R  +VE   W   +  D               
Sbjct: 464 DEEWWQARRVHSDSETDDI---GFIPSKR--RVERREWSRLKAKD--------------- 503

Query: 78  WSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYPSLPSMGWAS 137
           W + SGS     + +LS+  V     + +R  +  G        DL+ ++P         
Sbjct: 504 WGSSSGSQGREDS-VLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPD-------- 554

Query: 138 KDVGSLKVSSGAWVAYQYPGYRGYQYV-----LERDRHSGEFCTYGELGTQAHTGQLQSI 192
           K    +  ++     Y+  G R Y +V     +E+D  + +F   G+  +  +   +QS+
Sbjct: 555 KFGSCVPHTTRPKREYEIDG-RDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSV 613

Query: 193 RRV 195
           R V
Sbjct: 614 REV 616


>gi|218156340 chapsyn-110 isoform 3 [Homo sapiens]
          Length = 749

 Score = 27.3 bits (59), Expect = 8.6
 Identities = 44/192 (22%), Positives = 72/192 (37%), Gaps = 33/192 (17%)

Query: 18  DEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILE-KGDYP 76
           D+E +Q RR  L  D     E G +P  R  +VE       +   F  +  +++ KGD P
Sbjct: 472 DDEWWQARRVMLEGDSE---EMGVIPSKR--RVERKERARLKTVKFNAKPGVIDSKGDIP 526

Query: 77  RWSAWSGSSSHNSNQ---LLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYPS---- 129
                   +     Q   +LS+ PV     N +R  +  G        DL+ ++P     
Sbjct: 527 GLGDDGYGTKTLRGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKFGS 586

Query: 130 -LPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYV-----LERDRHSGEFCTYGELGTQ 183
            +P      +D             Y+  G R Y +V     +E+D    +F   G+    
Sbjct: 587 CVPHTTRPKRD-------------YEVDG-RDYHFVISREQMEKDIQEHKFIEAGQYNDN 632

Query: 184 AHTGQLQSIRRV 195
            +   +QS+R V
Sbjct: 633 LYGTSVQSVRFV 644


>gi|218156270 chapsyn-110 isoform 4 [Homo sapiens]
          Length = 334

 Score = 27.3 bits (59), Expect = 8.6
 Identities = 44/192 (22%), Positives = 72/192 (37%), Gaps = 33/192 (17%)

Query: 18  DEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILE-KGDYP 76
           D+E +Q RR  L  D     E G +P  R  +VE       +   F  +  +++ KGD P
Sbjct: 57  DDEWWQARRVMLEGDSE---EMGVIPSKR--RVERKERARLKTVKFNAKPGVIDSKGDIP 111

Query: 77  RWSAWSGSSSHNSNQ---LLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYPS---- 129
                   +     Q   +LS+ PV     N +R  +  G        DL+ ++P     
Sbjct: 112 GLGDDGYGTKTLRGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKFGS 171

Query: 130 -LPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYV-----LERDRHSGEFCTYGELGTQ 183
            +P      +D             Y+  G R Y +V     +E+D    +F   G+    
Sbjct: 172 CVPHTTRPKRD-------------YEVDG-RDYHFVISREQMEKDIQEHKFIEAGQYNDN 217

Query: 184 AHTGQLQSIRRV 195
            +   +QS+R V
Sbjct: 218 LYGTSVQSVRFV 229


>gi|45120115 hypothetical protein LOC56905 [Homo sapiens]
          Length = 1047

 Score = 27.3 bits (59), Expect = 8.6
 Identities = 21/72 (29%), Positives = 28/72 (38%), Gaps = 3/72 (4%)

Query: 4   APAPGPAPASLTLWD---EEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEY 60
           AP  GPAPAS +      E+ F G    L    +         ++R      G W    +
Sbjct: 746 APVAGPAPASTSAPGDSLEQHFTGLHASLCDAISGSVAHSPPEKLREWLETAGPWGQAAW 805

Query: 61  PDFQGQQFILEK 72
            D QG Q +L K
Sbjct: 806 QDCQGVQGLLAK 817


>gi|95147342 chromodomain helicase DNA binding protein 9 [Homo
           sapiens]
          Length = 2881

 Score = 27.3 bits (59), Expect = 8.6
 Identities = 16/38 (42%), Positives = 22/38 (57%), Gaps = 1/38 (2%)

Query: 79  SAWSGSSSHNS-NQLLSFRPVLCANHNDSRVTLFEGDN 115
           S +S SS+H S N LL    VL +NH +  ++ F G N
Sbjct: 272 SHYSFSSNHISPNSLLQSSAVLASNHTNQTLSDFTGSN 309


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.441 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,930,432
Number of Sequences: 37866
Number of extensions: 411010
Number of successful extensions: 1216
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1098
Number of HSP's gapped (non-prelim): 58
length of query: 197
length of database: 18,247,518
effective HSP length: 97
effective length of query: 100
effective length of database: 14,574,516
effective search space: 1457451600
effective search space used: 1457451600
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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