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Search of human proteins with 16936528
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens]
(298 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens] 605 e-173
gi|166362719 cyclin-dependent kinase 2 isoform 2 [Homo sapiens] 515 e-146
gi|4557439 cyclin-dependent kinase 3 [Homo sapiens] 467 e-132
gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens] 397 e-111
gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens] 395 e-110
gi|4826675 cyclin-dependent kinase 5 [Homo sapiens] 350 9e-97
gi|197333744 PCTAIRE protein kinase 1 isoform 2 [Homo sapiens] 317 6e-87
gi|5453860 PCTAIRE protein kinase 1 isoform 1 [Homo sapiens] 317 6e-87
gi|37595545 PCTAIRE protein kinase 2 [Homo sapiens] 316 2e-86
gi|47078233 PCTAIRE protein kinase 3 isoform a [Homo sapiens] 311 6e-85
gi|47078231 PCTAIRE protein kinase 3 isoform b [Homo sapiens] 311 6e-85
gi|47078229 PCTAIRE protein kinase 3 isoform b [Homo sapiens] 311 6e-85
gi|6912584 PFTAIRE protein kinase 1 [Homo sapiens] 287 9e-78
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 270 9e-73
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 270 9e-73
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 270 9e-73
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 270 9e-73
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof... 270 9e-73
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 270 9e-73
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 268 3e-72
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 268 3e-72
gi|223718134 cyclin-dependent kinase 6 [Homo sapiens] 268 4e-72
gi|4502741 cyclin-dependent kinase 6 [Homo sapiens] 268 4e-72
gi|4502743 cyclin-dependent kinase 7 [Homo sapiens] 266 2e-71
gi|21040235 PFTAIRE protein kinase 2 [Homo sapiens] 262 3e-70
gi|148596926 cyclin-dependent kinase 10 isoform a [Homo sapiens] 258 4e-69
gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens] 244 5e-65
gi|4502735 cyclin-dependent kinase 4 [Homo sapiens] 243 1e-64
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 237 8e-63
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 237 8e-63
>gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens]
Length = 298
Score = 605 bits (1559), Expect = e-173
Identities = 298/298 (100%), Positives = 298/298 (100%)
Query: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH
Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
Query: 61 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 120
PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS
Sbjct: 61 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 120
Query: 121 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY 180
HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY
Sbjct: 121 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY 180
Query: 181 STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF 240
STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF
Sbjct: 181 STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF 240
Query: 241 PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL 298
PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
Sbjct: 241 PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL 298
>gi|166362719 cyclin-dependent kinase 2 isoform 2 [Homo sapiens]
Length = 264
Score = 515 bits (1327), Expect = e-146
Identities = 264/298 (88%), Positives = 264/298 (88%), Gaps = 34/298 (11%)
Query: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH
Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
Query: 61 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 120
PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS
Sbjct: 61 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 120
Query: 121 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY 180
HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHE
Sbjct: 121 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHE------------------ 162
Query: 181 STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF 240
VTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF
Sbjct: 163 ----------------VTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF 206
Query: 241 PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL 298
PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
Sbjct: 207 PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL 264
>gi|4557439 cyclin-dependent kinase 3 [Homo sapiens]
Length = 305
Score = 467 bits (1202), Expect = e-132
Identities = 227/297 (76%), Positives = 259/297 (87%), Gaps = 1/297 (0%)
Query: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
M+ FQKVEKIGEGTYGVVYKA+N+ TG++VALKKIRLD E EGVPSTAIREISLLKEL H
Sbjct: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60
Query: 61 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 120
PNIV+LLDV+H E KLYLVFEFL QDLKK+MD++ + +PL LIKSYLFQLLQG++FCHS
Sbjct: 61 PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHS 120
Query: 121 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY 180
HRV+HRDLKPQNLLIN GAIKLADFGLARAFGVP+RTYTHEVVTLWYRAPEILLG K+Y
Sbjct: 121 HRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFY 180
Query: 181 STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF 240
+TAVDIWS+GCIFAEMVTR+ALFPGDSEIDQLFRIFR LGTP E WPGVT +PDYK SF
Sbjct: 181 TTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGSF 240
Query: 241 PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLR 297
PKW R+ ++VP L+ +GR LL Q+L YDP++RI+AK ALAHP+F +P P R
Sbjct: 241 PKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSS-PEPSPAAR 296
>gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens]
Length = 297
Score = 397 bits (1019), Expect = e-111
Identities = 196/295 (66%), Positives = 235/295 (79%), Gaps = 3/295 (1%)
Query: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
ME++ K+EKIGEGTYGVVYK R+K TG+VVA+KKIRL++E EGVPSTAIREISLLKEL H
Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
Query: 61 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTG--IPLPLIKSYLFQLLQGLAFC 118
PNIV L DV+ +++LYL+FEFL DLKK++D S G + L+KSYL+Q+LQG+ FC
Sbjct: 61 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLD-SIPPGQYMDSSLVKSYLYQILQGIVFC 119
Query: 119 HSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCK 178
HS RVLHRDLKPQNLLI+ +G IKLADFGLARAFG+P+R YTHEVVTLWYR+PE+LLG
Sbjct: 120 HSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSA 179
Query: 179 YYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKP 238
YST VDIWS+G IFAE+ T++ LF GDSEIDQLFRIFR LGTP+ VWP V S+ DYK
Sbjct: 180 RYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKN 239
Query: 239 SFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPV 293
+FPKW + V LDE+G LLS+ML YDP KRIS K AL HP+F D+ +
Sbjct: 240 TFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQI 294
>gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens]
Length = 297
Score = 395 bits (1014), Expect = e-110
Identities = 194/295 (65%), Positives = 234/295 (79%), Gaps = 3/295 (1%)
Query: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
ME++ K+EKIGEGTYGVVYK R+K TG+VVA+KKIRL++E EGVPSTAIREISLLKEL H
Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
Query: 61 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTG--IPLPLIKSYLFQLLQGLAFC 118
PNIV L DV+ +++LYL+FEFL DLKK++D S G + L+KSYL+Q+LQG+ FC
Sbjct: 61 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLD-SIPPGQYMDSSLVKSYLYQILQGIVFC 119
Query: 119 HSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCK 178
HS RVLHRDLKPQNLLI+ +G IKLADFGLARAFG+P+R YTHE +TLWYR+PE+LLG
Sbjct: 120 HSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSA 179
Query: 179 YYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKP 238
YST VDIWS+G IFAE+ T++ LF GDSEIDQLFRIFR LGTP+ VWP V S+ DYK
Sbjct: 180 RYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKN 239
Query: 239 SFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPV 293
+FPKW + V LDE+G LLS+ML YDP KRIS K AL HP+F D+ +
Sbjct: 240 TFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQI 294
>gi|4826675 cyclin-dependent kinase 5 [Homo sapiens]
Length = 292
Score = 350 bits (898), Expect = 9e-97
Identities = 176/294 (59%), Positives = 219/294 (74%), Gaps = 4/294 (1%)
Query: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
M+ ++K+EKIGEGTYG V+KA+N+ T E+VALK++RLD + EGVPS+A+REI LLKEL H
Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
Query: 61 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 120
NIV+L DV+H++ KL LVFEF QDLKK+ D S + ++KS+LFQLL+GL FCHS
Sbjct: 61 KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFD-SCNGDLDPEIVKSFLFQLLKGLGFCHS 119
Query: 121 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY 180
VLHRDLKPQNLLIN G +KLADFGLARAFG+PVR Y+ EVVTLWYR P++L G K Y
Sbjct: 120 RNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLY 179
Query: 181 STAVDIWSLGCIFAEMVTR-RALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPS 239
ST++D+WS GCIFAE+ R LFPG+ DQL RIFR LGTP E WP +T +PDYKP
Sbjct: 180 STSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKP- 238
Query: 240 FPKW-ARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKP 292
+P + A VVP L+ GR LL +L +P +RISA+ AL HP+F D P
Sbjct: 239 YPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP 292
>gi|197333744 PCTAIRE protein kinase 1 isoform 2 [Homo sapiens]
Length = 502
Score = 317 bits (813), Expect = 6e-87
Identities = 159/287 (55%), Positives = 208/287 (72%), Gaps = 3/287 (1%)
Query: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
+E + K++K+GEGTY VYK ++KLT +VALK+IRL+ E EG P TAIRE+SLLK+L H
Sbjct: 168 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE-EGAPCTAIREVSLLKDLKH 226
Query: 61 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 120
NIV L D+IHTE L LVFE+L +DLK+++D I + +K +LFQLL+GLA+CH
Sbjct: 227 ANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNI-INMHNVKLFLFQLLRGLAYCHR 285
Query: 121 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY 180
+VLHRDLKPQNLLIN G +KLADFGLARA +P +TY++EVVTLWYR P+ILLG Y
Sbjct: 286 QKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDY 345
Query: 181 STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKP-S 239
ST +D+W +GCIF EM T R LFPG + +QL IFR LGTP E WPG+ S ++K +
Sbjct: 346 STQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYN 405
Query: 240 FPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFF 286
+PK+ + P LD DG LL+++L ++ RISA+ A+ HPFF
Sbjct: 406 YPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFF 452
>gi|5453860 PCTAIRE protein kinase 1 isoform 1 [Homo sapiens]
Length = 496
Score = 317 bits (813), Expect = 6e-87
Identities = 159/287 (55%), Positives = 208/287 (72%), Gaps = 3/287 (1%)
Query: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
+E + K++K+GEGTY VYK ++KLT +VALK+IRL+ E EG P TAIRE+SLLK+L H
Sbjct: 162 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE-EGAPCTAIREVSLLKDLKH 220
Query: 61 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 120
NIV L D+IHTE L LVFE+L +DLK+++D I + +K +LFQLL+GLA+CH
Sbjct: 221 ANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNI-INMHNVKLFLFQLLRGLAYCHR 279
Query: 121 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY 180
+VLHRDLKPQNLLIN G +KLADFGLARA +P +TY++EVVTLWYR P+ILLG Y
Sbjct: 280 QKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDY 339
Query: 181 STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKP-S 239
ST +D+W +GCIF EM T R LFPG + +QL IFR LGTP E WPG+ S ++K +
Sbjct: 340 STQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYN 399
Query: 240 FPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFF 286
+PK+ + P LD DG LL+++L ++ RISA+ A+ HPFF
Sbjct: 400 YPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFF 446
>gi|37595545 PCTAIRE protein kinase 2 [Homo sapiens]
Length = 523
Score = 316 bits (809), Expect = 2e-86
Identities = 155/290 (53%), Positives = 211/290 (72%), Gaps = 3/290 (1%)
Query: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
ME + K+EK+GEGTY VYK R+KLT +VALK+IRL+ E EG P TAIRE+SLLK+L H
Sbjct: 189 METYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKDLKH 247
Query: 61 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 120
NIV L D++HT+ L LVFE+L +DLK++MD + + +K +L+Q+L+GLA+CH
Sbjct: 248 ANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNI-MSMHNVKLFLYQILRGLAYCHR 306
Query: 121 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY 180
+VLHRDLKPQNLLIN +G +KLADFGLARA VP +TY++EVVTLWYR P++LLG Y
Sbjct: 307 RKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEY 366
Query: 181 STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKP-S 239
ST +D+W +GCIF EM + R LFPG + D+L IFR LGTP + WPG++S ++K +
Sbjct: 367 STQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGISSNEEFKNYN 426
Query: 240 FPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV 289
FPK+ Q P LD +G L+++ L Y+ KR+SA+ A+ H +F+ +
Sbjct: 427 FPKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYFRSL 476
>gi|47078233 PCTAIRE protein kinase 3 isoform a [Homo sapiens]
Length = 504
Score = 311 bits (796), Expect = 6e-85
Identities = 158/297 (53%), Positives = 210/297 (70%), Gaps = 3/297 (1%)
Query: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
+E + K++K+GEGTY V+K R+KLT +VALK+IRL+ E EG P TAIRE+SLLK L H
Sbjct: 171 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKNLKH 229
Query: 61 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 120
NIV L D+IHT+ L LVFE+L DLK+++D + + +K ++FQLL+GLA+CH
Sbjct: 230 ANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNL-MSMHNVKIFMFQLLRGLAYCHH 288
Query: 121 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY 180
++LHRDLKPQNLLIN G +KLADFGLARA VP +TY++EVVTLWYR P++LLG Y
Sbjct: 289 RKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEY 348
Query: 181 STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKP-S 239
ST +D+W +GCI EM T R LFPG + ++L IFR LGTP E WPGVT+ +++ S
Sbjct: 349 STPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYS 408
Query: 240 FPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHL 296
FP + Q P LD DG LLS +L Y+ R+SA+AAL+H +F+ + + V L
Sbjct: 409 FPCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYFRSLGERVHQL 465
>gi|47078231 PCTAIRE protein kinase 3 isoform b [Homo sapiens]
Length = 474
Score = 311 bits (796), Expect = 6e-85
Identities = 158/297 (53%), Positives = 210/297 (70%), Gaps = 3/297 (1%)
Query: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
+E + K++K+GEGTY V+K R+KLT +VALK+IRL+ E EG P TAIRE+SLLK L H
Sbjct: 141 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKNLKH 199
Query: 61 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 120
NIV L D+IHT+ L LVFE+L DLK+++D + + +K ++FQLL+GLA+CH
Sbjct: 200 ANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNL-MSMHNVKIFMFQLLRGLAYCHH 258
Query: 121 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY 180
++LHRDLKPQNLLIN G +KLADFGLARA VP +TY++EVVTLWYR P++LLG Y
Sbjct: 259 RKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEY 318
Query: 181 STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKP-S 239
ST +D+W +GCI EM T R LFPG + ++L IFR LGTP E WPGVT+ +++ S
Sbjct: 319 STPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYS 378
Query: 240 FPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHL 296
FP + Q P LD DG LLS +L Y+ R+SA+AAL+H +F+ + + V L
Sbjct: 379 FPCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYFRSLGERVHQL 435
>gi|47078229 PCTAIRE protein kinase 3 isoform b [Homo sapiens]
Length = 474
Score = 311 bits (796), Expect = 6e-85
Identities = 158/297 (53%), Positives = 210/297 (70%), Gaps = 3/297 (1%)
Query: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
+E + K++K+GEGTY V+K R+KLT +VALK+IRL+ E EG P TAIRE+SLLK L H
Sbjct: 141 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKNLKH 199
Query: 61 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 120
NIV L D+IHT+ L LVFE+L DLK+++D + + +K ++FQLL+GLA+CH
Sbjct: 200 ANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNL-MSMHNVKIFMFQLLRGLAYCHH 258
Query: 121 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY 180
++LHRDLKPQNLLIN G +KLADFGLARA VP +TY++EVVTLWYR P++LLG Y
Sbjct: 259 RKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEY 318
Query: 181 STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKP-S 239
ST +D+W +GCI EM T R LFPG + ++L IFR LGTP E WPGVT+ +++ S
Sbjct: 319 STPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYS 378
Query: 240 FPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHL 296
FP + Q P LD DG LLS +L Y+ R+SA+AAL+H +F+ + + V L
Sbjct: 379 FPCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYFRSLGERVHQL 435
>gi|6912584 PFTAIRE protein kinase 1 [Homo sapiens]
Length = 451
Score = 287 bits (734), Expect = 9e-78
Identities = 151/292 (51%), Positives = 202/292 (69%), Gaps = 6/292 (2%)
Query: 2 ENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHP 61
++++K+EK+GEG+Y VYK ++K+ G++VALK IRL E EG P TAIRE SLLK L H
Sbjct: 115 DSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEE-EGTPFTAIREASLLKGLKHA 173
Query: 62 NIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSH 121
NIV L D+IHT+ L LVFE++H DL ++MD G+ +K +LFQLL+GL++ H
Sbjct: 174 NIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHP-GGLHPDNVKLFLFQLLRGLSYIHQR 232
Query: 122 RVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYS 181
+LHRDLKPQNLLI+ G +KLADFGLARA VP TY++EVVTLWYR P++LLG YS
Sbjct: 233 YILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYS 292
Query: 182 TAVDIWSLGCIFAEMVTRRALFPGDSEI-DQLFRIFRTLGTPDEVVWPGVTSMPDYKPS- 239
T +D+W +GCIF EM+ A FPG +I DQL RIF LGTP+E WPGV S+P +KP
Sbjct: 293 TCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPER 352
Query: 240 FPKWARQDFSKVVPPLD--EDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV 289
F ++ ++ + L L S++L P R+SA+AAL+H +F D+
Sbjct: 353 FTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDL 404
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 270 bits (691), Expect = 9e-73
Identities = 133/297 (44%), Positives = 201/297 (67%), Gaps = 5/297 (1%)
Query: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
+E FQ + +I EGTYGVVY+A++K T E+VALK+++++ E EG P T++REI+ + + H
Sbjct: 411 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 470
Query: 61 PNIVKLLDVIHTEN--KLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFC 118
PNIV + +++ N K+Y+V ++ DLK M+ +P +K+ + QLL+G+
Sbjct: 471 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE-VKTLMIQLLRGVKHL 529
Query: 119 HSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCK 178
H + +LHRDLK NLL++ G +K+ DFGLAR +G P++ YT VVTLWYRAPE+LLG K
Sbjct: 530 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK 589
Query: 179 YYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKP 238
YSTAVD+WS+GCIF E++T++ LFPG SEIDQ+ ++F+ LGTP E +WPG + +P K
Sbjct: 590 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 649
Query: 239 -SFPKWARQDFSKVVPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPV 293
+F + + K L + G L+++ L Y P +RISA+ L H +F++ P+
Sbjct: 650 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPI 706
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 270 bits (691), Expect = 9e-73
Identities = 133/297 (44%), Positives = 201/297 (67%), Gaps = 5/297 (1%)
Query: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
+E FQ + +I EGTYGVVY+A++K T E+VALK+++++ E EG P T++REI+ + + H
Sbjct: 420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 479
Query: 61 PNIVKLLDVIHTEN--KLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFC 118
PNIV + +++ N K+Y+V ++ DLK M+ +P +K+ + QLL+G+
Sbjct: 480 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE-VKTLMIQLLRGVKHL 538
Query: 119 HSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCK 178
H + +LHRDLK NLL++ G +K+ DFGLAR +G P++ YT VVTLWYRAPE+LLG K
Sbjct: 539 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK 598
Query: 179 YYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKP 238
YSTAVD+WS+GCIF E++T++ LFPG SEIDQ+ ++F+ LGTP E +WPG + +P K
Sbjct: 599 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 658
Query: 239 -SFPKWARQDFSKVVPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPV 293
+F + + K L + G L+++ L Y P +RISA+ L H +F++ P+
Sbjct: 659 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPI 715
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 270 bits (691), Expect = 9e-73
Identities = 133/297 (44%), Positives = 201/297 (67%), Gaps = 5/297 (1%)
Query: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
+E FQ + +I EGTYGVVY+A++K T E+VALK+++++ E EG P T++REI+ + + H
Sbjct: 388 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 447
Query: 61 PNIVKLLDVIHTEN--KLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFC 118
PNIV + +++ N K+Y+V ++ DLK M+ +P +K+ + QLL+G+
Sbjct: 448 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE-VKTLMIQLLRGVKHL 506
Query: 119 HSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCK 178
H + +LHRDLK NLL++ G +K+ DFGLAR +G P++ YT VVTLWYRAPE+LLG K
Sbjct: 507 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK 566
Query: 179 YYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKP 238
YSTAVD+WS+GCIF E++T++ LFPG SEIDQ+ ++F+ LGTP E +WPG + +P K
Sbjct: 567 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 626
Query: 239 -SFPKWARQDFSKVVPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPV 293
+F + + K L + G L+++ L Y P +RISA+ L H +F++ P+
Sbjct: 627 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPI 683
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 270 bits (691), Expect = 9e-73
Identities = 133/297 (44%), Positives = 201/297 (67%), Gaps = 5/297 (1%)
Query: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
+E FQ + +I EGTYGVVY+A++K T E+VALK+++++ E EG P T++REI+ + + H
Sbjct: 377 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 436
Query: 61 PNIVKLLDVIHTEN--KLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFC 118
PNIV + +++ N K+Y+V ++ DLK M+ +P +K+ + QLL+G+
Sbjct: 437 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE-VKTLMIQLLRGVKHL 495
Query: 119 HSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCK 178
H + +LHRDLK NLL++ G +K+ DFGLAR +G P++ YT VVTLWYRAPE+LLG K
Sbjct: 496 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK 555
Query: 179 YYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKP 238
YSTAVD+WS+GCIF E++T++ LFPG SEIDQ+ ++F+ LGTP E +WPG + +P K
Sbjct: 556 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 615
Query: 239 -SFPKWARQDFSKVVPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPV 293
+F + + K L + G L+++ L Y P +RISA+ L H +F++ P+
Sbjct: 616 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPI 672
>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
3 [Homo sapiens]
Length = 526
Score = 270 bits (691), Expect = 9e-73
Identities = 133/297 (44%), Positives = 201/297 (67%), Gaps = 5/297 (1%)
Query: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
+E FQ + +I EGTYGVVY+A++K T E+VALK+++++ E EG P T++REI+ + + H
Sbjct: 166 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 225
Query: 61 PNIVKLLDVIHTEN--KLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFC 118
PNIV + +++ N K+Y+V ++ DLK M+ +P +K+ + QLL+G+
Sbjct: 226 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE-VKTLMIQLLRGVKHL 284
Query: 119 HSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCK 178
H + +LHRDLK NLL++ G +K+ DFGLAR +G P++ YT VVTLWYRAPE+LLG K
Sbjct: 285 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK 344
Query: 179 YYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKP 238
YSTAVD+WS+GCIF E++T++ LFPG SEIDQ+ ++F+ LGTP E +WPG + +P K
Sbjct: 345 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 404
Query: 239 -SFPKWARQDFSKVVPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPV 293
+F + + K L + G L+++ L Y P +RISA+ L H +F++ P+
Sbjct: 405 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPI 461
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 270 bits (691), Expect = 9e-73
Identities = 133/297 (44%), Positives = 201/297 (67%), Gaps = 5/297 (1%)
Query: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
+E FQ + +I EGTYGVVY+A++K T E+VALK+++++ E EG P T++REI+ + + H
Sbjct: 422 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 481
Query: 61 PNIVKLLDVIHTEN--KLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFC 118
PNIV + +++ N K+Y+V ++ DLK M+ +P +K+ + QLL+G+
Sbjct: 482 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE-VKTLMIQLLRGVKHL 540
Query: 119 HSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCK 178
H + +LHRDLK NLL++ G +K+ DFGLAR +G P++ YT VVTLWYRAPE+LLG K
Sbjct: 541 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK 600
Query: 179 YYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKP 238
YSTAVD+WS+GCIF E++T++ LFPG SEIDQ+ ++F+ LGTP E +WPG + +P K
Sbjct: 601 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 660
Query: 239 -SFPKWARQDFSKVVPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPV 293
+F + + K L + G L+++ L Y P +RISA+ L H +F++ P+
Sbjct: 661 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPI 717
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 268 bits (686), Expect = 3e-72
Identities = 132/297 (44%), Positives = 201/297 (67%), Gaps = 5/297 (1%)
Query: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
+E FQ + +I EGTYGVVY+A++K T E+VALK+++++ E EG P T++REI+ + + H
Sbjct: 410 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 469
Query: 61 PNIVKLLDVIHTEN--KLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFC 118
PNIV + +++ N K+Y+V ++ DLK M+ +P +K+ + QLL+G+
Sbjct: 470 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE-VKTLMIQLLRGVKHL 528
Query: 119 HSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCK 178
H + +LHRDLK NLL++ G +K+ DFGLAR +G P++ YT VVT WYRAPE+LLG K
Sbjct: 529 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAK 588
Query: 179 YYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKP 238
YSTAVD+WS+GCIF E++T++ LFPG+SEIDQ+ ++F+ LGTP E +WPG + +P K
Sbjct: 589 EYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKK 648
Query: 239 -SFPKWARQDFSKVVPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPV 293
+F + + K L + G L+++ L Y P +RISA+ L H +F++ P+
Sbjct: 649 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPI 705
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 268 bits (686), Expect = 3e-72
Identities = 132/297 (44%), Positives = 201/297 (67%), Gaps = 5/297 (1%)
Query: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
+E FQ + +I EGTYGVVY+A++K T E+VALK+++++ E EG P T++REI+ + + H
Sbjct: 420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 479
Query: 61 PNIVKLLDVIHTEN--KLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFC 118
PNIV + +++ N K+Y+V ++ DLK M+ +P +K+ + QLL+G+
Sbjct: 480 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE-VKTLMIQLLRGVKHL 538
Query: 119 HSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCK 178
H + +LHRDLK NLL++ G +K+ DFGLAR +G P++ YT VVT WYRAPE+LLG K
Sbjct: 539 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAK 598
Query: 179 YYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKP 238
YSTAVD+WS+GCIF E++T++ LFPG+SEIDQ+ ++F+ LGTP E +WPG + +P K
Sbjct: 599 EYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKK 658
Query: 239 -SFPKWARQDFSKVVPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPV 293
+F + + K L + G L+++ L Y P +RISA+ L H +F++ P+
Sbjct: 659 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPI 715
>gi|223718134 cyclin-dependent kinase 6 [Homo sapiens]
Length = 326
Score = 268 bits (685), Expect = 4e-72
Identities = 145/299 (48%), Positives = 198/299 (66%), Gaps = 13/299 (4%)
Query: 2 ENFQKVEKIGEGTYGVVYKARN-KLTGEVVALKKIRLDTETEGVPSTAIREISLLKELN- 59
+ ++ V +IGEG YG V+KAR+ K G VALK++R+ T EG+P + IRE+++L+ L
Sbjct: 11 QQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLET 70
Query: 60 --HPNIVKLLDVIHT-----ENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLL 112
HPN+V+L DV E KL LVFE + QDL ++D G+P IK +FQLL
Sbjct: 71 FEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLL 130
Query: 113 QGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPE 172
+GL F HSHRV+HRDLKPQN+L+ + G IKLADFGLAR + + T VVTLWYRAPE
Sbjct: 131 RGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQM-ALTSVVVTLWYRAPE 189
Query: 173 ILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTS 232
+LL Y+T VD+WS+GCIFAEM R+ LF G S++DQL +I +G P E WP +
Sbjct: 190 VLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVA 248
Query: 233 MPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK 291
+P + +F + Q K V +DE G+ LL + L ++P KRISA +AL+HP+FQD+ +
Sbjct: 249 LP--RQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLER 305
>gi|4502741 cyclin-dependent kinase 6 [Homo sapiens]
Length = 326
Score = 268 bits (685), Expect = 4e-72
Identities = 145/299 (48%), Positives = 198/299 (66%), Gaps = 13/299 (4%)
Query: 2 ENFQKVEKIGEGTYGVVYKARN-KLTGEVVALKKIRLDTETEGVPSTAIREISLLKELN- 59
+ ++ V +IGEG YG V+KAR+ K G VALK++R+ T EG+P + IRE+++L+ L
Sbjct: 11 QQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLET 70
Query: 60 --HPNIVKLLDVIHT-----ENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLL 112
HPN+V+L DV E KL LVFE + QDL ++D G+P IK +FQLL
Sbjct: 71 FEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLL 130
Query: 113 QGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPE 172
+GL F HSHRV+HRDLKPQN+L+ + G IKLADFGLAR + + T VVTLWYRAPE
Sbjct: 131 RGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQM-ALTSVVVTLWYRAPE 189
Query: 173 ILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTS 232
+LL Y+T VD+WS+GCIFAEM R+ LF G S++DQL +I +G P E WP +
Sbjct: 190 VLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVA 248
Query: 233 MPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK 291
+P + +F + Q K V +DE G+ LL + L ++P KRISA +AL+HP+FQD+ +
Sbjct: 249 LP--RQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLER 305
>gi|4502743 cyclin-dependent kinase 7 [Homo sapiens]
Length = 346
Score = 266 bits (679), Expect = 2e-71
Identities = 134/300 (44%), Positives = 194/300 (64%), Gaps = 5/300 (1%)
Query: 2 ENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETE---GVPSTAIREISLLKEL 58
+ ++K++ +GEG + VYKAR+K T ++VA+KKI+L +E G+ TA+REI LL+EL
Sbjct: 10 KRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
Query: 59 NHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFC 118
+HPNI+ LLD ++ + LVF+F+ DL+ + ++L P IK+Y+ LQGL +
Sbjct: 70 SHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSH-IKAYMLMTLQGLEYL 128
Query: 119 HSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCK 178
H H +LHRDLKP NLL++ G +KLADFGLA++FG P R YTH+VVT WYRAPE+L G +
Sbjct: 129 HQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGAR 188
Query: 179 YYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKP 238
Y VD+W++GCI AE++ R PGDS++DQL RIF TLGTP E WP + S+PDY
Sbjct: 189 MYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDY-V 247
Query: 239 SFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL 298
+F + + +D L+ + ++P RI+A AL +F + P P +L
Sbjct: 248 TFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQL 307
>gi|21040235 PFTAIRE protein kinase 2 [Homo sapiens]
Length = 384
Score = 262 bits (669), Expect = 3e-70
Identities = 143/288 (49%), Positives = 188/288 (65%), Gaps = 6/288 (2%)
Query: 3 NFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPN 62
++ +EK+GEG+Y VYK +++ G++VALK I ++ E EGVP TAIRE SLLK L H N
Sbjct: 51 SYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAE-EGVPFTAIREASLLKGLKHAN 109
Query: 63 IVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHR 122
IV L D+IHT+ L VFE++H DL ++M G+ ++ ++FQLL+GLA+ H
Sbjct: 110 IVLLHDIIHTKETLTFVFEYMHTDLAQYMSQHP-GGLHPHNVRLFMFQLLRGLAYIHHQH 168
Query: 123 VLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYST 182
VLHRDLKPQNLLI+ G +KLADFGLARA +P +TY+ EVVTLWYR P+ LLG YS+
Sbjct: 169 VLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSS 228
Query: 183 AVDIWSLGCIFAEMVTRRALFPGDSEI-DQLFRIFRTLGTPDEVVWPGVTSMPDYKPS-F 240
+DIW GCIF EM + LFPG S I +QL +I+ LG P E WPGV+ +P+Y P F
Sbjct: 229 ELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWF 288
Query: 241 PKWARQDFSKVVPPLDE--DGRSLLSQMLHYDPNKRISAKAALAHPFF 286
P + V L + L SQML P R+SA+ AL H +F
Sbjct: 289 PLPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEALVHDYF 336
>gi|148596926 cyclin-dependent kinase 10 isoform a [Homo sapiens]
Length = 360
Score = 258 bits (659), Expect = 4e-69
Identities = 137/302 (45%), Positives = 198/302 (65%), Gaps = 16/302 (5%)
Query: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
++ F+K+ +IGEGTYG+VY+AR+ T E+VALKK+R+D E +G+P +++REI+LL L H
Sbjct: 36 VKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRH 95
Query: 61 PNIVKLLDVI---HTENKLYLVFEFLHQDLKKFMDASALTGIPLPL----IKSYLFQLLQ 113
PNIV+L +V+ H E+ ++LV + QDL AS L +P P +K + Q+L+
Sbjct: 96 PNIVELKEVVVGNHLES-IFLVMGYCEQDL-----ASLLENMPTPFSEAQVKCIVLQVLR 149
Query: 114 GLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEI 173
GL + H + ++HRDLK NLL+ +G +K ADFGLARA+GVPV+ T +VVTLWYRAPE+
Sbjct: 150 GLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPEL 209
Query: 174 LLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSM 233
LLG +T++D+W++GCI AE++ R L PG SEI Q+ I + LGTP E +WPG + +
Sbjct: 210 LLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKL 269
Query: 234 PDY-KPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKP 292
P + S K + P L E G LL + YDP KR +A L +F++ KP
Sbjct: 270 PLVGQYSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKE--KP 327
Query: 293 VP 294
+P
Sbjct: 328 LP 329
>gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens]
Length = 346
Score = 244 bits (624), Expect = 5e-65
Identities = 130/297 (43%), Positives = 187/297 (62%), Gaps = 6/297 (2%)
Query: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKEL-N 59
M+ + + +IGEG +G+V+KA++ TGE+VALKK+ L +G P+ A+REI L+E+ +
Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED 60
Query: 60 HPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCH 119
+ +V+L V L FEF+ DL + + A + +KSYL LL+G+AFCH
Sbjct: 61 NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVV-RHAQRPLAQAQVKSYLQMLLKGVAFCH 119
Query: 120 SHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVP-VRTYTHEVVTLWYRAPEILLGCK 178
++ ++HRDLKP NLLI+ G +K+ADFGLAR F R YTH+V T WYRAPE+L G +
Sbjct: 120 ANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGAR 179
Query: 179 YYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDY-K 237
Y VD+WS+GCI E++ LFPG ++I+QL + R LGTP+ VWP +T +PDY K
Sbjct: 180 QYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNK 239
Query: 238 PSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP 294
SF + +V+P + LL Q L Y P++RI+A AL H +F T P+P
Sbjct: 240 ISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYF--FTAPLP 294
>gi|4502735 cyclin-dependent kinase 4 [Homo sapiens]
Length = 303
Score = 243 bits (620), Expect = 1e-64
Identities = 134/293 (45%), Positives = 189/293 (64%), Gaps = 15/293 (5%)
Query: 4 FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEG---VPSTAIREISLLKELN- 59
++ V +IG G YG VYKAR+ +G VALK +R+ G +P + +RE++LL+ L
Sbjct: 6 YEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRRLEA 65
Query: 60 --HPNIVKLLDVIHT-----ENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLL 112
HPN+V+L+DV T E K+ LVFE + QDL+ ++D + G+P IK + Q L
Sbjct: 66 FEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFL 125
Query: 113 QGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPE 172
+GL F H++ ++HRDLKP+N+L+ + G +KLADFGLAR + + T VVTLWYRAPE
Sbjct: 126 RGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQM-ALTPVVVTLWYRAPE 184
Query: 173 ILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTS 232
+LL Y+T VD+WS+GCIFAEM R+ LF G+SE DQL +IF +G P E WP S
Sbjct: 185 VLLQ-STYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPRDVS 243
Query: 233 MPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPF 285
+P + +FP + VVP ++E G LL +ML ++P+KRISA AL H +
Sbjct: 244 LP--RGAFPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSY 294
>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
[Homo sapiens]
Length = 1481
Score = 237 bits (605), Expect = 8e-63
Identities = 131/305 (42%), Positives = 187/305 (61%), Gaps = 21/305 (6%)
Query: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
++ F + IGEGTYG VYKA++K TGE+VALKK+RLD E EG P TAIREI +L++L H
Sbjct: 724 VDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIH 783
Query: 61 PNIVKLLDVI----------HTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQ 110
++V + +++ + YLVFE++ DL ++ S L IKS++ Q
Sbjct: 784 RSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLE-SGLVHFSEDHIKSFMKQ 842
Query: 111 LLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPV-RTYTHEVVTLWYR 169
L++GL +CH LHRD+K N+L+N G IKLADFGLAR + R YT++V+TLWYR
Sbjct: 843 LMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYR 902
Query: 170 APEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPG 229
PE+LLG + Y+ A+D+WS GCI E+ T++ +F + E+ QL I R G+P VWP
Sbjct: 903 PPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPD 962
Query: 230 VTSMPDY-----KPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHP 284
V +P + K + + R++FS +P D LL ML DP+KR +A+ L
Sbjct: 963 VIKLPYFNTMKPKKQYRRRLREEFS-FIPSAALD---LLDHMLTLDPSKRCTAEQTLQSD 1018
Query: 285 FFQDV 289
F +DV
Sbjct: 1019 FLKDV 1023
>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
[Homo sapiens]
Length = 1490
Score = 237 bits (605), Expect = 8e-63
Identities = 131/305 (42%), Positives = 187/305 (61%), Gaps = 21/305 (6%)
Query: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
++ F + IGEGTYG VYKA++K TGE+VALKK+RLD E EG P TAIREI +L++L H
Sbjct: 724 VDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIH 783
Query: 61 PNIVKLLDVI----------HTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQ 110
++V + +++ + YLVFE++ DL ++ S L IKS++ Q
Sbjct: 784 RSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLE-SGLVHFSEDHIKSFMKQ 842
Query: 111 LLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPV-RTYTHEVVTLWYR 169
L++GL +CH LHRD+K N+L+N G IKLADFGLAR + R YT++V+TLWYR
Sbjct: 843 LMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYR 902
Query: 170 APEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPG 229
PE+LLG + Y+ A+D+WS GCI E+ T++ +F + E+ QL I R G+P VWP
Sbjct: 903 PPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPD 962
Query: 230 VTSMPDY-----KPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHP 284
V +P + K + + R++FS +P D LL ML DP+KR +A+ L
Sbjct: 963 VIKLPYFNTMKPKKQYRRRLREEFS-FIPSAALD---LLDHMLTLDPSKRCTAEQTLQSD 1018
Query: 285 FFQDV 289
F +DV
Sbjct: 1019 FLKDV 1023
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.140 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,175,862
Number of Sequences: 37866
Number of extensions: 484698
Number of successful extensions: 3578
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 750
Number of HSP's successfully gapped in prelim test: 44
Number of HSP's that attempted gapping in prelim test: 978
Number of HSP's gapped (non-prelim): 968
length of query: 298
length of database: 18,247,518
effective HSP length: 102
effective length of query: 196
effective length of database: 14,385,186
effective search space: 2819496456
effective search space used: 2819496456
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.