Guide to the Human Genome
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Name: CDK4 Sequence: fasta or formatted (303aa) NCBI GI: 4502735
Description:

cyclin-dependent kinase 4

Referenced in:

Cyclins and Related Functions

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.3         22           1
 C cysteine            1.3          4           1
 D aspartate           5.6         17           2
 E glutamate           6.3         19           2
 F phenylalanine       4.3         13           1
 G glycine             7.9         24           7
 H histidine           3.0          9           1
 I isoleucine          3.6         11           1
 K lysine              3.6         11           1
 L leucine            10.9         33           3
 M methionine          2.6          8           1
 N asparagine          2.3          7           1
 P proline             8.3         25           3
 Q glutamine           2.6          8           1
 R arginine            7.6         23           2
 S serine              5.0         15           1
 T threonine           5.0         15           1
 V valine              8.9         27           3
 W tryptophan          1.0          3           1
 Y tyrosine            3.0          9           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   cyclin-dependent kinase 4 
CDK6                  0.663   cyclin-dependent kinase 6 
CDK6                  0.663   cyclin-dependent kinase 6 
CDK3                  0.392   cyclin-dependent kinase 3 
CDK2                  0.367   cyclin-dependent kinase 2 isoform 1 
CDC2                  0.347   cell division cycle 2 isoform 1 
CDC2                  0.343   cell division cycle 2 isoform 3 
CDK5                  0.335   cyclin-dependent kinase 5 
CDK10                 0.310   cyclin-dependent kinase 10 isoform a 
CDC2L1                0.305   cell division cycle 2-like 1 (PITSLRE proteins) isof...
CDC2L1                0.305   cell division cycle 2-like 1 (PITSLRE proteins) isof...
CDC2L1                0.305   cell division cycle 2-like 1 (PITSLRE proteins) isof...
CDC2L1                0.305   cell division cycle 2-like 1 (PITSLRE proteins) isof...
CDC2L1                0.305   cell division cycle 2-like 1 (PITSLRE proteins) isof...
CDC2L1                0.305   cell division cycle 2-like 1 (PITSLRE proteins) isof...
CDC2L2                0.305   cell division cycle 2-like 2 isoform 4 
CDC2L2                0.305   cell division cycle 2-like 2 isoform 1 
PCTK3                 0.301   PCTAIRE protein kinase 3 isoform a 
PCTK3                 0.301   PCTAIRE protein kinase 3 isoform b 
PCTK3                 0.301   PCTAIRE protein kinase 3 isoform b 
PCTK2                 0.301   PCTAIRE protein kinase 2 
PCTK1                 0.291   PCTAIRE protein kinase 1 isoform 2 
PCTK1                 0.291   PCTAIRE protein kinase 1 isoform 1 
PFTK1                 0.281   PFTAIRE protein kinase 1 
PFTK2                 0.279   PFTAIRE protein kinase 2 
CDK7                  0.273   cyclin-dependent kinase 7 
CDK10                 0.266   cyclin-dependent kinase 10 isoform d 
CDK10                 0.266   cyclin-dependent kinase 10 isoform b 
MAK                   0.263   male germ cell-associated kinase 
ICK                   0.261   intestinal cell kinase 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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