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Search of human proteins with 16933542
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo
sapiens]
(2355 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens] 4904 0.0
gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens] 4838 0.0
gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens] 3543 0.0
gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens] 3522 0.0
gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens] 3002 0.0
gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens] 3002 0.0
gi|47132547 fibronectin 1 isoform 7 preproprotein [Homo sapiens] 1440 0.0
gi|93141047 collagen, type XII, alpha 1 long isoform precursor [... 383 e-105
gi|153946395 tenascin C precursor [Homo sapiens] 360 7e-99
gi|157384973 tenascin R [Homo sapiens] 353 1e-96
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] 327 1e-88
gi|62988324 tenascin N [Homo sapiens] 315 4e-85
gi|93141049 collagen, type XII, alpha 1 short isoform precursor ... 296 2e-79
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 235 4e-61
gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens] 209 3e-53
gi|222352127 sidekick 2 [Homo sapiens] 164 7e-40
gi|157952215 protein tyrosine phosphatase, receptor type, B isof... 164 7e-40
gi|157952213 protein tyrosine phosphatase, receptor type, B isof... 164 7e-40
gi|112734845 collagen, type XX, alpha 1 [Homo sapiens] 155 4e-37
gi|110349719 titin isoform N2-A [Homo sapiens] 154 1e-36
gi|110349717 titin isoform novex-2 [Homo sapiens] 154 1e-36
gi|110349713 titin isoform novex-1 [Homo sapiens] 154 1e-36
gi|110349715 titin isoform N2-B [Homo sapiens] 154 1e-36
gi|109633039 protein tyrosine phosphatase, receptor type, F isof... 153 2e-36
gi|119220552 sidekick 1 [Homo sapiens] 152 5e-36
gi|18860892 protein tyrosine phosphatase, receptor type, D isofo... 149 2e-35
gi|109633041 protein tyrosine phosphatase, receptor type, F isof... 147 1e-34
gi|20665034 tenascin XB isoform 2 [Homo sapiens] 147 2e-34
gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens] 146 3e-34
gi|11342666 matrix metalloproteinase 2 isoform a preproprotein [... 146 3e-34
>gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens]
Length = 2355
Score = 4904 bits (12721), Expect = 0.0
Identities = 2355/2355 (100%), Positives = 2355/2355 (100%)
Query: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
Query: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
Query: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
Query: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
Query: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
Query: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
Query: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
Query: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
Query: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
Query: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
Query: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
Query: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
Query: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
Query: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
Query: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
Query: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
Query: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
Query: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD
Sbjct: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
Query: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA
Sbjct: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
Query: 1381 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440
PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL
Sbjct: 1381 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440
Query: 1441 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500
IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK
Sbjct: 1441 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500
Query: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1560
STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV
Sbjct: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1560
Query: 1561 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE
Sbjct: 1561 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
Query: 1621 SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1680
SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP
Sbjct: 1621 SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1680
Query: 1681 DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSA 1740
DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSA
Sbjct: 1681 DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSA 1740
Query: 1741 QWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT 1800
QWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT
Sbjct: 1741 QWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT 1800
Query: 1801 SRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT 1860
SRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT
Sbjct: 1801 SRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT 1860
Query: 1861 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLL 1920
IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLL
Sbjct: 1861 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLL 1920
Query: 1921 VSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQ 1980
VSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQ
Sbjct: 1921 VSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQ 1980
Query: 1981 KSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTS 2040
KSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTS
Sbjct: 1981 KSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTS 2040
Query: 2041 GQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSE 2100
GQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSE
Sbjct: 2041 GQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSE 2100
Query: 2101 YIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVG 2160
YIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVG
Sbjct: 2101 YIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVG 2160
Query: 2161 NSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWC 2220
NSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWC
Sbjct: 2161 NSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWC 2220
Query: 2221 HDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKE 2280
HDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKE
Sbjct: 2221 HDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKE 2280
Query: 2281 YLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIEC 2340
YLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIEC
Sbjct: 2281 YLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIEC 2340
Query: 2341 FMPLDVQADREDSRE 2355
FMPLDVQADREDSRE
Sbjct: 2341 FMPLDVQADREDSRE 2355
>gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens]
Length = 2330
Score = 4838 bits (12549), Expect = 0.0
Identities = 2330/2355 (98%), Positives = 2330/2355 (98%), Gaps = 25/2355 (1%)
Query: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
Query: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
Query: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
Query: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
Query: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
Query: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
Query: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
Query: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
Query: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
Query: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
Query: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
Query: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
Query: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
Query: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
Query: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
Query: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
Query: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
Query: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD
Sbjct: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
Query: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA
Sbjct: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
Query: 1381 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440
PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL
Sbjct: 1381 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440
Query: 1441 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500
IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK
Sbjct: 1441 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500
Query: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1560
STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV
Sbjct: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1560
Query: 1561 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE
Sbjct: 1561 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
Query: 1621 SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1680
SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP
Sbjct: 1621 SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1680
Query: 1681 DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSA 1740
DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSA
Sbjct: 1681 DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSA 1740
Query: 1741 QWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT 1800
QWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT
Sbjct: 1741 QWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT 1800
Query: 1801 SRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT 1860
SRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT
Sbjct: 1801 SRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT 1860
Query: 1861 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLL 1920
IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLL
Sbjct: 1861 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLL 1920
Query: 1921 VSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQ 1980
VSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQ
Sbjct: 1921 VSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQ 1980
Query: 1981 KSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTS 2040
KSEPLIGRKK TVQKTPFVTHPGYDTGNGIQLPGTS
Sbjct: 1981 KSEPLIGRKK-------------------------TVQKTPFVTHPGYDTGNGIQLPGTS 2015
Query: 2041 GQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSE 2100
GQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSE
Sbjct: 2016 GQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSE 2075
Query: 2101 YIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVG 2160
YIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVG
Sbjct: 2076 YIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVG 2135
Query: 2161 NSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWC 2220
NSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWC
Sbjct: 2136 NSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWC 2195
Query: 2221 HDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKE 2280
HDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKE
Sbjct: 2196 HDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKE 2255
Query: 2281 YLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIEC 2340
YLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIEC
Sbjct: 2256 YLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIEC 2315
Query: 2341 FMPLDVQADREDSRE 2355
FMPLDVQADREDSRE
Sbjct: 2316 FMPLDVQADREDSRE 2330
>gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens]
Length = 2176
Score = 3543 bits (9186), Expect = 0.0
Identities = 1737/1986 (87%), Positives = 1793/1986 (90%), Gaps = 21/1986 (1%)
Query: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
Query: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
Query: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
Query: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
Query: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
Query: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
Query: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
Query: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
Query: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
Query: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
Query: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
Query: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
Query: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
Query: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
Query: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
Query: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
Query: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
Query: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD
Sbjct: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
Query: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA
Sbjct: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
Query: 1381 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440
PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL
Sbjct: 1381 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440
Query: 1441 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500
IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK
Sbjct: 1441 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500
Query: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1560
STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV
Sbjct: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1560
Query: 1561 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE
Sbjct: 1561 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
Query: 1621 SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPE--DGIHELFP 1678
SQPLVQTAVT I P L FT V S+ W P Q++ YRV + E + E+
Sbjct: 1621 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1680
Query: 1679 APDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA--IPAPTDLKFTQVTPT 1736
APD + + GL ++Y VSV AL D + S+P G +T + P + T T T
Sbjct: 1681 APD--SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATET 1738
Query: 1737 SLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1796
+++ W +TG++V P P++ + PD S ++GL T Y++ +Y L
Sbjct: 1739 TITISWRTKTETITGFQVDAVPANGQTPIQR-TIKPDVRSYTITGLQPGTDYKIYLYTLN 1797
Query: 1797 DTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVD-AVPANGQT 1855
D S P V+ + P R T ++ +SW+ ITG+ + P +
Sbjct: 1798 DNARSSPV--VIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPR 1855
Query: 1856 PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATT 1915
+ +P V TITGL+PGT+Y IY+ L +N +S P++ T +A S TT
Sbjct: 1856 EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEALSQ-----TT 1910
Query: 1916 PNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 1975
+SW P + + YII G+ + R T AT+TGL G Y I V A
Sbjct: 1911 -----ISWAPFQ-DTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEA 1964
Query: 1976 LKNNQK 1981
LK+ Q+
Sbjct: 1965 LKDQQR 1970
Score = 1053 bits (2724), Expect = 0.0
Identities = 639/1585 (40%), Positives = 860/1585 (54%), Gaps = 94/1585 (5%)
Query: 829 VRWSRPQ-APITGYRIVYSPSVE-GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEE- 885
++W+ PQ + I+ Y + + P G E +P NS T+ L+PGV Y + ++++
Sbjct: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
Query: 886 -NQESTPVVIQQETTGTPRSDTVPSPRDLQF----------VEVTDVKVTIMWTPPESAV 934
+QE T +T TP + + F E+T + W V
Sbjct: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
Query: 935 TGYRVDVIPVNLPGEHGQRLPI-SRNTFAEVTGLSPGVTYYFKVFAVSH-GRESKPLTAQ 992
+G+RV+ ++ G+ Q L + S T + L PG Y V+ +S G +S L+
Sbjct: 748 SGFRVEY-ELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTS 806
Query: 993 QTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYP 1052
QTT DAP + D++++VRW+ P+A ITGYR+ + G + N+ + +
Sbjct: 807 QTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVT 866
Query: 1053 LRNLQPASEYTVSLVAIKGNQES-PKATGVFTTLQPGSSIPPYN-----TEVTETTIVIT 1106
L +LQP +Y +++ A++ NQES P TT P S P EVT+ + I
Sbjct: 867 LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
Query: 1107 WTPAPRI--GFKLGVRPSQ--GGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQER 1162
WTP G+++ V P G R S + V+GL+PGV Y + + + G+E
Sbjct: 927 WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE- 985
Query: 1163 DAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTP--DITGYRITTTPTNGQQGNS 1220
P+ + T L PTNL D+ VL V W T P ITGYR+T T ++G
Sbjct: 986 SKPLTAQQTTKLDAPTNLQFVNETDSTVL-VRW---TPPRAQITGYRLTVGLT--RRGQP 1039
Query: 1221 LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVP----PPTDLRFT 1276
+ V S NL P EY VS+ +K ++ES + P PP + T
Sbjct: 1040 RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN---T 1096
Query: 1277 NIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVV 1336
+ T+ +TW P P I F + P + E A ++ ++V++ L PG EYV
Sbjct: 1097 EVTETTIVITWTPAPRI---GFKLGVRPSQGGE--APREVTSDSGSIVVSGLTPGVEYVY 1151
Query: 1337 SVSSVYE-QHESTPLRGRQKTGLDSPTGIDF-SDITANSFTVHWIAPRAT---ITGYRIR 1391
++ + + Q P+ + T L PT + ++ TV W R+T ITGYRI
Sbjct: 1152 TIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW--ERSTTPDITGYRIT 1209
Query: 1392 HHPEHFS-GRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV 1450
P + G E+ V ++S T NL+PG EY VS+ + +ES +
Sbjct: 1210 TTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPP 1269
Query: 1451 PRDLEVVAATPTSLLISW-DAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLK 1509
P DL P ++ ++W P++ + + + Y V E ++ S + ++ L
Sbjct: 1270 PTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL 1329
Query: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPV 1569
PG +Y ++V +V + +S P+ +T +D P+ + +D+ NS +V W+ + +
Sbjct: 1330 PGTEYVVSVSSVYEQHEST----PLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATI 1385
Query: 1570 TGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAV 1629
TGYR+ P++ G + + +T+ L P EYVVS+ A N ES L+
Sbjct: 1386 TGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS 1445
Query: 1630 TNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSP--EDGIHELFPAPDGEEDTA 1687
T D P+ L S+ I+W++P V YR+TY + E F P G + TA
Sbjct: 1446 TVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQE-FTVP-GSKSTA 1503
Query: 1688 ELQGLRPGSEYTVSVVAL----HDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWT 1743
+ GL+PG +YT++V A+ S+P+ T I P+ ++ T V S+S +W
Sbjct: 1504 TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL 1563
Query: 1744 PPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP 1803
P + +TGYRV TPK GP K PD + + + GL +Y VSVYA + S+P
Sbjct: 1564 PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
Query: 1804 AQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQR-TIK 1862
V T + + P + T T T+++ W +TG++V P P++ +
Sbjct: 1624 L--VQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLA 1681
Query: 1863 PDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV--VIDASTAIDAPSNLRFLATTPNSLL 1920
PD S ++GL T Y++ +Y L D S P V+ + P R T ++
Sbjct: 1682 PDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTIT 1741
Query: 1921 VSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQ 1980
+SW+ ITG+ + P + + +P V TITGL+PGT+Y IY+ L +N
Sbjct: 1742 ISWRTKTETITGFQVD-AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1800
Query: 1981 KSEPLIGRKKT-----DELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTH---PGYDTGN 2032
+S P++ T L L T P+ L + P + T ++ PG
Sbjct: 1801 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQ----PPRARITGYIIKYEKPGSPPRE 1856
Query: 2033 GIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPY--PPNVGQEALSQTTI 2090
+ P +P V + I T A + P GQEALSQTTI
Sbjct: 1857 VVPRP-----RPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEALSQTTI 1911
Query: 2091 SWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRH 2150
SWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRH
Sbjct: 1912 SWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRH 1971
Query: 2151 KVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSG 2210
KVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSG
Sbjct: 1972 KVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSG 2031
Query: 2211 HFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKT 2270
HFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKT
Sbjct: 2032 HFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKT 2091
Query: 2271 YHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRT 2330
YHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRT
Sbjct: 2092 YHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRT 2151
Query: 2331 NTNVNCPIECFMPLDVQADREDSRE 2355
NTNVNCPIECFMPLDVQADREDSRE
Sbjct: 2152 NTNVNCPIECFMPLDVQADREDSRE 2176
Score = 929 bits (2401), Expect = 0.0
Identities = 613/1524 (40%), Positives = 819/1524 (53%), Gaps = 131/1524 (8%)
Query: 768 LPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAP------------- 814
+P S I L PG Y + I + G Q + TT+ P
Sbjct: 659 IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
Query: 815 -----PDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTE-LNLPETANSVTLS 868
+V ++ +S VV W ++G+R+ Y S EG + L+LP TA SV +
Sbjct: 719 SPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778
Query: 869 DLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWT 928
DL PG +Y + +Y + E+ E + ++ +TT +P D +V D + + W+
Sbjct: 779 DLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPD------APPDPTVDQVDDTSIVVRWS 832
Query: 929 PPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP 988
P++ +TGYR+ P LP + N+ ++ L PGV Y ++AV +ES P
Sbjct: 833 RPQAPITGYRIVYSPSVEGSSTELNLPETANSVT-LSDLQPGVQYNITIYAVEENQESTP 891
Query: 989 LTAQQTTK-------LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQ 1041
+ QQ T + +P +LQFV TD V + WTPP + +TGYR+ V P +
Sbjct: 892 VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDV--IPVNLPGE 949
Query: 1042 YNVGPSVSKYP---LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEV 1098
+ +S+ + L P Y + A+ +ES T TT + + E
Sbjct: 950 HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE- 1008
Query: 1099 TETTIVITWTP--APRIGFKLGVRPSQGGEAPRE--VTSDSGSIVVSGLTPGVEYVYTIQ 1154
T++T+++ WTP A G++L V ++ G+ PR+ V + L P EY ++
Sbjct: 1009 TDSTVLVRWTPPRAQITGYRLTVGLTRRGQ-PRQYNVGPSVSKYPLRNLQPASEYTVSLV 1067
Query: 1155 VLRDGQERDAPIVNKVVTPLSPPTNL---HLEANPDTGVLTVSWERSTTPDITGYRITTT 1211
++ QE +P V T L P +++ + E T V+T W T G+++
Sbjct: 1068 AIKGNQE--SPKATGVFTTLQPGSSIPPYNTEVTETTIVIT--W---TPAPRIGFKLGVR 1120
Query: 1212 PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE-SVPISDTIIPAVPPP 1270
P+ QG V +D S L+PG+EY ++ ++D +E PI + ++ + PP
Sbjct: 1121 PS---QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPP 1177
Query: 1271 TDLRFTNIGPDT--MRVTWAPPPSIDLTNFLVRYSPVKNEE-DVAELSISPSDNAVVLTN 1327
T+L PDT + V+W + D+T + + +P ++ + E + ++ N
Sbjct: 1178 TNLHL-EANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDN 1236
Query: 1328 LLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRAT-IT 1386
L PG EY VSV +V + ES P+ + PT + F++I ++ V W P + +T
Sbjct: 1237 LSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLT 1296
Query: 1387 GYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQST 1446
+ +R+ P E + S N++ LTNL PGTEYVVS+ ++ + ES L G+Q T
Sbjct: 1297 NFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT 1356
Query: 1447 VSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATIS 1506
D P ++ T S + W AP T+ YRI + + +E VP S+++ T++
Sbjct: 1357 GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT 1416
Query: 1507 GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSS 1566
L PG +Y +++ A+ GR +SP S T D P ++V S+ + W +
Sbjct: 1417 NLTPGTEYVVSIVALNGREESPLLIGQQS----TVSDVPRDLEVVAATPTSLLISWDAPA 1472
Query: 1567 SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES----Q 1622
V YR+T G P + T ++ TI GL+P V+Y ++VYA G+S +
Sbjct: 1473 VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSK 1532
Query: 1623 PLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDG 1682
P+ T ID+P + TDV +SI + W V+ YRVT ++P++G G
Sbjct: 1533 PISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVT-TTPKNGPGPTKTKTAG 1591
Query: 1683 EEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQ 1741
+ T ++GL+P EY VSV A + ESQPL+ T T IPAPTDLKFTQVTPTSLSAQ
Sbjct: 1592 PDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQ 1651
Query: 1742 WTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1801
WTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS
Sbjct: 1652 WTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1711
Query: 1802 RPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTI 1861
RPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTI
Sbjct: 1712 RPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTI 1771
Query: 1862 KPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLV 1921
KPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLV
Sbjct: 1772 KPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLV 1831
Query: 1922 SWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 1981
SWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK
Sbjct: 1832 SWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 1891
Query: 1982 SEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPF--------VTHPGYDTGNG 2033
SEPLIGRKKT G E L +T+ PF HP
Sbjct: 1892 SEPLIGRKKT---------------GQEALS-QTTISWAPFQDTSEYIISCHPVGTDEEP 1935
Query: 2034 IQ--LPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVG---QEALSQT 2088
+Q +PGTS G RH+ R VG E L+Q
Sbjct: 1936 LQFRVPGTSTSATLTG----LTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQ- 1990
Query: 2089 TISWAPFQDT--SEYIISCHPVGTDEE-------PLQFRVPGTSTSATLTGLTR-----G 2134
P D+ Y +S + VG + E L + G + +R G
Sbjct: 1991 -----PTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNG 2045
Query: 2135 ATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMS 2194
Y I E Q + +GN E P + +C+D H VG++W++
Sbjct: 2046 VNYK-IGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYH--VGEQWQK-E 2101
Query: 2195 ESGFKLLCQCLGFGSGHFRCDSSR 2218
G C C G G +RCD+ R
Sbjct: 2102 YLGAICSCTCFG-GQRGWRCDNCR 2124
Score = 462 bits (1189), Expect = e-129
Identities = 346/1230 (28%), Positives = 564/1230 (45%), Gaps = 79/1230 (6%)
Query: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
++W+ PQ + I+ Y + + P G E +P NS T+ L+PGV Y + ++++
Sbjct: 829 VRWSRPQ-APITGYRIVYSPSVE-GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEE- 885
Query: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
+QE T +T TP + + F E+T + W V
Sbjct: 886 -NQESTPVVIQQETTGTPRSDTVPSPRDLQF----------VEVTDVKVTIMWTPPESAV 934
Query: 748 SGFRVEY-ELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTS 806
+G+RV+ ++ G+ Q L + S T + L PG Y V+ +S G +S L+
Sbjct: 935 TGYRVDVIPVNLPGEHGQRLPI-SRNTFAEVTGLSPGVTYYFKVFAVSH-GRESKPLTAQ 992
Query: 807 QTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVT 866
QTT DAP + D++++VRW+ P+A ITGYR+ + G + N+ + +
Sbjct: 993 QTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYP 1052
Query: 867 LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
L +LQP +Y +++ A++ NQES P TT P S P EVT+ + I
Sbjct: 1053 LRNLQPASEYTVSLVAIKGNQES-PKATGVFTTLQPGSSIPPYN-----TEVTETTIVIT 1106
Query: 927 WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE- 985
WTP G+++ V P G R S + V+GL+PGV Y + + + G+E
Sbjct: 1107 WTPAPRI--GFKLGVRPSQ--GGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQER 1162
Query: 986 SKPLTAQQTTKLDAPTNLQFVNETDSTVL-VRW---TPPRAQITGYRLTVGLT--RRGQP 1039
P+ + T L PTNL D+ VL V W T P ITGYR+T T ++G
Sbjct: 1163 DAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTP--DITGYRITTTPTNGQQGNS 1220
Query: 1040 RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN---T 1096
+ V S NL P EY VS+ +K ++ES + P PP + T
Sbjct: 1221 LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVP----PPTDLRFT 1276
Query: 1097 EVTETTIVITWTPAPRI---GFKLGVRPSQGGE--APREVTSDSGSIVVSGLTPGVEYVY 1151
+ T+ +TW P P I F + P + E A ++ ++V++ L PG EYV
Sbjct: 1277 NIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVV 1336
Query: 1152 TIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW--ERSTTPDITGYRIT 1209
++ + + Q P+ + T L PT + ++ TV W R+T ITGYRI
Sbjct: 1337 SVSSVYE-QHESTPLRGRQKTGLDSPTGIDF-SDITANSFTVHWIAPRAT---ITGYRIR 1391
Query: 1210 TTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPP 1269
P + G E+ V ++S T NL+PG EY VS+ + +ES +
Sbjct: 1392 HHPEHFS-GRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV 1450
Query: 1270 PTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL 1329
P DL P ++ ++W P++ + + + Y V E ++ S + ++ L
Sbjct: 1451 PRDLEVVAATPTSLLISW-DAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLK 1509
Query: 1330 PGTEYVVSVSSVYEQHEST----PLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATI 1385
PG +Y ++V +V + +S P+ +T +D P+ + +D+ NS +V W+ + +
Sbjct: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPV 1569
Query: 1386 TGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS 1445
TGYR+ P++ G + + +T+ L P EYVVS+ A N ES L+
Sbjct: 1570 TGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAV 1629
Query: 1446 TVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI 1505
T P DL+ TPTSL W P V + YR+ P++E + S+ +
Sbjct: 1630 TTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1689
Query: 1506 SGLKPGVDYTITVYAVTGRGDSPASSKPIS--INYRTEIDKPSQMQVTDVQDNSISVKWL 1563
SGL Y ++VYA+ +S+P + + P + +VTD + +I++ W
Sbjct: 1690 SGLMVATKYEVSVYALK----DTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWR 1745
Query: 1564 PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
+ +TG++V P NG P + +T PD TI GLQP +Y + +Y N + S P
Sbjct: 1746 TKTETITGFQVDAVPANGQTPIQ-RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP 1804
Query: 1624 LVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE 1683
+V A T ID P L F +S+ ++W+ P+ +++ Y + Y P E+ P P
Sbjct: 1805 VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPG 1864
Query: 1684 EDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWT 1743
A + GL PG+EYT+ V+AL ++ +S+PLIG + T A ++ T++S W
Sbjct: 1865 VTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEA--------LSQTTIS--WA 1914
Query: 1744 PPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP 1803
P + Y + P + + S+S ++GL Y + V ALKD +
Sbjct: 1915 PFQ-DTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKV 1973
Query: 1804 AQGVVTTLENVSPPRRARVTDATETTITIS 1833
+ VVT +V+ D+ T+S
Sbjct: 1974 REEVVTVGNSVNEGLNQPTDDSCFDPYTVS 2003
Score = 368 bits (945), Expect = e-101
Identities = 311/1159 (26%), Positives = 522/1159 (45%), Gaps = 87/1159 (7%)
Query: 1089 SSIPPYNTEVTET-----TIVITWT---PAPRIGFKLGVRPSQGGEAPREVTSDS--GSI 1138
SS P +TET + I W P+ + L RP +E T S
Sbjct: 607 SSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
Query: 1139 VVSGLTPGVEYV-YTIQVLRDGQER-----------DAPIVNKVVTPLSPPTNLHLEANP 1186
+ GL PGV Y I + + G + P+ + VT + P + + +
Sbjct: 667 TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
Query: 1187 DTGVLT-----VSWERSTTPDITGYRIT-TTPTNGQQGNSLEEVVHADQSSCTFDNLSPG 1240
+T VSW S + ++G+R+ G + L+ + + +S +L PG
Sbjct: 727 SVTEITASSFVVSWV-SASDTVSGFRVEYELSEEGDEPQYLD--LPSTATSVNIPDLLPG 783
Query: 1241 LEYNVSVYTVKDDKESVPI---SDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTN 1297
+Y V+VY + +D E I S T P PP D + ++ V W+ P + +T
Sbjct: 784 RKYIVNVYQISEDGEQSLILSTSQTTAPDAPP--DPTVDQVDDTSIVVRWSRPQA-PITG 840
Query: 1298 FLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG 1357
+ + YSP E EL++ + N+V L++L PG +Y +++ +V E ESTP+ +Q+T
Sbjct: 841 YRIVYSP-SVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETT 899
Query: 1358 -------LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSR 1410
+ SP + F ++T T+ W P + +TGYR+ P + G + R+P SR
Sbjct: 900 GTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQ-RLPISR 958
Query: 1411 NSIT-LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWD 1469
N+ +T L+PG Y + A++ ES L QQ+T D P +L+ V T +++L+ W
Sbjct: 959 NTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWT 1018
Query: 1470 APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1529
P + YR+T G T P +++ V S S + L+P +YT+++ A+ G +SP
Sbjct: 1019 PPRAQITGYRLTVGLTRRGQP-RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPK 1077
Query: 1530 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1589
++ + P +VT+ +I + W P+ P G+++ P G + T
Sbjct: 1078 ATGVFTTLQPGSSIPPYNTEVTET---TIVITWTPA--PRIGFKLGVRPSQGGEAPREVT 1132
Query: 1590 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ-PLVQTAVTNIDRPKGLAF-TDVDVDS 1647
+ D + + GL P VEYV ++ E P+V VT + P L + D
Sbjct: 1133 S--DSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGV 1190
Query: 1648 IKIAWE-SPQGQVSRYRVTYSSPEDGI--HELFPAPDGEEDTAELQGLRPGSEYTVSVVA 1704
+ ++WE S ++ YR+T ++P +G + L ++ + L PG EY VSV
Sbjct: 1191 LTVSWERSTTPDITGYRIT-TTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249
Query: 1705 LHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP-NVQLTGYRVRVTPKEKTG 1763
+ DD ES P+ T A+P PTDL+FT + P ++ W PP ++ LT + VR +P +
Sbjct: 1250 VKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEE 1309
Query: 1764 PMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVT 1823
+ E++++P ++VV++ L+ T+Y VSV ++ + S P +G T + P +
Sbjct: 1310 DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT--GLDSPTGIDFS 1367
Query: 1824 DATETTITISWRTKTETITGFQVDAVPAN-GQTPIQRTIKPDVRSYTITGLQPGTDYKIY 1882
D T + T+ W TITG+++ P + P + + S T+T L PGT+Y +
Sbjct: 1368 DITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVS 1427
Query: 1883 LYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPG- 1941
+ LN S ++ ST D P +L +A TP SLL+SW P + Y I Y + G
Sbjct: 1428 IVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGG 1487
Query: 1942 -SPPRE-VVPRPRPGVTEATITGLEPGTEYTIYVIALKNN----QKSEPLIGRKKTD-EL 1994
SP +E VP + + ATI+GL+PG +YTI V A+ S+P+ +T+ +
Sbjct: 1488 NSPVQEFTVPGSK---STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDK 1544
Query: 1995 PQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQ----------QP 2044
P + + + + +PS+ T + G G T+G QP
Sbjct: 1545 PSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
Query: 2045 SVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQ-DTSEYII 2103
+V + + P T + P P Q + + W P + Y +
Sbjct: 1605 TVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRV 1664
Query: 2104 SCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSV 2163
P + + S+S ++GL Y + V ALKD + + VVT +V
Sbjct: 1665 RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV 1724
Query: 2164 NEGLNQPTDDSCFDPYTVS 2182
+ D+ T+S
Sbjct: 1725 SPPRRARVTDATETTITIS 1743
Score = 126 bits (316), Expect = 3e-28
Identities = 137/535 (25%), Positives = 216/535 (40%), Gaps = 63/535 (11%)
Query: 1712 QPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQ-LTGYRVRVTPKEKTGPMKEINL 1770
QPL S++ P + T P S QW P ++ Y +R PK G KE +
Sbjct: 600 QPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATI 659
Query: 1771 APDSSSVVVSGLMVATKYEVSVYALKD-------------TLTSRPAQGVVTTLENV--S 1815
+S + GL YE + +++ T TS P T E S
Sbjct: 660 PGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFS 719
Query: 1816 P--PRRARVTDATETTITISWRTKTETITGFQVD-AVPANGQTPIQRTIKPDVRSYTITG 1872
P VT+ T ++ +SW + ++T++GF+V+ + G P + S I
Sbjct: 720 PLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPD 779
Query: 1873 LQPGTDYKIYLYTLNDNARSSPVVIDA-STAIDAPSNLRFLATTPNSLLVSWQPPRARIT 1931
L PG Y + +Y ++++ S ++ + +TA DAP + S++V W P+A IT
Sbjct: 780 LLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPIT 839
Query: 1932 GYIIKYEKP--GSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRK 1989
GY I Y GS +P VT ++ L+PG +Y I + A++ NQ+S P++ ++
Sbjct: 840 GYRIVYSPSVEGSSTELNLPETANSVT---LSDLQPGVQYNITIYAVEENQESTPVVIQQ 896
Query: 1990 KTDELPQLVTLPHP-NLHGPEILDVPSTVQKTP---FVTHPGYDTGNGIQLPGTSGQQPS 2045
+T P+ T+P P +L E+ DV T+ TP VT D + LPG GQ+
Sbjct: 897 ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDV-IPVNLPGEHGQRLP 955
Query: 2046 VGQQMIFEEHGFR---------------RTTPPTTATPIRHRPRPYPPNVGQEALSQTTI 2090
+ + E G R + P TA P E S +
Sbjct: 956 ISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLV 1015
Query: 2091 SWAPFQ-DTSEYIISCHPVGTDE--EPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQ 2147
W P + + Y ++ VG +P Q+ V + + L L + Y + + A+K
Sbjct: 1016 RWTPPRAQITGYRLT---VGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGN 1072
Query: 2148 QRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYT--VSHYAVGDEWERMSESGFKL 2200
Q V T QP S PY V+ + W GFKL
Sbjct: 1073 QESPKATGVFTT--------LQP--GSSIPPYNTEVTETTIVITWTPAPRIGFKL 1117
Score = 115 bits (287), Expect = 7e-25
Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)
Query: 2172 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2231
+++CFD YT + Y VGD +ER +S C C+G G G C + CH+ G +YKIG+
Sbjct: 94 EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
Query: 2232 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2287
W R E G M+ C CLGNGKGE+ C P C+D G +Y VGE W+K Y G +
Sbjct: 153 TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
Query: 2288 CTCFGGQRG 2296
CTC G G
Sbjct: 213 CTCLGEGSG 221
Score = 115 bits (287), Expect = 7e-25
Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)
Query: 94 EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
+++CFD YT + Y VGD +ER +S C C+G G G C + CH+ G +YKIG+
Sbjct: 1993 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2052
Query: 153 TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
W R E G M+ C CLGNGKGE+ C P C+D G +Y VGE W+K Y G +
Sbjct: 2053 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2108
Query: 213 CTCLGEGSG 221
CTC G G
Sbjct: 2109 CTCFGGQRG 2117
Score = 98.6 bits (244), Expect = 6e-20
Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)
Query: 2155 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2214
E V +GN E +P + CFD + Y VG+ WE+ + + C CLG GSG C
Sbjct: 166 ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
Query: 2215 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2260
S C+D +Y+IG+ W ++ G ++ C C GNG+GE+KC+ H
Sbjct: 226 TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
Query: 2261 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2292
A Y D G Y VG QW K CTC G
Sbjct: 286 FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
Score = 98.6 bits (244), Expect = 6e-20
Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)
Query: 166 ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
E V +GN E +P + CFD + Y VG+ WE+ + + C CLG GSG C
Sbjct: 1976 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2035
Query: 226 TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
S C+D +Y+IG+ W ++ G ++ C C GNG+GE+KC+ H
Sbjct: 2036 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2081
Query: 286 FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
A Y D G Y VG QW K CTC G
Sbjct: 2082 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2113
Score = 90.9 bits (224), Expect = 1e-17
Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)
Query: 2184 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2239
Y +GD+W++ + G + C C+G G G + C + D + + Y + + + ++ E
Sbjct: 478 YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
Query: 2240 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2296
G M++CTC G G+G +KCDP + C D G Y +G+ W+K G C C+G G
Sbjct: 538 GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
Query: 2297 WRC 2299
W C
Sbjct: 597 WHC 599
Score = 90.9 bits (224), Expect = 1e-17
Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)
Query: 478 YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
Y +GD+W++ + G + C C+G G G + C + D + + Y + + + ++ E
Sbjct: 2005 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2060
Query: 538 GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
G M++CTC G G+G +KCDP + C D G Y +G+ W+K G C C+G G
Sbjct: 2061 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2117
Query: 597 WHC 599
W C
Sbjct: 2118 WRC 2120
Score = 88.2 bits (217), Expect = 9e-17
Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)
Query: 2184 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2239
Y +GD W R E+G + L C CLG G G + C + C D+ G +Y +GE W++ +
Sbjct: 148 YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
Query: 2240 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2296
M+ CTCLG G G C D +T Y +G+ W +K+ G + C C G RG
Sbjct: 208 WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
Query: 2297 WRCD 2300
W+C+
Sbjct: 268 WKCE 271
Score = 88.2 bits (217), Expect = 9e-17
Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)
Query: 148 YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
Y +GD W R E+G + L C CLG G G + C + C D+ G +Y +GE W++ +
Sbjct: 2005 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2060
Query: 208 WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
M+ CTCLG G G C D +T Y +G+ W +K+ G + C C G RG
Sbjct: 2061 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2117
Query: 268 WKCE 271
W+C+
Sbjct: 2118 WRCD 2121
Score = 79.7 bits (195), Expect = 3e-14
Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)
Query: 2222 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2278
+ GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C + C D TY+V + +
Sbjct: 473 NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
Query: 2279 KEY-LGAICSCTCFGGQRG-WRCD 2300
K + G + +CTCFG RG W+CD
Sbjct: 533 KRHEEGHMLNCTCFGQGRGRWKCD 556
Score = 79.7 bits (195), Expect = 3e-14
Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)
Query: 473 NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
+ GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C + C D TY+V + +
Sbjct: 2043 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2099
Query: 533 KRHEEGHMLNCTCFGQGRGRWKCD 556
K + G + +CTCFG RG W+CD
Sbjct: 2100 KEY-LGAICSCTCFGGQRG-WRCD 2121
Score = 63.5 bits (153), Expect = 2e-09
Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)
Query: 2220 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2274
C+DNG +Y+I ++W+R G + CTC G +G F C+ E TC+D G TY VG
Sbjct: 52 CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
Query: 2275 EQWQKEYLGAICSCTCFGGQRG 2296
+ +++ I CTC G RG
Sbjct: 110 DTYERPKDSMIWDCTCIGAGRG 131
Score = 63.5 bits (153), Expect = 2e-09
Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)
Query: 52 CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
C+DNG +Y+I ++W+R G + CTC G +G F C+ E TC+D G TY VG
Sbjct: 2041 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2095
Query: 110 DTYERPKDSMIWDCTCIGAGRG 131
+ +++ I CTC G RG
Sbjct: 2096 EQWQKEYLGAICSCTCFGGQRG 2117
Score = 62.0 bits (149), Expect = 7e-09
Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)
Query: 2159 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2214
VGN E +Q D D T Y V D + + E G L C C G G G ++C
Sbjct: 499 VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
Query: 2215 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2259
D C D+ G Y+IG+ W++ +G C C G G GE+ C P
Sbjct: 556 DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
Score = 62.0 bits (149), Expect = 7e-09
Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)
Query: 499 VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
VGN E +Q D D T Y V D + + E G L C C G G G ++C
Sbjct: 1980 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2035
Query: 556 DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
D C D+ G Y+IG+ W++ +G C C G G GE+ C P
Sbjct: 2036 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2080
Score = 57.8 bits (138), Expect = 1e-07
Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 2264 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2323
CYD+GK Y + +QW++ YLG CTC+GG RG+ C++ +P E T Y +
Sbjct: 52 CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
Query: 2324 QR 2325
R
Sbjct: 106 YR 107
Score = 57.8 bits (138), Expect = 1e-07
Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 52 CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
CYD+GK Y + +QW++ YLG CTC+GG RG+ C++ +P E T Y +
Sbjct: 2085 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2144
Query: 106 YR 107
R
Sbjct: 2145 QR 2146
Score = 50.1 bits (118), Expect = 3e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)
Query: 2175 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2216
C D T + Y +GD W + G L C C G G G ++C+
Sbjct: 231 CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
Query: 2217 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2251
D+GV Y +G +W + N QM+ CTCLGNG
Sbjct: 291 AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
Score = 50.1 bits (118), Expect = 3e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)
Query: 231 CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
C D T + Y +GD W + G L C C G G G ++C+
Sbjct: 1996 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2037
Query: 291 AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
D+GV Y +G +W + N QM+ CTCLGNG
Sbjct: 2038 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2072
>gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens]
Length = 2296
Score = 3522 bits (9132), Expect = 0.0
Identities = 1710/1901 (89%), Positives = 1757/1901 (92%), Gaps = 10/1901 (0%)
Query: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
Query: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
Query: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
Query: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
Query: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
Query: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
Query: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
Query: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
Query: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
Query: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
Query: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
Query: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
Query: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
Query: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
Query: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
Query: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
Query: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
Query: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD
Sbjct: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
Query: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA
Sbjct: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
Query: 1381 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440
PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL
Sbjct: 1381 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440
Query: 1441 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500
IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK
Sbjct: 1441 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500
Query: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1560
STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV
Sbjct: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1560
Query: 1561 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE
Sbjct: 1561 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
Query: 1621 SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPE--DGIHELFP 1678
SQPLVQTAVT I P L FT V S+ W P Q++ YRV + E + E+
Sbjct: 1621 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1680
Query: 1679 APDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA--IPAPTDLKFTQVTPT 1736
APD + + GL ++Y VSV AL D + S+P G +T + P + T T T
Sbjct: 1681 APD--SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATET 1738
Query: 1737 SLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1796
+++ W +TG++V P P++ + PD S ++GL T Y++ +Y L
Sbjct: 1739 TITISWRTKTETITGFQVDAVPANGQTPIQR-TIKPDVRSYTITGLQPGTDYKIYLYTLN 1797
Query: 1797 DTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVD-AVPANGQT 1855
D S P V+ + P R T ++ +SW+ ITG+ + P +
Sbjct: 1798 DNARSSPV--VIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPR 1855
Query: 1856 PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV 1896
+ +P V TITGL+PGT+Y IY+ L +N +S P++
Sbjct: 1856 EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLI 1896
Score = 1696 bits (4393), Expect = 0.0
Identities = 921/1665 (55%), Positives = 1103/1665 (66%), Gaps = 104/1665 (6%)
Query: 768 LPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAP------------- 814
+P S I L PG Y + I + G Q + TT+ P
Sbjct: 659 IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
Query: 815 -----PDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTE-LNLPETANSVTLS 868
+V ++ +S VV W ++G+R+ Y S EG + L+LP TA SV +
Sbjct: 719 SPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778
Query: 869 DLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWT 928
DL PG +Y + +Y + E+ E + ++ +TT +P D +V D + + W+
Sbjct: 779 DLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPD------APPDPTVDQVDDTSIVVRWS 832
Query: 929 PPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP 988
P++ +TGYR+ P LP + N+ ++ L PGV Y ++AV +ES P
Sbjct: 833 RPQAPITGYRIVYSPSVEGSSTELNLPETANSVT-LSDLQPGVQYNITIYAVEENQESTP 891
Query: 989 LTAQQTTK-------LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQ 1041
+ QQ T + +P +LQFV TD V + WTPP + +TGYR+ V P +
Sbjct: 892 VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDV--IPVNLPGE 949
Query: 1042 YNVGPSVSKYP---LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEV 1098
+ +S+ + L P Y + A+ +ES T TT + + E
Sbjct: 950 HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE- 1008
Query: 1099 TETTIVITWTP--APRIGFKLGVRPSQGGEAPRE--VTSDSGSIVVSGLTPGVEYVYTIQ 1154
T++T+++ WTP A G++L V ++ G+ PR+ V + L P EY ++
Sbjct: 1009 TDSTVLVRWTPPRAQITGYRLTVGLTRRGQ-PRQYNVGPSVSKYPLRNLQPASEYTVSLV 1067
Query: 1155 VLRDGQERDAPIVNKVVTPLSPPTNL---HLEANPDTGVLTVSWERSTTPDITGYRITTT 1211
++ QE +P V T L P +++ + E T V+T W T G+++
Sbjct: 1068 AIKGNQE--SPKATGVFTTLQPGSSIPPYNTEVTETTIVIT--W---TPAPRIGFKLGVR 1120
Query: 1212 PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE-SVPISDTIIPAVPPP 1270
P+ QG V +D S L+PG+EY ++ ++D +E PI + ++ + PP
Sbjct: 1121 PS---QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPP 1177
Query: 1271 TDLRFTNIGPDT--MRVTWAPPPSIDLTNFLVRYSPVKNEE-DVAELSISPSDNAVVLTN 1327
T+L PDT + V+W + D+T + + +P ++ + E + ++ N
Sbjct: 1178 TNLHL-EANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDN 1236
Query: 1328 LLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRAT-IT 1386
L PG EY VSV +V + ES P+ + PT + F++I ++ V W P + +T
Sbjct: 1237 LSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLT 1296
Query: 1387 GYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQST 1446
+ +R+ P E + S N++ LTNL PGTEYVVS+ ++ + ES L G+Q T
Sbjct: 1297 NFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT 1356
Query: 1447 VSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATIS 1506
D P ++ T S + W AP T+ YRI + + +E VP S+++ T++
Sbjct: 1357 GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT 1416
Query: 1507 GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSS 1566
L PG +Y +++ A+ GR +SP S T D P ++V S+ + W +
Sbjct: 1417 NLTPGTEYVVSIVALNGREESPLLIGQQS----TVSDVPRDLEVVAATPTSLLISWDAPA 1472
Query: 1567 SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES----Q 1622
V YR+T G P + T ++ TI GL+P V+Y ++VYA G+S +
Sbjct: 1473 VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSK 1532
Query: 1623 PLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDG 1682
P+ T ID+P + TDV +SI + W V+ YRVT ++P++G G
Sbjct: 1533 PISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVT-TTPKNGPGPTKTKTAG 1591
Query: 1683 EEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQ 1741
+ T ++GL+P EY VSV A + ESQPL+ T T IPAPTDLKFTQVTPTSLSAQ
Sbjct: 1592 PDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQ 1651
Query: 1742 WTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1801
WTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS
Sbjct: 1652 WTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1711
Query: 1802 RPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTI 1861
RPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTI
Sbjct: 1712 RPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTI 1771
Query: 1862 KPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLV 1921
KPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLV
Sbjct: 1772 KPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLV 1831
Query: 1922 SWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 1981
SWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK
Sbjct: 1832 SWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 1891
Query: 1982 SEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSG 2041
SEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSG
Sbjct: 1892 SEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSG 1951
Query: 2042 QQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVG-------------------- 2081
QQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVG
Sbjct: 1952 QQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPH 2011
Query: 2082 -----------QEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTG 2130
QEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTG
Sbjct: 2012 GPGLNPNASTGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTG 2071
Query: 2131 LTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEW 2190
LTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEW
Sbjct: 2072 LTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEW 2131
Query: 2191 ERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGN 2250
ERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGN
Sbjct: 2132 ERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGN 2191
Query: 2251 GKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPS 2310
GKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPS
Sbjct: 2192 GKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPS 2251
Query: 2311 PEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE 2355
PEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE
Sbjct: 2252 PEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE 2296
Score = 115 bits (287), Expect = 7e-25
Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)
Query: 2172 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2231
+++CFD YT + Y VGD +ER +S C C+G G G C + CH+ G +YKIG+
Sbjct: 94 EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
Query: 2232 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2287
W R E G M+ C CLGNGKGE+ C P C+D G +Y VGE W+K Y G +
Sbjct: 153 TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
Query: 2288 CTCFGGQRG 2296
CTC G G
Sbjct: 213 CTCLGEGSG 221
Score = 115 bits (287), Expect = 7e-25
Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)
Query: 94 EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
+++CFD YT + Y VGD +ER +S C C+G G G C + CH+ G +YKIG+
Sbjct: 2113 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2172
Query: 153 TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
W R E G M+ C CLGNGKGE+ C P C+D G +Y VGE W+K Y G +
Sbjct: 2173 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2228
Query: 213 CTCLGEGSG 221
CTC G G
Sbjct: 2229 CTCFGGQRG 2237
Score = 98.6 bits (244), Expect = 6e-20
Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)
Query: 2155 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2214
E V +GN E +P + CFD + Y VG+ WE+ + + C CLG GSG C
Sbjct: 166 ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
Query: 2215 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2260
S C+D +Y+IG+ W ++ G ++ C C GNG+GE+KC+ H
Sbjct: 226 TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
Query: 2261 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2292
A Y D G Y VG QW K CTC G
Sbjct: 286 FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
Score = 98.6 bits (244), Expect = 6e-20
Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)
Query: 166 ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
E V +GN E +P + CFD + Y VG+ WE+ + + C CLG GSG C
Sbjct: 2096 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2155
Query: 226 TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
S C+D +Y+IG+ W ++ G ++ C C GNG+GE+KC+ H
Sbjct: 2156 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2201
Query: 286 FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
A Y D G Y VG QW K CTC G
Sbjct: 2202 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2233
Score = 90.9 bits (224), Expect = 1e-17
Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)
Query: 2184 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2239
Y +GD+W++ + G + C C+G G G + C + D + + Y + + + ++ E
Sbjct: 478 YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
Query: 2240 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2296
G M++CTC G G+G +KCDP + C D G Y +G+ W+K G C C+G G
Sbjct: 538 GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
Query: 2297 WRC 2299
W C
Sbjct: 597 WHC 599
Score = 90.9 bits (224), Expect = 1e-17
Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)
Query: 478 YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
Y +GD+W++ + G + C C+G G G + C + D + + Y + + + ++ E
Sbjct: 2125 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2180
Query: 538 GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
G M++CTC G G+G +KCDP + C D G Y +G+ W+K G C C+G G
Sbjct: 2181 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2237
Query: 597 WHC 599
W C
Sbjct: 2238 WRC 2240
Score = 88.2 bits (217), Expect = 9e-17
Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)
Query: 2184 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2239
Y +GD W R E+G + L C CLG G G + C + C D+ G +Y +GE W++ +
Sbjct: 148 YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
Query: 2240 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2296
M+ CTCLG G G C D +T Y +G+ W +K+ G + C C G RG
Sbjct: 208 WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
Query: 2297 WRCD 2300
W+C+
Sbjct: 268 WKCE 271
Score = 88.2 bits (217), Expect = 9e-17
Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)
Query: 148 YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
Y +GD W R E+G + L C CLG G G + C + C D+ G +Y +GE W++ +
Sbjct: 2125 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2180
Query: 208 WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
M+ CTCLG G G C D +T Y +G+ W +K+ G + C C G RG
Sbjct: 2181 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2237
Query: 268 WKCE 271
W+C+
Sbjct: 2238 WRCD 2241
Score = 79.7 bits (195), Expect = 3e-14
Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)
Query: 2222 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2278
+ GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C + C D TY+V + +
Sbjct: 473 NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
Query: 2279 KEY-LGAICSCTCFGGQRG-WRCD 2300
K + G + +CTCFG RG W+CD
Sbjct: 533 KRHEEGHMLNCTCFGQGRGRWKCD 556
Score = 79.7 bits (195), Expect = 3e-14
Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)
Query: 473 NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
+ GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C + C D TY+V + +
Sbjct: 2163 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2219
Query: 533 KRHEEGHMLNCTCFGQGRGRWKCD 556
K + G + +CTCFG RG W+CD
Sbjct: 2220 KEY-LGAICSCTCFGGQRG-WRCD 2241
Score = 63.5 bits (153), Expect = 2e-09
Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)
Query: 2220 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2274
C+DNG +Y+I ++W+R G + CTC G +G F C+ E TC+D G TY VG
Sbjct: 52 CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
Query: 2275 EQWQKEYLGAICSCTCFGGQRG 2296
+ +++ I CTC G RG
Sbjct: 110 DTYERPKDSMIWDCTCIGAGRG 131
Score = 63.5 bits (153), Expect = 2e-09
Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)
Query: 52 CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
C+DNG +Y+I ++W+R G + CTC G +G F C+ E TC+D G TY VG
Sbjct: 2161 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2215
Query: 110 DTYERPKDSMIWDCTCIGAGRG 131
+ +++ I CTC G RG
Sbjct: 2216 EQWQKEYLGAICSCTCFGGQRG 2237
Score = 62.0 bits (149), Expect = 7e-09
Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)
Query: 2159 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2214
VGN E +Q D D T Y V D + + E G L C C G G G ++C
Sbjct: 499 VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
Query: 2215 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2259
D C D+ G Y+IG+ W++ +G C C G G GE+ C P
Sbjct: 556 DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
Score = 62.0 bits (149), Expect = 7e-09
Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)
Query: 499 VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
VGN E +Q D D T Y V D + + E G L C C G G G ++C
Sbjct: 2100 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2155
Query: 556 DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
D C D+ G Y+IG+ W++ +G C C G G GE+ C P
Sbjct: 2156 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2200
Score = 57.8 bits (138), Expect = 1e-07
Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 2264 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2323
CYD+GK Y + +QW++ YLG CTC+GG RG+ C++ +P E T Y +
Sbjct: 52 CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
Query: 2324 QR 2325
R
Sbjct: 106 YR 107
Score = 57.8 bits (138), Expect = 1e-07
Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 52 CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
CYD+GK Y + +QW++ YLG CTC+GG RG+ C++ +P E T Y +
Sbjct: 2205 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2264
Query: 106 YR 107
R
Sbjct: 2265 QR 2266
Score = 55.5 bits (132), Expect = 6e-07
Identities = 82/340 (24%), Positives = 131/340 (38%), Gaps = 54/340 (15%)
Query: 1858 QRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID---ASTAIDAPSNLRFLAT 1914
+ TI + SYTI GL+PG Y+ L ++ D ST+ SN T
Sbjct: 656 EATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGET 715
Query: 1915 TP----------------NSLLVSWQPPRARITGYIIKYE--KPGSPPREV-VPRPRPGV 1955
TP +S +VSW ++G+ ++YE + G P+ + +P
Sbjct: 716 TPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPST---A 772
Query: 1956 TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT--------------DELPQLV--T 1999
T I L PG +Y + V + + + ++ +T D+ +V +
Sbjct: 773 TSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS 832
Query: 2000 LPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQM-IFEEHGFR 2058
P + G I+ PS + + P +T N + L S QP V + I+ +
Sbjct: 833 RPQAPITGYRIVYSPSVEGSSTELNLP--ETANSVTL---SDLQPGVQYNITIYAVEENQ 887
Query: 2059 RTTP-----PTTATPIRHR-PRPYPPNVGQEALSQTTISWAPFQD-TSEYIISCHPVGTD 2111
+TP TT TP P P + + TI W P + + Y + PV
Sbjct: 888 ESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLP 947
Query: 2112 EEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHK 2151
E Q +T A +TGL+ G TY V A+ + K
Sbjct: 948 GEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESK 987
Score = 50.1 bits (118), Expect = 3e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)
Query: 2175 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2216
C D T + Y +GD W + G L C C G G G ++C+
Sbjct: 231 CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
Query: 2217 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2251
D+GV Y +G +W + N QM+ CTCLGNG
Sbjct: 291 AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
Score = 50.1 bits (118), Expect = 3e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)
Query: 231 CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
C D T + Y +GD W + G L C C G G G ++C+
Sbjct: 2116 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2157
Query: 291 AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
D+GV Y +G +W + N QM+ CTCLGNG
Sbjct: 2158 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2192
>gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens]
Length = 2477
Score = 3002 bits (7783), Expect = 0.0
Identities = 1486/1997 (74%), Positives = 1617/1997 (80%), Gaps = 21/1997 (1%)
Query: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
Query: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
Query: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
Query: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
Query: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
Query: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
Query: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
Query: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
Query: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
Query: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
Query: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
Query: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
Query: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
Query: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
Query: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
Query: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
Query: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
Query: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
DTIIP VP TDL F +I ++ + W P S + + + + E + S
Sbjct: 1261 DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSV 1320
Query: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
+T L PG +Y +SV ++ ES P Q+T + PT + F++I ++ V W
Sbjct: 1321 GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP 1380
Query: 1381 PRA-TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPL 1439
P + +T + +R+ P E + S N++ LTNL PGTEYVVS+ ++ + ES
Sbjct: 1381 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP 1440
Query: 1440 LIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGS 1499
L G+Q T D P ++ T S + W AP T+ YRI + + +E VP S
Sbjct: 1441 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS 1500
Query: 1500 KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS 1559
+++ T++ L PG +Y +++ A+ GR +SP + T D P ++V S+
Sbjct: 1501 RNSITLTNLTPGTEYVVSIVALNGREESPL----LIGQQSTVSDVPRDLEVVAATPTSLL 1556
Query: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619
+ W + V YR+T G P + T ++ TI GL+P V+Y ++VYA G
Sbjct: 1557 ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1616
Query: 1620 E----SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHE 1675
+ S+P+ T ID+P + TDV +SI + W V+ YRVT ++P++G
Sbjct: 1617 DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVT-TTPKNGPGP 1675
Query: 1676 LFPAPDGEEDT-AELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVT 1734
G + T ++GL+P EY VSV A + ESQPL+ T T I P L FT V
Sbjct: 1676 TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVD 1735
Query: 1735 PTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKYEVSV 1792
S+ W P Q++ YRV + E + E+ APD + + GL ++Y VSV
Sbjct: 1736 VDSIKIAWESPQGQVSRYRVTYSSPE--DGIHELFPAPDGEEDTAELQGLRPGSEYTVSV 1793
Query: 1793 YALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPAN 1852
AL D + S+P G +T + P + T T T+++ W +TG++V P
Sbjct: 1794 VALHDDMESQPLIGTQSTA--IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKE 1851
Query: 1853 GQTPIQR-TIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV--VIDASTAIDAPSNL 1909
P++ + PD S ++GL T Y++ +Y L D S P V+ + P
Sbjct: 1852 KTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRA 1911
Query: 1910 RFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEY 1969
R T ++ +SW+ ITG+ + P + + +P V TITGL+PGT+Y
Sbjct: 1912 RVTDATETTITISWRTKTETITGFQVD-AVPANGQTPIQRTIKPDVRSYTITGLQPGTDY 1970
Query: 1970 TIYVIALKNNQKSEPLI 1986
IY+ L +N +S P++
Sbjct: 1971 KIYLYTLNDNARSSPVV 1987
Score = 2422 bits (6278), Expect = 0.0
Identities = 1260/1752 (71%), Positives = 1369/1752 (78%), Gaps = 97/1752 (5%)
Query: 659 IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
+P S I L PG Y + I + G Q + TT+ P
Sbjct: 768 LPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAP------------- 814
Query: 719 SPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778
+V ++ +S VV W ++G+R+ Y S EG + L+LP TA SV +
Sbjct: 815 -----PDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTE-LNLPETANSVTLS 868
Query: 779 DLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPD------APPDPTVDQVDDTSIVVRWS 832
DL PG +Y + +Y + E+ E + ++ +TT +P D +V D + + W+
Sbjct: 869 DLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWT 928
Query: 833 RPQAPITGYRIVYSPSVEGSSTELNLPETANSVT-LSDLQPGVQYNITIYAVEENQESTP 891
P++ +TGYR+ P LP + N+ ++ L PGV Y ++AV +ES P
Sbjct: 929 PPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP 988
Query: 892 VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHG 951
+ QQ T + +P +LQFV TD V + WTPP + +TGYR+ V G
Sbjct: 989 LTAQQTTK-------LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV------GLTR 1035
Query: 952 QRLPISRNTFAEVT-----GLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFV 1006
+ P N V+ L P Y + A+ +ES T TT + +
Sbjct: 1036 RGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN 1095
Query: 1007 NE-TDSTVLVRWTPPRAQITGYRLTVGLTRRGQ-PRQYNVGPSVSKYPLRNLQPASEYTV 1064
E T++T+++ WTP A G++L V ++ G+ PR+ V + L P EY
Sbjct: 1096 TEVTETTIVITWTP--APRIGFKLGVRPSQGGEAPRE--VTSDSGSIVVSGLTPGVEYVY 1151
Query: 1065 SLVAIKGNQE--SPKATGVFTTLQPGSSIPPYNTEVTETTIVIT--W---TPAPRIGFKL 1117
++ ++ QE +P V T L P +++ + E T V+T W T G+++
Sbjct: 1152 TIQVLRDGQERDAPIVNKVVTPLSPPTNL---HLEANPDTGVLTVSWERSTTPDITGYRI 1208
Query: 1118 GVRPS---QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPL 1174
P+ QG V +D S L+PG+EY ++ ++D +E PI + ++ +
Sbjct: 1209 TTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE-SVPISDTIIPEV 1267
Query: 1175 SPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTF 1234
T+L D+ + + W + I GYRIT G+ E+ V + T
Sbjct: 1268 PQLTDLSFVDITDSSI-GLRWTPLNSSTIIGYRITVVAA-GEGIPIFEDFVDSSVGYYTV 1325
Query: 1235 DNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSID 1294
L PG++Y++SV T+ + ES P + T AVPPPTDLRFTNIGPDTMRVTWAPPPSID
Sbjct: 1326 TGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSID 1385
Query: 1295 LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ 1354
LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ
Sbjct: 1386 LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ 1445
Query: 1355 KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT 1414
KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT
Sbjct: 1446 KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT 1505
Query: 1415 LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT 1474
LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT
Sbjct: 1506 LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT 1565
Query: 1475 VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPI 1534
VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPI
Sbjct: 1566 VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPI 1625
Query: 1535 SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594
SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ
Sbjct: 1626 SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1685
Query: 1595 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWES 1654
TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWES
Sbjct: 1686 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWES 1745
Query: 1655 PQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPL 1714
PQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPL
Sbjct: 1746 PQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPL 1805
Query: 1715 IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS 1774
IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS
Sbjct: 1806 IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS 1865
Query: 1775 SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISW 1834
SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISW
Sbjct: 1866 SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISW 1925
Query: 1835 RTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP 1894
RTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP
Sbjct: 1926 RTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP 1985
Query: 1895 VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPG 1954
VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPG
Sbjct: 1986 VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPG 2045
Query: 1955 VTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVP 2014
VTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVP
Sbjct: 2046 VTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVP 2105
Query: 2015 STVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPR 2074
STVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPR
Sbjct: 2106 STVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPR 2165
Query: 2075 PYPPNVG-------------------------------QEALSQTTISWAPFQDTSEYII 2103
PYPPNVG QEALSQTTISWAPFQDTSEYII
Sbjct: 2166 PYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDTSEYII 2225
Query: 2104 SCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSV 2163
SCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSV
Sbjct: 2226 SCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSV 2285
Query: 2164 NEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDN 2223
NEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDN
Sbjct: 2286 NEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDN 2345
Query: 2224 GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLG 2283
GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLG
Sbjct: 2346 GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLG 2405
Query: 2284 AICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMP 2343
AICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMP
Sbjct: 2406 AICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMP 2465
Query: 2344 LDVQADREDSRE 2355
LDVQADREDSRE
Sbjct: 2466 LDVQADREDSRE 2477
Score = 115 bits (287), Expect = 7e-25
Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)
Query: 2172 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2231
+++CFD YT + Y VGD +ER +S C C+G G G C + CH+ G +YKIG+
Sbjct: 94 EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
Query: 2232 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2287
W R E G M+ C CLGNGKGE+ C P C+D G +Y VGE W+K Y G +
Sbjct: 153 TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
Query: 2288 CTCFGGQRG 2296
CTC G G
Sbjct: 213 CTCLGEGSG 221
Score = 115 bits (287), Expect = 7e-25
Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)
Query: 94 EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
+++CFD YT + Y VGD +ER +S C C+G G G C + CH+ G +YKIG+
Sbjct: 2294 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2353
Query: 153 TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
W R E G M+ C CLGNGKGE+ C P C+D G +Y VGE W+K Y G +
Sbjct: 2354 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2409
Query: 213 CTCLGEGSG 221
CTC G G
Sbjct: 2410 CTCFGGQRG 2418
Score = 98.6 bits (244), Expect = 6e-20
Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)
Query: 2155 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2214
E V +GN E +P + CFD + Y VG+ WE+ + + C CLG GSG C
Sbjct: 166 ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
Query: 2215 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2260
S C+D +Y+IG+ W ++ G ++ C C GNG+GE+KC+ H
Sbjct: 226 TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
Query: 2261 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2292
A Y D G Y VG QW K CTC G
Sbjct: 286 FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
Score = 98.6 bits (244), Expect = 6e-20
Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)
Query: 166 ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
E V +GN E +P + CFD + Y VG+ WE+ + + C CLG GSG C
Sbjct: 2277 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2336
Query: 226 TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
S C+D +Y+IG+ W ++ G ++ C C GNG+GE+KC+ H
Sbjct: 2337 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2382
Query: 286 FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
A Y D G Y VG QW K CTC G
Sbjct: 2383 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2414
Score = 90.9 bits (224), Expect = 1e-17
Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)
Query: 2184 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2239
Y +GD+W++ + G + C C+G G G + C + D + + Y + + + ++ E
Sbjct: 478 YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
Query: 2240 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2296
G M++CTC G G+G +KCDP + C D G Y +G+ W+K G C C+G G
Sbjct: 538 GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
Query: 2297 WRC 2299
W C
Sbjct: 597 WHC 599
Score = 90.9 bits (224), Expect = 1e-17
Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)
Query: 478 YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
Y +GD+W++ + G + C C+G G G + C + D + + Y + + + ++ E
Sbjct: 2306 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2361
Query: 538 GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
G M++CTC G G+G +KCDP + C D G Y +G+ W+K G C C+G G
Sbjct: 2362 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2418
Query: 597 WHC 599
W C
Sbjct: 2419 WRC 2421
Score = 88.2 bits (217), Expect = 9e-17
Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)
Query: 2184 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2239
Y +GD W R E+G + L C CLG G G + C + C D+ G +Y +GE W++ +
Sbjct: 148 YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
Query: 2240 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2296
M+ CTCLG G G C D +T Y +G+ W +K+ G + C C G RG
Sbjct: 208 WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
Query: 2297 WRCD 2300
W+C+
Sbjct: 268 WKCE 271
Score = 88.2 bits (217), Expect = 9e-17
Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)
Query: 148 YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
Y +GD W R E+G + L C CLG G G + C + C D+ G +Y +GE W++ +
Sbjct: 2306 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2361
Query: 208 WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
M+ CTCLG G G C D +T Y +G+ W +K+ G + C C G RG
Sbjct: 2362 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2418
Query: 268 WKCE 271
W+C+
Sbjct: 2419 WRCD 2422
Score = 79.7 bits (195), Expect = 3e-14
Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)
Query: 2222 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2278
+ GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C + C D TY+V + +
Sbjct: 473 NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
Query: 2279 KEY-LGAICSCTCFGGQRG-WRCD 2300
K + G + +CTCFG RG W+CD
Sbjct: 533 KRHEEGHMLNCTCFGQGRGRWKCD 556
Score = 79.7 bits (195), Expect = 3e-14
Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)
Query: 473 NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
+ GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C + C D TY+V + +
Sbjct: 2344 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2400
Query: 533 KRHEEGHMLNCTCFGQGRGRWKCD 556
K + G + +CTCFG RG W+CD
Sbjct: 2401 KEY-LGAICSCTCFGGQRG-WRCD 2422
Score = 63.5 bits (153), Expect = 2e-09
Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)
Query: 2220 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2274
C+DNG +Y+I ++W+R G + CTC G +G F C+ E TC+D G TY VG
Sbjct: 52 CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
Query: 2275 EQWQKEYLGAICSCTCFGGQRG 2296
+ +++ I CTC G RG
Sbjct: 110 DTYERPKDSMIWDCTCIGAGRG 131
Score = 63.5 bits (153), Expect = 2e-09
Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)
Query: 52 CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
C+DNG +Y+I ++W+R G + CTC G +G F C+ E TC+D G TY VG
Sbjct: 2342 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2396
Query: 110 DTYERPKDSMIWDCTCIGAGRG 131
+ +++ I CTC G RG
Sbjct: 2397 EQWQKEYLGAICSCTCFGGQRG 2418
Score = 62.0 bits (149), Expect = 7e-09
Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)
Query: 2159 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2214
VGN E +Q D D T Y V D + + E G L C C G G G ++C
Sbjct: 499 VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
Query: 2215 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2259
D C D+ G Y+IG+ W++ +G C C G G GE+ C P
Sbjct: 556 DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
Score = 62.0 bits (149), Expect = 7e-09
Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)
Query: 499 VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
VGN E +Q D D T Y V D + + E G L C C G G G ++C
Sbjct: 2281 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2336
Query: 556 DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
D C D+ G Y+IG+ W++ +G C C G G GE+ C P
Sbjct: 2337 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2381
Score = 57.8 bits (138), Expect = 1e-07
Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 2264 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2323
CYD+GK Y + +QW++ YLG CTC+GG RG+ C++ +P E T Y +
Sbjct: 52 CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
Query: 2324 QR 2325
R
Sbjct: 106 YR 107
Score = 57.8 bits (138), Expect = 1e-07
Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 52 CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
CYD+GK Y + +QW++ YLG CTC+GG RG+ C++ +P E T Y +
Sbjct: 2386 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2445
Query: 106 YR 107
R
Sbjct: 2446 QR 2447
Score = 50.1 bits (118), Expect = 3e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)
Query: 2175 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2216
C D T + Y +GD W + G L C C G G G ++C+
Sbjct: 231 CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
Query: 2217 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2251
D+GV Y +G +W + N QM+ CTCLGNG
Sbjct: 291 AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
Score = 50.1 bits (118), Expect = 3e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)
Query: 231 CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
C D T + Y +GD W + G L C C G G G ++C+
Sbjct: 2297 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2338
Query: 291 AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
D+GV Y +G +W + N QM+ CTCLGNG
Sbjct: 2339 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2373
Score = 45.8 bits (107), Expect = 5e-04
Identities = 83/370 (22%), Positives = 138/370 (37%), Gaps = 83/370 (22%)
Query: 656 EATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGET 715
+ TI + SYTI GL+PG Y+ L ++ D ST+ SN T
Sbjct: 1949 QRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID---ASTAIDAPSNLRFLAT 2005
Query: 716 TPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPST---A 772
TP +S +VSW ++G+ ++YE + G P+ + +P
Sbjct: 2006 TP----------------NSLLVSWQPPRARITGYIIKYE--KPGSPPREV-VPRPRPGV 2046
Query: 773 TSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS 832
T I L PG +Y + V + + + ++ +T D+ +V +
Sbjct: 2047 TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT--------------DELPQLV--T 2090
Query: 833 RPQAPITGYRIVYSPSVEGSSTELNLP--ETANSVTL---SDLQPGVQYNITIYAVEENQ 887
P + G I+ PS + + P +T N + L S QP V + I+ +
Sbjct: 2091 LPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQM-IFEEHGFR 2149
Query: 888 ESTPVVIQQETTGTP-RSDTVPSPRDL-QFVEVTDV------------------------ 921
+TP TT TP R P P ++ + +++ +
Sbjct: 2150 RTTP-----PTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQ 2204
Query: 922 ----KVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
+ TI W P + + Y + PV E Q +T A +TGL+ G TY V
Sbjct: 2205 EALSQTTISWAPFQD-TSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIV 2263
Query: 978 FAVSHGRESK 987
A+ + K
Sbjct: 2264 EALKDQQRHK 2273
Score = 32.7 bits (73), Expect = 4.3
Identities = 29/126 (23%), Positives = 53/126 (42%), Gaps = 20/126 (15%)
Query: 2041 GQQPSV---GQQMIFEEHGFRR----------TTPPTTATPIRHRPRPYPPNVG-QEALS 2086
G +P V GQ + +++G + T+ P T+ + P+ P V E+++
Sbjct: 670 GLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVT 729
Query: 2087 QTT-----ISWAPFQDT-SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNII 2140
+ T +SW DT S + + +EP +P T+TS + L G Y +
Sbjct: 730 EITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVN 789
Query: 2141 VEALKD 2146
V + +
Sbjct: 790 VYQISE 795
>gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens]
Length = 2421
Score = 3002 bits (7783), Expect = 0.0
Identities = 1486/1997 (74%), Positives = 1617/1997 (80%), Gaps = 21/1997 (1%)
Query: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
Query: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
Query: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
Query: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
Query: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
Query: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
Query: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
Query: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
Query: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
Query: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
Query: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
Query: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
Query: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
Query: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
Query: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
Query: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
Query: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
Query: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
DTIIP VP TDL F +I ++ + W P S + + + + E + S
Sbjct: 1261 DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSV 1320
Query: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
+T L PG +Y +SV ++ ES P Q+T + PT + F++I ++ V W
Sbjct: 1321 GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP 1380
Query: 1381 PRA-TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPL 1439
P + +T + +R+ P E + S N++ LTNL PGTEYVVS+ ++ + ES
Sbjct: 1381 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP 1440
Query: 1440 LIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGS 1499
L G+Q T D P ++ T S + W AP T+ YRI + + +E VP S
Sbjct: 1441 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS 1500
Query: 1500 KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS 1559
+++ T++ L PG +Y +++ A+ GR +SP + T D P ++V S+
Sbjct: 1501 RNSITLTNLTPGTEYVVSIVALNGREESPL----LIGQQSTVSDVPRDLEVVAATPTSLL 1556
Query: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619
+ W + V YR+T G P + T ++ TI GL+P V+Y ++VYA G
Sbjct: 1557 ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1616
Query: 1620 E----SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHE 1675
+ S+P+ T ID+P + TDV +SI + W V+ YRVT ++P++G
Sbjct: 1617 DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVT-TTPKNGPGP 1675
Query: 1676 LFPAPDGEEDT-AELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVT 1734
G + T ++GL+P EY VSV A + ESQPL+ T T I P L FT V
Sbjct: 1676 TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVD 1735
Query: 1735 PTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKYEVSV 1792
S+ W P Q++ YRV + E + E+ APD + + GL ++Y VSV
Sbjct: 1736 VDSIKIAWESPQGQVSRYRVTYSSPE--DGIHELFPAPDGEEDTAELQGLRPGSEYTVSV 1793
Query: 1793 YALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPAN 1852
AL D + S+P G +T + P + T T T+++ W +TG++V P
Sbjct: 1794 VALHDDMESQPLIGTQSTA--IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKE 1851
Query: 1853 GQTPIQR-TIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV--VIDASTAIDAPSNL 1909
P++ + PD S ++GL T Y++ +Y L D S P V+ + P
Sbjct: 1852 KTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRA 1911
Query: 1910 RFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEY 1969
R T ++ +SW+ ITG+ + P + + +P V TITGL+PGT+Y
Sbjct: 1912 RVTDATETTITISWRTKTETITGFQVD-AVPANGQTPIQRTIKPDVRSYTITGLQPGTDY 1970
Query: 1970 TIYVIALKNNQKSEPLI 1986
IY+ L +N +S P++
Sbjct: 1971 KIYLYTLNDNARSSPVV 1987
Score = 2372 bits (6148), Expect = 0.0
Identities = 1235/1721 (71%), Positives = 1344/1721 (78%), Gaps = 91/1721 (5%)
Query: 659 IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
+P S I L PG Y + I + G Q + TT+ P
Sbjct: 768 LPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAP------------- 814
Query: 719 SPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778
+V ++ +S VV W ++G+R+ Y S EG + L+LP TA SV +
Sbjct: 815 -----PDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTE-LNLPETANSVTLS 868
Query: 779 DLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPD------APPDPTVDQVDDTSIVVRWS 832
DL PG +Y + +Y + E+ E + ++ +TT +P D +V D + + W+
Sbjct: 869 DLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWT 928
Query: 833 RPQAPITGYRIVYSPSVEGSSTELNLPETANSVT-LSDLQPGVQYNITIYAVEENQESTP 891
P++ +TGYR+ P LP + N+ ++ L PGV Y ++AV +ES P
Sbjct: 929 PPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP 988
Query: 892 VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHG 951
+ QQ T + +P +LQFV TD V + WTPP + +TGYR+ V G
Sbjct: 989 LTAQQTTK-------LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV------GLTR 1035
Query: 952 QRLPISRNTFAEVT-----GLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFV 1006
+ P N V+ L P Y + A+ +ES T TT + +
Sbjct: 1036 RGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN 1095
Query: 1007 NE-TDSTVLVRWTPPRAQITGYRLTVGLTRRGQ-PRQYNVGPSVSKYPLRNLQPASEYTV 1064
E T++T+++ WTP A G++L V ++ G+ PR+ V + L P EY
Sbjct: 1096 TEVTETTIVITWTP--APRIGFKLGVRPSQGGEAPRE--VTSDSGSIVVSGLTPGVEYVY 1151
Query: 1065 SLVAIKGNQE--SPKATGVFTTLQPGSSIPPYNTEVTETTIVIT--W---TPAPRIGFKL 1117
++ ++ QE +P V T L P +++ + E T V+T W T G+++
Sbjct: 1152 TIQVLRDGQERDAPIVNKVVTPLSPPTNL---HLEANPDTGVLTVSWERSTTPDITGYRI 1208
Query: 1118 GVRPS---QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPL 1174
P+ QG V +D S L+PG+EY ++ ++D +E PI + ++ +
Sbjct: 1209 TTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE-SVPISDTIIPEV 1267
Query: 1175 SPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTF 1234
T+L D+ + + W + I GYRIT G+ E+ V + T
Sbjct: 1268 PQLTDLSFVDITDSSI-GLRWTPLNSSTIIGYRITVVAA-GEGIPIFEDFVDSSVGYYTV 1325
Query: 1235 DNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSID 1294
L PG++Y++SV T+ + ES P + T AVPPPTDLRFTNIGPDTMRVTWAPPPSID
Sbjct: 1326 TGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSID 1385
Query: 1295 LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ 1354
LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ
Sbjct: 1386 LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ 1445
Query: 1355 KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT 1414
KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT
Sbjct: 1446 KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT 1505
Query: 1415 LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT 1474
LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT
Sbjct: 1506 LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT 1565
Query: 1475 VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPI 1534
VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPI
Sbjct: 1566 VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPI 1625
Query: 1535 SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594
SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ
Sbjct: 1626 SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1685
Query: 1595 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWES 1654
TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWES
Sbjct: 1686 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWES 1745
Query: 1655 PQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPL 1714
PQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPL
Sbjct: 1746 PQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPL 1805
Query: 1715 IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS 1774
IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS
Sbjct: 1806 IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS 1865
Query: 1775 SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISW 1834
SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISW
Sbjct: 1866 SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISW 1925
Query: 1835 RTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP 1894
RTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP
Sbjct: 1926 RTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP 1985
Query: 1895 VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPG 1954
VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPG
Sbjct: 1986 VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPG 2045
Query: 1955 VTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVP 2014
VTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKK
Sbjct: 2046 VTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKK------------------------ 2081
Query: 2015 STVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPR 2074
TVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPR
Sbjct: 2082 -TVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPR 2140
Query: 2075 PYPPNVGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRG 2134
PYPPNVGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRG
Sbjct: 2141 PYPPNVGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRG 2200
Query: 2135 ATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMS 2194
ATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMS
Sbjct: 2201 ATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMS 2260
Query: 2195 ESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGE 2254
ESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGE
Sbjct: 2261 ESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGE 2320
Query: 2255 FKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGT 2314
FKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGT
Sbjct: 2321 FKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGT 2380
Query: 2315 TGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE 2355
TGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE
Sbjct: 2381 TGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE 2421
Score = 115 bits (287), Expect = 7e-25
Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)
Query: 2172 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2231
+++CFD YT + Y VGD +ER +S C C+G G G C + CH+ G +YKIG+
Sbjct: 94 EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
Query: 2232 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2287
W R E G M+ C CLGNGKGE+ C P C+D G +Y VGE W+K Y G +
Sbjct: 153 TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
Query: 2288 CTCFGGQRG 2296
CTC G G
Sbjct: 213 CTCLGEGSG 221
Score = 115 bits (287), Expect = 7e-25
Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)
Query: 94 EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
+++CFD YT + Y VGD +ER +S C C+G G G C + CH+ G +YKIG+
Sbjct: 2238 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2297
Query: 153 TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
W R E G M+ C CLGNGKGE+ C P C+D G +Y VGE W+K Y G +
Sbjct: 2298 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2353
Query: 213 CTCLGEGSG 221
CTC G G
Sbjct: 2354 CTCFGGQRG 2362
Score = 98.6 bits (244), Expect = 6e-20
Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)
Query: 2155 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2214
E V +GN E +P + CFD + Y VG+ WE+ + + C CLG GSG C
Sbjct: 166 ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
Query: 2215 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2260
S C+D +Y+IG+ W ++ G ++ C C GNG+GE+KC+ H
Sbjct: 226 TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
Query: 2261 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2292
A Y D G Y VG QW K CTC G
Sbjct: 286 FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
Score = 98.6 bits (244), Expect = 6e-20
Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)
Query: 166 ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
E V +GN E +P + CFD + Y VG+ WE+ + + C CLG GSG C
Sbjct: 2221 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2280
Query: 226 TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
S C+D +Y+IG+ W ++ G ++ C C GNG+GE+KC+ H
Sbjct: 2281 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2326
Query: 286 FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
A Y D G Y VG QW K CTC G
Sbjct: 2327 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2358
Score = 90.9 bits (224), Expect = 1e-17
Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)
Query: 2184 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2239
Y +GD+W++ + G + C C+G G G + C + D + + Y + + + ++ E
Sbjct: 478 YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
Query: 2240 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2296
G M++CTC G G+G +KCDP + C D G Y +G+ W+K G C C+G G
Sbjct: 538 GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
Query: 2297 WRC 2299
W C
Sbjct: 597 WHC 599
Score = 90.9 bits (224), Expect = 1e-17
Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)
Query: 478 YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
Y +GD+W++ + G + C C+G G G + C + D + + Y + + + ++ E
Sbjct: 2250 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2305
Query: 538 GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
G M++CTC G G+G +KCDP + C D G Y +G+ W+K G C C+G G
Sbjct: 2306 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2362
Query: 597 WHC 599
W C
Sbjct: 2363 WRC 2365
Score = 88.2 bits (217), Expect = 9e-17
Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)
Query: 2184 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2239
Y +GD W R E+G + L C CLG G G + C + C D+ G +Y +GE W++ +
Sbjct: 148 YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
Query: 2240 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2296
M+ CTCLG G G C D +T Y +G+ W +K+ G + C C G RG
Sbjct: 208 WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
Query: 2297 WRCD 2300
W+C+
Sbjct: 268 WKCE 271
Score = 88.2 bits (217), Expect = 9e-17
Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)
Query: 148 YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
Y +GD W R E+G + L C CLG G G + C + C D+ G +Y +GE W++ +
Sbjct: 2250 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2305
Query: 208 WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
M+ CTCLG G G C D +T Y +G+ W +K+ G + C C G RG
Sbjct: 2306 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2362
Query: 268 WKCE 271
W+C+
Sbjct: 2363 WRCD 2366
Score = 79.7 bits (195), Expect = 3e-14
Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)
Query: 2222 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2278
+ GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C + C D TY+V + +
Sbjct: 473 NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
Query: 2279 KEY-LGAICSCTCFGGQRG-WRCD 2300
K + G + +CTCFG RG W+CD
Sbjct: 533 KRHEEGHMLNCTCFGQGRGRWKCD 556
Score = 79.7 bits (195), Expect = 3e-14
Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)
Query: 473 NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
+ GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C + C D TY+V + +
Sbjct: 2288 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2344
Query: 533 KRHEEGHMLNCTCFGQGRGRWKCD 556
K + G + +CTCFG RG W+CD
Sbjct: 2345 KEY-LGAICSCTCFGGQRG-WRCD 2366
Score = 63.5 bits (153), Expect = 2e-09
Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)
Query: 2220 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2274
C+DNG +Y+I ++W+R G + CTC G +G F C+ E TC+D G TY VG
Sbjct: 52 CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
Query: 2275 EQWQKEYLGAICSCTCFGGQRG 2296
+ +++ I CTC G RG
Sbjct: 110 DTYERPKDSMIWDCTCIGAGRG 131
Score = 63.5 bits (153), Expect = 2e-09
Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)
Query: 52 CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
C+DNG +Y+I ++W+R G + CTC G +G F C+ E TC+D G TY VG
Sbjct: 2286 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2340
Query: 110 DTYERPKDSMIWDCTCIGAGRG 131
+ +++ I CTC G RG
Sbjct: 2341 EQWQKEYLGAICSCTCFGGQRG 2362
Score = 62.0 bits (149), Expect = 7e-09
Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)
Query: 2159 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2214
VGN E +Q D D T Y V D + + E G L C C G G G ++C
Sbjct: 499 VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
Query: 2215 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2259
D C D+ G Y+IG+ W++ +G C C G G GE+ C P
Sbjct: 556 DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
Score = 62.0 bits (149), Expect = 7e-09
Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)
Query: 499 VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
VGN E +Q D D T Y V D + + E G L C C G G G ++C
Sbjct: 2225 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2280
Query: 556 DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
D C D+ G Y+IG+ W++ +G C C G G GE+ C P
Sbjct: 2281 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2325
Score = 57.8 bits (138), Expect = 1e-07
Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 2264 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2323
CYD+GK Y + +QW++ YLG CTC+GG RG+ C++ +P E T Y +
Sbjct: 52 CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
Query: 2324 QR 2325
R
Sbjct: 106 YR 107
Score = 57.8 bits (138), Expect = 1e-07
Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 52 CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
CYD+GK Y + +QW++ YLG CTC+GG RG+ C++ +P E T Y +
Sbjct: 2330 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2389
Query: 106 YR 107
R
Sbjct: 2390 QR 2391
Score = 50.1 bits (118), Expect = 3e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)
Query: 2175 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2216
C D T + Y +GD W + G L C C G G G ++C+
Sbjct: 231 CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
Query: 2217 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2251
D+GV Y +G +W + N QM+ CTCLGNG
Sbjct: 291 AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
Score = 50.1 bits (118), Expect = 3e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)
Query: 231 CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
C D T + Y +GD W + G L C C G G G ++C+
Sbjct: 2241 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2282
Query: 291 AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
D+GV Y +G +W + N QM+ CTCLGNG
Sbjct: 2283 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2317
Score = 47.8 bits (112), Expect = 1e-04
Identities = 79/335 (23%), Positives = 121/335 (36%), Gaps = 69/335 (20%)
Query: 656 EATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGET 715
+ TI + SYTI GL+PG Y+ L ++ D ST+ SN T
Sbjct: 1949 QRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID---ASTAIDAPSNLRFLAT 2005
Query: 716 TPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPST---A 772
TP +S +VSW ++G+ ++YE + G P+ + +P
Sbjct: 2006 TP----------------NSLLVSWQPPRARITGYIIKYE--KPGSPPREV-VPRPRPGV 2046
Query: 773 TSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS 832
T I L PG +Y + V + + + ++ +T V T V
Sbjct: 2047 TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT-------------VQKTPFVTH-- 2091
Query: 833 RPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPV 892
GY + + LP T S QP V + I+ + +TP
Sbjct: 2092 ------PGY---------DTGNGIQLPGT------SGQQPSVGQQM-IFEEHGFRRTTP- 2128
Query: 893 VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQ 952
TT TP P P + + TI W P + + Y + PV E Q
Sbjct: 2129 ----PTTATPIRHR-PRPYPPNVGQEALSQTTISWAPFQD-TSEYIISCHPVGTDEEPLQ 2182
Query: 953 RLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESK 987
+T A +TGL+ G TY V A+ + K
Sbjct: 2183 FRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHK 2217
Score = 32.7 bits (73), Expect = 4.3
Identities = 29/126 (23%), Positives = 53/126 (42%), Gaps = 20/126 (15%)
Query: 2041 GQQPSV---GQQMIFEEHGFRR----------TTPPTTATPIRHRPRPYPPNVG-QEALS 2086
G +P V GQ + +++G + T+ P T+ + P+ P V E+++
Sbjct: 670 GLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVT 729
Query: 2087 QTT-----ISWAPFQDT-SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNII 2140
+ T +SW DT S + + +EP +P T+TS + L G Y +
Sbjct: 730 EITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVN 789
Query: 2141 VEALKD 2146
V + +
Sbjct: 790 VYQISE 795
>gi|47132547 fibronectin 1 isoform 7 preproprotein [Homo sapiens]
Length = 657
Score = 1440 bits (3728), Expect = 0.0
Identities = 647/647 (100%), Positives = 647/647 (100%)
Query: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
Query: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
Query: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
Query: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
Query: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
Query: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
Query: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
Query: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
Query: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
Query: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
Query: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRP 647
PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRP
Sbjct: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRP 647
Score = 115 bits (287), Expect = 7e-25
Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)
Query: 2172 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2231
+++CFD YT + Y VGD +ER +S C C+G G G C + CH+ G +YKIG+
Sbjct: 94 EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
Query: 2232 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2287
W R E G M+ C CLGNGKGE+ C P C+D G +Y VGE W+K Y G +
Sbjct: 153 TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
Query: 2288 CTCFGGQRG 2296
CTC G G
Sbjct: 213 CTCLGEGSG 221
Score = 98.6 bits (244), Expect = 6e-20
Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)
Query: 2155 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2214
E V +GN E +P + CFD + Y VG+ WE+ + + C CLG GSG C
Sbjct: 166 ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
Query: 2215 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2260
S C+D +Y+IG+ W ++ G ++ C C GNG+GE+KC+ H
Sbjct: 226 TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
Query: 2261 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2292
A Y D G Y VG QW K CTC G
Sbjct: 286 FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
Score = 90.9 bits (224), Expect = 1e-17
Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)
Query: 2184 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2239
Y +GD+W++ + G + C C+G G G + C + D + + Y + + + ++ E
Sbjct: 478 YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
Query: 2240 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2296
G M++CTC G G+G +KCDP + C D G Y +G+ W+K G C C+G G
Sbjct: 538 GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
Query: 2297 WRC 2299
W C
Sbjct: 597 WHC 599
Score = 88.2 bits (217), Expect = 9e-17
Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)
Query: 2184 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2239
Y +GD W R E+G + L C CLG G G + C + C D+ G +Y +GE W++ +
Sbjct: 148 YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
Query: 2240 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2296
M+ CTCLG G G C D +T Y +G+ W +K+ G + C C G RG
Sbjct: 208 WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
Query: 2297 WRCD 2300
W+C+
Sbjct: 268 WKCE 271
Score = 79.7 bits (195), Expect = 3e-14
Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)
Query: 2222 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2278
+ GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C + C D TY+V + +
Sbjct: 473 NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
Query: 2279 KEY-LGAICSCTCFGGQRG-WRCD 2300
K + G + +CTCFG RG W+CD
Sbjct: 533 KRHEEGHMLNCTCFGQGRGRWKCD 556
Score = 63.5 bits (153), Expect = 2e-09
Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)
Query: 2220 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2274
C+DNG +Y+I ++W+R G + CTC G +G F C+ E TC+D G TY VG
Sbjct: 52 CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
Query: 2275 EQWQKEYLGAICSCTCFGGQRG 2296
+ +++ I CTC G RG
Sbjct: 110 DTYERPKDSMIWDCTCIGAGRG 131
Score = 62.0 bits (149), Expect = 7e-09
Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)
Query: 2159 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2214
VGN E +Q D D T Y V D + + E G L C C G G G ++C
Sbjct: 499 VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
Query: 2215 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2259
D C D+ G Y+IG+ W++ +G C C G G GE+ C P
Sbjct: 556 DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
Score = 57.8 bits (138), Expect = 1e-07
Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 2264 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2323
CYD+GK Y + +QW++ YLG CTC+GG RG+ C++ +P E T Y +
Sbjct: 52 CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
Query: 2324 QR 2325
R
Sbjct: 106 YR 107
Score = 50.1 bits (118), Expect = 3e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)
Query: 2175 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2216
C D T + Y +GD W + G L C C G G G ++C+
Sbjct: 231 CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
Query: 2217 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2251
D+GV Y +G +W + N QM+ CTCLGNG
Sbjct: 291 AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
>gi|93141047 collagen, type XII, alpha 1 long isoform precursor [Homo
sapiens]
Length = 3063
Score = 383 bits (983), Expect = e-105
Identities = 357/1427 (25%), Positives = 593/1427 (41%), Gaps = 119/1427 (8%)
Query: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
+ W+ P + +Y++ + P G +E T+ G + ++GLK G
Sbjct: 832 LSWSGA-PGKVKQYLVTYTPVAG-GETQEVTVRGDTTNTVLQGLKEG------------- 876
Query: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVT-EITASSFVVSWVSASDT 746
T++ + T+ + + GE T + + VT +IT +S W SA
Sbjct: 877 -----TQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGM 931
Query: 747 VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTS 806
V G+RV ++ + + +LP A I +L P KY ++V+ GE + +
Sbjct: 932 VRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDA 991
Query: 807 QTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVT 866
T VD+ + ++ V W + YR+VY P G +P T S
Sbjct: 992 TTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTV 1051
Query: 867 LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
L LQP Y+IT+ + + E ++ +GT S SPR+L+ + T +
Sbjct: 1052 LKRLQPQTTYDITVLPIYKMGEGK----LRQGSGTTAS-RFKSPRNLKTSDPTMSSFRVT 1106
Query: 927 WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
W P V GY+V P G+ + + + L G TY VF + G ES
Sbjct: 1107 WEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGES 1166
Query: 987 KPLTAQQTTKLDAPTNLQFVN---------ETDSTVLV--RWTPPRAQITGYRLTVGLTR 1035
PL Q+ T L T + ++ E D +LV W+ RA R +
Sbjct: 1167 SPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRI- 1225
Query: 1036 RGQPRQYNVGPSVSKYPLRNLQ--PASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPP 1093
+++GP + L P +E+ ++ K + LQ +++P
Sbjct: 1226 ---VEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKS-----------LLQAVANLP- 1270
Query: 1094 YNTEVTETTIVITWTPAPRIGFKLGVRP--------------SQGGEAPREVTSDSG--- 1136
Y T T + + + + G+RP EAP + D G
Sbjct: 1271 YKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVEL 1330
Query: 1137 -----------SIVVSGLTPGVEYVYTI----QVLRDGQERDAPIVNKVVTP--LSPPTN 1179
+ + P + Y + + R + + N V P L P+N
Sbjct: 1331 FAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSN 1390
Query: 1180 LHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239
L + VSW + + Y++ P +G G E V ++S +L P
Sbjct: 1391 LVISERTHRS-FRVSWT-PPSDSVDRYKVEYYPVSG--GKRQEFYVSRMETSTVLKDLKP 1446
Query: 1240 GLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFL 1299
EY V+VY+V +D+ S P+ T P L ++GP TM V W P T ++
Sbjct: 1447 ETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGA--TGYI 1504
Query: 1300 VRYSPVKNEEDVA--ELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT- 1356
+ Y PVK+ E E+ + P+ N + LT+L+P TEY V+V +V S P+ R+ T
Sbjct: 1505 LSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTL 1564
Query: 1357 GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH-PEHFSGRPREDRVPHSRNSITL 1415
L P + D+T ++ V W + Y +R+ PE +E V S S +L
Sbjct: 1565 PLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEE---DVKEVEVDRSETSTSL 1621
Query: 1416 TNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVT 1474
+L T Y VS+ A++ ESP + Q++T P +L++ T +WD A
Sbjct: 1622 KDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASD 1681
Query: 1475 VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV----TGRGDSPAS 1530
V YRIT+ G +S E + G ++T L P Y +++ A+ + D S
Sbjct: 1682 VSLYRITWAPFG-SSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 1740
Query: 1531 SKPISINYRTEIDK--PSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTK 1588
+ + I T+ K P +QV + NS++VKW P+S V YR+T P G G +T
Sbjct: 1741 ERTLPI-LTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTT 1799
Query: 1589 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTDVDVDS 1647
T G Q + ++ L+P Y ++V + P GE + T ++ + L D +
Sbjct: 1800 TIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTST 1859
Query: 1648 IKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD 1707
+ + W+ +G +Y++ Y+ G EL P P G + A L+ L+P + YTV+VV ++
Sbjct: 1860 LNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIP-GNTNYAILRNLQPDTSYTVTVVPVYT 1918
Query: 1708 DMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMK 1766
+ + T T + +++ TP SL +W P + YRV +P + T P +
Sbjct: 1919 EGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSE 1978
Query: 1767 EINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDAT 1826
I + ++ V + L+ T Y V++ AL P+ TL S PR RV T
Sbjct: 1979 SIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPR-SGPRNLRVFGET 2037
Query: 1827 ETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTI-TGLQPGTDYKIYLYT 1885
+++++W + +++ P G + T P R+ I LQP T YKI +
Sbjct: 2038 TNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIA 2097
Query: 1886 LNDNARSSPVVIDAST-AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPP 1944
+ ++ + + T + P N+ VSW P + + GY I Y+ GS
Sbjct: 2098 VYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGS-- 2155
Query: 1945 REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT 1991
E + +T T+ L P T Y + V A ++ S PL + T
Sbjct: 2156 NEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTT 2202
Score = 334 bits (856), Expect = 7e-91
Identities = 325/1304 (24%), Positives = 551/1304 (42%), Gaps = 84/1304 (6%)
Query: 727 SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKY 786
S +E+T+ F +W A + V + + Y+ + DE ++ P+++TSV + L P Y
Sbjct: 639 SFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVE-PASSTSVVLSSLKPETLY 697
Query: 787 IVNVYQISEDGEQSLILSTSQTT--APDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIV 844
+VNV EDG S+ L+ +TT AP + V S + W++ + YRI+
Sbjct: 698 LVNVTAEYEDGF-SIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRII 756
Query: 845 YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
Y P G S E+ P TL +L P +Y +++ + TP+ TG +
Sbjct: 757 YRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPL------TGNAAT 810
Query: 905 DTV-PSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE 963
+ V +PRDL+ + T + + W+ V Y V PV G Q + + +T
Sbjct: 811 EEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV--AGGETQEVTVRGDTTNT 868
Query: 964 V-TGLSPGVTYYFKVFAVSHGRESKPLTAQQTT--KLDAPTNLQFVNETDSTVLVRWTPP 1020
V GL G Y V A+ L + TT + +P +L + TD+++ WT
Sbjct: 869 VLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSA 928
Query: 1021 RAQITGYRLT-VGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079
+ GYR++ L + N+ + NLQP ++Y +S+ A + E T
Sbjct: 929 PGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLT 988
Query: 1080 GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGVRP-SQGGEAPREVTSDSG 1136
G TT S E TE T+ +TW PAP + +++ RP +G + +V
Sbjct: 989 GDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVT 1048
Query: 1137 SIVVSGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
S V+ L P Y T+ + + G+ + + P NL ++P V+W
Sbjct: 1049 STVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLK-TSDPTMSSFRVTW 1107
Query: 1196 ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255
E ++ GY++T PT G E VV ++ + L G Y V+V+ + D E
Sbjct: 1108 E-PAPGEVKGYKVTFHPT-GDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGE 1165
Query: 1256 SVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAP-------PPSIDLTNFLVRYSPVKNE 1308
S P+ + + T + + G + + A SI NF S +
Sbjct: 1166 SSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRI 1225
Query: 1309 EDVAELSISPSDNAVVLTNLLPGTEYVVSV----SSVYEQHESTPLRGRQKTGLDSPTGI 1364
+V ++ A+ + P TE+ ++ S+ + + P +G ++ TG+
Sbjct: 1226 VEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGG-----NTLTGM 1280
Query: 1365 DFSDITANSF-TVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423
+ I +F T + PRA G I ++ + + E
Sbjct: 1281 ALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADE 1340
Query: 1424 YVVSIVALNGREESPLLIGQQSTVS--------------------DVPRDLEVVAATPTS 1463
+ ++A + + + ++S + P +L + T S
Sbjct: 1341 VELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRS 1400
Query: 1464 LLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTG 1523
+SW P+ +V Y++ Y G QEF V +++ + LKP +Y + VY+V
Sbjct: 1401 FRVSWTPPSDSVDRYKVEYYPVSGGKR-QEFYVSRMETSTVLKDLKPETEYVVNVYSVV- 1458
Query: 1524 RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPG 1583
S+P+ +T + + DV ++ V+W P TGY ++ P
Sbjct: 1459 ---EDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGG-ATGYILSYKPVKDTE 1514
Query: 1584 PTKTKTA--GPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-NIDRPKGLAF 1640
PT+ K GP +M + L P EY V+V A S+P+ VT + RP+ L
Sbjct: 1515 PTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKL 1574
Query: 1641 TDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTV 1700
DV ++ + WE G+V +Y V Y +PE+ + E+ D E + L+ L + YTV
Sbjct: 1575 RDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEV--EVDRSETSTSLKDLFSQTLYTV 1632
Query: 1701 SVVALHDDMESQPLIGTQST-AIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPK 1759
SV A+HD+ ES P+ ++T +PAPT+LK T+VT W ++ YR+ P
Sbjct: 1633 SVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPF 1692
Query: 1760 EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYAL-------KDTLTSRPAQGVVTTLE 1812
+ M+ I L D +++V L T YEVS+ A+ D + S ++TT
Sbjct: 1693 GSSDKMETI-LNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQA 1751
Query: 1813 NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQ-RTIKPDVRSYTIT 1871
S PR +V +AT ++T+ W + + +++ P+ G+ Q TI S +
Sbjct: 1752 PKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQ 1811
Query: 1872 GLQPGTDYKIYLYTLNDNARSSPVVIDAST-AIDAPSNLRFLATTPNSLLVSWQPPRARI 1930
L+P T Y I + +L + + T ++ NLR + ++L V W
Sbjct: 1812 KLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNP 1871
Query: 1931 TGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVI 1974
Y + Y P E+VP P A + L+P T YT+ V+
Sbjct: 1872 RQYKLFYAPAAGGPEELVPIP-GNTNYAILRNLQPDTSYTVTVV 1914
Score = 296 bits (757), Expect = 2e-79
Identities = 244/929 (26%), Positives = 413/929 (44%), Gaps = 43/929 (4%)
Query: 997 LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNL 1056
L+AP+NL T + V WTPP + Y++ G+ +++ V + L++L
Sbjct: 1385 LEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDL 1444
Query: 1057 QPASEYTVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTP-APRIG 1114
+P +EY V++ ++ ++ S G TL P S+ Y +V TT+ + W P G
Sbjct: 1445 KPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIY--DVGPTTMHVQWQPVGGATG 1502
Query: 1115 FKLGVRPSQGGEAPREVTSDSGSIV----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
+ L +P + E R G V ++ L P EY T+Q + + V +V
Sbjct: 1503 YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREV 1562
Query: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230
PL P +L L + + V WE P I T + +E V ++
Sbjct: 1563 TLPLPRPQDLKLR-DVTHSTMNVFWE--PVPGKVRKYIVRYKTPEEDVKEVE--VDRSET 1617
Query: 1231 SCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDTMRVTWA 1288
S + +L Y VSV V D+ ES P++ +T P VP PT+L+ T + + R TW
Sbjct: 1618 STSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRP-VPAPTNLKITEVTSEGFRGTWD 1676
Query: 1289 PPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHES 1347
S D++ + + ++P D E ++ +N +V NL P T Y VS++++Y ++ ES
Sbjct: 1677 HGAS-DVSLYRITWAPF-GSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESES 1734
Query: 1348 TPLRGRQKT--------GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSG 1399
L G ++T P + + T+NS TV W + YRI + P G
Sbjct: 1735 DDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEG 1794
Query: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVA 1458
+ + +NS+ L L P T Y +++ +L E + G+ T + R+L V
Sbjct: 1795 NEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYD 1854
Query: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
+ ++L + WD R Y++ Y G P + +PG+ + A + L+P YT+TV
Sbjct: 1855 PSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTVTV 1913
Query: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTP 1578
V GD +S R +QV + NS+ V+W P+ PV YRV +P
Sbjct: 1914 VPVYTEGDGGRTSDTGRTLMR---GLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSP 1970
Query: 1579 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTNIDRPKG 1637
+G P+++ + + +E L P Y V++ A GE P Q P+
Sbjct: 1971 VDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRN 2030
Query: 1638 LAFTDVDVDSIKIAWESPQGQVSRYRVTYS-SPEDGIHELFPAPDGEEDTAELQGLRPGS 1696
L +S+ +AW+ G V +YR+ YS + D I E P G + LQ L+P +
Sbjct: 2031 LRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVP-GRRNNVILQPLQPDT 2089
Query: 1697 EYTVSVVALHDDMESQPLIGT-QSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR 1755
Y ++V+A+++D + L G ++ + P ++ + T W P + GY++
Sbjct: 2090 PYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIV 2149
Query: 1756 VTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLE-NV 1814
P PM+ + +S + L +T Y+V+VYA D+ S P TTL NV
Sbjct: 2150 YKPVGSNEPMEA--FVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNV 2207
Query: 1815 SPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ 1874
+ + ++ T + W + T +++ PA+G + T++ S+ TGL
Sbjct: 2208 TDLKTYQI---GWDTFCVKW-SPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLS 2263
Query: 1875 PGTDYKIYLYTLNDNARSSPVVIDASTAI 1903
P TDY + ++ N V + T +
Sbjct: 2264 PDTDYGVTVFVQTPNLEGPGVSVKEHTTV 2292
Score = 276 bits (705), Expect = 2e-73
Identities = 253/942 (26%), Positives = 416/942 (44%), Gaps = 62/942 (6%)
Query: 1087 PGSSIPPYNTEVTETT---IVITWTPAPRI--GFKLGVRPSQGGEAPR-EVTSDSGSIVV 1140
PG P N ++E T ++WTP +K+ P GG+ V+ S V+
Sbjct: 1382 PGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVL 1441
Query: 1141 SGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199
L P EYV + V+ D E P+ T P +L++ D G T+ +
Sbjct: 1442 KDLKPETEYVVNVYSVVED--EYSEPLKGTEKTLPVPVVSLNIY---DVGPTTMHVQWQP 1496
Query: 1200 TPDITGYRITTTPTNGQQGNSLEEV-VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
TGY ++ P + +EV + + +L P EY V+V V D S P
Sbjct: 1497 VGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEP 1556
Query: 1259 IS--DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316
++ + +P +P P DL+ ++ TM V W P P + ++VRY EEDV E+ +
Sbjct: 1557 VTVREVTLP-LPRPQDLKLRDVTHSTMNVFWEPVPG-KVRKYIVRYKTP--EEDVKEVEV 1612
Query: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITANSFT 1375
S+ + L +L T Y VSVS+V+++ ES P+ ++ T + +PT + +++T+ F
Sbjct: 1613 DRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFR 1672
Query: 1376 VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGRE 1435
W + ++ YRI P S + E + N++ NL P T Y VSI A+ E
Sbjct: 1673 GTWDHGASDVSLYRITWAPFGSSDK-METILNGDENTLVFENLNPNTIYEVSITAIYPDE 1731
Query: 1436 -ESPLLIGQQSTVSDV--------PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETG 1486
ES LIG + T+ + PR+L+V AT SL + WD + V+ YRITY +
Sbjct: 1732 SESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPST 1791
Query: 1487 GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT-----GRGDSPASSKPISINYRTE 1541
G Q T+ G +++ + LKP YTITV ++ GR +KP++
Sbjct: 1792 GEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNT----- 1846
Query: 1542 IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG 1601
++V D ++++V+W + Y++ P G GP + + +
Sbjct: 1847 ---VRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRN 1902
Query: 1602 LQPTVEY---VVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQ 1658
LQP Y VV VY + G + +T + + R + + +S+ + W+ G
Sbjct: 1903 LQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR--NVQVYNPTPNSLDVRWDPAPGP 1960
Query: 1659 VSRYRVTYSSPEDGIH--ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIG 1716
V +YRV YS P DG E P G L+ L P + Y+V++VAL+ D E P
Sbjct: 1961 VLQYRVVYS-PVDGTRPSESIVVP-GNTRMVHLERLIPDTLYSVNLVALYSDGEGNPS-P 2017
Query: 1717 TQSTAIP--APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS 1774
Q +P P +L+ T SLS W + + YR+ +P P+ E P
Sbjct: 2018 AQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGR 2076
Query: 1775 -SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITIS 1833
++V++ L T Y+++V A+ + G T+ + PP+ ++D T +S
Sbjct: 2077 RNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV-GLLPPQNIHISDEWYTRFRVS 2135
Query: 1834 WRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSS 1893
W + G+++ P P++ + ++ SYT+ L P T Y + +Y D+ S
Sbjct: 2136 WDPSPSPVLGYKIVYKPVGSNEPMEAFVG-EMTSYTLHNLNPSTTYDVNVYAQYDSGLSV 2194
Query: 1894 PVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRP 1953
P+ +T ++L+ ++ V W P RA T Y +K P R R
Sbjct: 2195 PLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKL-SPADGTRGQEITVRG 2252
Query: 1954 GVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP 1995
T TGL P T+Y + V N + + ++ T P
Sbjct: 2253 SETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKP 2294
Score = 256 bits (655), Expect = 1e-67
Identities = 254/947 (26%), Positives = 393/947 (41%), Gaps = 51/947 (5%)
Query: 812 DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ 871
+AP + + + S V W+ P + Y++ Y P G E + S L DL+
Sbjct: 1386 EAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLK 1445
Query: 872 PGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE 931
P +Y + +Y+V E++ S P+ GT ++ VP L +V + + W P
Sbjct: 1446 PETEYVVNVYSVVEDEYSEPL------KGTEKTLPVPVV-SLNIYDVGPTTMHVQWQPVG 1498
Query: 932 SAVTGYRVDVIPV-----NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
A TGY + PV P E RL + N ++T L P Y V AV H S
Sbjct: 1499 GA-TGYILSYKPVKDTEPTRPKE--VRLGPTVNDM-QLTDLVPNTEYAVTVQAVLHDLTS 1554
Query: 987 KPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVG 1045
+P+T ++ T L P +L+ + T ST+ V W P ++ Y + T ++ V
Sbjct: 1555 EPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKY-IVRYKTPEEDVKEVEVD 1613
Query: 1046 PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105
S + L++L + YTVS+ A+ ESP T TT + TEVT
Sbjct: 1614 RSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRG 1673
Query: 1106 TWTPAPRIGFKLGVRPSQGGEAPREVT---SDSGSIVVSGLTPGVEYVYTIQVLRD---- 1158
TW + + G + + T D ++V L P Y +I +
Sbjct: 1674 TWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESE 1733
Query: 1159 -----GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT 1213
G ER PI+ P S P NL + N + LTV W+ + + YRIT P+
Sbjct: 1734 SDDLIGSERTLPILT-TQAPKSGPRNLQV-YNATSNSLTVKWD-PASGRVQKYRITYQPS 1790
Query: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDT-IIPAVPPPTD 1272
G +GN + Q+S L P Y ++V ++ D E ++ + +
Sbjct: 1791 TG-EGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRN 1849
Query: 1273 LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332
LR + T+ V W + + + Y+P + + I + N +L NL P T
Sbjct: 1850 LRVYDPSTSTLNVRWDHAEG-NPRQYKLFYAPAAGGPEEL-VPIPGNTNYAILRNLQPDT 1907
Query: 1333 EYVVSVSSVYEQHESTPLRGRQKTGLDS-PTGIDFSDITANSFTVHWIAPRATITGYRIR 1391
Y V+V VY + + +T + + + T NS V W + YR+
Sbjct: 1908 SYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVV 1967
Query: 1392 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSDV 1450
+ P + VP + + L L P T Y V++VAL + E +P ++
Sbjct: 1968 YSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSG 2027
Query: 1451 PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEF-TVPGSKSTATISGLK 1509
PR+L V T SL ++WD V+ YRI Y T G+ P+ E+ TVPG ++ + L+
Sbjct: 2028 PRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGRRNNVILQPLQ 2086
Query: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRT-EIDKPSQMQVTDVQDNSISVKWLPSSSP 1568
P Y ITV AV GD ++ N RT + P + ++D V W PS SP
Sbjct: 2087 PDTPYKITVIAVYEDGD----GGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSP 2142
Query: 1569 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628
V GY++ P P + + T T+ L P+ Y V+VYAQ SG S PL
Sbjct: 2143 VLGYKIVYKPVGSNEPMEAFVG--EMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQG 2200
Query: 1629 VTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE 1688
T L + D+ + W SP + YR+ SP DG G E +
Sbjct: 2201 TTLYLNVTDLKTYQIGWDTFCVKW-SPHRAATSYRLKL-SPADGTRGQEITVRGSETSHC 2258
Query: 1689 LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTP 1735
GL P ++Y V+V ++E P + + PT+ TP
Sbjct: 2259 FTGLSPDTDYGVTVFVQTPNLEG-PGVSVKEHTTVKPTEAPTEPPTP 2304
Score = 219 bits (559), Expect = 2e-56
Identities = 236/938 (25%), Positives = 396/938 (42%), Gaps = 77/938 (8%)
Query: 1266 AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1325
A PP DL F+ + + W+P ++ ++ + Y +++V + + S +VVL
Sbjct: 631 AYVPPKDLSFSEVTSYGFKTNWSPAGE-NVFSYHITYKEAAGDDEVTVVEPA-SSTSVVL 688
Query: 1326 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRA 1383
++L P T Y+V+V++ YE S PL G + T +P + +D T +SF + W
Sbjct: 689 SSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPG 748
Query: 1384 TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQ 1443
+ YRI + P G RE P ++ TL NL P T+Y VS++ L G
Sbjct: 749 RVLRYRIIYRPVA-GGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGN 807
Query: 1444 QST--VSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS 1501
+T V PRDL V T +++ +SW V+ Y +TY G QE TV G +
Sbjct: 808 AATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGE-TQEVTVRGDTT 866
Query: 1502 TATISGLKPGVDYTITVYAV--TGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS 1559
+ GLK G Y ++V A+ +G GD+ E P + D+ D SI
Sbjct: 867 NTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTL----EERGSPQDLVTKDITDTSIG 922
Query: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619
W + V GYRV+ T K D IE LQP +Y +SV+A SG
Sbjct: 923 AYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSG 982
Query: 1620 ESQPLVQTAVTNIDR-PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFP 1678
E +PL A T + + K L + +++++ W+ G+V YRV Y G +
Sbjct: 983 EGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAK 1042
Query: 1679 APDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA--IPAPTDLKFTQVTPT 1736
P T L+ L+P + Y ++V+ ++ E + G+ +TA +P +LK + T +
Sbjct: 1043 VPPTVTSTV-LKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMS 1101
Query: 1737 SLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1796
S W P ++ GY+V P + E+ + P ++VV+ L T Y+V+V+ +
Sbjct: 1102 SFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMF 1161
Query: 1797 DTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAV-PANGQT 1855
D S P G +T ++TT+ + E +T + D V +G
Sbjct: 1162 DGGESSPLVG-------------QEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSW 1208
Query: 1856 PIQRTIKPDVRSYTITGLQPGTDY--KIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLA 1913
I R VRS+ I+ + D K L + + D S L+ +A
Sbjct: 1209 SIGRANFRTVRSF-ISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVA 1267
Query: 1914 TTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYV 1973
P +TG + + + + + RPR IT + +
Sbjct: 1268 NLP-------YKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPS 1320
Query: 1974 IALKNNQKSEPLIGRKKTDELP-QLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGN 2032
LK+ IG K DE+ +++ + H + D S + +T + N
Sbjct: 1321 KKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLT---INLCN 1377
Query: 2033 GIQLPGTSGQQPSVGQQMIFEE---HGFRRTTPPTTATPIRHRPRPYPPNVGQE-----A 2084
++ PG + PS ++ E FR + P + + R++ YP + G+ +
Sbjct: 1378 SVKGPGDL-EAPS---NLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVS 1433
Query: 2085 LSQTTISWAPFQDTSEYIISCHPVGTDE--EPLQ-----FRVPGTSTSATLTGLTR---- 2133
+T+ + +EY+++ + V DE EPL+ VP S + G T
Sbjct: 1434 RMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQ 1493
Query: 2134 -----GAT-YNIIVEALKDQQRHKVREEVVTVGNSVNE 2165
GAT Y + + +KD + + +E V +G +VN+
Sbjct: 1494 WQPVGGATGYILSYKPVKDTEPTRPKE--VRLGPTVND 1529
Score = 200 bits (508), Expect = 2e-50
Identities = 217/866 (25%), Positives = 356/866 (41%), Gaps = 75/866 (8%)
Query: 623 PNSHPIQWNAPQP-SHISKYILRWRPKNSVG--RWKEATIPGHLNSYTIKGLKPGVVYEG 679
P + +QW QP + YIL ++P R KE + +N + L P Y
Sbjct: 1487 PTTMHVQW---QPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYA- 1542
Query: 680 QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE-SVTEITASSFVV 738
+++Q H TS PVT VT PL + + ++T S+ V
Sbjct: 1543 --VTVQAVLHD----------LTSEPVTVREVT------LPLPRPQDLKLRDVTHSTMNV 1584
Query: 739 SWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798
W V + V Y+ EE + +D T+TS+ DL Y V+V + ++GE
Sbjct: 1585 FWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLK--DLFSQTLYTVSVSAVHDEGE 1642
Query: 799 QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858
+ + T AP + + +V W + ++ YRI ++P E L
Sbjct: 1643 SPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETIL 1702
Query: 859 PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE------TTGTPRSDTVPSPRD 912
N++ +L P Y ++I A+ ++ + +I E TT P+S PR+
Sbjct: 1703 NGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKS----GPRN 1758
Query: 913 LQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVT 972
LQ T +T+ W P V YR+ P G R + L P
Sbjct: 1759 LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 1818
Query: 973 YYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031
Y V ++ E +T + TK L+ NL+ + + ST+ VRW Y+L
Sbjct: 1819 YTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFY 1878
Query: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG--S 1089
G + + + LRNLQP + YTV++V + + + + TL G
Sbjct: 1879 APAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR 1938
Query: 1090 SIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSG------- 1142
++ YN T ++ + W PAP + V S P + T S SIVV G
Sbjct: 1939 NVQVYNP--TPNSLDVRWDPAPGPVLQYRVVYS-----PVDGTRPSESIVVPGNTRMVHL 1991
Query: 1143 --LTPGVEY-VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199
L P Y V + + DG+ +P + + P S P NL + T L+V+W+ +
Sbjct: 1992 ERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL-PRSGPRNLRV-FGETTNSLSVAWDHAD 2049
Query: 1200 TPDITGYRITTTPTNGQQGNSLEE--VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257
P + YRI +PT G+ ++E V +++ L P Y ++V V +D +
Sbjct: 2050 GP-VQQYRIIYSPT---VGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGG 2105
Query: 1258 PIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316
++ + + PP ++ ++ RV+W P PS + + + Y PV + E + +
Sbjct: 2106 HLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPS-PVLGYKIVYKPVGSNEPME--AF 2162
Query: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTV 1376
+ L NL P T Y V+V + Y+ S PL + T + T + I ++F V
Sbjct: 2163 VGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCV 2222
Query: 1377 HWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436
W +P T YR++ P R +E V S S T L+P T+Y V++ E
Sbjct: 2223 KW-SPHRAATSYRLKLSPAD-GTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLE 2280
Query: 1437 SP-LLIGQQSTVSDVPRDLEVVAATP 1461
P + + + +TV P + TP
Sbjct: 2281 GPGVSVKEHTTVK--PTEAPTEPPTP 2304
Score = 194 bits (492), Expect = 1e-48
Identities = 209/874 (23%), Positives = 361/874 (41%), Gaps = 76/874 (8%)
Query: 905 DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAE 963
+ V P +L +EV+ V + W P S VTGY+V + P+ G L + + T
Sbjct: 332 EVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT-AGSRQHALSVGPQTTTLS 390
Query: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK-----------LDAPTNLQF-VNETDS 1011
V LS Y V A+ S+P++ + T+ +D ++ F V+ + S
Sbjct: 391 VRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYS 450
Query: 1012 TVLVRWTPPRA---------QITGYRLTVGL-----------TRRGQPRQYNVGPSVSKY 1051
+ + RA +I+ R+ + L T + + ++ +++ +
Sbjct: 451 IGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTF 510
Query: 1052 PLR----NLQPASEYTVSLVAI--KGNQES-PKATGVFTTLQPGSSIPPYNTEVTETTIV 1104
P R N A Y + + KG++ + PK + T + + ++ + +
Sbjct: 511 PYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVE 570
Query: 1105 ITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164
I +G K VR A + ++ + + T + ++ A
Sbjct: 571 IF-----AVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELA 625
Query: 1165 PIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEV 1224
I K P P +L G T +W ++ Y IT G + + V
Sbjct: 626 AIKKKAYVP---PKDLSFSEVTSYGFKT-NWS-PAGENVFSYHITYKEAAGD--DEVTVV 678
Query: 1225 VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDT 1282
A +S +L P Y V+V +D S+P++ +T P +L+ T+ D+
Sbjct: 679 EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDS 738
Query: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY 1342
++TW P + + + Y PV E E++ P+ L NL+P T+Y VSV Y
Sbjct: 739 FKITWTQAPG-RVLRYRIIYRPVAGGES-REVTTPPNQRRRTLENLIPDTKYEVSVIPEY 796
Query: 1343 EQHESTPLRGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGR 1400
TPL G T +P + SD T ++ + W + Y + + P G
Sbjct: 797 FSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV-AGGE 855
Query: 1401 PREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSD--VPRDLEVVA 1458
+E V + L L GT+Y +S+ AL L G+ +T+ + P+DL
Sbjct: 856 TQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKD 915
Query: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
T TS+ W + VR YR+++ + E +P I L+P Y I+V
Sbjct: 916 ITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISV 975
Query: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQ-MQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577
+A G+ +P++ + TE+ + S+ ++V + +N++ V W P+ V YRV
Sbjct: 976 FATYSSGE----GEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYR 1031
Query: 1578 PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR--- 1634
P +G G P T ++ LQP Y ++V GE + L Q + T R
Sbjct: 1032 P-HGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGK-LRQGSGTTASRFKS 1089
Query: 1635 PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDG--IHELFPAPDGEEDTAELQGL 1692
P+ L +D + S ++ WE G+V Y+VT+ D + EL P ++T L+ L
Sbjct: 1090 PRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGP--YDNTVVLEEL 1147
Query: 1693 RPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT 1726
R G+ Y V+V + D ES PL+G + T + T
Sbjct: 1148 RAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTT 1181
Score = 170 bits (430), Expect = 2e-41
Identities = 178/759 (23%), Positives = 310/759 (40%), Gaps = 73/759 (9%)
Query: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326
V PP++L + +++ W P PS +T + V +P+ LS+ P + +
Sbjct: 334 VEPPSNLIAMEVSSKYVKLNWNPSPS-PVTGYKVILTPMTAGSRQHALSVGPQTTTLSVR 392
Query: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKT-----------GLDSPTGIDFSDITANSFT 1375
+L TEY +SVS++ S P+ +KT G+D I F + S++
Sbjct: 393 DLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVF--LVDGSYS 450
Query: 1376 V---HWIAPRA----TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSI 1428
+ +++ RA + + I + S + R PH+ TL T + + +I
Sbjct: 451 IGIANFVKVRAFLEVLVKSFEISPNRVQIS-LVQYSRDPHT--EFTLKKFTKVEDIIEAI 507
Query: 1429 VALNGREES------------PLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVR 1476
R S + + + + S+VP+ + ++ +S ++ PA+ +R
Sbjct: 508 NTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSS--DAFRDPAIKLR 565
Query: 1477 YYRITYGETGGNSPVQEFTV---PGSKSTATISGLKPGVDYTITVYAVTG-RGDSPASSK 1532
NS V+ F V +S P + TV + S ++
Sbjct: 566 -----------NSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQ 614
Query: 1533 PISINYRTEID--------KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGP 1584
I + E+ P + ++V W P+ V Y +T K G
Sbjct: 615 SICLRIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSYHITY--KEAAGD 672
Query: 1585 TKTKTAGP-DQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR--PKGLAFT 1641
+ P T + + L+P Y+V+V A+ G S PL T + P+ L T
Sbjct: 673 DEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVT 732
Query: 1642 DVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVS 1701
D DS KI W G+V RYR+ Y G P + L+ L P ++Y VS
Sbjct: 733 DETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQR-RRTLENLIPDTKYEVS 791
Query: 1702 VVALHDDMESQPLIGTQST--AIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPK 1759
V+ + PL G +T P DL+ + T +++ W+ ++ Y V TP
Sbjct: 792 VIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTP- 850
Query: 1760 EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRR 1819
G +E+ + D+++ V+ GL T+Y +SV AL + G TTLE P+
Sbjct: 851 VAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQD 910
Query: 1820 ARVTDATETTITISWRTKTETITGFQVDAVPANGQTPI-QRTIKPDVRSYTITGLQPGTD 1878
D T+T+I W + + G++V ++ + D I LQP T
Sbjct: 911 LVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETK 970
Query: 1879 YKIYLYTLNDNARSSPVVIDASTAIDAPS-NLRFLATTPNSLLVSWQPPRARITGYIIKY 1937
Y+I ++ + P+ DA+T + S L+ T N++ V+W+P ++ Y + Y
Sbjct: 971 YRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVY 1030
Query: 1938 EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL 1976
+P +++V + P VT + L+P T Y I V+ +
Sbjct: 1031 -RPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPI 1068
Score = 161 bits (407), Expect = 8e-39
Identities = 155/582 (26%), Positives = 252/582 (43%), Gaps = 30/582 (5%)
Query: 885 ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPV 944
E +S + I+QE + VP P+DL F EVT W+P V Y +
Sbjct: 611 ELTQSICLRIEQELAAIKKKAYVP-PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEA 669
Query: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK--LDAPTN 1002
E P S +T ++ L P Y V A S PL ++TT+ AP N
Sbjct: 670 AGDDEVTVVEPAS-STSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRN 728
Query: 1003 LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEY 1062
L+ +ET + + WT ++ YR+ G+ R+ P+ + L NL P ++Y
Sbjct: 729 LKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKY 788
Query: 1063 TVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGV 1119
VS++ + TG T + G+ ++ T +T+ ++W+ AP + +
Sbjct: 789 EVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTY 848
Query: 1120 RPSQGGEAPREVT--SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPI-VNKVVTPLSP 1176
P GGE +EVT D+ + V+ GL G +Y ++ L DA +
Sbjct: 849 TPVAGGET-QEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGS 907
Query: 1177 PTNLHLEANPDTGVLTVSWERSTTPDITGYRIT----TTPTNGQQGNSLEEVVHADQSSC 1232
P +L + DT + ++ S + GYR++ + + N E+ +H
Sbjct: 908 PQDLVTKDITDTSI--GAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHT----- 960
Query: 1233 TFDNLSPGLEYNVSVYTVKDDKESVPIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPP 1291
+NL P +Y +SV+ E P++ D L+ +TMRVTW P P
Sbjct: 961 MIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAP 1020
Query: 1292 SIDLTNFLVRYSP-VKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPL 1350
+ N+ V Y P + ++ VA+ + P+ + VL L P T Y ++V +Y+ E
Sbjct: 1021 G-KVVNYRVVYRPHGRGKQMVAK--VPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLR 1077
Query: 1351 RGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH 1408
+G T SP + SD T +SF V W + GY++ HP R E V
Sbjct: 1078 QGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGP 1137
Query: 1409 SRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSD 1449
N++ L L GT Y V++ + +G E SPL+ + +T+SD
Sbjct: 1138 YDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSD 1179
Score = 155 bits (391), Expect = 6e-37
Identities = 153/655 (23%), Positives = 255/655 (38%), Gaps = 48/655 (7%)
Query: 636 SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695
S +S Y + W P S + E + G N+ + L P +YE +SI E
Sbjct: 1680 SDVSLYRITWAPFGSSDKM-ETILNGDENTLVFENLNPNTIYE---VSITAIYPDESESD 1735
Query: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
D + + P+ TT + V T++S V W AS V +R+ Y+
Sbjct: 1736 DLIGSERTLPIL-------TTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQ 1788
Query: 756 LSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP 815
S Q + SV + L P Y + V + DGE + +T +
Sbjct: 1789 PSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVR 1848
Query: 816 DPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQ 875
+ V +++ VRW + Y++ Y+P+ G + +P N L +LQP
Sbjct: 1849 NLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTS 1908
Query: 876 YNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVT 935
Y +T+ V + T+ T R+ R++Q T + + W P V
Sbjct: 1909 YTVTVVPVYTEGDG------GRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVL 1962
Query: 936 GYRVDVIPVNLPGEHGQRLPISRNT-FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ-Q 993
YRV PV+ + + + NT + L P Y + A+ E P AQ +
Sbjct: 1963 QYRVVYSPVD-GTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGR 2021
Query: 994 TTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS-VSKYP 1052
T P NL+ ET +++ V W + YR+ T +Y P +
Sbjct: 2022 TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVI 2081
Query: 1053 LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTE---TTIVITW-- 1107
L+ LQP + Y ++++A+ + + TG T+ +PP N +++ T ++W
Sbjct: 2082 LQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV---GLLPPQNIHISDEWYTRFRVSWDP 2138
Query: 1108 TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167
+P+P +G+K+ +P E + S + L P Y + D P+
Sbjct: 2139 SPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYD-SGLSVPLT 2197
Query: 1168 NKVVTPLSPPTNLH-LEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVH 1226
++ T T+L + DT V W S T YR+ +P +G +G E V
Sbjct: 2198 DQGTTLYLNVTDLKTYQIGWDT--FCVKW--SPHRAATSYRLKLSPADGTRGQ--EITVR 2251
Query: 1227 ADQSSCTFDNLSPGLEYNVSVY-----------TVKDDKESVPISDTIIPAVPPP 1270
++S F LSP +Y V+V+ +VK+ P P PPP
Sbjct: 2252 GSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPP 2306
Score = 147 bits (370), Expect = 2e-34
Identities = 135/576 (23%), Positives = 230/576 (39%), Gaps = 26/576 (4%)
Query: 798 EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELN 857
EQ L + P P D + +V WS + Y I Y + +
Sbjct: 621 EQELAAIKKKAYVP--PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVV 678
Query: 858 LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE 917
P ++ SV LS L+P Y + + A E+ S P+ ++ T + +PR+L+ +
Sbjct: 679 EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETT-----EEVKGAPRNLKVTD 733
Query: 918 VTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
T I WT V YR+ PV GE + + L P Y V
Sbjct: 734 ETTDSFKITWTQAPGRVLRYRIIYRPV-AGGESREVTTPPNQRRRTLENLIPDTKYEVSV 792
Query: 978 FAVSHGRESKPLTAQQTTK--LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTR 1035
PLT T+ P +L+ + T ST+ + W+ ++ Y +T
Sbjct: 793 IPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVA 852
Query: 1036 RGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQP-GSSIPPY 1094
G+ ++ V + L+ L+ ++Y +S+ A+ + G TTL+ GS
Sbjct: 853 GGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLV 912
Query: 1095 NTEVTETTIVITWTPAP------RIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
++T+T+I WT AP R+ +K GE + + D+ ++ L P +
Sbjct: 913 TKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGE--KNLPEDAIHTMIENLQPETK 970
Query: 1149 YVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRI 1208
Y ++ E + P+ T LS + + V+W + + YR+
Sbjct: 971 YRISVFATYSSGEGE-PLTGDATTELSQDSKTLKVDEETENTMRVTW-KPAPGKVVNYRV 1028
Query: 1209 TTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV--PISDTIIPA 1266
P +G + V +S L P Y+++V + E S T
Sbjct: 1029 VYRPHG--RGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASR 1086
Query: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326
P +L+ ++ + RVTW P P ++ + V + P ++ + EL + P DN VVL
Sbjct: 1087 FKSPRNLKTSDPTMSSFRVTWEPAPG-EVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLE 1145
Query: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1362
L GT Y V+V +++ ES+PL G++ T L T
Sbjct: 1146 ELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTT 1181
Score = 105 bits (262), Expect = 5e-22
Identities = 125/491 (25%), Positives = 193/491 (39%), Gaps = 26/491 (5%)
Query: 1712 QPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLA 1771
Q L + A P DL F++VT W+P + Y +T KE G + +
Sbjct: 622 QELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSY--HITYKEAAGDDEVTVVE 679
Query: 1772 PDSS-SVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1830
P SS SVV+S L T Y V+V A + S P G TT E PR +VTD T +
Sbjct: 680 PASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSF 739
Query: 1831 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1890
I+W + +++ P G + T P+ R T+ L P T Y++ + +
Sbjct: 740 KITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSG 799
Query: 1891 RSSPVVIDAST--AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEK-PGSPPREV 1947
+P+ +A+T P +LR T +++ +SW ++ Y++ Y G +EV
Sbjct: 800 PGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEV 859
Query: 1948 VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDE---LPQ-LVTLPHP 2003
R T + GL+ GT+Y + V AL + + L G T E PQ LVT
Sbjct: 860 T--VRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDIT 917
Query: 2004 NLH-GPEILDVPSTVQKTPFVTHPGY---DTGNGIQLPGTS------GQQPSVGQQM-IF 2052
+ G P V+ Y DTG LP + QP ++ +F
Sbjct: 918 DTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEK-NLPEDAIHTMIENLQPETKYRISVF 976
Query: 2053 EEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQ-DTSEYIISCHPVGTD 2111
+ P T V +E + ++W P Y + P G
Sbjct: 977 ATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRG 1036
Query: 2112 EEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPT 2171
++ + +VP T TS L L TY+I V + K+R+ T + N T
Sbjct: 1037 KQ-MVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKT 1095
Query: 2172 DDSCFDPYTVS 2182
D + V+
Sbjct: 1096 SDPTMSSFRVT 1106
Score = 85.9 bits (211), Expect = 4e-16
Identities = 99/497 (19%), Positives = 183/497 (36%), Gaps = 61/497 (12%)
Query: 1542 IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG 1601
++ PS + +V + + W PS SPVTGY+V TP + GP T +++
Sbjct: 334 VEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRD 393
Query: 1602 LQPTVEYVVSVYAQNPSGESQPL-----VQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQ 1656
L EY +SV A S+P+ Q ++ +G+ D+ D + + S
Sbjct: 394 LSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGV---DIKADIVFLVDGSYS 450
Query: 1657 GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDD----MESQ 1712
++ + + E + +P+ + + P +E+T+ +D + +
Sbjct: 451 IGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTF 510
Query: 1713 PLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE--INL 1770
P G + A T ++ P+ S P + +T + + ++ I L
Sbjct: 511 PYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPK------VMILITDGKSSDAFRDPAIKL 564
Query: 1771 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVS--------------- 1815
+ G+ A + E+ + + S PA+ V T+E+
Sbjct: 565 RNSDVEIFAVGVKDAVRSEL------EAIASPPAETHVFTVEDFDAFQRISFELTQSICL 618
Query: 1816 ---------------PPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT 1860
PP+ ++ T +W E + + + A G +
Sbjct: 619 RIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVV 678
Query: 1861 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST--AIDAPSNLRFLATTPNS 1918
S ++ L+P T Y + + ++ S P+ + +T AP NL+ T +S
Sbjct: 679 EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDS 738
Query: 1919 LLVSWQPPRARITGYIIKYEK-PGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALK 1977
++W R+ Y I Y G REV P T+ L P T+Y + VI
Sbjct: 739 FKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQ--RRRTLENLIPDTKYEVSVIPEY 796
Query: 1978 NNQKSEPLIGRKKTDEL 1994
+ PL G T+E+
Sbjct: 797 FSGPGTPLTGNAATEEV 813
Score = 76.6 bits (187), Expect = 3e-13
Identities = 84/359 (23%), Positives = 144/359 (40%), Gaps = 55/359 (15%)
Query: 1813 NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITG 1872
++ P +++ T + +SW ++++ ++V+ P +G + + S +
Sbjct: 1384 DLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKD 1443
Query: 1873 LQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITG 1932
L+P T+Y + +Y++ ++ S P+ T +L P ++ V WQP TG
Sbjct: 1444 LKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGA-TG 1502
Query: 1933 YIIKYE--KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKK 1990
YI+ Y+ K P R R P V + +T L P TEY + V A+ ++ SEP+ R+
Sbjct: 1503 YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVRE- 1561
Query: 1991 TDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPG--------YDT-GNGIQLPGTSG 2041
VTLP P ++ DV + + PG Y T ++
Sbjct: 1562 -------VTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDR 1614
Query: 2042 QQPSVGQQMIFEEHGF---------RRTTPPTTATPIRHRPRPYPPNV------------ 2080
+ S + +F + + +PP TA RP P P N+
Sbjct: 1615 SETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETT-RPVPAPTNLKITEVTSEGFRG 1673
Query: 2081 ----GQEALSQTTISWAPF--QDTSEYIISCHPVGTDEEPLQFR--VPGTSTSATLTGL 2131
G +S I+WAPF D E I++ DE L F P T ++T +
Sbjct: 1674 TWDHGASDVSLYRITWAPFGSSDKMETILN-----GDENTLVFENLNPNTIYEVSITAI 1727
Score = 66.6 bits (161), Expect = 3e-10
Identities = 37/123 (30%), Positives = 64/123 (52%), Gaps = 4/123 (3%)
Query: 800 SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP 859
+L+LS+ + D P D +D+ ++ + W++P PI GYRI P+ +G + E L
Sbjct: 15 ALLLSSIEAEV-DPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLS 73
Query: 860 ETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ---QETTGTPRSDTVPSPRDLQFV 916
+ LS+L P +Y +TI + +E +ES PV+ Q Q + T + P ++Q
Sbjct: 74 ASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKC 133
Query: 917 EVT 919
V+
Sbjct: 134 SVS 136
Score = 59.7 bits (143), Expect = 3e-08
Identities = 28/85 (32%), Positives = 44/85 (51%), Gaps = 1/85 (1%)
Query: 1541 EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1600
E+D PS + + +N++ + W P+ GYR+T P GPTK T TE +
Sbjct: 24 EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLS 82
Query: 1601 GLQPTVEYVVSVYAQNPSGESQPLV 1625
L P EYVV++ + + ES P++
Sbjct: 83 ELVPETEYVVTITSYDEVEESVPVI 107
Score = 58.9 bits (141), Expect = 6e-08
Identities = 37/117 (31%), Positives = 59/117 (50%), Gaps = 5/117 (4%)
Query: 996 KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN 1055
++D P++L F ++TV + W P I GYR+TV T G +++ + S ++ L
Sbjct: 24 EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSE 83
Query: 1056 LQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI----VITWT 1108
L P +EY V++ + +ES G T+Q GSS P + +T I V WT
Sbjct: 84 LVPETEYVVTITSYDEVEESVPVIGQL-TIQTGSSTKPVEKKPGKTEIQKCSVSAWT 139
Score = 53.5 bits (127), Expect = 2e-06
Identities = 29/87 (33%), Positives = 48/87 (55%), Gaps = 2/87 (2%)
Query: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326
V PP+DL F I +T+ ++WA P + + + P + E ++S S +L+
Sbjct: 25 VDPPSDLNFKIIDENTVHMSWAKPVD-PIVGYRITVDPT-TDGPTKEFTLSASTTETLLS 82
Query: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGR 1353
L+P TEYVV+++S E ES P+ G+
Sbjct: 83 ELVPETEYVVTITSYDEVEESVPVIGQ 109
Score = 50.1 bits (118), Expect = 3e-05
Identities = 35/125 (28%), Positives = 58/125 (46%), Gaps = 7/125 (5%)
Query: 1624 LVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE 1683
L+ + +D P L F +D +++ ++W P + YR+T DG + F
Sbjct: 17 LLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSAST 76
Query: 1684 EDTAELQGLRPGSEYTVSVVALHDDMESQPLIG-----TQSTAIPAPTDLKFTQVTPTSL 1738
+T L L P +EY V++ + + ES P+IG T S+ P T++ S+
Sbjct: 77 TETL-LSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKCSV 135
Query: 1739 SAQWT 1743
SA WT
Sbjct: 136 SA-WT 139
Score = 50.1 bits (118), Expect = 3e-05
Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 1/86 (1%)
Query: 1358 LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
+D P+ ++F I N+ + W P I GYRI P G +E + S L+
Sbjct: 25 VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83
Query: 1418 LTPGTEYVVSIVALNGREESPLLIGQ 1443
L P TEYVV+I + + EES +IGQ
Sbjct: 84 LVPETEYVVTITSYDEVEESVPVIGQ 109
Score = 48.9 bits (115), Expect = 6e-05
Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 1/96 (1%)
Query: 1714 LIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD 1773
L+ + + P+DL F + ++ W P + GYR+ V P GP KE L+
Sbjct: 17 LLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDP-TTDGPTKEFTLSAS 75
Query: 1774 SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT 1809
++ ++S L+ T+Y V++ + + S P G +T
Sbjct: 76 TTETLLSELVPETEYVVTITSYDEVEESVPVIGQLT 111
Score = 47.8 bits (112), Expect = 1e-04
Identities = 29/117 (24%), Positives = 56/117 (47%), Gaps = 5/117 (4%)
Query: 1700 VSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPK 1759
+S V D + L+ + P P++L +V+ + W P +TGY+V +TP
Sbjct: 313 ISQVCSGVDEQLGELVSGEEVVEP-PSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPM 371
Query: 1760 EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSP 1816
+++ P ++++ V L T+Y++SV A+K +S P ++ +E P
Sbjct: 372 TAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEP----ISIMEKTQP 424
Score = 45.1 bits (105), Expect = 8e-04
Identities = 28/96 (29%), Positives = 49/96 (51%), Gaps = 4/96 (4%)
Query: 1164 APIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223
A +++ + + PP++L+ + D + +SW + P I GYRIT PT G + E
Sbjct: 15 ALLLSSIEAEVDPPSDLNFKII-DENTVHMSWAKPVDP-IVGYRITVDPTT--DGPTKEF 70
Query: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPI 1259
+ A + L P EY V++ + + +ESVP+
Sbjct: 71 TLSASTTETLLSELVPETEYVVTITSYDEVEESVPV 106
Score = 45.1 bits (105), Expect = 8e-04
Identities = 23/110 (20%), Positives = 53/110 (48%), Gaps = 1/110 (0%)
Query: 790 VYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSV 849
+ Q+ ++ L S + P + +V + + W+ +P+TGY+++ +P
Sbjct: 313 ISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT 372
Query: 850 EGSSTE-LNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898
GS L++ ++++ DL +Y I++ A++ S P+ I ++T
Sbjct: 373 AGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKT 422
Score = 45.1 bits (105), Expect = 8e-04
Identities = 25/99 (25%), Positives = 45/99 (45%)
Query: 1896 VIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGV 1955
++ ++ PSNL + + + ++W P + +TGY + + R+ P
Sbjct: 327 LVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQT 386
Query: 1956 TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDEL 1994
T ++ L TEY I V A+K SEP+ +KT +
Sbjct: 387 TTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPM 425
Score = 44.3 bits (103), Expect = 0.001
Identities = 36/131 (27%), Positives = 52/131 (39%), Gaps = 21/131 (16%)
Query: 1439 LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG 1498
LL+ D P DL ++ +SW P + YRIT T + P +EFT+
Sbjct: 16 LLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSA 74
Query: 1499 SKSTATISGLKPGVDYTITVYAV----------------TGRGDSPASSKPISINYRTEI 1542
S + +S L P +Y +T+ + TG P KP +TEI
Sbjct: 75 STTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKP----GKTEI 130
Query: 1543 DKPSQMQVTDV 1553
K S TD+
Sbjct: 131 QKCSVSAWTDL 141
Score = 42.7 bits (99), Expect = 0.004
Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 1/86 (1%)
Query: 1903 IDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITG 1962
+D PS+L F N++ +SW P I GY I + P + TE ++
Sbjct: 25 VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTL-SASTTETLLSE 83
Query: 1963 LEPGTEYTIYVIALKNNQKSEPLIGR 1988
L P TEY + + + ++S P+IG+
Sbjct: 84 LVPETEYVVTITSYDEVEESVPVIGQ 109
Score = 36.2 bits (82), Expect = 0.39
Identities = 22/103 (21%), Positives = 45/103 (43%), Gaps = 1/103 (0%)
Query: 1795 LKDTLTSRPAQGVVTTLE-NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANG 1853
L L + A +++++E V PP E T+ +SW + I G+++ P
Sbjct: 5 LPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTD 64
Query: 1854 QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV 1896
+ T+ ++ L P T+Y + + + ++ S PV+
Sbjct: 65 GPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVI 107
Score = 36.2 bits (82), Expect = 0.39
Identities = 33/168 (19%), Positives = 67/168 (39%), Gaps = 14/168 (8%)
Query: 1807 VVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPAN-GQTPIQRTIKPDV 1865
+V+ E V PP + + + ++W +TG++V P G ++ P
Sbjct: 327 LVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQT 386
Query: 1866 RSYTITGLQPGTDYKIYLYTLNDNARSSP-----------VVIDASTAIDAPSNLRFLAT 1914
+ ++ L T+Y+I + + S P V ++ S +D +++ FL
Sbjct: 387 TTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVD 446
Query: 1915 TPNSL-LVSWQPPRARITGYIIKYE-KPGSPPREVVPRPRPGVTEATI 1960
S+ + ++ RA + + +E P +V R TE T+
Sbjct: 447 GSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTL 494
Score = 35.0 bits (79), Expect = 0.87
Identities = 24/95 (25%), Positives = 38/95 (40%), Gaps = 1/95 (1%)
Query: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
V P DL F + + V + W P + GYR+ V P G + + T ++
Sbjct: 25 VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83
Query: 967 LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT 1001
L P Y + + ES P+ Q T + + T
Sbjct: 84 LVPETEYVVTITSYDEVEESVPVIGQLTIQTGSST 118
Score = 33.5 bits (75), Expect = 2.5
Identities = 18/79 (22%), Positives = 37/79 (46%), Gaps = 6/79 (7%)
Query: 738 VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDG 797
+SW D + G+R+ + + +G ++ L ++ T + +L+P +Y+V + E
Sbjct: 43 MSWAKPVDPIVGYRITVDPTTDGPTKEF-TLSASTTETLLSELVPETEYVVTITSYDEVE 101
Query: 798 EQ-----SLILSTSQTTAP 811
E L + T +T P
Sbjct: 102 ESVPVIGQLTIQTGSSTKP 120
Score = 32.7 bits (73), Expect = 4.3
Identities = 29/126 (23%), Positives = 56/126 (44%), Gaps = 8/126 (6%)
Query: 1425 VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1484
++S V E+ L+ + V + P +L + + + ++W+ V Y++
Sbjct: 312 IISQVCSGVDEQLGELVSGEEVV-EPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTP 370
Query: 1485 TGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDK 1544
S +V +T ++ L +Y I+V A+ G SS+PISI +T+
Sbjct: 371 MTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGM----TSSEPISIMEKTQ--- 423
Query: 1545 PSQMQV 1550
P ++QV
Sbjct: 424 PMKVQV 429
>gi|153946395 tenascin C precursor [Homo sapiens]
Length = 2201
Score = 360 bits (925), Expect = 7e-99
Identities = 325/1394 (23%), Positives = 584/1394 (41%), Gaps = 73/1394 (5%)
Query: 609 SGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTI 668
S P ++ +TE + + + W+ +++Y++ + P + G + +PG S I
Sbjct: 624 SPPKDLVVTEVTEETVN--LAWD--NEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTII 679
Query: 669 KGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESV 728
+ L+PGV Y ++ +I + S PV++ T P
Sbjct: 680 QELEPGVEYFIRVFAILE-------------NKKSIPVSARVATYLPAP------EGLKF 720
Query: 729 TEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL-DLPSTATSVNIPDLLPGRKYI 787
I +S V W + + + + DE + L TS L PG++Y
Sbjct: 721 KSIKETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYE 780
Query: 788 VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYS- 846
++++ I ++ + L TT DAP V V DT+ ++ W +P A I G + Y
Sbjct: 781 ISLH-IVKNNTRGPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGI 839
Query: 847 PSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDT 906
V G T ++L E N ++ +L+P +Y +++ + + S P + TTG
Sbjct: 840 KDVPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAK-ETFTTG------ 892
Query: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQ-RLPISRN--TFAE 963
+ +PR+L+ V TD +T+ W ++A+ YR+ P++ G+H + +P S+ T
Sbjct: 893 LDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRIKYAPIS-GGDHAEVDVPKSQQATTKTT 951
Query: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQ 1023
+TGL PG Y V AV +ES P T T+LD P +LQ ++++ + W P A+
Sbjct: 952 LTGLRPGTEYGIGVSAVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAK 1011
Query: 1024 ITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT 1083
YRL L GQ + + + Y LR L+P EY V L A KG +S A +
Sbjct: 1012 FDRYRLNYSLPT-GQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKAS 1070
Query: 1084 TLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSG--SIV 1139
T Q TEV + + WT A + F + V+ + EA R +T ++
Sbjct: 1071 TEQAPELENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVD 1130
Query: 1140 VSGLTPGVEYVYTIQVLRDGQERDAPIVN-KVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
+ GL Y +I + G P+++ + T +P + A L ++W
Sbjct: 1131 IPGLKAATPYTVSIYGVIQGYR--TPVLSAEASTGETPNLGEVVVAEVGWDALKLNW--- 1185
Query: 1199 TTPDITGYRITTTPTNGQQGNSLEEV----VHADQSSCTFDNLSPGLEYNVSVYTVKDDK 1254
T P+ Y Q+ +++E V S L Y +++ V D
Sbjct: 1186 TAPE-GAYEYFFIQV--QEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDF 1242
Query: 1255 ESVPIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE 1313
+ P+S + + VP +L T + D +R+ W P F ++ E+
Sbjct: 1243 STTPLSVEVLTEEVPDMGNLTVTEVSWDALRLNWTTPDGT-YDQFTIQVQEADQVEEAHN 1301
Query: 1314 LSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITAN 1372
L++ S ++ + L GT Y V++ H + PL T L + S++ +
Sbjct: 1302 LTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWD 1361
Query: 1373 SFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN 1432
++W A + I+ + + +P S ++ + L T Y VSI +
Sbjct: 1362 GLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVI 1421
Query: 1433 GREESPLLIGQQSTVSDVP-RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1491
+P+L + ST + +L V TP S +SW A + I ++
Sbjct: 1422 RGYRTPVLSAEASTAKEPEIGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLET 1481
Query: 1492 QEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA-SSKPISINYRTE-IDKPSQMQ 1549
E+ + G++ TA ISGL P D+ + + G +P+ +K IS TE + +
Sbjct: 1482 VEYNISGAERTAHISGLPPSTDFIVYL-----SGLAPSIRTKTISATATTEALPLLENLT 1536
Query: 1550 VTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYV 1609
++D+ +V W+ S + + VT + T Q ++ + GL + Y
Sbjct: 1537 ISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYE 1596
Query: 1610 VSVYAQNPSGESQPLVQTAVTNID-RPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSS 1668
V V +++PL VT + L +D D +++W + +G + +
Sbjct: 1597 VMVSGFTQGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRD 1656
Query: 1669 PEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDL 1728
+ L E T ++ GLR +EY + + + SQ + +TA+ +P ++
Sbjct: 1657 TKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRSQTVSAIATTAMGSPKEV 1716
Query: 1729 KFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKY 1788
F+ +T S + W P Q+ +R+ P P + + + + L+ +Y
Sbjct: 1717 IFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSM-VTVDGTKTQTRLVKLIPGVEY 1775
Query: 1789 EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDA 1848
VS+ A+K S P G TT + P + T++ W+ T+ + + +
Sbjct: 1776 LVSIIAMKGFEESEPVSGSFTTA--LDGPSGLVTANITDSEALARWQPAIATVDSYVI-S 1832
Query: 1849 VPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSN 1908
I RT+ + Y +T L+P T+Y + ++ +SS + +T +D+P +
Sbjct: 1833 YTGEKVPEITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTDLDSPRD 1892
Query: 1909 LRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTE 1968
L + L++W+PPRA +TGY++ YE +EV+ P T ++ L P T
Sbjct: 1893 LTATEVQSETALLTWRPPRASVTGYLLVYESVDGTVKEVI--VGPDTTSYSLADLSPSTH 1950
Query: 1969 YTIYVIALKNNQKS 1982
YT + AL +S
Sbjct: 1951 YTAKIQALNGPLRS 1964
Score = 342 bits (876), Expect = 3e-93
Identities = 309/1300 (23%), Positives = 527/1300 (40%), Gaps = 79/1300 (6%)
Query: 728 VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYI 787
VTE+T + ++W + V+ + V Y + EG +P TS I +L PG +Y
Sbjct: 631 VTEVTEETVNLAWDNEM-RVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEPGVEYF 689
Query: 788 VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVY-- 845
+ V+ I E+ ++S+ +S T AP + +TS+ V W + I++
Sbjct: 690 IRVFAILEN-KKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFETWEIIFRN 748
Query: 846 -SPSVEGSSTE-LNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPR 903
+ EG T+ L PET+ T L PG +Y I+++ V+ N + + T R
Sbjct: 749 MNKEDEGEITKSLRRPETSYRQT--GLAPGQEYEISLHIVKNNTRGPGL----KRVTTTR 802
Query: 904 SDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQ-RLPISRNTFA 962
D +P ++ +VTD I W P + + G + ++PG+ L N ++
Sbjct: 803 LD---APSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYS 859
Query: 963 EVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRA 1022
+ L P Y + + S P TT LDAP NL+ V++TD+++ + W +A
Sbjct: 860 -IGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKA 918
Query: 1023 QITGYRLTVGLTRRGQPRQYNVGPS---VSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079
I YR+ G + +V S +K L L+P +EY + + A+K ++ES AT
Sbjct: 919 AIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNPAT 978
Query: 1080 -GVFTTLQPGSSIPPYNTEVTETTIVITW-TPAP-----RIGFKLGVRPSQGGEAPREVT 1132
T L + +E ET++ + W TP R+ + L G + PR T
Sbjct: 979 INAATELDTPKDLQV--SETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLPRNTT 1036
Query: 1133 SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLT 1192
S V+ GL PG EY + G+ + P K T +P + V
Sbjct: 1037 S----YVLRGLEPGQEY-NVLLTAEKGRHKSKPARVKASTEQAPELE-------NLTVTE 1084
Query: 1193 VSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPG------------ 1240
V W+ G R+ T + + + +V A++ + PG
Sbjct: 1085 VGWD--------GLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKA 1136
Query: 1241 -LEYNVSVY-TVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNF 1298
Y VS+Y ++ + V ++ P ++ +G D +++ W P F
Sbjct: 1137 ATPYTVSIYGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGA-YEYF 1195
Query: 1299 LVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL 1358
++ E L++ + L L T Y +++ V + +TPL T
Sbjct: 1196 FIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEE 1255
Query: 1359 DSPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
G + ++++ ++ ++W P T + I+ VP S S+ +
Sbjct: 1256 VPDMGNLTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPG 1315
Query: 1418 LTPGTEYVVSIVA-LNGREESPLLIGQQSTVSDVPR--DLEVVAATPTSLLISWDAPAVT 1474
L GT Y V++ + G PL + + D+P+ DL V L ++W A
Sbjct: 1316 LRAGTPYTVTLHGEVRGHSTRPLAV--EVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNA 1373
Query: 1475 VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPI 1534
++ I E Q T+PGS I GL+ Y +++Y V +P S
Sbjct: 1374 YEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEA 1433
Query: 1535 SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594
S EI + V+D+ S ++ W+ + + + N T +
Sbjct: 1434 STAKEPEI---GNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAE 1490
Query: 1595 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTDVDVDSIKIAWE 1653
I GL P+ +++V + PS ++ + TA T + + L +D++ ++W
Sbjct: 1491 RTAHISGLPPSTDFIVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWM 1550
Query: 1654 SPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQP 1713
+ + + VT + G + EL+GL G Y V V +++P
Sbjct: 1551 ASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKP 1610
Query: 1714 LIGTQST-AIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAP 1772
L T A P +L + TP WT + +++ +K EI L
Sbjct: 1611 LRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLA 1670
Query: 1773 DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITI 1832
+ ++GL AT+YE+ +Y + S+ + TT + P+ +D TE + T+
Sbjct: 1671 PERTRDITGLREATEYEIELYGISKGRRSQTVSAIATTA--MGSPKEVIFSDITENSATV 1728
Query: 1833 SWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARS 1892
SWR T + F++ VP G TP T+ + L PG +Y + + + S
Sbjct: 1729 SWRAPTAQVESFRITYVPITGGTPSMVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEES 1788
Query: 1893 SPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPR 1952
PV +TA+D PS L T + L WQP A + Y+I Y G E+
Sbjct: 1789 EPVSGSFTTALDGPSGLVTANITDSEALARWQPAIATVDSYVISY--TGEKVPEITRTVS 1846
Query: 1953 PGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTD 1992
E +T LEP TEYT+ + A K QKS + + TD
Sbjct: 1847 GNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTD 1886
Score = 313 bits (803), Expect = 1e-84
Identities = 308/1264 (24%), Positives = 532/1264 (42%), Gaps = 96/1264 (7%)
Query: 665 SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVAT 724
SY GL PG YE L ++ +T P T S +
Sbjct: 767 SYRQTGLAPGQEYEISLHIVKN--------------NTRGPGLKRVTTTRLDAPSQI--- 809
Query: 725 SESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGR 784
V ++T ++ +++W + G + Y + + + +DL +I +L P
Sbjct: 810 --EVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYSIGNLKPDT 867
Query: 785 KYIVNVYQISEDGEQSLILSTSQ-TTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRI 843
+Y V++ IS G+ S + TT DAP + D SI + W +A I YRI
Sbjct: 868 EYEVSL--ISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRI 925
Query: 844 VYSPSVEGSSTELNLPETANSVT---LSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
Y+P G E+++P++ + T L+ L+PG +Y I + AV+E++ES P I T
Sbjct: 926 KYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNPATINAATE- 984
Query: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
+ +P+DLQ E + +T++W P + YR++ +LP + + RNT
Sbjct: 985 ------LDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNY---SLPTGQWVGVQLPRNT 1035
Query: 961 FAEVT-GLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT--NLQFVNETDSTVLVRW 1017
+ V GL PG Y + A +SKP + +T+ AP NL + + W
Sbjct: 1036 TSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTE-QAPELENLTVTEVGWDGLRLNW 1094
Query: 1018 TPPRAQITGYRLTVGLTRRGQP-RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
T + + V + + R V S+ + L+ A+ YTVS+ + +P
Sbjct: 1095 TAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQGYRTP 1154
Query: 1077 KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFK---LGVRPSQGGEAPREVTS 1133
+ +T + + EV + + WT AP ++ + V+ + EA + +T
Sbjct: 1155 VLSAEASTGETPNLGEVVVAEVGWDALKLNWT-APEGAYEYFFIQVQEADTVEAAQNLTV 1213
Query: 1134 DSG--SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVL 1191
G S + GL Y TI+ G +D TPLS + E PD G L
Sbjct: 1214 PGGLRSTDLPGLKAATHYTITIR----GVTQDFS-----TTPLS--VEVLTEEVPDMGNL 1262
Query: 1192 TV---SWERS----TTPDITGYRITTTPTNGQQGNSLEEV----VHADQSSCTFDNLSPG 1240
TV SW+ TTPD T + T Q+ + +EE V S L G
Sbjct: 1263 TVTEVSWDALRLNWTTPDGTYDQFTIQV---QEADQVEEAHNLTVPGSLRSMEIPGLRAG 1319
Query: 1241 LEYNVSVYTVKDDKESVPIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFL 1299
Y V+++ + P++ + + +P DL + +G D +R+ W + +F+
Sbjct: 1320 TPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNA-YEHFV 1378
Query: 1300 VRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1359
++ V E L++ S AV + L T Y VS+ V + + L T +
Sbjct: 1379 IQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKE 1438
Query: 1360 SPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNL 1418
G ++ SDIT SF + W+A + I + E + + + ++ L
Sbjct: 1439 PEIGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGL 1498
Query: 1419 TPGTEYVVSIVALNGREESPLLIGQQSTVSDVP--RDLEVVAATPTSLLISWDAPAVTVR 1476
P T+++V + L + I +T +P +L + P +SW A
Sbjct: 1499 PPSTDFIVYLSGLAPSIRTKT-ISATATTEALPLLENLTISDINPYGFTVSWMASENAFD 1557
Query: 1477 YYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISI 1536
+ +T ++G QEFT+ G++ + GL G+ Y + V T +KP+
Sbjct: 1558 SFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFT----QGHQTKPLRA 1613
Query: 1537 NYRTEID-KPSQMQVTDVQDNSISVKWLPSSSPVTGY--RVTTTPKNGPGPTKTKTAGPD 1593
TE + + + V+D + + W + ++ T K P + P+
Sbjct: 1614 EIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSE-PLEITLLAPE 1672
Query: 1594 QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWE 1653
+T I GL+ EY + +Y + SQ + A T + PK + F+D+ +S ++W
Sbjct: 1673 RTR-DITGLREATEYEIELYGISKGRRSQTVSAIATTAMGSPKEVIFSDITENSATVSWR 1731
Query: 1654 SPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQP 1713
+P QV +R+TY G + DG + L L PG EY VS++A+ ES+P
Sbjct: 1732 APTAQVESFRITYVPITGGTPSMVTV-DGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEP 1790
Query: 1714 LIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD 1773
+ G+ +TA+ P+ L +T + A+W P + Y + T ++ + EI
Sbjct: 1791 VSGSFTTALDGPSGLVTANITDSEALARWQPAIATVDSYVISYTGEK----VPEITRTVS 1846
Query: 1774 SSSV--VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTIT 1831
++V ++ L AT+Y + ++A K S TT ++ PR T+ T
Sbjct: 1847 GNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTT--DLDSPRDLTATEVQSETAL 1904
Query: 1832 ISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNAR 1891
++WR ++TG+ + +G T + + PD SY++ L P T Y + LN R
Sbjct: 1905 LTWRPPRASVTGYLLVYESVDG-TVKEVIVGPDTTSYSLADLSPSTHYTAKIQALNGPLR 1963
Query: 1892 SSPV 1895
S+ +
Sbjct: 1964 SNMI 1967
Score = 277 bits (708), Expect = 1e-73
Identities = 270/1107 (24%), Positives = 446/1107 (40%), Gaps = 59/1107 (5%)
Query: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
V P+DL EVT+ V + W E VT Y V P + G Q T +
Sbjct: 623 VSPPKDLVVTEVTEETVNLAW-DNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQE 681
Query: 967 LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITG 1026
L PGV Y+ +VFA+ ++S P++A+ T L AP L+F + +++V V W P
Sbjct: 682 LEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFET 741
Query: 1027 YRL---TVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT 1083
+ + + G+ + P S Y L P EY +SL +K N P V T
Sbjct: 742 WEIIFRNMNKEDEGEITKSLRRPETS-YRQTGLAPGQEYEISLHIVKNNTRGPGLKRVTT 800
Query: 1084 T-LQPGSSIPPYNTEVTETTIVITW-TPAPRI-GFKL--GVRPSQGGEAPREVTSDSGSI 1138
T L S I +VT+TT +ITW P I G +L G++ G ++T D
Sbjct: 801 TRLDAPSQIEV--KDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQY 858
Query: 1139 VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
+ L P EY ++ + R G P T L P NL + D + T+ W R+
Sbjct: 859 SIGNLKPDTEYEVSL-ISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSI-TLEW-RN 915
Query: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQ---SSCTFDNLSPGLEYNVSVYTVKDDKE 1255
I YRI P +G G+ E V Q + T L PG EY + V VK+DKE
Sbjct: 916 GKAAIDSYRIKYAPISG--GDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKE 973
Query: 1256 SVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELS 1315
S P + + P DL+ + ++ + W P + + + YS + +
Sbjct: 974 SNPATINAATELDTPKDLQVSETAETSLTLLWKTPLA-KFDRYRLNYSLPTGQ--WVGVQ 1030
Query: 1316 ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANSF 1374
+ + + VL L PG EY V +++ +H+S P R + T + +++ +
Sbjct: 1031 LPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEVGWDGL 1090
Query: 1375 TVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR 1434
++W A + I+ + R VP S ++ + L T Y VSI +
Sbjct: 1091 RLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQG 1150
Query: 1435 EESPLLIGQQSTVSDVPRDLEVVAATP--TSLLISWDAPAVTVRYYRITYGETGGNSPVQ 1492
+P+L + ST + P EVV A +L ++W AP Y+ I E Q
Sbjct: 1151 YRTPVLSAEAST-GETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVEAAQ 1209
Query: 1493 EFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRT-EIDKPSQMQVT 1551
TVPG + + GLK YTIT+ VT S+ P+S+ T E+ + VT
Sbjct: 1210 NLTVPGGLRSTDLPGLKAATHYTITIRGVT----QDFSTTPLSVEVLTEEVPDMGNLTVT 1265
Query: 1552 DVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVS 1611
+V +++ + W + + + T M I GL+ Y V+
Sbjct: 1266 EVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVT 1325
Query: 1612 VYAQNPSGESQPLVQTAVTNIDRPK--GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSP 1669
++ + ++PL VT D P+ LA ++V D +++ W + + +
Sbjct: 1326 LHGEVRGHSTRPLAVEVVTE-DLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEV 1384
Query: 1670 EDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA-IPAPTDL 1728
G ++ GL + Y VS+ + + L STA P +L
Sbjct: 1385 NKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKEPEIGNL 1444
Query: 1729 KFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKY 1788
+ +TP S + W + + + + + E N++ + +SGL +T +
Sbjct: 1445 NVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDF 1504
Query: 1789 EVSVYALKDTLTSRPAQGVVTT-----LENVSPPRRARVTDATETTITISWRTKTETITG 1843
V + L ++ ++ TT LEN++ ++D T+SW
Sbjct: 1505 IVYLSGLAPSIRTKTISATATTEALPLLENLT------ISDINPYGFTVSWMASENAFDS 1558
Query: 1844 FQVDAVPANG-QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP----VVID 1898
F V V + P + T+ R + GL G Y++ + ++ P +V +
Sbjct: 1559 FLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTE 1618
Query: 1899 ASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYE--KPGSPPREVVPRPRPGVT 1956
A +D NL TP+ +SW +++K K S P E+
Sbjct: 1619 AEPEVD---NLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTR 1675
Query: 1957 EATITGLEPGTEYTIYVIALKNNQKSE 1983
+ ITGL TEY I + + ++S+
Sbjct: 1676 D--ITGLREATEYEIELYGISKGRRSQ 1700
Score = 270 bits (689), Expect = 2e-71
Identities = 277/1182 (23%), Positives = 475/1182 (40%), Gaps = 87/1182 (7%)
Query: 664 NSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVA 723
N Y+I LKP YE LIS R D + S P TG P + L
Sbjct: 856 NQYSIGNLKPDTEYEVSLIS---------RRGDMS----SNPAKETFTTGLDAPRN-LRR 901
Query: 724 TSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPST---ATSVNIPDL 780
S+ T +S + W + + +R++Y GD + +D+P + T + L
Sbjct: 902 VSQ-----TDNSITLEWRNGKAAIDSYRIKYAPISGGDHAE-VDVPKSQQATTKTTLTGL 955
Query: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
PG +Y + V + ED E + + + T D P D V + +TS+ + W P A
Sbjct: 956 RPGTEYGIGVSAVKEDKESNPA-TINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDR 1014
Query: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
YR+ YS G + LP S L L+PG +YN+ + A + +S P ++ T
Sbjct: 1015 YRLNYSLPT-GQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKAST-- 1071
Query: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
+ P +L EV + + WT + A + + V N E + L + +
Sbjct: 1072 ----EQAPELENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKV-EAARNLTVPGSL 1126
Query: 961 FA-EVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVL-VRWT 1018
A ++ GL Y ++ V G + L+A+ +T V E L + WT
Sbjct: 1127 RAVDIPGLKAATPYTVSIYGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWT 1186
Query: 1019 PPRAQITGYRLTVGLTRRGQPRQYNVGPS-VSKYPLRNLQPASEYTVSLVAIKGN-QESP 1076
P + + V + Q P + L L+ A+ YT+++ + + +P
Sbjct: 1187 APEGAYEYFFIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTP 1246
Query: 1077 KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSD 1134
+ V T P TEV+ + + WT F + V+ + E +T
Sbjct: 1247 LSVEVLTEEVPDMGNLTV-TEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVP 1305
Query: 1135 SG--SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLT 1192
S+ + GL G Y T+ G P+ +VVT P D V
Sbjct: 1306 GSLRSMEIPGLRAGTPYTVTLHGEVRGHST-RPLAVEVVTEDLPQLG-------DLAVSE 1357
Query: 1193 VSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLS----------PGLE 1242
V W+ G R+ T + + + +V ++ NL+ PGLE
Sbjct: 1358 VGWD--------GLRLNWTAADNAYEHFVIQVQEVNKVEAA-QNLTLPGSLRAVDIPGLE 1408
Query: 1243 ----YNVSVY-TVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTN 1297
Y VS+Y ++ + V ++ P +L ++I P++ ++W I T
Sbjct: 1409 AATPYRVSIYGVIRGYRTPVLSAEASTAKEPEIGNLNVSDITPESFNLSWMATDGIFET- 1467
Query: 1298 FLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT- 1356
F + + E +IS ++ ++ L P T+++V +S + + + T
Sbjct: 1468 FTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATATTE 1527
Query: 1357 GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT 1416
L + SDI FTV W+A + + P+E + ++ + L
Sbjct: 1528 ALPLLENLTISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELR 1587
Query: 1417 NLTPGTEYVVSIVALN-GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTV 1475
L G Y V + G + PL + +L V ATP +SW A
Sbjct: 1588 GLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVF 1647
Query: 1476 RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT-GRGDSPASSKPI 1534
+ + +T S E T+ + T I+GL+ +Y I +Y ++ GR S+ +
Sbjct: 1648 DNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGR-----RSQTV 1702
Query: 1535 SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594
S T + P ++ +D+ +NS +V W ++ V +R+T P G P+ G +
Sbjct: 1703 SAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDGT-K 1761
Query: 1595 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWES 1654
T+ + L P VEY+VS+ A ES+P+ + T +D P GL ++ W+
Sbjct: 1762 TQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALDGPSGLVTANITDSEALARWQP 1821
Query: 1655 PQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPL 1714
V Y ++Y+ + + E+ G L L P +EYT+ + A +S +
Sbjct: 1822 AIATVDSYVISYTGEK--VPEITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTI 1879
Query: 1715 IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS 1774
+T + +P DL T+V + W PP +TGY + + G +KE+ + PD+
Sbjct: 1880 TAKFTTDLDSPRDLTATEVQSETALLTWRPPRASVTGYLL--VYESVDGTVKEVIVGPDT 1937
Query: 1775 SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSP 1816
+S ++ L +T Y + AL L S Q + TT+ + P
Sbjct: 1938 TSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTTIGLLYP 1979
Score = 256 bits (654), Expect = 2e-67
Identities = 251/1095 (22%), Positives = 446/1095 (40%), Gaps = 51/1095 (4%)
Query: 1096 TEVTETTIVITWTPAPRIGFKLGV-RPSQGG--EAPREVTSDSGSIVVSGLTPGVEYVYT 1152
TEVTE T+ + W R+ L V P+ G E V D S ++ L PGVEY
Sbjct: 632 TEVTEETVNLAWDNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEPGVEYFIR 691
Query: 1153 IQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTP 1212
+ + + + + P+ +V T L P L ++ +T V V W+ T + I
Sbjct: 692 VFAILENK-KSIPVSARVATYLPAPEGLKFKSIKETSV-EVEWDPLDIAFET-WEIIFRN 748
Query: 1213 TNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTD 1272
N + + + + ++S L+PG EY +S++ VK++ + + P+
Sbjct: 749 MNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGLKRVTTTRLDAPSQ 808
Query: 1273 LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332
+ ++ T +TW P + ++ + Y D + ++ +N + NL P T
Sbjct: 809 IEVKDVTDTTALITWFKPLA-EIDGIELTYGIKDVPGDRTTIDLTEDENQYSIGNLKPDT 867
Query: 1333 EYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRH 1392
EY VS+ S S P + TGLD+P + T NS T+ W +A I YRI++
Sbjct: 868 EYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRIKY 927
Query: 1393 HPEHFSGRPREDRVPHSRNSITLTNLT---PGTEYVVSIVALNGREESPLLIGQQSTVSD 1449
P G E VP S+ + T T LT PGTEY + + A+ +ES +T D
Sbjct: 928 APIS-GGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNPATINAATELD 986
Query: 1450 VPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG-ETGGNSPVQEFTVPGSKSTATISGL 1508
P+DL+V TSL + W P YR+ Y TG VQ +P + ++ + GL
Sbjct: 987 TPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQ---LPRNTTSYVLRGL 1043
Query: 1509 KPGVDYTITVYAVTGRGDSPASSKPISINYRTE-IDKPSQMQVTDVQDNSISVKWLPSSS 1567
+PG +Y + + A GR SKP + TE + + VT+V + + + W +
Sbjct: 1044 EPGQEYNVLLTAEKGRH----KSKPARVKASTEQAPELENLTVTEVGWDGLRLNWTAADQ 1099
Query: 1568 PVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT 1627
+ + N + T + I GL+ Y VS+Y G P++
Sbjct: 1100 AYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVI-QGYRTPVLSA 1158
Query: 1628 AVTNIDRPK--GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPED-GIHELFPAPDGEE 1684
+ + P + +V D++K+ W +P+G + + + + P G
Sbjct: 1159 EASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVEAAQNLTVPGGLR 1218
Query: 1685 DTAELQGLRPGSEYTVSVVALHDDMESQPL-IGTQSTAIPAPTDLKFTQVTPTSLSAQWT 1743
T +L GL+ + YT+++ + D + PL + + +P +L T+V+ +L WT
Sbjct: 1219 ST-DLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMGNLTVTEVSWDALRLNWT 1277
Query: 1744 PPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP 1803
P+ + ++V ++ + + S+ + GL T Y V+++ ++RP
Sbjct: 1278 TPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRP 1337
Query: 1804 AQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQR-TIK 1862
V T E++ V++ + ++W F + N Q T+
Sbjct: 1338 LAVEVVT-EDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLP 1396
Query: 1863 PDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP-SNLRFLATTPNSLLV 1921
+R+ I GL+ T Y++ +Y + R+ + +ASTA + NL TP S +
Sbjct: 1397 GSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKEPEIGNLNVSDITPESFNL 1456
Query: 1922 SWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 1981
SW + I+ V A I+GL P T++ +Y+ L + +
Sbjct: 1457 SWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIR 1516
Query: 1982 SEPLIGRKKTDELPQL--VTLPHPNLHGPEILDVPS---------TVQKTPFVTHPGYDT 2030
++ + T+ LP L +T+ N +G + + S TV + + P T
Sbjct: 1517 TKTISATATTEALPLLENLTISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFT 1576
Query: 2031 GNGIQLP-GTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTT 2089
+G Q G +G +++ T P A + P V +S T
Sbjct: 1577 LSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEA----EPEVDNLLVSDAT 1632
Query: 2090 -----ISWAPFQDT-SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEA 2143
+SW + +++ EPL+ + + +TGL Y I +
Sbjct: 1633 PDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYG 1692
Query: 2144 LKDQQRHKVREEVVT 2158
+ +R + + T
Sbjct: 1693 ISKGRRSQTVSAIAT 1707
Score = 240 bits (612), Expect = 1e-62
Identities = 247/1064 (23%), Positives = 437/1064 (41%), Gaps = 90/1064 (8%)
Query: 1174 LSPPTNLHL-EANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSC 1232
+SPP +L + E +T + ++W+ +T Y + TPT+ + G ++ V DQ+S
Sbjct: 623 VSPPKDLVVTEVTEET--VNLAWDNEMR--VTEYLVVYTPTH-EGGLEMQFRVPGDQTST 677
Query: 1233 TFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPS 1292
L PG+EY + V+ + ++K+S+P+S + +P P L+F +I ++ V W P
Sbjct: 678 IIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDI 737
Query: 1293 IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRG 1352
T ++ + K +E S+ + + T L PG EY +S+ V L+
Sbjct: 738 AFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGLKR 797
Query: 1353 RQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNS 1412
T LD+P+ I+ D+T + + W P A I G + + + G + N
Sbjct: 798 VTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQ 857
Query: 1413 ITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA 1472
++ NL P TEY VS+++ G S +T D PR+L V+ T S+ + W
Sbjct: 858 YSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGK 917
Query: 1473 VTVRYYRITYGETGGNSPVQEFTVPGSK---STATISGLKPGVDYTITVYAVTGRGDSPA 1529
+ YRI Y G E VP S+ + T++GL+PG +Y I V AV
Sbjct: 918 AAIDSYRIKYAPISGGDHA-EVDVPKSQQATTKTTLTGLRPGTEYGIGVSAV----KEDK 972
Query: 1530 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPG-----P 1584
S P +IN TE+D P +QV++ + S+++ W + YR+ + G P
Sbjct: 973 ESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLP 1032
Query: 1585 TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTNIDRPKGLAFTDV 1643
T T + GL+P EY V + A+ +S+P V+ + + L T+V
Sbjct: 1033 RNT-------TSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEV 1085
Query: 1644 DVDSIKIAWESPQGQVSRY--RVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVS 1701
D +++ W + + +V ++ + L G ++ GL+ + YTVS
Sbjct: 1086 GWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNL--TVPGSLRAVDIPGLKAATPYTVS 1143
Query: 1702 VVALHDDMESQPLIGTQSTA-IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKE 1760
+ + + L ST P ++ +V +L WT P + ++V +
Sbjct: 1144 IYGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEAD 1203
Query: 1761 KTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRA 1820
+ + + S + GL AT Y +++ + ++ P V T E V
Sbjct: 1204 TVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLT-EEVPDMGNL 1262
Query: 1821 RVTDATETTITISWRTKTETITGFQVDAVPANG-QTPIQRTIKPDVRSYTITGLQPGTDY 1879
VT+ + + ++W T T F + A+ + T+ +RS I GL+ GT Y
Sbjct: 1263 TVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPY 1322
Query: 1880 KIYLYTLNDNARSSPVVIDASTAIDAP--SNLRFLATTPNSLLVSWQPPRARITGYIIKY 1937
+ L+ + P+ ++ T D P +L + L ++W ++I+
Sbjct: 1323 TVTLHGEVRGHSTRPLAVEVVTE-DLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQV 1381
Query: 1938 EKPGSPPREVVPRPRPGVTEAT-ITGLEPGTEY--TIY---------VIALKNNQKSEPL 1985
++ + PG A I GLE T Y +IY V++ + + EP
Sbjct: 1382 QEV-NKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKEPE 1440
Query: 1986 IGRKKTDEL-PQLVTLPHPNLHG------PEILDVPSTVQKTPFVTHPGYDTGNGIQLPG 2038
IG ++ P+ L G EI+D ++ + T + LP
Sbjct: 1441 IGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPP 1500
Query: 2039 T-------SGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTIS 2091
+ SG PS+ + I T T A P+ + T+S
Sbjct: 1501 STDFIVYLSGLAPSIRTKTI-------SATATTEALPLLEN-----LTISDINPYGFTVS 1548
Query: 2092 WAPFQDT-SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEAL-KDQQR 2149
W ++ ++++ G +P +F + GT L GL G Y ++V + Q
Sbjct: 1549 WMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQT 1608
Query: 2150 HKVREEVVT----------VGNSVNEG--LNQPTDDSCFDPYTV 2181
+R E+VT V ++ +G L+ D+ FD + +
Sbjct: 1609 KPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVL 1652
Score = 217 bits (552), Expect = 1e-55
Identities = 186/819 (22%), Positives = 340/819 (41%), Gaps = 47/819 (5%)
Query: 1352 GRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRN 1411
G + + P + +++T + + W +T Y + + P H G + RVP +
Sbjct: 617 GEDCSEVSPPKDLVVTEVTEETVNLAW-DNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQT 675
Query: 1412 SITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP 1471
S + L PG EY + + A+ ++S + + +T P L+ + TS+ + WD
Sbjct: 676 STIIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPL 735
Query: 1472 AVTVRYYRITYGETGGNSPVQ-EFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS 1530
+ + I + + ++ +++ +GL PG +Y I+++ V P
Sbjct: 736 DIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGL 795
Query: 1531 SKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTA 1590
+ + T +D PSQ++V DV D + + W + + G +T K+ PG T
Sbjct: 796 KRVTT----TRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDL 851
Query: 1591 GPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKI 1650
D+ + +I L+P EY VS+ ++ S P +T T +D P+ L +SI +
Sbjct: 852 TEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITL 911
Query: 1651 AWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE--LQGLRPGSEYTVSVVALHDD 1708
W + + + YR+ Y+ G H P ++ T + L GLRPG+EY + V A+ +D
Sbjct: 912 EWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKED 971
Query: 1709 MESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEI 1768
ES P +T + P DL+ ++ TSL+ W P + YR+ + TG +
Sbjct: 972 KESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYS--LPTGQWVGV 1029
Query: 1769 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATET 1828
L +++S V+ GL +Y V + A K S+PA+ V + E VT+
Sbjct: 1030 QLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPAR-VKASTEQAPELENLTVTEVGWD 1088
Query: 1829 TITISWRTKTETITGFQVDAVPANG-QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1887
+ ++W + F + AN + T+ +R+ I GL+ T Y + +Y +
Sbjct: 1089 GLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVI 1148
Query: 1888 DNARSSPVVIDASTAIDAPSNLRFLATTP---NSLLVSWQPPRARITGYIIKYEKPGSPP 1944
R+ + +AST + P NL + ++L ++W P + I+ ++ +
Sbjct: 1149 QGYRTPVLSAEASTG-ETP-NLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVE 1206
Query: 1945 REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPN 2004
G+ + GL+ T YTI + + + + PL T+E+P + L
Sbjct: 1207 AAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMGNL---- 1262
Query: 2005 LHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPS-----VGQQMIFEEHGFRR 2059
+ +V + + T G IQ+ + + G E G R
Sbjct: 1263 ----TVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRA 1318
Query: 2060 TTPPTTAT--PIR-HRPRPYP--------PNVGQEALSQT-----TISWAPFQDTSE-YI 2102
TP T +R H RP P +G A+S+ ++W + E ++
Sbjct: 1319 GTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFV 1378
Query: 2103 ISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIV 2141
I V E +PG+ + + GL Y + +
Sbjct: 1379 IQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSI 1417
Score = 187 bits (475), Expect = 1e-46
Identities = 155/570 (27%), Positives = 255/570 (44%), Gaps = 54/570 (9%)
Query: 1630 TNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAEL 1689
+ + PK L T+V +++ +AW++ +V+ Y V Y+ +G E+ G++ + +
Sbjct: 621 SEVSPPKDLVVTEVTEETVNLAWDNEM-RVTEYLVVYTPTHEGGLEMQFRVPGDQTSTII 679
Query: 1690 QGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQL 1749
Q L PG EY + V A+ ++ +S P+ +T +PAP LKF + TS+ +W P ++
Sbjct: 680 QELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAF 739
Query: 1750 TGYRV--RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV 1807
+ + R KE G + + P++S +GL +YE+S++ +K+ + V
Sbjct: 740 ETWEIIFRNMNKEDEGEITKSLRRPETS-YRQTGLAPGQEYEISLHIVKNNTRGPGLKRV 798
Query: 1808 VTTLENVSPPRRARVTDATETTITISWRTKTETITGFQ----VDAVPANGQTPIQRTIKP 1863
TT + P + V D T+TT I+W I G + + VP + +T I T
Sbjct: 799 TTT--RLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGD-RTTIDLT--E 853
Query: 1864 DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSW 1923
D Y+I L+P T+Y++ L + + S+P +T +DAP NLR ++ T NS+ + W
Sbjct: 854 DENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEW 913
Query: 1924 QPPRARITGYIIKYEK-PGSPPREV-VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 1981
+ +A I Y IKY G EV VP+ + T+ T+TGL PGTEY I V A+K +++
Sbjct: 914 RNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKE 973
Query: 1982 SEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQ-------KTPFVTHPGY------ 2028
S P T+ L P+ L V T + KTP Y
Sbjct: 974 SNPATINAATE------------LDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSL 1021
Query: 2029 DTGN--GIQLPGTS------GQQPSVGQQ---MIFEEHGFRRTTPPTTATPIRHRPRPYP 2077
TG G+QLP + G +P GQ+ ++ E G ++ P P
Sbjct: 1022 PTGQWVGVQLPRNTTSYVLRGLEP--GQEYNVLLTAEKGRHKSKPARVKASTEQAPELEN 1079
Query: 2078 PNVGQEALSQTTISW-APFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGAT 2136
V + ++W A Q +II E VPG+ + + GL
Sbjct: 1080 LTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATP 1139
Query: 2137 YNIIVEALKDQQRHKVREEVVTVGNSVNEG 2166
Y + + + R V + G + N G
Sbjct: 1140 YTVSIYGVIQGYRTPVLSAEASTGETPNLG 1169
Score = 153 bits (386), Expect = 2e-36
Identities = 147/662 (22%), Positives = 264/662 (39%), Gaps = 40/662 (6%)
Query: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
+ W A ++ ++++ + N V + T+PG L + I GL+ Y + + +
Sbjct: 1365 LNWTAADNAY-EHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIR- 1422
Query: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
G++ TPV S + P + +V++IT SF +SW++
Sbjct: 1423 GYR-------------TPVLSAEASTAKEP----EIGNLNVSDITPESFNLSWMATDGIF 1465
Query: 748 SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQ 807
F +E S E ++ + +I L P +IV + ++ I +T+
Sbjct: 1466 ETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATAT 1525
Query: 808 TTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEG-SSTELNLPETANSVT 866
T A + T+ ++ V W + + + S + E L T +
Sbjct: 1526 TEALPLLENLTISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLE 1585
Query: 867 LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
L L G+ Y + + + ++ P+ + T P D +L + T +
Sbjct: 1586 LRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPEVD------NLLVSDATPDGFRLS 1639
Query: 927 WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
WT E + + + E + ++ ++TGL Y +++ +S GR S
Sbjct: 1640 WTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRS 1699
Query: 987 KPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGP 1046
+ ++A TT + +P + F + T+++ V W P AQ+ +R+T G P V
Sbjct: 1700 QTVSAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDG 1759
Query: 1047 SVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVIT 1106
+ ++ L L P EY VS++A+KG +ES +G FTT G S +T++ +
Sbjct: 1760 TKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALDGPS-GLVTANITDSEALAR 1818
Query: 1107 WTPAPRI--GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164
W PA + + + E R V+ ++ ++ L P EY I G ++ +
Sbjct: 1819 WQPAIATVDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPATEYTLRI-FAEKGPQKSS 1877
Query: 1165 PIVNKVVTPLSPPTNL-HLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223
I K T L P +L E +T +LT W R +TGY + + G E
Sbjct: 1878 TITAKFTTDLDSPRDLTATEVQSETALLT--W-RPPRASVTGYLLVYESVD---GTVKEV 1931
Query: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKES---VPISDTIIPAVPPPTDLRFTNIGP 1280
+V D +S + +LSP Y + + S I TI P P D +
Sbjct: 1932 IVGPDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTTIGLLYPFPKDCSQAMLNG 1991
Query: 1281 DT 1282
DT
Sbjct: 1992 DT 1993
>gi|157384973 tenascin R [Homo sapiens]
Length = 1358
Score = 353 bits (906), Expect = 1e-96
Identities = 262/867 (30%), Positives = 409/867 (47%), Gaps = 52/867 (5%)
Query: 783 GRKYIVNVYQISEDGEQSLILSTSQTTAPD----APP-DPTVDQVDDTSIVVRWSRPQAP 837
G++ +N E+ L + PD APP D V + D SI + W P A
Sbjct: 293 GQRQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPPEDLRVAGISDRSIELEWDGPMA- 351
Query: 838 ITGYRIVYSPSVEGS-STELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQ 896
+T Y I Y P+ G + +P + VT+++L+PG+ YNI++YAV N S P+ +
Sbjct: 352 VTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTYNISVYAVISNILSLPITAKV 411
Query: 897 ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPI 956
T + +P+ LQF +T+ V + W P + G+ + IP N G ++P
Sbjct: 412 AT-------HLSTPQGLQFKTITETTVEVQWEPFSFSFDGWEISFIPKNNEGGVIAQVPS 464
Query: 957 SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVR 1016
+F + TGL PG Y V A+ S P +A +T +D PT + + +D+ V
Sbjct: 465 DVTSFNQ-TGLKPGEEYIVNVVALKEQARSPPTSASVSTVIDGPTQILVRDVSDTVAFVE 523
Query: 1017 WTPPRAQITGYRLTVGLT-RRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQES 1075
W PPRA++ L GL G + + P +S+Y ++ L+P S Y VS+ A++G ES
Sbjct: 524 WIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRGTNES 583
Query: 1076 PKATGVFTTLQPGSSIPPYNTEV---TETTIVITW--TPAPRIGFKLGVRPSQGGEAPRE 1130
AT FTT P N V T T++ + W + A +K+ V + GE E
Sbjct: 584 DSATTQFTT----EIDAPKNLRVGSRTATSLDLEWDNSEAEVQEYKV-VYSTLAGEQYHE 638
Query: 1131 VTSDSG-----SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEAN 1185
V G ++ L PG EY I + + Q+ P T L P +L + A+
Sbjct: 639 VLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQ-SVPATMNARTELDSPRDLMVTAS 697
Query: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
+T + ++ W +++ P I YRIT TP++ G + E V D++S T +L PG EY +
Sbjct: 698 SETSI-SLIWTKASGP-IDHYRITFTPSS---GIASEVTVPKDRTSYTLTDLEPGAEYII 752
Query: 1246 SVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPV 1305
SV + ++S+ + P + L F+++ ++ +TW+ PS ++ YSP
Sbjct: 753 SVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWS-DPSPPADRLILNYSPR 811
Query: 1306 KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGID 1365
EE++ E+S+ + VL L P TEY+V++ +V+ S P+ G TG+D P I
Sbjct: 812 DEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITTGIDPPKDIT 871
Query: 1366 FSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYV 1425
S++T +S V W P A+ YR+ + P GR VP++ T+T L P TEY
Sbjct: 872 ISNVTKDSVMVSWSPPVASFDYYRVSYRPTQV-GRLDSSVVPNTVTEFTITRLNPATEYE 930
Query: 1426 VSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRI--TYG 1483
+S+ ++ GREES + T D P DL TPT L+ W AP V Y I T+
Sbjct: 931 ISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEALLQWKAPVGEVENYVIVLTHF 990
Query: 1484 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
G + V G + L P YT T+YA G P +S IS N+ T +D
Sbjct: 991 AVAG----ETILVDGVSEEFRLVDLLPSTHYTATMYATNG----PLTSGTISTNFSTLLD 1042
Query: 1544 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
P+ + ++V S + W P + + Y T K+ G K + T + +EGL
Sbjct: 1043 PPANLTASEVTRQSALISWQPPRAEIENY--VLTYKSTDGSRKELIVDAEDTWIRLEGLL 1100
Query: 1604 PTVEYVVSVYAQNPSGESQPLVQTAVT 1630
+Y V + A + S + TA T
Sbjct: 1101 ENTDYTVLLQAAQDTTWSS-ITSTAFT 1126
Score = 335 bits (860), Expect = 2e-91
Identities = 238/812 (29%), Positives = 379/812 (46%), Gaps = 30/812 (3%)
Query: 1174 LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
++PP +L + D + + W+ +T Y I+ PT G L++ V D S T
Sbjct: 326 VAPPEDLRVAGISDRSI-ELEWDGPMA--VTEYVISYQPT-ALGGLQLQQRVPGDWSGVT 381
Query: 1234 FDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSI 1293
L PGL YN+SVY V + S+PI+ + + P L+F I T+ V W P S
Sbjct: 382 ITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPF-SF 440
Query: 1294 DLTNFLVRYSPVKNEEDVAELSISPSD-NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRG 1352
+ + + P NE V ++ PSD + T L PG EY+V+V ++ EQ S P
Sbjct: 441 SFDGWEISFIPKNNEGGV--IAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSA 498
Query: 1353 RQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNS 1412
T +D PT I D++ V WI PRA + +++ G R+ +
Sbjct: 499 SVSTVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQ 558
Query: 1413 ITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA 1472
++ L PG+ Y VS+ A+ G ES Q +T D P++L V + T TSL + WD
Sbjct: 559 YSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDLEWDNSE 618
Query: 1473 VTVRYYRITYGETGGNSPVQEFTVP---GSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1529
V+ Y++ Y G E VP G + AT++ L PG +Y + + AV +
Sbjct: 619 AEVQEYKVVYSTLAGEQ-YHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVM----NSQ 673
Query: 1530 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1589
S P ++N RTE+D P + VT + SIS+ W +S P+ YR+T TP +G T
Sbjct: 674 QSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPSSGIA--SEVT 731
Query: 1590 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIK 1649
D+T T+ L+P EY++SV A+ +S A T L F+ V S+
Sbjct: 732 VPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVN 791
Query: 1650 IAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDM 1709
I W P R + YS ++ + + D + A L GL+P +EY V++VA+H +
Sbjct: 792 ITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTV 851
Query: 1710 ESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEIN 1769
S+P++G+ +T I P D+ + VT S+ W+PP YRV P + G +
Sbjct: 852 TSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQ-VGRLDSSV 910
Query: 1770 LAPDSSSVVVSGLMVATKYEVSVYALKDTLTS-RPAQGVVTTLENVSPPRRARVTDATET 1828
+ + ++ L AT+YE+S+ +++ S R V T ++N P T+ T T
Sbjct: 911 VPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDN---PVDLIATNITPT 967
Query: 1829 TITISWRTKTETITGFQV--DAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL 1886
+ W+ + + + G+T + + + R + L P T Y +Y
Sbjct: 968 EALLQWKAPVGEVENYVIVLTHFAVAGETILVDGVSEEFR---LVDLLPSTHYTATMYAT 1024
Query: 1887 NDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPRE 1946
N S + + ST +D P+NL T S L+SWQPPRA I Y++ Y+ +E
Sbjct: 1025 NGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSRKE 1084
Query: 1947 VVPRPRPGVTEATITGLEPGTEYTIYVIALKN 1978
++ T + GL T+YT+ + A ++
Sbjct: 1085 LIVDAED--TWIRLEGLLENTDYTVLLQAAQD 1114
Score = 274 bits (700), Expect = 9e-73
Identities = 208/812 (25%), Positives = 357/812 (43%), Gaps = 24/812 (2%)
Query: 902 PRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
P V P DL+ ++D + + W P AVT Y + P L G Q+ +
Sbjct: 321 PDCSAVAPPEDLRVAGISDRSIELEWDGP-MAVTEYVISYQPTALGGLQLQQRVPGDWSG 379
Query: 962 AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
+T L PG+TY V+AV S P+TA+ T L P LQF T++TV V+W P
Sbjct: 380 VTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPFS 439
Query: 1022 AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
G+ ++ V V+ + L+P EY V++VA+K SP +
Sbjct: 440 FSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSAS 499
Query: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTPAPR-----IGFKLGVRPSQGGEAPREVTSDSG 1136
+T+ G + +V++T + W P PR I K G+ +GG +
Sbjct: 500 VSTVIDGPT-QILVRDVSDTVAFVEWIP-PRAKVDFILLKYGLVGGEGGRTTFRLQPPLS 557
Query: 1137 SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE 1196
V L PG Y ++ +R E D+ + T + P NL + + T L + W+
Sbjct: 558 QYSVQALRPGSRYEVSVSAVRGTNESDS-ATTQFTTEIDAPKNLRVGSRTATS-LDLEWD 615
Query: 1197 RSTTPDITGYRITTTPTNGQQGNS-LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255
S ++ Y++ + G+Q + L + T +L PG EY V + V + ++
Sbjct: 616 NSEA-EVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQ 674
Query: 1256 SVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELS 1315
SVP + + P DL T ++ + W S + ++ + ++P + +E++
Sbjct: 675 SVPATMNARTELDSPRDLMVTASSETSISLIWT-KASGPIDHYRITFTP--SSGIASEVT 731
Query: 1316 ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFT 1375
+ + LT+L PG EY++SV++ + +S TG + + FS +T++S
Sbjct: 732 VPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVN 791
Query: 1376 VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGRE 1435
+ W P + + P E + ++ L L P TEY+V++VA++G
Sbjct: 792 ITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTV 851
Query: 1436 ESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT 1495
S ++G +T D P+D+ + T S+++SW P + YYR++Y T +
Sbjct: 852 TSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGR-LDSSV 910
Query: 1496 VPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQD 1555
VP + + TI+ L P +Y I++ +V GR + S+ I T +D P + T++
Sbjct: 911 VPNTVTEFTITRLNPATEYEISLNSVRGREE----SERICTLVHTAMDNPVDLIATNITP 966
Query: 1556 NSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQ 1615
++W V Y + T G +T E + L P+ Y ++YA
Sbjct: 967 TEALLQWKAPVGEVENYVIVLTHFAVAG--ETILVDGVSEEFRLVDLLPSTHYTATMYAT 1024
Query: 1616 NPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHE 1675
N S + T +D P L ++V S I+W+ P+ ++ Y +TY S + E
Sbjct: 1025 NGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSRKE 1084
Query: 1676 LFPAPDGEEDTAELQGLRPGSEYTVSVVALHD 1707
L D E+ L+GL ++YTV + A D
Sbjct: 1085 LI--VDAEDTWIRLEGLLENTDYTVLLQAAQD 1114
Score = 254 bits (650), Expect = 5e-67
Identities = 219/824 (26%), Positives = 351/824 (42%), Gaps = 26/824 (3%)
Query: 1000 PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR-QYNVGPSVSKYPLRNLQP 1058
P +L+ +D ++ + W P A +T Y ++ T G + Q V S + L+P
Sbjct: 329 PEDLRVAGISDRSIELEWDGPMA-VTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEP 387
Query: 1059 ASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFK 1116
Y +S+ A+ N S T T + T +TETT+ + W P G++
Sbjct: 388 GLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKT-ITETTVEVQWEPFSFSFDGWE 446
Query: 1117 LGVRPSQG-GEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLS 1175
+ P G +V SD S +GL PG EY+ + L++ Q R P V T +
Sbjct: 447 ISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKE-QARSPPTSASVSTVID 505
Query: 1176 PPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD 1235
PT + + DT V V W + + G +G + S +
Sbjct: 506 GPTQILVRDVSDT-VAFVEWIPPRAK--VDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQ 562
Query: 1236 NLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDL 1295
L PG Y VSV V+ ES + + P +LR + ++ + W + ++
Sbjct: 563 ALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDLEWDNSEA-EV 621
Query: 1296 TNFLVRYSPVKNE---EDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRG 1352
+ V YS + E E + I P+ A LT+L+PGTEY V +S+V +S P
Sbjct: 622 QEYKVVYSTLAGEQYHEVLVPRGIGPTTRAT-LTDLVPGTEYGVGISAVMNSQQSVPATM 680
Query: 1353 RQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNS 1412
+T LDSP + + + S ++ W I YRI P SG E VP R S
Sbjct: 681 NARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPS--SGIASEVTVPKDRTS 738
Query: 1413 ITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA 1472
TLT+L PG EY++S+ A GR++S T L T +S+ I+W P+
Sbjct: 739 YTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWSDPS 798
Query: 1473 VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSK 1532
+ Y + E ++ +K A + GL+P +Y + + AV G +S+
Sbjct: 799 PPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGT----VTSE 854
Query: 1533 PISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGP 1592
PI + T ID P + +++V +S+ V W P + YRV+ P G +
Sbjct: 855 PIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQ-VGRLDSSVVPN 913
Query: 1593 DQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAW 1652
TE TI L P EY +S+ + ES+ + T +D P L T++ + W
Sbjct: 914 TVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEALLQW 973
Query: 1653 ESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQ 1712
++P G+V Y + + + DG + L L P + YT ++ A + + S
Sbjct: 974 KAPVGEVENYVIVLTHFAVAGETILV--DGVSEEFRLVDLLPSTHYTATMYATNGPLTSG 1031
Query: 1713 PLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAP 1772
+ ST + P +L ++VT S W PP ++ Y + T K G KE+ +
Sbjct: 1032 TISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVL--TYKSTDGSRKELIVDA 1089
Query: 1773 DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSP 1816
+ + + + GL+ T Y V + A +DT S TT V P
Sbjct: 1090 EDTWIRLEGLLENTDYTVLLQAAQDTTWSSITSTAFTTGGRVFP 1133
Score = 245 bits (626), Expect = 3e-64
Identities = 215/816 (26%), Positives = 355/816 (43%), Gaps = 61/816 (7%)
Query: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
++W+ P +++Y++ ++P G + +PG + TI L+PG+ Y
Sbjct: 344 LEWDGPMA--VTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTY---------- 391
Query: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
++ + + S P+T+ T +TP T IT ++ V W S +
Sbjct: 392 ---NISVYAVISNILSLPITAKVATHLSTPQGLQFKT------ITETTVEVQWEPFSFSF 442
Query: 748 SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQ 807
G+ + + + + + +PS TS N L PG +YIVNV + E +S S S
Sbjct: 443 DGWEISF-IPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQA-RSPPTSASV 500
Query: 808 TTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYS-PSVEGSSTELNLPETANSVT 866
+T D P V V DT V W P+A + + Y EG T L + +
Sbjct: 501 STVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYS 560
Query: 867 LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
+ L+PG +Y +++ AV ES Q T + +P++L+ T + +
Sbjct: 561 VQALRPGSRYEVSVSAVRGTNESDSATTQFTT-------EIDAPKNLRVGSRTATSLDLE 613
Query: 927 WTPPESAVTGYRVDVIPVNLPGEHGQRLPISR----NTFAEVTGLSPGVTYYFKVFAVSH 982
W E+ V Y+ V+ L GE + + R T A +T L PG Y + AV +
Sbjct: 614 WDNSEAEVQEYK--VVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMN 671
Query: 983 GRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQY 1042
++S P T T+LD+P +L +++++ + WT I YR+T G +
Sbjct: 672 SQQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITF-TPSSGIASEV 730
Query: 1043 NVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT-GVFTTLQPGSSIPPYNTEVTET 1101
V + Y L +L+P +EY +S+ A +G Q+S ++T FT +P S + + + VT +
Sbjct: 731 TVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHL--HFSHVTSS 788
Query: 1102 TIVITWT----PAPRIGFKLGVRPSQGGEAPREVTSDSGS--IVVSGLTPGVEYVYTIQV 1155
++ ITW+ PA R+ L P E EV+ D+ V+ GL P EY+ + V
Sbjct: 789 SVNITWSDPSPPADRL--ILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNL-V 845
Query: 1156 LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNG 1215
G PIV + T + PP ++ + +N + VSW YR++ PT
Sbjct: 846 AVHGTVTSEPIVGSITTGIDPPKDITI-SNVTKDSVMVSWS-PPVASFDYYRVSYRPT-- 901
Query: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRF 1275
Q G VV + T L+P EY +S+ +V+ +ES I + A+ P DL
Sbjct: 902 QVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIA 961
Query: 1276 TNIGPDTMRVTW-APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY 1334
TNI P + W AP ++ ++ + V E + + L +LLP T Y
Sbjct: 962 TNITPTEALLQWKAPVGEVENYVIVLTHFAVAGE----TILVDGVSEEFRLVDLLPSTHY 1017
Query: 1335 VVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHP 1394
++ + S + T LD P + S++T S + W PRA I Y + +
Sbjct: 1018 TATMYATNGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTY-- 1075
Query: 1395 EHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVA 1430
+ G +E V I L L T+Y V + A
Sbjct: 1076 KSTDGSRKELIVDAEDTWIRLEGLLENTDYTVLLQA 1111
Score = 245 bits (625), Expect = 4e-64
Identities = 212/830 (25%), Positives = 350/830 (42%), Gaps = 34/830 (4%)
Query: 1351 RGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSR 1410
+G + + P + + I+ S + W P A +T Y I + P G + RVP
Sbjct: 319 QGPDCSAVAPPEDLRVAGISDRSIELEWDGPMA-VTEYVISYQPTALGGLQLQQRVPGDW 377
Query: 1411 NSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
+ +T+T L PG Y +S+ A+ S + + +T P+ L+ T T++ + W+
Sbjct: 378 SGVTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEP 437
Query: 1471 PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS 1530
+ + + I++ V VP ++ +GLKPG +Y + V A+ + SP +
Sbjct: 438 FSFSFDGWEISFIPKNNEGGVIA-QVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPT 496
Query: 1531 SKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTA 1590
S +S T ID P+Q+ V DV D V+W+P + V + G G T
Sbjct: 497 SASVS----TVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRL 552
Query: 1591 GPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKI 1650
P ++ +++ L+P Y VSV A + ES T ID PK L S+ +
Sbjct: 553 QPPLSQYSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDL 612
Query: 1651 AWESPQGQVSRYRVTYSS-PEDGIHE-LFPAPDGEEDTAELQGLRPGSEYTVSVVALHDD 1708
W++ + +V Y+V YS+ + HE L P G A L L PG+EY V + A+ +
Sbjct: 613 EWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNS 672
Query: 1709 MESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEI 1768
+S P T + +P DL T + TS+S WT + + YR+ TP +G E+
Sbjct: 673 QQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPS--SGIASEV 730
Query: 1769 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATET 1828
+ D +S ++ L +Y +SV A + S + V P + T +
Sbjct: 731 TVPKDRTSYTLTDLEPGAEYIISVTAERGRQQS--LESTVDAFTGFRPISHLHFSHVTSS 788
Query: 1829 TITISWRTKTETITGFQVDAVPANGQTPIQR-TIKPDVRSYTITGLQPGTDYKIYLYTLN 1887
++ I+W + ++ P + + + ++ R + GLQP T+Y + L ++
Sbjct: 789 SVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVH 848
Query: 1888 DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYE--KPGSPPR 1945
S P+V +T ID P ++ T +S++VSW PP A Y + Y + G
Sbjct: 849 GTVTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDS 908
Query: 1946 EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNL 2005
VVP VTE TIT L P TEY I + +++ ++SE + T + V L N+
Sbjct: 909 SVVPNT---VTEFTITRLNPATEYEISLNSVRGREESERICTLVHT-AMDNPVDLIATNI 964
Query: 2006 HGPEIL-----DVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVG--QQMIFEEHGFR 2058
E L V +TH G I + G S + V + +
Sbjct: 965 TPTEALLQWKAPVGEVENYVIVLTHFAV-AGETILVDGVSEEFRLVDLLPSTHYTATMYA 1023
Query: 2059 RTTPPTTATPIRHRPRPYPPNVGQEALSQT----TISWAPFQ-DTSEYIISCHPVGTDEE 2113
P T+ T + P A T ISW P + + Y+++ TD
Sbjct: 1024 TNGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTYK--STDGS 1081
Query: 2114 PLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSV 2163
+ V T L GL Y ++++A +D + T G V
Sbjct: 1082 RKELIVDAEDTWIRLEGLLENTDYTVLLQAAQDTTWSSITSTAFTTGGRV 1131
Score = 166 bits (421), Expect = 2e-40
Identities = 159/647 (24%), Positives = 273/647 (42%), Gaps = 42/647 (6%)
Query: 610 GPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIK 669
GP ++ + + ++W P+ + + +L++ G + L+ Y+++
Sbjct: 506 GPTQILVRDVSDTVAF--VEWIPPR-AKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQ 562
Query: 670 GLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVT 729
L+PG YE + +++ + FTT N G T S + S
Sbjct: 563 ALRPGSRYEVSVSAVRGTNESDSATTQFTT---EIDAPKNLRVGSRTATSLDLEWDNSEA 619
Query: 730 EITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVN 789
E+ V S T++G + L G P T + DL+PG +Y V
Sbjct: 620 EVQEYKVVYS------TLAGEQYHEVLVPRGIGP--------TTRATLTDLVPGTEYGVG 665
Query: 790 VYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSV 849
+ + + +QS+ + + T D+P D V +TSI + W++ PI YRI ++PS
Sbjct: 666 ISAVM-NSQQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPS- 723
Query: 850 EGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS 909
G ++E+ +P+ S TL+DL+PG +Y I++ A Q+S + T P S
Sbjct: 724 SGIASEVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISH---- 779
Query: 910 PRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSP 969
L F VT V I W+ P ++ P + E + + A + GL P
Sbjct: 780 ---LHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQP 836
Query: 970 GVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRL 1029
Y + AV S+P+ TT +D P ++ N T +V+V W+PP A YR+
Sbjct: 837 ATEYIVNLVAVHGTVTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRV 896
Query: 1030 TVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPK-ATGVFTTLQPG 1088
+ T+ G+ V +V+++ + L PA+EY +SL +++G +ES + T V T +
Sbjct: 897 SYRPTQVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMD-- 954
Query: 1089 SSIPPYNTEVTETTIVITW-TPAPRIGFKLGVRP--SQGGEAPREVTSDSGSIVVSGLTP 1145
+ + T +T T ++ W P + + V + GE V S + L P
Sbjct: 955 NPVDLIATNITPTEALLQWKAPVGEVENYVIVLTHFAVAGETIL-VDGVSEEFRLVDLLP 1013
Query: 1146 GVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITG 1205
Y T+ +G I T L PP NL L +SW+ +I
Sbjct: 1014 STHYTATMYA-TNGPLTSGTISTNFSTLLDPPANLTASEVTRQSAL-ISWQ-PPRAEIEN 1070
Query: 1206 YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD 1252
Y +T T+G + E +V A+ + + L +Y V + +D
Sbjct: 1071 YVLTYKSTDGSR---KELIVDAEDTWIRLEGLLENTDYTVLLQAAQD 1114
>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
Length = 4242
Score = 327 bits (837), Expect = 1e-88
Identities = 399/1802 (22%), Positives = 691/1802 (38%), Gaps = 313/1802 (17%)
Query: 616 ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
+T T S P+S + W PQ S + ++++ ++ GR + + G + T+ GL+PG
Sbjct: 1378 LTVTGSSPDSLSLFWTVPQGS-FDSFTVQYKDRD--GRPRAVRVGGKESEVTVGGLEPGH 1434
Query: 676 VYEGQLISIQQYGHQEVTRF-DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITAS 734
Y+ L YG E R + + P T +P P + +VT++T +
Sbjct: 1435 KYKMHL-----YGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLG-ELTVTDVTPN 1488
Query: 735 SFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQIS 794
S +SW F V+Y+ ++ +PQ + + + V + +L P RKY +N+Y +
Sbjct: 1489 SVGLSWTVPEGQFDSFIVQYK--DKDGQPQVVPVAADQREVTVYNLEPERKYKMNMYGL- 1545
Query: 795 EDGEQSLILSTSQTTAPDAPPDP----------------TVDQVDDTSIVVRWSRPQAPI 838
DG++ LS TAP PP P TV + S+ + W+ P+
Sbjct: 1546 HDGQRMGPLSVVIVTAP-LPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEF 1604
Query: 839 TGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898
+ + Y +G + + VT+ DL+P +Y ++ +++ + +PV ++ +T
Sbjct: 1605 DSFVVQYKDR-DGQPQVVPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKT 1663
Query: 899 TGTPRSDTVPSPR--DLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPI 956
+ PR +L + T + + WT PE + V + P Q +P+
Sbjct: 1664 VARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKDGP----QVVPV 1719
Query: 957 -SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL-----DAPT--------- 1001
VT L G Y F ++ + + PLTA TT+ D T
Sbjct: 1720 EGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLG 1779
Query: 1002 -NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060
LQ T ++V + WT P Q + + R GQP+ V S+ + + L PA
Sbjct: 1780 EELQVTTVTQNSVGLSWTVPEGQFDSF-VVQYKDRDGQPQVVPVEGSLREVSVPGLDPAH 1838
Query: 1061 EY--------------TVSLVAI-KGNQESPKATGVFTTLQPGSSIPPYNT-EVTETTIV 1104
Y +S VAI G +E+ T T P + E T T+
Sbjct: 1839 RYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLH 1898
Query: 1105 ITW--TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQ-- 1160
++W T F++ G + D I +SGL Y+ T+ DG+
Sbjct: 1899 LSWMVTEGEFDSFEIQYTDRDGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHV 1958
Query: 1161 ---ERDAPIVNKVVTPLSPPT-NLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQ 1216
+A V + P PPT P G LTV+ TPD ++ T GQ
Sbjct: 1959 GPVHVEALTVPEEEKPSEPPTATPEPPIKPRLGELTVT---DATPD--SLSLSWTVPEGQ 2013
Query: 1217 QGNSLEEVVHAD-----------QSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIP 1265
+ L + + D + T L P +Y +++Y + P+S +
Sbjct: 2014 FDHFLVQYRNGDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVT 2073
Query: 1266 A----VPPPT----------------DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPV 1305
A P PT +L T PD++ ++W P +F V+Y
Sbjct: 2074 AAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQG-RFDSFTVQYKDR 2132
Query: 1306 KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP-----LRGRQKTGLDS 1360
V + + ++ V + L PG +Y + + ++E P + ++ D+
Sbjct: 2133 DGRPQV--VRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDA 2190
Query: 1361 PTG------IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT 1414
P + DIT++S ++ W P + ++ ++ G+P+ RVP + +T
Sbjct: 2191 PLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQF--KNGDGQPKAVRVPGHEDGVT 2248
Query: 1415 LTNLTPGTEYVVSIVALNGREE----------SPLLIGQQSTVSDVP-----------RD 1453
++ L P +Y +++ +G + +P + + S P +
Sbjct: 2249 ISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEE 2308
Query: 1454 LEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVD 1513
L V ATP SL +SW P ++ + Y G+ + VPG + TISGL+P
Sbjct: 2309 LTVTDATPDSLSLSWTVPEGQFDHFLVQY--KNGDGQPKATRVPGHEDRVTISGLEPDNK 2366
Query: 1514 YTITVYAVTG---------------RGDSPASSKPISINYRTEIDKP--SQMQVTDVQDN 1556
Y + +Y G ++P+ ++P S+ ++P ++ VT +
Sbjct: 2367 YKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEP-SMEAPEPPEEPLLGELTVTGSSPD 2425
Query: 1557 SISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN 1616
S+S+ W + T K+ G + G +++E+T+ GL+P +Y + +Y +
Sbjct: 2426 SLSLSWTVPQGRFDSF--TVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLH 2483
Query: 1617 PSGESQPLVQTAVT----NIDRPKG-------------------LAFTDVDVDSIKIAWE 1653
P+ VT ++D L T DS+ ++W
Sbjct: 2484 EGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWT 2543
Query: 1654 SPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQP 1713
PQG+ + V Y DG + G+E ++GL PG +Y + + LH+ P
Sbjct: 2544 VPQGRFDSFTVQYKD-RDGRPQAVRV-GGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGP 2601
Query: 1714 LIGTQST--------AIPAPT----------DLKFTQVTPTSLSAQWTPPNVQLTGYRVR 1755
+ T A+P T +L T TP SLS WT P Q + V+
Sbjct: 2602 VSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHFLVQ 2661
Query: 1756 VTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV-VTTLENV 1814
+ G K + + V +SGL KY++++Y P + VT E
Sbjct: 2662 Y--RNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEE 2719
Query: 1815 SPPRRARVTDATE-----------------TTITISWRTKTETITGFQVDAVPANGQTPI 1857
+P T+A E ++++SW F V +G+ +
Sbjct: 2720 TPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYKDRDGRPQV 2779
Query: 1858 QRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI------DASTAIDAPS---- 1907
R ++ + T+ GL+PG YK++LY L++ R PV +A T P+
Sbjct: 2780 MR-VRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAVPTTTPE 2838
Query: 1908 --------NLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREV-VPRPRPGVTEA 1958
L TP+SL +SW P + ++++Y P+ V VP GV
Sbjct: 2839 PPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKVVRVPGHEDGV--- 2895
Query: 1959 TITGLEPGTEYTIYVIALKNNQKSEPL--IGRKKTDELPQLVTLPHPNLHGPEILDVPST 2016
TI+GLEP +Y + + Q+ P+ IG +E T P+ PE + P
Sbjct: 2896 TISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPT--EPSTEAPEPPEEPLL 2953
Query: 2017 VQKTPFVTHPG-------------------YDTGNG----IQLPG------TSGQQPSVG 2047
+ T + P Y +G +++ G G +P
Sbjct: 2954 GELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRGEESEVTVGGLEPGCK 3013
Query: 2048 QQM-IFEEHGFRRTTP--------------PTTATPIRHRPRPYPPNVGQEALSQTT--- 2089
+M ++ H +R P T A P P P +G+ ++ T
Sbjct: 3014 YKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTDATPDS 3073
Query: 2090 --ISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQ 2147
+SW + ++ + + G D +P RVPG T++GL Y + +
Sbjct: 3074 LSLSWMVPEGQFDHFLVQYRNG-DGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGG 3132
Query: 2148 QR 2149
QR
Sbjct: 3133 QR 3134
Score = 311 bits (798), Expect = 4e-84
Identities = 336/1513 (22%), Positives = 595/1513 (39%), Gaps = 190/1513 (12%)
Query: 616 ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
+T T S P+S + W PQ + ++++ ++ GR + + G + T++GL+PG
Sbjct: 2528 LTVTGSSPDSLSLSWTVPQ-GRFDSFTVQYKDRD--GRPQAVRVGGQESKVTVRGLEPGR 2584
Query: 676 VYEGQLISIQQYGHQ--EVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITA 733
Y+ L + + G + V+ T T T+T E P P + ++T+ T
Sbjct: 2585 KYKMHLYGLHE-GRRLGPVSAVGVTEDEAETTQAVPTMTPEP-PIKPRLGEL-TMTDATP 2641
Query: 734 SSFVVSWVSASDTVSGFRVEYELSEEGD-EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQ 792
S +SW F V+Y GD +P+ + +P V I L P KY +N+Y
Sbjct: 2642 DSLSLSWTVPEGQFDHFLVQYR---NGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYG 2698
Query: 793 I---SEDGEQSLILSTS-----------QTTAPDAPPDPTVDQVDDT-----SIVVRWSR 833
G S+I T+ T AP+ P +P + ++ T S+ + W+
Sbjct: 2699 FHGGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTI 2758
Query: 834 PQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPV- 892
PQ + + Y +G + + + VT+ L+PG +Y + +Y + E + PV
Sbjct: 2759 PQGHFDSFTVQYKDR-DGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVS 2817
Query: 893 ----------VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVI 942
Q T TP P +L + T +++ W PE + D
Sbjct: 2818 TVGVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEG-----QFDHF 2872
Query: 943 PVNLPGEHGQ----RLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD 998
V GQ R+P ++GL P Y ++ G+ P++ T +
Sbjct: 2873 LVQYRNGDGQPKVVRVP-GHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAE 2931
Query: 999 ----APTN----------------LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQ 1038
APT L + ++ + WT P+ + + + R G+
Sbjct: 2932 EETPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYK-DRDGR 2990
Query: 1039 PRQYNVGPSVSKYPLRNLQPASEYT--------------VSLVAIKGNQESPKATGVFTT 1084
P+ V S+ + L+P +Y VS V + ++ + T T
Sbjct: 2991 PQVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPT 3050
Query: 1085 LQPGSSIPPYNTEVTET-----TIVITW-TPAPRIG-FKLGVRPSQGGEAPREVTSDSGS 1137
+ P I P E+T T ++ ++W P + F + R G V
Sbjct: 3051 MTPEPPIKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDG 3110
Query: 1138 IVVSGLTPGVEYVYTIQVLRDGQERDAPI----VNKVVTPLSPPTNLHLEA-----NPDT 1188
+ +SGL P +Y + GQ R P+ V + TP PT EA P
Sbjct: 3111 VTISGLEPDHKYKMNLYGFHGGQ-RVGPVSAIGVTEEETP--SPTEPSTEAPEAPEEPLL 3167
Query: 1189 GVLTVSWERSTTPDITGYRIT---------TTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239
G LTV+ ++PD T T + G V ++S T L P
Sbjct: 3168 GELTVT---GSSPDSLSLSWTVPQGRFDSFTVQYKDRDGQPQVVRVRGEESEVTVGGLEP 3224
Query: 1240 GLEYNVSVYTVKDDKESVPISD--------TIIPAVPPPTDLRFTNIGPDTMRVTWAPPP 1291
G +Y + +Y + + + P+S T +P P +L + D++ ++W
Sbjct: 3225 GRKYKMHLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQ 3284
Query: 1292 SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR 1351
+FLV+Y + + + +S AV ++ L P +Y + + P+
Sbjct: 3285 G-PFDSFLVQYRDAQGQPQA--VPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVP 3341
Query: 1352 GRQKTGLDSPTG-----IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRV 1406
+T D+ + +D T +S + W P + +++ + GR + V
Sbjct: 3342 VEARTAPDTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDK--DGRLQVVPV 3399
Query: 1407 PHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV---SDVPR---DLEVVAAT 1460
++ +T+ L P +Y + L+GR+ + +T ++P +L V T
Sbjct: 3400 AANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEET 3459
Query: 1461 PTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
+SL +SW + + Y +T G + V + T T+ L+PG Y +Y
Sbjct: 3460 SSSLRLSWTVAQGPFDSFVVQYRDTDGQP--RAVPVAADQRTVTVEDLEPGKKYKFLLYG 3517
Query: 1521 VTG---------------RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPS 1565
+ G D+PA E + + VTD +S+ + W +
Sbjct: 3518 LLGGKRLGPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVA 3577
Query: 1566 SSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLV 1625
P + V NG P G DQ+++ I GL+P+ Y +Y + PL
Sbjct: 3578 QGPFDSFVVQYEDTNGQ-PQALLVDG-DQSKILISGLEPSTPYRFLLYGLHEGKRLGPLS 3635
Query: 1626 QTAVTNI---------DRPK--GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIH 1674
T + RP+ L+ TDV S+++ WE+P G + + + P
Sbjct: 3636 AEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTL 3695
Query: 1675 ELFPAP--------DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP--- 1723
E P P G +A L+ LR G+ Y++++ L ++ + GT T P
Sbjct: 3696 EPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLE 3755
Query: 1724 APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLM 1783
+P DL+F+++ TS W PP + ++V + P + + + + + + GL+
Sbjct: 3756 SPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEP-QSVQVDGQARTQKLQGLI 3814
Query: 1784 VATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITG 1843
+YEV+V +++ S P G +TT+ + P + R + TE + W+ +
Sbjct: 3815 PGARYEVTVVSVRGFEESEPLTGFLTTVPD--GPTQLRALNLTEGFAVLHWKPPQNPVDT 3872
Query: 1844 FQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI 1903
+ V V A G P+Q Y + L T+Y + L +SP I +T +
Sbjct: 3873 YDVQ-VTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGL 3931
Query: 1904 DAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGL 1963
+AP +L TP + L++W P R GY++ + PG +E++ G+T + GL
Sbjct: 3932 EAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEIL--LPGGITSHQLLGL 3989
Query: 1964 EPGTEYTIYVIAL 1976
P T Y + A+
Sbjct: 3990 FPSTSYNARLQAM 4002
Score = 311 bits (796), Expect = 6e-84
Identities = 411/1857 (22%), Positives = 694/1857 (37%), Gaps = 338/1857 (18%)
Query: 582 GVRYQCYCYG----------RGIGEWHCQPLQTYPSSSGPVEVFITE---TPSQPNSHPI 628
G +Y+ + YG +G Q +T P++ P+E + E T PNS +
Sbjct: 1433 GHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGL 1492
Query: 629 QWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYG 688
W P+ +I++++ K+ G+ + + T+ L+P Y+ + YG
Sbjct: 1493 SWTVPE-GQFDSFIVQYKDKD--GQPQVVPVAADQREVTVYNLEPERKYK-----MNMYG 1544
Query: 689 HQEVTRFD-FTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
+ R + + P+ T + P +VT+IT S +SW
Sbjct: 1545 LHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEF 1604
Query: 748 SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQ 807
F V+Y+ + +PQ + + + V IPDL P RKY ++ I + +S + ++
Sbjct: 1605 DSFVVQYK--DRDGQPQVVPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAK 1662
Query: 808 TTA-----PDAPP--------DPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSST 854
T A P APP DPT D S+ + W+ P+ + +V +G
Sbjct: 1663 TVARGDASPGAPPRLGELWVTDPTPD-----SLRLSWTVPEGQFDSF-VVQFKDKDGPQV 1716
Query: 855 ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET--------TGTPRSDT 906
+ + SVT++ L G +Y +Y + + P+ T TGT R
Sbjct: 1717 -VPVEGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRP-- 1773
Query: 907 VPSPR---DLQFVEVTDVKVTIMWTPPESAVTGYRV-----DVIPVNLPGEHGQRLPISR 958
P PR +LQ VT V + WT PE + V D P +P E R
Sbjct: 1774 -PKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQYKDRDGQPQVVPVEGSLRE---- 1828
Query: 959 NTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA--------QQTTKLDAPT--------- 1001
V GL P Y ++ + HG+ P++A + T+ APT
Sbjct: 1829 ---VSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPEPHLG 1885
Query: 1002 NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASE 1061
L T T+ + W + + + R GQ + +G + L L+
Sbjct: 1886 ELTVEEATSHTLHLSWMVTEGEFDSFEIQY-TDRDGQLQMVRIGGDRNDITLSGLESDHR 1944
Query: 1062 YTVSLVAIK-GNQESPKATGVFT-----------TLQPGSSIPPYNTEVTET-----TIV 1104
Y V+L G P T T P I P E+T T ++
Sbjct: 1945 YLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTATPEPPIKPRLGELTVTDATPDSLS 2004
Query: 1105 ITWT-PAPRIG-FKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQER 1162
++WT P + F + R G V + +SGL P +Y + GQ R
Sbjct: 2005 LSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQ-R 2063
Query: 1163 DAPIVNKVVTPLSP----PTNLHLEA-----NPDTGVLTVSWERSTTPDITGYRIT---- 1209
P+ VT PT +EA P G LTV+ ++PD T
Sbjct: 2064 MGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVT---GSSPDSLSLSWTVPQG 2120
Query: 1210 -----TTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTII 1264
T + G V ++S T L PG +Y + +Y + + + P+S +
Sbjct: 2121 RFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGV 2180
Query: 1265 PAVP------PPTDLRF-----TNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE 1313
A P LR +I D++ ++W P +FLV++ +
Sbjct: 2181 TAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEG-QFDHFLVQFK--NGDGQPKA 2237
Query: 1314 LSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR--GRQKTGLDS---------PT 1362
+ + ++ V ++ L P +Y +++ + P+ G G D PT
Sbjct: 2238 VRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPT 2297
Query: 1363 G----------IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNS 1412
+ +D T +S ++ W P + +++ ++ G+P+ RVP +
Sbjct: 2298 PEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQY--KNGDGQPKATRVPGHEDR 2355
Query: 1413 ITLTNLTPGTEYVVSIVALNG---------------REESPLLIGQQSTVSDVPRD---- 1453
+T++ L P +Y +++ +G EE+P + P +
Sbjct: 2356 VTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLG 2415
Query: 1454 -LEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGV 1512
L V ++P SL +SW P + + Y + G V V G +S T+ GL+PG
Sbjct: 2416 ELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVR--VGGEESEVTVGGLEPGR 2473
Query: 1513 DYTITVYAV-TGRGDSPASSKPISINYRTEIDKPS------------------QMQVTDV 1553
Y + +Y + GR P S+ ++ + PS ++ VT
Sbjct: 2474 KYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGS 2533
Query: 1554 QDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVY 1613
+S+S+ W + T K+ G + G ++++T+ GL+P +Y + +Y
Sbjct: 2534 SPDSLSLSWTVPQGRFDSF--TVQYKDRDGRPQAVRVGGQESKVTVRGLEPGRKYKMHLY 2591
Query: 1614 AQNPSGESQPLVQTAVTNID------------------RPKGLAFTDVDVDSIKIAWESP 1655
+ P+ VT + R L TD DS+ ++W P
Sbjct: 2592 GLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVP 2651
Query: 1656 QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLI 1715
+GQ + V Y + DG + P G ED + GL P +Y +++ H P+
Sbjct: 2652 EGQFDHFLVQYRNG-DGQPKAVRVP-GHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPIS 2709
Query: 1716 GTQSTAI----PAPTDLK----------------FTQVTPTSLSAQWTPPNVQLTGYRVR 1755
TA P+PT+L T +P SLS WT P + V+
Sbjct: 2710 VIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQ 2769
Query: 1756 VTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVS 1815
K++ G + + + + S V V GL KY++ +Y L + P V T +
Sbjct: 2770 Y--KDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAE 2827
Query: 1816 -----------PPRRAR-----VTDATETTITISWRTKTETITGFQVDAVPANGQTPIQR 1859
PP + R VTDAT ++++SW F V +GQ + R
Sbjct: 2828 TTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKVVR 2887
Query: 1860 TIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAID----APSN------- 1908
+ TI+GL+P YK+ LY + R P+ + TA + AP+
Sbjct: 2888 -VPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPTEPSTEAPE 2946
Query: 1909 ---------LRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEAT 1959
L ++P+SL +SW P+ R + ++Y+ P+ V R R +E T
Sbjct: 2947 PPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVV--RVRGEESEVT 3004
Query: 1960 ITGLEPGTEYTIYVIALKNNQKSEPLIG---------RKKTDELPQLVTLP--HPNLHGP 2008
+ GLEPG +Y +++ L Q+ P+ + T +P + P P L
Sbjct: 3005 VGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGEL 3064
Query: 2009 EILDVPSTVQKTPFVTHPG--------YDTGNG----IQLPG------TSGQQPSVGQQM 2050
+ D ++ G Y G+G +++PG SG +P +M
Sbjct: 3065 TVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKM 3124
Query: 2051 -IFEEHGFRRTTPPTT------ATPIRHRPRPYPPNVGQEAL-----------SQTTISW 2092
++ HG +R P + TP P P +E L ++SW
Sbjct: 3125 NLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSLSLSW 3184
Query: 2093 APFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 2149
Q + + D +P RV G + T+ GL G Y + + L + QR
Sbjct: 3185 TVPQGRFD-SFTVQYKDRDGQPQVVRVRGEESEVTVGGLEPGRKYKMHLYGLHEGQR 3240
Score = 310 bits (795), Expect = 8e-84
Identities = 399/1797 (22%), Positives = 682/1797 (37%), Gaps = 301/1797 (16%)
Query: 601 PLQTYPSSSGPVEVF------ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRW 654
P T PS P +T T S P+S + W PQ + ++++ ++ GR
Sbjct: 2080 PSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQ-GRFDSFTVQYKDRD--GRP 2136
Query: 655 KEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTG- 713
+ + G + T+ GL+PG Y+ L YG E R PV++ VT
Sbjct: 2137 QVVRVGGEESEVTVGGLEPGRKYKMHL-----YGLHEGRRVG--------PVSAVGVTAP 2183
Query: 714 -ETTPFSPLVAT---SESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGD-EPQYLDL 768
E +P +PL +V +IT+ S +SW F V+++ GD +P+ + +
Sbjct: 2184 EEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQFK---NGDGQPKAVRV 2240
Query: 769 PSTATSVNIPDLLPGRKYIVNVY---------QISEDG------EQSLILSTSQTTAPDA 813
P V I L P KY +N+Y +S G ++ + ++++ P+
Sbjct: 2241 PGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEP 2300
Query: 814 PPDPTVDQVDDT-----SIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLS 868
P P ++++ T S+ + W+ P+ + + Y +G +P + VT+S
Sbjct: 2301 PIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYKNG-DGQPKATRVPGHEDRVTIS 2359
Query: 869 DLQPGVQYNITIYAVEENQESTPV-----VIQQETTGTPRSDTVPSPRDLQFVEVTDVKV 923
L+P +Y + +Y Q PV +E T +P ++ +P + + ++ V
Sbjct: 2360 GLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTV 2419
Query: 924 T--------IMWTPPESAVTGYRVDVIPVNLPGEHGQRLPI---SRNTFAEVTGLSPGVT 972
T + WT P+ R D V G+ + + V GL PG
Sbjct: 2420 TGSSPDSLSLSWTVPQG-----RFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRK 2474
Query: 973 YYFKVFAVSHGRESKPL-----TAQQTTKLDAPT------------------NLQFVNET 1009
Y ++ + GR P+ TA Q + P+ L +
Sbjct: 2475 YKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSS 2534
Query: 1010 DSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLV-- 1067
++ + WT P+ + + + R G+P+ VG SK +R L+P +Y + L
Sbjct: 2535 PDSLSLSWTVPQGRFDSFTVQYK-DRDGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGL 2593
Query: 1068 ----------AIKGNQESPKATGVFTTLQPGSSIPPYNTEVTET-----TIVITWT-PAP 1111
A+ ++ + T T+ P I P E+T T ++ ++WT P
Sbjct: 2594 HEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEG 2653
Query: 1112 RIG-FKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPI---- 1166
+ F + R G V + +SGL P +Y + GQ R PI
Sbjct: 2654 QFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQ-RVGPISVIG 2712
Query: 1167 VNKVVTPLSPPTNLHLEA-----NPDTGVLTVSWERSTTPDITGYRIT---------TTP 1212
V PT L EA P G LTV+ ++PD T T
Sbjct: 2713 VTAAEEETPSPTELSTEAPEPPEEPLLGELTVT---GSSPDSLSLSWTIPQGHFDSFTVQ 2769
Query: 1213 TNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIP------- 1265
+ G V ++S T L PG +Y + +Y + + + P+S +
Sbjct: 2770 YKDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETT 2829
Query: 1266 -AVPPPT----------DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAEL 1314
AVP T +L T+ PD++ ++W P +FLV+Y + V
Sbjct: 2830 QAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEG-QFDHFLVQYRNGDGQPKVVR- 2887
Query: 1315 SISPSDNAVVLTNLLPGTEYV--------------VSVSSVYEQHESTPLRGRQKTGLDS 1360
+ ++ V ++ L P +Y +SV V E TP T
Sbjct: 2888 -VPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPTEPSTEAPE 2946
Query: 1361 PTG------IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT 1414
P + + + +S ++ W P+ + +++ GRP+ RV + +T
Sbjct: 2947 PPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDR--DGRPQVVRVRGEESEVT 3004
Query: 1415 LTNLTPGTEYVVSIVALN-GREESPL-LIG------QQSTVSDVPR------------DL 1454
+ L PG +Y + + L+ G+ P+ +G + T VP +L
Sbjct: 3005 VGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGEL 3064
Query: 1455 EVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDY 1514
V ATP SL +SW P ++ + Y G+ + VPG + TISGL+P Y
Sbjct: 3065 TVTDATPDSLSLSWMVPEGQFDHFLVQY--RNGDGQPKAVRVPGHEDGVTISGLEPDHKY 3122
Query: 1515 TITVYAVTG-------------RGDSPASSKPISINYRTEIDKP--SQMQVTDVQDNSIS 1559
+ +Y G ++P+ ++P S ++P ++ VT +S+S
Sbjct: 3123 KMNLYGFHGGQRVGPVSAIGVTEEETPSPTEP-STEAPEAPEEPLLGELTVTGSSPDSLS 3181
Query: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619
+ W + V ++G P + G +++E+T+ GL+P +Y + +Y +
Sbjct: 3182 LSWTVPQGRFDSFTVQYKDRDGQ-PQVVRVRG-EESEVTVGGLEPGRKYKMHLYGLHEGQ 3239
Query: 1620 ESQPLVQTAVTNI--------DRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPED 1671
P+ +T R LA V DS+ ++W QG + V Y +
Sbjct: 3240 RVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQYRDAQ- 3298
Query: 1672 GIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAI---PAPT-- 1726
G + P G+ + GL P +Y + L + P+ TA P+P
Sbjct: 3299 GQPQAVPV-SGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTKPSPRLG 3357
Query: 1727 DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVAT 1786
+L T TP S+ WT P + + V+ K+K G ++ + +A + V V GL +
Sbjct: 3358 ELTVTDATPDSVGLSWTVPEGEFDSFVVQY--KDKDGRLQVVPVAANQREVTVQGLEPSR 3415
Query: 1787 KYEVSVYALKDTLTSRPAQGVVTT--LENVSPPRRARVTDATETT--ITISWRTKTETIT 1842
KY +Y L P TT LE PP +T A ET+ + +SW
Sbjct: 3416 KYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLSWTVAQGPFD 3475
Query: 1843 GFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA 1902
F V +GQ P + D R+ T+ L+PG YK LY L R PV TA
Sbjct: 3476 SFVVQYRDTDGQ-PRAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKRLGPVSALGMTA 3534
Query: 1903 IDAPSNLRFLA-------------------TTPNSLLVSWQPPRARITGYIIKYEKPGSP 1943
+ + LA TTP+S+ +SW + ++++YE
Sbjct: 3535 PEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFVVQYEDTNGQ 3594
Query: 1944 PREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP--QLVTLP 2001
P+ ++ ++ I+GLEP T Y + L ++ PL T P Q
Sbjct: 3595 PQALLVDGDQ--SKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQTSEES 3652
Query: 2002 HPNLHGPEILDVPSTVQKTPFVTHPG-YDT---GNGIQLPGTSGQQPSVGQQMIFEEHGF 2057
P L + DV ++ + + PG +D+ G+ P T P Q G
Sbjct: 3653 RPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQRELMVPGT 3712
Query: 2058 RRTT-----------------------------PPTTATPIRHRPRPYPPNVGQEALSQT 2088
R + T +P+ PR + +E +
Sbjct: 3713 RHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEIRE--TSA 3770
Query: 2089 TISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALK 2145
++W P ++ + + EP +V G + + L GL GA Y + V +++
Sbjct: 3771 KVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVR 3827
Score = 303 bits (775), Expect = 2e-81
Identities = 362/1616 (22%), Positives = 610/1616 (37%), Gaps = 283/1616 (17%)
Query: 619 TPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYE 678
T P+S + W P+ ++++++ K+ + + GH S T+ L G Y
Sbjct: 1683 TDPTPDSLRLSWTVPE-GQFDSFVVQFKDKDGP---QVVPVEGHERSVTVTPLDAGRKYR 1738
Query: 679 GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
L + D TT + S + TG P P + VT +T +S +
Sbjct: 1739 FLLYGLLGKKRHGPLTADGTTEARS----AMDDTGTKRPPKPRLGEELQVTTVTQNSVGL 1794
Query: 739 SWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISED-- 796
SW F V+Y+ + +PQ + + + V++P L P +Y + +Y +
Sbjct: 1795 SWTVPEGQFDSFVVQYK--DRDGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKR 1852
Query: 797 -GEQSLILSTS-------QTTAPDAP-PDP-----TVDQVDDTSIVVRWSRPQAPITGYR 842
G S + T+ +TTAP P P+P TV++ ++ + W + +
Sbjct: 1853 VGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFE 1912
Query: 843 IVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET---- 898
I Y+ +G + + N +TLS L+ +Y +T+Y + + PV ++ T
Sbjct: 1913 IQYTDR-DGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEE 1971
Query: 899 -------TGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRV-----DVIP--V 944
T TP P +L + T +++ WT PE + V D P V
Sbjct: 1972 EKPSEPPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAV 2031
Query: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT--- 1001
+PG H + + IS GL P Y ++ G+ P++ T + T
Sbjct: 2032 RVPG-HEEGVTIS--------GLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSP 2082
Query: 1002 -----------------NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNV 1044
L + ++ + WT P+ + + + R G+P+ V
Sbjct: 2083 TEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYK-DRDGRPQVVRV 2141
Query: 1045 GPSVSKYPLRNLQPASEYTVSLVAI-KGNQESP-KATGVFTTLQPGSSIPPYNT------ 1096
G S+ + L+P +Y + L + +G + P A GV + P
Sbjct: 2142 GGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMT 2201
Query: 1097 --EVTETTIVITWT-PAPRIG-FKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYT 1152
++T ++ ++WT P + F + + G V + +SGL P +Y
Sbjct: 2202 VRDITSDSLSLSWTVPEGQFDHFLVQFKNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMN 2261
Query: 1153 IQVLRDGQ----------------ERDAPIVNKVVTPLSPPTNLHLE------ANPDTGV 1190
+ GQ E AP + TP PP LE A PD+
Sbjct: 2262 LYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTP-EPPIKPRLEELTVTDATPDS-- 2318
Query: 1191 LTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
L++SW T P+ NG G V + T L P +Y +++Y
Sbjct: 2319 LSLSW---TVPEGQFDHFLVQYKNGD-GQPKATRVPGHEDRVTISGLEPDNKYKMNLYGF 2374
Query: 1251 KDDKESVPISDTIIPAV----PPPTD----------------LRFTNIGPDTMRVTWAPP 1290
+ P+S + A P PT+ L T PD++ ++W P
Sbjct: 2375 HGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVP 2434
Query: 1291 PSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY---------------- 1334
+F V+Y V + ++ V + L PG +Y
Sbjct: 2435 QG-RFDSFTVQYKDRDGRPQVVR--VGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPV 2491
Query: 1335 -VVSVSSVYEQHESTPLRGRQKTGLDSPTG------IDFSDITANSFTVHWIAPRATITG 1387
V V++ E + TP T P + + + +S ++ W P+
Sbjct: 2492 STVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDS 2551
Query: 1388 YRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN-GREESPL-LIG--- 1442
+ +++ GRP+ RV + +T+ L PG +Y + + L+ GR P+ +G
Sbjct: 2552 FTVQYKDR--DGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGPVSAVGVTE 2609
Query: 1443 -QQSTVSDVPR------------DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNS 1489
+ T VP +L + ATP SL +SW P ++ + Y G+
Sbjct: 2610 DEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHFLVQY--RNGDG 2667
Query: 1490 PVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGR---------GDSPASSK-PISINYR 1539
+ VPG + TISGL+P Y + +Y G G + A + P
Sbjct: 2668 QPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPSPTELS 2727
Query: 1540 TEIDKP------SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPD 1593
TE +P ++ VT +S+S+ W + V ++G P + G +
Sbjct: 2728 TEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYKDRDGR-PQVMRVRG-E 2785
Query: 1594 QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT------------------NIDRP 1635
++E+T+ GL+P +Y + +Y + P+ VT N R
Sbjct: 2786 ESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAVPTTTPEPPNKPRL 2845
Query: 1636 KGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPG 1695
L TD DS+ ++W P+GQ + V Y + DG ++ P G ED + GL P
Sbjct: 2846 GELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNG-DGQPKVVRVP-GHEDGVTISGLEPD 2903
Query: 1696 SEYTVSVVALHDDMESQPLIGTQSTAI----PAPTD----------------LKFTQVTP 1735
+Y +++ H P+ TA PAPT+ L T +P
Sbjct: 2904 HKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEPLLGELTVTGSSP 2963
Query: 1736 TSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYAL 1795
SLS WT P + + V+ K++ G + + + + S V V GL KY++ +Y L
Sbjct: 2964 DSLSLSWTIPQGRFDSFTVQY--KDRDGRPQVVRVRGEESEVTVGGLEPGCKYKMHLYGL 3021
Query: 1796 KDTLTSRPAQGVVTTLEN-------------VSPPRRAR-----VTDATETTITISWRTK 1837
+ P V T PP + R VTDAT ++++SW
Sbjct: 3022 HEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTDATPDSLSLSWMVP 3081
Query: 1838 TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1897
F V +GQ R + TI+GL+P YK+ LY + R PV
Sbjct: 3082 EGQFDHFLVQYRNGDGQPKAVR-VPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSA 3140
Query: 1898 DASTAIDAPS------------------NLRFLATTPNSLLVSWQPPRARITGYIIKYEK 1939
T + PS L ++P+SL +SW P+ R + ++Y+
Sbjct: 3141 IGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKD 3200
Query: 1940 PGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP 1995
P+ V R R +E T+ GLEPG +Y +++ L Q+ P+ T LP
Sbjct: 3201 RDGQPQVV--RVRGEESEVTVGGLEPGRKYKMHLYGLHEGQRVGPVSTVGITAPLP 3254
Score = 290 bits (743), Expect = 9e-78
Identities = 386/1760 (21%), Positives = 652/1760 (37%), Gaps = 290/1760 (16%)
Query: 624 NSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLIS 683
+S + W P+ +++++ KN G+ K +PGH + TI GL+P Y+ L
Sbjct: 2208 DSLSLSWTVPE-GQFDHFLVQF--KNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYG 2264
Query: 684 IQQYGHQEVTRFDFT--TTSTSTPVTSNTVTGETTPFSPLVATSE--SVTEITASSFVVS 739
+G Q V T + T TP P+ E +VT+ T S +S
Sbjct: 2265 F--HGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLS 2322
Query: 740 WVSASDTVSGFRVEYELSEEGD-EPQYLDLPSTATSVNIPDLLPGRKYIVNVY------- 791
W F V+Y+ GD +P+ +P V I L P KY +N+Y
Sbjct: 2323 WTVPEGQFDHFLVQYK---NGDGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQR 2379
Query: 792 --QISEDGEQSLILSTSQTT-----APDAPPDPTVDQVDDT-----SIVVRWSRPQAPIT 839
+S G + T T AP+ P +P + ++ T S+ + W+ PQ
Sbjct: 2380 VGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFD 2439
Query: 840 GYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETT 899
+ + Y +G + + + VT+ L+PG +Y + +Y + E + PV T
Sbjct: 2440 SFTVQYKDR-DGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTA 2498
Query: 900 GTPRSDTVPSPRD----------------LQFVEVTDVKVTIMWTPPESAVTGYRVDVIP 943
D PSP + L + +++ WT P+ R D
Sbjct: 2499 PQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTVPQG-----RFDSFT 2553
Query: 944 VNLPGEHGQRLPI---SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAP 1000
V G+ + + + V GL PG Y ++ + GR P++A T+ +A
Sbjct: 2554 VQYKDRDGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEAE 2613
Query: 1001 TN------------------LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQY 1042
T L + T ++ + WT P Q + L GQP+
Sbjct: 2614 TTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHF-LVQYRNGDGQPKAV 2672
Query: 1043 NVGPSVSKYPLRNLQPASEYTVSLVAIKGNQ---------------ESPKATGVFTTLQP 1087
V + L+P +Y ++L G Q E+P T + +T P
Sbjct: 2673 RVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPSPTEL-STEAP 2731
Query: 1088 GSSIPPYNTEVTET-----TIVITWT-PAPRI-GFKLGVRPSQGGEAPREVTSDSGSIVV 1140
P E+T T ++ ++WT P F + + G V + + V
Sbjct: 2732 EPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYKDRDGRPQVMRVRGEESEVTV 2791
Query: 1141 SGLTPGVEYVYTIQVLRDGQ-----------ERDAPIVNKVVTPLSPPTNLHLEANPDTG 1189
GL PG +Y + L +G+ E +A V T P N P G
Sbjct: 2792 GGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAVPTTTPEPPN-----KPRLG 2846
Query: 1190 VLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHAD-----------QSSCTFDNLS 1238
LTV+ TPD ++ GQ + L + + D + T L
Sbjct: 2847 ELTVT---DATPD--SLSLSWMVPEGQFDHFLVQYRNGDGQPKVVRVPGHEDGVTISGLE 2901
Query: 1239 PGLEYNVSVYTVKDDKESVPIS---------DTIIPAVP------PPTD-----LRFTNI 1278
P +Y +++Y + PIS +T P P PP + L T
Sbjct: 2902 PDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEPLLGELTVTGS 2961
Query: 1279 GPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSV 1338
PD++ ++W P +F V+Y V + ++ V + L PG +Y + +
Sbjct: 2962 SPDSLSLSWTIPQG-RFDSFTVQYKDRDGRPQVVR--VRGEESEVTVGGLEPGCKYKMHL 3018
Query: 1339 SSVYEQHESTPL--------RGRQKTGLDSPT------------GIDFSDITANSFTVHW 1378
++E P+ + +T PT + +D T +S ++ W
Sbjct: 3019 YGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTDATPDSLSLSW 3078
Query: 1379 IAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG----- 1433
+ P + +++ + G+P+ RVP + +T++ L P +Y +++ +G
Sbjct: 3079 MVPEGQFDHFLVQYR--NGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVG 3136
Query: 1434 --------REESPLLIGQQSTVSDVPRD-----LEVVAATPTSLLISWDAPAVTVRYYRI 1480
EE+P + + P + L V ++P SL +SW P + +
Sbjct: 3137 PVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTV 3196
Query: 1481 TYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV-TGRGDSPASSKPISINYR 1539
Y + G V V G +S T+ GL+PG Y + +Y + G+ P S+ I+
Sbjct: 3197 QYKDRDGQPQVVR--VRGEESEVTVGGLEPGRKYKMHLYGLHEGQRVGPVSTVGITAPLP 3254
Query: 1540 TEID---KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1596
T + + ++ V V +S+ + W + P + V G P +G D
Sbjct: 3255 TPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQYRDAQGQ-PQAVPVSG-DLRA 3312
Query: 1597 MTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNID-----RPKGLAFTDVDVDSIKIA 1651
+ + GL P +Y ++ P+ A T D R L TD DS+ ++
Sbjct: 3313 VAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTKPSPRLGELTVTDATPDSVGLS 3372
Query: 1652 WESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMES 1711
W P+G+ + V Y +DG ++ P + + +QGL P +Y + L
Sbjct: 3373 WTVPEGEFDSFVVQYKD-KDGRLQVVPVAANQREVT-VQGLEPSRKYRFLLYGLSGRKRL 3430
Query: 1712 QPLIGTQSTAI------PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPM 1765
P+ +TA P +L + T +SL WT + V+ ++ G
Sbjct: 3431 GPISADSTTAPLEKELPPHLGELTVAEETSSSLRLSWTVAQGPFDSFVVQY--RDTDGQP 3488
Query: 1766 KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTL------------EN 1813
+ + +A D +V V L KY+ +Y L P + T E
Sbjct: 3489 RAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKRLGPVSALGMTAPEEDTPAPELAPEA 3548
Query: 1814 VSPPRRAR-----VTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSY 1868
PP R VTD T ++ +SW F V NGQ P + D
Sbjct: 3549 PEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFVVQYEDTNGQ-PQALLVDGDQSKI 3607
Query: 1869 TITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP------------SNLRFLATTP 1916
I+GL+P T Y+ LY L++ R P+ + +T + AP S L T
Sbjct: 3608 LISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGL-APAGQTSEESRPRLSQLSVTDVTT 3666
Query: 1917 NSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPR-------PGVTE-ATITGLEPGTE 1968
+SL ++W+ P +++++ P E PRP PG A + L GT
Sbjct: 3667 SSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTL 3726
Query: 1969 YTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHP-- 2026
Y++ + L+ K++ + G +T L ++ P +L EI + + V P +
Sbjct: 3727 YSLTLYGLRGPHKADSIQGTART--LSPVLESPR-DLQFSEIRETSAKVNWMPPPSRADS 3783
Query: 2027 ---GYDTGNG-----IQLPGTSGQQPSVG-------QQMIFEEHGFRRTTPPTT-ATPIR 2070
Y +G +Q+ G + Q G + + GF + P T T +
Sbjct: 3784 FKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVP 3843
Query: 2071 HRPRPYPPNVGQEALSQT----TISWAPFQDTSE-YIISCHPVGTDEEPLQFRVPGTSTS 2125
P AL+ T + W P Q+ + Y + G PLQ PG++
Sbjct: 3844 DGPTQL------RALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAP--PLQAETPGSAVD 3895
Query: 2126 ATLTGLTRGATYNIIVEALK 2145
L L Y V L+
Sbjct: 3896 YPLHDLVLHTNYTATVRGLR 3915
Score = 277 bits (708), Expect = 1e-73
Identities = 328/1543 (21%), Positives = 584/1543 (37%), Gaps = 211/1543 (13%)
Query: 616 ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
+T T S P+S + W PQ + ++++ ++ GR + + G + T+ GL+PG
Sbjct: 2417 LTVTGSSPDSLSLSWTVPQ-GRFDSFTVQYKDRD--GRPQVVRVGGEESEVTVGGLEPGR 2473
Query: 676 VYEGQLISIQQYGHQEVTRFD-FTTTSTSTPVTSNTVTGETT---------PFSPLVATS 725
Y+ L YG E R +T + P T T P PL+
Sbjct: 2474 KYKMHL-----YGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGEL 2528
Query: 726 ESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRK 785
+VT + S +SW F V+Y+ + PQ + + + V + L PGRK
Sbjct: 2529 -TVTGSSPDSLSLSWTVPQGRFDSFTVQYK--DRDGRPQAVRVGGQESKVTVRGLEPGRK 2585
Query: 786 YIVNVYQISED---GEQSLILSTSQ---------TTAPDAPPDPTVDQVDDT-----SIV 828
Y +++Y + E G S + T T P+ P P + ++ T S+
Sbjct: 2586 YKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLS 2645
Query: 829 VRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQE 888
+ W+ P+ + + Y +G + +P + VT+S L+P +Y + +Y Q
Sbjct: 2646 LSWTVPEGQFDHFLVQYRNG-DGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQR 2704
Query: 889 STPVVI-----QQETTGTPRSDTVPSPRDLQFVEVTDVKVT--------IMWTPPESAVT 935
P+ + +E T +P + +P + + ++ VT + WT P+
Sbjct: 2705 VGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQG--- 2761
Query: 936 GYRVDVIPVNLPGEHGQ-RLPISRNTFAEVT--GLSPGVTYYFKVFAVSHGRESKPLTAQ 992
D V G+ ++ R +EVT GL PG Y ++ + GR P++
Sbjct: 2762 --HFDSFTVQYKDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTV 2819
Query: 993 QTTKLDAPTN------------------LQFVNETDSTVLVRWTPPRAQITGYRLTVGLT 1034
T+ +A T L + T ++ + W P Q + L
Sbjct: 2820 GVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHF-LVQYRN 2878
Query: 1035 RRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTL--------- 1085
GQP+ V + L+P +Y ++L G Q + + T
Sbjct: 2879 GDGQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPT 2938
Query: 1086 QPGSSIP-----PYNTEVTET-----TIVITWT-PAPRI-GFKLGVRPSQGGEAPREVTS 1133
+P + P P E+T T ++ ++WT P R F + + G V
Sbjct: 2939 EPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRG 2998
Query: 1134 DSGSIVVSGLTPGVEYVYTIQVLRDGQERD--------APIVNKVVTPLSPPTNLHLEAN 1185
+ + V GL PG +Y + L +GQ AP T P
Sbjct: 2999 EESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIK 3058
Query: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHAD-----------QSSCTF 1234
P G LTV+ TPD ++ GQ + L + + D + T
Sbjct: 3059 PRLGELTVT---DATPD--SLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTI 3113
Query: 1235 DNLSPGLEYNVSVYTVKDDKESVPISDTIIPA--VPPPTD----------------LRFT 1276
L P +Y +++Y + P+S + P PT+ L T
Sbjct: 3114 SGLEPDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVT 3173
Query: 1277 NIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVV 1336
PD++ ++W P +F V+Y + V + ++ V + L PG +Y +
Sbjct: 3174 GSSPDSLSLSWTVPQG-RFDSFTVQYKDRDGQPQVVR--VRGEESEVTVGGLEPGRKYKM 3230
Query: 1337 SVSSVYEQHESTPLRGRQKTG-LDSPTGID-------FSDITANSFTVHWIAPRATITGY 1388
+ ++E P+ T L +P ++ + +T++S + W + +
Sbjct: 3231 HLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSF 3290
Query: 1389 RIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTV 1447
+++ G+P+ V ++ ++ L P +Y + L NG+ P+ + ++
Sbjct: 3291 LVQYRDAQ--GQPQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAP 3348
Query: 1448 SDVPR----DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
P +L V ATP S+ +SW P + + Y + G +Q V ++
Sbjct: 3349 DTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDKDGR--LQVVPVAANQREV 3406
Query: 1504 TISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVK 1561
T+ GL+P Y +Y ++GR P S+ + E+ ++ V + +S+ +
Sbjct: 3407 TVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLS 3466
Query: 1562 WLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYV------------ 1609
W + P + V ++ G + DQ +T+E L+P +Y
Sbjct: 3467 WTVAQGPFDSFVVQY--RDTDGQPRAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKRL 3524
Query: 1610 --VSVYAQNPSGESQPLVQTAVTNIDRPKG-----LAFTDVDVDSIKIAWESPQGQVSRY 1662
VS E P + A + P+ L TD DS++++W QG +
Sbjct: 3525 GPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSF 3584
Query: 1663 RVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAI 1722
V Y L DG++ + GL P + Y + LH+ PL +T +
Sbjct: 3585 VVQYEDTNGQPQALLV--DGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGL 3642
Query: 1723 -----------PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR--------VTPKEKTG 1763
P + L T VT +SL W P + +R + P +
Sbjct: 3643 APAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPL 3702
Query: 1764 PMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV-SPPRRARV 1822
+E+ + S V+ L T Y +++Y L+ + QG TL V PR +
Sbjct: 3703 LQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQF 3762
Query: 1823 TDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIY 1882
++ ET+ ++W F+V A+G P + R+ + GL PG Y++
Sbjct: 3763 SEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVT 3822
Query: 1883 LYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGS 1942
+ ++ S P+ +T D P+ LR L T ++ W+PP+ + Y ++ PG+
Sbjct: 3823 VVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGA 3882
Query: 1943 PPREVVPRPRPG-VTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
PP + PG + + L T YT V L+ + P
Sbjct: 3883 PPLQA---ETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSP 3922
Score = 264 bits (675), Expect = 7e-70
Identities = 383/1746 (21%), Positives = 664/1746 (38%), Gaps = 263/1746 (15%)
Query: 616 ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
+T T + P+S + W P+ +++++ KN G+ K +PGH + TI GL+P
Sbjct: 2309 LTVTDATPDSLSLSWTVPE-GQFDHFLVQY--KNGDGQPKATRVPGHEDRVTISGLEPDN 2365
Query: 676 VYEGQLISIQQYGHQEV---TRFDFTTTSTSTPV-TSNTVTGETTPFSPLVATSESVTEI 731
Y+ L +G Q V + T TP T ++ P PL+ +VT
Sbjct: 2366 KYKMNLYGF--HGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGEL-TVTGS 2422
Query: 732 TASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVY 791
+ S +SW F V+Y+ + PQ + + + V + L PGRKY +++Y
Sbjct: 2423 SPDSLSLSWTVPQGRFDSFTVQYK--DRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLY 2480
Query: 792 QI-----------------SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT-----SIVV 829
+ ED +++ + T AP P +P + ++ T S+ +
Sbjct: 2481 GLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSL 2540
Query: 830 RWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES 889
W+ PQ + + Y +G + + + VT+ L+PG +Y + +Y + E +
Sbjct: 2541 SWTVPQGRFDSFTVQYKDR-DGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRL 2599
Query: 890 TPV-----------VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYR 938
PV Q T TP P +L + T +++ WT PE +
Sbjct: 2600 GPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEG-----Q 2654
Query: 939 VDVIPVNLPGEHGQ----RLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQT 994
D V GQ R+P ++GL P Y ++ G+ P++
Sbjct: 2655 FDHFLVQYRNGDGQPKAVRVP-GHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGV 2713
Query: 995 TKLDAPT--------------------NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLT 1034
T + T L + ++ + WT P+ + +
Sbjct: 2714 TAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYK-D 2772
Query: 1035 RRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAI-KGNQESPKAT-GVF------TTLQ 1086
R G+P+ V S+ + L+P +Y + L + +G + P +T GV T
Sbjct: 2773 RDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAV 2832
Query: 1087 PGSSIPPYN---------TEVTETTIVITW-TPAPRIG-FKLGVRPSQGGEAPREVTSDS 1135
P ++ P N T+ T ++ ++W P + F + R G V
Sbjct: 2833 PTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKVVRVPGHE 2892
Query: 1136 GSIVVSGLTPGVEYVYTIQVLRDGQERDAPI----VNKVVTPLSPPTNLHLEA-----NP 1186
+ +SGL P +Y + GQ R PI V PT EA P
Sbjct: 2893 DGVTISGLEPDHKYKMNLYGFHGGQ-RVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEP 2951
Query: 1187 DTGVLTVSWERSTTPDITGYRIT---------TTPTNGQQGNSLEEVVHADQSSCTFDNL 1237
G LTV+ ++PD T T + G V ++S T L
Sbjct: 2952 LLGELTVT---GSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRGEESEVTVGGL 3008
Query: 1238 SPGLEYNVSVYTV-----------------KDDKESVPISDTIIPAVPPPT---DLRFTN 1277
PG +Y + +Y + KD+ E+ T+ P P +L T+
Sbjct: 3009 EPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTD 3068
Query: 1278 IGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVS 1337
PD++ ++W P +FLV+Y + + + ++ V ++ L P +Y ++
Sbjct: 3069 ATPDSLSLSWMVPEG-QFDHFLVQYR--NGDGQPKAVRVPGHEDGVTISGLEPDHKYKMN 3125
Query: 1338 ------------VSSVYEQHESTPLRGRQKTGL-DSPTGIDFSDITA-----NSFTVHWI 1379
VS++ E TP T ++P ++T +S ++ W
Sbjct: 3126 LYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSLSLSWT 3185
Query: 1380 APRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPL 1439
P+ + +++ G+P+ RV + +T+ L PG +Y + + L+ +
Sbjct: 3186 VPQGRFDSFTVQYKDR--DGQPQVVRVRGEESEVTVGGLEPGRKYKMHLYGLHEGQR--- 3240
Query: 1440 LIGQQSTVSDV----------PR--DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGG 1487
+G STV PR +L V A T S+ +SW + + Y + G
Sbjct: 3241 -VGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQYRDAQG 3299
Query: 1488 NSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID-KPS 1546
Q V G +SGL P Y ++ + + P+ + RT D KPS
Sbjct: 3300 QP--QAVPVSGDLRAVAVSGLDPARKYKFLLFGL----QNGKRHGPVPVEARTAPDTKPS 3353
Query: 1547 ----QMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGL 1602
++ VTD +S+ + W + V K+G + +Q E+T++GL
Sbjct: 3354 PRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDKDGR--LQVVPVAANQREVTVQGL 3411
Query: 1603 QPTVEYVVSVYAQNPSGESQPLVQ---TAVTNIDRPKGLAFTDVDVD---SIKIAWESPQ 1656
+P+ +Y +Y + P+ TA + P L V + S++++W Q
Sbjct: 3412 EPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLSWTVAQ 3471
Query: 1657 GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIG 1716
G + V Y DG P ++ T ++ L PG +Y + L P+
Sbjct: 3472 GPFDSFVVQYRDT-DGQPRAVPVA-ADQRTVTVEDLEPGKKYKFLLYGLLGGKRLGPVSA 3529
Query: 1717 TQSTA-------------IPAPTD------LKFTQVTPTSLSAQWTPPNVQLTGYRVRVT 1757
TA P P + L T TP S+ W+ + V+
Sbjct: 3530 LGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFVVQY- 3588
Query: 1758 PKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTT------- 1810
++ G + + + D S +++SGL +T Y +Y L + P TT
Sbjct: 3589 -EDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQ 3647
Query: 1811 LENVSPPRRAR--VTDATETTITISWRTKTETITGFQVD-AVPA------NGQTPIQRTI 1861
S PR ++ VTD T +++ ++W F + VP+ + + +QR +
Sbjct: 3648 TSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQREL 3707
Query: 1862 K-PDVR-SYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST---AIDAPSNLRFLATTP 1916
P R S + L+ GT Y + LY L ++ + A T +++P +L+F
Sbjct: 3708 MVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEIRE 3767
Query: 1917 NSLLVSWQPPRARITGYIIKYE-KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 1975
S V+W PP +R + + Y+ G P+ V + + + GL PG Y + V++
Sbjct: 3768 TSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQK--LQGLIPGARYEVTVVS 3825
Query: 1976 LKNNQKSEPLIGRKKT--DELPQL----VTLPHPNLHGPEILDVPSTVQKTPFVTHPGYD 2029
++ ++SEPL G T D QL +T LH + T VT PG
Sbjct: 3826 VRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQ--VTAPGAP 3883
Query: 2030 TGNGIQLPGTSGQQP----SVGQQMIFEEHGFR--RTTPPTTATPIRHRPRPYPPNVGQE 2083
+ PG++ P + G R T P + T P +
Sbjct: 3884 PLQA-ETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLEAPRDLEAKEV 3942
Query: 2084 ALSQTTISWA-PFQDTSEYIISCH-PVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIV 2141
++W P + Y++S H P G ++E L +PG TS L GL +YN +
Sbjct: 3943 TPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEIL---LPGGITSHQLLGLFPSTSYNARL 3999
Query: 2142 EALKDQ 2147
+A+ Q
Sbjct: 4000 QAMWGQ 4005
Score = 248 bits (633), Expect = 5e-65
Identities = 392/1803 (21%), Positives = 661/1803 (36%), Gaps = 326/1803 (18%)
Query: 629 QWNAPQPSHISKYILRWRPKNSVGRWK-EATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
+W P P + Y +++ P A +P ++Y +GL PG Y+
Sbjct: 768 EWT-PAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQ--------- 817
Query: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
VT TS P + T P V +T ++ + W+ V
Sbjct: 818 ----VTVRALRGTSWGLPASKTITTMIDGP------QDLRVVAVTPTTLELGWLRPQAEV 867
Query: 748 SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNV---------YQIS---E 795
F V Y + G++ L++P A + DL+PG +Y+V V Y S
Sbjct: 868 DRFVVSYVSA--GNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRAN 925
Query: 796 DGEQSL-ILSTSQTTAPDAPPDPTVDQV------------------DDTS-IVVRWSRPQ 835
G L +L T+ P P Q D+T + V W+
Sbjct: 926 TGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVWTAQP 985
Query: 836 APITGYRI-VYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN-QESTPVV 893
+++ + P G+ E+ LP + PG Y ++++ V + S P++
Sbjct: 986 DTFAYFQLRMRVPEGPGAHEEV-LPGDVRQALVPPPPPGTPYELSLHGVPPGGKPSDPII 1044
Query: 894 IQ------QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRV-----DVI 942
Q +E G +S P +L + T + + WT PE + + D
Sbjct: 1045 YQGIMDKDEEKPG--KSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDGQ 1102
Query: 943 PVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA------QQTTK 996
P +P E QR + +T L PG Y F ++ + PL A Q
Sbjct: 1103 PQVVPVEGPQRSAV-------ITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPS 1155
Query: 997 LDAPT---NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPL 1053
P NL + T ++ + WT P Q + + R G+P+ V + +
Sbjct: 1156 PGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYR-DRDGRPQVVPVEGPERSFVV 1214
Query: 1054 RNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN-------------TEVTE 1100
+L P +Y +L I + T TT PP T VT
Sbjct: 1215 SSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTP 1274
Query: 1101 TTIVITWTPA--PRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD 1158
++ ++WT A P F + + +QG V D + V GL P +Y + LR
Sbjct: 1275 DSLRLSWTVAQGPFDSFMVQYKDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLR- 1333
Query: 1159 GQERDAPIVNKVVTPLSP---------PTNLHLEA-----NPDTGVLTVSWERSTTPDIT 1204
G++R P VV +P PT L EA P G LTV+ ++PD
Sbjct: 1334 GRQRVGP--ESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVT---GSSPDSL 1388
Query: 1205 GYRIT---------TTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255
T T + G V +S T L PG +Y + +Y + + +
Sbjct: 1389 SLFWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQR 1448
Query: 1256 SVPISDTIIPA-----VPPPTD---------LRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301
P+S + A PP T+ L T++ P+++ ++W P +F+V+
Sbjct: 1449 VGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEG-QFDSFIVQ 1507
Query: 1302 YSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR---------- 1351
Y + V + ++ V + NL P +Y +++ +++ PL
Sbjct: 1508 YKDKDGQPQV--VPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPP 1565
Query: 1352 ----GRQKTGLDSPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRV 1406
K L+ G + +DIT +S + W P + +++ G+P+ V
Sbjct: 1566 APATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDR--DGQPQVVPV 1623
Query: 1407 PHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSD------VPR--DLEVV 1457
+ +T+ +L P +Y + + +G+ SP+ + ++ PR +L V
Sbjct: 1624 AADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVT 1683
Query: 1458 AATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTIT 1517
TP SL +SW P + + + + G V V G + + T++ L G Y
Sbjct: 1684 DPTPDSLRLSWTVPEGQFDSFVVQFKDKDGPQVVP---VEGHERSVTVTPLDAGRKYRFL 1740
Query: 1518 VYAVTGRGDSPASSKPISINYRTEID--------KP---SQMQVTDVQDNSISVKWLPSS 1566
+Y + G+ + + R+ +D KP ++QVT V NS+ + W
Sbjct: 1741 LYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPE 1800
Query: 1567 SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ 1626
+ V ++G P G E+++ GL P Y + +Y + P+
Sbjct: 1801 GQFDSFVVQYKDRDGQ-PQVVPVEG-SLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISA 1858
Query: 1627 TAVT----------NIDRPKG-------LAFTDVDVDSIKIAWESPQGQVSRYRVTYSSP 1669
A+T P L + ++ ++W +G+ + + Y+
Sbjct: 1859 VAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTD- 1917
Query: 1670 EDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLI------------GT 1717
DG ++ G+ + L GL Y V++ D P+
Sbjct: 1918 RDGQLQMVRI-GGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSE 1976
Query: 1718 QSTAIPAPT------DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLA 1771
TA P P +L T TP SLS WT P Q + V+ + G K + +
Sbjct: 1977 PPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQY--RNGDGQPKAVRVP 2034
Query: 1772 PDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV-VTTLENVSP---------PRRAR 1821
V +SGL KY++++Y P V VT E +P P A
Sbjct: 2035 GHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAE 2094
Query: 1822 --------VTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGL 1873
VT ++ ++++SW F V +G+ + R + + T+ GL
Sbjct: 2095 EPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVR-VGGEESEVTVGGL 2153
Query: 1874 QPGTDYKIYLYTLNDNARSSPVVIDASTA-----IDAP------SNLRFLATTPNSLLVS 1922
+PG YK++LY L++ R PV TA DAP + T +SL +S
Sbjct: 2154 EPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLS 2213
Query: 1923 WQPPRARITGYIIKYEKPGSPPREV-VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 1981
W P + ++++++ P+ V VP GV TI+GLEP +Y + + Q+
Sbjct: 2214 WTVPEGQFDHFLVQFKNGDGQPKAVRVPGHEDGV---TISGLEPDHKYKMNLYGFHGGQR 2270
Query: 1982 SEP-----LIGRKKTDELPQLVTLP-------HPNLH-------GPEILDVPSTVQKTPF 2022
P L K +E+ T P P L P+ L + TV + F
Sbjct: 2271 VGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQF 2330
Query: 2023 VTH--PGYDTGNG----IQLPG------TSGQQPSVGQQM-IFEEHGFRRTTP------- 2062
H Y G+G ++PG SG +P +M ++ HG +R P
Sbjct: 2331 -DHFLVQYKNGDGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVT 2389
Query: 2063 ------PTTATPIRHRPR-PYPPNVGQEALS-----QTTISWAPFQDTSEYIISCHPVGT 2110
P+ P P P P +G+ ++ ++SW Q + +
Sbjct: 2390 AAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFD-SFTVQYKDR 2448
Query: 2111 DEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQP 2170
D P RV G + T+ GL G Y + + L + +R VG G+ P
Sbjct: 2449 DGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRR---------VGPVSTVGVTAP 2499
Query: 2171 TDD 2173
+D
Sbjct: 2500 QED 2502
Score = 221 bits (562), Expect = 9e-57
Identities = 311/1456 (21%), Positives = 533/1456 (36%), Gaps = 232/1456 (15%)
Query: 900 GTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGE--HGQRLPIS 957
G + VP+ ++ + + V WTP V Y + IP R+P S
Sbjct: 742 GEDCGEEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSS 801
Query: 958 RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRW 1017
+ + + GL+PG Y V A+ P + TT +D P +L+ V T +T+ + W
Sbjct: 802 ASAYDQ-RGLAPGQEYQVTVRALRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGW 860
Query: 1018 TPPRAQITGYRLTVGLTRRGQPR-QYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
P+A++ R V G R + V P L +L P EY V++ A +G S
Sbjct: 861 LRPQAEVD--RFVVSYVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSY 918
Query: 1077 KAT----------GVFTTLQPGSSIPPYNTEVTETTIV---------------------- 1104
A+ G+ T P T+ + ++
Sbjct: 919 PASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLR 978
Query: 1105 ITWTPAPR--IGFKLGVRPSQGGEAPREV-TSDSGSIVVSGLTPGVEYVYTIQVLRDGQE 1161
+ WT P F+L +R +G A EV D +V PG Y ++ + G +
Sbjct: 979 VVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPGGK 1038
Query: 1162 RDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS-------TTPDITGYRITTTPTN 1214
PI+ + + P G LTV+ S T P+ +
Sbjct: 1039 PSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPE-GEFDSFVIQYK 1097
Query: 1215 GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPI--------SDTIIPA 1266
+ G V Q S +L PG +Y +Y K P+ P
Sbjct: 1098 DRDGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPG 1157
Query: 1267 VPPPT-DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1325
PP +L T+ PD++ ++W P F+V+Y V + + + + V+
Sbjct: 1158 TPPHLGNLWVTDPTPDSLHLSWTVPEG-QFDTFMVQYRDRDGRPQV--VPVEGPERSFVV 1214
Query: 1326 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG------------LDSPT--GIDFSDITA 1371
++L P +Y ++ + + PL T L+ P + + +T
Sbjct: 1215 SSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTP 1274
Query: 1372 NSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL 1431
+S + W + + +++ + G+P+ V N +T+ L P +Y +++ L
Sbjct: 1275 DSLRLSWTVAQGPFDSFMVQY--KDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGL 1332
Query: 1432 NGREE--------------------SPLLIGQQSTVS---DVPRDLEVVAATPTSLLISW 1468
GR+ SP +G ++ S + +L V ++P SL + W
Sbjct: 1333 RGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFW 1392
Query: 1469 DAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV-TGRGDS 1527
P + + + Y + G + V G +S T+ GL+PG Y + +Y + G+
Sbjct: 1393 TVPQGSFDSFTVQYKDRDGRP--RAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVG 1450
Query: 1528 PASSKPISINYRTEI---------DKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTP 1578
P S+ ++ + E + ++ VTDV NS+ + W + V
Sbjct: 1451 PVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYKD 1510
Query: 1579 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE---------SQPLVQTAV 1629
K+ G + DQ E+T+ L+P +Y +++Y + + PL
Sbjct: 1511 KD--GQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPA 1568
Query: 1630 TNIDRPK------GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFP-APDG 1682
T +P L TD+ DS+ ++W P+G+ + V Y DG ++ P A D
Sbjct: 1569 TEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKD-RDGQPQVVPVAADQ 1627
Query: 1683 EEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST---------AIPAPTDLKFTQV 1733
E T + L P +Y + + D P+ T A P +L T
Sbjct: 1628 REVT--IPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDP 1685
Query: 1734 TPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVY 1793
TP SL WT P Q + V+ K+K GP + + + SV V+ L KY +Y
Sbjct: 1686 TPDSLRLSWTVPEGQFDSFVVQF--KDKDGP-QVVPVEGHERSVTVTPLDAGRKYRFLLY 1742
Query: 1794 ALKDTLTSRP--------AQGVVTTLENVSPPR-----RARVTDATETTITISWRTKTET 1840
L P A+ + PP+ +VT T+ ++ +SW
Sbjct: 1743 GLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQ 1802
Query: 1841 ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAS 1900
F V +GQ P ++ +R ++ GL P YK+ LY L+ R P+ A
Sbjct: 1803 FDSFVVQYKDRDGQ-PQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAI 1861
Query: 1901 TAIDAPSNLRFLATTP-----------------NSLLVSWQPPRARITGYIIKY-EKPGS 1942
TA + A TP ++L +SW + I+Y ++ G
Sbjct: 1862 TAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTDRDGQ 1921
Query: 1943 PPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL------IGRKKTDELPQ 1996
+ R + T++GLE Y + + + + P+ + ++ P
Sbjct: 1922 LQMVRIGGDR---NDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPP 1978
Query: 1997 LVTLPHPNLH-----------GPEILDVPSTVQKTPFVTH--PGYDTGNG----IQLPG- 2038
T P P + P+ L + TV + F H Y G+G +++PG
Sbjct: 1979 TAT-PEPPIKPRLGELTVTDATPDSLSLSWTVPEGQF-DHFLVQYRNGDGQPKAVRVPGH 2036
Query: 2039 -----TSGQQPSVGQQM-IFEEHGFRRTTPPTTA--------TPIRHRPRPYPPNVGQEA 2084
SG +P +M ++ HG +R P + TP P P +E
Sbjct: 2037 EEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEP 2096
Query: 2085 L-----------SQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTR 2133
L ++SW Q + + D P RV G + T+ GL
Sbjct: 2097 LLGELTVTGSSPDSLSLSWTVPQGRFD-SFTVQYKDRDGRPQVVRVGGEESEVTVGGLEP 2155
Query: 2134 GATYNIIVEALKDQQR 2149
G Y + + L + +R
Sbjct: 2156 GRKYKMHLYGLHEGRR 2171
Score = 217 bits (553), Expect = 9e-56
Identities = 302/1380 (21%), Positives = 519/1380 (37%), Gaps = 230/1380 (16%)
Query: 822 VDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTEL--NLPETANSVTLSDLQPGVQYNIT 879
+++T++ W+ P+ Y I + P+ EG+S +P +A++ L PG +Y +T
Sbjct: 760 LEETTVRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVT 819
Query: 880 IYAVEENQESTPVVIQQETTGTPRSDTVPS----PRDLQFVEVTDVKVTIMWTPPESAVT 935
+ A ++ + G P S T+ + P+DL+ V VT + + W P++ V
Sbjct: 820 VRA-----------LRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQAEVD 868
Query: 936 GYRVDVIPVNLPGEHGQRLPISRNTFAE-VTGLSPGVTYYFKVFA-----------VSHG 983
+ V + G RL + +T L PGV Y V A V
Sbjct: 869 RFVVSYVSA---GNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRAN 925
Query: 984 RESKPLTAQQTTKLDAPTNLQFVNETDSTVL----------------------VRWTPPR 1021
S PL TT P+ + +L V WT
Sbjct: 926 TGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVWTAQP 985
Query: 1022 AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIK--GNQESPKA- 1078
++L + + + + V + + P + Y +SL + G P
Sbjct: 986 DTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPGGKPSDPIIY 1045
Query: 1079 TGVF--TTLQPG-SSIPPYNTEVTET-----TIVITWT-PAPRI-GFKLGVRPSQGGEAP 1128
G+ +PG SS PP E+T T ++++ WT P F + + G
Sbjct: 1046 QGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDGQPQV 1105
Query: 1129 REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV-VTPLSPPTNLHLEANPD 1187
V S V++ L PG +Y + + G++R P+V + + P S P+ P
Sbjct: 1106 VPVEGPQRSAVITSLDPGRKYKFVLYGF-VGKKRHGPLVAEAKILPQSDPSP---GTPPH 1161
Query: 1188 TGVLTVSWERSTTPDITGYRITTTPTNGQ-----------QGNSLEEVVHADQSSCTFDN 1236
G L W TPD ++ T GQ G V + S +
Sbjct: 1162 LGNL---WVTDPTPD--SLHLSWTVPEGQFDTFMVQYRDRDGRPQVVPVEGPERSFVVSS 1216
Query: 1237 LSPGLEYNVSVYTVKDDKESVPIS--DTIIP--AVPPPT----------DLRFTNIGPDT 1282
L P +Y +++ + + K P++ T P PP +L T + PD+
Sbjct: 1217 LDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDS 1276
Query: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLP------------ 1330
+R++W +F+V+Y + + + ++ +N V + L P
Sbjct: 1277 LRLSWTVAQG-PFDSFMVQYKDAQGQPQA--VPVAGDENEVTVPGLDPDRKYKMNLYGLR 1333
Query: 1331 -----GTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG--------IDFSDITANSFTVH 1377
G E VV+ ++ E + TP + G ++P + + + +S ++
Sbjct: 1334 GRQRVGPESVVAKTAPQEDVDETP--SPTELGTEAPESPEEPLLGELTVTGSSPDSLSLF 1391
Query: 1378 WIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEY------------- 1424
W P+ + + +++ GRPR RV + +T+ L PG +Y
Sbjct: 1392 WTVPQGSFDSFTVQYKDR--DGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRV 1449
Query: 1425 -VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG 1483
VS V + ++ +S + +L V TP S+ +SW P + + Y
Sbjct: 1450 GPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYK 1509
Query: 1484 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV-TGRGDSPAS----SKPISINY 1538
+ G Q V + T+ L+P Y + +Y + G+ P S + P+
Sbjct: 1510 DKDGQP--QVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAP 1567
Query: 1539 RTEIDKP------SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGP 1592
TE KP ++ VTD+ +S+ + W + V K+ G +
Sbjct: 1568 ATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQY--KDRDGQPQVVPVAA 1625
Query: 1593 DQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA--VTNIDRPKG-------LAFTDV 1643
DQ E+TI L+P+ +Y ++ P+ A V D G L TD
Sbjct: 1626 DQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDP 1685
Query: 1644 DVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVV 1703
DS++++W P+GQ + V + +DG ++ P +G E + + L G +Y +
Sbjct: 1686 TPDSLRLSWTVPEGQFDSFVVQFKD-KDG-PQVVPV-EGHERSVTVTPLDAGRKYRFLLY 1742
Query: 1704 ALHDDMESQPLIGTQSTAI------------PAP---TDLKFTQVTPTSLSAQWTPPNVQ 1748
L PL +T P P +L+ T VT S+ WT P Q
Sbjct: 1743 GLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQ 1802
Query: 1749 LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVV 1808
+ V+ K++ G + + + V V GL A +Y++ +Y L P V
Sbjct: 1803 FDSFVVQY--KDRDGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVA 1860
Query: 1809 -------TTLENVSPPRRA--------RVTDATETTITISWRTKTETITGFQVDAVPANG 1853
T E +P A V +AT T+ +SW F++ +G
Sbjct: 1861 ITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTDRDG 1920
Query: 1854 QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDA------------ST 1901
Q + R I D T++GL+ Y + LY +D PV ++A T
Sbjct: 1921 QLQMVR-IGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPT 1979
Query: 1902 AIDAP------SNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREV-VPRPRPG 1954
A P L TP+SL +SW P + ++++Y P+ V VP G
Sbjct: 1980 ATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEEG 2039
Query: 1955 VTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVP 2014
V TI+GLEP +Y + + Q+ P+ T + + P++ PE + P
Sbjct: 2040 V---TISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEP 2096
Score = 111 bits (278), Expect = 7e-24
Identities = 140/616 (22%), Positives = 223/616 (36%), Gaps = 97/616 (15%)
Query: 1613 YAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDG 1672
YA GE P ++ G+ ++ +++ W G V Y + + +G
Sbjct: 740 YAGEDCGEEVPTIE----------GMRMHLLEETTVRTEWTPAPGPVDAYEIQFIPTTEG 789
Query: 1673 IHELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFT 1731
F A +A + +GL PG EY V+V AL P T +T I P DL+
Sbjct: 790 ASPPFTARVPSSASAYDQRGLAPGQEYQVTVRALRGTSWGLPASKTITTMIDGPQDLRVV 849
Query: 1732 QVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS 1791
VTPT+L W P ++ R V+ + + P++ +++ LM +Y V+
Sbjct: 850 AVTPTTLELGWLRPQAEVD--RFVVSYVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVT 907
Query: 1792 VYALKDTLTSRPAQ----------GVVTTLENVSPP--------------------RRAR 1821
V A + S PA G++ T + P R
Sbjct: 908 VTAERGRAVSYPASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELR 967
Query: 1822 VTDATET-TITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYK 1880
V ET + + W + +T FQ+ G + + DVR + PGT Y+
Sbjct: 968 VLGRDETGRLRVVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYE 1027
Query: 1881 IYLYTLNDNAR-SSPVVIDASTAID--------APSNLRFLAT---TPNSLLVSWQPPRA 1928
+ L+ + + S P++ D P L L T +SLL+ W P
Sbjct: 1028 LSLHGVPPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEG 1087
Query: 1929 RITGYIIKY-EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIG 1987
++I+Y ++ G P +VVP P A IT L+PG +Y + ++ PL+
Sbjct: 1088 EFDSFVIQYKDRDGQP--QVVPVEGP-QRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVA 1144
Query: 1988 RKKTDELPQLVTLPHPNLH---------GPEILDVPSTVQKTPFVTH--PGYDTGNGIQL 2036
K LPQ P H P+ L + TV + F T D Q+
Sbjct: 1145 EAKI--LPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYRDRDGRPQV 1202
Query: 2037 PGTSGQQPSVGQQMIFEEHGFRRT-------------TPPTTATPIRHRPRPYPPNVGQE 2083
G + S + +H +R T T T P R P P + Q
Sbjct: 1203 VPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQP 1262
Query: 2084 ALSQTTI----------SWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTR 2133
L + T+ SW Q + + + +P V G T+ GL
Sbjct: 1263 LLGELTVTGVTPDSLRLSWTVAQGPFDSFMVQYK-DAQGQPQAVPVAGDENEVTVPGLDP 1321
Query: 2134 GATYNIIVEALKDQQR 2149
Y + + L+ +QR
Sbjct: 1322 DRKYKMNLYGLRGRQR 1337
>gi|62988324 tenascin N [Homo sapiens]
Length = 1299
Score = 315 bits (806), Expect = 4e-85
Identities = 238/810 (29%), Positives = 379/810 (46%), Gaps = 28/810 (3%)
Query: 1177 PTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDN 1236
P L L N + +L VSWE S+ D Y ++ P G++ + + V +Q S
Sbjct: 265 PQGLQLLKNTEDSLL-VSWEPSSQVD--HYLLSYYPL-GKELSGKQIQVPKEQHSYEILG 320
Query: 1237 LSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLT 1296
L PG +Y V++ VK++ S P + T+ +++ V W P S ++
Sbjct: 321 LLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENP-STEVD 379
Query: 1297 NFLVRYSPVKNEEDVAELSISPSDNAVV---LTNLLPGTEYVVSVSSVYEQHESTPLRGR 1353
+ +RY P+ +E VAE+++ S + +T L PGTEY ++V + + E P+
Sbjct: 380 YYKLRYGPMTGQE-VAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLN 438
Query: 1354 QKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSI 1413
+T +DSPT + +T ++ TV W +A I Y +R+ G +E V +S
Sbjct: 439 GRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSA--DGDTKEMAVHKDESST 496
Query: 1414 TLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAV 1473
LT L PG Y V + A G + S T D P +L T + ISWD
Sbjct: 497 VLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTDRVTENTATISWDPVQA 556
Query: 1474 TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKP 1533
T+ Y + Y + + +E V +S+ ++GL+PGV+YT+ V+A G +S K
Sbjct: 557 TIDKYVVRY-TSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRES----KK 611
Query: 1534 ISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPD 1593
N T+ID P + V +N +V W P + + Y V T + G T+ G +
Sbjct: 612 ADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYT--SAGGETREVPVGKE 669
Query: 1594 QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWE 1653
Q+ + GL+P +EY+V V+AQ ES+ A T+ID P+ L V + ++W+
Sbjct: 670 QSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSWD 729
Query: 1654 SPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE-LQGLRPGSEYTVSVVALHDDMESQ 1712
+ + RY V Y+S +DG E P G+E ++ L GLRPG EYTV V A ES+
Sbjct: 730 PVRATIDRYVVRYTSAKDG--ETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESK 787
Query: 1713 PLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAP 1772
T I +P +L VT + + W P + Y V T G +E+ +
Sbjct: 788 KADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYT--SANGETREVPVGK 845
Query: 1773 DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITI 1832
+ SS V++GL +Y V V+A K S+ A T + P+ TE T+
Sbjct: 846 EQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQT--EIDGPKNLVTDWVTENMATV 903
Query: 1833 SWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARS 1892
SW TI + V A+G+T + + + S +TGL+PG +Y ++++ S
Sbjct: 904 SWDPVQATIDKYMVRYTSADGETR-EVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQES 962
Query: 1893 SPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPR 1952
A T +D P NLR A T + +++W PP A+I GYI+ Y+ P +E+
Sbjct: 963 KKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQFPDGTVKEMQLGRE 1022
Query: 1953 PGVTEATITGLEPGTEYTIYVIALKNNQKS 1982
+ GLE G Y + ++A K ++S
Sbjct: 1023 D--QRFALQGLEQGATYPVSLVAFKGGRRS 1050
Score = 313 bits (801), Expect = 2e-84
Identities = 226/760 (29%), Positives = 348/760 (45%), Gaps = 31/760 (4%)
Query: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326
V P L+ D++ V+W P +D ++L+ Y P+ E ++ + ++ +
Sbjct: 262 VVTPQGLQLLKNTEDSLLVSWEPSSQVD--HYLLSYYPLGKELSGKQIQVPKEQHSYEIL 319
Query: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATIT 1386
LLPGT+Y+V++ +V + S+P T L +D T NS V W P +
Sbjct: 320 GLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEVD 379
Query: 1387 GYRIRHHPEHFSGRP-REDRVPHS---RNSITLTNLTPGTEYVVSIVALNGREESPLLIG 1442
Y++R+ P +G+ E VP S ++ +T L PGTEY +++V + G E ++
Sbjct: 380 YYKLRYGP--MTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILL 437
Query: 1443 QQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKST 1502
T D P ++ T + +SWD + Y + Y G++ +E V +S+
Sbjct: 438 NGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDT--KEMAVHKDESS 495
Query: 1503 ATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW 1562
++GLKPG Y + V+A G SK N TEID P+ + V +N+ ++ W
Sbjct: 496 TVLTGLKPGEAYKVYVWAERGN----QGSKKADTNALTEIDSPANLVTDRVTENTATISW 551
Query: 1563 LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1622
P + + Y V T + T+ G +Q+ + GL+P VEY V V+AQ ES+
Sbjct: 552 DPVQATIDKYVVRYTSADDQ-ETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESK 610
Query: 1623 PLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDG 1682
A T+ID PK L V + ++W+ Q + +Y V Y+S E+ P G
Sbjct: 611 KADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGETREV---PVG 667
Query: 1683 EEDTAE-LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQ 1741
+E ++ L GLRPG EY V V A D ES+ T I +P +L +VT +
Sbjct: 668 KEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVS 727
Query: 1742 WTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1801
W P + Y VR T K G +E+ + + SS V++GL +Y V V+A K S
Sbjct: 728 WDPVRATIDRYVVRYT-SAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQES 786
Query: 1802 RPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTI 1861
+ A T ++ P+ TE T T+SW TI + V ANG+T + +
Sbjct: 787 KKADTKAQT--DIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETR-EVPV 843
Query: 1862 KPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLV 1921
+ S +TGL+PG +Y ++++ N S A T ID P NL T N V
Sbjct: 844 GKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATV 903
Query: 1922 SWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 1981
SW P +A I Y+++Y REV T +TGL PG EY ++V A K Q+
Sbjct: 904 SWDPVQATIDKYMVRYTSADGETREVPVGKEHSST--VLTGLRPGMEYMVHVWAQKGAQE 961
Query: 1982 SEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTP 2021
S KK D Q P NL + + TP
Sbjct: 962 S------KKADTKAQTELDPPRNLRPSAVTQSGGILTWTP 995
Score = 304 bits (778), Expect = 8e-82
Identities = 240/848 (28%), Positives = 381/848 (44%), Gaps = 35/848 (4%)
Query: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN--LPGEHGQRLPISRNTFAEV 964
V +P+ LQ ++ T+ + + W P S V Y + P+ L G+ Q +P ++++ E+
Sbjct: 262 VVTPQGLQLLKNTEDSLLVSWEP-SSQVDHYLLSYYPLGKELSGKQIQ-VPKEQHSY-EI 318
Query: 965 TGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQI 1024
GL PG Y + V + S P TT L +ET++++ V W P ++
Sbjct: 319 LGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEV 378
Query: 1025 TGYRLTVGLTRRGQPRQYNVGPS---VSKYPLRNLQPASEYTVSLVAIKGNQE-SPKATG 1080
Y+L G + + V S S+Y + L P +EY +++V ++G E P
Sbjct: 379 DYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLN 438
Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVR--PSQGGEAPREVTSDSGSI 1138
T + +++ VTE T ++W P + K VR + G V D S
Sbjct: 439 GRTEIDSPTNV--VTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDTKEMAVHKDESST 496
Query: 1139 VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
V++GL PG Y + R Q N +T + P NL + + T+SW+
Sbjct: 497 VLTGLKPGEAYKVYVWAERGNQGSKKADTN-ALTEIDSPANLVTDRVTE-NTATISWD-P 553
Query: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
I Y + T + Q+ + E +V +QSS L PG+EY V V+ K D+ES
Sbjct: 554 VQATIDKYVVRYTSADDQE--TREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKK 611
Query: 1259 ISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP 1318
+ P +L + + V+W P + + ++VRY+ E E+ +
Sbjct: 612 ADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAA-IDKYVVRYTSAGGE--TREVPVGK 668
Query: 1319 SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHW 1378
++ VLT L PG EY+V V + ES + +T +DSP + +T N TV W
Sbjct: 669 EQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSW 728
Query: 1379 IAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESP 1438
RATI Y +R+ G RE V ++S LT L PG EY V + A G +ES
Sbjct: 729 DPVRATIDRYVVRYTSAK-DGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESK 787
Query: 1439 LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG 1498
+ T D P++L T + +SWD T+ Y + Y T N +E V
Sbjct: 788 KADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHY--TSANGETREVPVGK 845
Query: 1499 SKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSI 1558
+S+ ++GL+PG++YT+ V+A G + SK +TEID P + V +N
Sbjct: 846 EQSSTVLTGLRPGMEYTVHVWAQKGNQE----SKKADTKAQTEIDGPKNLVTDWVTENMA 901
Query: 1559 SVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPS 1618
+V W P + + Y V T + G T+ G + + + GL+P +EY+V V+AQ +
Sbjct: 902 TVSWDPVQATIDKYMVRYT--SADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGA 959
Query: 1619 GESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFP 1678
ES+ A T +D P+ L + V + W P Q+ Y +TY P+ + E+
Sbjct: 960 QESKKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQFPDGTVKEM-- 1017
Query: 1679 APDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA---IPAPTDLKFTQVTP 1735
E+ LQGL G+ Y VS+VA S+ + T ST P P+D Q
Sbjct: 1018 QLGREDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTLSTVGARFPHPSDCSQVQQNS 1077
Query: 1736 TSLSAQWT 1743
+ S +T
Sbjct: 1078 NAASGLYT 1085
Score = 276 bits (706), Expect = 2e-73
Identities = 242/848 (28%), Positives = 371/848 (43%), Gaps = 60/848 (7%)
Query: 1356 TGLD-----SPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSR 1410
TGLD +P G+ T +S V W P + + Y + ++P ++ +VP +
Sbjct: 255 TGLDCAQVVTPQGLQLLKNTEDSLLVSW-EPSSQVDHYLLSYYPLGKELSGKQIQVPKEQ 313
Query: 1411 NSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
+S + L PGT+Y+V++ + S +T V V T SL + W+
Sbjct: 314 HSYEILGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWEN 373
Query: 1471 PAVTVRYYRITYGETGGNSPVQEFTVPGS---KSTATISGLKPGVDYTITVYAVTGRGDS 1527
P+ V YY++ YG G V E TVP S KS I+GL PG +Y ITV + G
Sbjct: 374 PSTEVDYYKLRYGPMTGQE-VAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGE--- 429
Query: 1528 PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKT 1587
KPI +N RTEID P+ + V +++ +V W P + + Y V T + G TK
Sbjct: 430 -LEGKPILLNGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYT--SADGDTKE 486
Query: 1588 KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDS 1647
D++ + GL+P Y V V+A+ + S+ A+T ID P L V ++
Sbjct: 487 MAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTDRVTENT 546
Query: 1648 IKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE-LQGLRPGSEYTVSVVALH 1706
I+W+ Q + +Y V Y+S +D E G+E ++ L GLRPG EYTV V A
Sbjct: 547 ATISWDPVQATIDKYVVRYTSADD--QETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQK 604
Query: 1707 DDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMK 1766
D ES+ T I +P +L +VT + W P + Y VR T G +
Sbjct: 605 GDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYT--SAGGETR 662
Query: 1767 EINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDAT 1826
E+ + + SS V++GL +Y V V+A K S+ A T ++ P+ T
Sbjct: 663 EVPVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQT--DIDSPQNLVTDRVT 720
Query: 1827 ETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL 1886
E T+SW TI + V A + + + S +TGL+PG +Y ++++
Sbjct: 721 ENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQ 780
Query: 1887 NDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPRE 1946
S A T ID+P NL T N+ VSW P +A I Y++ Y RE
Sbjct: 781 KGAQESKKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETRE 840
Query: 1947 VVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLH 2006
V T +TGL PG EYT++V A K NQ+S KK D Q NL
Sbjct: 841 VPVGKEQSST--VLTGLRPGMEYTVHVWAQKGNQES------KKADTKAQTEIDGPKNLV 892
Query: 2007 GPEILDVPSTVQKTP--------FVTHPGYD-------TGNGIQLPGTSGQQPSVGQQM- 2050
+ + +TV P V + D G +G +P + +
Sbjct: 893 TDWVTENMATVSWDPVQATIDKYMVRYTSADGETREVPVGKEHSSTVLTGLRPGMEYMVH 952
Query: 2051 IFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQT--TISWA-PFQDTSEYIISCH- 2106
++ + G + + T P P N+ A++Q+ ++W P YI++
Sbjct: 953 VWAQKGAQESKKADTKAQTELDP---PRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQF 1009
Query: 2107 PVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEG 2166
P GT +E ++ L GL +GATY + + A K +R + V T ++V
Sbjct: 1010 PDGTVKE---MQLGREDQRFALQGLEQGATYPVSLVAFKGGRRSR---NVSTTLSTVGAR 1063
Query: 2167 LNQPTDDS 2174
P+D S
Sbjct: 1064 FPHPSDCS 1071
Score = 240 bits (612), Expect = 1e-62
Identities = 226/820 (27%), Positives = 353/820 (43%), Gaps = 53/820 (6%)
Query: 636 SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695
S + Y+L + P K+ +P +SY I GL PG T++
Sbjct: 286 SQVDHYLLSYYPLGKELSGKQIQVPKEQHSYEILGLLPG------------------TKY 327
Query: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
T + V+S+ T ++ T+ VT+ T +S V W + S V +++ Y
Sbjct: 328 IVTLRNVKNEVSSSPQHLLATTDLAVLGTA-WVTDETENSLDVEWENPSTEVDYYKLRYG 386
Query: 756 LSEEGDEPQYLDLPSTA---TSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPD 812
G E + +P ++ + +I L PG +Y + V + + E IL +T D
Sbjct: 387 -PMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLNGRTEI-D 444
Query: 813 APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQP 872
+P + D+V + + V W QA I Y + Y+ S +G + E+ + + +S L+ L+P
Sbjct: 445 SPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYT-SADGDTKEMAVHKDESSTVLTGLKP 503
Query: 873 GVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES 932
G Y + ++A NQ S + T + SP +L VT+ TI W P ++
Sbjct: 504 GEAYKVYVWAERGNQGS-------KKADTNALTEIDSPANLVTDRVTENTATISWDPVQA 556
Query: 933 AVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ 992
+ Y V + E + L + +TGL PGV Y V+A RESK
Sbjct: 557 TIDKYVVRYTSAD-DQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKKADTN 615
Query: 993 QTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYP 1052
T +D+P NL T++ V W P +A I Y + + G+ R+ VG S
Sbjct: 616 APTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRY-TSAGGETREVPVGKEQSSTV 674
Query: 1053 LRNLQPASEYTVSLVAIKGNQESPKA-TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
L L+P EY V + A KG+QES KA T T + ++ VTE ++W P
Sbjct: 675 LTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNL--VTDRVTENMATVSWDPVR 732
Query: 1112 RIGFKLGVR--PSQGGEAPREVT--SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167
+ VR ++ GE REV + S V++GL PGVEY + + QE
Sbjct: 733 ATIDRYVVRYTSAKDGET-REVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQE-SKKAD 790
Query: 1168 NKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
K T + P NL + + TVSW+ I Y + T NG+ + E V
Sbjct: 791 TKAQTDIDSPQNLVTDWVTE-NTATVSWD-PVQATIDRYVVHYTSANGE---TREVPVGK 845
Query: 1228 DQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTW 1287
+QSS L PG+EY V V+ K ++ES + P +L + + V+W
Sbjct: 846 EQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATVSW 905
Query: 1288 APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHES 1347
P + ++VRY+ E E+ + ++ VLT L PG EY+V V + ES
Sbjct: 906 -DPVQATIDKYMVRYTSADGE--TREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQES 962
Query: 1348 TPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP 1407
+ +T LD P + S +T + + W P A I GY + + + G +E ++
Sbjct: 963 KKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTY--QFPDGTVKEMQLG 1020
Query: 1408 HSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV 1447
L L G Y VS+VA G S + STV
Sbjct: 1021 REDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTLSTV 1060
Score = 223 bits (567), Expect = 2e-57
Identities = 210/764 (27%), Positives = 332/764 (43%), Gaps = 55/764 (7%)
Query: 619 TPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNS---YTIKGLKPGV 675
T NS ++W P + + Y LR+ P E T+P + Y I GL PG
Sbjct: 360 TDETENSLDVEWENPS-TEVDYYKLRYGPMTGQ-EVAEVTVPKSSDPKSRYDITGLHPGT 417
Query: 676 VYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASS 735
Y+ ++ ++ G E P+ N G T SP ++ VTE TA+
Sbjct: 418 EYKITVVPMR--GELE-----------GKPILLN---GRTEIDSPTNVVTDRVTEDTAT- 460
Query: 736 FVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISE 795
VSW + + V Y S +GD + + + +S + L PG Y VY +E
Sbjct: 461 --VSWDPVQAVIDKYVVRYT-SADGDTKE-MAVHKDESSTVLTGLKPGEAY--KVYVWAE 514
Query: 796 DGEQ-SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSST 854
G Q S T+ T D+P + D+V + + + W QA I Y + Y+ + + +
Sbjct: 515 RGNQGSKKADTNALTEIDSPANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETR 574
Query: 855 ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQ 914
E+ + + +S L+ L+PGV+Y + ++A + ++ES ++ T P + SP++L
Sbjct: 575 EVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRES-----KKADTNAPTD--IDSPKNLV 627
Query: 915 FVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEV-TGLSPGVTY 973
VT+ T+ W P ++A+ Y V+ G + +P+ + + V TGL PG+ Y
Sbjct: 628 TDRVTENMATVSWDPVQAAIDKY---VVRYTSAGGETREVPVGKEQSSTVLTGLRPGMEY 684
Query: 974 YFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGL 1033
V+A +ESK + T +D+P NL T++ V W P RA I Y +
Sbjct: 685 MVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSWDPVRATIDRYVVRYTS 744
Query: 1034 TRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKA-TGVFTTLQPGSSIP 1092
+ G+ R+ VG S L L+P EYTV + A KG QES KA T T + ++
Sbjct: 745 AKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTKAQTDIDSPQNL- 803
Query: 1093 PYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVT--SDSGSIVVSGLTPGVEYV 1150
VTE T ++W P + V + REV + S V++GL PG+EY
Sbjct: 804 -VTDWVTENTATVSWDPVQATIDRYVVHYTSANGETREVPVGKEQSSTVLTGLRPGMEYT 862
Query: 1151 YTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITT 1210
+ + QE K T + P NL + + + TVSW+ I Y +
Sbjct: 863 VHVWAQKGNQE-SKKADTKAQTEIDGPKNLVTDWVTE-NMATVSWD-PVQATIDKYMVRY 919
Query: 1211 TPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPP 1270
T +G+ + E V + SS L PG+EY V V+ K +ES + PP
Sbjct: 920 TSADGE---TREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKADTKAQTELDPP 976
Query: 1271 TDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLP 1330
+LR + + +TW PPS + +++ Y + V E+ + D L L
Sbjct: 977 RNLRPSAVTQSGGILTWT-PPSAQIHGYILTYQ--FPDGTVKEMQLGREDQRFALQGLEQ 1033
Query: 1331 GTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANS 1373
G Y VS+ + S + T G P D S + NS
Sbjct: 1034 GATYPVSLVAFKGGRRSRNVSTTLSTVGARFPHPSDCSQVQQNS 1077
Score = 157 bits (398), Expect = 9e-38
Identities = 145/579 (25%), Positives = 246/579 (42%), Gaps = 41/579 (7%)
Query: 1635 PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRP 1694
P+GL DS+ ++WE P QV Y ++Y + E+ + E+ GL P
Sbjct: 265 PQGLQLLKNTEDSLLVSWE-PSSQVDHYLLSYYPLGKELSGKQIQVPKEQHSYEILGLLP 323
Query: 1695 GSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRV 1754
G++Y V++ + +++ S P +T + T T SL +W P+ ++ Y++
Sbjct: 324 GTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEVDYYKL 383
Query: 1755 RVTPKEKTGP-MKEINLAPDS---SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTT 1810
R P TG + E+ + S S ++GL T+Y+++V ++ L +P ++
Sbjct: 384 RYGPM--TGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPI--LLNG 439
Query: 1811 LENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTI 1870
+ P TE T T+SW I + V A+G T + + D S +
Sbjct: 440 RTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDTK-EMAVHKDESSTVL 498
Query: 1871 TGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARI 1930
TGL+PG YK+Y++ N S +A T ID+P+NL T N+ +SW P +A I
Sbjct: 499 TGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTDRVTENTATISWDPVQATI 558
Query: 1931 TGYIIKYEKPGSPP-REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRK 1989
Y+++Y REV+ T +TGL PG EYT++V A K +++S +K
Sbjct: 559 DKYVVRYTSADDQETREVLVGKEQSST--VLTGLRPGVEYTVHVWAQKGDRES-----KK 611
Query: 1990 KTDELPQLVTLPHPNLHGPEILDVPSTVQKTP-------FVTHPGYDTGNGIQLPGTSGQ 2042
P + P NL + + +TV P +V G ++P Q
Sbjct: 612 ADTNAPTDIDSPK-NLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGETREVPVGKEQ 670
Query: 2043 QPSV------GQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQT--TISWAP 2094
+V G + + + A P N+ + +++ T+SW P
Sbjct: 671 SSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSWDP 730
Query: 2095 FQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRH---- 2150
+ T + + + D E + V +S LTGL G Y + V A K Q
Sbjct: 731 VRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKAD 790
Query: 2151 -KVREEVVTVGNSVNEGLNQPTDDSCFDPY--TVSHYAV 2186
K + ++ + N V + + + T +DP T+ Y V
Sbjct: 791 TKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVV 829
Score = 84.7 bits (208), Expect = 1e-15
Identities = 100/413 (24%), Positives = 170/413 (41%), Gaps = 51/413 (12%)
Query: 1814 VSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQ-TPIQRTIKPDVRSYTITG 1872
V P+ ++ TE ++ +SW ++ + + + P + + Q + + SY I G
Sbjct: 262 VVTPQGLQLLKNTEDSLLVSWEPSSQ-VDHYLLSYYPLGKELSGKQIQVPKEQHSYEILG 320
Query: 1873 LQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITG 1932
L PGT Y + L + + SSP + A+T + T NSL V W+ P +
Sbjct: 321 LLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEVDY 380
Query: 1933 YIIKY-EKPGSPPREV-VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLI--GR 1988
Y ++Y G EV VP+ + ITGL PGTEY I V+ ++ + +P++ GR
Sbjct: 381 YKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLNGR 440
Query: 1989 KKTDELPQLVTLPHPNLHGPEILDVPSTVQKTP-----------FVTHPGYDTGNGIQLP 2037
+ D +VT + + +TV P + + G +
Sbjct: 441 TEIDSPTNVVT--------DRVTEDTATVSWDPVQAVIDKYVVRYTSADGDTKEMAVHKD 492
Query: 2038 GTS----GQQPSVGQQM-IFEEHGFRRTTPPTT--ATPIRHRPRPYPPNVGQEALSQTT- 2089
+S G +P ++ ++ E G + + T T I P N+ + +++ T
Sbjct: 493 ESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDS-----PANLVTDRVTENTA 547
Query: 2090 -ISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALK-DQ 2147
ISW P Q T + + + D+E + V +S LTGL G Y + V A K D+
Sbjct: 548 TISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDR 607
Query: 2148 QRHKVREEVVT--------VGNSVNEGLNQPTDD---SCFDPYTVSHYAVGDE 2189
+ K T V + V E + + D + D Y V + + G E
Sbjct: 608 ESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGE 660
>gi|93141049 collagen, type XII, alpha 1 short isoform precursor [Homo
sapiens]
Length = 1899
Score = 296 bits (757), Expect = 2e-79
Identities = 244/929 (26%), Positives = 413/929 (44%), Gaps = 43/929 (4%)
Query: 997 LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNL 1056
L+AP+NL T + V WTPP + Y++ G+ +++ V + L++L
Sbjct: 221 LEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDL 280
Query: 1057 QPASEYTVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTP-APRIG 1114
+P +EY V++ ++ ++ S G TL P S+ Y +V TT+ + W P G
Sbjct: 281 KPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIY--DVGPTTMHVQWQPVGGATG 338
Query: 1115 FKLGVRPSQGGEAPREVTSDSGSIV----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
+ L +P + E R G V ++ L P EY T+Q + + V +V
Sbjct: 339 YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREV 398
Query: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230
PL P +L L + + V WE P I T + +E V ++
Sbjct: 399 TLPLPRPQDLKLR-DVTHSTMNVFWE--PVPGKVRKYIVRYKTPEEDVKEVE--VDRSET 453
Query: 1231 SCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDTMRVTWA 1288
S + +L Y VSV V D+ ES P++ +T P VP PT+L+ T + + R TW
Sbjct: 454 STSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRP-VPAPTNLKITEVTSEGFRGTWD 512
Query: 1289 PPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHES 1347
S D++ + + ++P D E ++ +N +V NL P T Y VS++++Y ++ ES
Sbjct: 513 HGAS-DVSLYRITWAPF-GSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESES 570
Query: 1348 TPLRGRQKT--------GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSG 1399
L G ++T P + + T+NS TV W + YRI + P G
Sbjct: 571 DDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEG 630
Query: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVA 1458
+ + +NS+ L L P T Y +++ +L E + G+ T + R+L V
Sbjct: 631 NEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYD 690
Query: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
+ ++L + WD R Y++ Y G P + +PG+ + A + L+P YT+TV
Sbjct: 691 PSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTVTV 749
Query: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTP 1578
V GD +S R +QV + NS+ V+W P+ PV YRV +P
Sbjct: 750 VPVYTEGDGGRTSDTGRTLMR---GLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSP 806
Query: 1579 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTNIDRPKG 1637
+G P+++ + + +E L P Y V++ A GE P Q P+
Sbjct: 807 VDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRN 866
Query: 1638 LAFTDVDVDSIKIAWESPQGQVSRYRVTYS-SPEDGIHELFPAPDGEEDTAELQGLRPGS 1696
L +S+ +AW+ G V +YR+ YS + D I E P G + LQ L+P +
Sbjct: 867 LRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVP-GRRNNVILQPLQPDT 925
Query: 1697 EYTVSVVALHDDMESQPLIGT-QSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR 1755
Y ++V+A+++D + L G ++ + P ++ + T W P + GY++
Sbjct: 926 PYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIV 985
Query: 1756 VTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLE-NV 1814
P PM+ + +S + L +T Y+V+VYA D+ S P TTL NV
Sbjct: 986 YKPVGSNEPMEA--FVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNV 1043
Query: 1815 SPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ 1874
+ + ++ T + W + T +++ PA+G + T++ S+ TGL
Sbjct: 1044 TDLKTYQI---GWDTFCVKW-SPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLS 1099
Query: 1875 PGTDYKIYLYTLNDNARSSPVVIDASTAI 1903
P TDY + ++ N V + T +
Sbjct: 1100 PDTDYGVTVFVQTPNLEGPGVSVKEHTTV 1128
Score = 286 bits (732), Expect = 2e-76
Identities = 233/843 (27%), Positives = 380/843 (45%), Gaps = 32/843 (3%)
Query: 1166 IVNKVVTP--LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223
+ N V P L P+NL + VSW + + Y++ P +G G E
Sbjct: 211 LCNSVKGPGDLEAPSNLVISERTHRS-FRVSWT-PPSDSVDRYKVEYYPVSG--GKRQEF 266
Query: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTM 1283
V ++S +L P EY V+VY+V +D+ S P+ T P L ++GP TM
Sbjct: 267 YVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTM 326
Query: 1284 RVTWAPPPSIDLTNFLVRYSPVKNEEDVA--ELSISPSDNAVVLTNLLPGTEYVVSVSSV 1341
V W P T +++ Y PVK+ E E+ + P+ N + LT+L+P TEY V+V +V
Sbjct: 327 HVQWQPVGGA--TGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAV 384
Query: 1342 YEQHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH-PEHFSG 1399
S P+ R+ T L P + D+T ++ V W + Y +R+ PE
Sbjct: 385 LHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEE--- 441
Query: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVA 1458
+E V S S +L +L T Y VS+ A++ ESP + Q++T P +L++
Sbjct: 442 DVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITE 501
Query: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
T +WD A V YRIT+ G +S E + G ++T L P Y +++
Sbjct: 502 VTSEGFRGTWDHGASDVSLYRITWAPFG-SSDKMETILNGDENTLVFENLNPNTIYEVSI 560
Query: 1519 YAV----TGRGDSPASSKPISINYRTEIDK--PSQMQVTDVQDNSISVKWLPSSSPVTGY 1572
A+ + D S + + I T+ K P +QV + NS++VKW P+S V Y
Sbjct: 561 TAIYPDESESDDLIGSERTLPI-LTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKY 619
Query: 1573 RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN- 1631
R+T P G G +T T G Q + ++ L+P Y ++V + P GE + T
Sbjct: 620 RITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKP 679
Query: 1632 IDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQG 1691
++ + L D ++ + W+ +G +Y++ Y+ G EL P P G + A L+
Sbjct: 680 LNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIP-GNTNYAILRN 738
Query: 1692 LRPGSEYTVSVVALHDDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNVQLT 1750
L+P + YTV+VV ++ + + T T + +++ TP SL +W P +
Sbjct: 739 LQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVL 798
Query: 1751 GYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTT 1810
YRV +P + T P + I + ++ V + L+ T Y V++ AL P+ T
Sbjct: 799 QYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRT 858
Query: 1811 LENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTI 1870
L S PR RV T +++++W + +++ P G + T P R+ I
Sbjct: 859 LPR-SGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVI 917
Query: 1871 -TGLQPGTDYKIYLYTLNDNARSSPVVIDAST-AIDAPSNLRFLATTPNSLLVSWQPPRA 1928
LQP T YKI + + ++ + + T + P N+ VSW P +
Sbjct: 918 LQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPS 977
Query: 1929 RITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGR 1988
+ GY I Y+ GS E + +T T+ L P T Y + V A ++ S PL +
Sbjct: 978 PVLGYKIVYKPVGS--NEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQ 1035
Query: 1989 KKT 1991
T
Sbjct: 1036 GTT 1038
Score = 278 bits (711), Expect = 5e-74
Identities = 244/917 (26%), Positives = 395/917 (43%), Gaps = 53/917 (5%)
Query: 728 VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYI 787
++E T SF VSW SD+V ++VEY G + Q + TS + DL P +Y+
Sbjct: 229 ISERTHRSFRVSWTPPSDSVDRYKVEY-YPVSGGKRQEFYVSRMETSTVLKDLKPETEYV 287
Query: 788 VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSP 847
VNVY + ED E S L ++ T P + V T++ V+W +P TGY + Y P
Sbjct: 288 VNVYSVVED-EYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQW-QPVGGATGYILSYKP 345
Query: 848 SVEGSST---ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
+ T E+ L T N + L+DL P +Y +T+ AV + S PV +++ T PR
Sbjct: 346 VKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPR- 404
Query: 905 DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRN-TFAE 963
P+DL+ +VT + + W P V Y ++ P E + + + R+ T
Sbjct: 405 -----PQDLKLRDVTHSTMNVFWEPVPGKVRKY---IVRYKTPEEDVKEVEVDRSETSTS 456
Query: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRA 1022
+ L Y V AV ES P+TAQ+TT+ + APTNL+ T W +
Sbjct: 457 LKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGAS 516
Query: 1023 QITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQE-------S 1075
++ YR+T + + + NL P + Y VS+ AI ++ S
Sbjct: 517 DVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 576
Query: 1076 PKATGVFTTLQPGSSIPPYNTEV---TETTIVITWTPAP-RI-GFKLGVRPS--QGGEAP 1128
+ + TT P S P N +V T ++ + W PA R+ +++ +PS +G E
Sbjct: 577 ERTLPILTTQAPKSG--PRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQT 634
Query: 1129 REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
+ S+V+ L P Y T+ L E PL+ NL + +P T
Sbjct: 635 TTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRV-YDPST 693
Query: 1189 GVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVS-- 1246
L V W+ + + Y++ P G G + + + NL P Y V+
Sbjct: 694 STLNVRWDHA-EGNPRQYKLFYAPAAG--GPEELVPIPGNTNYAILRNLQPDTSYTVTVV 750
Query: 1247 -VYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPV 1305
VYT D + T++ + +++ N P+++ V W P P + + V YSPV
Sbjct: 751 PVYTEGDGGRTSDTGRTLMRGL--ARNVQVYNPTPNSLDVRWDPAPG-PVLQYRVVYSPV 807
Query: 1306 KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGI 1364
+ + + V L L+P T Y V++ ++Y E P + +T P +
Sbjct: 808 DGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNL 867
Query: 1365 DFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEY 1424
T NS +V W + YRI + P VP RN++ L L P T Y
Sbjct: 868 RVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPY 927
Query: 1425 VVSIVALNGREESPLLIGQQSTVSDV-PRDLEVVAATPTSLLISWDAPAVTVRYYRITYG 1483
++++A+ + L G TV + P+++ + T +SWD V Y+I Y
Sbjct: 928 KITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYK 987
Query: 1484 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
G N P++ F G ++ T+ L P Y + VYA G S P++ T
Sbjct: 988 PVGSNEPMEAFV--GEMTSYTLHNLNPSTTYDVNVYAQYDSG----LSVPLTDQGTTLYL 1041
Query: 1544 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
+ ++ + ++ VKW P + T YR+ +P +G + G +T GL
Sbjct: 1042 NVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKLSPADGTRGQEITVRG-SETSHCFTGLS 1099
Query: 1604 PTVEYVVSVYAQNPSGE 1620
P +Y V+V+ Q P+ E
Sbjct: 1100 PDTDYGVTVFVQTPNLE 1116
Score = 276 bits (705), Expect = 2e-73
Identities = 253/942 (26%), Positives = 416/942 (44%), Gaps = 62/942 (6%)
Query: 1087 PGSSIPPYNTEVTETT---IVITWTPAPRI--GFKLGVRPSQGGEAPR-EVTSDSGSIVV 1140
PG P N ++E T ++WTP +K+ P GG+ V+ S V+
Sbjct: 218 PGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVL 277
Query: 1141 SGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199
L P EYV + V+ D E P+ T P +L++ D G T+ +
Sbjct: 278 KDLKPETEYVVNVYSVVED--EYSEPLKGTEKTLPVPVVSLNIY---DVGPTTMHVQWQP 332
Query: 1200 TPDITGYRITTTPTNGQQGNSLEEV-VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
TGY ++ P + +EV + + +L P EY V+V V D S P
Sbjct: 333 VGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEP 392
Query: 1259 IS--DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316
++ + +P +P P DL+ ++ TM V W P P + ++VRY EEDV E+ +
Sbjct: 393 VTVREVTLP-LPRPQDLKLRDVTHSTMNVFWEPVPG-KVRKYIVRYKTP--EEDVKEVEV 448
Query: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITANSFT 1375
S+ + L +L T Y VSVS+V+++ ES P+ ++ T + +PT + +++T+ F
Sbjct: 449 DRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFR 508
Query: 1376 VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGRE 1435
W + ++ YRI P S + E + N++ NL P T Y VSI A+ E
Sbjct: 509 GTWDHGASDVSLYRITWAPFGSSDK-METILNGDENTLVFENLNPNTIYEVSITAIYPDE 567
Query: 1436 -ESPLLIGQQSTVSDV--------PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETG 1486
ES LIG + T+ + PR+L+V AT SL + WD + V+ YRITY +
Sbjct: 568 SESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPST 627
Query: 1487 GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT-----GRGDSPASSKPISINYRTE 1541
G Q T+ G +++ + LKP YTITV ++ GR +KP++
Sbjct: 628 GEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNT----- 682
Query: 1542 IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG 1601
++V D ++++V+W + Y++ P G GP + + +
Sbjct: 683 ---VRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRN 738
Query: 1602 LQPTVEY---VVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQ 1658
LQP Y VV VY + G + +T + + R + + +S+ + W+ G
Sbjct: 739 LQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR--NVQVYNPTPNSLDVRWDPAPGP 796
Query: 1659 VSRYRVTYSSPEDGIH--ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIG 1716
V +YRV YS P DG E P G L+ L P + Y+V++VAL+ D E P
Sbjct: 797 VLQYRVVYS-PVDGTRPSESIVVP-GNTRMVHLERLIPDTLYSVNLVALYSDGEGNPS-P 853
Query: 1717 TQSTAIP--APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS 1774
Q +P P +L+ T SLS W + + YR+ +P P+ E P
Sbjct: 854 AQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGR 912
Query: 1775 -SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITIS 1833
++V++ L T Y+++V A+ + G T+ + PP+ ++D T +S
Sbjct: 913 RNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV-GLLPPQNIHISDEWYTRFRVS 971
Query: 1834 WRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSS 1893
W + G+++ P P++ + ++ SYT+ L P T Y + +Y D+ S
Sbjct: 972 WDPSPSPVLGYKIVYKPVGSNEPMEAFVG-EMTSYTLHNLNPSTTYDVNVYAQYDSGLSV 1030
Query: 1894 PVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRP 1953
P+ +T ++L+ ++ V W P RA T Y +K P R R
Sbjct: 1031 PLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKL-SPADGTRGQEITVRG 1088
Query: 1954 GVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP 1995
T TGL P T+Y + V N + + ++ T P
Sbjct: 1089 SETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKP 1130
Score = 256 bits (655), Expect = 1e-67
Identities = 254/947 (26%), Positives = 393/947 (41%), Gaps = 51/947 (5%)
Query: 812 DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ 871
+AP + + + S V W+ P + Y++ Y P G E + S L DL+
Sbjct: 222 EAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLK 281
Query: 872 PGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE 931
P +Y + +Y+V E++ S P+ GT ++ VP L +V + + W P
Sbjct: 282 PETEYVVNVYSVVEDEYSEPL------KGTEKTLPVPVV-SLNIYDVGPTTMHVQWQPVG 334
Query: 932 SAVTGYRVDVIPV-----NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
A TGY + PV P E RL + N ++T L P Y V AV H S
Sbjct: 335 GA-TGYILSYKPVKDTEPTRPKE--VRLGPTVNDM-QLTDLVPNTEYAVTVQAVLHDLTS 390
Query: 987 KPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVG 1045
+P+T ++ T L P +L+ + T ST+ V W P ++ Y + T ++ V
Sbjct: 391 EPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKY-IVRYKTPEEDVKEVEVD 449
Query: 1046 PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105
S + L++L + YTVS+ A+ ESP T TT + TEVT
Sbjct: 450 RSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRG 509
Query: 1106 TWTPAPRIGFKLGVRPSQGGEAPREVT---SDSGSIVVSGLTPGVEYVYTIQVLRD---- 1158
TW + + G + + T D ++V L P Y +I +
Sbjct: 510 TWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESE 569
Query: 1159 -----GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT 1213
G ER PI+ P S P NL + N + LTV W+ + + YRIT P+
Sbjct: 570 SDDLIGSERTLPILT-TQAPKSGPRNLQV-YNATSNSLTVKWD-PASGRVQKYRITYQPS 626
Query: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDT-IIPAVPPPTD 1272
G +GN + Q+S L P Y ++V ++ D E ++ + +
Sbjct: 627 TG-EGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRN 685
Query: 1273 LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332
LR + T+ V W + + + Y+P + + I + N +L NL P T
Sbjct: 686 LRVYDPSTSTLNVRWDHAEG-NPRQYKLFYAPAAGGPEEL-VPIPGNTNYAILRNLQPDT 743
Query: 1333 EYVVSVSSVYEQHESTPLRGRQKTGLDS-PTGIDFSDITANSFTVHWIAPRATITGYRIR 1391
Y V+V VY + + +T + + + T NS V W + YR+
Sbjct: 744 SYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVV 803
Query: 1392 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSDV 1450
+ P + VP + + L L P T Y V++VAL + E +P ++
Sbjct: 804 YSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSG 863
Query: 1451 PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEF-TVPGSKSTATISGLK 1509
PR+L V T SL ++WD V+ YRI Y T G+ P+ E+ TVPG ++ + L+
Sbjct: 864 PRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGRRNNVILQPLQ 922
Query: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRT-EIDKPSQMQVTDVQDNSISVKWLPSSSP 1568
P Y ITV AV GD ++ N RT + P + ++D V W PS SP
Sbjct: 923 PDTPYKITVIAVYEDGD----GGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSP 978
Query: 1569 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628
V GY++ P P + + T T+ L P+ Y V+VYAQ SG S PL
Sbjct: 979 VLGYKIVYKPVGSNEPMEAFVG--EMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQG 1036
Query: 1629 VTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE 1688
T L + D+ + W SP + YR+ SP DG G E +
Sbjct: 1037 TTLYLNVTDLKTYQIGWDTFCVKW-SPHRAATSYRLKL-SPADGTRGQEITVRGSETSHC 1094
Query: 1689 LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTP 1735
GL P ++Y V+V ++E P + + PT+ TP
Sbjct: 1095 FTGLSPDTDYGVTVFVQTPNLEG-PGVSVKEHTTVKPTEAPTEPPTP 1140
Score = 200 bits (508), Expect = 2e-50
Identities = 217/866 (25%), Positives = 356/866 (41%), Gaps = 75/866 (8%)
Query: 623 PNSHPIQWNAPQP-SHISKYILRWRPKNSVG--RWKEATIPGHLNSYTIKGLKPGVVYEG 679
P + +QW QP + YIL ++P R KE + +N + L P Y
Sbjct: 323 PTTMHVQW---QPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYA- 378
Query: 680 QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE-SVTEITASSFVV 738
+++Q H TS PVT VT PL + + ++T S+ V
Sbjct: 379 --VTVQAVLHD----------LTSEPVTVREVT------LPLPRPQDLKLRDVTHSTMNV 420
Query: 739 SWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798
W V + V Y+ EE + +D T+TS+ DL Y V+V + ++GE
Sbjct: 421 FWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLK--DLFSQTLYTVSVSAVHDEGE 478
Query: 799 QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858
+ + T AP + + +V W + ++ YRI ++P E L
Sbjct: 479 SPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETIL 538
Query: 859 PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE------TTGTPRSDTVPSPRD 912
N++ +L P Y ++I A+ ++ + +I E TT P+S PR+
Sbjct: 539 NGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKS----GPRN 594
Query: 913 LQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVT 972
LQ T +T+ W P V YR+ P G R + L P
Sbjct: 595 LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 654
Query: 973 YYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031
Y V ++ E +T + TK L+ NL+ + + ST+ VRW Y+L
Sbjct: 655 YTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFY 714
Query: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG--S 1089
G + + + LRNLQP + YTV++V + + + + TL G
Sbjct: 715 APAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR 774
Query: 1090 SIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSG------- 1142
++ YN T ++ + W PAP + V S P + T S SIVV G
Sbjct: 775 NVQVYNP--TPNSLDVRWDPAPGPVLQYRVVYS-----PVDGTRPSESIVVPGNTRMVHL 827
Query: 1143 --LTPGVEY-VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199
L P Y V + + DG+ +P + + P S P NL + T L+V+W+ +
Sbjct: 828 ERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL-PRSGPRNLRV-FGETTNSLSVAWDHAD 885
Query: 1200 TPDITGYRITTTPTNGQQGNSLEE--VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257
P + YRI +PT G+ ++E V +++ L P Y ++V V +D +
Sbjct: 886 GP-VQQYRIIYSPT---VGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGG 941
Query: 1258 PIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316
++ + + PP ++ ++ RV+W P PS + + + Y PV + E + +
Sbjct: 942 HLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPS-PVLGYKIVYKPVGSNEPME--AF 998
Query: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTV 1376
+ L NL P T Y V+V + Y+ S PL + T + T + I ++F V
Sbjct: 999 VGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCV 1058
Query: 1377 HWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436
W +P T YR++ P R +E V S S T L+P T+Y V++ E
Sbjct: 1059 KW-SPHRAATSYRLKLSPAD-GTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLE 1116
Query: 1437 SP-LLIGQQSTVSDVPRDLEVVAATP 1461
P + + + +TV P + TP
Sbjct: 1117 GPGVSVKEHTTVK--PTEAPTEPPTP 1140
Score = 155 bits (391), Expect = 6e-37
Identities = 153/655 (23%), Positives = 255/655 (38%), Gaps = 48/655 (7%)
Query: 636 SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695
S +S Y + W P S + E + G N+ + L P +YE +SI E
Sbjct: 516 SDVSLYRITWAPFGSSDKM-ETILNGDENTLVFENLNPNTIYE---VSITAIYPDESESD 571
Query: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
D + + P+ TT + V T++S V W AS V +R+ Y+
Sbjct: 572 DLIGSERTLPIL-------TTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQ 624
Query: 756 LSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP 815
S Q + SV + L P Y + V + DGE + +T +
Sbjct: 625 PSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVR 684
Query: 816 DPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQ 875
+ V +++ VRW + Y++ Y+P+ G + +P N L +LQP
Sbjct: 685 NLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTS 744
Query: 876 YNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVT 935
Y +T+ V + T+ T R+ R++Q T + + W P V
Sbjct: 745 YTVTVVPVYTEGDG------GRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVL 798
Query: 936 GYRVDVIPVNLPGEHGQRLPISRNT-FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ-Q 993
YRV PV+ + + + NT + L P Y + A+ E P AQ +
Sbjct: 799 QYRVVYSPVD-GTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGR 857
Query: 994 TTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS-VSKYP 1052
T P NL+ ET +++ V W + YR+ T +Y P +
Sbjct: 858 TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVI 917
Query: 1053 LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTE---TTIVITW-- 1107
L+ LQP + Y ++++A+ + + TG T+ +PP N +++ T ++W
Sbjct: 918 LQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV---GLLPPQNIHISDEWYTRFRVSWDP 974
Query: 1108 TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167
+P+P +G+K+ +P E + S + L P Y + D P+
Sbjct: 975 SPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYD-SGLSVPLT 1033
Query: 1168 NKVVTPLSPPTNLH-LEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVH 1226
++ T T+L + DT V W S T YR+ +P +G +G E V
Sbjct: 1034 DQGTTLYLNVTDLKTYQIGWDT--FCVKW--SPHRAATSYRLKLSPADGTRGQ--EITVR 1087
Query: 1227 ADQSSCTFDNLSPGLEYNVSVY-----------TVKDDKESVPISDTIIPAVPPP 1270
++S F LSP +Y V+V+ +VK+ P P PPP
Sbjct: 1088 GSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPP 1142
Score = 76.6 bits (187), Expect = 3e-13
Identities = 84/359 (23%), Positives = 144/359 (40%), Gaps = 55/359 (15%)
Query: 1813 NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITG 1872
++ P +++ T + +SW ++++ ++V+ P +G + + S +
Sbjct: 220 DLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKD 279
Query: 1873 LQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITG 1932
L+P T+Y + +Y++ ++ S P+ T +L P ++ V WQP TG
Sbjct: 280 LKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGA-TG 338
Query: 1933 YIIKYE--KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKK 1990
YI+ Y+ K P R R P V + +T L P TEY + V A+ ++ SEP+ R+
Sbjct: 339 YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVRE- 397
Query: 1991 TDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPG--------YDT-GNGIQLPGTSG 2041
VTLP P ++ DV + + PG Y T ++
Sbjct: 398 -------VTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDR 450
Query: 2042 QQPSVGQQMIFEEHGF---------RRTTPPTTATPIRHRPRPYPPNV------------ 2080
+ S + +F + + +PP TA RP P P N+
Sbjct: 451 SETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETT-RPVPAPTNLKITEVTSEGFRG 509
Query: 2081 ----GQEALSQTTISWAPF--QDTSEYIISCHPVGTDEEPLQFR--VPGTSTSATLTGL 2131
G +S I+WAPF D E I++ DE L F P T ++T +
Sbjct: 510 TWDHGASDVSLYRITWAPFGSSDKMETILN-----GDENTLVFENLNPNTIYEVSITAI 563
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 235 bits (599), Expect = 4e-61
Identities = 229/852 (26%), Positives = 364/852 (42%), Gaps = 59/852 (6%)
Query: 902 PRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN-----LPGEHGQRLPI 956
P D+ +PRDL E + + + WT VTGY+V P+ LP E +
Sbjct: 227 PPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQEVNVP 286
Query: 957 SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ-QTTKLDAPTNLQFVNETDSTVLV 1015
+ T + GL P Y V A+ + ++ +TT L+ P L N T ++LV
Sbjct: 287 AGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGP-ELTIQNTTAHSLLV 345
Query: 1016 RW-TPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQE 1074
W + P A TGYR+T + G +Q +GP LR+L+P ++Y V++ + G
Sbjct: 346 AWRSVPGA--TGYRVTWRVLSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTLFGRSV 403
Query: 1075 SPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI-GFKLGVRPSQGGEAPREVT- 1132
P AT + + T+I+++W P G++L R G E P++V
Sbjct: 404 GP-ATSLMARTDASVEQTLRPVILGPTSILLSWNLVPEARGYRLEWRRETGLEPPQKVVL 462
Query: 1133 -SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAP---IVNKVVTPLSPPTNLHLEANPDT 1188
SD + GL PG EY T+ L +G E P + P+SP T+L P
Sbjct: 463 PSDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPVSPVTDLQATELPGQ 522
Query: 1189 GVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVY 1248
V VSW S P T YRI T G + V+ Q++ D++ GL Y V V
Sbjct: 523 RV-RVSW--SPVPGATQYRIIVRSTQGVERTL---VLPGSQTAFDLDDVQAGLSYTVRVS 576
Query: 1249 TVKDDKESVPISDTIIPAVPPPT---DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPV 1305
+E T+ P LR +RV W P P + F + +S
Sbjct: 577 ARVGPREGSASVLTVRREPETPLAVPGLRVVVSDATRVRVAWGPVPGA--SGFRISWSTG 634
Query: 1306 KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG-I 1364
E + ++ P A +T L PGT Y V+VS + + E +T P +
Sbjct: 635 SGPE--SSQTLPPDSTATDITGLQPGTTYQVAVSVLRGREEGPAAVIVARTDPLGPVRTV 692
Query: 1365 DFSDITANSFTVHWI-APRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423
+ +++S T+ W P AT GYR+ H H G + V L L P TE
Sbjct: 693 HVTQASSSSVTITWTRVPGAT--GYRVSWHSAH--GPEKSQLVSGEATVAELDGLEPDTE 748
Query: 1424 YVVSIVA----LNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYR 1479
Y V + A ++G S ++ V V R L+++ A+ L I+W YR
Sbjct: 749 YTVHVRAHVAGVDGPPASVVVRTAPEPVGRVSR-LQILNASSDVLRITW-VGVTGATAYR 806
Query: 1480 ITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
+ +G + G P++ +PG+ +A I GL+ GV Y++ V A+ G + P+SI
Sbjct: 807 LAWGRSEGG-PMRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGT----PVSIVVT 861
Query: 1540 TEIDKP---SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1596
T + P + V ++S+ ++W P G+ + P+ G +++ GP+ +
Sbjct: 862 TPPEAPPALGTLHVVQRGEHSLRLRWEPVPR-AQGFLLHWQPEGGQ--EQSRVLGPELSS 918
Query: 1597 MTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKG--LAFTDVDVDSIKIAWES 1654
++GL+P +Y V + P+GE TA T R L D +DS+ +AW +
Sbjct: 919 YHLDGLEPATQYRVRLSVLGPAGEGPSAEVTARTESPRVPSIELRVVDTSIDSVTLAW-T 977
Query: 1655 PQGQVSRYRVTYSSPEDGIHELFPAPD---GEEDTAELQGLRPGSEYTVSVVALHDDMES 1711
P + S Y +++ E+ +P G + + GL PG Y S+ + D +
Sbjct: 978 PVSRASSYILSWRPLRGPGQEVPGSPQTLPGISSSQRVTGLEPGVSYIFSLTPVLDGVRG 1037
Query: 1712 QPLIGTQSTAIP 1723
TQ+ P
Sbjct: 1038 PEASVTQTPVCP 1049
Score = 202 bits (515), Expect = 2e-51
Identities = 207/821 (25%), Positives = 342/821 (41%), Gaps = 73/821 (8%)
Query: 1360 SPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRP-----REDRVPHSRNSIT 1414
+P + S+ ++ S V W A +TGY++++ P G+P +E VP S+
Sbjct: 234 APRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQEVNVPAGETSVR 293
Query: 1415 LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISW-DAPAV 1473
L L P TEY V+++AL + G T + +L + T SLL++W P
Sbjct: 294 LRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGPELTIQNTTAHSLLVAWRSVPGA 353
Query: 1474 TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKP 1533
T YR+T+ G Q+ PG S + L+PG DY +TV + GR PA+S
Sbjct: 354 TG--YRVTWRVLSGGPTQQQELGPGQGSVL-LRDLEPGTDYEVTVSTLFGRSVGPATS-- 408
Query: 1534 ISINYRTEIDKPSQMQVTDVQDNSISVKW--LPSSSPVTGYRVTTTPKNGPGPTKTKTAG 1591
+ RT+ ++ + SI + W +P + GYR+ + G P +
Sbjct: 409 --LMARTDASVEQTLRPVILGPTSILLSWNLVPEAR---GYRLEWRRETGLEPPQKVVLP 463
Query: 1592 PDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKG----LAFTDVDVDS 1647
D T ++GLQP EY +++Y E T + P L T++
Sbjct: 464 SDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPVSPVTDLQATELPGQR 523
Query: 1648 IKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD 1707
++++W SP ++YR+ S + G+ P G + +L ++ G YTV V A
Sbjct: 524 VRVSW-SPVPGATQYRIIVRSTQ-GVERTLVLP-GSQTAFDLDDVQAGLSYTVRVSARVG 580
Query: 1708 DMESQPLIGT----QSTAIPAPTDLKFTQVTPTSLSAQWTP-PNVQLTGYRVRVTPKEKT 1762
E + T T + P L+ T + W P P +G+R+ + +
Sbjct: 581 PREGSASVLTVRREPETPLAVP-GLRVVVSDATRVRVAWGPVPGA--SGFRISWSTG--S 635
Query: 1763 GPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARV 1822
GP L PDS++ ++GL T Y+V+V L+ PA +V + + P R V
Sbjct: 636 GPESSQTLPPDSTATDITGLQPGTTYQVAVSVLRGR-EEGPAAVIVARTDPLGPVRTVHV 694
Query: 1823 TDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIY 1882
T A+ +++TI+W T+ TG++V A+G Q + + + GL+P T+Y ++
Sbjct: 695 TQASSSSVTITW-TRVPGATGYRVSWHSAHGPEKSQ-LVSGEATVAELDGLEPDTEYTVH 752
Query: 1883 LYTLN---DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEK 1939
+ D +S VV A + S L+ L + + L ++W +
Sbjct: 753 VRAHVAGVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVTGATAYRLAWGRS 812
Query: 1940 PGSPPREVVPRPRPGVTE-ATITGLEPGTEYTIYVIALKNNQKSEP--LIGRKKTDELPQ 1996
G P R + PG T+ A I GLE G Y++ V AL +++ P ++ + P
Sbjct: 813 EGGPMRHQI---LPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVTTPPEAPPA 869
Query: 1997 LVTL---------------PHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSG 2041
L TL P P G + P Q+ V P + + G
Sbjct: 870 LGTLHVVQRGEHSLRLRWEPVPRAQGFLLHWQPEGGQEQSRVLGPELSSYH------LDG 923
Query: 2042 QQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPR--PYPPNVGQEALSQTTISWAPFQDTS 2099
+P+ ++ G P T PR V ++ T++W P S
Sbjct: 924 LEPATQYRVRLSVLGPAGEGPSAEVTARTESPRVPSIELRVVDTSIDSVTLAWTPVSRAS 983
Query: 2100 EYIISCHPV---GTDEEPLQFRVPGTSTSATLTGLTRGATY 2137
YI+S P+ G + +PG S+S +TGL G +Y
Sbjct: 984 SYILSWRPLRGPGQEVPGSPQTLPGISSSQRVTGLEPGVSY 1024
Score = 200 bits (508), Expect = 2e-50
Identities = 217/826 (26%), Positives = 348/826 (42%), Gaps = 60/826 (7%)
Query: 1096 TEVTETTIVITWTPA--PRIGFKLGVRPSQGGEAP-----REVTSDSG--SIVVSGLTPG 1146
+E + ++ + WT A P G+K+ P G P +EV +G S+ + GL P
Sbjct: 241 SEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQEVNVPAGETSVRLRGLRPL 300
Query: 1147 VEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGY 1206
EY T+ L +A T L P L ++ N L V+W + P TGY
Sbjct: 301 TEYQVTVIALYANSIGEAVSGTARTTALEGP-ELTIQ-NTTAHSLLVAWR--SVPGATGY 356
Query: 1207 RITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPA 1266
R+T +G G + ++ + Q S +L PG +Y V+V T+ S
Sbjct: 357 RVTWRVLSG--GPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTLFGRSVGPATSLMARTD 414
Query: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326
LR +GP ++ ++W P + + + + E ++ + L
Sbjct: 415 ASVEQTLRPVILGPTSILLSWNLVP--EARGYRLEWRRETGLEPPQKVVLPSDVTRYQLD 472
Query: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP----TGIDFSDITANSFTVHWIAPR 1382
L PGTEY +++ ++ E HE TG + P T + +++ V W +P
Sbjct: 473 GLQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPVSPVTDLQATELPGQRVRVSW-SPV 531
Query: 1383 ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE---SPL 1439
T YRI G R +P S+ + L ++ G Y V + A G E S L
Sbjct: 532 PGATQYRIIVRSTQ--GVERTLVLPGSQTAFDLDDVQAGLSYTVRVSARVGPREGSASVL 589
Query: 1440 LIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGS 1499
+ ++ L VV + T + ++W P +RI++ G+ P T+P
Sbjct: 590 TVRREPETPLAVPGLRVVVSDATRVRVAW-GPVPGASGFRISWST--GSGPESSQTLPPD 646
Query: 1500 KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ-MQVTDVQDNSI 1558
+ I+GL+PG Y + V + GR + PA+ I RT+ P + + VT +S+
Sbjct: 647 STATDITGLQPGTTYQVAVSVLRGREEGPAAV----IVARTDPLGPVRTVHVTQASSSSV 702
Query: 1559 SVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPS 1618
++ W TGYRV+ + GP K++ + T ++GL+P EY V V A
Sbjct: 703 TITWTRVPG-ATGYRVSW--HSAHGPEKSQLVSGEATVAELDGLEPDTEYTVHVRAHVAG 759
Query: 1619 GESQP---LVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGI-- 1673
+ P +V+TA + R L + D ++I W G + YR+ + E G
Sbjct: 760 VDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVTGATA-YRLAWGRSEGGPMR 818
Query: 1674 HELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPL---IGTQSTAIPAPTDLKF 1730
H++ P G D+AE++GL G Y+V V AL D E P+ + T A PA L
Sbjct: 819 HQILP---GNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVTTPPEAPPALGTLHV 875
Query: 1731 TQVTPTSLSAQWTP-PNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 1789
Q SL +W P P Q G+ + P+ G + L P+ SS + GL AT+Y
Sbjct: 876 VQRGEHSLRLRWEPVPRAQ--GFLLHWQPEG--GQEQSRVLGPELSSYHLDGLEPATQYR 931
Query: 1790 VSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAV 1849
V + L A+ T P RV D + ++T++W T + + +
Sbjct: 932 VRLSVLGPAGEGPSAEVTARTESPRVPSIELRVVDTSIDSVTLAW-TPVSRASSYILSWR 990
Query: 1850 PANG---QTPIQRTIKPDVRS-YTITGLQPGTDYKIYLYTLNDNAR 1891
P G + P P + S +TGL+PG Y L + D R
Sbjct: 991 PLRGPGQEVPGSPQTLPGISSSQRVTGLEPGVSYIFSLTPVLDGVR 1036
Score = 197 bits (502), Expect = 8e-50
Identities = 198/816 (24%), Positives = 346/816 (42%), Gaps = 45/816 (5%)
Query: 1257 VPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN-----EEDV 1311
VP++ + P DL + ++RV W S +T + V+Y+P+ +
Sbjct: 222 VPVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAA-SGPVTGYKVQYTPLTGLGQPLPSER 280
Query: 1312 AELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITA 1371
E+++ + +V L L P TEY V+V ++Y + G +T + + TA
Sbjct: 281 QEVNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGPELTIQNTTA 340
Query: 1372 NSFTVHWIAPRATITGYRIRHHPEHFSGRP-REDRVPHSRNSITLTNLTPGTEYVVSIVA 1430
+S V W + TGYR+ SG P ++ + + S+ L +L PGT+Y V++
Sbjct: 341 HSLLVAWRSVPGA-TGYRVTWRV--LSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVST 397
Query: 1431 LNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSP 1490
L GR P T + V + L V PTS+L+SW+ R YR+ + G P
Sbjct: 398 LFGRSVGPATSLMARTDASVEQTLRPVILGPTSILLSWNL-VPEARGYRLEWRRETGLEP 456
Query: 1491 VQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQV 1550
Q+ +P + + GL+PG +Y +T+Y + + + + + + +Q
Sbjct: 457 PQKVVLPSDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPVSPVTDLQA 516
Query: 1551 TDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVV 1610
T++ + V W P T YR+ ++ G +T QT ++ +Q + Y V
Sbjct: 517 TELPGQRVRVSWSPVPG-ATQYRIIV--RSTQGVERTLVLPGSQTAFDLDDVQAGLSYTV 573
Query: 1611 SVYAQNPSGESQPLVQTAVTNIDRP---KGLAFTDVDVDSIKIAWESPQGQVSRYRVTYS 1667
V A+ E V T + P GL D +++AW P S +R+++S
Sbjct: 574 RVSARVGPREGSASVLTVRREPETPLAVPGLRVVVSDATRVRVAW-GPVPGASGFRISWS 632
Query: 1668 SPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT- 1726
+ PD ++ GL+PG+ Y V+V L E + T P
Sbjct: 633 TGSGPESSQTLPPD--STATDITGLQPGTTYQVAVSVLRGREEGPAAVIVARTDPLGPVR 690
Query: 1727 DLKFTQVTPTSLSAQWT-PPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVA 1785
+ TQ + +S++ WT P TGY RV+ GP K ++ +++ + GL
Sbjct: 691 TVHVTQASSSSVTITWTRVPGA--TGY--RVSWHSAHGPEKSQLVSGEATVAELDGLEPD 746
Query: 1786 TKYEVSVYALKDTLTSRPAQGVVTTL-ENVSPPRRARVTDATETTITISWRTKTETITGF 1844
T+Y V V A + PA VV T E V R ++ +A+ + I+W T T +
Sbjct: 747 TEYTVHVRAHVAGVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVTGA-TAY 805
Query: 1845 QVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAID 1904
++ + G + + + S I GL+ G Y + + L + +PV I +T +
Sbjct: 806 RLAWGRSEGGPMRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVTTPPE 865
Query: 1905 AP---SNLRFLATTPNSLLVSWQP-PRARITGYIIKYEKPGSPPREVVPRPRPGVTEATI 1960
AP L + +SL + W+P PRA+ G+++ ++ G + V P ++ +
Sbjct: 866 APPALGTLHVVQRGEHSLRLRWEPVPRAQ--GFLLHWQPEGGQEQSRVLGPE--LSSYHL 921
Query: 1961 TGLEPGTEYTI--YVIALKNNQKSEPLIGRKKTDELPQL------VTLPHPNLHGPEILD 2012
GLEP T+Y + V+ S + R ++ +P + ++ L +
Sbjct: 922 DGLEPATQYRVRLSVLGPAGEGPSAEVTARTESPRVPSIELRVVDTSIDSVTLAWTPVSR 981
Query: 2013 VPSTVQKTPFVTHPGYDT-GNGIQLPGTSGQQPSVG 2047
S + + PG + G+ LPG S Q G
Sbjct: 982 ASSYILSWRPLRGPGQEVPGSPQTLPGISSSQRVTG 1017
Score = 194 bits (494), Expect = 7e-49
Identities = 220/875 (25%), Positives = 369/875 (42%), Gaps = 72/875 (8%)
Query: 696 DFTTTSTSTPVTSN----TVTGETTPFSPLVATSES----VTEITASSFVVSWVSASDTV 747
DF+ T P+ S T G P +TS ++E ++ S V W +AS V
Sbjct: 200 DFSILRTLLPLVSRRVCTTAGGVPVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPV 259
Query: 748 SGFRVEYE-LSEEGD----EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLI 802
+G++V+Y L+ G E Q +++P+ TSV + L P +Y V V + + +
Sbjct: 260 TGYKVQYTPLTGLGQPLPSERQEVNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAV 319
Query: 803 LSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETA 862
T++TTA + P + T+ S++V W R TGYR+ + G + + L
Sbjct: 320 SGTARTTALEGP-ELTIQNTTAHSLLVAW-RSVPGATGYRVTWRVLSGGPTQQQELGPGQ 377
Query: 863 NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK 922
SV L DL+PG Y +T+ + + T + P V +
Sbjct: 378 GSVLLRDLEPGTDYEVTVSTLFGRSVGPATSLMARTDASVEQTLRP-------VILGPTS 430
Query: 923 VTIMWTPPESAVTGYRVDVI-PVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVS 981
+ + W A GYR++ L LP S T ++ GL PG Y ++ +
Sbjct: 431 ILLSWNLVPEA-RGYRLEWRRETGLEPPQKVVLP-SDVTRYQLDGLQPGTEYRLTLYTLL 488
Query: 982 HGRE-SKPLTAQQT---TKLDAPTNLQFVNETDSTVLVRWTP-PRAQITGYRLTVGLTRR 1036
G E + P T T + T+LQ V V W+P P A T YR+ V T+
Sbjct: 489 EGHEVATPATVVPTGPELPVSPVTDLQATELPGQRVRVSWSPVPGA--TQYRIIVRSTQ- 545
Query: 1037 GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGS--SIPPY 1094
G R + S + + L ++Q YTV + A G +E A+ + +P + ++P
Sbjct: 546 GVERTLVLPGSQTAFDLDDVQAGLSYTVRVSARVGPREG-SASVLTVRREPETPLAVPGL 604
Query: 1095 NTEVTETTIV-ITWTPAPRI-GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYT 1152
V++ T V + W P P GF++ G E+ + + DS + ++GL PG Y
Sbjct: 605 RVVVSDATRVRVAWGPVPGASGFRISWSTGSGPESSQTLPPDSTATDITGLQPGTTYQVA 664
Query: 1153 IQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTP 1212
+ VLR +E A ++ PL P +H+ + V T++W R P TGYR++
Sbjct: 665 VSVLRGREEGPAAVIVARTDPLGPVRTVHVTQASSSSV-TITWTR--VPGATGYRVSWHS 721
Query: 1213 TNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPP-- 1270
+G + + L V + + D L P EY V V + P S ++ P P
Sbjct: 722 AHGPEKSQL---VSGEATVAELDGLEPDTEYTVHVRAHVAGVDGPPAS-VVVRTAPEPVG 777
Query: 1271 --TDLRFTNIGPDTMRVTWAPPPSIDLTNFLV-RYSPVKNEEDVAELSISPSD-NAVVLT 1326
+ L+ N D +R+TW + +T R + ++E I P + ++ +
Sbjct: 778 RVSRLQILNASSDVLRITW-----VGVTGATAYRLAWGRSEGGPMRHQILPGNTDSAEIR 832
Query: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDIT---ANSFTVHWIAPRA 1383
L G Y V V+++ E TP+ T ++P + + +S + W P
Sbjct: 833 GLEGGVSYSVRVTALVGDREGTPVSIVVTTPPEAPPALGTLHVVQRGEHSLRLRW-EPVP 891
Query: 1384 TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQ 1443
G+ + PE G+ + + +S L L P T+Y V + L E P +
Sbjct: 892 RAQGFLLHWQPE--GGQEQSRVLGPELSSYHLDGLEPATQYRVRLSVLGPAGEGP--SAE 947
Query: 1444 QSTVSDVPR----DLEVVAATPTSLLISWDAPAVTVRYYRITYGE---TGGNSPVQEFTV 1496
+ ++ PR +L VV + S+ ++W P Y +++ G P T+
Sbjct: 948 VTARTESPRVPSIELRVVDTSIDSVTLAW-TPVSRASSYILSWRPLRGPGQEVPGSPQTL 1006
Query: 1497 PGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS 1531
PG S+ ++GL+PGV Y ++ V P +S
Sbjct: 1007 PGISSSQRVTGLEPGVSYIFSLTPVLDGVRGPEAS 1041
Score = 180 bits (457), Expect = 1e-44
Identities = 220/885 (24%), Positives = 367/885 (41%), Gaps = 86/885 (9%)
Query: 607 SSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGR-----WKEATIPG 661
S+S P ++ ++E SQ S +QW A ++ Y +++ P +G+ +E +P
Sbjct: 231 STSAPRDLVLSEPSSQ--SLRVQWTAAS-GPVTGYKVQYTPLTGLGQPLPSERQEVNVPA 287
Query: 662 HLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPL 721
S ++GL+P Y+ +I++ E TT+ P
Sbjct: 288 GETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGP---------------- 331
Query: 722 VATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLL 781
++ TA S +V+W S +G+RV + + G Q +L SV + DL
Sbjct: 332 ---ELTIQNTTAHSLLVAWRSVPG-ATGYRVTWRVL-SGGPTQQQELGPGQGSVLLRDLE 386
Query: 782 PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV--DDTSIVVRWSR-PQAPI 838
PG Y V V + +S+ +TS DA + T+ V TSI++ W+ P+A
Sbjct: 387 PGTDYEVTVSTLF---GRSVGPATSLMARTDASVEQTLRPVILGPTSILLSWNLVPEA-- 441
Query: 839 TGYRIVYSPSVE-GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQE-STPVVIQQ 896
GYR+ + ++ LP L LQPG +Y +T+Y + E E +TP +
Sbjct: 442 RGYRLEWRRETGLEPPQKVVLPSDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPATVVP 501
Query: 897 ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPI 956
P S DLQ E+ +V + W+P A T YR+ ++ E LP
Sbjct: 502 TGPELPVSPVT----DLQATELPGQRVRVSWSPVPGA-TQYRI-IVRSTQGVERTLVLPG 555
Query: 957 SRNTFAEVTGLSPGVTYYFKVFAVSHGRESK----PLTAQQTTKLDAPTNLQFVNETDST 1012
S+ F ++ + G++Y +V A RE + + T L P L+ V +
Sbjct: 556 SQTAF-DLDDVQAGLSYTVRVSARVGPREGSASVLTVRREPETPLAVP-GLRVVVSDATR 613
Query: 1013 VLVRWTP-PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKG 1071
V V W P P A +G+R++ T G + P + + LQP + Y V++ ++G
Sbjct: 614 VRVAWGPVPGA--SGFRISWS-TGSGPESSQTLPPDSTATDITGLQPGTTYQVAVSVLRG 670
Query: 1072 NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP-RIGFKLGVRPSQGGEAPRE 1130
+E P A V T G + T+ + +++ ITWT P G+++ + G E +
Sbjct: 671 REEGPAAVIVARTDPLGPVRTVHVTQASSSSVTITWTRVPGATGYRVSWHSAHGPEKSQL 730
Query: 1131 VTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAP----IVNKVVTPLSPPTNLHLEANP 1186
V+ ++ + GL P E YT+ V D P +V P+ + L + N
Sbjct: 731 VSGEATVAELDGLEPDTE--YTVHVRAHVAGVDGPPASVVVRTAPEPVGRVSRLQI-LNA 787
Query: 1187 DTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVS 1246
+ VL ++W T T YR+ + G G +++ + S L G+ Y+V
Sbjct: 788 SSDVLRITWVGVT--GATAYRLAWGRSEG--GPMRHQILPGNTDSAEIRGLEGGVSYSVR 843
Query: 1247 VYTVKDDKESVPISDTII--PAVPPPT-DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYS 1303
V + D+E P+S + P PP L G ++R+ W P P FL+ +
Sbjct: 844 VTALVGDREGTPVSIVVTTPPEAPPALGTLHVVQRGEHSLRLRWEPVPRAQ--GFLLHWQ 901
Query: 1304 PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG 1363
P +E L P ++ L L P T+Y V +S + E +T
Sbjct: 902 PEGGQEQSRVL--GPELSSYHLDGLEPATQYRVRLSVLGPAGEGPSAEVTARTESPRVPS 959
Query: 1364 IDFS--DITANSFTVHWIAPRATITGYRIRHHP-----EHFSGRPREDRVPHSRNSITLT 1416
I+ D + +S T+ W P + + Y + P + G P+ +P +S +T
Sbjct: 960 IELRVVDTSIDSVTLAW-TPVSRASSYILSWRPLRGPGQEVPGSPQ--TLPGISSSQRVT 1016
Query: 1417 NLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATP 1461
L PG Y+ S+ + P Q+ V PR L V P
Sbjct: 1017 GLEPGVSYIFSLTPVLDGVRGPEASVTQTPV--CPRGLADVVFLP 1059
Score = 159 bits (402), Expect = 3e-38
Identities = 181/720 (25%), Positives = 287/720 (39%), Gaps = 66/720 (9%)
Query: 562 QDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQPLQTYPSSSGPVEVFITETPS 621
+D E GT Y++ S +GR +G +T S VE +
Sbjct: 383 RDLEPGTDYEVTVST------------LFGRSVGPATSLMARTDAS----VEQTLRPVIL 426
Query: 622 QPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQL 681
P S + WN + Y L WR + + ++ +P + Y + GL+PG Y L
Sbjct: 427 GPTSILLSWNLVPEAR--GYRLEWRRETGLEPPQKVVLPSDVTRYQLDGLQPGTEYRLTL 484
Query: 682 ISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV 741
++ + GH+ +TP T TG P SP+ T TE+ VSW
Sbjct: 485 YTLLE-GHE-----------VATPATV-VPTGPELPVSPV--TDLQATELPGQRVRVSW- 528
Query: 742 SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQI--SEDGEQ 799
S + +R+ S +G E + L LP + T+ ++ D+ G Y V V +G
Sbjct: 529 SPVPGATQYRIIVR-STQGVE-RTLVLPGSQTAFDLDDVQAGLSYTVRVSARVGPREGSA 586
Query: 800 SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP 859
S++ + P A P V D T + V W P +G+RI +S G + LP
Sbjct: 587 SVLTVRREPETPLAVPGLRVVVSDATRVRVAWG-PVPGASGFRISWSTG-SGPESSQTLP 644
Query: 860 ETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVT 919
+ + ++ LQPG Y + + + +E VI R+D + R + + +
Sbjct: 645 PDSTATDITGLQPGTTYQVAVSVLRGREEGPAAVI------VARTDPLGPVRTVHVTQAS 698
Query: 920 DVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA 979
VTI WT A TGYRV + G +L T AE+ GL P Y V A
Sbjct: 699 SSSVTITWTRVPGA-TGYRVSWHSAH--GPEKSQLVSGEATVAELDGLEPDTEYTVHVRA 755
Query: 980 VSHGRESKPLTAQQTT---KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRR 1036
G + P + T + + LQ +N + + + W T YRL G +
Sbjct: 756 HVAGVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVTG-ATAYRLAWGRSEG 814
Query: 1037 GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT 1096
G R + + +R L+ Y+V + A+ G++E + V TT P + P T
Sbjct: 815 GPMRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVTT--PPEAPPALGT 872
Query: 1097 ----EVTETTIVITWTPAPRI-GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVY 1151
+ E ++ + W P PR GF L +P G E R + + S + GL P +Y
Sbjct: 873 LHVVQRGEHSLRLRWEPVPRAQGFLLHWQPEGGQEQSRVLGPELSSYHLDGLEPATQYRV 932
Query: 1152 TIQVLRD-GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITT 1210
+ VL G+ A + + +P P L + DT + +V+ + + Y ++
Sbjct: 933 RLSVLGPAGEGPSAEVTARTESPRVPSIELRV---VDTSIDSVTLAWTPVSRASSYILSW 989
Query: 1211 TPTN--GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVP 1268
P GQ+ + + SS L PG+ Y S+ V D S T P P
Sbjct: 990 RPLRGPGQEVPGSPQTLPGISSSQRVTGLEPGVSYIFSLTPVLDGVRGPEASVTQTPVCP 1049
Score = 122 bits (307), Expect = 3e-27
Identities = 154/668 (23%), Positives = 266/668 (39%), Gaps = 75/668 (11%)
Query: 1521 VTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKN 1580
V+ R + A P++ P + +++ S+ V+W +S PVTGY+V TP
Sbjct: 211 VSRRVCTTAGGVPVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLT 270
Query: 1581 G-----PGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRP 1635
G P + +T + + GL+P EY V+V A + + + TA T
Sbjct: 271 GLGQPLPSERQEVNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEG 330
Query: 1636 KGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDG---IHELFPAPDGEEDTAELQGL 1692
L + S+ +AW S G + YRVT+ G EL P + + L+ L
Sbjct: 331 PELTIQNTTAHSLLVAWRSVPG-ATGYRVTWRVLSGGPTQQQELGPG----QGSVLLRDL 385
Query: 1693 RPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQ------VTPTSLSAQWTPPN 1746
PG++Y V+V L +T++ A TD Q + PTS+ W
Sbjct: 386 EPGTDYEVTVSTLFGRSVG------PATSLMARTDASVEQTLRPVILGPTSILLSWNLV- 438
Query: 1747 VQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYA-LKDTLTSRPAQ 1805
+ GYR+ + P +++ L D + + GL T+Y +++Y L+ + PA
Sbjct: 439 PEARGYRLEWRRETGLEPPQKVVLPSDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPAT 498
Query: 1806 GVVTTLE-NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT--IK 1862
V T E VSP + T+ + +SW + G + ++RT +
Sbjct: 499 VVPTGPELPVSPVTDLQATELPGQRVRVSW----SPVPGATQYRIIVRSTQGVERTLVLP 554
Query: 1863 PDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP---SNLRFLATTPNSL 1919
++ + +Q G Y + + S V+ + P LR + + +
Sbjct: 555 GSQTAFDLDDVQAGLSYTVRVSARVGPREGSASVLTVRREPETPLAVPGLRVVVSDATRV 614
Query: 1920 LVSWQP-PRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKN 1978
V+W P P A +G+ I + GS P P P T ITGL+PGT Y + V L+
Sbjct: 615 RVAWGPVPGA--SGFRISW-STGSGPESSQTLP-PDSTATDITGLQPGTTYQVAVSVLRG 670
Query: 1979 NQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPG 2038
++ + +TD L + T+ + S+ + PG TG +
Sbjct: 671 REEGPAAVIVARTDPLGPVRTV--------HVTQASSSSVTITWTRVPG-ATGYRVSWHS 721
Query: 2039 TSGQQPS---VGQQMIFEEHGFRRTTP--------------PTTATPIRHRPRPYPPNVG 2081
G + S G+ + E G T P + +R P P
Sbjct: 722 AHGPEKSQLVSGEATVAELDGLEPDTEYTVHVRAHVAGVDGPPASVVVRTAPEPVGRVSR 781
Query: 2082 QEALSQTT----ISWAPFQDTSEYIISCHPVGTDEEPLQFRV-PGTSTSATLTGLTRGAT 2136
+ L+ ++ I+W + Y ++ ++ P++ ++ PG + SA + GL G +
Sbjct: 782 LQILNASSDVLRITWVGVTGATAYRLAWG--RSEGGPMRHQILPGNTDSAEIRGLEGGVS 839
Query: 2137 YNIIVEAL 2144
Y++ V AL
Sbjct: 840 YSVRVTAL 847
Score = 117 bits (294), Expect = 1e-25
Identities = 124/467 (26%), Positives = 199/467 (42%), Gaps = 48/467 (10%)
Query: 1713 PLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGP-----MKE 1767
P+ + AP DL ++ + SL QWT + +TGY+V+ TP G +E
Sbjct: 223 PVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQE 282
Query: 1768 INLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATE 1827
+N+ +SV + GL T+Y+V+V AL G T P + + T
Sbjct: 283 VNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGP--ELTIQNTTA 340
Query: 1828 TTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1887
++ ++WR+ TG++V +G Q+ + P S + L+PGTDY++ + TL
Sbjct: 341 HSLLVAWRS-VPGATGYRVTWRVLSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTLF 399
Query: 1888 DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQ-PPRARITGYIIKYEKPGS--PP 1944
+ + A T LR + P S+L+SW P AR GY +++ + PP
Sbjct: 400 GRSVGPATSLMARTDASVEQTLRPVILGPTSILLSWNLVPEAR--GYRLEWRRETGLEPP 457
Query: 1945 REVVPRPRPGVTEATITGLEPGTEY--TIYVIALKNNQKSEPLIGRKKTDELPQLVTLPH 2002
++VV VT + GL+PGTEY T+Y + L+ ++ + P ELP P
Sbjct: 458 QKVVLPS--DVTRYQLDGLQPGTEYRLTLYTL-LEGHEVATPATVVPTGPELP---VSPV 511
Query: 2003 PNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSV---GQQMIFEEHGFRR 2059
+L E+ V +P PG T I + T G + ++ G Q F+ +
Sbjct: 512 TDLQATELPGQRVRVSWSPV---PGA-TQYRIIVRSTQGVERTLVLPGSQTAFDLDDVQA 567
Query: 2060 TTPPTTATPIRHRPR------------PYPP------NVGQEALSQTTISWAPFQDTSEY 2101
T R PR P P V ++ ++W P S +
Sbjct: 568 GLSYTVRVSARVGPREGSASVLTVRREPETPLAVPGLRVVVSDATRVRVAWGPVPGASGF 627
Query: 2102 IISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQ 2148
IS G+ E Q +P ST+ +TGL G TY + V L+ ++
Sbjct: 628 RISWS-TGSGPESSQ-TLPPDSTATDITGLQPGTTYQVAVSVLRGRE 672
>gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]
Length = 1796
Score = 209 bits (531), Expect = 3e-53
Identities = 177/706 (25%), Positives = 316/706 (44%), Gaps = 55/706 (7%)
Query: 1219 NSLEEVVHADQSS-----CTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDL 1273
N L+E+ S+ FD + +E + +++ I + PPT+L
Sbjct: 300 NELQEIASEPDSTHVYNVAEFDLMHTVVESLTRTLCSRVEEQDREIKASAHAITGPPTEL 359
Query: 1274 RFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTE 1333
+ + + V W P ++ + V Y P + + E+ + + ++ VL NL+ TE
Sbjct: 360 ITSEVTARSFMVNWTHAPG-NVEKYRVVYYPTRGGKP-DEVVVDGTVSSTVLKNLMSLTE 417
Query: 1334 YVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRH 1392
Y ++V ++Y S LRG + T L + + D+T NS V W A +GY I +
Sbjct: 418 YQIAVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPGA-SGYLILY 476
Query: 1393 HP--EHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-D 1449
P E +G +E ++ + I L+ L P TEY V++ A+ G E S + GQ++T++
Sbjct: 477 APLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQETTLALS 536
Query: 1450 VPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLK 1509
PR+L + S ++WD + + YRI Y G + E V +T + GL
Sbjct: 537 PPRNLRISNVGSNSARLTWDPTSRQINGYRIVYNNADGTE-INEVEVDPI-TTFPLKGLT 594
Query: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ--MQVTDVQDNSISVKWLPSSS 1567
P +YTI ++++ G S +P++ + TE + P+Q +++ +V +S V W P S+
Sbjct: 595 PLTEYTIAIFSIYDEGQS----EPLTGVFTTE-EVPAQQYLEIDEVTTDSFRVTWHPLSA 649
Query: 1568 PVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT 1627
+++ P G G T+ +Q IEGL+P EY VS+ A G +V
Sbjct: 650 DEGLHKLMWIPVYG-GKTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTA 708
Query: 1628 AVTNIDR----------------------PKGLAFTDVDVDSIKIAWESPQGQVSRYRVT 1665
T +D + L D S+++ W+ V ++RVT
Sbjct: 709 VGTTLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVT 768
Query: 1666 YSS----PEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA 1721
Y + PE+ + P G ++ L+ L P +EY V+V ++ D E + T
Sbjct: 769 YMTAQGDPEEEVIGTVMVP-GSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAPGKT- 826
Query: 1722 IPA--PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1779
+P+ P +L+ ++ L W PP+ + GYR+ P GP E + D +++++
Sbjct: 827 LPSSGPQNLRVSEEWYNRLRITWDPPSSPVKGYRIVYKPVSVPGPTLETFVGADINTILI 886
Query: 1780 SGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTE 1839
+ L+ Y V ++A + + S G+V TL +A+ + T++ W+
Sbjct: 887 TNLLSGMDYNVKIFASQASGFSDALTGMVKTLFLGVTNLQAKHVEM--TSLCAHWQVHRH 944
Query: 1840 TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYT 1885
T ++V + + T+ + GLQP ++YKI +YT
Sbjct: 945 A-TAYRVVIESLQDRQKQESTVGGGTTRHCFYGLQPDSEYKISVYT 989
Score = 201 bits (510), Expect = 9e-51
Identities = 184/688 (26%), Positives = 292/688 (42%), Gaps = 53/688 (7%)
Query: 795 EDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSST 854
E+ ++ + S T P P + +V S +V W+ + YR+VY P+ G
Sbjct: 339 EEQDREIKASAHAITGP--PTELITSEVTARSFMVNWTHAPGNVEKYRVVYYPTRGGKPD 396
Query: 855 ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQ 914
E+ + T +S L +L +Y I ++A+ + S + GT + +P DL
Sbjct: 397 EVVVDGTVSSTVLKNLMSLTEYQIAVFAIYAHTAS------EGLRGTETTLALPMASDLL 450
Query: 915 FVEVTDVKVTIMWTPPESAVTGYRVDVIPV--NLPGEHGQRLPISRNTFAEVTGLSPGVT 972
+VT+ + + W A +GY + P+ L G+ + +T E++GL P
Sbjct: 451 LYDVTENSMRVKWDAVPGA-SGYLILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTE 509
Query: 973 YYFKVFAVSHGRESKPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031
Y V+A+ S P+T Q+TT L P NL+ N ++ + W P QI GYR+
Sbjct: 510 YTVTVYAMFGEEASDPVTGQETTLALSPPRNLRISNVGSNSARLTWDPTSRQINGYRIVY 569
Query: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSI 1091
+ + V P ++ +PL+ L P +EYT+++ +I +S TGVFTT + +
Sbjct: 570 NNADGTEINEVEVDP-ITTFPLKGLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVPAQQ 628
Query: 1092 PPYNTEVTETTIVITWTP--APRIGFKLGVRPSQGGEAPREV-TSDSGSIVVSGLTPGVE 1148
EVT + +TW P A KL P GG+ V + S V+ GL PG E
Sbjct: 629 YLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGGKTEEVVLKEEQDSHVIEGLEPGTE 688
Query: 1149 Y-VYTIQVLRDGQERDAPIV---------NKVVTPLSPPTNLH----------LEANPDT 1188
Y V + VL DG E + + T + P T++ + + T
Sbjct: 689 YEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETT 748
Query: 1189 GVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEV-----VHADQSSCTFDNLSPGLEY 1243
L V W+ S + D+ +R+T QG+ EEV V Q++ L P EY
Sbjct: 749 SSLRVKWDISDS-DVQQFRVTYMTA---QGDPEEEVIGTVMVPGSQNNLLLKPLLPDTEY 804
Query: 1244 NVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301
V+V + D E V +S +P+ P +LR + + +R+TW PPS + + +
Sbjct: 805 KVTVTPIYTDGEGVSVSAPGKTLPS-SGPQNLRVSEEWYNRLRITW-DPPSSPVKGYRIV 862
Query: 1302 YSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP 1361
Y PV E + N +++TNLL G +Y V + + S L G KT
Sbjct: 863 YKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQASGFSDALTGMVKTLFLGV 922
Query: 1362 TGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPR-EDRVPHSRNSITLTNLTP 1420
T + + S HW R T YR+ E R + E V L P
Sbjct: 923 TNLQAKHVEMTSLCAHWQVHRHA-TAYRV--VIESLQDRQKQESTVGGGTTRHCFYGLQP 979
Query: 1421 GTEYVVSIVALNGREESPLLIGQQSTVS 1448
+EY +S+ E P + + T S
Sbjct: 980 DSEYKISVYTKLQEIEGPSVSIMEKTQS 1007
Score = 190 bits (482), Expect = 2e-47
Identities = 177/665 (26%), Positives = 292/665 (43%), Gaps = 50/665 (7%)
Query: 1096 TEVTETTIVITWTPAPRIGFKLGV--RPSQGGEAPREVTSDS--GSIVVSGLTPGVEYVY 1151
+EVT + ++ WT AP K V P++GG+ P EV D S V+ L EY
Sbjct: 362 SEVTARSFMVNWTHAPGNVEKYRVVYYPTRGGK-PDEVVVDGTVSSTVLKNLMSLTEYQI 420
Query: 1152 TIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTT 1211
+ + + + L ++L L + + V W+ P +GY I
Sbjct: 421 AVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENS-MRVKWD--AVPGASGYLILYA 477
Query: 1212 P-TNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVP 1268
P T G G+ E + + L P EY V+VY + ++ S P++ +T + A+
Sbjct: 478 PLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQETTL-ALS 536
Query: 1269 PPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNL 1328
PP +LR +N+G ++ R+TW P S + + + Y+ E + E+ + P L L
Sbjct: 537 PPRNLRISNVGSNSARLTW-DPTSRQINGYRIVYNNADGTE-INEVEVDPI-TTFPLKGL 593
Query: 1329 LPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITANSFTVHWIAPRATITG 1387
P TEY +++ S+Y++ +S PL G T + + ++ ++T +SF V W A
Sbjct: 594 TPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVPAQQYLEIDEVTTDSFRVTWHPLSADEGL 653
Query: 1388 YRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVA-LNGREESPLLIGQQST 1446
+++ P + G+ E + ++S + L PGTEY VS++A L+ ES ++ +T
Sbjct: 654 HKLMWIPV-YGGKTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTT 712
Query: 1447 VSD---------VP------------RDLEVVAATPTSLLISWDAPAVTVRYYRITYGET 1485
+ VP R+L V T +SL + WD V+ +R+TY
Sbjct: 713 LDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMTA 772
Query: 1486 GGNSPVQEFT----VPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTE 1541
G+ P +E VPGS++ + L P +Y +TV + G+ + S P
Sbjct: 773 QGD-PEEEVIGTVMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAP---GKTLP 828
Query: 1542 IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG 1601
P ++V++ N + + W P SSPV GYR+ P + PGPT G D + I
Sbjct: 829 SSGPQNLRVSEEWYNRLRITWDPPSSPVKGYRIVYKPVSVPGPTLETFVGADINTILITN 888
Query: 1602 LQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSR 1661
L ++Y V ++A SG S L T L V++ S+ W+ + +
Sbjct: 889 LLSGMDYNVKIFASQASGFSDALTGMVKTLFLGVTNLQAKHVEMTSLCAHWQVHR-HATA 947
Query: 1662 YRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA 1721
YRV S +D + G GL+P SEY +SV ++E P +
Sbjct: 948 YRVVIESLQDRQKQESTVGGGTTRHC-FYGLQPDSEYKISVYTKLQEIEG-PSVSIMEKT 1005
Query: 1722 IPAPT 1726
PT
Sbjct: 1006 QSLPT 1010
Score = 186 bits (473), Expect = 2e-46
Identities = 180/673 (26%), Positives = 283/673 (42%), Gaps = 53/673 (7%)
Query: 1000 PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPA 1059
PT L T + +V WT + YR+ TR G+P + V +VS L+NL
Sbjct: 356 PTELITSEVTARSFMVNWTHAPGNVEKYRVVYYPTRGGKPDEVVVDGTVSSTVLKNLMSL 415
Query: 1060 SEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP-RIGFKLG 1118
+EY +++ AI + S G TTL + +VTE ++ + W P G+ +
Sbjct: 416 TEYQIAVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPGASGYLIL 475
Query: 1119 VRP----SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT-P 1173
P G E ++ I +SGL P EY T+ + G+E P+ + T
Sbjct: 476 YAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAM-FGEEASDPVTGQETTLA 534
Query: 1174 LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
LSPP NL + +N + ++W+ T+ I GYRI N G + EV ++
Sbjct: 535 LSPPRNLRI-SNVGSNSARLTWD-PTSRQINGYRIV---YNNADGTEINEVEVDPITTFP 589
Query: 1234 FDNLSPGLEYNVSVYTVKDDKESVPISDTI-IPAVPPPTDLRFTNIGPDTMRVTWAPPPS 1292
L+P EY ++++++ D+ +S P++ VP L + D+ RVTW P S
Sbjct: 590 LKGLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVPAQQYLEIDEVTTDSFRVTW-HPLS 648
Query: 1293 IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRG 1352
D + + PV + E+ + ++ V+ L PGTEY VS+ +V + + +
Sbjct: 649 ADEGLHKLMWIPVYGGK-TEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVT 707
Query: 1353 RQKTGLDS-------------------PTGID---FSDITANSFTVHWIAPRATITGYRI 1390
T LDS TGI D T +S V W + + +R+
Sbjct: 708 AVGTTLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRV 767
Query: 1391 RHHPEHFSGRPRED-----RVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS 1445
+ G P E+ VP S+N++ L L P TEY V++ + E +
Sbjct: 768 TYMTA--QGDPEEEVIGTVMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAPGK 825
Query: 1446 TV-SDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT 1504
T+ S P++L V L I+WD P+ V+ YRI Y P E V +T
Sbjct: 826 TLPSSGPQNLRVSEEWYNRLRITWDPPSSPVKGYRIVYKPVSVPGPTLETFVGADINTIL 885
Query: 1505 ISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP 1564
I+ L G+DY + ++A G S A + + +T + +Q V+ S+ W
Sbjct: 886 ITNLLSGMDYNVKIFASQASGFSDALTGMV----KTLFLGVTNLQAKHVEMTSLCAHW-Q 940
Query: 1565 SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYA--QNPSGESQ 1622
T YRV + T G T GLQP EY +SVY Q G S
Sbjct: 941 VHRHATAYRVVIESLQ-DRQKQESTVGGGTTRHCFYGLQPDSEYKISVYTKLQEIEGPSV 999
Query: 1623 PLVQTAVTNIDRP 1635
+++ + RP
Sbjct: 1000 SIMEKTQSLPTRP 1012
Score = 183 bits (464), Expect = 2e-45
Identities = 170/701 (24%), Positives = 295/701 (42%), Gaps = 71/701 (10%)
Query: 1339 SSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFS 1398
S V EQ TG PT + S++TA SF V+W + YR+ ++P
Sbjct: 336 SRVEEQDREIKASAHAITG--PPTELITSEVTARSFMVNWTHAPGNVEKYRVVYYPTR-G 392
Query: 1399 GRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVV 1457
G+P E V + +S L NL TEY +++ A+ S L G ++T++ + DL +
Sbjct: 393 GKPDEVVVDGTVSSTVLKNLMSLTEYQIAVFAIYAHTASEGLRGTETTLALPMASDLLLY 452
Query: 1458 AATPTSLLISWDA----PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVD 1513
T S+ + WDA + Y +T G G +E + + + +SGL P +
Sbjct: 453 DVTENSMRVKWDAVPGASGYLILYAPLTEGLAGDE---KEMKIGETHTDIELSGLLPNTE 509
Query: 1514 YTITVYAVTGRGDSPASSKPISINYRT-EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGY 1572
YT+TVYA+ G +S P++ T + P +++++V NS + W P+S + GY
Sbjct: 510 YTVTVYAMFGE----EASDPVTGQETTLALSPPRNLRISNVGSNSARLTWDPTSRQINGY 565
Query: 1573 RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN- 1631
R+ N G + T ++GL P EY +++++ G+S+PL T
Sbjct: 566 RIVYN--NADGTEINEVEVDPITTFPLKGLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEE 623
Query: 1632 IDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP----------- 1680
+ + L +V DS ++ W S ++G+H+L P
Sbjct: 624 VPAQQYLEIDEVTTDSFRVTWHP------------LSADEGLHKLMWIPVYGGKTEEVVL 671
Query: 1681 DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAI------PAPTDLKFTQVT 1734
E+D+ ++GL PG+EY VS++A+ DD ++ T + PA T + T VT
Sbjct: 672 KEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVPTTSVT 731
Query: 1735 P----------------TSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEIN--LAPDS-S 1775
+SL +W + + +RV + + I + P S +
Sbjct: 732 SVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMTAQGDPEEEVIGTVMVPGSQN 791
Query: 1776 SVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWR 1835
++++ L+ T+Y+V+V + TL + S P+ RV++ + I+W
Sbjct: 792 NLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAPGKTLPS-SGPQNLRVSEEWYNRLRITWD 850
Query: 1836 TKTETITGFQVDAVPANGQTPIQRT-IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP 1894
+ + G+++ P + P T + D+ + IT L G DY + ++ + S
Sbjct: 851 PPSSPVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQASGFSDA 910
Query: 1895 VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPG 1954
+ T +NL+ SL WQ R T Y + E ++ G
Sbjct: 911 LTGMVKTLFLGVTNLQAKHVEMTSLCAHWQVHR-HATAYRVVIESLQDRQKQ-ESTVGGG 968
Query: 1955 VTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP 1995
T GL+P +EY I V + + +KT LP
Sbjct: 969 TTRHCFYGLQPDSEYKISVYTKLQEIEGPSVSIMEKTQSLP 1009
Score = 175 bits (443), Expect = 5e-43
Identities = 231/983 (23%), Positives = 388/983 (39%), Gaps = 120/983 (12%)
Query: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
V P L++ ++ + I W P GY++ V P + G+ Q + T A + G
Sbjct: 30 VAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTS-GGKTNQLNLQNTATKAIIQG 88
Query: 967 LSPGVTYYFKVFAVSHGRESKPLTAQ----------------------QTTKLDAPTNLQ 1004
L P Y ++ A + +ESKP Q ++ +P ++
Sbjct: 89 LMPDQNYTVQIIAYNKDKESKPAQGQFRIKDLEKRKDPKPRVKVVDRGNGSRPSSPEEVK 148
Query: 1005 FVNET----DSTVLV--RWTPPRAQ-----------ITGYRLTVGLTRRGQPRQYNVGPS 1047
FV +T D +LV W+ R +T + + TR G QY+ P
Sbjct: 149 FVCQTPAIADIVILVDGSWSIGRFNFRLVRHFLENLVTAFDVGSEKTRIGL-AQYSGDPR 207
Query: 1048 VSKY------------PLRNLQPASEYTVSLVAIK---GNQESPKA---TGV------FT 1083
+ + +RNL T++ +A+ N P+A TGV T
Sbjct: 208 IEWHLNAFSTKDEVIEAVRNLPYKGGNTLTGLALNYIFENSFKPEAGSRTGVSKIGILIT 267
Query: 1084 TLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGS-----I 1138
+ I P + + E+ + + F +GV+ + E +E+ S+ S +
Sbjct: 268 DGKSQDDIIPPSRNLRESGVEL---------FAIGVKNADVNEL-QEIASEPDSTHVYNV 317
Query: 1139 VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
L V T + +E+D I PPT L + + V+W +
Sbjct: 318 AEFDLMHTVVESLTRTLCSRVEEQDREIKASAHAITGPPTEL-ITSEVTARSFMVNWTHA 376
Query: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
++ YR+ PT G G E VV SS NL EY ++V+ + S
Sbjct: 377 -PGNVEKYRVVYYPTRG--GKPDEVVVDGTVSSTVLKNLMSLTEYQIAVFAIYAHTASEG 433
Query: 1259 ISDT-IIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN--EEDVAELS 1315
+ T A+P +DL ++ ++MRV W P + +L+ Y+P+ D E+
Sbjct: 434 LRGTETTLALPMASDLLLYDVTENSMRVKWDAVPG--ASGYLILYAPLTEGLAGDEKEMK 491
Query: 1316 ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANSF 1374
I + + L+ LLP TEY V+V +++ + S P+ G++ T L P + S++ +NS
Sbjct: 492 IGETHTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQETTLALSPPRNLRISNVGSNSA 551
Query: 1375 TVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR 1434
+ W I GYRI ++ + G + + L LTP TEY ++I ++
Sbjct: 552 RLTWDPTSRQINGYRIVYN--NADGTEINEVEVDPITTFPLKGLTPLTEYTIAIFSIYDE 609
Query: 1435 EESPLLIGQQSTVSDVPRD--LEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQ 1492
+S L G T +VP LE+ T S ++W + +++ + G +
Sbjct: 610 GQSEPLTG-VFTTEEVPAQQYLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGGK-TE 667
Query: 1493 EFTVPGSKSTATISGLKPGVDYTITVYAVTGRG-------------DSPASSKPISINYR 1539
E + + + I GL+PG +Y +++ AV G DS + +I
Sbjct: 668 EVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVPT 727
Query: 1540 TEIDKPSQ-----MQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTK---TKTAG 1591
T + Q + V D +S+ VKW S S V +RVT G + T
Sbjct: 728 TSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMTAQGDPEEEVIGTVMVP 787
Query: 1592 PDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-NIDRPKGLAFTDVDVDSIKI 1650
Q + ++ L P EY V+V GE + T P+ L ++ + ++I
Sbjct: 788 GSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAPGKTLPSSGPQNLRVSEEWYNRLRI 847
Query: 1651 AWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDME 1710
W+ P V YR+ Y L + +T + L G +Y V + A
Sbjct: 848 TWDPPSSPVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQASGF 907
Query: 1711 SQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1770
S L G T T+L+ V TSL A W + T YRV V + +E +
Sbjct: 908 SDALTGMVKTLFLGVTNLQAKHVEMTSLCAHW-QVHRHATAYRV-VIESLQDRQKQESTV 965
Query: 1771 APDSSSVVVSGLMVATKYEVSVY 1793
++ GL ++Y++SVY
Sbjct: 966 GGGTTRHCFYGLQPDSEYKISVY 988
Score = 160 bits (404), Expect = 2e-38
Identities = 156/663 (23%), Positives = 281/663 (42%), Gaps = 54/663 (8%)
Query: 729 TEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIV 788
+E+TA SF+V+W A V +RV Y G +P + + T +S + +L+ +Y +
Sbjct: 362 SEVTARSFMVNWTHAPGNVEKYRVVY-YPTRGGKPDEVVVDGTVSSTVLKNLMSLTEYQI 420
Query: 789 NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPS 848
V+ I + T T A D + V + S+ V+W +GY I+Y+P
Sbjct: 421 AVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPG-ASGYLILYAPL 479
Query: 849 VE---GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSD 905
E G E+ + ET + LS L P +Y +T+YA+ + S PV Q+ T
Sbjct: 480 TEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQETTL------ 533
Query: 906 TVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVT 965
+ PR+L+ V + W P + GYR ++ N G + + T +
Sbjct: 534 ALSPPRNLRISNVGSNSARLTWDPTSRQINGYR--IVYNNADGTEINEVEVDPITTFPLK 591
Query: 966 GLSPGVTYYFKVFAVSHGRESKPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQI 1024
GL+P Y +F++ +S+PLT TT ++ A L+ T + V W P A
Sbjct: 592 GLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVPAQQYLEIDEVTTDSFRVTWHPLSADE 651
Query: 1025 TGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAI-KGNQESPKATGVFT 1083
++L G+ + + + + L+P +EY VSL+A+ ES T V T
Sbjct: 652 GLHKLMWIPVYGGKTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGT 711
Query: 1084 TL-----QPGSSIPPYNT---------------EVTETTIVITW--TPAPRIGFKLGVRP 1121
TL +P ++I P + + T +++ + W + + F++
Sbjct: 712 TLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMT 771
Query: 1122 SQGGEAPRE-------VTSDSGSIVVSGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTP 1173
+QG P E V ++++ L P EY T+ + DG+ K + P
Sbjct: 772 AQGD--PEEEVIGTVMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAPGKTL-P 828
Query: 1174 LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
S P NL + + L ++W+ ++P + GYRI P + G +LE V AD ++
Sbjct: 829 SSGPQNLRV-SEEWYNRLRITWDPPSSP-VKGYRIVYKPVS-VPGPTLETFVGADINTIL 885
Query: 1234 FDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSI 1293
NL G++YNV ++ + S ++ + T+L+ ++ ++ W
Sbjct: 886 ITNLLSGMDYNVKIFASQASGFSDALTGMVKTLFLGVTNLQAKHVEMTSLCAHWQVHRHA 945
Query: 1294 DLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR 1353
++ + ++ E ++ L P +EY +SV + ++ E +
Sbjct: 946 TAYRVVIESLQDRQKQ---ESTVGGGTTRHCFYGLQPDSEYKISVYTKLQEIEGPSVSIM 1002
Query: 1354 QKT 1356
+KT
Sbjct: 1003 EKT 1005
Score = 100 bits (248), Expect = 2e-20
Identities = 130/581 (22%), Positives = 232/581 (39%), Gaps = 53/581 (9%)
Query: 624 NSHPIQWNAPQPSHISKYILRWRP--KNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQL 681
NS ++W+A + S Y++ + P + G KE I + GL P Y
Sbjct: 457 NSMRVKWDAVPGA--SGYLILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYT--- 511
Query: 682 ISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV 741
VT + S PVT T +P L ++ + ++S ++W
Sbjct: 512 ----------VTVYAMFGEEASDPVTGQETTLALSPPRNL-----RISNVGSNSARLTWD 556
Query: 742 SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSL 801
S ++G+R+ Y + +G E +++ T+ + L P +Y + ++ I ++G+
Sbjct: 557 PTSRQINGYRIVYN-NADGTEINEVEV-DPITTFPLKGLTPLTEYTIAIFSIYDEGQSEP 614
Query: 802 ILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPET 861
+ T A +D+V S V W A +++++ P G + E+ L E
Sbjct: 615 LTGVFTTEEVPAQQYLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGGKTEEVVLKEE 674
Query: 862 ANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETT-----GTPRSDTVPSP------ 910
+S + L+PG +Y +++ AV ++ + VV TT P + VP+
Sbjct: 675 QDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVPTTSVTSVF 734
Query: 911 ----RDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEH----GQRLPISRNTFA 962
R+L + T + + W +S V +RV + E +P S+N
Sbjct: 735 QTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMTAQGDPEEEVIGTVMVPGSQNNLL 794
Query: 963 EVTGLSPGVTYYFKVFAVSHGRESKPLTAQ-QTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
+ L P Y V + E ++A +T P NL+ E + + + W PP
Sbjct: 795 -LKPLLPDTEYKVTVTPIYTDGEGVSVSAPGKTLPSSGPQNLRVSEEWYNRLRITWDPPS 853
Query: 1022 AQITGYRLTV-GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
+ + GYR+ ++ G + VG ++ + NL +Y V + A + + S TG
Sbjct: 854 SPVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQASGFSDALTG 913
Query: 1081 VFTTLQPG-SSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSI- 1138
+ TL G +++ + E+ T++ W V S +E T G+
Sbjct: 914 MVKTLFLGVTNLQAKHVEM--TSLCAHWQVHRHATAYRVVIESLQDRQKQESTVGGGTTR 971
Query: 1139 -VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPT 1178
GL P E Y I V QE + P V+ + S PT
Sbjct: 972 HCFYGLQPDSE--YKISVYTKLQEIEGPSVSIMEKTQSLPT 1010
Score = 53.1 bits (126), Expect = 3e-06
Identities = 31/106 (29%), Positives = 51/106 (48%), Gaps = 4/106 (3%)
Query: 1722 IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSG 1781
+ PT L++ ++ S+ W P + GY++ VTP G ++NL ++ ++ G
Sbjct: 30 VAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSG-GKTNQLNLQNTATKAIIQG 88
Query: 1782 LMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPPR-RARVTD 1824
LM Y V + A S+PAQG + LE P+ R +V D
Sbjct: 89 LMPDQNYTVQIIAYNKDKESKPAQGQFRIKDLEKRKDPKPRVKVVD 134
Score = 50.1 bits (118), Expect = 3e-05
Identities = 21/70 (30%), Positives = 36/70 (51%)
Query: 822 VDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIY 881
+ SI + W P+ GY+++ +P+ G + +LNL TA + L P Y + I
Sbjct: 41 ISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQLNLQNTATKAIIQGLMPDQNYTVQII 100
Query: 882 AVEENQESTP 891
A +++ES P
Sbjct: 101 AYNKDKESKP 110
Score = 48.1 bits (113), Expect = 1e-04
Identities = 33/125 (26%), Positives = 59/125 (47%), Gaps = 8/125 (6%)
Query: 1906 PSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEP 1965
P+ LR+ + +S+ +SW+ PR + GY + P S + + T+A I GL P
Sbjct: 33 PTRLRYNVISHDSIQISWKAPRGKFGGYKLLVT-PTSGGKTNQLNLQNTATKAIIQGLMP 91
Query: 1966 GTEYTIYVIALKNNQKSEPLIGR-------KKTDELPQLVTLPHPNLHGPEILDVPSTVQ 2018
YT+ +IA +++S+P G+ K+ D P++ + N P + V
Sbjct: 92 DQNYTVQIIAYNKDKESKPAQGQFRIKDLEKRKDPKPRVKVVDRGNGSRPSSPEEVKFVC 151
Query: 2019 KTPFV 2023
+TP +
Sbjct: 152 QTPAI 156
Score = 45.8 bits (107), Expect = 5e-04
Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 1/83 (1%)
Query: 1541 EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1600
++ P++++ + +SI + W GY++ TP +G G T T+ I+
Sbjct: 29 QVAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSG-GKTNQLNLQNTATKAIIQ 87
Query: 1601 GLQPTVEYVVSVYAQNPSGESQP 1623
GL P Y V + A N ES+P
Sbjct: 88 GLMPDQNYTVQIIAYNKDKESKP 110
Score = 41.6 bits (96), Expect = 0.009
Identities = 21/81 (25%), Positives = 35/81 (43%)
Query: 1814 VSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGL 1873
V+PP R R + +I ISW+ G+++ P +G Q ++ I GL
Sbjct: 30 VAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQLNLQNTATKAIIQGL 89
Query: 1874 QPGTDYKIYLYTLNDNARSSP 1894
P +Y + + N + S P
Sbjct: 90 MPDQNYTVQIIAYNKDKESKP 110
Score = 32.3 bits (72), Expect = 5.6
Identities = 31/123 (25%), Positives = 52/123 (42%), Gaps = 11/123 (8%)
Query: 731 ITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNV 790
I+ S +SW + G+++ + G Q L+L +TAT I L+P + Y V +
Sbjct: 41 ISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQ-LNLQNTATKAIIQGLMPDQNYTVQI 99
Query: 791 YQISEDGEQSLILSTSQTTAPD----APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYS 846
++D E + Q D P P V VD + SRP +P + +
Sbjct: 100 IAYNKDKESK--PAQGQFRIKDLEKRKDPKPRVKVVDRGN----GSRPSSPEEVKFVCQT 153
Query: 847 PSV 849
P++
Sbjct: 154 PAI 156
>gi|222352127 sidekick 2 [Homo sapiens]
Length = 2172
Score = 164 bits (416), Expect = 7e-40
Identities = 278/1176 (23%), Positives = 459/1176 (39%), Gaps = 172/1176 (14%)
Query: 923 VTIMWTPP---ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA 979
+ + WT P S + Y +++ N P + T V GL P +Y F++ A
Sbjct: 608 INLTWTKPFDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCA 667
Query: 980 VSH------GRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQ-----ITGYR 1028
V+ ++++ ++ + P N+ T+ +++++W PP + GY
Sbjct: 668 VNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYI 727
Query: 1029 LTVGLTRRGQPRQYN----VGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT- 1083
+ L G P Y V+ L +L + Y + + A GV++
Sbjct: 728 IRYCLA--GLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNS-----AGLGVYSS 780
Query: 1084 -----TLQPGSSIPPYNTEV---TETTIVITWT-PAPRI------GFKLGVRPSQGGEAP 1128
TLQ ++PP N TTI TW P+P+ G+KL + E
Sbjct: 781 KVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEV 840
Query: 1129 REVTS-----DSGSI-VVSGLTPGVEYVYTIQVLR---DGQERDAPIVNKVVTPLSPPTN 1179
VT+ DS + VSGL EY ++ DG +V P +
Sbjct: 841 TMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGH 900
Query: 1180 LHLEANPDTGVLTVSWERSTTPD--ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNL 1237
L DT L VSW+ + +TGYRI+ N + V H + T +
Sbjct: 901 LSFSEILDTS-LKVSWQEPGEKNGILTGYRISWEEYN----RTNTRVTHY-LPNVTLEYR 954
Query: 1238 SPGLE----YNVSVYTVKDDKESVPISDTIIPAVPP-----PTDLRFTNIGPDTMRVTWA 1288
GL Y + V + + + TI VPP PT+L +NIGP ++ + +
Sbjct: 955 VTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFR 1014
Query: 1289 P--PPSIDLTNFLV--RYSPVKNEED---VAELSISPSDNAVVLTNLLPGTEYVVSVSSV 1341
P ++ +LV + V E+ + +LS P ++ + +L P T Y + V
Sbjct: 1015 PGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQV 1074
Query: 1342 YEQHESTPLRGRQKTGL------DSPTGIDFSDITANSFTVHWIA-------PRATITGY 1388
S P + +K +P + + S + W+ GY
Sbjct: 1075 NIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGY 1134
Query: 1389 RIRHHPEHFSGRPR----EDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESP---LLI 1441
+I++ G+ +DRV T+ +L TEY V + A N P ++
Sbjct: 1135 KIKYSRSDGHGKTLSHVVQDRV---ERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVV 1191
Query: 1442 GQ--QSTVSDVPRDLEVVAATPTSLLISW-DAPAVT----VRYYRITYGETGGNSPVQEF 1494
G+ +S S P ++ +A T +S+L+ W + P V Y++ Y E ++ + +
Sbjct: 1192 GRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFW 1251
Query: 1495 TVPGSKS-TATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ-MQVTD 1552
V G+ S +A ++GL V Y + V A T GD S PI ++ P + +
Sbjct: 1252 LVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPE 1311
Query: 1553 VQDNSISVKWLPSSSP---VTGYRVTTTPKNGPGPTKT-KTAGPDQTEMTIEGLQPTVEY 1608
V+ S+ + W P ++P + Y++T T T + P + T GL+P Y
Sbjct: 1312 VRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVY 1371
Query: 1609 VVSVYAQNPSGESQPLVQTAVTNI--DRPKG-----LAFTDVDVDSIKIAWESPQGQVSR 1661
+ + AQ G + VT DRP+ + DV S+ ++WE +S
Sbjct: 1372 LFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSP 1431
Query: 1662 ---YRVTYSSPEDGIHELFPAPDGEEDTAEL-QGLRPGSEYTVSVVALHD------DMES 1711
Y + G L A ++ + L+P + Y V A +D ES
Sbjct: 1432 VRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEES 1491
Query: 1712 QPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP-----NVQLTGYRVR----------- 1755
+ L Q+ APT L T T TS+ +W PP N L G+R+R
Sbjct: 1492 ESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRG 1551
Query: 1756 ----------VTPKEKTGPMKEINLA-PDSSSVVVSGLMVATKYEV--SVY-ALKDTLTS 1801
T E T NL+ P + + L +YE+ SVY A+ + +S
Sbjct: 1552 FTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSS 1611
Query: 1802 RPAQGVVTTLENVSPPRRARVTDATETTITISWR-----TKTETITGFQVDAVPANGQTP 1856
P + V + PR V AT T + ++W ++ I G+++ A
Sbjct: 1612 PPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNL 1671
Query: 1857 IQR--TIKPDVRSYTITGLQPGTDYKIYLYTLN---DNARSSPVVIDASTAI-DAPSNLR 1910
+R T+ S + L T Y + + N D RS+P A APS+++
Sbjct: 1672 TERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVK 1731
Query: 1911 FLATTPNSLLVSWQPPR---ARITGYIIKYEKPGSP 1943
F T S+ VSW+ P+ + GY + YE P SP
Sbjct: 1732 FSELTTTSVNVSWEAPQFPNGILEGYRLVYE-PCSP 1766
Score = 156 bits (395), Expect = 2e-37
Identities = 286/1279 (22%), Positives = 473/1279 (36%), Gaps = 170/1279 (13%)
Query: 772 ATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV-----DDTS 826
ATSV + L+P R Y + +++ G+ T + + P+ PP V + S
Sbjct: 647 ATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQS 706
Query: 827 IVVRWSRP-----QAPITGYRIVY--SPSVEGSSTELNLPETANSVTLSDLQPGVQYNIT 879
I+++W P + GY I Y + G + N++ L DL Y I
Sbjct: 707 IMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIE 766
Query: 880 IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAV----- 934
+ A N V + T T + P ++ + W P
Sbjct: 767 VAAY--NSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGIN 824
Query: 935 TGYRVDVIPVNLPGEHGQRLPISRNTFAE------VTGLSPGVTYYFKVFAVS---HGRE 985
GY+ +I E + +R F + V+GL Y+ V + G
Sbjct: 825 QGYK--LIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPR 882
Query: 986 SKPLTAQQTTKLDAPT-NLQFVNETDSTVLVRWTPPRAQ---ITGYRLTVGLTRRGQPRQ 1041
S P + + P +L F D+++ V W P + +TGYR++ R R
Sbjct: 883 STPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRV 942
Query: 1042 YNVGPSVS-KYPLRNLQPASEYTVSLVAIKG-NQESPKATGVFTTLQPGSSIPPYNTEVT 1099
+ P+V+ +Y + L + YT+ + A+ Q A+ + + + P PP N ++
Sbjct: 943 THYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGIS 1002
Query: 1100 E----------------TTIVITWTPAPRIGFKLGVRPSQGGEAPREVTS--DSGSIVVS 1141
T + W ++G V + ++++ D+ S+ V
Sbjct: 1003 NIGPRSVTLQFRPGYDGKTSISRWLVEAQVGV---VGEGEEWLLIHQLSNEPDARSMEVP 1059
Query: 1142 GLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSP----PTNLHLEANPDTGVLTVSW- 1195
L P Y + + QV G + K+ T +P P N+ L +T L + W
Sbjct: 1060 DLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETS-LWLRWM 1118
Query: 1196 -----ERSTTPDITGYRITTTPTNGQQGNSLEEVVH-ADQSSCTFDNLSPGLEYNVSVYT 1249
E + P+ GY+I + ++G G +L VV + T ++L EY V V
Sbjct: 1119 PLPEMEYNGNPESVGYKIKYSRSDG-HGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQA 1177
Query: 1250 VKDDKESVPISDTII----PAVPP--PTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYS 1303
+ S P S T++ +VP PT++ +M V W+ P D ++ Y
Sbjct: 1178 F-NAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYK 1236
Query: 1304 PVKNEEDVAE-----LSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP-----LRGR 1353
+ E+D L S + LT L Y V V + + +P L
Sbjct: 1237 VMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERT 1296
Query: 1354 QKTGLDSPTGIDFSDITANSFTVHW---IAPRATITGYRIRHHPEHFSGRPREDRV-PHS 1409
P GI F ++ S + W AP I Y+I H + V S
Sbjct: 1297 LDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPS 1356
Query: 1410 RNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTVSDVPRDLEVVA---ATPT 1462
T T L P + Y+ I A G L++ + P +V
Sbjct: 1357 ARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRAR 1416
Query: 1463 SLLISWDAPA---VTVRYYRITYGE-TGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
S+L+SW+ + VRYY I E G + +V + S+ + LKP Y V
Sbjct: 1417 SVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRV 1476
Query: 1519 YAVTGRGDSPAS--SKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSP-----VTG 1571
A GDS S S+ ++ + P+ + VT S+ ++W P + + G
Sbjct: 1477 KATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLG 1536
Query: 1572 YRV-------------TTTPKNGPGPTKTKTAG---------PDQTEMTIEGLQPTVEYV 1609
+R+ T N PG T + P T+ ++ L Y
Sbjct: 1537 FRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYE 1596
Query: 1610 V--SVY---AQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESP-----QGQV 1659
+ SVY + PS Q + P+ + + + WE P G +
Sbjct: 1597 IRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDI 1656
Query: 1660 SRYRVTYSSPEDG-----IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH---DDMES 1711
Y++ + + G + LF A E++ +L+ L + Y VSV A + D S
Sbjct: 1657 QGYKIYFWEAQRGNLTERVKTLFLA----ENSVKLKNLTGYTAYMVSVAAFNAAGDGPRS 1712
Query: 1712 QPLIG-TQSTAIPAPTDLKFTQVTPTSLSAQWTP---PNVQLTGYRVRVTP-KEKTGPMK 1766
P G TQ A AP+ +KF+++T TS++ W PN L GYR+ P G K
Sbjct: 1713 TPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSK 1772
Query: 1767 EINLAPDSSS---VVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSP-PRRARV 1822
+ + +S + V L Y + A T V T +P P +
Sbjct: 1773 IVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPI 1832
Query: 1823 TDATETTITISWRTKTE---TITGFQVDAVPAN-GQTPIQ-RTIKPDVRSYTITG--LQP 1875
+ I I W + IT + ++A P++ G I + I +V SYT + L+P
Sbjct: 1833 IVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKP 1892
Query: 1876 GTDYKIYLYTLNDNARSSP 1894
G Y + +ND +P
Sbjct: 1893 GVSYDFRVIAVNDYGFGTP 1911
Score = 136 bits (342), Expect = 3e-31
Identities = 260/1236 (21%), Positives = 460/1236 (37%), Gaps = 179/1236 (14%)
Query: 594 IGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQ-------------WNAPQP--SHI 638
IG + C+ + + S + + + P P HP+ W P S +
Sbjct: 564 IGTYTCRVISAGGNDSRSAHLRVRQLPHAPE-HPVATLSTVERRAINLTWTKPFDGNSPL 622
Query: 639 SKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFT 698
+YIL N+ A++ S T+KGL P Y+ +L ++ G + F
Sbjct: 623 IRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQ---FSKD 679
Query: 699 TTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDT-----VSGFRVE 753
T S P T P ++A+ T S ++ W ++ + G+ +
Sbjct: 680 TERVSLPEEP-----PTAPPQNVIASGR-----TNQSIMIQWQPPPESHQNGILKGYIIR 729
Query: 754 YELSEEGDEPQYLDL-PSTATSVNIPDLLPGRKYIVNVYQISEDG---EQSLILSTSQTT 809
Y L+ Q+ ++ + ++ + DL+ Y + V + G S + +
Sbjct: 730 YCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQG 789
Query: 810 APDAPP-DPTVDQVDDTSIVVRWSRPQAPI-----TGYRIV-YSPSVEGSSTEL----NL 858
P PP + + + T+I W+ P GY+++ + P E T + N
Sbjct: 790 VPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNF 849
Query: 859 PETANSVTLSDLQPGVQYNITIYAVE---ENQESTPVVIQQETTGTPRSDTVPSP-RDLQ 914
++ + +S L+ +Y ++ + STP +++ + VP P L
Sbjct: 850 QDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTH-------EDVPGPVGHLS 902
Query: 915 FVEVTDVKVTIMWTPP---ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGV 971
F E+ D + + W P +TGYR+ N + VTGL+
Sbjct: 903 FSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALT 962
Query: 972 TYYFKVFAVSHGRESKPLTAQQTTKL-----DAPTNLQFVNETDSTVLVRWTP---PRAQ 1023
TY +V A++ + + + ++ + PTNL N +V +++ P +
Sbjct: 963 TYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTS 1022
Query: 1024 ITGY--RLTVGLTRRGQP----RQYNVGPSVSKYPLRNLQPASEYTVSL--VAIKGNQES 1075
I+ + VG+ G+ Q + P + +L P + Y+ + V I G
Sbjct: 1023 ISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPP 1082
Query: 1076 PKATGVFTTLQPGSSIPPYNTEV---TETTIVITWTPAPR---------IGFKLGVRPSQ 1123
+ + TLQ + P N + +ET++ + W P P +G+K+ S
Sbjct: 1083 SQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSD 1142
Query: 1124 G-GEAPREVTSD--SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVV------TPL 1174
G G+ V D + L E Y +QV P VV P
Sbjct: 1143 GHGKTLSHVVQDRVERDYTIEDLEEWTE--YRVQVQAFNAIGSGPWSQTVVGRTRESVPS 1200
Query: 1175 SPPTNLHLEANPDTGVLTVSWERSTTPD----ITGYRITTTPTNGQQGNSLEEVVHADQS 1230
S PTN+ A + +L V W D + GY++ + V
Sbjct: 1201 SGPTNVSALATTSSSML-VRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSR 1259
Query: 1231 SCTFDNLSPGLEYNVSVYT---VKDDKES-VPISDTIIPAVP-PPTDLRFTNIGPDTMRV 1285
S L + Y V V + D S PI + + VP PP + F + ++R+
Sbjct: 1260 SAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRL 1319
Query: 1286 TWAPP--PSIDLTNFLVRYSPVKNEEDVAELSI-SPSDNAVVLTNLLPGTEYVVSVSSVY 1342
W PP P+ + + + + + A + + +PS T L P + Y+ +++
Sbjct: 1320 IWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQT 1379
Query: 1343 -----EQHESTPLRGRQKTGLDSPTG--IDFSDITANSFTVHWIAPR---ATITGYRIRH 1392
E E+ + ++ P+ + D+ A S + W + + Y I+
Sbjct: 1380 RKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQT 1439
Query: 1393 HPEHFSGR--PREDRVPHSRNSITLTNLTPGTEYVVSIVALNG------REESPLLIGQQ 1444
E SGR V H+ +S + L P T Y + A N EES L Q
Sbjct: 1440 R-ELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQ 1498
Query: 1445 STVSDVPRDLEVVAATPTSLLISWDAPA----------VTVRYYRITY----GET--GGN 1488
+ + P L V T TS+LI W PA +RY + Y G T G N
Sbjct: 1499 AAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGIN 1558
Query: 1489 SP------------VQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS-SKPIS 1535
+P ++ + P S + + L Y I + G+ P+S + +
Sbjct: 1559 NPGATWAELTSMYSMRNLSRP-SLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVF 1617
Query: 1536 INYRTEIDKPSQMQVTDVQDNSISVKWLP-----SSSPVTGYRV-TTTPKNGPGPTKTKT 1589
+ P + V + V W P + + GY++ + G + KT
Sbjct: 1618 VGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKT 1677
Query: 1590 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE---SQPLV-QTAVTNIDRPKGLAFTDVDV 1645
+ + ++ L Y+VSV A N +G+ S P QT P + F+++
Sbjct: 1678 LFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTT 1737
Query: 1646 DSIKIAWESPQ---GQVSRYRVTYS--SPEDGIHEL 1676
S+ ++WE+PQ G + YR+ Y SP DG+ ++
Sbjct: 1738 TSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKI 1773
Score = 123 bits (309), Expect = 2e-27
Identities = 273/1262 (21%), Positives = 481/1262 (38%), Gaps = 173/1262 (13%)
Query: 606 PSSSGPVEVFITETPSQPNSHPIQWNAPQPSH----ISKYILRWRPKN-SVGRWKEATIP 660
P ++ P V + +Q S IQW P SH + YI+R+ VG +
Sbjct: 689 PPTAPPQNVIASGRTNQ--SIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITD 746
Query: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
+N+ ++ L +++ I + Y S V S+ VT T P
Sbjct: 747 ADVNNLLLEDL---IIWTNYEIEVAAYN------------SAGLGVYSSKVTEWTLQGVP 791
Query: 721 LVATSESVTEITASSFV-VSWVSASDT-VSGFRVEYEL-----SEEGDEPQYLDLPSTAT 773
V E T S+ + +W + S ++G Y+L +E + P+
Sbjct: 792 TVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQD 851
Query: 774 SVNI---PDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDP---TVDQVDDTSI 827
S+++ L +Y +V + G+ T D P + ++ DTS+
Sbjct: 852 SIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSL 911
Query: 828 VVRWSRP---QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVE 884
V W P +TGYRI + E + T + +VTL G+ +T Y +E
Sbjct: 912 KVSWQEPGEKNGILTGYRISWE---EYNRTNTRVTHYLPNVTLEYRVTGLTA-LTTYTIE 967
Query: 885 ----ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP---ESAVTGY 937
++ V ++G P P P +L + VT+ + P +++++ +
Sbjct: 968 VAAMTSKGQGQVSASTISSGVPPELPGP-PTNLGISNIGPRSVTLQFRPGYDGKTSISRW 1026
Query: 938 RVDVIPVNLPGEHGQRLPISRNT------FAEVTGLSPGVTYYFK---VFAVSHGRESKP 988
V+ V + GE + L I + + EV L+P Y F+ V V S+P
Sbjct: 1027 LVEA-QVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQP 1085
Query: 989 LTAQQTTKLD---APTNLQFVNETDSTVLVRWTP-PRAQITGYRLTVGLTRR-------G 1037
QT + AP N+ +++++ +RW P P + G +VG + G
Sbjct: 1086 SRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHG 1145
Query: 1038 QPRQYNVGPSVSK-YPLRNLQPASEYTVSLVAIKGNQESP-KATGVFTTLQPGSSIPPYN 1095
+ + V V + Y + +L+ +EY V + A P T V T + S P N
Sbjct: 1146 KTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTN 1205
Query: 1096 TEVTETT---IVITWTPAPR-------IGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTP 1145
TT +++ W+ P +G+K+ + PR + S + LT
Sbjct: 1206 VSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTG 1265
Query: 1146 GVEYV-YTIQVLR-----DGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199
+YV Y +QVL DG PI+ + + + P L T + + W+
Sbjct: 1266 LGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPA 1325
Query: 1200 TPD--ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY--NVSVYTVKDDKE 1255
P+ I Y+IT + EV+ T L P Y ++ T K E
Sbjct: 1326 APNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGE 1385
Query: 1256 S-----VPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEE- 1309
+ V P P ++ ++ ++ ++W P S L+ VRY ++ E
Sbjct: 1386 AAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPG-SDGLSP--VRYYTIQTREL 1442
Query: 1310 -----DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYE------QHESTPLRGRQKTGL 1358
+ S+S + ++ ++ L P T Y V + + ES L Q
Sbjct: 1443 PSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPD 1502
Query: 1359 DSPTGIDFSDITANSFTVHWIAP-----RATITGYRIRHHPEHFSGRP----REDRVPH- 1408
++PT + + T S + W P + G+RIR+ + G R P
Sbjct: 1503 EAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGA 1562
Query: 1409 --------------SRNSIT---LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV- 1450
SR S+T L NL Y + + N E P Q+ V +
Sbjct: 1563 TWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAV 1622
Query: 1451 ----PRDLEVVAATPTSLLISWDAPAVT-----VRYYRITYGETG-GNSPVQEFTVPGSK 1500
PR++ V AT T L ++W+ P + ++ Y+I + E GN + T+ ++
Sbjct: 1623 PTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAE 1682
Query: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1560
++ + L Y ++V A GD P S+ + PS ++ +++ S++V
Sbjct: 1683 NSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNV 1742
Query: 1561 KWLPSSSP---VTGYRVTTTPKNG-PGPTKTKTA---GPDQTEMTIEGLQPTVEYVVSVY 1613
W P + GYR+ P + G +K T G + ++ L V Y +
Sbjct: 1743 SWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIR 1802
Query: 1614 AQNPSGESQPLVQTAVTN-----IDRPKGLAFTDVDVDSIKIAWESP---QGQVSRYRVT 1665
A+ + P ++ VT P G+ +I I W S +G ++RY +
Sbjct: 1803 AKTFT--YGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIE 1860
Query: 1666 YSSPEDGIHELFPAPDGEED---TAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAI 1722
++G+ ++ +E T + L+PG Y V+A++D P + S ++
Sbjct: 1861 ARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTP--SSPSQSV 1918
Query: 1723 PA 1724
PA
Sbjct: 1919 PA 1920
Score = 76.6 bits (187), Expect = 3e-13
Identities = 102/446 (22%), Positives = 182/446 (40%), Gaps = 71/446 (15%)
Query: 600 QPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATI 659
+ L T ++ ++ TP S I+W P I+ +L +R R++E
Sbjct: 1492 ESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRI-----RYRELLY 1546
Query: 660 PGHLNSYTIKGLK-PGVVYEG--QLISIQQYGHQEVTRFDFTTTST-------------- 702
G L +T++G+ PG + + S++ +T+++ +
Sbjct: 1547 EG-LRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAV 1605
Query: 703 ----STPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV-----SASDTVSGFRVE 753
S+P GE P + + V TA+ V+W S + + G+++
Sbjct: 1606 GEGPSSP-PQEVFVGEAVPTA--APRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIY 1662
Query: 754 YELSEEGDEPQYLDLPSTA-TSVNIPDLLPGRKYIVNV--YQISEDGEQSL-ILSTSQTT 809
+ ++ G+ + + A SV + +L Y+V+V + + DG +S +Q
Sbjct: 1663 FWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQA 1722
Query: 810 APDAPPDPTVDQVDDTSIVVRWSRPQAP---ITGYRIVYSPS--VEGSSTELNLPETANS 864
AP AP ++ TS+ V W PQ P + GYR+VY P V+G S + + NS
Sbjct: 1723 APSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNS 1782
Query: 865 ---VTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDV 921
+ + DL GV Y I A + P + TTG + P P + +
Sbjct: 1783 PLWLKVKDLAEGVTYRFRIRA--KTFTYGPEIEANVTTGP--GEGAPGPPGVPIIVRYSS 1838
Query: 922 KVTIMWT---PPESAVTGYRV----------DVIPVNLPGEHGQRLPISRNTFAEVTGLS 968
+ I W+ P + +T Y + D++ ++P E +S TF+ + L
Sbjct: 1839 AIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKE------VSSYTFS-MDILK 1891
Query: 969 PGVTYYFKVFAVSHGRESKPLTAQQT 994
PGV+Y F+V AV+ P + Q+
Sbjct: 1892 PGVSYDFRVIAVNDYGFGTPSSPSQS 1917
Score = 74.7 bits (182), Expect = 1e-12
Identities = 112/450 (24%), Positives = 173/450 (38%), Gaps = 59/450 (13%)
Query: 1643 VDVDSIKIAWESP---QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYT 1699
V+ +I + W P + RY + S L + D + + ++GL P Y
Sbjct: 603 VERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQ 662
Query: 1700 VSVVALHDDMESQPLIGTQSTAIPA------PTDLKFTQVTPTSLSAQWTPP-----NVQ 1748
+ A++D + Q T+ ++P P ++ + T S+ QW PP N
Sbjct: 663 FRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGI 722
Query: 1749 LTGYRVRVTPKEKTGPMKEINLAP-DSSSVVVSGLMVATKYEVSVYALKDT--------L 1799
L GY +R + N+ D +++++ L++ T YE+ V A +
Sbjct: 723 LKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKV 782
Query: 1800 TSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETIT-----GFQVDA-VPANG 1853
T QGV T PP TTI +W + G+++ A P
Sbjct: 783 TEWTLQGVPTV-----PPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQE 837
Query: 1854 QTPIQRTIKPDVRSYT----ITGLQPGTDY---KIYLYTLNDNARSSPVVIDASTAIDAP 1906
+ T +P+ + ++GL+ T+Y + T D RS+P ++ + P
Sbjct: 838 EEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGP 897
Query: 1907 -SNLRFLATTPNSLLVSWQPPRAR---ITGYIIKYEKPGSPPREVVPRPRPGVT-EATIT 1961
+L F SL VSWQ P + +TGY I +E+ V P VT E +T
Sbjct: 898 VGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVT-HYLPNVTLEYRVT 956
Query: 1962 GLEPGTEYTIYVIALKN---NQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQ 2018
GL T YTI V A+ + Q S I ELP P NL I T+Q
Sbjct: 957 GLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPG----PPTNLGISNIGPRSVTLQ 1012
Query: 2019 KTPFVTHPGYDTGNGIQLPGTSGQQPSVGQ 2048
PGYD I Q VG+
Sbjct: 1013 -----FRPGYDGKTSISRWLVEAQVGVVGE 1037
Score = 70.9 bits (172), Expect = 1e-11
Identities = 111/557 (19%), Positives = 213/557 (38%), Gaps = 47/557 (8%)
Query: 1413 ITLTNLTPGTEYVVSIVALNGREESP--LLIGQQSTVSDVPRDLEVVAATPTSLL--ISW 1468
I+ T+++ Y G +E+ L++ ++ ++ P+D V+ T S++ ++
Sbjct: 462 ISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTH 521
Query: 1469 DAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSP 1528
D P VT+RY G T G + + S IS G T T ++ G+
Sbjct: 522 D-PRVTIRYIWEKDGATLGTESHPRIRLDRNGSLH-ISQTWSGDIGTYTCRVISAGGNDS 579
Query: 1529 ASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW---LPSSSPVTGYRVTTTPKNGPGPT 1585
S+ + + + ++ V+ +I++ W +SP+ Y + + N P
Sbjct: 580 RSAH-LRVRQLPHAPEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTV 638
Query: 1586 KTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR------PKGLA 1639
+ P T +T++GL P Y + A N G+ Q T ++ P+ +
Sbjct: 639 LLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVI 698
Query: 1640 FTDVDVDSIKIAWESP-----QGQVSRYRVTYSSPEDGI-HELFPAPDGEEDTAELQGLR 1693
+ SI I W+ P G + Y + Y + ++ D + + L+ L
Sbjct: 699 ASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLI 758
Query: 1694 PGSEYTVSVVALHD---DMESQPLIGTQSTAIPA--PTDLKFTQVTPTSLSAQWTPPNVQ 1748
+ Y + V A + + S + +P P ++ T++ W P+ Q
Sbjct: 759 IWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQ 818
Query: 1749 L-----TGYRVRVTPKEKTGPMKEINLAPDSSSVV----VSGLMVATKYEVSVYALKDTL 1799
GY++ E+ + + P+ + VSGL T+Y SV
Sbjct: 819 FINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPG 878
Query: 1800 TS-RPAQGVVTTLENV-SPPRRARVTDATETTITISWR---TKTETITGFQVDAVPANGQ 1854
R +V T E+V P ++ +T++ +SW+ K +TG+++ N
Sbjct: 879 DGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRT 938
Query: 1855 TPIQRTIKPDVR-SYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI-----DAPSN 1908
P+V Y +TGL T Y I + + + S+ + P+N
Sbjct: 939 NTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTN 998
Query: 1909 LRFLATTPNSLLVSWQP 1925
L P S+ + ++P
Sbjct: 999 LGISNIGPRSVTLQFRP 1015
Score = 37.7 bits (86), Expect = 0.13
Identities = 38/149 (25%), Positives = 59/149 (39%), Gaps = 20/149 (13%)
Query: 555 CDPVDQCQDSETGTFYQIGDSWEK---------YVHGVRYQCYCYGRGIGEWHCQPLQTY 605
C PVD T W K Y +R + + YG I + T
Sbjct: 1764 CSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEA----NVTTG 1819
Query: 606 PSSSGPVEVFITETPSQPNSHPIQWNAPQPSH--ISKYILRWRPKNSVGRWKEAT--IPG 661
P P + ++ I W++ P I++Y++ RP + G W IP
Sbjct: 1820 PGEGAPGPPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDE-GLWDILIKDIPK 1878
Query: 662 HLNSYTIKG--LKPGVVYEGQLISIQQYG 688
++SYT LKPGV Y+ ++I++ YG
Sbjct: 1879 EVSSYTFSMDILKPGVSYDFRVIAVNDYG 1907
>gi|157952215 protein tyrosine phosphatase, receptor type, B isoform a
[Homo sapiens]
Length = 2215
Score = 164 bits (416), Expect = 7e-40
Identities = 281/1370 (20%), Positives = 531/1370 (38%), Gaps = 122/1370 (8%)
Query: 668 IKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSES 727
++ L+ G +Y ++IS+ + TV +T P P S
Sbjct: 300 LQDLQAGTIYNFRIISLDE---------------------ERTVVLQTDPLPP-ARFGVS 337
Query: 728 VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT--SVNIPDLLPGRK 785
+ T++S V W +S V+ + V+ E + Q + + + + +L G K
Sbjct: 338 KEKTTSTSLHVWWTPSSGKVTSYEVQL-FDENNQKIQGVQIQESTSWNEYTFFNLTAGSK 396
Query: 786 YIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVY 845
Y + + +S G++S + T+ +T P D + S+++ WS + YR++
Sbjct: 397 YNIAITAVS-GGKRSFSVYTNGSTVPSPVKDIGIS-TKANSLLISWSHGSGNVERYRLML 454
Query: 846 SPS---VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTP 902
V G + + A S L PG YN+T+ ++ + +
Sbjct: 455 MDKGILVHGGVVDKH----ATSYAFHGLTPGYLYNLTVMTEAAGLQNYRWKLVRT----- 505
Query: 903 RSDTVPSPRDLQFVEVTD----VKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP-IS 957
+P ++ ++VT+ + + W P V Y + + E P I+
Sbjct: 506 ------APMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWIT 559
Query: 958 RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDS-TVLVR 1016
F E L PG Y V VS G S A T D NL+ N +++V
Sbjct: 560 ETHFKE---LVPGRLYQVTVSCVS-GELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVS 615
Query: 1017 WTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN--LQPASEYTVSLVAIKGNQE 1074
W+PP YR+ + VG ++Y + + L P +Y V ++ GN +
Sbjct: 616 WSPPAGDWEQYRILL-FNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLK 674
Query: 1075 SPKATGVFTTLQPGSSIPPYNTEVTETTIVITW-TP-APRIGFKLGVRPSQGGEAPREVT 1132
+ + T P + + ET++ I W TP A + + + + ++
Sbjct: 675 NSERCQGRTV--PLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIHKSLS 732
Query: 1133 SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLT 1192
D+ + L PG +Y+ T+ + + + + + V + T+LH+ T L
Sbjct: 733 KDAKEFTFTDLVPGRKYMATVTSISGDLKNSSSVKGRTVP--AQVTDLHVANQGMTSSLF 790
Query: 1193 VSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD 1252
+W ++ D+ Y++ N N E + ++ S +F +L G Y+V V TV
Sbjct: 791 TNWTQAQG-DVEFYQVLLIHENVVIKN---ESISSETSRYSFHSLKSGSLYSVVVTTVSG 846
Query: 1253 DKES--VPISDTIIPAVPPPTDLRFTNIGP-DTMRVTWAPPPSIDLTNFLVRYSPVKNEE 1309
S V + +P+ + + N G D + V+W P D+ N+ V S + +
Sbjct: 847 GISSRQVVVEGRTVPS--SVSGVTVNNSGRNDYLSVSWLLAPG-DVDNYEVTLS--HDGK 901
Query: 1310 DVAELSISPSDNAVVLTNLLPGTEYVVSV---SSVYEQHESTPLRGRQKTGLDSPTGIDF 1366
V L I+ S ++L PG Y V++ S YE H + +++T D G+
Sbjct: 902 VVQSLVIAKSVRECSFSSLTPGRLYTVTITTRSGKYENHSFS----QERTVPDKVQGVSV 957
Query: 1367 SDITANSFT-VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYV 1425
S+ + + V W+ Y + ++ + + +P S N L PG Y
Sbjct: 958 SNSARSDYLRVSWVHATGDFDHYEVTIKNKNNFIQTKS--IPKSENECVFVQLVPGRLYS 1015
Query: 1426 VSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRIT--YG 1483
V++ +G+ E+ G T+ + +DL + + L ++W V Y I +
Sbjct: 1016 VTVTTKSGQYEANEQ-GNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFN 1074
Query: 1484 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
+ P F + + + + L PG Y I V ++G A + ++ +
Sbjct: 1075 DMKVFPP---FHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNI 1131
Query: 1544 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
S TD S++V W P V Y V+ + ++T E T L+
Sbjct: 1132 HISPNGATD----SLTVNWTPGGGDVDSYTVSAFRHSQK--VDSQTIPKHVFEHTFHRLE 1185
Query: 1604 PTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYR 1663
+Y + + + + S ++Q V +A S+ ++W+ G RY
Sbjct: 1186 AGEQYQIMIASVSGSLKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYD 1245
Query: 1664 VTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP 1723
+ + E+GI + + + L PG +Y + ++ + + S+ T
Sbjct: 1246 ILLLT-ENGILLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPA 1304
Query: 1724 APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE-INLAPDSSSVVVSGL 1782
A TDL+ T+ + LS +WT +L+ Y + + + G ++E + P S L
Sbjct: 1305 AVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPD--GNLQERAQVDPLVQSFSFQNL 1362
Query: 1783 MVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETIT 1842
+ Y++ + L++ T +VS R + T ++ +W +
Sbjct: 1363 LQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRN--TTDSLWFNWSPASGDFD 1420
Query: 1843 GFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA 1902
+++ NG T + D+ + GL PG Y +++ T + S+ V ++ TA
Sbjct: 1421 FYELILYNPNG-TKKENWKDKDLTEWRFQGLVPGRKYVLWVVT-HSGDLSNKVTAESRTA 1478
Query: 1903 IDAPSNLRFLATTPNSLLVSWQ--PPRARITGYIIKYEKPGSPPREVVPRPRPGVTEAT- 1959
PS + F SL ++W+ P + +++ PR+ + P +
Sbjct: 1479 PSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQW-----LPRDALTVFNPYNNRKSE 1533
Query: 1960 ---ITGLEPGTEYTIYVIALKNNQ---KSEPLIG--RKKTDELPQLVTLP 2001
+ GL PG Y V + + S+P+ G R K D++ L P
Sbjct: 1534 GRIVYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRP 1583
Score = 154 bits (389), Expect = 1e-36
Identities = 268/1271 (21%), Positives = 471/1271 (37%), Gaps = 99/1271 (7%)
Query: 662 HLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPL 721
H SY GL PG +Y L + + + R+ T +P+
Sbjct: 469 HATSYAFHGLTPGYLY--NLTVMTEAAGLQNYRWKLVRT------------------APM 508
Query: 722 VATSESVT-EITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
++ VT + + +S V W V + + LS +G + L T + +L
Sbjct: 509 EVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNI--TLSHKGTIKESRVLAPWITETHFKEL 566
Query: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDD-TSIVVRWSRPQAPIT 839
+PGR Y V V +S GE S T PD + + S+VV WS P
Sbjct: 567 VPGRLYQVTVSCVS--GELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWE 624
Query: 840 GYRI-VYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898
YRI +++ SV + + ET + + L PG QY + + N +++
Sbjct: 625 QYRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLKNSE------- 677
Query: 899 TGTPRSDTVP-SPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS 957
+ TVP + L+ + ++IMW P + Y + + +L H + L
Sbjct: 678 --RCQGRTVPLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIH-KSLSKD 734
Query: 958 RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE-TDSTVLVR 1016
F T L PG Y V ++S ++ +T T+L N+ S++
Sbjct: 735 AKEFT-FTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPAQV-TDLHVANQGMTSSLFTN 792
Query: 1017 WTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
WT + + Y++ + + + ++ S+Y +L+ S Y+V + + G S
Sbjct: 793 WTQAQGDVEFYQVLL-IHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSR 851
Query: 1077 KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPRE--VTSD 1134
+ T+ S N + ++W AP V S G+ + +
Sbjct: 852 QVVVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAKS 911
Query: 1135 SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVS 1194
S LTPG Y TI E + + V ++ A D L VS
Sbjct: 912 VRECSFSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSD--YLRVS 969
Query: 1195 WERSTTPDITGYRITTTPTNGQQGNSLE-EVVHADQSSCTFDNLSPGLEYNVSVYTVKDD 1253
W + T D Y +T N N ++ + + ++ C F L PG Y+V+V T
Sbjct: 970 WVHA-TGDFDHYEVTIKNKN----NFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQ 1024
Query: 1254 KESVPISD-TIIPAVPPPTDLRFTNIGPDTMRVTWA-PPPSIDLTNFLVRYSPVKNEEDV 1311
E+ + IP P DL N + + VTW+ +D + ++ +K
Sbjct: 1025 YEANEQGNGRTIP--EPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMK---VF 1079
Query: 1312 AELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITA 1371
+ + T+L PG +Y + V ++ + + G P+ + I+
Sbjct: 1080 PPFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAF----IEGFTVPSAVKNIHISP 1135
Query: 1372 N----SFTVHWIAPRATITGYRI---RHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEY 1424
N S TV+W + Y + RH S + +P T L G +Y
Sbjct: 1136 NGATDSLTVNWTPGGGDVDSYTVSAFRH-----SQKVDSQTIPKHVFEHTFHRLEAGEQY 1190
Query: 1425 VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWD-APAVTVRYYRITYG 1483
+ I +++G ++ + + ++ + V + A + SL++SW A V RY +
Sbjct: 1191 QIMIASVSGSLKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDILLLT 1250
Query: 1484 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
E G ++ + P + L PG Y I + V+G SK RT
Sbjct: 1251 ENG--ILLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSG----GLFSKEAQTEGRTVPA 1304
Query: 1544 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
+ +++T+ +S +W S ++ Y + +G + + Q+ LQ
Sbjct: 1305 AVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQSFSFQNLLQ 1364
Query: 1604 PTV-EYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRY 1662
+ + V+ ++ S ES +T ++ +G DS+ W G Y
Sbjct: 1365 GRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRG--SNRNTTDSLWFNWSPASGDFDFY 1422
Query: 1663 RVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAI 1722
+ +P E + D E QGL PG +Y + VV D+ ++ + +S
Sbjct: 1423 ELILYNPNGTKKENWKDKDLTE--WRFQGLVPGRKYVLWVVTHSGDLSNK--VTAESRTA 1478
Query: 1723 PAPTDL-KFTQVTPTSLSAQWT-PPN-VQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1779
P+P L F + TSL+ W PP+ + ++ P++ N S +V
Sbjct: 1479 PSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFNPYN-NRKSEGRIV 1537
Query: 1780 SGLMVATKYEVSVYALKD---TLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRT 1836
GL Y+ +V + S+P G V T + R ++ T I SW
Sbjct: 1538 YGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNS--TAIACSWIP 1595
Query: 1837 KTETITGFQVDAVPANGQ-TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV 1895
G+ ++ + Q R ++ + I L P Y + + + S V
Sbjct: 1596 PDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVV 1655
Query: 1896 VIDASTAIDAP 1906
T ID P
Sbjct: 1656 EDSTITMIDRP 1666
Score = 153 bits (386), Expect = 2e-36
Identities = 264/1265 (20%), Positives = 484/1265 (38%), Gaps = 102/1265 (8%)
Query: 768 LPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSI 827
+ +T N+ DL G Y N IS D E++++L T P A + ++ TS+
Sbjct: 291 IDNTTYGCNLQDLQAGTIY--NFRIISLDEERTVVLQTDPL--PPARFGVSKEKTTSTSL 346
Query: 828 VVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETA--NSVTLSDLQPGVQYNITIYAVEE 885
V W+ +T Y + + + E+ N T +L G +YNI I AV
Sbjct: 347 HVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYNIAITAVSG 406
Query: 886 NQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN 945
+ S V T G+ TVPSP + + I W+ V YR+ ++
Sbjct: 407 GKRSFSVY----TNGS----TVPSPVKDIGISTKANSLLISWSHGSGNVERYRLMLMDKG 458
Query: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQF 1005
+ HG + ++A GL+PG Y V + G ++ +T ++ +NL+
Sbjct: 459 IL-VHGGVVDKHATSYA-FHGLTPGYLYNLTVMTEAAGLQNYRWKLVRTAPMEV-SNLKV 515
Query: 1006 VNETDSTVL-VRWTPPRAQITGYRLTVGLTRRGQPRQYNV-GPSVSKYPLRNLQPASEYT 1063
N+ T L V+W P + Y +T L+ +G ++ V P +++ + L P Y
Sbjct: 516 TNDGSLTSLKVKWQRPPGNVDSYNIT--LSHKGTIKESRVLAPWITETHFKELVPGRLYQ 573
Query: 1064 VSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGV---- 1119
V++ + G + K V T + N ++V++W+P + +
Sbjct: 574 VTVSCVSGELSAQKMA-VGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWEQYRILLFN 632
Query: 1120 ------RPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP 1173
+ G E + V D+G L PG +Y + ++ G +++ P
Sbjct: 633 DSVVLLNITVGKEETQYVMDDTG------LVPGRQYEVEV-IVESGNLKNSERCQGRTVP 685
Query: 1174 LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
L+ AN + L++ W+ TP + + + + + + D T
Sbjct: 686 LAVLQLRVKHANETS--LSIMWQ---TP-VAEWEKYIISLADRDLLLIHKSLSKDAKEFT 739
Query: 1234 FDNLSPGLEYNVSVYTVKDD-KESVPISDTIIPAVPPPTDLRFTNIGPDTMRVT-WAPPP 1291
F +L PG +Y +V ++ D K S + +PA TDL N G + T W
Sbjct: 740 FTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPA--QVTDLHVANQGMTSSLFTNWTQAQ 797
Query: 1292 S-IDLTNFLVRYSPV--KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHEST 1348
++ L+ + V KNE SIS + +L G+ Y V V++V S
Sbjct: 798 GDVEFYQVLLIHENVVIKNE------SISSETSRYSFHSLKSGSLYSVVVTTVSGGISSR 851
Query: 1349 PLRGRQKTGLDSPTGIDFSDITANSF-TVHWIAPRATITGYRIRHHPEHFSGRPREDRVP 1407
+ +T S +G+ ++ N + +V W+ + Y + H + +
Sbjct: 852 QVVVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVTL--SHDGKVVQSLVIA 909
Query: 1408 HSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVV-AATPTSLLI 1466
S + ++LTPG Y V+I +G+ E+ Q+ TV D + + V +A L +
Sbjct: 910 KSVRECSFSSLTPGRLYTVTITTRSGKYENHSF-SQERTVPDKVQGVSVSNSARSDYLRV 968
Query: 1467 SWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD 1526
SW +Y +T N+ +Q ++P S++ L PG Y++TV +G+ +
Sbjct: 969 SWVHATGDFDHYEVTIKNK--NNFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQYE 1026
Query: 1527 SPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVT---TTPKNGPG 1583
+ N RT + + + + + V W ++ V Y + K P
Sbjct: 1027 ANEQG-----NGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFPP 1081
Query: 1584 PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ-----TAVTNID-RPKG 1637
TA TE L P +Y + V + + ++ +AV NI P G
Sbjct: 1082 FHLVNTA----TEYRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNIHISPNG 1137
Query: 1638 LAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSE 1697
DS+ + W G V Y V+ + E T L G +
Sbjct: 1138 AT------DSLTVNWTPGGGDVDSYTVSAFRHSQKVDSQTIPKHVFEHT--FHRLEAGEQ 1189
Query: 1698 YTVSVVALHDDMESQPLIGTQSTAIPAPTD--LKFTQVTPTSLSAQWTPPNVQLTGYRVR 1755
Y + + ++ +++Q I +PA + + SL W Y +
Sbjct: 1190 YQIMIASVSGSLKNQ--INVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDIL 1247
Query: 1756 VTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVS 1815
+ E ++ + + L KY++ + + L S+ AQ T+ +
Sbjct: 1248 LLT-ENGILLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVP--A 1304
Query: 1816 PPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQP 1875
R+T+ + ++ W ++ + + +G + + P V+S++ L
Sbjct: 1305 AVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQSFSFQNLLQ 1364
Query: 1876 GTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFL-ATTPNSLLVSWQPPRARITGYI 1934
G YK+ + T + S+ I T + S+LR T +SL +W P Y
Sbjct: 1365 GRMYKMVIVT-HSGELSNESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPASGDFDFYE 1423
Query: 1935 IKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDEL 1994
+ P +E +TE GL PG +Y ++V+ + ++ +
Sbjct: 1424 LILYNPNGTKKE--NWKDKDLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAESRTAPSP 1481
Query: 1995 PQLVT 1999
P L++
Sbjct: 1482 PSLMS 1486
Score = 150 bits (379), Expect = 1e-35
Identities = 272/1321 (20%), Positives = 506/1321 (38%), Gaps = 92/1321 (6%)
Query: 693 TRFDFTTTSTSTPVTSNTV--TGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGF 750
++++ T+ S S +V G T P SP+ S A+S ++SW S V +
Sbjct: 395 SKYNIAITAVSGGKRSFSVYTNGSTVP-SPVKDIGISTK---ANSLLISWSHGSGNVERY 450
Query: 751 RVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISED-GEQSLILSTSQTT 809
R+ L ++G + ATS L PG Y+ N+ ++E G Q+ +T
Sbjct: 451 RLM--LMDKGILVHGGVVDKHATSYAFHGLTPG--YLYNLTVMTEAAGLQNYRWKLVRTA 506
Query: 810 APDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSD 869
+ + TS+ V+W RP + Y I S + + P + +
Sbjct: 507 PMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWITET-HFKE 565
Query: 870 LQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTP 929
L PG Y +T+ V S + Q+ G D V + + + V+ W+P
Sbjct: 566 LVPGRLYQVTVSCV-----SGELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVS--WSP 618
Query: 930 PESAVTGYRV-----DVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGR 984
P YR+ V+ +N+ + + +T GL PG Y +V S
Sbjct: 619 PAGDWEQYRILLFNDSVVLLNITVGKEETQYVMDDT-----GLVPGRQYEVEVIVESGNL 673
Query: 985 ESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNV 1044
++ +T L A L+ + ++++ + W P A+ Y +++ R ++
Sbjct: 674 KNSERCQGRTVPL-AVLQLRVKHANETSLSIMWQTPVAEWEKYIISLA-DRDLLLIHKSL 731
Query: 1045 GPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIV 1104
++ +L P +Y ++ +I G+ ++ + T + + N +T +++
Sbjct: 732 SKDAKEFTFTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHVANQGMT-SSLF 790
Query: 1105 ITWTPAPR-IGFKLGVRPSQGGEAPRE-VTSDSGSIVVSGLTPGVEYVYTIQVLRDGQER 1162
WT A + F + + E ++S++ L G Y + + G
Sbjct: 791 TNWTQAQGDVEFYQVLLIHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISS 850
Query: 1163 DAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLE 1222
+V P S + + + + L+VSW + D+ Y +T + +G+ SL
Sbjct: 851 RQVVVEGRTVP-SSVSGVTVNNSGRNDYLSVSWLLAPG-DVDNYEVTLSH-DGKVVQSL- 906
Query: 1223 EVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS-DTIIPAVPPPTDLRFTNIGPD 1281
V+ C+F +L+PG Y V++ T E+ S + +P + + D
Sbjct: 907 -VIAKSVRECSFSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVS-NSARSD 964
Query: 1282 TMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAEL-SISPSDNAVVLTNLLPGTEYVVSVSS 1340
+RV+W D ++ V +KN+ + + SI S+N V L+PG Y V+V++
Sbjct: 965 YLRVSWVHATG-DFDHYEVT---IKNKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTT 1020
Query: 1341 VYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGR 1400
Q+E+ +G +T + + + + V W + Y I+
Sbjct: 1021 KSGQYEANE-QGNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVF 1079
Query: 1401 PREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAAT 1460
P V ++ T+LTPG +Y + ++ ++G + I + TV +++ +
Sbjct: 1080 PPFHLV-NTATEYRFTSLTPGRQYKILVLTISGDVQQSAFI-EGFTVPSAVKNIHISPNG 1137
Query: 1461 PT-SLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVY 1519
T SL ++W V Y T + V T+P T L+ G Y I +
Sbjct: 1138 ATDSLTVNWTPGGGDVDSY--TVSAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIMIA 1195
Query: 1520 AVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS-----VKWLPSSSPVTGYRV 1574
+V+G + I++ RT P+ +Q + DN+ S V W ++ Y +
Sbjct: 1196 SVSG-----SLKNQINVVGRTV---PASVQGV-IADNAYSSYSLIVSWQKAAGVAERYDI 1246
Query: 1575 TTTPKNGPGPTKTKTAGPDQTEM-TIEGLQPTVEYVVSVYAQNP---SGESQP---LVQT 1627
+NG T+ P T+ E L P +Y + + + S E+Q V
Sbjct: 1247 LLLTENGI--LLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPA 1304
Query: 1628 AVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTA 1687
AVT+ L T+ + W + +G++S Y + +P+ + E D +
Sbjct: 1305 AVTD------LRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQV-DPLVQSF 1357
Query: 1688 ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNV 1747
Q L G Y + +V ++ ++ I ++ + T SL W+P +
Sbjct: 1358 SFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPASG 1417
Query: 1748 QLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV 1807
Y + + G KE D + GL+ KY + V L+++
Sbjct: 1418 DFDFYELILY--NPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAES 1475
Query: 1808 VTTLENVSPPRRARVTDATETTITISWRTKTE--TITGFQVDAVPANGQTPIQRTIKPDV 1865
T SPP D T++ I+W+ + F++ +P + T
Sbjct: 1476 RTA---PSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKS 1532
Query: 1866 RSYTITGLQPGTDYKIYLYTLNDNA---RSSPVVIDASTAIDAPSNLRFLATTPNSLLVS 1922
+ GL+PG Y+ + T++ ++ S P+ T D NL ++ S
Sbjct: 1533 EGRIVYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACS 1592
Query: 1923 WQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 1982
W PP + GY I+ K + E + + I L P Y + + S
Sbjct: 1593 WIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTS 1652
Query: 1983 E 1983
E
Sbjct: 1653 E 1653
Score = 142 bits (357), Expect = 5e-33
Identities = 249/1241 (20%), Positives = 467/1241 (37%), Gaps = 126/1241 (10%)
Query: 798 EQSLILSTSQ----TTAPDAPPDP-------TVDQVDDTSIVVRWSRPQAPITGYRIVYS 846
+ S +LST+Q TT +P + S+ ++W +P + ++YS
Sbjct: 219 DTSWVLSTTQPFSSTTEETGLAEPERCNFTLAESKASSHSVSIQWRILGSPCN-FSLIYS 277
Query: 847 PSVEGSST--ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
G++ + T L DLQ G YN I +++E E T ++
Sbjct: 278 SDTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFRIISLDE-----------ERTVVLQT 326
Query: 905 DTVPSPR-DLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE 963
D +P R + + T + + WTP VT Y V + N G ++ S ++ E
Sbjct: 327 DPLPPARFGVSKEKTTSTSLHVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQES-TSWNE 385
Query: 964 VT--GLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
T L+ G Y + AVS G+ S + +T + +P ++ +++L+ W+
Sbjct: 386 YTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGST-VPSPVKDIGISTKANSLLISWSHGS 444
Query: 1022 AQITGYRLTV---GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKA 1078
+ YRL + G+ G V + Y L P Y ++++ ++ +
Sbjct: 445 GNVERYRLMLMDKGILVHGGV----VDKHATSYAFHGLTPGYLYNLTVMTEAAGLQNYRW 500
Query: 1079 TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGG--EAPREVTSDSG 1136
V T S++ N + + T++ + W P + S G + R +
Sbjct: 501 KLVRTAPMEVSNLKVTN-DGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWIT 559
Query: 1137 SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGV--LTVS 1194
L PG Y T+ + V + P +LEAN + + L VS
Sbjct: 560 ETHFKELVPGRLYQVTVSCVSGELSAQKMAVGRTF----PDKVANLEANNNGRMRSLVVS 615
Query: 1195 WERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDN--LSPGLEYNVSVYTVKD 1252
W D YRI L V +++ D+ L PG +Y V V
Sbjct: 616 WS-PPAGDWEQYRILLF---NDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESG 671
Query: 1253 D-KESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDV 1311
+ K S +P LR + ++ + W P + + +++ S + +
Sbjct: 672 NLKNSERCQGRTVPLA--VLQLRVKHANETSLSIMWQTPVA-EWEKYII--SLADRDLLL 726
Query: 1312 AELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHESTPLRGRQKTGLDSPTGIDFSDIT 1370
S+S T+L+PG +Y+ +V+S+ + S+ ++GR + + +T
Sbjct: 727 IHKSLSKDAKEFTFTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHVANQGMT 786
Query: 1371 ANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVA 1430
++ FT +W + + Y++ E+ + + + + + +L G+ Y V +
Sbjct: 787 SSLFT-NWTQAQGDVEFYQVLLIHENVV--IKNESISSETSRYSFHSLKSGSLYSVVVTT 843
Query: 1431 LNGREESPLLIGQQSTVSDVPRDLEVVAATPTS----LLISWDAPAVTVRYYRITYGETG 1486
++G S ++ + T VP + V + L +SW V Y +T G
Sbjct: 844 VSGGISSRQVVVEGRT---VPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDG 900
Query: 1487 GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS 1546
VQ + S + S L PG YT+T+ +G+ ++ + S+ RT DK
Sbjct: 901 --KVVQSLVIAKSVRECSFSSLTPGRLYTVTITTRSGKYENHSFSQE-----RTVPDKVQ 953
Query: 1547 QMQVTD-VQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPT 1605
+ V++ + + + V W+ ++ Y VT KN +TK+ + E L P
Sbjct: 954 GVSVSNSARSDYLRVSWVHATGDFDHYEVTIKNKN--NFIQTKSIPKSENECVFVQLVPG 1011
Query: 1606 VEYVVSVYAQNPSGESQPLVQTAVTNIDRP-KGLAFTDVDVDSIKIAWESPQGQVSRYRV 1664
Y V+V + SG+ + Q I P K L + + + + W G V +Y +
Sbjct: 1012 RLYSVTVTTK--SGQYEANEQGNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEI 1069
Query: 1665 TYSSPEDGIHELFPAPDGEEDTA---ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA 1721
+ ++FP P +TA L PG +Y + V+ + D++ I
Sbjct: 1070 QLLFND---MKVFP-PFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFI----EG 1121
Query: 1722 IPAPTDLKFTQVTPT----SLSAQWTPPNVQLTGYRV-----------RVTPKEKTGPMK 1766
P+ +K ++P SL+ WTP + Y V + PK
Sbjct: 1122 FTVPSAVKNIHISPNGATDSLTVNWTPGGGDVDSYTVSAFRHSQKVDSQTIPKHVFEHTF 1181
Query: 1767 EINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDAT 1826
A + ++++ + + K +++V QGV+ +
Sbjct: 1182 HRLEAGEQYQIMIASVSGSLKNQINVVG---RTVPASVQGVIAD------------NAYS 1226
Query: 1827 ETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKP-DVRSYTITGLQPGTDYKIYLYT 1885
++ +SW+ + + + NG ++ T +P + + L PG YKI + T
Sbjct: 1227 SYSLIVSWQKAAGVAERYDILLLTENG-ILLRNTSEPATTKQHKFEDLTPGKKYKIQILT 1285
Query: 1886 LNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPR 1945
++ S + T A ++LR + L W ++ Y I P +
Sbjct: 1286 VSGGLFSKEAQTEGRTVPAAVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQ 1345
Query: 1946 EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLI 1986
E + P V + L G Y + ++ +E I
Sbjct: 1346 ERA-QVDPLVQSFSFQNLLQGRMYKMVIVTHSGELSNESFI 1385
Score = 102 bits (255), Expect = 3e-21
Identities = 218/1016 (21%), Positives = 374/1016 (36%), Gaps = 81/1016 (7%)
Query: 698 TTTSTSTPV-TSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYEL 756
T TS S + S++V G T P V + SS +W A V ++V L
Sbjct: 752 TVTSISGDLKNSSSVKGRTVPAQ--VTDLHVANQGMTSSLFTNWTQAQGDVEFYQVL--L 807
Query: 757 SEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPD 816
E + + S + + L G Y V V +S G S + T P +
Sbjct: 808 IHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVS-GGISSRQVVVEGRTVPSSVSG 866
Query: 817 PTVDQVDDTSIV-VRWSRPQAPITGYRIVYSPSVEGSSTE-LNLPETANSVTLSDLQPGV 874
TV+ + V W + Y + S +G + L + ++ + S L PG
Sbjct: 867 VTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSH--DGKVVQSLVIAKSVRECSFSSLTPGR 924
Query: 875 QYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK----VTIMWTPP 930
Y +TI E+ QE T P +Q V V++ + + W
Sbjct: 925 LYTVTITTRSGKYENHS--FSQERT---------VPDKVQGVSVSNSARSDYLRVSWVHA 973
Query: 931 ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLT 990
Y V + N + +P S N V L PG Y V S E+
Sbjct: 974 TGDFDHYEVTIKNKN-NFIQTKSIPKSENECVFVQ-LVPGRLYSVTVTTKSGQYEANEQG 1031
Query: 991 AQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSK 1050
+T + +L N + + V W+ + Y + + +++ + ++
Sbjct: 1032 NGRTIP-EPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFPPFHLVNTATE 1090
Query: 1051 YPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
Y +L P +Y + ++ I G+ + FT +I T++ + + WTP
Sbjct: 1091 YRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATDS-LTVNWTPG 1149
Query: 1111 PRIGFKLGV---RPSQGGEA---PREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164
V R SQ ++ P+ V + L G +Y I + +
Sbjct: 1150 GGDVDSYTVSAFRHSQKVDSQTIPKHVFEHT----FHRLEAGEQYQIMIASVSGSLKNQI 1205
Query: 1165 PIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEV 1224
+V + V P S + A ++ VSW+++ Y I NG + E
Sbjct: 1206 NVVGRTV-PASVQGVIADNAYSSYSLI-VSWQKAAGV-AERYDILLLTENGILLRNTSEP 1262
Query: 1225 VHADQSSCTFDNLSPGLEYNVSVYTVKD---DKESVPISDTIIPAVPPPTDLRFTNIGPD 1281
Q F++L+PG +Y + + TV KE+ T+ AV TDLR T
Sbjct: 1263 ATTKQHK--FEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAV---TDLRITENSTR 1317
Query: 1282 TMRVTW-APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY-VVSVS 1339
+ W A + N + Y+P N ++ A+ + P + NLL G Y +V V+
Sbjct: 1318 HLSFRWTASEGELSWYNIFL-YNPDGNLQERAQ--VDPLVQSFSFQNLLQGRMYKMVIVT 1374
Query: 1340 SVYEQHESTPLRGRQ-KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYR-IRHHPEHF 1397
E + + GR + G + + T +S +W Y I ++P
Sbjct: 1375 HSGELSNESFIFGRTVPASVSHLRGSNRN--TTDSLWFNWSPASGDFDFYELILYNP--- 1429
Query: 1398 SGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVV 1457
+G +E+ L PG +YV+ +V +G + S + + T P +
Sbjct: 1430 NGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSG-DLSNKVTAESRTAPSPPSLMSFA 1488
Query: 1458 AATPTSLLISWDAPAVTVRY--YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYT 1515
TSL I+W P Y + + + + + S+ + GL+PG Y
Sbjct: 1489 DIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRI-VYGLRPGRSYQ 1547
Query: 1516 ITVYAVTGRGDS-PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRV 1574
V V+G DS SKPI + RT+ DK + +I+ W+P S GY +
Sbjct: 1548 FNVKTVSG--DSWKTYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSI 1605
Query: 1575 TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR 1634
+ ++ +++ + I L P Y+VS+ Q+ S+ + + +T IDR
Sbjct: 1606 ECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDR 1665
Query: 1635 P-----------KGLAFTDVDVD-SIKIAWESPQGQVSRYRVTYSSPEDGIHELFP 1678
P K + + ++ ++ +W S +Y DG EL P
Sbjct: 1666 PPPPPPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKYFTVVVREADGSDELKP 1721
Score = 35.4 bits (80), Expect = 0.67
Identities = 37/194 (19%), Positives = 76/194 (39%), Gaps = 25/194 (12%)
Query: 628 IQWNAPQP-SHISKYILRWRPKNSV---GRWKEATIPGHLNSYTIKGLKPGVVYEGQLIS 683
I W P + + + L+W P++++ + G + + GL+PG Y+ + +
Sbjct: 1497 ITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRI----VYGLRPGRSYQFNVKT 1552
Query: 684 IQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSA 743
+ + ++ F + T N L ++ T I S W+
Sbjct: 1553 VSGDSWKTYSKPIFGSVRTKPDKIQN-----------LHCRPQNSTAIACS-----WIPP 1596
Query: 744 SDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLIL 803
G+ +E + + L + +NI L+P ++Y+V++ ++ G S ++
Sbjct: 1597 DSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSI-KVQSAGMTSEVV 1655
Query: 804 STSQTTAPDAPPDP 817
S T D PP P
Sbjct: 1656 EDSTITMIDRPPPP 1669
>gi|157952213 protein tyrosine phosphatase, receptor type, B isoform b
precursor [Homo sapiens]
Length = 1997
Score = 164 bits (416), Expect = 7e-40
Identities = 281/1370 (20%), Positives = 531/1370 (38%), Gaps = 122/1370 (8%)
Query: 668 IKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSES 727
++ L+ G +Y ++IS+ + TV +T P P S
Sbjct: 82 LQDLQAGTIYNFRIISLDE---------------------ERTVVLQTDPLPP-ARFGVS 119
Query: 728 VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT--SVNIPDLLPGRK 785
+ T++S V W +S V+ + V+ E + Q + + + + +L G K
Sbjct: 120 KEKTTSTSLHVWWTPSSGKVTSYEVQL-FDENNQKIQGVQIQESTSWNEYTFFNLTAGSK 178
Query: 786 YIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVY 845
Y + + +S G++S + T+ +T P D + S+++ WS + YR++
Sbjct: 179 YNIAITAVS-GGKRSFSVYTNGSTVPSPVKDIGIS-TKANSLLISWSHGSGNVERYRLML 236
Query: 846 SPS---VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTP 902
V G + + A S L PG YN+T+ ++ + +
Sbjct: 237 MDKGILVHGGVVDKH----ATSYAFHGLTPGYLYNLTVMTEAAGLQNYRWKLVRT----- 287
Query: 903 RSDTVPSPRDLQFVEVTD----VKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP-IS 957
+P ++ ++VT+ + + W P V Y + + E P I+
Sbjct: 288 ------APMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWIT 341
Query: 958 RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDS-TVLVR 1016
F E L PG Y V VS G S A T D NL+ N +++V
Sbjct: 342 ETHFKE---LVPGRLYQVTVSCVS-GELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVS 397
Query: 1017 WTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN--LQPASEYTVSLVAIKGNQE 1074
W+PP YR+ + VG ++Y + + L P +Y V ++ GN +
Sbjct: 398 WSPPAGDWEQYRILL-FNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLK 456
Query: 1075 SPKATGVFTTLQPGSSIPPYNTEVTETTIVITW-TP-APRIGFKLGVRPSQGGEAPREVT 1132
+ + T P + + ET++ I W TP A + + + + ++
Sbjct: 457 NSERCQGRTV--PLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIHKSLS 514
Query: 1133 SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLT 1192
D+ + L PG +Y+ T+ + + + + + V + T+LH+ T L
Sbjct: 515 KDAKEFTFTDLVPGRKYMATVTSISGDLKNSSSVKGRTVP--AQVTDLHVANQGMTSSLF 572
Query: 1193 VSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD 1252
+W ++ D+ Y++ N N E + ++ S +F +L G Y+V V TV
Sbjct: 573 TNWTQAQG-DVEFYQVLLIHENVVIKN---ESISSETSRYSFHSLKSGSLYSVVVTTVSG 628
Query: 1253 DKES--VPISDTIIPAVPPPTDLRFTNIGP-DTMRVTWAPPPSIDLTNFLVRYSPVKNEE 1309
S V + +P+ + + N G D + V+W P D+ N+ V S + +
Sbjct: 629 GISSRQVVVEGRTVPS--SVSGVTVNNSGRNDYLSVSWLLAPG-DVDNYEVTLS--HDGK 683
Query: 1310 DVAELSISPSDNAVVLTNLLPGTEYVVSV---SSVYEQHESTPLRGRQKTGLDSPTGIDF 1366
V L I+ S ++L PG Y V++ S YE H + +++T D G+
Sbjct: 684 VVQSLVIAKSVRECSFSSLTPGRLYTVTITTRSGKYENHSFS----QERTVPDKVQGVSV 739
Query: 1367 SDITANSFT-VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYV 1425
S+ + + V W+ Y + ++ + + +P S N L PG Y
Sbjct: 740 SNSARSDYLRVSWVHATGDFDHYEVTIKNKNNFIQTKS--IPKSENECVFVQLVPGRLYS 797
Query: 1426 VSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRIT--YG 1483
V++ +G+ E+ G T+ + +DL + + L ++W V Y I +
Sbjct: 798 VTVTTKSGQYEANEQ-GNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFN 856
Query: 1484 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
+ P F + + + + L PG Y I V ++G A + ++ +
Sbjct: 857 DMKVFPP---FHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNI 913
Query: 1544 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
S TD S++V W P V Y V+ + ++T E T L+
Sbjct: 914 HISPNGATD----SLTVNWTPGGGDVDSYTVSAFRHSQK--VDSQTIPKHVFEHTFHRLE 967
Query: 1604 PTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYR 1663
+Y + + + + S ++Q V +A S+ ++W+ G RY
Sbjct: 968 AGEQYQIMIASVSGSLKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYD 1027
Query: 1664 VTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP 1723
+ + E+GI + + + L PG +Y + ++ + + S+ T
Sbjct: 1028 ILLLT-ENGILLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPA 1086
Query: 1724 APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE-INLAPDSSSVVVSGL 1782
A TDL+ T+ + LS +WT +L+ Y + + + G ++E + P S L
Sbjct: 1087 AVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPD--GNLQERAQVDPLVQSFSFQNL 1144
Query: 1783 MVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETIT 1842
+ Y++ + L++ T +VS R + T ++ +W +
Sbjct: 1145 LQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRN--TTDSLWFNWSPASGDFD 1202
Query: 1843 GFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA 1902
+++ NG T + D+ + GL PG Y +++ T + S+ V ++ TA
Sbjct: 1203 FYELILYNPNG-TKKENWKDKDLTEWRFQGLVPGRKYVLWVVT-HSGDLSNKVTAESRTA 1260
Query: 1903 IDAPSNLRFLATTPNSLLVSWQ--PPRARITGYIIKYEKPGSPPREVVPRPRPGVTEAT- 1959
PS + F SL ++W+ P + +++ PR+ + P +
Sbjct: 1261 PSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQW-----LPRDALTVFNPYNNRKSE 1315
Query: 1960 ---ITGLEPGTEYTIYVIALKNNQ---KSEPLIG--RKKTDELPQLVTLP 2001
+ GL PG Y V + + S+P+ G R K D++ L P
Sbjct: 1316 GRIVYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRP 1365
Score = 154 bits (389), Expect = 1e-36
Identities = 268/1271 (21%), Positives = 471/1271 (37%), Gaps = 99/1271 (7%)
Query: 662 HLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPL 721
H SY GL PG +Y L + + + R+ T +P+
Sbjct: 251 HATSYAFHGLTPGYLY--NLTVMTEAAGLQNYRWKLVRT------------------APM 290
Query: 722 VATSESVT-EITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
++ VT + + +S V W V + + LS +G + L T + +L
Sbjct: 291 EVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNI--TLSHKGTIKESRVLAPWITETHFKEL 348
Query: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDD-TSIVVRWSRPQAPIT 839
+PGR Y V V +S GE S T PD + + S+VV WS P
Sbjct: 349 VPGRLYQVTVSCVS--GELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWE 406
Query: 840 GYRI-VYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898
YRI +++ SV + + ET + + L PG QY + + N +++
Sbjct: 407 QYRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLKNSE------- 459
Query: 899 TGTPRSDTVP-SPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS 957
+ TVP + L+ + ++IMW P + Y + + +L H + L
Sbjct: 460 --RCQGRTVPLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIH-KSLSKD 516
Query: 958 RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE-TDSTVLVR 1016
F T L PG Y V ++S ++ +T T+L N+ S++
Sbjct: 517 AKEFT-FTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPAQV-TDLHVANQGMTSSLFTN 574
Query: 1017 WTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
WT + + Y++ + + + ++ S+Y +L+ S Y+V + + G S
Sbjct: 575 WTQAQGDVEFYQVLL-IHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSR 633
Query: 1077 KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPRE--VTSD 1134
+ T+ S N + ++W AP V S G+ + +
Sbjct: 634 QVVVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAKS 693
Query: 1135 SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVS 1194
S LTPG Y TI E + + V ++ A D L VS
Sbjct: 694 VRECSFSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSD--YLRVS 751
Query: 1195 WERSTTPDITGYRITTTPTNGQQGNSLE-EVVHADQSSCTFDNLSPGLEYNVSVYTVKDD 1253
W + T D Y +T N N ++ + + ++ C F L PG Y+V+V T
Sbjct: 752 WVHA-TGDFDHYEVTIKNKN----NFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQ 806
Query: 1254 KESVPISD-TIIPAVPPPTDLRFTNIGPDTMRVTWA-PPPSIDLTNFLVRYSPVKNEEDV 1311
E+ + IP P DL N + + VTW+ +D + ++ +K
Sbjct: 807 YEANEQGNGRTIP--EPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMK---VF 861
Query: 1312 AELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITA 1371
+ + T+L PG +Y + V ++ + + G P+ + I+
Sbjct: 862 PPFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAF----IEGFTVPSAVKNIHISP 917
Query: 1372 N----SFTVHWIAPRATITGYRI---RHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEY 1424
N S TV+W + Y + RH S + +P T L G +Y
Sbjct: 918 NGATDSLTVNWTPGGGDVDSYTVSAFRH-----SQKVDSQTIPKHVFEHTFHRLEAGEQY 972
Query: 1425 VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWD-APAVTVRYYRITYG 1483
+ I +++G ++ + + ++ + V + A + SL++SW A V RY +
Sbjct: 973 QIMIASVSGSLKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDILLLT 1032
Query: 1484 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
E G ++ + P + L PG Y I + V+G SK RT
Sbjct: 1033 ENG--ILLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSG----GLFSKEAQTEGRTVPA 1086
Query: 1544 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
+ +++T+ +S +W S ++ Y + +G + + Q+ LQ
Sbjct: 1087 AVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQSFSFQNLLQ 1146
Query: 1604 PTV-EYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRY 1662
+ + V+ ++ S ES +T ++ +G DS+ W G Y
Sbjct: 1147 GRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRG--SNRNTTDSLWFNWSPASGDFDFY 1204
Query: 1663 RVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAI 1722
+ +P E + D E QGL PG +Y + VV D+ ++ + +S
Sbjct: 1205 ELILYNPNGTKKENWKDKDLTE--WRFQGLVPGRKYVLWVVTHSGDLSNK--VTAESRTA 1260
Query: 1723 PAPTDL-KFTQVTPTSLSAQWT-PPN-VQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1779
P+P L F + TSL+ W PP+ + ++ P++ N S +V
Sbjct: 1261 PSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFNPYN-NRKSEGRIV 1319
Query: 1780 SGLMVATKYEVSVYALKD---TLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRT 1836
GL Y+ +V + S+P G V T + R ++ T I SW
Sbjct: 1320 YGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNS--TAIACSWIP 1377
Query: 1837 KTETITGFQVDAVPANGQ-TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV 1895
G+ ++ + Q R ++ + I L P Y + + + S V
Sbjct: 1378 PDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVV 1437
Query: 1896 VIDASTAIDAP 1906
T ID P
Sbjct: 1438 EDSTITMIDRP 1448
Score = 153 bits (386), Expect = 2e-36
Identities = 264/1265 (20%), Positives = 484/1265 (38%), Gaps = 102/1265 (8%)
Query: 768 LPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSI 827
+ +T N+ DL G Y N IS D E++++L T P A + ++ TS+
Sbjct: 73 IDNTTYGCNLQDLQAGTIY--NFRIISLDEERTVVLQTDPL--PPARFGVSKEKTTSTSL 128
Query: 828 VVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETA--NSVTLSDLQPGVQYNITIYAVEE 885
V W+ +T Y + + + E+ N T +L G +YNI I AV
Sbjct: 129 HVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYNIAITAVSG 188
Query: 886 NQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN 945
+ S V T G+ TVPSP + + I W+ V YR+ ++
Sbjct: 189 GKRSFSVY----TNGS----TVPSPVKDIGISTKANSLLISWSHGSGNVERYRLMLMDKG 240
Query: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQF 1005
+ HG + ++A GL+PG Y V + G ++ +T ++ +NL+
Sbjct: 241 IL-VHGGVVDKHATSYA-FHGLTPGYLYNLTVMTEAAGLQNYRWKLVRTAPMEV-SNLKV 297
Query: 1006 VNETDSTVL-VRWTPPRAQITGYRLTVGLTRRGQPRQYNV-GPSVSKYPLRNLQPASEYT 1063
N+ T L V+W P + Y +T L+ +G ++ V P +++ + L P Y
Sbjct: 298 TNDGSLTSLKVKWQRPPGNVDSYNIT--LSHKGTIKESRVLAPWITETHFKELVPGRLYQ 355
Query: 1064 VSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGV---- 1119
V++ + G + K V T + N ++V++W+P + +
Sbjct: 356 VTVSCVSGELSAQKMA-VGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWEQYRILLFN 414
Query: 1120 ------RPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP 1173
+ G E + V D+G L PG +Y + ++ G +++ P
Sbjct: 415 DSVVLLNITVGKEETQYVMDDTG------LVPGRQYEVEV-IVESGNLKNSERCQGRTVP 467
Query: 1174 LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
L+ AN + L++ W+ TP + + + + + + D T
Sbjct: 468 LAVLQLRVKHANETS--LSIMWQ---TP-VAEWEKYIISLADRDLLLIHKSLSKDAKEFT 521
Query: 1234 FDNLSPGLEYNVSVYTVKDD-KESVPISDTIIPAVPPPTDLRFTNIGPDTMRVT-WAPPP 1291
F +L PG +Y +V ++ D K S + +PA TDL N G + T W
Sbjct: 522 FTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPA--QVTDLHVANQGMTSSLFTNWTQAQ 579
Query: 1292 S-IDLTNFLVRYSPV--KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHEST 1348
++ L+ + V KNE SIS + +L G+ Y V V++V S
Sbjct: 580 GDVEFYQVLLIHENVVIKNE------SISSETSRYSFHSLKSGSLYSVVVTTVSGGISSR 633
Query: 1349 PLRGRQKTGLDSPTGIDFSDITANSF-TVHWIAPRATITGYRIRHHPEHFSGRPREDRVP 1407
+ +T S +G+ ++ N + +V W+ + Y + H + +
Sbjct: 634 QVVVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVTL--SHDGKVVQSLVIA 691
Query: 1408 HSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVV-AATPTSLLI 1466
S + ++LTPG Y V+I +G+ E+ Q+ TV D + + V +A L +
Sbjct: 692 KSVRECSFSSLTPGRLYTVTITTRSGKYENHSF-SQERTVPDKVQGVSVSNSARSDYLRV 750
Query: 1467 SWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD 1526
SW +Y +T N+ +Q ++P S++ L PG Y++TV +G+ +
Sbjct: 751 SWVHATGDFDHYEVTIKNK--NNFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQYE 808
Query: 1527 SPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVT---TTPKNGPG 1583
+ N RT + + + + + V W ++ V Y + K P
Sbjct: 809 ANEQG-----NGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFPP 863
Query: 1584 PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ-----TAVTNID-RPKG 1637
TA TE L P +Y + V + + ++ +AV NI P G
Sbjct: 864 FHLVNTA----TEYRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNIHISPNG 919
Query: 1638 LAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSE 1697
DS+ + W G V Y V+ + E T L G +
Sbjct: 920 AT------DSLTVNWTPGGGDVDSYTVSAFRHSQKVDSQTIPKHVFEHT--FHRLEAGEQ 971
Query: 1698 YTVSVVALHDDMESQPLIGTQSTAIPAPTD--LKFTQVTPTSLSAQWTPPNVQLTGYRVR 1755
Y + + ++ +++Q I +PA + + SL W Y +
Sbjct: 972 YQIMIASVSGSLKNQ--INVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDIL 1029
Query: 1756 VTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVS 1815
+ E ++ + + L KY++ + + L S+ AQ T+ +
Sbjct: 1030 LLT-ENGILLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVP--A 1086
Query: 1816 PPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQP 1875
R+T+ + ++ W ++ + + +G + + P V+S++ L
Sbjct: 1087 AVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQSFSFQNLLQ 1146
Query: 1876 GTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFL-ATTPNSLLVSWQPPRARITGYI 1934
G YK+ + T + S+ I T + S+LR T +SL +W P Y
Sbjct: 1147 GRMYKMVIVT-HSGELSNESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPASGDFDFYE 1205
Query: 1935 IKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDEL 1994
+ P +E +TE GL PG +Y ++V+ + ++ +
Sbjct: 1206 LILYNPNGTKKE--NWKDKDLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAESRTAPSP 1263
Query: 1995 PQLVT 1999
P L++
Sbjct: 1264 PSLMS 1268
Score = 150 bits (379), Expect = 1e-35
Identities = 272/1321 (20%), Positives = 506/1321 (38%), Gaps = 92/1321 (6%)
Query: 693 TRFDFTTTSTSTPVTSNTV--TGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGF 750
++++ T+ S S +V G T P SP+ S A+S ++SW S V +
Sbjct: 177 SKYNIAITAVSGGKRSFSVYTNGSTVP-SPVKDIGISTK---ANSLLISWSHGSGNVERY 232
Query: 751 RVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISED-GEQSLILSTSQTT 809
R+ L ++G + ATS L PG Y+ N+ ++E G Q+ +T
Sbjct: 233 RLM--LMDKGILVHGGVVDKHATSYAFHGLTPG--YLYNLTVMTEAAGLQNYRWKLVRTA 288
Query: 810 APDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSD 869
+ + TS+ V+W RP + Y I S + + P + +
Sbjct: 289 PMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWITET-HFKE 347
Query: 870 LQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTP 929
L PG Y +T+ V S + Q+ G D V + + + V+ W+P
Sbjct: 348 LVPGRLYQVTVSCV-----SGELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVS--WSP 400
Query: 930 PESAVTGYRV-----DVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGR 984
P YR+ V+ +N+ + + +T GL PG Y +V S
Sbjct: 401 PAGDWEQYRILLFNDSVVLLNITVGKEETQYVMDDT-----GLVPGRQYEVEVIVESGNL 455
Query: 985 ESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNV 1044
++ +T L A L+ + ++++ + W P A+ Y +++ R ++
Sbjct: 456 KNSERCQGRTVPL-AVLQLRVKHANETSLSIMWQTPVAEWEKYIISLA-DRDLLLIHKSL 513
Query: 1045 GPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIV 1104
++ +L P +Y ++ +I G+ ++ + T + + N +T +++
Sbjct: 514 SKDAKEFTFTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHVANQGMT-SSLF 572
Query: 1105 ITWTPAPR-IGFKLGVRPSQGGEAPRE-VTSDSGSIVVSGLTPGVEYVYTIQVLRDGQER 1162
WT A + F + + E ++S++ L G Y + + G
Sbjct: 573 TNWTQAQGDVEFYQVLLIHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISS 632
Query: 1163 DAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLE 1222
+V P S + + + + L+VSW + D+ Y +T + +G+ SL
Sbjct: 633 RQVVVEGRTVP-SSVSGVTVNNSGRNDYLSVSWLLAPG-DVDNYEVTLSH-DGKVVQSL- 688
Query: 1223 EVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS-DTIIPAVPPPTDLRFTNIGPD 1281
V+ C+F +L+PG Y V++ T E+ S + +P + + D
Sbjct: 689 -VIAKSVRECSFSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVS-NSARSD 746
Query: 1282 TMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAEL-SISPSDNAVVLTNLLPGTEYVVSVSS 1340
+RV+W D ++ V +KN+ + + SI S+N V L+PG Y V+V++
Sbjct: 747 YLRVSWVHATG-DFDHYEVT---IKNKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTT 802
Query: 1341 VYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGR 1400
Q+E+ +G +T + + + + V W + Y I+
Sbjct: 803 KSGQYEANE-QGNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVF 861
Query: 1401 PREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAAT 1460
P V ++ T+LTPG +Y + ++ ++G + I + TV +++ +
Sbjct: 862 PPFHLV-NTATEYRFTSLTPGRQYKILVLTISGDVQQSAFI-EGFTVPSAVKNIHISPNG 919
Query: 1461 PT-SLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVY 1519
T SL ++W V Y T + V T+P T L+ G Y I +
Sbjct: 920 ATDSLTVNWTPGGGDVDSY--TVSAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIMIA 977
Query: 1520 AVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS-----VKWLPSSSPVTGYRV 1574
+V+G + I++ RT P+ +Q + DN+ S V W ++ Y +
Sbjct: 978 SVSG-----SLKNQINVVGRTV---PASVQGV-IADNAYSSYSLIVSWQKAAGVAERYDI 1028
Query: 1575 TTTPKNGPGPTKTKTAGPDQTEM-TIEGLQPTVEYVVSVYAQNP---SGESQP---LVQT 1627
+NG T+ P T+ E L P +Y + + + S E+Q V
Sbjct: 1029 LLLTENGI--LLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPA 1086
Query: 1628 AVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTA 1687
AVT+ L T+ + W + +G++S Y + +P+ + E D +
Sbjct: 1087 AVTD------LRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQV-DPLVQSF 1139
Query: 1688 ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNV 1747
Q L G Y + +V ++ ++ I ++ + T SL W+P +
Sbjct: 1140 SFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPASG 1199
Query: 1748 QLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV 1807
Y + + G KE D + GL+ KY + V L+++
Sbjct: 1200 DFDFYELILY--NPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAES 1257
Query: 1808 VTTLENVSPPRRARVTDATETTITISWRTKTE--TITGFQVDAVPANGQTPIQRTIKPDV 1865
T SPP D T++ I+W+ + F++ +P + T
Sbjct: 1258 RTA---PSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKS 1314
Query: 1866 RSYTITGLQPGTDYKIYLYTLNDNA---RSSPVVIDASTAIDAPSNLRFLATTPNSLLVS 1922
+ GL+PG Y+ + T++ ++ S P+ T D NL ++ S
Sbjct: 1315 EGRIVYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACS 1374
Query: 1923 WQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 1982
W PP + GY I+ K + E + + I L P Y + + S
Sbjct: 1375 WIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTS 1434
Query: 1983 E 1983
E
Sbjct: 1435 E 1435
Score = 141 bits (356), Expect = 7e-33
Identities = 241/1202 (20%), Positives = 454/1202 (37%), Gaps = 115/1202 (9%)
Query: 826 SIVVRWSRPQAPITGYRIVYSPSVEGSST--ELNLPETANSVTLSDLQPGVQYNITIYAV 883
S+ ++W +P + ++YS G++ + T L DLQ G YN I ++
Sbjct: 40 SVSIQWRILGSPCN-FSLIYSSDTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFRIISL 98
Query: 884 EENQESTPVVIQQETTGTPRSDTVPSPR-DLQFVEVTDVKVTIMWTPPESAVTGYRVDVI 942
+E E T ++D +P R + + T + + WTP VT Y V +
Sbjct: 99 DE-----------ERTVVLQTDPLPPARFGVSKEKTTSTSLHVWWTPSSGKVTSYEVQLF 147
Query: 943 PVNLPGEHGQRLPISRNTFAEVT--GLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAP 1000
N G ++ S ++ E T L+ G Y + AVS G+ S + +T + +P
Sbjct: 148 DENNQKIQGVQIQES-TSWNEYTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGST-VPSP 205
Query: 1001 TNLQFVNETDSTVLVRWTPPRAQITGYRLTV---GLTRRGQPRQYNVGPSVSKYPLRNLQ 1057
++ +++L+ W+ + YRL + G+ G V + Y L
Sbjct: 206 VKDIGISTKANSLLISWSHGSGNVERYRLMLMDKGILVHGGV----VDKHATSYAFHGLT 261
Query: 1058 PASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKL 1117
P Y ++++ ++ + V T S++ N + + T++ + W P
Sbjct: 262 PGYLYNLTVMTEAAGLQNYRWKLVRTAPMEVSNLKVTN-DGSLTSLKVKWQRPPGNVDSY 320
Query: 1118 GVRPSQGG--EAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLS 1175
+ S G + R + L PG Y T+ + V +
Sbjct: 321 NITLSHKGTIKESRVLAPWITETHFKELVPGRLYQVTVSCVSGELSAQKMAVGRTF---- 376
Query: 1176 PPTNLHLEANPDTGV--LTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
P +LEAN + + L VSW D YRI L V +++
Sbjct: 377 PDKVANLEANNNGRMRSLVVSWS-PPAGDWEQYRILLF---NDSVVLLNITVGKEETQYV 432
Query: 1234 FDN--LSPGLEYNVSVYTVKDD-KESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP 1290
D+ L PG +Y V V + K S +P LR + ++ + W P
Sbjct: 433 MDDTGLVPGRQYEVEVIVESGNLKNSERCQGRTVPLA--VLQLRVKHANETSLSIMWQTP 490
Query: 1291 PSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHESTP 1349
+ + +++ S + + S+S T+L+PG +Y+ +V+S+ + S+
Sbjct: 491 VA-EWEKYII--SLADRDLLLIHKSLSKDAKEFTFTDLVPGRKYMATVTSISGDLKNSSS 547
Query: 1350 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS 1409
++GR + + +T++ FT +W + + Y++ E+ + + +
Sbjct: 548 VKGRTVPAQVTDLHVANQGMTSSLFT-NWTQAQGDVEFYQVLLIHENVV--IKNESISSE 604
Query: 1410 RNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTS----LL 1465
+ + +L G+ Y V + ++G S ++ + T VP + V + L
Sbjct: 605 TSRYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRT---VPSSVSGVTVNNSGRNDYLS 661
Query: 1466 ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1525
+SW V Y +T G VQ + S + S L PG YT+T+ +G+
Sbjct: 662 VSWLLAPGDVDNYEVTLSHDG--KVVQSLVIAKSVRECSFSSLTPGRLYTVTITTRSGKY 719
Query: 1526 DSPASSKPISINYRTEIDKPSQMQVTD-VQDNSISVKWLPSSSPVTGYRVTTTPKNGPGP 1584
++ + S+ RT DK + V++ + + + V W+ ++ Y VT KN
Sbjct: 720 ENHSFSQE-----RTVPDKVQGVSVSNSARSDYLRVSWVHATGDFDHYEVTIKNKN--NF 772
Query: 1585 TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRP-KGLAFTDV 1643
+TK+ + E L P Y V+V + SG+ + Q I P K L +
Sbjct: 773 IQTKSIPKSENECVFVQLVPGRLYSVTVTTK--SGQYEANEQGNGRTIPEPVKDLTLRNR 830
Query: 1644 DVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTA---ELQGLRPGSEYTV 1700
+ + + W G V +Y + + ++FP P +TA L PG +Y +
Sbjct: 831 STEDLHVTWSGANGDVDQYEIQLLFND---MKVFP-PFHLVNTATEYRFTSLTPGRQYKI 886
Query: 1701 SVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPT----SLSAQWTPPNVQLTGYRV-- 1754
V+ + D++ I P+ +K ++P SL+ WTP + Y V
Sbjct: 887 LVLTISGDVQQSAFI----EGFTVPSAVKNIHISPNGATDSLTVNWTPGGGDVDSYTVSA 942
Query: 1755 ---------RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ 1805
+ PK A + ++++ + + K +++V Q
Sbjct: 943 FRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGSLKNQINVVG---RTVPASVQ 999
Query: 1806 GVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKP-D 1864
GV+ + ++ +SW+ + + + NG ++ T +P
Sbjct: 1000 GVIAD------------NAYSSYSLIVSWQKAAGVAERYDILLLTENG-ILLRNTSEPAT 1046
Query: 1865 VRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQ 1924
+ + L PG YKI + T++ S + T A ++LR + L W
Sbjct: 1047 TKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITENSTRHLSFRWT 1106
Query: 1925 PPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
++ Y I P +E + P V + L G Y + ++ +E
Sbjct: 1107 ASEGELSWYNIFLYNPDGNLQERA-QVDPLVQSFSFQNLLQGRMYKMVIVTHSGELSNES 1165
Query: 1985 LI 1986
I
Sbjct: 1166 FI 1167
Score = 102 bits (255), Expect = 3e-21
Identities = 218/1016 (21%), Positives = 374/1016 (36%), Gaps = 81/1016 (7%)
Query: 698 TTTSTSTPV-TSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYEL 756
T TS S + S++V G T P V + SS +W A V ++V L
Sbjct: 534 TVTSISGDLKNSSSVKGRTVPAQ--VTDLHVANQGMTSSLFTNWTQAQGDVEFYQVL--L 589
Query: 757 SEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPD 816
E + + S + + L G Y V V +S G S + T P +
Sbjct: 590 IHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVS-GGISSRQVVVEGRTVPSSVSG 648
Query: 817 PTVDQVDDTSIV-VRWSRPQAPITGYRIVYSPSVEGSSTE-LNLPETANSVTLSDLQPGV 874
TV+ + V W + Y + S +G + L + ++ + S L PG
Sbjct: 649 VTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSH--DGKVVQSLVIAKSVRECSFSSLTPGR 706
Query: 875 QYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK----VTIMWTPP 930
Y +TI E+ QE T P +Q V V++ + + W
Sbjct: 707 LYTVTITTRSGKYENHS--FSQERT---------VPDKVQGVSVSNSARSDYLRVSWVHA 755
Query: 931 ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLT 990
Y V + N + +P S N V L PG Y V S E+
Sbjct: 756 TGDFDHYEVTIKNKN-NFIQTKSIPKSENECVFVQ-LVPGRLYSVTVTTKSGQYEANEQG 813
Query: 991 AQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSK 1050
+T + +L N + + V W+ + Y + + +++ + ++
Sbjct: 814 NGRTIP-EPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFPPFHLVNTATE 872
Query: 1051 YPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
Y +L P +Y + ++ I G+ + FT +I T++ + + WTP
Sbjct: 873 YRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATDS-LTVNWTPG 931
Query: 1111 PRIGFKLGV---RPSQGGEA---PREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164
V R SQ ++ P+ V + L G +Y I + +
Sbjct: 932 GGDVDSYTVSAFRHSQKVDSQTIPKHVFEHT----FHRLEAGEQYQIMIASVSGSLKNQI 987
Query: 1165 PIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEV 1224
+V + V P S + A ++ VSW+++ Y I NG + E
Sbjct: 988 NVVGRTV-PASVQGVIADNAYSSYSLI-VSWQKAAGV-AERYDILLLTENGILLRNTSEP 1044
Query: 1225 VHADQSSCTFDNLSPGLEYNVSVYTVKD---DKESVPISDTIIPAVPPPTDLRFTNIGPD 1281
Q F++L+PG +Y + + TV KE+ T+ AV TDLR T
Sbjct: 1045 ATTKQHK--FEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAV---TDLRITENSTR 1099
Query: 1282 TMRVTW-APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY-VVSVS 1339
+ W A + N + Y+P N ++ A+ + P + NLL G Y +V V+
Sbjct: 1100 HLSFRWTASEGELSWYNIFL-YNPDGNLQERAQ--VDPLVQSFSFQNLLQGRMYKMVIVT 1156
Query: 1340 SVYEQHESTPLRGRQ-KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYR-IRHHPEHF 1397
E + + GR + G + + T +S +W Y I ++P
Sbjct: 1157 HSGELSNESFIFGRTVPASVSHLRGSNRN--TTDSLWFNWSPASGDFDFYELILYNP--- 1211
Query: 1398 SGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVV 1457
+G +E+ L PG +YV+ +V +G + S + + T P +
Sbjct: 1212 NGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSG-DLSNKVTAESRTAPSPPSLMSFA 1270
Query: 1458 AATPTSLLISWDAPAVTVRY--YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYT 1515
TSL I+W P Y + + + + + S+ + GL+PG Y
Sbjct: 1271 DIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRI-VYGLRPGRSYQ 1329
Query: 1516 ITVYAVTGRGDS-PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRV 1574
V V+G DS SKPI + RT+ DK + +I+ W+P S GY +
Sbjct: 1330 FNVKTVSG--DSWKTYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSI 1387
Query: 1575 TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR 1634
+ ++ +++ + I L P Y+VS+ Q+ S+ + + +T IDR
Sbjct: 1388 ECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDR 1447
Query: 1635 P-----------KGLAFTDVDVD-SIKIAWESPQGQVSRYRVTYSSPEDGIHELFP 1678
P K + + ++ ++ +W S +Y DG EL P
Sbjct: 1448 PPPPPPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKYFTVVVREADGSDELKP 1503
Score = 35.4 bits (80), Expect = 0.67
Identities = 37/194 (19%), Positives = 76/194 (39%), Gaps = 25/194 (12%)
Query: 628 IQWNAPQP-SHISKYILRWRPKNSV---GRWKEATIPGHLNSYTIKGLKPGVVYEGQLIS 683
I W P + + + L+W P++++ + G + + GL+PG Y+ + +
Sbjct: 1279 ITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRI----VYGLRPGRSYQFNVKT 1334
Query: 684 IQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSA 743
+ + ++ F + T N L ++ T I S W+
Sbjct: 1335 VSGDSWKTYSKPIFGSVRTKPDKIQN-----------LHCRPQNSTAIACS-----WIPP 1378
Query: 744 SDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLIL 803
G+ +E + + L + +NI L+P ++Y+V++ ++ G S ++
Sbjct: 1379 DSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSI-KVQSAGMTSEVV 1437
Query: 804 STSQTTAPDAPPDP 817
S T D PP P
Sbjct: 1438 EDSTITMIDRPPPP 1451
>gi|112734845 collagen, type XX, alpha 1 [Homo sapiens]
Length = 1284
Score = 155 bits (392), Expect = 4e-37
Identities = 147/533 (27%), Positives = 232/533 (43%), Gaps = 31/533 (5%)
Query: 1115 FKLGVRPSQGGEA------PREVTSDSG-SIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167
F +GV+ + E PR++T S + G G+ Q L+ G R P
Sbjct: 311 FAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLICQRLQGGSPRQGPAA 370
Query: 1168 NKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
+ L PT+L L + + +SW + + Y I + G G E VV
Sbjct: 371 APALDTLPAPTSLVLSQVTSSSI-RLSWTPAPRHPLK-YLIVWRASRG--GTPREVVVEG 426
Query: 1228 DQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPA-VPPPTDLRFTNIGPDTMRVT 1286
+S NL+ EY VSV+ + + + + A +PPP L + P T+ +T
Sbjct: 427 PAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLT 486
Query: 1287 WAPPPSIDLTNFLVRYSPV--KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-- 1342
W P S T++LVR SP K EE+ E+ + + V+L L PG +Y VSV S+
Sbjct: 487 WQP--SAGATHYLVRCSPASPKGEEEEREVQVGRPE--VLLDGLEPGRDYEVSVQSLRGP 542
Query: 1343 EQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPR 1402
E E+ +R R T L P + FSD++ ++ V W + R+ + G
Sbjct: 543 EGSEARGIRARTPT-LAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSE-GGHSG 600
Query: 1403 EDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV-SDVPRDLEVVAATP 1461
+ P + S TL L+ T Y V + L S L G+ +T + P L +
Sbjct: 601 QTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPG 660
Query: 1462 TSLLISWDAPAVT-VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
++ ++W A A + V Y+IT+ G E +VPG+ TA + GL +Y +T+ A
Sbjct: 661 DAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRHTEYDVTILA 719
Query: 1521 VTGRGDSPASSKPISINYRTEI---DKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577
G A S P+S+ Y PS + + +S+ V W P V Y +T
Sbjct: 720 YYRDG---ARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYA 776
Query: 1578 PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT 1630
P +G GP K+ + ++ +T+ LQ +Y V V A +G S+ + T T
Sbjct: 777 PASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829
Score = 146 bits (369), Expect = 2e-34
Identities = 133/449 (29%), Positives = 203/449 (45%), Gaps = 22/449 (4%)
Query: 1358 LDSPTGIDFSDITANSFTVHWI-APRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT 1416
L +PT + S +T++S + W APR + Y I G PRE V S L
Sbjct: 377 LPAPTSLVLSQVTSSSIRLSWTPAPRHPLK-YLIVWRASR-GGTPREVVVEGPAASTELH 434
Query: 1417 NLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVTV 1475
NL TEY+VS+ + L G +T PR L + A TP ++ ++W P+
Sbjct: 435 NLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQ-PSAGA 493
Query: 1476 RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPIS 1535
+Y + +E V + + GL+PG DY ++V ++ G P S+
Sbjct: 494 THYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG----PEGSEARG 549
Query: 1536 INYRTE-IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594
I RT + P + +DV ++ V W + PV RVT G +T+ G +
Sbjct: 550 IRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPG-NA 608
Query: 1595 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTDVDVDSIKIAW- 1652
T T+ L + Y V V P G S L T P L+ T++ D++++AW
Sbjct: 609 TSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWV 668
Query: 1653 -ESPQGQVSRYRVTYSSPEDG-IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH-DDM 1709
+P G V Y++T++ +G HE+ + G TA L GL +EY V+++A + D
Sbjct: 669 AAAPSG-VLVYQITWTPLGEGKAHEI--SVPGNLGTAVLPGLGRHTEYDVTILAYYRDGA 725
Query: 1710 ESQP--LIGTQSTAIPAP-TDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMK 1766
S P L T ST +P ++L TP SL WTPP ++ Y + P GP K
Sbjct: 726 RSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEK 785
Query: 1767 EINLAPDSSSVVVSGLMVATKYEVSVYAL 1795
+++ S V + L ATKY V V A+
Sbjct: 786 SVSVPGARSHVTLPDLQAATKYRVLVSAI 814
Score = 145 bits (367), Expect = 4e-34
Identities = 139/474 (29%), Positives = 219/474 (46%), Gaps = 29/474 (6%)
Query: 1073 QESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGV--RPSQGGEAPRE 1130
++ P A TL +S+ ++VT ++I ++WTPAPR K + R S+GG PRE
Sbjct: 365 RQGPAAAPALDTLPAPTSL--VLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGG-TPRE 421
Query: 1131 VTSD--SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEA-NPD 1187
V + + S + L EY+ ++ + +G + PL PP L L A P
Sbjct: 422 VVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPR 481
Query: 1188 TGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV 1247
T LT W+ S T Y + +P + +G E V + D L PG +Y VSV
Sbjct: 482 TVHLT--WQPSA--GATHYLVRCSPAS-PKGEEEEREVQVGRPEVLLDGLEPGRDYEVSV 536
Query: 1248 YTVKDDKESVPISDTI-IPAVPPPTDLRFTNIGPDTMRVTW--APPPSIDLTNFLVRYSP 1304
+++ + S P + PP L F+++ D RV W AP P LVR +
Sbjct: 537 QSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVR-----LVRVTY 591
Query: 1305 VKNEEDVAELSISPSD-NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPT 1362
V +E + + +P + + L L T Y V V+ +Y S+ L GR T SP+
Sbjct: 592 VSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPS 651
Query: 1363 GIDFSDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPG 1421
+ +++ ++ + W+A + + Y+I P G+ E VP + + L L
Sbjct: 652 QLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRH 710
Query: 1422 TEYVVSIVAL--NGREESPLLIGQQ-STVS-DVPRDLEVVAATPTSLLISWDAPAVTVRY 1477
TEY V+I+A +G P+ + STVS P +L + + TP SL +SW P V +
Sbjct: 711 TEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLH 770
Query: 1478 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS 1531
Y +TY G P + +VPG++S T+ L+ Y + V A+ G S A S
Sbjct: 771 YWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVS 824
Score = 127 bits (320), Expect = 1e-28
Identities = 118/470 (25%), Positives = 195/470 (41%), Gaps = 23/470 (4%)
Query: 988 PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
P A L APT+L T S++ + WTP Y + +R G PR+ V
Sbjct: 368 PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGP 427
Query: 1048 VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN----TEVTETTI 1103
+ L NL +EY VS+ I G+ TT + +PP VT T+
Sbjct: 428 AASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTT----APLPPPRALTLAAVTPRTV 483
Query: 1104 VITWTP---APRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQ 1160
+TW P A + +G E REV +++ GL PG +Y ++Q LR +
Sbjct: 484 HLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPE 543
Query: 1161 ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNS 1220
+A + L+PP +L ++ V WE + P + R+T + G G+S
Sbjct: 544 GSEARGIRARTPTLAPPRHLGF-SDVSHDAARVFWEGAPRP-VRLVRVTYVSSEG--GHS 599
Query: 1221 LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTI-IPAVPPPTDLRFTNIG 1279
+ + +S T LS Y V V + S ++ + P P+ L T +
Sbjct: 600 GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELP 659
Query: 1280 PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS 1339
D +++ W + + + ++P+ E E+S+ + VL L TEY V++
Sbjct: 660 GDAVQLAWVAAAPSGVLVYQITWTPL-GEGKAHEISVPGNLGTAVLPGLGRHTEYDVTIL 718
Query: 1340 SVYE---QHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPE 1395
+ Y + + LR T P+ + + T +S V W P + Y + + P
Sbjct: 719 AYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPA 778
Query: 1396 HFSGRPREDRVPHSRNSITLTNLTPGTEY--VVSIVALNGREESPLLIGQ 1443
G + VP +R+ +TL +L T+Y +VS + GR E+ GQ
Sbjct: 779 SGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQ 828
Score = 114 bits (286), Expect = 9e-25
Identities = 129/516 (25%), Positives = 215/516 (41%), Gaps = 41/516 (7%)
Query: 1524 RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPG 1583
+G SP P + + P+ + ++ V +SI + W P+ Y + G
Sbjct: 360 QGGSPRQG-PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGT 418
Query: 1584 PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTD 1642
P + GP + L EY+VSV+ G + L T + P+ L
Sbjct: 419 PREVVVEGP-AASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAA 477
Query: 1643 VDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQ---------GLR 1693
V ++ + W+ P + Y V S +P GEE+ E+Q GL
Sbjct: 478 VTPRTVHLTWQ-PSAGATHYLVRCSPA---------SPKGEEEEREVQVGRPEVLLDGLE 527
Query: 1694 PGSEYTVSVVALHDDMESQPL-IGTQSTAIPAPTDLKFTQVTPTSLSAQW--TPPNVQLT 1750
PG +Y VSV +L S+ I ++ + P L F+ V+ + W P V+L
Sbjct: 528 PGRDYEVSVQSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRL- 586
Query: 1751 GYRVRVTPKEKTGPMKEINLAP-DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT 1809
VRVT G AP +++S + L +T Y V V L S G VT
Sbjct: 587 ---VRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVT 643
Query: 1810 TLENVSPPRRARVTDATETTITISWRTKTET-ITGFQVDAVPANGQTPIQRTIKPDVRSY 1868
T + SP + + +T+ + ++W + + +Q+ P + ++ ++ +
Sbjct: 644 TKKAPSPSQLS-MTELPGDAVQLAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTA 702
Query: 1869 TITGLQPGTDYKIYLYTL-NDNARSSPVVI---DASTAIDAPSNLRFLATTPNSLLVSWQ 1924
+ GL T+Y + + D ARS PV + ++ + PSNL + TP+SL VSW
Sbjct: 703 VLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWT 762
Query: 1925 PPRARITGYIIKY-EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 1983
PP R+ Y + Y G P + V P + T+ L+ T+Y + V A+ +SE
Sbjct: 763 PPLGRVLHYWLTYAPASGLGPEKSVSVP-GARSHVTLPDLQAATKYRVLVSAIYAAGRSE 821
Query: 1984 PLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQK 2019
+ +T P L P +L G +++ S V+K
Sbjct: 822 AVSATGQT-ACPAL--RPDGSLPGFDLMVAFSLVEK 854
Score = 104 bits (259), Expect = 1e-21
Identities = 112/475 (23%), Positives = 200/475 (42%), Gaps = 23/475 (4%)
Query: 895 QQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRL 954
+Q P DT+P+P L +VT + + WTP Y + V + G + +
Sbjct: 365 RQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLI-VWRASRGGTPREVV 423
Query: 955 PISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT-KLDAPTNLQFVNETDSTV 1013
E+ L+ Y VF + G + L TT L P L T TV
Sbjct: 424 VEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTV 483
Query: 1014 LVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGN 1072
+ W P A T Y + + +G+ + V + L L+P +Y VS+ +++G
Sbjct: 484 HLTW-QPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG- 541
Query: 1073 QESPKATGVFTTLQPGSSIPPYN---TEVTETTIVITWTPAPRIGFKLGVR--PSQGGEA 1127
E +A G+ + + PP + ++V+ + W APR + V S+GG +
Sbjct: 542 PEGSEARGI--RARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHS 599
Query: 1128 PR-EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSP-PTNLHLEAN 1185
+ E ++ S + L+ Y + L G + + +V T +P P+ L +
Sbjct: 600 GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG-GGSSTLTGRVTTKKAPSPSQLSMTEL 658
Query: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
P V ++W + + Y+IT TP +G + E V + + L EY+V
Sbjct: 659 PGDAV-QLAWVAAAPSGVLVYQITWTPLG--EGKAHEISVPGNLGTAVLPGLGRHTEYDV 715
Query: 1246 SVYT-VKDDKESVPISDTIIPAV---PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301
++ +D S P+S P+ PP++L + PD+++V+W PP + ++ +
Sbjct: 716 TILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLG-RVLHYWLT 774
Query: 1302 YSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT 1356
Y+P +S+ + + V L +L T+Y V VS++Y S + +T
Sbjct: 775 YAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829
Score = 102 bits (255), Expect = 3e-21
Identities = 130/522 (24%), Positives = 196/522 (37%), Gaps = 52/522 (9%)
Query: 599 CQPLQTYPSSSGPVEVFITETPSQP----------NSHPIQWNAPQPSHISKYILRWRPK 648
CQ LQ GP +T P +S + W P P H KY++ WR
Sbjct: 356 CQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWT-PAPRHPLKYLIVWRAS 414
Query: 649 NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708
G +E + G S + L Y + I + G E R TT+ P
Sbjct: 415 RG-GTPREVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLR-GLVTTAPLPP--- 469
Query: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768
P T +VT T ++W S + + V + E + ++
Sbjct: 470 -----------PRALTLAAVTPRTVH---LTW-QPSAGATHYLVRCSPASPKGEEEEREV 514
Query: 769 PSTATSVNIPDLLPGRKYIVNVYQI--SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTS 826
V + L PGR Y V+V + E E I + + T AP P V +
Sbjct: 515 QVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAP--PRHLGFSDVSHDA 572
Query: 827 IVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN 886
V W P+ R+ Y S G S + P A S TL L Y + + +
Sbjct: 573 ARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG 632
Query: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMW-TPPESAVTGYRVDVIPVN 945
S+ + TG + PSP L E+ V + W S V Y++ P+
Sbjct: 633 GGSSTL------TGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLG 686
Query: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-VSHGRESKPLTAQ---QTTKLDAPT 1001
H +P + T A + GL Y + A G S P++ + T P+
Sbjct: 687 EGKAHEISVPGNLGT-AVLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPS 745
Query: 1002 NLQFVNETDSTVLVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060
NL +ET ++ V WTPP ++ Y LT + G + +V + S L +LQ A+
Sbjct: 746 NLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAAT 805
Query: 1061 EYTVSLVAI--KGNQESPKATG--VFTTLQPGSSIPPYNTEV 1098
+Y V + AI G E+ ATG L+P S+P ++ V
Sbjct: 806 KYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFDLMV 847
Score = 74.7 bits (182), Expect = 1e-12
Identities = 92/414 (22%), Positives = 159/414 (38%), Gaps = 34/414 (8%)
Query: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSH-ISKYILRWRPK 648
Y G+GE + T P P +T P + + W QPS + Y++R P
Sbjct: 450 YEGGVGEGLRGLVTTAPL---PPPRALTLAAVTPRTVHLTW---QPSAGATHYLVRCSPA 503
Query: 649 NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708
+ G +E + + GL+PG YE + S++ E T + + P
Sbjct: 504 SPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAPP--- 560
Query: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768
++++ + V W A V RV Y SE G Q +
Sbjct: 561 ---------------RHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQ-TEA 604
Query: 769 PSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828
P ATS + L Y V V + G S + T +P ++ ++ ++
Sbjct: 605 PGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQ 664
Query: 829 VRW-SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA-VEEN 886
+ W + + + Y+I ++P EG + E+++P + L L +Y++TI A +
Sbjct: 665 LAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDG 724
Query: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN- 945
S PV ++ TP + + P +L T + + WTPP V Y + P +
Sbjct: 725 ARSDPVSLRY----TPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASG 780
Query: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA 999
L E +P +R + + L Y V A+ S+ ++A T A
Sbjct: 781 LGPEKSVSVPGAR-SHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPA 833
Score = 65.5 bits (158), Expect = 6e-10
Identities = 66/271 (24%), Positives = 113/271 (41%), Gaps = 23/271 (8%)
Query: 604 TYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHL 663
T + P ++ +TE P ++ + W A PS + Y + W P G+ E ++PG+L
Sbjct: 643 TTKKAPSPSQLSMTELPG--DAVQLAWVAAAPSGVLVYQITWTPLGE-GKAHEISVPGNL 699
Query: 664 NSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVA 723
+ + GL Y+ +++ + G + + S T +TV+ +P S L
Sbjct: 700 GTAVLPGLGRHTEYDVTILAYYRDGAR--------SDPVSLRYTPSTVS--RSPPSNLAL 749
Query: 724 TSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
SE T S VSW V + + Y + + + +P + V +PDL
Sbjct: 750 ASE-----TPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAA 804
Query: 784 RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYR- 842
KY V V I G + +T QT P PD ++ D ++V +S + R
Sbjct: 805 TKYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFD---LMVAFSLVEKAYASIRG 861
Query: 843 IVYSPSVEGSSTELNLPETAN-SVTLSDLQP 872
+ PS G + L + A + +SD+ P
Sbjct: 862 VAMEPSAFGGTPTFTLFKDAQLTRRVSDVYP 892
Score = 34.3 bits (77), Expect = 1.5
Identities = 20/83 (24%), Positives = 35/83 (42%), Gaps = 2/83 (2%)
Query: 2073 PRPYPPNVGQEALSQTTI--SWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTG 2130
P P P + A++ T+ +W P + Y++ C P E + V L G
Sbjct: 466 PLPPPRALTLAAVTPRTVHLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDG 525
Query: 2131 LTRGATYNIIVEALKDQQRHKVR 2153
L G Y + V++L+ + + R
Sbjct: 526 LEPGRDYEVSVQSLRGPEGSEAR 548
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 154 bits (388), Expect = 1e-36
Identities = 299/1365 (21%), Positives = 509/1365 (37%), Gaps = 169/1365 (12%)
Query: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPI-QWNAPQP---SHISKYILRW 645
YG G+ +P+ S + P I E H I QW P+ + IS Y++
Sbjct: 29220 YGPGVPV-ESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDK 29278
Query: 646 RPKNSVGRWKEATIPGHLNSYTIK--GLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTS 703
R K S+ RW + +K L G Y+ ++ ++ G+ E +
Sbjct: 29279 REKKSL-RWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSE--------- 29328
Query: 704 TPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELS-EEGDE 762
SN ++ ++P ++ V + T S ++W V Y L +E D
Sbjct: 29329 ---ASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDT 29385
Query: 763 PQYLDLPSTATSVN----IPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT 818
Q+ + + AT N +PDL G+KY V ++ G S ++ + P
Sbjct: 29386 DQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPD 29445
Query: 819 VDQVDDT--SIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP-----ETANSVTLSDLQ 871
++ DD ++ +R + P + S ++L +T S +L +
Sbjct: 29446 LELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVD 29505
Query: 872 PGVQYNITIYAVE-ENQE----STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
+Y+ Y +E ENQ +T +V +T G P P ++ EV+ VTI
Sbjct: 29506 KVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPG-------PCP-SVKVKEVSRDSVTIT 29557
Query: 927 WTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH 982
W P + V Y V+ + S+ T ++GL G YYF+V +
Sbjct: 29558 WEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSK-TLYRISGLVEGTMYYFRVLPENI 29616
Query: 983 GRESKPLTAQQTTKLD----APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLT 1034
+P + P L+ V+ T STV + W P +++TGY L
Sbjct: 29617 YGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEA--C 29674
Query: 1035 RRGQPRQYNV---GPSVSKYPLRNLQPASEYTVSLVAI--KGNQESPKATGVFTTLQPGS 1089
+ G R V P+V ++ + +L +Y + A KG E P+ T T+Q
Sbjct: 29675 KAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSE-PRETVTAVTVQDLR 29733
Query: 1090 SIPPYNTEV-------------TETTIVITWTPAPRIG-FKLGVRPSQGGEAPREVTSDS 1135
+P + E I I P P F G + + E +
Sbjct: 29734 VLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKV 29793
Query: 1136 GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
+ + T YT+++ I ++ PPT D +T+SW
Sbjct: 29794 AKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISW 29853
Query: 1196 ERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV----- 1247
E ++GY + + + E V +S+ F L+ G EY V
Sbjct: 29854 EPPELDGGAPLSGYVVEQRDAHRPGWLPVSESV--TRSTFKFTRLTEGNEYVFRVAATNR 29911
Query: 1248 YTVKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYS 1303
+ + +S I +P PP L+ ++ D M +TW PP +T ++V
Sbjct: 29912 FGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERK 29971
Query: 1304 PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR-GRQKTGLD--- 1359
V+ + V + + T L G EY V+++ + P R + +D
Sbjct: 29972 EVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIA 30031
Query: 1360 ---SPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNS 1412
P +D T S ++ W P + +TGY I + + P
Sbjct: 30032 PPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIRE 30091
Query: 1413 ITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAAT--PTSLLISWDA 1470
TLT+L G EY ++A N G ++VP ++V P L
Sbjct: 30092 YTLTHLPQGAEYRFRVLACNA--------GGPGEPAEVPGTVKVTEMLEYPDYELDERYQ 30143
Query: 1471 PAVTVRY---YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
+ VR R+T G P+ ++T G + + + + +T V RGDS
Sbjct: 30144 EGIFVRQGGVIRLTIPIKGKPFPICKWTKEG-QDISKRAMIATSETHTELVIKEADRGDS 30202
Query: 1528 ---------PASSKPISINYRTEIDKPSQ----MQVTDVQDNSISVKWLPSS----SPVT 1570
K + I R I P+ ++ D+Q S+ V W P + + +
Sbjct: 30203 GTYDLVLENKCGKKAVYIKVRV-IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADIL 30261
Query: 1571 GYRVTT--TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ-- 1626
GY + PK ++ G T + ++GL+ VEY V A+N G S+PL
Sbjct: 30262 GYILERREVPKAAWYTIDSRVRG---TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEE 30318
Query: 1627 --TAVTNIDRPKGLA----FTDVDVDSIKIAWESPQGQ-VSRYRVTYSSPEDGIHELFPA 1679
T T ++ P+ + DV S+ ++W P+ SR Y ++ + +
Sbjct: 30319 PVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVR 30378
Query: 1680 PDGEEDTAEL---QGLRPGSEYTVSVVALHD------DMESQPLIGTQSTAIPA-PTDLK 1729
+ + T + GL P +EY ++A +D S+P++ P+ P +L+
Sbjct: 30379 HNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELE 30438
Query: 1730 FTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVA 1785
++ S++ QW P ++ GY V + K + GL+ A
Sbjct: 30439 ILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEA 30498
Query: 1786 TKYEVSVYALKDTLTSRP---AQGVVTTL-ENVSPPRRARVTDAT 1826
T+YE V+A +T SRP A + T L +P R + D T
Sbjct: 30499 TEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVT 30543
Score = 148 bits (373), Expect = 7e-35
Identities = 289/1429 (20%), Positives = 524/1429 (36%), Gaps = 170/1429 (11%)
Query: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
D+T T+ ++ + + P S + ++ + ++SW + Y
Sbjct: 19365 DYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 19424
Query: 756 LSE-EGDEPQYLDLPSTA--TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQ 807
+ + E P + + +T TS ++ L+ G +Y N Y + + ++ +
Sbjct: 19425 VDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNP 19484
Query: 808 TTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNL-PETA 862
P P + + + V W P +PITGY + + + T++N P
Sbjct: 19485 YDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIE 19544
Query: 863 NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK 922
++ + LQ G +Y + A+ + P + P + + T
Sbjct: 19545 RTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSS 19604
Query: 923 VTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKV 977
V++ W P S + GY V+V + LP + + T EVTGL Y F+V
Sbjct: 19605 VSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRV 19664
Query: 978 FAVSHGRESKP-----------LTAQQTTKLDAPTNLQFVNETDST----VLVRWTPPRA 1022
+AV+ S P + +LDA + T V V+ PP
Sbjct: 19665 YAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPP-P 19723
Query: 1023 QITGYRLTVGLTRR-GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
+IT + V L R G + + + N A +Y ++L G +E V
Sbjct: 19724 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 19783
Query: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDS 1135
T PG + E+++ + +TW P +P I + + R ++ T S
Sbjct: 19784 LDT--PGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECS 19841
Query: 1136 G-SIVVSGLTPGVEYVYTIQVLRD------GQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
S V+ L G Y + + + G+ RDA V TP P +L + + +
Sbjct: 19842 KTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDA--VKASQTP-GPVVDLKVRSVSKS 19898
Query: 1189 GVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
++ W++ + I GY + + N + V+ + + +L+ G EY
Sbjct: 19899 SC-SIGWKKPHSDGGSRIIGYVVDFLT----EENKWQRVMKSLSLQYSAKDLTEGKEYTF 19953
Query: 1246 SVYTVKDDKESVPISDTIIP---AVPPPTDLRFTNIGPDT-------------MRVTWAP 1289
V ++ E P T++ V P DL+ PD + + P
Sbjct: 19954 RVSAENENGEGTPSEITVVARDDVVAPDLDLKGL---PDLCYLAKENSNFRLKIPIKGKP 20010
Query: 1290 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL-------PGTEYVVSVSSVY 1342
PS+ S K E+ +A + +++ V T L+ +Y +++ +V
Sbjct: 20011 APSV---------SWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVA 20061
Query: 1343 EQHEST-PLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEH 1396
E T ++ K G+ PTG I F ++TA + T+ W P+ + IT Y I +
Sbjct: 20062 GTKEGTISIKVVGKPGI--PTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNY-ILEKRDS 20118
Query: 1397 FSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------GREESPLLIGQQSTVSDV 1450
+ + + + +T L G EY + A N G + P++ V D
Sbjct: 20119 VNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDA 20178
Query: 1451 PRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATIS 1506
P +V S+ ++W P T + Y + + E + P ++
Sbjct: 20179 PPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVT 20238
Query: 1507 GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP-- 1564
GL G++Y V A+ G S + ID P + +V ++ NS+++ W
Sbjct: 20239 GLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPK 20298
Query: 1565 --SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1622
+TGY V K + T+ L +Y + A+N +G
Sbjct: 20299 YDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAIS 20358
Query: 1623 PLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQV----------------SRYRVTY 1666
++ T I + + A T V +IK G S +
Sbjct: 20359 APSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGK 20418
Query: 1667 SSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT 1726
I ++ P T + + EYT++ + P P
Sbjct: 20419 DIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGP-PG 20477
Query: 1727 DLKFTQVTPTSLSAQWTPPNVQLTGYRVR--VTPKEKTGPMKEINLAPDSSSV--VVSGL 1782
++ + V+ + WTPP ++ G ++ + K +T + ++ D S V + L
Sbjct: 20478 PVEISNVSAEKATLTWTPP-LEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKL 20536
Query: 1783 MVATKYEVSVYALKDTLTSRPAQG----VVTTLENVSPPRRARVTDATETTITISWRTKT 1838
+ +Y V A+ P Q +V PP + V++ T+ T T+SW+
Sbjct: 20537 IQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPV 20596
Query: 1839 E----TITGFQVDAVPANGQTPIQRTIKPDVRSY--TITGLQPGTDYKIYLYTLN----- 1887
+ ITG+ V+ + R IK V +TGLQ G+ Y+ + N
Sbjct: 20597 DDGGSEITGYHVERREKKSLRWV-RAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 20655
Query: 1888 --DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPG 1941
A S ++ DA+ PSN TT S ++W P ITGY+++++K G
Sbjct: 20656 PPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVG 20715
Query: 1942 SPPREVVPRPRPG----VTEATITGLEPGTEYTIYVIALKNNQKSEPLI 1986
E + G +T+ + L+ +Y + A+ + EP +
Sbjct: 20716 D---EAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAV 20761
Score = 145 bits (367), Expect = 4e-34
Identities = 292/1351 (21%), Positives = 505/1351 (37%), Gaps = 184/1351 (13%)
Query: 780 LLPGRKYIVNVYQISEDG-----EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP 834
L+ +YI V +++ G E I++ + T P P P I+++W++P
Sbjct: 29204 LIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKP 29263
Query: 835 QAP----ITGYRIVYSPSVEGSSTELNLPETANSVTL--SDLQPGVQYNITIYAVEENQE 888
++ I+ Y + T +N L + L G Y + AV
Sbjct: 29264 ESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGN 29323
Query: 889 STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
S P + S T P + V+ T +++ WT P + + GY +++
Sbjct: 29324 SEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEK 29383
Query: 945 NLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA----QQTTKLDA 999
+ + + RNT V L G Y F+V AV+ S+ + + +++
Sbjct: 29384 DTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEI 29443
Query: 1000 PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP-----------RQYNVGPSV 1048
P +L+ ++ TV +R RL V ++ R P + +
Sbjct: 29444 P-DLELADDLKKTVTIRAG------ASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTT 29496
Query: 1049 SKYPLR-----NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI 1103
Y L N A +YT+ G + + V+ T P S+ EV+ ++
Sbjct: 29497 ESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKV--KEVSRDSV 29554
Query: 1104 VITWT------PAPRIGFKLGVRPSQGGEAPREVTSDSGSIV-VSGLTPGVEYVYTIQ-- 1154
ITW AP + + R + T S ++ +SGL G Y + +
Sbjct: 29555 TITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPE 29614
Query: 1155 ----VLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYR 1207
+ + DA +V++V PL P ++ T +T++WE+ +TGY
Sbjct: 29615 NIYGIGEPCETSDAVLVSEV--PLVPAKLEVVDVTKST--VTLAWEKPLYDGGSRLTGYV 29670
Query: 1208 ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY-----------------NVSVYTV 1250
+ ++ + + T +L+ G +Y V+ TV
Sbjct: 29671 LEACKAGTERWMKVV-TLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTV 29729
Query: 1251 KD-------DKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYS 1303
+D D ++P +PA P +L + + PPP+ F
Sbjct: 29730 QDLRVLPTIDLSTMPQKTIHVPA-GRPVEL--------VIPIAGRPPPAASW--FFAGSK 29778
Query: 1304 PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHESTPLRGRQKTGLDSPT 1362
++E E + + T + EY + + +V E+ + K G PT
Sbjct: 29779 LRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPG--PPT 29836
Query: 1363 G-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSG-RPREDRVPHSRNSITLT 1416
G I +I A S T+ W P A ++GY + H G P + V +R++ T
Sbjct: 29837 GPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESV--TRSTFKFT 29894
Query: 1417 NLTPGTEYVVSIVALN----GREESPLLIGQQSTVS--DVPRDLEVVAATPTSLLISWDA 1470
LT G EYV + A N G +I +S++ P L++ + + ++W
Sbjct: 29895 RLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYP 29954
Query: 1471 P----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD 1526
P V Y + E + V+ VP + + +GL G++Y V A+ RG
Sbjct: 29955 PEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGS 30014
Query: 1527 SPAS--SKPI-SINYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPK 1579
S SKPI +++ KP +VTD S+S+ W S VTGY +
Sbjct: 30015 GKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKV 30074
Query: 1580 NGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLA 1639
+ TK T E T+ L EY V A N G +P + L
Sbjct: 30075 DQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEM--LE 30132
Query: 1640 FTDVDVDS-IKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEY 1698
+ D ++D + QG V R + I + +G+ D ++ + +
Sbjct: 30133 YPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKW--TKEGQ-DISKRAMIATSETH 30189
Query: 1699 TVSVVALHDDMES------------QPLIGTQSTAIPAPTD----LKFTQVTPTSLSAQW 1742
T V+ D +S + + + I +P L++ + S+ W
Sbjct: 30190 TELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSW 30249
Query: 1743 TPP----NVQLTGYRV--RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1796
PP + GY + R PK I+ +S+VV GL +Y V A
Sbjct: 30250 RPPADDGGADILGYILERREVPK---AAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAEN 30306
Query: 1797 DTLTSRP--AQGVVTTLENVSPPRRA----RVTDATETTITISW-RTKTE---TITGFQV 1846
S+P ++ VT ++PP V D T++++++SW R K + +TG+ +
Sbjct: 30307 QFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYI 30366
Query: 1847 DAVPANGQTPIQRTIKPDVRS--YTITGLQPGTDYKIYLYTLND------NARSSPVVI- 1897
+ + ++ K + + YT+TGL P +Y+ + ND + S PVV
Sbjct: 30367 ERKETSTDKWVRHN-KTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCK 30425
Query: 1898 DASTAIDAPSNLRFLATTPNSLLVSWQPPRA----RITGYIIKYEKPGSPPREVVPRPRP 1953
D P L L+ + +S+ + W+ P I GY ++Y + G + + R
Sbjct: 30426 DPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERI 30485
Query: 1954 GVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
+ TI GL TEY V A S P
Sbjct: 30486 KDKQFTIGGLLEATEYEFRVFAENETGLSRP 30516
Score = 135 bits (339), Expect = 6e-31
Identities = 320/1486 (21%), Positives = 522/1486 (35%), Gaps = 215/1486 (14%)
Query: 771 TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVR 830
T S++ D KYI+ + S G +S ++ P P + V +V S +
Sbjct: 24078 TQLSIDNCDRNDAGKYILKLENSS--GSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLV 24135
Query: 831 WSRP----QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN 886
W P A + Y I S + ++ + S + +L G Y + A E
Sbjct: 24136 WEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEF 24195
Query: 887 QESTPVVIQQETTGTPRSDTVPSPRD-LQFVEVTDVKVTIMWTPPE----SAVTGYRVDV 941
PV ET ++ PSP + +V+ ++MW PE S V GY V++
Sbjct: 24196 GVGVPV----ETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEM 24251
Query: 942 IPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-----------LT 990
P E + S+ A VTGLS G Y F+V A + +S P LT
Sbjct: 24252 QPKGT--EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLT 24309
Query: 991 AQQTTKLDAPT-NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP----RQYNVG 1045
Q + KL T ++Q + + V P R + + G+P + NV
Sbjct: 24310 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRP--------RPNISWVKDGEPLKQTTRVNVE 24361
Query: 1046 PSVSKYPLR----NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN-TEVTE 1100
+ + L N +YTV+ G + + V +PG + P EV+
Sbjct: 24362 ETATSTVLHIKEGNKDDFGKYTVTATNSAGT--ATENLSVIVLEKPGPPVGPVRFDEVSA 24419
Query: 1101 TTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYV 1150
+VI+W P G G + S R+ T+ + +V ++ L G EY
Sbjct: 24420 DFVVISWEPPAYTG---GCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQ 24476
Query: 1151 YTIQVLRDGQERDAPIVNKVVTPLSP-----PTNLHLEANPDTGVLTVSWERSTTPD--- 1202
+ I + + AP+ +K V P P + + V W
Sbjct: 24477 FRI-FAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTK 24535
Query: 1203 ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN--VSVYTVKDDKESVPIS 1260
I GY + N L + D T L GLEY VS + + +S
Sbjct: 24536 IIGYHLEQKEKNSILWVKLNKTPIQDTKFKT-TGLDEGLEYEFKVSAENIVGIGKPSKVS 24594
Query: 1261 DTIIPAVP--PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELS 1315
+ + P PP I + + + W P +T ++V K+ D +
Sbjct: 24595 ECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEK---KDLPDGRWMK 24651
Query: 1316 ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFT 1375
S TN+L TE+ VS V +Q + R G S ITA
Sbjct: 24652 AS-------FTNVLE-TEFTVS-GLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARD-- 24700
Query: 1376 VHWIAPRATITG-YR---IRHHPEHF------SGRPREDRV--------------PHSRN 1411
AP A++ Y+ + H E F G+P D V ++
Sbjct: 24701 -EIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKS 24759
Query: 1412 SITLTNL-------TPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSL 1464
+I T L T G +Y++ + + G + P+ + L+V T
Sbjct: 24760 TIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKC 24819
Query: 1465 LISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
++W+ P + +Y I ET S Q T + + ++ L PG +Y V A
Sbjct: 24820 YLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYK-VTKLLPGNEYIFRVMA 24878
Query: 1521 VTGRG-DSPASSKPISI-NYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRV 1574
V G P S P++ N PS +V+ + +S+ V W + + GY +
Sbjct: 24879 VNKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYIL 24938
Query: 1575 TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT------- 1627
K G TK + + GL Y V A+N +G +P +
Sbjct: 24939 EKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACD 24998
Query: 1628 AVTNIDRPKGLAFTDVDVDSIKIAWESP----QGQVSRYRVTYSSPEDGIHELFPAPDGE 1683
A+ P TD S+ +AW P V Y V P G
Sbjct: 24999 ALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGL 25058
Query: 1684 EDTA-ELQGLRPGSEYTVSVVALHDDMESQPL-----IGTQSTAIPAPTDLKFTQVTPTS 1737
+ + L+ +EY + A++ + +P + Q P +L
Sbjct: 25059 QGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVV 25118
Query: 1738 LSAQWTPPNVQLTGYRVRVTPKEKTGPM----KEINLAPDSSSVVVSGLMV------ATK 1787
L A T R+ VT K + P K + D + + V+ T+
Sbjct: 25119 LRASAT--------LRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTR 25170
Query: 1788 YEVSVY--ALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETI 1841
++ Y L++ S+ A V L++ S P + + + ++T+SW I
Sbjct: 25171 FDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKI 25230
Query: 1842 TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1901
T + V+ + T ++ I LQ G Y + N+ P
Sbjct: 25231 TNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPV 25290
Query: 1902 AIDAP----SNLRFLATTPNSLLVSWQPPRA----RITGYIIKYEKPGSPPREVVPRPRP 1953
+ P + + T N+ + W+ P + +ITGY+++ + GS + +
Sbjct: 25291 KVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVK- 25349
Query: 1954 GVTEATITGLEPGTEYTIYVIALKNNQKSE------PLIGRKKTDELPQLVTLPHP--NL 2005
EATI+GL G EY V A+ +S+ P+I R E+ V LP N+
Sbjct: 25350 -TLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIAR--DIEIKPSVELPFHTFNV 25406
Query: 2006 HGPEIL--DVP---------------STVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQ 2048
E L DVP T+++T V T + + S + VG
Sbjct: 25407 KAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEAS--KEDVGT 25464
Query: 2049 QMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAP 2094
+ + T P T + P P + + + TISW P
Sbjct: 25465 YELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNP 25510
Score = 133 bits (334), Expect = 2e-30
Identities = 288/1457 (19%), Positives = 519/1457 (35%), Gaps = 224/1457 (15%)
Query: 728 VTEITASSFVVSWVSASDTVSGFRVEY--ELSEEGDEP-QYLDLPSTATSVNIPDLLPGR 784
V+ ++A S V+SW D Y E E G Q ++ T + + L
Sbjct: 28750 VSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYM 28809
Query: 785 KYIVNV-----YQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPIT 839
+Y V + +S+ E + I++ P AP P V V ++ +RW P
Sbjct: 28810 EYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGG 28869
Query: 840 GYRIVYSPSVEGSST-----ELNLPETANSVTLSDLQPGVQYNITIYAV------EENQE 888
I Y + +T E +P + ++ L G++Y YA+ + ++
Sbjct: 28870 SKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEA 28929
Query: 889 STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
S P++ Q + V +P + +VT V+++W+ P S V GY ++ PV
Sbjct: 28930 SRPIMAQ---------NPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPV 28980
Query: 945 NLPGEHGQRLP----ISRNTFAEVTGLSPGVTYYFKVFA------VSHGRESK-PLT--- 990
+ G+ G+ L I + F VT LS G TY F+V A +S G ES P+T
Sbjct: 28981 SEVGD-GRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRD 29039
Query: 991 --AQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR-------- 1040
A +LDA + V + LV A + G + +G
Sbjct: 29040 EYAPPKAELDARLHGDLVTIRAGSDLVL----DAAVGGKPEPKIIWTKGDKELDLCEKVS 29095
Query: 1041 -QYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTL--QPGSSIPPYNTE 1097
QY + + + + +YT+++ N KA V + PG +
Sbjct: 29096 LQYTGKRATAVIKFCDRSDSGKYTLTVK----NASGTKAVSVMVKVLDSPGPCGKLTVSR 29151
Query: 1098 VTETTIVITWTPAPRIGFKLGVRPSQGGEAP-------REVTSDSGSIVVSGLTPGVEYV 1150
VT+ + W+ P + G A R TS ++V G P + YV
Sbjct: 29152 VTQEKCTLAWS-----------LPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYV 29200
Query: 1151 YTIQVLRDGQE----------------RDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVS 1194
T +++++ + PIV + + P + E + +
Sbjct: 29201 VT-RLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQ 29259
Query: 1195 WERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK 1251
W + + +I+ Y + + + + + +L G +Y V V
Sbjct: 29260 WTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVN 29319
Query: 1252 DDKESVP--ISDTIIPAVP-----PPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSP 1304
S P S+ I P PP+ R + ++ + W P D +V Y
Sbjct: 29320 AAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKP-MYDGGTDIVGYVL 29378
Query: 1305 VKNEEDVAE-----LSISPSDNAVVLTNLLPGTEYVVSVSSV----YEQHESTPLRGRQK 1355
E+D + + + + + +L G +Y V++V ++ +
Sbjct: 29379 EMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPV 29438
Query: 1356 TGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP-------- 1407
++ P ++ +D + T+ A + R P + D
Sbjct: 29439 ERIEIPD-LELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTE 29497
Query: 1408 -HSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLI 1466
+S + N +Y + +G++ + +L+ T P ++V + S+ I
Sbjct: 29498 SYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCP-SVKVKEVSRDSVTI 29556
Query: 1467 SWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA-- 1520
+W+ P + V Y + E + + T SK+ ISGL G Y V
Sbjct: 29557 TWEIPTIDGGAPVNNYIVEKREAAMRA-FKTVTTKCSKTLYRISGLVEGTMYYFRVLPEN 29615
Query: 1521 VTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTT 1576
+ G G+ +S + ++ + P++++V DV +++++ W S +TGY +
Sbjct: 29616 IYGIGEPCETSDAVLVSEVPLV--PAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEA 29673
Query: 1577 TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPK 1636
K T P E T+ L +Y+ + AQN G S+P + +
Sbjct: 29674 CKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLR 29733
Query: 1637 GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDG--EEDTAELQGLRP 1694
L D+ K P G+ + + F A E + ++
Sbjct: 29734 VLPTIDLSTMPQKTI-HVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTK 29792
Query: 1695 GSEYTVSVVALHDD----MESQPLIGTQSTAI---------PAPTDLKFTQVTPTSLSAQ 1741
++ T+ + D +E + + GT S I P +K ++ TS++
Sbjct: 29793 VAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITIS 29852
Query: 1742 WTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1797
W PP + L+GY V + G + P S SV S E + Y +
Sbjct: 29853 WEPPELDGGAPLSGYVVEQRDAHRPGWL------PVSESVTRSTFKFTRLTEGNEYVFRV 29906
Query: 1798 TLTSRPAQGVVTTLENVS---------PPRRARVTDATETTITISWRTKTET----ITGF 1844
T+R G E + PP ++ D + +T++W + +TG+
Sbjct: 29907 AATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGY 29966
Query: 1845 QVDAVPANGQTPIQRTIKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSP-------VV 1896
V+ ++ P + Y TGL G +Y+ + +N P V
Sbjct: 29967 IVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVA 30026
Query: 1897 IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPR 1952
+D P N R TT S+ ++W P +++TGY+I+ +K
Sbjct: 30027 MDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTP 30086
Query: 1953 PGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILD 2012
+ E T+T L G EY V+A EP +
Sbjct: 30087 TKIREYTLTHLPQGAEYRFRVLACNAGGPGEP--------------------------AE 30120
Query: 2013 VPSTVQKTPFVTHPGYD 2029
VP TV+ T + +P Y+
Sbjct: 30121 VPGTVKVTEMLEYPDYE 30137
Score = 132 bits (332), Expect = 4e-30
Identities = 282/1282 (21%), Positives = 484/1282 (37%), Gaps = 198/1282 (15%)
Query: 611 PVEVFITETPSQPNSHPIQWNAP---QPSHISKYILRWRPKNSVGRWKEATIPGHLNSYT 667
PV V + E +S + W P S I Y+++ R W T S+
Sbjct: 19790 PVNVTVKEISK--DSAYVTWEPPIIDGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFR 19846
Query: 668 IKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSES 727
+ L+ G Y ++ + +YG + T + V TP P+V
Sbjct: 19847 VANLEEGKSYFFRVFAENEYGIGDPGE------------TRDAVKASQTP-GPVVDLK-- 19891
Query: 728 VTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
V ++ SS + W + G+ V++ L+EE + + S + + DL G
Sbjct: 19892 VRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMK--SLSLQYSAKDLTEG 19948
Query: 784 RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITG 840
++Y V +E+GE + T PD + + D + + + R + PI G
Sbjct: 19949 KEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKG 20008
Query: 841 YRIVYSPSVE--------GSSTELNLPETANSVTLS--DLQPGV--QYNITIYAVEENQE 888
+PSV + T +++ +A + TL D Q +Y IT+ V +E
Sbjct: 20009 KP---APSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 20065
Query: 889 STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
T I + G P T P ++F EVT +T+ W PP+ S +T Y ++
Sbjct: 20066 GT---ISIKVVGKPGIPTGP----IKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDS 20118
Query: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKL-D 998
+ + TF VT L G+ Y F+V + V G +S+P+ A+ + D
Sbjct: 20119 VNNKWVTCASAVQKTTF-RVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPD 20177
Query: 999 APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP-SVSKYPL 1053
AP V+ +V + WT P+ + ITGY L ++ N P + + +
Sbjct: 20178 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV 20237
Query: 1054 RNLQPASEYTVSLVAIK----GNQESPKATGVFTTLQPGSSIPPYNTEV---TETTIVIT 1106
L EY ++AI G P V L P PP EV T ++ +
Sbjct: 20238 TGLTEGLEYEFRVMAINLAGVGKPSLPSEPVV--ALDPID--PPGKPEVINITRNSVTLI 20293
Query: 1107 WT-PAPRIGFKLGVR-------PSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD 1158
WT P G KL PS+ V + V+ L G +Y + I+
Sbjct: 20294 WTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNT 20353
Query: 1159 GQERDAPIVN----------KVVTPLSPPT---NLHLEANPDTGVLTV-----------S 1194
AP + + T + PT L ++A DT VL S
Sbjct: 20354 AGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAG-DTIVLNAISILGKPLPKSS 20412
Query: 1195 WERS----TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
W ++ DIT +IT+TPT+ +++ D T +P + V V
Sbjct: 20413 WSKAGKDIRPSDIT--QITSTPTSSML--TIKYATRKDAGEYTITATNP---FGTKVEHV 20465
Query: 1251 KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEED 1310
K T++ PP + +N+ + +TW PP D + + Y K E
Sbjct: 20466 KV---------TVLDVPGPPGPVEISNVSAEKATLTWTPPLE-DGGSPIKSYILEKRETS 20515
Query: 1311 VAELSISPSDNAV---VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD------SP 1361
++ D V T L+ G EY+ VS+V + P++ +D P
Sbjct: 20516 RLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPP 20575
Query: 1362 TGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
+ S++T N+ TV W P + ITGY + + R + P S +T
Sbjct: 20576 EKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTG 20635
Query: 1418 LTPGTEYVVSIVALNGREESP-------LLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
L G+ Y + A N P +L+ + P + V T S ++W
Sbjct: 20636 LQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGK 20695
Query: 1471 P----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKPGVDYTITVYAVTGRG 1525
P + + Y + + + G + +++ T + T + L+ Y + A+ G
Sbjct: 20696 PHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAG 20755
Query: 1526 -DSPASSKPISINYR---TEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNG 1581
PA + I R + + ++++ T V +S++ VT T N
Sbjct: 20756 VGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNI 20815
Query: 1582 PGPTKTKTAGPDQTEMTIE---GLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRP-KG 1637
+ + + I T ++V+++ +NP+G+ V V + P
Sbjct: 20816 NLKNRANIENTESFTLLIIPECNRYDTGKFVMTI--ENPAGKKSGFVNVRVLDTPGPVLN 20873
Query: 1638 LAFTDVDVDSIKIAWESP----QGQVSRY--------RVTYSSPEDGIHELFPAPDGEED 1685
L TD+ DS+ + W+ P +++ Y R +YS+ H+
Sbjct: 20874 LRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKC--------- 20924
Query: 1686 TAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ---STAIPAPTD-LKFTQVTPTSLSAQ 1741
T ++ GL G EY V+A ++ +P T+ ++ P+P D L +T +++S
Sbjct: 20925 TYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLA 20984
Query: 1742 WTPP----NVQLTGYRVRVTPK 1759
W P ++TGY + K
Sbjct: 20985 WPKPKHDGGSKITGYVIEAQRK 21006
Score = 129 bits (324), Expect = 3e-29
Identities = 296/1415 (20%), Positives = 523/1415 (36%), Gaps = 202/1415 (14%)
Query: 728 VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT----SVNIPDLLPG 783
+ ++++ V W D G ++ + E+ + + + +AT + L+ G
Sbjct: 18305 IVDVSSDRCTVCWDPPEDD-GGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEG 18363
Query: 784 RKYIVNVYQISEDG-----EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ--- 835
+YI V ++ G E +++ ++ P P P V +V + V W+ P+
Sbjct: 18364 NEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDG 18423
Query: 836 -APITGYRIVYSPSVEGSSTELN---LPETANSVTLSDLQPGVQYNITIYAVEENQESTP 891
ITGY + +N +PE V +L P +Y + A E P
Sbjct: 18424 GKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKV--QNLLPDHEYQFRVKAENEIGIGEP 18481
Query: 892 VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNL- 946
+ + + P + + V+ T +T+ W P + + GY V++ P
Sbjct: 18482 SLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIAD 18541
Query: 947 --PGEHGQRL----PISRNTFAEVTGLSPGVTYYFKVFA---VSHGRESKPLTAQQTTKL 997
P E +R + R F VT L Y F+V A V GR ++ A + ++
Sbjct: 18542 ASPDEGWKRCNAAAQLVRKEFT-VTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEI 18600
Query: 998 DAPTNLQFVNETDSTVLVRWT-----------PPRAQITGYRLTV-GLTRRGQPRQYNVG 1045
P + V+VR P ++T ++ + + R+GQ +
Sbjct: 18601 LEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDT- 18659
Query: 1046 PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105
+ P + +Y+++LV G + V T P S + ++VT+T+ +
Sbjct: 18660 MAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKV--SDVTKTSCHV 18717
Query: 1106 TWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQV 1155
+W P G G + + RE + S V V+ L PG EY + +
Sbjct: 18718 SWAPPENDG---GSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTA 18774
Query: 1156 LRD---GQERDAPIVNKVVTPLS---PPTNLHLEANPDTGVLTVSWE---RSTTPDITGY 1206
+ + G D P PLS PP L + T++W R I GY
Sbjct: 18775 VNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSA-TLAWLPPLRDGGAKIDGY 18833
Query: 1207 RITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKESVPISD 1261
IT+ Q + E S L G +Y V V +E+ + +
Sbjct: 18834 -ITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYE 18892
Query: 1262 TIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK---NEEDV---AELS 1315
+PP + P+ + + I+ + + K E++V + L+
Sbjct: 18893 AKEQLLPPKI------LMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLA 18946
Query: 1316 ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP----TGIDFSDITA 1371
+ +D++ +L + S E T + + +D+P D SDI A
Sbjct: 18947 VHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDA 19006
Query: 1372 NSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH----SRNSITLTNLTPGTEYVVS 1427
++ ++ W P G I ++ R D V ++ S + L PG EY+
Sbjct: 19007 DACSLSWHIPLED-GGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFR 19065
Query: 1428 IVALN--GREE---SPLLIGQ-QSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRIT 1481
+ A N G E SP ++ Q V P++ V + ++WD P
Sbjct: 19066 VRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRP---------- 19115
Query: 1482 YGETGGNSPVQEFTVPGSKSTATI----------------SGLKPGVDYTITVYAVTGRG 1525
++ G SP+ + + + + + +GL G++Y+ +YA+ G
Sbjct: 19116 --DSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAG 19173
Query: 1526 DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPKNG 1581
SP S + R +D P + +V DV +++S+ W S + GY V G
Sbjct: 19174 SSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPG 19233
Query: 1582 PGPTKTKTAGPD--QTEMTIEGLQPTVEYVVSVYAQN------PSGESQP---LVQTAVT 1630
+ TA Q E T GL+ +Y A+ PS S P L +
Sbjct: 19234 DKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPP 19293
Query: 1631 NIDRPKGL-------AFTDVDVDSIKIAWESPQGQVS-RYRVTYSSPEDGIHELFPAPDG 1682
ID + A T+V +D+ + P VS + T P +GI A
Sbjct: 19294 RIDLSVAMKSLLTVKAGTNVCLDA--TVFGKPMPTVSWKKDGTLLKPAEGIK---MAMQR 19348
Query: 1683 EEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQ 1741
T EL + ++ A + I + P P +K ++
Sbjct: 19349 NLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLS 19408
Query: 1742 WTPP----NVQLTGYRVRVTPKEKTGP-MKEINLAPDSSSVVVSGLMVATKYEVSV---- 1792
W PP ++T Y V +E + P +++ +S V L+ +Y+ +
Sbjct: 19409 WEPPLEDGGSEITNY--IVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAEN 19466
Query: 1793 -YALKDTLTSRPAQGVVTTLENVSPPRRAR---VTDATETTITISWRTKTE----TITGF 1844
Y + D + + PA PP R +++ T+ +T+SW+ + ITG+
Sbjct: 19467 KYGVGDPVFTEPA----IAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGY 19522
Query: 1845 QVDAVPANGQTPIQRTIKPDV-RSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI 1903
++ + KP + R+ TGLQ GT+Y+ + +N P DAS A
Sbjct: 19523 LLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKP--SDASKAA 19580
Query: 1904 DA---------PSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPR 1950
A P+ + TT +S+ +SW P + I GY+++ ++ S
Sbjct: 19581 YARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNL 19640
Query: 1951 PRP-GVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
P+ T +TGL T+Y V A+ S+P
Sbjct: 19641 PQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDP 19675
Score = 123 bits (309), Expect = 2e-27
Identities = 282/1358 (20%), Positives = 482/1358 (35%), Gaps = 200/1358 (14%)
Query: 780 LLPGRKYIVNVYQISEDGE----QSLILSTSQTTAPDAPPD-PTVDQVDDTSIVVRWSRP 834
L+ G +YI V ++ G+ QS + P PP+ P V V + V W RP
Sbjct: 20536 LIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRP 20595
Query: 835 Q----APITGYRIVYSPSVEGSSTE-LNLPETANSVTLSDLQPGVQYNITIYA-----VE 884
+ ITGY + + P + ++ LQ G Y + A +
Sbjct: 20596 VDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 20655
Query: 885 ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVD 940
E++ V+ ++ P + P D T ++ W P +TGY V+
Sbjct: 20656 PPSEASDSVLMKDAAYPPGPPSNPHVTD-----TTKKSASLAWGKPHYDGGLEITGYVVE 20710
Query: 941 VIPVN----LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ--QT 994
V + G L I++ V L Y F++ A++ +P +
Sbjct: 20711 HQKVGDEAWIKDTTGTALRITQFV---VPDLQTKEKYNFRISAINDAGVGEPAVIPDVEI 20767
Query: 995 TKLDAPTNLQFVNETDSTVLVR-------WTP----PRAQITGYRLTVGLTRRGQPRQYN 1043
+ + + + E T++VR + P P ++T + + L R
Sbjct: 20768 VEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTE 20827
Query: 1044 VGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI 1103
++ P N ++ +++ G + V T P ++ P T++T+ ++
Sbjct: 20828 -SFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRP--TDITKDSV 20884
Query: 1104 VITWT-PAPRIGFKLGVRPSQGGEAPREVTSDSGS------IVVSGLTPGVEYVYTIQVL 1156
+ W P G ++ + EA R+ S + + V+GL+ G EY + +
Sbjct: 20885 TLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAE 20944
Query: 1157 RD---GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITT 1210
+ G+ + K SPP +L++ + ++++W + ITGY I
Sbjct: 20945 NEYGIGEPTETTEPVKASEAPSPPDSLNI-MDITKSTVSLAWPKPKHDGGSKITGYVIEA 21003
Query: 1211 TPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTII----PA 1266
Q + V + C NL+ G EY V V S P +
Sbjct: 21004 QRKGSDQWTHITTVKGLE---CVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQT 21060
Query: 1267 VPPPTDLR-------FTNIGPDT---MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316
+ P DLR G + + V P P++ K + + + +
Sbjct: 21061 MLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTW----------KKGDQILKQTQ 21110
Query: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL-------------DSPTG 1363
+ + +L E V S S Y PL R G PTG
Sbjct: 21111 RVNFETTATSTILNINECVRSDSGPY------PLTARNIVGEVGDVITIQVHDIPGPPTG 21164
Query: 1364 -IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNL 1418
I F +++++ T W P I+ Y + S E R + T L
Sbjct: 21165 PIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTD-STTWVELATTVIRTTYKATRL 21223
Query: 1419 TPGTEYVVSIVALN------GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP- 1471
T G EY + A N G + ++ V P +V A T S+ ISW P
Sbjct: 21224 TTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPL 21283
Query: 1472 ---AVTVRYYRITYGETGGN--SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD 1526
+ Y + E G V + VPG+ + SGL G+ Y V A G
Sbjct: 21284 SDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKS--SGLTDGIAYEFRVIAENMAGK 21341
Query: 1527 SPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGP 1582
S S + ID P + ++ +++++KW +T Y V
Sbjct: 21342 SKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNG 21401
Query: 1583 GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ--TAVTNIDRPKGLAF 1640
K + + E T+ GL Y V A+N +G P + A+T D
Sbjct: 21402 RWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRD------- 21454
Query: 1641 TDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGL-------- 1692
DV+ IK+ + + + + D P + +D EL+G
Sbjct: 21455 -DVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIA 21513
Query: 1693 -------------RPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTD--LKFTQVTPTS 1737
R YT++ A + ++ + + P P + L T+VT
Sbjct: 21514 DFSTNLVNKDSTRRDSGAYTLT--ATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEK 21571
Query: 1738 LSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKY--- 1788
W PP ++ Y + K +T + N+A + + + V+ L+ +Y
Sbjct: 21572 CVLSWFPPLDDGGAKIDHY---IVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFR 21628
Query: 1789 --EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISW----RTKTETIT 1842
V+ Y + + L S P V PP+ VT T+ ++ + W I
Sbjct: 21629 VMAVNKYGVGEPLESEPVL-AVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEII 21687
Query: 1843 GFQVDAVPANGQTPIQRTIK--PDVRSYTITGLQPGTDYKIYLYTLNDNARSSP------ 1894
+ V+ GQ I+ K D+R Y ++GL G +Y+ + N S+P
Sbjct: 21688 NYIVERRDKAGQRWIKCNKKTLTDLR-YKVSGLTEGHEYEFRIMAENAAGISAPSPTSPF 21746
Query: 1895 -VVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVP 1949
D P N R L T+ +S+ ++W P + ITGY+++ P ++V
Sbjct: 21747 YKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVT 21806
Query: 1950 RPRP-GVTEATITGLEPGTEYTIYVIALKNNQKSEPLI 1986
P T TITGL EY I + A+ + EP +
Sbjct: 21807 PPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPAL 21844
Score = 121 bits (303), Expect = 9e-27
Identities = 287/1414 (20%), Positives = 508/1414 (35%), Gaps = 177/1414 (12%)
Query: 610 GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
GP E + T + WN P ++IS YI+ R + + W + + +Y
Sbjct: 24803 GPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLS-WTQVSTEVQALNY 24861
Query: 667 TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
+ L PG Y +++++ +YG E P+ S VT P ++
Sbjct: 24862 KVTKLLPGNEYIFRVMAVNKYGIGE-------------PLESGPVTACNPYKPPGPPSTP 24908
Query: 727 SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEP-----QYLDLPSTATSVNIPDLL 781
V+ IT S VV+W D G +E + E+ D+ + T + + L
Sbjct: 24909 EVSAITKDSMVVTWARPVDD-GGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLT 24967
Query: 782 PGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPP-DPTVDQVDDTSIVVRWSRP- 834
G Y N + E E S+ P PP +P V +S+ + WS+P
Sbjct: 24968 EGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPI 25027
Query: 835 ---QAPITGYRIVYSPSVEGSSTELNLPE--TANSVTLSDLQPGVQYNITIYAVEENQES 889
AP+ GY + + T P T++ L+ +YN I A+
Sbjct: 25028 YDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVG 25087
Query: 890 TPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK--------VTIMWTP-PE---SAVTGY 937
P + R + D +V ++ VTI P PE G
Sbjct: 25088 EPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGI 25147
Query: 938 RVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL 997
D + + + VT G Y + G ++ + +
Sbjct: 25148 LTDRAQIEVTSS------FTMLVIDNVTRFDSG--RYNLTLENNSGSKTAFVNVRVLDSP 25199
Query: 998 DAPTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPL 1053
AP NL +V + W PP A+IT Y + T R + + + +
Sbjct: 25200 SAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRI 25259
Query: 1054 RNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN------TEVTETTIVITW 1107
NLQ Y ++A + E TT S PP +VT T I W
Sbjct: 25260 ENLQEGCSYYFRVLA---SNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKW 25316
Query: 1108 T-PAPRIGFKLG----VRPSQGGEAPREVTS-DSGSIVVSGLTPGVEYVYTIQVLR---- 1157
P G K+ ++G E T + +SGLT G EYV+ + +
Sbjct: 25317 EKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGR 25376
Query: 1158 -DGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGY-RITTTPTNG 1215
D ++ P++ + + + P L V D+ R T
Sbjct: 25377 SDPRQLGVPVIARDIE-IKPSVELPFHT------FNVKAREQLKIDVPFKGRPQATVNWR 25429
Query: 1216 QQGNSLEEVVHADQSSC---TFDNLSPGLEYNVSVYTVKDDKES----VPISDTIIPAVP 1268
+ G +L+E + SS T ++ + +V Y + + VPI+ ++
Sbjct: 25430 KDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPG 25489
Query: 1269 PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAE---LSISPSDNA 1322
PP +R + D++ ++W PP ++N++V K E +S + + +
Sbjct: 25490 PPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVE----KKETTSTTWHIVSQAVARTS 25545
Query: 1323 VVLTNLLPGTEYVVSVSS-----VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTV 1376
+ + L G+EY V + ES+ + P G T ++ V
Sbjct: 25546 IKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLV 25605
Query: 1377 HWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN 1432
W P + + GY + + + +++ + + ++ L G Y + A N
Sbjct: 25606 TWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAEN 25665
Query: 1433 ----GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGE 1484
G+ D P EV T S+ + W P + Y + E
Sbjct: 25666 IAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRE 25725
Query: 1485 TGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEID 1543
++ ++ ++ L Y V+A S S I + +++
Sbjct: 25726 LPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVE 25785
Query: 1544 KPSQMQVTDVQDNSI--SVKWLPSSSPVTG--YRVTTTPKNG---PGPTKTKTAGPD-QT 1595
P M +D + + + L ++ + G V + K+G +T+ D T
Sbjct: 25786 PPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHT 25845
Query: 1596 EMTIEGL--QPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKG--LAFTDVDVDSIKIA 1651
+T++ + T +YV+++ +N +G V V + P L + + ++
Sbjct: 25846 LLTVKDCIRRDTGQYVLTL--KNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLS 25903
Query: 1652 WESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGE--EDTAELQGLRPGSEYTVSVVAL 1705
W PQ + Y V + H + +GE + ++ L G+EY V +
Sbjct: 25904 WGRPQEDGGADIDYYIV---EKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGV 25960
Query: 1706 HDDMESQPLIGTQSTAIPA---------PTDLKFTQVTPTSLSAQWTPP----NVQLTGY 1752
+ +PL +S AI A PT L+ T VT S++ W+ P +++GY
Sbjct: 25961 NKYGVGEPL---ESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGY 26017
Query: 1753 RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTT 1810
+ K ++ V +GL +YE VYA S P++ ++
Sbjct: 26018 IIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRA 26077
Query: 1811 LENV---SPPRRARVTDATETTITISWRTKT----ETITGFQVD---AVPANGQTPIQRT 1860
+ V SPP + ++ D+ +TTITI+W ITG+ V+ + + +T IQ
Sbjct: 26078 EDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSL 26137
Query: 1861 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP 1894
+ YTI+GL G +Y + ++N S P
Sbjct: 26138 RGTE---YTISGLTTGAEYVFRVKSVNKVGASDP 26168
Score = 120 bits (302), Expect = 1e-26
Identities = 326/1553 (20%), Positives = 547/1553 (35%), Gaps = 248/1553 (15%)
Query: 605 YPSSSGPVEVFITETPSQPNSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEA-TIP 660
Y P+ V IT+ S + W P+ + I+ Y++ R K S+ RW A T+
Sbjct: 13188 YDVPGPPLNVTITDVNRFGVS--LTWEPPEYDGGAEITNYVIELRDKTSI-RWDTAMTVR 13244
Query: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
S T+ V EGQ S + R S +TP E P P
Sbjct: 13245 AEDLSATVTD-----VVEGQEYSFRVRAQN---RIGVGKPSAATPFVKVADPIER-PSPP 13295
Query: 721 LVATSESVTEITASSFVVSWV----SASDTVSGFRVEYELSEEGDEPQY---LDLPSTAT 773
+ TS T+ SS + W + G+ +E EEG + + L T
Sbjct: 13296 VNLTSSDQTQ---SSVQLKWEPPLKDGGSPILGYIIER--CEEGKDNWIRCNMKLVPELT 13350
Query: 774 SVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV---DDTSIVVR 830
+ L G KY+ V ++ G TA DA +PT+D D ++V
Sbjct: 13351 -YKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIV- 13408
Query: 831 WSRP---QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSD-----LQPGVQYNITIYA 882
P P TGY + G L + TLS + P + + IY
Sbjct: 13409 -PNPITILVPSTGYPRPTATWCFGDKV-LETGDRVKMKTLSAYAELVISPSERSDKGIYT 13466
Query: 883 VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYR 938
++ + + + R +P++L+F ++T V + W PP+ S +TGY
Sbjct: 13467 LKLENRVKTISGEIDVNVIARPS---APKELKFGDITKDSVHLTWEPPDDDGGSPLTGYV 13523
Query: 939 VDVIPVNLPGEHGQRLPISRNTFAE-----------VTGLSPGVTYYFKVFAVSHGRESK 987
V ++ +SR T+ + V L G Y FKV A + +
Sbjct: 13524 V------------EKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGE 13571
Query: 988 PLTAQQTTKL-------DAPTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRR 1036
P + + D P N+++ + T +++ + W PP+ ++I GY V R
Sbjct: 13572 PAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGY--IVERCPR 13629
Query: 1037 GQPRQYNVGPSV--SKYPLRNLQPASEYTVSLVAIK-----------------GNQESPK 1077
G + G V +K + L+ Y + A+ QE+P+
Sbjct: 13630 GSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPE 13689
Query: 1078 ATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGF-KLGVRPSQGGEAPREVTSDSG 1136
+F ++ + + E +T P P+I + K + Q E
Sbjct: 13690 ---IFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKS 13746
Query: 1137 SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHL-EANPDTGVLTVSW 1195
++ + Y I+ + A + V+ PP + + ++ +LT +
Sbjct: 13747 TVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNP 13806
Query: 1196 ERST-TPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV-----YT 1249
R IT Y + T+ + + L V T L P EY V Y
Sbjct: 13807 PRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKAT--KLIPNKEYIFRVAAENMYG 13864
Query: 1250 VKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPV 1305
V + ++ PI+ P PPT L ++I D + +TW P +T + V
Sbjct: 13865 VGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDP 13924
Query: 1306 KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGID 1365
++ V + D + L +Y V + P + + + P
Sbjct: 13925 DTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPP 13984
Query: 1366 F-------SDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPR-EDRVPHSRNSI 1413
+ D+ S ++W P A I Y I R + VP +++
Sbjct: 13985 WPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH-- 14042
Query: 1414 TLTNLTPGTEYVVSIVALNGREES-------PLLIGQQSTVSDVPRDLEVVAATPTSLLI 1466
L L G EY + A+N ES P+L ++ PR LEV+ T + +
Sbjct: 14043 LLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADL 14102
Query: 1467 SWDAPAVTVRYYRITYGETGGNSPVQEFTVPG---------------SKSTATISGLKPG 1511
W P E G SP+ + V + T++ L G
Sbjct: 14103 KWTVP------------EKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEG 14150
Query: 1512 VDYTITVYAVTGRGDSPASSKPISINYR---TEIDKPSQMQVTDVQDNSISVKWLPSSS- 1567
Y V A G S + S+ + T P + V DV + +KW P +
Sbjct: 14151 SLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKND 14210
Query: 1568 ---PVTGYRVTTTPKNGPGPTKT-KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
P+ Y + + G K KTAGPD + ++ T E V A+N +G P
Sbjct: 14211 GGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGT-EVQFQVRAENEAGVGHP 14269
Query: 1624 LVQTAVTNIDRPKG-------LAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHEL 1676
T + +I+ P L TD I IAW+ P+ SP G H +
Sbjct: 14270 SEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPE-------KNGGSPIIGYH-V 14321
Query: 1677 FPAPDGEEDTAEL-------------QGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP 1723
P G E + +G+ P EY + V A++ S+P +++
Sbjct: 14322 EMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAK 14381
Query: 1724 APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLM 1783
P D K T T + + G ++ + + P+ ++ D V S +
Sbjct: 14382 DP-DCKPTIDLETH-------DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRL 14433
Query: 1784 VATKYEVSVYALKDTLTSRPAQGVVT-TLEN----------------VSPPRRARVTDAT 1826
+S + L+ + R G+ T TLEN P + + +D T
Sbjct: 14434 TMKNDHISAH-LEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDIT 14492
Query: 1827 ETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIY 1882
+++ ++W I + ++ A +T I + S+T+ L P +Y
Sbjct: 14493 KSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFR 14552
Query: 1883 LYTLND-------NARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARIT 1931
+ +N ++ + D D P ++ T ++ ++W+PP ++I
Sbjct: 14553 VKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIM 14612
Query: 1932 GYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
GYII+ G + + T GLE G EY V A SEP
Sbjct: 14613 GYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEP 14665
Score = 118 bits (296), Expect = 6e-26
Identities = 316/1543 (20%), Positives = 554/1543 (35%), Gaps = 238/1543 (15%)
Query: 607 SSSGPVEVFIT----ETPSQPNSHPIQWNAPQPSHISKYILRWRP---------KNSVGR 653
+SSG F+T +TP P + ++ + L W P KN V
Sbjct: 24099 NSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSA-----FLVWEPPIIDGGAKVKNYVID 24153
Query: 654 WKEATIPGHLN--------SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTP 705
+E+T + N S+ ++ L G +Y ++++ ++G P
Sbjct: 24154 KRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG-------------VGVP 24200
Query: 706 VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGD 761
V + P SP ++T+++ +S + W V G+ VE + +G
Sbjct: 24201 VETVDAVKAAEPPSP--PGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE--MQPKGT 24256
Query: 762 EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQ 821
E + S + + L G++Y V +E G+ + A D P++
Sbjct: 24257 EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKL 24316
Query: 822 VDDTSIVVRWS--RPQAPITGY-RIVYSPSVEGS----STELNLPETANSVTLSDLQPGV 874
+T + + + P+ G R S +G +T +N+ ETA S L ++ G
Sbjct: 24317 PFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLH-IKEGN 24375
Query: 875 QYNITIYAVEENQESTPV-----VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTP 929
+ + Y V + VI E G P ++F EV+ V I W P
Sbjct: 24376 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGP-------VRFDEVSADFVVISWEP 24428
Query: 930 PESA----VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE 985
P ++ Y V+ H ++R T ++T L G Y F++FA + +
Sbjct: 24429 PAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTI-KITKLKTGTEYQFRIFAENRYGK 24487
Query: 986 SKPLTA-----QQTTKLDAPTNLQFVNE-TDSTVLVRWTPP----RAQITGYRLTVGLTR 1035
S PL + Q K P FV + +LV+W P +I GY L
Sbjct: 24488 SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 24547
Query: 1036 RGQPRQYNVGP-SVSKYPLRNLQPASEYT--VSLVAIKGNQESPKATGVFTTLQPGSSIP 1092
+ N P +K+ L EY VS I G + K + F P P
Sbjct: 24548 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCD--P 24605
Query: 1093 PYNTE---VTETTIVITWT-PAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
P E +T + + W PA G K+ + + P G + + T +E
Sbjct: 24606 PGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLP------DGRWMKASFTNVLE 24659
Query: 1149 YVYTIQVLRDGQERDAPIVNK-VVTPLSPPT---------------NLHLEANPDTGVLT 1192
+T+ L + Q + ++ + S P+ N L+ ++
Sbjct: 24660 TEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVV 24719
Query: 1193 VSWERSTTP-DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLS---------PGLE 1242
+ E DI G I + + G LEE + T + G +
Sbjct: 24720 HAGETFVLEADIRGKPIPDVVWS-KDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 24778
Query: 1243 YNVSVYTVKDDKESVPISDTIIPAVPPPTD-LRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301
Y + + V K S+PI+ ++ PP L+ T + + + W PP N
Sbjct: 24779 YILKLSNVGGTK-SIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHY 24837
Query: 1302 YSPVKNEEDVAELSISPSDNAV--VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1359
+ ++ +S A+ +T LLPG EY+ V +V + PL T +
Sbjct: 24838 IIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACN 24897
Query: 1360 S------PTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHS 1409
P+ + S IT +S V W P I GY + + + ++ +
Sbjct: 24898 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 24957
Query: 1410 RNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTV---SDVPRDLEVVAATPT 1462
+ +T LT G Y + A N G P + + P + +V + +
Sbjct: 24958 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRS 25017
Query: 1463 SLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-----------------TI 1505
S+ ++W P G +PV+ + V ++ A T+
Sbjct: 25018 SVSLAWSKPIYD------------GGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTV 25065
Query: 1506 SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPS 1565
+ LK +Y + A+ G ++ P S+ + I+ P D++ V L +
Sbjct: 25066 TKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLR----KVVVLRA 25121
Query: 1566 SSPVTGYRVTTTPKNGPGPT----KTKTAGPD--QTEMTIEGLQPTVEYVV-------SV 1612
S+ + R+ T K P P K + D Q E+T ++ V ++
Sbjct: 25122 SATL---RLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNL 25178
Query: 1613 YAQNPSGESQPLVQTAVTNI-DRPKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYS 1667
+N SG V V + P L +V DS+ ++WE P +++ Y V
Sbjct: 25179 TLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKR 25238
Query: 1668 SPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT- 1726
+ + + T ++ L+ G Y V+A ++ P T+ + P
Sbjct: 25239 ETTRKAYATI-TNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPL 25297
Query: 1727 ---DLKFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPK--EKTGPMKEINLAPDSSSV 1777
+ VT + + +W P ++TGY V + K EK ++ +
Sbjct: 25298 PPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVK----TLEA 25353
Query: 1778 VVSGLMVATKYEVSVYALKDTLTSRPAQ-GVVTTLENVS-------PPRRARVTDATETT 1829
+SGL +Y V A+ + S P Q GV ++ P V +
Sbjct: 25354 TISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLK 25413
Query: 1830 ITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ----PGTDYKIYLYT 1885
I + ++ + + ++ D GQT + T S T+T L D Y
Sbjct: 25414 IDVPFKGRPQATVNWRKD-----GQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELC 25468
Query: 1886 LNDNARSS--PVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEK 1939
++++A S P+ I P +R + +S+ +SW PP +I+ YI++ ++
Sbjct: 25469 VSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKE 25528
Query: 1940 PGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 1982
S +V + T I L G+EY V A KS
Sbjct: 25529 TTSTTWHIVSQ-AVARTSIKIVRLTTGSEYQFRVCAENRYGKS 25570
Score = 118 bits (295), Expect = 8e-26
Identities = 287/1359 (21%), Positives = 491/1359 (36%), Gaps = 205/1359 (15%)
Query: 780 LLPGRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP 834
++ G +YI VN Y I E E +++ + P P P V ++ S+ V WSRP
Sbjct: 27030 IIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRP 27089
Query: 835 QA----PITGYRIVYSPSVEGSSTEL---NLPETANSVTLSDLQPGVQYNI-TIYAVEEN 886
A I+GY + ++ + +T VT QY + + A +
Sbjct: 27090 IADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQG 27149
Query: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVI 942
S P + D P ++ + T +T+ W+ P SAVTGY V++
Sbjct: 27150 PFSEP---SEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEI- 27205
Query: 943 PVNLPGEHGQRLPIS-----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK- 996
GE + +S R T V+ L PGV YYF+V AV+ + +P+ + +
Sbjct: 27206 ---RQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQA 27262
Query: 997 ---LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--------RQYNVG 1045
L+AP E D V +R T A+ G + V + +G+P + N+G
Sbjct: 27263 KDILEAP-------EIDLDVALR-TSVIAK-AGEDVQVLIPFKGRPPPTVTWRKDEKNLG 27313
Query: 1046 PSVSKYPLRNLQPASEYTVS----------LVAIKGNQESPKATGVFTTL--QPGSSIPP 1093
S ++Y + N +S T+ ++ I+ PK++ V + P +
Sbjct: 27314 -SDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKL 27372
Query: 1094 YNTEVTETTIVITWTP------APRIGFKLGVRPS---QGGEAPREVTSDSGSIV-VSGL 1143
V+ T+ + W P +P I + + R + + +S S ++ +S
Sbjct: 27373 QVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEK 27432
Query: 1144 TPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDI 1203
TP V + G+ + K +P +L ++ + T V+ +SW T PD
Sbjct: 27433 TPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVI-LSW---TKPDF 27488
Query: 1204 TGYRITTTPTNGQQGNSLEEVVHADQS-SCTFD----NLSPGLEYNVSVYTVKDDKESVP 1258
G + T ++G + HA S +C + LE+ V K + V
Sbjct: 27489 DGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVT 27548
Query: 1259 ISDTIIP--AVPPPTDLRFTNIGPDTMRV----------TWAPPPSIDLTNFLVRYSPVK 1306
I + + P DL T+R+ P PSI ++L P+K
Sbjct: 27549 IGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSI---SWLKDGLPLK 27605
Query: 1307 NEEDVAELSISPSDNAVVLT----NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1362
E V S ++N + L+ G +Y V + + + P+ P
Sbjct: 27606 ESEFV---RFSKTENKITLSIKNAKKEHGGKYTVILDNAV-CRIAVPITVITLGPPSKPK 27661
Query: 1363 G-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
G I F +I A+S + W P IT Y I E + +R + + N
Sbjct: 27662 GPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKR-ETSQTNWKMVCSSVARTTFKVPN 27720
Query: 1418 LTPGTEYVVSIVALNGREESPLLIG------QQSTVSDVPRDLEVVAATPTSLLISWDAP 1471
L EY + A N S L+ Q + P + T + ++WDAP
Sbjct: 27721 LVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAP 27780
Query: 1472 AV----TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
V + + E + T P S +GL G+DY VYA G S
Sbjct: 27781 VYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLS 27840
Query: 1528 PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPG 1583
S + +D P DV +I++KW P S + GY + N
Sbjct: 27841 SPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERW 27900
Query: 1584 PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN------PSGESQPLVQTAVTNIDRPKG 1637
+ + + T+ GL P Y + A+N P +S ++ T N+ P
Sbjct: 27901 -VRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENV--PPI 27957
Query: 1638 LAFTDVDVDSI--------------------KIAWESPQGQVSRYRVTYSSPEDGIHELF 1677
+ F D + ++ W ++ + + G LF
Sbjct: 27958 VEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLF 28017
Query: 1678 PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTS 1737
+ T + +G+ YTV +++ + Q T ++FT +T
Sbjct: 28018 V----RDATRDHRGV-----YTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEK 28068
Query: 1738 LSAQWTPP-NVQLTGYRVRVTPKEKTGPM--KEINLAPDSSSVVVSGLMVATKYEVSVYA 1794
++ W P N + K +T + I ++ S L+ +Y+ V A
Sbjct: 28069 MTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSA 28128
Query: 1795 LKDTLTSRP--AQGVVTTLENVSP--PRRARVTDATETTITISWRTKTETITGFQVDA-- 1848
+ RP + VV ++ P P ++ T +IT++W + E+ G ++
Sbjct: 28129 VNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTW-ARPESDGGSEIQQYI 28187
Query: 1849 -----------VPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1897
V + PI T + +TGL G +Y+ ++ + +NA
Sbjct: 28188 LERREKKSTRWVKVISKRPISET------RFKVTGLTEGNEYEFHV--MAENAAGVGPAS 28239
Query: 1898 DASTAIDA---------PSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPP 1944
S I P+ ++ T+ ++ + W P I GYII+ K
Sbjct: 28240 GISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGD 28299
Query: 1945 REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 1983
V T T+T L+ G EY V A+ K +
Sbjct: 28300 WHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGD 28338
Score = 117 bits (293), Expect = 1e-25
Identities = 324/1541 (21%), Positives = 541/1541 (35%), Gaps = 222/1541 (14%)
Query: 612 VEVFITETPSQPNSHPIQ----------WNAPQP---SHISKYILRWRPKNSVGRWKEAT 658
VEV + + P P + I WN P+ S I+ Y++ R +S W + +
Sbjct: 13776 VEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEV-WHKLS 13834
Query: 659 IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
++ L P Y ++ + YG E PV ++ +T +
Sbjct: 13835 STVKDTNFKATKLIPNKEYIFRVAAENMYGVGE-------------PVQASPITAKYQFD 13881
Query: 719 SPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATS 774
P T ++IT + ++W D ++G+ VE + + +P T+
Sbjct: 13882 PPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTT 13941
Query: 775 VNIPDLLPGRKYIVNVY--QISEDGEQSL----ILSTSQTTAPDAPPDPTVDQVDDTSIV 828
+ L +KY V ++ G+ S IL P P PTV V TS+
Sbjct: 13942 YRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVR 14001
Query: 829 VRWSRPQ----APITGY--RIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA 882
+ W++P+ A I Y ++ + + E +P T + L L G +Y+ + A
Sbjct: 14002 LNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH--LLPGLMEGQEYSFRVRA 14059
Query: 883 VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYR 938
V + ES P + PR L+ + +T + WT PE S +T Y
Sbjct: 14060 VNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYI 14119
Query: 939 VDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH-GR------ESKPLTA 991
V+ V G + ++T VT L+ G Y F+V A + G+ E L
Sbjct: 14120 VEKRDVRRKGWQTVDTTV-KDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAK 14178
Query: 992 QQTTKLDAPTNLQFVNETDSTVLVRWTPPR--AQITGYRLTVGLTRRGQPRQYNVGPSVS 1049
T P L V+ T V ++W PP+ R + R R G +
Sbjct: 14179 DTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAG 14238
Query: 1050 KYPLRNLQPASEYTVSLVAIKGNQES-----PKATGVFTTLQPGS-SIPPYNTEVTET-- 1101
+ E T ++ E+ + T + + P S PP + VT+
Sbjct: 14239 PDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGR 14298
Query: 1102 -TIVITWTP------APRIGFKLGVRPSQGGEAPREVTS----DSGSIVVSGLTPGVEYV 1150
I I W P +P IG+ + + P G E V S D V G+ P EYV
Sbjct: 14299 KHIAIAWKPPEKNGGSPIIGYHVEMCP-VGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYV 14357
Query: 1151 YTIQVLRD-GQERDAPIVNKVVT--PLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYR 1207
++ + G + I VV P PT + LE + ++ + E+ + P +R
Sbjct: 14358 LRVRAVNAIGVSEPSEISENVVAKDPDCKPT-IDLETH---DIIVIEGEKLSIP--VPFR 14411
Query: 1208 ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY------NVSVYTV----KDDKESV 1257
PT + +EV +D+ + D++S LE + +YT+ K +
Sbjct: 14412 AVPVPTVSWHKDG-KEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATA 14470
Query: 1258 PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSIS 1317
I+ +I P D++ ++I + ++TW PP T L + + +
Sbjct: 14471 SINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVM 14530
Query: 1318 PSDNAVVLT--NLLPGTEYVVSVSSV-------YEQHESTPLRGRQKTGLDSPTGIDFSD 1368
+N + T +L+P EY V +V Y + ++ + K D P ++ +
Sbjct: 14531 SGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHN 14590
Query: 1369 ITANSFTVHWIAP----RATITGYRIRH--HPEHFSGRPREDRVPHSRNSITLTNLTPGT 1422
TA + T+ W P + I GY I E R E VP + T L G
Sbjct: 14591 PTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPIL--TYTAKGLEEGK 14648
Query: 1423 EYVVSIVALNGREESPLLIGQQSTVSDVPRDL-EVVAATPTSLL----ISWDAPAVTVRY 1477
EY + A N S T + P D +V+ T + I+ DA Y
Sbjct: 14649 EYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPY 14708
Query: 1478 YRITY------------------------GETGGNSP-----VQEFTVPGSKSTATISGL 1508
IT+ GE P Q ++ SK + +
Sbjct: 14709 PTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRV 14768
Query: 1509 KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP---- 1564
+ + +Y + D + P +++ P D++ S+ KW P
Sbjct: 14769 RDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDD 14828
Query: 1565 SSSPVTGYRVTTTPKNGP-GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
S + Y + K P T+ + ++ L EY+ V A+N G P
Sbjct: 14829 GGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPP 14888
Query: 1624 LVQTAVT------NIDRPKGLAFTDVDVDSIKIAWESPQ-------GQVSRYRVTYSSPE 1670
V + D P DV +S+ + W P+ G R S+
Sbjct: 14889 CVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHW 14948
Query: 1671 DGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD------DMESQPLIGTQSTAIPA 1724
+++ A + GL G Y V A + S P + P
Sbjct: 14949 SRVNKSLL----NALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPG 15004
Query: 1725 PTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV--- 1777
P + T + T++ +W PP ++ GY V K+ G + V
Sbjct: 15005 PPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFV---DKQLVGTNEWSRCTEKMIKVRQY 15061
Query: 1778 VVSGLMVATKYEVSVYALKDTLTSRPAQ-GVVTTLENVSPPRRARVTDATETTITISWRT 1836
V + Y++ V A+ P + VT E PP A E +++
Sbjct: 15062 TVKEIREGADYKLRVSAVNAAGEGPPGETQPVTVAEPQEPP-------AVELDVSVKGGI 15114
Query: 1837 KTETITGFQVDAVPANGQTPIQRTIKPD--------------VRSYTITGLQPGTDYKIY 1882
+ ++ AV P + K + +S I D+ Y
Sbjct: 15115 QIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRY 15174
Query: 1883 LYTLNDNARSSPVVIDASTAIDAPS---NLRFLATTPNSLLVSWQPPR----ARITGYII 1935
+ T N+ S D P +L+ + T L++W P + ITG+II
Sbjct: 15175 VITAT-NSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFII 15233
Query: 1936 KYEKPGSPP-REVVPRPRPGVTEATITGLEPGTEYTIYVIA 1975
+ + R+ + R ++ ITGL G EY VIA
Sbjct: 15234 ERKDAKMHTWRQPIETER---SKCDITGLLEGQEYKFRVIA 15271
Score = 117 bits (293), Expect = 1e-25
Identities = 292/1326 (22%), Positives = 488/1326 (36%), Gaps = 202/1326 (15%)
Query: 811 PDAPPDPT-VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSV 865
P P P + V + + W P+ + IT Y I + + ++ +
Sbjct: 16217 PGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTY 16276
Query: 866 TLSDLQPGVQYNITIYAVEENQESTPVVIQQETT-------GTPRSDTVPSPRDLQFVEV 918
T+ L G +Y I A + P+ + ET G P TV S V
Sbjct: 16277 TIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSS--------V 16328
Query: 919 TDVKVTIMWTPPE----SAVTGYRVDVIPVNLPG-EHGQRLPISRNTFA---EVTGLSPG 970
T +T+ W PE S VTGY +++ + R PI T +VTGL G
Sbjct: 16329 TRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEG 16388
Query: 971 VTYYFKVFAVSHGR------ESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR--- 1021
Y F+V+A++ S P TA+ P + + T S+ + W+PP
Sbjct: 16389 SDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDG 16448
Query: 1022 -AQITGYRLTVGLTRRGQPRQYNVGPSV----SKYPLRNLQPASEYT--VSLVAIKGNQE 1074
+++TGY V G+ ++ G +K + L+ + Y V V I G E
Sbjct: 16449 GSKVTGY--IVEYKEEGK-EEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGE 16505
Query: 1075 SPKATGVFTT--------LQPGSSIPP----YNTEVTETTIVITWTPAPRIGFKLGVRPS 1122
+ T V LQ +S+ + V ++ P P + + + R +
Sbjct: 16506 PGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNER-T 16564
Query: 1123 QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT---PLSPPTN 1179
EA E T+ S S+V+ + VY++ + ER I+ V+ P+ P
Sbjct: 16565 LPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFL 16624
Query: 1180 LHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239
H N + S E IT Y I ++ + + V + + T L
Sbjct: 16625 AHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTV--TRQNATVQGLIQ 16682
Query: 1240 GLEY--------NVSVYTVKDDKESVPISDTIIPAVPP-PTDLRFTNIGPDTMRVTWAPP 1290
G Y ++ + + E++ I + I VP P DL + +T+ +TW PP
Sbjct: 16683 GKAYFFRIAAENSIGMGPFVETSEALVIREPI--TVPERPEDLEVKEVTKNTVTLTWNPP 16740
Query: 1291 P---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHES 1347
++ N+++ + E+ + + + L G Y VS+V +
Sbjct: 16741 KYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQG 16800
Query: 1348 TPLRGRQ----KTGLDSPT-GIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPR 1402
P + K L PT +DF D T+ + +TG +SG+P+
Sbjct: 16801 KPSFCTKPITCKDELAPPTLHLDFRD----KLTIR-VGEAFALTG--------RYSGKPK 16847
Query: 1403 ------EDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQST--------VS 1448
+D + T TP T + I A ++ + ST V+
Sbjct: 16848 PKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVN 16907
Query: 1449 DVPRDLEVVA------ATPTSLLISWDAP----AVTVRYYRITYGETGGN--SPVQEFTV 1496
V R V T ++ISW P + Y I E G + PV T
Sbjct: 16908 VVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPV---TS 16964
Query: 1497 PGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEI-DKPSQMQVTDVQ 1554
+K+T +S L G DY ++A G S P S + R + D P Q VT+V
Sbjct: 16965 ASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVT 17024
Query: 1555 DNSISVKWLP---SSSPVTGY---RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEY 1608
+S V W P+T Y + T K TK T+ + L +Y
Sbjct: 17025 KDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIH--PYTKFRVPDLLEGCQY 17082
Query: 1609 VVSVYAQN------PSGESQPL-VQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQ----G 1657
V A+N PS S+P+ + + P D +S+ + W+ P+
Sbjct: 17083 EFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGS 17142
Query: 1658 QVSRYRVTYSSPEDGI-HELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLI 1715
++ Y V Y D P+ +T ++ GLR G Y V+A++ ES P
Sbjct: 17143 KILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDP-- 17200
Query: 1716 GTQSTAIPAPTDLKFTQVTP-TSLSAQWTPPNVQLTGYRVRVT------PKEKTGPMKEI 1768
+P P +K P L A G +R++ P K KE
Sbjct: 17201 ----AHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKED 17256
Query: 1769 NLAPDSSSVVVSGLMVATKYEV--------SVYAL--KDTLTSRPAQGVVTTLENVSPPR 1818
AP + + V+ V +K E+ +Y+L ++ S+ V L+ PPR
Sbjct: 17257 RDAPTKARIDVT--PVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPR 17314
Query: 1819 RARVTDATETTITISWRTKTE----TITGFQVDA--VPANGQTPIQRTIKPDVRSYTITG 1872
V++ + + ++W+ + IT + V+ V + +P+ T K +S+
Sbjct: 17315 DLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKK--KSHFAKH 17372
Query: 1873 LQPGTDYKIYLYTLNDNARSSPV-------VIDASTAIDAPSNLRFLATTPNSLLVSWQP 1925
L G Y + N R V +D P +L + + + W
Sbjct: 17373 LNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNK 17432
Query: 1926 P----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 1981
P + ITGY+++Y++ G+ ++ + E +TGL+ G Y V K
Sbjct: 17433 PDRDGGSPITGYLVEYQEEGT--QDWIKFKTVTNLECVVTGLQQGKTYRFRV-------K 17483
Query: 1982 SEPLIG 1987
+E ++G
Sbjct: 17484 AENIVG 17489
Score = 112 bits (281), Expect = 3e-24
Identities = 265/1361 (19%), Positives = 500/1361 (36%), Gaps = 176/1361 (12%)
Query: 766 LDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT 825
+D + TS I + G K + ++ G+ ++ P + V + D
Sbjct: 13045 IDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDG 13104
Query: 826 SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPG-VQYNIT 879
+ + W P + I GY +V ++ + L + T++ LQ G V+Y
Sbjct: 13105 EVSLAWEEPLTDGGSKIIGY-VVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFR 13163
Query: 880 IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVT 935
+ A PV + D P ++ +V V++ W PPE + +T
Sbjct: 13164 VSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEIT 13223
Query: 936 GYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT 995
Y +++ + + A VT + G Y F+V A + KP A
Sbjct: 13224 NYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFV 13283
Query: 996 KL-------DAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR---- 1040
K+ P NL ++T S+V ++W PP + I GY + G+
Sbjct: 13284 KVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGY--IIERCEEGKDNWIRC 13341
Query: 1041 QYNVGPSVSKYPLRNLQPASE--YTVSLVAIKGNQESPKATGVFTT----LQPGSSIPPY 1094
+ P ++ Y + L+ ++ Y VS G + + G T ++P + +
Sbjct: 13342 NMKLVPELT-YKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAF 13400
Query: 1095 NTEV-----TETTIVI--TWTPAPRIGFKLGVRPSQGGEAPREVT-SDSGSIVVSGLTPG 1146
+ TI++ T P P + G + + G+ + T S +V+S
Sbjct: 13401 KDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERS 13460
Query: 1147 VEYVYTIQVLRDGQERDAPI-VNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD--- 1202
+ +YT+++ + I VN + P +P + D+ LT WE PD
Sbjct: 13461 DKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLT--WE---PPDDDG 13515
Query: 1203 ---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY--NVSVYTVKDDKESV 1257
+TGY + + + + + V T +L G EY V E
Sbjct: 13516 GSPLTGYVVEKREVSRKTWTKVMDFV--TDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 13573
Query: 1258 PISDTIIPAVP-----PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEE 1309
+ + + + P PP ++++ + +++ +TW PP + + ++V P +++
Sbjct: 13574 YVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDK 13633
Query: 1310 DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDI 1369
VA ++ + +T L G Y V ++ Q S P R ++ +D +
Sbjct: 13634 WVA-CGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEI-----QAVDTQEA 13687
Query: 1370 TANSFTVHWIAPRATITGYRIRHHPEHFSGRP-------REDRVPHSRNSITLTNLTPGT 1422
V +A G +I P +G+P + D + IT+ N+
Sbjct: 13688 PEIFLDVKLLAGLTVKAGTKI-ELPATVTGKPEPKITWTKADMILKQDKRITIENVP--K 13744
Query: 1423 EYVVSIVALNGREESPLLI------GQQSTVSDV--------PRDLEVVAATPTSLLISW 1468
+ V+IV + +I G+ + V +V P ++ T S L++W
Sbjct: 13745 KSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTW 13804
Query: 1469 DAP----AVTVRYYRITYGETGG------NSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
+ P + Y + T +S V++ +K L P +Y V
Sbjct: 13805 NPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATK-------LIPNKEYIFRV 13857
Query: 1519 YAVTGRG-DSPASSKPISINYRTE-IDKPSQMQVTDVQDNSISVKWL----PSSSPVTGY 1572
A G P + PI+ Y+ + P++++ +D+ +++++ W SP+TGY
Sbjct: 13858 AAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGY 13917
Query: 1573 RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LV 1625
V + + T ++GL +Y V A+N +G +P L+
Sbjct: 13918 WVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILI 13977
Query: 1626 QTAVTNIDRPKGLAFTDVDVDSIKIAWESPQ--GQVSRYRVTYSSPEDGIHELFPAPDGE 1683
+ + P DV S+++ W P+ G + G E +G
Sbjct: 13978 KDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGV 14037
Query: 1684 EDTAE-LQGLRPGSEYTVSVVALHDDMESQ------PLIGTQSTAIPAPTD-LKFTQVTP 1735
T L GL G EY+ V A++ ES+ P++ + P+P L+ +T
Sbjct: 14038 PTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITK 14097
Query: 1736 TSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS 1791
+ +WT P +T Y V + G + ++ + V+ L E S
Sbjct: 14098 NTADLKWTVPEKDGGSPITNYIVEKRDVRRKG-WQTVDTTVKDTKCTVTPLT-----EGS 14151
Query: 1792 VYALKDTLTSRPAQGVVTTLEN----------VSPPRRARVTDATETTITISWRTKT--- 1838
+Y + + Q T +E+ PP V D T+ + + W
Sbjct: 14152 LYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDG 14211
Query: 1839 -ETITGFQVDAVPANGQTPIQ--RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP- 1894
I + ++ G ++ +T PD ++ +T + GT+ + + N+ P
Sbjct: 14212 GRPIQRYVIEKKERLGTRWVKAGKTAGPDC-NFRVTDVIEGTEVQFQVRAENEAGVGHPS 14270
Query: 1895 ------VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPP 1944
+ D ++ P +L + ++W+PP + I GY ++ G+
Sbjct: 14271 EPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEK 14330
Query: 1945 -REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
V RP + G+ P EY + V A+ SEP
Sbjct: 14331 WMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEP 14371
Score = 107 bits (266), Expect = 2e-22
Identities = 292/1356 (21%), Positives = 513/1356 (37%), Gaps = 189/1356 (13%)
Query: 727 SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQ--YLDLPSTA--TSVNIPDLLP 782
+VTE+T+ V+SW D G ++++ + ++ + + + ++ S T + + LL
Sbjct: 21563 AVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 21621
Query: 783 GRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAP 837
G +YI VN Y + E E +L+ + PD P +P V + S+VV W P +
Sbjct: 21622 GNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDS- 21680
Query: 838 ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ-------PGVQYNITIYAVEENQEST 890
G + + VE N TL+DL+ G +Y I A S
Sbjct: 21681 -DGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISA 21739
Query: 891 PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNL 946
P P + + ++ + ++I W P S +TGY V++ L
Sbjct: 21740 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIA---L 21796
Query: 947 PGEHGQRLPIS----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD---A 999
P E ++ + T +TGL+ Y +++A++ +P T K +
Sbjct: 21797 PEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRML 21856
Query: 1000 PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR---QYNVGPSVSKYPLRNL 1056
P ++ + V +R RL V + R P + G S+ K ++
Sbjct: 21857 PPEIELDADLRKVVTIR------ACCTLRLFVPIKGRPAPEVKWARDHGESLDK---ASI 21907
Query: 1057 QPASEYTVSLVAIKGNQESPK----------ATGVFTTLQ----PGSSIPPYNTEVTETT 1102
+ S YT+ +V +S K + F ++ PG EVT+T+
Sbjct: 21908 ESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTS 21967
Query: 1103 IVITWTPAPRI--GFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQ 1154
+ +TW P P + G K+ + E+ R+ S S V L G Y + +
Sbjct: 21968 VTLTWDP-PLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYF--R 22024
Query: 1155 VLRDGQ------ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITG 1205
VL + + A V PL P ++ ++ +++SWE+ I G
Sbjct: 22025 VLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNS--VSLSWEKPEHDGGSRILG 22082
Query: 1206 YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKE-SVPI 1259
Y I T G + V +++ T L G EY+ V + D ++ SVP+
Sbjct: 22083 Y-IVEMQTKGSDKWATCATVKVTEATIT--GLIQGEEYSFRVSAQNEKGISDPRQLSVPV 22139
Query: 1260 --SDTIIPAVPPPTDLRFTNIGPDTMRV----TWAPPPSIDLTNFLVRYSPVKNEEDVAE 1313
D +IP FT + + ++V P P++ V P+K
Sbjct: 22140 IAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNV---PLK---QTTR 22193
Query: 1314 LSISPSDNAVVLTNLLPGTE----YVVSV-SSVYEQHESTPLRGRQKTGLDSPTG-IDFS 1367
++ ++N +LT E YVV + +S E E+ + K G PTG +
Sbjct: 22194 VNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG--PPTGPVKMD 22251
Query: 1368 DITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423
++TA+S T+ W P+ ++I Y + + + + +R +I L G E
Sbjct: 22252 EVTADSITLSWGPPKYDGGSSINNYIVEKR-DTSTTTWQIVSATVARTTIKACRLKTGCE 22310
Query: 1424 YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPT-------SLLISWDAP----A 1472
Y I A N +S L + TV+ P + TP S+ + W+ P
Sbjct: 22311 YQFRIAAENRYGKSTYL-NSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGG 22369
Query: 1473 VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSK 1532
V Y + E V+ P ++ +GL+ GV+Y V A G S
Sbjct: 22370 SRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKV 22429
Query: 1533 PISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTK 1588
R D P + + V NS++++W S +TGY V K
Sbjct: 22430 SECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKAS 22489
Query: 1589 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-SQPLVQT-AVTNIDR--PKGLAFTDVD 1644
T + GL Y V A+N +G S+P T A+T D P ++
Sbjct: 22490 FTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKY 22549
Query: 1645 VDSIKI-AWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVV 1703
D+I + A ES + Y P I + G+++ + L S + +
Sbjct: 22550 KDTIVVHAGESFKVDAD----IYGKPIPTIQWI----KGDQELSNTARLEIKSTDFATSL 22601
Query: 1704 ALHDD---------MESQPLIGTQSTAI-------PAPTD--LKFTQVTPTSLSAQWTPP 1745
++ D ++++ + G +S + P P + + + VT + W PP
Sbjct: 22602 SVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPP 22661
Query: 1746 NVQLTGYRV--RVTPKEKTGPM--KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1801
+Q G + + + +T + ++ + S V+ L+ +Y + A+
Sbjct: 22662 -LQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVG 22720
Query: 1802 RPAQGVVTTLEN--VSP--PRRARVTDATETTITISWRTKT----ETITGFQVDAVPANG 1853
P + +N V P P+ VT T+ ++ + W I G+ ++ G
Sbjct: 22721 EPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEG 22780
Query: 1854 --QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDA-STAID------ 1904
T + + ++R +TGL DY+ + N S P A A D
Sbjct: 22781 IRWTRCHKRLIGELR-LRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPG 22839
Query: 1905 APSNLRFLATTPNSLLVSWQPP----RARITGYIIK 1936
P+N + + T +S+ +SW P I GYI++
Sbjct: 22840 PPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVE 22875
Score = 106 bits (265), Expect = 2e-22
Identities = 338/1705 (19%), Positives = 582/1705 (34%), Gaps = 213/1705 (12%)
Query: 606 PSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGH 662
P GPVE+ + + W P S I YIL R + + W +
Sbjct: 20473 PGPPGPVEI----SNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRL-LWTVVSEDIQ 20527
Query: 663 LNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLV 722
+ L G Y ++ ++ YG E PV S V P
Sbjct: 20528 SCRHVATKLIQGNEYIFRVSAVNHYGKGE-------------PVQSEPVKMVDRFGPPGP 20574
Query: 723 ATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778
V+ +T ++ VSW D ++G+ VE + + + P + +
Sbjct: 20575 PEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVT 20634
Query: 779 DLLPGRKYIVNVYQISEDG------EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS 832
L G Y V + G +L P P +P V S + W
Sbjct: 20635 GLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWG 20694
Query: 833 RPQ----APITGYRIVYSPSVEGSSTELNLPETANSVT---LSDLQPGVQYNITIYAVEE 885
+P ITGY +V V + + TA +T + DLQ +YN I A+ +
Sbjct: 20695 KPHYDGGLEITGY-VVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAIND 20753
Query: 886 NQESTPVVIQQ-ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPV 944
P VI E + +L+ V ++I P V
Sbjct: 20754 AGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKD 20813
Query: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYF--KVFAVSHGRESKPLTAQQTTKLDAP-- 1000
N+ ++ + NT + + P Y K K LD P
Sbjct: 20814 NINLKNRANI---ENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGP 20870
Query: 1001 -TNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSK-----YPLR 1054
NL+ + T +V + W P G R+T + + + + + + +K Y +
Sbjct: 20871 VLNLRPTDITKDSVTLHWDLPLID-GGSRITNYIVEKREATRKSYSTATTKCHKCTYKVT 20929
Query: 1055 NLQPASEYTVSLVAIK--GNQESPKATGVFTTLQPGSSIPPYNT-EVTETTIVITWTPAP 1111
L EY ++A G E + T + S N ++T++T+ + W P P
Sbjct: 20930 GLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAW-PKP 20988
Query: 1112 R-------IGFKLGVRPSQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVL----RDG 1159
+ G+ + + +G + +T+ G VV LT G EY + + + R
Sbjct: 20989 KHDGGSKITGYVIEAQ-RKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSA 21047
Query: 1160 QERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE--RSTTPDITGYRITTTPTNGQQ 1217
P++ K T L L L V+ + + + P + + T T G Q
Sbjct: 21048 PRESRPVIVKEQTMLP---ELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQ 21104
Query: 1218 G-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAV-----PPPT 1271
+ V ++ T N++ + + Y + + D I V PP
Sbjct: 21105 ILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTG 21164
Query: 1272 DLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNL 1328
++F + D + +W PP + + ++N++V + V EL+ + T L
Sbjct: 21165 PIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWV-ELATTVIRTTYKATRL 21223
Query: 1329 LPGTEYVVSVSS-----VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAP- 1381
G EY V + V S + + P G + +T +S T+ W P
Sbjct: 21224 TTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPL 21283
Query: 1382 ---RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------ 1432
+ I GY + + + N + LT G Y ++A N
Sbjct: 21284 SDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSK 21343
Query: 1433 -GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1491
+ P+L P L + T T + W P T + +Y + P
Sbjct: 21344 PSKPSEPMLALDPIDPPGKPVPLNITRHTVT---LKWAKPEYTGGFKITSYIVEKRDLPN 21400
Query: 1492 QEFTVPG----SKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPS 1546
+ ++ T+SGL Y V A G SP S +I R +++ P
Sbjct: 21401 GRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPK 21460
Query: 1547 QMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTK------TKTAGPDQTEMTIE 1600
+D I +R+ P PT + G + E+ I
Sbjct: 21461 IKVDVKFKDTVI-------LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIA 21513
Query: 1601 GLQPTV---------EYVVSVYAQNPSGESQPLVQTAVTNIDRP----KGLAFTDVDVDS 1647
+ ++ A NP G ++ + V +DRP LA T+V +
Sbjct: 21514 DFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKV--LDRPGPPEGPLAVTEVTSEK 21571
Query: 1648 IKIAWESP---QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVA 1704
++W P G + + + A + + ++ L G+EY V+A
Sbjct: 21572 CVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMA 21631
Query: 1705 LH-----DDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPPN----VQLTGYRV 1754
++ + +ES+P++ P P + + T +T S+ W P+ ++ Y V
Sbjct: 21632 VNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIV 21691
Query: 1755 RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYA-----LKDTLTSRPAQGVVT 1809
K +K VSGL +YE + A + + P
Sbjct: 21692 ERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACD 21751
Query: 1810 TLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVD-AVPANGQTPIQRTIKP- 1863
T+ PP RV D + ++I+I+W ITG+ V+ A+P + I + P
Sbjct: 21752 TVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQI---VTPP 21808
Query: 1864 ---DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAS---------TAIDAPSNLRF 1911
SYTITGL +YKI +Y +N P ++ + I+ ++LR
Sbjct: 21809 AGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRK 21868
Query: 1912 LATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTI 1971
+ T + P +K+ + + I G +
Sbjct: 21869 VVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLIVGNVNRFDSGK 21928
Query: 1972 YVIALKNNQKSEPLIGRKKTDELP--------QLVTLPHPNL-HGPEILDVPSTVQKTPF 2022
Y++ ++N+ S+ + + P + VT L P +LD S ++ +
Sbjct: 21929 YILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKN--Y 21986
Query: 2023 VTHPGYDTGNGIQLPGTSGQQPS--VGQQM--------IFEEHGFRRTTPPTTATPIRHR 2072
+ T T+ + S V Q + E+ + P TA ++
Sbjct: 21987 IVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKAS 22046
Query: 2073 PRPYPPNVGQEALSQTT-----ISW-APFQDTSE----YIISCHPVGTDEEPLQFRVPGT 2122
RP PP G+ L T +SW P D YI+ G+D+ V
Sbjct: 22047 ERPLPP--GKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATV--K 22102
Query: 2123 STSATLTGLTRGATYNIIVEALKDQ 2147
T AT+TGL +G Y+ V A ++
Sbjct: 22103 VTEATITGLIQGEEYSFRVSAQNEK 22127
Score = 106 bits (264), Expect = 3e-22
Identities = 321/1571 (20%), Positives = 563/1571 (35%), Gaps = 259/1571 (16%)
Query: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWR 646
YG G+ +P++ P V + + N+ I+W P+ S I+ Y++ +
Sbjct: 25278 YGIGLPAETTEPVKVSEPPLPPGRVTLVDVTR--NTATIKWEKPESDGGSKITGYVVEMQ 25335
Query: 647 PKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPV 706
K S +W T L + TI GL G Y ++ ++ + G + + PV
Sbjct: 25336 TKGSE-KWSTCTQVKTLEA-TISGLTAGEEYVFRVAAVNEKGRSDPRQL-------GVPV 25386
Query: 707 TSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL 766
+ + E P L + +V V + +R + + +E +
Sbjct: 25387 IARDI--EIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVN-V 25443
Query: 767 DLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDP---TVDQVD 823
T TS++I + K V Y++ I D P P +D+V
Sbjct: 25444 SSSKTVTSLSIKE---ASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVS 25500
Query: 824 DTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNIT 879
SI + W+ P+ I+ Y + + + ++ S+ + L G +Y
Sbjct: 25501 CDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFR 25560
Query: 880 I-----YAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE--- 931
+ Y ES+ VV + P S P P + V T + + W P
Sbjct: 25561 VCAENRYGKSSYSESSAVVAEY-----PFSPPGP-PGTPKVVHATKSTMLVTWQVPVNDG 25614
Query: 932 -SAVTGYRVDVIP-VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA---VSHGRES 986
S V GY ++ ++ ++ I+ +T +V+GL G+ Y ++V+A G+ S
Sbjct: 25615 GSRVIGYHLEYKERSSILWSKANKILIA-DTQMKVSGLDEGLMYEYRVYAENIAGIGKCS 25673
Query: 987 K---PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR----AQITGY-----RLTVG-- 1032
K P+ A+ D P + N T +V ++W+ P A+ITGY L G
Sbjct: 25674 KSCEPVPARDPC--DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRW 25731
Query: 1033 --------------LTRRGQPRQY-------NVGPSVSKYPLRNLQPASEYTVSLVAIKG 1071
+T + ++Y N SVS+ SE T ++ +K
Sbjct: 25732 LKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSE--------PSESTGPII-VKD 25782
Query: 1072 NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGF-KLGVRPSQGGEAPRE 1130
+ E P+ V ++ I EV + I P P I + K G+ +
Sbjct: 25783 DVEPPR---VMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEII 25839
Query: 1131 VTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGV 1190
T + + V Y + + R + KV+ PP LE N T
Sbjct: 25840 STDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAG-PLEINGLTAE 25898
Query: 1191 -LTVSWERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY--- 1243
++SW R DI Y + T+ E + +SC L G EY
Sbjct: 25899 KCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQ--MTSCKVTKLLKGNEYIFR 25956
Query: 1244 --NVSVYTVKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTN 1297
V+ Y V + ESV I VP PPT L T++ ++M + W+ P S +++
Sbjct: 25957 VTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISG 26016
Query: 1298 FLVRYSPVKNEEDVAELSISP-SDNAVVLTNLLPGTEYVVSV-----SSVYEQHESTPL- 1350
+++ KN ++ P D V T L G EY V + + E++PL
Sbjct: 26017 YIIERRE-KNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLI 26075
Query: 1351 RGRQKTGLDS-PTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDR 1405
R L S P+ D + T+ W+ P A ITGY + + + +
Sbjct: 26076 RAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEY--KKSDDTDWKTS 26133
Query: 1406 VPHSRNS-ITLTNLTPGTEYVVSIVALN-----------------GREESPLLIGQQSTV 1447
+ R + T++ LT G EYV + ++N REE PL
Sbjct: 26134 IQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLF----DID 26189
Query: 1448 SDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT-VPGSKSTATI- 1505
S++ + L V A ++ + + V + + + + + + S+++ TI
Sbjct: 26190 SEMRKTLIVKAGASFTMTVPFRGRPVP----NVLWSKPDTDLRTRAYVDTTDSRTSLTIE 26245
Query: 1506 -SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW-L 1563
+ YT+T+ V A+S + + P+ + V DV S + W +
Sbjct: 26246 NANRNDSGKYTLTIQNVLS-----AASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDV 26300
Query: 1564 PSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
P + +PV Y + + T ++ + LQ Y V +N G
Sbjct: 26301 PENDGGAPVKNYHIEKREASKKAWVSV-TNNCNRLSYKVTNLQEGAIYYFRVSGENEFGV 26359
Query: 1621 SQPLVQTAVTNIDR----PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTY--SSPEDGIH 1674
P I P+ L T + DS+ + W P+ V Y + E G
Sbjct: 26360 GIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQK 26419
Query: 1675 ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVT 1734
+ + GLR SEY V A E+Q + P +L +
Sbjct: 26420 NWVKCAVAKSTHHVVSGLRENSEYFFRVFA-----ENQ-------AGLSDPREL----LL 26463
Query: 1735 PTSLSAQWTPPNVQL-----------TGYRVRVTPKEKTGPMKEINLAPD---------- 1773
P + Q PP + + G ++V P+ ++ L+ D
Sbjct: 26464 PVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRF 26523
Query: 1774 SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV------VTTLENVSPPR-RARVTDAT 1826
++ + L + K V+ A + +T+ + G + L+ PP ++D T
Sbjct: 26524 NTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDIT 26583
Query: 1827 ETTITISWR---------------TKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTIT 1871
E ++T+ W K ET T AV + RT+ +
Sbjct: 26584 EESVTLKWEPPKYDGGSQVTNYILLKRETST-----AVWTEVSATVARTM------MKVM 26632
Query: 1872 GLQPGTDYKIYL-----YTLNDNARSSPVVIDASTAIDAPSNLRFLA-TTPNSLLVSWQP 1925
L G +Y+ + + ++D+ S+ V + P + ++ T S+ V W
Sbjct: 26633 KLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHE 26692
Query: 1926 P----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL----- 1976
P + + GY ++ + S + + T +T + G Y V A
Sbjct: 26693 PVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGV 26752
Query: 1977 -KNNQKSEPLI 1986
K + SEP++
Sbjct: 26753 GKPSHPSEPVL 26763
Score = 106 bits (264), Expect = 3e-22
Identities = 279/1348 (20%), Positives = 495/1348 (36%), Gaps = 168/1348 (12%)
Query: 773 TSVNIPDLLPGRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSI 827
TS + LL G +YI VN Y + E E I + T P P + V S+
Sbjct: 25940 TSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESM 25999
Query: 828 VVRWSRPQAP----ITGYRIVYSPSVEGSSTELNL-PETANSVTLSDLQPGVQYNITIYA 882
+ WSRP++ I+GY I +N P V + L+ G +Y +YA
Sbjct: 26000 TLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYA 26059
Query: 883 VEENQESTPVVIQQETTGTPRSDT---VPSPRDL-QFVEVTDVKVTIMWTPP----ESAV 934
+ + + + ET+ R++ +PSP + V+ +TI W P + +
Sbjct: 26060 ----ENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPI 26115
Query: 935 TGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA--- 991
TGY V+ + + + R T ++GL+ G Y F+V +V+ S P +
Sbjct: 26116 TGYTVEYKKSD-DTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDP 26174
Query: 992 QQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP------------ 1039
Q + + +E T++V+ G T+ + RG+P
Sbjct: 26175 QIAKEREEEPLFDIDSEMRKTLIVK--------AGASFTMTVPFRGRPVPNVLWSKPDTD 26226
Query: 1040 ---RQYNVGPSVSKYPLR----NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIP 1092
R Y V + S+ L N + +YT+++ + V T P ++I
Sbjct: 26227 LRTRAY-VDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNIT 26285
Query: 1093 PYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDSG--SIVVSGLT 1144
+VT+ + V++W AP + + R + +A VT++ S V+ L
Sbjct: 26286 VQ--DVTKESAVLSWDVPENDGGAPVKNYHIEKREASK-KAWVSVTNNCNRLSYKVTNLQ 26342
Query: 1145 PGVEYVYTIQVLRD---GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW---ERS 1198
G Y + + + G + K+ SPP L + + V +++W E
Sbjct: 26343 EGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSV-SLTWLKPEHD 26401
Query: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
I Y + Q N ++ V A + L EY V+ S P
Sbjct: 26402 GGSRIVHYVVEALEKG--QKNWVKCAV-AKSTHHVVSGLRENSEYFFRVFAENQAGLSDP 26458
Query: 1259 ISDTIIPAV------PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVA 1312
+ ++P + PP D++ N T+ V +D+ V D
Sbjct: 26459 -RELLLPVLIKEQLEPPEIDMK--NFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGV 26515
Query: 1313 ELSISPSDNA-VVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD--------SPTG 1363
L + N + NL + V+ + + + G K ++ PTG
Sbjct: 26516 PLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTG 26575
Query: 1364 -IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNL 1418
+ SDIT S T+ W P+ + +T Y + E + E +R + + L
Sbjct: 26576 PVVISDITEESVTLKWEPPKYDGGSQVTNYILLKR-ETSTAVWTEVSATVARTMMKVMKL 26634
Query: 1419 TPGTEYVVSIVALNGR------EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA 1472
T G EY I A N + + + + T P V T S+ + W P
Sbjct: 26635 TTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPV 26694
Query: 1473 VT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSP 1528
V Y + + + + + ++ + G+ Y VYA G
Sbjct: 26695 SNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGK 26754
Query: 1529 ASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGP 1584
S + + P +++TD+ NS+S+ W S +TGY V
Sbjct: 26755 PSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRW 26814
Query: 1585 TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-SQPL-VQTAVTNIDRPKGLAFTD 1642
TK +T+ I GL +Y V+A+N G S P V +T ID G D
Sbjct: 26815 TKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVI-D 26873
Query: 1643 VDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSV 1702
+ ++ ++ + G + R S E + D E T L + ++ +
Sbjct: 26874 LPLEYTEVV-KYRAGTSVKLRAGISGKPAPTIEWYK-DDKELQTNALVCVENTTDLASIL 26931
Query: 1703 VALHDDMES-------QPLIGTQSTAI---------PAPTDLKFTQVTPTSLSAQWTPP- 1745
+ D + S + +G+ S I P ++F VT ++ W PP
Sbjct: 26932 IKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPA 26991
Query: 1746 ---NVQLTGYRVRVTPKEKTGPM--KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT 1800
++T Y + K +T + ++ + + + ++ +Y V A+
Sbjct: 26992 DDGGAKITHY---IVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGI 27048
Query: 1801 SRPAQGVVTTLENV----SPPRRARVTDATETTITISWRTKT----ETITGFQV---DAV 1849
P + +N PP VT T+ ++T+ W I+G+ + D
Sbjct: 27049 GEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKK 27108
Query: 1850 PANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNAR---SSPVVI-DASTAIDA 1905
++ TI+ D R +TGL +DY+ + +N + S P A+ ID
Sbjct: 27109 SLGWFKVLKETIR-DTRQ-KVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDP 27166
Query: 1906 P---SNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVP-RPRPGVTE 1957
P + +R +T +S+ + W P + +TGY+++ + V + TE
Sbjct: 27167 PGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTE 27226
Query: 1958 ATITGLEPGTEYTIYVIALKNNQKSEPL 1985
++ L+PG Y V A+ + EP+
Sbjct: 27227 YVVSNLKPGVNYYFRVSAVNCAGQGEPI 27254
Score = 103 bits (256), Expect = 3e-21
Identities = 283/1422 (19%), Positives = 486/1422 (34%), Gaps = 190/1422 (13%)
Query: 730 EITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRK 785
+IT S ++W D ++G+ VE + +D T +PDL+ G++
Sbjct: 13498 DITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFV-TDLEFTVPDLVQGKE 13556
Query: 786 YIVNVYQISE--DGEQSLILSTSQTTAPDAPPDP--TVDQVDDT--SIVVRWSRPQ---- 835
Y+ V ++ GE + + + P PDP V D T SI + W P+
Sbjct: 13557 YLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGG 13616
Query: 836 APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ 895
+ I GY + P P + ++ L+ G Y + A+ S P
Sbjct: 13617 SRIKGYIVERCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPT 13676
Query: 896 QETTGTPRSDTVPSPRDLQFVEVTDVKV-------TIMWTPPESAVTGYRVDVIPVNLPG 948
+E + D++ + VK + PE +T + D+I
Sbjct: 13677 EEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKR 13736
Query: 949 EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE 1008
+ +P + S TY + V GR + + K P +
Sbjct: 13737 ITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVC-GRATAVVEVNVLDKPGPPAAFDITDV 13795
Query: 1009 TDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTV 1064
T+ + L+ W PPR ++IT Y + T + + + + L P EY
Sbjct: 13796 TNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIF 13855
Query: 1065 SLVA--IKGNQESPKATGVFTTLQPGSSIPPYNTE---VTETTIVITWTP------APRI 1113
+ A + G E +A+ + Q PP E +T+ + +TW +P
Sbjct: 13856 RVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPIT 13915
Query: 1114 GF---KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTI---QVLRDGQERDAPIV 1167
G+ +L + + D+ + V GLT +Y + + + G+ +
Sbjct: 13916 GYWVERLDPDTDKWVRCNKMPVKDT-TYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEP 13974
Query: 1168 NKVVTPLSPPTNLHLEANPDTGVLTV--SWERSTTPDITGYRITTTPTNGQQGNSLEEVV 1225
+ P+ PP D G +V +W T P+ G + +E V
Sbjct: 13975 ILIKDPIDPPWPPGKPTVKDVGKTSVRLNW---TKPEHDGGAKIESYVIEMLKTGTDEWV 14031
Query: 1226 HADQSSCTFDNLSPGL----EYNVSVYTVKDDKESVPI--SDTIIPAVP-----PPTDLR 1274
+ T +L PGL EY+ V V ES P SD ++ PP L
Sbjct: 14032 RVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLE 14091
Query: 1275 FTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
NI +T + W P +TN++V V+ + + + D +T L G
Sbjct: 14092 VINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRK-GWQTVDTTVKDTKCTVTPLTEG 14150
Query: 1332 TEYVVSVS-------SVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR-- 1382
+ YV V+ S Y + E + L T P + D+T + W P+
Sbjct: 14151 SLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKND 14210
Query: 1383 --ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREE 1436
I Y I + + + + +T++ GTE + A N G
Sbjct: 14211 GGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPS 14270
Query: 1437 SP---LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQE 1493
P L I ++ P DL V A + I+W P E G SP+
Sbjct: 14271 EPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPP------------EKNGGSPIIG 14318
Query: 1494 FTVP----GSKSTATIS-------------GLKPGVDYTITVYAVTGRGDSPASSKPISI 1536
+ V G++ ++ G+ P +Y + V AV G S+P I
Sbjct: 14319 YHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIG----VSEPSEI 14374
Query: 1537 NYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1596
+ P D++ + I V S +R P + D+
Sbjct: 14375 SENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLT 14434
Query: 1597 MTIEGLQPTVEYVVSVYA---------QNPSGESQPLVQTAVTNIDRP-KGLAFTDVDVD 1646
M + + +E SV A +N G + + V + P K + +D+
Sbjct: 14435 MKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKS 14494
Query: 1647 SIKIAWESPQ--GQVSRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVSVV 1703
S K+ WE P+ G E G P GE + ++ L P EY V
Sbjct: 14495 SCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVK 14554
Query: 1704 ALH-----DDME-SQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPP----NVQLTGY 1752
A++ + +E P+I P P D++ T +++ W PP ++ GY
Sbjct: 14555 AVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGY 14614
Query: 1753 RV-RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTL 1811
+ ++ E+ +L P + GL +Y+ V A S P++ T
Sbjct: 14615 IIEKIAKGEERWKRCNEHLVP-ILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPT- 14672
Query: 1812 ENVSPPRRARVTDATETTI------------------TISWRTKTETITGFQVD------ 1847
+ V P +V T + TI+W I ++
Sbjct: 14673 KAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPL 14732
Query: 1848 --------------AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL-NDNA-R 1891
+P + I + K + + L+P D+ +Y+ + ND+
Sbjct: 14733 VRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRP--DHGLYMIKVENDHGIA 14790
Query: 1892 SSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPRE- 1946
+P + P N F S+L W+PP + I Y ++ + P E
Sbjct: 14791 KAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEW 14850
Query: 1947 VVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGR 1988
+V + ++T L G EY V A P + +
Sbjct: 14851 IVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSK 14892
Score = 101 bits (252), Expect = 8e-21
Identities = 253/1300 (19%), Positives = 457/1300 (35%), Gaps = 239/1300 (18%)
Query: 718 FSPLVATSESVTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTA- 772
F P T+ + + T +S ++W + G+ VE + + +E + P T
Sbjct: 23918 FKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVE--ICKADEEEWQIVTPQTGL 23975
Query: 773 --TSVNIPDLLPGRKYIVNVYQISEDG--EQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828
T I L ++Y + V +++ G E + + T + P+ +D IV
Sbjct: 23976 RVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIV 24035
Query: 829 VRW---SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYN-ITIYAVE 884
VR +R P G +P + S E + ++ GV Y ++I +
Sbjct: 24036 VRAGGSARIHIPFKGRP---TPEITWSREEGEFTDKVQ------IEKGVNYTQLSIDNCD 24086
Query: 885 ENQESTPVVIQQETTGTPRS-------DTVPSPRDLQFVEVTDVKVTIMWTPP----ESA 933
N ++ + ++G+ + DT P++L EV ++W PP +
Sbjct: 24087 RNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAK 24146
Query: 934 VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ 993
V Y +D S+ +F +V L+ G YYF+V A + P+
Sbjct: 24147 VKNYVIDKRESTRKAYANVSSKCSKTSF-KVENLTEGAIYYFRVMAENEFGVGVPVETVD 24205
Query: 994 TTKLDAP------TNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYN 1043
K P L V++T ++++ W P +++ GY V + +G +
Sbjct: 24206 AVKAAEPPSPPGKVTLTDVSQTSASLM--WEKPEHDGGSRVLGY--VVEMQPKGTEKWSI 24261
Query: 1044 VGPS-VSKYPLRNLQPASEYTVSLVAIKGNQES-PKATGV-----FTTLQPGSSIPPYNT 1096
V S V + L EY + A +S P+ GV T+QP + P+NT
Sbjct: 24262 VAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKL-PFNT 24320
Query: 1097 EVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVL 1156
+ G + E+ V+ P + +V
Sbjct: 24321 YSIQA----------------------GEDLKIEIP------VIGRPRPNISWV------ 24346
Query: 1157 RDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQ 1216
+DG+ PL T +++E + VL + + D Y +T T + G
Sbjct: 24347 KDGE------------PLKQTTRVNVEETATSTVLHI--KEGNKDDFGKYTVTATNSAGT 24392
Query: 1217 QGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFT 1276
+L +V PG PP +RF
Sbjct: 24393 ATENLSVIVLE----------KPG---------------------------PPVGPVRFD 24415
Query: 1277 NIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLP 1330
+ D + ++W PP ++N++V K + +S + + + +T L
Sbjct: 24416 EVSADFVVISWEPPAYTGGCQISNYIVE----KRDTTTTTWHMVSATVARTTIKITKLKT 24471
Query: 1331 GTEYVVSVSSVYEQHESTPLRGR-----QKTGLDSPTGIDF-SDITANSFTVHWIAP--- 1381
GTEY + + +S PL + P G F + I+ + V W P
Sbjct: 24472 GTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVND 24531
Query: 1382 -RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440
I GY + ++ + ++ P T L G EY + A E+ +
Sbjct: 24532 GGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSA-----ENIVG 24586
Query: 1441 IGQQSTVS---------DVPRDLEVVAATPTSLLISWDAPAV----TVRYYRITYGETGG 1487
IG+ S VS D P E + T ++ + W PA + Y + +
Sbjct: 24587 IGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPD 24646
Query: 1488 NSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPS 1546
++ ++ T+SGL Y V A G+ S S +I R EID P+
Sbjct: 24647 GRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPN 24706
Query: 1547 QMQVTDVQDNSI--SVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
+D + + + + + G + + G +TA + + TI+
Sbjct: 24707 ASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTL 24766
Query: 1605 TV---------EYVVSVYAQNPSG-ESQPLVQTAVTNIDRPKG-LAFTDVDVDSIKIAWE 1653
V +Y++ + N G +S P+ + P+G L T V + +AW
Sbjct: 24767 VVKDCIRTDGGQYILKL--SNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWN 24824
Query: 1654 SP----QGQVSRY--------RVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVS 1701
P +S Y R++++ + L ++ L PG+EY
Sbjct: 24825 PPLQDGGANISHYIIEKRETSRLSWTQVSTEVQAL---------NYKVTKLLPGNEYIFR 24875
Query: 1702 VVALH-----DDMESQPLIGTQSTAIPAPTDL-KFTQVTPTSLSAQWTPP----NVQLTG 1751
V+A++ + +ES P+ P P + + +T S+ W P ++ G
Sbjct: 24876 VMAVNKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEG 24935
Query: 1752 YRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVV--- 1808
Y + KE K + V+GL YE V A P++ V
Sbjct: 24936 YILEKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYR 24995
Query: 1809 --TTLENVSPPRRARVTDATETTITISWRTKT----ETITGF--QVDAVPANGQTPIQRT 1860
L PP +VTD + ++++++W + G+ +V A+ T
Sbjct: 24996 ACDALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPP 25055
Query: 1861 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAS 1900
+ +T+T L+ T+Y + +N P + S
Sbjct: 25056 TGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGS 25095
Score = 101 bits (252), Expect = 8e-21
Identities = 308/1501 (20%), Positives = 533/1501 (35%), Gaps = 204/1501 (13%)
Query: 624 NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNS--YTIKGLKPGVVYE 678
NS + W P+ S I +YIL R K S RW + ++ + + GL G YE
Sbjct: 28166 NSITLTWARPESDGGSEIQQYILERREKKST-RWVKVISKRPISETRFKVTGLTEGNEYE 28224
Query: 679 GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
+++ G + PV P P V VT+ + ++ +
Sbjct: 28225 FHVMAENAAGVGPASGIS-RLIKCREPVNP--------PGPPTVV---KVTDTSKTTVSL 28272
Query: 739 SW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQIS 794
W + G+ +E ++ GD + T + DL G +Y V I+
Sbjct: 28273 EWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAIN 28332
Query: 795 EDGEQSLILSTSQTTAPD--APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGS 852
G+ T A D P+ +D + VVR Y+ +P+ S
Sbjct: 28333 GAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWS 28392
Query: 853 STELNLPETANSVTLSDLQPGVQYNIT-------IYAVEENQESTPVVIQQETTGTPRSD 905
+ NL A+ T N VE N S + + TP
Sbjct: 28393 KPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP- 28451
Query: 906 TVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
P + F +VT T+MW P + + Y V+ + +R F
Sbjct: 28452 ----PGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIF 28507
Query: 962 AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ----TTKLDAPTNLQFVNETDSTVLVRW 1017
+V L+ GV YYF+V AV+ +P + T + P L V+ + S+ ++ W
Sbjct: 28508 -KVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAW 28566
Query: 1018 TPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEY---------- 1062
P ++ITGY L + ++G G + + + L +EY
Sbjct: 28567 LKPDHDGGSRITGYLLE--MRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDA 28624
Query: 1063 -------TVSLVAIKGNQESPKA--TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI 1113
S V IK Q P A TG+ L + P+ +V I+ PAP++
Sbjct: 28625 GYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVP-----ISGRPAPKV 28679
Query: 1114 GFKL-GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT 1172
+KL +R + T D ++ V G Y + + + + V+
Sbjct: 28680 TWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIG 28739
Query: 1173 PLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQ 1229
P T ++ +SW + +IT Y + + + V Q
Sbjct: 28740 RPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQ 28799
Query: 1230 SSCTFDNLSPGLEYNVSV-----YTVKDDKESVPISDTIIPAVPP--PTDLRFTNIGPDT 1282
T +L+ +EY+ V + V ES PI P VPP PT ++ +
Sbjct: 28800 IKVT--HLTKYMEYSFRVSSENRFGVSKPLESAPII-AEHPFVPPSAPTRPEVYHVSANA 28856
Query: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEED----VAELSISPSDNAVVLTNLLPGTE----- 1333
M + W P D + ++ Y K E + V E + + +T L+ G E
Sbjct: 28857 MSIRWEEPYH-DGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRT 28915
Query: 1334 YVVSVSSVYEQHE-STPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGY 1388
Y ++ + V + E S P+ + +D+P + +D+T ++ ++ W AP + + GY
Sbjct: 28916 YALNAAGVSKASEASRPIMAQNP--VDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGY 28973
Query: 1389 RIRHHPEHFSGRPREDRVPH---SRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS 1445
I P G R + + S N T+T L+ G Y ++A N + G +S
Sbjct: 28974 IIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNA--AGVISKGSES 29031
Query: 1446 TVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI 1505
T RD + D + + GG + G K
Sbjct: 29032 TGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLC 29091
Query: 1506 SGLKPGVDYT----ITVYAVTGRGDS---------PASSKPISINYRTEIDKP---SQMQ 1549
K + YT V R DS + +K +S+ + +D P ++
Sbjct: 29092 E--KVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV-LDSPGPCGKLT 29148
Query: 1550 VTDVQDNSISVKW-LP---SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPT 1605
V+ V ++ W LP + +T Y V + +T+ + + +EG PT
Sbjct: 29149 VSRVTQEKCTLAWSLPQEDGGAEITHYIV----------ERRETSRLNW--VIVEGECPT 29196
Query: 1606 VEYVVS-----------VYAQNPSG-----ESQPLVQTAVTNIDRPKGL-AFTDVDVDSI 1648
+ YVV+ V A N G ES+P+V I P G+ + I
Sbjct: 29197 LSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHI 29256
Query: 1649 KIAWESPQ----GQVSRYRVTYSSPED----GIHELFPAPDGEEDTAELQGLRPGSEYTV 1700
I W P+ ++S Y V + +++ + D ++ L G +Y
Sbjct: 29257 IIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYD---TRLKVTSLMEGCDYQF 29313
Query: 1701 SVVALHDDMESQP------LIGTQSTAIPAPTDL-KFTQVTPTSLSAQWTPP----NVQL 1749
V A++ S+P + + + P P + T S+S WT P +
Sbjct: 29314 RVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDI 29373
Query: 1750 TGYRVRVTPKEKTGPMK-EINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV- 1807
GY + + K+ + N ++ V L + KY V A+ S ++ +
Sbjct: 29374 VGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIA 29433
Query: 1808 -VTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPA-----NGQTPIQRTI 1861
+ +E + P + D + T+TI + P G R I
Sbjct: 29434 EIEPVERIEIP-DLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAI 29492
Query: 1862 KPDVRSYTITGLQPGTDYKIYLYTL---NDNARSSPVVIDASTAIDAP-SNLRFLATTPN 1917
SY++ + Y YT+ N + + S V+ P +++ + +
Sbjct: 29493 IDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRD 29552
Query: 1918 SLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYV 1973
S+ ++W+ P A + YI++ + + V + T I+GL GT Y V
Sbjct: 29553 SVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTV-TTKCSKTLYRISGLVEGTMYYFRV 29611
Query: 1974 I 1974
+
Sbjct: 29612 L 29612
Score = 98.2 bits (243), Expect = 8e-20
Identities = 288/1429 (20%), Positives = 523/1429 (36%), Gaps = 305/1429 (21%)
Query: 624 NSHPIQWNAPQPSHISKYILRW---RPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQ 680
N+ I+W P SK I W + +N++ KE +P +Y + GL G+ Y+ +
Sbjct: 28855 NAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFR 28914
Query: 681 LISIQQYGHQEVTRFDFTTTSTSTPVTS-NTVTGETTPFSPLVATSESVTEITASSFVVS 739
++ G + + S P+ + N V P VT++T S+ +
Sbjct: 28915 TYALNAAGVSKASE-------ASRPIMAQNPVDAPGRP---------EVTDVTRSTVSLI 28958
Query: 740 WVSAS----DTVSGFRVEYELSEEGDEPQYLDLPSTATSVN---IPDLLPGRKYIVNVYQ 792
W + + V G+ +E + E + ++L T S N + L G Y V
Sbjct: 28959 WSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLA 29018
Query: 793 ISEDGEQSLILSTSQTTAPD------APPDPTVD-QVDDTSIVVRWSRPQAPITGYRIVY 845
+ G +I S++T P APP +D ++ + +R G +V
Sbjct: 29019 KNAAG---VISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIR--------AGSDLVL 29067
Query: 846 SPSVEGS----------STELNLPETANS----------VTLSDLQPGVQYNITIYAVEE 885
+V G EL+L E + + D +Y +T+
Sbjct: 29068 DAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASG 29127
Query: 886 NQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDV 941
+ + +V ++ G TV VT K T+ W+ P+ + +T Y V+
Sbjct: 29128 TKAVSVMVKVLDSPGPCGKLTVS--------RVTQEKCTLAWSLPQEDGGAEITHYIVE- 29178
Query: 942 IPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYY-----------FKVFAVS-HGR----E 985
R SR + V G P ++Y F+V AV+ +G E
Sbjct: 29179 -----------RRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVE 29227
Query: 986 SKPLTAQQTTKLDAPTNL-QFVNETDSTVLVRWTPPRA----QITGYRLTVGLTRRGQPR 1040
S+P+ A+ + + +P + + V ++++WT P + +I+ Y V + R
Sbjct: 29228 SEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNY--LVDKREKKSLR 29285
Query: 1041 QYNVGPSVSKYPLR----NLQPASEYTVSLVAIK--GNQESPKATGVFTTLQPGSSIPPY 1094
V Y R +L +Y + A+ GN E +A+ + +P
Sbjct: 29286 WTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREP------- 29338
Query: 1095 NTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTP----GVEYV 1150
++TP P PS APR V + SI ++ P G + V
Sbjct: 29339 -----------SYTPGP---------PS----APRVVDTTKHSISLAWTKPMYDGGTDIV 29374
Query: 1151 -YTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDIT----- 1204
Y +++ QE+D +V H A T+ T PD+
Sbjct: 29375 GYVLEM----QEKDTDQWYRV----------HTNA-------TIRNTEFTVPDLKMGQKY 29413
Query: 1205 GYRITTTPTNG--QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDT 1262
+R+ G + S+ E+ ++ L+ L+ V++ + V +S
Sbjct: 29414 SFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGR 29473
Query: 1263 IIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNA 1322
PPP +TW+ IDL + + + E + L +
Sbjct: 29474 -----PPPV-------------ITWSKQ-GIDLASRAI----IDTTESYSLLIVDK---- 29506
Query: 1323 VVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR 1382
N +Y + + + +T L T P+ + +++ +S T+ W P
Sbjct: 29507 ---VNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPS-VKVKEVSRDSVTITWEIPT 29562
Query: 1383 ----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITL---TNLTPGTEYVVSIVALNGRE 1435
A + Y + E R + ++ S TL + L GT Y ++
Sbjct: 29563 IDGGAPVNNYIV----EKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLP----- 29613
Query: 1436 ESPLLIGQQSTVSD---------VPRDLEVVAATPTSLLISWDAPAVT----VRYYRITY 1482
E+ IG+ SD VP LEVV T +++ ++W+ P + Y +
Sbjct: 29614 ENIYGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEA 29673
Query: 1483 GETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEI 1542
+ G ++ T+ + T++ L G Y + A +G S ++ +
Sbjct: 29674 CKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLR 29733
Query: 1543 DKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGP------------------ 1584
P+ + ++ + +I V P+ PV P G P
Sbjct: 29734 VLPT-IDLSTMPQKTIHV---PAGRPVE----LVIPIAGRPPPAASWFFAGSKLRESERV 29785
Query: 1585 ---TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKG--LA 1639
T TK A E TI + T EY + + +N +G + ++ + + P +
Sbjct: 29786 TVETHTKVAKLTIRETTI---RDTGEYTLEL--KNVTGTTSETIKVIILDKPGPPTGPIK 29840
Query: 1640 FTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEE---DTAELQGLRPGS 1696
++D SI I+WE P+ Y + H P E T + L G+
Sbjct: 29841 IDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGN 29900
Query: 1697 EYTVSVVALH-----DDMESQPLIGTQSTAIPAPTD-LKFTQVTPTSLSAQWTPPN---- 1746
EY V A + ++S+ + S IP P + L+ V+ ++ W PP
Sbjct: 29901 EYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGG 29960
Query: 1747 VQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVS-GLMVATKYEVSVYALK---DTLTSR 1802
Q+TGY V + + +N P + + S GL +YE V A+ SR
Sbjct: 29961 SQVTGYIVE-RKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSR 30019
Query: 1803 PAQGVVTTLENVSPP---RRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQT 1855
P++ +V ++ ++PP + RVTD T T+++++W + +TG+ ++ +
Sbjct: 30020 PSKPIVA-MDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHE 30078
Query: 1856 PIQ-RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI 1903
+ T +R YT+T L G +Y+ + N P + + +
Sbjct: 30079 WTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKV 30127
Score = 97.1 bits (240), Expect = 2e-19
Identities = 340/1573 (21%), Positives = 568/1573 (36%), Gaps = 223/1573 (14%)
Query: 619 TPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
T S +S +QWN P S + Y L + +NS+ K P + GL+ GV
Sbjct: 22350 TLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGV 22409
Query: 676 VYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASS 735
YE ++ + G P + P P E++ +T +S
Sbjct: 22410 EYEFRVSAENIVG-------------IGKPSKVSECYVARDPCDP-PGRPEAII-VTRNS 22454
Query: 736 FVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVY 791
+ W ++G+ VE + EG + T + L+ +Y V
Sbjct: 22455 VTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVI 22514
Query: 792 QISEDGEQSLIL-STSQTTAPDA--PPDPTVDQVDDTSIVVRWS---RPQAPITGYRIVY 845
+ G S ST TA D PP ++D +IVV + A I G I
Sbjct: 22515 ARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPI-- 22572
Query: 846 SPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
P+++ + L TA + +D + + +S +++ + RS
Sbjct: 22573 -PTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV-----DSGNYILKAKNVAGERS 22626
Query: 905 DTV-------PSPRDLQFV--EVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP 955
TV P P + V VT K T+ W PP + D+I + RL
Sbjct: 22627 VTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPP---LQDGGSDIINYIVERRETSRLV 22683
Query: 956 IS------RNTFAEVTGLSPGVTYYFKVFAVS-----HGRESKPLTAQQTTKL-DAPTNL 1003
+ + +VT L G Y F++ AV+ ES+P+ A+ + DAP
Sbjct: 22684 WTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAP 22743
Query: 1004 QFVNETDSTVLVRWTPPRA----QITGYRLTV----GLTRRGQPRQYNVGPSVSKYPLRN 1055
+ T +++V W P + +I GY L G+ R + + +G +
Sbjct: 22744 EVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGI-RWTRCHKRLIGELRLRVTGLI 22802
Query: 1056 LQPASEYTVSLVAIKGNQE-SPKAT---GVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
E+ VS G E SP + +PG P ++T +++ ++W+
Sbjct: 22803 ENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPI 22862
Query: 1112 RIGF---------KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD---G 1159
G K V + + +I V L EY + I + G
Sbjct: 22863 YDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVG 22922
Query: 1160 QERDAPIVNKVVTPL-SPPTNLHLEANPDTGV-------LTVSWERSTTPDITGYRITTT 1211
+ D P V L +P +L LE + L V + TP++ ++
Sbjct: 22923 EHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKV--- 22979
Query: 1212 PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV----KDDKESVPISDTIIPAV 1267
+G+ ++ V + +S DN++ Y+ YT+ +S ++ ++
Sbjct: 22980 --DGEIRDAAIIDVTSSFTSLVLDNVN---RYDSGKYTLTLENSSGTKSAFVTVRVLDTP 23034
Query: 1268 PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAELSISPSDNAVV 1324
PP +L+ T I D++ +TW PP +D + + Y K E + A + + N+
Sbjct: 23035 SPPVNLKVTEITKDSVSITW-EPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWK 23093
Query: 1325 LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL----DSPTGIDFSDITANSFTVHWIA 1380
+ L G Y V++ E P + + P I D+T NS ++ W
Sbjct: 23094 IDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTK 23153
Query: 1381 PR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436
P + I Y + +H RV + +TNLT G EY+ +VA+N +
Sbjct: 23154 PEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQ--AVITNLTQGEEYLFRVVAVNEKGR 23211
Query: 1437 S-PLLIGQQSTVSDVPRDLEVVAA-TPTSLLISWD----APAVTVRYYRITYGETGGNSP 1490
S P + D+ + +V A + S+ + D P IT+ + G P
Sbjct: 23212 SDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDG--LP 23269
Query: 1491 VQEFT---VPGSKSTATIS----GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
+++ T V S T+S G Y ITV V G+ K SI T +D
Sbjct: 23270 LKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQ-------KTASIEIVT-LD 23321
Query: 1544 KP----SQMQVTDVQDNSISVKWLP----SSSPVTGYRV-----TTTPKNGPGPTKTKTA 1590
KP ++ DV SI++ W P +T Y V TTT + T +T
Sbjct: 23322 KPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTT 23381
Query: 1591 GPDQTEMTIEGLQPTVEYVVSVYAQNPSG-----ESQPLVQTAVTNIDRPKGLAF-TDVD 1644
+ + L+ EY ++A+N G ES P+V P G F T +
Sbjct: 23382 ------LKVTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAIS 23435
Query: 1645 VDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE---EDTA-ELQGLRPGSEYTV 1700
DS+ I W P + Y + + + DT + Q L G EY
Sbjct: 23436 KDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEF 23495
Query: 1701 SVVALHDDMESQPLIGTQSTAIPAPTDLKFT----QVTPTSLSAQWTPP----NVQLTGY 1752
V A + + ++ P D T V ++ QWT P +TGY
Sbjct: 23496 RVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGY 23555
Query: 1753 RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT-LTSRPAQ--GVVT 1809
V MK + VSGL +YE V A S+P+ G +T
Sbjct: 23556 IVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPIT 23615
Query: 1810 TLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYT 1869
+ V PR + +T + + T F+++A P ++ D
Sbjct: 23616 AKDEVELPRISMDPKFRDTIVVNAGET-------FRLEADVHGKPLPTIEWLRGDKEIEE 23668
Query: 1870 ITGLQ-PGTDYKIYL------------YTLNDN----ARSSPV---VIDASTAIDAPSNL 1909
+ TD+K L Y L + ++S PV V+D + P +
Sbjct: 23669 SARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGP--V 23726
Query: 1910 RFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEP 1965
+ T ++W PP + I+ Y+++ ++ S V +T L
Sbjct: 23727 QVTGVTSEKCSLTWSPPLQDGGSDISHYVVE-KRETSRLAWTVVASEVVTNSLKVTKLLE 23785
Query: 1966 GTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTH 2025
G EY ++A+ EPL + P L+ P P+ L+V + + + V
Sbjct: 23786 GNEYVFRIMAVNKYGVGEPL------ESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCW 23839
Query: 2026 PGYDTGNGIQLPG 2038
D+ G ++ G
Sbjct: 23840 NRPDSDGGSEIIG 23852
Score = 94.0 bits (232), Expect = 2e-18
Identities = 154/662 (23%), Positives = 253/662 (38%), Gaps = 93/662 (14%)
Query: 1447 VSDVP---RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
V DVP R+LEV + ++W+ P I Y + + + + ++ +
Sbjct: 13086 VIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAES 13145
Query: 1504 ---TISGL-KPGVDYTITVYAVT--GRGDSPASSKPISINYRTEIDKPS-QMQVTDVQDN 1556
T++GL K GV+Y V A G G+ + P+ + ++ P + +TDV
Sbjct: 13146 CEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRF 13205
Query: 1557 SISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV 1612
+S+ W P + +T Y + K T + T+ + EY V
Sbjct: 13206 GVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRV 13265
Query: 1613 YAQNPSGESQPLVQTAVTN----IDRPK---GLAFTDVDVDSIKIAWESPQGQVSRYRVT 1665
AQN G +P T I+RP L +D S+++ WE P +
Sbjct: 13266 RAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILG 13325
Query: 1666 Y--SSPEDGIH-------ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIG 1716
Y E+G +L P E T ++ GL G++Y V A + S P
Sbjct: 13326 YIIERCEEGKDNWIRCNMKLVP-----ELTYKVTGLEKGNKYLYRVSAENKAGVSDP--- 13377
Query: 1717 TQSTAIPAPTDLKFTQVTPT-SLSA-----QWTPPN-----VQLTGY-RVRVT-----PK 1759
+ I P V PT LSA + PN V TGY R T
Sbjct: 13378 ---SEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKV 13434
Query: 1760 EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPP 1817
+TG ++ + +V+S + + + +Y LK + G V + S P
Sbjct: 13435 LETGDRVKMKTLSAYAELVISP---SERSDKGIYTLKLENRVKTISGEIDVNVIARPSAP 13491
Query: 1818 RRARVTDATETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGL 1873
+ + D T+ ++ ++W + +TG+ V+ + +T + +T+ L
Sbjct: 13492 KELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDL 13551
Query: 1874 QPGTDYKIYLYTLNDNARSSPVVIDA-------STAIDAPSNLRFLATTPNSLLVSWQPP 1926
G +Y + N P +D +T D P N+++ T NS+ ++W PP
Sbjct: 13552 VQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPP 13611
Query: 1927 R----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 1982
+ +RI GYI++ GS P T+ +TGLE G Y V AL S
Sbjct: 13612 KNDGGSRIKGYIVERCPRGSDKWVACGEP-VAETKMEVTGLEEGKWYAYRVKALNRQGAS 13670
Query: 1983 EPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQ 2042
+P + T+E+ + T P + LDV T G I+LP T
Sbjct: 13671 KP---SRPTEEIQAVDTQEAPEI----FLDVKLLAGLT-------VKAGTKIELPATVTG 13716
Query: 2043 QP 2044
+P
Sbjct: 13717 KP 13718
Score = 94.0 bits (232), Expect = 2e-18
Identities = 327/1598 (20%), Positives = 576/1598 (36%), Gaps = 255/1598 (15%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W+ P+ S I+ +I+ R + W++ I + I GL G Y+ ++I+
Sbjct: 15215 LNWSDPEDDGGSEITGFIIE-RKDAKMHTWRQP-IETERSKCDITGLLEGQEYKFRVIAK 15272
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV--- 741
++G PV + P + TE T S+ + W
Sbjct: 15273 NKFG-------------CGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPR 15319
Query: 742 -SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQS 800
+ + G+ +E ++ D + TS + +L + Y V ++E GE
Sbjct: 15320 SNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESE 15379
Query: 801 LILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWSRP---QAPITGYRIVYSPSVEGSST 854
L + D P PT+ V +I V+ P A +TG + P +E S
Sbjct: 15380 PSLPLNVVIQDDEVP-PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPM---PKIEWSKN 15435
Query: 855 E--LNLPETANSVTLSDLQPG-VQYNITI-YAVEENQESTPVVIQQETTGTPRS------ 904
E + P A +T ++ + ++I AV E++ + V R+
Sbjct: 15436 ETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVY 15495
Query: 905 DTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
D PR+L ++ + W P S +T Y +D + + + NT
Sbjct: 15496 DRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVT---NT 15552
Query: 961 FAE----VTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKLDAPTNL-QFVNETD 1010
E + L P Y F+V + +S +S + Q +L P + + T
Sbjct: 15553 AVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTK 15612
Query: 1011 STVLVRWTPP----RAQITGYRLTVGLTRRGQPRQY----------NVGPSVSKYPLRNL 1056
++LV WTPP + ITGY L +R + Y VG ++ + L
Sbjct: 15613 GSMLVSWTPPLDNGGSPITGY----WLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRL 15668
Query: 1057 QPASEYTVSLVAIKG------NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
+Y +AI ++ S PG P + T+++I + W P
Sbjct: 15669 LEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPP 15728
Query: 1111 PRIGFKLGVRPSQG--GEAPREVTSD------------SGSIVVSGLTPGVEYVYTIQVL 1156
K G P +G E E T+D + VV L +Y + ++ +
Sbjct: 15729 A----KDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAV 15784
Query: 1157 RD-GQERDAPIVNKV-VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT- 1213
+ G+ + ++ T + + ++ ++ + + P + R T +
Sbjct: 15785 NEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSW 15844
Query: 1214 --NGQQGNSLEEVVH---ADQSSCTFDNLSPGL----------EYNVSVYTVKDDKESVP 1258
+G+ ++++ VH D T +N S + +Y+++ K +++
Sbjct: 15845 EFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKN-KAGQKTAN 15903
Query: 1259 ISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEED-VAELSIS 1317
++ PP DL+ ++I + R++W P D + + Y K D A ++
Sbjct: 15904 CRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDD-DGGDRIKGYVIEKRTIDGKAWTKVN 15962
Query: 1318 P--SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL-------DSPTGIDFSD 1368
P V+ +LL +Y V + P+ Q+T D P +
Sbjct: 15963 PDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGL 16022
Query: 1369 ITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRED-RVPHSRN----SITLTNLT 1419
IT N+ + W P+ + +T Y + +G +E R + R+ T+ +L
Sbjct: 16023 ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLV 16082
Query: 1420 PGTEYVVSIVALN--GREESPLLIG-------QQSTVSDVPRDLEVVAATPTSLLIS-WD 1469
G EY + A+N G + +G D+ +EV T +++
Sbjct: 16083 EGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKG 16142
Query: 1470 APAVTVRYYRITYGETGGNSPVQEFT-----VPGSKSTATISGLKPGVDYTITVYAVTGR 1524
P T+ +++ + PV T V T I + T+ AV
Sbjct: 16143 VPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNL 16202
Query: 1525 GDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPK 1579
G +SK + +N P ++ V + +++ W P S +T Y +
Sbjct: 16203 G---TASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREA 16259
Query: 1580 NGPGPTKT---KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT--NI-- 1632
N KT ++ P + TI L EYV + AQN G +PL T N+
Sbjct: 16260 N----RKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFS 16315
Query: 1633 --DRPKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDT 1686
P + V +S+ + WE P+ V+ Y + +D + + + +
Sbjct: 16316 VPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGY---WLEMKDTTSKRWKRVNRDPIK 16372
Query: 1687 A-------ELQGLRPGSEYTVSVVALH------DDMESQPLIGTQSTAIPAPTDLKFTQV 1733
A ++ GL GS+Y V A++ + S P A P P K T
Sbjct: 16373 AMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDW 16432
Query: 1734 TPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 1789
T +S +W+PP ++TGY V + K K + + +VV+GL Y+
Sbjct: 16433 TKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYK 16492
Query: 1790 VSVYALKDTLTSRPAQGVVTTLEN----VSPPRR--ARVTD----------------ATE 1827
V A+ P + V +E VSP + A V D + +
Sbjct: 16493 FRVRAVNIAGIGEPGE-VTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGK 16551
Query: 1828 TTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDV--RSYTITGLQPGTDYKIYLYT 1885
T++W T+ P + TI+ S I Q L
Sbjct: 16552 PPPTVTWNMNERTL--------------PQEATIETTAISSSMVIKNCQRSHQGVYSLLA 16597
Query: 1886 LNDNARSSPVVIDASTAIDAPSNLRFLA--TTPNSLLVSWQPPR----ARITGYIIKYEK 1939
N+ +I + P FLA T S ++W P + IT Y+I EK
Sbjct: 16598 KNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVI--EK 16655
Query: 1940 PGSPPREVVPRPRPGVTE-ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLV 1998
S R P + AT+ GL G Y + IA +N+ P + + + + +
Sbjct: 16656 RESDRRAWTPVTYTVTRQNATVQGLIQGKAY-FFRIAAENSIGMGPFVETSEALVIREPI 16714
Query: 1999 TLPHPNLHGPEILDVPSTVQKTPFVT--HPGYDTGNGI 2034
T+P PE L+V + T +T P YD G+ I
Sbjct: 16715 TVP----ERPEDLEVKEVTKNTVTLTWNPPKYDGGSEI 16748
Score = 94.0 bits (232), Expect = 2e-18
Identities = 304/1555 (19%), Positives = 549/1555 (35%), Gaps = 206/1555 (13%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W P S I+ Y+L R +V K P + GL+ G YE ++ +I
Sbjct: 19506 VSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAI 19565
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW---- 740
+ G + + S + P V + T SS +SW
Sbjct: 19566 NKAGPGKPSD------------ASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPA 19613
Query: 741 VSASDTVSGFRVEYELSEEGDEPQYLDLPST--ATSVNIPDLLPGRKYIVNVYQISEDGE 798
+ G+ VE + + + D +LP T + L+ +Y VY +++ G
Sbjct: 19614 YDGGSPIIGYLVEVKRA-DSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIG- 19671
Query: 799 QSLILSTSQTTAPD--------APPDPTVDQVDDTSIVVR---WSRPQAPITGYRIVYSP 847
+ + PD PP+ +D ++++R R P+ G P
Sbjct: 19672 -----YSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRP---PP 19723
Query: 848 SVEGSSTELNLPETAN-SVTLSDLQPGV-----------QYNITIYAVEENQESTPVVIQ 895
+ S +NL + + +D + +Y +T+ +E T VV
Sbjct: 19724 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 19783
Query: 896 QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHG 951
+T G P + TV E++ + W PP S + Y V
Sbjct: 19784 LDTPGPPVNVTVK--------EISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWST 19835
Query: 952 QRLPISRNTFAEVTGLSPGVTYYFKVFAVSH---GRESKPLTAQQTTKLDAP-TNLQFVN 1007
S+ +F V L G +Y+F+VFA + G + A + ++ P +L+ +
Sbjct: 19836 VTTECSKTSF-RVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRS 19894
Query: 1008 ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYT 1063
+ S+ + W P ++I GY + LT + ++ S+ +Y ++L EYT
Sbjct: 19895 VSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMKSLSL-QYSAKDLTEGKEYT 19952
Query: 1064 VSLVAIKGNQE-SPKATGVFT---TLQPG---SSIPPYNTEVTETT-----IVITWTPAP 1111
+ A N E +P V + P +P E + I I PAP
Sbjct: 19953 FRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAP 20012
Query: 1112 RIGFKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
+ +K G P + E ++ + +++V YTI + ++ I KV
Sbjct: 20013 SVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKV 20072
Query: 1171 VTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
V PT +T+ W + +IT Y + + + + V
Sbjct: 20073 VGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAV-- 20130
Query: 1228 DQSSCTFDNLSPGLEYNVSV-----YTVKDDKESVPI---SDTIIPAVPPPTDLRFTNIG 1279
+++ L G+EY V Y V + +S PI +P PPP ++ ++
Sbjct: 20131 QKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNI--VDVR 20188
Query: 1280 PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVA-----ELSISPSDNAVVLTNLLPGTEY 1334
D++ +TW P + + K + + I D V T L G EY
Sbjct: 20189 HDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV--TGLTEGLEY 20246
Query: 1335 VVSVSSVYEQHESTPLRGRQKT----GLDSPTGIDFSDITANSFTVHWIAPR----ATIT 1386
V ++ P + +D P + +IT NS T+ W P+ +T
Sbjct: 20247 EFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLT 20306
Query: 1387 GYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN--GREESPLLIGQQ 1444
GY + + + V + T+T+L G +Y I A N G +P +
Sbjct: 20307 GYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAP----SE 20362
Query: 1445 STVSDVPRDLEVVAATPTSLLISWDAPAVTVR----------------YYRITYGETGGN 1488
ST + + +D PT +L +T++ + ++ + G +
Sbjct: 20363 STETIICKD---EYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKD 20419
Query: 1489 SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQM 1548
+ T S T+++ +K Y +T + + + P +
Sbjct: 20420 IRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPV 20479
Query: 1549 QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
++++V ++ W P SP+ Y + + T + + +Q
Sbjct: 20480 EISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQG 20539
Query: 1605 TVEYVVSVYAQNPSGESQPLVQTAVTNIDR------PKGLAFTDVDVDSIKIAWESP--- 1655
EY+ V A N G+ +P+ V +DR P+ ++V ++ ++W+ P
Sbjct: 20540 N-EYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDD 20598
Query: 1656 -QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVA-----LHDDM 1709
+++ Y V + + ++ GL+ GS Y V A +
Sbjct: 20599 GGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPS 20658
Query: 1710 ESQPLIGTQSTAIP--APTDLKFTQVTPTSLSAQWTPPN----VQLTGYRVRVTPKEKTG 1763
E+ + + A P P++ T T S S W P+ +++TGY V +K G
Sbjct: 20659 EASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGY---VVEHQKVG 20715
Query: 1764 PMKEI----NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRR 1819
I A + VV L KY + A+ D PA V+ +E V
Sbjct: 20716 DEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPA--VIPDVEIVEREMA 20773
Query: 1820 ARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIK-------PDVRSYTITG 1872
E T+ R + PA T + I + S+T+
Sbjct: 20774 PDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTLLI 20833
Query: 1873 LQPGTDYKI--YLYTLNDNARSSPVVIDASTAIDAPS---NLRFLATTPNSLLVSWQPP- 1926
+ Y ++ T+ + A ++ +D P NLR T +S+ + W P
Sbjct: 20834 IPECNRYDTGKFVMTIENPAGKKSGFVNV-RVLDTPGPVLNLRPTDITKDSVTLHWDLPL 20892
Query: 1927 ---RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 1983
+RIT YI++ ++ + + +TGL G EY V+A E
Sbjct: 20893 IDGGSRITNYIVE-KREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGE 20951
Query: 1984 PLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPG 2038
P +T E + P P P+ L++ + T + P G ++ G
Sbjct: 20952 P----TETTEPVKASEAPSP----PDSLNIMDITKSTVSLAWPKPKHDGGSKITG 20998
Score = 93.6 bits (231), Expect = 2e-18
Identities = 287/1440 (19%), Positives = 522/1440 (36%), Gaps = 175/1440 (12%)
Query: 675 VVYEGQLISIQQYGHQEVTRFDFTTTSTS--TPVTSNTVTGETT--PFSPLVATSESVTE 730
+ E I++++ + R++ T ++S T N V + P P+V +++
Sbjct: 26527 ITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVV-----ISD 26581
Query: 731 ITASSFVVSWVSAS-DTVSGFRVEYELSEEGDEPQYLDLPSTA--TSVNIPDLLPGRKY- 786
IT S + W D S L E + ++ +T T + + L G +Y
Sbjct: 26582 ITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQ 26641
Query: 787 ----IVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYR 842
N + IS+ + + + T P P P V V SI V W P + G
Sbjct: 26642 FRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVS--NGGS 26699
Query: 843 IVYSPSVEGSSTELNLPETANSVTL-------SDLQPGVQYNITIYAVEENQESTPVVIQ 895
V +E L + AN + + + + G+ Y +YA P
Sbjct: 26700 AVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKP---S 26756
Query: 896 QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHG 951
+ D PR+++ +++ V++ W P S +TGY V+ +LP
Sbjct: 26757 HPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVE--RRDLPDGRW 26814
Query: 952 QRLPISRNTFAE--VTGLSPGVTYYFKVFAVSH-GRESKPL-TAQQTTKLDAPTNLQFVN 1007
+ + T + ++GL+ Y F+VFA + G S P T +D+
Sbjct: 26815 TKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDL 26874
Query: 1008 ETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--RQYNVGPSVSKYPLRNLQPASEYTVS 1065
+ T +V++ T +L G++ + P Y + L ++ ++
Sbjct: 26875 PLEYTEVVKYRAG----TSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASI 26930
Query: 1066 LV-------------AIKGNQESPKATGVFTTL-QPGSSIPPYNTE-VTETTIVITW-TP 1109
L+ ++ S AT L +PG P + VT I + W P
Sbjct: 26931 LIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPP 26990
Query: 1110 APRIGFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQVLR-----D 1158
A G K+ + E R V S + I + + G EY++ ++ + +
Sbjct: 26991 ADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGE 27050
Query: 1159 GQERDAPIV-NKVVTPLSP--PTNLHLEANPDTGVLTVSWERSTT---PDITGYRITTTP 1212
E D+ + N VTP P P + N +TV W R DI+GY +
Sbjct: 27051 PLESDSVVAKNAFVTPGPPGIPEVTKITKNS----MTVVWSRPIADGGSDISGYFLEKRD 27106
Query: 1213 TNGQQG-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV--------KDDKESVPISDTI 1263
L+E + + T L+ +Y V V + E +D I
Sbjct: 27107 KKSLGWFKVLKETIRDTRQKVT--GLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPI 27164
Query: 1264 IPAVPPPTDLRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEE-DVAELSISPS 1319
P PP +R + ++ + W+ P +T ++V + EE
Sbjct: 27165 DPP-GPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVR 27223
Query: 1320 DNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ----KTGLDSPTGIDFSDITANSFT 1375
V++NL PG Y VS+V + P+ + K L++P ID S
Sbjct: 27224 TTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPE-IDLDVALRTSVI 27282
Query: 1376 VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSI---------TLTNLTPGT--EY 1424
+ ++ R P + ++ +R SI T+ +T +Y
Sbjct: 27283 AKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKY 27342
Query: 1425 VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1484
+++I G +S + + + L+V + ++ + WD P + I Y
Sbjct: 27343 ILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 27402
Query: 1485 TGGNSPVQEFTVPGSKSTATISGL-----KPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
++ + ++V K ++T L K + + G G+ +++P+
Sbjct: 27403 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVK---A 27459
Query: 1540 TEIDKP-SQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594
E+ P + + D S+ + W S +T Y V + G G AG +
Sbjct: 27460 AEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVV---ERKGKGEQTWSHAGISK 27516
Query: 1595 T-EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFT-DVDVDSIKIAW 1652
T E+ + L+ V+A+N G S P+ +T K L T +VD+ I A
Sbjct: 27517 TCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPIT----VKELIITPEVDLSDIPGAQ 27572
Query: 1653 ESPQ-GQVSRYRVTY-SSPEDGIHEL---FPAPDGE-------EDTAELQGLRPGSEYTV 1700
+ + G + Y P+ I L P + E E+ L E+
Sbjct: 27573 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGG 27632
Query: 1701 SVVALHDDMESQPLIGTQSTAIPAPT----DLKFTQVTPTSLSAQWTPP----NVQLTGY 1752
+ D+ + + + P+ ++F ++ S+ W P ++T Y
Sbjct: 27633 KYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCY 27692
Query: 1753 RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLE 1812
+ +T K + + ++ V L+ +Y+ V A S+P + +
Sbjct: 27693 SIEKRETSQTN-WKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAK 27751
Query: 1813 N----VSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKP- 1863
+ PP + + + T ++++W +TGF V+ N + P
Sbjct: 27752 HQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPI 27811
Query: 1864 DVRSYTITGLQPGTDYKIYLYTLNDNARSSP----VVIDASTAIDAPSNLRFLATTPNSL 1919
R Y TGL G DY+ +Y N SSP A + +D P ++ T ++
Sbjct: 27812 SGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETI 27871
Query: 1920 LVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 1975
+ W PP ++I GY I+ ++ G+ + T+TGL PG Y +IA
Sbjct: 27872 TLKWNPPLRDGGSKIVGYSIE-KRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIA 27930
Score = 91.3 bits (225), Expect = 1e-17
Identities = 329/1588 (20%), Positives = 528/1588 (33%), Gaps = 253/1588 (15%)
Query: 589 CYGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPK 648
C R GE+ S + V + + + P P PI P H++ + W+P
Sbjct: 17573 CLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTG-PINILDVTPEHMT---ISWQPP 17628
Query: 649 NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQL-----ISIQQYGHQEVTRFDFTTTSTS 703
G I + + GVV G I Q G + V R
Sbjct: 17629 KDDGG--SPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGV 17686
Query: 704 TPVTSNTVTGETTPFSPLVATSESV-TEITASSFVVSWV----SASDTVSGFRVEYELSE 758
P +T T FSP + V T+IT ++ VSW ++G+ +E
Sbjct: 17687 GPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERR-EV 17745
Query: 759 EGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTA--PDAPPD 816
G + P + L G Y V+ + G S+ A P PP
Sbjct: 17746 TGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPG 17805
Query: 817 PTV-----DQVDDTSIVVRWSRPQA----PITGYRIVYSPSVEGSSTELNLPETANSVT- 866
P + D+ +T+ +V W++P + PI GY + +N E
Sbjct: 17806 PPINPKLKDKSRETADLV-WTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQCAF 17864
Query: 867 -LSDLQPGVQYNITIYAVE-----ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTD 920
+ L G +Y I A E +E VI ++ P + + RD+ V V
Sbjct: 17865 RVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRVGQ 17924
Query: 921 V-----------KVTIMWTPPESA-VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLS 968
+ I WT V RVD+I Q LP E
Sbjct: 17925 TIRILARVKGRPEPDITWTKEGKVLVREKRVDLI---------QDLPRVELQIKEAVRAD 17975
Query: 969 PGVTYYFKVFAVSHGRESKPLTAQQTTKLDAP---TNLQFVNETDSTVLVRWTPPRAQIT 1025
G + H + S + LD P NL+ N T + W P
Sbjct: 17976 HGKYIISAKNSSGHAQGSAIVNV-----LDRPGPCQNLKVTNVTKENCTISWENPLDN-G 18029
Query: 1026 GYRLTVGLTRRGQPRQYN---VGPSVSKYPLR-NLQPASEYTVSLVAIKGNQESPKATGV 1081
G +T + +P Q V V+K ++ NL +EY + A GV
Sbjct: 18030 GSEITNFIVEYRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCA-------ENKVGV 18082
Query: 1082 FTTLQPGSSI----------PPYNTEVTE---TTIVITWTP------APRIGFKLG--VR 1120
T++ + I P N + + T + + W +P + + + ++
Sbjct: 18083 GPTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLK 18142
Query: 1121 PSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP---LSPP 1177
S E + + +V Y + +Q +G E D +VV P
Sbjct: 18143 GSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPV 18202
Query: 1178 TNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNL 1237
+L L +GVLTV G I G +G EV T
Sbjct: 18203 LDLKL-----SGVLTVK---------AGDTIRLEA--GVRGKPFPEVAWTKDKDATDLTR 18246
Query: 1238 SPGLEYNVSVYTVKDDKESVPISD---------------------TIIPAVPPPTDLRFT 1276
SP ++ + + K SD ++ P +L+
Sbjct: 18247 SPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIV 18306
Query: 1277 NIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTE 1333
++ D V W PP ++ N+++ K + S + +T L+ G E
Sbjct: 18307 DVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMV-WSTYSATVLTPGTTVTRLIEGNE 18365
Query: 1334 YVVSVSSVYEQHESTPLRGRQ---KTGLDSPTGIDFSDITANS---FTVHWIAPR----A 1383
Y+ V + + P + KT D P D ++T S TV W P
Sbjct: 18366 YIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGK 18425
Query: 1384 TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN-------GREE 1436
+ITGY + +H + ++ + + NL P EY + A N
Sbjct: 18426 SITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPS 18485
Query: 1437 SPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP-----AVTVRYYRITYGETGGNSPV 1491
P++ P + VV T S+ + W P A + Y + SP
Sbjct: 18486 RPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPD 18545
Query: 1492 QEFTVPGS-----KSTATISGLKPGVDYTITVYAVTGRG-DSPASSKPISINYRTEIDKP 1545
+ + + + T++ L +Y V A G PA K E KP
Sbjct: 18546 EGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELK--------EAIKP 18597
Query: 1546 SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKT-KTAGPDQTEMTIE-GLQ 1603
++ D S++ L R+ + P P T + G D + L
Sbjct: 18598 KEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLV 18657
Query: 1604 PTVEYVV------------SVYAQNPSGESQPLVQTAVTNIDRP-KGLAFTDVDVDSIKI 1650
T+ ++V S+ NP+GE V V + P L +DV S +
Sbjct: 18658 DTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHV 18717
Query: 1651 AWESPQG----QVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH 1706
+W P+ QV+ Y V + P+ ++ + + L PG+EY V A++
Sbjct: 18718 SWAPPENDGGSQVTHYIVEKREADRKTWSTV-TPEVKKTSFHVTNLVPGNEYYFRVTAVN 18776
Query: 1707 D-------DMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP--------NVQLTG 1751
+ D+ L + P L+ T++T S + W PP + +T
Sbjct: 18777 EYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITS 18836
Query: 1752 YRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP--AQGVVT 1809
YR P ++ E ++ D S +VV+GL KY+ V A S P A+GV
Sbjct: 18837 YREEEQPADR---WTEYSVVKDLS-LVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYE 18892
Query: 1810 TLENVSPPRRARVTDAT---------------ETTITISWRT-KTETITGFQVDAVPANG 1853
E + PP+ T + T W+ + E +T + A+
Sbjct: 18893 AKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADS 18952
Query: 1854 QTP--IQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRF 1911
+ I+ + D Y++T D + VV+DA P ++
Sbjct: 18953 SSILIIKDVTRKDSGYYSLTAENSSG---------TDTQKIKVVVMDAPGPPQPPFDISD 19003
Query: 1912 LATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGT 1967
+ SL SW P + IT YI++ + S V T + L PG
Sbjct: 19004 IDADACSL--SWHIPLEDGGSNITNYIVE-KCDVSRGDWVTALASVTKTSCRVGKLIPGQ 19060
Query: 1968 EYTIYVIALKNNQKSEPLIGRKKTDELP 1995
EY V A SEPL K + P
Sbjct: 19061 EYIFRVRAENRFGISEPLTSPKMVAQFP 19088
Score = 90.9 bits (224), Expect = 1e-17
Identities = 273/1318 (20%), Positives = 459/1318 (34%), Gaps = 189/1318 (14%)
Query: 771 TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP---DPTVDQVDDTSI 827
++TS + DL + V +E G +T A + P D ++ TS+
Sbjct: 27420 SSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSV 27479
Query: 828 VVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAV 883
++ W++P + IT Y + E + + + +T + +S L+ ++A
Sbjct: 27480 ILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTCE-IEVSQLKEQSVLEFRVFAK 27538
Query: 884 EENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIP 943
E S PV I T + + +P ++ ++ +VT+ Y+ P
Sbjct: 27539 NEKGLSDPVTIGPITV----KELIITP-EVDLSDIPGAQVTVRIGHNVHLELPYKGKPKP 27593
Query: 944 VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN- 1002
+ G LP+ + F + +T K HG + + ++ P
Sbjct: 27594 SISWLKDG--LPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITV 27651
Query: 1003 ------------LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP 1046
++F +V++ W P +IT Y + T + +
Sbjct: 27652 ITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSV 27711
Query: 1047 SVSKYPLRNLQPASEYTVSLVAI-KGNQESPKATGVFTTLQ----PGSSIPPYNTEVTET 1101
+ + + + NL +EY + A + P + + PG P VT
Sbjct: 27712 ARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSD 27771
Query: 1102 TIVITWTP------APRIGFKLGVRPSQGGEAPREVTSD-SG-SIVVSGLTPGVEYVYTI 1153
+ +TW + GF + + + TS SG +GL G++Y + +
Sbjct: 27772 GMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRV 27831
Query: 1154 QVLRDG---QERDAPIVNKVVTPLSPP-TNLHLEANPDTGVLTVSWE---RSTTPDITGY 1206
D V+P+ PP T +++ +T +T+ W R I GY
Sbjct: 27832 YAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRET--ITLKWNPPLRDGGSKIVGY 27889
Query: 1207 RITTTPTNGQQGNSL-EEVVHADQSSC--TFDNLSPGLEYNV------SVYTVKDDKESV 1257
I +QGN D S C T LSPG Y +V T+ +S
Sbjct: 27890 SIEK-----RQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSS 27944
Query: 1258 PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAEL 1314
I T VPP GP+ LV+ PV +D E+
Sbjct: 27945 GIIMTRDENVPP-----IVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEI 27999
Query: 1315 SISPSDNAVVLTNLLPGTEYVV--------SVSSVYEQHESTPLRGRQKTGLDSPTG--- 1363
+ + +T++L T V V +V ++ S + K + G
Sbjct: 28000 EKRMN---MEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVV 28056
Query: 1364 --IDFSDITANSFTVHWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLT 1416
I F++IT T+ W AP A IT Y I + + ED+ S T
Sbjct: 28057 GPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC--EAQSYTAI 28114
Query: 1417 NLTPGTEYVVSIVALN----GR--EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
L G EY + A+N GR + P++ Q TV D P E T S+ ++W
Sbjct: 28115 KLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWAR 28174
Query: 1471 PAVTVRYYRITYGETGGNSPVQEFTV-----------------PGSKSTATISGLKPGVD 1513
P E+ G S +Q++ + P S++ ++GL G +
Sbjct: 28175 P------------ESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNE 28222
Query: 1514 YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ---MQVTDVQDNSISVKW----LPSS 1566
Y V A G PAS I R ++ P ++VTD ++S++W
Sbjct: 28223 YEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGG 28282
Query: 1567 SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ 1626
+ GY + + K +T T+ LQ EY V A N +G+
Sbjct: 28283 MEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEV 28342
Query: 1627 TA-VTNIDRPKGLAFTDVDVDS-IKIAWESPQGQVSRYRVTY----------SSPEDGIH 1674
T + +DR L ++D+D+ K G R + Y S P+ +
Sbjct: 28343 TGTIKAVDR---LTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLS 28399
Query: 1675 ---ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFT 1731
++ T E +YT++V + T P P + F
Sbjct: 28400 LRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP-PGPITFK 28458
Query: 1732 QVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE----INLAPDSSSVVVSGLMVATK 1787
VT S + W P + G R+ EK + I+ V+ L
Sbjct: 28459 DVTRGSATLMWDAPLLD-GGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVP 28517
Query: 1788 YEVSVYALKDTLTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISW----RTKTETI 1841
Y V A+ + P + + E +PPRR V D ++++ ++W I
Sbjct: 28518 YYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRI 28577
Query: 1842 TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1901
TG+ ++ ++ + ++T+ L T+Y+ + ND S P +S
Sbjct: 28578 TGYLLEMRQKGSDFWVEAGHTKQL-TFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSV 28636
Query: 1902 AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP---RPRPGVT 1956
I P P + L IT +I K GSP VP RP P VT
Sbjct: 28637 IIKEPQ------IEPTADLTG-------ITNQLITC-KAGSPFTIDVPISGRPAPKVT 28680
Score = 90.1 bits (222), Expect = 2e-17
Identities = 343/1758 (19%), Positives = 611/1758 (34%), Gaps = 294/1758 (16%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W P S I YI+ R + + W S + L G Y +++++
Sbjct: 22656 LAWKPPLQDGGSDIINYIVERRETSRLV-WTVVDANVQTLSCKVTKLLEGNEYTFRIMAV 22714
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVS-A 743
+YG E P+ S V + P + VT +T S +V W A
Sbjct: 22715 NKYGVGE-------------PLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPA 22761
Query: 744 SD---TVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKY-----IVNVYQISE 795
SD + G+ +E E + + + L+ Y N +SE
Sbjct: 22762 SDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSE 22821
Query: 796 DGEQSLILSTSQTTAPDAPPD-PTVDQVDDTSIVVRWSRP----QAPITGYRIVYSPSVE 850
S PP+ P V + +S+ + WS+P I GY +
Sbjct: 22822 PSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSV 22881
Query: 851 GSSTELNLPETAN--SVTLSDLQPGVQYNITIYAVE-----ENQESTPVVIQQETTGTPR 903
G T P N ++ + L +YN I A+ E+ + +I +E P
Sbjct: 22882 GEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPD 22941
Query: 904 SDTVPSPRDLQFVEVTDVK--------VTIMWTP-PE---SAVTGYRVDVIPVNLPGEHG 951
D DL+ ++ +++ V I P PE V G D +++
Sbjct: 22942 IDL-----DLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFT 22996
Query: 952 QRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDS 1011
+ + N + Y S G +S +T + P NL+ T
Sbjct: 22997 SLVLDNVNRYDSGK--------YTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKD 23048
Query: 1012 TVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLV 1067
+V + W PP ++I Y + R + + + LQ Y +
Sbjct: 23049 SVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVT 23108
Query: 1068 A-----IKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIG------FK 1116
A I ++ V QP I +VT ++ ++WT G +
Sbjct: 23109 AENEYGIGLPAQTADPIKVAEVPQPPGKITV--DDVTRNSVSLSWTKPEHDGGSKIIQYI 23166
Query: 1117 LGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERD-----APIVNK-- 1169
+ ++ + S V++ LT G EY++ + + + D PIV K
Sbjct: 23167 VEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDL 23226
Query: 1170 VVTPLSPP--TNLHLEANPDTGVL---------TVSWERSTTPDITGYRITTTPTNGQQG 1218
V+ P P ++ ++ D + T++W + P RI T +
Sbjct: 23227 VIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTT 23286
Query: 1219 NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNI 1278
S++E H D G +Y ++V V K + T+ PP ++F ++
Sbjct: 23287 LSIKET-HKDD----------GGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDV 23335
Query: 1279 GPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEE-DVAELSISPSDNAVVLTNLLPGTEY 1334
+++ ++W PP +TN++V+ DV +++ + + +T L GTEY
Sbjct: 23336 SAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVART--TLKVTKLKTGTEY 23393
Query: 1335 VVSV--SSVYEQH---ESTPLRGRQKTGLDSPTGIDFSD-ITANSFTVHWIAP----RAT 1384
+ + Y Q ES P+ + P G F+ I+ +S + W P +
Sbjct: 23394 QFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSP 23453
Query: 1385 ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQ 1444
+ GY + + + ++ NL G EY + A E+ + +G+
Sbjct: 23454 VIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYA-----ENIVGVGKA 23508
Query: 1445 STVSD--VPRDLEVVAATPTSLLISWDAPAVTVRYYRITY--GETGGNSPVQEFTVPGSK 1500
S S+ V RD TP +++ + +T+++ + Y G V++ +P +
Sbjct: 23509 SKNSECYVARDPCDPPGTPEPIMVKRNE--ITLQWTKPVYDGGSMITGYIVEKRDLPDGR 23566
Query: 1501 -----------STATISGLKPGVDYTITVYAVTGRGDSPASSKPIS----INYRTEIDKP 1545
+ T+SGL Y V A G A SKP I + E++ P
Sbjct: 23567 WMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAG---AISKPSDSTGPITAKDEVELP 23623
Query: 1546 SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPT 1605
+D + + +R+ P PT G + E +
Sbjct: 23624 RISMDPKFRDTIVV-------NAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKN 23676
Query: 1606 VEYVVSVY---------------AQNPSGESQPLVQTAVTNIDRPKG----LAFTDVDVD 1646
++ + A N +G V V +DRP + T V +
Sbjct: 23677 TDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKV--LDRPGPPEGPVQVTGVTSE 23734
Query: 1647 SIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSV 1702
+ W P +S Y V + A + ++ ++ L G+EY +
Sbjct: 23735 KCSLTWSPPLQDGGSDISHY-VVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRI 23793
Query: 1703 VALH-----DDMESQPLIGTQSTAIPAPT-DLKFTQVTPTSLSAQWTPPNV----QLTGY 1752
+A++ + +ES P++ +P P L+ T + S++ W P+ ++ GY
Sbjct: 23794 MAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGY 23853
Query: 1753 RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVV---- 1808
V + +K + V+GL +YE V A P+ V
Sbjct: 23854 IVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKA 23913
Query: 1809 -TTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKP 1863
+ PP A + D T+ +IT++W I G+ V+ A+ + + + P
Sbjct: 23914 CDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEE--WQIVTP 23971
Query: 1864 D----VRSYTITGLQPGTDYKIYLYTLN----DNARSSPVVIDASTAIDAPSNLRFLATT 1915
V + I+ L +YKI + LN A S P + ++AP L +
Sbjct: 23972 QTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAP-ELDLDSEL 24030
Query: 1916 PNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP---RPRPGVTEATITG-------LEP 1965
++V + G R +P RP P +T + G +E
Sbjct: 24031 RKGIVV-----------------RAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEK 24073
Query: 1966 GTEYT-------------IYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILD 2012
G YT Y++ L+N+ S+ K + P P NL E+
Sbjct: 24074 GVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPG----PPQNLAVKEVRK 24129
Query: 2013 VPSTVQKTPFVTHPGYDTGNGI----------------QLPGTSGQQPSVGQQMIF---- 2052
+ + P + G N + + TS + ++ + I+
Sbjct: 24130 DSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRV 24189
Query: 2053 -EEHGFRRTTPPTTATPIRHRPRPYPP-NVGQEALSQTTIS--W-APFQDTSE----YII 2103
E+ F P T ++ P PP V +SQT+ S W P D Y++
Sbjct: 24190 MAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVV 24249
Query: 2104 SCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSV 2163
P GT E +A +TGL+ G Y V+A ++ + R V+ V
Sbjct: 24250 EMQPKGT--EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPR--VLGVPVIA 24305
Query: 2164 NEGLNQPTDDSCFDPYTV 2181
+ QP+ F+ Y++
Sbjct: 24306 KDLTIQPSLKLPFNTYSI 24323
Score = 89.7 bits (221), Expect = 3e-17
Identities = 260/1286 (20%), Positives = 475/1286 (36%), Gaps = 231/1286 (17%)
Query: 780 LLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPIT 839
++P ++Y++ V ++ G + A D PT+D IV+ + P+
Sbjct: 14350 VVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVP 14409
Query: 840 GYRIVYSPSV----EGSSTELNLPETANSVTLS---DLQPGVQYNITIYAV--EENQEST 890
+R V P+V +G + + T + +S ++ V+ + IY + E S
Sbjct: 14410 -FRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSA 14468
Query: 891 PVVIQQETTGTPRSDTVPSP-RDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGE 949
I + G +P P +D++ ++T + W PPE G + V E
Sbjct: 14469 TASINVKVIG------LPGPCKDIKASDITKSSCKLTWEPPE--FDGGTPILHYVLERRE 14520
Query: 950 HGQR--LPI--SRNTFA-EVTGLSPGVTYYFKVFAVSH--GRE----SKPLTAQQTTKL- 997
G+R +P+ N + V L P Y+F+V AV+ G E P+ AQ +
Sbjct: 14521 AGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPP 14580
Query: 998 DAPTNLQFVNETDSTVLVRWTPPR----AQITGY---RLTVGLTRRGQPRQYNVGPSVSK 1050
D P +++ N T + + W PP ++I GY ++ G R + ++ V +
Sbjct: 14581 DPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLV--PILT 14638
Query: 1051 YPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
Y + L+ EY + A A G+ +P + PP T + A
Sbjct: 14639 YTAKGLEEGKEYQFRVRA-------ENAAGIS---EPSRATPP--------TKAVDPIDA 14680
Query: 1111 PRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVL--RDGQERDAPIVN 1168
P++ + + +G E + S SGS P + ++ V+ + ++R AP+V
Sbjct: 14681 PKVILRTSLEVKRGDEIALDA-SISGSPY-----PTITWIKDENVIVPEEIKKRAAPLVR 14734
Query: 1169 KVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHAD 1228
+ + L P T L++ N ++G S V
Sbjct: 14735 RRKGEVQEEEPFVL---PLTQRLSID-------------------NSKKGESQLRVR--- 14769
Query: 1229 QSSCTFDNLSPGLEYNVSVYTVKDDK--ESVPISDTIIPAVPPPTDLRFTNIGPDTMRVT 1286
D+L P ++ + + V++D P + +++ PP + F +I ++
Sbjct: 14770 ------DSLRP--DHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCK 14821
Query: 1287 WAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE 1346
W PP D + ++ Y+ K ++ P +V+T+ L +Y SV+ + E E
Sbjct: 14822 WEPPLD-DGGSEIINYTLEKKDKT------KPDSEWIVVTSTLRHCKY--SVTKLIEGKE 14872
Query: 1347 ------------------STPLRGRQKTGL-DSPTGIDFSDITANSFTVHWIAPR---AT 1384
S PL + G D+P D+T+NS V W P+ +
Sbjct: 14873 YLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSP 14932
Query: 1385 ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLL 1440
I GY + + + R ++ + + L G YV + A N G+ P
Sbjct: 14933 ILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPP-- 14990
Query: 1441 IGQQSTVSD--------VPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGN 1488
T D +PR V + T++ + W+ PA + Y + G N
Sbjct: 14991 -SDPKTAHDPISPPGPPIPR---VTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTN 15046
Query: 1489 SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEIDKPSQ 1547
+ T+ ++ G DY + V AV G+ P ++P+++ E +P
Sbjct: 15047 EWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQPVTV---AEPQEPPA 15103
Query: 1548 MQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTK--TKTAGP-DQTEMTIEGLQP 1604
+++ +SVK R+ P PTK TK G D+ + I+ +
Sbjct: 15104 VEL------DVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGT 15157
Query: 1605 TVEYVVS-----------VYAQNPSGESQPLVQTAVTNIDRP-KGLAFTDVDVDSIKIAW 1652
E ++ + A N G + V ++ P L + + W
Sbjct: 15158 KSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNW 15217
Query: 1653 ESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH-- 1706
P+ +++ + + + +H + E ++ GL G EY V+A +
Sbjct: 15218 SDPEDDGGSEITGFIIERKDAK--MHTWRQPIETERSKCDITGLLEGQEYKFRVIAKNKF 15275
Query: 1707 ---DDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTP 1758
+E P++ P +P L +T+ T ++++ W P + GY +
Sbjct: 15276 GCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRR 15335
Query: 1759 KEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPA--QGVVTTLENVSP 1816
+K + ++S +V L YE V A+ + S P+ VV + V P
Sbjct: 15336 HDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPP 15395
Query: 1817 PRRARVTDATETTIT-------------------ISWRTKTETITGFQVDAVPANGQTPI 1857
+ R++ +T I W +K ET+ DA+ +
Sbjct: 15396 TIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEW-SKNETVIEKPTDALQITKEEVS 15454
Query: 1858 QRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI-DAPSNLRFLATT- 1915
+ K ++ GT YT+ + R V + + D PS R LA T
Sbjct: 15455 RSEAKTELSIPKAVREDKGT------YTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTD 15508
Query: 1916 --PNSLLVSWQPP----RARITGYII 1935
S ++W P + IT Y+I
Sbjct: 15509 IKAESCYLTWDAPLDNGGSEITHYVI 15534
Score = 87.4 bits (215), Expect = 1e-16
Identities = 347/1579 (21%), Positives = 545/1579 (34%), Gaps = 257/1579 (16%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W +P+ S I+ Y++ R + W T + T++GL G Y ++ +
Sbjct: 16635 LTWFSPEDDGGSPITNYVIEKRESDRRA-WTPVTYTVTRQNATVQGLIQGKAYFFRIAAE 16693
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
G F TS + + T P P V E+T ++ ++W
Sbjct: 16694 NSIGMGP-----FVETSEALVIREPI----TVPERP---EDLEVKEVTKNTVTLTWNPPK 16741
Query: 745 DTVSGFRVEYELSEE--GDEPQYLDLPSTATS--VNIPDLLPGRKYIVNVYQISEDGEQS 800
+ Y L G E + S + L G Y V ++ G+
Sbjct: 16742 YDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGK 16801
Query: 801 LILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPE 860
T T D PT+ + +R A Y P V E ++ E
Sbjct: 16802 PSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 16861
Query: 861 TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET---TGTPRSDTVPSPRD----L 913
+ T P I A + VV++ T G + + V P +
Sbjct: 16862 --DDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPV 16919
Query: 914 QFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI---SRNTFAEVTG 966
F EVT + I W PP S +T Y ++ V +P+ S T +V+
Sbjct: 16920 SFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVG----KDVWMPVTSASAKTTCKVSK 16975
Query: 967 LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD------APTNLQFVNETDSTVLVRWTPP 1020
L G Y F++ A + S PL + D AP T + LV W P
Sbjct: 16976 LLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP 17035
Query: 1021 R---AQITGYRLTVGLTRRGQPRQYNVGP--SVSKYPLRNLQPASEYTVSLVA---IKGN 1072
IT Y L T + + P +K+ + +L +Y + A I
Sbjct: 17036 HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIG 17095
Query: 1073 QESPKATGVFTTLQPGSSIPPYNTEVTETT---IVITWTPAPR-------IGFKLGVRPS 1122
SP + VF PP N E +TT + +TW P PR +G+ + +
Sbjct: 17096 DPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQP-PRHDGGSKILGYIVEYQ-K 17153
Query: 1123 QGGEAPREVTSDSGSIV-----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP---L 1174
G E R S V+GL G Y + + + E D V + V L
Sbjct: 17154 VGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRL 17213
Query: 1175 SPPTNLHLEANP---------DTGVLT----------VSWERSTTPDITGYRITTTPTNG 1215
PP L L+AN DT L+ V+W++ T RI TP
Sbjct: 17214 EPP-ELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS 17272
Query: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRF 1275
+ + H D + +P VSV + DK PP DL
Sbjct: 17273 KL--EIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG------------PPRDLEV 17318
Query: 1276 TNIGPDTMRVTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332
+ I D+ +TW P +TN++V V + + + LS + + +L G
Sbjct: 17319 SEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ-WSPLSATSKKKSHFAKHLNEGN 17377
Query: 1333 EYVVSVSSVYEQHESTPLRGRQKT--GLDS------PTGIDFSDITANSFTVHWIAPR-- 1382
+Y+ V++ Q+ P K LD P + D+ ++ W P
Sbjct: 17378 QYLFRVAAE-NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRD 17436
Query: 1383 --ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREE 1436
+ ITGY + + E + V + +T L G Y + A N G +
Sbjct: 17437 GGSPITGYLVEYQEEGTQDWIKFKTVTNLE--CVVTGLQQGKTYRFRVKAENIVGLGLPD 17494
Query: 1437 SPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTV 1496
+ + I Q + VP +E+ L++ TVR+ I G P ++T
Sbjct: 17495 TTIPIECQEKL--VPPSVELDVKLIEGLVVK---AGTTVRFPAIIRGVP---VPTAKWTT 17546
Query: 1497 PGSK---------------STATISGL--KPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
GS+ S TI + +Y ITV + A SK ++++
Sbjct: 17547 DGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV-------SNAAGSKTVAVHL- 17598
Query: 1540 TEIDKPSQ----MQVTDVQDNSISVKWLP----SSSPVTGYRVTT--TPKNGPGPTKTKT 1589
T +D P + + DV +++ W P SPV Y V T K+ G +
Sbjct: 17599 TVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVV---S 17655
Query: 1590 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR------PKGLAFTDV 1643
+G +T++ I LQ EYV V A+N G PL T + P TD+
Sbjct: 17656 SGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDI 17715
Query: 1644 DVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQ----GLRPGSEYT 1699
++ ++W P+ Y + + + + A+L+ GL G+ Y
Sbjct: 17716 TENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVN-KTPIADLKFRVTGLYEGNTYE 17774
Query: 1700 VSVVALH------DDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPP----NVQ 1748
V A + S P+ + P P + K + + WT P
Sbjct: 17775 FRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSP 17834
Query: 1749 LTGYRVRVTPKEKTGPMKEINLAP--DSSSVVVSGLMVATKYEVSVYALKDTLTSRP--- 1803
+ GY V K T IN + V GL+ +Y + A P
Sbjct: 17835 ILGYVVE-CQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPREL 17893
Query: 1804 AQGVVTTLENVSPPR-------RARVTDATETTITISWRTK-------TETITG------ 1843
A+ V+ + + PP R +T TI I R K T T G
Sbjct: 17894 AESVIAK-DILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVRE 17952
Query: 1844 FQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI 1903
+VD + + +Q IK VR+ Y I + +A+ S +V +
Sbjct: 17953 KRVDLIQDLPRVELQ--IKEAVRA-------DHGKYIISAKNSSGHAQGSAIV----NVL 17999
Query: 1904 DAP---SNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVT 1956
D P NL+ T + +SW+ P + IT +I++Y KP +V VT
Sbjct: 18000 DRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIV---ASDVT 18056
Query: 1957 EATI-TGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPS 2015
+ I L EY V A +N P I K P L P PE L +
Sbjct: 18057 KRLIKANLLANNEYYFRVCA-ENKVGVGPTIETK----TPILAINPIDRPGEPENLHIAD 18111
Query: 2016 TVQKTPFV--THPGYDTGN 2032
+ ++ P YD G+
Sbjct: 18112 KGKTFVYLKWRRPDYDGGS 18130
Score = 85.5 bits (210), Expect = 6e-16
Identities = 330/1597 (20%), Positives = 570/1597 (35%), Gaps = 278/1597 (17%)
Query: 737 VVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQ 792
+++W D ++GF +E + ++ Q ++ + + +I LL G++Y V
Sbjct: 15214 LLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIE--TERSKCDITGLLEGQEYKFRVIA 15271
Query: 793 ISEDG-----EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQA----PITGYRI 843
++ G E IL+ P +P T + ++I + W P++ PI GY I
Sbjct: 15272 KNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYII 15331
Query: 844 VY----SPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTP-----VVI 894
P E + L P T S + +L Y + AV E ES P VVI
Sbjct: 15332 EKRRHDKPDFERVNKRL-CPTT--SFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVI 15388
Query: 895 QQETTG-------TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLP 947
Q + + R DT+ ++ E + + P VI
Sbjct: 15389 QDDEVPPTIKLRLSVRGDTIK----VKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTD 15444
Query: 948 GEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH----GRESKPLTAQQTTKLDAPTNL 1003
+ +SR+ + V + V+ G + + + + P NL
Sbjct: 15445 ALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNL 15504
Query: 1004 QFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV--SKYPLRNLQ 1057
+ + + W P ++IT Y + R + V + +Y + L
Sbjct: 15505 AVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLI 15564
Query: 1058 PASEYTVSLVAIKGNQESPKATGVFTTLQ-----PGSSIPPYNTEVTETTIVITWTP--- 1109
P +Y + A+ S + +Q PG P T+ +++++WTP
Sbjct: 15565 PNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLD 15624
Query: 1110 ---APRIGFKLGVRP------SQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVLR-- 1157
+P G+ L R S+ AP G V L GV+Y + +
Sbjct: 15625 NGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAA 15684
Query: 1158 ----DGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE---RSTTPDITGYRITT 1210
+ D + + P PP+ ++ + + ++ W+ + I GY +
Sbjct: 15685 GIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSI-SLGWKPPAKDGGSPIKGYIVEM 15743
Query: 1211 TP---TNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAV 1267
T+ ++ N ++++ + C NL +Y V V + ES P SDT
Sbjct: 15744 QEEGTTDWKRVNEPDKLITTCE--CVVPNLKELRKYRFRVKAVNEAGESEP-SDTT--GE 15798
Query: 1268 PPPTDLR-----FTNIGPDTMRVTWA-------------PPPS----IDLTNFLVRYSPV 1305
P TD++ F +IG V A P P D V
Sbjct: 15799 IPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGV 15858
Query: 1306 KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP-LRGRQKTGLDSPTGI 1364
+ + A+L + + + +++ S+++ + + T R + P +
Sbjct: 15859 HDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDL 15918
Query: 1365 DFSDITANSFTVHWIAPRAT----ITGYRIRHHPEHFSGRPREDRVPH-SRNSITLTNLT 1419
SDIT S + W P I GY I G+ P + + +L
Sbjct: 15919 KVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRT--IDGKAWTKVNPDCGSTTFVVPDLL 15976
Query: 1420 PGTEYVVSIVALNGREESPLLIGQQSTVS-------DVPRDLEVVAATPTSLLISWDAPA 1472
+Y + A N P + Q T + D P L++ T ++ +SW P
Sbjct: 15977 SEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPP- 16035
Query: 1473 VTVRYYRITYGETGGNSPVQEFTVP-------GSKSTA--------------TISGLKPG 1511
+ G SPV + V G+K A T+ L G
Sbjct: 16036 -----------KNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEG 16084
Query: 1512 VDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTG 1571
+Y V AV G S S+ P Q D+ SI +K T
Sbjct: 16085 GEYEFRVKAVNAAGVSKPSATV----------GPCDCQRPDMPP-SIDLKEFMEVEEGTN 16133
Query: 1572 YRVTTTPKNGPGPT----KTKTAGPDQTEMTIEGLQPTVEYV----VSVYAQNPSGESQP 1623
+ K P PT K PD E + V V Q+ ++
Sbjct: 16134 VNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGL 16193
Query: 1624 LVQTAVTNIDR---------------PKG-LAFTDVDVDSIKIAWESPQ----GQVSRYR 1663
TAV N+ P G + F V D + ++W P+ +++ Y
Sbjct: 16194 YTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYV 16253
Query: 1664 VTY--SSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVA-----LHDDMESQPLIG 1716
+ ++ + +H + + +E T + L G EY ++A + + ++S+P
Sbjct: 16254 IEKREANRKTWVHV---SSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETA 16310
Query: 1717 TQSTAIP-APTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPM-KEINL 1770
++P AP + VT S++ W P +TGY + + K+ T K +N
Sbjct: 16311 RNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEM--KDTTSKRWKRVNR 16368
Query: 1771 APDSS-----SVVVSGLMVATKYEVSVYALKD------TLTSRPAQGVVTTLENVSPPRR 1819
P + S V+GL+ + Y+ VYA+ +L S PA T + ++PP
Sbjct: 16369 DPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPA----TARDPIAPPGP 16424
Query: 1820 A--RVTDATETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRS--YTIT 1871
+VTD T+++ + W + +TG+ V+ G+ ++ +VR +T
Sbjct: 16425 PFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVE-YKEEGKEEWEKGKDKEVRGTKLVVT 16483
Query: 1872 GLQPGTDYKIYLYTLNDNARSSPV----VIDASTAIDAPSNLRFLATTPNSLLVSWQPPR 1927
GL+ G YK + +N P VI+ + +P +L+ A+ + ++V
Sbjct: 16484 GLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSP-DLQLDASVRDRIVVH-AGGV 16541
Query: 1928 ARITGYIIKYEKPGSPPREVV--PRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP- 1984
RI Y+ G PP V R EATI T + +KN Q+S
Sbjct: 16542 IRIIAYV-----SGKPPPTVTWNMNERTLPQEATIE-----TTAISSSMVIKNCQRSHQG 16591
Query: 1985 ---LIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQL----P 2037
L+ + + E + + + ++LDVP V TPF+ H T +L P
Sbjct: 16592 VYSLLAKNEAGERKKTIIV--------DVLDVPGPVG-TPFLAHNL--TNESCKLTWFSP 16640
Query: 2038 GTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQ----EALSQTTISWA 2093
G P + +I + RR P T T R G+ ++ +I
Sbjct: 16641 EDDGGSP-ITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMG 16699
Query: 2094 PFQDTSEYIISCHPVGTDEEPLQFRVPG-TSTSATLT 2129
PF +TSE ++ P+ E P V T + TLT
Sbjct: 16700 PFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLT 16736
Score = 85.5 bits (210), Expect = 6e-16
Identities = 343/1679 (20%), Positives = 586/1679 (34%), Gaps = 264/1679 (15%)
Query: 611 PVEVFITETPSQPNSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNS-Y 666
P V +T+T S ++W+ P I YI+ K +G W + + + Y
Sbjct: 28257 PTVVKVTDTSKTTVS--LEWSKPVFDGGMEIIGYIIEMC-KADLGDWHKVNAEACVKTRY 28313
Query: 667 TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
T+ L+ G Y+ ++ +I G + S T V T P + A +
Sbjct: 28314 TVTDLQAGEEYKFRVSAINGAGKGD---------SCEVTGTIKAVDRLTAPELDIDANFK 28364
Query: 727 SVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLP 782
+ A + + +++ + T + + LS D D ST T N
Sbjct: 28365 QTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADI-HTTDSFSTLTVENCNRNDA 28423
Query: 783 GRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----API 838
G KY + V S G +S+ + P P T V S + W P A I
Sbjct: 28424 G-KYTLTVENNS--GSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARI 28480
Query: 839 TGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898
Y + + S ++ T ++DL GV Y + AV E P + +
Sbjct: 28481 HHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPI 28540
Query: 899 TGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVN----LPGEH 950
T + PR L V+ + + W P+ S +TGY +++ + H
Sbjct: 28541 VATEQP---APPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGH 28597
Query: 951 GQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETD 1010
++L + E T Y F+V A + S+P A + + P
Sbjct: 28598 TKQLTFTVERLVEKT------EYEFRVKAKNDAGYSEPREAFSSVIIKEPQ--------- 28642
Query: 1011 STVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNV------GPSVSKYPLRNLQPASEYTV 1064
P A +TG + + G P +V P V+ + L ++ V
Sbjct: 28643 -------IEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVT-WKLEEMRLKETDRV 28694
Query: 1065 SLVAIKGN-----QESPKATG--VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIG--- 1114
S+ K ++S + F TL+ + + ++ T+V+ P P G
Sbjct: 28695 SITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSV-----TVVVIGRPGPVTGPIE 28749
Query: 1115 ----------FKLGVRPSQGGEAPREVTS------DSGS--------------IVVSGLT 1144
G P GG E+T+ +SG+ I V+ LT
Sbjct: 28750 VSSVSAESCVLSWG-EPKDGGGT--EITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLT 28806
Query: 1145 PGVEYVYTIQVL-RDGQER---DAPIV--NKVVTPLSP--PTNLHLEANPDTGVLTVSWE 1196
+EY + + R G + API+ + V P +P P H+ AN +++ WE
Sbjct: 28807 KYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSAN----AMSIRWE 28862
Query: 1197 RSTTPDITGYRITTTPTNGQQGNSL----EEVVHADQSSCTFDNLSPGLEYNVSVYTV-- 1250
G +I ++ N++ E V + + L GLEY Y +
Sbjct: 28863 EPYHDG--GSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNA 28920
Query: 1251 ----KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYS 1303
K + S PI V P T++ T+ + W+ P + +++
Sbjct: 28921 AGVSKASEASRPIMAQ--NPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERK 28978
Query: 1304 PVKNEEDVAELSIS---PSDNAVVLTNLLPGTEYVVSVSS------VYEQHEST-PLRGR 1353
PV D L + SDN +T L G Y V + + + EST P+ R
Sbjct: 28979 PVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCR 29038
Query: 1354 Q-----KTGLDSPTGIDFSDITANSFTVHWIA----PRATITGYRIRHHPEHFSGRPRED 1404
K LD+ D I A S V A P I + + +
Sbjct: 29039 DEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY 29098
Query: 1405 RVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRD---LEVVAATP 1461
+ I + + +Y +++ +G + +++ V D P L V T
Sbjct: 29099 TGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMV----KVLDSPGPCGKLTVSRVTQ 29154
Query: 1462 TSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT--ISGLKPGVDYT 1515
++W P + +Y + ET S + V G T + ++ L +Y
Sbjct: 29155 EKCTLAWSLPQEDGGAEITHYIVERRET---SRLNWVIVEGECPTLSYVVTRLIKNNEYI 29211
Query: 1516 ITVYAVTGRGDS-PASSKPISINYRTEIDKPSQM-QVTDVQDNSISVKWLPSSSP----V 1569
V AV G P S+PI I P + + I ++W S +
Sbjct: 29212 FRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEI 29271
Query: 1570 TGYRVTTTPKNGPGPTKT-KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628
+ Y V K T+ K T + + L +Y V A N +G S+P +
Sbjct: 29272 SNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASN 29331
Query: 1629 VTNIDRPK-------GLAFTDVDVDSIKIAWESPQGQVSRYRVTY-----SSPEDGIHEL 1676
+ P D SI +AW P V Y D + +
Sbjct: 29332 FISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRV 29391
Query: 1677 FPAPDGEEDTAELQGLRPGSEYTVSVVALH---------DDMESQPLIGTQSTAIPAPTD 1727
+ L+ G +Y+ V A++ E +P+ + + D
Sbjct: 29392 HTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADD 29451
Query: 1728 LKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTG---PMKEINLAPDSSSVVVSGLMV 1784
LK T S + V ++G V K G + I +S S+++ +
Sbjct: 29452 LKKTVTIRAGASLRLM---VSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKV- 29507
Query: 1785 ATKYEVSVYALKDTLTS--RPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT---- 1838
+Y+ Y ++ S + A +V + P +V + + ++TI+W T
Sbjct: 29508 -NRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGG 29566
Query: 1839 ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIY-----LYTLNDNARSS 1893
+ + V+ A + T K Y I+GL GT Y +Y + + +S
Sbjct: 29567 APVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETS 29626
Query: 1894 PVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVP 1949
V+ + + P+ L + T +++ ++W+ P +R+TGY+++ K G+ V
Sbjct: 29627 DAVLVSEVPL-VPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVV 29685
Query: 1950 RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPE 2009
+P V E T+T L G +Y + A SEP E VT+ +L
Sbjct: 29686 TLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEP-------RETVTAVTV--QDLRVLP 29736
Query: 2010 ILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPI 2069
+D+ + QKT V G ++L +P F R + T T
Sbjct: 29737 TIDLSTMPQKTIHV-----PAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHT 29791
Query: 2070 RHRPRPYPPNVGQEALSQTTISWAPFQDTSEYIISCHPV-GTDEEPLQFRV---PGTST 2124
+ V + + +TTI +DT EY + V GT E ++ + PG T
Sbjct: 29792 K---------VAKLTIRETTI-----RDTGEYTLELKNVTGTTSETIKVIILDKPGPPT 29836
Score = 84.3 bits (207), Expect = 1e-15
Identities = 258/1201 (21%), Positives = 430/1201 (35%), Gaps = 157/1201 (13%)
Query: 908 PSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS------RNTF 961
P L EVT K + W PP G ++D V RL + + T
Sbjct: 21557 PPEGPLAVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQK--RETSRLAWTNVASEVQVTK 21613
Query: 962 AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL------DAPTNLQFVNETDSTVLV 1015
+VT L G Y F+V AV+ +PL ++ + D P N + T +++V
Sbjct: 21614 LKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVV 21673
Query: 1016 RWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVS-----KYPLRNLQPASEYTVSLVAIK 1070
W P + + + RR + Q + + +Y + L EY ++A
Sbjct: 21674 CWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAEN 21733
Query: 1071 G-NQESPKATGVF-----TTLQPGSSIPPYNTEVTETT---IVITWTP------APRIGF 1115
+P T F T +PG PP N V +T+ I I W + G+
Sbjct: 21734 AAGISAPSPTSPFYKACDTVFKPG---PPGNPRVLDTSRSSISIAWNKPIYDGGSEITGY 21790
Query: 1116 KLGVRPSQGGEAPREVTSDSG----SIVVSGLTPGVEYVYTIQVLRD---GQERDAPIVN 1168
+ + + E + VT +G S ++GLT EY I + G+ P
Sbjct: 21791 MVEIALPEEDEW-QIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTP 21849
Query: 1169 KVVTPLSPPT-NLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
K + PP L + + R P I G G SL++
Sbjct: 21850 KAEDRMLPPEIELDADLRKVVTIRACCTLRLFVP-IKGRPAPEVKWARDHGESLDKASIE 21908
Query: 1228 DQSSCTFDNLSPGLEYNVSVY--TVKDDK--ESVPISDTIIPAVPPPTDLRFTNIGPDTM 1283
SS T + ++ Y TV++ +S ++ ++ PP DL+ + ++
Sbjct: 21909 STSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSV 21968
Query: 1284 RVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD---NAVVLTNLLPGTEYVVSVSS 1340
+TW PP +D + + Y K E S ++ + + L G Y V +
Sbjct: 21969 TLTW-DPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLA 22027
Query: 1341 VYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR----ATITGYRIRH 1392
E P + P I D+T NS ++ W P + I GY +
Sbjct: 22028 ENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEM 22087
Query: 1393 HPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPR 1452
+ V + T+T L G EY + A N E + +Q +V + +
Sbjct: 22088 QTKGSDKWATCATVKVTE--ATITGLIQGEEYSFRVSAQN---EKGISDPRQLSVPVIAK 22142
Query: 1453 DLEVVAA------TPTSLL---ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
DL + A T T L + D P + +T+ + N P+++ T ++ST
Sbjct: 22143 DLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKD--NVPLKQTTRVNAESTE 22200
Query: 1504 TISGL--KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ----MQVTDVQDNS 1557
S L K + Y V + + + +++ +DKP +++ +V +S
Sbjct: 22201 NNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNV---IVLDKPGPPTGPVKMDEVTADS 22257
Query: 1558 ISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG--LQPTVEYVVS 1611
I++ W P S + Y V K T + TI+ L+ EY
Sbjct: 22258 ITLSWGPPKYDGGSSINNYIVE---KRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFR 22314
Query: 1612 VYAQNPSGES-----QPLVQTAVTNIDRPKGLAFTDVDV-DSIKIAWESPQGQVSRYRVT 1665
+ A+N G+S +P V + P G + DS+++ W P +
Sbjct: 22315 IAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIG 22374
Query: 1666 YSSPEDGIHELF-------PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ 1718
Y + + P P + T GL G EY V A + +P ++
Sbjct: 22375 YHLERKERNSILWVKLNKTPIPQTKFKTT---GLEEGVEYEFRVSAENIVGIGKPSKVSE 22431
Query: 1719 STAIPAPTDL----KFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINL 1770
P D + VT S++ QW P ++TGY V + MK
Sbjct: 22432 CYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFT 22491
Query: 1771 APDSSSVVVSGLMVATKYEVSVYALKDT-LTSRPAQ--GVVTTLENVSPPRRARVTDATE 1827
+ V+GL+ +YE V A + S P++ G +T + V PPR + +
Sbjct: 22492 NIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKD 22551
Query: 1828 TTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ-PGTDYKIYLYTL 1886
T + + + F+VDA P + IK D L+ TD+ L ++
Sbjct: 22552 TIVVHAGES-------FKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSL-SV 22603
Query: 1887 NDNAR--SSPVVIDASTAIDAPS---NLRFL-------------ATTPNSLLVSWQPPR- 1927
D R S ++ A S N++ L T ++W+PP
Sbjct: 22604 KDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQ 22663
Query: 1928 ---ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
+ I YI++ + VV +T L G EYT ++A+ EP
Sbjct: 22664 DGGSDIINYIVERRETSRLVWTVVDA-NVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEP 22722
Query: 1985 L 1985
L
Sbjct: 22723 L 22723
Score = 83.6 bits (205), Expect = 2e-15
Identities = 268/1312 (20%), Positives = 473/1312 (36%), Gaps = 176/1312 (13%)
Query: 812 DAPPDPT----VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN 863
D P PT + + + S+ ++W P+ + +T Y ++ + TE++
Sbjct: 26568 DRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVART 26627
Query: 864 SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV-EVTDVK 922
+ + L G +Y I A EN+ I T P P +V VT
Sbjct: 26628 MMKVMKLTTGEEYQFRIKA--ENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRES 26685
Query: 923 VTIMWTPPES----AVTGYRVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
+T+ W P S AV GY +++ N + + +L I R T +VT +S G+ Y F+V
Sbjct: 26686 ITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVI-RTTHFKVTTISAGLIYEFRV 26744
Query: 978 FAVSHGRESKPL-TAQQTTKLDA---PTNLQFVNETDSTVLVRWTPPR----AQITGYRL 1029
+A + KP ++ +DA P N++ + + ++V + W P ++ITGY
Sbjct: 26745 YAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYI- 26803
Query: 1030 TVGLTRRGQP-----RQYNVGPSVSKYPLRNLQPASEYTVSLVA--IKGNQESP-KATGV 1081
+ RR P + + +++ + L S+Y + A G+ +P + G
Sbjct: 26804 ---VERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGP 26860
Query: 1082 FTTLQ----PGSSIPPYNTEVTE----TTIV----ITWTPAPRI-GFKLGVRPSQGGEAP 1128
T + P +P TEV + T++ I+ PAP I +K
Sbjct: 26861 ITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVC 26920
Query: 1129 REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
E T+D SI++ Y +++ A I +++ PP
Sbjct: 26921 VENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTA 26980
Query: 1189 GVLTVSWERSTTPD----ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
+T+ W R D IT Y + T+ + + E H ++ T + G EY
Sbjct: 26981 EKITLLW-RPPADDGGAKITHYIVEKRETSRVVWSMVSE--HLEECIITTTKIIKGNEYI 27037
Query: 1245 VSVYTVKDDKESVPI-SDTIIP-----AVPPPTDLRFTNIGPDTMRVTWAPP---PSIDL 1295
V V P+ SD+++ PP T I ++M V W+ P D+
Sbjct: 27038 FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDI 27097
Query: 1296 TNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY---VVSVSSVYEQHESTPLRG 1352
+ + + K+ L + D +T L ++Y V +V++ + S P
Sbjct: 27098 SGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEF 27157
Query: 1353 RQKTGLDSPTG----IDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPRED 1404
+ P G I +D T +S T+ W P + +TGY + E G E
Sbjct: 27158 YKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVV----EIRQGEEEEW 27213
Query: 1405 RVPHSRNSITLT-----NLTPGTEYVVSIVALN-GREESPLLIGQQSTVSDVPR----DL 1454
++ + T NL PG Y + A+N + P+ + + D+ DL
Sbjct: 27214 TTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDL 27273
Query: 1455 EVVAATPTSLLISWDA-----------PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
+V T D P VT R G S S S
Sbjct: 27274 DVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYS----IENTDSSSLL 27329
Query: 1504 TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISV 1560
TI + + G G+ +S+ + + +D P+ ++QV V ++++
Sbjct: 27330 TIPQVTRNDTGKYILTIENGVGEPKSSTVSVKV-----LDTPAACQKLQVKHVSRGTVTL 27384
Query: 1561 KWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGP-DQTEMTIEGLQPTVEYVVSVYAQ 1615
W P SP+ Y + ++ T + + T + L + V A+
Sbjct: 27385 LWDPPLIDGGSPIINYVI--EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAE 27442
Query: 1616 NPSGESQPLVQT---AVTNIDRP-KGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPED 1671
N G +P T + P + L+ D S+ ++W P Y
Sbjct: 27443 NEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERK 27502
Query: 1672 GIHELFPAPDGEEDTAELQ--GLRPGSEYTVSVVALHDDMESQPL-IGTQSTAIPAPTDL 1728
G E + G T E++ L+ S V A ++ S P+ IG P +
Sbjct: 27503 GKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIG--------PITV 27554
Query: 1729 KFTQVTP-TSLSAQWTPPNVQLT---GYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMV 1784
K +TP LS P Q+T G+ V + K P I+ D + S +
Sbjct: 27555 KELIITPEVDLS---DIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVR 27611
Query: 1785 ATKYEVSV-YALKDTLTSRPAQ------------GVVTTLENVSPPRR----ARVTDATE 1827
+K E + ++K+ + V T+ + PP + R +
Sbjct: 27612 FSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKA 27671
Query: 1828 TTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVR-SYTITGLQPGTDYKIY 1882
++ +SW + IT + ++ QT + R ++ + L +Y+
Sbjct: 27672 DSVILSWDVPEDNGGGEITCYSIEK-RETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFR 27730
Query: 1883 LYTLNDNARSSPVVIDASTA------IDAPSNLRFLATTPNSLLVSWQPP----RARITG 1932
+ N S P+V A P T + + ++W P + +TG
Sbjct: 27731 VRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTG 27790
Query: 1933 YIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
+ ++ ++ S + V E TGL G +Y V A + S P
Sbjct: 27791 FHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSP 27842
Score = 83.2 bits (204), Expect = 3e-15
Identities = 293/1378 (21%), Positives = 491/1378 (35%), Gaps = 236/1378 (17%)
Query: 811 PDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVT 866
P P + V + S + W P + IT Y I + S + E N+
Sbjct: 15498 PSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVI---DKRDASRKKAEWEEVTNTAV 15554
Query: 867 -----LSDLQPGVQYNITI-----YAVEENQESTPVVIQQ--ETTGTPRSDTVPSPRDLQ 914
+ L P QY + Y + + +S VVIQ G P V
Sbjct: 15555 EKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKV------- 15607
Query: 915 FVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLP-GEHGQRLPISR----NTFAEVT 965
+ T + + WTPP S +TGY ++ P R PI++ V
Sbjct: 15608 -LARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVP 15666
Query: 966 GLSPGVTYYFKVFAVSH---GRESKP----LTAQQTTKLDAPTNLQFVNETDSTVLVRWT 1018
L GV Y F+ A++ G S+P + P+ + ++T S++ + W
Sbjct: 15667 RLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWK 15726
Query: 1019 PPR----AQITGYRLTV---GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIK- 1070
PP + I GY + + G T + + + + + + NL+ +Y + A+
Sbjct: 15727 PPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVNE 15786
Query: 1071 -GNQESPKATG------------VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKL 1117
G E TG VF + + VI P P+ ++
Sbjct: 15787 AGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEF 15846
Query: 1118 GVRPSQG---------GEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVN 1168
+ + +A E +S I++ Y+I ++ A
Sbjct: 15847 DGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRV 15906
Query: 1169 KVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD------ITGYRITTTPTNGQQGNSLE 1222
KV+ PP +L + ++ G +SW+ PD I GY I +G+
Sbjct: 15907 KVMDVPGPPKDLKV-SDITRGSCRLSWKM---PDDDGGDRIKGYVIEKRTIDGKAWTK-- 15960
Query: 1223 EVVHADQSSCTF--DNLSPGLEYNVSV-----YTVKDDKESVPISDTIIPAVPP--PTDL 1273
V+ D S TF +L +Y V + + E++ + P PP P L
Sbjct: 15961 --VNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKL 16018
Query: 1274 RFTNIGPDTMRVTWAPPPS---IDLTNFLVR---YSPVK---------NEEDVAELSISP 1318
+ I +T+ ++W PP + +T+++V + P N+ DV EL +
Sbjct: 16019 KIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTV 16078
Query: 1319 SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL---DSPTGIDFSDI--TANS 1373
D L+ G EY V +V S P D P ID +
Sbjct: 16079 ED-------LVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEG 16131
Query: 1374 FTVHWIA-----PRATITGYRIRH----------HPEHFSGRPREDR----VPHSRNSIT 1414
V+ +A P T+T ++ + H + +D +P SR S T
Sbjct: 16132 TNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDT 16191
Query: 1415 LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP--- 1471
Y ++ V G + + ++ + + + +SW P
Sbjct: 16192 GL-------YTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDD 16244
Query: 1472 -AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG-DSPA 1529
+ Y I E + V + P + T TI L G +Y + A G P
Sbjct: 16245 GGSKITNYVIEKREANRKTWVHVSSEP-KECTYTIPKLLEGHEYVFRIMAQNKYGIGEPL 16303
Query: 1530 SSKPISI-NYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVT---TTPKN- 1580
S+P + N + P + V+ V NS++V W SPVTGY + TT K
Sbjct: 16304 DSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRW 16363
Query: 1581 ---GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG---ESQPLVQTAVTNIDR 1634
P K T G + GL +Y VYA N +G S P +
Sbjct: 16364 KRVNRDPIKAMTLG---VSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIA 16420
Query: 1635 PKGLAF---TDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTA 1687
P G F TD S + W P +V+ Y V Y E+G E D E
Sbjct: 16421 PPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYK--EEGKEEWEKGKDKEVRGT 16478
Query: 1688 EL--QGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPT-SLSAQWTP 1744
+L GL+ G+ Y V A++ +P G + I ++K V+P L A
Sbjct: 16479 KLVVTGLKEGAFYKFRVRAVNIAGIGEP--GEVTDVI----EMKDRLVSPDLQLDASVRD 16532
Query: 1745 PNVQLTGYRVRVT-------PKEKTGPMKEINLAPDSS--SVVVSGLMVATKYEVS---V 1792
V G +R+ P T M E L +++ + +S MV + S V
Sbjct: 16533 RIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGV 16592
Query: 1793 YAL--KDTLTSRPAQGVVTTLENVSPPRRARVT-DATETTITISWRTKTET----ITGFQ 1845
Y+L K+ R +V L+ P + + T + ++W + + IT +
Sbjct: 16593 YSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYV 16652
Query: 1846 VDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND-------NARSSPVV 1896
++ ++ + TP+ T+ ++ T+ GL G Y + N + V+
Sbjct: 16653 IEKRESDRRAWTPVTYTVTR--QNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVI 16710
Query: 1897 IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPR 1952
+ T + P +L T N++ ++W PP+ + I Y+++ G+ V
Sbjct: 16711 REPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDN 16770
Query: 1953 PGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVT----LPHPNLH 2006
+ T+ GL+ G Y V A+ ++G+ K + +T L P LH
Sbjct: 16771 LLSRKYTVKGLKEGDTYEYRVSAVN-------IVGQGKPSFCTKPITCKDELAPPTLH 16821
Score = 82.0 bits (201), Expect = 6e-15
Identities = 266/1310 (20%), Positives = 442/1310 (33%), Gaps = 219/1310 (16%)
Query: 731 ITASSFVVSWVSASDTVSGFRVEYELSE-EGDEPQYLDLPSTAT--SVNIPDLLPGRKYI 787
++A +SW D Y + + E + ++ + S + IP LL G +Y+
Sbjct: 16229 VSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYV 16288
Query: 788 V-----NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----API 838
N Y I E + + + + P AP PTV V S+ V W P+ +P+
Sbjct: 16289 FRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPV 16348
Query: 839 TGYRIVYSPSVEGSSTELNLPETANSVTL------SDLQPGVQYNITIYAVEENQESTPV 892
TGY + + +N + ++TL + L G Y +YA+ P
Sbjct: 16349 TGYWLEMKDTTSKRWKRVN-RDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVG-PA 16406
Query: 893 VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
+ + P P + + T + W+PP S VTGY V+
Sbjct: 16407 SLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEE 16466
Query: 949 EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGR-----------ESKPLTAQQTTKL 997
+ R T VTGL G Y F+V AV+ E K +L
Sbjct: 16467 WEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQL 16526
Query: 998 DAPTNLQFVNETDSTV----LVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSV--SKY 1051
DA + V + V PP +T + R P++ + + S
Sbjct: 16527 DASVRDRIVVHAGGVIRIIAYVSGKPPPT------VTWNMNERTLPQEATIETTAISSSM 16580
Query: 1052 PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT-EVTETTIVITWTP- 1109
++N Q + + SL+A E K V PG P+ +T + +TW
Sbjct: 16581 VIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSP 16640
Query: 1110 -----APRIGFKLGVRPS-QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD----- 1158
+P + + R S + P T + V GL G Y + I
Sbjct: 16641 EDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGP 16700
Query: 1159 -GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTN 1214
+ +A ++ + +T P +L ++ +T++W + +I Y + +
Sbjct: 16701 FVETSEALVIREPITVPERPEDLEVK-EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIG 16759
Query: 1215 GQQGNSLEEVVHADQSSCTFDNLSPG--LEYNVSVYTV----KDDKESVPISDTIIPAVP 1268
++ + + + T L G EY VS + K + PI T +
Sbjct: 16760 TEKFHKVTN-DNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPI--TCKDELA 16816
Query: 1269 PPT---------DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSI 1316
PPT +R T R + P P + S K+E DV E I
Sbjct: 16817 PPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKV---------SWFKDEADVLEDDRTHI 16867
Query: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP----TGIDFSDITAN 1372
+ + L + V E + Q +D P + F ++T +
Sbjct: 16868 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKD 16927
Query: 1373 SFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP----HSRNSITLTNLTPGTEYVVSI 1428
+ W P G +I ++ ++ +P ++ + ++ L G +Y+ I
Sbjct: 16928 YMVISW-KPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRI 16986
Query: 1429 VALNGREESPLLIG------QQSTVSDVPRDLEVVAATPTSLLISWDAP----------- 1471
A N S L+ + V D P V T S L++W+ P
Sbjct: 16987 HAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYI 17046
Query: 1472 -----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT--GR 1524
++ R+ R+T P +F VP L G Y V A G
Sbjct: 17047 LEKRETMSKRWARVTKDPI---HPYTKFRVP---------DLLEGCQYEFRVSAENEIGI 17094
Query: 1525 GDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRVTTT 1577
GD SKP+ + I KPS + D NS+ + W P S + GY +
Sbjct: 17095 GDPSPPSKPVFA--KDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGY-IVEY 17151
Query: 1578 PKNGPGPTKTKTAGPD---QTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LVQT 1627
K G + P+ +T+ + GL+ Y V A N +GES P LV+
Sbjct: 17152 QKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKD 17211
Query: 1628 AV--------TNIDRPKGLAFTDV--------DVDSIKIAWESPQGQVSRYRVTYSSPED 1671
+ N+ R + + D V K+ W+ +P
Sbjct: 17212 RLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVG 17271
Query: 1672 GIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFT 1731
E+ A + L P TVSV L D P DL+ +
Sbjct: 17272 SKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG------------PPRDLEVS 17319
Query: 1732 QVTPTSLSAQWTPP----NVQLTGYRVR-------------VTPKEKTGPMKEINLAPDS 1774
++ S W P +T Y V T K+K+ K +N
Sbjct: 17320 EIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLN----E 17375
Query: 1775 SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISW 1834
+ + + +Y + T +P + + L PP+ D +T +++ W
Sbjct: 17376 GNQYLFRVAAENQYGRGPF----VETPKPIK-ALDPLHPPGPPKDLHHVDVDKTEVSLVW 17430
Query: 1835 ----RTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYK 1880
R ITG+ V+ Q I+ ++ +TGLQ G Y+
Sbjct: 17431 NKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLEC-VVTGLQQGKTYR 17479
Score = 80.9 bits (198), Expect = 1e-14
Identities = 248/1194 (20%), Positives = 435/1194 (36%), Gaps = 142/1194 (11%)
Query: 908 PSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE 963
P +Q VT K ++ W+PP S ++ Y V+ + + N+ +
Sbjct: 23721 PPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSL-K 23779
Query: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA------PTNLQFVNETDSTVLVRW 1017
VT L G Y F++ AV+ +PL + + P +L+ N ++ V W
Sbjct: 23780 VTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCW 23839
Query: 1018 TPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQ---------PASEYTVSLVA 1068
P + G +G + R +K + +L+ E+ VS
Sbjct: 23840 NRPDSD--GGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAEN 23897
Query: 1069 IKGNQESPKATGVFTTLQPGSSI-PPYNTEVTETT---IVITWTP------APRIGFKLG 1118
G E AT + P PP N + +TT I + W + +G+ +
Sbjct: 23898 AAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVE 23957
Query: 1119 VRPSQGGEAPREVTSDSGSIV----VSGLTPGVEYVYTIQVLRD---GQERDAPIVNKVV 1171
+ + E + VT +G V +S LT EY + L G+ P K
Sbjct: 23958 ICKADEEEW-QIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPE 24016
Query: 1172 TPLSPPTNLHLEANPDTGVLT---------VSWERSTTPDITGYRITTTPTNGQQGNSLE 1222
L P L L++ G++ + ++ TP+IT R T+ Q +E
Sbjct: 24017 DKLEAP-ELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQ---IE 24072
Query: 1223 EVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDT 1282
+ V+ Q S + + +Y + + K + ++ ++ PP +L + D+
Sbjct: 24073 KGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAF-VTVKVLDTPGPPQNLAVKEVRKDS 24131
Query: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEED---VAELSISPSDNAVVLTNLLPGTEYVVSVS 1339
+ W PP ID + Y K E A +S S + + NL G Y V
Sbjct: 24132 AFLVWEPP-IIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVM 24190
Query: 1340 SVYEQHESTPLR---GRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIR 1391
+ E P+ + SP G + +D++ S ++ W P + + GY +
Sbjct: 24191 AENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE 24250
Query: 1392 HHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSIVALNGREES-PLLIGQQSTVSD 1449
P+ G + V S+ + +T L+ G EY + A N + +S P ++G D
Sbjct: 24251 MQPK---GTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKD 24307
Query: 1450 VPRDLEVVAATPTSLL-----ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT 1504
+ + T + + + P + I++ + G P+++ T + TAT
Sbjct: 24308 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDG--EPLKQTTRVNVEETAT 24365
Query: 1505 --ISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVK 1561
+ +K G Y VT + +++ +S+ + P ++ +V + + +
Sbjct: 24366 STVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVIS 24425
Query: 1562 WLPSS----SPVTGYRV-----TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV 1612
W P + ++ Y V TTT + T +T + I L+ EY +
Sbjct: 24426 WEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTT------IKITKLKTGTEYQFRI 24479
Query: 1613 YAQNPSGESQPLVQTAVT-----NIDRPKGLAF-TDVDVDSIKIAWESPQGQVSRYRVTY 1666
+A+N G+S PL AV P G F T + D + + W P + Y
Sbjct: 24480 FAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGY 24539
Query: 1667 SSPEDGIHELF-------PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQS 1719
+ + + P D + T GL G EY V A + +P ++
Sbjct: 24540 HLEQKEKNSILWVKLNKTPIQDTKFKTT---GLDEGLEYEFKVSAENIVGIGKPSKVSEC 24596
Query: 1720 TAIPAPTD----LKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLA 1771
P D + +T +++ +W P ++TGY V MK
Sbjct: 24597 FVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTN 24656
Query: 1772 PDSSSVVVSGLMVATKYEVSVYALKDTLT-SRP--AQGVVTTLENVSPPRRAR------- 1821
+ VSGL+ +YE V A S P + G +T + + P +
Sbjct: 24657 VLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDV 24716
Query: 1822 -VTDATET-TITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ-PGTD 1878
V A ET + R K + D +T + IK ++ T+ TD
Sbjct: 24717 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELE-ETAARMEIKSTIQKTTLVVKDCIRTD 24775
Query: 1879 YKIYLYTLND--NARSSPVVIDASTAIDAPSN-LRFLATTPNSLLVSWQPP----RARIT 1931
Y+ L++ +S P+ + P L+ T ++W PP A I+
Sbjct: 24776 GGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANIS 24835
Query: 1932 GYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 1985
YII+ + V + +T L PG EY V+A+ EPL
Sbjct: 24836 HYIIEKRETSRLSWTQVSTEVQAL-NYKVTKLLPGNEYIFRVMAVNKYGIGEPL 24888
Score = 78.6 bits (192), Expect = 7e-14
Identities = 278/1375 (20%), Positives = 475/1375 (34%), Gaps = 200/1375 (14%)
Query: 797 GEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGS 852
G +++ + P P D V ++ S + W P + IT Y +
Sbjct: 17296 GSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ 17355
Query: 853 STELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRD 912
+ L+ S L G QY + A + V + P+D
Sbjct: 17356 WSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKD 17415
Query: 913 LQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE----V 964
L V+V +V+++W P+ S +TGY V+ E G + I T V
Sbjct: 17416 LHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEY------QEEGTQDWIKFKTVTNLECVV 17469
Query: 965 TGLSPGVTYYFKVFA---VSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
TGL G TY F+V A V G + + KL P+ V + V+ T R
Sbjct: 17470 TGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVR 17529
Query: 1022 --AQITGYRL-TVGLTRRGQPRQYNVGPSV------SKYPLRNL--QPASEYTVSLVAIK 1070
A I G + T T G + + +V S ++N + EY +++
Sbjct: 17530 FPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV---- 17585
Query: 1071 GNQESPKATGVFTTLQ--PGSSIPPYNT-EVTETTIVITWTPAPRIGFKLGVRPSQGGEA 1127
N K V T+ PG P N +VT + I+W P P G +
Sbjct: 17586 SNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQP-----------PKDDGGS 17634
Query: 1128 P--------REVTSDSGSIVVSG----------LTPGVEYVYTIQV---LRDGQERDA-P 1165
P ++ D+ +V SG L G EYV+ ++ + G D+ P
Sbjct: 17635 PVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTP 17694
Query: 1166 IVNK-VVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSL 1221
V K +P SPP + + TVSW + ITGY + G+
Sbjct: 17695 TVAKHKFSPPSPPGK-PVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVN 17753
Query: 1222 EEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVP-----PPTDLRFT 1276
+ + + T E+ V + + P SD I P PP + +
Sbjct: 17754 KTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLK 17813
Query: 1277 NIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDN-----AVVLTNLLPG 1331
+ +T + W P S D + ++ Y + A+ + D A + L+ G
Sbjct: 17814 DKSRETADLVWTKPLS-DGGSPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEG 17872
Query: 1332 TEYVVSVSSVYEQHESTPLRGRQKT---GLDSPTGIDFSDITANSFTVHWIAPRATITGY 1388
EY + + E P + + P ++ D+T + I
Sbjct: 17873 NEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVEL-DVTCRDVITVRVGQTIRILA- 17930
Query: 1389 RIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE-------------YVVSIVALNGRE 1435
R++ PE +E +V + L P E Y++S +G
Sbjct: 17931 RVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHA 17990
Query: 1436 ESPLLIGQQSTVSDVP---RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQ 1492
+ ++ V D P ++L+V T + ISW+ P + G + + +
Sbjct: 17991 QGSAIVN----VLDRPGPCQNLKVTNVTKENCTISWENP--------LDNGGSEITNFIV 18038
Query: 1493 EFTVPGSKSTATISG----------LKPGVDYTITVYAVTGRGDSPASSKPISINYRTEI 1542
E+ P K + ++ L +Y V A G P I I
Sbjct: 18039 EYRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPI 18098
Query: 1543 DKPSQ---MQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 1595
D+P + + + D + +KW SP Y V K + +T
Sbjct: 18099 DRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKET 18158
Query: 1596 EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSI------- 1648
++ Y V +N GES V+T + D+ + +
Sbjct: 18159 HYMVDRCVENQIYEFRVQTKNEGGESD-WVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGD 18217
Query: 1649 KIAWESPQGQVSRYRVTYSSPEDGIHELFPAP----DGEEDTAELQGLRP----GSEYTV 1700
I E+ V ++ +D +L +P D D+++ + G +Y V
Sbjct: 18218 TIRLEAGVRGKPFPEVAWTKDKDAT-DLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVV 18276
Query: 1701 SVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKE 1760
+ + + P +LK V+ + W PP G ++ E
Sbjct: 18277 TATNTAGSFVAYATVNVLDKPGPV-RNLKIVDVSSDRCTVCWDPPEDD-GGCEIQNYILE 18334
Query: 1761 KTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV------ 1814
K K + + S++V+ G V E + Y + ++ G T + V
Sbjct: 18335 KC-ETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKY 18393
Query: 1815 ---SPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQ--TPIQRTIKPDV 1865
P VT ++ +T+ W ++ITG+ ++ + P+ ++ P+
Sbjct: 18394 DKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPE- 18452
Query: 1866 RSYTITGLQPGTDYKIYLYTLND------NARSSPVVI-DASTAIDAPSNLRFLATTPNS 1918
R + L P +Y+ + N+ + S PVV D P+N R + TT +S
Sbjct: 18453 RRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHS 18512
Query: 1919 LLVSWQPP----RARITGYIIKYEK--PGSPPREVVPRPRPGV----TEATITGLEPGTE 1968
+ + W P A I GY+++ + P E R E T+T L+ E
Sbjct: 18513 ITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQE 18572
Query: 1969 YTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFV 2023
Y V A NQ +G + EL + + P L PEI D+ ++++K V
Sbjct: 18573 YEFRVCA--QNQ-----VGIGRPAELKEAIK-PKEILEPPEI-DLDASMRKLVIV 18618
Score = 78.6 bits (192), Expect = 7e-14
Identities = 169/767 (22%), Positives = 275/767 (35%), Gaps = 120/767 (15%)
Query: 601 PLQTYPSSSGPVEVFITETPSQPN-------SHPIQWNAPQ---PSHISKYILRWRPKNS 650
P +T P VF+ PS+P + I W P + I+ Y + ++ +
Sbjct: 26068 PSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDD 26127
Query: 651 VGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT 710
WK + YTI GL G Y ++ S+ + G + + +S P +
Sbjct: 26128 TD-WKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASD-------PSDSSDPQIAKE 26179
Query: 711 VTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVS--GFRVEYELSEEGDEP----Q 764
E PL +E+ + V + S + TV G V L + D
Sbjct: 26180 REEE-----PLFDID---SEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA 26231
Query: 765 YLDLPSTATSVNIPDLL--PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV 822
Y+D + TS+ I + KY + + + +L++ T P P + TV V
Sbjct: 26232 YVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGP--PTNITVQDV 26289
Query: 823 DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNI 878
S V+ W P+ AP+ Y I + + + + S +++LQ G Y
Sbjct: 26290 TKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYF 26349
Query: 879 TIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAV 934
+ E P ++ G ++ P L ++ V++ W PE S +
Sbjct: 26350 RVSGENEFGVGIPAETKE---GVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRI 26406
Query: 935 TGYRVDVIPVNLPGEHGQR----LPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-- 988
Y V+ + E GQ+ ++++T V+GL Y+F+VFA + S P
Sbjct: 26407 VHYVVEAL------EKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRE 26460
Query: 989 -LTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
L + P + N TV VR G L V + G+P V S
Sbjct: 26461 LLLPVLIKEQLEPPEIDMKNFPSHTVYVR--------AGSNLKVDIPISGKPLP-KVTLS 26511
Query: 1048 VSKYPLR-NLQPASEYTV---------SLVAIKGNQESPKATGVFTTL---------QPG 1088
PL+ ++ +E T S+ A G E A TT +PG
Sbjct: 26512 RDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPG 26571
Query: 1089 SSI-PPYNTEVTETTIVITWTPAPRIG-------FKLGVRPSQGGEAPREVTSDSGSIVV 1140
P +++TE ++ + W P G L S T + V
Sbjct: 26572 PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKV 26631
Query: 1141 SGLTPGVEYVYTIQV-----LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
LT G EY + I+ + D + V T PP+ + N +TV W
Sbjct: 26632 MKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWV-TNVTRESITVGW 26690
Query: 1196 ERSTT---PDITGYRITTTPTNG---QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249
+ + GY + N Q+ N L V+ T +S GL Y VY
Sbjct: 26691 HEPVSNGGSAVVGYHLEMKDRNSILWQKANKL--VIRTTHFKVT--TISAGLIYEFRVYA 26746
Query: 1250 V------KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP 1290
K S P+ I A PP ++R T+I +++ ++W P
Sbjct: 26747 ENAAGVGKPSHPSEPV--LAIDACEPPRNVRITDISKNSVSLSWQQP 26791
Score = 66.2 bits (160), Expect = 4e-10
Identities = 301/1561 (19%), Positives = 557/1561 (35%), Gaps = 218/1561 (13%)
Query: 628 IQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W+AP S ++ + + + +NS+ K T P Y GL G+ Y+ ++ +
Sbjct: 27775 LTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAE 27834
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
G S+P + T +P P + ++T + + W
Sbjct: 27835 NSAG-------------LSSPSDPSKFTLAVSPVDP--PGTPDYIDVTRETITLKWNPPL 27879
Query: 745 DTVSGFRVEYELSEEGDEPQYLDLPSTATS---VNIPDLLPGRKYIVNVYQ------ISE 795
V Y + + +++ T S + L PG +Y + IS
Sbjct: 27880 RDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISP 27939
Query: 796 DGEQSLILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWS--RPQAPITGYRIV----YS 846
+ S I+ T P P V+ + D I+ R +A + G + +
Sbjct: 27940 PSQSSGIIMTRDENVP-----PIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFK 27994
Query: 847 PSVE-GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES--TPVVIQQETTGTPR 903
VE + + + S +L ++ + + +Y VE S I+ + TP
Sbjct: 27995 DGVEIEKRMNMEITDVLGSTSLF-VRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPG 28053
Query: 904 SDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVNLPGEHGQRLPISRN 959
P ++F +T K+T+ W P + +T Y ++ +
Sbjct: 28054 KVVGP----IRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQ 28109
Query: 960 TFAEVTGLSPGVTYYFKVFAVSH---GR--ESKPLTAQ-QTTKLDAPTNLQFVNETDSTV 1013
++ + L G Y F+V AV+ GR +S P+ AQ Q T DAP + N T +++
Sbjct: 28110 SYTAIK-LINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSI 28168
Query: 1014 LVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN-------LQPASEYTVSL 1066
+ W P + G + + R + + +SK P+ L +EY +
Sbjct: 28169 TLTWARPESD-GGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHV 28227
Query: 1067 VAIKGNQESPKATGVFTTLQ-------PGSSIPPYNTEVTETTIVITWTPA------PRI 1113
+A P A+G+ ++ PG T+ ++TT+ + W+ I
Sbjct: 28228 MAENAAGVGP-ASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEII 28286
Query: 1114 GFKLGVRPSQGGEAPREVTSDS---GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
G+ + + + G+ +V +++ V+ L G EY + + + + D+ V
Sbjct: 28287 GYIIEMCKADLGDW-HKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGT 28345
Query: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT----NGQQGNSLEEVVH 1226
+ + T L+ + + V ++ Y+ TPT SL +H
Sbjct: 28346 IKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIH 28405
Query: 1227 ADQSSCTFD----NLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDT 1282
S T N + +Y ++V K S+ + ++ PP + F ++ +
Sbjct: 28406 TTDSFSTLTVENCNRNDAGKYTLTVENNSGSK-SITFTVKVLDTPGPPGPITFKDVTRGS 28464
Query: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLPGTEYVVSVS 1339
+ W P +D + Y K E +S + + +L G Y VS
Sbjct: 28465 ATLMW-DAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVS 28523
Query: 1340 SVYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR----ATITGYRIR 1391
+V E P + P +D D + +S + W+ P + ITGY +
Sbjct: 28524 AVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLE 28583
Query: 1392 HHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV 1450
+ G H++ + T+ L TEY + A N S S +
Sbjct: 28584 MRQK---GSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKE 28640
Query: 1451 PR-----DLEVV--------AATPTSL---LISWDAPAVTVRYYRITYGETGGNSPVQEF 1494
P+ DL + A +P ++ + AP VT + + ET S
Sbjct: 28641 PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVS----I 28696
Query: 1495 TVPGSKSTATISGLKPGVD--YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQM---- 1548
T ++T T+ G Y +T+ ++ A K S+ I +P +
Sbjct: 28697 TTTKDRTTLTVKDSMRGDSGRYFLTL-------ENTAGVKTFSVTV-VVIGRPGPVTGPI 28748
Query: 1549 QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
+V+ V S + W + +T Y + ++G + + +T++ + L
Sbjct: 28749 EVSSVSAESCVLSWGEPKDGGGTEITNY-IVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 28807
Query: 1605 TVEYVVSVYAQNPSGESQPLVQTAV------TNIDRPKGLAFTDVDVDSIKIAWESPQGQ 1658
+EY V ++N G S+PL + P V +++ I WE P
Sbjct: 28808 YMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHD 28867
Query: 1659 VSRYRVTYSSPEDGIHELFPAPDGE----EDTAELQGLRPGSEYTVSVVALH------DD 1708
+ Y + + + + + E ++ GL G EY AL+
Sbjct: 28868 GGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKAS 28927
Query: 1709 MESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGP 1764
S+P++ + AP + T VT +++S W+ P ++ GY + P + G
Sbjct: 28928 EASRPIMA--QNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGD 28985
Query: 1765 ---MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT-LTSRPAQ--GVVTTLENVSPPR 1818
+K + V+ L YE V A + S+ ++ G VT + +PP+
Sbjct: 28986 GRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPK 29045
Query: 1819 RARVTDATETTITISWRTKTETITGFQVDAVP------ANGQTPIQRTIKPDV-----RS 1867
DA ++ R ++ + V P G + K + R+
Sbjct: 29046 AE--LDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRA 29103
Query: 1868 YTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP---SNLRFLATTPNSLLVSWQ 1924
+ +D Y T+ NA + V +D+P L T ++W
Sbjct: 29104 TAVIKFCDRSDSGKYTLTVK-NASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWS 29162
Query: 1925 PPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKN-- 1978
P+ A IT YI++ + +V P ++ +T L EY V A+
Sbjct: 29163 LPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLS-YVVTRLIKNNEYIFRVRAVNKYG 29221
Query: 1979 ---NQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFV--THPGYDTGNG 2033
+SEP++ R T+P P P I + T ++ + T P D GN
Sbjct: 29222 PGVPVESEPIVARNS-------FTIPSP----PGIPEEVGTGKEHIIIQWTKPESDGGNE 29270
Query: 2034 I 2034
I
Sbjct: 29271 I 29271
Score = 60.8 bits (146), Expect = 1e-08
Identities = 178/828 (21%), Positives = 291/828 (35%), Gaps = 149/828 (17%)
Query: 1263 IIPAVPPPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPS 1319
+I P +L T + + W P + + ++V +K + V + S
Sbjct: 13086 VIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAES 13145
Query: 1320 DNAVVLTNLLPGTEYVVSVSS-----VYEQHES-TPLRGRQKTGLDSPT-GIDFSDITAN 1372
V G EY+ VS+ E E+ P+ R K + P + +D+
Sbjct: 13146 CEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRF 13205
Query: 1373 SFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSI 1428
++ W P A IT Y I + V S T+T++ G EY +
Sbjct: 13206 GVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRV 13265
Query: 1429 VALNGREESPLLIGQQSTVSDV------------PRDLEVVAATPTSLLISWDAP----A 1472
R ++ + +G+ S + P +L T +S+ + W+ P
Sbjct: 13266 -----RAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGG 13320
Query: 1473 VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSK 1532
+ Y I E G ++ ++ + T ++GL+ G Y V A G S S
Sbjct: 13321 SPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEI 13380
Query: 1533 PISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSS--PVTGYRVTTTPKNGPGPTKTKTA 1590
+ +P+ M ++ +D + P + P TGY P PT T
Sbjct: 13381 LGPLTADDAFVEPT-MDLSAFKDGLEVIVPNPITILVPSTGY---------PRPTATWCF 13430
Query: 1591 GPDQTE----MTIEGLQPTVEYVVSVYAQNPSG----ESQPLVQTAVTNID--------R 1634
G E + ++ L E V+S ++ G + + V+T ID
Sbjct: 13431 GDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSA 13490
Query: 1635 PKGLAFTDVDVDSIKIAWESPQ----GQVSRY--------RVTYSSPEDGIHEL-FPAPD 1681
PK L F D+ DS+ + WE P ++ Y R T++ D + +L F PD
Sbjct: 13491 PKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPD 13550
Query: 1682 GEEDTAELQGLRPGSEYTVSVVALHDDMESQPL-------IGTQSTAIPAPTDLKFTQVT 1734
L G EY V A + +P + T +T P ++K+ T
Sbjct: 13551 ----------LVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRT 13600
Query: 1735 PTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKY 1788
S+ W PP ++ GY V P+ G K + + + V+GL Y
Sbjct: 13601 ANSIFLTWDPPKNDGGSRIKGYIVERCPR---GSDKWVACGEPVAETKMEVTGLEEGKWY 13657
Query: 1789 EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT-----------ITISWRTK 1837
V AL S+P++ P + D E +T+ TK
Sbjct: 13658 AYRVKALNRQGASKPSR----------PTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTK 13707
Query: 1838 TE---TITGFQVDAVPANGQTPIQRTIKPDVR----------SYTITGLQPGTDYKIYLY 1884
E T+TG P T +K D R + TI + +
Sbjct: 13708 IELPATVTG---KPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIE 13764
Query: 1885 TLNDNARSSPVV-IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEK 1939
+N R++ VV ++ P+ T S L++W PPR ++IT Y+++
Sbjct: 13765 AVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRA 13824
Query: 1940 PGSPPREVVPRPRPGV--TEATITGLEPGTEYTIYVIALKNNQKSEPL 1985
S EV + V T T L P EY V A EP+
Sbjct: 13825 TDS---EVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPV 13869
Score = 52.8 bits (125), Expect = 4e-06
Identities = 80/336 (23%), Positives = 120/336 (35%), Gaps = 46/336 (13%)
Query: 602 LQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKN-SVGRWKEA 657
++ Y S P + +T+ ++ S + W+AP S I+ Y++ R + W+E
Sbjct: 15492 VEVYDRPSPPRNLAVTDIKAE--SCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEV 15549
Query: 658 TIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
T Y I L P YE ++ ++ +YG + + D V + P
Sbjct: 15550 TNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSD-------KVVIQDPYRLPGPP 15602
Query: 718 FSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA----- 772
P V T S +VSW D Y L + + Y S A
Sbjct: 15603 GKPKVLAR------TKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKV 15656
Query: 773 ----TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPPD-PTVDQV 822
N+P LL G KY +N I E S P PP P V
Sbjct: 15657 GLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDK 15716
Query: 823 DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPE---TANSVTLSDLQPGVQ 875
+SI + W P +PI GY + +N P+ T + +L+ +
Sbjct: 15717 TKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRK 15776
Query: 876 YNITIYAVEENQESTPVVIQQETTG-TPRSDTVPSP 910
Y + AV E ES P +TTG P +D P
Sbjct: 15777 YRFRVKAVNEAGESEP----SDTTGEIPATDIQEEP 15808
Score = 43.9 bits (102), Expect = 0.002
Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 22/204 (10%)
Query: 717 PFSPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTA 772
P P+V + + +S V+SW +D ++ + VE ++EG E Q + +
Sbjct: 30726 PTGPIV-----IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISV 30780
Query: 773 TSVNIPDLLPGRKYIV-----NVYQISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTS 826
T+ I +L Y N + IS+ E S+++ S P AP PT+ V S
Sbjct: 30781 TTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDS 30840
Query: 827 IVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSV-TLSDLQPGVQYNITIY 881
VV W P A I Y + + + E +V ++ +L G++Y +
Sbjct: 30841 CVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVK 30900
Query: 882 AVEENQESTPVVIQQETTGTPRSD 905
ES I + TP+SD
Sbjct: 30901 CENLGGESEWSEISEPI--TPKSD 30922
Score = 41.2 bits (95), Expect = 0.012
Identities = 92/413 (22%), Positives = 157/413 (38%), Gaps = 51/413 (12%)
Query: 1285 VTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSV 1341
++W PP +TN++V K + +S + S + NL Y VS+
Sbjct: 30742 ISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQ 30801
Query: 1342 YEQHESTPLRGRQKTGLDSPTGID-------FSDITANSFTVHWIAPRATITGYRIRHHP 1394
S PL + SP + +T +S V W P A+ G +IR++
Sbjct: 30802 NTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAW-KPPASDGGAKIRNYY 30860
Query: 1395 EHFSGRPREDRVPHSRNSITLT-----NLTPGTEYVVSIVA--LNGREESPLLIGQQSTV 1447
+ + + + I T NL G EY + L G E + +
Sbjct: 30861 LEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPK 30920
Query: 1448 SDVP----------RDLEVVAATPTSLLISWDA-PAVTVRYYRITYGET----GGNSPVQ 1492
SDVP R+L V + +L+ P V++YR G+ G +Q
Sbjct: 30921 SDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYR--QGKEIIADGLKYRIQ 30978
Query: 1493 EFTVPGSKSTATISGLKPGVDYTITVYAV--TGRGDSPASSKPISINYRTEIDKPSQMQ- 1549
EF G I+ + D TVY V T +G S + + + + +I P ++
Sbjct: 30979 EFK--GGYHQLIIASV---TDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEG 31033
Query: 1550 ---VTDVQDNSISVKWLPSSS---PVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
V ++ +S+K +P S PV ++ + G + + + G++
Sbjct: 31034 MGAVHALRGEVVSIK-IPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVE 31092
Query: 1604 PTVEYVVSVYAQNPSGESQPLVQTAVTNI-DRPKGLAFTDVDVDSIKIAWESP 1655
V A+N G Q V+ V ++ D P+G+ +DV DS+ + W P
Sbjct: 31093 RKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEP 31145
Score = 39.3 bits (90), Expect = 0.046
Identities = 46/194 (23%), Positives = 75/194 (38%), Gaps = 22/194 (11%)
Query: 2062 PPTTATPIRH-RPRPYPPNVGQEALSQTTISWAPFQD-----TSEYIISCHPVGTDEEPL 2115
P T TP+ P PP V S ++SW+ +D + Y I TD+
Sbjct: 30319 PVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVR 30378
Query: 2116 QFRVPGTSTSATLTGLTRGATYNIIVEALKD---QQRHKVREEVVTVGNSVNEGLNQPTD 2172
+ T+T T+TGL A Y + A D + E VV + ++P+
Sbjct: 30379 HNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVV-----CKDPFDKPSQ 30433
Query: 2173 DSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEK 2232
+ ++S +V +WE+ G K + LG+ + + S W N K
Sbjct: 30434 PGELEILSISKDSVTLQWEKPECDGGK---EILGYWVEYRQSGDSAWKKSNKERIK---- 30486
Query: 2233 WDRQGENGQMMSCT 2246
D+Q G ++ T
Sbjct: 30487 -DKQFTIGGLLEAT 30499
Score = 37.7 bits (86), Expect = 0.13
Identities = 36/131 (27%), Positives = 53/131 (40%), Gaps = 8/131 (6%)
Query: 894 IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGE 949
I Q+T +D PR ++ +V+ V + WT P S +T Y V+ E
Sbjct: 31109 IDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATT--AE 31166
Query: 950 HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ--TTKLDAPTNLQFVN 1007
R+ +R T V L +Y F+V A + SKP + TK D + +
Sbjct: 31167 RWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDE 31226
Query: 1008 ETDSTVLVRWT 1018
E D T V T
Sbjct: 31227 EVDETREVSMT 31237
Score = 35.0 bits (79), Expect = 0.87
Identities = 38/169 (22%), Positives = 71/169 (42%), Gaps = 17/169 (10%)
Query: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL-PSS---SPVTGYRV 1574
Y V + K + ++ D P ++V+DV +S+++ W P+S S +T Y V
Sbjct: 31099 YVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIV 31158
Query: 1575 TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL--VQTAVTNI 1632
+ A +T T+ L Y V A+N G S+P + +T
Sbjct: 31159 EKCATTAERWLRVGQA--RETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKE 31216
Query: 1633 DRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPD 1681
D+ + + + D +VD + +VS + ++SS ++ + A D
Sbjct: 31217 DKTRAMNY-DEEVDETR--------EVSMTKASHSSTKELYEKYMIAED 31256
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 154 bits (388), Expect = 1e-36
Identities = 299/1365 (21%), Positives = 509/1365 (37%), Gaps = 169/1365 (12%)
Query: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPI-QWNAPQP---SHISKYILRW 645
YG G+ +P+ S + P I E H I QW P+ + IS Y++
Sbjct: 22915 YGPGVPV-ESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDK 22973
Query: 646 RPKNSVGRWKEATIPGHLNSYTIK--GLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTS 703
R K S+ RW + +K L G Y+ ++ ++ G+ E +
Sbjct: 22974 REKKSL-RWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSE--------- 23023
Query: 704 TPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELS-EEGDE 762
SN ++ ++P ++ V + T S ++W V Y L +E D
Sbjct: 23024 ---ASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDT 23080
Query: 763 PQYLDLPSTATSVN----IPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT 818
Q+ + + AT N +PDL G+KY V ++ G S ++ + P
Sbjct: 23081 DQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPD 23140
Query: 819 VDQVDDT--SIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP-----ETANSVTLSDLQ 871
++ DD ++ +R + P + S ++L +T S +L +
Sbjct: 23141 LELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVD 23200
Query: 872 PGVQYNITIYAVE-ENQE----STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
+Y+ Y +E ENQ +T +V +T G P P ++ EV+ VTI
Sbjct: 23201 KVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPG-------PCP-SVKVKEVSRDSVTIT 23252
Query: 927 WTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH 982
W P + V Y V+ + S+ T ++GL G YYF+V +
Sbjct: 23253 WEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSK-TLYRISGLVEGTMYYFRVLPENI 23311
Query: 983 GRESKPLTAQQTTKLD----APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLT 1034
+P + P L+ V+ T STV + W P +++TGY L
Sbjct: 23312 YGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEA--C 23369
Query: 1035 RRGQPRQYNV---GPSVSKYPLRNLQPASEYTVSLVAI--KGNQESPKATGVFTTLQPGS 1089
+ G R V P+V ++ + +L +Y + A KG E P+ T T+Q
Sbjct: 23370 KAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSE-PRETVTAVTVQDLR 23428
Query: 1090 SIPPYNTEV-------------TETTIVITWTPAPRIG-FKLGVRPSQGGEAPREVTSDS 1135
+P + E I I P P F G + + E +
Sbjct: 23429 VLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKV 23488
Query: 1136 GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
+ + T YT+++ I ++ PPT D +T+SW
Sbjct: 23489 AKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISW 23548
Query: 1196 ERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV----- 1247
E ++GY + + + E V +S+ F L+ G EY V
Sbjct: 23549 EPPELDGGAPLSGYVVEQRDAHRPGWLPVSESV--TRSTFKFTRLTEGNEYVFRVAATNR 23606
Query: 1248 YTVKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYS 1303
+ + +S I +P PP L+ ++ D M +TW PP +T ++V
Sbjct: 23607 FGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERK 23666
Query: 1304 PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR-GRQKTGLD--- 1359
V+ + V + + T L G EY V+++ + P R + +D
Sbjct: 23667 EVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIA 23726
Query: 1360 ---SPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNS 1412
P +D T S ++ W P + +TGY I + + P
Sbjct: 23727 PPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIRE 23786
Query: 1413 ITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAAT--PTSLLISWDA 1470
TLT+L G EY ++A N G ++VP ++V P L
Sbjct: 23787 YTLTHLPQGAEYRFRVLACNA--------GGPGEPAEVPGTVKVTEMLEYPDYELDERYQ 23838
Query: 1471 PAVTVRY---YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
+ VR R+T G P+ ++T G + + + + +T V RGDS
Sbjct: 23839 EGIFVRQGGVIRLTIPIKGKPFPICKWTKEG-QDISKRAMIATSETHTELVIKEADRGDS 23897
Query: 1528 ---------PASSKPISINYRTEIDKPSQ----MQVTDVQDNSISVKWLPSS----SPVT 1570
K + I R I P+ ++ D+Q S+ V W P + + +
Sbjct: 23898 GTYDLVLENKCGKKAVYIKVRV-IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADIL 23956
Query: 1571 GYRVTT--TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ-- 1626
GY + PK ++ G T + ++GL+ VEY V A+N G S+PL
Sbjct: 23957 GYILERREVPKAAWYTIDSRVRG---TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEE 24013
Query: 1627 --TAVTNIDRPKGLA----FTDVDVDSIKIAWESPQGQ-VSRYRVTYSSPEDGIHELFPA 1679
T T ++ P+ + DV S+ ++W P+ SR Y ++ + +
Sbjct: 24014 PVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVR 24073
Query: 1680 PDGEEDTAEL---QGLRPGSEYTVSVVALHD------DMESQPLIGTQSTAIPA-PTDLK 1729
+ + T + GL P +EY ++A +D S+P++ P+ P +L+
Sbjct: 24074 HNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELE 24133
Query: 1730 FTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVA 1785
++ S++ QW P ++ GY V + K + GL+ A
Sbjct: 24134 ILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEA 24193
Query: 1786 TKYEVSVYALKDTLTSRP---AQGVVTTL-ENVSPPRRARVTDAT 1826
T+YE V+A +T SRP A + T L +P R + D T
Sbjct: 24194 TEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVT 24238
Score = 148 bits (373), Expect = 7e-35
Identities = 289/1429 (20%), Positives = 524/1429 (36%), Gaps = 170/1429 (11%)
Query: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
D+T T+ ++ + + P S + ++ + ++SW + Y
Sbjct: 13060 DYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 13119
Query: 756 LSE-EGDEPQYLDLPSTA--TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQ 807
+ + E P + + +T TS ++ L+ G +Y N Y + + ++ +
Sbjct: 13120 VDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNP 13179
Query: 808 TTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNL-PETA 862
P P + + + V W P +PITGY + + + T++N P
Sbjct: 13180 YDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIE 13239
Query: 863 NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK 922
++ + LQ G +Y + A+ + P + P + + T
Sbjct: 13240 RTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSS 13299
Query: 923 VTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKV 977
V++ W P S + GY V+V + LP + + T EVTGL Y F+V
Sbjct: 13300 VSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRV 13359
Query: 978 FAVSHGRESKP-----------LTAQQTTKLDAPTNLQFVNETDST----VLVRWTPPRA 1022
+AV+ S P + +LDA + T V V+ PP
Sbjct: 13360 YAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPP-P 13418
Query: 1023 QITGYRLTVGLTRR-GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
+IT + V L R G + + + N A +Y ++L G +E V
Sbjct: 13419 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13478
Query: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDS 1135
T PG + E+++ + +TW P +P I + + R ++ T S
Sbjct: 13479 LDT--PGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECS 13536
Query: 1136 G-SIVVSGLTPGVEYVYTIQVLRD------GQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
S V+ L G Y + + + G+ RDA V TP P +L + + +
Sbjct: 13537 KTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDA--VKASQTP-GPVVDLKVRSVSKS 13593
Query: 1189 GVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
++ W++ + I GY + + N + V+ + + +L+ G EY
Sbjct: 13594 SC-SIGWKKPHSDGGSRIIGYVVDFLT----EENKWQRVMKSLSLQYSAKDLTEGKEYTF 13648
Query: 1246 SVYTVKDDKESVPISDTIIP---AVPPPTDLRFTNIGPDT-------------MRVTWAP 1289
V ++ E P T++ V P DL+ PD + + P
Sbjct: 13649 RVSAENENGEGTPSEITVVARDDVVAPDLDLKGL---PDLCYLAKENSNFRLKIPIKGKP 13705
Query: 1290 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL-------PGTEYVVSVSSVY 1342
PS+ S K E+ +A + +++ V T L+ +Y +++ +V
Sbjct: 13706 APSV---------SWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVA 13756
Query: 1343 EQHEST-PLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEH 1396
E T ++ K G+ PTG I F ++TA + T+ W P+ + IT Y I +
Sbjct: 13757 GTKEGTISIKVVGKPGI--PTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNY-ILEKRDS 13813
Query: 1397 FSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------GREESPLLIGQQSTVSDV 1450
+ + + + +T L G EY + A N G + P++ V D
Sbjct: 13814 VNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDA 13873
Query: 1451 PRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATIS 1506
P +V S+ ++W P T + Y + + E + P ++
Sbjct: 13874 PPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVT 13933
Query: 1507 GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP-- 1564
GL G++Y V A+ G S + ID P + +V ++ NS+++ W
Sbjct: 13934 GLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPK 13993
Query: 1565 --SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1622
+TGY V K + T+ L +Y + A+N +G
Sbjct: 13994 YDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAIS 14053
Query: 1623 PLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQV----------------SRYRVTY 1666
++ T I + + A T V +IK G S +
Sbjct: 14054 APSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGK 14113
Query: 1667 SSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT 1726
I ++ P T + + EYT++ + P P
Sbjct: 14114 DIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGP-PG 14172
Query: 1727 DLKFTQVTPTSLSAQWTPPNVQLTGYRVR--VTPKEKTGPMKEINLAPDSSSV--VVSGL 1782
++ + V+ + WTPP ++ G ++ + K +T + ++ D S V + L
Sbjct: 14173 PVEISNVSAEKATLTWTPP-LEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKL 14231
Query: 1783 MVATKYEVSVYALKDTLTSRPAQG----VVTTLENVSPPRRARVTDATETTITISWRTKT 1838
+ +Y V A+ P Q +V PP + V++ T+ T T+SW+
Sbjct: 14232 IQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPV 14291
Query: 1839 E----TITGFQVDAVPANGQTPIQRTIKPDVRSY--TITGLQPGTDYKIYLYTLN----- 1887
+ ITG+ V+ + R IK V +TGLQ G+ Y+ + N
Sbjct: 14292 DDGGSEITGYHVERREKKSLRWV-RAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 14350
Query: 1888 --DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPG 1941
A S ++ DA+ PSN TT S ++W P ITGY+++++K G
Sbjct: 14351 PPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVG 14410
Query: 1942 SPPREVVPRPRPG----VTEATITGLEPGTEYTIYVIALKNNQKSEPLI 1986
E + G +T+ + L+ +Y + A+ + EP +
Sbjct: 14411 D---EAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAV 14456
Score = 145 bits (367), Expect = 4e-34
Identities = 292/1351 (21%), Positives = 505/1351 (37%), Gaps = 184/1351 (13%)
Query: 780 LLPGRKYIVNVYQISEDG-----EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP 834
L+ +YI V +++ G E I++ + T P P P I+++W++P
Sbjct: 22899 LIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKP 22958
Query: 835 QAP----ITGYRIVYSPSVEGSSTELNLPETANSVTL--SDLQPGVQYNITIYAVEENQE 888
++ I+ Y + T +N L + L G Y + AV
Sbjct: 22959 ESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGN 23018
Query: 889 STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
S P + S T P + V+ T +++ WT P + + GY +++
Sbjct: 23019 SEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEK 23078
Query: 945 NLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA----QQTTKLDA 999
+ + + RNT V L G Y F+V AV+ S+ + + +++
Sbjct: 23079 DTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEI 23138
Query: 1000 PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP-----------RQYNVGPSV 1048
P +L+ ++ TV +R RL V ++ R P + +
Sbjct: 23139 P-DLELADDLKKTVTIRAG------ASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTT 23191
Query: 1049 SKYPLR-----NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI 1103
Y L N A +YT+ G + + V+ T P S+ EV+ ++
Sbjct: 23192 ESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKV--KEVSRDSV 23249
Query: 1104 VITWT------PAPRIGFKLGVRPSQGGEAPREVTSDSGSIV-VSGLTPGVEYVYTIQ-- 1154
ITW AP + + R + T S ++ +SGL G Y + +
Sbjct: 23250 TITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPE 23309
Query: 1155 ----VLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYR 1207
+ + DA +V++V PL P ++ T +T++WE+ +TGY
Sbjct: 23310 NIYGIGEPCETSDAVLVSEV--PLVPAKLEVVDVTKST--VTLAWEKPLYDGGSRLTGYV 23365
Query: 1208 ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY-----------------NVSVYTV 1250
+ ++ + + T +L+ G +Y V+ TV
Sbjct: 23366 LEACKAGTERWMKVV-TLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTV 23424
Query: 1251 KD-------DKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYS 1303
+D D ++P +PA P +L + + PPP+ F
Sbjct: 23425 QDLRVLPTIDLSTMPQKTIHVPA-GRPVEL--------VIPIAGRPPPAASW--FFAGSK 23473
Query: 1304 PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHESTPLRGRQKTGLDSPT 1362
++E E + + T + EY + + +V E+ + K G PT
Sbjct: 23474 LRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPG--PPT 23531
Query: 1363 G-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSG-RPREDRVPHSRNSITLT 1416
G I +I A S T+ W P A ++GY + H G P + V +R++ T
Sbjct: 23532 GPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESV--TRSTFKFT 23589
Query: 1417 NLTPGTEYVVSIVALN----GREESPLLIGQQSTVS--DVPRDLEVVAATPTSLLISWDA 1470
LT G EYV + A N G +I +S++ P L++ + + ++W
Sbjct: 23590 RLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYP 23649
Query: 1471 P----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD 1526
P V Y + E + V+ VP + + +GL G++Y V A+ RG
Sbjct: 23650 PEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGS 23709
Query: 1527 SPAS--SKPI-SINYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPK 1579
S SKPI +++ KP +VTD S+S+ W S VTGY +
Sbjct: 23710 GKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKV 23769
Query: 1580 NGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLA 1639
+ TK T E T+ L EY V A N G +P + L
Sbjct: 23770 DQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEM--LE 23827
Query: 1640 FTDVDVDS-IKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEY 1698
+ D ++D + QG V R + I + +G+ D ++ + +
Sbjct: 23828 YPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKW--TKEGQ-DISKRAMIATSETH 23884
Query: 1699 TVSVVALHDDMES------------QPLIGTQSTAIPAPTD----LKFTQVTPTSLSAQW 1742
T V+ D +S + + + I +P L++ + S+ W
Sbjct: 23885 TELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSW 23944
Query: 1743 TPP----NVQLTGYRV--RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1796
PP + GY + R PK I+ +S+VV GL +Y V A
Sbjct: 23945 RPPADDGGADILGYILERREVPK---AAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAEN 24001
Query: 1797 DTLTSRP--AQGVVTTLENVSPPRRA----RVTDATETTITISW-RTKTE---TITGFQV 1846
S+P ++ VT ++PP V D T++++++SW R K + +TG+ +
Sbjct: 24002 QFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYI 24061
Query: 1847 DAVPANGQTPIQRTIKPDVRS--YTITGLQPGTDYKIYLYTLND------NARSSPVVI- 1897
+ + ++ K + + YT+TGL P +Y+ + ND + S PVV
Sbjct: 24062 ERKETSTDKWVRHN-KTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCK 24120
Query: 1898 DASTAIDAPSNLRFLATTPNSLLVSWQPPRA----RITGYIIKYEKPGSPPREVVPRPRP 1953
D P L L+ + +S+ + W+ P I GY ++Y + G + + R
Sbjct: 24121 DPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERI 24180
Query: 1954 GVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
+ TI GL TEY V A S P
Sbjct: 24181 KDKQFTIGGLLEATEYEFRVFAENETGLSRP 24211
Score = 135 bits (339), Expect = 6e-31
Identities = 320/1486 (21%), Positives = 522/1486 (35%), Gaps = 215/1486 (14%)
Query: 771 TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVR 830
T S++ D KYI+ + S G +S ++ P P + V +V S +
Sbjct: 17773 TQLSIDNCDRNDAGKYILKLENSS--GSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLV 17830
Query: 831 WSRP----QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN 886
W P A + Y I S + ++ + S + +L G Y + A E
Sbjct: 17831 WEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEF 17890
Query: 887 QESTPVVIQQETTGTPRSDTVPSPRD-LQFVEVTDVKVTIMWTPPE----SAVTGYRVDV 941
PV ET ++ PSP + +V+ ++MW PE S V GY V++
Sbjct: 17891 GVGVPV----ETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEM 17946
Query: 942 IPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-----------LT 990
P E + S+ A VTGLS G Y F+V A + +S P LT
Sbjct: 17947 QPKGT--EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLT 18004
Query: 991 AQQTTKLDAPT-NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP----RQYNVG 1045
Q + KL T ++Q + + V P R + + G+P + NV
Sbjct: 18005 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRP--------RPNISWVKDGEPLKQTTRVNVE 18056
Query: 1046 PSVSKYPLR----NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN-TEVTE 1100
+ + L N +YTV+ G + + V +PG + P EV+
Sbjct: 18057 ETATSTVLHIKEGNKDDFGKYTVTATNSAGT--ATENLSVIVLEKPGPPVGPVRFDEVSA 18114
Query: 1101 TTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYV 1150
+VI+W P G G + S R+ T+ + +V ++ L G EY
Sbjct: 18115 DFVVISWEPPAYTG---GCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQ 18171
Query: 1151 YTIQVLRDGQERDAPIVNKVVTPLSP-----PTNLHLEANPDTGVLTVSWERSTTPD--- 1202
+ I + + AP+ +K V P P + + V W
Sbjct: 18172 FRI-FAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTK 18230
Query: 1203 ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN--VSVYTVKDDKESVPIS 1260
I GY + N L + D T L GLEY VS + + +S
Sbjct: 18231 IIGYHLEQKEKNSILWVKLNKTPIQDTKFKT-TGLDEGLEYEFKVSAENIVGIGKPSKVS 18289
Query: 1261 DTIIPAVP--PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELS 1315
+ + P PP I + + + W P +T ++V K+ D +
Sbjct: 18290 ECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEK---KDLPDGRWMK 18346
Query: 1316 ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFT 1375
S TN+L TE+ VS V +Q + R G S ITA
Sbjct: 18347 AS-------FTNVLE-TEFTVS-GLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARD-- 18395
Query: 1376 VHWIAPRATITG-YR---IRHHPEHF------SGRPREDRV--------------PHSRN 1411
AP A++ Y+ + H E F G+P D V ++
Sbjct: 18396 -EIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKS 18454
Query: 1412 SITLTNL-------TPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSL 1464
+I T L T G +Y++ + + G + P+ + L+V T
Sbjct: 18455 TIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKC 18514
Query: 1465 LISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
++W+ P + +Y I ET S Q T + + ++ L PG +Y V A
Sbjct: 18515 YLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYK-VTKLLPGNEYIFRVMA 18573
Query: 1521 VTGRG-DSPASSKPISI-NYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRV 1574
V G P S P++ N PS +V+ + +S+ V W + + GY +
Sbjct: 18574 VNKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYIL 18633
Query: 1575 TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT------- 1627
K G TK + + GL Y V A+N +G +P +
Sbjct: 18634 EKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACD 18693
Query: 1628 AVTNIDRPKGLAFTDVDVDSIKIAWESP----QGQVSRYRVTYSSPEDGIHELFPAPDGE 1683
A+ P TD S+ +AW P V Y V P G
Sbjct: 18694 ALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGL 18753
Query: 1684 EDTA-ELQGLRPGSEYTVSVVALHDDMESQPL-----IGTQSTAIPAPTDLKFTQVTPTS 1737
+ + L+ +EY + A++ + +P + Q P +L
Sbjct: 18754 QGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVV 18813
Query: 1738 LSAQWTPPNVQLTGYRVRVTPKEKTGPM----KEINLAPDSSSVVVSGLMV------ATK 1787
L A T R+ VT K + P K + D + + V+ T+
Sbjct: 18814 LRASAT--------LRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTR 18865
Query: 1788 YEVSVY--ALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETI 1841
++ Y L++ S+ A V L++ S P + + + ++T+SW I
Sbjct: 18866 FDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKI 18925
Query: 1842 TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1901
T + V+ + T ++ I LQ G Y + N+ P
Sbjct: 18926 TNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPV 18985
Query: 1902 AIDAP----SNLRFLATTPNSLLVSWQPPRA----RITGYIIKYEKPGSPPREVVPRPRP 1953
+ P + + T N+ + W+ P + +ITGY+++ + GS + +
Sbjct: 18986 KVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVK- 19044
Query: 1954 GVTEATITGLEPGTEYTIYVIALKNNQKSE------PLIGRKKTDELPQLVTLPHP--NL 2005
EATI+GL G EY V A+ +S+ P+I R E+ V LP N+
Sbjct: 19045 -TLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIAR--DIEIKPSVELPFHTFNV 19101
Query: 2006 HGPEIL--DVP---------------STVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQ 2048
E L DVP T+++T V T + + S + VG
Sbjct: 19102 KAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEAS--KEDVGT 19159
Query: 2049 QMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAP 2094
+ + T P T + P P + + + TISW P
Sbjct: 19160 YELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNP 19205
Score = 133 bits (334), Expect = 2e-30
Identities = 288/1457 (19%), Positives = 519/1457 (35%), Gaps = 224/1457 (15%)
Query: 728 VTEITASSFVVSWVSASDTVSGFRVEY--ELSEEGDEP-QYLDLPSTATSVNIPDLLPGR 784
V+ ++A S V+SW D Y E E G Q ++ T + + L
Sbjct: 22445 VSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYM 22504
Query: 785 KYIVNV-----YQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPIT 839
+Y V + +S+ E + I++ P AP P V V ++ +RW P
Sbjct: 22505 EYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGG 22564
Query: 840 GYRIVYSPSVEGSST-----ELNLPETANSVTLSDLQPGVQYNITIYAV------EENQE 888
I Y + +T E +P + ++ L G++Y YA+ + ++
Sbjct: 22565 SKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEA 22624
Query: 889 STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
S P++ Q + V +P + +VT V+++W+ P S V GY ++ PV
Sbjct: 22625 SRPIMAQ---------NPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPV 22675
Query: 945 NLPGEHGQRLP----ISRNTFAEVTGLSPGVTYYFKVFA------VSHGRESK-PLT--- 990
+ G+ G+ L I + F VT LS G TY F+V A +S G ES P+T
Sbjct: 22676 SEVGD-GRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRD 22734
Query: 991 --AQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR-------- 1040
A +LDA + V + LV A + G + +G
Sbjct: 22735 EYAPPKAELDARLHGDLVTIRAGSDLVL----DAAVGGKPEPKIIWTKGDKELDLCEKVS 22790
Query: 1041 -QYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTL--QPGSSIPPYNTE 1097
QY + + + + +YT+++ N KA V + PG +
Sbjct: 22791 LQYTGKRATAVIKFCDRSDSGKYTLTVK----NASGTKAVSVMVKVLDSPGPCGKLTVSR 22846
Query: 1098 VTETTIVITWTPAPRIGFKLGVRPSQGGEAP-------REVTSDSGSIVVSGLTPGVEYV 1150
VT+ + W+ P + G A R TS ++V G P + YV
Sbjct: 22847 VTQEKCTLAWS-----------LPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYV 22895
Query: 1151 YTIQVLRDGQE----------------RDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVS 1194
T +++++ + PIV + + P + E + +
Sbjct: 22896 VT-RLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQ 22954
Query: 1195 WERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK 1251
W + + +I+ Y + + + + + +L G +Y V V
Sbjct: 22955 WTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVN 23014
Query: 1252 DDKESVP--ISDTIIPAVP-----PPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSP 1304
S P S+ I P PP+ R + ++ + W P D +V Y
Sbjct: 23015 AAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKP-MYDGGTDIVGYVL 23073
Query: 1305 VKNEEDVAE-----LSISPSDNAVVLTNLLPGTEYVVSVSSV----YEQHESTPLRGRQK 1355
E+D + + + + + +L G +Y V++V ++ +
Sbjct: 23074 EMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPV 23133
Query: 1356 TGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP-------- 1407
++ P ++ +D + T+ A + R P + D
Sbjct: 23134 ERIEIPD-LELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTE 23192
Query: 1408 -HSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLI 1466
+S + N +Y + +G++ + +L+ T P ++V + S+ I
Sbjct: 23193 SYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCP-SVKVKEVSRDSVTI 23251
Query: 1467 SWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA-- 1520
+W+ P + V Y + E + + T SK+ ISGL G Y V
Sbjct: 23252 TWEIPTIDGGAPVNNYIVEKREAAMRA-FKTVTTKCSKTLYRISGLVEGTMYYFRVLPEN 23310
Query: 1521 VTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTT 1576
+ G G+ +S + ++ + P++++V DV +++++ W S +TGY +
Sbjct: 23311 IYGIGEPCETSDAVLVSEVPLV--PAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEA 23368
Query: 1577 TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPK 1636
K T P E T+ L +Y+ + AQN G S+P + +
Sbjct: 23369 CKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLR 23428
Query: 1637 GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDG--EEDTAELQGLRP 1694
L D+ K P G+ + + F A E + ++
Sbjct: 23429 VLPTIDLSTMPQKTI-HVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTK 23487
Query: 1695 GSEYTVSVVALHDD----MESQPLIGTQSTAI---------PAPTDLKFTQVTPTSLSAQ 1741
++ T+ + D +E + + GT S I P +K ++ TS++
Sbjct: 23488 VAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITIS 23547
Query: 1742 WTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1797
W PP + L+GY V + G + P S SV S E + Y +
Sbjct: 23548 WEPPELDGGAPLSGYVVEQRDAHRPGWL------PVSESVTRSTFKFTRLTEGNEYVFRV 23601
Query: 1798 TLTSRPAQGVVTTLENVS---------PPRRARVTDATETTITISWRTKTET----ITGF 1844
T+R G E + PP ++ D + +T++W + +TG+
Sbjct: 23602 AATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGY 23661
Query: 1845 QVDAVPANGQTPIQRTIKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSP-------VV 1896
V+ ++ P + Y TGL G +Y+ + +N P V
Sbjct: 23662 IVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVA 23721
Query: 1897 IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPR 1952
+D P N R TT S+ ++W P +++TGY+I+ +K
Sbjct: 23722 MDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTP 23781
Query: 1953 PGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILD 2012
+ E T+T L G EY V+A EP +
Sbjct: 23782 TKIREYTLTHLPQGAEYRFRVLACNAGGPGEP--------------------------AE 23815
Query: 2013 VPSTVQKTPFVTHPGYD 2029
VP TV+ T + +P Y+
Sbjct: 23816 VPGTVKVTEMLEYPDYE 23832
Score = 132 bits (332), Expect = 4e-30
Identities = 282/1282 (21%), Positives = 484/1282 (37%), Gaps = 198/1282 (15%)
Query: 611 PVEVFITETPSQPNSHPIQWNAP---QPSHISKYILRWRPKNSVGRWKEATIPGHLNSYT 667
PV V + E +S + W P S I Y+++ R W T S+
Sbjct: 13485 PVNVTVKEISK--DSAYVTWEPPIIDGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFR 13541
Query: 668 IKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSES 727
+ L+ G Y ++ + +YG + T + V TP P+V
Sbjct: 13542 VANLEEGKSYFFRVFAENEYGIGDPGE------------TRDAVKASQTP-GPVVDLK-- 13586
Query: 728 VTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
V ++ SS + W + G+ V++ L+EE + + S + + DL G
Sbjct: 13587 VRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMK--SLSLQYSAKDLTEG 13643
Query: 784 RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITG 840
++Y V +E+GE + T PD + + D + + + R + PI G
Sbjct: 13644 KEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKG 13703
Query: 841 YRIVYSPSVE--------GSSTELNLPETANSVTLS--DLQPGV--QYNITIYAVEENQE 888
+PSV + T +++ +A + TL D Q +Y IT+ V +E
Sbjct: 13704 KP---APSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13760
Query: 889 STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
T I + G P T P ++F EVT +T+ W PP+ S +T Y ++
Sbjct: 13761 GT---ISIKVVGKPGIPTGP----IKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDS 13813
Query: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKL-D 998
+ + TF VT L G+ Y F+V + V G +S+P+ A+ + D
Sbjct: 13814 VNNKWVTCASAVQKTTF-RVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPD 13872
Query: 999 APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP-SVSKYPL 1053
AP V+ +V + WT P+ + ITGY L ++ N P + + +
Sbjct: 13873 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV 13932
Query: 1054 RNLQPASEYTVSLVAIK----GNQESPKATGVFTTLQPGSSIPPYNTEV---TETTIVIT 1106
L EY ++AI G P V L P PP EV T ++ +
Sbjct: 13933 TGLTEGLEYEFRVMAINLAGVGKPSLPSEPVV--ALDPID--PPGKPEVINITRNSVTLI 13988
Query: 1107 WT-PAPRIGFKLGVR-------PSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD 1158
WT P G KL PS+ V + V+ L G +Y + I+
Sbjct: 13989 WTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNT 14048
Query: 1159 GQERDAPIVN----------KVVTPLSPPT---NLHLEANPDTGVLTV-----------S 1194
AP + + T + PT L ++A DT VL S
Sbjct: 14049 AGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAG-DTIVLNAISILGKPLPKSS 14107
Query: 1195 WERS----TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
W ++ DIT +IT+TPT+ +++ D T +P + V V
Sbjct: 14108 WSKAGKDIRPSDIT--QITSTPTSSML--TIKYATRKDAGEYTITATNP---FGTKVEHV 14160
Query: 1251 KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEED 1310
K T++ PP + +N+ + +TW PP D + + Y K E
Sbjct: 14161 KV---------TVLDVPGPPGPVEISNVSAEKATLTWTPPLE-DGGSPIKSYILEKRETS 14210
Query: 1311 VAELSISPSDNAV---VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD------SP 1361
++ D V T L+ G EY+ VS+V + P++ +D P
Sbjct: 14211 RLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPP 14270
Query: 1362 TGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
+ S++T N+ TV W P + ITGY + + R + P S +T
Sbjct: 14271 EKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTG 14330
Query: 1418 LTPGTEYVVSIVALNGREESP-------LLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
L G+ Y + A N P +L+ + P + V T S ++W
Sbjct: 14331 LQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGK 14390
Query: 1471 P----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKPGVDYTITVYAVTGRG 1525
P + + Y + + + G + +++ T + T + L+ Y + A+ G
Sbjct: 14391 PHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAG 14450
Query: 1526 -DSPASSKPISINYR---TEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNG 1581
PA + I R + + ++++ T V +S++ VT T N
Sbjct: 14451 VGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNI 14510
Query: 1582 PGPTKTKTAGPDQTEMTIE---GLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRP-KG 1637
+ + + I T ++V+++ +NP+G+ V V + P
Sbjct: 14511 NLKNRANIENTESFTLLIIPECNRYDTGKFVMTI--ENPAGKKSGFVNVRVLDTPGPVLN 14568
Query: 1638 LAFTDVDVDSIKIAWESP----QGQVSRY--------RVTYSSPEDGIHELFPAPDGEED 1685
L TD+ DS+ + W+ P +++ Y R +YS+ H+
Sbjct: 14569 LRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKC--------- 14619
Query: 1686 TAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ---STAIPAPTD-LKFTQVTPTSLSAQ 1741
T ++ GL G EY V+A ++ +P T+ ++ P+P D L +T +++S
Sbjct: 14620 TYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLA 14679
Query: 1742 WTPP----NVQLTGYRVRVTPK 1759
W P ++TGY + K
Sbjct: 14680 WPKPKHDGGSKITGYVIEAQRK 14701
Score = 129 bits (324), Expect = 3e-29
Identities = 296/1415 (20%), Positives = 523/1415 (36%), Gaps = 202/1415 (14%)
Query: 728 VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT----SVNIPDLLPG 783
+ ++++ V W D G ++ + E+ + + + +AT + L+ G
Sbjct: 12000 IVDVSSDRCTVCWDPPEDD-GGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEG 12058
Query: 784 RKYIVNVYQISEDG-----EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ--- 835
+YI V ++ G E +++ ++ P P P V +V + V W+ P+
Sbjct: 12059 NEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDG 12118
Query: 836 -APITGYRIVYSPSVEGSSTELN---LPETANSVTLSDLQPGVQYNITIYAVEENQESTP 891
ITGY + +N +PE V +L P +Y + A E P
Sbjct: 12119 GKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKV--QNLLPDHEYQFRVKAENEIGIGEP 12176
Query: 892 VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNL- 946
+ + + P + + V+ T +T+ W P + + GY V++ P
Sbjct: 12177 SLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIAD 12236
Query: 947 --PGEHGQRL----PISRNTFAEVTGLSPGVTYYFKVFA---VSHGRESKPLTAQQTTKL 997
P E +R + R F VT L Y F+V A V GR ++ A + ++
Sbjct: 12237 ASPDEGWKRCNAAAQLVRKEFT-VTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEI 12295
Query: 998 DAPTNLQFVNETDSTVLVRWT-----------PPRAQITGYRLTV-GLTRRGQPRQYNVG 1045
P + V+VR P ++T ++ + + R+GQ +
Sbjct: 12296 LEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDT- 12354
Query: 1046 PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105
+ P + +Y+++LV G + V T P S + ++VT+T+ +
Sbjct: 12355 MAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKV--SDVTKTSCHV 12412
Query: 1106 TWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQV 1155
+W P G G + + RE + S V V+ L PG EY + +
Sbjct: 12413 SWAPPENDG---GSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTA 12469
Query: 1156 LRD---GQERDAPIVNKVVTPLS---PPTNLHLEANPDTGVLTVSWE---RSTTPDITGY 1206
+ + G D P PLS PP L + T++W R I GY
Sbjct: 12470 VNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSA-TLAWLPPLRDGGAKIDGY 12528
Query: 1207 RITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKESVPISD 1261
IT+ Q + E S L G +Y V V +E+ + +
Sbjct: 12529 -ITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYE 12587
Query: 1262 TIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK---NEEDV---AELS 1315
+PP + P+ + + I+ + + K E++V + L+
Sbjct: 12588 AKEQLLPPKI------LMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLA 12641
Query: 1316 ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP----TGIDFSDITA 1371
+ +D++ +L + S E T + + +D+P D SDI A
Sbjct: 12642 VHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDA 12701
Query: 1372 NSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH----SRNSITLTNLTPGTEYVVS 1427
++ ++ W P G I ++ R D V ++ S + L PG EY+
Sbjct: 12702 DACSLSWHIPLED-GGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFR 12760
Query: 1428 IVALN--GREE---SPLLIGQ-QSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRIT 1481
+ A N G E SP ++ Q V P++ V + ++WD P
Sbjct: 12761 VRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRP---------- 12810
Query: 1482 YGETGGNSPVQEFTVPGSKSTATI----------------SGLKPGVDYTITVYAVTGRG 1525
++ G SP+ + + + + + +GL G++Y+ +YA+ G
Sbjct: 12811 --DSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAG 12868
Query: 1526 DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPKNG 1581
SP S + R +D P + +V DV +++S+ W S + GY V G
Sbjct: 12869 SSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPG 12928
Query: 1582 PGPTKTKTAGPD--QTEMTIEGLQPTVEYVVSVYAQN------PSGESQP---LVQTAVT 1630
+ TA Q E T GL+ +Y A+ PS S P L +
Sbjct: 12929 DKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPP 12988
Query: 1631 NIDRPKGL-------AFTDVDVDSIKIAWESPQGQVS-RYRVTYSSPEDGIHELFPAPDG 1682
ID + A T+V +D+ + P VS + T P +GI A
Sbjct: 12989 RIDLSVAMKSLLTVKAGTNVCLDA--TVFGKPMPTVSWKKDGTLLKPAEGIK---MAMQR 13043
Query: 1683 EEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQ 1741
T EL + ++ A + I + P P +K ++
Sbjct: 13044 NLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLS 13103
Query: 1742 WTPP----NVQLTGYRVRVTPKEKTGP-MKEINLAPDSSSVVVSGLMVATKYEVSV---- 1792
W PP ++T Y V +E + P +++ +S V L+ +Y+ +
Sbjct: 13104 WEPPLEDGGSEITNY--IVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAEN 13161
Query: 1793 -YALKDTLTSRPAQGVVTTLENVSPPRRAR---VTDATETTITISWRTKTE----TITGF 1844
Y + D + + PA PP R +++ T+ +T+SW+ + ITG+
Sbjct: 13162 KYGVGDPVFTEPA----IAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGY 13217
Query: 1845 QVDAVPANGQTPIQRTIKPDV-RSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI 1903
++ + KP + R+ TGLQ GT+Y+ + +N P DAS A
Sbjct: 13218 LLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKP--SDASKAA 13275
Query: 1904 DA---------PSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPR 1950
A P+ + TT +S+ +SW P + I GY+++ ++ S
Sbjct: 13276 YARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNL 13335
Query: 1951 PRP-GVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
P+ T +TGL T+Y V A+ S+P
Sbjct: 13336 PQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDP 13370
Score = 123 bits (309), Expect = 2e-27
Identities = 282/1358 (20%), Positives = 482/1358 (35%), Gaps = 200/1358 (14%)
Query: 780 LLPGRKYIVNVYQISEDGE----QSLILSTSQTTAPDAPPD-PTVDQVDDTSIVVRWSRP 834
L+ G +YI V ++ G+ QS + P PP+ P V V + V W RP
Sbjct: 14231 LIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRP 14290
Query: 835 Q----APITGYRIVYSPSVEGSSTE-LNLPETANSVTLSDLQPGVQYNITIYA-----VE 884
+ ITGY + + P + ++ LQ G Y + A +
Sbjct: 14291 VDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 14350
Query: 885 ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVD 940
E++ V+ ++ P + P D T ++ W P +TGY V+
Sbjct: 14351 PPSEASDSVLMKDAAYPPGPPSNPHVTD-----TTKKSASLAWGKPHYDGGLEITGYVVE 14405
Query: 941 VIPVN----LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ--QT 994
V + G L I++ V L Y F++ A++ +P +
Sbjct: 14406 HQKVGDEAWIKDTTGTALRITQFV---VPDLQTKEKYNFRISAINDAGVGEPAVIPDVEI 14462
Query: 995 TKLDAPTNLQFVNETDSTVLVR-------WTP----PRAQITGYRLTVGLTRRGQPRQYN 1043
+ + + + E T++VR + P P ++T + + L R
Sbjct: 14463 VEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTE 14522
Query: 1044 VGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI 1103
++ P N ++ +++ G + V T P ++ P T++T+ ++
Sbjct: 14523 -SFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRP--TDITKDSV 14579
Query: 1104 VITWT-PAPRIGFKLGVRPSQGGEAPREVTSDSGS------IVVSGLTPGVEYVYTIQVL 1156
+ W P G ++ + EA R+ S + + V+GL+ G EY + +
Sbjct: 14580 TLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAE 14639
Query: 1157 RD---GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITT 1210
+ G+ + K SPP +L++ + ++++W + ITGY I
Sbjct: 14640 NEYGIGEPTETTEPVKASEAPSPPDSLNI-MDITKSTVSLAWPKPKHDGGSKITGYVIEA 14698
Query: 1211 TPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTII----PA 1266
Q + V + C NL+ G EY V V S P +
Sbjct: 14699 QRKGSDQWTHITTVKGLE---CVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQT 14755
Query: 1267 VPPPTDLR-------FTNIGPDT---MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316
+ P DLR G + + V P P++ K + + + +
Sbjct: 14756 MLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTW----------KKGDQILKQTQ 14805
Query: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL-------------DSPTG 1363
+ + +L E V S S Y PL R G PTG
Sbjct: 14806 RVNFETTATSTILNINECVRSDSGPY------PLTARNIVGEVGDVITIQVHDIPGPPTG 14859
Query: 1364 -IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNL 1418
I F +++++ T W P I+ Y + S E R + T L
Sbjct: 14860 PIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTD-STTWVELATTVIRTTYKATRL 14918
Query: 1419 TPGTEYVVSIVALN------GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP- 1471
T G EY + A N G + ++ V P +V A T S+ ISW P
Sbjct: 14919 TTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPL 14978
Query: 1472 ---AVTVRYYRITYGETGGN--SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD 1526
+ Y + E G V + VPG+ + SGL G+ Y V A G
Sbjct: 14979 SDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKS--SGLTDGIAYEFRVIAENMAGK 15036
Query: 1527 SPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGP 1582
S S + ID P + ++ +++++KW +T Y V
Sbjct: 15037 SKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNG 15096
Query: 1583 GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ--TAVTNIDRPKGLAF 1640
K + + E T+ GL Y V A+N +G P + A+T D
Sbjct: 15097 RWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRD------- 15149
Query: 1641 TDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGL-------- 1692
DV+ IK+ + + + + D P + +D EL+G
Sbjct: 15150 -DVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIA 15208
Query: 1693 -------------RPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTD--LKFTQVTPTS 1737
R YT++ A + ++ + + P P + L T+VT
Sbjct: 15209 DFSTNLVNKDSTRRDSGAYTLT--ATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEK 15266
Query: 1738 LSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKY--- 1788
W PP ++ Y + K +T + N+A + + + V+ L+ +Y
Sbjct: 15267 CVLSWFPPLDDGGAKIDHY---IVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFR 15323
Query: 1789 --EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISW----RTKTETIT 1842
V+ Y + + L S P V PP+ VT T+ ++ + W I
Sbjct: 15324 VMAVNKYGVGEPLESEPVL-AVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEII 15382
Query: 1843 GFQVDAVPANGQTPIQRTIK--PDVRSYTITGLQPGTDYKIYLYTLNDNARSSP------ 1894
+ V+ GQ I+ K D+R Y ++GL G +Y+ + N S+P
Sbjct: 15383 NYIVERRDKAGQRWIKCNKKTLTDLR-YKVSGLTEGHEYEFRIMAENAAGISAPSPTSPF 15441
Query: 1895 -VVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVP 1949
D P N R L T+ +S+ ++W P + ITGY+++ P ++V
Sbjct: 15442 YKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVT 15501
Query: 1950 RPRP-GVTEATITGLEPGTEYTIYVIALKNNQKSEPLI 1986
P T TITGL EY I + A+ + EP +
Sbjct: 15502 PPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPAL 15539
Score = 121 bits (303), Expect = 9e-27
Identities = 287/1414 (20%), Positives = 508/1414 (35%), Gaps = 177/1414 (12%)
Query: 610 GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
GP E + T + WN P ++IS YI+ R + + W + + +Y
Sbjct: 18498 GPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLS-WTQVSTEVQALNY 18556
Query: 667 TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
+ L PG Y +++++ +YG E P+ S VT P ++
Sbjct: 18557 KVTKLLPGNEYIFRVMAVNKYGIGE-------------PLESGPVTACNPYKPPGPPSTP 18603
Query: 727 SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEP-----QYLDLPSTATSVNIPDLL 781
V+ IT S VV+W D G +E + E+ D+ + T + + L
Sbjct: 18604 EVSAITKDSMVVTWARPVDD-GGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLT 18662
Query: 782 PGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPP-DPTVDQVDDTSIVVRWSRP- 834
G Y N + E E S+ P PP +P V +S+ + WS+P
Sbjct: 18663 EGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPI 18722
Query: 835 ---QAPITGYRIVYSPSVEGSSTELNLPE--TANSVTLSDLQPGVQYNITIYAVEENQES 889
AP+ GY + + T P T++ L+ +YN I A+
Sbjct: 18723 YDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVG 18782
Query: 890 TPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK--------VTIMWTP-PE---SAVTGY 937
P + R + D +V ++ VTI P PE G
Sbjct: 18783 EPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGI 18842
Query: 938 RVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL 997
D + + + VT G Y + G ++ + +
Sbjct: 18843 LTDRAQIEVTSS------FTMLVIDNVTRFDSG--RYNLTLENNSGSKTAFVNVRVLDSP 18894
Query: 998 DAPTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPL 1053
AP NL +V + W PP A+IT Y + T R + + + +
Sbjct: 18895 SAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRI 18954
Query: 1054 RNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN------TEVTETTIVITW 1107
NLQ Y ++A + E TT S PP +VT T I W
Sbjct: 18955 ENLQEGCSYYFRVLA---SNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKW 19011
Query: 1108 T-PAPRIGFKLG----VRPSQGGEAPREVTS-DSGSIVVSGLTPGVEYVYTIQVLR---- 1157
P G K+ ++G E T + +SGLT G EYV+ + +
Sbjct: 19012 EKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGR 19071
Query: 1158 -DGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGY-RITTTPTNG 1215
D ++ P++ + + + P L V D+ R T
Sbjct: 19072 SDPRQLGVPVIARDIE-IKPSVELPFHT------FNVKAREQLKIDVPFKGRPQATVNWR 19124
Query: 1216 QQGNSLEEVVHADQSSC---TFDNLSPGLEYNVSVYTVKDDKES----VPISDTIIPAVP 1268
+ G +L+E + SS T ++ + +V Y + + VPI+ ++
Sbjct: 19125 KDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPG 19184
Query: 1269 PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAE---LSISPSDNA 1322
PP +R + D++ ++W PP ++N++V K E +S + + +
Sbjct: 19185 PPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVE----KKETTSTTWHIVSQAVARTS 19240
Query: 1323 VVLTNLLPGTEYVVSVSS-----VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTV 1376
+ + L G+EY V + ES+ + P G T ++ V
Sbjct: 19241 IKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLV 19300
Query: 1377 HWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN 1432
W P + + GY + + + +++ + + ++ L G Y + A N
Sbjct: 19301 TWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAEN 19360
Query: 1433 ----GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGE 1484
G+ D P EV T S+ + W P + Y + E
Sbjct: 19361 IAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRE 19420
Query: 1485 TGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEID 1543
++ ++ ++ L Y V+A S S I + +++
Sbjct: 19421 LPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVE 19480
Query: 1544 KPSQMQVTDVQDNSI--SVKWLPSSSPVTG--YRVTTTPKNG---PGPTKTKTAGPD-QT 1595
P M +D + + + L ++ + G V + K+G +T+ D T
Sbjct: 19481 PPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHT 19540
Query: 1596 EMTIEGL--QPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKG--LAFTDVDVDSIKIA 1651
+T++ + T +YV+++ +N +G V V + P L + + ++
Sbjct: 19541 LLTVKDCIRRDTGQYVLTL--KNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLS 19598
Query: 1652 WESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGE--EDTAELQGLRPGSEYTVSVVAL 1705
W PQ + Y V + H + +GE + ++ L G+EY V +
Sbjct: 19599 WGRPQEDGGADIDYYIV---EKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGV 19655
Query: 1706 HDDMESQPLIGTQSTAIPA---------PTDLKFTQVTPTSLSAQWTPP----NVQLTGY 1752
+ +PL +S AI A PT L+ T VT S++ W+ P +++GY
Sbjct: 19656 NKYGVGEPL---ESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGY 19712
Query: 1753 RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTT 1810
+ K ++ V +GL +YE VYA S P++ ++
Sbjct: 19713 IIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRA 19772
Query: 1811 LENV---SPPRRARVTDATETTITISWRTKT----ETITGFQVD---AVPANGQTPIQRT 1860
+ V SPP + ++ D+ +TTITI+W ITG+ V+ + + +T IQ
Sbjct: 19773 EDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSL 19832
Query: 1861 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP 1894
+ YTI+GL G +Y + ++N S P
Sbjct: 19833 RGTE---YTISGLTTGAEYVFRVKSVNKVGASDP 19863
Score = 120 bits (302), Expect = 1e-26
Identities = 326/1553 (20%), Positives = 547/1553 (35%), Gaps = 248/1553 (15%)
Query: 605 YPSSSGPVEVFITETPSQPNSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEA-TIP 660
Y P+ V IT+ S + W P+ + I+ Y++ R K S+ RW A T+
Sbjct: 6883 YDVPGPPLNVTITDVNRFGVS--LTWEPPEYDGGAEITNYVIELRDKTSI-RWDTAMTVR 6939
Query: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
S T+ V EGQ S + R S +TP E P P
Sbjct: 6940 AEDLSATVTD-----VVEGQEYSFRVRAQN---RIGVGKPSAATPFVKVADPIER-PSPP 6990
Query: 721 LVATSESVTEITASSFVVSWV----SASDTVSGFRVEYELSEEGDEPQY---LDLPSTAT 773
+ TS T+ SS + W + G+ +E EEG + + L T
Sbjct: 6991 VNLTSSDQTQ---SSVQLKWEPPLKDGGSPILGYIIER--CEEGKDNWIRCNMKLVPELT 7045
Query: 774 SVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV---DDTSIVVR 830
+ L G KY+ V ++ G TA DA +PT+D D ++V
Sbjct: 7046 -YKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIV- 7103
Query: 831 WSRP---QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSD-----LQPGVQYNITIYA 882
P P TGY + G L + TLS + P + + IY
Sbjct: 7104 -PNPITILVPSTGYPRPTATWCFGDKV-LETGDRVKMKTLSAYAELVISPSERSDKGIYT 7161
Query: 883 VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYR 938
++ + + + R +P++L+F ++T V + W PP+ S +TGY
Sbjct: 7162 LKLENRVKTISGEIDVNVIARPS---APKELKFGDITKDSVHLTWEPPDDDGGSPLTGYV 7218
Query: 939 VDVIPVNLPGEHGQRLPISRNTFAE-----------VTGLSPGVTYYFKVFAVSHGRESK 987
V ++ +SR T+ + V L G Y FKV A + +
Sbjct: 7219 V------------EKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGE 7266
Query: 988 PLTAQQTTKL-------DAPTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRR 1036
P + + D P N+++ + T +++ + W PP+ ++I GY V R
Sbjct: 7267 PAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGY--IVERCPR 7324
Query: 1037 GQPRQYNVGPSV--SKYPLRNLQPASEYTVSLVAIK-----------------GNQESPK 1077
G + G V +K + L+ Y + A+ QE+P+
Sbjct: 7325 GSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPE 7384
Query: 1078 ATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGF-KLGVRPSQGGEAPREVTSDSG 1136
+F ++ + + E +T P P+I + K + Q E
Sbjct: 7385 ---IFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKS 7441
Query: 1137 SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHL-EANPDTGVLTVSW 1195
++ + Y I+ + A + V+ PP + + ++ +LT +
Sbjct: 7442 TVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNP 7501
Query: 1196 ERST-TPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV-----YT 1249
R IT Y + T+ + + L V T L P EY V Y
Sbjct: 7502 PRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKAT--KLIPNKEYIFRVAAENMYG 7559
Query: 1250 VKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPV 1305
V + ++ PI+ P PPT L ++I D + +TW P +T + V
Sbjct: 7560 VGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDP 7619
Query: 1306 KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGID 1365
++ V + D + L +Y V + P + + + P
Sbjct: 7620 DTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPP 7679
Query: 1366 F-------SDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPR-EDRVPHSRNSI 1413
+ D+ S ++W P A I Y I R + VP +++
Sbjct: 7680 WPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH-- 7737
Query: 1414 TLTNLTPGTEYVVSIVALNGREES-------PLLIGQQSTVSDVPRDLEVVAATPTSLLI 1466
L L G EY + A+N ES P+L ++ PR LEV+ T + +
Sbjct: 7738 LLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADL 7797
Query: 1467 SWDAPAVTVRYYRITYGETGGNSPVQEFTVPG---------------SKSTATISGLKPG 1511
W P E G SP+ + V + T++ L G
Sbjct: 7798 KWTVP------------EKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEG 7845
Query: 1512 VDYTITVYAVTGRGDSPASSKPISINYR---TEIDKPSQMQVTDVQDNSISVKWLPSSS- 1567
Y V A G S + S+ + T P + V DV + +KW P +
Sbjct: 7846 SLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKND 7905
Query: 1568 ---PVTGYRVTTTPKNGPGPTKT-KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
P+ Y + + G K KTAGPD + ++ T E V A+N +G P
Sbjct: 7906 GGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGT-EVQFQVRAENEAGVGHP 7964
Query: 1624 LVQTAVTNIDRPKG-------LAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHEL 1676
T + +I+ P L TD I IAW+ P+ SP G H +
Sbjct: 7965 SEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPE-------KNGGSPIIGYH-V 8016
Query: 1677 FPAPDGEEDTAEL-------------QGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP 1723
P G E + +G+ P EY + V A++ S+P +++
Sbjct: 8017 EMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAK 8076
Query: 1724 APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLM 1783
P D K T T + + G ++ + + P+ ++ D V S +
Sbjct: 8077 DP-DCKPTIDLETH-------DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRL 8128
Query: 1784 VATKYEVSVYALKDTLTSRPAQGVVT-TLEN----------------VSPPRRARVTDAT 1826
+S + L+ + R G+ T TLEN P + + +D T
Sbjct: 8129 TMKNDHISAH-LEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDIT 8187
Query: 1827 ETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIY 1882
+++ ++W I + ++ A +T I + S+T+ L P +Y
Sbjct: 8188 KSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFR 8247
Query: 1883 LYTLND-------NARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARIT 1931
+ +N ++ + D D P ++ T ++ ++W+PP ++I
Sbjct: 8248 VKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIM 8307
Query: 1932 GYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
GYII+ G + + T GLE G EY V A SEP
Sbjct: 8308 GYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEP 8360
Score = 118 bits (296), Expect = 6e-26
Identities = 316/1543 (20%), Positives = 554/1543 (35%), Gaps = 238/1543 (15%)
Query: 607 SSSGPVEVFIT----ETPSQPNSHPIQWNAPQPSHISKYILRWRP---------KNSVGR 653
+SSG F+T +TP P + ++ + L W P KN V
Sbjct: 17794 NSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSA-----FLVWEPPIIDGGAKVKNYVID 17848
Query: 654 WKEATIPGHLN--------SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTP 705
+E+T + N S+ ++ L G +Y ++++ ++G P
Sbjct: 17849 KRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG-------------VGVP 17895
Query: 706 VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGD 761
V + P SP ++T+++ +S + W V G+ VE + +G
Sbjct: 17896 VETVDAVKAAEPPSP--PGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE--MQPKGT 17951
Query: 762 EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQ 821
E + S + + L G++Y V +E G+ + A D P++
Sbjct: 17952 EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKL 18011
Query: 822 VDDTSIVVRWS--RPQAPITGY-RIVYSPSVEGS----STELNLPETANSVTLSDLQPGV 874
+T + + + P+ G R S +G +T +N+ ETA S L ++ G
Sbjct: 18012 PFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLH-IKEGN 18070
Query: 875 QYNITIYAVEENQESTPV-----VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTP 929
+ + Y V + VI E G P ++F EV+ V I W P
Sbjct: 18071 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGP-------VRFDEVSADFVVISWEP 18123
Query: 930 PESA----VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE 985
P ++ Y V+ H ++R T ++T L G Y F++FA + +
Sbjct: 18124 PAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTI-KITKLKTGTEYQFRIFAENRYGK 18182
Query: 986 SKPLTA-----QQTTKLDAPTNLQFVNE-TDSTVLVRWTPP----RAQITGYRLTVGLTR 1035
S PL + Q K P FV + +LV+W P +I GY L
Sbjct: 18183 SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 18242
Query: 1036 RGQPRQYNVGP-SVSKYPLRNLQPASEYT--VSLVAIKGNQESPKATGVFTTLQPGSSIP 1092
+ N P +K+ L EY VS I G + K + F P P
Sbjct: 18243 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCD--P 18300
Query: 1093 PYNTE---VTETTIVITWT-PAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
P E +T + + W PA G K+ + + P G + + T +E
Sbjct: 18301 PGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLP------DGRWMKASFTNVLE 18354
Query: 1149 YVYTIQVLRDGQERDAPIVNK-VVTPLSPPT---------------NLHLEANPDTGVLT 1192
+T+ L + Q + ++ + S P+ N L+ ++
Sbjct: 18355 TEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVV 18414
Query: 1193 VSWERSTTP-DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLS---------PGLE 1242
+ E DI G I + + G LEE + T + G +
Sbjct: 18415 HAGETFVLEADIRGKPIPDVVWS-KDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18473
Query: 1243 YNVSVYTVKDDKESVPISDTIIPAVPPPTD-LRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301
Y + + V K S+PI+ ++ PP L+ T + + + W PP N
Sbjct: 18474 YILKLSNVGGTK-SIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHY 18532
Query: 1302 YSPVKNEEDVAELSISPSDNAV--VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1359
+ ++ +S A+ +T LLPG EY+ V +V + PL T +
Sbjct: 18533 IIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACN 18592
Query: 1360 S------PTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHS 1409
P+ + S IT +S V W P I GY + + + ++ +
Sbjct: 18593 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 18652
Query: 1410 RNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTV---SDVPRDLEVVAATPT 1462
+ +T LT G Y + A N G P + + P + +V + +
Sbjct: 18653 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRS 18712
Query: 1463 SLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-----------------TI 1505
S+ ++W P G +PV+ + V ++ A T+
Sbjct: 18713 SVSLAWSKPIYD------------GGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTV 18760
Query: 1506 SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPS 1565
+ LK +Y + A+ G ++ P S+ + I+ P D++ V L +
Sbjct: 18761 TKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLR----KVVVLRA 18816
Query: 1566 SSPVTGYRVTTTPKNGPGPT----KTKTAGPD--QTEMTIEGLQPTVEYVV-------SV 1612
S+ + R+ T K P P K + D Q E+T ++ V ++
Sbjct: 18817 SATL---RLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNL 18873
Query: 1613 YAQNPSGESQPLVQTAVTNI-DRPKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYS 1667
+N SG V V + P L +V DS+ ++WE P +++ Y V
Sbjct: 18874 TLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKR 18933
Query: 1668 SPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT- 1726
+ + + T ++ L+ G Y V+A ++ P T+ + P
Sbjct: 18934 ETTRKAYATI-TNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPL 18992
Query: 1727 ---DLKFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPK--EKTGPMKEINLAPDSSSV 1777
+ VT + + +W P ++TGY V + K EK ++ +
Sbjct: 18993 PPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVK----TLEA 19048
Query: 1778 VVSGLMVATKYEVSVYALKDTLTSRPAQ-GVVTTLENVS-------PPRRARVTDATETT 1829
+SGL +Y V A+ + S P Q GV ++ P V +
Sbjct: 19049 TISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLK 19108
Query: 1830 ITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ----PGTDYKIYLYT 1885
I + ++ + + ++ D GQT + T S T+T L D Y
Sbjct: 19109 IDVPFKGRPQATVNWRKD-----GQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELC 19163
Query: 1886 LNDNARSS--PVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEK 1939
++++A S P+ I P +R + +S+ +SW PP +I+ YI++ ++
Sbjct: 19164 VSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKE 19223
Query: 1940 PGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 1982
S +V + T I L G+EY V A KS
Sbjct: 19224 TTSTTWHIVSQ-AVARTSIKIVRLTTGSEYQFRVCAENRYGKS 19265
Score = 118 bits (295), Expect = 8e-26
Identities = 287/1359 (21%), Positives = 491/1359 (36%), Gaps = 205/1359 (15%)
Query: 780 LLPGRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP 834
++ G +YI VN Y I E E +++ + P P P V ++ S+ V WSRP
Sbjct: 20725 IIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRP 20784
Query: 835 QA----PITGYRIVYSPSVEGSSTEL---NLPETANSVTLSDLQPGVQYNI-TIYAVEEN 886
A I+GY + ++ + +T VT QY + + A +
Sbjct: 20785 IADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQG 20844
Query: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVI 942
S P + D P ++ + T +T+ W+ P SAVTGY V++
Sbjct: 20845 PFSEP---SEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEI- 20900
Query: 943 PVNLPGEHGQRLPIS-----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK- 996
GE + +S R T V+ L PGV YYF+V AV+ + +P+ + +
Sbjct: 20901 ---RQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQA 20957
Query: 997 ---LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--------RQYNVG 1045
L+AP E D V +R T A+ G + V + +G+P + N+G
Sbjct: 20958 KDILEAP-------EIDLDVALR-TSVIAK-AGEDVQVLIPFKGRPPPTVTWRKDEKNLG 21008
Query: 1046 PSVSKYPLRNLQPASEYTVS----------LVAIKGNQESPKATGVFTTL--QPGSSIPP 1093
S ++Y + N +S T+ ++ I+ PK++ V + P +
Sbjct: 21009 -SDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKL 21067
Query: 1094 YNTEVTETTIVITWTP------APRIGFKLGVRPS---QGGEAPREVTSDSGSIV-VSGL 1143
V+ T+ + W P +P I + + R + + +S S ++ +S
Sbjct: 21068 QVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEK 21127
Query: 1144 TPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDI 1203
TP V + G+ + K +P +L ++ + T V+ +SW T PD
Sbjct: 21128 TPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVI-LSW---TKPDF 21183
Query: 1204 TGYRITTTPTNGQQGNSLEEVVHADQS-SCTFD----NLSPGLEYNVSVYTVKDDKESVP 1258
G + T ++G + HA S +C + LE+ V K + V
Sbjct: 21184 DGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVT 21243
Query: 1259 ISDTIIP--AVPPPTDLRFTNIGPDTMRV----------TWAPPPSIDLTNFLVRYSPVK 1306
I + + P DL T+R+ P PSI ++L P+K
Sbjct: 21244 IGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSI---SWLKDGLPLK 21300
Query: 1307 NEEDVAELSISPSDNAVVLT----NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1362
E V S ++N + L+ G +Y V + + + P+ P
Sbjct: 21301 ESEFV---RFSKTENKITLSIKNAKKEHGGKYTVILDNAV-CRIAVPITVITLGPPSKPK 21356
Query: 1363 G-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
G I F +I A+S + W P IT Y I E + +R + + N
Sbjct: 21357 GPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKR-ETSQTNWKMVCSSVARTTFKVPN 21415
Query: 1418 LTPGTEYVVSIVALNGREESPLLIG------QQSTVSDVPRDLEVVAATPTSLLISWDAP 1471
L EY + A N S L+ Q + P + T + ++WDAP
Sbjct: 21416 LVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAP 21475
Query: 1472 AV----TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
V + + E + T P S +GL G+DY VYA G S
Sbjct: 21476 VYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLS 21535
Query: 1528 PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPG 1583
S + +D P DV +I++KW P S + GY + N
Sbjct: 21536 SPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERW 21595
Query: 1584 PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN------PSGESQPLVQTAVTNIDRPKG 1637
+ + + T+ GL P Y + A+N P +S ++ T N+ P
Sbjct: 21596 -VRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENV--PPI 21652
Query: 1638 LAFTDVDVDSI--------------------KIAWESPQGQVSRYRVTYSSPEDGIHELF 1677
+ F D + ++ W ++ + + G LF
Sbjct: 21653 VEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLF 21712
Query: 1678 PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTS 1737
+ T + +G+ YTV +++ + Q T ++FT +T
Sbjct: 21713 V----RDATRDHRGV-----YTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEK 21763
Query: 1738 LSAQWTPP-NVQLTGYRVRVTPKEKTGPM--KEINLAPDSSSVVVSGLMVATKYEVSVYA 1794
++ W P N + K +T + I ++ S L+ +Y+ V A
Sbjct: 21764 MTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSA 21823
Query: 1795 LKDTLTSRP--AQGVVTTLENVSP--PRRARVTDATETTITISWRTKTETITGFQVDA-- 1848
+ RP + VV ++ P P ++ T +IT++W + E+ G ++
Sbjct: 21824 VNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTW-ARPESDGGSEIQQYI 21882
Query: 1849 -----------VPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1897
V + PI T + +TGL G +Y+ ++ + +NA
Sbjct: 21883 LERREKKSTRWVKVISKRPISET------RFKVTGLTEGNEYEFHV--MAENAAGVGPAS 21934
Query: 1898 DASTAIDA---------PSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPP 1944
S I P+ ++ T+ ++ + W P I GYII+ K
Sbjct: 21935 GISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGD 21994
Query: 1945 REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 1983
V T T+T L+ G EY V A+ K +
Sbjct: 21995 WHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGD 22033
Score = 117 bits (293), Expect = 1e-25
Identities = 324/1541 (21%), Positives = 541/1541 (35%), Gaps = 222/1541 (14%)
Query: 612 VEVFITETPSQPNSHPIQ----------WNAPQP---SHISKYILRWRPKNSVGRWKEAT 658
VEV + + P P + I WN P+ S I+ Y++ R +S W + +
Sbjct: 7471 VEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEV-WHKLS 7529
Query: 659 IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
++ L P Y ++ + YG E PV ++ +T +
Sbjct: 7530 STVKDTNFKATKLIPNKEYIFRVAAENMYGVGE-------------PVQASPITAKYQFD 7576
Query: 719 SPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATS 774
P T ++IT + ++W D ++G+ VE + + +P T+
Sbjct: 7577 PPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTT 7636
Query: 775 VNIPDLLPGRKYIVNVY--QISEDGEQSL----ILSTSQTTAPDAPPDPTVDQVDDTSIV 828
+ L +KY V ++ G+ S IL P P PTV V TS+
Sbjct: 7637 YRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVR 7696
Query: 829 VRWSRPQ----APITGY--RIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA 882
+ W++P+ A I Y ++ + + E +P T + L L G +Y+ + A
Sbjct: 7697 LNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH--LLPGLMEGQEYSFRVRA 7754
Query: 883 VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYR 938
V + ES P + PR L+ + +T + WT PE S +T Y
Sbjct: 7755 VNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYI 7814
Query: 939 VDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH-GR------ESKPLTA 991
V+ V G + ++T VT L+ G Y F+V A + G+ E L
Sbjct: 7815 VEKRDVRRKGWQTVDTTV-KDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAK 7873
Query: 992 QQTTKLDAPTNLQFVNETDSTVLVRWTPPR--AQITGYRLTVGLTRRGQPRQYNVGPSVS 1049
T P L V+ T V ++W PP+ R + R R G +
Sbjct: 7874 DTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAG 7933
Query: 1050 KYPLRNLQPASEYTVSLVAIKGNQES-----PKATGVFTTLQPGS-SIPPYNTEVTET-- 1101
+ E T ++ E+ + T + + P S PP + VT+
Sbjct: 7934 PDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGR 7993
Query: 1102 -TIVITWTP------APRIGFKLGVRPSQGGEAPREVTS----DSGSIVVSGLTPGVEYV 1150
I I W P +P IG+ + + P G E V S D V G+ P EYV
Sbjct: 7994 KHIAIAWKPPEKNGGSPIIGYHVEMCP-VGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYV 8052
Query: 1151 YTIQVLRD-GQERDAPIVNKVVT--PLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYR 1207
++ + G + I VV P PT + LE + ++ + E+ + P +R
Sbjct: 8053 LRVRAVNAIGVSEPSEISENVVAKDPDCKPT-IDLETH---DIIVIEGEKLSIP--VPFR 8106
Query: 1208 ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY------NVSVYTV----KDDKESV 1257
PT + +EV +D+ + D++S LE + +YT+ K +
Sbjct: 8107 AVPVPTVSWHKDG-KEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATA 8165
Query: 1258 PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSIS 1317
I+ +I P D++ ++I + ++TW PP T L + + +
Sbjct: 8166 SINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVM 8225
Query: 1318 PSDNAVVLT--NLLPGTEYVVSVSSV-------YEQHESTPLRGRQKTGLDSPTGIDFSD 1368
+N + T +L+P EY V +V Y + ++ + K D P ++ +
Sbjct: 8226 SGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHN 8285
Query: 1369 ITANSFTVHWIAP----RATITGYRIRH--HPEHFSGRPREDRVPHSRNSITLTNLTPGT 1422
TA + T+ W P + I GY I E R E VP + T L G
Sbjct: 8286 PTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPIL--TYTAKGLEEGK 8343
Query: 1423 EYVVSIVALNGREESPLLIGQQSTVSDVPRDL-EVVAATPTSLL----ISWDAPAVTVRY 1477
EY + A N S T + P D +V+ T + I+ DA Y
Sbjct: 8344 EYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPY 8403
Query: 1478 YRITY------------------------GETGGNSP-----VQEFTVPGSKSTATISGL 1508
IT+ GE P Q ++ SK + +
Sbjct: 8404 PTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRV 8463
Query: 1509 KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP---- 1564
+ + +Y + D + P +++ P D++ S+ KW P
Sbjct: 8464 RDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDD 8523
Query: 1565 SSSPVTGYRVTTTPKNGP-GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
S + Y + K P T+ + ++ L EY+ V A+N G P
Sbjct: 8524 GGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPP 8583
Query: 1624 LVQTAVT------NIDRPKGLAFTDVDVDSIKIAWESPQ-------GQVSRYRVTYSSPE 1670
V + D P DV +S+ + W P+ G R S+
Sbjct: 8584 CVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHW 8643
Query: 1671 DGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD------DMESQPLIGTQSTAIPA 1724
+++ A + GL G Y V A + S P + P
Sbjct: 8644 SRVNKSLL----NALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPG 8699
Query: 1725 PTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV--- 1777
P + T + T++ +W PP ++ GY V K+ G + V
Sbjct: 8700 PPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFV---DKQLVGTNEWSRCTEKMIKVRQY 8756
Query: 1778 VVSGLMVATKYEVSVYALKDTLTSRPAQ-GVVTTLENVSPPRRARVTDATETTITISWRT 1836
V + Y++ V A+ P + VT E PP A E +++
Sbjct: 8757 TVKEIREGADYKLRVSAVNAAGEGPPGETQPVTVAEPQEPP-------AVELDVSVKGGI 8809
Query: 1837 KTETITGFQVDAVPANGQTPIQRTIKPD--------------VRSYTITGLQPGTDYKIY 1882
+ ++ AV P + K + +S I D+ Y
Sbjct: 8810 QIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRY 8869
Query: 1883 LYTLNDNARSSPVVIDASTAIDAPS---NLRFLATTPNSLLVSWQPPR----ARITGYII 1935
+ T N+ S D P +L+ + T L++W P + ITG+II
Sbjct: 8870 VITAT-NSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFII 8928
Query: 1936 KYEKPGSPP-REVVPRPRPGVTEATITGLEPGTEYTIYVIA 1975
+ + R+ + R ++ ITGL G EY VIA
Sbjct: 8929 ERKDAKMHTWRQPIETER---SKCDITGLLEGQEYKFRVIA 8966
Score = 117 bits (293), Expect = 1e-25
Identities = 292/1326 (22%), Positives = 488/1326 (36%), Gaps = 202/1326 (15%)
Query: 811 PDAPPDPT-VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSV 865
P P P + V + + W P+ + IT Y I + + ++ +
Sbjct: 9912 PGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTY 9971
Query: 866 TLSDLQPGVQYNITIYAVEENQESTPVVIQQETT-------GTPRSDTVPSPRDLQFVEV 918
T+ L G +Y I A + P+ + ET G P TV S V
Sbjct: 9972 TIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSS--------V 10023
Query: 919 TDVKVTIMWTPPE----SAVTGYRVDVIPVNLPG-EHGQRLPISRNTFA---EVTGLSPG 970
T +T+ W PE S VTGY +++ + R PI T +VTGL G
Sbjct: 10024 TRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEG 10083
Query: 971 VTYYFKVFAVSHGR------ESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR--- 1021
Y F+V+A++ S P TA+ P + + T S+ + W+PP
Sbjct: 10084 SDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDG 10143
Query: 1022 -AQITGYRLTVGLTRRGQPRQYNVGPSV----SKYPLRNLQPASEYT--VSLVAIKGNQE 1074
+++TGY V G+ ++ G +K + L+ + Y V V I G E
Sbjct: 10144 GSKVTGY--IVEYKEEGK-EEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGE 10200
Query: 1075 SPKATGVFTT--------LQPGSSIPP----YNTEVTETTIVITWTPAPRIGFKLGVRPS 1122
+ T V LQ +S+ + V ++ P P + + + R +
Sbjct: 10201 PGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNER-T 10259
Query: 1123 QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT---PLSPPTN 1179
EA E T+ S S+V+ + VY++ + ER I+ V+ P+ P
Sbjct: 10260 LPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFL 10319
Query: 1180 LHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239
H N + S E IT Y I ++ + + V + + T L
Sbjct: 10320 AHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTV--TRQNATVQGLIQ 10377
Query: 1240 GLEY--------NVSVYTVKDDKESVPISDTIIPAVPP-PTDLRFTNIGPDTMRVTWAPP 1290
G Y ++ + + E++ I + I VP P DL + +T+ +TW PP
Sbjct: 10378 GKAYFFRIAAENSIGMGPFVETSEALVIREPI--TVPERPEDLEVKEVTKNTVTLTWNPP 10435
Query: 1291 P---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHES 1347
++ N+++ + E+ + + + L G Y VS+V +
Sbjct: 10436 KYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQG 10495
Query: 1348 TPLRGRQ----KTGLDSPT-GIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPR 1402
P + K L PT +DF D T+ + +TG +SG+P+
Sbjct: 10496 KPSFCTKPITCKDELAPPTLHLDFRD----KLTIR-VGEAFALTG--------RYSGKPK 10542
Query: 1403 ------EDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQST--------VS 1448
+D + T TP T + I A ++ + ST V+
Sbjct: 10543 PKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVN 10602
Query: 1449 DVPRDLEVVA------ATPTSLLISWDAP----AVTVRYYRITYGETGGN--SPVQEFTV 1496
V R V T ++ISW P + Y I E G + PV T
Sbjct: 10603 VVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPV---TS 10659
Query: 1497 PGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEI-DKPSQMQVTDVQ 1554
+K+T +S L G DY ++A G S P S + R + D P Q VT+V
Sbjct: 10660 ASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVT 10719
Query: 1555 DNSISVKWLP---SSSPVTGY---RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEY 1608
+S V W P+T Y + T K TK T+ + L +Y
Sbjct: 10720 KDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIH--PYTKFRVPDLLEGCQY 10777
Query: 1609 VVSVYAQN------PSGESQPL-VQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQ----G 1657
V A+N PS S+P+ + + P D +S+ + W+ P+
Sbjct: 10778 EFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGS 10837
Query: 1658 QVSRYRVTYSSPEDGI-HELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLI 1715
++ Y V Y D P+ +T ++ GLR G Y V+A++ ES P
Sbjct: 10838 KILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDP-- 10895
Query: 1716 GTQSTAIPAPTDLKFTQVTP-TSLSAQWTPPNVQLTGYRVRVT------PKEKTGPMKEI 1768
+P P +K P L A G +R++ P K KE
Sbjct: 10896 ----AHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKED 10951
Query: 1769 NLAPDSSSVVVSGLMVATKYEV--------SVYAL--KDTLTSRPAQGVVTTLENVSPPR 1818
AP + + V+ V +K E+ +Y+L ++ S+ V L+ PPR
Sbjct: 10952 RDAPTKARIDVT--PVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPR 11009
Query: 1819 RARVTDATETTITISWRTKTE----TITGFQVDA--VPANGQTPIQRTIKPDVRSYTITG 1872
V++ + + ++W+ + IT + V+ V + +P+ T K +S+
Sbjct: 11010 DLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKK--KSHFAKH 11067
Query: 1873 LQPGTDYKIYLYTLNDNARSSPV-------VIDASTAIDAPSNLRFLATTPNSLLVSWQP 1925
L G Y + N R V +D P +L + + + W
Sbjct: 11068 LNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNK 11127
Query: 1926 P----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 1981
P + ITGY+++Y++ G+ ++ + E +TGL+ G Y V K
Sbjct: 11128 PDRDGGSPITGYLVEYQEEGT--QDWIKFKTVTNLECVVTGLQQGKTYRFRV-------K 11178
Query: 1982 SEPLIG 1987
+E ++G
Sbjct: 11179 AENIVG 11184
Score = 112 bits (281), Expect = 3e-24
Identities = 265/1361 (19%), Positives = 500/1361 (36%), Gaps = 176/1361 (12%)
Query: 766 LDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT 825
+D + TS I + G K + ++ G+ ++ P + V + D
Sbjct: 6740 IDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDG 6799
Query: 826 SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPG-VQYNIT 879
+ + W P + I GY +V ++ + L + T++ LQ G V+Y
Sbjct: 6800 EVSLAWEEPLTDGGSKIIGY-VVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFR 6858
Query: 880 IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVT 935
+ A PV + D P ++ +V V++ W PPE + +T
Sbjct: 6859 VSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEIT 6918
Query: 936 GYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT 995
Y +++ + + A VT + G Y F+V A + KP A
Sbjct: 6919 NYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFV 6978
Query: 996 KL-------DAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR---- 1040
K+ P NL ++T S+V ++W PP + I GY + G+
Sbjct: 6979 KVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGY--IIERCEEGKDNWIRC 7036
Query: 1041 QYNVGPSVSKYPLRNLQPASE--YTVSLVAIKGNQESPKATGVFTT----LQPGSSIPPY 1094
+ P ++ Y + L+ ++ Y VS G + + G T ++P + +
Sbjct: 7037 NMKLVPELT-YKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAF 7095
Query: 1095 NTEV-----TETTIVI--TWTPAPRIGFKLGVRPSQGGEAPREVT-SDSGSIVVSGLTPG 1146
+ TI++ T P P + G + + G+ + T S +V+S
Sbjct: 7096 KDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERS 7155
Query: 1147 VEYVYTIQVLRDGQERDAPI-VNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD--- 1202
+ +YT+++ + I VN + P +P + D+ LT WE PD
Sbjct: 7156 DKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLT--WE---PPDDDG 7210
Query: 1203 ---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY--NVSVYTVKDDKESV 1257
+TGY + + + + + V T +L G EY V E
Sbjct: 7211 GSPLTGYVVEKREVSRKTWTKVMDFV--TDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7268
Query: 1258 PISDTIIPAVP-----PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEE 1309
+ + + + P PP ++++ + +++ +TW PP + + ++V P +++
Sbjct: 7269 YVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDK 7328
Query: 1310 DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDI 1369
VA ++ + +T L G Y V ++ Q S P R ++ +D +
Sbjct: 7329 WVA-CGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEI-----QAVDTQEA 7382
Query: 1370 TANSFTVHWIAPRATITGYRIRHHPEHFSGRP-------REDRVPHSRNSITLTNLTPGT 1422
V +A G +I P +G+P + D + IT+ N+
Sbjct: 7383 PEIFLDVKLLAGLTVKAGTKI-ELPATVTGKPEPKITWTKADMILKQDKRITIENVP--K 7439
Query: 1423 EYVVSIVALNGREESPLLI------GQQSTVSDV--------PRDLEVVAATPTSLLISW 1468
+ V+IV + +I G+ + V +V P ++ T S L++W
Sbjct: 7440 KSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTW 7499
Query: 1469 DAP----AVTVRYYRITYGETGG------NSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
+ P + Y + T +S V++ +K L P +Y V
Sbjct: 7500 NPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATK-------LIPNKEYIFRV 7552
Query: 1519 YAVTGRG-DSPASSKPISINYRTE-IDKPSQMQVTDVQDNSISVKWL----PSSSPVTGY 1572
A G P + PI+ Y+ + P++++ +D+ +++++ W SP+TGY
Sbjct: 7553 AAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGY 7612
Query: 1573 RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LV 1625
V + + T ++GL +Y V A+N +G +P L+
Sbjct: 7613 WVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILI 7672
Query: 1626 QTAVTNIDRPKGLAFTDVDVDSIKIAWESPQ--GQVSRYRVTYSSPEDGIHELFPAPDGE 1683
+ + P DV S+++ W P+ G + G E +G
Sbjct: 7673 KDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGV 7732
Query: 1684 EDTAE-LQGLRPGSEYTVSVVALHDDMESQ------PLIGTQSTAIPAPTD-LKFTQVTP 1735
T L GL G EY+ V A++ ES+ P++ + P+P L+ +T
Sbjct: 7733 PTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITK 7792
Query: 1736 TSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS 1791
+ +WT P +T Y V + G + ++ + V+ L E S
Sbjct: 7793 NTADLKWTVPEKDGGSPITNYIVEKRDVRRKG-WQTVDTTVKDTKCTVTPLT-----EGS 7846
Query: 1792 VYALKDTLTSRPAQGVVTTLEN----------VSPPRRARVTDATETTITISWRTKT--- 1838
+Y + + Q T +E+ PP V D T+ + + W
Sbjct: 7847 LYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDG 7906
Query: 1839 -ETITGFQVDAVPANGQTPIQ--RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP- 1894
I + ++ G ++ +T PD ++ +T + GT+ + + N+ P
Sbjct: 7907 GRPIQRYVIEKKERLGTRWVKAGKTAGPDC-NFRVTDVIEGTEVQFQVRAENEAGVGHPS 7965
Query: 1895 ------VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPP 1944
+ D ++ P +L + ++W+PP + I GY ++ G+
Sbjct: 7966 EPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEK 8025
Query: 1945 -REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
V RP + G+ P EY + V A+ SEP
Sbjct: 8026 WMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEP 8066
Score = 107 bits (266), Expect = 2e-22
Identities = 292/1356 (21%), Positives = 513/1356 (37%), Gaps = 189/1356 (13%)
Query: 727 SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQ--YLDLPSTA--TSVNIPDLLP 782
+VTE+T+ V+SW D G ++++ + ++ + + + ++ S T + + LL
Sbjct: 15258 AVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 15316
Query: 783 GRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAP 837
G +YI VN Y + E E +L+ + PD P +P V + S+VV W P +
Sbjct: 15317 GNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDS- 15375
Query: 838 ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ-------PGVQYNITIYAVEENQEST 890
G + + VE N TL+DL+ G +Y I A S
Sbjct: 15376 -DGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISA 15434
Query: 891 PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNL 946
P P + + ++ + ++I W P S +TGY V++ L
Sbjct: 15435 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIA---L 15491
Query: 947 PGEHGQRLPIS----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD---A 999
P E ++ + T +TGL+ Y +++A++ +P T K +
Sbjct: 15492 PEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRML 15551
Query: 1000 PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR---QYNVGPSVSKYPLRNL 1056
P ++ + V +R RL V + R P + G S+ K ++
Sbjct: 15552 PPEIELDADLRKVVTIR------ACCTLRLFVPIKGRPAPEVKWARDHGESLDK---ASI 15602
Query: 1057 QPASEYTVSLVAIKGNQESPK----------ATGVFTTLQ----PGSSIPPYNTEVTETT 1102
+ S YT+ +V +S K + F ++ PG EVT+T+
Sbjct: 15603 ESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTS 15662
Query: 1103 IVITWTPAPRI--GFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQ 1154
+ +TW P P + G K+ + E+ R+ S S V L G Y + +
Sbjct: 15663 VTLTWDP-PLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYF--R 15719
Query: 1155 VLRDGQ------ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITG 1205
VL + + A V PL P ++ ++ +++SWE+ I G
Sbjct: 15720 VLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNS--VSLSWEKPEHDGGSRILG 15777
Query: 1206 YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKE-SVPI 1259
Y I T G + V +++ T L G EY+ V + D ++ SVP+
Sbjct: 15778 Y-IVEMQTKGSDKWATCATVKVTEATIT--GLIQGEEYSFRVSAQNEKGISDPRQLSVPV 15834
Query: 1260 --SDTIIPAVPPPTDLRFTNIGPDTMRV----TWAPPPSIDLTNFLVRYSPVKNEEDVAE 1313
D +IP FT + + ++V P P++ V P+K
Sbjct: 15835 IAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNV---PLK---QTTR 15888
Query: 1314 LSISPSDNAVVLTNLLPGTE----YVVSV-SSVYEQHESTPLRGRQKTGLDSPTG-IDFS 1367
++ ++N +LT E YVV + +S E E+ + K G PTG +
Sbjct: 15889 VNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG--PPTGPVKMD 15946
Query: 1368 DITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423
++TA+S T+ W P+ ++I Y + + + + +R +I L G E
Sbjct: 15947 EVTADSITLSWGPPKYDGGSSINNYIVEKR-DTSTTTWQIVSATVARTTIKACRLKTGCE 16005
Query: 1424 YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPT-------SLLISWDAP----A 1472
Y I A N +S L + TV+ P + TP S+ + W+ P
Sbjct: 16006 YQFRIAAENRYGKSTYL-NSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGG 16064
Query: 1473 VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSK 1532
V Y + E V+ P ++ +GL+ GV+Y V A G S
Sbjct: 16065 SRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKV 16124
Query: 1533 PISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTK 1588
R D P + + V NS++++W S +TGY V K
Sbjct: 16125 SECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKAS 16184
Query: 1589 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-SQPLVQT-AVTNIDR--PKGLAFTDVD 1644
T + GL Y V A+N +G S+P T A+T D P ++
Sbjct: 16185 FTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKY 16244
Query: 1645 VDSIKI-AWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVV 1703
D+I + A ES + Y P I + G+++ + L S + +
Sbjct: 16245 KDTIVVHAGESFKVDAD----IYGKPIPTIQWI----KGDQELSNTARLEIKSTDFATSL 16296
Query: 1704 ALHDD---------MESQPLIGTQSTAI-------PAPTD--LKFTQVTPTSLSAQWTPP 1745
++ D ++++ + G +S + P P + + + VT + W PP
Sbjct: 16297 SVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPP 16356
Query: 1746 NVQLTGYRV--RVTPKEKTGPM--KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1801
+Q G + + + +T + ++ + S V+ L+ +Y + A+
Sbjct: 16357 -LQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVG 16415
Query: 1802 RPAQGVVTTLEN--VSP--PRRARVTDATETTITISWRTKT----ETITGFQVDAVPANG 1853
P + +N V P P+ VT T+ ++ + W I G+ ++ G
Sbjct: 16416 EPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEG 16475
Query: 1854 --QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDA-STAID------ 1904
T + + ++R +TGL DY+ + N S P A A D
Sbjct: 16476 IRWTRCHKRLIGELR-LRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPG 16534
Query: 1905 APSNLRFLATTPNSLLVSWQPP----RARITGYIIK 1936
P+N + + T +S+ +SW P I GYI++
Sbjct: 16535 PPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVE 16570
Score = 106 bits (265), Expect = 2e-22
Identities = 338/1705 (19%), Positives = 582/1705 (34%), Gaps = 213/1705 (12%)
Query: 606 PSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGH 662
P GPVE+ + + W P S I YIL R + + W +
Sbjct: 14168 PGPPGPVEI----SNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRL-LWTVVSEDIQ 14222
Query: 663 LNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLV 722
+ L G Y ++ ++ YG E PV S V P
Sbjct: 14223 SCRHVATKLIQGNEYIFRVSAVNHYGKGE-------------PVQSEPVKMVDRFGPPGP 14269
Query: 723 ATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778
V+ +T ++ VSW D ++G+ VE + + + P + +
Sbjct: 14270 PEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVT 14329
Query: 779 DLLPGRKYIVNVYQISEDG------EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS 832
L G Y V + G +L P P +P V S + W
Sbjct: 14330 GLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWG 14389
Query: 833 RPQ----APITGYRIVYSPSVEGSSTELNLPETANSVT---LSDLQPGVQYNITIYAVEE 885
+P ITGY +V V + + TA +T + DLQ +YN I A+ +
Sbjct: 14390 KPHYDGGLEITGY-VVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAIND 14448
Query: 886 NQESTPVVIQQ-ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPV 944
P VI E + +L+ V ++I P V
Sbjct: 14449 AGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKD 14508
Query: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYF--KVFAVSHGRESKPLTAQQTTKLDAP-- 1000
N+ ++ + NT + + P Y K K LD P
Sbjct: 14509 NINLKNRANI---ENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGP 14565
Query: 1001 -TNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSK-----YPLR 1054
NL+ + T +V + W P G R+T + + + + + + +K Y +
Sbjct: 14566 VLNLRPTDITKDSVTLHWDLPLID-GGSRITNYIVEKREATRKSYSTATTKCHKCTYKVT 14624
Query: 1055 NLQPASEYTVSLVAIK--GNQESPKATGVFTTLQPGSSIPPYNT-EVTETTIVITWTPAP 1111
L EY ++A G E + T + S N ++T++T+ + W P P
Sbjct: 14625 GLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAW-PKP 14683
Query: 1112 R-------IGFKLGVRPSQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVL----RDG 1159
+ G+ + + +G + +T+ G VV LT G EY + + + R
Sbjct: 14684 KHDGGSKITGYVIEAQ-RKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSA 14742
Query: 1160 QERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE--RSTTPDITGYRITTTPTNGQQ 1217
P++ K T L L L V+ + + + P + + T T G Q
Sbjct: 14743 PRESRPVIVKEQTMLP---ELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQ 14799
Query: 1218 G-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAV-----PPPT 1271
+ V ++ T N++ + + Y + + D I V PP
Sbjct: 14800 ILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTG 14859
Query: 1272 DLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNL 1328
++F + D + +W PP + + ++N++V + V EL+ + T L
Sbjct: 14860 PIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWV-ELATTVIRTTYKATRL 14918
Query: 1329 LPGTEYVVSVSS-----VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAP- 1381
G EY V + V S + + P G + +T +S T+ W P
Sbjct: 14919 TTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPL 14978
Query: 1382 ---RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------ 1432
+ I GY + + + N + LT G Y ++A N
Sbjct: 14979 SDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSK 15038
Query: 1433 -GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1491
+ P+L P L + T T + W P T + +Y + P
Sbjct: 15039 PSKPSEPMLALDPIDPPGKPVPLNITRHTVT---LKWAKPEYTGGFKITSYIVEKRDLPN 15095
Query: 1492 QEFTVPG----SKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPS 1546
+ ++ T+SGL Y V A G SP S +I R +++ P
Sbjct: 15096 GRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPK 15155
Query: 1547 QMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTK------TKTAGPDQTEMTIE 1600
+D I +R+ P PT + G + E+ I
Sbjct: 15156 IKVDVKFKDTVI-------LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIA 15208
Query: 1601 GLQPTV---------EYVVSVYAQNPSGESQPLVQTAVTNIDRP----KGLAFTDVDVDS 1647
+ ++ A NP G ++ + V +DRP LA T+V +
Sbjct: 15209 DFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKV--LDRPGPPEGPLAVTEVTSEK 15266
Query: 1648 IKIAWESP---QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVA 1704
++W P G + + + A + + ++ L G+EY V+A
Sbjct: 15267 CVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMA 15326
Query: 1705 LH-----DDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPPN----VQLTGYRV 1754
++ + +ES+P++ P P + + T +T S+ W P+ ++ Y V
Sbjct: 15327 VNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIV 15386
Query: 1755 RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYA-----LKDTLTSRPAQGVVT 1809
K +K VSGL +YE + A + + P
Sbjct: 15387 ERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACD 15446
Query: 1810 TLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVD-AVPANGQTPIQRTIKP- 1863
T+ PP RV D + ++I+I+W ITG+ V+ A+P + I + P
Sbjct: 15447 TVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQI---VTPP 15503
Query: 1864 ---DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAS---------TAIDAPSNLRF 1911
SYTITGL +YKI +Y +N P ++ + I+ ++LR
Sbjct: 15504 AGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRK 15563
Query: 1912 LATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTI 1971
+ T + P +K+ + + I G +
Sbjct: 15564 VVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLIVGNVNRFDSGK 15623
Query: 1972 YVIALKNNQKSEPLIGRKKTDELP--------QLVTLPHPNL-HGPEILDVPSTVQKTPF 2022
Y++ ++N+ S+ + + P + VT L P +LD S ++ +
Sbjct: 15624 YILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKN--Y 15681
Query: 2023 VTHPGYDTGNGIQLPGTSGQQPS--VGQQM--------IFEEHGFRRTTPPTTATPIRHR 2072
+ T T+ + S V Q + E+ + P TA ++
Sbjct: 15682 IVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKAS 15741
Query: 2073 PRPYPPNVGQEALSQTT-----ISW-APFQDTSE----YIISCHPVGTDEEPLQFRVPGT 2122
RP PP G+ L T +SW P D YI+ G+D+ V
Sbjct: 15742 ERPLPP--GKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATV--K 15797
Query: 2123 STSATLTGLTRGATYNIIVEALKDQ 2147
T AT+TGL +G Y+ V A ++
Sbjct: 15798 VTEATITGLIQGEEYSFRVSAQNEK 15822
Score = 106 bits (264), Expect = 3e-22
Identities = 321/1571 (20%), Positives = 563/1571 (35%), Gaps = 259/1571 (16%)
Query: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWR 646
YG G+ +P++ P V + + N+ I+W P+ S I+ Y++ +
Sbjct: 18973 YGIGLPAETTEPVKVSEPPLPPGRVTLVDVTR--NTATIKWEKPESDGGSKITGYVVEMQ 19030
Query: 647 PKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPV 706
K S +W T L + TI GL G Y ++ ++ + G + + PV
Sbjct: 19031 TKGSE-KWSTCTQVKTLEA-TISGLTAGEEYVFRVAAVNEKGRSDPRQL-------GVPV 19081
Query: 707 TSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL 766
+ + E P L + +V V + +R + + +E +
Sbjct: 19082 IARDI--EIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVN-V 19138
Query: 767 DLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDP---TVDQVD 823
T TS++I + K V Y++ I D P P +D+V
Sbjct: 19139 SSSKTVTSLSIKE---ASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVS 19195
Query: 824 DTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNIT 879
SI + W+ P+ I+ Y + + + ++ S+ + L G +Y
Sbjct: 19196 CDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFR 19255
Query: 880 I-----YAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE--- 931
+ Y ES+ VV + P S P P + V T + + W P
Sbjct: 19256 VCAENRYGKSSYSESSAVVAEY-----PFSPPGP-PGTPKVVHATKSTMLVTWQVPVNDG 19309
Query: 932 -SAVTGYRVDVIP-VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA---VSHGRES 986
S V GY ++ ++ ++ I+ +T +V+GL G+ Y ++V+A G+ S
Sbjct: 19310 GSRVIGYHLEYKERSSILWSKANKILIA-DTQMKVSGLDEGLMYEYRVYAENIAGIGKCS 19368
Query: 987 K---PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR----AQITGY-----RLTVG-- 1032
K P+ A+ D P + N T +V ++W+ P A+ITGY L G
Sbjct: 19369 KSCEPVPARDPC--DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRW 19426
Query: 1033 --------------LTRRGQPRQY-------NVGPSVSKYPLRNLQPASEYTVSLVAIKG 1071
+T + ++Y N SVS+ SE T ++ +K
Sbjct: 19427 LKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSE--------PSESTGPII-VKD 19477
Query: 1072 NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGF-KLGVRPSQGGEAPRE 1130
+ E P+ V ++ I EV + I P P I + K G+ +
Sbjct: 19478 DVEPPR---VMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEII 19534
Query: 1131 VTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGV 1190
T + + V Y + + R + KV+ PP LE N T
Sbjct: 19535 STDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAG-PLEINGLTAE 19593
Query: 1191 -LTVSWERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY--- 1243
++SW R DI Y + T+ E + +SC L G EY
Sbjct: 19594 KCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQ--MTSCKVTKLLKGNEYIFR 19651
Query: 1244 --NVSVYTVKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTN 1297
V+ Y V + ESV I VP PPT L T++ ++M + W+ P S +++
Sbjct: 19652 VTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISG 19711
Query: 1298 FLVRYSPVKNEEDVAELSISP-SDNAVVLTNLLPGTEYVVSV-----SSVYEQHESTPL- 1350
+++ KN ++ P D V T L G EY V + + E++PL
Sbjct: 19712 YIIERRE-KNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLI 19770
Query: 1351 RGRQKTGLDS-PTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDR 1405
R L S P+ D + T+ W+ P A ITGY + + + +
Sbjct: 19771 RAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEY--KKSDDTDWKTS 19828
Query: 1406 VPHSRNS-ITLTNLTPGTEYVVSIVALN-----------------GREESPLLIGQQSTV 1447
+ R + T++ LT G EYV + ++N REE PL
Sbjct: 19829 IQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLF----DID 19884
Query: 1448 SDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT-VPGSKSTATI- 1505
S++ + L V A ++ + + V + + + + + + S+++ TI
Sbjct: 19885 SEMRKTLIVKAGASFTMTVPFRGRPVP----NVLWSKPDTDLRTRAYVDTTDSRTSLTIE 19940
Query: 1506 -SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW-L 1563
+ YT+T+ V A+S + + P+ + V DV S + W +
Sbjct: 19941 NANRNDSGKYTLTIQNVLS-----AASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDV 19995
Query: 1564 PSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
P + +PV Y + + T ++ + LQ Y V +N G
Sbjct: 19996 PENDGGAPVKNYHIEKREASKKAWVSV-TNNCNRLSYKVTNLQEGAIYYFRVSGENEFGV 20054
Query: 1621 SQPLVQTAVTNIDR----PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTY--SSPEDGIH 1674
P I P+ L T + DS+ + W P+ V Y + E G
Sbjct: 20055 GIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQK 20114
Query: 1675 ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVT 1734
+ + GLR SEY V A E+Q + P +L +
Sbjct: 20115 NWVKCAVAKSTHHVVSGLRENSEYFFRVFA-----ENQ-------AGLSDPREL----LL 20158
Query: 1735 PTSLSAQWTPPNVQL-----------TGYRVRVTPKEKTGPMKEINLAPD---------- 1773
P + Q PP + + G ++V P+ ++ L+ D
Sbjct: 20159 PVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRF 20218
Query: 1774 SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV------VTTLENVSPPR-RARVTDAT 1826
++ + L + K V+ A + +T+ + G + L+ PP ++D T
Sbjct: 20219 NTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDIT 20278
Query: 1827 ETTITISWR---------------TKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTIT 1871
E ++T+ W K ET T AV + RT+ +
Sbjct: 20279 EESVTLKWEPPKYDGGSQVTNYILLKRETST-----AVWTEVSATVARTM------MKVM 20327
Query: 1872 GLQPGTDYKIYL-----YTLNDNARSSPVVIDASTAIDAPSNLRFLA-TTPNSLLVSWQP 1925
L G +Y+ + + ++D+ S+ V + P + ++ T S+ V W
Sbjct: 20328 KLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHE 20387
Query: 1926 P----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL----- 1976
P + + GY ++ + S + + T +T + G Y V A
Sbjct: 20388 PVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGV 20447
Query: 1977 -KNNQKSEPLI 1986
K + SEP++
Sbjct: 20448 GKPSHPSEPVL 20458
Score = 106 bits (264), Expect = 3e-22
Identities = 279/1348 (20%), Positives = 495/1348 (36%), Gaps = 168/1348 (12%)
Query: 773 TSVNIPDLLPGRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSI 827
TS + LL G +YI VN Y + E E I + T P P + V S+
Sbjct: 19635 TSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESM 19694
Query: 828 VVRWSRPQAP----ITGYRIVYSPSVEGSSTELNL-PETANSVTLSDLQPGVQYNITIYA 882
+ WSRP++ I+GY I +N P V + L+ G +Y +YA
Sbjct: 19695 TLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYA 19754
Query: 883 VEENQESTPVVIQQETTGTPRSDT---VPSPRDL-QFVEVTDVKVTIMWTPP----ESAV 934
+ + + + ET+ R++ +PSP + V+ +TI W P + +
Sbjct: 19755 ----ENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPI 19810
Query: 935 TGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA--- 991
TGY V+ + + + R T ++GL+ G Y F+V +V+ S P +
Sbjct: 19811 TGYTVEYKKSD-DTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDP 19869
Query: 992 QQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP------------ 1039
Q + + +E T++V+ G T+ + RG+P
Sbjct: 19870 QIAKEREEEPLFDIDSEMRKTLIVK--------AGASFTMTVPFRGRPVPNVLWSKPDTD 19921
Query: 1040 ---RQYNVGPSVSKYPLR----NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIP 1092
R Y V + S+ L N + +YT+++ + V T P ++I
Sbjct: 19922 LRTRAY-VDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNIT 19980
Query: 1093 PYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDSG--SIVVSGLT 1144
+VT+ + V++W AP + + R + +A VT++ S V+ L
Sbjct: 19981 VQ--DVTKESAVLSWDVPENDGGAPVKNYHIEKREASK-KAWVSVTNNCNRLSYKVTNLQ 20037
Query: 1145 PGVEYVYTIQVLRD---GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW---ERS 1198
G Y + + + G + K+ SPP L + + V +++W E
Sbjct: 20038 EGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSV-SLTWLKPEHD 20096
Query: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
I Y + Q N ++ V A + L EY V+ S P
Sbjct: 20097 GGSRIVHYVVEALEKG--QKNWVKCAV-AKSTHHVVSGLRENSEYFFRVFAENQAGLSDP 20153
Query: 1259 ISDTIIPAV------PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVA 1312
+ ++P + PP D++ N T+ V +D+ V D
Sbjct: 20154 -RELLLPVLIKEQLEPPEIDMK--NFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGV 20210
Query: 1313 ELSISPSDNA-VVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD--------SPTG 1363
L + N + NL + V+ + + + G K ++ PTG
Sbjct: 20211 PLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTG 20270
Query: 1364 -IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNL 1418
+ SDIT S T+ W P+ + +T Y + E + E +R + + L
Sbjct: 20271 PVVISDITEESVTLKWEPPKYDGGSQVTNYILLKR-ETSTAVWTEVSATVARTMMKVMKL 20329
Query: 1419 TPGTEYVVSIVALNGR------EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA 1472
T G EY I A N + + + + T P V T S+ + W P
Sbjct: 20330 TTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPV 20389
Query: 1473 VT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSP 1528
V Y + + + + + ++ + G+ Y VYA G
Sbjct: 20390 SNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGK 20449
Query: 1529 ASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGP 1584
S + + P +++TD+ NS+S+ W S +TGY V
Sbjct: 20450 PSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRW 20509
Query: 1585 TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-SQPL-VQTAVTNIDRPKGLAFTD 1642
TK +T+ I GL +Y V+A+N G S P V +T ID G D
Sbjct: 20510 TKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVI-D 20568
Query: 1643 VDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSV 1702
+ ++ ++ + G + R S E + D E T L + ++ +
Sbjct: 20569 LPLEYTEVV-KYRAGTSVKLRAGISGKPAPTIEWYK-DDKELQTNALVCVENTTDLASIL 20626
Query: 1703 VALHDDMES-------QPLIGTQSTAI---------PAPTDLKFTQVTPTSLSAQWTPP- 1745
+ D + S + +G+ S I P ++F VT ++ W PP
Sbjct: 20627 IKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPA 20686
Query: 1746 ---NVQLTGYRVRVTPKEKTGPM--KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT 1800
++T Y + K +T + ++ + + + ++ +Y V A+
Sbjct: 20687 DDGGAKITHY---IVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGI 20743
Query: 1801 SRPAQGVVTTLENV----SPPRRARVTDATETTITISWRTKT----ETITGFQV---DAV 1849
P + +N PP VT T+ ++T+ W I+G+ + D
Sbjct: 20744 GEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKK 20803
Query: 1850 PANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNAR---SSPVVI-DASTAIDA 1905
++ TI+ D R +TGL +DY+ + +N + S P A+ ID
Sbjct: 20804 SLGWFKVLKETIR-DTRQ-KVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDP 20861
Query: 1906 P---SNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVP-RPRPGVTE 1957
P + +R +T +S+ + W P + +TGY+++ + V + TE
Sbjct: 20862 PGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTE 20921
Query: 1958 ATITGLEPGTEYTIYVIALKNNQKSEPL 1985
++ L+PG Y V A+ + EP+
Sbjct: 20922 YVVSNLKPGVNYYFRVSAVNCAGQGEPI 20949
Score = 103 bits (256), Expect = 3e-21
Identities = 283/1422 (19%), Positives = 486/1422 (34%), Gaps = 190/1422 (13%)
Query: 730 EITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRK 785
+IT S ++W D ++G+ VE + +D T +PDL+ G++
Sbjct: 7193 DITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFV-TDLEFTVPDLVQGKE 7251
Query: 786 YIVNVYQISE--DGEQSLILSTSQTTAPDAPPDP--TVDQVDDT--SIVVRWSRPQ---- 835
Y+ V ++ GE + + + P PDP V D T SI + W P+
Sbjct: 7252 YLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGG 7311
Query: 836 APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ 895
+ I GY + P P + ++ L+ G Y + A+ S P
Sbjct: 7312 SRIKGYIVERCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPT 7371
Query: 896 QETTGTPRSDTVPSPRDLQFVEVTDVKV-------TIMWTPPESAVTGYRVDVIPVNLPG 948
+E + D++ + VK + PE +T + D+I
Sbjct: 7372 EEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKR 7431
Query: 949 EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE 1008
+ +P + S TY + V GR + + K P +
Sbjct: 7432 ITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVC-GRATAVVEVNVLDKPGPPAAFDITDV 7490
Query: 1009 TDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTV 1064
T+ + L+ W PPR ++IT Y + T + + + + L P EY
Sbjct: 7491 TNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIF 7550
Query: 1065 SLVA--IKGNQESPKATGVFTTLQPGSSIPPYNTE---VTETTIVITWTP------APRI 1113
+ A + G E +A+ + Q PP E +T+ + +TW +P
Sbjct: 7551 RVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPIT 7610
Query: 1114 GF---KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTI---QVLRDGQERDAPIV 1167
G+ +L + + D+ + V GLT +Y + + + G+ +
Sbjct: 7611 GYWVERLDPDTDKWVRCNKMPVKDT-TYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEP 7669
Query: 1168 NKVVTPLSPPTNLHLEANPDTGVLTV--SWERSTTPDITGYRITTTPTNGQQGNSLEEVV 1225
+ P+ PP D G +V +W T P+ G + +E V
Sbjct: 7670 ILIKDPIDPPWPPGKPTVKDVGKTSVRLNW---TKPEHDGGAKIESYVIEMLKTGTDEWV 7726
Query: 1226 HADQSSCTFDNLSPGL----EYNVSVYTVKDDKESVPI--SDTIIPAVP-----PPTDLR 1274
+ T +L PGL EY+ V V ES P SD ++ PP L
Sbjct: 7727 RVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLE 7786
Query: 1275 FTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
NI +T + W P +TN++V V+ + + + D +T L G
Sbjct: 7787 VINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRK-GWQTVDTTVKDTKCTVTPLTEG 7845
Query: 1332 TEYVVSVS-------SVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR-- 1382
+ YV V+ S Y + E + L T P + D+T + W P+
Sbjct: 7846 SLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKND 7905
Query: 1383 --ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREE 1436
I Y I + + + + +T++ GTE + A N G
Sbjct: 7906 GGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPS 7965
Query: 1437 SP---LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQE 1493
P L I ++ P DL V A + I+W P E G SP+
Sbjct: 7966 EPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPP------------EKNGGSPIIG 8013
Query: 1494 FTVP----GSKSTATIS-------------GLKPGVDYTITVYAVTGRGDSPASSKPISI 1536
+ V G++ ++ G+ P +Y + V AV G S+P I
Sbjct: 8014 YHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIG----VSEPSEI 8069
Query: 1537 NYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1596
+ P D++ + I V S +R P + D+
Sbjct: 8070 SENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLT 8129
Query: 1597 MTIEGLQPTVEYVVSVYA---------QNPSGESQPLVQTAVTNIDRP-KGLAFTDVDVD 1646
M + + +E SV A +N G + + V + P K + +D+
Sbjct: 8130 MKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKS 8189
Query: 1647 SIKIAWESPQ--GQVSRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVSVV 1703
S K+ WE P+ G E G P GE + ++ L P EY V
Sbjct: 8190 SCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVK 8249
Query: 1704 ALH-----DDME-SQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPP----NVQLTGY 1752
A++ + +E P+I P P D++ T +++ W PP ++ GY
Sbjct: 8250 AVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGY 8309
Query: 1753 RV-RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTL 1811
+ ++ E+ +L P + GL +Y+ V A S P++ T
Sbjct: 8310 IIEKIAKGEERWKRCNEHLVP-ILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPT- 8367
Query: 1812 ENVSPPRRARVTDATETTI------------------TISWRTKTETITGFQVD------ 1847
+ V P +V T + TI+W I ++
Sbjct: 8368 KAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPL 8427
Query: 1848 --------------AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL-NDNA-R 1891
+P + I + K + + L+P D+ +Y+ + ND+
Sbjct: 8428 VRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRP--DHGLYMIKVENDHGIA 8485
Query: 1892 SSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPRE- 1946
+P + P N F S+L W+PP + I Y ++ + P E
Sbjct: 8486 KAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEW 8545
Query: 1947 VVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGR 1988
+V + ++T L G EY V A P + +
Sbjct: 8546 IVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSK 8587
Score = 101 bits (252), Expect = 8e-21
Identities = 253/1300 (19%), Positives = 457/1300 (35%), Gaps = 239/1300 (18%)
Query: 718 FSPLVATSESVTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTA- 772
F P T+ + + T +S ++W + G+ VE + + +E + P T
Sbjct: 17613 FKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVE--ICKADEEEWQIVTPQTGL 17670
Query: 773 --TSVNIPDLLPGRKYIVNVYQISEDG--EQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828
T I L ++Y + V +++ G E + + T + P+ +D IV
Sbjct: 17671 RVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIV 17730
Query: 829 VRW---SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYN-ITIYAVE 884
VR +R P G +P + S E + ++ GV Y ++I +
Sbjct: 17731 VRAGGSARIHIPFKGRP---TPEITWSREEGEFTDKVQ------IEKGVNYTQLSIDNCD 17781
Query: 885 ENQESTPVVIQQETTGTPRS-------DTVPSPRDLQFVEVTDVKVTIMWTPP----ESA 933
N ++ + ++G+ + DT P++L EV ++W PP +
Sbjct: 17782 RNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAK 17841
Query: 934 VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ 993
V Y +D S+ +F +V L+ G YYF+V A + P+
Sbjct: 17842 VKNYVIDKRESTRKAYANVSSKCSKTSF-KVENLTEGAIYYFRVMAENEFGVGVPVETVD 17900
Query: 994 TTKLDAP------TNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYN 1043
K P L V++T ++++ W P +++ GY V + +G +
Sbjct: 17901 AVKAAEPPSPPGKVTLTDVSQTSASLM--WEKPEHDGGSRVLGY--VVEMQPKGTEKWSI 17956
Query: 1044 VGPS-VSKYPLRNLQPASEYTVSLVAIKGNQES-PKATGV-----FTTLQPGSSIPPYNT 1096
V S V + L EY + A +S P+ GV T+QP + P+NT
Sbjct: 17957 VAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKL-PFNT 18015
Query: 1097 EVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVL 1156
+ G + E+ V+ P + +V
Sbjct: 18016 YSIQA----------------------GEDLKIEIP------VIGRPRPNISWV------ 18041
Query: 1157 RDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQ 1216
+DG+ PL T +++E + VL + + D Y +T T + G
Sbjct: 18042 KDGE------------PLKQTTRVNVEETATSTVLHI--KEGNKDDFGKYTVTATNSAGT 18087
Query: 1217 QGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFT 1276
+L +V PG PP +RF
Sbjct: 18088 ATENLSVIVLE----------KPG---------------------------PPVGPVRFD 18110
Query: 1277 NIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLP 1330
+ D + ++W PP ++N++V K + +S + + + +T L
Sbjct: 18111 EVSADFVVISWEPPAYTGGCQISNYIVE----KRDTTTTTWHMVSATVARTTIKITKLKT 18166
Query: 1331 GTEYVVSVSSVYEQHESTPLRGR-----QKTGLDSPTGIDF-SDITANSFTVHWIAP--- 1381
GTEY + + +S PL + P G F + I+ + V W P
Sbjct: 18167 GTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVND 18226
Query: 1382 -RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440
I GY + ++ + ++ P T L G EY + A E+ +
Sbjct: 18227 GGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSA-----ENIVG 18281
Query: 1441 IGQQSTVS---------DVPRDLEVVAATPTSLLISWDAPAV----TVRYYRITYGETGG 1487
IG+ S VS D P E + T ++ + W PA + Y + +
Sbjct: 18282 IGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPD 18341
Query: 1488 NSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPS 1546
++ ++ T+SGL Y V A G+ S S +I R EID P+
Sbjct: 18342 GRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPN 18401
Query: 1547 QMQVTDVQDNSI--SVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
+D + + + + + G + + G +TA + + TI+
Sbjct: 18402 ASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTL 18461
Query: 1605 TV---------EYVVSVYAQNPSG-ESQPLVQTAVTNIDRPKG-LAFTDVDVDSIKIAWE 1653
V +Y++ + N G +S P+ + P+G L T V + +AW
Sbjct: 18462 VVKDCIRTDGGQYILKL--SNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWN 18519
Query: 1654 SP----QGQVSRY--------RVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVS 1701
P +S Y R++++ + L ++ L PG+EY
Sbjct: 18520 PPLQDGGANISHYIIEKRETSRLSWTQVSTEVQAL---------NYKVTKLLPGNEYIFR 18570
Query: 1702 VVALH-----DDMESQPLIGTQSTAIPAPTDL-KFTQVTPTSLSAQWTPP----NVQLTG 1751
V+A++ + +ES P+ P P + + +T S+ W P ++ G
Sbjct: 18571 VMAVNKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEG 18630
Query: 1752 YRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVV--- 1808
Y + KE K + V+GL YE V A P++ V
Sbjct: 18631 YILEKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYR 18690
Query: 1809 --TTLENVSPPRRARVTDATETTITISWRTKT----ETITGF--QVDAVPANGQTPIQRT 1860
L PP +VTD + ++++++W + G+ +V A+ T
Sbjct: 18691 ACDALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPP 18750
Query: 1861 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAS 1900
+ +T+T L+ T+Y + +N P + S
Sbjct: 18751 TGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGS 18790
Score = 101 bits (252), Expect = 8e-21
Identities = 308/1501 (20%), Positives = 533/1501 (35%), Gaps = 204/1501 (13%)
Query: 624 NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNS--YTIKGLKPGVVYE 678
NS + W P+ S I +YIL R K S RW + ++ + + GL G YE
Sbjct: 21861 NSITLTWARPESDGGSEIQQYILERREKKST-RWVKVISKRPISETRFKVTGLTEGNEYE 21919
Query: 679 GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
+++ G + PV P P V VT+ + ++ +
Sbjct: 21920 FHVMAENAAGVGPASGIS-RLIKCREPVNP--------PGPPTVV---KVTDTSKTTVSL 21967
Query: 739 SW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQIS 794
W + G+ +E ++ GD + T + DL G +Y V I+
Sbjct: 21968 EWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAIN 22027
Query: 795 EDGEQSLILSTSQTTAPD--APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGS 852
G+ T A D P+ +D + VVR Y+ +P+ S
Sbjct: 22028 GAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWS 22087
Query: 853 STELNLPETANSVTLSDLQPGVQYNIT-------IYAVEENQESTPVVIQQETTGTPRSD 905
+ NL A+ T N VE N S + + TP
Sbjct: 22088 KPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP- 22146
Query: 906 TVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
P + F +VT T+MW P + + Y V+ + +R F
Sbjct: 22147 ----PGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIF 22202
Query: 962 AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ----TTKLDAPTNLQFVNETDSTVLVRW 1017
+V L+ GV YYF+V AV+ +P + T + P L V+ + S+ ++ W
Sbjct: 22203 -KVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAW 22261
Query: 1018 TPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEY---------- 1062
P ++ITGY L + ++G G + + + L +EY
Sbjct: 22262 LKPDHDGGSRITGYLLE--MRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDA 22319
Query: 1063 -------TVSLVAIKGNQESPKA--TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI 1113
S V IK Q P A TG+ L + P+ +V I+ PAP++
Sbjct: 22320 GYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVP-----ISGRPAPKV 22374
Query: 1114 GFKL-GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT 1172
+KL +R + T D ++ V G Y + + + + V+
Sbjct: 22375 TWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIG 22434
Query: 1173 PLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQ 1229
P T ++ +SW + +IT Y + + + V Q
Sbjct: 22435 RPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQ 22494
Query: 1230 SSCTFDNLSPGLEYNVSV-----YTVKDDKESVPISDTIIPAVPP--PTDLRFTNIGPDT 1282
T +L+ +EY+ V + V ES PI P VPP PT ++ +
Sbjct: 22495 IKVT--HLTKYMEYSFRVSSENRFGVSKPLESAPII-AEHPFVPPSAPTRPEVYHVSANA 22551
Query: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEED----VAELSISPSDNAVVLTNLLPGTE----- 1333
M + W P D + ++ Y K E + V E + + +T L+ G E
Sbjct: 22552 MSIRWEEPYH-DGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRT 22610
Query: 1334 YVVSVSSVYEQHE-STPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGY 1388
Y ++ + V + E S P+ + +D+P + +D+T ++ ++ W AP + + GY
Sbjct: 22611 YALNAAGVSKASEASRPIMAQNP--VDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGY 22668
Query: 1389 RIRHHPEHFSGRPREDRVPH---SRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS 1445
I P G R + + S N T+T L+ G Y ++A N + G +S
Sbjct: 22669 IIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNA--AGVISKGSES 22726
Query: 1446 TVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI 1505
T RD + D + + GG + G K
Sbjct: 22727 TGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLC 22786
Query: 1506 SGLKPGVDYT----ITVYAVTGRGDS---------PASSKPISINYRTEIDKP---SQMQ 1549
K + YT V R DS + +K +S+ + +D P ++
Sbjct: 22787 E--KVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV-LDSPGPCGKLT 22843
Query: 1550 VTDVQDNSISVKW-LP---SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPT 1605
V+ V ++ W LP + +T Y V + +T+ + + +EG PT
Sbjct: 22844 VSRVTQEKCTLAWSLPQEDGGAEITHYIV----------ERRETSRLNW--VIVEGECPT 22891
Query: 1606 VEYVVS-----------VYAQNPSG-----ESQPLVQTAVTNIDRPKGL-AFTDVDVDSI 1648
+ YVV+ V A N G ES+P+V I P G+ + I
Sbjct: 22892 LSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHI 22951
Query: 1649 KIAWESPQ----GQVSRYRVTYSSPED----GIHELFPAPDGEEDTAELQGLRPGSEYTV 1700
I W P+ ++S Y V + +++ + D ++ L G +Y
Sbjct: 22952 IIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYD---TRLKVTSLMEGCDYQF 23008
Query: 1701 SVVALHDDMESQP------LIGTQSTAIPAPTDL-KFTQVTPTSLSAQWTPP----NVQL 1749
V A++ S+P + + + P P + T S+S WT P +
Sbjct: 23009 RVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDI 23068
Query: 1750 TGYRVRVTPKEKTGPMK-EINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV- 1807
GY + + K+ + N ++ V L + KY V A+ S ++ +
Sbjct: 23069 VGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIA 23128
Query: 1808 -VTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPA-----NGQTPIQRTI 1861
+ +E + P + D + T+TI + P G R I
Sbjct: 23129 EIEPVERIEIP-DLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAI 23187
Query: 1862 KPDVRSYTITGLQPGTDYKIYLYTL---NDNARSSPVVIDASTAIDAP-SNLRFLATTPN 1917
SY++ + Y YT+ N + + S V+ P +++ + +
Sbjct: 23188 IDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRD 23247
Query: 1918 SLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYV 1973
S+ ++W+ P A + YI++ + + V + T I+GL GT Y V
Sbjct: 23248 SVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTV-TTKCSKTLYRISGLVEGTMYYFRV 23306
Query: 1974 I 1974
+
Sbjct: 23307 L 23307
Score = 98.2 bits (243), Expect = 8e-20
Identities = 288/1429 (20%), Positives = 523/1429 (36%), Gaps = 305/1429 (21%)
Query: 624 NSHPIQWNAPQPSHISKYILRW---RPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQ 680
N+ I+W P SK I W + +N++ KE +P +Y + GL G+ Y+ +
Sbjct: 22550 NAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFR 22609
Query: 681 LISIQQYGHQEVTRFDFTTTSTSTPVTS-NTVTGETTPFSPLVATSESVTEITASSFVVS 739
++ G + + S P+ + N V P VT++T S+ +
Sbjct: 22610 TYALNAAGVSKASE-------ASRPIMAQNPVDAPGRP---------EVTDVTRSTVSLI 22653
Query: 740 WVSAS----DTVSGFRVEYELSEEGDEPQYLDLPSTATSVN---IPDLLPGRKYIVNVYQ 792
W + + V G+ +E + E + ++L T S N + L G Y V
Sbjct: 22654 WSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLA 22713
Query: 793 ISEDGEQSLILSTSQTTAPD------APPDPTVD-QVDDTSIVVRWSRPQAPITGYRIVY 845
+ G +I S++T P APP +D ++ + +R G +V
Sbjct: 22714 KNAAG---VISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIR--------AGSDLVL 22762
Query: 846 SPSVEGS----------STELNLPETANS----------VTLSDLQPGVQYNITIYAVEE 885
+V G EL+L E + + D +Y +T+
Sbjct: 22763 DAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASG 22822
Query: 886 NQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDV 941
+ + +V ++ G TV VT K T+ W+ P+ + +T Y V+
Sbjct: 22823 TKAVSVMVKVLDSPGPCGKLTVS--------RVTQEKCTLAWSLPQEDGGAEITHYIVE- 22873
Query: 942 IPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYY-----------FKVFAVS-HGR----E 985
R SR + V G P ++Y F+V AV+ +G E
Sbjct: 22874 -----------RRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVE 22922
Query: 986 SKPLTAQQTTKLDAPTNL-QFVNETDSTVLVRWTPPRA----QITGYRLTVGLTRRGQPR 1040
S+P+ A+ + + +P + + V ++++WT P + +I+ Y V + R
Sbjct: 22923 SEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNY--LVDKREKKSLR 22980
Query: 1041 QYNVGPSVSKYPLR----NLQPASEYTVSLVAIK--GNQESPKATGVFTTLQPGSSIPPY 1094
V Y R +L +Y + A+ GN E +A+ + +P
Sbjct: 22981 WTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREP------- 23033
Query: 1095 NTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTP----GVEYV 1150
++TP P PS APR V + SI ++ P G + V
Sbjct: 23034 -----------SYTPGP---------PS----APRVVDTTKHSISLAWTKPMYDGGTDIV 23069
Query: 1151 -YTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDIT----- 1204
Y +++ QE+D +V H A T+ T PD+
Sbjct: 23070 GYVLEM----QEKDTDQWYRV----------HTNA-------TIRNTEFTVPDLKMGQKY 23108
Query: 1205 GYRITTTPTNG--QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDT 1262
+R+ G + S+ E+ ++ L+ L+ V++ + V +S
Sbjct: 23109 SFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGR 23168
Query: 1263 IIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNA 1322
PPP +TW+ IDL + + + E + L +
Sbjct: 23169 -----PPPV-------------ITWSKQ-GIDLASRAI----IDTTESYSLLIVDK---- 23201
Query: 1323 VVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR 1382
N +Y + + + +T L T P+ + +++ +S T+ W P
Sbjct: 23202 ---VNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPS-VKVKEVSRDSVTITWEIPT 23257
Query: 1383 ----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITL---TNLTPGTEYVVSIVALNGRE 1435
A + Y + E R + ++ S TL + L GT Y ++
Sbjct: 23258 IDGGAPVNNYIV----EKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLP----- 23308
Query: 1436 ESPLLIGQQSTVSD---------VPRDLEVVAATPTSLLISWDAPAVT----VRYYRITY 1482
E+ IG+ SD VP LEVV T +++ ++W+ P + Y +
Sbjct: 23309 ENIYGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEA 23368
Query: 1483 GETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEI 1542
+ G ++ T+ + T++ L G Y + A +G S ++ +
Sbjct: 23369 CKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLR 23428
Query: 1543 DKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGP------------------ 1584
P+ + ++ + +I V P+ PV P G P
Sbjct: 23429 VLPT-IDLSTMPQKTIHV---PAGRPVE----LVIPIAGRPPPAASWFFAGSKLRESERV 23480
Query: 1585 ---TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKG--LA 1639
T TK A E TI + T EY + + +N +G + ++ + + P +
Sbjct: 23481 TVETHTKVAKLTIRETTI---RDTGEYTLEL--KNVTGTTSETIKVIILDKPGPPTGPIK 23535
Query: 1640 FTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEE---DTAELQGLRPGS 1696
++D SI I+WE P+ Y + H P E T + L G+
Sbjct: 23536 IDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGN 23595
Query: 1697 EYTVSVVALH-----DDMESQPLIGTQSTAIPAPTD-LKFTQVTPTSLSAQWTPPN---- 1746
EY V A + ++S+ + S IP P + L+ V+ ++ W PP
Sbjct: 23596 EYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGG 23655
Query: 1747 VQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVS-GLMVATKYEVSVYALK---DTLTSR 1802
Q+TGY V + + +N P + + S GL +YE V A+ SR
Sbjct: 23656 SQVTGYIVE-RKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSR 23714
Query: 1803 PAQGVVTTLENVSPP---RRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQT 1855
P++ +V ++ ++PP + RVTD T T+++++W + +TG+ ++ +
Sbjct: 23715 PSKPIVA-MDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHE 23773
Query: 1856 PIQ-RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI 1903
+ T +R YT+T L G +Y+ + N P + + +
Sbjct: 23774 WTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKV 23822
Score = 97.1 bits (240), Expect = 2e-19
Identities = 340/1573 (21%), Positives = 568/1573 (36%), Gaps = 223/1573 (14%)
Query: 619 TPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
T S +S +QWN P S + Y L + +NS+ K P + GL+ GV
Sbjct: 16045 TLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGV 16104
Query: 676 VYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASS 735
YE ++ + G P + P P E++ +T +S
Sbjct: 16105 EYEFRVSAENIVG-------------IGKPSKVSECYVARDPCDP-PGRPEAII-VTRNS 16149
Query: 736 FVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVY 791
+ W ++G+ VE + EG + T + L+ +Y V
Sbjct: 16150 VTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVI 16209
Query: 792 QISEDGEQSLIL-STSQTTAPDA--PPDPTVDQVDDTSIVVRWS---RPQAPITGYRIVY 845
+ G S ST TA D PP ++D +IVV + A I G I
Sbjct: 16210 ARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPI-- 16267
Query: 846 SPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
P+++ + L TA + +D + + +S +++ + RS
Sbjct: 16268 -PTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV-----DSGNYILKAKNVAGERS 16321
Query: 905 DTV-------PSPRDLQFV--EVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP 955
TV P P + V VT K T+ W PP + D+I + RL
Sbjct: 16322 VTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPP---LQDGGSDIINYIVERRETSRLV 16378
Query: 956 IS------RNTFAEVTGLSPGVTYYFKVFAVS-----HGRESKPLTAQQTTKL-DAPTNL 1003
+ + +VT L G Y F++ AV+ ES+P+ A+ + DAP
Sbjct: 16379 WTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAP 16438
Query: 1004 QFVNETDSTVLVRWTPPRA----QITGYRLTV----GLTRRGQPRQYNVGPSVSKYPLRN 1055
+ T +++V W P + +I GY L G+ R + + +G +
Sbjct: 16439 EVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGI-RWTRCHKRLIGELRLRVTGLI 16497
Query: 1056 LQPASEYTVSLVAIKGNQE-SPKAT---GVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
E+ VS G E SP + +PG P ++T +++ ++W+
Sbjct: 16498 ENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPI 16557
Query: 1112 RIGF---------KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD---G 1159
G K V + + +I V L EY + I + G
Sbjct: 16558 YDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVG 16617
Query: 1160 QERDAPIVNKVVTPL-SPPTNLHLEANPDTGV-------LTVSWERSTTPDITGYRITTT 1211
+ D P V L +P +L LE + L V + TP++ ++
Sbjct: 16618 EHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKV--- 16674
Query: 1212 PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV----KDDKESVPISDTIIPAV 1267
+G+ ++ V + +S DN++ Y+ YT+ +S ++ ++
Sbjct: 16675 --DGEIRDAAIIDVTSSFTSLVLDNVN---RYDSGKYTLTLENSSGTKSAFVTVRVLDTP 16729
Query: 1268 PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAELSISPSDNAVV 1324
PP +L+ T I D++ +TW PP +D + + Y K E + A + + N+
Sbjct: 16730 SPPVNLKVTEITKDSVSITW-EPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWK 16788
Query: 1325 LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL----DSPTGIDFSDITANSFTVHWIA 1380
+ L G Y V++ E P + + P I D+T NS ++ W
Sbjct: 16789 IDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTK 16848
Query: 1381 PR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436
P + I Y + +H RV + +TNLT G EY+ +VA+N +
Sbjct: 16849 PEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQ--AVITNLTQGEEYLFRVVAVNEKGR 16906
Query: 1437 S-PLLIGQQSTVSDVPRDLEVVAA-TPTSLLISWD----APAVTVRYYRITYGETGGNSP 1490
S P + D+ + +V A + S+ + D P IT+ + G P
Sbjct: 16907 SDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDG--LP 16964
Query: 1491 VQEFT---VPGSKSTATIS----GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
+++ T V S T+S G Y ITV V G+ K SI T +D
Sbjct: 16965 LKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQ-------KTASIEIVT-LD 17016
Query: 1544 KP----SQMQVTDVQDNSISVKWLP----SSSPVTGYRV-----TTTPKNGPGPTKTKTA 1590
KP ++ DV SI++ W P +T Y V TTT + T +T
Sbjct: 17017 KPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTT 17076
Query: 1591 GPDQTEMTIEGLQPTVEYVVSVYAQNPSG-----ESQPLVQTAVTNIDRPKGLAF-TDVD 1644
+ + L+ EY ++A+N G ES P+V P G F T +
Sbjct: 17077 ------LKVTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAIS 17130
Query: 1645 VDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE---EDTA-ELQGLRPGSEYTV 1700
DS+ I W P + Y + + + DT + Q L G EY
Sbjct: 17131 KDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEF 17190
Query: 1701 SVVALHDDMESQPLIGTQSTAIPAPTDLKFT----QVTPTSLSAQWTPP----NVQLTGY 1752
V A + + ++ P D T V ++ QWT P +TGY
Sbjct: 17191 RVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGY 17250
Query: 1753 RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT-LTSRPAQ--GVVT 1809
V MK + VSGL +YE V A S+P+ G +T
Sbjct: 17251 IVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPIT 17310
Query: 1810 TLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYT 1869
+ V PR + +T + + T F+++A P ++ D
Sbjct: 17311 AKDEVELPRISMDPKFRDTIVVNAGET-------FRLEADVHGKPLPTIEWLRGDKEIEE 17363
Query: 1870 ITGLQ-PGTDYKIYL------------YTLNDN----ARSSPV---VIDASTAIDAPSNL 1909
+ TD+K L Y L + ++S PV V+D + P +
Sbjct: 17364 SARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGP--V 17421
Query: 1910 RFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEP 1965
+ T ++W PP + I+ Y+++ ++ S V +T L
Sbjct: 17422 QVTGVTSEKCSLTWSPPLQDGGSDISHYVVE-KRETSRLAWTVVASEVVTNSLKVTKLLE 17480
Query: 1966 GTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTH 2025
G EY ++A+ EPL + P L+ P P+ L+V + + + V
Sbjct: 17481 GNEYVFRIMAVNKYGVGEPL------ESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCW 17534
Query: 2026 PGYDTGNGIQLPG 2038
D+ G ++ G
Sbjct: 17535 NRPDSDGGSEIIG 17547
Score = 94.0 bits (232), Expect = 2e-18
Identities = 154/662 (23%), Positives = 253/662 (38%), Gaps = 93/662 (14%)
Query: 1447 VSDVP---RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
V DVP R+LEV + ++W+ P I Y + + + + ++ +
Sbjct: 6781 VIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAES 6840
Query: 1504 ---TISGL-KPGVDYTITVYAVT--GRGDSPASSKPISINYRTEIDKPS-QMQVTDVQDN 1556
T++GL K GV+Y V A G G+ + P+ + ++ P + +TDV
Sbjct: 6841 CEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRF 6900
Query: 1557 SISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV 1612
+S+ W P + +T Y + K T + T+ + EY V
Sbjct: 6901 GVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRV 6960
Query: 1613 YAQNPSGESQPLVQTAVTN----IDRPK---GLAFTDVDVDSIKIAWESPQGQVSRYRVT 1665
AQN G +P T I+RP L +D S+++ WE P +
Sbjct: 6961 RAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILG 7020
Query: 1666 Y--SSPEDGIH-------ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIG 1716
Y E+G +L P E T ++ GL G++Y V A + S P
Sbjct: 7021 YIIERCEEGKDNWIRCNMKLVP-----ELTYKVTGLEKGNKYLYRVSAENKAGVSDP--- 7072
Query: 1717 TQSTAIPAPTDLKFTQVTPT-SLSA-----QWTPPN-----VQLTGY-RVRVT-----PK 1759
+ I P V PT LSA + PN V TGY R T
Sbjct: 7073 ---SEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKV 7129
Query: 1760 EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPP 1817
+TG ++ + +V+S + + + +Y LK + G V + S P
Sbjct: 7130 LETGDRVKMKTLSAYAELVISP---SERSDKGIYTLKLENRVKTISGEIDVNVIARPSAP 7186
Query: 1818 RRARVTDATETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGL 1873
+ + D T+ ++ ++W + +TG+ V+ + +T + +T+ L
Sbjct: 7187 KELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDL 7246
Query: 1874 QPGTDYKIYLYTLNDNARSSPVVIDA-------STAIDAPSNLRFLATTPNSLLVSWQPP 1926
G +Y + N P +D +T D P N+++ T NS+ ++W PP
Sbjct: 7247 VQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPP 7306
Query: 1927 R----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 1982
+ +RI GYI++ GS P T+ +TGLE G Y V AL S
Sbjct: 7307 KNDGGSRIKGYIVERCPRGSDKWVACGEP-VAETKMEVTGLEEGKWYAYRVKALNRQGAS 7365
Query: 1983 EPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQ 2042
+P + T+E+ + T P + LDV T G I+LP T
Sbjct: 7366 KP---SRPTEEIQAVDTQEAPEI----FLDVKLLAGLT-------VKAGTKIELPATVTG 7411
Query: 2043 QP 2044
+P
Sbjct: 7412 KP 7413
Score = 94.0 bits (232), Expect = 2e-18
Identities = 327/1598 (20%), Positives = 576/1598 (36%), Gaps = 255/1598 (15%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W+ P+ S I+ +I+ R + W++ I + I GL G Y+ ++I+
Sbjct: 8910 LNWSDPEDDGGSEITGFIIE-RKDAKMHTWRQP-IETERSKCDITGLLEGQEYKFRVIAK 8967
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV--- 741
++G PV + P + TE T S+ + W
Sbjct: 8968 NKFG-------------CGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPR 9014
Query: 742 -SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQS 800
+ + G+ +E ++ D + TS + +L + Y V ++E GE
Sbjct: 9015 SNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESE 9074
Query: 801 LILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWSRP---QAPITGYRIVYSPSVEGSST 854
L + D P PT+ V +I V+ P A +TG + P +E S
Sbjct: 9075 PSLPLNVVIQDDEVP-PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPM---PKIEWSKN 9130
Query: 855 E--LNLPETANSVTLSDLQPG-VQYNITI-YAVEENQESTPVVIQQETTGTPRS------ 904
E + P A +T ++ + ++I AV E++ + V R+
Sbjct: 9131 ETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVY 9190
Query: 905 DTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
D PR+L ++ + W P S +T Y +D + + + NT
Sbjct: 9191 DRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVT---NT 9247
Query: 961 FAE----VTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKLDAPTNL-QFVNETD 1010
E + L P Y F+V + +S +S + Q +L P + + T
Sbjct: 9248 AVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTK 9307
Query: 1011 STVLVRWTPP----RAQITGYRLTVGLTRRGQPRQY----------NVGPSVSKYPLRNL 1056
++LV WTPP + ITGY L +R + Y VG ++ + L
Sbjct: 9308 GSMLVSWTPPLDNGGSPITGY----WLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRL 9363
Query: 1057 QPASEYTVSLVAIKG------NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
+Y +AI ++ S PG P + T+++I + W P
Sbjct: 9364 LEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPP 9423
Query: 1111 PRIGFKLGVRPSQG--GEAPREVTSD------------SGSIVVSGLTPGVEYVYTIQVL 1156
K G P +G E E T+D + VV L +Y + ++ +
Sbjct: 9424 A----KDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAV 9479
Query: 1157 RD-GQERDAPIVNKV-VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT- 1213
+ G+ + ++ T + + ++ ++ + + P + R T +
Sbjct: 9480 NEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSW 9539
Query: 1214 --NGQQGNSLEEVVH---ADQSSCTFDNLSPGL----------EYNVSVYTVKDDKESVP 1258
+G+ ++++ VH D T +N S + +Y+++ K +++
Sbjct: 9540 EFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKN-KAGQKTAN 9598
Query: 1259 ISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEED-VAELSIS 1317
++ PP DL+ ++I + R++W P D + + Y K D A ++
Sbjct: 9599 CRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDD-DGGDRIKGYVIEKRTIDGKAWTKVN 9657
Query: 1318 P--SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL-------DSPTGIDFSD 1368
P V+ +LL +Y V + P+ Q+T D P +
Sbjct: 9658 PDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGL 9717
Query: 1369 ITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRED-RVPHSRN----SITLTNLT 1419
IT N+ + W P+ + +T Y + +G +E R + R+ T+ +L
Sbjct: 9718 ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLV 9777
Query: 1420 PGTEYVVSIVALN--GREESPLLIG-------QQSTVSDVPRDLEVVAATPTSLLIS-WD 1469
G EY + A+N G + +G D+ +EV T +++
Sbjct: 9778 EGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKG 9837
Query: 1470 APAVTVRYYRITYGETGGNSPVQEFT-----VPGSKSTATISGLKPGVDYTITVYAVTGR 1524
P T+ +++ + PV T V T I + T+ AV
Sbjct: 9838 VPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNL 9897
Query: 1525 GDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPK 1579
G +SK + +N P ++ V + +++ W P S +T Y +
Sbjct: 9898 G---TASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREA 9954
Query: 1580 NGPGPTKT---KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT--NI-- 1632
N KT ++ P + TI L EYV + AQN G +PL T N+
Sbjct: 9955 N----RKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFS 10010
Query: 1633 --DRPKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDT 1686
P + V +S+ + WE P+ V+ Y + +D + + + +
Sbjct: 10011 VPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGY---WLEMKDTTSKRWKRVNRDPIK 10067
Query: 1687 A-------ELQGLRPGSEYTVSVVALH------DDMESQPLIGTQSTAIPAPTDLKFTQV 1733
A ++ GL GS+Y V A++ + S P A P P K T
Sbjct: 10068 AMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDW 10127
Query: 1734 TPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 1789
T +S +W+PP ++TGY V + K K + + +VV+GL Y+
Sbjct: 10128 TKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYK 10187
Query: 1790 VSVYALKDTLTSRPAQGVVTTLEN----VSPPRR--ARVTD----------------ATE 1827
V A+ P + V +E VSP + A V D + +
Sbjct: 10188 FRVRAVNIAGIGEPGE-VTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGK 10246
Query: 1828 TTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDV--RSYTITGLQPGTDYKIYLYT 1885
T++W T+ P + TI+ S I Q L
Sbjct: 10247 PPPTVTWNMNERTL--------------PQEATIETTAISSSMVIKNCQRSHQGVYSLLA 10292
Query: 1886 LNDNARSSPVVIDASTAIDAPSNLRFLA--TTPNSLLVSWQPPR----ARITGYIIKYEK 1939
N+ +I + P FLA T S ++W P + IT Y+I EK
Sbjct: 10293 KNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVI--EK 10350
Query: 1940 PGSPPREVVPRPRPGVTE-ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLV 1998
S R P + AT+ GL G Y + IA +N+ P + + + + +
Sbjct: 10351 RESDRRAWTPVTYTVTRQNATVQGLIQGKAY-FFRIAAENSIGMGPFVETSEALVIREPI 10409
Query: 1999 TLPHPNLHGPEILDVPSTVQKTPFVT--HPGYDTGNGI 2034
T+P PE L+V + T +T P YD G+ I
Sbjct: 10410 TVP----ERPEDLEVKEVTKNTVTLTWNPPKYDGGSEI 10443
Score = 94.0 bits (232), Expect = 2e-18
Identities = 304/1555 (19%), Positives = 549/1555 (35%), Gaps = 206/1555 (13%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W P S I+ Y+L R +V K P + GL+ G YE ++ +I
Sbjct: 13201 VSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAI 13260
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW---- 740
+ G + + S + P V + T SS +SW
Sbjct: 13261 NKAGPGKPSD------------ASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPA 13308
Query: 741 VSASDTVSGFRVEYELSEEGDEPQYLDLPST--ATSVNIPDLLPGRKYIVNVYQISEDGE 798
+ G+ VE + + + D +LP T + L+ +Y VY +++ G
Sbjct: 13309 YDGGSPIIGYLVEVKRA-DSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIG- 13366
Query: 799 QSLILSTSQTTAPD--------APPDPTVDQVDDTSIVVR---WSRPQAPITGYRIVYSP 847
+ + PD PP+ +D ++++R R P+ G P
Sbjct: 13367 -----YSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRP---PP 13418
Query: 848 SVEGSSTELNLPETAN-SVTLSDLQPGV-----------QYNITIYAVEENQESTPVVIQ 895
+ S +NL + + +D + +Y +T+ +E T VV
Sbjct: 13419 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13478
Query: 896 QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHG 951
+T G P + TV E++ + W PP S + Y V
Sbjct: 13479 LDTPGPPVNVTVK--------EISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWST 13530
Query: 952 QRLPISRNTFAEVTGLSPGVTYYFKVFAVSH---GRESKPLTAQQTTKLDAP-TNLQFVN 1007
S+ +F V L G +Y+F+VFA + G + A + ++ P +L+ +
Sbjct: 13531 VTTECSKTSF-RVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRS 13589
Query: 1008 ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYT 1063
+ S+ + W P ++I GY + LT + ++ S+ +Y ++L EYT
Sbjct: 13590 VSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMKSLSL-QYSAKDLTEGKEYT 13647
Query: 1064 VSLVAIKGNQE-SPKATGVFT---TLQPG---SSIPPYNTEVTETT-----IVITWTPAP 1111
+ A N E +P V + P +P E + I I PAP
Sbjct: 13648 FRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAP 13707
Query: 1112 RIGFKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
+ +K G P + E ++ + +++V YTI + ++ I KV
Sbjct: 13708 SVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKV 13767
Query: 1171 VTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
V PT +T+ W + +IT Y + + + + V
Sbjct: 13768 VGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAV-- 13825
Query: 1228 DQSSCTFDNLSPGLEYNVSV-----YTVKDDKESVPI---SDTIIPAVPPPTDLRFTNIG 1279
+++ L G+EY V Y V + +S PI +P PPP ++ ++
Sbjct: 13826 QKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNI--VDVR 13883
Query: 1280 PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVA-----ELSISPSDNAVVLTNLLPGTEY 1334
D++ +TW P + + K + + I D V T L G EY
Sbjct: 13884 HDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV--TGLTEGLEY 13941
Query: 1335 VVSVSSVYEQHESTPLRGRQKT----GLDSPTGIDFSDITANSFTVHWIAPR----ATIT 1386
V ++ P + +D P + +IT NS T+ W P+ +T
Sbjct: 13942 EFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLT 14001
Query: 1387 GYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN--GREESPLLIGQQ 1444
GY + + + V + T+T+L G +Y I A N G +P +
Sbjct: 14002 GYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAP----SE 14057
Query: 1445 STVSDVPRDLEVVAATPTSLLISWDAPAVTVR----------------YYRITYGETGGN 1488
ST + + +D PT +L +T++ + ++ + G +
Sbjct: 14058 STETIICKD---EYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKD 14114
Query: 1489 SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQM 1548
+ T S T+++ +K Y +T + + + P +
Sbjct: 14115 IRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPV 14174
Query: 1549 QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
++++V ++ W P SP+ Y + + T + + +Q
Sbjct: 14175 EISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQG 14234
Query: 1605 TVEYVVSVYAQNPSGESQPLVQTAVTNIDR------PKGLAFTDVDVDSIKIAWESP--- 1655
EY+ V A N G+ +P+ V +DR P+ ++V ++ ++W+ P
Sbjct: 14235 N-EYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDD 14293
Query: 1656 -QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVA-----LHDDM 1709
+++ Y V + + ++ GL+ GS Y V A +
Sbjct: 14294 GGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPS 14353
Query: 1710 ESQPLIGTQSTAIP--APTDLKFTQVTPTSLSAQWTPPN----VQLTGYRVRVTPKEKTG 1763
E+ + + A P P++ T T S S W P+ +++TGY V +K G
Sbjct: 14354 EASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGY---VVEHQKVG 14410
Query: 1764 PMKEI----NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRR 1819
I A + VV L KY + A+ D PA V+ +E V
Sbjct: 14411 DEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPA--VIPDVEIVEREMA 14468
Query: 1820 ARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIK-------PDVRSYTITG 1872
E T+ R + PA T + I + S+T+
Sbjct: 14469 PDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTLLI 14528
Query: 1873 LQPGTDYKI--YLYTLNDNARSSPVVIDASTAIDAPS---NLRFLATTPNSLLVSWQPP- 1926
+ Y ++ T+ + A ++ +D P NLR T +S+ + W P
Sbjct: 14529 IPECNRYDTGKFVMTIENPAGKKSGFVNV-RVLDTPGPVLNLRPTDITKDSVTLHWDLPL 14587
Query: 1927 ---RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 1983
+RIT YI++ ++ + + +TGL G EY V+A E
Sbjct: 14588 IDGGSRITNYIVE-KREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGE 14646
Query: 1984 PLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPG 2038
P +T E + P P P+ L++ + T + P G ++ G
Sbjct: 14647 P----TETTEPVKASEAPSP----PDSLNIMDITKSTVSLAWPKPKHDGGSKITG 14693
Score = 93.6 bits (231), Expect = 2e-18
Identities = 287/1440 (19%), Positives = 522/1440 (36%), Gaps = 175/1440 (12%)
Query: 675 VVYEGQLISIQQYGHQEVTRFDFTTTSTS--TPVTSNTVTGETT--PFSPLVATSESVTE 730
+ E I++++ + R++ T ++S T N V + P P+V +++
Sbjct: 20222 ITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVV-----ISD 20276
Query: 731 ITASSFVVSWVSAS-DTVSGFRVEYELSEEGDEPQYLDLPSTA--TSVNIPDLLPGRKY- 786
IT S + W D S L E + ++ +T T + + L G +Y
Sbjct: 20277 ITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQ 20336
Query: 787 ----IVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYR 842
N + IS+ + + + T P P P V V SI V W P + G
Sbjct: 20337 FRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVS--NGGS 20394
Query: 843 IVYSPSVEGSSTELNLPETANSVTL-------SDLQPGVQYNITIYAVEENQESTPVVIQ 895
V +E L + AN + + + + G+ Y +YA P
Sbjct: 20395 AVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKP---S 20451
Query: 896 QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHG 951
+ D PR+++ +++ V++ W P S +TGY V+ +LP
Sbjct: 20452 HPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVE--RRDLPDGRW 20509
Query: 952 QRLPISRNTFAE--VTGLSPGVTYYFKVFAVSH-GRESKPL-TAQQTTKLDAPTNLQFVN 1007
+ + T + ++GL+ Y F+VFA + G S P T +D+
Sbjct: 20510 TKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDL 20569
Query: 1008 ETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--RQYNVGPSVSKYPLRNLQPASEYTVS 1065
+ T +V++ T +L G++ + P Y + L ++ ++
Sbjct: 20570 PLEYTEVVKYRAG----TSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASI 20625
Query: 1066 LV-------------AIKGNQESPKATGVFTTL-QPGSSIPPYNTE-VTETTIVITW-TP 1109
L+ ++ S AT L +PG P + VT I + W P
Sbjct: 20626 LIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPP 20685
Query: 1110 APRIGFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQVLR-----D 1158
A G K+ + E R V S + I + + G EY++ ++ + +
Sbjct: 20686 ADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGE 20745
Query: 1159 GQERDAPIV-NKVVTPLSP--PTNLHLEANPDTGVLTVSWERSTT---PDITGYRITTTP 1212
E D+ + N VTP P P + N +TV W R DI+GY +
Sbjct: 20746 PLESDSVVAKNAFVTPGPPGIPEVTKITKNS----MTVVWSRPIADGGSDISGYFLEKRD 20801
Query: 1213 TNGQQG-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV--------KDDKESVPISDTI 1263
L+E + + T L+ +Y V V + E +D I
Sbjct: 20802 KKSLGWFKVLKETIRDTRQKVT--GLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPI 20859
Query: 1264 IPAVPPPTDLRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEE-DVAELSISPS 1319
P PP +R + ++ + W+ P +T ++V + EE
Sbjct: 20860 DPP-GPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVR 20918
Query: 1320 DNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ----KTGLDSPTGIDFSDITANSFT 1375
V++NL PG Y VS+V + P+ + K L++P ID S
Sbjct: 20919 TTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPE-IDLDVALRTSVI 20977
Query: 1376 VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSI---------TLTNLTPGT--EY 1424
+ ++ R P + ++ +R SI T+ +T +Y
Sbjct: 20978 AKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKY 21037
Query: 1425 VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1484
+++I G +S + + + L+V + ++ + WD P + I Y
Sbjct: 21038 ILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 21097
Query: 1485 TGGNSPVQEFTVPGSKSTATISGL-----KPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
++ + ++V K ++T L K + + G G+ +++P+
Sbjct: 21098 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVK---A 21154
Query: 1540 TEIDKP-SQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594
E+ P + + D S+ + W S +T Y V + G G AG +
Sbjct: 21155 AEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVV---ERKGKGEQTWSHAGISK 21211
Query: 1595 T-EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFT-DVDVDSIKIAW 1652
T E+ + L+ V+A+N G S P+ +T K L T +VD+ I A
Sbjct: 21212 TCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPIT----VKELIITPEVDLSDIPGAQ 21267
Query: 1653 ESPQ-GQVSRYRVTY-SSPEDGIHEL---FPAPDGE-------EDTAELQGLRPGSEYTV 1700
+ + G + Y P+ I L P + E E+ L E+
Sbjct: 21268 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGG 21327
Query: 1701 SVVALHDDMESQPLIGTQSTAIPAPT----DLKFTQVTPTSLSAQWTPP----NVQLTGY 1752
+ D+ + + + P+ ++F ++ S+ W P ++T Y
Sbjct: 21328 KYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCY 21387
Query: 1753 RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLE 1812
+ +T K + + ++ V L+ +Y+ V A S+P + +
Sbjct: 21388 SIEKRETSQTN-WKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAK 21446
Query: 1813 N----VSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKP- 1863
+ PP + + + T ++++W +TGF V+ N + P
Sbjct: 21447 HQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPI 21506
Query: 1864 DVRSYTITGLQPGTDYKIYLYTLNDNARSSP----VVIDASTAIDAPSNLRFLATTPNSL 1919
R Y TGL G DY+ +Y N SSP A + +D P ++ T ++
Sbjct: 21507 SGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETI 21566
Query: 1920 LVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 1975
+ W PP ++I GY I+ ++ G+ + T+TGL PG Y +IA
Sbjct: 21567 TLKWNPPLRDGGSKIVGYSIE-KRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIA 21625
Score = 91.3 bits (225), Expect = 1e-17
Identities = 329/1588 (20%), Positives = 528/1588 (33%), Gaps = 253/1588 (15%)
Query: 589 CYGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPK 648
C R GE+ S + V + + + P P PI P H++ + W+P
Sbjct: 11268 CLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTG-PINILDVTPEHMT---ISWQPP 11323
Query: 649 NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQL-----ISIQQYGHQEVTRFDFTTTSTS 703
G I + + GVV G I Q G + V R
Sbjct: 11324 KDDGG--SPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGV 11381
Query: 704 TPVTSNTVTGETTPFSPLVATSESV-TEITASSFVVSWV----SASDTVSGFRVEYELSE 758
P +T T FSP + V T+IT ++ VSW ++G+ +E
Sbjct: 11382 GPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERR-EV 11440
Query: 759 EGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTA--PDAPPD 816
G + P + L G Y V+ + G S+ A P PP
Sbjct: 11441 TGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPG 11500
Query: 817 PTV-----DQVDDTSIVVRWSRPQA----PITGYRIVYSPSVEGSSTELNLPETANSVT- 866
P + D+ +T+ +V W++P + PI GY + +N E
Sbjct: 11501 PPINPKLKDKSRETADLV-WTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQCAF 11559
Query: 867 -LSDLQPGVQYNITIYAVE-----ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTD 920
+ L G +Y I A E +E VI ++ P + + RD+ V V
Sbjct: 11560 RVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRVGQ 11619
Query: 921 V-----------KVTIMWTPPESA-VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLS 968
+ I WT V RVD+I Q LP E
Sbjct: 11620 TIRILARVKGRPEPDITWTKEGKVLVREKRVDLI---------QDLPRVELQIKEAVRAD 11670
Query: 969 PGVTYYFKVFAVSHGRESKPLTAQQTTKLDAP---TNLQFVNETDSTVLVRWTPPRAQIT 1025
G + H + S + LD P NL+ N T + W P
Sbjct: 11671 HGKYIISAKNSSGHAQGSAIVNV-----LDRPGPCQNLKVTNVTKENCTISWENPLDN-G 11724
Query: 1026 GYRLTVGLTRRGQPRQYN---VGPSVSKYPLR-NLQPASEYTVSLVAIKGNQESPKATGV 1081
G +T + +P Q V V+K ++ NL +EY + A GV
Sbjct: 11725 GSEITNFIVEYRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCA-------ENKVGV 11777
Query: 1082 FTTLQPGSSI----------PPYNTEVTE---TTIVITWTP------APRIGFKLG--VR 1120
T++ + I P N + + T + + W +P + + + ++
Sbjct: 11778 GPTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLK 11837
Query: 1121 PSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP---LSPP 1177
S E + + +V Y + +Q +G E D +VV P
Sbjct: 11838 GSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPV 11897
Query: 1178 TNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNL 1237
+L L +GVLTV G I G +G EV T
Sbjct: 11898 LDLKL-----SGVLTVK---------AGDTIRLEA--GVRGKPFPEVAWTKDKDATDLTR 11941
Query: 1238 SPGLEYNVSVYTVKDDKESVPISD---------------------TIIPAVPPPTDLRFT 1276
SP ++ + + K SD ++ P +L+
Sbjct: 11942 SPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIV 12001
Query: 1277 NIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTE 1333
++ D V W PP ++ N+++ K + S + +T L+ G E
Sbjct: 12002 DVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMV-WSTYSATVLTPGTTVTRLIEGNE 12060
Query: 1334 YVVSVSSVYEQHESTPLRGRQ---KTGLDSPTGIDFSDITANS---FTVHWIAPR----A 1383
Y+ V + + P + KT D P D ++T S TV W P
Sbjct: 12061 YIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGK 12120
Query: 1384 TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN-------GREE 1436
+ITGY + +H + ++ + + NL P EY + A N
Sbjct: 12121 SITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPS 12180
Query: 1437 SPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP-----AVTVRYYRITYGETGGNSPV 1491
P++ P + VV T S+ + W P A + Y + SP
Sbjct: 12181 RPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPD 12240
Query: 1492 QEFTVPGS-----KSTATISGLKPGVDYTITVYAVTGRG-DSPASSKPISINYRTEIDKP 1545
+ + + + T++ L +Y V A G PA K E KP
Sbjct: 12241 EGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELK--------EAIKP 12292
Query: 1546 SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKT-KTAGPDQTEMTIE-GLQ 1603
++ D S++ L R+ + P P T + G D + L
Sbjct: 12293 KEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLV 12352
Query: 1604 PTVEYVV------------SVYAQNPSGESQPLVQTAVTNIDRP-KGLAFTDVDVDSIKI 1650
T+ ++V S+ NP+GE V V + P L +DV S +
Sbjct: 12353 DTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHV 12412
Query: 1651 AWESPQG----QVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH 1706
+W P+ QV+ Y V + P+ ++ + + L PG+EY V A++
Sbjct: 12413 SWAPPENDGGSQVTHYIVEKREADRKTWSTV-TPEVKKTSFHVTNLVPGNEYYFRVTAVN 12471
Query: 1707 D-------DMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP--------NVQLTG 1751
+ D+ L + P L+ T++T S + W PP + +T
Sbjct: 12472 EYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITS 12531
Query: 1752 YRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP--AQGVVT 1809
YR P ++ E ++ D S +VV+GL KY+ V A S P A+GV
Sbjct: 12532 YREEEQPADR---WTEYSVVKDLS-LVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYE 12587
Query: 1810 TLENVSPPRRARVTDAT---------------ETTITISWRT-KTETITGFQVDAVPANG 1853
E + PP+ T + T W+ + E +T + A+
Sbjct: 12588 AKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADS 12647
Query: 1854 QTP--IQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRF 1911
+ I+ + D Y++T D + VV+DA P ++
Sbjct: 12648 SSILIIKDVTRKDSGYYSLTAENSSG---------TDTQKIKVVVMDAPGPPQPPFDISD 12698
Query: 1912 LATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGT 1967
+ SL SW P + IT YI++ + S V T + L PG
Sbjct: 12699 IDADACSL--SWHIPLEDGGSNITNYIVE-KCDVSRGDWVTALASVTKTSCRVGKLIPGQ 12755
Query: 1968 EYTIYVIALKNNQKSEPLIGRKKTDELP 1995
EY V A SEPL K + P
Sbjct: 12756 EYIFRVRAENRFGISEPLTSPKMVAQFP 12783
Score = 90.9 bits (224), Expect = 1e-17
Identities = 273/1318 (20%), Positives = 459/1318 (34%), Gaps = 189/1318 (14%)
Query: 771 TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP---DPTVDQVDDTSI 827
++TS + DL + V +E G +T A + P D ++ TS+
Sbjct: 21115 SSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSV 21174
Query: 828 VVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAV 883
++ W++P + IT Y + E + + + +T + +S L+ ++A
Sbjct: 21175 ILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTCE-IEVSQLKEQSVLEFRVFAK 21233
Query: 884 EENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIP 943
E S PV I T + + +P ++ ++ +VT+ Y+ P
Sbjct: 21234 NEKGLSDPVTIGPITV----KELIITP-EVDLSDIPGAQVTVRIGHNVHLELPYKGKPKP 21288
Query: 944 VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN- 1002
+ G LP+ + F + +T K HG + + ++ P
Sbjct: 21289 SISWLKDG--LPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITV 21346
Query: 1003 ------------LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP 1046
++F +V++ W P +IT Y + T + +
Sbjct: 21347 ITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSV 21406
Query: 1047 SVSKYPLRNLQPASEYTVSLVAI-KGNQESPKATGVFTTLQ----PGSSIPPYNTEVTET 1101
+ + + + NL +EY + A + P + + PG P VT
Sbjct: 21407 ARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSD 21466
Query: 1102 TIVITWTP------APRIGFKLGVRPSQGGEAPREVTSD-SG-SIVVSGLTPGVEYVYTI 1153
+ +TW + GF + + + TS SG +GL G++Y + +
Sbjct: 21467 GMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRV 21526
Query: 1154 QVLRDG---QERDAPIVNKVVTPLSPP-TNLHLEANPDTGVLTVSWE---RSTTPDITGY 1206
D V+P+ PP T +++ +T +T+ W R I GY
Sbjct: 21527 YAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRET--ITLKWNPPLRDGGSKIVGY 21584
Query: 1207 RITTTPTNGQQGNSL-EEVVHADQSSC--TFDNLSPGLEYNV------SVYTVKDDKESV 1257
I +QGN D S C T LSPG Y +V T+ +S
Sbjct: 21585 SIEK-----RQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSS 21639
Query: 1258 PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAEL 1314
I T VPP GP+ LV+ PV +D E+
Sbjct: 21640 GIIMTRDENVPP-----IVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEI 21694
Query: 1315 SISPSDNAVVLTNLLPGTEYVV--------SVSSVYEQHESTPLRGRQKTGLDSPTG--- 1363
+ + +T++L T V V +V ++ S + K + G
Sbjct: 21695 EKRMN---MEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVV 21751
Query: 1364 --IDFSDITANSFTVHWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLT 1416
I F++IT T+ W AP A IT Y I + + ED+ S T
Sbjct: 21752 GPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC--EAQSYTAI 21809
Query: 1417 NLTPGTEYVVSIVALN----GR--EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
L G EY + A+N GR + P++ Q TV D P E T S+ ++W
Sbjct: 21810 KLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWAR 21869
Query: 1471 PAVTVRYYRITYGETGGNSPVQEFTV-----------------PGSKSTATISGLKPGVD 1513
P E+ G S +Q++ + P S++ ++GL G +
Sbjct: 21870 P------------ESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNE 21917
Query: 1514 YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ---MQVTDVQDNSISVKW----LPSS 1566
Y V A G PAS I R ++ P ++VTD ++S++W
Sbjct: 21918 YEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGG 21977
Query: 1567 SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ 1626
+ GY + + K +T T+ LQ EY V A N +G+
Sbjct: 21978 MEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEV 22037
Query: 1627 TA-VTNIDRPKGLAFTDVDVDS-IKIAWESPQGQVSRYRVTY----------SSPEDGIH 1674
T + +DR L ++D+D+ K G R + Y S P+ +
Sbjct: 22038 TGTIKAVDR---LTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLS 22094
Query: 1675 ---ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFT 1731
++ T E +YT++V + T P P + F
Sbjct: 22095 LRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP-PGPITFK 22153
Query: 1732 QVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE----INLAPDSSSVVVSGLMVATK 1787
VT S + W P + G R+ EK + I+ V+ L
Sbjct: 22154 DVTRGSATLMWDAPLLD-GGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVP 22212
Query: 1788 YEVSVYALKDTLTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISW----RTKTETI 1841
Y V A+ + P + + E +PPRR V D ++++ ++W I
Sbjct: 22213 YYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRI 22272
Query: 1842 TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1901
TG+ ++ ++ + ++T+ L T+Y+ + ND S P +S
Sbjct: 22273 TGYLLEMRQKGSDFWVEAGHTKQL-TFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSV 22331
Query: 1902 AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP---RPRPGVT 1956
I P P + L IT +I K GSP VP RP P VT
Sbjct: 22332 IIKEPQ------IEPTADLTG-------ITNQLITC-KAGSPFTIDVPISGRPAPKVT 22375
Score = 90.1 bits (222), Expect = 2e-17
Identities = 343/1758 (19%), Positives = 611/1758 (34%), Gaps = 294/1758 (16%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W P S I YI+ R + + W S + L G Y +++++
Sbjct: 16351 LAWKPPLQDGGSDIINYIVERRETSRLV-WTVVDANVQTLSCKVTKLLEGNEYTFRIMAV 16409
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVS-A 743
+YG E P+ S V + P + VT +T S +V W A
Sbjct: 16410 NKYGVGE-------------PLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPA 16456
Query: 744 SD---TVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKY-----IVNVYQISE 795
SD + G+ +E E + + + L+ Y N +SE
Sbjct: 16457 SDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSE 16516
Query: 796 DGEQSLILSTSQTTAPDAPPD-PTVDQVDDTSIVVRWSRP----QAPITGYRIVYSPSVE 850
S PP+ P V + +S+ + WS+P I GY +
Sbjct: 16517 PSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSV 16576
Query: 851 GSSTELNLPETAN--SVTLSDLQPGVQYNITIYAVE-----ENQESTPVVIQQETTGTPR 903
G T P N ++ + L +YN I A+ E+ + +I +E P
Sbjct: 16577 GEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPD 16636
Query: 904 SDTVPSPRDLQFVEVTDVK--------VTIMWTP-PE---SAVTGYRVDVIPVNLPGEHG 951
D DL+ ++ +++ V I P PE V G D +++
Sbjct: 16637 IDL-----DLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFT 16691
Query: 952 QRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDS 1011
+ + N + Y S G +S +T + P NL+ T
Sbjct: 16692 SLVLDNVNRYDSGK--------YTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKD 16743
Query: 1012 TVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLV 1067
+V + W PP ++I Y + R + + + LQ Y +
Sbjct: 16744 SVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVT 16803
Query: 1068 A-----IKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIG------FK 1116
A I ++ V QP I +VT ++ ++WT G +
Sbjct: 16804 AENEYGIGLPAQTADPIKVAEVPQPPGKITV--DDVTRNSVSLSWTKPEHDGGSKIIQYI 16861
Query: 1117 LGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERD-----APIVNK-- 1169
+ ++ + S V++ LT G EY++ + + + D PIV K
Sbjct: 16862 VEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDL 16921
Query: 1170 VVTPLSPP--TNLHLEANPDTGVL---------TVSWERSTTPDITGYRITTTPTNGQQG 1218
V+ P P ++ ++ D + T++W + P RI T +
Sbjct: 16922 VIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTT 16981
Query: 1219 NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNI 1278
S++E H D G +Y ++V V K + T+ PP ++F ++
Sbjct: 16982 LSIKET-HKDD----------GGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDV 17030
Query: 1279 GPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEE-DVAELSISPSDNAVVLTNLLPGTEY 1334
+++ ++W PP +TN++V+ DV +++ + + +T L GTEY
Sbjct: 17031 SAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVART--TLKVTKLKTGTEY 17088
Query: 1335 VVSV--SSVYEQH---ESTPLRGRQKTGLDSPTGIDFSD-ITANSFTVHWIAP----RAT 1384
+ + Y Q ES P+ + P G F+ I+ +S + W P +
Sbjct: 17089 QFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSP 17148
Query: 1385 ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQ 1444
+ GY + + + ++ NL G EY + A E+ + +G+
Sbjct: 17149 VIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYA-----ENIVGVGKA 17203
Query: 1445 STVSD--VPRDLEVVAATPTSLLISWDAPAVTVRYYRITY--GETGGNSPVQEFTVPGSK 1500
S S+ V RD TP +++ + +T+++ + Y G V++ +P +
Sbjct: 17204 SKNSECYVARDPCDPPGTPEPIMVKRNE--ITLQWTKPVYDGGSMITGYIVEKRDLPDGR 17261
Query: 1501 -----------STATISGLKPGVDYTITVYAVTGRGDSPASSKPIS----INYRTEIDKP 1545
+ T+SGL Y V A G A SKP I + E++ P
Sbjct: 17262 WMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAG---AISKPSDSTGPITAKDEVELP 17318
Query: 1546 SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPT 1605
+D + + +R+ P PT G + E +
Sbjct: 17319 RISMDPKFRDTIVV-------NAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKN 17371
Query: 1606 VEYVVSVY---------------AQNPSGESQPLVQTAVTNIDRPKG----LAFTDVDVD 1646
++ + A N +G V V +DRP + T V +
Sbjct: 17372 TDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKV--LDRPGPPEGPVQVTGVTSE 17429
Query: 1647 SIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSV 1702
+ W P +S Y V + A + ++ ++ L G+EY +
Sbjct: 17430 KCSLTWSPPLQDGGSDISHY-VVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRI 17488
Query: 1703 VALH-----DDMESQPLIGTQSTAIPAPT-DLKFTQVTPTSLSAQWTPPNV----QLTGY 1752
+A++ + +ES P++ +P P L+ T + S++ W P+ ++ GY
Sbjct: 17489 MAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGY 17548
Query: 1753 RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVV---- 1808
V + +K + V+GL +YE V A P+ V
Sbjct: 17549 IVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKA 17608
Query: 1809 -TTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKP 1863
+ PP A + D T+ +IT++W I G+ V+ A+ + + + P
Sbjct: 17609 CDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEE--WQIVTP 17666
Query: 1864 D----VRSYTITGLQPGTDYKIYLYTLN----DNARSSPVVIDASTAIDAPSNLRFLATT 1915
V + I+ L +YKI + LN A S P + ++AP L +
Sbjct: 17667 QTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAP-ELDLDSEL 17725
Query: 1916 PNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP---RPRPGVTEATITG-------LEP 1965
++V + G R +P RP P +T + G +E
Sbjct: 17726 RKGIVV-----------------RAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEK 17768
Query: 1966 GTEYT-------------IYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILD 2012
G YT Y++ L+N+ S+ K + P P NL E+
Sbjct: 17769 GVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPG----PPQNLAVKEVRK 17824
Query: 2013 VPSTVQKTPFVTHPGYDTGNGI----------------QLPGTSGQQPSVGQQMIF---- 2052
+ + P + G N + + TS + ++ + I+
Sbjct: 17825 DSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRV 17884
Query: 2053 -EEHGFRRTTPPTTATPIRHRPRPYPP-NVGQEALSQTTIS--W-APFQDTSE----YII 2103
E+ F P T ++ P PP V +SQT+ S W P D Y++
Sbjct: 17885 MAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVV 17944
Query: 2104 SCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSV 2163
P GT E +A +TGL+ G Y V+A ++ + R V+ V
Sbjct: 17945 EMQPKGT--EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPR--VLGVPVIA 18000
Query: 2164 NEGLNQPTDDSCFDPYTV 2181
+ QP+ F+ Y++
Sbjct: 18001 KDLTIQPSLKLPFNTYSI 18018
Score = 89.7 bits (221), Expect = 3e-17
Identities = 260/1286 (20%), Positives = 475/1286 (36%), Gaps = 231/1286 (17%)
Query: 780 LLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPIT 839
++P ++Y++ V ++ G + A D PT+D IV+ + P+
Sbjct: 8045 VVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVP 8104
Query: 840 GYRIVYSPSV----EGSSTELNLPETANSVTLS---DLQPGVQYNITIYAV--EENQEST 890
+R V P+V +G + + T + +S ++ V+ + IY + E S
Sbjct: 8105 -FRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSA 8163
Query: 891 PVVIQQETTGTPRSDTVPSP-RDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGE 949
I + G +P P +D++ ++T + W PPE G + V E
Sbjct: 8164 TASINVKVIG------LPGPCKDIKASDITKSSCKLTWEPPE--FDGGTPILHYVLERRE 8215
Query: 950 HGQR--LPI--SRNTFA-EVTGLSPGVTYYFKVFAVSH--GRE----SKPLTAQQTTKL- 997
G+R +P+ N + V L P Y+F+V AV+ G E P+ AQ +
Sbjct: 8216 AGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPP 8275
Query: 998 DAPTNLQFVNETDSTVLVRWTPPR----AQITGY---RLTVGLTRRGQPRQYNVGPSVSK 1050
D P +++ N T + + W PP ++I GY ++ G R + ++ V +
Sbjct: 8276 DPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLV--PILT 8333
Query: 1051 YPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
Y + L+ EY + A A G+ +P + PP T + A
Sbjct: 8334 YTAKGLEEGKEYQFRVRA-------ENAAGIS---EPSRATPP--------TKAVDPIDA 8375
Query: 1111 PRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVL--RDGQERDAPIVN 1168
P++ + + +G E + S SGS P + ++ V+ + ++R AP+V
Sbjct: 8376 PKVILRTSLEVKRGDEIALDA-SISGSPY-----PTITWIKDENVIVPEEIKKRAAPLVR 8429
Query: 1169 KVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHAD 1228
+ + L P T L++ N ++G S V
Sbjct: 8430 RRKGEVQEEEPFVL---PLTQRLSID-------------------NSKKGESQLRVR--- 8464
Query: 1229 QSSCTFDNLSPGLEYNVSVYTVKDDK--ESVPISDTIIPAVPPPTDLRFTNIGPDTMRVT 1286
D+L P ++ + + V++D P + +++ PP + F +I ++
Sbjct: 8465 ------DSLRP--DHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCK 8516
Query: 1287 WAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE 1346
W PP D + ++ Y+ K ++ P +V+T+ L +Y SV+ + E E
Sbjct: 8517 WEPPLD-DGGSEIINYTLEKKDKT------KPDSEWIVVTSTLRHCKY--SVTKLIEGKE 8567
Query: 1347 ------------------STPLRGRQKTGL-DSPTGIDFSDITANSFTVHWIAPR---AT 1384
S PL + G D+P D+T+NS V W P+ +
Sbjct: 8568 YLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSP 8627
Query: 1385 ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLL 1440
I GY + + + R ++ + + L G YV + A N G+ P
Sbjct: 8628 ILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPP-- 8685
Query: 1441 IGQQSTVSD--------VPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGN 1488
T D +PR V + T++ + W+ PA + Y + G N
Sbjct: 8686 -SDPKTAHDPISPPGPPIPR---VTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTN 8741
Query: 1489 SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEIDKPSQ 1547
+ T+ ++ G DY + V AV G+ P ++P+++ E +P
Sbjct: 8742 EWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQPVTV---AEPQEPPA 8798
Query: 1548 MQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTK--TKTAGP-DQTEMTIEGLQP 1604
+++ +SVK R+ P PTK TK G D+ + I+ +
Sbjct: 8799 VEL------DVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGT 8852
Query: 1605 TVEYVVS-----------VYAQNPSGESQPLVQTAVTNIDRP-KGLAFTDVDVDSIKIAW 1652
E ++ + A N G + V ++ P L + + W
Sbjct: 8853 KSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNW 8912
Query: 1653 ESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH-- 1706
P+ +++ + + + +H + E ++ GL G EY V+A +
Sbjct: 8913 SDPEDDGGSEITGFIIERKDAK--MHTWRQPIETERSKCDITGLLEGQEYKFRVIAKNKF 8970
Query: 1707 ---DDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTP 1758
+E P++ P +P L +T+ T ++++ W P + GY +
Sbjct: 8971 GCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRR 9030
Query: 1759 KEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPA--QGVVTTLENVSP 1816
+K + ++S +V L YE V A+ + S P+ VV + V P
Sbjct: 9031 HDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPP 9090
Query: 1817 PRRARVTDATETTIT-------------------ISWRTKTETITGFQVDAVPANGQTPI 1857
+ R++ +T I W +K ET+ DA+ +
Sbjct: 9091 TIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEW-SKNETVIEKPTDALQITKEEVS 9149
Query: 1858 QRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI-DAPSNLRFLATT- 1915
+ K ++ GT YT+ + R V + + D PS R LA T
Sbjct: 9150 RSEAKTELSIPKAVREDKGT------YTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTD 9203
Query: 1916 --PNSLLVSWQPP----RARITGYII 1935
S ++W P + IT Y+I
Sbjct: 9204 IKAESCYLTWDAPLDNGGSEITHYVI 9229
Score = 87.4 bits (215), Expect = 1e-16
Identities = 347/1579 (21%), Positives = 545/1579 (34%), Gaps = 257/1579 (16%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W +P+ S I+ Y++ R + W T + T++GL G Y ++ +
Sbjct: 10330 LTWFSPEDDGGSPITNYVIEKRESDRRA-WTPVTYTVTRQNATVQGLIQGKAYFFRIAAE 10388
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
G F TS + + T P P V E+T ++ ++W
Sbjct: 10389 NSIGMGP-----FVETSEALVIREPI----TVPERP---EDLEVKEVTKNTVTLTWNPPK 10436
Query: 745 DTVSGFRVEYELSEE--GDEPQYLDLPSTATS--VNIPDLLPGRKYIVNVYQISEDGEQS 800
+ Y L G E + S + L G Y V ++ G+
Sbjct: 10437 YDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGK 10496
Query: 801 LILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPE 860
T T D PT+ + +R A Y P V E ++ E
Sbjct: 10497 PSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 10556
Query: 861 TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET---TGTPRSDTVPSPRD----L 913
+ T P I A + VV++ T G + + V P +
Sbjct: 10557 --DDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPV 10614
Query: 914 QFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI---SRNTFAEVTG 966
F EVT + I W PP S +T Y ++ V +P+ S T +V+
Sbjct: 10615 SFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVG----KDVWMPVTSASAKTTCKVSK 10670
Query: 967 LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD------APTNLQFVNETDSTVLVRWTPP 1020
L G Y F++ A + S PL + D AP T + LV W P
Sbjct: 10671 LLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP 10730
Query: 1021 R---AQITGYRLTVGLTRRGQPRQYNVGP--SVSKYPLRNLQPASEYTVSLVA---IKGN 1072
IT Y L T + + P +K+ + +L +Y + A I
Sbjct: 10731 HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIG 10790
Query: 1073 QESPKATGVFTTLQPGSSIPPYNTEVTETT---IVITWTPAPR-------IGFKLGVRPS 1122
SP + VF PP N E +TT + +TW P PR +G+ + +
Sbjct: 10791 DPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQP-PRHDGGSKILGYIVEYQ-K 10848
Query: 1123 QGGEAPREVTSDSGSIV-----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP---L 1174
G E R S V+GL G Y + + + E D V + V L
Sbjct: 10849 VGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRL 10908
Query: 1175 SPPTNLHLEANP---------DTGVLT----------VSWERSTTPDITGYRITTTPTNG 1215
PP L L+AN DT L+ V+W++ T RI TP
Sbjct: 10909 EPP-ELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS 10967
Query: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRF 1275
+ + H D + +P VSV + DK PP DL
Sbjct: 10968 KL--EIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG------------PPRDLEV 11013
Query: 1276 TNIGPDTMRVTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332
+ I D+ +TW P +TN++V V + + + LS + + +L G
Sbjct: 11014 SEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ-WSPLSATSKKKSHFAKHLNEGN 11072
Query: 1333 EYVVSVSSVYEQHESTPLRGRQKT--GLDS------PTGIDFSDITANSFTVHWIAPR-- 1382
+Y+ V++ Q+ P K LD P + D+ ++ W P
Sbjct: 11073 QYLFRVAAE-NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRD 11131
Query: 1383 --ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREE 1436
+ ITGY + + E + V + +T L G Y + A N G +
Sbjct: 11132 GGSPITGYLVEYQEEGTQDWIKFKTVTNLE--CVVTGLQQGKTYRFRVKAENIVGLGLPD 11189
Query: 1437 SPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTV 1496
+ + I Q + VP +E+ L++ TVR+ I G P ++T
Sbjct: 11190 TTIPIECQEKL--VPPSVELDVKLIEGLVVK---AGTTVRFPAIIRGVP---VPTAKWTT 11241
Query: 1497 PGSK---------------STATISGL--KPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
GS+ S TI + +Y ITV + A SK ++++
Sbjct: 11242 DGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV-------SNAAGSKTVAVHL- 11293
Query: 1540 TEIDKPSQ----MQVTDVQDNSISVKWLP----SSSPVTGYRVTT--TPKNGPGPTKTKT 1589
T +D P + + DV +++ W P SPV Y V T K+ G +
Sbjct: 11294 TVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVV---S 11350
Query: 1590 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR------PKGLAFTDV 1643
+G +T++ I LQ EYV V A+N G PL T + P TD+
Sbjct: 11351 SGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDI 11410
Query: 1644 DVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQ----GLRPGSEYT 1699
++ ++W P+ Y + + + + A+L+ GL G+ Y
Sbjct: 11411 TENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVN-KTPIADLKFRVTGLYEGNTYE 11469
Query: 1700 VSVVALH------DDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPP----NVQ 1748
V A + S P+ + P P + K + + WT P
Sbjct: 11470 FRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSP 11529
Query: 1749 LTGYRVRVTPKEKTGPMKEINLAP--DSSSVVVSGLMVATKYEVSVYALKDTLTSRP--- 1803
+ GY V K T IN + V GL+ +Y + A P
Sbjct: 11530 ILGYVVE-CQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPREL 11588
Query: 1804 AQGVVTTLENVSPPR-------RARVTDATETTITISWRTK-------TETITG------ 1843
A+ V+ + + PP R +T TI I R K T T G
Sbjct: 11589 AESVIAK-DILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVRE 11647
Query: 1844 FQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI 1903
+VD + + +Q IK VR+ Y I + +A+ S +V +
Sbjct: 11648 KRVDLIQDLPRVELQ--IKEAVRA-------DHGKYIISAKNSSGHAQGSAIV----NVL 11694
Query: 1904 DAP---SNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVT 1956
D P NL+ T + +SW+ P + IT +I++Y KP +V VT
Sbjct: 11695 DRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIV---ASDVT 11751
Query: 1957 EATI-TGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPS 2015
+ I L EY V A +N P I K P L P PE L +
Sbjct: 11752 KRLIKANLLANNEYYFRVCA-ENKVGVGPTIETK----TPILAINPIDRPGEPENLHIAD 11806
Query: 2016 TVQKTPFV--THPGYDTGN 2032
+ ++ P YD G+
Sbjct: 11807 KGKTFVYLKWRRPDYDGGS 11825
Score = 85.5 bits (210), Expect = 6e-16
Identities = 330/1597 (20%), Positives = 570/1597 (35%), Gaps = 278/1597 (17%)
Query: 737 VVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQ 792
+++W D ++GF +E + ++ Q ++ + + +I LL G++Y V
Sbjct: 8909 LLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIE--TERSKCDITGLLEGQEYKFRVIA 8966
Query: 793 ISEDG-----EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQA----PITGYRI 843
++ G E IL+ P +P T + ++I + W P++ PI GY I
Sbjct: 8967 KNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYII 9026
Query: 844 VY----SPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTP-----VVI 894
P E + L P T S + +L Y + AV E ES P VVI
Sbjct: 9027 EKRRHDKPDFERVNKRL-CPTT--SFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVI 9083
Query: 895 QQETTG-------TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLP 947
Q + + R DT+ ++ E + + P VI
Sbjct: 9084 QDDEVPPTIKLRLSVRGDTIK----VKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTD 9139
Query: 948 GEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH----GRESKPLTAQQTTKLDAPTNL 1003
+ +SR+ + V + V+ G + + + + P NL
Sbjct: 9140 ALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNL 9199
Query: 1004 QFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV--SKYPLRNLQ 1057
+ + + W P ++IT Y + R + V + +Y + L
Sbjct: 9200 AVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLI 9259
Query: 1058 PASEYTVSLVAIKGNQESPKATGVFTTLQ-----PGSSIPPYNTEVTETTIVITWTP--- 1109
P +Y + A+ S + +Q PG P T+ +++++WTP
Sbjct: 9260 PNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLD 9319
Query: 1110 ---APRIGFKLGVRP------SQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVLR-- 1157
+P G+ L R S+ AP G V L GV+Y + +
Sbjct: 9320 NGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAA 9379
Query: 1158 ----DGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE---RSTTPDITGYRITT 1210
+ D + + P PP+ ++ + + ++ W+ + I GY +
Sbjct: 9380 GIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSI-SLGWKPPAKDGGSPIKGYIVEM 9438
Query: 1211 TP---TNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAV 1267
T+ ++ N ++++ + C NL +Y V V + ES P SDT
Sbjct: 9439 QEEGTTDWKRVNEPDKLITTCE--CVVPNLKELRKYRFRVKAVNEAGESEP-SDTT--GE 9493
Query: 1268 PPPTDLR-----FTNIGPDTMRVTWA-------------PPPS----IDLTNFLVRYSPV 1305
P TD++ F +IG V A P P D V
Sbjct: 9494 IPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGV 9553
Query: 1306 KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP-LRGRQKTGLDSPTGI 1364
+ + A+L + + + +++ S+++ + + T R + P +
Sbjct: 9554 HDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDL 9613
Query: 1365 DFSDITANSFTVHWIAPRAT----ITGYRIRHHPEHFSGRPREDRVPH-SRNSITLTNLT 1419
SDIT S + W P I GY I G+ P + + +L
Sbjct: 9614 KVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRT--IDGKAWTKVNPDCGSTTFVVPDLL 9671
Query: 1420 PGTEYVVSIVALNGREESPLLIGQQSTVS-------DVPRDLEVVAATPTSLLISWDAPA 1472
+Y + A N P + Q T + D P L++ T ++ +SW P
Sbjct: 9672 SEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPP- 9730
Query: 1473 VTVRYYRITYGETGGNSPVQEFTVP-------GSKSTA--------------TISGLKPG 1511
+ G SPV + V G+K A T+ L G
Sbjct: 9731 -----------KNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEG 9779
Query: 1512 VDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTG 1571
+Y V AV G S S+ P Q D+ SI +K T
Sbjct: 9780 GEYEFRVKAVNAAGVSKPSATV----------GPCDCQRPDMPP-SIDLKEFMEVEEGTN 9828
Query: 1572 YRVTTTPKNGPGPT----KTKTAGPDQTEMTIEGLQPTVEYV----VSVYAQNPSGESQP 1623
+ K P PT K PD E + V V Q+ ++
Sbjct: 9829 VNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGL 9888
Query: 1624 LVQTAVTNIDR---------------PKG-LAFTDVDVDSIKIAWESPQ----GQVSRYR 1663
TAV N+ P G + F V D + ++W P+ +++ Y
Sbjct: 9889 YTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYV 9948
Query: 1664 VTY--SSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVA-----LHDDMESQPLIG 1716
+ ++ + +H + + +E T + L G EY ++A + + ++S+P
Sbjct: 9949 IEKREANRKTWVHV---SSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETA 10005
Query: 1717 TQSTAIP-APTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPM-KEINL 1770
++P AP + VT S++ W P +TGY + + K+ T K +N
Sbjct: 10006 RNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEM--KDTTSKRWKRVNR 10063
Query: 1771 APDSS-----SVVVSGLMVATKYEVSVYALKD------TLTSRPAQGVVTTLENVSPPRR 1819
P + S V+GL+ + Y+ VYA+ +L S PA T + ++PP
Sbjct: 10064 DPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPA----TARDPIAPPGP 10119
Query: 1820 A--RVTDATETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRS--YTIT 1871
+VTD T+++ + W + +TG+ V+ G+ ++ +VR +T
Sbjct: 10120 PFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVE-YKEEGKEEWEKGKDKEVRGTKLVVT 10178
Query: 1872 GLQPGTDYKIYLYTLNDNARSSPV----VIDASTAIDAPSNLRFLATTPNSLLVSWQPPR 1927
GL+ G YK + +N P VI+ + +P +L+ A+ + ++V
Sbjct: 10179 GLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSP-DLQLDASVRDRIVVH-AGGV 10236
Query: 1928 ARITGYIIKYEKPGSPPREVV--PRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP- 1984
RI Y+ G PP V R EATI T + +KN Q+S
Sbjct: 10237 IRIIAYV-----SGKPPPTVTWNMNERTLPQEATIE-----TTAISSSMVIKNCQRSHQG 10286
Query: 1985 ---LIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQL----P 2037
L+ + + E + + + ++LDVP V TPF+ H T +L P
Sbjct: 10287 VYSLLAKNEAGERKKTIIV--------DVLDVPGPVG-TPFLAHNL--TNESCKLTWFSP 10335
Query: 2038 GTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQ----EALSQTTISWA 2093
G P + +I + RR P T T R G+ ++ +I
Sbjct: 10336 EDDGGSP-ITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMG 10394
Query: 2094 PFQDTSEYIISCHPVGTDEEPLQFRVPG-TSTSATLT 2129
PF +TSE ++ P+ E P V T + TLT
Sbjct: 10395 PFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLT 10431
Score = 85.5 bits (210), Expect = 6e-16
Identities = 343/1679 (20%), Positives = 586/1679 (34%), Gaps = 264/1679 (15%)
Query: 611 PVEVFITETPSQPNSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNS-Y 666
P V +T+T S ++W+ P I YI+ K +G W + + + Y
Sbjct: 21952 PTVVKVTDTSKTTVS--LEWSKPVFDGGMEIIGYIIEMC-KADLGDWHKVNAEACVKTRY 22008
Query: 667 TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
T+ L+ G Y+ ++ +I G + S T V T P + A +
Sbjct: 22009 TVTDLQAGEEYKFRVSAINGAGKGD---------SCEVTGTIKAVDRLTAPELDIDANFK 22059
Query: 727 SVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLP 782
+ A + + +++ + T + + LS D D ST T N
Sbjct: 22060 QTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADI-HTTDSFSTLTVENCNRNDA 22118
Query: 783 GRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----API 838
G KY + V S G +S+ + P P T V S + W P A I
Sbjct: 22119 G-KYTLTVENNS--GSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARI 22175
Query: 839 TGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898
Y + + S ++ T ++DL GV Y + AV E P + +
Sbjct: 22176 HHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPI 22235
Query: 899 TGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVN----LPGEH 950
T + PR L V+ + + W P+ S +TGY +++ + H
Sbjct: 22236 VATEQP---APPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGH 22292
Query: 951 GQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETD 1010
++L + E T Y F+V A + S+P A + + P
Sbjct: 22293 TKQLTFTVERLVEKT------EYEFRVKAKNDAGYSEPREAFSSVIIKEPQ--------- 22337
Query: 1011 STVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNV------GPSVSKYPLRNLQPASEYTV 1064
P A +TG + + G P +V P V+ + L ++ V
Sbjct: 22338 -------IEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVT-WKLEEMRLKETDRV 22389
Query: 1065 SLVAIKGN-----QESPKATG--VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIG--- 1114
S+ K ++S + F TL+ + + ++ T+V+ P P G
Sbjct: 22390 SITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSV-----TVVVIGRPGPVTGPIE 22444
Query: 1115 ----------FKLGVRPSQGGEAPREVTS------DSGS--------------IVVSGLT 1144
G P GG E+T+ +SG+ I V+ LT
Sbjct: 22445 VSSVSAESCVLSWG-EPKDGGGT--EITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLT 22501
Query: 1145 PGVEYVYTIQVL-RDGQER---DAPIV--NKVVTPLSP--PTNLHLEANPDTGVLTVSWE 1196
+EY + + R G + API+ + V P +P P H+ AN +++ WE
Sbjct: 22502 KYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSAN----AMSIRWE 22557
Query: 1197 RSTTPDITGYRITTTPTNGQQGNSL----EEVVHADQSSCTFDNLSPGLEYNVSVYTV-- 1250
G +I ++ N++ E V + + L GLEY Y +
Sbjct: 22558 EPYHDG--GSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNA 22615
Query: 1251 ----KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYS 1303
K + S PI V P T++ T+ + W+ P + +++
Sbjct: 22616 AGVSKASEASRPIMAQ--NPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERK 22673
Query: 1304 PVKNEEDVAELSIS---PSDNAVVLTNLLPGTEYVVSVSS------VYEQHEST-PLRGR 1353
PV D L + SDN +T L G Y V + + + EST P+ R
Sbjct: 22674 PVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCR 22733
Query: 1354 Q-----KTGLDSPTGIDFSDITANSFTVHWIA----PRATITGYRIRHHPEHFSGRPRED 1404
K LD+ D I A S V A P I + + +
Sbjct: 22734 DEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY 22793
Query: 1405 RVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRD---LEVVAATP 1461
+ I + + +Y +++ +G + +++ V D P L V T
Sbjct: 22794 TGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMV----KVLDSPGPCGKLTVSRVTQ 22849
Query: 1462 TSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT--ISGLKPGVDYT 1515
++W P + +Y + ET S + V G T + ++ L +Y
Sbjct: 22850 EKCTLAWSLPQEDGGAEITHYIVERRET---SRLNWVIVEGECPTLSYVVTRLIKNNEYI 22906
Query: 1516 ITVYAVTGRGDS-PASSKPISINYRTEIDKPSQM-QVTDVQDNSISVKWLPSSSP----V 1569
V AV G P S+PI I P + + I ++W S +
Sbjct: 22907 FRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEI 22966
Query: 1570 TGYRVTTTPKNGPGPTKT-KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628
+ Y V K T+ K T + + L +Y V A N +G S+P +
Sbjct: 22967 SNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASN 23026
Query: 1629 VTNIDRPK-------GLAFTDVDVDSIKIAWESPQGQVSRYRVTY-----SSPEDGIHEL 1676
+ P D SI +AW P V Y D + +
Sbjct: 23027 FISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRV 23086
Query: 1677 FPAPDGEEDTAELQGLRPGSEYTVSVVALH---------DDMESQPLIGTQSTAIPAPTD 1727
+ L+ G +Y+ V A++ E +P+ + + D
Sbjct: 23087 HTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADD 23146
Query: 1728 LKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTG---PMKEINLAPDSSSVVVSGLMV 1784
LK T S + V ++G V K G + I +S S+++ +
Sbjct: 23147 LKKTVTIRAGASLRLM---VSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKV- 23202
Query: 1785 ATKYEVSVYALKDTLTS--RPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT---- 1838
+Y+ Y ++ S + A +V + P +V + + ++TI+W T
Sbjct: 23203 -NRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGG 23261
Query: 1839 ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIY-----LYTLNDNARSS 1893
+ + V+ A + T K Y I+GL GT Y +Y + + +S
Sbjct: 23262 APVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETS 23321
Query: 1894 PVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVP 1949
V+ + + P+ L + T +++ ++W+ P +R+TGY+++ K G+ V
Sbjct: 23322 DAVLVSEVPL-VPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVV 23380
Query: 1950 RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPE 2009
+P V E T+T L G +Y + A SEP E VT+ +L
Sbjct: 23381 TLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEP-------RETVTAVTV--QDLRVLP 23431
Query: 2010 ILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPI 2069
+D+ + QKT V G ++L +P F R + T T
Sbjct: 23432 TIDLSTMPQKTIHV-----PAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHT 23486
Query: 2070 RHRPRPYPPNVGQEALSQTTISWAPFQDTSEYIISCHPV-GTDEEPLQFRV---PGTST 2124
+ V + + +TTI +DT EY + V GT E ++ + PG T
Sbjct: 23487 K---------VAKLTIRETTI-----RDTGEYTLELKNVTGTTSETIKVIILDKPGPPT 23531
Score = 84.3 bits (207), Expect = 1e-15
Identities = 258/1201 (21%), Positives = 430/1201 (35%), Gaps = 157/1201 (13%)
Query: 908 PSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS------RNTF 961
P L EVT K + W PP G ++D V RL + + T
Sbjct: 15252 PPEGPLAVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQK--RETSRLAWTNVASEVQVTK 15308
Query: 962 AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL------DAPTNLQFVNETDSTVLV 1015
+VT L G Y F+V AV+ +PL ++ + D P N + T +++V
Sbjct: 15309 LKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVV 15368
Query: 1016 RWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVS-----KYPLRNLQPASEYTVSLVAIK 1070
W P + + + RR + Q + + +Y + L EY ++A
Sbjct: 15369 CWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAEN 15428
Query: 1071 G-NQESPKATGVF-----TTLQPGSSIPPYNTEVTETT---IVITWTP------APRIGF 1115
+P T F T +PG PP N V +T+ I I W + G+
Sbjct: 15429 AAGISAPSPTSPFYKACDTVFKPG---PPGNPRVLDTSRSSISIAWNKPIYDGGSEITGY 15485
Query: 1116 KLGVRPSQGGEAPREVTSDSG----SIVVSGLTPGVEYVYTIQVLRD---GQERDAPIVN 1168
+ + + E + VT +G S ++GLT EY I + G+ P
Sbjct: 15486 MVEIALPEEDEW-QIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTP 15544
Query: 1169 KVVTPLSPPT-NLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
K + PP L + + R P I G G SL++
Sbjct: 15545 KAEDRMLPPEIELDADLRKVVTIRACCTLRLFVP-IKGRPAPEVKWARDHGESLDKASIE 15603
Query: 1228 DQSSCTFDNLSPGLEYNVSVY--TVKDDK--ESVPISDTIIPAVPPPTDLRFTNIGPDTM 1283
SS T + ++ Y TV++ +S ++ ++ PP DL+ + ++
Sbjct: 15604 STSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSV 15663
Query: 1284 RVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD---NAVVLTNLLPGTEYVVSVSS 1340
+TW PP +D + + Y K E S ++ + + L G Y V +
Sbjct: 15664 TLTW-DPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLA 15722
Query: 1341 VYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR----ATITGYRIRH 1392
E P + P I D+T NS ++ W P + I GY +
Sbjct: 15723 ENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEM 15782
Query: 1393 HPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPR 1452
+ V + T+T L G EY + A N E + +Q +V + +
Sbjct: 15783 QTKGSDKWATCATVKVTE--ATITGLIQGEEYSFRVSAQN---EKGISDPRQLSVPVIAK 15837
Query: 1453 DLEVVAA------TPTSLL---ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
DL + A T T L + D P + +T+ + N P+++ T ++ST
Sbjct: 15838 DLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKD--NVPLKQTTRVNAESTE 15895
Query: 1504 TISGL--KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ----MQVTDVQDNS 1557
S L K + Y V + + + +++ +DKP +++ +V +S
Sbjct: 15896 NNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNV---IVLDKPGPPTGPVKMDEVTADS 15952
Query: 1558 ISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG--LQPTVEYVVS 1611
I++ W P S + Y V K T + TI+ L+ EY
Sbjct: 15953 ITLSWGPPKYDGGSSINNYIVE---KRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFR 16009
Query: 1612 VYAQNPSGES-----QPLVQTAVTNIDRPKGLAFTDVDV-DSIKIAWESPQGQVSRYRVT 1665
+ A+N G+S +P V + P G + DS+++ W P +
Sbjct: 16010 IAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIG 16069
Query: 1666 YSSPEDGIHELF-------PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ 1718
Y + + P P + T GL G EY V A + +P ++
Sbjct: 16070 YHLERKERNSILWVKLNKTPIPQTKFKTT---GLEEGVEYEFRVSAENIVGIGKPSKVSE 16126
Query: 1719 STAIPAPTDL----KFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINL 1770
P D + VT S++ QW P ++TGY V + MK
Sbjct: 16127 CYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFT 16186
Query: 1771 APDSSSVVVSGLMVATKYEVSVYALKDT-LTSRPAQ--GVVTTLENVSPPRRARVTDATE 1827
+ V+GL+ +YE V A + S P++ G +T + V PPR + +
Sbjct: 16187 NIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKD 16246
Query: 1828 TTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ-PGTDYKIYLYTL 1886
T + + + F+VDA P + IK D L+ TD+ L ++
Sbjct: 16247 TIVVHAGES-------FKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSL-SV 16298
Query: 1887 NDNAR--SSPVVIDASTAIDAPS---NLRFL-------------ATTPNSLLVSWQPPR- 1927
D R S ++ A S N++ L T ++W+PP
Sbjct: 16299 KDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQ 16358
Query: 1928 ---ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
+ I YI++ + VV +T L G EYT ++A+ EP
Sbjct: 16359 DGGSDIINYIVERRETSRLVWTVVDA-NVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEP 16417
Query: 1985 L 1985
L
Sbjct: 16418 L 16418
Score = 83.6 bits (205), Expect = 2e-15
Identities = 268/1312 (20%), Positives = 473/1312 (36%), Gaps = 176/1312 (13%)
Query: 812 DAPPDPT----VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN 863
D P PT + + + S+ ++W P+ + +T Y ++ + TE++
Sbjct: 20263 DRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVART 20322
Query: 864 SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV-EVTDVK 922
+ + L G +Y I A EN+ I T P P +V VT
Sbjct: 20323 MMKVMKLTTGEEYQFRIKA--ENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRES 20380
Query: 923 VTIMWTPPES----AVTGYRVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
+T+ W P S AV GY +++ N + + +L I R T +VT +S G+ Y F+V
Sbjct: 20381 ITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVI-RTTHFKVTTISAGLIYEFRV 20439
Query: 978 FAVSHGRESKPL-TAQQTTKLDA---PTNLQFVNETDSTVLVRWTPPR----AQITGYRL 1029
+A + KP ++ +DA P N++ + + ++V + W P ++ITGY
Sbjct: 20440 YAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYI- 20498
Query: 1030 TVGLTRRGQP-----RQYNVGPSVSKYPLRNLQPASEYTVSLVA--IKGNQESP-KATGV 1081
+ RR P + + +++ + L S+Y + A G+ +P + G
Sbjct: 20499 ---VERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGP 20555
Query: 1082 FTTLQ----PGSSIPPYNTEVTE----TTIV----ITWTPAPRI-GFKLGVRPSQGGEAP 1128
T + P +P TEV + T++ I+ PAP I +K
Sbjct: 20556 ITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVC 20615
Query: 1129 REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
E T+D SI++ Y +++ A I +++ PP
Sbjct: 20616 VENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTA 20675
Query: 1189 GVLTVSWERSTTPD----ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
+T+ W R D IT Y + T+ + + E H ++ T + G EY
Sbjct: 20676 EKITLLW-RPPADDGGAKITHYIVEKRETSRVVWSMVSE--HLEECIITTTKIIKGNEYI 20732
Query: 1245 VSVYTVKDDKESVPI-SDTIIP-----AVPPPTDLRFTNIGPDTMRVTWAPP---PSIDL 1295
V V P+ SD+++ PP T I ++M V W+ P D+
Sbjct: 20733 FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDI 20792
Query: 1296 TNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY---VVSVSSVYEQHESTPLRG 1352
+ + + K+ L + D +T L ++Y V +V++ + S P
Sbjct: 20793 SGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEF 20852
Query: 1353 RQKTGLDSPTG----IDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPRED 1404
+ P G I +D T +S T+ W P + +TGY + E G E
Sbjct: 20853 YKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVV----EIRQGEEEEW 20908
Query: 1405 RVPHSRNSITLT-----NLTPGTEYVVSIVALN-GREESPLLIGQQSTVSDVPR----DL 1454
++ + T NL PG Y + A+N + P+ + + D+ DL
Sbjct: 20909 TTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDL 20968
Query: 1455 EVVAATPTSLLISWDA-----------PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
+V T D P VT R G S S S
Sbjct: 20969 DVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYS----IENTDSSSLL 21024
Query: 1504 TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISV 1560
TI + + G G+ +S+ + + +D P+ ++QV V ++++
Sbjct: 21025 TIPQVTRNDTGKYILTIENGVGEPKSSTVSVKV-----LDTPAACQKLQVKHVSRGTVTL 21079
Query: 1561 KWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGP-DQTEMTIEGLQPTVEYVVSVYAQ 1615
W P SP+ Y + ++ T + + T + L + V A+
Sbjct: 21080 LWDPPLIDGGSPIINYVI--EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAE 21137
Query: 1616 NPSGESQPLVQT---AVTNIDRP-KGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPED 1671
N G +P T + P + L+ D S+ ++W P Y
Sbjct: 21138 NEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERK 21197
Query: 1672 GIHELFPAPDGEEDTAELQ--GLRPGSEYTVSVVALHDDMESQPL-IGTQSTAIPAPTDL 1728
G E + G T E++ L+ S V A ++ S P+ IG P +
Sbjct: 21198 GKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIG--------PITV 21249
Query: 1729 KFTQVTP-TSLSAQWTPPNVQLT---GYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMV 1784
K +TP LS P Q+T G+ V + K P I+ D + S +
Sbjct: 21250 KELIITPEVDLS---DIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVR 21306
Query: 1785 ATKYEVSV-YALKDTLTSRPAQ------------GVVTTLENVSPPRR----ARVTDATE 1827
+K E + ++K+ + V T+ + PP + R +
Sbjct: 21307 FSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKA 21366
Query: 1828 TTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVR-SYTITGLQPGTDYKIY 1882
++ +SW + IT + ++ QT + R ++ + L +Y+
Sbjct: 21367 DSVILSWDVPEDNGGGEITCYSIEK-RETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFR 21425
Query: 1883 LYTLNDNARSSPVVIDASTA------IDAPSNLRFLATTPNSLLVSWQPP----RARITG 1932
+ N S P+V A P T + + ++W P + +TG
Sbjct: 21426 VRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTG 21485
Query: 1933 YIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
+ ++ ++ S + V E TGL G +Y V A + S P
Sbjct: 21486 FHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSP 21537
Score = 83.2 bits (204), Expect = 3e-15
Identities = 293/1378 (21%), Positives = 491/1378 (35%), Gaps = 236/1378 (17%)
Query: 811 PDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVT 866
P P + V + S + W P + IT Y I + S + E N+
Sbjct: 9193 PSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVI---DKRDASRKKAEWEEVTNTAV 9249
Query: 867 -----LSDLQPGVQYNITI-----YAVEENQESTPVVIQQ--ETTGTPRSDTVPSPRDLQ 914
+ L P QY + Y + + +S VVIQ G P V
Sbjct: 9250 EKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKV------- 9302
Query: 915 FVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLP-GEHGQRLPISR----NTFAEVT 965
+ T + + WTPP S +TGY ++ P R PI++ V
Sbjct: 9303 -LARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVP 9361
Query: 966 GLSPGVTYYFKVFAVSH---GRESKP----LTAQQTTKLDAPTNLQFVNETDSTVLVRWT 1018
L GV Y F+ A++ G S+P + P+ + ++T S++ + W
Sbjct: 9362 RLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWK 9421
Query: 1019 PPR----AQITGYRLTV---GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIK- 1070
PP + I GY + + G T + + + + + + NL+ +Y + A+
Sbjct: 9422 PPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVNE 9481
Query: 1071 -GNQESPKATG------------VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKL 1117
G E TG VF + + VI P P+ ++
Sbjct: 9482 AGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEF 9541
Query: 1118 GVRPSQG---------GEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVN 1168
+ + +A E +S I++ Y+I ++ A
Sbjct: 9542 DGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRV 9601
Query: 1169 KVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD------ITGYRITTTPTNGQQGNSLE 1222
KV+ PP +L + ++ G +SW+ PD I GY I +G+
Sbjct: 9602 KVMDVPGPPKDLKV-SDITRGSCRLSWKM---PDDDGGDRIKGYVIEKRTIDGKAWTK-- 9655
Query: 1223 EVVHADQSSCTF--DNLSPGLEYNVSV-----YTVKDDKESVPISDTIIPAVPP--PTDL 1273
V+ D S TF +L +Y V + + E++ + P PP P L
Sbjct: 9656 --VNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKL 9713
Query: 1274 RFTNIGPDTMRVTWAPPPS---IDLTNFLVR---YSPVK---------NEEDVAELSISP 1318
+ I +T+ ++W PP + +T+++V + P N+ DV EL +
Sbjct: 9714 KIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTV 9773
Query: 1319 SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL---DSPTGIDFSDI--TANS 1373
D L+ G EY V +V S P D P ID +
Sbjct: 9774 ED-------LVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEG 9826
Query: 1374 FTVHWIA-----PRATITGYRIRH----------HPEHFSGRPREDR----VPHSRNSIT 1414
V+ +A P T+T ++ + H + +D +P SR S T
Sbjct: 9827 TNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDT 9886
Query: 1415 LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP--- 1471
Y ++ V G + + ++ + + + +SW P
Sbjct: 9887 GL-------YTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDD 9939
Query: 1472 -AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG-DSPA 1529
+ Y I E + V + P + T TI L G +Y + A G P
Sbjct: 9940 GGSKITNYVIEKREANRKTWVHVSSEP-KECTYTIPKLLEGHEYVFRIMAQNKYGIGEPL 9998
Query: 1530 SSKPISI-NYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVT---TTPKN- 1580
S+P + N + P + V+ V NS++V W SPVTGY + TT K
Sbjct: 9999 DSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRW 10058
Query: 1581 ---GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG---ESQPLVQTAVTNIDR 1634
P K T G + GL +Y VYA N +G S P +
Sbjct: 10059 KRVNRDPIKAMTLG---VSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIA 10115
Query: 1635 PKGLAF---TDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTA 1687
P G F TD S + W P +V+ Y V Y E+G E D E
Sbjct: 10116 PPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYK--EEGKEEWEKGKDKEVRGT 10173
Query: 1688 EL--QGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPT-SLSAQWTP 1744
+L GL+ G+ Y V A++ +P G + I ++K V+P L A
Sbjct: 10174 KLVVTGLKEGAFYKFRVRAVNIAGIGEP--GEVTDVI----EMKDRLVSPDLQLDASVRD 10227
Query: 1745 PNVQLTGYRVRVT-------PKEKTGPMKEINLAPDSS--SVVVSGLMVATKYEVS---V 1792
V G +R+ P T M E L +++ + +S MV + S V
Sbjct: 10228 RIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGV 10287
Query: 1793 YAL--KDTLTSRPAQGVVTTLENVSPPRRARVT-DATETTITISWRTKTET----ITGFQ 1845
Y+L K+ R +V L+ P + + T + ++W + + IT +
Sbjct: 10288 YSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYV 10347
Query: 1846 VDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND-------NARSSPVV 1896
++ ++ + TP+ T+ ++ T+ GL G Y + N + V+
Sbjct: 10348 IEKRESDRRAWTPVTYTVTR--QNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVI 10405
Query: 1897 IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPR 1952
+ T + P +L T N++ ++W PP+ + I Y+++ G+ V
Sbjct: 10406 REPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDN 10465
Query: 1953 PGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVT----LPHPNLH 2006
+ T+ GL+ G Y V A+ ++G+ K + +T L P LH
Sbjct: 10466 LLSRKYTVKGLKEGDTYEYRVSAVN-------IVGQGKPSFCTKPITCKDELAPPTLH 10516
Score = 82.0 bits (201), Expect = 6e-15
Identities = 266/1310 (20%), Positives = 442/1310 (33%), Gaps = 219/1310 (16%)
Query: 731 ITASSFVVSWVSASDTVSGFRVEYELSE-EGDEPQYLDLPSTAT--SVNIPDLLPGRKYI 787
++A +SW D Y + + E + ++ + S + IP LL G +Y+
Sbjct: 9924 VSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYV 9983
Query: 788 V-----NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----API 838
N Y I E + + + + P AP PTV V S+ V W P+ +P+
Sbjct: 9984 FRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPV 10043
Query: 839 TGYRIVYSPSVEGSSTELNLPETANSVTL------SDLQPGVQYNITIYAVEENQESTPV 892
TGY + + +N + ++TL + L G Y +YA+ P
Sbjct: 10044 TGYWLEMKDTTSKRWKRVN-RDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVG-PA 10101
Query: 893 VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
+ + P P + + T + W+PP S VTGY V+
Sbjct: 10102 SLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEE 10161
Query: 949 EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGR-----------ESKPLTAQQTTKL 997
+ R T VTGL G Y F+V AV+ E K +L
Sbjct: 10162 WEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQL 10221
Query: 998 DAPTNLQFVNETDSTV----LVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSV--SKY 1051
DA + V + V PP +T + R P++ + + S
Sbjct: 10222 DASVRDRIVVHAGGVIRIIAYVSGKPPPT------VTWNMNERTLPQEATIETTAISSSM 10275
Query: 1052 PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT-EVTETTIVITWTP- 1109
++N Q + + SL+A E K V PG P+ +T + +TW
Sbjct: 10276 VIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSP 10335
Query: 1110 -----APRIGFKLGVRPS-QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD----- 1158
+P + + R S + P T + V GL G Y + I
Sbjct: 10336 EDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGP 10395
Query: 1159 -GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTN 1214
+ +A ++ + +T P +L ++ +T++W + +I Y + +
Sbjct: 10396 FVETSEALVIREPITVPERPEDLEVK-EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIG 10454
Query: 1215 GQQGNSLEEVVHADQSSCTFDNLSPG--LEYNVSVYTV----KDDKESVPISDTIIPAVP 1268
++ + + + T L G EY VS + K + PI T +
Sbjct: 10455 TEKFHKVTN-DNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPI--TCKDELA 10511
Query: 1269 PPT---------DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSI 1316
PPT +R T R + P P + S K+E DV E I
Sbjct: 10512 PPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKV---------SWFKDEADVLEDDRTHI 10562
Query: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP----TGIDFSDITAN 1372
+ + L + V E + Q +D P + F ++T +
Sbjct: 10563 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKD 10622
Query: 1373 SFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP----HSRNSITLTNLTPGTEYVVSI 1428
+ W P G +I ++ ++ +P ++ + ++ L G +Y+ I
Sbjct: 10623 YMVISW-KPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRI 10681
Query: 1429 VALNGREESPLLIG------QQSTVSDVPRDLEVVAATPTSLLISWDAP----------- 1471
A N S L+ + V D P V T S L++W+ P
Sbjct: 10682 HAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYI 10741
Query: 1472 -----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT--GR 1524
++ R+ R+T P +F VP L G Y V A G
Sbjct: 10742 LEKRETMSKRWARVTKDPI---HPYTKFRVP---------DLLEGCQYEFRVSAENEIGI 10789
Query: 1525 GDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRVTTT 1577
GD SKP+ + I KPS + D NS+ + W P S + GY +
Sbjct: 10790 GDPSPPSKPVFA--KDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGY-IVEY 10846
Query: 1578 PKNGPGPTKTKTAGPD---QTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LVQT 1627
K G + P+ +T+ + GL+ Y V A N +GES P LV+
Sbjct: 10847 QKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKD 10906
Query: 1628 AV--------TNIDRPKGLAFTDV--------DVDSIKIAWESPQGQVSRYRVTYSSPED 1671
+ N+ R + + D V K+ W+ +P
Sbjct: 10907 RLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVG 10966
Query: 1672 GIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFT 1731
E+ A + L P TVSV L D P DL+ +
Sbjct: 10967 SKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG------------PPRDLEVS 11014
Query: 1732 QVTPTSLSAQWTPP----NVQLTGYRVR-------------VTPKEKTGPMKEINLAPDS 1774
++ S W P +T Y V T K+K+ K +N
Sbjct: 11015 EIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLN----E 11070
Query: 1775 SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISW 1834
+ + + +Y + T +P + + L PP+ D +T +++ W
Sbjct: 11071 GNQYLFRVAAENQYGRGPF----VETPKPIK-ALDPLHPPGPPKDLHHVDVDKTEVSLVW 11125
Query: 1835 ----RTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYK 1880
R ITG+ V+ Q I+ ++ +TGLQ G Y+
Sbjct: 11126 NKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLEC-VVTGLQQGKTYR 11174
Score = 80.9 bits (198), Expect = 1e-14
Identities = 248/1194 (20%), Positives = 435/1194 (36%), Gaps = 142/1194 (11%)
Query: 908 PSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE 963
P +Q VT K ++ W+PP S ++ Y V+ + + N+ +
Sbjct: 17416 PPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSL-K 17474
Query: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA------PTNLQFVNETDSTVLVRW 1017
VT L G Y F++ AV+ +PL + + P +L+ N ++ V W
Sbjct: 17475 VTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCW 17534
Query: 1018 TPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQ---------PASEYTVSLVA 1068
P + G +G + R +K + +L+ E+ VS
Sbjct: 17535 NRPDSD--GGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAEN 17592
Query: 1069 IKGNQESPKATGVFTTLQPGSSI-PPYNTEVTETT---IVITWTP------APRIGFKLG 1118
G E AT + P PP N + +TT I + W + +G+ +
Sbjct: 17593 AAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVE 17652
Query: 1119 VRPSQGGEAPREVTSDSGSIV----VSGLTPGVEYVYTIQVLRD---GQERDAPIVNKVV 1171
+ + E + VT +G V +S LT EY + L G+ P K
Sbjct: 17653 ICKADEEEW-QIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPE 17711
Query: 1172 TPLSPPTNLHLEANPDTGVLT---------VSWERSTTPDITGYRITTTPTNGQQGNSLE 1222
L P L L++ G++ + ++ TP+IT R T+ Q +E
Sbjct: 17712 DKLEAP-ELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQ---IE 17767
Query: 1223 EVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDT 1282
+ V+ Q S + + +Y + + K + ++ ++ PP +L + D+
Sbjct: 17768 KGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAF-VTVKVLDTPGPPQNLAVKEVRKDS 17826
Query: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEED---VAELSISPSDNAVVLTNLLPGTEYVVSVS 1339
+ W PP ID + Y K E A +S S + + NL G Y V
Sbjct: 17827 AFLVWEPP-IIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVM 17885
Query: 1340 SVYEQHESTPLR---GRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIR 1391
+ E P+ + SP G + +D++ S ++ W P + + GY +
Sbjct: 17886 AENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE 17945
Query: 1392 HHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSIVALNGREES-PLLIGQQSTVSD 1449
P+ G + V S+ + +T L+ G EY + A N + +S P ++G D
Sbjct: 17946 MQPK---GTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKD 18002
Query: 1450 VPRDLEVVAATPTSLL-----ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT 1504
+ + T + + + P + I++ + G P+++ T + TAT
Sbjct: 18003 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDG--EPLKQTTRVNVEETAT 18060
Query: 1505 --ISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVK 1561
+ +K G Y VT + +++ +S+ + P ++ +V + + +
Sbjct: 18061 STVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVIS 18120
Query: 1562 WLPSS----SPVTGYRV-----TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV 1612
W P + ++ Y V TTT + T +T + I L+ EY +
Sbjct: 18121 WEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTT------IKITKLKTGTEYQFRI 18174
Query: 1613 YAQNPSGESQPLVQTAVT-----NIDRPKGLAF-TDVDVDSIKIAWESPQGQVSRYRVTY 1666
+A+N G+S PL AV P G F T + D + + W P + Y
Sbjct: 18175 FAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGY 18234
Query: 1667 SSPEDGIHELF-------PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQS 1719
+ + + P D + T GL G EY V A + +P ++
Sbjct: 18235 HLEQKEKNSILWVKLNKTPIQDTKFKTT---GLDEGLEYEFKVSAENIVGIGKPSKVSEC 18291
Query: 1720 TAIPAPTD----LKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLA 1771
P D + +T +++ +W P ++TGY V MK
Sbjct: 18292 FVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTN 18351
Query: 1772 PDSSSVVVSGLMVATKYEVSVYALKDTLT-SRP--AQGVVTTLENVSPPRRAR------- 1821
+ VSGL+ +YE V A S P + G +T + + P +
Sbjct: 18352 VLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDV 18411
Query: 1822 -VTDATET-TITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ-PGTD 1878
V A ET + R K + D +T + IK ++ T+ TD
Sbjct: 18412 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELE-ETAARMEIKSTIQKTTLVVKDCIRTD 18470
Query: 1879 YKIYLYTLND--NARSSPVVIDASTAIDAPSN-LRFLATTPNSLLVSWQPP----RARIT 1931
Y+ L++ +S P+ + P L+ T ++W PP A I+
Sbjct: 18471 GGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANIS 18530
Query: 1932 GYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 1985
YII+ + V + +T L PG EY V+A+ EPL
Sbjct: 18531 HYIIEKRETSRLSWTQVSTEVQAL-NYKVTKLLPGNEYIFRVMAVNKYGIGEPL 18583
Score = 78.6 bits (192), Expect = 7e-14
Identities = 278/1375 (20%), Positives = 475/1375 (34%), Gaps = 200/1375 (14%)
Query: 797 GEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGS 852
G +++ + P P D V ++ S + W P + IT Y +
Sbjct: 10991 GSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ 11050
Query: 853 STELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRD 912
+ L+ S L G QY + A + V + P+D
Sbjct: 11051 WSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKD 11110
Query: 913 LQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE----V 964
L V+V +V+++W P+ S +TGY V+ E G + I T V
Sbjct: 11111 LHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEY------QEEGTQDWIKFKTVTNLECVV 11164
Query: 965 TGLSPGVTYYFKVFA---VSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
TGL G TY F+V A V G + + KL P+ V + V+ T R
Sbjct: 11165 TGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVR 11224
Query: 1022 --AQITGYRL-TVGLTRRGQPRQYNVGPSV------SKYPLRNL--QPASEYTVSLVAIK 1070
A I G + T T G + + +V S ++N + EY +++
Sbjct: 11225 FPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV---- 11280
Query: 1071 GNQESPKATGVFTTLQ--PGSSIPPYNT-EVTETTIVITWTPAPRIGFKLGVRPSQGGEA 1127
N K V T+ PG P N +VT + I+W P P G +
Sbjct: 11281 SNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQP-----------PKDDGGS 11329
Query: 1128 P--------REVTSDSGSIVVSG----------LTPGVEYVYTIQV---LRDGQERDA-P 1165
P ++ D+ +V SG L G EYV+ ++ + G D+ P
Sbjct: 11330 PVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTP 11389
Query: 1166 IVNK-VVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSL 1221
V K +P SPP + + TVSW + ITGY + G+
Sbjct: 11390 TVAKHKFSPPSPPGK-PVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVN 11448
Query: 1222 EEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVP-----PPTDLRFT 1276
+ + + T E+ V + + P SD I P PP + +
Sbjct: 11449 KTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLK 11508
Query: 1277 NIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDN-----AVVLTNLLPG 1331
+ +T + W P S D + ++ Y + A+ + D A + L+ G
Sbjct: 11509 DKSRETADLVWTKPLS-DGGSPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEG 11567
Query: 1332 TEYVVSVSSVYEQHESTPLRGRQKT---GLDSPTGIDFSDITANSFTVHWIAPRATITGY 1388
EY + + E P + + P ++ D+T + I
Sbjct: 11568 NEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVEL-DVTCRDVITVRVGQTIRILA- 11625
Query: 1389 RIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE-------------YVVSIVALNGRE 1435
R++ PE +E +V + L P E Y++S +G
Sbjct: 11626 RVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHA 11685
Query: 1436 ESPLLIGQQSTVSDVP---RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQ 1492
+ ++ V D P ++L+V T + ISW+ P + G + + +
Sbjct: 11686 QGSAIVN----VLDRPGPCQNLKVTNVTKENCTISWENP--------LDNGGSEITNFIV 11733
Query: 1493 EFTVPGSKSTATISG----------LKPGVDYTITVYAVTGRGDSPASSKPISINYRTEI 1542
E+ P K + ++ L +Y V A G P I I
Sbjct: 11734 EYRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPI 11793
Query: 1543 DKPSQ---MQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 1595
D+P + + + D + +KW SP Y V K + +T
Sbjct: 11794 DRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKET 11853
Query: 1596 EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSI------- 1648
++ Y V +N GES V+T + D+ + +
Sbjct: 11854 HYMVDRCVENQIYEFRVQTKNEGGESD-WVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGD 11912
Query: 1649 KIAWESPQGQVSRYRVTYSSPEDGIHELFPAP----DGEEDTAELQGLRP----GSEYTV 1700
I E+ V ++ +D +L +P D D+++ + G +Y V
Sbjct: 11913 TIRLEAGVRGKPFPEVAWTKDKDAT-DLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVV 11971
Query: 1701 SVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKE 1760
+ + + P +LK V+ + W PP G ++ E
Sbjct: 11972 TATNTAGSFVAYATVNVLDKPGPV-RNLKIVDVSSDRCTVCWDPPEDD-GGCEIQNYILE 12029
Query: 1761 KTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV------ 1814
K K + + S++V+ G V E + Y + ++ G T + V
Sbjct: 12030 KC-ETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKY 12088
Query: 1815 ---SPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQ--TPIQRTIKPDV 1865
P VT ++ +T+ W ++ITG+ ++ + P+ ++ P+
Sbjct: 12089 DKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPE- 12147
Query: 1866 RSYTITGLQPGTDYKIYLYTLND------NARSSPVVI-DASTAIDAPSNLRFLATTPNS 1918
R + L P +Y+ + N+ + S PVV D P+N R + TT +S
Sbjct: 12148 RRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHS 12207
Query: 1919 LLVSWQPP----RARITGYIIKYEK--PGSPPREVVPRPRPGV----TEATITGLEPGTE 1968
+ + W P A I GY+++ + P E R E T+T L+ E
Sbjct: 12208 ITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQE 12267
Query: 1969 YTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFV 2023
Y V A NQ +G + EL + + P L PEI D+ ++++K V
Sbjct: 12268 YEFRVCA--QNQ-----VGIGRPAELKEAIK-PKEILEPPEI-DLDASMRKLVIV 12313
Score = 78.6 bits (192), Expect = 7e-14
Identities = 169/767 (22%), Positives = 275/767 (35%), Gaps = 120/767 (15%)
Query: 601 PLQTYPSSSGPVEVFITETPSQPN-------SHPIQWNAPQ---PSHISKYILRWRPKNS 650
P +T P VF+ PS+P + I W P + I+ Y + ++ +
Sbjct: 19763 PSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDD 19822
Query: 651 VGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT 710
WK + YTI GL G Y ++ S+ + G + + +S P +
Sbjct: 19823 TD-WKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASD-------PSDSSDPQIAKE 19874
Query: 711 VTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVS--GFRVEYELSEEGDEP----Q 764
E PL +E+ + V + S + TV G V L + D
Sbjct: 19875 REEE-----PLFDID---SEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA 19926
Query: 765 YLDLPSTATSVNIPDLL--PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV 822
Y+D + TS+ I + KY + + + +L++ T P P + TV V
Sbjct: 19927 YVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGP--PTNITVQDV 19984
Query: 823 DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNI 878
S V+ W P+ AP+ Y I + + + + S +++LQ G Y
Sbjct: 19985 TKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYF 20044
Query: 879 TIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAV 934
+ E P ++ G ++ P L ++ V++ W PE S +
Sbjct: 20045 RVSGENEFGVGIPAETKE---GVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRI 20101
Query: 935 TGYRVDVIPVNLPGEHGQR----LPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-- 988
Y V+ + E GQ+ ++++T V+GL Y+F+VFA + S P
Sbjct: 20102 VHYVVEAL------EKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRE 20155
Query: 989 -LTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
L + P + N TV VR G L V + G+P V S
Sbjct: 20156 LLLPVLIKEQLEPPEIDMKNFPSHTVYVR--------AGSNLKVDIPISGKPLP-KVTLS 20206
Query: 1048 VSKYPLR-NLQPASEYTV---------SLVAIKGNQESPKATGVFTTL---------QPG 1088
PL+ ++ +E T S+ A G E A TT +PG
Sbjct: 20207 RDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPG 20266
Query: 1089 SSI-PPYNTEVTETTIVITWTPAPRIG-------FKLGVRPSQGGEAPREVTSDSGSIVV 1140
P +++TE ++ + W P G L S T + V
Sbjct: 20267 PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKV 20326
Query: 1141 SGLTPGVEYVYTIQV-----LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
LT G EY + I+ + D + V T PP+ + N +TV W
Sbjct: 20327 MKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWV-TNVTRESITVGW 20385
Query: 1196 ERSTT---PDITGYRITTTPTNG---QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249
+ + GY + N Q+ N L V+ T +S GL Y VY
Sbjct: 20386 HEPVSNGGSAVVGYHLEMKDRNSILWQKANKL--VIRTTHFKVT--TISAGLIYEFRVYA 20441
Query: 1250 V------KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP 1290
K S P+ I A PP ++R T+I +++ ++W P
Sbjct: 20442 ENAAGVGKPSHPSEPV--LAIDACEPPRNVRITDISKNSVSLSWQQP 20486
Score = 66.2 bits (160), Expect = 4e-10
Identities = 301/1561 (19%), Positives = 557/1561 (35%), Gaps = 218/1561 (13%)
Query: 628 IQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W+AP S ++ + + + +NS+ K T P Y GL G+ Y+ ++ +
Sbjct: 21470 LTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAE 21529
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
G S+P + T +P P + ++T + + W
Sbjct: 21530 NSAG-------------LSSPSDPSKFTLAVSPVDP--PGTPDYIDVTRETITLKWNPPL 21574
Query: 745 DTVSGFRVEYELSEEGDEPQYLDLPSTATS---VNIPDLLPGRKYIVNVYQ------ISE 795
V Y + + +++ T S + L PG +Y + IS
Sbjct: 21575 RDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISP 21634
Query: 796 DGEQSLILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWS--RPQAPITGYRIV----YS 846
+ S I+ T P P V+ + D I+ R +A + G + +
Sbjct: 21635 PSQSSGIIMTRDENVP-----PIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFK 21689
Query: 847 PSVE-GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES--TPVVIQQETTGTPR 903
VE + + + S +L ++ + + +Y VE S I+ + TP
Sbjct: 21690 DGVEIEKRMNMEITDVLGSTSLF-VRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPG 21748
Query: 904 SDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVNLPGEHGQRLPISRN 959
P ++F +T K+T+ W P + +T Y ++ +
Sbjct: 21749 KVVGP----IRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQ 21804
Query: 960 TFAEVTGLSPGVTYYFKVFAVSH---GR--ESKPLTAQ-QTTKLDAPTNLQFVNETDSTV 1013
++ + L G Y F+V AV+ GR +S P+ AQ Q T DAP + N T +++
Sbjct: 21805 SYTAIK-LINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSI 21863
Query: 1014 LVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN-------LQPASEYTVSL 1066
+ W P + G + + R + + +SK P+ L +EY +
Sbjct: 21864 TLTWARPESD-GGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHV 21922
Query: 1067 VAIKGNQESPKATGVFTTLQ-------PGSSIPPYNTEVTETTIVITWTPA------PRI 1113
+A P A+G+ ++ PG T+ ++TT+ + W+ I
Sbjct: 21923 MAENAAGVGP-ASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEII 21981
Query: 1114 GFKLGVRPSQGGEAPREVTSDS---GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
G+ + + + G+ +V +++ V+ L G EY + + + + D+ V
Sbjct: 21982 GYIIEMCKADLGDW-HKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGT 22040
Query: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT----NGQQGNSLEEVVH 1226
+ + T L+ + + V ++ Y+ TPT SL +H
Sbjct: 22041 IKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIH 22100
Query: 1227 ADQSSCTFD----NLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDT 1282
S T N + +Y ++V K S+ + ++ PP + F ++ +
Sbjct: 22101 TTDSFSTLTVENCNRNDAGKYTLTVENNSGSK-SITFTVKVLDTPGPPGPITFKDVTRGS 22159
Query: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLPGTEYVVSVS 1339
+ W P +D + Y K E +S + + +L G Y VS
Sbjct: 22160 ATLMW-DAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVS 22218
Query: 1340 SVYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR----ATITGYRIR 1391
+V E P + P +D D + +S + W+ P + ITGY +
Sbjct: 22219 AVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLE 22278
Query: 1392 HHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV 1450
+ G H++ + T+ L TEY + A N S S +
Sbjct: 22279 MRQK---GSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKE 22335
Query: 1451 PR-----DLEVV--------AATPTSL---LISWDAPAVTVRYYRITYGETGGNSPVQEF 1494
P+ DL + A +P ++ + AP VT + + ET S
Sbjct: 22336 PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVS----I 22391
Query: 1495 TVPGSKSTATISGLKPGVD--YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQM---- 1548
T ++T T+ G Y +T+ ++ A K S+ I +P +
Sbjct: 22392 TTTKDRTTLTVKDSMRGDSGRYFLTL-------ENTAGVKTFSVTV-VVIGRPGPVTGPI 22443
Query: 1549 QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
+V+ V S + W + +T Y + ++G + + +T++ + L
Sbjct: 22444 EVSSVSAESCVLSWGEPKDGGGTEITNY-IVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 22502
Query: 1605 TVEYVVSVYAQNPSGESQPLVQTAV------TNIDRPKGLAFTDVDVDSIKIAWESPQGQ 1658
+EY V ++N G S+PL + P V +++ I WE P
Sbjct: 22503 YMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHD 22562
Query: 1659 VSRYRVTYSSPEDGIHELFPAPDGE----EDTAELQGLRPGSEYTVSVVALH------DD 1708
+ Y + + + + + E ++ GL G EY AL+
Sbjct: 22563 GGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKAS 22622
Query: 1709 MESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGP 1764
S+P++ + AP + T VT +++S W+ P ++ GY + P + G
Sbjct: 22623 EASRPIMA--QNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGD 22680
Query: 1765 ---MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT-LTSRPAQ--GVVTTLENVSPPR 1818
+K + V+ L YE V A + S+ ++ G VT + +PP+
Sbjct: 22681 GRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPK 22740
Query: 1819 RARVTDATETTITISWRTKTETITGFQVDAVP------ANGQTPIQRTIKPDV-----RS 1867
DA ++ R ++ + V P G + K + R+
Sbjct: 22741 AE--LDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRA 22798
Query: 1868 YTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP---SNLRFLATTPNSLLVSWQ 1924
+ +D Y T+ NA + V +D+P L T ++W
Sbjct: 22799 TAVIKFCDRSDSGKYTLTVK-NASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWS 22857
Query: 1925 PPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKN-- 1978
P+ A IT YI++ + +V P ++ +T L EY V A+
Sbjct: 22858 LPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLS-YVVTRLIKNNEYIFRVRAVNKYG 22916
Query: 1979 ---NQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFV--THPGYDTGNG 2033
+SEP++ R T+P P P I + T ++ + T P D GN
Sbjct: 22917 PGVPVESEPIVARNS-------FTIPSP----PGIPEEVGTGKEHIIIQWTKPESDGGNE 22965
Query: 2034 I 2034
I
Sbjct: 22966 I 22966
Score = 60.8 bits (146), Expect = 1e-08
Identities = 178/828 (21%), Positives = 291/828 (35%), Gaps = 149/828 (17%)
Query: 1263 IIPAVPPPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPS 1319
+I P +L T + + W P + + ++V +K + V + S
Sbjct: 6781 VIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAES 6840
Query: 1320 DNAVVLTNLLPGTEYVVSVSS-----VYEQHES-TPLRGRQKTGLDSPT-GIDFSDITAN 1372
V G EY+ VS+ E E+ P+ R K + P + +D+
Sbjct: 6841 CEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRF 6900
Query: 1373 SFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSI 1428
++ W P A IT Y I + V S T+T++ G EY +
Sbjct: 6901 GVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRV 6960
Query: 1429 VALNGREESPLLIGQQSTVSDV------------PRDLEVVAATPTSLLISWDAP----A 1472
R ++ + +G+ S + P +L T +S+ + W+ P
Sbjct: 6961 -----RAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGG 7015
Query: 1473 VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSK 1532
+ Y I E G ++ ++ + T ++GL+ G Y V A G S S
Sbjct: 7016 SPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEI 7075
Query: 1533 PISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSS--PVTGYRVTTTPKNGPGPTKTKTA 1590
+ +P+ M ++ +D + P + P TGY P PT T
Sbjct: 7076 LGPLTADDAFVEPT-MDLSAFKDGLEVIVPNPITILVPSTGY---------PRPTATWCF 7125
Query: 1591 GPDQTE----MTIEGLQPTVEYVVSVYAQNPSG----ESQPLVQTAVTNID--------R 1634
G E + ++ L E V+S ++ G + + V+T ID
Sbjct: 7126 GDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSA 7185
Query: 1635 PKGLAFTDVDVDSIKIAWESPQ----GQVSRY--------RVTYSSPEDGIHEL-FPAPD 1681
PK L F D+ DS+ + WE P ++ Y R T++ D + +L F PD
Sbjct: 7186 PKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPD 7245
Query: 1682 GEEDTAELQGLRPGSEYTVSVVALHDDMESQPL-------IGTQSTAIPAPTDLKFTQVT 1734
L G EY V A + +P + T +T P ++K+ T
Sbjct: 7246 ----------LVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRT 7295
Query: 1735 PTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKY 1788
S+ W PP ++ GY V P+ G K + + + V+GL Y
Sbjct: 7296 ANSIFLTWDPPKNDGGSRIKGYIVERCPR---GSDKWVACGEPVAETKMEVTGLEEGKWY 7352
Query: 1789 EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT-----------ITISWRTK 1837
V AL S+P++ P + D E +T+ TK
Sbjct: 7353 AYRVKALNRQGASKPSR----------PTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTK 7402
Query: 1838 TE---TITGFQVDAVPANGQTPIQRTIKPDVR----------SYTITGLQPGTDYKIYLY 1884
E T+TG P T +K D R + TI + +
Sbjct: 7403 IELPATVTG---KPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIE 7459
Query: 1885 TLNDNARSSPVV-IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEK 1939
+N R++ VV ++ P+ T S L++W PPR ++IT Y+++
Sbjct: 7460 AVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRA 7519
Query: 1940 PGSPPREVVPRPRPGV--TEATITGLEPGTEYTIYVIALKNNQKSEPL 1985
S EV + V T T L P EY V A EP+
Sbjct: 7520 TDS---EVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPV 7564
Score = 52.8 bits (125), Expect = 4e-06
Identities = 80/336 (23%), Positives = 120/336 (35%), Gaps = 46/336 (13%)
Query: 602 LQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKN-SVGRWKEA 657
++ Y S P + +T+ ++ S + W+AP S I+ Y++ R + W+E
Sbjct: 9187 VEVYDRPSPPRNLAVTDIKAE--SCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEV 9244
Query: 658 TIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
T Y I L P YE ++ ++ +YG + + D V + P
Sbjct: 9245 TNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSD-------KVVIQDPYRLPGPP 9297
Query: 718 FSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA----- 772
P V T S +VSW D Y L + + Y S A
Sbjct: 9298 GKPKVLAR------TKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKV 9351
Query: 773 ----TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPPD-PTVDQV 822
N+P LL G KY +N I E S P PP P V
Sbjct: 9352 GLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDK 9411
Query: 823 DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPE---TANSVTLSDLQPGVQ 875
+SI + W P +PI GY + +N P+ T + +L+ +
Sbjct: 9412 TKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRK 9471
Query: 876 YNITIYAVEENQESTPVVIQQETTG-TPRSDTVPSP 910
Y + AV E ES P +TTG P +D P
Sbjct: 9472 YRFRVKAVNEAGESEP----SDTTGEIPATDIQEEP 9503
Score = 43.9 bits (102), Expect = 0.002
Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 22/204 (10%)
Query: 717 PFSPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTA 772
P P+V + + +S V+SW +D ++ + VE ++EG E Q + +
Sbjct: 24421 PTGPIV-----IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISV 24475
Query: 773 TSVNIPDLLPGRKYIV-----NVYQISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTS 826
T+ I +L Y N + IS+ E S+++ S P AP PT+ V S
Sbjct: 24476 TTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDS 24535
Query: 827 IVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSV-TLSDLQPGVQYNITIY 881
VV W P A I Y + + + E +V ++ +L G++Y +
Sbjct: 24536 CVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVK 24595
Query: 882 AVEENQESTPVVIQQETTGTPRSD 905
ES I + TP+SD
Sbjct: 24596 CENLGGESEWSEISEPI--TPKSD 24617
Score = 41.2 bits (95), Expect = 0.012
Identities = 92/413 (22%), Positives = 157/413 (38%), Gaps = 51/413 (12%)
Query: 1285 VTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSV 1341
++W PP +TN++V K + +S + S + NL Y VS+
Sbjct: 24437 ISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQ 24496
Query: 1342 YEQHESTPLRGRQKTGLDSPTGID-------FSDITANSFTVHWIAPRATITGYRIRHHP 1394
S PL + SP + +T +S V W P A+ G +IR++
Sbjct: 24497 NTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAW-KPPASDGGAKIRNYY 24555
Query: 1395 EHFSGRPREDRVPHSRNSITLT-----NLTPGTEYVVSIVA--LNGREESPLLIGQQSTV 1447
+ + + + I T NL G EY + L G E + +
Sbjct: 24556 LEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPK 24615
Query: 1448 SDVP----------RDLEVVAATPTSLLISWDA-PAVTVRYYRITYGET----GGNSPVQ 1492
SDVP R+L V + +L+ P V++YR G+ G +Q
Sbjct: 24616 SDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYR--QGKEIIADGLKYRIQ 24673
Query: 1493 EFTVPGSKSTATISGLKPGVDYTITVYAV--TGRGDSPASSKPISINYRTEIDKPSQMQ- 1549
EF G I+ + D TVY V T +G S + + + + +I P ++
Sbjct: 24674 EFK--GGYHQLIIASV---TDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEG 24728
Query: 1550 ---VTDVQDNSISVKWLPSSS---PVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
V ++ +S+K +P S PV ++ + G + + + G++
Sbjct: 24729 MGAVHALRGEVVSIK-IPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVE 24787
Query: 1604 PTVEYVVSVYAQNPSGESQPLVQTAVTNI-DRPKGLAFTDVDVDSIKIAWESP 1655
V A+N G Q V+ V ++ D P+G+ +DV DS+ + W P
Sbjct: 24788 RKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEP 24840
Score = 39.3 bits (90), Expect = 0.046
Identities = 46/194 (23%), Positives = 75/194 (38%), Gaps = 22/194 (11%)
Query: 2062 PPTTATPIRH-RPRPYPPNVGQEALSQTTISWAPFQD-----TSEYIISCHPVGTDEEPL 2115
P T TP+ P PP V S ++SW+ +D + Y I TD+
Sbjct: 24014 PVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVR 24073
Query: 2116 QFRVPGTSTSATLTGLTRGATYNIIVEALKD---QQRHKVREEVVTVGNSVNEGLNQPTD 2172
+ T+T T+TGL A Y + A D + E VV + ++P+
Sbjct: 24074 HNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVV-----CKDPFDKPSQ 24128
Query: 2173 DSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEK 2232
+ ++S +V +WE+ G K + LG+ + + S W N K
Sbjct: 24129 PGELEILSISKDSVTLQWEKPECDGGK---EILGYWVEYRQSGDSAWKKSNKERIK---- 24181
Query: 2233 WDRQGENGQMMSCT 2246
D+Q G ++ T
Sbjct: 24182 -DKQFTIGGLLEAT 24194
Score = 37.7 bits (86), Expect = 0.13
Identities = 36/131 (27%), Positives = 53/131 (40%), Gaps = 8/131 (6%)
Query: 894 IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGE 949
I Q+T +D PR ++ +V+ V + WT P S +T Y V+ E
Sbjct: 24804 IDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATT--AE 24861
Query: 950 HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ--TTKLDAPTNLQFVN 1007
R+ +R T V L +Y F+V A + SKP + TK D + +
Sbjct: 24862 RWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDE 24921
Query: 1008 ETDSTVLVRWT 1018
E D T V T
Sbjct: 24922 EVDETREVSMT 24932
Score = 35.0 bits (79), Expect = 0.87
Identities = 38/169 (22%), Positives = 71/169 (42%), Gaps = 17/169 (10%)
Query: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL-PSS---SPVTGYRV 1574
Y V + K + ++ D P ++V+DV +S+++ W P+S S +T Y V
Sbjct: 24794 YVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIV 24853
Query: 1575 TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL--VQTAVTNI 1632
+ A +T T+ L Y V A+N G S+P + +T
Sbjct: 24854 EKCATTAERWLRVGQA--RETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKE 24911
Query: 1633 DRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPD 1681
D+ + + + D +VD + +VS + ++SS ++ + A D
Sbjct: 24912 DKTRAMNY-DEEVDETR--------EVSMTKASHSSTKELYEKYMIAED 24951
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 154 bits (388), Expect = 1e-36
Identities = 299/1365 (21%), Positives = 509/1365 (37%), Gaps = 169/1365 (12%)
Query: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPI-QWNAPQP---SHISKYILRW 645
YG G+ +P+ S + P I E H I QW P+ + IS Y++
Sbjct: 22848 YGPGVPV-ESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDK 22906
Query: 646 RPKNSVGRWKEATIPGHLNSYTIK--GLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTS 703
R K S+ RW + +K L G Y+ ++ ++ G+ E +
Sbjct: 22907 REKKSL-RWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSE--------- 22956
Query: 704 TPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELS-EEGDE 762
SN ++ ++P ++ V + T S ++W V Y L +E D
Sbjct: 22957 ---ASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDT 23013
Query: 763 PQYLDLPSTATSVN----IPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT 818
Q+ + + AT N +PDL G+KY V ++ G S ++ + P
Sbjct: 23014 DQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPD 23073
Query: 819 VDQVDDT--SIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP-----ETANSVTLSDLQ 871
++ DD ++ +R + P + S ++L +T S +L +
Sbjct: 23074 LELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVD 23133
Query: 872 PGVQYNITIYAVE-ENQE----STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
+Y+ Y +E ENQ +T +V +T G P P ++ EV+ VTI
Sbjct: 23134 KVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPG-------PCP-SVKVKEVSRDSVTIT 23185
Query: 927 WTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH 982
W P + V Y V+ + S+ T ++GL G YYF+V +
Sbjct: 23186 WEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSK-TLYRISGLVEGTMYYFRVLPENI 23244
Query: 983 GRESKPLTAQQTTKLD----APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLT 1034
+P + P L+ V+ T STV + W P +++TGY L
Sbjct: 23245 YGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEA--C 23302
Query: 1035 RRGQPRQYNV---GPSVSKYPLRNLQPASEYTVSLVAI--KGNQESPKATGVFTTLQPGS 1089
+ G R V P+V ++ + +L +Y + A KG E P+ T T+Q
Sbjct: 23303 KAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSE-PRETVTAVTVQDLR 23361
Query: 1090 SIPPYNTEV-------------TETTIVITWTPAPRIG-FKLGVRPSQGGEAPREVTSDS 1135
+P + E I I P P F G + + E +
Sbjct: 23362 VLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKV 23421
Query: 1136 GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
+ + T YT+++ I ++ PPT D +T+SW
Sbjct: 23422 AKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISW 23481
Query: 1196 ERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV----- 1247
E ++GY + + + E V +S+ F L+ G EY V
Sbjct: 23482 EPPELDGGAPLSGYVVEQRDAHRPGWLPVSESV--TRSTFKFTRLTEGNEYVFRVAATNR 23539
Query: 1248 YTVKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYS 1303
+ + +S I +P PP L+ ++ D M +TW PP +T ++V
Sbjct: 23540 FGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERK 23599
Query: 1304 PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR-GRQKTGLD--- 1359
V+ + V + + T L G EY V+++ + P R + +D
Sbjct: 23600 EVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIA 23659
Query: 1360 ---SPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNS 1412
P +D T S ++ W P + +TGY I + + P
Sbjct: 23660 PPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIRE 23719
Query: 1413 ITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAAT--PTSLLISWDA 1470
TLT+L G EY ++A N G ++VP ++V P L
Sbjct: 23720 YTLTHLPQGAEYRFRVLACNA--------GGPGEPAEVPGTVKVTEMLEYPDYELDERYQ 23771
Query: 1471 PAVTVRY---YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
+ VR R+T G P+ ++T G + + + + +T V RGDS
Sbjct: 23772 EGIFVRQGGVIRLTIPIKGKPFPICKWTKEG-QDISKRAMIATSETHTELVIKEADRGDS 23830
Query: 1528 ---------PASSKPISINYRTEIDKPSQ----MQVTDVQDNSISVKWLPSS----SPVT 1570
K + I R I P+ ++ D+Q S+ V W P + + +
Sbjct: 23831 GTYDLVLENKCGKKAVYIKVRV-IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADIL 23889
Query: 1571 GYRVTT--TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ-- 1626
GY + PK ++ G T + ++GL+ VEY V A+N G S+PL
Sbjct: 23890 GYILERREVPKAAWYTIDSRVRG---TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEE 23946
Query: 1627 --TAVTNIDRPKGLA----FTDVDVDSIKIAWESPQGQ-VSRYRVTYSSPEDGIHELFPA 1679
T T ++ P+ + DV S+ ++W P+ SR Y ++ + +
Sbjct: 23947 PVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVR 24006
Query: 1680 PDGEEDTAEL---QGLRPGSEYTVSVVALHD------DMESQPLIGTQSTAIPA-PTDLK 1729
+ + T + GL P +EY ++A +D S+P++ P+ P +L+
Sbjct: 24007 HNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELE 24066
Query: 1730 FTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVA 1785
++ S++ QW P ++ GY V + K + GL+ A
Sbjct: 24067 ILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEA 24126
Query: 1786 TKYEVSVYALKDTLTSRP---AQGVVTTL-ENVSPPRRARVTDAT 1826
T+YE V+A +T SRP A + T L +P R + D T
Sbjct: 24127 TEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVT 24171
Score = 148 bits (373), Expect = 7e-35
Identities = 289/1429 (20%), Positives = 524/1429 (36%), Gaps = 170/1429 (11%)
Query: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
D+T T+ ++ + + P S + ++ + ++SW + Y
Sbjct: 12993 DYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 13052
Query: 756 LSE-EGDEPQYLDLPSTA--TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQ 807
+ + E P + + +T TS ++ L+ G +Y N Y + + ++ +
Sbjct: 13053 VDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNP 13112
Query: 808 TTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNL-PETA 862
P P + + + V W P +PITGY + + + T++N P
Sbjct: 13113 YDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIE 13172
Query: 863 NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK 922
++ + LQ G +Y + A+ + P + P + + T
Sbjct: 13173 RTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSS 13232
Query: 923 VTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKV 977
V++ W P S + GY V+V + LP + + T EVTGL Y F+V
Sbjct: 13233 VSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRV 13292
Query: 978 FAVSHGRESKP-----------LTAQQTTKLDAPTNLQFVNETDST----VLVRWTPPRA 1022
+AV+ S P + +LDA + T V V+ PP
Sbjct: 13293 YAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPP-P 13351
Query: 1023 QITGYRLTVGLTRR-GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
+IT + V L R G + + + N A +Y ++L G +E V
Sbjct: 13352 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13411
Query: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDS 1135
T PG + E+++ + +TW P +P I + + R ++ T S
Sbjct: 13412 LDT--PGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECS 13469
Query: 1136 G-SIVVSGLTPGVEYVYTIQVLRD------GQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
S V+ L G Y + + + G+ RDA V TP P +L + + +
Sbjct: 13470 KTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDA--VKASQTP-GPVVDLKVRSVSKS 13526
Query: 1189 GVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
++ W++ + I GY + + N + V+ + + +L+ G EY
Sbjct: 13527 SC-SIGWKKPHSDGGSRIIGYVVDFLT----EENKWQRVMKSLSLQYSAKDLTEGKEYTF 13581
Query: 1246 SVYTVKDDKESVPISDTIIP---AVPPPTDLRFTNIGPDT-------------MRVTWAP 1289
V ++ E P T++ V P DL+ PD + + P
Sbjct: 13582 RVSAENENGEGTPSEITVVARDDVVAPDLDLKGL---PDLCYLAKENSNFRLKIPIKGKP 13638
Query: 1290 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL-------PGTEYVVSVSSVY 1342
PS+ S K E+ +A + +++ V T L+ +Y +++ +V
Sbjct: 13639 APSV---------SWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVA 13689
Query: 1343 EQHEST-PLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEH 1396
E T ++ K G+ PTG I F ++TA + T+ W P+ + IT Y I +
Sbjct: 13690 GTKEGTISIKVVGKPGI--PTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNY-ILEKRDS 13746
Query: 1397 FSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------GREESPLLIGQQSTVSDV 1450
+ + + + +T L G EY + A N G + P++ V D
Sbjct: 13747 VNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDA 13806
Query: 1451 PRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATIS 1506
P +V S+ ++W P T + Y + + E + P ++
Sbjct: 13807 PPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVT 13866
Query: 1507 GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP-- 1564
GL G++Y V A+ G S + ID P + +V ++ NS+++ W
Sbjct: 13867 GLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPK 13926
Query: 1565 --SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1622
+TGY V K + T+ L +Y + A+N +G
Sbjct: 13927 YDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAIS 13986
Query: 1623 PLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQV----------------SRYRVTY 1666
++ T I + + A T V +IK G S +
Sbjct: 13987 APSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGK 14046
Query: 1667 SSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT 1726
I ++ P T + + EYT++ + P P
Sbjct: 14047 DIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGP-PG 14105
Query: 1727 DLKFTQVTPTSLSAQWTPPNVQLTGYRVR--VTPKEKTGPMKEINLAPDSSSV--VVSGL 1782
++ + V+ + WTPP ++ G ++ + K +T + ++ D S V + L
Sbjct: 14106 PVEISNVSAEKATLTWTPP-LEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKL 14164
Query: 1783 MVATKYEVSVYALKDTLTSRPAQG----VVTTLENVSPPRRARVTDATETTITISWRTKT 1838
+ +Y V A+ P Q +V PP + V++ T+ T T+SW+
Sbjct: 14165 IQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPV 14224
Query: 1839 E----TITGFQVDAVPANGQTPIQRTIKPDVRSY--TITGLQPGTDYKIYLYTLN----- 1887
+ ITG+ V+ + R IK V +TGLQ G+ Y+ + N
Sbjct: 14225 DDGGSEITGYHVERREKKSLRWV-RAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 14283
Query: 1888 --DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPG 1941
A S ++ DA+ PSN TT S ++W P ITGY+++++K G
Sbjct: 14284 PPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVG 14343
Query: 1942 SPPREVVPRPRPG----VTEATITGLEPGTEYTIYVIALKNNQKSEPLI 1986
E + G +T+ + L+ +Y + A+ + EP +
Sbjct: 14344 D---EAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAV 14389
Score = 145 bits (367), Expect = 4e-34
Identities = 292/1351 (21%), Positives = 505/1351 (37%), Gaps = 184/1351 (13%)
Query: 780 LLPGRKYIVNVYQISEDG-----EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP 834
L+ +YI V +++ G E I++ + T P P P I+++W++P
Sbjct: 22832 LIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKP 22891
Query: 835 QAP----ITGYRIVYSPSVEGSSTELNLPETANSVTL--SDLQPGVQYNITIYAVEENQE 888
++ I+ Y + T +N L + L G Y + AV
Sbjct: 22892 ESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGN 22951
Query: 889 STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
S P + S T P + V+ T +++ WT P + + GY +++
Sbjct: 22952 SEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEK 23011
Query: 945 NLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA----QQTTKLDA 999
+ + + RNT V L G Y F+V AV+ S+ + + +++
Sbjct: 23012 DTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEI 23071
Query: 1000 PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP-----------RQYNVGPSV 1048
P +L+ ++ TV +R RL V ++ R P + +
Sbjct: 23072 P-DLELADDLKKTVTIRAG------ASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTT 23124
Query: 1049 SKYPLR-----NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI 1103
Y L N A +YT+ G + + V+ T P S+ EV+ ++
Sbjct: 23125 ESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKV--KEVSRDSV 23182
Query: 1104 VITWT------PAPRIGFKLGVRPSQGGEAPREVTSDSGSIV-VSGLTPGVEYVYTIQ-- 1154
ITW AP + + R + T S ++ +SGL G Y + +
Sbjct: 23183 TITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPE 23242
Query: 1155 ----VLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYR 1207
+ + DA +V++V PL P ++ T +T++WE+ +TGY
Sbjct: 23243 NIYGIGEPCETSDAVLVSEV--PLVPAKLEVVDVTKST--VTLAWEKPLYDGGSRLTGYV 23298
Query: 1208 ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY-----------------NVSVYTV 1250
+ ++ + + T +L+ G +Y V+ TV
Sbjct: 23299 LEACKAGTERWMKVV-TLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTV 23357
Query: 1251 KD-------DKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYS 1303
+D D ++P +PA P +L + + PPP+ F
Sbjct: 23358 QDLRVLPTIDLSTMPQKTIHVPA-GRPVEL--------VIPIAGRPPPAASW--FFAGSK 23406
Query: 1304 PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHESTPLRGRQKTGLDSPT 1362
++E E + + T + EY + + +V E+ + K G PT
Sbjct: 23407 LRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPG--PPT 23464
Query: 1363 G-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSG-RPREDRVPHSRNSITLT 1416
G I +I A S T+ W P A ++GY + H G P + V +R++ T
Sbjct: 23465 GPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESV--TRSTFKFT 23522
Query: 1417 NLTPGTEYVVSIVALN----GREESPLLIGQQSTVS--DVPRDLEVVAATPTSLLISWDA 1470
LT G EYV + A N G +I +S++ P L++ + + ++W
Sbjct: 23523 RLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYP 23582
Query: 1471 P----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD 1526
P V Y + E + V+ VP + + +GL G++Y V A+ RG
Sbjct: 23583 PEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGS 23642
Query: 1527 SPAS--SKPI-SINYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPK 1579
S SKPI +++ KP +VTD S+S+ W S VTGY +
Sbjct: 23643 GKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKV 23702
Query: 1580 NGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLA 1639
+ TK T E T+ L EY V A N G +P + L
Sbjct: 23703 DQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEM--LE 23760
Query: 1640 FTDVDVDS-IKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEY 1698
+ D ++D + QG V R + I + +G+ D ++ + +
Sbjct: 23761 YPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKW--TKEGQ-DISKRAMIATSETH 23817
Query: 1699 TVSVVALHDDMES------------QPLIGTQSTAIPAPTD----LKFTQVTPTSLSAQW 1742
T V+ D +S + + + I +P L++ + S+ W
Sbjct: 23818 TELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSW 23877
Query: 1743 TPP----NVQLTGYRV--RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1796
PP + GY + R PK I+ +S+VV GL +Y V A
Sbjct: 23878 RPPADDGGADILGYILERREVPK---AAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAEN 23934
Query: 1797 DTLTSRP--AQGVVTTLENVSPPRRA----RVTDATETTITISW-RTKTE---TITGFQV 1846
S+P ++ VT ++PP V D T++++++SW R K + +TG+ +
Sbjct: 23935 QFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYI 23994
Query: 1847 DAVPANGQTPIQRTIKPDVRS--YTITGLQPGTDYKIYLYTLND------NARSSPVVI- 1897
+ + ++ K + + YT+TGL P +Y+ + ND + S PVV
Sbjct: 23995 ERKETSTDKWVRHN-KTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCK 24053
Query: 1898 DASTAIDAPSNLRFLATTPNSLLVSWQPPRA----RITGYIIKYEKPGSPPREVVPRPRP 1953
D P L L+ + +S+ + W+ P I GY ++Y + G + + R
Sbjct: 24054 DPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERI 24113
Query: 1954 GVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
+ TI GL TEY V A S P
Sbjct: 24114 KDKQFTIGGLLEATEYEFRVFAENETGLSRP 24144
Score = 135 bits (339), Expect = 6e-31
Identities = 320/1486 (21%), Positives = 522/1486 (35%), Gaps = 215/1486 (14%)
Query: 771 TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVR 830
T S++ D KYI+ + S G +S ++ P P + V +V S +
Sbjct: 17706 TQLSIDNCDRNDAGKYILKLENSS--GSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLV 17763
Query: 831 WSRP----QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN 886
W P A + Y I S + ++ + S + +L G Y + A E
Sbjct: 17764 WEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEF 17823
Query: 887 QESTPVVIQQETTGTPRSDTVPSPRD-LQFVEVTDVKVTIMWTPPE----SAVTGYRVDV 941
PV ET ++ PSP + +V+ ++MW PE S V GY V++
Sbjct: 17824 GVGVPV----ETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEM 17879
Query: 942 IPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-----------LT 990
P E + S+ A VTGLS G Y F+V A + +S P LT
Sbjct: 17880 QPKGT--EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLT 17937
Query: 991 AQQTTKLDAPT-NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP----RQYNVG 1045
Q + KL T ++Q + + V P R + + G+P + NV
Sbjct: 17938 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRP--------RPNISWVKDGEPLKQTTRVNVE 17989
Query: 1046 PSVSKYPLR----NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN-TEVTE 1100
+ + L N +YTV+ G + + V +PG + P EV+
Sbjct: 17990 ETATSTVLHIKEGNKDDFGKYTVTATNSAGT--ATENLSVIVLEKPGPPVGPVRFDEVSA 18047
Query: 1101 TTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYV 1150
+VI+W P G G + S R+ T+ + +V ++ L G EY
Sbjct: 18048 DFVVISWEPPAYTG---GCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQ 18104
Query: 1151 YTIQVLRDGQERDAPIVNKVVTPLSP-----PTNLHLEANPDTGVLTVSWERSTTPD--- 1202
+ I + + AP+ +K V P P + + V W
Sbjct: 18105 FRI-FAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTK 18163
Query: 1203 ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN--VSVYTVKDDKESVPIS 1260
I GY + N L + D T L GLEY VS + + +S
Sbjct: 18164 IIGYHLEQKEKNSILWVKLNKTPIQDTKFKT-TGLDEGLEYEFKVSAENIVGIGKPSKVS 18222
Query: 1261 DTIIPAVP--PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELS 1315
+ + P PP I + + + W P +T ++V K+ D +
Sbjct: 18223 ECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEK---KDLPDGRWMK 18279
Query: 1316 ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFT 1375
S TN+L TE+ VS V +Q + R G S ITA
Sbjct: 18280 AS-------FTNVLE-TEFTVS-GLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARD-- 18328
Query: 1376 VHWIAPRATITG-YR---IRHHPEHF------SGRPREDRV--------------PHSRN 1411
AP A++ Y+ + H E F G+P D V ++
Sbjct: 18329 -EIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKS 18387
Query: 1412 SITLTNL-------TPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSL 1464
+I T L T G +Y++ + + G + P+ + L+V T
Sbjct: 18388 TIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKC 18447
Query: 1465 LISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
++W+ P + +Y I ET S Q T + + ++ L PG +Y V A
Sbjct: 18448 YLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYK-VTKLLPGNEYIFRVMA 18506
Query: 1521 VTGRG-DSPASSKPISI-NYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRV 1574
V G P S P++ N PS +V+ + +S+ V W + + GY +
Sbjct: 18507 VNKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYIL 18566
Query: 1575 TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT------- 1627
K G TK + + GL Y V A+N +G +P +
Sbjct: 18567 EKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACD 18626
Query: 1628 AVTNIDRPKGLAFTDVDVDSIKIAWESP----QGQVSRYRVTYSSPEDGIHELFPAPDGE 1683
A+ P TD S+ +AW P V Y V P G
Sbjct: 18627 ALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGL 18686
Query: 1684 EDTA-ELQGLRPGSEYTVSVVALHDDMESQPL-----IGTQSTAIPAPTDLKFTQVTPTS 1737
+ + L+ +EY + A++ + +P + Q P +L
Sbjct: 18687 QGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVV 18746
Query: 1738 LSAQWTPPNVQLTGYRVRVTPKEKTGPM----KEINLAPDSSSVVVSGLMV------ATK 1787
L A T R+ VT K + P K + D + + V+ T+
Sbjct: 18747 LRASAT--------LRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTR 18798
Query: 1788 YEVSVY--ALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETI 1841
++ Y L++ S+ A V L++ S P + + + ++T+SW I
Sbjct: 18799 FDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKI 18858
Query: 1842 TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1901
T + V+ + T ++ I LQ G Y + N+ P
Sbjct: 18859 TNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPV 18918
Query: 1902 AIDAP----SNLRFLATTPNSLLVSWQPPRA----RITGYIIKYEKPGSPPREVVPRPRP 1953
+ P + + T N+ + W+ P + +ITGY+++ + GS + +
Sbjct: 18919 KVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVK- 18977
Query: 1954 GVTEATITGLEPGTEYTIYVIALKNNQKSE------PLIGRKKTDELPQLVTLPHP--NL 2005
EATI+GL G EY V A+ +S+ P+I R E+ V LP N+
Sbjct: 18978 -TLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIAR--DIEIKPSVELPFHTFNV 19034
Query: 2006 HGPEIL--DVP---------------STVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQ 2048
E L DVP T+++T V T + + S + VG
Sbjct: 19035 KAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEAS--KEDVGT 19092
Query: 2049 QMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAP 2094
+ + T P T + P P + + + TISW P
Sbjct: 19093 YELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNP 19138
Score = 133 bits (334), Expect = 2e-30
Identities = 288/1457 (19%), Positives = 519/1457 (35%), Gaps = 224/1457 (15%)
Query: 728 VTEITASSFVVSWVSASDTVSGFRVEY--ELSEEGDEP-QYLDLPSTATSVNIPDLLPGR 784
V+ ++A S V+SW D Y E E G Q ++ T + + L
Sbjct: 22378 VSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYM 22437
Query: 785 KYIVNV-----YQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPIT 839
+Y V + +S+ E + I++ P AP P V V ++ +RW P
Sbjct: 22438 EYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGG 22497
Query: 840 GYRIVYSPSVEGSST-----ELNLPETANSVTLSDLQPGVQYNITIYAV------EENQE 888
I Y + +T E +P + ++ L G++Y YA+ + ++
Sbjct: 22498 SKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEA 22557
Query: 889 STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
S P++ Q + V +P + +VT V+++W+ P S V GY ++ PV
Sbjct: 22558 SRPIMAQ---------NPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPV 22608
Query: 945 NLPGEHGQRLP----ISRNTFAEVTGLSPGVTYYFKVFA------VSHGRESK-PLT--- 990
+ G+ G+ L I + F VT LS G TY F+V A +S G ES P+T
Sbjct: 22609 SEVGD-GRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRD 22667
Query: 991 --AQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR-------- 1040
A +LDA + V + LV A + G + +G
Sbjct: 22668 EYAPPKAELDARLHGDLVTIRAGSDLVL----DAAVGGKPEPKIIWTKGDKELDLCEKVS 22723
Query: 1041 -QYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTL--QPGSSIPPYNTE 1097
QY + + + + +YT+++ N KA V + PG +
Sbjct: 22724 LQYTGKRATAVIKFCDRSDSGKYTLTVK----NASGTKAVSVMVKVLDSPGPCGKLTVSR 22779
Query: 1098 VTETTIVITWTPAPRIGFKLGVRPSQGGEAP-------REVTSDSGSIVVSGLTPGVEYV 1150
VT+ + W+ P + G A R TS ++V G P + YV
Sbjct: 22780 VTQEKCTLAWS-----------LPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYV 22828
Query: 1151 YTIQVLRDGQE----------------RDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVS 1194
T +++++ + PIV + + P + E + +
Sbjct: 22829 VT-RLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQ 22887
Query: 1195 WERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK 1251
W + + +I+ Y + + + + + +L G +Y V V
Sbjct: 22888 WTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVN 22947
Query: 1252 DDKESVP--ISDTIIPAVP-----PPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSP 1304
S P S+ I P PP+ R + ++ + W P D +V Y
Sbjct: 22948 AAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKP-MYDGGTDIVGYVL 23006
Query: 1305 VKNEEDVAE-----LSISPSDNAVVLTNLLPGTEYVVSVSSV----YEQHESTPLRGRQK 1355
E+D + + + + + +L G +Y V++V ++ +
Sbjct: 23007 EMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPV 23066
Query: 1356 TGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP-------- 1407
++ P ++ +D + T+ A + R P + D
Sbjct: 23067 ERIEIPD-LELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTE 23125
Query: 1408 -HSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLI 1466
+S + N +Y + +G++ + +L+ T P ++V + S+ I
Sbjct: 23126 SYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCP-SVKVKEVSRDSVTI 23184
Query: 1467 SWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA-- 1520
+W+ P + V Y + E + + T SK+ ISGL G Y V
Sbjct: 23185 TWEIPTIDGGAPVNNYIVEKREAAMRA-FKTVTTKCSKTLYRISGLVEGTMYYFRVLPEN 23243
Query: 1521 VTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTT 1576
+ G G+ +S + ++ + P++++V DV +++++ W S +TGY +
Sbjct: 23244 IYGIGEPCETSDAVLVSEVPLV--PAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEA 23301
Query: 1577 TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPK 1636
K T P E T+ L +Y+ + AQN G S+P + +
Sbjct: 23302 CKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLR 23361
Query: 1637 GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDG--EEDTAELQGLRP 1694
L D+ K P G+ + + F A E + ++
Sbjct: 23362 VLPTIDLSTMPQKTI-HVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTK 23420
Query: 1695 GSEYTVSVVALHDD----MESQPLIGTQSTAI---------PAPTDLKFTQVTPTSLSAQ 1741
++ T+ + D +E + + GT S I P +K ++ TS++
Sbjct: 23421 VAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITIS 23480
Query: 1742 WTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1797
W PP + L+GY V + G + P S SV S E + Y +
Sbjct: 23481 WEPPELDGGAPLSGYVVEQRDAHRPGWL------PVSESVTRSTFKFTRLTEGNEYVFRV 23534
Query: 1798 TLTSRPAQGVVTTLENVS---------PPRRARVTDATETTITISWRTKTET----ITGF 1844
T+R G E + PP ++ D + +T++W + +TG+
Sbjct: 23535 AATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGY 23594
Query: 1845 QVDAVPANGQTPIQRTIKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSP-------VV 1896
V+ ++ P + Y TGL G +Y+ + +N P V
Sbjct: 23595 IVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVA 23654
Query: 1897 IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPR 1952
+D P N R TT S+ ++W P +++TGY+I+ +K
Sbjct: 23655 MDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTP 23714
Query: 1953 PGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILD 2012
+ E T+T L G EY V+A EP +
Sbjct: 23715 TKIREYTLTHLPQGAEYRFRVLACNAGGPGEP--------------------------AE 23748
Query: 2013 VPSTVQKTPFVTHPGYD 2029
VP TV+ T + +P Y+
Sbjct: 23749 VPGTVKVTEMLEYPDYE 23765
Score = 132 bits (332), Expect = 4e-30
Identities = 282/1282 (21%), Positives = 484/1282 (37%), Gaps = 198/1282 (15%)
Query: 611 PVEVFITETPSQPNSHPIQWNAP---QPSHISKYILRWRPKNSVGRWKEATIPGHLNSYT 667
PV V + E +S + W P S I Y+++ R W T S+
Sbjct: 13418 PVNVTVKEISK--DSAYVTWEPPIIDGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFR 13474
Query: 668 IKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSES 727
+ L+ G Y ++ + +YG + T + V TP P+V
Sbjct: 13475 VANLEEGKSYFFRVFAENEYGIGDPGE------------TRDAVKASQTP-GPVVDLK-- 13519
Query: 728 VTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
V ++ SS + W + G+ V++ L+EE + + S + + DL G
Sbjct: 13520 VRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMK--SLSLQYSAKDLTEG 13576
Query: 784 RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITG 840
++Y V +E+GE + T PD + + D + + + R + PI G
Sbjct: 13577 KEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKG 13636
Query: 841 YRIVYSPSVE--------GSSTELNLPETANSVTLS--DLQPGV--QYNITIYAVEENQE 888
+PSV + T +++ +A + TL D Q +Y IT+ V +E
Sbjct: 13637 KP---APSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13693
Query: 889 STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
T I + G P T P ++F EVT +T+ W PP+ S +T Y ++
Sbjct: 13694 GT---ISIKVVGKPGIPTGP----IKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDS 13746
Query: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKL-D 998
+ + TF VT L G+ Y F+V + V G +S+P+ A+ + D
Sbjct: 13747 VNNKWVTCASAVQKTTF-RVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPD 13805
Query: 999 APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP-SVSKYPL 1053
AP V+ +V + WT P+ + ITGY L ++ N P + + +
Sbjct: 13806 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV 13865
Query: 1054 RNLQPASEYTVSLVAIK----GNQESPKATGVFTTLQPGSSIPPYNTEV---TETTIVIT 1106
L EY ++AI G P V L P PP EV T ++ +
Sbjct: 13866 TGLTEGLEYEFRVMAINLAGVGKPSLPSEPVV--ALDPID--PPGKPEVINITRNSVTLI 13921
Query: 1107 WT-PAPRIGFKLGVR-------PSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD 1158
WT P G KL PS+ V + V+ L G +Y + I+
Sbjct: 13922 WTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNT 13981
Query: 1159 GQERDAPIVN----------KVVTPLSPPT---NLHLEANPDTGVLTV-----------S 1194
AP + + T + PT L ++A DT VL S
Sbjct: 13982 AGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAG-DTIVLNAISILGKPLPKSS 14040
Query: 1195 WERS----TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
W ++ DIT +IT+TPT+ +++ D T +P + V V
Sbjct: 14041 WSKAGKDIRPSDIT--QITSTPTSSML--TIKYATRKDAGEYTITATNP---FGTKVEHV 14093
Query: 1251 KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEED 1310
K T++ PP + +N+ + +TW PP D + + Y K E
Sbjct: 14094 KV---------TVLDVPGPPGPVEISNVSAEKATLTWTPPLE-DGGSPIKSYILEKRETS 14143
Query: 1311 VAELSISPSDNAV---VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD------SP 1361
++ D V T L+ G EY+ VS+V + P++ +D P
Sbjct: 14144 RLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPP 14203
Query: 1362 TGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
+ S++T N+ TV W P + ITGY + + R + P S +T
Sbjct: 14204 EKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTG 14263
Query: 1418 LTPGTEYVVSIVALNGREESP-------LLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
L G+ Y + A N P +L+ + P + V T S ++W
Sbjct: 14264 LQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGK 14323
Query: 1471 P----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKPGVDYTITVYAVTGRG 1525
P + + Y + + + G + +++ T + T + L+ Y + A+ G
Sbjct: 14324 PHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAG 14383
Query: 1526 -DSPASSKPISINYR---TEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNG 1581
PA + I R + + ++++ T V +S++ VT T N
Sbjct: 14384 VGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNI 14443
Query: 1582 PGPTKTKTAGPDQTEMTIE---GLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRP-KG 1637
+ + + I T ++V+++ +NP+G+ V V + P
Sbjct: 14444 NLKNRANIENTESFTLLIIPECNRYDTGKFVMTI--ENPAGKKSGFVNVRVLDTPGPVLN 14501
Query: 1638 LAFTDVDVDSIKIAWESP----QGQVSRY--------RVTYSSPEDGIHELFPAPDGEED 1685
L TD+ DS+ + W+ P +++ Y R +YS+ H+
Sbjct: 14502 LRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKC--------- 14552
Query: 1686 TAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ---STAIPAPTD-LKFTQVTPTSLSAQ 1741
T ++ GL G EY V+A ++ +P T+ ++ P+P D L +T +++S
Sbjct: 14553 TYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLA 14612
Query: 1742 WTPP----NVQLTGYRVRVTPK 1759
W P ++TGY + K
Sbjct: 14613 WPKPKHDGGSKITGYVIEAQRK 14634
Score = 129 bits (324), Expect = 3e-29
Identities = 296/1415 (20%), Positives = 523/1415 (36%), Gaps = 202/1415 (14%)
Query: 728 VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT----SVNIPDLLPG 783
+ ++++ V W D G ++ + E+ + + + +AT + L+ G
Sbjct: 11933 IVDVSSDRCTVCWDPPEDD-GGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEG 11991
Query: 784 RKYIVNVYQISEDG-----EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ--- 835
+YI V ++ G E +++ ++ P P P V +V + V W+ P+
Sbjct: 11992 NEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDG 12051
Query: 836 -APITGYRIVYSPSVEGSSTELN---LPETANSVTLSDLQPGVQYNITIYAVEENQESTP 891
ITGY + +N +PE V +L P +Y + A E P
Sbjct: 12052 GKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKV--QNLLPDHEYQFRVKAENEIGIGEP 12109
Query: 892 VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNL- 946
+ + + P + + V+ T +T+ W P + + GY V++ P
Sbjct: 12110 SLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIAD 12169
Query: 947 --PGEHGQRL----PISRNTFAEVTGLSPGVTYYFKVFA---VSHGRESKPLTAQQTTKL 997
P E +R + R F VT L Y F+V A V GR ++ A + ++
Sbjct: 12170 ASPDEGWKRCNAAAQLVRKEFT-VTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEI 12228
Query: 998 DAPTNLQFVNETDSTVLVRWT-----------PPRAQITGYRLTV-GLTRRGQPRQYNVG 1045
P + V+VR P ++T ++ + + R+GQ +
Sbjct: 12229 LEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDT- 12287
Query: 1046 PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105
+ P + +Y+++LV G + V T P S + ++VT+T+ +
Sbjct: 12288 MAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKV--SDVTKTSCHV 12345
Query: 1106 TWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQV 1155
+W P G G + + RE + S V V+ L PG EY + +
Sbjct: 12346 SWAPPENDG---GSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTA 12402
Query: 1156 LRD---GQERDAPIVNKVVTPLS---PPTNLHLEANPDTGVLTVSWE---RSTTPDITGY 1206
+ + G D P PLS PP L + T++W R I GY
Sbjct: 12403 VNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSA-TLAWLPPLRDGGAKIDGY 12461
Query: 1207 RITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKESVPISD 1261
IT+ Q + E S L G +Y V V +E+ + +
Sbjct: 12462 -ITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYE 12520
Query: 1262 TIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK---NEEDV---AELS 1315
+PP + P+ + + I+ + + K E++V + L+
Sbjct: 12521 AKEQLLPPKI------LMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLA 12574
Query: 1316 ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP----TGIDFSDITA 1371
+ +D++ +L + S E T + + +D+P D SDI A
Sbjct: 12575 VHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDA 12634
Query: 1372 NSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH----SRNSITLTNLTPGTEYVVS 1427
++ ++ W P G I ++ R D V ++ S + L PG EY+
Sbjct: 12635 DACSLSWHIPLED-GGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFR 12693
Query: 1428 IVALN--GREE---SPLLIGQ-QSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRIT 1481
+ A N G E SP ++ Q V P++ V + ++WD P
Sbjct: 12694 VRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRP---------- 12743
Query: 1482 YGETGGNSPVQEFTVPGSKSTATI----------------SGLKPGVDYTITVYAVTGRG 1525
++ G SP+ + + + + + +GL G++Y+ +YA+ G
Sbjct: 12744 --DSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAG 12801
Query: 1526 DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPKNG 1581
SP S + R +D P + +V DV +++S+ W S + GY V G
Sbjct: 12802 SSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPG 12861
Query: 1582 PGPTKTKTAGPD--QTEMTIEGLQPTVEYVVSVYAQN------PSGESQP---LVQTAVT 1630
+ TA Q E T GL+ +Y A+ PS S P L +
Sbjct: 12862 DKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPP 12921
Query: 1631 NIDRPKGL-------AFTDVDVDSIKIAWESPQGQVS-RYRVTYSSPEDGIHELFPAPDG 1682
ID + A T+V +D+ + P VS + T P +GI A
Sbjct: 12922 RIDLSVAMKSLLTVKAGTNVCLDA--TVFGKPMPTVSWKKDGTLLKPAEGIK---MAMQR 12976
Query: 1683 EEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQ 1741
T EL + ++ A + I + P P +K ++
Sbjct: 12977 NLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLS 13036
Query: 1742 WTPP----NVQLTGYRVRVTPKEKTGP-MKEINLAPDSSSVVVSGLMVATKYEVSV---- 1792
W PP ++T Y V +E + P +++ +S V L+ +Y+ +
Sbjct: 13037 WEPPLEDGGSEITNY--IVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAEN 13094
Query: 1793 -YALKDTLTSRPAQGVVTTLENVSPPRRAR---VTDATETTITISWRTKTE----TITGF 1844
Y + D + + PA PP R +++ T+ +T+SW+ + ITG+
Sbjct: 13095 KYGVGDPVFTEPA----IAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGY 13150
Query: 1845 QVDAVPANGQTPIQRTIKPDV-RSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI 1903
++ + KP + R+ TGLQ GT+Y+ + +N P DAS A
Sbjct: 13151 LLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKP--SDASKAA 13208
Query: 1904 DA---------PSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPR 1950
A P+ + TT +S+ +SW P + I GY+++ ++ S
Sbjct: 13209 YARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNL 13268
Query: 1951 PRP-GVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
P+ T +TGL T+Y V A+ S+P
Sbjct: 13269 PQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDP 13303
Score = 123 bits (309), Expect = 2e-27
Identities = 282/1358 (20%), Positives = 482/1358 (35%), Gaps = 200/1358 (14%)
Query: 780 LLPGRKYIVNVYQISEDGE----QSLILSTSQTTAPDAPPD-PTVDQVDDTSIVVRWSRP 834
L+ G +YI V ++ G+ QS + P PP+ P V V + V W RP
Sbjct: 14164 LIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRP 14223
Query: 835 Q----APITGYRIVYSPSVEGSSTE-LNLPETANSVTLSDLQPGVQYNITIYA-----VE 884
+ ITGY + + P + ++ LQ G Y + A +
Sbjct: 14224 VDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 14283
Query: 885 ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVD 940
E++ V+ ++ P + P D T ++ W P +TGY V+
Sbjct: 14284 PPSEASDSVLMKDAAYPPGPPSNPHVTD-----TTKKSASLAWGKPHYDGGLEITGYVVE 14338
Query: 941 VIPVN----LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ--QT 994
V + G L I++ V L Y F++ A++ +P +
Sbjct: 14339 HQKVGDEAWIKDTTGTALRITQFV---VPDLQTKEKYNFRISAINDAGVGEPAVIPDVEI 14395
Query: 995 TKLDAPTNLQFVNETDSTVLVR-------WTP----PRAQITGYRLTVGLTRRGQPRQYN 1043
+ + + + E T++VR + P P ++T + + L R
Sbjct: 14396 VEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTE 14455
Query: 1044 VGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI 1103
++ P N ++ +++ G + V T P ++ P T++T+ ++
Sbjct: 14456 -SFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRP--TDITKDSV 14512
Query: 1104 VITWT-PAPRIGFKLGVRPSQGGEAPREVTSDSGS------IVVSGLTPGVEYVYTIQVL 1156
+ W P G ++ + EA R+ S + + V+GL+ G EY + +
Sbjct: 14513 TLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAE 14572
Query: 1157 RD---GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITT 1210
+ G+ + K SPP +L++ + ++++W + ITGY I
Sbjct: 14573 NEYGIGEPTETTEPVKASEAPSPPDSLNI-MDITKSTVSLAWPKPKHDGGSKITGYVIEA 14631
Query: 1211 TPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTII----PA 1266
Q + V + C NL+ G EY V V S P +
Sbjct: 14632 QRKGSDQWTHITTVKGLE---CVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQT 14688
Query: 1267 VPPPTDLR-------FTNIGPDT---MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316
+ P DLR G + + V P P++ K + + + +
Sbjct: 14689 MLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTW----------KKGDQILKQTQ 14738
Query: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL-------------DSPTG 1363
+ + +L E V S S Y PL R G PTG
Sbjct: 14739 RVNFETTATSTILNINECVRSDSGPY------PLTARNIVGEVGDVITIQVHDIPGPPTG 14792
Query: 1364 -IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNL 1418
I F +++++ T W P I+ Y + S E R + T L
Sbjct: 14793 PIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTD-STTWVELATTVIRTTYKATRL 14851
Query: 1419 TPGTEYVVSIVALN------GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP- 1471
T G EY + A N G + ++ V P +V A T S+ ISW P
Sbjct: 14852 TTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPL 14911
Query: 1472 ---AVTVRYYRITYGETGGN--SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD 1526
+ Y + E G V + VPG+ + SGL G+ Y V A G
Sbjct: 14912 SDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKS--SGLTDGIAYEFRVIAENMAGK 14969
Query: 1527 SPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGP 1582
S S + ID P + ++ +++++KW +T Y V
Sbjct: 14970 SKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNG 15029
Query: 1583 GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ--TAVTNIDRPKGLAF 1640
K + + E T+ GL Y V A+N +G P + A+T D
Sbjct: 15030 RWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRD------- 15082
Query: 1641 TDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGL-------- 1692
DV+ IK+ + + + + D P + +D EL+G
Sbjct: 15083 -DVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIA 15141
Query: 1693 -------------RPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTD--LKFTQVTPTS 1737
R YT++ A + ++ + + P P + L T+VT
Sbjct: 15142 DFSTNLVNKDSTRRDSGAYTLT--ATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEK 15199
Query: 1738 LSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKY--- 1788
W PP ++ Y + K +T + N+A + + + V+ L+ +Y
Sbjct: 15200 CVLSWFPPLDDGGAKIDHY---IVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFR 15256
Query: 1789 --EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISW----RTKTETIT 1842
V+ Y + + L S P V PP+ VT T+ ++ + W I
Sbjct: 15257 VMAVNKYGVGEPLESEPVL-AVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEII 15315
Query: 1843 GFQVDAVPANGQTPIQRTIK--PDVRSYTITGLQPGTDYKIYLYTLNDNARSSP------ 1894
+ V+ GQ I+ K D+R Y ++GL G +Y+ + N S+P
Sbjct: 15316 NYIVERRDKAGQRWIKCNKKTLTDLR-YKVSGLTEGHEYEFRIMAENAAGISAPSPTSPF 15374
Query: 1895 -VVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVP 1949
D P N R L T+ +S+ ++W P + ITGY+++ P ++V
Sbjct: 15375 YKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVT 15434
Query: 1950 RPRP-GVTEATITGLEPGTEYTIYVIALKNNQKSEPLI 1986
P T TITGL EY I + A+ + EP +
Sbjct: 15435 PPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPAL 15472
Score = 121 bits (303), Expect = 9e-27
Identities = 287/1414 (20%), Positives = 508/1414 (35%), Gaps = 177/1414 (12%)
Query: 610 GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
GP E + T + WN P ++IS YI+ R + + W + + +Y
Sbjct: 18431 GPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLS-WTQVSTEVQALNY 18489
Query: 667 TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
+ L PG Y +++++ +YG E P+ S VT P ++
Sbjct: 18490 KVTKLLPGNEYIFRVMAVNKYGIGE-------------PLESGPVTACNPYKPPGPPSTP 18536
Query: 727 SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEP-----QYLDLPSTATSVNIPDLL 781
V+ IT S VV+W D G +E + E+ D+ + T + + L
Sbjct: 18537 EVSAITKDSMVVTWARPVDD-GGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLT 18595
Query: 782 PGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPP-DPTVDQVDDTSIVVRWSRP- 834
G Y N + E E S+ P PP +P V +S+ + WS+P
Sbjct: 18596 EGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPI 18655
Query: 835 ---QAPITGYRIVYSPSVEGSSTELNLPE--TANSVTLSDLQPGVQYNITIYAVEENQES 889
AP+ GY + + T P T++ L+ +YN I A+
Sbjct: 18656 YDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVG 18715
Query: 890 TPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK--------VTIMWTP-PE---SAVTGY 937
P + R + D +V ++ VTI P PE G
Sbjct: 18716 EPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGI 18775
Query: 938 RVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL 997
D + + + VT G Y + G ++ + +
Sbjct: 18776 LTDRAQIEVTSS------FTMLVIDNVTRFDSG--RYNLTLENNSGSKTAFVNVRVLDSP 18827
Query: 998 DAPTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPL 1053
AP NL +V + W PP A+IT Y + T R + + + +
Sbjct: 18828 SAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRI 18887
Query: 1054 RNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN------TEVTETTIVITW 1107
NLQ Y ++A + E TT S PP +VT T I W
Sbjct: 18888 ENLQEGCSYYFRVLA---SNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKW 18944
Query: 1108 T-PAPRIGFKLG----VRPSQGGEAPREVTS-DSGSIVVSGLTPGVEYVYTIQVLR---- 1157
P G K+ ++G E T + +SGLT G EYV+ + +
Sbjct: 18945 EKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGR 19004
Query: 1158 -DGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGY-RITTTPTNG 1215
D ++ P++ + + + P L V D+ R T
Sbjct: 19005 SDPRQLGVPVIARDIE-IKPSVELPFHT------FNVKAREQLKIDVPFKGRPQATVNWR 19057
Query: 1216 QQGNSLEEVVHADQSSC---TFDNLSPGLEYNVSVYTVKDDKES----VPISDTIIPAVP 1268
+ G +L+E + SS T ++ + +V Y + + VPI+ ++
Sbjct: 19058 KDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPG 19117
Query: 1269 PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAE---LSISPSDNA 1322
PP +R + D++ ++W PP ++N++V K E +S + + +
Sbjct: 19118 PPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVE----KKETTSTTWHIVSQAVARTS 19173
Query: 1323 VVLTNLLPGTEYVVSVSS-----VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTV 1376
+ + L G+EY V + ES+ + P G T ++ V
Sbjct: 19174 IKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLV 19233
Query: 1377 HWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN 1432
W P + + GY + + + +++ + + ++ L G Y + A N
Sbjct: 19234 TWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAEN 19293
Query: 1433 ----GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGE 1484
G+ D P EV T S+ + W P + Y + E
Sbjct: 19294 IAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRE 19353
Query: 1485 TGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEID 1543
++ ++ ++ L Y V+A S S I + +++
Sbjct: 19354 LPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVE 19413
Query: 1544 KPSQMQVTDVQDNSI--SVKWLPSSSPVTG--YRVTTTPKNG---PGPTKTKTAGPD-QT 1595
P M +D + + + L ++ + G V + K+G +T+ D T
Sbjct: 19414 PPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHT 19473
Query: 1596 EMTIEGL--QPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKG--LAFTDVDVDSIKIA 1651
+T++ + T +YV+++ +N +G V V + P L + + ++
Sbjct: 19474 LLTVKDCIRRDTGQYVLTL--KNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLS 19531
Query: 1652 WESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGE--EDTAELQGLRPGSEYTVSVVAL 1705
W PQ + Y V + H + +GE + ++ L G+EY V +
Sbjct: 19532 WGRPQEDGGADIDYYIV---EKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGV 19588
Query: 1706 HDDMESQPLIGTQSTAIPA---------PTDLKFTQVTPTSLSAQWTPP----NVQLTGY 1752
+ +PL +S AI A PT L+ T VT S++ W+ P +++GY
Sbjct: 19589 NKYGVGEPL---ESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGY 19645
Query: 1753 RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTT 1810
+ K ++ V +GL +YE VYA S P++ ++
Sbjct: 19646 IIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRA 19705
Query: 1811 LENV---SPPRRARVTDATETTITISWRTKT----ETITGFQVD---AVPANGQTPIQRT 1860
+ V SPP + ++ D+ +TTITI+W ITG+ V+ + + +T IQ
Sbjct: 19706 EDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSL 19765
Query: 1861 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP 1894
+ YTI+GL G +Y + ++N S P
Sbjct: 19766 RGTE---YTISGLTTGAEYVFRVKSVNKVGASDP 19796
Score = 120 bits (302), Expect = 1e-26
Identities = 326/1553 (20%), Positives = 547/1553 (35%), Gaps = 248/1553 (15%)
Query: 605 YPSSSGPVEVFITETPSQPNSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEA-TIP 660
Y P+ V IT+ S + W P+ + I+ Y++ R K S+ RW A T+
Sbjct: 6816 YDVPGPPLNVTITDVNRFGVS--LTWEPPEYDGGAEITNYVIELRDKTSI-RWDTAMTVR 6872
Query: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
S T+ V EGQ S + R S +TP E P P
Sbjct: 6873 AEDLSATVTD-----VVEGQEYSFRVRAQN---RIGVGKPSAATPFVKVADPIER-PSPP 6923
Query: 721 LVATSESVTEITASSFVVSWV----SASDTVSGFRVEYELSEEGDEPQY---LDLPSTAT 773
+ TS T+ SS + W + G+ +E EEG + + L T
Sbjct: 6924 VNLTSSDQTQ---SSVQLKWEPPLKDGGSPILGYIIER--CEEGKDNWIRCNMKLVPELT 6978
Query: 774 SVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV---DDTSIVVR 830
+ L G KY+ V ++ G TA DA +PT+D D ++V
Sbjct: 6979 -YKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIV- 7036
Query: 831 WSRP---QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSD-----LQPGVQYNITIYA 882
P P TGY + G L + TLS + P + + IY
Sbjct: 7037 -PNPITILVPSTGYPRPTATWCFGDKV-LETGDRVKMKTLSAYAELVISPSERSDKGIYT 7094
Query: 883 VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYR 938
++ + + + R +P++L+F ++T V + W PP+ S +TGY
Sbjct: 7095 LKLENRVKTISGEIDVNVIARPS---APKELKFGDITKDSVHLTWEPPDDDGGSPLTGYV 7151
Query: 939 VDVIPVNLPGEHGQRLPISRNTFAE-----------VTGLSPGVTYYFKVFAVSHGRESK 987
V ++ +SR T+ + V L G Y FKV A + +
Sbjct: 7152 V------------EKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGE 7199
Query: 988 PLTAQQTTKL-------DAPTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRR 1036
P + + D P N+++ + T +++ + W PP+ ++I GY V R
Sbjct: 7200 PAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGY--IVERCPR 7257
Query: 1037 GQPRQYNVGPSV--SKYPLRNLQPASEYTVSLVAIK-----------------GNQESPK 1077
G + G V +K + L+ Y + A+ QE+P+
Sbjct: 7258 GSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPE 7317
Query: 1078 ATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGF-KLGVRPSQGGEAPREVTSDSG 1136
+F ++ + + E +T P P+I + K + Q E
Sbjct: 7318 ---IFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKS 7374
Query: 1137 SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHL-EANPDTGVLTVSW 1195
++ + Y I+ + A + V+ PP + + ++ +LT +
Sbjct: 7375 TVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNP 7434
Query: 1196 ERST-TPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV-----YT 1249
R IT Y + T+ + + L V T L P EY V Y
Sbjct: 7435 PRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKAT--KLIPNKEYIFRVAAENMYG 7492
Query: 1250 VKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPV 1305
V + ++ PI+ P PPT L ++I D + +TW P +T + V
Sbjct: 7493 VGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDP 7552
Query: 1306 KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGID 1365
++ V + D + L +Y V + P + + + P
Sbjct: 7553 DTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPP 7612
Query: 1366 F-------SDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPR-EDRVPHSRNSI 1413
+ D+ S ++W P A I Y I R + VP +++
Sbjct: 7613 WPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH-- 7670
Query: 1414 TLTNLTPGTEYVVSIVALNGREES-------PLLIGQQSTVSDVPRDLEVVAATPTSLLI 1466
L L G EY + A+N ES P+L ++ PR LEV+ T + +
Sbjct: 7671 LLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADL 7730
Query: 1467 SWDAPAVTVRYYRITYGETGGNSPVQEFTVPG---------------SKSTATISGLKPG 1511
W P E G SP+ + V + T++ L G
Sbjct: 7731 KWTVP------------EKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEG 7778
Query: 1512 VDYTITVYAVTGRGDSPASSKPISINYR---TEIDKPSQMQVTDVQDNSISVKWLPSSS- 1567
Y V A G S + S+ + T P + V DV + +KW P +
Sbjct: 7779 SLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKND 7838
Query: 1568 ---PVTGYRVTTTPKNGPGPTKT-KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
P+ Y + + G K KTAGPD + ++ T E V A+N +G P
Sbjct: 7839 GGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGT-EVQFQVRAENEAGVGHP 7897
Query: 1624 LVQTAVTNIDRPKG-------LAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHEL 1676
T + +I+ P L TD I IAW+ P+ SP G H +
Sbjct: 7898 SEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPE-------KNGGSPIIGYH-V 7949
Query: 1677 FPAPDGEEDTAEL-------------QGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP 1723
P G E + +G+ P EY + V A++ S+P +++
Sbjct: 7950 EMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAK 8009
Query: 1724 APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLM 1783
P D K T T + + G ++ + + P+ ++ D V S +
Sbjct: 8010 DP-DCKPTIDLETH-------DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRL 8061
Query: 1784 VATKYEVSVYALKDTLTSRPAQGVVT-TLEN----------------VSPPRRARVTDAT 1826
+S + L+ + R G+ T TLEN P + + +D T
Sbjct: 8062 TMKNDHISAH-LEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDIT 8120
Query: 1827 ETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIY 1882
+++ ++W I + ++ A +T I + S+T+ L P +Y
Sbjct: 8121 KSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFR 8180
Query: 1883 LYTLND-------NARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARIT 1931
+ +N ++ + D D P ++ T ++ ++W+PP ++I
Sbjct: 8181 VKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIM 8240
Query: 1932 GYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
GYII+ G + + T GLE G EY V A SEP
Sbjct: 8241 GYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEP 8293
Score = 118 bits (296), Expect = 6e-26
Identities = 316/1543 (20%), Positives = 554/1543 (35%), Gaps = 238/1543 (15%)
Query: 607 SSSGPVEVFIT----ETPSQPNSHPIQWNAPQPSHISKYILRWRP---------KNSVGR 653
+SSG F+T +TP P + ++ + L W P KN V
Sbjct: 17727 NSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSA-----FLVWEPPIIDGGAKVKNYVID 17781
Query: 654 WKEATIPGHLN--------SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTP 705
+E+T + N S+ ++ L G +Y ++++ ++G P
Sbjct: 17782 KRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG-------------VGVP 17828
Query: 706 VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGD 761
V + P SP ++T+++ +S + W V G+ VE + +G
Sbjct: 17829 VETVDAVKAAEPPSP--PGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE--MQPKGT 17884
Query: 762 EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQ 821
E + S + + L G++Y V +E G+ + A D P++
Sbjct: 17885 EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKL 17944
Query: 822 VDDTSIVVRWS--RPQAPITGY-RIVYSPSVEGS----STELNLPETANSVTLSDLQPGV 874
+T + + + P+ G R S +G +T +N+ ETA S L ++ G
Sbjct: 17945 PFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLH-IKEGN 18003
Query: 875 QYNITIYAVEENQESTPV-----VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTP 929
+ + Y V + VI E G P ++F EV+ V I W P
Sbjct: 18004 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGP-------VRFDEVSADFVVISWEP 18056
Query: 930 PESA----VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE 985
P ++ Y V+ H ++R T ++T L G Y F++FA + +
Sbjct: 18057 PAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTI-KITKLKTGTEYQFRIFAENRYGK 18115
Query: 986 SKPLTA-----QQTTKLDAPTNLQFVNE-TDSTVLVRWTPP----RAQITGYRLTVGLTR 1035
S PL + Q K P FV + +LV+W P +I GY L
Sbjct: 18116 SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 18175
Query: 1036 RGQPRQYNVGP-SVSKYPLRNLQPASEYT--VSLVAIKGNQESPKATGVFTTLQPGSSIP 1092
+ N P +K+ L EY VS I G + K + F P P
Sbjct: 18176 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCD--P 18233
Query: 1093 PYNTE---VTETTIVITWT-PAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
P E +T + + W PA G K+ + + P G + + T +E
Sbjct: 18234 PGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLP------DGRWMKASFTNVLE 18287
Query: 1149 YVYTIQVLRDGQERDAPIVNK-VVTPLSPPT---------------NLHLEANPDTGVLT 1192
+T+ L + Q + ++ + S P+ N L+ ++
Sbjct: 18288 TEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVV 18347
Query: 1193 VSWERSTTP-DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLS---------PGLE 1242
+ E DI G I + + G LEE + T + G +
Sbjct: 18348 HAGETFVLEADIRGKPIPDVVWS-KDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18406
Query: 1243 YNVSVYTVKDDKESVPISDTIIPAVPPPTD-LRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301
Y + + V K S+PI+ ++ PP L+ T + + + W PP N
Sbjct: 18407 YILKLSNVGGTK-SIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHY 18465
Query: 1302 YSPVKNEEDVAELSISPSDNAV--VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1359
+ ++ +S A+ +T LLPG EY+ V +V + PL T +
Sbjct: 18466 IIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACN 18525
Query: 1360 S------PTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHS 1409
P+ + S IT +S V W P I GY + + + ++ +
Sbjct: 18526 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 18585
Query: 1410 RNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTV---SDVPRDLEVVAATPT 1462
+ +T LT G Y + A N G P + + P + +V + +
Sbjct: 18586 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRS 18645
Query: 1463 SLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-----------------TI 1505
S+ ++W P G +PV+ + V ++ A T+
Sbjct: 18646 SVSLAWSKPIYD------------GGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTV 18693
Query: 1506 SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPS 1565
+ LK +Y + A+ G ++ P S+ + I+ P D++ V L +
Sbjct: 18694 TKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLR----KVVVLRA 18749
Query: 1566 SSPVTGYRVTTTPKNGPGPT----KTKTAGPD--QTEMTIEGLQPTVEYVV-------SV 1612
S+ + R+ T K P P K + D Q E+T ++ V ++
Sbjct: 18750 SATL---RLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNL 18806
Query: 1613 YAQNPSGESQPLVQTAVTNI-DRPKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYS 1667
+N SG V V + P L +V DS+ ++WE P +++ Y V
Sbjct: 18807 TLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKR 18866
Query: 1668 SPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT- 1726
+ + + T ++ L+ G Y V+A ++ P T+ + P
Sbjct: 18867 ETTRKAYATI-TNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPL 18925
Query: 1727 ---DLKFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPK--EKTGPMKEINLAPDSSSV 1777
+ VT + + +W P ++TGY V + K EK ++ +
Sbjct: 18926 PPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVK----TLEA 18981
Query: 1778 VVSGLMVATKYEVSVYALKDTLTSRPAQ-GVVTTLENVS-------PPRRARVTDATETT 1829
+SGL +Y V A+ + S P Q GV ++ P V +
Sbjct: 18982 TISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLK 19041
Query: 1830 ITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ----PGTDYKIYLYT 1885
I + ++ + + ++ D GQT + T S T+T L D Y
Sbjct: 19042 IDVPFKGRPQATVNWRKD-----GQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELC 19096
Query: 1886 LNDNARSS--PVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEK 1939
++++A S P+ I P +R + +S+ +SW PP +I+ YI++ ++
Sbjct: 19097 VSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKE 19156
Query: 1940 PGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 1982
S +V + T I L G+EY V A KS
Sbjct: 19157 TTSTTWHIVSQ-AVARTSIKIVRLTTGSEYQFRVCAENRYGKS 19198
Score = 118 bits (295), Expect = 8e-26
Identities = 287/1359 (21%), Positives = 491/1359 (36%), Gaps = 205/1359 (15%)
Query: 780 LLPGRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP 834
++ G +YI VN Y I E E +++ + P P P V ++ S+ V WSRP
Sbjct: 20658 IIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRP 20717
Query: 835 QA----PITGYRIVYSPSVEGSSTEL---NLPETANSVTLSDLQPGVQYNI-TIYAVEEN 886
A I+GY + ++ + +T VT QY + + A +
Sbjct: 20718 IADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQG 20777
Query: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVI 942
S P + D P ++ + T +T+ W+ P SAVTGY V++
Sbjct: 20778 PFSEP---SEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEI- 20833
Query: 943 PVNLPGEHGQRLPIS-----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK- 996
GE + +S R T V+ L PGV YYF+V AV+ + +P+ + +
Sbjct: 20834 ---RQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQA 20890
Query: 997 ---LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--------RQYNVG 1045
L+AP E D V +R T A+ G + V + +G+P + N+G
Sbjct: 20891 KDILEAP-------EIDLDVALR-TSVIAK-AGEDVQVLIPFKGRPPPTVTWRKDEKNLG 20941
Query: 1046 PSVSKYPLRNLQPASEYTVS----------LVAIKGNQESPKATGVFTTL--QPGSSIPP 1093
S ++Y + N +S T+ ++ I+ PK++ V + P +
Sbjct: 20942 -SDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKL 21000
Query: 1094 YNTEVTETTIVITWTP------APRIGFKLGVRPS---QGGEAPREVTSDSGSIV-VSGL 1143
V+ T+ + W P +P I + + R + + +S S ++ +S
Sbjct: 21001 QVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEK 21060
Query: 1144 TPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDI 1203
TP V + G+ + K +P +L ++ + T V+ +SW T PD
Sbjct: 21061 TPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVI-LSW---TKPDF 21116
Query: 1204 TGYRITTTPTNGQQGNSLEEVVHADQS-SCTFD----NLSPGLEYNVSVYTVKDDKESVP 1258
G + T ++G + HA S +C + LE+ V K + V
Sbjct: 21117 DGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVT 21176
Query: 1259 ISDTIIP--AVPPPTDLRFTNIGPDTMRV----------TWAPPPSIDLTNFLVRYSPVK 1306
I + + P DL T+R+ P PSI ++L P+K
Sbjct: 21177 IGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSI---SWLKDGLPLK 21233
Query: 1307 NEEDVAELSISPSDNAVVLT----NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1362
E V S ++N + L+ G +Y V + + + P+ P
Sbjct: 21234 ESEFV---RFSKTENKITLSIKNAKKEHGGKYTVILDNAV-CRIAVPITVITLGPPSKPK 21289
Query: 1363 G-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
G I F +I A+S + W P IT Y I E + +R + + N
Sbjct: 21290 GPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKR-ETSQTNWKMVCSSVARTTFKVPN 21348
Query: 1418 LTPGTEYVVSIVALNGREESPLLIG------QQSTVSDVPRDLEVVAATPTSLLISWDAP 1471
L EY + A N S L+ Q + P + T + ++WDAP
Sbjct: 21349 LVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAP 21408
Query: 1472 AV----TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
V + + E + T P S +GL G+DY VYA G S
Sbjct: 21409 VYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLS 21468
Query: 1528 PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPG 1583
S + +D P DV +I++KW P S + GY + N
Sbjct: 21469 SPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERW 21528
Query: 1584 PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN------PSGESQPLVQTAVTNIDRPKG 1637
+ + + T+ GL P Y + A+N P +S ++ T N+ P
Sbjct: 21529 -VRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENV--PPI 21585
Query: 1638 LAFTDVDVDSI--------------------KIAWESPQGQVSRYRVTYSSPEDGIHELF 1677
+ F D + ++ W ++ + + G LF
Sbjct: 21586 VEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLF 21645
Query: 1678 PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTS 1737
+ T + +G+ YTV +++ + Q T ++FT +T
Sbjct: 21646 V----RDATRDHRGV-----YTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEK 21696
Query: 1738 LSAQWTPP-NVQLTGYRVRVTPKEKTGPM--KEINLAPDSSSVVVSGLMVATKYEVSVYA 1794
++ W P N + K +T + I ++ S L+ +Y+ V A
Sbjct: 21697 MTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSA 21756
Query: 1795 LKDTLTSRP--AQGVVTTLENVSP--PRRARVTDATETTITISWRTKTETITGFQVDA-- 1848
+ RP + VV ++ P P ++ T +IT++W + E+ G ++
Sbjct: 21757 VNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTW-ARPESDGGSEIQQYI 21815
Query: 1849 -----------VPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1897
V + PI T + +TGL G +Y+ ++ + +NA
Sbjct: 21816 LERREKKSTRWVKVISKRPISET------RFKVTGLTEGNEYEFHV--MAENAAGVGPAS 21867
Query: 1898 DASTAIDA---------PSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPP 1944
S I P+ ++ T+ ++ + W P I GYII+ K
Sbjct: 21868 GISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGD 21927
Query: 1945 REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 1983
V T T+T L+ G EY V A+ K +
Sbjct: 21928 WHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGD 21966
Score = 117 bits (293), Expect = 1e-25
Identities = 324/1541 (21%), Positives = 541/1541 (35%), Gaps = 222/1541 (14%)
Query: 612 VEVFITETPSQPNSHPIQ----------WNAPQP---SHISKYILRWRPKNSVGRWKEAT 658
VEV + + P P + I WN P+ S I+ Y++ R +S W + +
Sbjct: 7404 VEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEV-WHKLS 7462
Query: 659 IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
++ L P Y ++ + YG E PV ++ +T +
Sbjct: 7463 STVKDTNFKATKLIPNKEYIFRVAAENMYGVGE-------------PVQASPITAKYQFD 7509
Query: 719 SPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATS 774
P T ++IT + ++W D ++G+ VE + + +P T+
Sbjct: 7510 PPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTT 7569
Query: 775 VNIPDLLPGRKYIVNVY--QISEDGEQSL----ILSTSQTTAPDAPPDPTVDQVDDTSIV 828
+ L +KY V ++ G+ S IL P P PTV V TS+
Sbjct: 7570 YRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVR 7629
Query: 829 VRWSRPQ----APITGY--RIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA 882
+ W++P+ A I Y ++ + + E +P T + L L G +Y+ + A
Sbjct: 7630 LNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH--LLPGLMEGQEYSFRVRA 7687
Query: 883 VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYR 938
V + ES P + PR L+ + +T + WT PE S +T Y
Sbjct: 7688 VNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYI 7747
Query: 939 VDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH-GR------ESKPLTA 991
V+ V G + ++T VT L+ G Y F+V A + G+ E L
Sbjct: 7748 VEKRDVRRKGWQTVDTTV-KDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAK 7806
Query: 992 QQTTKLDAPTNLQFVNETDSTVLVRWTPPR--AQITGYRLTVGLTRRGQPRQYNVGPSVS 1049
T P L V+ T V ++W PP+ R + R R G +
Sbjct: 7807 DTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAG 7866
Query: 1050 KYPLRNLQPASEYTVSLVAIKGNQES-----PKATGVFTTLQPGS-SIPPYNTEVTET-- 1101
+ E T ++ E+ + T + + P S PP + VT+
Sbjct: 7867 PDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGR 7926
Query: 1102 -TIVITWTP------APRIGFKLGVRPSQGGEAPREVTS----DSGSIVVSGLTPGVEYV 1150
I I W P +P IG+ + + P G E V S D V G+ P EYV
Sbjct: 7927 KHIAIAWKPPEKNGGSPIIGYHVEMCP-VGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYV 7985
Query: 1151 YTIQVLRD-GQERDAPIVNKVVT--PLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYR 1207
++ + G + I VV P PT + LE + ++ + E+ + P +R
Sbjct: 7986 LRVRAVNAIGVSEPSEISENVVAKDPDCKPT-IDLETH---DIIVIEGEKLSIP--VPFR 8039
Query: 1208 ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY------NVSVYTV----KDDKESV 1257
PT + +EV +D+ + D++S LE + +YT+ K +
Sbjct: 8040 AVPVPTVSWHKDG-KEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATA 8098
Query: 1258 PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSIS 1317
I+ +I P D++ ++I + ++TW PP T L + + +
Sbjct: 8099 SINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVM 8158
Query: 1318 PSDNAVVLT--NLLPGTEYVVSVSSV-------YEQHESTPLRGRQKTGLDSPTGIDFSD 1368
+N + T +L+P EY V +V Y + ++ + K D P ++ +
Sbjct: 8159 SGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHN 8218
Query: 1369 ITANSFTVHWIAP----RATITGYRIRH--HPEHFSGRPREDRVPHSRNSITLTNLTPGT 1422
TA + T+ W P + I GY I E R E VP + T L G
Sbjct: 8219 PTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPIL--TYTAKGLEEGK 8276
Query: 1423 EYVVSIVALNGREESPLLIGQQSTVSDVPRDL-EVVAATPTSLL----ISWDAPAVTVRY 1477
EY + A N S T + P D +V+ T + I+ DA Y
Sbjct: 8277 EYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPY 8336
Query: 1478 YRITY------------------------GETGGNSP-----VQEFTVPGSKSTATISGL 1508
IT+ GE P Q ++ SK + +
Sbjct: 8337 PTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRV 8396
Query: 1509 KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP---- 1564
+ + +Y + D + P +++ P D++ S+ KW P
Sbjct: 8397 RDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDD 8456
Query: 1565 SSSPVTGYRVTTTPKNGP-GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
S + Y + K P T+ + ++ L EY+ V A+N G P
Sbjct: 8457 GGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPP 8516
Query: 1624 LVQTAVT------NIDRPKGLAFTDVDVDSIKIAWESPQ-------GQVSRYRVTYSSPE 1670
V + D P DV +S+ + W P+ G R S+
Sbjct: 8517 CVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHW 8576
Query: 1671 DGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD------DMESQPLIGTQSTAIPA 1724
+++ A + GL G Y V A + S P + P
Sbjct: 8577 SRVNKSLL----NALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPG 8632
Query: 1725 PTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV--- 1777
P + T + T++ +W PP ++ GY V K+ G + V
Sbjct: 8633 PPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFV---DKQLVGTNEWSRCTEKMIKVRQY 8689
Query: 1778 VVSGLMVATKYEVSVYALKDTLTSRPAQ-GVVTTLENVSPPRRARVTDATETTITISWRT 1836
V + Y++ V A+ P + VT E PP A E +++
Sbjct: 8690 TVKEIREGADYKLRVSAVNAAGEGPPGETQPVTVAEPQEPP-------AVELDVSVKGGI 8742
Query: 1837 KTETITGFQVDAVPANGQTPIQRTIKPD--------------VRSYTITGLQPGTDYKIY 1882
+ ++ AV P + K + +S I D+ Y
Sbjct: 8743 QIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRY 8802
Query: 1883 LYTLNDNARSSPVVIDASTAIDAPS---NLRFLATTPNSLLVSWQPPR----ARITGYII 1935
+ T N+ S D P +L+ + T L++W P + ITG+II
Sbjct: 8803 VITAT-NSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFII 8861
Query: 1936 KYEKPGSPP-REVVPRPRPGVTEATITGLEPGTEYTIYVIA 1975
+ + R+ + R ++ ITGL G EY VIA
Sbjct: 8862 ERKDAKMHTWRQPIETER---SKCDITGLLEGQEYKFRVIA 8899
Score = 117 bits (293), Expect = 1e-25
Identities = 292/1326 (22%), Positives = 488/1326 (36%), Gaps = 202/1326 (15%)
Query: 811 PDAPPDPT-VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSV 865
P P P + V + + W P+ + IT Y I + + ++ +
Sbjct: 9845 PGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTY 9904
Query: 866 TLSDLQPGVQYNITIYAVEENQESTPVVIQQETT-------GTPRSDTVPSPRDLQFVEV 918
T+ L G +Y I A + P+ + ET G P TV S V
Sbjct: 9905 TIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSS--------V 9956
Query: 919 TDVKVTIMWTPPE----SAVTGYRVDVIPVNLPG-EHGQRLPISRNTFA---EVTGLSPG 970
T +T+ W PE S VTGY +++ + R PI T +VTGL G
Sbjct: 9957 TRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEG 10016
Query: 971 VTYYFKVFAVSHGR------ESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR--- 1021
Y F+V+A++ S P TA+ P + + T S+ + W+PP
Sbjct: 10017 SDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDG 10076
Query: 1022 -AQITGYRLTVGLTRRGQPRQYNVGPSV----SKYPLRNLQPASEYT--VSLVAIKGNQE 1074
+++TGY V G+ ++ G +K + L+ + Y V V I G E
Sbjct: 10077 GSKVTGY--IVEYKEEGK-EEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGE 10133
Query: 1075 SPKATGVFTT--------LQPGSSIPP----YNTEVTETTIVITWTPAPRIGFKLGVRPS 1122
+ T V LQ +S+ + V ++ P P + + + R +
Sbjct: 10134 PGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNER-T 10192
Query: 1123 QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT---PLSPPTN 1179
EA E T+ S S+V+ + VY++ + ER I+ V+ P+ P
Sbjct: 10193 LPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFL 10252
Query: 1180 LHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239
H N + S E IT Y I ++ + + V + + T L
Sbjct: 10253 AHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTV--TRQNATVQGLIQ 10310
Query: 1240 GLEY--------NVSVYTVKDDKESVPISDTIIPAVPP-PTDLRFTNIGPDTMRVTWAPP 1290
G Y ++ + + E++ I + I VP P DL + +T+ +TW PP
Sbjct: 10311 GKAYFFRIAAENSIGMGPFVETSEALVIREPI--TVPERPEDLEVKEVTKNTVTLTWNPP 10368
Query: 1291 P---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHES 1347
++ N+++ + E+ + + + L G Y VS+V +
Sbjct: 10369 KYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQG 10428
Query: 1348 TPLRGRQ----KTGLDSPT-GIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPR 1402
P + K L PT +DF D T+ + +TG +SG+P+
Sbjct: 10429 KPSFCTKPITCKDELAPPTLHLDFRD----KLTIR-VGEAFALTG--------RYSGKPK 10475
Query: 1403 ------EDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQST--------VS 1448
+D + T TP T + I A ++ + ST V+
Sbjct: 10476 PKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVN 10535
Query: 1449 DVPRDLEVVA------ATPTSLLISWDAP----AVTVRYYRITYGETGGN--SPVQEFTV 1496
V R V T ++ISW P + Y I E G + PV T
Sbjct: 10536 VVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPV---TS 10592
Query: 1497 PGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEI-DKPSQMQVTDVQ 1554
+K+T +S L G DY ++A G S P S + R + D P Q VT+V
Sbjct: 10593 ASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVT 10652
Query: 1555 DNSISVKWLP---SSSPVTGY---RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEY 1608
+S V W P+T Y + T K TK T+ + L +Y
Sbjct: 10653 KDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIH--PYTKFRVPDLLEGCQY 10710
Query: 1609 VVSVYAQN------PSGESQPL-VQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQ----G 1657
V A+N PS S+P+ + + P D +S+ + W+ P+
Sbjct: 10711 EFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGS 10770
Query: 1658 QVSRYRVTYSSPEDGI-HELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLI 1715
++ Y V Y D P+ +T ++ GLR G Y V+A++ ES P
Sbjct: 10771 KILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDP-- 10828
Query: 1716 GTQSTAIPAPTDLKFTQVTP-TSLSAQWTPPNVQLTGYRVRVT------PKEKTGPMKEI 1768
+P P +K P L A G +R++ P K KE
Sbjct: 10829 ----AHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKED 10884
Query: 1769 NLAPDSSSVVVSGLMVATKYEV--------SVYAL--KDTLTSRPAQGVVTTLENVSPPR 1818
AP + + V+ V +K E+ +Y+L ++ S+ V L+ PPR
Sbjct: 10885 RDAPTKARIDVT--PVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPR 10942
Query: 1819 RARVTDATETTITISWRTKTE----TITGFQVDA--VPANGQTPIQRTIKPDVRSYTITG 1872
V++ + + ++W+ + IT + V+ V + +P+ T K +S+
Sbjct: 10943 DLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKK--KSHFAKH 11000
Query: 1873 LQPGTDYKIYLYTLNDNARSSPV-------VIDASTAIDAPSNLRFLATTPNSLLVSWQP 1925
L G Y + N R V +D P +L + + + W
Sbjct: 11001 LNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNK 11060
Query: 1926 P----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 1981
P + ITGY+++Y++ G+ ++ + E +TGL+ G Y V K
Sbjct: 11061 PDRDGGSPITGYLVEYQEEGT--QDWIKFKTVTNLECVVTGLQQGKTYRFRV-------K 11111
Query: 1982 SEPLIG 1987
+E ++G
Sbjct: 11112 AENIVG 11117
Score = 112 bits (281), Expect = 3e-24
Identities = 265/1361 (19%), Positives = 500/1361 (36%), Gaps = 176/1361 (12%)
Query: 766 LDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT 825
+D + TS I + G K + ++ G+ ++ P + V + D
Sbjct: 6673 IDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDG 6732
Query: 826 SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPG-VQYNIT 879
+ + W P + I GY +V ++ + L + T++ LQ G V+Y
Sbjct: 6733 EVSLAWEEPLTDGGSKIIGY-VVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFR 6791
Query: 880 IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVT 935
+ A PV + D P ++ +V V++ W PPE + +T
Sbjct: 6792 VSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEIT 6851
Query: 936 GYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT 995
Y +++ + + A VT + G Y F+V A + KP A
Sbjct: 6852 NYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFV 6911
Query: 996 KL-------DAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR---- 1040
K+ P NL ++T S+V ++W PP + I GY + G+
Sbjct: 6912 KVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGY--IIERCEEGKDNWIRC 6969
Query: 1041 QYNVGPSVSKYPLRNLQPASE--YTVSLVAIKGNQESPKATGVFTT----LQPGSSIPPY 1094
+ P ++ Y + L+ ++ Y VS G + + G T ++P + +
Sbjct: 6970 NMKLVPELT-YKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAF 7028
Query: 1095 NTEV-----TETTIVI--TWTPAPRIGFKLGVRPSQGGEAPREVT-SDSGSIVVSGLTPG 1146
+ TI++ T P P + G + + G+ + T S +V+S
Sbjct: 7029 KDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERS 7088
Query: 1147 VEYVYTIQVLRDGQERDAPI-VNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD--- 1202
+ +YT+++ + I VN + P +P + D+ LT WE PD
Sbjct: 7089 DKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLT--WE---PPDDDG 7143
Query: 1203 ---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY--NVSVYTVKDDKESV 1257
+TGY + + + + + V T +L G EY V E
Sbjct: 7144 GSPLTGYVVEKREVSRKTWTKVMDFV--TDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7201
Query: 1258 PISDTIIPAVP-----PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEE 1309
+ + + + P PP ++++ + +++ +TW PP + + ++V P +++
Sbjct: 7202 YVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDK 7261
Query: 1310 DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDI 1369
VA ++ + +T L G Y V ++ Q S P R ++ +D +
Sbjct: 7262 WVA-CGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEI-----QAVDTQEA 7315
Query: 1370 TANSFTVHWIAPRATITGYRIRHHPEHFSGRP-------REDRVPHSRNSITLTNLTPGT 1422
V +A G +I P +G+P + D + IT+ N+
Sbjct: 7316 PEIFLDVKLLAGLTVKAGTKI-ELPATVTGKPEPKITWTKADMILKQDKRITIENVP--K 7372
Query: 1423 EYVVSIVALNGREESPLLI------GQQSTVSDV--------PRDLEVVAATPTSLLISW 1468
+ V+IV + +I G+ + V +V P ++ T S L++W
Sbjct: 7373 KSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTW 7432
Query: 1469 DAP----AVTVRYYRITYGETGG------NSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
+ P + Y + T +S V++ +K L P +Y V
Sbjct: 7433 NPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATK-------LIPNKEYIFRV 7485
Query: 1519 YAVTGRG-DSPASSKPISINYRTE-IDKPSQMQVTDVQDNSISVKWL----PSSSPVTGY 1572
A G P + PI+ Y+ + P++++ +D+ +++++ W SP+TGY
Sbjct: 7486 AAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGY 7545
Query: 1573 RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LV 1625
V + + T ++GL +Y V A+N +G +P L+
Sbjct: 7546 WVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILI 7605
Query: 1626 QTAVTNIDRPKGLAFTDVDVDSIKIAWESPQ--GQVSRYRVTYSSPEDGIHELFPAPDGE 1683
+ + P DV S+++ W P+ G + G E +G
Sbjct: 7606 KDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGV 7665
Query: 1684 EDTAE-LQGLRPGSEYTVSVVALHDDMESQ------PLIGTQSTAIPAPTD-LKFTQVTP 1735
T L GL G EY+ V A++ ES+ P++ + P+P L+ +T
Sbjct: 7666 PTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITK 7725
Query: 1736 TSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS 1791
+ +WT P +T Y V + G + ++ + V+ L E S
Sbjct: 7726 NTADLKWTVPEKDGGSPITNYIVEKRDVRRKG-WQTVDTTVKDTKCTVTPLT-----EGS 7779
Query: 1792 VYALKDTLTSRPAQGVVTTLEN----------VSPPRRARVTDATETTITISWRTKT--- 1838
+Y + + Q T +E+ PP V D T+ + + W
Sbjct: 7780 LYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDG 7839
Query: 1839 -ETITGFQVDAVPANGQTPIQ--RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP- 1894
I + ++ G ++ +T PD ++ +T + GT+ + + N+ P
Sbjct: 7840 GRPIQRYVIEKKERLGTRWVKAGKTAGPDC-NFRVTDVIEGTEVQFQVRAENEAGVGHPS 7898
Query: 1895 ------VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPP 1944
+ D ++ P +L + ++W+PP + I GY ++ G+
Sbjct: 7899 EPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEK 7958
Query: 1945 -REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
V RP + G+ P EY + V A+ SEP
Sbjct: 7959 WMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEP 7999
Score = 107 bits (266), Expect = 2e-22
Identities = 292/1356 (21%), Positives = 513/1356 (37%), Gaps = 189/1356 (13%)
Query: 727 SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQ--YLDLPSTA--TSVNIPDLLP 782
+VTE+T+ V+SW D G ++++ + ++ + + + ++ S T + + LL
Sbjct: 15191 AVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 15249
Query: 783 GRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAP 837
G +YI VN Y + E E +L+ + PD P +P V + S+VV W P +
Sbjct: 15250 GNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDS- 15308
Query: 838 ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ-------PGVQYNITIYAVEENQEST 890
G + + VE N TL+DL+ G +Y I A S
Sbjct: 15309 -DGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISA 15367
Query: 891 PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNL 946
P P + + ++ + ++I W P S +TGY V++ L
Sbjct: 15368 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIA---L 15424
Query: 947 PGEHGQRLPIS----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD---A 999
P E ++ + T +TGL+ Y +++A++ +P T K +
Sbjct: 15425 PEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRML 15484
Query: 1000 PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR---QYNVGPSVSKYPLRNL 1056
P ++ + V +R RL V + R P + G S+ K ++
Sbjct: 15485 PPEIELDADLRKVVTIR------ACCTLRLFVPIKGRPAPEVKWARDHGESLDK---ASI 15535
Query: 1057 QPASEYTVSLVAIKGNQESPK----------ATGVFTTLQ----PGSSIPPYNTEVTETT 1102
+ S YT+ +V +S K + F ++ PG EVT+T+
Sbjct: 15536 ESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTS 15595
Query: 1103 IVITWTPAPRI--GFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQ 1154
+ +TW P P + G K+ + E+ R+ S S V L G Y + +
Sbjct: 15596 VTLTWDP-PLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYF--R 15652
Query: 1155 VLRDGQ------ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITG 1205
VL + + A V PL P ++ ++ +++SWE+ I G
Sbjct: 15653 VLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNS--VSLSWEKPEHDGGSRILG 15710
Query: 1206 YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKE-SVPI 1259
Y I T G + V +++ T L G EY+ V + D ++ SVP+
Sbjct: 15711 Y-IVEMQTKGSDKWATCATVKVTEATIT--GLIQGEEYSFRVSAQNEKGISDPRQLSVPV 15767
Query: 1260 --SDTIIPAVPPPTDLRFTNIGPDTMRV----TWAPPPSIDLTNFLVRYSPVKNEEDVAE 1313
D +IP FT + + ++V P P++ V P+K
Sbjct: 15768 IAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNV---PLK---QTTR 15821
Query: 1314 LSISPSDNAVVLTNLLPGTE----YVVSV-SSVYEQHESTPLRGRQKTGLDSPTG-IDFS 1367
++ ++N +LT E YVV + +S E E+ + K G PTG +
Sbjct: 15822 VNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG--PPTGPVKMD 15879
Query: 1368 DITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423
++TA+S T+ W P+ ++I Y + + + + +R +I L G E
Sbjct: 15880 EVTADSITLSWGPPKYDGGSSINNYIVEKR-DTSTTTWQIVSATVARTTIKACRLKTGCE 15938
Query: 1424 YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPT-------SLLISWDAP----A 1472
Y I A N +S L + TV+ P + TP S+ + W+ P
Sbjct: 15939 YQFRIAAENRYGKSTYL-NSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGG 15997
Query: 1473 VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSK 1532
V Y + E V+ P ++ +GL+ GV+Y V A G S
Sbjct: 15998 SRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKV 16057
Query: 1533 PISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTK 1588
R D P + + V NS++++W S +TGY V K
Sbjct: 16058 SECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKAS 16117
Query: 1589 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-SQPLVQT-AVTNIDR--PKGLAFTDVD 1644
T + GL Y V A+N +G S+P T A+T D P ++
Sbjct: 16118 FTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKY 16177
Query: 1645 VDSIKI-AWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVV 1703
D+I + A ES + Y P I + G+++ + L S + +
Sbjct: 16178 KDTIVVHAGESFKVDAD----IYGKPIPTIQWI----KGDQELSNTARLEIKSTDFATSL 16229
Query: 1704 ALHDD---------MESQPLIGTQSTAI-------PAPTD--LKFTQVTPTSLSAQWTPP 1745
++ D ++++ + G +S + P P + + + VT + W PP
Sbjct: 16230 SVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPP 16289
Query: 1746 NVQLTGYRV--RVTPKEKTGPM--KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1801
+Q G + + + +T + ++ + S V+ L+ +Y + A+
Sbjct: 16290 -LQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVG 16348
Query: 1802 RPAQGVVTTLEN--VSP--PRRARVTDATETTITISWRTKT----ETITGFQVDAVPANG 1853
P + +N V P P+ VT T+ ++ + W I G+ ++ G
Sbjct: 16349 EPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEG 16408
Query: 1854 --QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDA-STAID------ 1904
T + + ++R +TGL DY+ + N S P A A D
Sbjct: 16409 IRWTRCHKRLIGELR-LRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPG 16467
Query: 1905 APSNLRFLATTPNSLLVSWQPP----RARITGYIIK 1936
P+N + + T +S+ +SW P I GYI++
Sbjct: 16468 PPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVE 16503
Score = 106 bits (265), Expect = 2e-22
Identities = 338/1705 (19%), Positives = 582/1705 (34%), Gaps = 213/1705 (12%)
Query: 606 PSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGH 662
P GPVE+ + + W P S I YIL R + + W +
Sbjct: 14101 PGPPGPVEI----SNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRL-LWTVVSEDIQ 14155
Query: 663 LNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLV 722
+ L G Y ++ ++ YG E PV S V P
Sbjct: 14156 SCRHVATKLIQGNEYIFRVSAVNHYGKGE-------------PVQSEPVKMVDRFGPPGP 14202
Query: 723 ATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778
V+ +T ++ VSW D ++G+ VE + + + P + +
Sbjct: 14203 PEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVT 14262
Query: 779 DLLPGRKYIVNVYQISEDG------EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS 832
L G Y V + G +L P P +P V S + W
Sbjct: 14263 GLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWG 14322
Query: 833 RPQ----APITGYRIVYSPSVEGSSTELNLPETANSVT---LSDLQPGVQYNITIYAVEE 885
+P ITGY +V V + + TA +T + DLQ +YN I A+ +
Sbjct: 14323 KPHYDGGLEITGY-VVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAIND 14381
Query: 886 NQESTPVVIQQ-ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPV 944
P VI E + +L+ V ++I P V
Sbjct: 14382 AGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKD 14441
Query: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYF--KVFAVSHGRESKPLTAQQTTKLDAP-- 1000
N+ ++ + NT + + P Y K K LD P
Sbjct: 14442 NINLKNRANI---ENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGP 14498
Query: 1001 -TNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSK-----YPLR 1054
NL+ + T +V + W P G R+T + + + + + + +K Y +
Sbjct: 14499 VLNLRPTDITKDSVTLHWDLPLID-GGSRITNYIVEKREATRKSYSTATTKCHKCTYKVT 14557
Query: 1055 NLQPASEYTVSLVAIK--GNQESPKATGVFTTLQPGSSIPPYNT-EVTETTIVITWTPAP 1111
L EY ++A G E + T + S N ++T++T+ + W P P
Sbjct: 14558 GLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAW-PKP 14616
Query: 1112 R-------IGFKLGVRPSQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVL----RDG 1159
+ G+ + + +G + +T+ G VV LT G EY + + + R
Sbjct: 14617 KHDGGSKITGYVIEAQ-RKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSA 14675
Query: 1160 QERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE--RSTTPDITGYRITTTPTNGQQ 1217
P++ K T L L L V+ + + + P + + T T G Q
Sbjct: 14676 PRESRPVIVKEQTMLP---ELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQ 14732
Query: 1218 G-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAV-----PPPT 1271
+ V ++ T N++ + + Y + + D I V PP
Sbjct: 14733 ILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTG 14792
Query: 1272 DLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNL 1328
++F + D + +W PP + + ++N++V + V EL+ + T L
Sbjct: 14793 PIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWV-ELATTVIRTTYKATRL 14851
Query: 1329 LPGTEYVVSVSS-----VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAP- 1381
G EY V + V S + + P G + +T +S T+ W P
Sbjct: 14852 TTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPL 14911
Query: 1382 ---RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------ 1432
+ I GY + + + N + LT G Y ++A N
Sbjct: 14912 SDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSK 14971
Query: 1433 -GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1491
+ P+L P L + T T + W P T + +Y + P
Sbjct: 14972 PSKPSEPMLALDPIDPPGKPVPLNITRHTVT---LKWAKPEYTGGFKITSYIVEKRDLPN 15028
Query: 1492 QEFTVPG----SKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPS 1546
+ ++ T+SGL Y V A G SP S +I R +++ P
Sbjct: 15029 GRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPK 15088
Query: 1547 QMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTK------TKTAGPDQTEMTIE 1600
+D I +R+ P PT + G + E+ I
Sbjct: 15089 IKVDVKFKDTVI-------LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIA 15141
Query: 1601 GLQPTV---------EYVVSVYAQNPSGESQPLVQTAVTNIDRP----KGLAFTDVDVDS 1647
+ ++ A NP G ++ + V +DRP LA T+V +
Sbjct: 15142 DFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKV--LDRPGPPEGPLAVTEVTSEK 15199
Query: 1648 IKIAWESP---QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVA 1704
++W P G + + + A + + ++ L G+EY V+A
Sbjct: 15200 CVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMA 15259
Query: 1705 LH-----DDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPPN----VQLTGYRV 1754
++ + +ES+P++ P P + + T +T S+ W P+ ++ Y V
Sbjct: 15260 VNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIV 15319
Query: 1755 RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYA-----LKDTLTSRPAQGVVT 1809
K +K VSGL +YE + A + + P
Sbjct: 15320 ERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACD 15379
Query: 1810 TLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVD-AVPANGQTPIQRTIKP- 1863
T+ PP RV D + ++I+I+W ITG+ V+ A+P + I + P
Sbjct: 15380 TVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQI---VTPP 15436
Query: 1864 ---DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAS---------TAIDAPSNLRF 1911
SYTITGL +YKI +Y +N P ++ + I+ ++LR
Sbjct: 15437 AGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRK 15496
Query: 1912 LATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTI 1971
+ T + P +K+ + + I G +
Sbjct: 15497 VVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLIVGNVNRFDSGK 15556
Query: 1972 YVIALKNNQKSEPLIGRKKTDELP--------QLVTLPHPNL-HGPEILDVPSTVQKTPF 2022
Y++ ++N+ S+ + + P + VT L P +LD S ++ +
Sbjct: 15557 YILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKN--Y 15614
Query: 2023 VTHPGYDTGNGIQLPGTSGQQPS--VGQQM--------IFEEHGFRRTTPPTTATPIRHR 2072
+ T T+ + S V Q + E+ + P TA ++
Sbjct: 15615 IVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKAS 15674
Query: 2073 PRPYPPNVGQEALSQTT-----ISW-APFQDTSE----YIISCHPVGTDEEPLQFRVPGT 2122
RP PP G+ L T +SW P D YI+ G+D+ V
Sbjct: 15675 ERPLPP--GKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATV--K 15730
Query: 2123 STSATLTGLTRGATYNIIVEALKDQ 2147
T AT+TGL +G Y+ V A ++
Sbjct: 15731 VTEATITGLIQGEEYSFRVSAQNEK 15755
Score = 106 bits (264), Expect = 3e-22
Identities = 321/1571 (20%), Positives = 563/1571 (35%), Gaps = 259/1571 (16%)
Query: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWR 646
YG G+ +P++ P V + + N+ I+W P+ S I+ Y++ +
Sbjct: 18906 YGIGLPAETTEPVKVSEPPLPPGRVTLVDVTR--NTATIKWEKPESDGGSKITGYVVEMQ 18963
Query: 647 PKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPV 706
K S +W T L + TI GL G Y ++ ++ + G + + PV
Sbjct: 18964 TKGSE-KWSTCTQVKTLEA-TISGLTAGEEYVFRVAAVNEKGRSDPRQL-------GVPV 19014
Query: 707 TSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL 766
+ + E P L + +V V + +R + + +E +
Sbjct: 19015 IARDI--EIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVN-V 19071
Query: 767 DLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDP---TVDQVD 823
T TS++I + K V Y++ I D P P +D+V
Sbjct: 19072 SSSKTVTSLSIKE---ASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVS 19128
Query: 824 DTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNIT 879
SI + W+ P+ I+ Y + + + ++ S+ + L G +Y
Sbjct: 19129 CDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFR 19188
Query: 880 I-----YAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE--- 931
+ Y ES+ VV + P S P P + V T + + W P
Sbjct: 19189 VCAENRYGKSSYSESSAVVAEY-----PFSPPGP-PGTPKVVHATKSTMLVTWQVPVNDG 19242
Query: 932 -SAVTGYRVDVIP-VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA---VSHGRES 986
S V GY ++ ++ ++ I+ +T +V+GL G+ Y ++V+A G+ S
Sbjct: 19243 GSRVIGYHLEYKERSSILWSKANKILIA-DTQMKVSGLDEGLMYEYRVYAENIAGIGKCS 19301
Query: 987 K---PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR----AQITGY-----RLTVG-- 1032
K P+ A+ D P + N T +V ++W+ P A+ITGY L G
Sbjct: 19302 KSCEPVPARDPC--DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRW 19359
Query: 1033 --------------LTRRGQPRQY-------NVGPSVSKYPLRNLQPASEYTVSLVAIKG 1071
+T + ++Y N SVS+ SE T ++ +K
Sbjct: 19360 LKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSE--------PSESTGPII-VKD 19410
Query: 1072 NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGF-KLGVRPSQGGEAPRE 1130
+ E P+ V ++ I EV + I P P I + K G+ +
Sbjct: 19411 DVEPPR---VMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEII 19467
Query: 1131 VTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGV 1190
T + + V Y + + R + KV+ PP LE N T
Sbjct: 19468 STDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAG-PLEINGLTAE 19526
Query: 1191 -LTVSWERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY--- 1243
++SW R DI Y + T+ E + +SC L G EY
Sbjct: 19527 KCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQ--MTSCKVTKLLKGNEYIFR 19584
Query: 1244 --NVSVYTVKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTN 1297
V+ Y V + ESV I VP PPT L T++ ++M + W+ P S +++
Sbjct: 19585 VTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISG 19644
Query: 1298 FLVRYSPVKNEEDVAELSISP-SDNAVVLTNLLPGTEYVVSV-----SSVYEQHESTPL- 1350
+++ KN ++ P D V T L G EY V + + E++PL
Sbjct: 19645 YIIERRE-KNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLI 19703
Query: 1351 RGRQKTGLDS-PTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDR 1405
R L S P+ D + T+ W+ P A ITGY + + + +
Sbjct: 19704 RAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEY--KKSDDTDWKTS 19761
Query: 1406 VPHSRNS-ITLTNLTPGTEYVVSIVALN-----------------GREESPLLIGQQSTV 1447
+ R + T++ LT G EYV + ++N REE PL
Sbjct: 19762 IQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLF----DID 19817
Query: 1448 SDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT-VPGSKSTATI- 1505
S++ + L V A ++ + + V + + + + + + S+++ TI
Sbjct: 19818 SEMRKTLIVKAGASFTMTVPFRGRPVP----NVLWSKPDTDLRTRAYVDTTDSRTSLTIE 19873
Query: 1506 -SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW-L 1563
+ YT+T+ V A+S + + P+ + V DV S + W +
Sbjct: 19874 NANRNDSGKYTLTIQNVLS-----AASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDV 19928
Query: 1564 PSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
P + +PV Y + + T ++ + LQ Y V +N G
Sbjct: 19929 PENDGGAPVKNYHIEKREASKKAWVSV-TNNCNRLSYKVTNLQEGAIYYFRVSGENEFGV 19987
Query: 1621 SQPLVQTAVTNIDR----PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTY--SSPEDGIH 1674
P I P+ L T + DS+ + W P+ V Y + E G
Sbjct: 19988 GIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQK 20047
Query: 1675 ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVT 1734
+ + GLR SEY V A E+Q + P +L +
Sbjct: 20048 NWVKCAVAKSTHHVVSGLRENSEYFFRVFA-----ENQ-------AGLSDPREL----LL 20091
Query: 1735 PTSLSAQWTPPNVQL-----------TGYRVRVTPKEKTGPMKEINLAPD---------- 1773
P + Q PP + + G ++V P+ ++ L+ D
Sbjct: 20092 PVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRF 20151
Query: 1774 SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV------VTTLENVSPPR-RARVTDAT 1826
++ + L + K V+ A + +T+ + G + L+ PP ++D T
Sbjct: 20152 NTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDIT 20211
Query: 1827 ETTITISWR---------------TKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTIT 1871
E ++T+ W K ET T AV + RT+ +
Sbjct: 20212 EESVTLKWEPPKYDGGSQVTNYILLKRETST-----AVWTEVSATVARTM------MKVM 20260
Query: 1872 GLQPGTDYKIYL-----YTLNDNARSSPVVIDASTAIDAPSNLRFLA-TTPNSLLVSWQP 1925
L G +Y+ + + ++D+ S+ V + P + ++ T S+ V W
Sbjct: 20261 KLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHE 20320
Query: 1926 P----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL----- 1976
P + + GY ++ + S + + T +T + G Y V A
Sbjct: 20321 PVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGV 20380
Query: 1977 -KNNQKSEPLI 1986
K + SEP++
Sbjct: 20381 GKPSHPSEPVL 20391
Score = 106 bits (264), Expect = 3e-22
Identities = 279/1348 (20%), Positives = 495/1348 (36%), Gaps = 168/1348 (12%)
Query: 773 TSVNIPDLLPGRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSI 827
TS + LL G +YI VN Y + E E I + T P P + V S+
Sbjct: 19568 TSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESM 19627
Query: 828 VVRWSRPQAP----ITGYRIVYSPSVEGSSTELNL-PETANSVTLSDLQPGVQYNITIYA 882
+ WSRP++ I+GY I +N P V + L+ G +Y +YA
Sbjct: 19628 TLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYA 19687
Query: 883 VEENQESTPVVIQQETTGTPRSDT---VPSPRDL-QFVEVTDVKVTIMWTPP----ESAV 934
+ + + + ET+ R++ +PSP + V+ +TI W P + +
Sbjct: 19688 ----ENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPI 19743
Query: 935 TGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA--- 991
TGY V+ + + + R T ++GL+ G Y F+V +V+ S P +
Sbjct: 19744 TGYTVEYKKSD-DTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDP 19802
Query: 992 QQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP------------ 1039
Q + + +E T++V+ G T+ + RG+P
Sbjct: 19803 QIAKEREEEPLFDIDSEMRKTLIVK--------AGASFTMTVPFRGRPVPNVLWSKPDTD 19854
Query: 1040 ---RQYNVGPSVSKYPLR----NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIP 1092
R Y V + S+ L N + +YT+++ + V T P ++I
Sbjct: 19855 LRTRAY-VDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNIT 19913
Query: 1093 PYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDSG--SIVVSGLT 1144
+VT+ + V++W AP + + R + +A VT++ S V+ L
Sbjct: 19914 VQ--DVTKESAVLSWDVPENDGGAPVKNYHIEKREASK-KAWVSVTNNCNRLSYKVTNLQ 19970
Query: 1145 PGVEYVYTIQVLRD---GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW---ERS 1198
G Y + + + G + K+ SPP L + + V +++W E
Sbjct: 19971 EGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSV-SLTWLKPEHD 20029
Query: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
I Y + Q N ++ V A + L EY V+ S P
Sbjct: 20030 GGSRIVHYVVEALEKG--QKNWVKCAV-AKSTHHVVSGLRENSEYFFRVFAENQAGLSDP 20086
Query: 1259 ISDTIIPAV------PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVA 1312
+ ++P + PP D++ N T+ V +D+ V D
Sbjct: 20087 -RELLLPVLIKEQLEPPEIDMK--NFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGV 20143
Query: 1313 ELSISPSDNA-VVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD--------SPTG 1363
L + N + NL + V+ + + + G K ++ PTG
Sbjct: 20144 PLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTG 20203
Query: 1364 -IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNL 1418
+ SDIT S T+ W P+ + +T Y + E + E +R + + L
Sbjct: 20204 PVVISDITEESVTLKWEPPKYDGGSQVTNYILLKR-ETSTAVWTEVSATVARTMMKVMKL 20262
Query: 1419 TPGTEYVVSIVALNGR------EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA 1472
T G EY I A N + + + + T P V T S+ + W P
Sbjct: 20263 TTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPV 20322
Query: 1473 VT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSP 1528
V Y + + + + + ++ + G+ Y VYA G
Sbjct: 20323 SNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGK 20382
Query: 1529 ASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGP 1584
S + + P +++TD+ NS+S+ W S +TGY V
Sbjct: 20383 PSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRW 20442
Query: 1585 TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-SQPL-VQTAVTNIDRPKGLAFTD 1642
TK +T+ I GL +Y V+A+N G S P V +T ID G D
Sbjct: 20443 TKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVI-D 20501
Query: 1643 VDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSV 1702
+ ++ ++ + G + R S E + D E T L + ++ +
Sbjct: 20502 LPLEYTEVV-KYRAGTSVKLRAGISGKPAPTIEWYK-DDKELQTNALVCVENTTDLASIL 20559
Query: 1703 VALHDDMES-------QPLIGTQSTAI---------PAPTDLKFTQVTPTSLSAQWTPP- 1745
+ D + S + +G+ S I P ++F VT ++ W PP
Sbjct: 20560 IKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPA 20619
Query: 1746 ---NVQLTGYRVRVTPKEKTGPM--KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT 1800
++T Y + K +T + ++ + + + ++ +Y V A+
Sbjct: 20620 DDGGAKITHY---IVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGI 20676
Query: 1801 SRPAQGVVTTLENV----SPPRRARVTDATETTITISWRTKT----ETITGFQV---DAV 1849
P + +N PP VT T+ ++T+ W I+G+ + D
Sbjct: 20677 GEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKK 20736
Query: 1850 PANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNAR---SSPVVI-DASTAIDA 1905
++ TI+ D R +TGL +DY+ + +N + S P A+ ID
Sbjct: 20737 SLGWFKVLKETIR-DTRQ-KVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDP 20794
Query: 1906 P---SNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVP-RPRPGVTE 1957
P + +R +T +S+ + W P + +TGY+++ + V + TE
Sbjct: 20795 PGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTE 20854
Query: 1958 ATITGLEPGTEYTIYVIALKNNQKSEPL 1985
++ L+PG Y V A+ + EP+
Sbjct: 20855 YVVSNLKPGVNYYFRVSAVNCAGQGEPI 20882
Score = 103 bits (256), Expect = 3e-21
Identities = 283/1422 (19%), Positives = 486/1422 (34%), Gaps = 190/1422 (13%)
Query: 730 EITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRK 785
+IT S ++W D ++G+ VE + +D T +PDL+ G++
Sbjct: 7126 DITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFV-TDLEFTVPDLVQGKE 7184
Query: 786 YIVNVYQISE--DGEQSLILSTSQTTAPDAPPDP--TVDQVDDT--SIVVRWSRPQ---- 835
Y+ V ++ GE + + + P PDP V D T SI + W P+
Sbjct: 7185 YLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGG 7244
Query: 836 APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ 895
+ I GY + P P + ++ L+ G Y + A+ S P
Sbjct: 7245 SRIKGYIVERCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPT 7304
Query: 896 QETTGTPRSDTVPSPRDLQFVEVTDVKV-------TIMWTPPESAVTGYRVDVIPVNLPG 948
+E + D++ + VK + PE +T + D+I
Sbjct: 7305 EEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKR 7364
Query: 949 EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE 1008
+ +P + S TY + V GR + + K P +
Sbjct: 7365 ITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVC-GRATAVVEVNVLDKPGPPAAFDITDV 7423
Query: 1009 TDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTV 1064
T+ + L+ W PPR ++IT Y + T + + + + L P EY
Sbjct: 7424 TNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIF 7483
Query: 1065 SLVA--IKGNQESPKATGVFTTLQPGSSIPPYNTE---VTETTIVITWTP------APRI 1113
+ A + G E +A+ + Q PP E +T+ + +TW +P
Sbjct: 7484 RVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPIT 7543
Query: 1114 GF---KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTI---QVLRDGQERDAPIV 1167
G+ +L + + D+ + V GLT +Y + + + G+ +
Sbjct: 7544 GYWVERLDPDTDKWVRCNKMPVKDT-TYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEP 7602
Query: 1168 NKVVTPLSPPTNLHLEANPDTGVLTV--SWERSTTPDITGYRITTTPTNGQQGNSLEEVV 1225
+ P+ PP D G +V +W T P+ G + +E V
Sbjct: 7603 ILIKDPIDPPWPPGKPTVKDVGKTSVRLNW---TKPEHDGGAKIESYVIEMLKTGTDEWV 7659
Query: 1226 HADQSSCTFDNLSPGL----EYNVSVYTVKDDKESVPI--SDTIIPAVP-----PPTDLR 1274
+ T +L PGL EY+ V V ES P SD ++ PP L
Sbjct: 7660 RVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLE 7719
Query: 1275 FTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
NI +T + W P +TN++V V+ + + + D +T L G
Sbjct: 7720 VINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRK-GWQTVDTTVKDTKCTVTPLTEG 7778
Query: 1332 TEYVVSVS-------SVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR-- 1382
+ YV V+ S Y + E + L T P + D+T + W P+
Sbjct: 7779 SLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKND 7838
Query: 1383 --ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREE 1436
I Y I + + + + +T++ GTE + A N G
Sbjct: 7839 GGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPS 7898
Query: 1437 SP---LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQE 1493
P L I ++ P DL V A + I+W P E G SP+
Sbjct: 7899 EPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPP------------EKNGGSPIIG 7946
Query: 1494 FTVP----GSKSTATIS-------------GLKPGVDYTITVYAVTGRGDSPASSKPISI 1536
+ V G++ ++ G+ P +Y + V AV G S+P I
Sbjct: 7947 YHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIG----VSEPSEI 8002
Query: 1537 NYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1596
+ P D++ + I V S +R P + D+
Sbjct: 8003 SENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLT 8062
Query: 1597 MTIEGLQPTVEYVVSVYA---------QNPSGESQPLVQTAVTNIDRP-KGLAFTDVDVD 1646
M + + +E SV A +N G + + V + P K + +D+
Sbjct: 8063 MKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKS 8122
Query: 1647 SIKIAWESPQ--GQVSRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVSVV 1703
S K+ WE P+ G E G P GE + ++ L P EY V
Sbjct: 8123 SCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVK 8182
Query: 1704 ALH-----DDME-SQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPP----NVQLTGY 1752
A++ + +E P+I P P D++ T +++ W PP ++ GY
Sbjct: 8183 AVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGY 8242
Query: 1753 RV-RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTL 1811
+ ++ E+ +L P + GL +Y+ V A S P++ T
Sbjct: 8243 IIEKIAKGEERWKRCNEHLVP-ILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPT- 8300
Query: 1812 ENVSPPRRARVTDATETTI------------------TISWRTKTETITGFQVD------ 1847
+ V P +V T + TI+W I ++
Sbjct: 8301 KAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPL 8360
Query: 1848 --------------AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL-NDNA-R 1891
+P + I + K + + L+P D+ +Y+ + ND+
Sbjct: 8361 VRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRP--DHGLYMIKVENDHGIA 8418
Query: 1892 SSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPRE- 1946
+P + P N F S+L W+PP + I Y ++ + P E
Sbjct: 8419 KAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEW 8478
Query: 1947 VVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGR 1988
+V + ++T L G EY V A P + +
Sbjct: 8479 IVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSK 8520
Score = 101 bits (252), Expect = 8e-21
Identities = 253/1300 (19%), Positives = 457/1300 (35%), Gaps = 239/1300 (18%)
Query: 718 FSPLVATSESVTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTA- 772
F P T+ + + T +S ++W + G+ VE + + +E + P T
Sbjct: 17546 FKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVE--ICKADEEEWQIVTPQTGL 17603
Query: 773 --TSVNIPDLLPGRKYIVNVYQISEDG--EQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828
T I L ++Y + V +++ G E + + T + P+ +D IV
Sbjct: 17604 RVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIV 17663
Query: 829 VRW---SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYN-ITIYAVE 884
VR +R P G +P + S E + ++ GV Y ++I +
Sbjct: 17664 VRAGGSARIHIPFKGRP---TPEITWSREEGEFTDKVQ------IEKGVNYTQLSIDNCD 17714
Query: 885 ENQESTPVVIQQETTGTPRS-------DTVPSPRDLQFVEVTDVKVTIMWTPP----ESA 933
N ++ + ++G+ + DT P++L EV ++W PP +
Sbjct: 17715 RNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAK 17774
Query: 934 VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ 993
V Y +D S+ +F +V L+ G YYF+V A + P+
Sbjct: 17775 VKNYVIDKRESTRKAYANVSSKCSKTSF-KVENLTEGAIYYFRVMAENEFGVGVPVETVD 17833
Query: 994 TTKLDAP------TNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYN 1043
K P L V++T ++++ W P +++ GY V + +G +
Sbjct: 17834 AVKAAEPPSPPGKVTLTDVSQTSASLM--WEKPEHDGGSRVLGY--VVEMQPKGTEKWSI 17889
Query: 1044 VGPS-VSKYPLRNLQPASEYTVSLVAIKGNQES-PKATGV-----FTTLQPGSSIPPYNT 1096
V S V + L EY + A +S P+ GV T+QP + P+NT
Sbjct: 17890 VAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKL-PFNT 17948
Query: 1097 EVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVL 1156
+ G + E+ V+ P + +V
Sbjct: 17949 YSIQA----------------------GEDLKIEIP------VIGRPRPNISWV------ 17974
Query: 1157 RDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQ 1216
+DG+ PL T +++E + VL + + D Y +T T + G
Sbjct: 17975 KDGE------------PLKQTTRVNVEETATSTVLHI--KEGNKDDFGKYTVTATNSAGT 18020
Query: 1217 QGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFT 1276
+L +V PG PP +RF
Sbjct: 18021 ATENLSVIVLE----------KPG---------------------------PPVGPVRFD 18043
Query: 1277 NIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLP 1330
+ D + ++W PP ++N++V K + +S + + + +T L
Sbjct: 18044 EVSADFVVISWEPPAYTGGCQISNYIVE----KRDTTTTTWHMVSATVARTTIKITKLKT 18099
Query: 1331 GTEYVVSVSSVYEQHESTPLRGR-----QKTGLDSPTGIDF-SDITANSFTVHWIAP--- 1381
GTEY + + +S PL + P G F + I+ + V W P
Sbjct: 18100 GTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVND 18159
Query: 1382 -RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440
I GY + ++ + ++ P T L G EY + A E+ +
Sbjct: 18160 GGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSA-----ENIVG 18214
Query: 1441 IGQQSTVS---------DVPRDLEVVAATPTSLLISWDAPAV----TVRYYRITYGETGG 1487
IG+ S VS D P E + T ++ + W PA + Y + +
Sbjct: 18215 IGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPD 18274
Query: 1488 NSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPS 1546
++ ++ T+SGL Y V A G+ S S +I R EID P+
Sbjct: 18275 GRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPN 18334
Query: 1547 QMQVTDVQDNSI--SVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
+D + + + + + G + + G +TA + + TI+
Sbjct: 18335 ASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTL 18394
Query: 1605 TV---------EYVVSVYAQNPSG-ESQPLVQTAVTNIDRPKG-LAFTDVDVDSIKIAWE 1653
V +Y++ + N G +S P+ + P+G L T V + +AW
Sbjct: 18395 VVKDCIRTDGGQYILKL--SNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWN 18452
Query: 1654 SP----QGQVSRY--------RVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVS 1701
P +S Y R++++ + L ++ L PG+EY
Sbjct: 18453 PPLQDGGANISHYIIEKRETSRLSWTQVSTEVQAL---------NYKVTKLLPGNEYIFR 18503
Query: 1702 VVALH-----DDMESQPLIGTQSTAIPAPTDL-KFTQVTPTSLSAQWTPP----NVQLTG 1751
V+A++ + +ES P+ P P + + +T S+ W P ++ G
Sbjct: 18504 VMAVNKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEG 18563
Query: 1752 YRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVV--- 1808
Y + KE K + V+GL YE V A P++ V
Sbjct: 18564 YILEKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYR 18623
Query: 1809 --TTLENVSPPRRARVTDATETTITISWRTKT----ETITGF--QVDAVPANGQTPIQRT 1860
L PP +VTD + ++++++W + G+ +V A+ T
Sbjct: 18624 ACDALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPP 18683
Query: 1861 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAS 1900
+ +T+T L+ T+Y + +N P + S
Sbjct: 18684 TGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGS 18723
Score = 101 bits (252), Expect = 8e-21
Identities = 308/1501 (20%), Positives = 533/1501 (35%), Gaps = 204/1501 (13%)
Query: 624 NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNS--YTIKGLKPGVVYE 678
NS + W P+ S I +YIL R K S RW + ++ + + GL G YE
Sbjct: 21794 NSITLTWARPESDGGSEIQQYILERREKKST-RWVKVISKRPISETRFKVTGLTEGNEYE 21852
Query: 679 GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
+++ G + PV P P V VT+ + ++ +
Sbjct: 21853 FHVMAENAAGVGPASGIS-RLIKCREPVNP--------PGPPTVV---KVTDTSKTTVSL 21900
Query: 739 SW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQIS 794
W + G+ +E ++ GD + T + DL G +Y V I+
Sbjct: 21901 EWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAIN 21960
Query: 795 EDGEQSLILSTSQTTAPD--APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGS 852
G+ T A D P+ +D + VVR Y+ +P+ S
Sbjct: 21961 GAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWS 22020
Query: 853 STELNLPETANSVTLSDLQPGVQYNIT-------IYAVEENQESTPVVIQQETTGTPRSD 905
+ NL A+ T N VE N S + + TP
Sbjct: 22021 KPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP- 22079
Query: 906 TVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
P + F +VT T+MW P + + Y V+ + +R F
Sbjct: 22080 ----PGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIF 22135
Query: 962 AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ----TTKLDAPTNLQFVNETDSTVLVRW 1017
+V L+ GV YYF+V AV+ +P + T + P L V+ + S+ ++ W
Sbjct: 22136 -KVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAW 22194
Query: 1018 TPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEY---------- 1062
P ++ITGY L + ++G G + + + L +EY
Sbjct: 22195 LKPDHDGGSRITGYLLE--MRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDA 22252
Query: 1063 -------TVSLVAIKGNQESPKA--TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI 1113
S V IK Q P A TG+ L + P+ +V I+ PAP++
Sbjct: 22253 GYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVP-----ISGRPAPKV 22307
Query: 1114 GFKL-GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT 1172
+KL +R + T D ++ V G Y + + + + V+
Sbjct: 22308 TWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIG 22367
Query: 1173 PLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQ 1229
P T ++ +SW + +IT Y + + + V Q
Sbjct: 22368 RPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQ 22427
Query: 1230 SSCTFDNLSPGLEYNVSV-----YTVKDDKESVPISDTIIPAVPP--PTDLRFTNIGPDT 1282
T +L+ +EY+ V + V ES PI P VPP PT ++ +
Sbjct: 22428 IKVT--HLTKYMEYSFRVSSENRFGVSKPLESAPII-AEHPFVPPSAPTRPEVYHVSANA 22484
Query: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEED----VAELSISPSDNAVVLTNLLPGTE----- 1333
M + W P D + ++ Y K E + V E + + +T L+ G E
Sbjct: 22485 MSIRWEEPYH-DGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRT 22543
Query: 1334 YVVSVSSVYEQHE-STPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGY 1388
Y ++ + V + E S P+ + +D+P + +D+T ++ ++ W AP + + GY
Sbjct: 22544 YALNAAGVSKASEASRPIMAQNP--VDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGY 22601
Query: 1389 RIRHHPEHFSGRPREDRVPH---SRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS 1445
I P G R + + S N T+T L+ G Y ++A N + G +S
Sbjct: 22602 IIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNA--AGVISKGSES 22659
Query: 1446 TVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI 1505
T RD + D + + GG + G K
Sbjct: 22660 TGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLC 22719
Query: 1506 SGLKPGVDYT----ITVYAVTGRGDS---------PASSKPISINYRTEIDKP---SQMQ 1549
K + YT V R DS + +K +S+ + +D P ++
Sbjct: 22720 E--KVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV-LDSPGPCGKLT 22776
Query: 1550 VTDVQDNSISVKW-LP---SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPT 1605
V+ V ++ W LP + +T Y V + +T+ + + +EG PT
Sbjct: 22777 VSRVTQEKCTLAWSLPQEDGGAEITHYIV----------ERRETSRLNW--VIVEGECPT 22824
Query: 1606 VEYVVS-----------VYAQNPSG-----ESQPLVQTAVTNIDRPKGL-AFTDVDVDSI 1648
+ YVV+ V A N G ES+P+V I P G+ + I
Sbjct: 22825 LSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHI 22884
Query: 1649 KIAWESPQ----GQVSRYRVTYSSPED----GIHELFPAPDGEEDTAELQGLRPGSEYTV 1700
I W P+ ++S Y V + +++ + D ++ L G +Y
Sbjct: 22885 IIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYD---TRLKVTSLMEGCDYQF 22941
Query: 1701 SVVALHDDMESQP------LIGTQSTAIPAPTDL-KFTQVTPTSLSAQWTPP----NVQL 1749
V A++ S+P + + + P P + T S+S WT P +
Sbjct: 22942 RVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDI 23001
Query: 1750 TGYRVRVTPKEKTGPMK-EINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV- 1807
GY + + K+ + N ++ V L + KY V A+ S ++ +
Sbjct: 23002 VGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIA 23061
Query: 1808 -VTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPA-----NGQTPIQRTI 1861
+ +E + P + D + T+TI + P G R I
Sbjct: 23062 EIEPVERIEIP-DLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAI 23120
Query: 1862 KPDVRSYTITGLQPGTDYKIYLYTL---NDNARSSPVVIDASTAIDAP-SNLRFLATTPN 1917
SY++ + Y YT+ N + + S V+ P +++ + +
Sbjct: 23121 IDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRD 23180
Query: 1918 SLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYV 1973
S+ ++W+ P A + YI++ + + V + T I+GL GT Y V
Sbjct: 23181 SVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTV-TTKCSKTLYRISGLVEGTMYYFRV 23239
Query: 1974 I 1974
+
Sbjct: 23240 L 23240
Score = 98.2 bits (243), Expect = 8e-20
Identities = 288/1429 (20%), Positives = 523/1429 (36%), Gaps = 305/1429 (21%)
Query: 624 NSHPIQWNAPQPSHISKYILRW---RPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQ 680
N+ I+W P SK I W + +N++ KE +P +Y + GL G+ Y+ +
Sbjct: 22483 NAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFR 22542
Query: 681 LISIQQYGHQEVTRFDFTTTSTSTPVTS-NTVTGETTPFSPLVATSESVTEITASSFVVS 739
++ G + + S P+ + N V P VT++T S+ +
Sbjct: 22543 TYALNAAGVSKASE-------ASRPIMAQNPVDAPGRP---------EVTDVTRSTVSLI 22586
Query: 740 WVSAS----DTVSGFRVEYELSEEGDEPQYLDLPSTATSVN---IPDLLPGRKYIVNVYQ 792
W + + V G+ +E + E + ++L T S N + L G Y V
Sbjct: 22587 WSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLA 22646
Query: 793 ISEDGEQSLILSTSQTTAPD------APPDPTVD-QVDDTSIVVRWSRPQAPITGYRIVY 845
+ G +I S++T P APP +D ++ + +R G +V
Sbjct: 22647 KNAAG---VISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIR--------AGSDLVL 22695
Query: 846 SPSVEGS----------STELNLPETANS----------VTLSDLQPGVQYNITIYAVEE 885
+V G EL+L E + + D +Y +T+
Sbjct: 22696 DAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASG 22755
Query: 886 NQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDV 941
+ + +V ++ G TV VT K T+ W+ P+ + +T Y V+
Sbjct: 22756 TKAVSVMVKVLDSPGPCGKLTVS--------RVTQEKCTLAWSLPQEDGGAEITHYIVE- 22806
Query: 942 IPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYY-----------FKVFAVS-HGR----E 985
R SR + V G P ++Y F+V AV+ +G E
Sbjct: 22807 -----------RRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVE 22855
Query: 986 SKPLTAQQTTKLDAPTNL-QFVNETDSTVLVRWTPPRA----QITGYRLTVGLTRRGQPR 1040
S+P+ A+ + + +P + + V ++++WT P + +I+ Y V + R
Sbjct: 22856 SEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNY--LVDKREKKSLR 22913
Query: 1041 QYNVGPSVSKYPLR----NLQPASEYTVSLVAIK--GNQESPKATGVFTTLQPGSSIPPY 1094
V Y R +L +Y + A+ GN E +A+ + +P
Sbjct: 22914 WTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREP------- 22966
Query: 1095 NTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTP----GVEYV 1150
++TP P PS APR V + SI ++ P G + V
Sbjct: 22967 -----------SYTPGP---------PS----APRVVDTTKHSISLAWTKPMYDGGTDIV 23002
Query: 1151 -YTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDIT----- 1204
Y +++ QE+D +V H A T+ T PD+
Sbjct: 23003 GYVLEM----QEKDTDQWYRV----------HTNA-------TIRNTEFTVPDLKMGQKY 23041
Query: 1205 GYRITTTPTNG--QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDT 1262
+R+ G + S+ E+ ++ L+ L+ V++ + V +S
Sbjct: 23042 SFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGR 23101
Query: 1263 IIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNA 1322
PPP +TW+ IDL + + + E + L +
Sbjct: 23102 -----PPPV-------------ITWSKQ-GIDLASRAI----IDTTESYSLLIVDK---- 23134
Query: 1323 VVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR 1382
N +Y + + + +T L T P+ + +++ +S T+ W P
Sbjct: 23135 ---VNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPS-VKVKEVSRDSVTITWEIPT 23190
Query: 1383 ----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITL---TNLTPGTEYVVSIVALNGRE 1435
A + Y + E R + ++ S TL + L GT Y ++
Sbjct: 23191 IDGGAPVNNYIV----EKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLP----- 23241
Query: 1436 ESPLLIGQQSTVSD---------VPRDLEVVAATPTSLLISWDAPAVT----VRYYRITY 1482
E+ IG+ SD VP LEVV T +++ ++W+ P + Y +
Sbjct: 23242 ENIYGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEA 23301
Query: 1483 GETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEI 1542
+ G ++ T+ + T++ L G Y + A +G S ++ +
Sbjct: 23302 CKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLR 23361
Query: 1543 DKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGP------------------ 1584
P+ + ++ + +I V P+ PV P G P
Sbjct: 23362 VLPT-IDLSTMPQKTIHV---PAGRPVE----LVIPIAGRPPPAASWFFAGSKLRESERV 23413
Query: 1585 ---TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKG--LA 1639
T TK A E TI + T EY + + +N +G + ++ + + P +
Sbjct: 23414 TVETHTKVAKLTIRETTI---RDTGEYTLEL--KNVTGTTSETIKVIILDKPGPPTGPIK 23468
Query: 1640 FTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEE---DTAELQGLRPGS 1696
++D SI I+WE P+ Y + H P E T + L G+
Sbjct: 23469 IDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGN 23528
Query: 1697 EYTVSVVALH-----DDMESQPLIGTQSTAIPAPTD-LKFTQVTPTSLSAQWTPPN---- 1746
EY V A + ++S+ + S IP P + L+ V+ ++ W PP
Sbjct: 23529 EYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGG 23588
Query: 1747 VQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVS-GLMVATKYEVSVYALK---DTLTSR 1802
Q+TGY V + + +N P + + S GL +YE V A+ SR
Sbjct: 23589 SQVTGYIVE-RKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSR 23647
Query: 1803 PAQGVVTTLENVSPP---RRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQT 1855
P++ +V ++ ++PP + RVTD T T+++++W + +TG+ ++ +
Sbjct: 23648 PSKPIVA-MDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHE 23706
Query: 1856 PIQ-RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI 1903
+ T +R YT+T L G +Y+ + N P + + +
Sbjct: 23707 WTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKV 23755
Score = 97.1 bits (240), Expect = 2e-19
Identities = 340/1573 (21%), Positives = 568/1573 (36%), Gaps = 223/1573 (14%)
Query: 619 TPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
T S +S +QWN P S + Y L + +NS+ K P + GL+ GV
Sbjct: 15978 TLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGV 16037
Query: 676 VYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASS 735
YE ++ + G P + P P E++ +T +S
Sbjct: 16038 EYEFRVSAENIVG-------------IGKPSKVSECYVARDPCDP-PGRPEAII-VTRNS 16082
Query: 736 FVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVY 791
+ W ++G+ VE + EG + T + L+ +Y V
Sbjct: 16083 VTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVI 16142
Query: 792 QISEDGEQSLIL-STSQTTAPDA--PPDPTVDQVDDTSIVVRWS---RPQAPITGYRIVY 845
+ G S ST TA D PP ++D +IVV + A I G I
Sbjct: 16143 ARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPI-- 16200
Query: 846 SPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
P+++ + L TA + +D + + +S +++ + RS
Sbjct: 16201 -PTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV-----DSGNYILKAKNVAGERS 16254
Query: 905 DTV-------PSPRDLQFV--EVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP 955
TV P P + V VT K T+ W PP + D+I + RL
Sbjct: 16255 VTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPP---LQDGGSDIINYIVERRETSRLV 16311
Query: 956 IS------RNTFAEVTGLSPGVTYYFKVFAVS-----HGRESKPLTAQQTTKL-DAPTNL 1003
+ + +VT L G Y F++ AV+ ES+P+ A+ + DAP
Sbjct: 16312 WTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAP 16371
Query: 1004 QFVNETDSTVLVRWTPPRA----QITGYRLTV----GLTRRGQPRQYNVGPSVSKYPLRN 1055
+ T +++V W P + +I GY L G+ R + + +G +
Sbjct: 16372 EVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGI-RWTRCHKRLIGELRLRVTGLI 16430
Query: 1056 LQPASEYTVSLVAIKGNQE-SPKAT---GVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
E+ VS G E SP + +PG P ++T +++ ++W+
Sbjct: 16431 ENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPI 16490
Query: 1112 RIGF---------KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD---G 1159
G K V + + +I V L EY + I + G
Sbjct: 16491 YDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVG 16550
Query: 1160 QERDAPIVNKVVTPL-SPPTNLHLEANPDTGV-------LTVSWERSTTPDITGYRITTT 1211
+ D P V L +P +L LE + L V + TP++ ++
Sbjct: 16551 EHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKV--- 16607
Query: 1212 PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV----KDDKESVPISDTIIPAV 1267
+G+ ++ V + +S DN++ Y+ YT+ +S ++ ++
Sbjct: 16608 --DGEIRDAAIIDVTSSFTSLVLDNVN---RYDSGKYTLTLENSSGTKSAFVTVRVLDTP 16662
Query: 1268 PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAELSISPSDNAVV 1324
PP +L+ T I D++ +TW PP +D + + Y K E + A + + N+
Sbjct: 16663 SPPVNLKVTEITKDSVSITW-EPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWK 16721
Query: 1325 LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL----DSPTGIDFSDITANSFTVHWIA 1380
+ L G Y V++ E P + + P I D+T NS ++ W
Sbjct: 16722 IDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTK 16781
Query: 1381 PR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436
P + I Y + +H RV + +TNLT G EY+ +VA+N +
Sbjct: 16782 PEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQ--AVITNLTQGEEYLFRVVAVNEKGR 16839
Query: 1437 S-PLLIGQQSTVSDVPRDLEVVAA-TPTSLLISWD----APAVTVRYYRITYGETGGNSP 1490
S P + D+ + +V A + S+ + D P IT+ + G P
Sbjct: 16840 SDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDG--LP 16897
Query: 1491 VQEFT---VPGSKSTATIS----GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
+++ T V S T+S G Y ITV V G+ K SI T +D
Sbjct: 16898 LKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQ-------KTASIEIVT-LD 16949
Query: 1544 KP----SQMQVTDVQDNSISVKWLP----SSSPVTGYRV-----TTTPKNGPGPTKTKTA 1590
KP ++ DV SI++ W P +T Y V TTT + T +T
Sbjct: 16950 KPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTT 17009
Query: 1591 GPDQTEMTIEGLQPTVEYVVSVYAQNPSG-----ESQPLVQTAVTNIDRPKGLAF-TDVD 1644
+ + L+ EY ++A+N G ES P+V P G F T +
Sbjct: 17010 ------LKVTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAIS 17063
Query: 1645 VDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE---EDTA-ELQGLRPGSEYTV 1700
DS+ I W P + Y + + + DT + Q L G EY
Sbjct: 17064 KDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEF 17123
Query: 1701 SVVALHDDMESQPLIGTQSTAIPAPTDLKFT----QVTPTSLSAQWTPP----NVQLTGY 1752
V A + + ++ P D T V ++ QWT P +TGY
Sbjct: 17124 RVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGY 17183
Query: 1753 RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT-LTSRPAQ--GVVT 1809
V MK + VSGL +YE V A S+P+ G +T
Sbjct: 17184 IVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPIT 17243
Query: 1810 TLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYT 1869
+ V PR + +T + + T F+++A P ++ D
Sbjct: 17244 AKDEVELPRISMDPKFRDTIVVNAGET-------FRLEADVHGKPLPTIEWLRGDKEIEE 17296
Query: 1870 ITGLQ-PGTDYKIYL------------YTLNDN----ARSSPV---VIDASTAIDAPSNL 1909
+ TD+K L Y L + ++S PV V+D + P +
Sbjct: 17297 SARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGP--V 17354
Query: 1910 RFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEP 1965
+ T ++W PP + I+ Y+++ ++ S V +T L
Sbjct: 17355 QVTGVTSEKCSLTWSPPLQDGGSDISHYVVE-KRETSRLAWTVVASEVVTNSLKVTKLLE 17413
Query: 1966 GTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTH 2025
G EY ++A+ EPL + P L+ P P+ L+V + + + V
Sbjct: 17414 GNEYVFRIMAVNKYGVGEPL------ESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCW 17467
Query: 2026 PGYDTGNGIQLPG 2038
D+ G ++ G
Sbjct: 17468 NRPDSDGGSEIIG 17480
Score = 94.0 bits (232), Expect = 2e-18
Identities = 154/662 (23%), Positives = 253/662 (38%), Gaps = 93/662 (14%)
Query: 1447 VSDVP---RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
V DVP R+LEV + ++W+ P I Y + + + + ++ +
Sbjct: 6714 VIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAES 6773
Query: 1504 ---TISGL-KPGVDYTITVYAVT--GRGDSPASSKPISINYRTEIDKPS-QMQVTDVQDN 1556
T++GL K GV+Y V A G G+ + P+ + ++ P + +TDV
Sbjct: 6774 CEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRF 6833
Query: 1557 SISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV 1612
+S+ W P + +T Y + K T + T+ + EY V
Sbjct: 6834 GVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRV 6893
Query: 1613 YAQNPSGESQPLVQTAVTN----IDRPK---GLAFTDVDVDSIKIAWESPQGQVSRYRVT 1665
AQN G +P T I+RP L +D S+++ WE P +
Sbjct: 6894 RAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILG 6953
Query: 1666 Y--SSPEDGIH-------ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIG 1716
Y E+G +L P E T ++ GL G++Y V A + S P
Sbjct: 6954 YIIERCEEGKDNWIRCNMKLVP-----ELTYKVTGLEKGNKYLYRVSAENKAGVSDP--- 7005
Query: 1717 TQSTAIPAPTDLKFTQVTPT-SLSA-----QWTPPN-----VQLTGY-RVRVT-----PK 1759
+ I P V PT LSA + PN V TGY R T
Sbjct: 7006 ---SEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKV 7062
Query: 1760 EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPP 1817
+TG ++ + +V+S + + + +Y LK + G V + S P
Sbjct: 7063 LETGDRVKMKTLSAYAELVISP---SERSDKGIYTLKLENRVKTISGEIDVNVIARPSAP 7119
Query: 1818 RRARVTDATETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGL 1873
+ + D T+ ++ ++W + +TG+ V+ + +T + +T+ L
Sbjct: 7120 KELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDL 7179
Query: 1874 QPGTDYKIYLYTLNDNARSSPVVIDA-------STAIDAPSNLRFLATTPNSLLVSWQPP 1926
G +Y + N P +D +T D P N+++ T NS+ ++W PP
Sbjct: 7180 VQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPP 7239
Query: 1927 R----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 1982
+ +RI GYI++ GS P T+ +TGLE G Y V AL S
Sbjct: 7240 KNDGGSRIKGYIVERCPRGSDKWVACGEP-VAETKMEVTGLEEGKWYAYRVKALNRQGAS 7298
Query: 1983 EPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQ 2042
+P + T+E+ + T P + LDV T G I+LP T
Sbjct: 7299 KP---SRPTEEIQAVDTQEAPEI----FLDVKLLAGLT-------VKAGTKIELPATVTG 7344
Query: 2043 QP 2044
+P
Sbjct: 7345 KP 7346
Score = 94.0 bits (232), Expect = 2e-18
Identities = 327/1598 (20%), Positives = 576/1598 (36%), Gaps = 255/1598 (15%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W+ P+ S I+ +I+ R + W++ I + I GL G Y+ ++I+
Sbjct: 8843 LNWSDPEDDGGSEITGFIIE-RKDAKMHTWRQP-IETERSKCDITGLLEGQEYKFRVIAK 8900
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV--- 741
++G PV + P + TE T S+ + W
Sbjct: 8901 NKFG-------------CGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPR 8947
Query: 742 -SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQS 800
+ + G+ +E ++ D + TS + +L + Y V ++E GE
Sbjct: 8948 SNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESE 9007
Query: 801 LILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWSRP---QAPITGYRIVYSPSVEGSST 854
L + D P PT+ V +I V+ P A +TG + P +E S
Sbjct: 9008 PSLPLNVVIQDDEVP-PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPM---PKIEWSKN 9063
Query: 855 E--LNLPETANSVTLSDLQPG-VQYNITI-YAVEENQESTPVVIQQETTGTPRS------ 904
E + P A +T ++ + ++I AV E++ + V R+
Sbjct: 9064 ETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVY 9123
Query: 905 DTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
D PR+L ++ + W P S +T Y +D + + + NT
Sbjct: 9124 DRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVT---NT 9180
Query: 961 FAE----VTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKLDAPTNL-QFVNETD 1010
E + L P Y F+V + +S +S + Q +L P + + T
Sbjct: 9181 AVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTK 9240
Query: 1011 STVLVRWTPP----RAQITGYRLTVGLTRRGQPRQY----------NVGPSVSKYPLRNL 1056
++LV WTPP + ITGY L +R + Y VG ++ + L
Sbjct: 9241 GSMLVSWTPPLDNGGSPITGY----WLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRL 9296
Query: 1057 QPASEYTVSLVAIKG------NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
+Y +AI ++ S PG P + T+++I + W P
Sbjct: 9297 LEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPP 9356
Query: 1111 PRIGFKLGVRPSQG--GEAPREVTSD------------SGSIVVSGLTPGVEYVYTIQVL 1156
K G P +G E E T+D + VV L +Y + ++ +
Sbjct: 9357 A----KDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAV 9412
Query: 1157 RD-GQERDAPIVNKV-VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT- 1213
+ G+ + ++ T + + ++ ++ + + P + R T +
Sbjct: 9413 NEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSW 9472
Query: 1214 --NGQQGNSLEEVVH---ADQSSCTFDNLSPGL----------EYNVSVYTVKDDKESVP 1258
+G+ ++++ VH D T +N S + +Y+++ K +++
Sbjct: 9473 EFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKN-KAGQKTAN 9531
Query: 1259 ISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEED-VAELSIS 1317
++ PP DL+ ++I + R++W P D + + Y K D A ++
Sbjct: 9532 CRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDD-DGGDRIKGYVIEKRTIDGKAWTKVN 9590
Query: 1318 P--SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL-------DSPTGIDFSD 1368
P V+ +LL +Y V + P+ Q+T D P +
Sbjct: 9591 PDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGL 9650
Query: 1369 ITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRED-RVPHSRN----SITLTNLT 1419
IT N+ + W P+ + +T Y + +G +E R + R+ T+ +L
Sbjct: 9651 ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLV 9710
Query: 1420 PGTEYVVSIVALN--GREESPLLIG-------QQSTVSDVPRDLEVVAATPTSLLIS-WD 1469
G EY + A+N G + +G D+ +EV T +++
Sbjct: 9711 EGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKG 9770
Query: 1470 APAVTVRYYRITYGETGGNSPVQEFT-----VPGSKSTATISGLKPGVDYTITVYAVTGR 1524
P T+ +++ + PV T V T I + T+ AV
Sbjct: 9771 VPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNL 9830
Query: 1525 GDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPK 1579
G +SK + +N P ++ V + +++ W P S +T Y +
Sbjct: 9831 G---TASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREA 9887
Query: 1580 NGPGPTKT---KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT--NI-- 1632
N KT ++ P + TI L EYV + AQN G +PL T N+
Sbjct: 9888 N----RKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFS 9943
Query: 1633 --DRPKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDT 1686
P + V +S+ + WE P+ V+ Y + +D + + + +
Sbjct: 9944 VPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGY---WLEMKDTTSKRWKRVNRDPIK 10000
Query: 1687 A-------ELQGLRPGSEYTVSVVALH------DDMESQPLIGTQSTAIPAPTDLKFTQV 1733
A ++ GL GS+Y V A++ + S P A P P K T
Sbjct: 10001 AMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDW 10060
Query: 1734 TPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 1789
T +S +W+PP ++TGY V + K K + + +VV+GL Y+
Sbjct: 10061 TKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYK 10120
Query: 1790 VSVYALKDTLTSRPAQGVVTTLEN----VSPPRR--ARVTD----------------ATE 1827
V A+ P + V +E VSP + A V D + +
Sbjct: 10121 FRVRAVNIAGIGEPGE-VTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGK 10179
Query: 1828 TTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDV--RSYTITGLQPGTDYKIYLYT 1885
T++W T+ P + TI+ S I Q L
Sbjct: 10180 PPPTVTWNMNERTL--------------PQEATIETTAISSSMVIKNCQRSHQGVYSLLA 10225
Query: 1886 LNDNARSSPVVIDASTAIDAPSNLRFLA--TTPNSLLVSWQPPR----ARITGYIIKYEK 1939
N+ +I + P FLA T S ++W P + IT Y+I EK
Sbjct: 10226 KNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVI--EK 10283
Query: 1940 PGSPPREVVPRPRPGVTE-ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLV 1998
S R P + AT+ GL G Y + IA +N+ P + + + + +
Sbjct: 10284 RESDRRAWTPVTYTVTRQNATVQGLIQGKAY-FFRIAAENSIGMGPFVETSEALVIREPI 10342
Query: 1999 TLPHPNLHGPEILDVPSTVQKTPFVT--HPGYDTGNGI 2034
T+P PE L+V + T +T P YD G+ I
Sbjct: 10343 TVP----ERPEDLEVKEVTKNTVTLTWNPPKYDGGSEI 10376
Score = 94.0 bits (232), Expect = 2e-18
Identities = 304/1555 (19%), Positives = 549/1555 (35%), Gaps = 206/1555 (13%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W P S I+ Y+L R +V K P + GL+ G YE ++ +I
Sbjct: 13134 VSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAI 13193
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW---- 740
+ G + + S + P V + T SS +SW
Sbjct: 13194 NKAGPGKPSD------------ASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPA 13241
Query: 741 VSASDTVSGFRVEYELSEEGDEPQYLDLPST--ATSVNIPDLLPGRKYIVNVYQISEDGE 798
+ G+ VE + + + D +LP T + L+ +Y VY +++ G
Sbjct: 13242 YDGGSPIIGYLVEVKRA-DSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIG- 13299
Query: 799 QSLILSTSQTTAPD--------APPDPTVDQVDDTSIVVR---WSRPQAPITGYRIVYSP 847
+ + PD PP+ +D ++++R R P+ G P
Sbjct: 13300 -----YSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRP---PP 13351
Query: 848 SVEGSSTELNLPETAN-SVTLSDLQPGV-----------QYNITIYAVEENQESTPVVIQ 895
+ S +NL + + +D + +Y +T+ +E T VV
Sbjct: 13352 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13411
Query: 896 QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHG 951
+T G P + TV E++ + W PP S + Y V
Sbjct: 13412 LDTPGPPVNVTVK--------EISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWST 13463
Query: 952 QRLPISRNTFAEVTGLSPGVTYYFKVFAVSH---GRESKPLTAQQTTKLDAP-TNLQFVN 1007
S+ +F V L G +Y+F+VFA + G + A + ++ P +L+ +
Sbjct: 13464 VTTECSKTSF-RVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRS 13522
Query: 1008 ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYT 1063
+ S+ + W P ++I GY + LT + ++ S+ +Y ++L EYT
Sbjct: 13523 VSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMKSLSL-QYSAKDLTEGKEYT 13580
Query: 1064 VSLVAIKGNQE-SPKATGVFT---TLQPG---SSIPPYNTEVTETT-----IVITWTPAP 1111
+ A N E +P V + P +P E + I I PAP
Sbjct: 13581 FRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAP 13640
Query: 1112 RIGFKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
+ +K G P + E ++ + +++V YTI + ++ I KV
Sbjct: 13641 SVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKV 13700
Query: 1171 VTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
V PT +T+ W + +IT Y + + + + V
Sbjct: 13701 VGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAV-- 13758
Query: 1228 DQSSCTFDNLSPGLEYNVSV-----YTVKDDKESVPI---SDTIIPAVPPPTDLRFTNIG 1279
+++ L G+EY V Y V + +S PI +P PPP ++ ++
Sbjct: 13759 QKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNI--VDVR 13816
Query: 1280 PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVA-----ELSISPSDNAVVLTNLLPGTEY 1334
D++ +TW P + + K + + I D V T L G EY
Sbjct: 13817 HDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV--TGLTEGLEY 13874
Query: 1335 VVSVSSVYEQHESTPLRGRQKT----GLDSPTGIDFSDITANSFTVHWIAPR----ATIT 1386
V ++ P + +D P + +IT NS T+ W P+ +T
Sbjct: 13875 EFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLT 13934
Query: 1387 GYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN--GREESPLLIGQQ 1444
GY + + + V + T+T+L G +Y I A N G +P +
Sbjct: 13935 GYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAP----SE 13990
Query: 1445 STVSDVPRDLEVVAATPTSLLISWDAPAVTVR----------------YYRITYGETGGN 1488
ST + + +D PT +L +T++ + ++ + G +
Sbjct: 13991 STETIICKD---EYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKD 14047
Query: 1489 SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQM 1548
+ T S T+++ +K Y +T + + + P +
Sbjct: 14048 IRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPV 14107
Query: 1549 QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
++++V ++ W P SP+ Y + + T + + +Q
Sbjct: 14108 EISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQG 14167
Query: 1605 TVEYVVSVYAQNPSGESQPLVQTAVTNIDR------PKGLAFTDVDVDSIKIAWESP--- 1655
EY+ V A N G+ +P+ V +DR P+ ++V ++ ++W+ P
Sbjct: 14168 N-EYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDD 14226
Query: 1656 -QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVA-----LHDDM 1709
+++ Y V + + ++ GL+ GS Y V A +
Sbjct: 14227 GGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPS 14286
Query: 1710 ESQPLIGTQSTAIP--APTDLKFTQVTPTSLSAQWTPPN----VQLTGYRVRVTPKEKTG 1763
E+ + + A P P++ T T S S W P+ +++TGY V +K G
Sbjct: 14287 EASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGY---VVEHQKVG 14343
Query: 1764 PMKEI----NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRR 1819
I A + VV L KY + A+ D PA V+ +E V
Sbjct: 14344 DEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPA--VIPDVEIVEREMA 14401
Query: 1820 ARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIK-------PDVRSYTITG 1872
E T+ R + PA T + I + S+T+
Sbjct: 14402 PDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTLLI 14461
Query: 1873 LQPGTDYKI--YLYTLNDNARSSPVVIDASTAIDAPS---NLRFLATTPNSLLVSWQPP- 1926
+ Y ++ T+ + A ++ +D P NLR T +S+ + W P
Sbjct: 14462 IPECNRYDTGKFVMTIENPAGKKSGFVNV-RVLDTPGPVLNLRPTDITKDSVTLHWDLPL 14520
Query: 1927 ---RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 1983
+RIT YI++ ++ + + +TGL G EY V+A E
Sbjct: 14521 IDGGSRITNYIVE-KREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGE 14579
Query: 1984 PLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPG 2038
P +T E + P P P+ L++ + T + P G ++ G
Sbjct: 14580 P----TETTEPVKASEAPSP----PDSLNIMDITKSTVSLAWPKPKHDGGSKITG 14626
Score = 93.6 bits (231), Expect = 2e-18
Identities = 287/1440 (19%), Positives = 522/1440 (36%), Gaps = 175/1440 (12%)
Query: 675 VVYEGQLISIQQYGHQEVTRFDFTTTSTS--TPVTSNTVTGETT--PFSPLVATSESVTE 730
+ E I++++ + R++ T ++S T N V + P P+V +++
Sbjct: 20155 ITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVV-----ISD 20209
Query: 731 ITASSFVVSWVSAS-DTVSGFRVEYELSEEGDEPQYLDLPSTA--TSVNIPDLLPGRKY- 786
IT S + W D S L E + ++ +T T + + L G +Y
Sbjct: 20210 ITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQ 20269
Query: 787 ----IVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYR 842
N + IS+ + + + T P P P V V SI V W P + G
Sbjct: 20270 FRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVS--NGGS 20327
Query: 843 IVYSPSVEGSSTELNLPETANSVTL-------SDLQPGVQYNITIYAVEENQESTPVVIQ 895
V +E L + AN + + + + G+ Y +YA P
Sbjct: 20328 AVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKP---S 20384
Query: 896 QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHG 951
+ D PR+++ +++ V++ W P S +TGY V+ +LP
Sbjct: 20385 HPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVE--RRDLPDGRW 20442
Query: 952 QRLPISRNTFAE--VTGLSPGVTYYFKVFAVSH-GRESKPL-TAQQTTKLDAPTNLQFVN 1007
+ + T + ++GL+ Y F+VFA + G S P T +D+
Sbjct: 20443 TKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDL 20502
Query: 1008 ETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--RQYNVGPSVSKYPLRNLQPASEYTVS 1065
+ T +V++ T +L G++ + P Y + L ++ ++
Sbjct: 20503 PLEYTEVVKYRAG----TSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASI 20558
Query: 1066 LV-------------AIKGNQESPKATGVFTTL-QPGSSIPPYNTE-VTETTIVITW-TP 1109
L+ ++ S AT L +PG P + VT I + W P
Sbjct: 20559 LIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPP 20618
Query: 1110 APRIGFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQVLR-----D 1158
A G K+ + E R V S + I + + G EY++ ++ + +
Sbjct: 20619 ADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGE 20678
Query: 1159 GQERDAPIV-NKVVTPLSP--PTNLHLEANPDTGVLTVSWERSTT---PDITGYRITTTP 1212
E D+ + N VTP P P + N +TV W R DI+GY +
Sbjct: 20679 PLESDSVVAKNAFVTPGPPGIPEVTKITKNS----MTVVWSRPIADGGSDISGYFLEKRD 20734
Query: 1213 TNGQQG-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV--------KDDKESVPISDTI 1263
L+E + + T L+ +Y V V + E +D I
Sbjct: 20735 KKSLGWFKVLKETIRDTRQKVT--GLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPI 20792
Query: 1264 IPAVPPPTDLRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEE-DVAELSISPS 1319
P PP +R + ++ + W+ P +T ++V + EE
Sbjct: 20793 DPP-GPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVR 20851
Query: 1320 DNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ----KTGLDSPTGIDFSDITANSFT 1375
V++NL PG Y VS+V + P+ + K L++P ID S
Sbjct: 20852 TTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPE-IDLDVALRTSVI 20910
Query: 1376 VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSI---------TLTNLTPGT--EY 1424
+ ++ R P + ++ +R SI T+ +T +Y
Sbjct: 20911 AKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKY 20970
Query: 1425 VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1484
+++I G +S + + + L+V + ++ + WD P + I Y
Sbjct: 20971 ILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 21030
Query: 1485 TGGNSPVQEFTVPGSKSTATISGL-----KPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
++ + ++V K ++T L K + + G G+ +++P+
Sbjct: 21031 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVK---A 21087
Query: 1540 TEIDKP-SQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594
E+ P + + D S+ + W S +T Y V + G G AG +
Sbjct: 21088 AEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVV---ERKGKGEQTWSHAGISK 21144
Query: 1595 T-EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFT-DVDVDSIKIAW 1652
T E+ + L+ V+A+N G S P+ +T K L T +VD+ I A
Sbjct: 21145 TCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPIT----VKELIITPEVDLSDIPGAQ 21200
Query: 1653 ESPQ-GQVSRYRVTY-SSPEDGIHEL---FPAPDGE-------EDTAELQGLRPGSEYTV 1700
+ + G + Y P+ I L P + E E+ L E+
Sbjct: 21201 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGG 21260
Query: 1701 SVVALHDDMESQPLIGTQSTAIPAPT----DLKFTQVTPTSLSAQWTPP----NVQLTGY 1752
+ D+ + + + P+ ++F ++ S+ W P ++T Y
Sbjct: 21261 KYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCY 21320
Query: 1753 RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLE 1812
+ +T K + + ++ V L+ +Y+ V A S+P + +
Sbjct: 21321 SIEKRETSQTN-WKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAK 21379
Query: 1813 N----VSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKP- 1863
+ PP + + + T ++++W +TGF V+ N + P
Sbjct: 21380 HQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPI 21439
Query: 1864 DVRSYTITGLQPGTDYKIYLYTLNDNARSSP----VVIDASTAIDAPSNLRFLATTPNSL 1919
R Y TGL G DY+ +Y N SSP A + +D P ++ T ++
Sbjct: 21440 SGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETI 21499
Query: 1920 LVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 1975
+ W PP ++I GY I+ ++ G+ + T+TGL PG Y +IA
Sbjct: 21500 TLKWNPPLRDGGSKIVGYSIE-KRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIA 21558
Score = 91.3 bits (225), Expect = 1e-17
Identities = 329/1588 (20%), Positives = 528/1588 (33%), Gaps = 253/1588 (15%)
Query: 589 CYGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPK 648
C R GE+ S + V + + + P P PI P H++ + W+P
Sbjct: 11201 CLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTG-PINILDVTPEHMT---ISWQPP 11256
Query: 649 NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQL-----ISIQQYGHQEVTRFDFTTTSTS 703
G I + + GVV G I Q G + V R
Sbjct: 11257 KDDGG--SPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGV 11314
Query: 704 TPVTSNTVTGETTPFSPLVATSESV-TEITASSFVVSWV----SASDTVSGFRVEYELSE 758
P +T T FSP + V T+IT ++ VSW ++G+ +E
Sbjct: 11315 GPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERR-EV 11373
Query: 759 EGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTA--PDAPPD 816
G + P + L G Y V+ + G S+ A P PP
Sbjct: 11374 TGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPG 11433
Query: 817 PTV-----DQVDDTSIVVRWSRPQA----PITGYRIVYSPSVEGSSTELNLPETANSVT- 866
P + D+ +T+ +V W++P + PI GY + +N E
Sbjct: 11434 PPINPKLKDKSRETADLV-WTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQCAF 11492
Query: 867 -LSDLQPGVQYNITIYAVE-----ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTD 920
+ L G +Y I A E +E VI ++ P + + RD+ V V
Sbjct: 11493 RVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRVGQ 11552
Query: 921 V-----------KVTIMWTPPESA-VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLS 968
+ I WT V RVD+I Q LP E
Sbjct: 11553 TIRILARVKGRPEPDITWTKEGKVLVREKRVDLI---------QDLPRVELQIKEAVRAD 11603
Query: 969 PGVTYYFKVFAVSHGRESKPLTAQQTTKLDAP---TNLQFVNETDSTVLVRWTPPRAQIT 1025
G + H + S + LD P NL+ N T + W P
Sbjct: 11604 HGKYIISAKNSSGHAQGSAIVNV-----LDRPGPCQNLKVTNVTKENCTISWENPLDN-G 11657
Query: 1026 GYRLTVGLTRRGQPRQYN---VGPSVSKYPLR-NLQPASEYTVSLVAIKGNQESPKATGV 1081
G +T + +P Q V V+K ++ NL +EY + A GV
Sbjct: 11658 GSEITNFIVEYRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCA-------ENKVGV 11710
Query: 1082 FTTLQPGSSI----------PPYNTEVTE---TTIVITWTP------APRIGFKLG--VR 1120
T++ + I P N + + T + + W +P + + + ++
Sbjct: 11711 GPTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLK 11770
Query: 1121 PSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP---LSPP 1177
S E + + +V Y + +Q +G E D +VV P
Sbjct: 11771 GSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPV 11830
Query: 1178 TNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNL 1237
+L L +GVLTV G I G +G EV T
Sbjct: 11831 LDLKL-----SGVLTVK---------AGDTIRLEA--GVRGKPFPEVAWTKDKDATDLTR 11874
Query: 1238 SPGLEYNVSVYTVKDDKESVPISD---------------------TIIPAVPPPTDLRFT 1276
SP ++ + + K SD ++ P +L+
Sbjct: 11875 SPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIV 11934
Query: 1277 NIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTE 1333
++ D V W PP ++ N+++ K + S + +T L+ G E
Sbjct: 11935 DVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMV-WSTYSATVLTPGTTVTRLIEGNE 11993
Query: 1334 YVVSVSSVYEQHESTPLRGRQ---KTGLDSPTGIDFSDITANS---FTVHWIAPR----A 1383
Y+ V + + P + KT D P D ++T S TV W P
Sbjct: 11994 YIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGK 12053
Query: 1384 TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN-------GREE 1436
+ITGY + +H + ++ + + NL P EY + A N
Sbjct: 12054 SITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPS 12113
Query: 1437 SPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP-----AVTVRYYRITYGETGGNSPV 1491
P++ P + VV T S+ + W P A + Y + SP
Sbjct: 12114 RPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPD 12173
Query: 1492 QEFTVPGS-----KSTATISGLKPGVDYTITVYAVTGRG-DSPASSKPISINYRTEIDKP 1545
+ + + + T++ L +Y V A G PA K E KP
Sbjct: 12174 EGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELK--------EAIKP 12225
Query: 1546 SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKT-KTAGPDQTEMTIE-GLQ 1603
++ D S++ L R+ + P P T + G D + L
Sbjct: 12226 KEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLV 12285
Query: 1604 PTVEYVV------------SVYAQNPSGESQPLVQTAVTNIDRP-KGLAFTDVDVDSIKI 1650
T+ ++V S+ NP+GE V V + P L +DV S +
Sbjct: 12286 DTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHV 12345
Query: 1651 AWESPQG----QVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH 1706
+W P+ QV+ Y V + P+ ++ + + L PG+EY V A++
Sbjct: 12346 SWAPPENDGGSQVTHYIVEKREADRKTWSTV-TPEVKKTSFHVTNLVPGNEYYFRVTAVN 12404
Query: 1707 D-------DMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP--------NVQLTG 1751
+ D+ L + P L+ T++T S + W PP + +T
Sbjct: 12405 EYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITS 12464
Query: 1752 YRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP--AQGVVT 1809
YR P ++ E ++ D S +VV+GL KY+ V A S P A+GV
Sbjct: 12465 YREEEQPADR---WTEYSVVKDLS-LVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYE 12520
Query: 1810 TLENVSPPRRARVTDAT---------------ETTITISWRT-KTETITGFQVDAVPANG 1853
E + PP+ T + T W+ + E +T + A+
Sbjct: 12521 AKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADS 12580
Query: 1854 QTP--IQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRF 1911
+ I+ + D Y++T D + VV+DA P ++
Sbjct: 12581 SSILIIKDVTRKDSGYYSLTAENSSG---------TDTQKIKVVVMDAPGPPQPPFDISD 12631
Query: 1912 LATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGT 1967
+ SL SW P + IT YI++ + S V T + L PG
Sbjct: 12632 IDADACSL--SWHIPLEDGGSNITNYIVE-KCDVSRGDWVTALASVTKTSCRVGKLIPGQ 12688
Query: 1968 EYTIYVIALKNNQKSEPLIGRKKTDELP 1995
EY V A SEPL K + P
Sbjct: 12689 EYIFRVRAENRFGISEPLTSPKMVAQFP 12716
Score = 90.9 bits (224), Expect = 1e-17
Identities = 273/1318 (20%), Positives = 459/1318 (34%), Gaps = 189/1318 (14%)
Query: 771 TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP---DPTVDQVDDTSI 827
++TS + DL + V +E G +T A + P D ++ TS+
Sbjct: 21048 SSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSV 21107
Query: 828 VVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAV 883
++ W++P + IT Y + E + + + +T + +S L+ ++A
Sbjct: 21108 ILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTCE-IEVSQLKEQSVLEFRVFAK 21166
Query: 884 EENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIP 943
E S PV I T + + +P ++ ++ +VT+ Y+ P
Sbjct: 21167 NEKGLSDPVTIGPITV----KELIITP-EVDLSDIPGAQVTVRIGHNVHLELPYKGKPKP 21221
Query: 944 VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN- 1002
+ G LP+ + F + +T K HG + + ++ P
Sbjct: 21222 SISWLKDG--LPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITV 21279
Query: 1003 ------------LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP 1046
++F +V++ W P +IT Y + T + +
Sbjct: 21280 ITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSV 21339
Query: 1047 SVSKYPLRNLQPASEYTVSLVAI-KGNQESPKATGVFTTLQ----PGSSIPPYNTEVTET 1101
+ + + + NL +EY + A + P + + PG P VT
Sbjct: 21340 ARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSD 21399
Query: 1102 TIVITWTP------APRIGFKLGVRPSQGGEAPREVTSD-SG-SIVVSGLTPGVEYVYTI 1153
+ +TW + GF + + + TS SG +GL G++Y + +
Sbjct: 21400 GMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRV 21459
Query: 1154 QVLRDG---QERDAPIVNKVVTPLSPP-TNLHLEANPDTGVLTVSWE---RSTTPDITGY 1206
D V+P+ PP T +++ +T +T+ W R I GY
Sbjct: 21460 YAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRET--ITLKWNPPLRDGGSKIVGY 21517
Query: 1207 RITTTPTNGQQGNSL-EEVVHADQSSC--TFDNLSPGLEYNV------SVYTVKDDKESV 1257
I +QGN D S C T LSPG Y +V T+ +S
Sbjct: 21518 SIEK-----RQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSS 21572
Query: 1258 PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAEL 1314
I T VPP GP+ LV+ PV +D E+
Sbjct: 21573 GIIMTRDENVPP-----IVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEI 21627
Query: 1315 SISPSDNAVVLTNLLPGTEYVV--------SVSSVYEQHESTPLRGRQKTGLDSPTG--- 1363
+ + +T++L T V V +V ++ S + K + G
Sbjct: 21628 EKRMN---MEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVV 21684
Query: 1364 --IDFSDITANSFTVHWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLT 1416
I F++IT T+ W AP A IT Y I + + ED+ S T
Sbjct: 21685 GPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC--EAQSYTAI 21742
Query: 1417 NLTPGTEYVVSIVALN----GR--EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
L G EY + A+N GR + P++ Q TV D P E T S+ ++W
Sbjct: 21743 KLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWAR 21802
Query: 1471 PAVTVRYYRITYGETGGNSPVQEFTV-----------------PGSKSTATISGLKPGVD 1513
P E+ G S +Q++ + P S++ ++GL G +
Sbjct: 21803 P------------ESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNE 21850
Query: 1514 YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ---MQVTDVQDNSISVKW----LPSS 1566
Y V A G PAS I R ++ P ++VTD ++S++W
Sbjct: 21851 YEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGG 21910
Query: 1567 SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ 1626
+ GY + + K +T T+ LQ EY V A N +G+
Sbjct: 21911 MEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEV 21970
Query: 1627 TA-VTNIDRPKGLAFTDVDVDS-IKIAWESPQGQVSRYRVTY----------SSPEDGIH 1674
T + +DR L ++D+D+ K G R + Y S P+ +
Sbjct: 21971 TGTIKAVDR---LTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLS 22027
Query: 1675 ---ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFT 1731
++ T E +YT++V + T P P + F
Sbjct: 22028 LRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP-PGPITFK 22086
Query: 1732 QVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE----INLAPDSSSVVVSGLMVATK 1787
VT S + W P + G R+ EK + I+ V+ L
Sbjct: 22087 DVTRGSATLMWDAPLLD-GGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVP 22145
Query: 1788 YEVSVYALKDTLTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISW----RTKTETI 1841
Y V A+ + P + + E +PPRR V D ++++ ++W I
Sbjct: 22146 YYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRI 22205
Query: 1842 TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1901
TG+ ++ ++ + ++T+ L T+Y+ + ND S P +S
Sbjct: 22206 TGYLLEMRQKGSDFWVEAGHTKQL-TFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSV 22264
Query: 1902 AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP---RPRPGVT 1956
I P P + L IT +I K GSP VP RP P VT
Sbjct: 22265 IIKEPQ------IEPTADLTG-------ITNQLITC-KAGSPFTIDVPISGRPAPKVT 22308
Score = 90.1 bits (222), Expect = 2e-17
Identities = 343/1758 (19%), Positives = 611/1758 (34%), Gaps = 294/1758 (16%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W P S I YI+ R + + W S + L G Y +++++
Sbjct: 16284 LAWKPPLQDGGSDIINYIVERRETSRLV-WTVVDANVQTLSCKVTKLLEGNEYTFRIMAV 16342
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVS-A 743
+YG E P+ S V + P + VT +T S +V W A
Sbjct: 16343 NKYGVGE-------------PLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPA 16389
Query: 744 SD---TVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKY-----IVNVYQISE 795
SD + G+ +E E + + + L+ Y N +SE
Sbjct: 16390 SDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSE 16449
Query: 796 DGEQSLILSTSQTTAPDAPPD-PTVDQVDDTSIVVRWSRP----QAPITGYRIVYSPSVE 850
S PP+ P V + +S+ + WS+P I GY +
Sbjct: 16450 PSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSV 16509
Query: 851 GSSTELNLPETAN--SVTLSDLQPGVQYNITIYAVE-----ENQESTPVVIQQETTGTPR 903
G T P N ++ + L +YN I A+ E+ + +I +E P
Sbjct: 16510 GEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPD 16569
Query: 904 SDTVPSPRDLQFVEVTDVK--------VTIMWTP-PE---SAVTGYRVDVIPVNLPGEHG 951
D DL+ ++ +++ V I P PE V G D +++
Sbjct: 16570 IDL-----DLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFT 16624
Query: 952 QRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDS 1011
+ + N + Y S G +S +T + P NL+ T
Sbjct: 16625 SLVLDNVNRYDSGK--------YTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKD 16676
Query: 1012 TVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLV 1067
+V + W PP ++I Y + R + + + LQ Y +
Sbjct: 16677 SVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVT 16736
Query: 1068 A-----IKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIG------FK 1116
A I ++ V QP I +VT ++ ++WT G +
Sbjct: 16737 AENEYGIGLPAQTADPIKVAEVPQPPGKITV--DDVTRNSVSLSWTKPEHDGGSKIIQYI 16794
Query: 1117 LGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERD-----APIVNK-- 1169
+ ++ + S V++ LT G EY++ + + + D PIV K
Sbjct: 16795 VEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDL 16854
Query: 1170 VVTPLSPP--TNLHLEANPDTGVL---------TVSWERSTTPDITGYRITTTPTNGQQG 1218
V+ P P ++ ++ D + T++W + P RI T +
Sbjct: 16855 VIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTT 16914
Query: 1219 NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNI 1278
S++E H D G +Y ++V V K + T+ PP ++F ++
Sbjct: 16915 LSIKET-HKDD----------GGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDV 16963
Query: 1279 GPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEE-DVAELSISPSDNAVVLTNLLPGTEY 1334
+++ ++W PP +TN++V+ DV +++ + + +T L GTEY
Sbjct: 16964 SAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVART--TLKVTKLKTGTEY 17021
Query: 1335 VVSV--SSVYEQH---ESTPLRGRQKTGLDSPTGIDFSD-ITANSFTVHWIAP----RAT 1384
+ + Y Q ES P+ + P G F+ I+ +S + W P +
Sbjct: 17022 QFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSP 17081
Query: 1385 ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQ 1444
+ GY + + + ++ NL G EY + A E+ + +G+
Sbjct: 17082 VIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYA-----ENIVGVGKA 17136
Query: 1445 STVSD--VPRDLEVVAATPTSLLISWDAPAVTVRYYRITY--GETGGNSPVQEFTVPGSK 1500
S S+ V RD TP +++ + +T+++ + Y G V++ +P +
Sbjct: 17137 SKNSECYVARDPCDPPGTPEPIMVKRNE--ITLQWTKPVYDGGSMITGYIVEKRDLPDGR 17194
Query: 1501 -----------STATISGLKPGVDYTITVYAVTGRGDSPASSKPIS----INYRTEIDKP 1545
+ T+SGL Y V A G A SKP I + E++ P
Sbjct: 17195 WMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAG---AISKPSDSTGPITAKDEVELP 17251
Query: 1546 SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPT 1605
+D + + +R+ P PT G + E +
Sbjct: 17252 RISMDPKFRDTIVV-------NAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKN 17304
Query: 1606 VEYVVSVY---------------AQNPSGESQPLVQTAVTNIDRPKG----LAFTDVDVD 1646
++ + A N +G V V +DRP + T V +
Sbjct: 17305 TDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKV--LDRPGPPEGPVQVTGVTSE 17362
Query: 1647 SIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSV 1702
+ W P +S Y V + A + ++ ++ L G+EY +
Sbjct: 17363 KCSLTWSPPLQDGGSDISHY-VVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRI 17421
Query: 1703 VALH-----DDMESQPLIGTQSTAIPAPT-DLKFTQVTPTSLSAQWTPPNV----QLTGY 1752
+A++ + +ES P++ +P P L+ T + S++ W P+ ++ GY
Sbjct: 17422 MAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGY 17481
Query: 1753 RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVV---- 1808
V + +K + V+GL +YE V A P+ V
Sbjct: 17482 IVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKA 17541
Query: 1809 -TTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKP 1863
+ PP A + D T+ +IT++W I G+ V+ A+ + + + P
Sbjct: 17542 CDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEE--WQIVTP 17599
Query: 1864 D----VRSYTITGLQPGTDYKIYLYTLN----DNARSSPVVIDASTAIDAPSNLRFLATT 1915
V + I+ L +YKI + LN A S P + ++AP L +
Sbjct: 17600 QTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAP-ELDLDSEL 17658
Query: 1916 PNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP---RPRPGVTEATITG-------LEP 1965
++V + G R +P RP P +T + G +E
Sbjct: 17659 RKGIVV-----------------RAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEK 17701
Query: 1966 GTEYT-------------IYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILD 2012
G YT Y++ L+N+ S+ K + P P NL E+
Sbjct: 17702 GVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPG----PPQNLAVKEVRK 17757
Query: 2013 VPSTVQKTPFVTHPGYDTGNGI----------------QLPGTSGQQPSVGQQMIF---- 2052
+ + P + G N + + TS + ++ + I+
Sbjct: 17758 DSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRV 17817
Query: 2053 -EEHGFRRTTPPTTATPIRHRPRPYPP-NVGQEALSQTTIS--W-APFQDTSE----YII 2103
E+ F P T ++ P PP V +SQT+ S W P D Y++
Sbjct: 17818 MAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVV 17877
Query: 2104 SCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSV 2163
P GT E +A +TGL+ G Y V+A ++ + R V+ V
Sbjct: 17878 EMQPKGT--EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPR--VLGVPVIA 17933
Query: 2164 NEGLNQPTDDSCFDPYTV 2181
+ QP+ F+ Y++
Sbjct: 17934 KDLTIQPSLKLPFNTYSI 17951
Score = 89.7 bits (221), Expect = 3e-17
Identities = 260/1286 (20%), Positives = 475/1286 (36%), Gaps = 231/1286 (17%)
Query: 780 LLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPIT 839
++P ++Y++ V ++ G + A D PT+D IV+ + P+
Sbjct: 7978 VVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVP 8037
Query: 840 GYRIVYSPSV----EGSSTELNLPETANSVTLS---DLQPGVQYNITIYAV--EENQEST 890
+R V P+V +G + + T + +S ++ V+ + IY + E S
Sbjct: 8038 -FRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSA 8096
Query: 891 PVVIQQETTGTPRSDTVPSP-RDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGE 949
I + G +P P +D++ ++T + W PPE G + V E
Sbjct: 8097 TASINVKVIG------LPGPCKDIKASDITKSSCKLTWEPPE--FDGGTPILHYVLERRE 8148
Query: 950 HGQR--LPI--SRNTFA-EVTGLSPGVTYYFKVFAVSH--GRE----SKPLTAQQTTKL- 997
G+R +P+ N + V L P Y+F+V AV+ G E P+ AQ +
Sbjct: 8149 AGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPP 8208
Query: 998 DAPTNLQFVNETDSTVLVRWTPPR----AQITGY---RLTVGLTRRGQPRQYNVGPSVSK 1050
D P +++ N T + + W PP ++I GY ++ G R + ++ V +
Sbjct: 8209 DPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLV--PILT 8266
Query: 1051 YPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
Y + L+ EY + A A G+ +P + PP T + A
Sbjct: 8267 YTAKGLEEGKEYQFRVRA-------ENAAGIS---EPSRATPP--------TKAVDPIDA 8308
Query: 1111 PRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVL--RDGQERDAPIVN 1168
P++ + + +G E + S SGS P + ++ V+ + ++R AP+V
Sbjct: 8309 PKVILRTSLEVKRGDEIALDA-SISGSPY-----PTITWIKDENVIVPEEIKKRAAPLVR 8362
Query: 1169 KVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHAD 1228
+ + L P T L++ N ++G S V
Sbjct: 8363 RRKGEVQEEEPFVL---PLTQRLSID-------------------NSKKGESQLRVR--- 8397
Query: 1229 QSSCTFDNLSPGLEYNVSVYTVKDDK--ESVPISDTIIPAVPPPTDLRFTNIGPDTMRVT 1286
D+L P ++ + + V++D P + +++ PP + F +I ++
Sbjct: 8398 ------DSLRP--DHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCK 8449
Query: 1287 WAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE 1346
W PP D + ++ Y+ K ++ P +V+T+ L +Y SV+ + E E
Sbjct: 8450 WEPPLD-DGGSEIINYTLEKKDKT------KPDSEWIVVTSTLRHCKY--SVTKLIEGKE 8500
Query: 1347 ------------------STPLRGRQKTGL-DSPTGIDFSDITANSFTVHWIAPR---AT 1384
S PL + G D+P D+T+NS V W P+ +
Sbjct: 8501 YLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSP 8560
Query: 1385 ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLL 1440
I GY + + + R ++ + + L G YV + A N G+ P
Sbjct: 8561 ILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPP-- 8618
Query: 1441 IGQQSTVSD--------VPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGN 1488
T D +PR V + T++ + W+ PA + Y + G N
Sbjct: 8619 -SDPKTAHDPISPPGPPIPR---VTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTN 8674
Query: 1489 SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEIDKPSQ 1547
+ T+ ++ G DY + V AV G+ P ++P+++ E +P
Sbjct: 8675 EWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQPVTV---AEPQEPPA 8731
Query: 1548 MQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTK--TKTAGP-DQTEMTIEGLQP 1604
+++ +SVK R+ P PTK TK G D+ + I+ +
Sbjct: 8732 VEL------DVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGT 8785
Query: 1605 TVEYVVS-----------VYAQNPSGESQPLVQTAVTNIDRP-KGLAFTDVDVDSIKIAW 1652
E ++ + A N G + V ++ P L + + W
Sbjct: 8786 KSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNW 8845
Query: 1653 ESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH-- 1706
P+ +++ + + + +H + E ++ GL G EY V+A +
Sbjct: 8846 SDPEDDGGSEITGFIIERKDAK--MHTWRQPIETERSKCDITGLLEGQEYKFRVIAKNKF 8903
Query: 1707 ---DDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTP 1758
+E P++ P +P L +T+ T ++++ W P + GY +
Sbjct: 8904 GCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRR 8963
Query: 1759 KEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPA--QGVVTTLENVSP 1816
+K + ++S +V L YE V A+ + S P+ VV + V P
Sbjct: 8964 HDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPP 9023
Query: 1817 PRRARVTDATETTIT-------------------ISWRTKTETITGFQVDAVPANGQTPI 1857
+ R++ +T I W +K ET+ DA+ +
Sbjct: 9024 TIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEW-SKNETVIEKPTDALQITKEEVS 9082
Query: 1858 QRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI-DAPSNLRFLATT- 1915
+ K ++ GT YT+ + R V + + D PS R LA T
Sbjct: 9083 RSEAKTELSIPKAVREDKGT------YTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTD 9136
Query: 1916 --PNSLLVSWQPP----RARITGYII 1935
S ++W P + IT Y+I
Sbjct: 9137 IKAESCYLTWDAPLDNGGSEITHYVI 9162
Score = 87.4 bits (215), Expect = 1e-16
Identities = 347/1579 (21%), Positives = 545/1579 (34%), Gaps = 257/1579 (16%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W +P+ S I+ Y++ R + W T + T++GL G Y ++ +
Sbjct: 10263 LTWFSPEDDGGSPITNYVIEKRESDRRA-WTPVTYTVTRQNATVQGLIQGKAYFFRIAAE 10321
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
G F TS + + T P P V E+T ++ ++W
Sbjct: 10322 NSIGMGP-----FVETSEALVIREPI----TVPERP---EDLEVKEVTKNTVTLTWNPPK 10369
Query: 745 DTVSGFRVEYELSEE--GDEPQYLDLPSTATS--VNIPDLLPGRKYIVNVYQISEDGEQS 800
+ Y L G E + S + L G Y V ++ G+
Sbjct: 10370 YDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGK 10429
Query: 801 LILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPE 860
T T D PT+ + +R A Y P V E ++ E
Sbjct: 10430 PSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 10489
Query: 861 TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET---TGTPRSDTVPSPRD----L 913
+ T P I A + VV++ T G + + V P +
Sbjct: 10490 --DDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPV 10547
Query: 914 QFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI---SRNTFAEVTG 966
F EVT + I W PP S +T Y ++ V +P+ S T +V+
Sbjct: 10548 SFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVG----KDVWMPVTSASAKTTCKVSK 10603
Query: 967 LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD------APTNLQFVNETDSTVLVRWTPP 1020
L G Y F++ A + S PL + D AP T + LV W P
Sbjct: 10604 LLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP 10663
Query: 1021 R---AQITGYRLTVGLTRRGQPRQYNVGP--SVSKYPLRNLQPASEYTVSLVA---IKGN 1072
IT Y L T + + P +K+ + +L +Y + A I
Sbjct: 10664 HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIG 10723
Query: 1073 QESPKATGVFTTLQPGSSIPPYNTEVTETT---IVITWTPAPR-------IGFKLGVRPS 1122
SP + VF PP N E +TT + +TW P PR +G+ + +
Sbjct: 10724 DPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQP-PRHDGGSKILGYIVEYQ-K 10781
Query: 1123 QGGEAPREVTSDSGSIV-----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP---L 1174
G E R S V+GL G Y + + + E D V + V L
Sbjct: 10782 VGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRL 10841
Query: 1175 SPPTNLHLEANP---------DTGVLT----------VSWERSTTPDITGYRITTTPTNG 1215
PP L L+AN DT L+ V+W++ T RI TP
Sbjct: 10842 EPP-ELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS 10900
Query: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRF 1275
+ + H D + +P VSV + DK PP DL
Sbjct: 10901 KL--EIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG------------PPRDLEV 10946
Query: 1276 TNIGPDTMRVTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332
+ I D+ +TW P +TN++V V + + + LS + + +L G
Sbjct: 10947 SEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ-WSPLSATSKKKSHFAKHLNEGN 11005
Query: 1333 EYVVSVSSVYEQHESTPLRGRQKT--GLDS------PTGIDFSDITANSFTVHWIAPR-- 1382
+Y+ V++ Q+ P K LD P + D+ ++ W P
Sbjct: 11006 QYLFRVAAE-NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRD 11064
Query: 1383 --ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREE 1436
+ ITGY + + E + V + +T L G Y + A N G +
Sbjct: 11065 GGSPITGYLVEYQEEGTQDWIKFKTVTNLE--CVVTGLQQGKTYRFRVKAENIVGLGLPD 11122
Query: 1437 SPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTV 1496
+ + I Q + VP +E+ L++ TVR+ I G P ++T
Sbjct: 11123 TTIPIECQEKL--VPPSVELDVKLIEGLVVK---AGTTVRFPAIIRGVP---VPTAKWTT 11174
Query: 1497 PGSK---------------STATISGL--KPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
GS+ S TI + +Y ITV + A SK ++++
Sbjct: 11175 DGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV-------SNAAGSKTVAVHL- 11226
Query: 1540 TEIDKPSQ----MQVTDVQDNSISVKWLP----SSSPVTGYRVTT--TPKNGPGPTKTKT 1589
T +D P + + DV +++ W P SPV Y V T K+ G +
Sbjct: 11227 TVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVV---S 11283
Query: 1590 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR------PKGLAFTDV 1643
+G +T++ I LQ EYV V A+N G PL T + P TD+
Sbjct: 11284 SGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDI 11343
Query: 1644 DVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQ----GLRPGSEYT 1699
++ ++W P+ Y + + + + A+L+ GL G+ Y
Sbjct: 11344 TENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVN-KTPIADLKFRVTGLYEGNTYE 11402
Query: 1700 VSVVALH------DDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPP----NVQ 1748
V A + S P+ + P P + K + + WT P
Sbjct: 11403 FRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSP 11462
Query: 1749 LTGYRVRVTPKEKTGPMKEINLAP--DSSSVVVSGLMVATKYEVSVYALKDTLTSRP--- 1803
+ GY V K T IN + V GL+ +Y + A P
Sbjct: 11463 ILGYVVE-CQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPREL 11521
Query: 1804 AQGVVTTLENVSPPR-------RARVTDATETTITISWRTK-------TETITG------ 1843
A+ V+ + + PP R +T TI I R K T T G
Sbjct: 11522 AESVIAK-DILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVRE 11580
Query: 1844 FQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI 1903
+VD + + +Q IK VR+ Y I + +A+ S +V +
Sbjct: 11581 KRVDLIQDLPRVELQ--IKEAVRA-------DHGKYIISAKNSSGHAQGSAIV----NVL 11627
Query: 1904 DAP---SNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVT 1956
D P NL+ T + +SW+ P + IT +I++Y KP +V VT
Sbjct: 11628 DRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIV---ASDVT 11684
Query: 1957 EATI-TGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPS 2015
+ I L EY V A +N P I K P L P PE L +
Sbjct: 11685 KRLIKANLLANNEYYFRVCA-ENKVGVGPTIETK----TPILAINPIDRPGEPENLHIAD 11739
Query: 2016 TVQKTPFV--THPGYDTGN 2032
+ ++ P YD G+
Sbjct: 11740 KGKTFVYLKWRRPDYDGGS 11758
Score = 85.5 bits (210), Expect = 6e-16
Identities = 330/1597 (20%), Positives = 570/1597 (35%), Gaps = 278/1597 (17%)
Query: 737 VVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQ 792
+++W D ++GF +E + ++ Q ++ + + +I LL G++Y V
Sbjct: 8842 LLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIE--TERSKCDITGLLEGQEYKFRVIA 8899
Query: 793 ISEDG-----EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQA----PITGYRI 843
++ G E IL+ P +P T + ++I + W P++ PI GY I
Sbjct: 8900 KNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYII 8959
Query: 844 VY----SPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTP-----VVI 894
P E + L P T S + +L Y + AV E ES P VVI
Sbjct: 8960 EKRRHDKPDFERVNKRL-CPTT--SFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVI 9016
Query: 895 QQETTG-------TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLP 947
Q + + R DT+ ++ E + + P VI
Sbjct: 9017 QDDEVPPTIKLRLSVRGDTIK----VKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTD 9072
Query: 948 GEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH----GRESKPLTAQQTTKLDAPTNL 1003
+ +SR+ + V + V+ G + + + + P NL
Sbjct: 9073 ALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNL 9132
Query: 1004 QFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV--SKYPLRNLQ 1057
+ + + W P ++IT Y + R + V + +Y + L
Sbjct: 9133 AVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLI 9192
Query: 1058 PASEYTVSLVAIKGNQESPKATGVFTTLQ-----PGSSIPPYNTEVTETTIVITWTP--- 1109
P +Y + A+ S + +Q PG P T+ +++++WTP
Sbjct: 9193 PNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLD 9252
Query: 1110 ---APRIGFKLGVRP------SQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVLR-- 1157
+P G+ L R S+ AP G V L GV+Y + +
Sbjct: 9253 NGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAA 9312
Query: 1158 ----DGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE---RSTTPDITGYRITT 1210
+ D + + P PP+ ++ + + ++ W+ + I GY +
Sbjct: 9313 GIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSI-SLGWKPPAKDGGSPIKGYIVEM 9371
Query: 1211 TP---TNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAV 1267
T+ ++ N ++++ + C NL +Y V V + ES P SDT
Sbjct: 9372 QEEGTTDWKRVNEPDKLITTCE--CVVPNLKELRKYRFRVKAVNEAGESEP-SDTT--GE 9426
Query: 1268 PPPTDLR-----FTNIGPDTMRVTWA-------------PPPS----IDLTNFLVRYSPV 1305
P TD++ F +IG V A P P D V
Sbjct: 9427 IPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGV 9486
Query: 1306 KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP-LRGRQKTGLDSPTGI 1364
+ + A+L + + + +++ S+++ + + T R + P +
Sbjct: 9487 HDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDL 9546
Query: 1365 DFSDITANSFTVHWIAPRAT----ITGYRIRHHPEHFSGRPREDRVPH-SRNSITLTNLT 1419
SDIT S + W P I GY I G+ P + + +L
Sbjct: 9547 KVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRT--IDGKAWTKVNPDCGSTTFVVPDLL 9604
Query: 1420 PGTEYVVSIVALNGREESPLLIGQQSTVS-------DVPRDLEVVAATPTSLLISWDAPA 1472
+Y + A N P + Q T + D P L++ T ++ +SW P
Sbjct: 9605 SEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPP- 9663
Query: 1473 VTVRYYRITYGETGGNSPVQEFTVP-------GSKSTA--------------TISGLKPG 1511
+ G SPV + V G+K A T+ L G
Sbjct: 9664 -----------KNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEG 9712
Query: 1512 VDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTG 1571
+Y V AV G S S+ P Q D+ SI +K T
Sbjct: 9713 GEYEFRVKAVNAAGVSKPSATV----------GPCDCQRPDMPP-SIDLKEFMEVEEGTN 9761
Query: 1572 YRVTTTPKNGPGPT----KTKTAGPDQTEMTIEGLQPTVEYV----VSVYAQNPSGESQP 1623
+ K P PT K PD E + V V Q+ ++
Sbjct: 9762 VNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGL 9821
Query: 1624 LVQTAVTNIDR---------------PKG-LAFTDVDVDSIKIAWESPQ----GQVSRYR 1663
TAV N+ P G + F V D + ++W P+ +++ Y
Sbjct: 9822 YTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYV 9881
Query: 1664 VTY--SSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVA-----LHDDMESQPLIG 1716
+ ++ + +H + + +E T + L G EY ++A + + ++S+P
Sbjct: 9882 IEKREANRKTWVHV---SSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETA 9938
Query: 1717 TQSTAIP-APTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPM-KEINL 1770
++P AP + VT S++ W P +TGY + + K+ T K +N
Sbjct: 9939 RNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEM--KDTTSKRWKRVNR 9996
Query: 1771 APDSS-----SVVVSGLMVATKYEVSVYALKD------TLTSRPAQGVVTTLENVSPPRR 1819
P + S V+GL+ + Y+ VYA+ +L S PA T + ++PP
Sbjct: 9997 DPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPA----TARDPIAPPGP 10052
Query: 1820 A--RVTDATETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRS--YTIT 1871
+VTD T+++ + W + +TG+ V+ G+ ++ +VR +T
Sbjct: 10053 PFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVE-YKEEGKEEWEKGKDKEVRGTKLVVT 10111
Query: 1872 GLQPGTDYKIYLYTLNDNARSSPV----VIDASTAIDAPSNLRFLATTPNSLLVSWQPPR 1927
GL+ G YK + +N P VI+ + +P +L+ A+ + ++V
Sbjct: 10112 GLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSP-DLQLDASVRDRIVVH-AGGV 10169
Query: 1928 ARITGYIIKYEKPGSPPREVV--PRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP- 1984
RI Y+ G PP V R EATI T + +KN Q+S
Sbjct: 10170 IRIIAYV-----SGKPPPTVTWNMNERTLPQEATIE-----TTAISSSMVIKNCQRSHQG 10219
Query: 1985 ---LIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQL----P 2037
L+ + + E + + + ++LDVP V TPF+ H T +L P
Sbjct: 10220 VYSLLAKNEAGERKKTIIV--------DVLDVPGPVG-TPFLAHNL--TNESCKLTWFSP 10268
Query: 2038 GTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQ----EALSQTTISWA 2093
G P + +I + RR P T T R G+ ++ +I
Sbjct: 10269 EDDGGSP-ITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMG 10327
Query: 2094 PFQDTSEYIISCHPVGTDEEPLQFRVPG-TSTSATLT 2129
PF +TSE ++ P+ E P V T + TLT
Sbjct: 10328 PFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLT 10364
Score = 85.5 bits (210), Expect = 6e-16
Identities = 343/1679 (20%), Positives = 586/1679 (34%), Gaps = 264/1679 (15%)
Query: 611 PVEVFITETPSQPNSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNS-Y 666
P V +T+T S ++W+ P I YI+ K +G W + + + Y
Sbjct: 21885 PTVVKVTDTSKTTVS--LEWSKPVFDGGMEIIGYIIEMC-KADLGDWHKVNAEACVKTRY 21941
Query: 667 TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
T+ L+ G Y+ ++ +I G + S T V T P + A +
Sbjct: 21942 TVTDLQAGEEYKFRVSAINGAGKGD---------SCEVTGTIKAVDRLTAPELDIDANFK 21992
Query: 727 SVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLP 782
+ A + + +++ + T + + LS D D ST T N
Sbjct: 21993 QTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADI-HTTDSFSTLTVENCNRNDA 22051
Query: 783 GRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----API 838
G KY + V S G +S+ + P P T V S + W P A I
Sbjct: 22052 G-KYTLTVENNS--GSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARI 22108
Query: 839 TGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898
Y + + S ++ T ++DL GV Y + AV E P + +
Sbjct: 22109 HHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPI 22168
Query: 899 TGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVN----LPGEH 950
T + PR L V+ + + W P+ S +TGY +++ + H
Sbjct: 22169 VATEQP---APPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGH 22225
Query: 951 GQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETD 1010
++L + E T Y F+V A + S+P A + + P
Sbjct: 22226 TKQLTFTVERLVEKT------EYEFRVKAKNDAGYSEPREAFSSVIIKEPQ--------- 22270
Query: 1011 STVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNV------GPSVSKYPLRNLQPASEYTV 1064
P A +TG + + G P +V P V+ + L ++ V
Sbjct: 22271 -------IEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVT-WKLEEMRLKETDRV 22322
Query: 1065 SLVAIKGN-----QESPKATG--VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIG--- 1114
S+ K ++S + F TL+ + + ++ T+V+ P P G
Sbjct: 22323 SITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSV-----TVVVIGRPGPVTGPIE 22377
Query: 1115 ----------FKLGVRPSQGGEAPREVTS------DSGS--------------IVVSGLT 1144
G P GG E+T+ +SG+ I V+ LT
Sbjct: 22378 VSSVSAESCVLSWG-EPKDGGGT--EITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLT 22434
Query: 1145 PGVEYVYTIQVL-RDGQER---DAPIV--NKVVTPLSP--PTNLHLEANPDTGVLTVSWE 1196
+EY + + R G + API+ + V P +P P H+ AN +++ WE
Sbjct: 22435 KYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSAN----AMSIRWE 22490
Query: 1197 RSTTPDITGYRITTTPTNGQQGNSL----EEVVHADQSSCTFDNLSPGLEYNVSVYTV-- 1250
G +I ++ N++ E V + + L GLEY Y +
Sbjct: 22491 EPYHDG--GSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNA 22548
Query: 1251 ----KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYS 1303
K + S PI V P T++ T+ + W+ P + +++
Sbjct: 22549 AGVSKASEASRPIMAQ--NPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERK 22606
Query: 1304 PVKNEEDVAELSIS---PSDNAVVLTNLLPGTEYVVSVSS------VYEQHEST-PLRGR 1353
PV D L + SDN +T L G Y V + + + EST P+ R
Sbjct: 22607 PVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCR 22666
Query: 1354 Q-----KTGLDSPTGIDFSDITANSFTVHWIA----PRATITGYRIRHHPEHFSGRPRED 1404
K LD+ D I A S V A P I + + +
Sbjct: 22667 DEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY 22726
Query: 1405 RVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRD---LEVVAATP 1461
+ I + + +Y +++ +G + +++ V D P L V T
Sbjct: 22727 TGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMV----KVLDSPGPCGKLTVSRVTQ 22782
Query: 1462 TSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT--ISGLKPGVDYT 1515
++W P + +Y + ET S + V G T + ++ L +Y
Sbjct: 22783 EKCTLAWSLPQEDGGAEITHYIVERRET---SRLNWVIVEGECPTLSYVVTRLIKNNEYI 22839
Query: 1516 ITVYAVTGRGDS-PASSKPISINYRTEIDKPSQM-QVTDVQDNSISVKWLPSSSP----V 1569
V AV G P S+PI I P + + I ++W S +
Sbjct: 22840 FRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEI 22899
Query: 1570 TGYRVTTTPKNGPGPTKT-KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628
+ Y V K T+ K T + + L +Y V A N +G S+P +
Sbjct: 22900 SNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASN 22959
Query: 1629 VTNIDRPK-------GLAFTDVDVDSIKIAWESPQGQVSRYRVTY-----SSPEDGIHEL 1676
+ P D SI +AW P V Y D + +
Sbjct: 22960 FISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRV 23019
Query: 1677 FPAPDGEEDTAELQGLRPGSEYTVSVVALH---------DDMESQPLIGTQSTAIPAPTD 1727
+ L+ G +Y+ V A++ E +P+ + + D
Sbjct: 23020 HTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADD 23079
Query: 1728 LKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTG---PMKEINLAPDSSSVVVSGLMV 1784
LK T S + V ++G V K G + I +S S+++ +
Sbjct: 23080 LKKTVTIRAGASLRLM---VSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKV- 23135
Query: 1785 ATKYEVSVYALKDTLTS--RPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT---- 1838
+Y+ Y ++ S + A +V + P +V + + ++TI+W T
Sbjct: 23136 -NRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGG 23194
Query: 1839 ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIY-----LYTLNDNARSS 1893
+ + V+ A + T K Y I+GL GT Y +Y + + +S
Sbjct: 23195 APVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETS 23254
Query: 1894 PVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVP 1949
V+ + + P+ L + T +++ ++W+ P +R+TGY+++ K G+ V
Sbjct: 23255 DAVLVSEVPL-VPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVV 23313
Query: 1950 RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPE 2009
+P V E T+T L G +Y + A SEP E VT+ +L
Sbjct: 23314 TLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEP-------RETVTAVTV--QDLRVLP 23364
Query: 2010 ILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPI 2069
+D+ + QKT V G ++L +P F R + T T
Sbjct: 23365 TIDLSTMPQKTIHV-----PAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHT 23419
Query: 2070 RHRPRPYPPNVGQEALSQTTISWAPFQDTSEYIISCHPV-GTDEEPLQFRV---PGTST 2124
+ V + + +TTI +DT EY + V GT E ++ + PG T
Sbjct: 23420 K---------VAKLTIRETTI-----RDTGEYTLELKNVTGTTSETIKVIILDKPGPPT 23464
Score = 84.3 bits (207), Expect = 1e-15
Identities = 258/1201 (21%), Positives = 430/1201 (35%), Gaps = 157/1201 (13%)
Query: 908 PSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS------RNTF 961
P L EVT K + W PP G ++D V RL + + T
Sbjct: 15185 PPEGPLAVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQK--RETSRLAWTNVASEVQVTK 15241
Query: 962 AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL------DAPTNLQFVNETDSTVLV 1015
+VT L G Y F+V AV+ +PL ++ + D P N + T +++V
Sbjct: 15242 LKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVV 15301
Query: 1016 RWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVS-----KYPLRNLQPASEYTVSLVAIK 1070
W P + + + RR + Q + + +Y + L EY ++A
Sbjct: 15302 CWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAEN 15361
Query: 1071 G-NQESPKATGVF-----TTLQPGSSIPPYNTEVTETT---IVITWTP------APRIGF 1115
+P T F T +PG PP N V +T+ I I W + G+
Sbjct: 15362 AAGISAPSPTSPFYKACDTVFKPG---PPGNPRVLDTSRSSISIAWNKPIYDGGSEITGY 15418
Query: 1116 KLGVRPSQGGEAPREVTSDSG----SIVVSGLTPGVEYVYTIQVLRD---GQERDAPIVN 1168
+ + + E + VT +G S ++GLT EY I + G+ P
Sbjct: 15419 MVEIALPEEDEW-QIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTP 15477
Query: 1169 KVVTPLSPPT-NLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
K + PP L + + R P I G G SL++
Sbjct: 15478 KAEDRMLPPEIELDADLRKVVTIRACCTLRLFVP-IKGRPAPEVKWARDHGESLDKASIE 15536
Query: 1228 DQSSCTFDNLSPGLEYNVSVY--TVKDDK--ESVPISDTIIPAVPPPTDLRFTNIGPDTM 1283
SS T + ++ Y TV++ +S ++ ++ PP DL+ + ++
Sbjct: 15537 STSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSV 15596
Query: 1284 RVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD---NAVVLTNLLPGTEYVVSVSS 1340
+TW PP +D + + Y K E S ++ + + L G Y V +
Sbjct: 15597 TLTW-DPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLA 15655
Query: 1341 VYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR----ATITGYRIRH 1392
E P + P I D+T NS ++ W P + I GY +
Sbjct: 15656 ENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEM 15715
Query: 1393 HPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPR 1452
+ V + T+T L G EY + A N E + +Q +V + +
Sbjct: 15716 QTKGSDKWATCATVKVTE--ATITGLIQGEEYSFRVSAQN---EKGISDPRQLSVPVIAK 15770
Query: 1453 DLEVVAA------TPTSLL---ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
DL + A T T L + D P + +T+ + N P+++ T ++ST
Sbjct: 15771 DLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKD--NVPLKQTTRVNAESTE 15828
Query: 1504 TISGL--KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ----MQVTDVQDNS 1557
S L K + Y V + + + +++ +DKP +++ +V +S
Sbjct: 15829 NNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNV---IVLDKPGPPTGPVKMDEVTADS 15885
Query: 1558 ISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG--LQPTVEYVVS 1611
I++ W P S + Y V K T + TI+ L+ EY
Sbjct: 15886 ITLSWGPPKYDGGSSINNYIVE---KRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFR 15942
Query: 1612 VYAQNPSGES-----QPLVQTAVTNIDRPKGLAFTDVDV-DSIKIAWESPQGQVSRYRVT 1665
+ A+N G+S +P V + P G + DS+++ W P +
Sbjct: 15943 IAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIG 16002
Query: 1666 YSSPEDGIHELF-------PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ 1718
Y + + P P + T GL G EY V A + +P ++
Sbjct: 16003 YHLERKERNSILWVKLNKTPIPQTKFKTT---GLEEGVEYEFRVSAENIVGIGKPSKVSE 16059
Query: 1719 STAIPAPTDL----KFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINL 1770
P D + VT S++ QW P ++TGY V + MK
Sbjct: 16060 CYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFT 16119
Query: 1771 APDSSSVVVSGLMVATKYEVSVYALKDT-LTSRPAQ--GVVTTLENVSPPRRARVTDATE 1827
+ V+GL+ +YE V A + S P++ G +T + V PPR + +
Sbjct: 16120 NIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKD 16179
Query: 1828 TTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ-PGTDYKIYLYTL 1886
T + + + F+VDA P + IK D L+ TD+ L ++
Sbjct: 16180 TIVVHAGES-------FKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSL-SV 16231
Query: 1887 NDNAR--SSPVVIDASTAIDAPS---NLRFL-------------ATTPNSLLVSWQPPR- 1927
D R S ++ A S N++ L T ++W+PP
Sbjct: 16232 KDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQ 16291
Query: 1928 ---ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
+ I YI++ + VV +T L G EYT ++A+ EP
Sbjct: 16292 DGGSDIINYIVERRETSRLVWTVVDA-NVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEP 16350
Query: 1985 L 1985
L
Sbjct: 16351 L 16351
Score = 83.6 bits (205), Expect = 2e-15
Identities = 268/1312 (20%), Positives = 473/1312 (36%), Gaps = 176/1312 (13%)
Query: 812 DAPPDPT----VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN 863
D P PT + + + S+ ++W P+ + +T Y ++ + TE++
Sbjct: 20196 DRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVART 20255
Query: 864 SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV-EVTDVK 922
+ + L G +Y I A EN+ I T P P +V VT
Sbjct: 20256 MMKVMKLTTGEEYQFRIKA--ENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRES 20313
Query: 923 VTIMWTPPES----AVTGYRVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
+T+ W P S AV GY +++ N + + +L I R T +VT +S G+ Y F+V
Sbjct: 20314 ITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVI-RTTHFKVTTISAGLIYEFRV 20372
Query: 978 FAVSHGRESKPL-TAQQTTKLDA---PTNLQFVNETDSTVLVRWTPPR----AQITGYRL 1029
+A + KP ++ +DA P N++ + + ++V + W P ++ITGY
Sbjct: 20373 YAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYI- 20431
Query: 1030 TVGLTRRGQP-----RQYNVGPSVSKYPLRNLQPASEYTVSLVA--IKGNQESP-KATGV 1081
+ RR P + + +++ + L S+Y + A G+ +P + G
Sbjct: 20432 ---VERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGP 20488
Query: 1082 FTTLQ----PGSSIPPYNTEVTE----TTIV----ITWTPAPRI-GFKLGVRPSQGGEAP 1128
T + P +P TEV + T++ I+ PAP I +K
Sbjct: 20489 ITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVC 20548
Query: 1129 REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
E T+D SI++ Y +++ A I +++ PP
Sbjct: 20549 VENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTA 20608
Query: 1189 GVLTVSWERSTTPD----ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
+T+ W R D IT Y + T+ + + E H ++ T + G EY
Sbjct: 20609 EKITLLW-RPPADDGGAKITHYIVEKRETSRVVWSMVSE--HLEECIITTTKIIKGNEYI 20665
Query: 1245 VSVYTVKDDKESVPI-SDTIIP-----AVPPPTDLRFTNIGPDTMRVTWAPP---PSIDL 1295
V V P+ SD+++ PP T I ++M V W+ P D+
Sbjct: 20666 FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDI 20725
Query: 1296 TNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY---VVSVSSVYEQHESTPLRG 1352
+ + + K+ L + D +T L ++Y V +V++ + S P
Sbjct: 20726 SGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEF 20785
Query: 1353 RQKTGLDSPTG----IDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPRED 1404
+ P G I +D T +S T+ W P + +TGY + E G E
Sbjct: 20786 YKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVV----EIRQGEEEEW 20841
Query: 1405 RVPHSRNSITLT-----NLTPGTEYVVSIVALN-GREESPLLIGQQSTVSDVPR----DL 1454
++ + T NL PG Y + A+N + P+ + + D+ DL
Sbjct: 20842 TTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDL 20901
Query: 1455 EVVAATPTSLLISWDA-----------PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
+V T D P VT R G S S S
Sbjct: 20902 DVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYS----IENTDSSSLL 20957
Query: 1504 TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISV 1560
TI + + G G+ +S+ + + +D P+ ++QV V ++++
Sbjct: 20958 TIPQVTRNDTGKYILTIENGVGEPKSSTVSVKV-----LDTPAACQKLQVKHVSRGTVTL 21012
Query: 1561 KWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGP-DQTEMTIEGLQPTVEYVVSVYAQ 1615
W P SP+ Y + ++ T + + T + L + V A+
Sbjct: 21013 LWDPPLIDGGSPIINYVI--EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAE 21070
Query: 1616 NPSGESQPLVQT---AVTNIDRP-KGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPED 1671
N G +P T + P + L+ D S+ ++W P Y
Sbjct: 21071 NEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERK 21130
Query: 1672 GIHELFPAPDGEEDTAELQ--GLRPGSEYTVSVVALHDDMESQPL-IGTQSTAIPAPTDL 1728
G E + G T E++ L+ S V A ++ S P+ IG P +
Sbjct: 21131 GKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIG--------PITV 21182
Query: 1729 KFTQVTP-TSLSAQWTPPNVQLT---GYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMV 1784
K +TP LS P Q+T G+ V + K P I+ D + S +
Sbjct: 21183 KELIITPEVDLS---DIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVR 21239
Query: 1785 ATKYEVSV-YALKDTLTSRPAQ------------GVVTTLENVSPPRR----ARVTDATE 1827
+K E + ++K+ + V T+ + PP + R +
Sbjct: 21240 FSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKA 21299
Query: 1828 TTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVR-SYTITGLQPGTDYKIY 1882
++ +SW + IT + ++ QT + R ++ + L +Y+
Sbjct: 21300 DSVILSWDVPEDNGGGEITCYSIEK-RETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFR 21358
Query: 1883 LYTLNDNARSSPVVIDASTA------IDAPSNLRFLATTPNSLLVSWQPP----RARITG 1932
+ N S P+V A P T + + ++W P + +TG
Sbjct: 21359 VRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTG 21418
Query: 1933 YIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
+ ++ ++ S + V E TGL G +Y V A + S P
Sbjct: 21419 FHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSP 21470
Score = 83.2 bits (204), Expect = 3e-15
Identities = 293/1378 (21%), Positives = 491/1378 (35%), Gaps = 236/1378 (17%)
Query: 811 PDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVT 866
P P + V + S + W P + IT Y I + S + E N+
Sbjct: 9126 PSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVI---DKRDASRKKAEWEEVTNTAV 9182
Query: 867 -----LSDLQPGVQYNITI-----YAVEENQESTPVVIQQ--ETTGTPRSDTVPSPRDLQ 914
+ L P QY + Y + + +S VVIQ G P V
Sbjct: 9183 EKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKV------- 9235
Query: 915 FVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLP-GEHGQRLPISR----NTFAEVT 965
+ T + + WTPP S +TGY ++ P R PI++ V
Sbjct: 9236 -LARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVP 9294
Query: 966 GLSPGVTYYFKVFAVSH---GRESKP----LTAQQTTKLDAPTNLQFVNETDSTVLVRWT 1018
L GV Y F+ A++ G S+P + P+ + ++T S++ + W
Sbjct: 9295 RLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWK 9354
Query: 1019 PPR----AQITGYRLTV---GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIK- 1070
PP + I GY + + G T + + + + + + NL+ +Y + A+
Sbjct: 9355 PPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVNE 9414
Query: 1071 -GNQESPKATG------------VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKL 1117
G E TG VF + + VI P P+ ++
Sbjct: 9415 AGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEF 9474
Query: 1118 GVRPSQG---------GEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVN 1168
+ + +A E +S I++ Y+I ++ A
Sbjct: 9475 DGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRV 9534
Query: 1169 KVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD------ITGYRITTTPTNGQQGNSLE 1222
KV+ PP +L + ++ G +SW+ PD I GY I +G+
Sbjct: 9535 KVMDVPGPPKDLKV-SDITRGSCRLSWKM---PDDDGGDRIKGYVIEKRTIDGKAWTK-- 9588
Query: 1223 EVVHADQSSCTF--DNLSPGLEYNVSV-----YTVKDDKESVPISDTIIPAVPP--PTDL 1273
V+ D S TF +L +Y V + + E++ + P PP P L
Sbjct: 9589 --VNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKL 9646
Query: 1274 RFTNIGPDTMRVTWAPPPS---IDLTNFLVR---YSPVK---------NEEDVAELSISP 1318
+ I +T+ ++W PP + +T+++V + P N+ DV EL +
Sbjct: 9647 KIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTV 9706
Query: 1319 SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL---DSPTGIDFSDI--TANS 1373
D L+ G EY V +V S P D P ID +
Sbjct: 9707 ED-------LVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEG 9759
Query: 1374 FTVHWIA-----PRATITGYRIRH----------HPEHFSGRPREDR----VPHSRNSIT 1414
V+ +A P T+T ++ + H + +D +P SR S T
Sbjct: 9760 TNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDT 9819
Query: 1415 LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP--- 1471
Y ++ V G + + ++ + + + +SW P
Sbjct: 9820 GL-------YTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDD 9872
Query: 1472 -AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG-DSPA 1529
+ Y I E + V + P + T TI L G +Y + A G P
Sbjct: 9873 GGSKITNYVIEKREANRKTWVHVSSEP-KECTYTIPKLLEGHEYVFRIMAQNKYGIGEPL 9931
Query: 1530 SSKPISI-NYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVT---TTPKN- 1580
S+P + N + P + V+ V NS++V W SPVTGY + TT K
Sbjct: 9932 DSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRW 9991
Query: 1581 ---GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG---ESQPLVQTAVTNIDR 1634
P K T G + GL +Y VYA N +G S P +
Sbjct: 9992 KRVNRDPIKAMTLG---VSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIA 10048
Query: 1635 PKGLAF---TDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTA 1687
P G F TD S + W P +V+ Y V Y E+G E D E
Sbjct: 10049 PPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYK--EEGKEEWEKGKDKEVRGT 10106
Query: 1688 EL--QGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPT-SLSAQWTP 1744
+L GL+ G+ Y V A++ +P G + I ++K V+P L A
Sbjct: 10107 KLVVTGLKEGAFYKFRVRAVNIAGIGEP--GEVTDVI----EMKDRLVSPDLQLDASVRD 10160
Query: 1745 PNVQLTGYRVRVT-------PKEKTGPMKEINLAPDSS--SVVVSGLMVATKYEVS---V 1792
V G +R+ P T M E L +++ + +S MV + S V
Sbjct: 10161 RIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGV 10220
Query: 1793 YAL--KDTLTSRPAQGVVTTLENVSPPRRARVT-DATETTITISWRTKTET----ITGFQ 1845
Y+L K+ R +V L+ P + + T + ++W + + IT +
Sbjct: 10221 YSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYV 10280
Query: 1846 VDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND-------NARSSPVV 1896
++ ++ + TP+ T+ ++ T+ GL G Y + N + V+
Sbjct: 10281 IEKRESDRRAWTPVTYTVTR--QNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVI 10338
Query: 1897 IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPR 1952
+ T + P +L T N++ ++W PP+ + I Y+++ G+ V
Sbjct: 10339 REPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDN 10398
Query: 1953 PGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVT----LPHPNLH 2006
+ T+ GL+ G Y V A+ ++G+ K + +T L P LH
Sbjct: 10399 LLSRKYTVKGLKEGDTYEYRVSAVN-------IVGQGKPSFCTKPITCKDELAPPTLH 10449
Score = 82.0 bits (201), Expect = 6e-15
Identities = 266/1310 (20%), Positives = 442/1310 (33%), Gaps = 219/1310 (16%)
Query: 731 ITASSFVVSWVSASDTVSGFRVEYELSE-EGDEPQYLDLPSTAT--SVNIPDLLPGRKYI 787
++A +SW D Y + + E + ++ + S + IP LL G +Y+
Sbjct: 9857 VSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYV 9916
Query: 788 V-----NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----API 838
N Y I E + + + + P AP PTV V S+ V W P+ +P+
Sbjct: 9917 FRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPV 9976
Query: 839 TGYRIVYSPSVEGSSTELNLPETANSVTL------SDLQPGVQYNITIYAVEENQESTPV 892
TGY + + +N + ++TL + L G Y +YA+ P
Sbjct: 9977 TGYWLEMKDTTSKRWKRVN-RDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVG-PA 10034
Query: 893 VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
+ + P P + + T + W+PP S VTGY V+
Sbjct: 10035 SLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEE 10094
Query: 949 EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGR-----------ESKPLTAQQTTKL 997
+ R T VTGL G Y F+V AV+ E K +L
Sbjct: 10095 WEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQL 10154
Query: 998 DAPTNLQFVNETDSTV----LVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSV--SKY 1051
DA + V + V PP +T + R P++ + + S
Sbjct: 10155 DASVRDRIVVHAGGVIRIIAYVSGKPPPT------VTWNMNERTLPQEATIETTAISSSM 10208
Query: 1052 PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT-EVTETTIVITWTP- 1109
++N Q + + SL+A E K V PG P+ +T + +TW
Sbjct: 10209 VIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSP 10268
Query: 1110 -----APRIGFKLGVRPS-QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD----- 1158
+P + + R S + P T + V GL G Y + I
Sbjct: 10269 EDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGP 10328
Query: 1159 -GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTN 1214
+ +A ++ + +T P +L ++ +T++W + +I Y + +
Sbjct: 10329 FVETSEALVIREPITVPERPEDLEVK-EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIG 10387
Query: 1215 GQQGNSLEEVVHADQSSCTFDNLSPG--LEYNVSVYTV----KDDKESVPISDTIIPAVP 1268
++ + + + T L G EY VS + K + PI T +
Sbjct: 10388 TEKFHKVTN-DNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPI--TCKDELA 10444
Query: 1269 PPT---------DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSI 1316
PPT +R T R + P P + S K+E DV E I
Sbjct: 10445 PPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKV---------SWFKDEADVLEDDRTHI 10495
Query: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP----TGIDFSDITAN 1372
+ + L + V E + Q +D P + F ++T +
Sbjct: 10496 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKD 10555
Query: 1373 SFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP----HSRNSITLTNLTPGTEYVVSI 1428
+ W P G +I ++ ++ +P ++ + ++ L G +Y+ I
Sbjct: 10556 YMVISW-KPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRI 10614
Query: 1429 VALNGREESPLLIG------QQSTVSDVPRDLEVVAATPTSLLISWDAP----------- 1471
A N S L+ + V D P V T S L++W+ P
Sbjct: 10615 HAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYI 10674
Query: 1472 -----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT--GR 1524
++ R+ R+T P +F VP L G Y V A G
Sbjct: 10675 LEKRETMSKRWARVTKDPI---HPYTKFRVP---------DLLEGCQYEFRVSAENEIGI 10722
Query: 1525 GDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRVTTT 1577
GD SKP+ + I KPS + D NS+ + W P S + GY +
Sbjct: 10723 GDPSPPSKPVFA--KDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGY-IVEY 10779
Query: 1578 PKNGPGPTKTKTAGPD---QTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LVQT 1627
K G + P+ +T+ + GL+ Y V A N +GES P LV+
Sbjct: 10780 QKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKD 10839
Query: 1628 AV--------TNIDRPKGLAFTDV--------DVDSIKIAWESPQGQVSRYRVTYSSPED 1671
+ N+ R + + D V K+ W+ +P
Sbjct: 10840 RLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVG 10899
Query: 1672 GIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFT 1731
E+ A + L P TVSV L D P DL+ +
Sbjct: 10900 SKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG------------PPRDLEVS 10947
Query: 1732 QVTPTSLSAQWTPP----NVQLTGYRVR-------------VTPKEKTGPMKEINLAPDS 1774
++ S W P +T Y V T K+K+ K +N
Sbjct: 10948 EIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLN----E 11003
Query: 1775 SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISW 1834
+ + + +Y + T +P + + L PP+ D +T +++ W
Sbjct: 11004 GNQYLFRVAAENQYGRGPF----VETPKPIK-ALDPLHPPGPPKDLHHVDVDKTEVSLVW 11058
Query: 1835 ----RTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYK 1880
R ITG+ V+ Q I+ ++ +TGLQ G Y+
Sbjct: 11059 NKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLEC-VVTGLQQGKTYR 11107
Score = 80.9 bits (198), Expect = 1e-14
Identities = 248/1194 (20%), Positives = 435/1194 (36%), Gaps = 142/1194 (11%)
Query: 908 PSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE 963
P +Q VT K ++ W+PP S ++ Y V+ + + N+ +
Sbjct: 17349 PPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSL-K 17407
Query: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA------PTNLQFVNETDSTVLVRW 1017
VT L G Y F++ AV+ +PL + + P +L+ N ++ V W
Sbjct: 17408 VTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCW 17467
Query: 1018 TPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQ---------PASEYTVSLVA 1068
P + G +G + R +K + +L+ E+ VS
Sbjct: 17468 NRPDSD--GGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAEN 17525
Query: 1069 IKGNQESPKATGVFTTLQPGSSI-PPYNTEVTETT---IVITWTP------APRIGFKLG 1118
G E AT + P PP N + +TT I + W + +G+ +
Sbjct: 17526 AAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVE 17585
Query: 1119 VRPSQGGEAPREVTSDSGSIV----VSGLTPGVEYVYTIQVLRD---GQERDAPIVNKVV 1171
+ + E + VT +G V +S LT EY + L G+ P K
Sbjct: 17586 ICKADEEEW-QIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPE 17644
Query: 1172 TPLSPPTNLHLEANPDTGVLT---------VSWERSTTPDITGYRITTTPTNGQQGNSLE 1222
L P L L++ G++ + ++ TP+IT R T+ Q +E
Sbjct: 17645 DKLEAP-ELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQ---IE 17700
Query: 1223 EVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDT 1282
+ V+ Q S + + +Y + + K + ++ ++ PP +L + D+
Sbjct: 17701 KGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAF-VTVKVLDTPGPPQNLAVKEVRKDS 17759
Query: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEED---VAELSISPSDNAVVLTNLLPGTEYVVSVS 1339
+ W PP ID + Y K E A +S S + + NL G Y V
Sbjct: 17760 AFLVWEPP-IIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVM 17818
Query: 1340 SVYEQHESTPLR---GRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIR 1391
+ E P+ + SP G + +D++ S ++ W P + + GY +
Sbjct: 17819 AENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE 17878
Query: 1392 HHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSIVALNGREES-PLLIGQQSTVSD 1449
P+ G + V S+ + +T L+ G EY + A N + +S P ++G D
Sbjct: 17879 MQPK---GTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKD 17935
Query: 1450 VPRDLEVVAATPTSLL-----ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT 1504
+ + T + + + P + I++ + G P+++ T + TAT
Sbjct: 17936 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDG--EPLKQTTRVNVEETAT 17993
Query: 1505 --ISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVK 1561
+ +K G Y VT + +++ +S+ + P ++ +V + + +
Sbjct: 17994 STVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVIS 18053
Query: 1562 WLPSS----SPVTGYRV-----TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV 1612
W P + ++ Y V TTT + T +T + I L+ EY +
Sbjct: 18054 WEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTT------IKITKLKTGTEYQFRI 18107
Query: 1613 YAQNPSGESQPLVQTAVT-----NIDRPKGLAF-TDVDVDSIKIAWESPQGQVSRYRVTY 1666
+A+N G+S PL AV P G F T + D + + W P + Y
Sbjct: 18108 FAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGY 18167
Query: 1667 SSPEDGIHELF-------PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQS 1719
+ + + P D + T GL G EY V A + +P ++
Sbjct: 18168 HLEQKEKNSILWVKLNKTPIQDTKFKTT---GLDEGLEYEFKVSAENIVGIGKPSKVSEC 18224
Query: 1720 TAIPAPTD----LKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLA 1771
P D + +T +++ +W P ++TGY V MK
Sbjct: 18225 FVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTN 18284
Query: 1772 PDSSSVVVSGLMVATKYEVSVYALKDTLT-SRP--AQGVVTTLENVSPPRRAR------- 1821
+ VSGL+ +YE V A S P + G +T + + P +
Sbjct: 18285 VLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDV 18344
Query: 1822 -VTDATET-TITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ-PGTD 1878
V A ET + R K + D +T + IK ++ T+ TD
Sbjct: 18345 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELE-ETAARMEIKSTIQKTTLVVKDCIRTD 18403
Query: 1879 YKIYLYTLND--NARSSPVVIDASTAIDAPSN-LRFLATTPNSLLVSWQPP----RARIT 1931
Y+ L++ +S P+ + P L+ T ++W PP A I+
Sbjct: 18404 GGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANIS 18463
Query: 1932 GYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 1985
YII+ + V + +T L PG EY V+A+ EPL
Sbjct: 18464 HYIIEKRETSRLSWTQVSTEVQAL-NYKVTKLLPGNEYIFRVMAVNKYGIGEPL 18516
Score = 78.6 bits (192), Expect = 7e-14
Identities = 278/1375 (20%), Positives = 475/1375 (34%), Gaps = 200/1375 (14%)
Query: 797 GEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGS 852
G +++ + P P D V ++ S + W P + IT Y +
Sbjct: 10924 GSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ 10983
Query: 853 STELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRD 912
+ L+ S L G QY + A + V + P+D
Sbjct: 10984 WSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKD 11043
Query: 913 LQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE----V 964
L V+V +V+++W P+ S +TGY V+ E G + I T V
Sbjct: 11044 LHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEY------QEEGTQDWIKFKTVTNLECVV 11097
Query: 965 TGLSPGVTYYFKVFA---VSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
TGL G TY F+V A V G + + KL P+ V + V+ T R
Sbjct: 11098 TGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVR 11157
Query: 1022 --AQITGYRL-TVGLTRRGQPRQYNVGPSV------SKYPLRNL--QPASEYTVSLVAIK 1070
A I G + T T G + + +V S ++N + EY +++
Sbjct: 11158 FPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV---- 11213
Query: 1071 GNQESPKATGVFTTLQ--PGSSIPPYNT-EVTETTIVITWTPAPRIGFKLGVRPSQGGEA 1127
N K V T+ PG P N +VT + I+W P P G +
Sbjct: 11214 SNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQP-----------PKDDGGS 11262
Query: 1128 P--------REVTSDSGSIVVSG----------LTPGVEYVYTIQV---LRDGQERDA-P 1165
P ++ D+ +V SG L G EYV+ ++ + G D+ P
Sbjct: 11263 PVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTP 11322
Query: 1166 IVNK-VVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSL 1221
V K +P SPP + + TVSW + ITGY + G+
Sbjct: 11323 TVAKHKFSPPSPPGK-PVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVN 11381
Query: 1222 EEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVP-----PPTDLRFT 1276
+ + + T E+ V + + P SD I P PP + +
Sbjct: 11382 KTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLK 11441
Query: 1277 NIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDN-----AVVLTNLLPG 1331
+ +T + W P S D + ++ Y + A+ + D A + L+ G
Sbjct: 11442 DKSRETADLVWTKPLS-DGGSPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEG 11500
Query: 1332 TEYVVSVSSVYEQHESTPLRGRQKT---GLDSPTGIDFSDITANSFTVHWIAPRATITGY 1388
EY + + E P + + P ++ D+T + I
Sbjct: 11501 NEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVEL-DVTCRDVITVRVGQTIRILA- 11558
Query: 1389 RIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE-------------YVVSIVALNGRE 1435
R++ PE +E +V + L P E Y++S +G
Sbjct: 11559 RVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHA 11618
Query: 1436 ESPLLIGQQSTVSDVP---RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQ 1492
+ ++ V D P ++L+V T + ISW+ P + G + + +
Sbjct: 11619 QGSAIVN----VLDRPGPCQNLKVTNVTKENCTISWENP--------LDNGGSEITNFIV 11666
Query: 1493 EFTVPGSKSTATISG----------LKPGVDYTITVYAVTGRGDSPASSKPISINYRTEI 1542
E+ P K + ++ L +Y V A G P I I
Sbjct: 11667 EYRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPI 11726
Query: 1543 DKPSQ---MQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 1595
D+P + + + D + +KW SP Y V K + +T
Sbjct: 11727 DRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKET 11786
Query: 1596 EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSI------- 1648
++ Y V +N GES V+T + D+ + +
Sbjct: 11787 HYMVDRCVENQIYEFRVQTKNEGGESD-WVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGD 11845
Query: 1649 KIAWESPQGQVSRYRVTYSSPEDGIHELFPAP----DGEEDTAELQGLRP----GSEYTV 1700
I E+ V ++ +D +L +P D D+++ + G +Y V
Sbjct: 11846 TIRLEAGVRGKPFPEVAWTKDKDAT-DLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVV 11904
Query: 1701 SVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKE 1760
+ + + P +LK V+ + W PP G ++ E
Sbjct: 11905 TATNTAGSFVAYATVNVLDKPGPV-RNLKIVDVSSDRCTVCWDPPEDD-GGCEIQNYILE 11962
Query: 1761 KTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV------ 1814
K K + + S++V+ G V E + Y + ++ G T + V
Sbjct: 11963 KC-ETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKY 12021
Query: 1815 ---SPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQ--TPIQRTIKPDV 1865
P VT ++ +T+ W ++ITG+ ++ + P+ ++ P+
Sbjct: 12022 DKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPE- 12080
Query: 1866 RSYTITGLQPGTDYKIYLYTLND------NARSSPVVI-DASTAIDAPSNLRFLATTPNS 1918
R + L P +Y+ + N+ + S PVV D P+N R + TT +S
Sbjct: 12081 RRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHS 12140
Query: 1919 LLVSWQPP----RARITGYIIKYEK--PGSPPREVVPRPRPGV----TEATITGLEPGTE 1968
+ + W P A I GY+++ + P E R E T+T L+ E
Sbjct: 12141 ITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQE 12200
Query: 1969 YTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFV 2023
Y V A NQ +G + EL + + P L PEI D+ ++++K V
Sbjct: 12201 YEFRVCA--QNQ-----VGIGRPAELKEAIK-PKEILEPPEI-DLDASMRKLVIV 12246
Score = 78.6 bits (192), Expect = 7e-14
Identities = 169/767 (22%), Positives = 275/767 (35%), Gaps = 120/767 (15%)
Query: 601 PLQTYPSSSGPVEVFITETPSQPN-------SHPIQWNAPQ---PSHISKYILRWRPKNS 650
P +T P VF+ PS+P + I W P + I+ Y + ++ +
Sbjct: 19696 PSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDD 19755
Query: 651 VGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT 710
WK + YTI GL G Y ++ S+ + G + + +S P +
Sbjct: 19756 TD-WKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASD-------PSDSSDPQIAKE 19807
Query: 711 VTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVS--GFRVEYELSEEGDEP----Q 764
E PL +E+ + V + S + TV G V L + D
Sbjct: 19808 REEE-----PLFDID---SEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA 19859
Query: 765 YLDLPSTATSVNIPDLL--PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV 822
Y+D + TS+ I + KY + + + +L++ T P P + TV V
Sbjct: 19860 YVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGP--PTNITVQDV 19917
Query: 823 DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNI 878
S V+ W P+ AP+ Y I + + + + S +++LQ G Y
Sbjct: 19918 TKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYF 19977
Query: 879 TIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAV 934
+ E P ++ G ++ P L ++ V++ W PE S +
Sbjct: 19978 RVSGENEFGVGIPAETKE---GVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRI 20034
Query: 935 TGYRVDVIPVNLPGEHGQR----LPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-- 988
Y V+ + E GQ+ ++++T V+GL Y+F+VFA + S P
Sbjct: 20035 VHYVVEAL------EKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRE 20088
Query: 989 -LTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
L + P + N TV VR G L V + G+P V S
Sbjct: 20089 LLLPVLIKEQLEPPEIDMKNFPSHTVYVR--------AGSNLKVDIPISGKPLP-KVTLS 20139
Query: 1048 VSKYPLR-NLQPASEYTV---------SLVAIKGNQESPKATGVFTTL---------QPG 1088
PL+ ++ +E T S+ A G E A TT +PG
Sbjct: 20140 RDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPG 20199
Query: 1089 SSI-PPYNTEVTETTIVITWTPAPRIG-------FKLGVRPSQGGEAPREVTSDSGSIVV 1140
P +++TE ++ + W P G L S T + V
Sbjct: 20200 PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKV 20259
Query: 1141 SGLTPGVEYVYTIQV-----LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
LT G EY + I+ + D + V T PP+ + N +TV W
Sbjct: 20260 MKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWV-TNVTRESITVGW 20318
Query: 1196 ERSTT---PDITGYRITTTPTNG---QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249
+ + GY + N Q+ N L V+ T +S GL Y VY
Sbjct: 20319 HEPVSNGGSAVVGYHLEMKDRNSILWQKANKL--VIRTTHFKVT--TISAGLIYEFRVYA 20374
Query: 1250 V------KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP 1290
K S P+ I A PP ++R T+I +++ ++W P
Sbjct: 20375 ENAAGVGKPSHPSEPV--LAIDACEPPRNVRITDISKNSVSLSWQQP 20419
Score = 66.2 bits (160), Expect = 4e-10
Identities = 301/1561 (19%), Positives = 557/1561 (35%), Gaps = 218/1561 (13%)
Query: 628 IQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W+AP S ++ + + + +NS+ K T P Y GL G+ Y+ ++ +
Sbjct: 21403 LTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAE 21462
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
G S+P + T +P P + ++T + + W
Sbjct: 21463 NSAG-------------LSSPSDPSKFTLAVSPVDP--PGTPDYIDVTRETITLKWNPPL 21507
Query: 745 DTVSGFRVEYELSEEGDEPQYLDLPSTATS---VNIPDLLPGRKYIVNVYQ------ISE 795
V Y + + +++ T S + L PG +Y + IS
Sbjct: 21508 RDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISP 21567
Query: 796 DGEQSLILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWS--RPQAPITGYRIV----YS 846
+ S I+ T P P V+ + D I+ R +A + G + +
Sbjct: 21568 PSQSSGIIMTRDENVP-----PIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFK 21622
Query: 847 PSVE-GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES--TPVVIQQETTGTPR 903
VE + + + S +L ++ + + +Y VE S I+ + TP
Sbjct: 21623 DGVEIEKRMNMEITDVLGSTSLF-VRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPG 21681
Query: 904 SDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVNLPGEHGQRLPISRN 959
P ++F +T K+T+ W P + +T Y ++ +
Sbjct: 21682 KVVGP----IRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQ 21737
Query: 960 TFAEVTGLSPGVTYYFKVFAVSH---GR--ESKPLTAQ-QTTKLDAPTNLQFVNETDSTV 1013
++ + L G Y F+V AV+ GR +S P+ AQ Q T DAP + N T +++
Sbjct: 21738 SYTAIK-LINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSI 21796
Query: 1014 LVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN-------LQPASEYTVSL 1066
+ W P + G + + R + + +SK P+ L +EY +
Sbjct: 21797 TLTWARPESD-GGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHV 21855
Query: 1067 VAIKGNQESPKATGVFTTLQ-------PGSSIPPYNTEVTETTIVITWTPA------PRI 1113
+A P A+G+ ++ PG T+ ++TT+ + W+ I
Sbjct: 21856 MAENAAGVGP-ASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEII 21914
Query: 1114 GFKLGVRPSQGGEAPREVTSDS---GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
G+ + + + G+ +V +++ V+ L G EY + + + + D+ V
Sbjct: 21915 GYIIEMCKADLGDW-HKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGT 21973
Query: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT----NGQQGNSLEEVVH 1226
+ + T L+ + + V ++ Y+ TPT SL +H
Sbjct: 21974 IKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIH 22033
Query: 1227 ADQSSCTFD----NLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDT 1282
S T N + +Y ++V K S+ + ++ PP + F ++ +
Sbjct: 22034 TTDSFSTLTVENCNRNDAGKYTLTVENNSGSK-SITFTVKVLDTPGPPGPITFKDVTRGS 22092
Query: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLPGTEYVVSVS 1339
+ W P +D + Y K E +S + + +L G Y VS
Sbjct: 22093 ATLMW-DAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVS 22151
Query: 1340 SVYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR----ATITGYRIR 1391
+V E P + P +D D + +S + W+ P + ITGY +
Sbjct: 22152 AVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLE 22211
Query: 1392 HHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV 1450
+ G H++ + T+ L TEY + A N S S +
Sbjct: 22212 MRQK---GSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKE 22268
Query: 1451 PR-----DLEVV--------AATPTSL---LISWDAPAVTVRYYRITYGETGGNSPVQEF 1494
P+ DL + A +P ++ + AP VT + + ET S
Sbjct: 22269 PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVS----I 22324
Query: 1495 TVPGSKSTATISGLKPGVD--YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQM---- 1548
T ++T T+ G Y +T+ ++ A K S+ I +P +
Sbjct: 22325 TTTKDRTTLTVKDSMRGDSGRYFLTL-------ENTAGVKTFSVTV-VVIGRPGPVTGPI 22376
Query: 1549 QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
+V+ V S + W + +T Y + ++G + + +T++ + L
Sbjct: 22377 EVSSVSAESCVLSWGEPKDGGGTEITNY-IVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 22435
Query: 1605 TVEYVVSVYAQNPSGESQPLVQTAV------TNIDRPKGLAFTDVDVDSIKIAWESPQGQ 1658
+EY V ++N G S+PL + P V +++ I WE P
Sbjct: 22436 YMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHD 22495
Query: 1659 VSRYRVTYSSPEDGIHELFPAPDGE----EDTAELQGLRPGSEYTVSVVALH------DD 1708
+ Y + + + + + E ++ GL G EY AL+
Sbjct: 22496 GGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKAS 22555
Query: 1709 MESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGP 1764
S+P++ + AP + T VT +++S W+ P ++ GY + P + G
Sbjct: 22556 EASRPIMA--QNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGD 22613
Query: 1765 ---MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT-LTSRPAQ--GVVTTLENVSPPR 1818
+K + V+ L YE V A + S+ ++ G VT + +PP+
Sbjct: 22614 GRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPK 22673
Query: 1819 RARVTDATETTITISWRTKTETITGFQVDAVP------ANGQTPIQRTIKPDV-----RS 1867
DA ++ R ++ + V P G + K + R+
Sbjct: 22674 AE--LDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRA 22731
Query: 1868 YTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP---SNLRFLATTPNSLLVSWQ 1924
+ +D Y T+ NA + V +D+P L T ++W
Sbjct: 22732 TAVIKFCDRSDSGKYTLTVK-NASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWS 22790
Query: 1925 PPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKN-- 1978
P+ A IT YI++ + +V P ++ +T L EY V A+
Sbjct: 22791 LPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLS-YVVTRLIKNNEYIFRVRAVNKYG 22849
Query: 1979 ---NQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFV--THPGYDTGNG 2033
+SEP++ R T+P P P I + T ++ + T P D GN
Sbjct: 22850 PGVPVESEPIVARNS-------FTIPSP----PGIPEEVGTGKEHIIIQWTKPESDGGNE 22898
Query: 2034 I 2034
I
Sbjct: 22899 I 22899
Score = 60.8 bits (146), Expect = 1e-08
Identities = 178/828 (21%), Positives = 291/828 (35%), Gaps = 149/828 (17%)
Query: 1263 IIPAVPPPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPS 1319
+I P +L T + + W P + + ++V +K + V + S
Sbjct: 6714 VIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAES 6773
Query: 1320 DNAVVLTNLLPGTEYVVSVSS-----VYEQHES-TPLRGRQKTGLDSPT-GIDFSDITAN 1372
V G EY+ VS+ E E+ P+ R K + P + +D+
Sbjct: 6774 CEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRF 6833
Query: 1373 SFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSI 1428
++ W P A IT Y I + V S T+T++ G EY +
Sbjct: 6834 GVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRV 6893
Query: 1429 VALNGREESPLLIGQQSTVSDV------------PRDLEVVAATPTSLLISWDAP----A 1472
R ++ + +G+ S + P +L T +S+ + W+ P
Sbjct: 6894 -----RAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGG 6948
Query: 1473 VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSK 1532
+ Y I E G ++ ++ + T ++GL+ G Y V A G S S
Sbjct: 6949 SPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEI 7008
Query: 1533 PISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSS--PVTGYRVTTTPKNGPGPTKTKTA 1590
+ +P+ M ++ +D + P + P TGY P PT T
Sbjct: 7009 LGPLTADDAFVEPT-MDLSAFKDGLEVIVPNPITILVPSTGY---------PRPTATWCF 7058
Query: 1591 GPDQTE----MTIEGLQPTVEYVVSVYAQNPSG----ESQPLVQTAVTNID--------R 1634
G E + ++ L E V+S ++ G + + V+T ID
Sbjct: 7059 GDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSA 7118
Query: 1635 PKGLAFTDVDVDSIKIAWESPQ----GQVSRY--------RVTYSSPEDGIHEL-FPAPD 1681
PK L F D+ DS+ + WE P ++ Y R T++ D + +L F PD
Sbjct: 7119 PKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPD 7178
Query: 1682 GEEDTAELQGLRPGSEYTVSVVALHDDMESQPL-------IGTQSTAIPAPTDLKFTQVT 1734
L G EY V A + +P + T +T P ++K+ T
Sbjct: 7179 ----------LVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRT 7228
Query: 1735 PTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKY 1788
S+ W PP ++ GY V P+ G K + + + V+GL Y
Sbjct: 7229 ANSIFLTWDPPKNDGGSRIKGYIVERCPR---GSDKWVACGEPVAETKMEVTGLEEGKWY 7285
Query: 1789 EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT-----------ITISWRTK 1837
V AL S+P++ P + D E +T+ TK
Sbjct: 7286 AYRVKALNRQGASKPSR----------PTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTK 7335
Query: 1838 TE---TITGFQVDAVPANGQTPIQRTIKPDVR----------SYTITGLQPGTDYKIYLY 1884
E T+TG P T +K D R + TI + +
Sbjct: 7336 IELPATVTG---KPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIE 7392
Query: 1885 TLNDNARSSPVV-IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEK 1939
+N R++ VV ++ P+ T S L++W PPR ++IT Y+++
Sbjct: 7393 AVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRA 7452
Query: 1940 PGSPPREVVPRPRPGV--TEATITGLEPGTEYTIYVIALKNNQKSEPL 1985
S EV + V T T L P EY V A EP+
Sbjct: 7453 TDS---EVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPV 7497
Score = 52.8 bits (125), Expect = 4e-06
Identities = 80/336 (23%), Positives = 120/336 (35%), Gaps = 46/336 (13%)
Query: 602 LQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKN-SVGRWKEA 657
++ Y S P + +T+ ++ S + W+AP S I+ Y++ R + W+E
Sbjct: 9120 VEVYDRPSPPRNLAVTDIKAE--SCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEV 9177
Query: 658 TIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
T Y I L P YE ++ ++ +YG + + D V + P
Sbjct: 9178 TNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSD-------KVVIQDPYRLPGPP 9230
Query: 718 FSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA----- 772
P V T S +VSW D Y L + + Y S A
Sbjct: 9231 GKPKVLAR------TKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKV 9284
Query: 773 ----TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPPD-PTVDQV 822
N+P LL G KY +N I E S P PP P V
Sbjct: 9285 GLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDK 9344
Query: 823 DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPE---TANSVTLSDLQPGVQ 875
+SI + W P +PI GY + +N P+ T + +L+ +
Sbjct: 9345 TKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRK 9404
Query: 876 YNITIYAVEENQESTPVVIQQETTG-TPRSDTVPSP 910
Y + AV E ES P +TTG P +D P
Sbjct: 9405 YRFRVKAVNEAGESEP----SDTTGEIPATDIQEEP 9436
Score = 43.9 bits (102), Expect = 0.002
Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 22/204 (10%)
Query: 717 PFSPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTA 772
P P+V + + +S V+SW +D ++ + VE ++EG E Q + +
Sbjct: 24354 PTGPIV-----IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISV 24408
Query: 773 TSVNIPDLLPGRKYIV-----NVYQISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTS 826
T+ I +L Y N + IS+ E S+++ S P AP PT+ V S
Sbjct: 24409 TTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDS 24468
Query: 827 IVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSV-TLSDLQPGVQYNITIY 881
VV W P A I Y + + + E +V ++ +L G++Y +
Sbjct: 24469 CVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVK 24528
Query: 882 AVEENQESTPVVIQQETTGTPRSD 905
ES I + TP+SD
Sbjct: 24529 CENLGGESEWSEISEPI--TPKSD 24550
Score = 41.2 bits (95), Expect = 0.012
Identities = 92/413 (22%), Positives = 157/413 (38%), Gaps = 51/413 (12%)
Query: 1285 VTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSV 1341
++W PP +TN++V K + +S + S + NL Y VS+
Sbjct: 24370 ISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQ 24429
Query: 1342 YEQHESTPLRGRQKTGLDSPTGID-------FSDITANSFTVHWIAPRATITGYRIRHHP 1394
S PL + SP + +T +S V W P A+ G +IR++
Sbjct: 24430 NTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAW-KPPASDGGAKIRNYY 24488
Query: 1395 EHFSGRPREDRVPHSRNSITLT-----NLTPGTEYVVSIVA--LNGREESPLLIGQQSTV 1447
+ + + + I T NL G EY + L G E + +
Sbjct: 24489 LEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPK 24548
Query: 1448 SDVP----------RDLEVVAATPTSLLISWDA-PAVTVRYYRITYGET----GGNSPVQ 1492
SDVP R+L V + +L+ P V++YR G+ G +Q
Sbjct: 24549 SDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYR--QGKEIIADGLKYRIQ 24606
Query: 1493 EFTVPGSKSTATISGLKPGVDYTITVYAV--TGRGDSPASSKPISINYRTEIDKPSQMQ- 1549
EF G I+ + D TVY V T +G S + + + + +I P ++
Sbjct: 24607 EFK--GGYHQLIIASV---TDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEG 24661
Query: 1550 ---VTDVQDNSISVKWLPSSS---PVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
V ++ +S+K +P S PV ++ + G + + + G++
Sbjct: 24662 MGAVHALRGEVVSIK-IPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVE 24720
Query: 1604 PTVEYVVSVYAQNPSGESQPLVQTAVTNI-DRPKGLAFTDVDVDSIKIAWESP 1655
V A+N G Q V+ V ++ D P+G+ +DV DS+ + W P
Sbjct: 24721 RKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEP 24773
Score = 39.3 bits (90), Expect = 0.046
Identities = 46/194 (23%), Positives = 75/194 (38%), Gaps = 22/194 (11%)
Query: 2062 PPTTATPIRH-RPRPYPPNVGQEALSQTTISWAPFQD-----TSEYIISCHPVGTDEEPL 2115
P T TP+ P PP V S ++SW+ +D + Y I TD+
Sbjct: 23947 PVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVR 24006
Query: 2116 QFRVPGTSTSATLTGLTRGATYNIIVEALKD---QQRHKVREEVVTVGNSVNEGLNQPTD 2172
+ T+T T+TGL A Y + A D + E VV + ++P+
Sbjct: 24007 HNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVV-----CKDPFDKPSQ 24061
Query: 2173 DSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEK 2232
+ ++S +V +WE+ G K + LG+ + + S W N K
Sbjct: 24062 PGELEILSISKDSVTLQWEKPECDGGK---EILGYWVEYRQSGDSAWKKSNKERIK---- 24114
Query: 2233 WDRQGENGQMMSCT 2246
D+Q G ++ T
Sbjct: 24115 -DKQFTIGGLLEAT 24127
Score = 37.7 bits (86), Expect = 0.13
Identities = 36/131 (27%), Positives = 53/131 (40%), Gaps = 8/131 (6%)
Query: 894 IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGE 949
I Q+T +D PR ++ +V+ V + WT P S +T Y V+ E
Sbjct: 24737 IDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATT--AE 24794
Query: 950 HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ--TTKLDAPTNLQFVN 1007
R+ +R T V L +Y F+V A + SKP + TK D + +
Sbjct: 24795 RWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDE 24854
Query: 1008 ETDSTVLVRWT 1018
E D T V T
Sbjct: 24855 EVDETREVSMT 24865
Score = 35.0 bits (79), Expect = 0.87
Identities = 38/169 (22%), Positives = 71/169 (42%), Gaps = 17/169 (10%)
Query: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL-PSS---SPVTGYRV 1574
Y V + K + ++ D P ++V+DV +S+++ W P+S S +T Y V
Sbjct: 24727 YVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIV 24786
Query: 1575 TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL--VQTAVTNI 1632
+ A +T T+ L Y V A+N G S+P + +T
Sbjct: 24787 EKCATTAERWLRVGQA--RETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKE 24844
Query: 1633 DRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPD 1681
D+ + + + D +VD + +VS + ++SS ++ + A D
Sbjct: 24845 DKTRAMNY-DEEVDETR--------EVSMTKASHSSTKELYEKYMIAED 24884
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 154 bits (388), Expect = 1e-36
Identities = 299/1365 (21%), Positives = 509/1365 (37%), Gaps = 169/1365 (12%)
Query: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPI-QWNAPQP---SHISKYILRW 645
YG G+ +P+ S + P I E H I QW P+ + IS Y++
Sbjct: 22723 YGPGVPV-ESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDK 22781
Query: 646 RPKNSVGRWKEATIPGHLNSYTIK--GLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTS 703
R K S+ RW + +K L G Y+ ++ ++ G+ E +
Sbjct: 22782 REKKSL-RWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSE--------- 22831
Query: 704 TPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELS-EEGDE 762
SN ++ ++P ++ V + T S ++W V Y L +E D
Sbjct: 22832 ---ASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDT 22888
Query: 763 PQYLDLPSTATSVN----IPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT 818
Q+ + + AT N +PDL G+KY V ++ G S ++ + P
Sbjct: 22889 DQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPD 22948
Query: 819 VDQVDDT--SIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP-----ETANSVTLSDLQ 871
++ DD ++ +R + P + S ++L +T S +L +
Sbjct: 22949 LELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVD 23008
Query: 872 PGVQYNITIYAVE-ENQE----STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
+Y+ Y +E ENQ +T +V +T G P P ++ EV+ VTI
Sbjct: 23009 KVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPG-------PCP-SVKVKEVSRDSVTIT 23060
Query: 927 WTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH 982
W P + V Y V+ + S+ T ++GL G YYF+V +
Sbjct: 23061 WEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSK-TLYRISGLVEGTMYYFRVLPENI 23119
Query: 983 GRESKPLTAQQTTKLD----APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLT 1034
+P + P L+ V+ T STV + W P +++TGY L
Sbjct: 23120 YGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEA--C 23177
Query: 1035 RRGQPRQYNV---GPSVSKYPLRNLQPASEYTVSLVAI--KGNQESPKATGVFTTLQPGS 1089
+ G R V P+V ++ + +L +Y + A KG E P+ T T+Q
Sbjct: 23178 KAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSE-PRETVTAVTVQDLR 23236
Query: 1090 SIPPYNTEV-------------TETTIVITWTPAPRIG-FKLGVRPSQGGEAPREVTSDS 1135
+P + E I I P P F G + + E +
Sbjct: 23237 VLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKV 23296
Query: 1136 GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
+ + T YT+++ I ++ PPT D +T+SW
Sbjct: 23297 AKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISW 23356
Query: 1196 ERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV----- 1247
E ++GY + + + E V +S+ F L+ G EY V
Sbjct: 23357 EPPELDGGAPLSGYVVEQRDAHRPGWLPVSESV--TRSTFKFTRLTEGNEYVFRVAATNR 23414
Query: 1248 YTVKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYS 1303
+ + +S I +P PP L+ ++ D M +TW PP +T ++V
Sbjct: 23415 FGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERK 23474
Query: 1304 PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR-GRQKTGLD--- 1359
V+ + V + + T L G EY V+++ + P R + +D
Sbjct: 23475 EVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIA 23534
Query: 1360 ---SPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNS 1412
P +D T S ++ W P + +TGY I + + P
Sbjct: 23535 PPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIRE 23594
Query: 1413 ITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAAT--PTSLLISWDA 1470
TLT+L G EY ++A N G ++VP ++V P L
Sbjct: 23595 YTLTHLPQGAEYRFRVLACNA--------GGPGEPAEVPGTVKVTEMLEYPDYELDERYQ 23646
Query: 1471 PAVTVRY---YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
+ VR R+T G P+ ++T G + + + + +T V RGDS
Sbjct: 23647 EGIFVRQGGVIRLTIPIKGKPFPICKWTKEG-QDISKRAMIATSETHTELVIKEADRGDS 23705
Query: 1528 ---------PASSKPISINYRTEIDKPSQ----MQVTDVQDNSISVKWLPSS----SPVT 1570
K + I R I P+ ++ D+Q S+ V W P + + +
Sbjct: 23706 GTYDLVLENKCGKKAVYIKVRV-IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADIL 23764
Query: 1571 GYRVTT--TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ-- 1626
GY + PK ++ G T + ++GL+ VEY V A+N G S+PL
Sbjct: 23765 GYILERREVPKAAWYTIDSRVRG---TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEE 23821
Query: 1627 --TAVTNIDRPKGLA----FTDVDVDSIKIAWESPQGQ-VSRYRVTYSSPEDGIHELFPA 1679
T T ++ P+ + DV S+ ++W P+ SR Y ++ + +
Sbjct: 23822 PVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVR 23881
Query: 1680 PDGEEDTAEL---QGLRPGSEYTVSVVALHD------DMESQPLIGTQSTAIPA-PTDLK 1729
+ + T + GL P +EY ++A +D S+P++ P+ P +L+
Sbjct: 23882 HNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELE 23941
Query: 1730 FTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVA 1785
++ S++ QW P ++ GY V + K + GL+ A
Sbjct: 23942 ILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEA 24001
Query: 1786 TKYEVSVYALKDTLTSRP---AQGVVTTL-ENVSPPRRARVTDAT 1826
T+YE V+A +T SRP A + T L +P R + D T
Sbjct: 24002 TEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVT 24046
Score = 148 bits (373), Expect = 7e-35
Identities = 289/1429 (20%), Positives = 524/1429 (36%), Gaps = 170/1429 (11%)
Query: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
D+T T+ ++ + + P S + ++ + ++SW + Y
Sbjct: 12868 DYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 12927
Query: 756 LSE-EGDEPQYLDLPSTA--TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQ 807
+ + E P + + +T TS ++ L+ G +Y N Y + + ++ +
Sbjct: 12928 VDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNP 12987
Query: 808 TTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNL-PETA 862
P P + + + V W P +PITGY + + + T++N P
Sbjct: 12988 YDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIE 13047
Query: 863 NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK 922
++ + LQ G +Y + A+ + P + P + + T
Sbjct: 13048 RTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSS 13107
Query: 923 VTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKV 977
V++ W P S + GY V+V + LP + + T EVTGL Y F+V
Sbjct: 13108 VSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRV 13167
Query: 978 FAVSHGRESKP-----------LTAQQTTKLDAPTNLQFVNETDST----VLVRWTPPRA 1022
+AV+ S P + +LDA + T V V+ PP
Sbjct: 13168 YAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPP-P 13226
Query: 1023 QITGYRLTVGLTRR-GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
+IT + V L R G + + + N A +Y ++L G +E V
Sbjct: 13227 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13286
Query: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDS 1135
T PG + E+++ + +TW P +P I + + R ++ T S
Sbjct: 13287 LDT--PGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECS 13344
Query: 1136 G-SIVVSGLTPGVEYVYTIQVLRD------GQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
S V+ L G Y + + + G+ RDA V TP P +L + + +
Sbjct: 13345 KTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDA--VKASQTP-GPVVDLKVRSVSKS 13401
Query: 1189 GVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
++ W++ + I GY + + N + V+ + + +L+ G EY
Sbjct: 13402 SC-SIGWKKPHSDGGSRIIGYVVDFLT----EENKWQRVMKSLSLQYSAKDLTEGKEYTF 13456
Query: 1246 SVYTVKDDKESVPISDTIIP---AVPPPTDLRFTNIGPDT-------------MRVTWAP 1289
V ++ E P T++ V P DL+ PD + + P
Sbjct: 13457 RVSAENENGEGTPSEITVVARDDVVAPDLDLKGL---PDLCYLAKENSNFRLKIPIKGKP 13513
Query: 1290 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL-------PGTEYVVSVSSVY 1342
PS+ S K E+ +A + +++ V T L+ +Y +++ +V
Sbjct: 13514 APSV---------SWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVA 13564
Query: 1343 EQHEST-PLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEH 1396
E T ++ K G+ PTG I F ++TA + T+ W P+ + IT Y I +
Sbjct: 13565 GTKEGTISIKVVGKPGI--PTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNY-ILEKRDS 13621
Query: 1397 FSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------GREESPLLIGQQSTVSDV 1450
+ + + + +T L G EY + A N G + P++ V D
Sbjct: 13622 VNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDA 13681
Query: 1451 PRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATIS 1506
P +V S+ ++W P T + Y + + E + P ++
Sbjct: 13682 PPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVT 13741
Query: 1507 GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP-- 1564
GL G++Y V A+ G S + ID P + +V ++ NS+++ W
Sbjct: 13742 GLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPK 13801
Query: 1565 --SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1622
+TGY V K + T+ L +Y + A+N +G
Sbjct: 13802 YDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAIS 13861
Query: 1623 PLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQV----------------SRYRVTY 1666
++ T I + + A T V +IK G S +
Sbjct: 13862 APSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGK 13921
Query: 1667 SSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT 1726
I ++ P T + + EYT++ + P P
Sbjct: 13922 DIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGP-PG 13980
Query: 1727 DLKFTQVTPTSLSAQWTPPNVQLTGYRVR--VTPKEKTGPMKEINLAPDSSSV--VVSGL 1782
++ + V+ + WTPP ++ G ++ + K +T + ++ D S V + L
Sbjct: 13981 PVEISNVSAEKATLTWTPP-LEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKL 14039
Query: 1783 MVATKYEVSVYALKDTLTSRPAQG----VVTTLENVSPPRRARVTDATETTITISWRTKT 1838
+ +Y V A+ P Q +V PP + V++ T+ T T+SW+
Sbjct: 14040 IQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPV 14099
Query: 1839 E----TITGFQVDAVPANGQTPIQRTIKPDVRSY--TITGLQPGTDYKIYLYTLN----- 1887
+ ITG+ V+ + R IK V +TGLQ G+ Y+ + N
Sbjct: 14100 DDGGSEITGYHVERREKKSLRWV-RAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 14158
Query: 1888 --DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPG 1941
A S ++ DA+ PSN TT S ++W P ITGY+++++K G
Sbjct: 14159 PPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVG 14218
Query: 1942 SPPREVVPRPRPG----VTEATITGLEPGTEYTIYVIALKNNQKSEPLI 1986
E + G +T+ + L+ +Y + A+ + EP +
Sbjct: 14219 D---EAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAV 14264
Score = 145 bits (367), Expect = 4e-34
Identities = 292/1351 (21%), Positives = 505/1351 (37%), Gaps = 184/1351 (13%)
Query: 780 LLPGRKYIVNVYQISEDG-----EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP 834
L+ +YI V +++ G E I++ + T P P P I+++W++P
Sbjct: 22707 LIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKP 22766
Query: 835 QAP----ITGYRIVYSPSVEGSSTELNLPETANSVTL--SDLQPGVQYNITIYAVEENQE 888
++ I+ Y + T +N L + L G Y + AV
Sbjct: 22767 ESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGN 22826
Query: 889 STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
S P + S T P + V+ T +++ WT P + + GY +++
Sbjct: 22827 SEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEK 22886
Query: 945 NLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA----QQTTKLDA 999
+ + + RNT V L G Y F+V AV+ S+ + + +++
Sbjct: 22887 DTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEI 22946
Query: 1000 PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP-----------RQYNVGPSV 1048
P +L+ ++ TV +R RL V ++ R P + +
Sbjct: 22947 P-DLELADDLKKTVTIRAG------ASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTT 22999
Query: 1049 SKYPLR-----NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI 1103
Y L N A +YT+ G + + V+ T P S+ EV+ ++
Sbjct: 23000 ESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKV--KEVSRDSV 23057
Query: 1104 VITWT------PAPRIGFKLGVRPSQGGEAPREVTSDSGSIV-VSGLTPGVEYVYTIQ-- 1154
ITW AP + + R + T S ++ +SGL G Y + +
Sbjct: 23058 TITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPE 23117
Query: 1155 ----VLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYR 1207
+ + DA +V++V PL P ++ T +T++WE+ +TGY
Sbjct: 23118 NIYGIGEPCETSDAVLVSEV--PLVPAKLEVVDVTKST--VTLAWEKPLYDGGSRLTGYV 23173
Query: 1208 ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY-----------------NVSVYTV 1250
+ ++ + + T +L+ G +Y V+ TV
Sbjct: 23174 LEACKAGTERWMKVV-TLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTV 23232
Query: 1251 KD-------DKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYS 1303
+D D ++P +PA P +L + + PPP+ F
Sbjct: 23233 QDLRVLPTIDLSTMPQKTIHVPA-GRPVEL--------VIPIAGRPPPAASW--FFAGSK 23281
Query: 1304 PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHESTPLRGRQKTGLDSPT 1362
++E E + + T + EY + + +V E+ + K G PT
Sbjct: 23282 LRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPG--PPT 23339
Query: 1363 G-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSG-RPREDRVPHSRNSITLT 1416
G I +I A S T+ W P A ++GY + H G P + V +R++ T
Sbjct: 23340 GPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESV--TRSTFKFT 23397
Query: 1417 NLTPGTEYVVSIVALN----GREESPLLIGQQSTVS--DVPRDLEVVAATPTSLLISWDA 1470
LT G EYV + A N G +I +S++ P L++ + + ++W
Sbjct: 23398 RLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYP 23457
Query: 1471 P----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD 1526
P V Y + E + V+ VP + + +GL G++Y V A+ RG
Sbjct: 23458 PEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGS 23517
Query: 1527 SPAS--SKPI-SINYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPK 1579
S SKPI +++ KP +VTD S+S+ W S VTGY +
Sbjct: 23518 GKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKV 23577
Query: 1580 NGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLA 1639
+ TK T E T+ L EY V A N G +P + L
Sbjct: 23578 DQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEM--LE 23635
Query: 1640 FTDVDVDS-IKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEY 1698
+ D ++D + QG V R + I + +G+ D ++ + +
Sbjct: 23636 YPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKW--TKEGQ-DISKRAMIATSETH 23692
Query: 1699 TVSVVALHDDMES------------QPLIGTQSTAIPAPTD----LKFTQVTPTSLSAQW 1742
T V+ D +S + + + I +P L++ + S+ W
Sbjct: 23693 TELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSW 23752
Query: 1743 TPP----NVQLTGYRV--RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1796
PP + GY + R PK I+ +S+VV GL +Y V A
Sbjct: 23753 RPPADDGGADILGYILERREVPK---AAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAEN 23809
Query: 1797 DTLTSRP--AQGVVTTLENVSPPRRA----RVTDATETTITISW-RTKTE---TITGFQV 1846
S+P ++ VT ++PP V D T++++++SW R K + +TG+ +
Sbjct: 23810 QFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYI 23869
Query: 1847 DAVPANGQTPIQRTIKPDVRS--YTITGLQPGTDYKIYLYTLND------NARSSPVVI- 1897
+ + ++ K + + YT+TGL P +Y+ + ND + S PVV
Sbjct: 23870 ERKETSTDKWVRHN-KTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCK 23928
Query: 1898 DASTAIDAPSNLRFLATTPNSLLVSWQPPRA----RITGYIIKYEKPGSPPREVVPRPRP 1953
D P L L+ + +S+ + W+ P I GY ++Y + G + + R
Sbjct: 23929 DPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERI 23988
Query: 1954 GVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
+ TI GL TEY V A S P
Sbjct: 23989 KDKQFTIGGLLEATEYEFRVFAENETGLSRP 24019
Score = 135 bits (339), Expect = 6e-31
Identities = 320/1486 (21%), Positives = 522/1486 (35%), Gaps = 215/1486 (14%)
Query: 771 TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVR 830
T S++ D KYI+ + S G +S ++ P P + V +V S +
Sbjct: 17581 TQLSIDNCDRNDAGKYILKLENSS--GSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLV 17638
Query: 831 WSRP----QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN 886
W P A + Y I S + ++ + S + +L G Y + A E
Sbjct: 17639 WEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEF 17698
Query: 887 QESTPVVIQQETTGTPRSDTVPSPRD-LQFVEVTDVKVTIMWTPPE----SAVTGYRVDV 941
PV ET ++ PSP + +V+ ++MW PE S V GY V++
Sbjct: 17699 GVGVPV----ETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEM 17754
Query: 942 IPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-----------LT 990
P E + S+ A VTGLS G Y F+V A + +S P LT
Sbjct: 17755 QPKGT--EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLT 17812
Query: 991 AQQTTKLDAPT-NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP----RQYNVG 1045
Q + KL T ++Q + + V P R + + G+P + NV
Sbjct: 17813 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRP--------RPNISWVKDGEPLKQTTRVNVE 17864
Query: 1046 PSVSKYPLR----NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN-TEVTE 1100
+ + L N +YTV+ G + + V +PG + P EV+
Sbjct: 17865 ETATSTVLHIKEGNKDDFGKYTVTATNSAGT--ATENLSVIVLEKPGPPVGPVRFDEVSA 17922
Query: 1101 TTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYV 1150
+VI+W P G G + S R+ T+ + +V ++ L G EY
Sbjct: 17923 DFVVISWEPPAYTG---GCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQ 17979
Query: 1151 YTIQVLRDGQERDAPIVNKVVTPLSP-----PTNLHLEANPDTGVLTVSWERSTTPD--- 1202
+ I + + AP+ +K V P P + + V W
Sbjct: 17980 FRI-FAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTK 18038
Query: 1203 ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN--VSVYTVKDDKESVPIS 1260
I GY + N L + D T L GLEY VS + + +S
Sbjct: 18039 IIGYHLEQKEKNSILWVKLNKTPIQDTKFKT-TGLDEGLEYEFKVSAENIVGIGKPSKVS 18097
Query: 1261 DTIIPAVP--PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELS 1315
+ + P PP I + + + W P +T ++V K+ D +
Sbjct: 18098 ECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEK---KDLPDGRWMK 18154
Query: 1316 ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFT 1375
S TN+L TE+ VS V +Q + R G S ITA
Sbjct: 18155 AS-------FTNVLE-TEFTVS-GLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARD-- 18203
Query: 1376 VHWIAPRATITG-YR---IRHHPEHF------SGRPREDRV--------------PHSRN 1411
AP A++ Y+ + H E F G+P D V ++
Sbjct: 18204 -EIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKS 18262
Query: 1412 SITLTNL-------TPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSL 1464
+I T L T G +Y++ + + G + P+ + L+V T
Sbjct: 18263 TIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKC 18322
Query: 1465 LISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
++W+ P + +Y I ET S Q T + + ++ L PG +Y V A
Sbjct: 18323 YLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYK-VTKLLPGNEYIFRVMA 18381
Query: 1521 VTGRG-DSPASSKPISI-NYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRV 1574
V G P S P++ N PS +V+ + +S+ V W + + GY +
Sbjct: 18382 VNKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYIL 18441
Query: 1575 TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT------- 1627
K G TK + + GL Y V A+N +G +P +
Sbjct: 18442 EKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACD 18501
Query: 1628 AVTNIDRPKGLAFTDVDVDSIKIAWESP----QGQVSRYRVTYSSPEDGIHELFPAPDGE 1683
A+ P TD S+ +AW P V Y V P G
Sbjct: 18502 ALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGL 18561
Query: 1684 EDTA-ELQGLRPGSEYTVSVVALHDDMESQPL-----IGTQSTAIPAPTDLKFTQVTPTS 1737
+ + L+ +EY + A++ + +P + Q P +L
Sbjct: 18562 QGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVV 18621
Query: 1738 LSAQWTPPNVQLTGYRVRVTPKEKTGPM----KEINLAPDSSSVVVSGLMV------ATK 1787
L A T R+ VT K + P K + D + + V+ T+
Sbjct: 18622 LRASAT--------LRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTR 18673
Query: 1788 YEVSVY--ALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETI 1841
++ Y L++ S+ A V L++ S P + + + ++T+SW I
Sbjct: 18674 FDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKI 18733
Query: 1842 TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1901
T + V+ + T ++ I LQ G Y + N+ P
Sbjct: 18734 TNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPV 18793
Query: 1902 AIDAP----SNLRFLATTPNSLLVSWQPPRA----RITGYIIKYEKPGSPPREVVPRPRP 1953
+ P + + T N+ + W+ P + +ITGY+++ + GS + +
Sbjct: 18794 KVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVK- 18852
Query: 1954 GVTEATITGLEPGTEYTIYVIALKNNQKSE------PLIGRKKTDELPQLVTLPHP--NL 2005
EATI+GL G EY V A+ +S+ P+I R E+ V LP N+
Sbjct: 18853 -TLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIAR--DIEIKPSVELPFHTFNV 18909
Query: 2006 HGPEIL--DVP---------------STVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQ 2048
E L DVP T+++T V T + + S + VG
Sbjct: 18910 KAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEAS--KEDVGT 18967
Query: 2049 QMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAP 2094
+ + T P T + P P + + + TISW P
Sbjct: 18968 YELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNP 19013
Score = 133 bits (334), Expect = 2e-30
Identities = 288/1457 (19%), Positives = 519/1457 (35%), Gaps = 224/1457 (15%)
Query: 728 VTEITASSFVVSWVSASDTVSGFRVEY--ELSEEGDEP-QYLDLPSTATSVNIPDLLPGR 784
V+ ++A S V+SW D Y E E G Q ++ T + + L
Sbjct: 22253 VSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYM 22312
Query: 785 KYIVNV-----YQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPIT 839
+Y V + +S+ E + I++ P AP P V V ++ +RW P
Sbjct: 22313 EYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGG 22372
Query: 840 GYRIVYSPSVEGSST-----ELNLPETANSVTLSDLQPGVQYNITIYAV------EENQE 888
I Y + +T E +P + ++ L G++Y YA+ + ++
Sbjct: 22373 SKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEA 22432
Query: 889 STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
S P++ Q + V +P + +VT V+++W+ P S V GY ++ PV
Sbjct: 22433 SRPIMAQ---------NPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPV 22483
Query: 945 NLPGEHGQRLP----ISRNTFAEVTGLSPGVTYYFKVFA------VSHGRESK-PLT--- 990
+ G+ G+ L I + F VT LS G TY F+V A +S G ES P+T
Sbjct: 22484 SEVGD-GRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRD 22542
Query: 991 --AQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR-------- 1040
A +LDA + V + LV A + G + +G
Sbjct: 22543 EYAPPKAELDARLHGDLVTIRAGSDLVL----DAAVGGKPEPKIIWTKGDKELDLCEKVS 22598
Query: 1041 -QYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTL--QPGSSIPPYNTE 1097
QY + + + + +YT+++ N KA V + PG +
Sbjct: 22599 LQYTGKRATAVIKFCDRSDSGKYTLTVK----NASGTKAVSVMVKVLDSPGPCGKLTVSR 22654
Query: 1098 VTETTIVITWTPAPRIGFKLGVRPSQGGEAP-------REVTSDSGSIVVSGLTPGVEYV 1150
VT+ + W+ P + G A R TS ++V G P + YV
Sbjct: 22655 VTQEKCTLAWS-----------LPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYV 22703
Query: 1151 YTIQVLRDGQE----------------RDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVS 1194
T +++++ + PIV + + P + E + +
Sbjct: 22704 VT-RLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQ 22762
Query: 1195 WERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK 1251
W + + +I+ Y + + + + + +L G +Y V V
Sbjct: 22763 WTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVN 22822
Query: 1252 DDKESVP--ISDTIIPAVP-----PPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSP 1304
S P S+ I P PP+ R + ++ + W P D +V Y
Sbjct: 22823 AAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKP-MYDGGTDIVGYVL 22881
Query: 1305 VKNEEDVAE-----LSISPSDNAVVLTNLLPGTEYVVSVSSV----YEQHESTPLRGRQK 1355
E+D + + + + + +L G +Y V++V ++ +
Sbjct: 22882 EMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPV 22941
Query: 1356 TGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP-------- 1407
++ P ++ +D + T+ A + R P + D
Sbjct: 22942 ERIEIPD-LELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTE 23000
Query: 1408 -HSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLI 1466
+S + N +Y + +G++ + +L+ T P ++V + S+ I
Sbjct: 23001 SYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCP-SVKVKEVSRDSVTI 23059
Query: 1467 SWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA-- 1520
+W+ P + V Y + E + + T SK+ ISGL G Y V
Sbjct: 23060 TWEIPTIDGGAPVNNYIVEKREAAMRA-FKTVTTKCSKTLYRISGLVEGTMYYFRVLPEN 23118
Query: 1521 VTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTT 1576
+ G G+ +S + ++ + P++++V DV +++++ W S +TGY +
Sbjct: 23119 IYGIGEPCETSDAVLVSEVPLV--PAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEA 23176
Query: 1577 TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPK 1636
K T P E T+ L +Y+ + AQN G S+P + +
Sbjct: 23177 CKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLR 23236
Query: 1637 GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDG--EEDTAELQGLRP 1694
L D+ K P G+ + + F A E + ++
Sbjct: 23237 VLPTIDLSTMPQKTI-HVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTK 23295
Query: 1695 GSEYTVSVVALHDD----MESQPLIGTQSTAI---------PAPTDLKFTQVTPTSLSAQ 1741
++ T+ + D +E + + GT S I P +K ++ TS++
Sbjct: 23296 VAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITIS 23355
Query: 1742 WTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1797
W PP + L+GY V + G + P S SV S E + Y +
Sbjct: 23356 WEPPELDGGAPLSGYVVEQRDAHRPGWL------PVSESVTRSTFKFTRLTEGNEYVFRV 23409
Query: 1798 TLTSRPAQGVVTTLENVS---------PPRRARVTDATETTITISWRTKTET----ITGF 1844
T+R G E + PP ++ D + +T++W + +TG+
Sbjct: 23410 AATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGY 23469
Query: 1845 QVDAVPANGQTPIQRTIKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSP-------VV 1896
V+ ++ P + Y TGL G +Y+ + +N P V
Sbjct: 23470 IVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVA 23529
Query: 1897 IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPR 1952
+D P N R TT S+ ++W P +++TGY+I+ +K
Sbjct: 23530 MDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTP 23589
Query: 1953 PGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILD 2012
+ E T+T L G EY V+A EP +
Sbjct: 23590 TKIREYTLTHLPQGAEYRFRVLACNAGGPGEP--------------------------AE 23623
Query: 2013 VPSTVQKTPFVTHPGYD 2029
VP TV+ T + +P Y+
Sbjct: 23624 VPGTVKVTEMLEYPDYE 23640
Score = 132 bits (332), Expect = 4e-30
Identities = 282/1282 (21%), Positives = 484/1282 (37%), Gaps = 198/1282 (15%)
Query: 611 PVEVFITETPSQPNSHPIQWNAP---QPSHISKYILRWRPKNSVGRWKEATIPGHLNSYT 667
PV V + E +S + W P S I Y+++ R W T S+
Sbjct: 13293 PVNVTVKEISK--DSAYVTWEPPIIDGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFR 13349
Query: 668 IKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSES 727
+ L+ G Y ++ + +YG + T + V TP P+V
Sbjct: 13350 VANLEEGKSYFFRVFAENEYGIGDPGE------------TRDAVKASQTP-GPVVDLK-- 13394
Query: 728 VTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
V ++ SS + W + G+ V++ L+EE + + S + + DL G
Sbjct: 13395 VRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMK--SLSLQYSAKDLTEG 13451
Query: 784 RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITG 840
++Y V +E+GE + T PD + + D + + + R + PI G
Sbjct: 13452 KEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKG 13511
Query: 841 YRIVYSPSVE--------GSSTELNLPETANSVTLS--DLQPGV--QYNITIYAVEENQE 888
+PSV + T +++ +A + TL D Q +Y IT+ V +E
Sbjct: 13512 KP---APSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13568
Query: 889 STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
T I + G P T P ++F EVT +T+ W PP+ S +T Y ++
Sbjct: 13569 GT---ISIKVVGKPGIPTGP----IKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDS 13621
Query: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKL-D 998
+ + TF VT L G+ Y F+V + V G +S+P+ A+ + D
Sbjct: 13622 VNNKWVTCASAVQKTTF-RVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPD 13680
Query: 999 APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP-SVSKYPL 1053
AP V+ +V + WT P+ + ITGY L ++ N P + + +
Sbjct: 13681 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV 13740
Query: 1054 RNLQPASEYTVSLVAIK----GNQESPKATGVFTTLQPGSSIPPYNTEV---TETTIVIT 1106
L EY ++AI G P V L P PP EV T ++ +
Sbjct: 13741 TGLTEGLEYEFRVMAINLAGVGKPSLPSEPVV--ALDPID--PPGKPEVINITRNSVTLI 13796
Query: 1107 WT-PAPRIGFKLGVR-------PSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD 1158
WT P G KL PS+ V + V+ L G +Y + I+
Sbjct: 13797 WTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNT 13856
Query: 1159 GQERDAPIVN----------KVVTPLSPPT---NLHLEANPDTGVLTV-----------S 1194
AP + + T + PT L ++A DT VL S
Sbjct: 13857 AGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAG-DTIVLNAISILGKPLPKSS 13915
Query: 1195 WERS----TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
W ++ DIT +IT+TPT+ +++ D T +P + V V
Sbjct: 13916 WSKAGKDIRPSDIT--QITSTPTSSML--TIKYATRKDAGEYTITATNP---FGTKVEHV 13968
Query: 1251 KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEED 1310
K T++ PP + +N+ + +TW PP D + + Y K E
Sbjct: 13969 KV---------TVLDVPGPPGPVEISNVSAEKATLTWTPPLE-DGGSPIKSYILEKRETS 14018
Query: 1311 VAELSISPSDNAV---VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD------SP 1361
++ D V T L+ G EY+ VS+V + P++ +D P
Sbjct: 14019 RLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPP 14078
Query: 1362 TGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
+ S++T N+ TV W P + ITGY + + R + P S +T
Sbjct: 14079 EKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTG 14138
Query: 1418 LTPGTEYVVSIVALNGREESP-------LLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
L G+ Y + A N P +L+ + P + V T S ++W
Sbjct: 14139 LQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGK 14198
Query: 1471 P----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKPGVDYTITVYAVTGRG 1525
P + + Y + + + G + +++ T + T + L+ Y + A+ G
Sbjct: 14199 PHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAG 14258
Query: 1526 -DSPASSKPISINYR---TEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNG 1581
PA + I R + + ++++ T V +S++ VT T N
Sbjct: 14259 VGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNI 14318
Query: 1582 PGPTKTKTAGPDQTEMTIE---GLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRP-KG 1637
+ + + I T ++V+++ +NP+G+ V V + P
Sbjct: 14319 NLKNRANIENTESFTLLIIPECNRYDTGKFVMTI--ENPAGKKSGFVNVRVLDTPGPVLN 14376
Query: 1638 LAFTDVDVDSIKIAWESP----QGQVSRY--------RVTYSSPEDGIHELFPAPDGEED 1685
L TD+ DS+ + W+ P +++ Y R +YS+ H+
Sbjct: 14377 LRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKC--------- 14427
Query: 1686 TAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ---STAIPAPTD-LKFTQVTPTSLSAQ 1741
T ++ GL G EY V+A ++ +P T+ ++ P+P D L +T +++S
Sbjct: 14428 TYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLA 14487
Query: 1742 WTPP----NVQLTGYRVRVTPK 1759
W P ++TGY + K
Sbjct: 14488 WPKPKHDGGSKITGYVIEAQRK 14509
Score = 129 bits (324), Expect = 3e-29
Identities = 296/1415 (20%), Positives = 523/1415 (36%), Gaps = 202/1415 (14%)
Query: 728 VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT----SVNIPDLLPG 783
+ ++++ V W D G ++ + E+ + + + +AT + L+ G
Sbjct: 11808 IVDVSSDRCTVCWDPPEDD-GGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEG 11866
Query: 784 RKYIVNVYQISEDG-----EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ--- 835
+YI V ++ G E +++ ++ P P P V +V + V W+ P+
Sbjct: 11867 NEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDG 11926
Query: 836 -APITGYRIVYSPSVEGSSTELN---LPETANSVTLSDLQPGVQYNITIYAVEENQESTP 891
ITGY + +N +PE V +L P +Y + A E P
Sbjct: 11927 GKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKV--QNLLPDHEYQFRVKAENEIGIGEP 11984
Query: 892 VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNL- 946
+ + + P + + V+ T +T+ W P + + GY V++ P
Sbjct: 11985 SLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIAD 12044
Query: 947 --PGEHGQRL----PISRNTFAEVTGLSPGVTYYFKVFA---VSHGRESKPLTAQQTTKL 997
P E +R + R F VT L Y F+V A V GR ++ A + ++
Sbjct: 12045 ASPDEGWKRCNAAAQLVRKEFT-VTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEI 12103
Query: 998 DAPTNLQFVNETDSTVLVRWT-----------PPRAQITGYRLTV-GLTRRGQPRQYNVG 1045
P + V+VR P ++T ++ + + R+GQ +
Sbjct: 12104 LEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDT- 12162
Query: 1046 PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105
+ P + +Y+++LV G + V T P S + ++VT+T+ +
Sbjct: 12163 MAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKV--SDVTKTSCHV 12220
Query: 1106 TWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQV 1155
+W P G G + + RE + S V V+ L PG EY + +
Sbjct: 12221 SWAPPENDG---GSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTA 12277
Query: 1156 LRD---GQERDAPIVNKVVTPLS---PPTNLHLEANPDTGVLTVSWE---RSTTPDITGY 1206
+ + G D P PLS PP L + T++W R I GY
Sbjct: 12278 VNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSA-TLAWLPPLRDGGAKIDGY 12336
Query: 1207 RITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKESVPISD 1261
IT+ Q + E S L G +Y V V +E+ + +
Sbjct: 12337 -ITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYE 12395
Query: 1262 TIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK---NEEDV---AELS 1315
+PP + P+ + + I+ + + K E++V + L+
Sbjct: 12396 AKEQLLPPKI------LMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLA 12449
Query: 1316 ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP----TGIDFSDITA 1371
+ +D++ +L + S E T + + +D+P D SDI A
Sbjct: 12450 VHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDA 12509
Query: 1372 NSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH----SRNSITLTNLTPGTEYVVS 1427
++ ++ W P G I ++ R D V ++ S + L PG EY+
Sbjct: 12510 DACSLSWHIPLED-GGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFR 12568
Query: 1428 IVALN--GREE---SPLLIGQ-QSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRIT 1481
+ A N G E SP ++ Q V P++ V + ++WD P
Sbjct: 12569 VRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRP---------- 12618
Query: 1482 YGETGGNSPVQEFTVPGSKSTATI----------------SGLKPGVDYTITVYAVTGRG 1525
++ G SP+ + + + + + +GL G++Y+ +YA+ G
Sbjct: 12619 --DSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAG 12676
Query: 1526 DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPKNG 1581
SP S + R +D P + +V DV +++S+ W S + GY V G
Sbjct: 12677 SSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPG 12736
Query: 1582 PGPTKTKTAGPD--QTEMTIEGLQPTVEYVVSVYAQN------PSGESQP---LVQTAVT 1630
+ TA Q E T GL+ +Y A+ PS S P L +
Sbjct: 12737 DKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPP 12796
Query: 1631 NIDRPKGL-------AFTDVDVDSIKIAWESPQGQVS-RYRVTYSSPEDGIHELFPAPDG 1682
ID + A T+V +D+ + P VS + T P +GI A
Sbjct: 12797 RIDLSVAMKSLLTVKAGTNVCLDA--TVFGKPMPTVSWKKDGTLLKPAEGIK---MAMQR 12851
Query: 1683 EEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQ 1741
T EL + ++ A + I + P P +K ++
Sbjct: 12852 NLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLS 12911
Query: 1742 WTPP----NVQLTGYRVRVTPKEKTGP-MKEINLAPDSSSVVVSGLMVATKYEVSV---- 1792
W PP ++T Y V +E + P +++ +S V L+ +Y+ +
Sbjct: 12912 WEPPLEDGGSEITNY--IVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAEN 12969
Query: 1793 -YALKDTLTSRPAQGVVTTLENVSPPRRAR---VTDATETTITISWRTKTE----TITGF 1844
Y + D + + PA PP R +++ T+ +T+SW+ + ITG+
Sbjct: 12970 KYGVGDPVFTEPA----IAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGY 13025
Query: 1845 QVDAVPANGQTPIQRTIKPDV-RSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI 1903
++ + KP + R+ TGLQ GT+Y+ + +N P DAS A
Sbjct: 13026 LLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKP--SDASKAA 13083
Query: 1904 DA---------PSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPR 1950
A P+ + TT +S+ +SW P + I GY+++ ++ S
Sbjct: 13084 YARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNL 13143
Query: 1951 PRP-GVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
P+ T +TGL T+Y V A+ S+P
Sbjct: 13144 PQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDP 13178
Score = 123 bits (309), Expect = 2e-27
Identities = 282/1358 (20%), Positives = 482/1358 (35%), Gaps = 200/1358 (14%)
Query: 780 LLPGRKYIVNVYQISEDGE----QSLILSTSQTTAPDAPPD-PTVDQVDDTSIVVRWSRP 834
L+ G +YI V ++ G+ QS + P PP+ P V V + V W RP
Sbjct: 14039 LIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRP 14098
Query: 835 Q----APITGYRIVYSPSVEGSSTE-LNLPETANSVTLSDLQPGVQYNITIYA-----VE 884
+ ITGY + + P + ++ LQ G Y + A +
Sbjct: 14099 VDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 14158
Query: 885 ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVD 940
E++ V+ ++ P + P D T ++ W P +TGY V+
Sbjct: 14159 PPSEASDSVLMKDAAYPPGPPSNPHVTD-----TTKKSASLAWGKPHYDGGLEITGYVVE 14213
Query: 941 VIPVN----LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ--QT 994
V + G L I++ V L Y F++ A++ +P +
Sbjct: 14214 HQKVGDEAWIKDTTGTALRITQFV---VPDLQTKEKYNFRISAINDAGVGEPAVIPDVEI 14270
Query: 995 TKLDAPTNLQFVNETDSTVLVR-------WTP----PRAQITGYRLTVGLTRRGQPRQYN 1043
+ + + + E T++VR + P P ++T + + L R
Sbjct: 14271 VEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTE 14330
Query: 1044 VGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI 1103
++ P N ++ +++ G + V T P ++ P T++T+ ++
Sbjct: 14331 -SFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRP--TDITKDSV 14387
Query: 1104 VITWT-PAPRIGFKLGVRPSQGGEAPREVTSDSGS------IVVSGLTPGVEYVYTIQVL 1156
+ W P G ++ + EA R+ S + + V+GL+ G EY + +
Sbjct: 14388 TLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAE 14447
Query: 1157 RD---GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITT 1210
+ G+ + K SPP +L++ + ++++W + ITGY I
Sbjct: 14448 NEYGIGEPTETTEPVKASEAPSPPDSLNI-MDITKSTVSLAWPKPKHDGGSKITGYVIEA 14506
Query: 1211 TPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTII----PA 1266
Q + V + C NL+ G EY V V S P +
Sbjct: 14507 QRKGSDQWTHITTVKGLE---CVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQT 14563
Query: 1267 VPPPTDLR-------FTNIGPDT---MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316
+ P DLR G + + V P P++ K + + + +
Sbjct: 14564 MLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTW----------KKGDQILKQTQ 14613
Query: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL-------------DSPTG 1363
+ + +L E V S S Y PL R G PTG
Sbjct: 14614 RVNFETTATSTILNINECVRSDSGPY------PLTARNIVGEVGDVITIQVHDIPGPPTG 14667
Query: 1364 -IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNL 1418
I F +++++ T W P I+ Y + S E R + T L
Sbjct: 14668 PIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTD-STTWVELATTVIRTTYKATRL 14726
Query: 1419 TPGTEYVVSIVALN------GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP- 1471
T G EY + A N G + ++ V P +V A T S+ ISW P
Sbjct: 14727 TTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPL 14786
Query: 1472 ---AVTVRYYRITYGETGGN--SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD 1526
+ Y + E G V + VPG+ + SGL G+ Y V A G
Sbjct: 14787 SDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKS--SGLTDGIAYEFRVIAENMAGK 14844
Query: 1527 SPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGP 1582
S S + ID P + ++ +++++KW +T Y V
Sbjct: 14845 SKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNG 14904
Query: 1583 GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ--TAVTNIDRPKGLAF 1640
K + + E T+ GL Y V A+N +G P + A+T D
Sbjct: 14905 RWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRD------- 14957
Query: 1641 TDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGL-------- 1692
DV+ IK+ + + + + D P + +D EL+G
Sbjct: 14958 -DVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIA 15016
Query: 1693 -------------RPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTD--LKFTQVTPTS 1737
R YT++ A + ++ + + P P + L T+VT
Sbjct: 15017 DFSTNLVNKDSTRRDSGAYTLT--ATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEK 15074
Query: 1738 LSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKY--- 1788
W PP ++ Y + K +T + N+A + + + V+ L+ +Y
Sbjct: 15075 CVLSWFPPLDDGGAKIDHY---IVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFR 15131
Query: 1789 --EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISW----RTKTETIT 1842
V+ Y + + L S P V PP+ VT T+ ++ + W I
Sbjct: 15132 VMAVNKYGVGEPLESEPVL-AVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEII 15190
Query: 1843 GFQVDAVPANGQTPIQRTIK--PDVRSYTITGLQPGTDYKIYLYTLNDNARSSP------ 1894
+ V+ GQ I+ K D+R Y ++GL G +Y+ + N S+P
Sbjct: 15191 NYIVERRDKAGQRWIKCNKKTLTDLR-YKVSGLTEGHEYEFRIMAENAAGISAPSPTSPF 15249
Query: 1895 -VVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVP 1949
D P N R L T+ +S+ ++W P + ITGY+++ P ++V
Sbjct: 15250 YKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVT 15309
Query: 1950 RPRP-GVTEATITGLEPGTEYTIYVIALKNNQKSEPLI 1986
P T TITGL EY I + A+ + EP +
Sbjct: 15310 PPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPAL 15347
Score = 121 bits (303), Expect = 9e-27
Identities = 287/1414 (20%), Positives = 508/1414 (35%), Gaps = 177/1414 (12%)
Query: 610 GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
GP E + T + WN P ++IS YI+ R + + W + + +Y
Sbjct: 18306 GPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLS-WTQVSTEVQALNY 18364
Query: 667 TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
+ L PG Y +++++ +YG E P+ S VT P ++
Sbjct: 18365 KVTKLLPGNEYIFRVMAVNKYGIGE-------------PLESGPVTACNPYKPPGPPSTP 18411
Query: 727 SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEP-----QYLDLPSTATSVNIPDLL 781
V+ IT S VV+W D G +E + E+ D+ + T + + L
Sbjct: 18412 EVSAITKDSMVVTWARPVDD-GGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLT 18470
Query: 782 PGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPP-DPTVDQVDDTSIVVRWSRP- 834
G Y N + E E S+ P PP +P V +S+ + WS+P
Sbjct: 18471 EGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPI 18530
Query: 835 ---QAPITGYRIVYSPSVEGSSTELNLPE--TANSVTLSDLQPGVQYNITIYAVEENQES 889
AP+ GY + + T P T++ L+ +YN I A+
Sbjct: 18531 YDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVG 18590
Query: 890 TPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK--------VTIMWTP-PE---SAVTGY 937
P + R + D +V ++ VTI P PE G
Sbjct: 18591 EPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGI 18650
Query: 938 RVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL 997
D + + + VT G Y + G ++ + +
Sbjct: 18651 LTDRAQIEVTSS------FTMLVIDNVTRFDSG--RYNLTLENNSGSKTAFVNVRVLDSP 18702
Query: 998 DAPTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPL 1053
AP NL +V + W PP A+IT Y + T R + + + +
Sbjct: 18703 SAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRI 18762
Query: 1054 RNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN------TEVTETTIVITW 1107
NLQ Y ++A + E TT S PP +VT T I W
Sbjct: 18763 ENLQEGCSYYFRVLA---SNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKW 18819
Query: 1108 T-PAPRIGFKLG----VRPSQGGEAPREVTS-DSGSIVVSGLTPGVEYVYTIQVLR---- 1157
P G K+ ++G E T + +SGLT G EYV+ + +
Sbjct: 18820 EKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGR 18879
Query: 1158 -DGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGY-RITTTPTNG 1215
D ++ P++ + + + P L V D+ R T
Sbjct: 18880 SDPRQLGVPVIARDIE-IKPSVELPFHT------FNVKAREQLKIDVPFKGRPQATVNWR 18932
Query: 1216 QQGNSLEEVVHADQSSC---TFDNLSPGLEYNVSVYTVKDDKES----VPISDTIIPAVP 1268
+ G +L+E + SS T ++ + +V Y + + VPI+ ++
Sbjct: 18933 KDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPG 18992
Query: 1269 PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAE---LSISPSDNA 1322
PP +R + D++ ++W PP ++N++V K E +S + + +
Sbjct: 18993 PPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVE----KKETTSTTWHIVSQAVARTS 19048
Query: 1323 VVLTNLLPGTEYVVSVSS-----VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTV 1376
+ + L G+EY V + ES+ + P G T ++ V
Sbjct: 19049 IKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLV 19108
Query: 1377 HWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN 1432
W P + + GY + + + +++ + + ++ L G Y + A N
Sbjct: 19109 TWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAEN 19168
Query: 1433 ----GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGE 1484
G+ D P EV T S+ + W P + Y + E
Sbjct: 19169 IAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRE 19228
Query: 1485 TGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEID 1543
++ ++ ++ L Y V+A S S I + +++
Sbjct: 19229 LPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVE 19288
Query: 1544 KPSQMQVTDVQDNSI--SVKWLPSSSPVTG--YRVTTTPKNG---PGPTKTKTAGPD-QT 1595
P M +D + + + L ++ + G V + K+G +T+ D T
Sbjct: 19289 PPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHT 19348
Query: 1596 EMTIEGL--QPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKG--LAFTDVDVDSIKIA 1651
+T++ + T +YV+++ +N +G V V + P L + + ++
Sbjct: 19349 LLTVKDCIRRDTGQYVLTL--KNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLS 19406
Query: 1652 WESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGE--EDTAELQGLRPGSEYTVSVVAL 1705
W PQ + Y V + H + +GE + ++ L G+EY V +
Sbjct: 19407 WGRPQEDGGADIDYYIV---EKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGV 19463
Query: 1706 HDDMESQPLIGTQSTAIPA---------PTDLKFTQVTPTSLSAQWTPP----NVQLTGY 1752
+ +PL +S AI A PT L+ T VT S++ W+ P +++GY
Sbjct: 19464 NKYGVGEPL---ESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGY 19520
Query: 1753 RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTT 1810
+ K ++ V +GL +YE VYA S P++ ++
Sbjct: 19521 IIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRA 19580
Query: 1811 LENV---SPPRRARVTDATETTITISWRTKT----ETITGFQVD---AVPANGQTPIQRT 1860
+ V SPP + ++ D+ +TTITI+W ITG+ V+ + + +T IQ
Sbjct: 19581 EDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSL 19640
Query: 1861 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP 1894
+ YTI+GL G +Y + ++N S P
Sbjct: 19641 RGTE---YTISGLTTGAEYVFRVKSVNKVGASDP 19671
Score = 120 bits (302), Expect = 1e-26
Identities = 326/1553 (20%), Positives = 547/1553 (35%), Gaps = 248/1553 (15%)
Query: 605 YPSSSGPVEVFITETPSQPNSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEA-TIP 660
Y P+ V IT+ S + W P+ + I+ Y++ R K S+ RW A T+
Sbjct: 6691 YDVPGPPLNVTITDVNRFGVS--LTWEPPEYDGGAEITNYVIELRDKTSI-RWDTAMTVR 6747
Query: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
S T+ V EGQ S + R S +TP E P P
Sbjct: 6748 AEDLSATVTD-----VVEGQEYSFRVRAQN---RIGVGKPSAATPFVKVADPIER-PSPP 6798
Query: 721 LVATSESVTEITASSFVVSWV----SASDTVSGFRVEYELSEEGDEPQY---LDLPSTAT 773
+ TS T+ SS + W + G+ +E EEG + + L T
Sbjct: 6799 VNLTSSDQTQ---SSVQLKWEPPLKDGGSPILGYIIER--CEEGKDNWIRCNMKLVPELT 6853
Query: 774 SVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV---DDTSIVVR 830
+ L G KY+ V ++ G TA DA +PT+D D ++V
Sbjct: 6854 -YKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIV- 6911
Query: 831 WSRP---QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSD-----LQPGVQYNITIYA 882
P P TGY + G L + TLS + P + + IY
Sbjct: 6912 -PNPITILVPSTGYPRPTATWCFGDKV-LETGDRVKMKTLSAYAELVISPSERSDKGIYT 6969
Query: 883 VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYR 938
++ + + + R +P++L+F ++T V + W PP+ S +TGY
Sbjct: 6970 LKLENRVKTISGEIDVNVIARPS---APKELKFGDITKDSVHLTWEPPDDDGGSPLTGYV 7026
Query: 939 VDVIPVNLPGEHGQRLPISRNTFAE-----------VTGLSPGVTYYFKVFAVSHGRESK 987
V ++ +SR T+ + V L G Y FKV A + +
Sbjct: 7027 V------------EKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGE 7074
Query: 988 PLTAQQTTKL-------DAPTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRR 1036
P + + D P N+++ + T +++ + W PP+ ++I GY V R
Sbjct: 7075 PAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGY--IVERCPR 7132
Query: 1037 GQPRQYNVGPSV--SKYPLRNLQPASEYTVSLVAIK-----------------GNQESPK 1077
G + G V +K + L+ Y + A+ QE+P+
Sbjct: 7133 GSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPE 7192
Query: 1078 ATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGF-KLGVRPSQGGEAPREVTSDSG 1136
+F ++ + + E +T P P+I + K + Q E
Sbjct: 7193 ---IFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKS 7249
Query: 1137 SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHL-EANPDTGVLTVSW 1195
++ + Y I+ + A + V+ PP + + ++ +LT +
Sbjct: 7250 TVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNP 7309
Query: 1196 ERST-TPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV-----YT 1249
R IT Y + T+ + + L V T L P EY V Y
Sbjct: 7310 PRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKAT--KLIPNKEYIFRVAAENMYG 7367
Query: 1250 VKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPV 1305
V + ++ PI+ P PPT L ++I D + +TW P +T + V
Sbjct: 7368 VGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDP 7427
Query: 1306 KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGID 1365
++ V + D + L +Y V + P + + + P
Sbjct: 7428 DTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPP 7487
Query: 1366 F-------SDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPR-EDRVPHSRNSI 1413
+ D+ S ++W P A I Y I R + VP +++
Sbjct: 7488 WPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH-- 7545
Query: 1414 TLTNLTPGTEYVVSIVALNGREES-------PLLIGQQSTVSDVPRDLEVVAATPTSLLI 1466
L L G EY + A+N ES P+L ++ PR LEV+ T + +
Sbjct: 7546 LLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADL 7605
Query: 1467 SWDAPAVTVRYYRITYGETGGNSPVQEFTVPG---------------SKSTATISGLKPG 1511
W P E G SP+ + V + T++ L G
Sbjct: 7606 KWTVP------------EKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEG 7653
Query: 1512 VDYTITVYAVTGRGDSPASSKPISINYR---TEIDKPSQMQVTDVQDNSISVKWLPSSS- 1567
Y V A G S + S+ + T P + V DV + +KW P +
Sbjct: 7654 SLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKND 7713
Query: 1568 ---PVTGYRVTTTPKNGPGPTKT-KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
P+ Y + + G K KTAGPD + ++ T E V A+N +G P
Sbjct: 7714 GGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGT-EVQFQVRAENEAGVGHP 7772
Query: 1624 LVQTAVTNIDRPKG-------LAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHEL 1676
T + +I+ P L TD I IAW+ P+ SP G H +
Sbjct: 7773 SEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPE-------KNGGSPIIGYH-V 7824
Query: 1677 FPAPDGEEDTAEL-------------QGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP 1723
P G E + +G+ P EY + V A++ S+P +++
Sbjct: 7825 EMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAK 7884
Query: 1724 APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLM 1783
P D K T T + + G ++ + + P+ ++ D V S +
Sbjct: 7885 DP-DCKPTIDLETH-------DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRL 7936
Query: 1784 VATKYEVSVYALKDTLTSRPAQGVVT-TLEN----------------VSPPRRARVTDAT 1826
+S + L+ + R G+ T TLEN P + + +D T
Sbjct: 7937 TMKNDHISAH-LEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDIT 7995
Query: 1827 ETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIY 1882
+++ ++W I + ++ A +T I + S+T+ L P +Y
Sbjct: 7996 KSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFR 8055
Query: 1883 LYTLND-------NARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARIT 1931
+ +N ++ + D D P ++ T ++ ++W+PP ++I
Sbjct: 8056 VKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIM 8115
Query: 1932 GYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
GYII+ G + + T GLE G EY V A SEP
Sbjct: 8116 GYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEP 8168
Score = 118 bits (296), Expect = 6e-26
Identities = 316/1543 (20%), Positives = 554/1543 (35%), Gaps = 238/1543 (15%)
Query: 607 SSSGPVEVFIT----ETPSQPNSHPIQWNAPQPSHISKYILRWRP---------KNSVGR 653
+SSG F+T +TP P + ++ + L W P KN V
Sbjct: 17602 NSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSA-----FLVWEPPIIDGGAKVKNYVID 17656
Query: 654 WKEATIPGHLN--------SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTP 705
+E+T + N S+ ++ L G +Y ++++ ++G P
Sbjct: 17657 KRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG-------------VGVP 17703
Query: 706 VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGD 761
V + P SP ++T+++ +S + W V G+ VE + +G
Sbjct: 17704 VETVDAVKAAEPPSP--PGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE--MQPKGT 17759
Query: 762 EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQ 821
E + S + + L G++Y V +E G+ + A D P++
Sbjct: 17760 EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKL 17819
Query: 822 VDDTSIVVRWS--RPQAPITGY-RIVYSPSVEGS----STELNLPETANSVTLSDLQPGV 874
+T + + + P+ G R S +G +T +N+ ETA S L ++ G
Sbjct: 17820 PFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLH-IKEGN 17878
Query: 875 QYNITIYAVEENQESTPV-----VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTP 929
+ + Y V + VI E G P ++F EV+ V I W P
Sbjct: 17879 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGP-------VRFDEVSADFVVISWEP 17931
Query: 930 PESA----VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE 985
P ++ Y V+ H ++R T ++T L G Y F++FA + +
Sbjct: 17932 PAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTI-KITKLKTGTEYQFRIFAENRYGK 17990
Query: 986 SKPLTA-----QQTTKLDAPTNLQFVNE-TDSTVLVRWTPP----RAQITGYRLTVGLTR 1035
S PL + Q K P FV + +LV+W P +I GY L
Sbjct: 17991 SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 18050
Query: 1036 RGQPRQYNVGP-SVSKYPLRNLQPASEYT--VSLVAIKGNQESPKATGVFTTLQPGSSIP 1092
+ N P +K+ L EY VS I G + K + F P P
Sbjct: 18051 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCD--P 18108
Query: 1093 PYNTE---VTETTIVITWT-PAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
P E +T + + W PA G K+ + + P G + + T +E
Sbjct: 18109 PGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLP------DGRWMKASFTNVLE 18162
Query: 1149 YVYTIQVLRDGQERDAPIVNK-VVTPLSPPT---------------NLHLEANPDTGVLT 1192
+T+ L + Q + ++ + S P+ N L+ ++
Sbjct: 18163 TEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVV 18222
Query: 1193 VSWERSTTP-DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLS---------PGLE 1242
+ E DI G I + + G LEE + T + G +
Sbjct: 18223 HAGETFVLEADIRGKPIPDVVWS-KDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18281
Query: 1243 YNVSVYTVKDDKESVPISDTIIPAVPPPTD-LRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301
Y + + V K S+PI+ ++ PP L+ T + + + W PP N
Sbjct: 18282 YILKLSNVGGTK-SIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHY 18340
Query: 1302 YSPVKNEEDVAELSISPSDNAV--VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1359
+ ++ +S A+ +T LLPG EY+ V +V + PL T +
Sbjct: 18341 IIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACN 18400
Query: 1360 S------PTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHS 1409
P+ + S IT +S V W P I GY + + + ++ +
Sbjct: 18401 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 18460
Query: 1410 RNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTV---SDVPRDLEVVAATPT 1462
+ +T LT G Y + A N G P + + P + +V + +
Sbjct: 18461 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRS 18520
Query: 1463 SLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-----------------TI 1505
S+ ++W P G +PV+ + V ++ A T+
Sbjct: 18521 SVSLAWSKPIYD------------GGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTV 18568
Query: 1506 SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPS 1565
+ LK +Y + A+ G ++ P S+ + I+ P D++ V L +
Sbjct: 18569 TKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLR----KVVVLRA 18624
Query: 1566 SSPVTGYRVTTTPKNGPGPT----KTKTAGPD--QTEMTIEGLQPTVEYVV-------SV 1612
S+ + R+ T K P P K + D Q E+T ++ V ++
Sbjct: 18625 SATL---RLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNL 18681
Query: 1613 YAQNPSGESQPLVQTAVTNI-DRPKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYS 1667
+N SG V V + P L +V DS+ ++WE P +++ Y V
Sbjct: 18682 TLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKR 18741
Query: 1668 SPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT- 1726
+ + + T ++ L+ G Y V+A ++ P T+ + P
Sbjct: 18742 ETTRKAYATI-TNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPL 18800
Query: 1727 ---DLKFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPK--EKTGPMKEINLAPDSSSV 1777
+ VT + + +W P ++TGY V + K EK ++ +
Sbjct: 18801 PPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVK----TLEA 18856
Query: 1778 VVSGLMVATKYEVSVYALKDTLTSRPAQ-GVVTTLENVS-------PPRRARVTDATETT 1829
+SGL +Y V A+ + S P Q GV ++ P V +
Sbjct: 18857 TISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLK 18916
Query: 1830 ITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ----PGTDYKIYLYT 1885
I + ++ + + ++ D GQT + T S T+T L D Y
Sbjct: 18917 IDVPFKGRPQATVNWRKD-----GQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELC 18971
Query: 1886 LNDNARSS--PVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEK 1939
++++A S P+ I P +R + +S+ +SW PP +I+ YI++ ++
Sbjct: 18972 VSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKE 19031
Query: 1940 PGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 1982
S +V + T I L G+EY V A KS
Sbjct: 19032 TTSTTWHIVSQ-AVARTSIKIVRLTTGSEYQFRVCAENRYGKS 19073
Score = 118 bits (295), Expect = 8e-26
Identities = 287/1359 (21%), Positives = 491/1359 (36%), Gaps = 205/1359 (15%)
Query: 780 LLPGRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP 834
++ G +YI VN Y I E E +++ + P P P V ++ S+ V WSRP
Sbjct: 20533 IIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRP 20592
Query: 835 QA----PITGYRIVYSPSVEGSSTEL---NLPETANSVTLSDLQPGVQYNI-TIYAVEEN 886
A I+GY + ++ + +T VT QY + + A +
Sbjct: 20593 IADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQG 20652
Query: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVI 942
S P + D P ++ + T +T+ W+ P SAVTGY V++
Sbjct: 20653 PFSEP---SEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEI- 20708
Query: 943 PVNLPGEHGQRLPIS-----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK- 996
GE + +S R T V+ L PGV YYF+V AV+ + +P+ + +
Sbjct: 20709 ---RQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQA 20765
Query: 997 ---LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--------RQYNVG 1045
L+AP E D V +R T A+ G + V + +G+P + N+G
Sbjct: 20766 KDILEAP-------EIDLDVALR-TSVIAK-AGEDVQVLIPFKGRPPPTVTWRKDEKNLG 20816
Query: 1046 PSVSKYPLRNLQPASEYTVS----------LVAIKGNQESPKATGVFTTL--QPGSSIPP 1093
S ++Y + N +S T+ ++ I+ PK++ V + P +
Sbjct: 20817 -SDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKL 20875
Query: 1094 YNTEVTETTIVITWTP------APRIGFKLGVRPS---QGGEAPREVTSDSGSIV-VSGL 1143
V+ T+ + W P +P I + + R + + +S S ++ +S
Sbjct: 20876 QVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEK 20935
Query: 1144 TPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDI 1203
TP V + G+ + K +P +L ++ + T V+ +SW T PD
Sbjct: 20936 TPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVI-LSW---TKPDF 20991
Query: 1204 TGYRITTTPTNGQQGNSLEEVVHADQS-SCTFD----NLSPGLEYNVSVYTVKDDKESVP 1258
G + T ++G + HA S +C + LE+ V K + V
Sbjct: 20992 DGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVT 21051
Query: 1259 ISDTIIP--AVPPPTDLRFTNIGPDTMRV----------TWAPPPSIDLTNFLVRYSPVK 1306
I + + P DL T+R+ P PSI ++L P+K
Sbjct: 21052 IGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSI---SWLKDGLPLK 21108
Query: 1307 NEEDVAELSISPSDNAVVLT----NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1362
E V S ++N + L+ G +Y V + + + P+ P
Sbjct: 21109 ESEFV---RFSKTENKITLSIKNAKKEHGGKYTVILDNAV-CRIAVPITVITLGPPSKPK 21164
Query: 1363 G-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
G I F +I A+S + W P IT Y I E + +R + + N
Sbjct: 21165 GPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKR-ETSQTNWKMVCSSVARTTFKVPN 21223
Query: 1418 LTPGTEYVVSIVALNGREESPLLIG------QQSTVSDVPRDLEVVAATPTSLLISWDAP 1471
L EY + A N S L+ Q + P + T + ++WDAP
Sbjct: 21224 LVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAP 21283
Query: 1472 AV----TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
V + + E + T P S +GL G+DY VYA G S
Sbjct: 21284 VYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLS 21343
Query: 1528 PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPG 1583
S + +D P DV +I++KW P S + GY + N
Sbjct: 21344 SPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERW 21403
Query: 1584 PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN------PSGESQPLVQTAVTNIDRPKG 1637
+ + + T+ GL P Y + A+N P +S ++ T N+ P
Sbjct: 21404 -VRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENV--PPI 21460
Query: 1638 LAFTDVDVDSI--------------------KIAWESPQGQVSRYRVTYSSPEDGIHELF 1677
+ F D + ++ W ++ + + G LF
Sbjct: 21461 VEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLF 21520
Query: 1678 PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTS 1737
+ T + +G+ YTV +++ + Q T ++FT +T
Sbjct: 21521 V----RDATRDHRGV-----YTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEK 21571
Query: 1738 LSAQWTPP-NVQLTGYRVRVTPKEKTGPM--KEINLAPDSSSVVVSGLMVATKYEVSVYA 1794
++ W P N + K +T + I ++ S L+ +Y+ V A
Sbjct: 21572 MTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSA 21631
Query: 1795 LKDTLTSRP--AQGVVTTLENVSP--PRRARVTDATETTITISWRTKTETITGFQVDA-- 1848
+ RP + VV ++ P P ++ T +IT++W + E+ G ++
Sbjct: 21632 VNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTW-ARPESDGGSEIQQYI 21690
Query: 1849 -----------VPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1897
V + PI T + +TGL G +Y+ ++ + +NA
Sbjct: 21691 LERREKKSTRWVKVISKRPISET------RFKVTGLTEGNEYEFHV--MAENAAGVGPAS 21742
Query: 1898 DASTAIDA---------PSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPP 1944
S I P+ ++ T+ ++ + W P I GYII+ K
Sbjct: 21743 GISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGD 21802
Query: 1945 REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 1983
V T T+T L+ G EY V A+ K +
Sbjct: 21803 WHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGD 21841
Score = 117 bits (293), Expect = 1e-25
Identities = 324/1541 (21%), Positives = 541/1541 (35%), Gaps = 222/1541 (14%)
Query: 612 VEVFITETPSQPNSHPIQ----------WNAPQP---SHISKYILRWRPKNSVGRWKEAT 658
VEV + + P P + I WN P+ S I+ Y++ R +S W + +
Sbjct: 7279 VEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEV-WHKLS 7337
Query: 659 IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
++ L P Y ++ + YG E PV ++ +T +
Sbjct: 7338 STVKDTNFKATKLIPNKEYIFRVAAENMYGVGE-------------PVQASPITAKYQFD 7384
Query: 719 SPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATS 774
P T ++IT + ++W D ++G+ VE + + +P T+
Sbjct: 7385 PPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTT 7444
Query: 775 VNIPDLLPGRKYIVNVY--QISEDGEQSL----ILSTSQTTAPDAPPDPTVDQVDDTSIV 828
+ L +KY V ++ G+ S IL P P PTV V TS+
Sbjct: 7445 YRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVR 7504
Query: 829 VRWSRPQ----APITGY--RIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA 882
+ W++P+ A I Y ++ + + E +P T + L L G +Y+ + A
Sbjct: 7505 LNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH--LLPGLMEGQEYSFRVRA 7562
Query: 883 VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYR 938
V + ES P + PR L+ + +T + WT PE S +T Y
Sbjct: 7563 VNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYI 7622
Query: 939 VDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH-GR------ESKPLTA 991
V+ V G + ++T VT L+ G Y F+V A + G+ E L
Sbjct: 7623 VEKRDVRRKGWQTVDTTV-KDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAK 7681
Query: 992 QQTTKLDAPTNLQFVNETDSTVLVRWTPPR--AQITGYRLTVGLTRRGQPRQYNVGPSVS 1049
T P L V+ T V ++W PP+ R + R R G +
Sbjct: 7682 DTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAG 7741
Query: 1050 KYPLRNLQPASEYTVSLVAIKGNQES-----PKATGVFTTLQPGS-SIPPYNTEVTET-- 1101
+ E T ++ E+ + T + + P S PP + VT+
Sbjct: 7742 PDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGR 7801
Query: 1102 -TIVITWTP------APRIGFKLGVRPSQGGEAPREVTS----DSGSIVVSGLTPGVEYV 1150
I I W P +P IG+ + + P G E V S D V G+ P EYV
Sbjct: 7802 KHIAIAWKPPEKNGGSPIIGYHVEMCP-VGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYV 7860
Query: 1151 YTIQVLRD-GQERDAPIVNKVVT--PLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYR 1207
++ + G + I VV P PT + LE + ++ + E+ + P +R
Sbjct: 7861 LRVRAVNAIGVSEPSEISENVVAKDPDCKPT-IDLETH---DIIVIEGEKLSIP--VPFR 7914
Query: 1208 ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY------NVSVYTV----KDDKESV 1257
PT + +EV +D+ + D++S LE + +YT+ K +
Sbjct: 7915 AVPVPTVSWHKDG-KEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATA 7973
Query: 1258 PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSIS 1317
I+ +I P D++ ++I + ++TW PP T L + + +
Sbjct: 7974 SINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVM 8033
Query: 1318 PSDNAVVLT--NLLPGTEYVVSVSSV-------YEQHESTPLRGRQKTGLDSPTGIDFSD 1368
+N + T +L+P EY V +V Y + ++ + K D P ++ +
Sbjct: 8034 SGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHN 8093
Query: 1369 ITANSFTVHWIAP----RATITGYRIRH--HPEHFSGRPREDRVPHSRNSITLTNLTPGT 1422
TA + T+ W P + I GY I E R E VP + T L G
Sbjct: 8094 PTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPIL--TYTAKGLEEGK 8151
Query: 1423 EYVVSIVALNGREESPLLIGQQSTVSDVPRDL-EVVAATPTSLL----ISWDAPAVTVRY 1477
EY + A N S T + P D +V+ T + I+ DA Y
Sbjct: 8152 EYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPY 8211
Query: 1478 YRITY------------------------GETGGNSP-----VQEFTVPGSKSTATISGL 1508
IT+ GE P Q ++ SK + +
Sbjct: 8212 PTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRV 8271
Query: 1509 KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP---- 1564
+ + +Y + D + P +++ P D++ S+ KW P
Sbjct: 8272 RDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDD 8331
Query: 1565 SSSPVTGYRVTTTPKNGP-GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
S + Y + K P T+ + ++ L EY+ V A+N G P
Sbjct: 8332 GGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPP 8391
Query: 1624 LVQTAVT------NIDRPKGLAFTDVDVDSIKIAWESPQ-------GQVSRYRVTYSSPE 1670
V + D P DV +S+ + W P+ G R S+
Sbjct: 8392 CVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHW 8451
Query: 1671 DGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD------DMESQPLIGTQSTAIPA 1724
+++ A + GL G Y V A + S P + P
Sbjct: 8452 SRVNKSLL----NALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPG 8507
Query: 1725 PTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV--- 1777
P + T + T++ +W PP ++ GY V K+ G + V
Sbjct: 8508 PPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFV---DKQLVGTNEWSRCTEKMIKVRQY 8564
Query: 1778 VVSGLMVATKYEVSVYALKDTLTSRPAQ-GVVTTLENVSPPRRARVTDATETTITISWRT 1836
V + Y++ V A+ P + VT E PP A E +++
Sbjct: 8565 TVKEIREGADYKLRVSAVNAAGEGPPGETQPVTVAEPQEPP-------AVELDVSVKGGI 8617
Query: 1837 KTETITGFQVDAVPANGQTPIQRTIKPD--------------VRSYTITGLQPGTDYKIY 1882
+ ++ AV P + K + +S I D+ Y
Sbjct: 8618 QIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRY 8677
Query: 1883 LYTLNDNARSSPVVIDASTAIDAPS---NLRFLATTPNSLLVSWQPPR----ARITGYII 1935
+ T N+ S D P +L+ + T L++W P + ITG+II
Sbjct: 8678 VITAT-NSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFII 8736
Query: 1936 KYEKPGSPP-REVVPRPRPGVTEATITGLEPGTEYTIYVIA 1975
+ + R+ + R ++ ITGL G EY VIA
Sbjct: 8737 ERKDAKMHTWRQPIETER---SKCDITGLLEGQEYKFRVIA 8774
Score = 117 bits (293), Expect = 1e-25
Identities = 292/1326 (22%), Positives = 488/1326 (36%), Gaps = 202/1326 (15%)
Query: 811 PDAPPDPT-VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSV 865
P P P + V + + W P+ + IT Y I + + ++ +
Sbjct: 9720 PGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTY 9779
Query: 866 TLSDLQPGVQYNITIYAVEENQESTPVVIQQETT-------GTPRSDTVPSPRDLQFVEV 918
T+ L G +Y I A + P+ + ET G P TV S V
Sbjct: 9780 TIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSS--------V 9831
Query: 919 TDVKVTIMWTPPE----SAVTGYRVDVIPVNLPG-EHGQRLPISRNTFA---EVTGLSPG 970
T +T+ W PE S VTGY +++ + R PI T +VTGL G
Sbjct: 9832 TRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEG 9891
Query: 971 VTYYFKVFAVSHGR------ESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR--- 1021
Y F+V+A++ S P TA+ P + + T S+ + W+PP
Sbjct: 9892 SDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDG 9951
Query: 1022 -AQITGYRLTVGLTRRGQPRQYNVGPSV----SKYPLRNLQPASEYT--VSLVAIKGNQE 1074
+++TGY V G+ ++ G +K + L+ + Y V V I G E
Sbjct: 9952 GSKVTGY--IVEYKEEGK-EEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGE 10008
Query: 1075 SPKATGVFTT--------LQPGSSIPP----YNTEVTETTIVITWTPAPRIGFKLGVRPS 1122
+ T V LQ +S+ + V ++ P P + + + R +
Sbjct: 10009 PGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNER-T 10067
Query: 1123 QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT---PLSPPTN 1179
EA E T+ S S+V+ + VY++ + ER I+ V+ P+ P
Sbjct: 10068 LPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFL 10127
Query: 1180 LHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239
H N + S E IT Y I ++ + + V + + T L
Sbjct: 10128 AHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTV--TRQNATVQGLIQ 10185
Query: 1240 GLEY--------NVSVYTVKDDKESVPISDTIIPAVPP-PTDLRFTNIGPDTMRVTWAPP 1290
G Y ++ + + E++ I + I VP P DL + +T+ +TW PP
Sbjct: 10186 GKAYFFRIAAENSIGMGPFVETSEALVIREPI--TVPERPEDLEVKEVTKNTVTLTWNPP 10243
Query: 1291 P---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHES 1347
++ N+++ + E+ + + + L G Y VS+V +
Sbjct: 10244 KYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQG 10303
Query: 1348 TPLRGRQ----KTGLDSPT-GIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPR 1402
P + K L PT +DF D T+ + +TG +SG+P+
Sbjct: 10304 KPSFCTKPITCKDELAPPTLHLDFRD----KLTIR-VGEAFALTG--------RYSGKPK 10350
Query: 1403 ------EDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQST--------VS 1448
+D + T TP T + I A ++ + ST V+
Sbjct: 10351 PKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVN 10410
Query: 1449 DVPRDLEVVA------ATPTSLLISWDAP----AVTVRYYRITYGETGGN--SPVQEFTV 1496
V R V T ++ISW P + Y I E G + PV T
Sbjct: 10411 VVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPV---TS 10467
Query: 1497 PGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEI-DKPSQMQVTDVQ 1554
+K+T +S L G DY ++A G S P S + R + D P Q VT+V
Sbjct: 10468 ASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVT 10527
Query: 1555 DNSISVKWLP---SSSPVTGY---RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEY 1608
+S V W P+T Y + T K TK T+ + L +Y
Sbjct: 10528 KDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIH--PYTKFRVPDLLEGCQY 10585
Query: 1609 VVSVYAQN------PSGESQPL-VQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQ----G 1657
V A+N PS S+P+ + + P D +S+ + W+ P+
Sbjct: 10586 EFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGS 10645
Query: 1658 QVSRYRVTYSSPEDGI-HELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLI 1715
++ Y V Y D P+ +T ++ GLR G Y V+A++ ES P
Sbjct: 10646 KILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDP-- 10703
Query: 1716 GTQSTAIPAPTDLKFTQVTP-TSLSAQWTPPNVQLTGYRVRVT------PKEKTGPMKEI 1768
+P P +K P L A G +R++ P K KE
Sbjct: 10704 ----AHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKED 10759
Query: 1769 NLAPDSSSVVVSGLMVATKYEV--------SVYAL--KDTLTSRPAQGVVTTLENVSPPR 1818
AP + + V+ V +K E+ +Y+L ++ S+ V L+ PPR
Sbjct: 10760 RDAPTKARIDVT--PVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPR 10817
Query: 1819 RARVTDATETTITISWRTKTE----TITGFQVDA--VPANGQTPIQRTIKPDVRSYTITG 1872
V++ + + ++W+ + IT + V+ V + +P+ T K +S+
Sbjct: 10818 DLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKK--KSHFAKH 10875
Query: 1873 LQPGTDYKIYLYTLNDNARSSPV-------VIDASTAIDAPSNLRFLATTPNSLLVSWQP 1925
L G Y + N R V +D P +L + + + W
Sbjct: 10876 LNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNK 10935
Query: 1926 P----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 1981
P + ITGY+++Y++ G+ ++ + E +TGL+ G Y V K
Sbjct: 10936 PDRDGGSPITGYLVEYQEEGT--QDWIKFKTVTNLECVVTGLQQGKTYRFRV-------K 10986
Query: 1982 SEPLIG 1987
+E ++G
Sbjct: 10987 AENIVG 10992
Score = 112 bits (281), Expect = 3e-24
Identities = 265/1361 (19%), Positives = 500/1361 (36%), Gaps = 176/1361 (12%)
Query: 766 LDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT 825
+D + TS I + G K + ++ G+ ++ P + V + D
Sbjct: 6548 IDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDG 6607
Query: 826 SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPG-VQYNIT 879
+ + W P + I GY +V ++ + L + T++ LQ G V+Y
Sbjct: 6608 EVSLAWEEPLTDGGSKIIGY-VVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFR 6666
Query: 880 IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVT 935
+ A PV + D P ++ +V V++ W PPE + +T
Sbjct: 6667 VSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEIT 6726
Query: 936 GYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT 995
Y +++ + + A VT + G Y F+V A + KP A
Sbjct: 6727 NYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFV 6786
Query: 996 KL-------DAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR---- 1040
K+ P NL ++T S+V ++W PP + I GY + G+
Sbjct: 6787 KVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGY--IIERCEEGKDNWIRC 6844
Query: 1041 QYNVGPSVSKYPLRNLQPASE--YTVSLVAIKGNQESPKATGVFTT----LQPGSSIPPY 1094
+ P ++ Y + L+ ++ Y VS G + + G T ++P + +
Sbjct: 6845 NMKLVPELT-YKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAF 6903
Query: 1095 NTEV-----TETTIVI--TWTPAPRIGFKLGVRPSQGGEAPREVT-SDSGSIVVSGLTPG 1146
+ TI++ T P P + G + + G+ + T S +V+S
Sbjct: 6904 KDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERS 6963
Query: 1147 VEYVYTIQVLRDGQERDAPI-VNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD--- 1202
+ +YT+++ + I VN + P +P + D+ LT WE PD
Sbjct: 6964 DKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLT--WE---PPDDDG 7018
Query: 1203 ---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY--NVSVYTVKDDKESV 1257
+TGY + + + + + V T +L G EY V E
Sbjct: 7019 GSPLTGYVVEKREVSRKTWTKVMDFV--TDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7076
Query: 1258 PISDTIIPAVP-----PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEE 1309
+ + + + P PP ++++ + +++ +TW PP + + ++V P +++
Sbjct: 7077 YVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDK 7136
Query: 1310 DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDI 1369
VA ++ + +T L G Y V ++ Q S P R ++ +D +
Sbjct: 7137 WVA-CGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEI-----QAVDTQEA 7190
Query: 1370 TANSFTVHWIAPRATITGYRIRHHPEHFSGRP-------REDRVPHSRNSITLTNLTPGT 1422
V +A G +I P +G+P + D + IT+ N+
Sbjct: 7191 PEIFLDVKLLAGLTVKAGTKI-ELPATVTGKPEPKITWTKADMILKQDKRITIENVP--K 7247
Query: 1423 EYVVSIVALNGREESPLLI------GQQSTVSDV--------PRDLEVVAATPTSLLISW 1468
+ V+IV + +I G+ + V +V P ++ T S L++W
Sbjct: 7248 KSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTW 7307
Query: 1469 DAP----AVTVRYYRITYGETGG------NSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
+ P + Y + T +S V++ +K L P +Y V
Sbjct: 7308 NPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATK-------LIPNKEYIFRV 7360
Query: 1519 YAVTGRG-DSPASSKPISINYRTE-IDKPSQMQVTDVQDNSISVKWL----PSSSPVTGY 1572
A G P + PI+ Y+ + P++++ +D+ +++++ W SP+TGY
Sbjct: 7361 AAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGY 7420
Query: 1573 RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LV 1625
V + + T ++GL +Y V A+N +G +P L+
Sbjct: 7421 WVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILI 7480
Query: 1626 QTAVTNIDRPKGLAFTDVDVDSIKIAWESPQ--GQVSRYRVTYSSPEDGIHELFPAPDGE 1683
+ + P DV S+++ W P+ G + G E +G
Sbjct: 7481 KDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGV 7540
Query: 1684 EDTAE-LQGLRPGSEYTVSVVALHDDMESQ------PLIGTQSTAIPAPTD-LKFTQVTP 1735
T L GL G EY+ V A++ ES+ P++ + P+P L+ +T
Sbjct: 7541 PTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITK 7600
Query: 1736 TSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS 1791
+ +WT P +T Y V + G + ++ + V+ L E S
Sbjct: 7601 NTADLKWTVPEKDGGSPITNYIVEKRDVRRKG-WQTVDTTVKDTKCTVTPLT-----EGS 7654
Query: 1792 VYALKDTLTSRPAQGVVTTLEN----------VSPPRRARVTDATETTITISWRTKT--- 1838
+Y + + Q T +E+ PP V D T+ + + W
Sbjct: 7655 LYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDG 7714
Query: 1839 -ETITGFQVDAVPANGQTPIQ--RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP- 1894
I + ++ G ++ +T PD ++ +T + GT+ + + N+ P
Sbjct: 7715 GRPIQRYVIEKKERLGTRWVKAGKTAGPDC-NFRVTDVIEGTEVQFQVRAENEAGVGHPS 7773
Query: 1895 ------VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPP 1944
+ D ++ P +L + ++W+PP + I GY ++ G+
Sbjct: 7774 EPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEK 7833
Query: 1945 -REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
V RP + G+ P EY + V A+ SEP
Sbjct: 7834 WMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEP 7874
Score = 107 bits (266), Expect = 2e-22
Identities = 292/1356 (21%), Positives = 513/1356 (37%), Gaps = 189/1356 (13%)
Query: 727 SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQ--YLDLPSTA--TSVNIPDLLP 782
+VTE+T+ V+SW D G ++++ + ++ + + + ++ S T + + LL
Sbjct: 15066 AVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 15124
Query: 783 GRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAP 837
G +YI VN Y + E E +L+ + PD P +P V + S+VV W P +
Sbjct: 15125 GNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDS- 15183
Query: 838 ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ-------PGVQYNITIYAVEENQEST 890
G + + VE N TL+DL+ G +Y I A S
Sbjct: 15184 -DGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISA 15242
Query: 891 PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNL 946
P P + + ++ + ++I W P S +TGY V++ L
Sbjct: 15243 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIA---L 15299
Query: 947 PGEHGQRLPIS----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD---A 999
P E ++ + T +TGL+ Y +++A++ +P T K +
Sbjct: 15300 PEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRML 15359
Query: 1000 PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR---QYNVGPSVSKYPLRNL 1056
P ++ + V +R RL V + R P + G S+ K ++
Sbjct: 15360 PPEIELDADLRKVVTIR------ACCTLRLFVPIKGRPAPEVKWARDHGESLDK---ASI 15410
Query: 1057 QPASEYTVSLVAIKGNQESPK----------ATGVFTTLQ----PGSSIPPYNTEVTETT 1102
+ S YT+ +V +S K + F ++ PG EVT+T+
Sbjct: 15411 ESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTS 15470
Query: 1103 IVITWTPAPRI--GFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQ 1154
+ +TW P P + G K+ + E+ R+ S S V L G Y + +
Sbjct: 15471 VTLTWDP-PLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYF--R 15527
Query: 1155 VLRDGQ------ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITG 1205
VL + + A V PL P ++ ++ +++SWE+ I G
Sbjct: 15528 VLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNS--VSLSWEKPEHDGGSRILG 15585
Query: 1206 YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKE-SVPI 1259
Y I T G + V +++ T L G EY+ V + D ++ SVP+
Sbjct: 15586 Y-IVEMQTKGSDKWATCATVKVTEATIT--GLIQGEEYSFRVSAQNEKGISDPRQLSVPV 15642
Query: 1260 --SDTIIPAVPPPTDLRFTNIGPDTMRV----TWAPPPSIDLTNFLVRYSPVKNEEDVAE 1313
D +IP FT + + ++V P P++ V P+K
Sbjct: 15643 IAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNV---PLK---QTTR 15696
Query: 1314 LSISPSDNAVVLTNLLPGTE----YVVSV-SSVYEQHESTPLRGRQKTGLDSPTG-IDFS 1367
++ ++N +LT E YVV + +S E E+ + K G PTG +
Sbjct: 15697 VNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG--PPTGPVKMD 15754
Query: 1368 DITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423
++TA+S T+ W P+ ++I Y + + + + +R +I L G E
Sbjct: 15755 EVTADSITLSWGPPKYDGGSSINNYIVEKR-DTSTTTWQIVSATVARTTIKACRLKTGCE 15813
Query: 1424 YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPT-------SLLISWDAP----A 1472
Y I A N +S L + TV+ P + TP S+ + W+ P
Sbjct: 15814 YQFRIAAENRYGKSTYL-NSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGG 15872
Query: 1473 VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSK 1532
V Y + E V+ P ++ +GL+ GV+Y V A G S
Sbjct: 15873 SRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKV 15932
Query: 1533 PISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTK 1588
R D P + + V NS++++W S +TGY V K
Sbjct: 15933 SECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKAS 15992
Query: 1589 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-SQPLVQT-AVTNIDR--PKGLAFTDVD 1644
T + GL Y V A+N +G S+P T A+T D P ++
Sbjct: 15993 FTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKY 16052
Query: 1645 VDSIKI-AWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVV 1703
D+I + A ES + Y P I + G+++ + L S + +
Sbjct: 16053 KDTIVVHAGESFKVDAD----IYGKPIPTIQWI----KGDQELSNTARLEIKSTDFATSL 16104
Query: 1704 ALHDD---------MESQPLIGTQSTAI-------PAPTD--LKFTQVTPTSLSAQWTPP 1745
++ D ++++ + G +S + P P + + + VT + W PP
Sbjct: 16105 SVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPP 16164
Query: 1746 NVQLTGYRV--RVTPKEKTGPM--KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1801
+Q G + + + +T + ++ + S V+ L+ +Y + A+
Sbjct: 16165 -LQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVG 16223
Query: 1802 RPAQGVVTTLEN--VSP--PRRARVTDATETTITISWRTKT----ETITGFQVDAVPANG 1853
P + +N V P P+ VT T+ ++ + W I G+ ++ G
Sbjct: 16224 EPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEG 16283
Query: 1854 --QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDA-STAID------ 1904
T + + ++R +TGL DY+ + N S P A A D
Sbjct: 16284 IRWTRCHKRLIGELR-LRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPG 16342
Query: 1905 APSNLRFLATTPNSLLVSWQPP----RARITGYIIK 1936
P+N + + T +S+ +SW P I GYI++
Sbjct: 16343 PPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVE 16378
Score = 106 bits (265), Expect = 2e-22
Identities = 338/1705 (19%), Positives = 582/1705 (34%), Gaps = 213/1705 (12%)
Query: 606 PSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGH 662
P GPVE+ + + W P S I YIL R + + W +
Sbjct: 13976 PGPPGPVEI----SNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRL-LWTVVSEDIQ 14030
Query: 663 LNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLV 722
+ L G Y ++ ++ YG E PV S V P
Sbjct: 14031 SCRHVATKLIQGNEYIFRVSAVNHYGKGE-------------PVQSEPVKMVDRFGPPGP 14077
Query: 723 ATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778
V+ +T ++ VSW D ++G+ VE + + + P + +
Sbjct: 14078 PEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVT 14137
Query: 779 DLLPGRKYIVNVYQISEDG------EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS 832
L G Y V + G +L P P +P V S + W
Sbjct: 14138 GLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWG 14197
Query: 833 RPQ----APITGYRIVYSPSVEGSSTELNLPETANSVT---LSDLQPGVQYNITIYAVEE 885
+P ITGY +V V + + TA +T + DLQ +YN I A+ +
Sbjct: 14198 KPHYDGGLEITGY-VVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAIND 14256
Query: 886 NQESTPVVIQQ-ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPV 944
P VI E + +L+ V ++I P V
Sbjct: 14257 AGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKD 14316
Query: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYF--KVFAVSHGRESKPLTAQQTTKLDAP-- 1000
N+ ++ + NT + + P Y K K LD P
Sbjct: 14317 NINLKNRANI---ENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGP 14373
Query: 1001 -TNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSK-----YPLR 1054
NL+ + T +V + W P G R+T + + + + + + +K Y +
Sbjct: 14374 VLNLRPTDITKDSVTLHWDLPLID-GGSRITNYIVEKREATRKSYSTATTKCHKCTYKVT 14432
Query: 1055 NLQPASEYTVSLVAIK--GNQESPKATGVFTTLQPGSSIPPYNT-EVTETTIVITWTPAP 1111
L EY ++A G E + T + S N ++T++T+ + W P P
Sbjct: 14433 GLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAW-PKP 14491
Query: 1112 R-------IGFKLGVRPSQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVL----RDG 1159
+ G+ + + +G + +T+ G VV LT G EY + + + R
Sbjct: 14492 KHDGGSKITGYVIEAQ-RKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSA 14550
Query: 1160 QERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE--RSTTPDITGYRITTTPTNGQQ 1217
P++ K T L L L V+ + + + P + + T T G Q
Sbjct: 14551 PRESRPVIVKEQTMLP---ELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQ 14607
Query: 1218 G-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAV-----PPPT 1271
+ V ++ T N++ + + Y + + D I V PP
Sbjct: 14608 ILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTG 14667
Query: 1272 DLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNL 1328
++F + D + +W PP + + ++N++V + V EL+ + T L
Sbjct: 14668 PIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWV-ELATTVIRTTYKATRL 14726
Query: 1329 LPGTEYVVSVSS-----VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAP- 1381
G EY V + V S + + P G + +T +S T+ W P
Sbjct: 14727 TTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPL 14786
Query: 1382 ---RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------ 1432
+ I GY + + + N + LT G Y ++A N
Sbjct: 14787 SDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSK 14846
Query: 1433 -GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1491
+ P+L P L + T T + W P T + +Y + P
Sbjct: 14847 PSKPSEPMLALDPIDPPGKPVPLNITRHTVT---LKWAKPEYTGGFKITSYIVEKRDLPN 14903
Query: 1492 QEFTVPG----SKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPS 1546
+ ++ T+SGL Y V A G SP S +I R +++ P
Sbjct: 14904 GRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPK 14963
Query: 1547 QMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTK------TKTAGPDQTEMTIE 1600
+D I +R+ P PT + G + E+ I
Sbjct: 14964 IKVDVKFKDTVI-------LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIA 15016
Query: 1601 GLQPTV---------EYVVSVYAQNPSGESQPLVQTAVTNIDRP----KGLAFTDVDVDS 1647
+ ++ A NP G ++ + V +DRP LA T+V +
Sbjct: 15017 DFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKV--LDRPGPPEGPLAVTEVTSEK 15074
Query: 1648 IKIAWESP---QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVA 1704
++W P G + + + A + + ++ L G+EY V+A
Sbjct: 15075 CVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMA 15134
Query: 1705 LH-----DDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPPN----VQLTGYRV 1754
++ + +ES+P++ P P + + T +T S+ W P+ ++ Y V
Sbjct: 15135 VNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIV 15194
Query: 1755 RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYA-----LKDTLTSRPAQGVVT 1809
K +K VSGL +YE + A + + P
Sbjct: 15195 ERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACD 15254
Query: 1810 TLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVD-AVPANGQTPIQRTIKP- 1863
T+ PP RV D + ++I+I+W ITG+ V+ A+P + I + P
Sbjct: 15255 TVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQI---VTPP 15311
Query: 1864 ---DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAS---------TAIDAPSNLRF 1911
SYTITGL +YKI +Y +N P ++ + I+ ++LR
Sbjct: 15312 AGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRK 15371
Query: 1912 LATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTI 1971
+ T + P +K+ + + I G +
Sbjct: 15372 VVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLIVGNVNRFDSGK 15431
Query: 1972 YVIALKNNQKSEPLIGRKKTDELP--------QLVTLPHPNL-HGPEILDVPSTVQKTPF 2022
Y++ ++N+ S+ + + P + VT L P +LD S ++ +
Sbjct: 15432 YILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKN--Y 15489
Query: 2023 VTHPGYDTGNGIQLPGTSGQQPS--VGQQM--------IFEEHGFRRTTPPTTATPIRHR 2072
+ T T+ + S V Q + E+ + P TA ++
Sbjct: 15490 IVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKAS 15549
Query: 2073 PRPYPPNVGQEALSQTT-----ISW-APFQDTSE----YIISCHPVGTDEEPLQFRVPGT 2122
RP PP G+ L T +SW P D YI+ G+D+ V
Sbjct: 15550 ERPLPP--GKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATV--K 15605
Query: 2123 STSATLTGLTRGATYNIIVEALKDQ 2147
T AT+TGL +G Y+ V A ++
Sbjct: 15606 VTEATITGLIQGEEYSFRVSAQNEK 15630
Score = 106 bits (264), Expect = 3e-22
Identities = 321/1571 (20%), Positives = 563/1571 (35%), Gaps = 259/1571 (16%)
Query: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWR 646
YG G+ +P++ P V + + N+ I+W P+ S I+ Y++ +
Sbjct: 18781 YGIGLPAETTEPVKVSEPPLPPGRVTLVDVTR--NTATIKWEKPESDGGSKITGYVVEMQ 18838
Query: 647 PKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPV 706
K S +W T L + TI GL G Y ++ ++ + G + + PV
Sbjct: 18839 TKGSE-KWSTCTQVKTLEA-TISGLTAGEEYVFRVAAVNEKGRSDPRQL-------GVPV 18889
Query: 707 TSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL 766
+ + E P L + +V V + +R + + +E +
Sbjct: 18890 IARDI--EIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVN-V 18946
Query: 767 DLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDP---TVDQVD 823
T TS++I + K V Y++ I D P P +D+V
Sbjct: 18947 SSSKTVTSLSIKE---ASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVS 19003
Query: 824 DTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNIT 879
SI + W+ P+ I+ Y + + + ++ S+ + L G +Y
Sbjct: 19004 CDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFR 19063
Query: 880 I-----YAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE--- 931
+ Y ES+ VV + P S P P + V T + + W P
Sbjct: 19064 VCAENRYGKSSYSESSAVVAEY-----PFSPPGP-PGTPKVVHATKSTMLVTWQVPVNDG 19117
Query: 932 -SAVTGYRVDVIP-VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA---VSHGRES 986
S V GY ++ ++ ++ I+ +T +V+GL G+ Y ++V+A G+ S
Sbjct: 19118 GSRVIGYHLEYKERSSILWSKANKILIA-DTQMKVSGLDEGLMYEYRVYAENIAGIGKCS 19176
Query: 987 K---PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR----AQITGY-----RLTVG-- 1032
K P+ A+ D P + N T +V ++W+ P A+ITGY L G
Sbjct: 19177 KSCEPVPARDPC--DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRW 19234
Query: 1033 --------------LTRRGQPRQY-------NVGPSVSKYPLRNLQPASEYTVSLVAIKG 1071
+T + ++Y N SVS+ SE T ++ +K
Sbjct: 19235 LKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSE--------PSESTGPII-VKD 19285
Query: 1072 NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGF-KLGVRPSQGGEAPRE 1130
+ E P+ V ++ I EV + I P P I + K G+ +
Sbjct: 19286 DVEPPR---VMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEII 19342
Query: 1131 VTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGV 1190
T + + V Y + + R + KV+ PP LE N T
Sbjct: 19343 STDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAG-PLEINGLTAE 19401
Query: 1191 -LTVSWERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY--- 1243
++SW R DI Y + T+ E + +SC L G EY
Sbjct: 19402 KCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQ--MTSCKVTKLLKGNEYIFR 19459
Query: 1244 --NVSVYTVKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTN 1297
V+ Y V + ESV I VP PPT L T++ ++M + W+ P S +++
Sbjct: 19460 VTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISG 19519
Query: 1298 FLVRYSPVKNEEDVAELSISP-SDNAVVLTNLLPGTEYVVSV-----SSVYEQHESTPL- 1350
+++ KN ++ P D V T L G EY V + + E++PL
Sbjct: 19520 YIIERRE-KNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLI 19578
Query: 1351 RGRQKTGLDS-PTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDR 1405
R L S P+ D + T+ W+ P A ITGY + + + +
Sbjct: 19579 RAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEY--KKSDDTDWKTS 19636
Query: 1406 VPHSRNS-ITLTNLTPGTEYVVSIVALN-----------------GREESPLLIGQQSTV 1447
+ R + T++ LT G EYV + ++N REE PL
Sbjct: 19637 IQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLF----DID 19692
Query: 1448 SDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT-VPGSKSTATI- 1505
S++ + L V A ++ + + V + + + + + + S+++ TI
Sbjct: 19693 SEMRKTLIVKAGASFTMTVPFRGRPVP----NVLWSKPDTDLRTRAYVDTTDSRTSLTIE 19748
Query: 1506 -SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW-L 1563
+ YT+T+ V A+S + + P+ + V DV S + W +
Sbjct: 19749 NANRNDSGKYTLTIQNVLS-----AASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDV 19803
Query: 1564 PSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
P + +PV Y + + T ++ + LQ Y V +N G
Sbjct: 19804 PENDGGAPVKNYHIEKREASKKAWVSV-TNNCNRLSYKVTNLQEGAIYYFRVSGENEFGV 19862
Query: 1621 SQPLVQTAVTNIDR----PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTY--SSPEDGIH 1674
P I P+ L T + DS+ + W P+ V Y + E G
Sbjct: 19863 GIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQK 19922
Query: 1675 ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVT 1734
+ + GLR SEY V A E+Q + P +L +
Sbjct: 19923 NWVKCAVAKSTHHVVSGLRENSEYFFRVFA-----ENQ-------AGLSDPREL----LL 19966
Query: 1735 PTSLSAQWTPPNVQL-----------TGYRVRVTPKEKTGPMKEINLAPD---------- 1773
P + Q PP + + G ++V P+ ++ L+ D
Sbjct: 19967 PVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRF 20026
Query: 1774 SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV------VTTLENVSPPR-RARVTDAT 1826
++ + L + K V+ A + +T+ + G + L+ PP ++D T
Sbjct: 20027 NTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDIT 20086
Query: 1827 ETTITISWR---------------TKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTIT 1871
E ++T+ W K ET T AV + RT+ +
Sbjct: 20087 EESVTLKWEPPKYDGGSQVTNYILLKRETST-----AVWTEVSATVARTM------MKVM 20135
Query: 1872 GLQPGTDYKIYL-----YTLNDNARSSPVVIDASTAIDAPSNLRFLA-TTPNSLLVSWQP 1925
L G +Y+ + + ++D+ S+ V + P + ++ T S+ V W
Sbjct: 20136 KLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHE 20195
Query: 1926 P----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL----- 1976
P + + GY ++ + S + + T +T + G Y V A
Sbjct: 20196 PVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGV 20255
Query: 1977 -KNNQKSEPLI 1986
K + SEP++
Sbjct: 20256 GKPSHPSEPVL 20266
Score = 106 bits (264), Expect = 3e-22
Identities = 279/1348 (20%), Positives = 495/1348 (36%), Gaps = 168/1348 (12%)
Query: 773 TSVNIPDLLPGRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSI 827
TS + LL G +YI VN Y + E E I + T P P + V S+
Sbjct: 19443 TSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESM 19502
Query: 828 VVRWSRPQAP----ITGYRIVYSPSVEGSSTELNL-PETANSVTLSDLQPGVQYNITIYA 882
+ WSRP++ I+GY I +N P V + L+ G +Y +YA
Sbjct: 19503 TLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYA 19562
Query: 883 VEENQESTPVVIQQETTGTPRSDT---VPSPRDL-QFVEVTDVKVTIMWTPP----ESAV 934
+ + + + ET+ R++ +PSP + V+ +TI W P + +
Sbjct: 19563 ----ENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPI 19618
Query: 935 TGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA--- 991
TGY V+ + + + R T ++GL+ G Y F+V +V+ S P +
Sbjct: 19619 TGYTVEYKKSD-DTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDP 19677
Query: 992 QQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP------------ 1039
Q + + +E T++V+ G T+ + RG+P
Sbjct: 19678 QIAKEREEEPLFDIDSEMRKTLIVK--------AGASFTMTVPFRGRPVPNVLWSKPDTD 19729
Query: 1040 ---RQYNVGPSVSKYPLR----NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIP 1092
R Y V + S+ L N + +YT+++ + V T P ++I
Sbjct: 19730 LRTRAY-VDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNIT 19788
Query: 1093 PYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDSG--SIVVSGLT 1144
+VT+ + V++W AP + + R + +A VT++ S V+ L
Sbjct: 19789 VQ--DVTKESAVLSWDVPENDGGAPVKNYHIEKREASK-KAWVSVTNNCNRLSYKVTNLQ 19845
Query: 1145 PGVEYVYTIQVLRD---GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW---ERS 1198
G Y + + + G + K+ SPP L + + V +++W E
Sbjct: 19846 EGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSV-SLTWLKPEHD 19904
Query: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
I Y + Q N ++ V A + L EY V+ S P
Sbjct: 19905 GGSRIVHYVVEALEKG--QKNWVKCAV-AKSTHHVVSGLRENSEYFFRVFAENQAGLSDP 19961
Query: 1259 ISDTIIPAV------PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVA 1312
+ ++P + PP D++ N T+ V +D+ V D
Sbjct: 19962 -RELLLPVLIKEQLEPPEIDMK--NFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGV 20018
Query: 1313 ELSISPSDNA-VVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD--------SPTG 1363
L + N + NL + V+ + + + G K ++ PTG
Sbjct: 20019 PLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTG 20078
Query: 1364 -IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNL 1418
+ SDIT S T+ W P+ + +T Y + E + E +R + + L
Sbjct: 20079 PVVISDITEESVTLKWEPPKYDGGSQVTNYILLKR-ETSTAVWTEVSATVARTMMKVMKL 20137
Query: 1419 TPGTEYVVSIVALNGR------EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA 1472
T G EY I A N + + + + T P V T S+ + W P
Sbjct: 20138 TTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPV 20197
Query: 1473 VT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSP 1528
V Y + + + + + ++ + G+ Y VYA G
Sbjct: 20198 SNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGK 20257
Query: 1529 ASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGP 1584
S + + P +++TD+ NS+S+ W S +TGY V
Sbjct: 20258 PSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRW 20317
Query: 1585 TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-SQPL-VQTAVTNIDRPKGLAFTD 1642
TK +T+ I GL +Y V+A+N G S P V +T ID G D
Sbjct: 20318 TKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVI-D 20376
Query: 1643 VDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSV 1702
+ ++ ++ + G + R S E + D E T L + ++ +
Sbjct: 20377 LPLEYTEVV-KYRAGTSVKLRAGISGKPAPTIEWYK-DDKELQTNALVCVENTTDLASIL 20434
Query: 1703 VALHDDMES-------QPLIGTQSTAI---------PAPTDLKFTQVTPTSLSAQWTPP- 1745
+ D + S + +G+ S I P ++F VT ++ W PP
Sbjct: 20435 IKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPA 20494
Query: 1746 ---NVQLTGYRVRVTPKEKTGPM--KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT 1800
++T Y + K +T + ++ + + + ++ +Y V A+
Sbjct: 20495 DDGGAKITHY---IVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGI 20551
Query: 1801 SRPAQGVVTTLENV----SPPRRARVTDATETTITISWRTKT----ETITGFQV---DAV 1849
P + +N PP VT T+ ++T+ W I+G+ + D
Sbjct: 20552 GEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKK 20611
Query: 1850 PANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNAR---SSPVVI-DASTAIDA 1905
++ TI+ D R +TGL +DY+ + +N + S P A+ ID
Sbjct: 20612 SLGWFKVLKETIR-DTRQ-KVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDP 20669
Query: 1906 P---SNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVP-RPRPGVTE 1957
P + +R +T +S+ + W P + +TGY+++ + V + TE
Sbjct: 20670 PGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTE 20729
Query: 1958 ATITGLEPGTEYTIYVIALKNNQKSEPL 1985
++ L+PG Y V A+ + EP+
Sbjct: 20730 YVVSNLKPGVNYYFRVSAVNCAGQGEPI 20757
Score = 103 bits (256), Expect = 3e-21
Identities = 283/1422 (19%), Positives = 486/1422 (34%), Gaps = 190/1422 (13%)
Query: 730 EITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRK 785
+IT S ++W D ++G+ VE + +D T +PDL+ G++
Sbjct: 7001 DITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFV-TDLEFTVPDLVQGKE 7059
Query: 786 YIVNVYQISE--DGEQSLILSTSQTTAPDAPPDP--TVDQVDDT--SIVVRWSRPQ---- 835
Y+ V ++ GE + + + P PDP V D T SI + W P+
Sbjct: 7060 YLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGG 7119
Query: 836 APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ 895
+ I GY + P P + ++ L+ G Y + A+ S P
Sbjct: 7120 SRIKGYIVERCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPT 7179
Query: 896 QETTGTPRSDTVPSPRDLQFVEVTDVKV-------TIMWTPPESAVTGYRVDVIPVNLPG 948
+E + D++ + VK + PE +T + D+I
Sbjct: 7180 EEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKR 7239
Query: 949 EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE 1008
+ +P + S TY + V GR + + K P +
Sbjct: 7240 ITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVC-GRATAVVEVNVLDKPGPPAAFDITDV 7298
Query: 1009 TDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTV 1064
T+ + L+ W PPR ++IT Y + T + + + + L P EY
Sbjct: 7299 TNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIF 7358
Query: 1065 SLVA--IKGNQESPKATGVFTTLQPGSSIPPYNTE---VTETTIVITWTP------APRI 1113
+ A + G E +A+ + Q PP E +T+ + +TW +P
Sbjct: 7359 RVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPIT 7418
Query: 1114 GF---KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTI---QVLRDGQERDAPIV 1167
G+ +L + + D+ + V GLT +Y + + + G+ +
Sbjct: 7419 GYWVERLDPDTDKWVRCNKMPVKDT-TYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEP 7477
Query: 1168 NKVVTPLSPPTNLHLEANPDTGVLTV--SWERSTTPDITGYRITTTPTNGQQGNSLEEVV 1225
+ P+ PP D G +V +W T P+ G + +E V
Sbjct: 7478 ILIKDPIDPPWPPGKPTVKDVGKTSVRLNW---TKPEHDGGAKIESYVIEMLKTGTDEWV 7534
Query: 1226 HADQSSCTFDNLSPGL----EYNVSVYTVKDDKESVPI--SDTIIPAVP-----PPTDLR 1274
+ T +L PGL EY+ V V ES P SD ++ PP L
Sbjct: 7535 RVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLE 7594
Query: 1275 FTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
NI +T + W P +TN++V V+ + + + D +T L G
Sbjct: 7595 VINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRK-GWQTVDTTVKDTKCTVTPLTEG 7653
Query: 1332 TEYVVSVS-------SVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR-- 1382
+ YV V+ S Y + E + L T P + D+T + W P+
Sbjct: 7654 SLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKND 7713
Query: 1383 --ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREE 1436
I Y I + + + + +T++ GTE + A N G
Sbjct: 7714 GGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPS 7773
Query: 1437 SP---LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQE 1493
P L I ++ P DL V A + I+W P E G SP+
Sbjct: 7774 EPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPP------------EKNGGSPIIG 7821
Query: 1494 FTVP----GSKSTATIS-------------GLKPGVDYTITVYAVTGRGDSPASSKPISI 1536
+ V G++ ++ G+ P +Y + V AV G S+P I
Sbjct: 7822 YHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIG----VSEPSEI 7877
Query: 1537 NYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1596
+ P D++ + I V S +R P + D+
Sbjct: 7878 SENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLT 7937
Query: 1597 MTIEGLQPTVEYVVSVYA---------QNPSGESQPLVQTAVTNIDRP-KGLAFTDVDVD 1646
M + + +E SV A +N G + + V + P K + +D+
Sbjct: 7938 MKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKS 7997
Query: 1647 SIKIAWESPQ--GQVSRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVSVV 1703
S K+ WE P+ G E G P GE + ++ L P EY V
Sbjct: 7998 SCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVK 8057
Query: 1704 ALH-----DDME-SQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPP----NVQLTGY 1752
A++ + +E P+I P P D++ T +++ W PP ++ GY
Sbjct: 8058 AVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGY 8117
Query: 1753 RV-RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTL 1811
+ ++ E+ +L P + GL +Y+ V A S P++ T
Sbjct: 8118 IIEKIAKGEERWKRCNEHLVP-ILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPT- 8175
Query: 1812 ENVSPPRRARVTDATETTI------------------TISWRTKTETITGFQVD------ 1847
+ V P +V T + TI+W I ++
Sbjct: 8176 KAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPL 8235
Query: 1848 --------------AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL-NDNA-R 1891
+P + I + K + + L+P D+ +Y+ + ND+
Sbjct: 8236 VRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRP--DHGLYMIKVENDHGIA 8293
Query: 1892 SSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPRE- 1946
+P + P N F S+L W+PP + I Y ++ + P E
Sbjct: 8294 KAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEW 8353
Query: 1947 VVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGR 1988
+V + ++T L G EY V A P + +
Sbjct: 8354 IVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSK 8395
Score = 101 bits (252), Expect = 8e-21
Identities = 253/1300 (19%), Positives = 457/1300 (35%), Gaps = 239/1300 (18%)
Query: 718 FSPLVATSESVTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTA- 772
F P T+ + + T +S ++W + G+ VE + + +E + P T
Sbjct: 17421 FKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVE--ICKADEEEWQIVTPQTGL 17478
Query: 773 --TSVNIPDLLPGRKYIVNVYQISEDG--EQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828
T I L ++Y + V +++ G E + + T + P+ +D IV
Sbjct: 17479 RVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIV 17538
Query: 829 VRW---SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYN-ITIYAVE 884
VR +R P G +P + S E + ++ GV Y ++I +
Sbjct: 17539 VRAGGSARIHIPFKGRP---TPEITWSREEGEFTDKVQ------IEKGVNYTQLSIDNCD 17589
Query: 885 ENQESTPVVIQQETTGTPRS-------DTVPSPRDLQFVEVTDVKVTIMWTPP----ESA 933
N ++ + ++G+ + DT P++L EV ++W PP +
Sbjct: 17590 RNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAK 17649
Query: 934 VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ 993
V Y +D S+ +F +V L+ G YYF+V A + P+
Sbjct: 17650 VKNYVIDKRESTRKAYANVSSKCSKTSF-KVENLTEGAIYYFRVMAENEFGVGVPVETVD 17708
Query: 994 TTKLDAP------TNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYN 1043
K P L V++T ++++ W P +++ GY V + +G +
Sbjct: 17709 AVKAAEPPSPPGKVTLTDVSQTSASLM--WEKPEHDGGSRVLGY--VVEMQPKGTEKWSI 17764
Query: 1044 VGPS-VSKYPLRNLQPASEYTVSLVAIKGNQES-PKATGV-----FTTLQPGSSIPPYNT 1096
V S V + L EY + A +S P+ GV T+QP + P+NT
Sbjct: 17765 VAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKL-PFNT 17823
Query: 1097 EVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVL 1156
+ G + E+ V+ P + +V
Sbjct: 17824 YSIQA----------------------GEDLKIEIP------VIGRPRPNISWV------ 17849
Query: 1157 RDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQ 1216
+DG+ PL T +++E + VL + + D Y +T T + G
Sbjct: 17850 KDGE------------PLKQTTRVNVEETATSTVLHI--KEGNKDDFGKYTVTATNSAGT 17895
Query: 1217 QGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFT 1276
+L +V PG PP +RF
Sbjct: 17896 ATENLSVIVLE----------KPG---------------------------PPVGPVRFD 17918
Query: 1277 NIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLP 1330
+ D + ++W PP ++N++V K + +S + + + +T L
Sbjct: 17919 EVSADFVVISWEPPAYTGGCQISNYIVE----KRDTTTTTWHMVSATVARTTIKITKLKT 17974
Query: 1331 GTEYVVSVSSVYEQHESTPLRGR-----QKTGLDSPTGIDF-SDITANSFTVHWIAP--- 1381
GTEY + + +S PL + P G F + I+ + V W P
Sbjct: 17975 GTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVND 18034
Query: 1382 -RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440
I GY + ++ + ++ P T L G EY + A E+ +
Sbjct: 18035 GGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSA-----ENIVG 18089
Query: 1441 IGQQSTVS---------DVPRDLEVVAATPTSLLISWDAPAV----TVRYYRITYGETGG 1487
IG+ S VS D P E + T ++ + W PA + Y + +
Sbjct: 18090 IGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPD 18149
Query: 1488 NSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPS 1546
++ ++ T+SGL Y V A G+ S S +I R EID P+
Sbjct: 18150 GRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPN 18209
Query: 1547 QMQVTDVQDNSI--SVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
+D + + + + + G + + G +TA + + TI+
Sbjct: 18210 ASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTL 18269
Query: 1605 TV---------EYVVSVYAQNPSG-ESQPLVQTAVTNIDRPKG-LAFTDVDVDSIKIAWE 1653
V +Y++ + N G +S P+ + P+G L T V + +AW
Sbjct: 18270 VVKDCIRTDGGQYILKL--SNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWN 18327
Query: 1654 SP----QGQVSRY--------RVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVS 1701
P +S Y R++++ + L ++ L PG+EY
Sbjct: 18328 PPLQDGGANISHYIIEKRETSRLSWTQVSTEVQAL---------NYKVTKLLPGNEYIFR 18378
Query: 1702 VVALH-----DDMESQPLIGTQSTAIPAPTDL-KFTQVTPTSLSAQWTPP----NVQLTG 1751
V+A++ + +ES P+ P P + + +T S+ W P ++ G
Sbjct: 18379 VMAVNKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEG 18438
Query: 1752 YRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVV--- 1808
Y + KE K + V+GL YE V A P++ V
Sbjct: 18439 YILEKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYR 18498
Query: 1809 --TTLENVSPPRRARVTDATETTITISWRTKT----ETITGF--QVDAVPANGQTPIQRT 1860
L PP +VTD + ++++++W + G+ +V A+ T
Sbjct: 18499 ACDALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPP 18558
Query: 1861 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAS 1900
+ +T+T L+ T+Y + +N P + S
Sbjct: 18559 TGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGS 18598
Score = 101 bits (252), Expect = 8e-21
Identities = 308/1501 (20%), Positives = 533/1501 (35%), Gaps = 204/1501 (13%)
Query: 624 NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNS--YTIKGLKPGVVYE 678
NS + W P+ S I +YIL R K S RW + ++ + + GL G YE
Sbjct: 21669 NSITLTWARPESDGGSEIQQYILERREKKST-RWVKVISKRPISETRFKVTGLTEGNEYE 21727
Query: 679 GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
+++ G + PV P P V VT+ + ++ +
Sbjct: 21728 FHVMAENAAGVGPASGIS-RLIKCREPVNP--------PGPPTVV---KVTDTSKTTVSL 21775
Query: 739 SW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQIS 794
W + G+ +E ++ GD + T + DL G +Y V I+
Sbjct: 21776 EWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAIN 21835
Query: 795 EDGEQSLILSTSQTTAPD--APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGS 852
G+ T A D P+ +D + VVR Y+ +P+ S
Sbjct: 21836 GAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWS 21895
Query: 853 STELNLPETANSVTLSDLQPGVQYNIT-------IYAVEENQESTPVVIQQETTGTPRSD 905
+ NL A+ T N VE N S + + TP
Sbjct: 21896 KPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP- 21954
Query: 906 TVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
P + F +VT T+MW P + + Y V+ + +R F
Sbjct: 21955 ----PGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIF 22010
Query: 962 AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ----TTKLDAPTNLQFVNETDSTVLVRW 1017
+V L+ GV YYF+V AV+ +P + T + P L V+ + S+ ++ W
Sbjct: 22011 -KVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAW 22069
Query: 1018 TPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEY---------- 1062
P ++ITGY L + ++G G + + + L +EY
Sbjct: 22070 LKPDHDGGSRITGYLLE--MRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDA 22127
Query: 1063 -------TVSLVAIKGNQESPKA--TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI 1113
S V IK Q P A TG+ L + P+ +V I+ PAP++
Sbjct: 22128 GYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVP-----ISGRPAPKV 22182
Query: 1114 GFKL-GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT 1172
+KL +R + T D ++ V G Y + + + + V+
Sbjct: 22183 TWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIG 22242
Query: 1173 PLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQ 1229
P T ++ +SW + +IT Y + + + V Q
Sbjct: 22243 RPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQ 22302
Query: 1230 SSCTFDNLSPGLEYNVSV-----YTVKDDKESVPISDTIIPAVPP--PTDLRFTNIGPDT 1282
T +L+ +EY+ V + V ES PI P VPP PT ++ +
Sbjct: 22303 IKVT--HLTKYMEYSFRVSSENRFGVSKPLESAPII-AEHPFVPPSAPTRPEVYHVSANA 22359
Query: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEED----VAELSISPSDNAVVLTNLLPGTE----- 1333
M + W P D + ++ Y K E + V E + + +T L+ G E
Sbjct: 22360 MSIRWEEPYH-DGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRT 22418
Query: 1334 YVVSVSSVYEQHE-STPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGY 1388
Y ++ + V + E S P+ + +D+P + +D+T ++ ++ W AP + + GY
Sbjct: 22419 YALNAAGVSKASEASRPIMAQNP--VDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGY 22476
Query: 1389 RIRHHPEHFSGRPREDRVPH---SRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS 1445
I P G R + + S N T+T L+ G Y ++A N + G +S
Sbjct: 22477 IIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNA--AGVISKGSES 22534
Query: 1446 TVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI 1505
T RD + D + + GG + G K
Sbjct: 22535 TGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLC 22594
Query: 1506 SGLKPGVDYT----ITVYAVTGRGDS---------PASSKPISINYRTEIDKP---SQMQ 1549
K + YT V R DS + +K +S+ + +D P ++
Sbjct: 22595 E--KVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV-LDSPGPCGKLT 22651
Query: 1550 VTDVQDNSISVKW-LP---SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPT 1605
V+ V ++ W LP + +T Y V + +T+ + + +EG PT
Sbjct: 22652 VSRVTQEKCTLAWSLPQEDGGAEITHYIV----------ERRETSRLNW--VIVEGECPT 22699
Query: 1606 VEYVVS-----------VYAQNPSG-----ESQPLVQTAVTNIDRPKGL-AFTDVDVDSI 1648
+ YVV+ V A N G ES+P+V I P G+ + I
Sbjct: 22700 LSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHI 22759
Query: 1649 KIAWESPQ----GQVSRYRVTYSSPED----GIHELFPAPDGEEDTAELQGLRPGSEYTV 1700
I W P+ ++S Y V + +++ + D ++ L G +Y
Sbjct: 22760 IIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYD---TRLKVTSLMEGCDYQF 22816
Query: 1701 SVVALHDDMESQP------LIGTQSTAIPAPTDL-KFTQVTPTSLSAQWTPP----NVQL 1749
V A++ S+P + + + P P + T S+S WT P +
Sbjct: 22817 RVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDI 22876
Query: 1750 TGYRVRVTPKEKTGPMK-EINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV- 1807
GY + + K+ + N ++ V L + KY V A+ S ++ +
Sbjct: 22877 VGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIA 22936
Query: 1808 -VTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPA-----NGQTPIQRTI 1861
+ +E + P + D + T+TI + P G R I
Sbjct: 22937 EIEPVERIEIP-DLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAI 22995
Query: 1862 KPDVRSYTITGLQPGTDYKIYLYTL---NDNARSSPVVIDASTAIDAP-SNLRFLATTPN 1917
SY++ + Y YT+ N + + S V+ P +++ + +
Sbjct: 22996 IDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRD 23055
Query: 1918 SLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYV 1973
S+ ++W+ P A + YI++ + + V + T I+GL GT Y V
Sbjct: 23056 SVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTV-TTKCSKTLYRISGLVEGTMYYFRV 23114
Query: 1974 I 1974
+
Sbjct: 23115 L 23115
Score = 98.2 bits (243), Expect = 8e-20
Identities = 288/1429 (20%), Positives = 523/1429 (36%), Gaps = 305/1429 (21%)
Query: 624 NSHPIQWNAPQPSHISKYILRW---RPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQ 680
N+ I+W P SK I W + +N++ KE +P +Y + GL G+ Y+ +
Sbjct: 22358 NAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFR 22417
Query: 681 LISIQQYGHQEVTRFDFTTTSTSTPVTS-NTVTGETTPFSPLVATSESVTEITASSFVVS 739
++ G + + S P+ + N V P VT++T S+ +
Sbjct: 22418 TYALNAAGVSKASE-------ASRPIMAQNPVDAPGRP---------EVTDVTRSTVSLI 22461
Query: 740 WVSAS----DTVSGFRVEYELSEEGDEPQYLDLPSTATSVN---IPDLLPGRKYIVNVYQ 792
W + + V G+ +E + E + ++L T S N + L G Y V
Sbjct: 22462 WSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLA 22521
Query: 793 ISEDGEQSLILSTSQTTAPD------APPDPTVD-QVDDTSIVVRWSRPQAPITGYRIVY 845
+ G +I S++T P APP +D ++ + +R G +V
Sbjct: 22522 KNAAG---VISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIR--------AGSDLVL 22570
Query: 846 SPSVEGS----------STELNLPETANS----------VTLSDLQPGVQYNITIYAVEE 885
+V G EL+L E + + D +Y +T+
Sbjct: 22571 DAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASG 22630
Query: 886 NQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDV 941
+ + +V ++ G TV VT K T+ W+ P+ + +T Y V+
Sbjct: 22631 TKAVSVMVKVLDSPGPCGKLTVS--------RVTQEKCTLAWSLPQEDGGAEITHYIVE- 22681
Query: 942 IPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYY-----------FKVFAVS-HGR----E 985
R SR + V G P ++Y F+V AV+ +G E
Sbjct: 22682 -----------RRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVE 22730
Query: 986 SKPLTAQQTTKLDAPTNL-QFVNETDSTVLVRWTPPRA----QITGYRLTVGLTRRGQPR 1040
S+P+ A+ + + +P + + V ++++WT P + +I+ Y V + R
Sbjct: 22731 SEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNY--LVDKREKKSLR 22788
Query: 1041 QYNVGPSVSKYPLR----NLQPASEYTVSLVAIK--GNQESPKATGVFTTLQPGSSIPPY 1094
V Y R +L +Y + A+ GN E +A+ + +P
Sbjct: 22789 WTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREP------- 22841
Query: 1095 NTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTP----GVEYV 1150
++TP P PS APR V + SI ++ P G + V
Sbjct: 22842 -----------SYTPGP---------PS----APRVVDTTKHSISLAWTKPMYDGGTDIV 22877
Query: 1151 -YTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDIT----- 1204
Y +++ QE+D +V H A T+ T PD+
Sbjct: 22878 GYVLEM----QEKDTDQWYRV----------HTNA-------TIRNTEFTVPDLKMGQKY 22916
Query: 1205 GYRITTTPTNG--QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDT 1262
+R+ G + S+ E+ ++ L+ L+ V++ + V +S
Sbjct: 22917 SFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGR 22976
Query: 1263 IIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNA 1322
PPP +TW+ IDL + + + E + L +
Sbjct: 22977 -----PPPV-------------ITWSKQ-GIDLASRAI----IDTTESYSLLIVDK---- 23009
Query: 1323 VVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR 1382
N +Y + + + +T L T P+ + +++ +S T+ W P
Sbjct: 23010 ---VNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPS-VKVKEVSRDSVTITWEIPT 23065
Query: 1383 ----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITL---TNLTPGTEYVVSIVALNGRE 1435
A + Y + E R + ++ S TL + L GT Y ++
Sbjct: 23066 IDGGAPVNNYIV----EKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLP----- 23116
Query: 1436 ESPLLIGQQSTVSD---------VPRDLEVVAATPTSLLISWDAPAVT----VRYYRITY 1482
E+ IG+ SD VP LEVV T +++ ++W+ P + Y +
Sbjct: 23117 ENIYGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEA 23176
Query: 1483 GETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEI 1542
+ G ++ T+ + T++ L G Y + A +G S ++ +
Sbjct: 23177 CKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLR 23236
Query: 1543 DKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGP------------------ 1584
P+ + ++ + +I V P+ PV P G P
Sbjct: 23237 VLPT-IDLSTMPQKTIHV---PAGRPVE----LVIPIAGRPPPAASWFFAGSKLRESERV 23288
Query: 1585 ---TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKG--LA 1639
T TK A E TI + T EY + + +N +G + ++ + + P +
Sbjct: 23289 TVETHTKVAKLTIRETTI---RDTGEYTLEL--KNVTGTTSETIKVIILDKPGPPTGPIK 23343
Query: 1640 FTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEE---DTAELQGLRPGS 1696
++D SI I+WE P+ Y + H P E T + L G+
Sbjct: 23344 IDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGN 23403
Query: 1697 EYTVSVVALH-----DDMESQPLIGTQSTAIPAPTD-LKFTQVTPTSLSAQWTPPN---- 1746
EY V A + ++S+ + S IP P + L+ V+ ++ W PP
Sbjct: 23404 EYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGG 23463
Query: 1747 VQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVS-GLMVATKYEVSVYALK---DTLTSR 1802
Q+TGY V + + +N P + + S GL +YE V A+ SR
Sbjct: 23464 SQVTGYIVE-RKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSR 23522
Query: 1803 PAQGVVTTLENVSPP---RRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQT 1855
P++ +V ++ ++PP + RVTD T T+++++W + +TG+ ++ +
Sbjct: 23523 PSKPIVA-MDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHE 23581
Query: 1856 PIQ-RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI 1903
+ T +R YT+T L G +Y+ + N P + + +
Sbjct: 23582 WTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKV 23630
Score = 97.1 bits (240), Expect = 2e-19
Identities = 340/1573 (21%), Positives = 568/1573 (36%), Gaps = 223/1573 (14%)
Query: 619 TPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
T S +S +QWN P S + Y L + +NS+ K P + GL+ GV
Sbjct: 15853 TLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGV 15912
Query: 676 VYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASS 735
YE ++ + G P + P P E++ +T +S
Sbjct: 15913 EYEFRVSAENIVG-------------IGKPSKVSECYVARDPCDP-PGRPEAII-VTRNS 15957
Query: 736 FVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVY 791
+ W ++G+ VE + EG + T + L+ +Y V
Sbjct: 15958 VTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVI 16017
Query: 792 QISEDGEQSLIL-STSQTTAPDA--PPDPTVDQVDDTSIVVRWS---RPQAPITGYRIVY 845
+ G S ST TA D PP ++D +IVV + A I G I
Sbjct: 16018 ARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPI-- 16075
Query: 846 SPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
P+++ + L TA + +D + + +S +++ + RS
Sbjct: 16076 -PTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV-----DSGNYILKAKNVAGERS 16129
Query: 905 DTV-------PSPRDLQFV--EVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP 955
TV P P + V VT K T+ W PP + D+I + RL
Sbjct: 16130 VTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPP---LQDGGSDIINYIVERRETSRLV 16186
Query: 956 IS------RNTFAEVTGLSPGVTYYFKVFAVS-----HGRESKPLTAQQTTKL-DAPTNL 1003
+ + +VT L G Y F++ AV+ ES+P+ A+ + DAP
Sbjct: 16187 WTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAP 16246
Query: 1004 QFVNETDSTVLVRWTPPRA----QITGYRLTV----GLTRRGQPRQYNVGPSVSKYPLRN 1055
+ T +++V W P + +I GY L G+ R + + +G +
Sbjct: 16247 EVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGI-RWTRCHKRLIGELRLRVTGLI 16305
Query: 1056 LQPASEYTVSLVAIKGNQE-SPKAT---GVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
E+ VS G E SP + +PG P ++T +++ ++W+
Sbjct: 16306 ENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPI 16365
Query: 1112 RIGF---------KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD---G 1159
G K V + + +I V L EY + I + G
Sbjct: 16366 YDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVG 16425
Query: 1160 QERDAPIVNKVVTPL-SPPTNLHLEANPDTGV-------LTVSWERSTTPDITGYRITTT 1211
+ D P V L +P +L LE + L V + TP++ ++
Sbjct: 16426 EHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKV--- 16482
Query: 1212 PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV----KDDKESVPISDTIIPAV 1267
+G+ ++ V + +S DN++ Y+ YT+ +S ++ ++
Sbjct: 16483 --DGEIRDAAIIDVTSSFTSLVLDNVN---RYDSGKYTLTLENSSGTKSAFVTVRVLDTP 16537
Query: 1268 PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAELSISPSDNAVV 1324
PP +L+ T I D++ +TW PP +D + + Y K E + A + + N+
Sbjct: 16538 SPPVNLKVTEITKDSVSITW-EPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWK 16596
Query: 1325 LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL----DSPTGIDFSDITANSFTVHWIA 1380
+ L G Y V++ E P + + P I D+T NS ++ W
Sbjct: 16597 IDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTK 16656
Query: 1381 PR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436
P + I Y + +H RV + +TNLT G EY+ +VA+N +
Sbjct: 16657 PEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQ--AVITNLTQGEEYLFRVVAVNEKGR 16714
Query: 1437 S-PLLIGQQSTVSDVPRDLEVVAA-TPTSLLISWD----APAVTVRYYRITYGETGGNSP 1490
S P + D+ + +V A + S+ + D P IT+ + G P
Sbjct: 16715 SDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDG--LP 16772
Query: 1491 VQEFT---VPGSKSTATIS----GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
+++ T V S T+S G Y ITV V G+ K SI T +D
Sbjct: 16773 LKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQ-------KTASIEIVT-LD 16824
Query: 1544 KP----SQMQVTDVQDNSISVKWLP----SSSPVTGYRV-----TTTPKNGPGPTKTKTA 1590
KP ++ DV SI++ W P +T Y V TTT + T +T
Sbjct: 16825 KPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTT 16884
Query: 1591 GPDQTEMTIEGLQPTVEYVVSVYAQNPSG-----ESQPLVQTAVTNIDRPKGLAF-TDVD 1644
+ + L+ EY ++A+N G ES P+V P G F T +
Sbjct: 16885 ------LKVTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAIS 16938
Query: 1645 VDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE---EDTA-ELQGLRPGSEYTV 1700
DS+ I W P + Y + + + DT + Q L G EY
Sbjct: 16939 KDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEF 16998
Query: 1701 SVVALHDDMESQPLIGTQSTAIPAPTDLKFT----QVTPTSLSAQWTPP----NVQLTGY 1752
V A + + ++ P D T V ++ QWT P +TGY
Sbjct: 16999 RVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGY 17058
Query: 1753 RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT-LTSRPAQ--GVVT 1809
V MK + VSGL +YE V A S+P+ G +T
Sbjct: 17059 IVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPIT 17118
Query: 1810 TLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYT 1869
+ V PR + +T + + T F+++A P ++ D
Sbjct: 17119 AKDEVELPRISMDPKFRDTIVVNAGET-------FRLEADVHGKPLPTIEWLRGDKEIEE 17171
Query: 1870 ITGLQ-PGTDYKIYL------------YTLNDN----ARSSPV---VIDASTAIDAPSNL 1909
+ TD+K L Y L + ++S PV V+D + P +
Sbjct: 17172 SARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGP--V 17229
Query: 1910 RFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEP 1965
+ T ++W PP + I+ Y+++ ++ S V +T L
Sbjct: 17230 QVTGVTSEKCSLTWSPPLQDGGSDISHYVVE-KRETSRLAWTVVASEVVTNSLKVTKLLE 17288
Query: 1966 GTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTH 2025
G EY ++A+ EPL + P L+ P P+ L+V + + + V
Sbjct: 17289 GNEYVFRIMAVNKYGVGEPL------ESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCW 17342
Query: 2026 PGYDTGNGIQLPG 2038
D+ G ++ G
Sbjct: 17343 NRPDSDGGSEIIG 17355
Score = 94.0 bits (232), Expect = 2e-18
Identities = 154/662 (23%), Positives = 253/662 (38%), Gaps = 93/662 (14%)
Query: 1447 VSDVP---RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
V DVP R+LEV + ++W+ P I Y + + + + ++ +
Sbjct: 6589 VIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAES 6648
Query: 1504 ---TISGL-KPGVDYTITVYAVT--GRGDSPASSKPISINYRTEIDKPS-QMQVTDVQDN 1556
T++GL K GV+Y V A G G+ + P+ + ++ P + +TDV
Sbjct: 6649 CEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRF 6708
Query: 1557 SISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV 1612
+S+ W P + +T Y + K T + T+ + EY V
Sbjct: 6709 GVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRV 6768
Query: 1613 YAQNPSGESQPLVQTAVTN----IDRPK---GLAFTDVDVDSIKIAWESPQGQVSRYRVT 1665
AQN G +P T I+RP L +D S+++ WE P +
Sbjct: 6769 RAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILG 6828
Query: 1666 Y--SSPEDGIH-------ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIG 1716
Y E+G +L P E T ++ GL G++Y V A + S P
Sbjct: 6829 YIIERCEEGKDNWIRCNMKLVP-----ELTYKVTGLEKGNKYLYRVSAENKAGVSDP--- 6880
Query: 1717 TQSTAIPAPTDLKFTQVTPT-SLSA-----QWTPPN-----VQLTGY-RVRVT-----PK 1759
+ I P V PT LSA + PN V TGY R T
Sbjct: 6881 ---SEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKV 6937
Query: 1760 EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPP 1817
+TG ++ + +V+S + + + +Y LK + G V + S P
Sbjct: 6938 LETGDRVKMKTLSAYAELVISP---SERSDKGIYTLKLENRVKTISGEIDVNVIARPSAP 6994
Query: 1818 RRARVTDATETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGL 1873
+ + D T+ ++ ++W + +TG+ V+ + +T + +T+ L
Sbjct: 6995 KELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDL 7054
Query: 1874 QPGTDYKIYLYTLNDNARSSPVVIDA-------STAIDAPSNLRFLATTPNSLLVSWQPP 1926
G +Y + N P +D +T D P N+++ T NS+ ++W PP
Sbjct: 7055 VQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPP 7114
Query: 1927 R----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 1982
+ +RI GYI++ GS P T+ +TGLE G Y V AL S
Sbjct: 7115 KNDGGSRIKGYIVERCPRGSDKWVACGEP-VAETKMEVTGLEEGKWYAYRVKALNRQGAS 7173
Query: 1983 EPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQ 2042
+P + T+E+ + T P + LDV T G I+LP T
Sbjct: 7174 KP---SRPTEEIQAVDTQEAPEI----FLDVKLLAGLT-------VKAGTKIELPATVTG 7219
Query: 2043 QP 2044
+P
Sbjct: 7220 KP 7221
Score = 94.0 bits (232), Expect = 2e-18
Identities = 327/1598 (20%), Positives = 576/1598 (36%), Gaps = 255/1598 (15%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W+ P+ S I+ +I+ R + W++ I + I GL G Y+ ++I+
Sbjct: 8718 LNWSDPEDDGGSEITGFIIE-RKDAKMHTWRQP-IETERSKCDITGLLEGQEYKFRVIAK 8775
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV--- 741
++G PV + P + TE T S+ + W
Sbjct: 8776 NKFG-------------CGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPR 8822
Query: 742 -SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQS 800
+ + G+ +E ++ D + TS + +L + Y V ++E GE
Sbjct: 8823 SNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESE 8882
Query: 801 LILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWSRP---QAPITGYRIVYSPSVEGSST 854
L + D P PT+ V +I V+ P A +TG + P +E S
Sbjct: 8883 PSLPLNVVIQDDEVP-PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPM---PKIEWSKN 8938
Query: 855 E--LNLPETANSVTLSDLQPG-VQYNITI-YAVEENQESTPVVIQQETTGTPRS------ 904
E + P A +T ++ + ++I AV E++ + V R+
Sbjct: 8939 ETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVY 8998
Query: 905 DTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
D PR+L ++ + W P S +T Y +D + + + NT
Sbjct: 8999 DRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVT---NT 9055
Query: 961 FAE----VTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKLDAPTNL-QFVNETD 1010
E + L P Y F+V + +S +S + Q +L P + + T
Sbjct: 9056 AVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTK 9115
Query: 1011 STVLVRWTPP----RAQITGYRLTVGLTRRGQPRQY----------NVGPSVSKYPLRNL 1056
++LV WTPP + ITGY L +R + Y VG ++ + L
Sbjct: 9116 GSMLVSWTPPLDNGGSPITGY----WLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRL 9171
Query: 1057 QPASEYTVSLVAIKG------NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
+Y +AI ++ S PG P + T+++I + W P
Sbjct: 9172 LEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPP 9231
Query: 1111 PRIGFKLGVRPSQG--GEAPREVTSD------------SGSIVVSGLTPGVEYVYTIQVL 1156
K G P +G E E T+D + VV L +Y + ++ +
Sbjct: 9232 A----KDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAV 9287
Query: 1157 RD-GQERDAPIVNKV-VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT- 1213
+ G+ + ++ T + + ++ ++ + + P + R T +
Sbjct: 9288 NEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSW 9347
Query: 1214 --NGQQGNSLEEVVH---ADQSSCTFDNLSPGL----------EYNVSVYTVKDDKESVP 1258
+G+ ++++ VH D T +N S + +Y+++ K +++
Sbjct: 9348 EFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKN-KAGQKTAN 9406
Query: 1259 ISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEED-VAELSIS 1317
++ PP DL+ ++I + R++W P D + + Y K D A ++
Sbjct: 9407 CRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDD-DGGDRIKGYVIEKRTIDGKAWTKVN 9465
Query: 1318 P--SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL-------DSPTGIDFSD 1368
P V+ +LL +Y V + P+ Q+T D P +
Sbjct: 9466 PDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGL 9525
Query: 1369 ITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRED-RVPHSRN----SITLTNLT 1419
IT N+ + W P+ + +T Y + +G +E R + R+ T+ +L
Sbjct: 9526 ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLV 9585
Query: 1420 PGTEYVVSIVALN--GREESPLLIG-------QQSTVSDVPRDLEVVAATPTSLLIS-WD 1469
G EY + A+N G + +G D+ +EV T +++
Sbjct: 9586 EGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKG 9645
Query: 1470 APAVTVRYYRITYGETGGNSPVQEFT-----VPGSKSTATISGLKPGVDYTITVYAVTGR 1524
P T+ +++ + PV T V T I + T+ AV
Sbjct: 9646 VPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNL 9705
Query: 1525 GDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPK 1579
G +SK + +N P ++ V + +++ W P S +T Y +
Sbjct: 9706 G---TASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREA 9762
Query: 1580 NGPGPTKT---KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT--NI-- 1632
N KT ++ P + TI L EYV + AQN G +PL T N+
Sbjct: 9763 N----RKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFS 9818
Query: 1633 --DRPKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDT 1686
P + V +S+ + WE P+ V+ Y + +D + + + +
Sbjct: 9819 VPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGY---WLEMKDTTSKRWKRVNRDPIK 9875
Query: 1687 A-------ELQGLRPGSEYTVSVVALH------DDMESQPLIGTQSTAIPAPTDLKFTQV 1733
A ++ GL GS+Y V A++ + S P A P P K T
Sbjct: 9876 AMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDW 9935
Query: 1734 TPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 1789
T +S +W+PP ++TGY V + K K + + +VV+GL Y+
Sbjct: 9936 TKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYK 9995
Query: 1790 VSVYALKDTLTSRPAQGVVTTLEN----VSPPRR--ARVTD----------------ATE 1827
V A+ P + V +E VSP + A V D + +
Sbjct: 9996 FRVRAVNIAGIGEPGE-VTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGK 10054
Query: 1828 TTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDV--RSYTITGLQPGTDYKIYLYT 1885
T++W T+ P + TI+ S I Q L
Sbjct: 10055 PPPTVTWNMNERTL--------------PQEATIETTAISSSMVIKNCQRSHQGVYSLLA 10100
Query: 1886 LNDNARSSPVVIDASTAIDAPSNLRFLA--TTPNSLLVSWQPPR----ARITGYIIKYEK 1939
N+ +I + P FLA T S ++W P + IT Y+I EK
Sbjct: 10101 KNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVI--EK 10158
Query: 1940 PGSPPREVVPRPRPGVTE-ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLV 1998
S R P + AT+ GL G Y + IA +N+ P + + + + +
Sbjct: 10159 RESDRRAWTPVTYTVTRQNATVQGLIQGKAY-FFRIAAENSIGMGPFVETSEALVIREPI 10217
Query: 1999 TLPHPNLHGPEILDVPSTVQKTPFVT--HPGYDTGNGI 2034
T+P PE L+V + T +T P YD G+ I
Sbjct: 10218 TVP----ERPEDLEVKEVTKNTVTLTWNPPKYDGGSEI 10251
Score = 94.0 bits (232), Expect = 2e-18
Identities = 304/1555 (19%), Positives = 549/1555 (35%), Gaps = 206/1555 (13%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W P S I+ Y+L R +V K P + GL+ G YE ++ +I
Sbjct: 13009 VSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAI 13068
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW---- 740
+ G + + S + P V + T SS +SW
Sbjct: 13069 NKAGPGKPSD------------ASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPA 13116
Query: 741 VSASDTVSGFRVEYELSEEGDEPQYLDLPST--ATSVNIPDLLPGRKYIVNVYQISEDGE 798
+ G+ VE + + + D +LP T + L+ +Y VY +++ G
Sbjct: 13117 YDGGSPIIGYLVEVKRA-DSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIG- 13174
Query: 799 QSLILSTSQTTAPD--------APPDPTVDQVDDTSIVVR---WSRPQAPITGYRIVYSP 847
+ + PD PP+ +D ++++R R P+ G P
Sbjct: 13175 -----YSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRP---PP 13226
Query: 848 SVEGSSTELNLPETAN-SVTLSDLQPGV-----------QYNITIYAVEENQESTPVVIQ 895
+ S +NL + + +D + +Y +T+ +E T VV
Sbjct: 13227 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13286
Query: 896 QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHG 951
+T G P + TV E++ + W PP S + Y V
Sbjct: 13287 LDTPGPPVNVTVK--------EISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWST 13338
Query: 952 QRLPISRNTFAEVTGLSPGVTYYFKVFAVSH---GRESKPLTAQQTTKLDAP-TNLQFVN 1007
S+ +F V L G +Y+F+VFA + G + A + ++ P +L+ +
Sbjct: 13339 VTTECSKTSF-RVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRS 13397
Query: 1008 ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYT 1063
+ S+ + W P ++I GY + LT + ++ S+ +Y ++L EYT
Sbjct: 13398 VSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMKSLSL-QYSAKDLTEGKEYT 13455
Query: 1064 VSLVAIKGNQE-SPKATGVFT---TLQPG---SSIPPYNTEVTETT-----IVITWTPAP 1111
+ A N E +P V + P +P E + I I PAP
Sbjct: 13456 FRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAP 13515
Query: 1112 RIGFKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
+ +K G P + E ++ + +++V YTI + ++ I KV
Sbjct: 13516 SVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKV 13575
Query: 1171 VTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
V PT +T+ W + +IT Y + + + + V
Sbjct: 13576 VGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAV-- 13633
Query: 1228 DQSSCTFDNLSPGLEYNVSV-----YTVKDDKESVPI---SDTIIPAVPPPTDLRFTNIG 1279
+++ L G+EY V Y V + +S PI +P PPP ++ ++
Sbjct: 13634 QKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNI--VDVR 13691
Query: 1280 PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVA-----ELSISPSDNAVVLTNLLPGTEY 1334
D++ +TW P + + K + + I D V T L G EY
Sbjct: 13692 HDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV--TGLTEGLEY 13749
Query: 1335 VVSVSSVYEQHESTPLRGRQKT----GLDSPTGIDFSDITANSFTVHWIAPR----ATIT 1386
V ++ P + +D P + +IT NS T+ W P+ +T
Sbjct: 13750 EFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLT 13809
Query: 1387 GYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN--GREESPLLIGQQ 1444
GY + + + V + T+T+L G +Y I A N G +P +
Sbjct: 13810 GYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAP----SE 13865
Query: 1445 STVSDVPRDLEVVAATPTSLLISWDAPAVTVR----------------YYRITYGETGGN 1488
ST + + +D PT +L +T++ + ++ + G +
Sbjct: 13866 STETIICKD---EYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKD 13922
Query: 1489 SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQM 1548
+ T S T+++ +K Y +T + + + P +
Sbjct: 13923 IRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPV 13982
Query: 1549 QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
++++V ++ W P SP+ Y + + T + + +Q
Sbjct: 13983 EISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQG 14042
Query: 1605 TVEYVVSVYAQNPSGESQPLVQTAVTNIDR------PKGLAFTDVDVDSIKIAWESP--- 1655
EY+ V A N G+ +P+ V +DR P+ ++V ++ ++W+ P
Sbjct: 14043 N-EYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDD 14101
Query: 1656 -QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVA-----LHDDM 1709
+++ Y V + + ++ GL+ GS Y V A +
Sbjct: 14102 GGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPS 14161
Query: 1710 ESQPLIGTQSTAIP--APTDLKFTQVTPTSLSAQWTPPN----VQLTGYRVRVTPKEKTG 1763
E+ + + A P P++ T T S S W P+ +++TGY V +K G
Sbjct: 14162 EASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGY---VVEHQKVG 14218
Query: 1764 PMKEI----NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRR 1819
I A + VV L KY + A+ D PA V+ +E V
Sbjct: 14219 DEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPA--VIPDVEIVEREMA 14276
Query: 1820 ARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIK-------PDVRSYTITG 1872
E T+ R + PA T + I + S+T+
Sbjct: 14277 PDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTLLI 14336
Query: 1873 LQPGTDYKI--YLYTLNDNARSSPVVIDASTAIDAPS---NLRFLATTPNSLLVSWQPP- 1926
+ Y ++ T+ + A ++ +D P NLR T +S+ + W P
Sbjct: 14337 IPECNRYDTGKFVMTIENPAGKKSGFVNV-RVLDTPGPVLNLRPTDITKDSVTLHWDLPL 14395
Query: 1927 ---RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 1983
+RIT YI++ ++ + + +TGL G EY V+A E
Sbjct: 14396 IDGGSRITNYIVE-KREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGE 14454
Query: 1984 PLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPG 2038
P +T E + P P P+ L++ + T + P G ++ G
Sbjct: 14455 P----TETTEPVKASEAPSP----PDSLNIMDITKSTVSLAWPKPKHDGGSKITG 14501
Score = 93.6 bits (231), Expect = 2e-18
Identities = 287/1440 (19%), Positives = 522/1440 (36%), Gaps = 175/1440 (12%)
Query: 675 VVYEGQLISIQQYGHQEVTRFDFTTTSTS--TPVTSNTVTGETT--PFSPLVATSESVTE 730
+ E I++++ + R++ T ++S T N V + P P+V +++
Sbjct: 20030 ITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVV-----ISD 20084
Query: 731 ITASSFVVSWVSAS-DTVSGFRVEYELSEEGDEPQYLDLPSTA--TSVNIPDLLPGRKY- 786
IT S + W D S L E + ++ +T T + + L G +Y
Sbjct: 20085 ITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQ 20144
Query: 787 ----IVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYR 842
N + IS+ + + + T P P P V V SI V W P + G
Sbjct: 20145 FRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVS--NGGS 20202
Query: 843 IVYSPSVEGSSTELNLPETANSVTL-------SDLQPGVQYNITIYAVEENQESTPVVIQ 895
V +E L + AN + + + + G+ Y +YA P
Sbjct: 20203 AVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKP---S 20259
Query: 896 QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHG 951
+ D PR+++ +++ V++ W P S +TGY V+ +LP
Sbjct: 20260 HPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVE--RRDLPDGRW 20317
Query: 952 QRLPISRNTFAE--VTGLSPGVTYYFKVFAVSH-GRESKPL-TAQQTTKLDAPTNLQFVN 1007
+ + T + ++GL+ Y F+VFA + G S P T +D+
Sbjct: 20318 TKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDL 20377
Query: 1008 ETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--RQYNVGPSVSKYPLRNLQPASEYTVS 1065
+ T +V++ T +L G++ + P Y + L ++ ++
Sbjct: 20378 PLEYTEVVKYRAG----TSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASI 20433
Query: 1066 LV-------------AIKGNQESPKATGVFTTL-QPGSSIPPYNTE-VTETTIVITW-TP 1109
L+ ++ S AT L +PG P + VT I + W P
Sbjct: 20434 LIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPP 20493
Query: 1110 APRIGFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQVLR-----D 1158
A G K+ + E R V S + I + + G EY++ ++ + +
Sbjct: 20494 ADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGE 20553
Query: 1159 GQERDAPIV-NKVVTPLSP--PTNLHLEANPDTGVLTVSWERSTT---PDITGYRITTTP 1212
E D+ + N VTP P P + N +TV W R DI+GY +
Sbjct: 20554 PLESDSVVAKNAFVTPGPPGIPEVTKITKNS----MTVVWSRPIADGGSDISGYFLEKRD 20609
Query: 1213 TNGQQG-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV--------KDDKESVPISDTI 1263
L+E + + T L+ +Y V V + E +D I
Sbjct: 20610 KKSLGWFKVLKETIRDTRQKVT--GLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPI 20667
Query: 1264 IPAVPPPTDLRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEE-DVAELSISPS 1319
P PP +R + ++ + W+ P +T ++V + EE
Sbjct: 20668 DPP-GPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVR 20726
Query: 1320 DNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ----KTGLDSPTGIDFSDITANSFT 1375
V++NL PG Y VS+V + P+ + K L++P ID S
Sbjct: 20727 TTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPE-IDLDVALRTSVI 20785
Query: 1376 VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSI---------TLTNLTPGT--EY 1424
+ ++ R P + ++ +R SI T+ +T +Y
Sbjct: 20786 AKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKY 20845
Query: 1425 VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1484
+++I G +S + + + L+V + ++ + WD P + I Y
Sbjct: 20846 ILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 20905
Query: 1485 TGGNSPVQEFTVPGSKSTATISGL-----KPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
++ + ++V K ++T L K + + G G+ +++P+
Sbjct: 20906 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVK---A 20962
Query: 1540 TEIDKP-SQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594
E+ P + + D S+ + W S +T Y V + G G AG +
Sbjct: 20963 AEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVV---ERKGKGEQTWSHAGISK 21019
Query: 1595 T-EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFT-DVDVDSIKIAW 1652
T E+ + L+ V+A+N G S P+ +T K L T +VD+ I A
Sbjct: 21020 TCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPIT----VKELIITPEVDLSDIPGAQ 21075
Query: 1653 ESPQ-GQVSRYRVTY-SSPEDGIHEL---FPAPDGE-------EDTAELQGLRPGSEYTV 1700
+ + G + Y P+ I L P + E E+ L E+
Sbjct: 21076 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGG 21135
Query: 1701 SVVALHDDMESQPLIGTQSTAIPAPT----DLKFTQVTPTSLSAQWTPP----NVQLTGY 1752
+ D+ + + + P+ ++F ++ S+ W P ++T Y
Sbjct: 21136 KYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCY 21195
Query: 1753 RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLE 1812
+ +T K + + ++ V L+ +Y+ V A S+P + +
Sbjct: 21196 SIEKRETSQTN-WKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAK 21254
Query: 1813 N----VSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKP- 1863
+ PP + + + T ++++W +TGF V+ N + P
Sbjct: 21255 HQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPI 21314
Query: 1864 DVRSYTITGLQPGTDYKIYLYTLNDNARSSP----VVIDASTAIDAPSNLRFLATTPNSL 1919
R Y TGL G DY+ +Y N SSP A + +D P ++ T ++
Sbjct: 21315 SGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETI 21374
Query: 1920 LVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 1975
+ W PP ++I GY I+ ++ G+ + T+TGL PG Y +IA
Sbjct: 21375 TLKWNPPLRDGGSKIVGYSIE-KRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIA 21433
Score = 91.3 bits (225), Expect = 1e-17
Identities = 329/1588 (20%), Positives = 528/1588 (33%), Gaps = 253/1588 (15%)
Query: 589 CYGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPK 648
C R GE+ S + V + + + P P PI P H++ + W+P
Sbjct: 11076 CLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTG-PINILDVTPEHMT---ISWQPP 11131
Query: 649 NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQL-----ISIQQYGHQEVTRFDFTTTSTS 703
G I + + GVV G I Q G + V R
Sbjct: 11132 KDDGG--SPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGV 11189
Query: 704 TPVTSNTVTGETTPFSPLVATSESV-TEITASSFVVSWV----SASDTVSGFRVEYELSE 758
P +T T FSP + V T+IT ++ VSW ++G+ +E
Sbjct: 11190 GPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERR-EV 11248
Query: 759 EGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTA--PDAPPD 816
G + P + L G Y V+ + G S+ A P PP
Sbjct: 11249 TGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPG 11308
Query: 817 PTV-----DQVDDTSIVVRWSRPQA----PITGYRIVYSPSVEGSSTELNLPETANSVT- 866
P + D+ +T+ +V W++P + PI GY + +N E
Sbjct: 11309 PPINPKLKDKSRETADLV-WTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQCAF 11367
Query: 867 -LSDLQPGVQYNITIYAVE-----ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTD 920
+ L G +Y I A E +E VI ++ P + + RD+ V V
Sbjct: 11368 RVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRVGQ 11427
Query: 921 V-----------KVTIMWTPPESA-VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLS 968
+ I WT V RVD+I Q LP E
Sbjct: 11428 TIRILARVKGRPEPDITWTKEGKVLVREKRVDLI---------QDLPRVELQIKEAVRAD 11478
Query: 969 PGVTYYFKVFAVSHGRESKPLTAQQTTKLDAP---TNLQFVNETDSTVLVRWTPPRAQIT 1025
G + H + S + LD P NL+ N T + W P
Sbjct: 11479 HGKYIISAKNSSGHAQGSAIVNV-----LDRPGPCQNLKVTNVTKENCTISWENPLDN-G 11532
Query: 1026 GYRLTVGLTRRGQPRQYN---VGPSVSKYPLR-NLQPASEYTVSLVAIKGNQESPKATGV 1081
G +T + +P Q V V+K ++ NL +EY + A GV
Sbjct: 11533 GSEITNFIVEYRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCA-------ENKVGV 11585
Query: 1082 FTTLQPGSSI----------PPYNTEVTE---TTIVITWTP------APRIGFKLG--VR 1120
T++ + I P N + + T + + W +P + + + ++
Sbjct: 11586 GPTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLK 11645
Query: 1121 PSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP---LSPP 1177
S E + + +V Y + +Q +G E D +VV P
Sbjct: 11646 GSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPV 11705
Query: 1178 TNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNL 1237
+L L +GVLTV G I G +G EV T
Sbjct: 11706 LDLKL-----SGVLTVK---------AGDTIRLEA--GVRGKPFPEVAWTKDKDATDLTR 11749
Query: 1238 SPGLEYNVSVYTVKDDKESVPISD---------------------TIIPAVPPPTDLRFT 1276
SP ++ + + K SD ++ P +L+
Sbjct: 11750 SPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIV 11809
Query: 1277 NIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTE 1333
++ D V W PP ++ N+++ K + S + +T L+ G E
Sbjct: 11810 DVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMV-WSTYSATVLTPGTTVTRLIEGNE 11868
Query: 1334 YVVSVSSVYEQHESTPLRGRQ---KTGLDSPTGIDFSDITANS---FTVHWIAPR----A 1383
Y+ V + + P + KT D P D ++T S TV W P
Sbjct: 11869 YIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGK 11928
Query: 1384 TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN-------GREE 1436
+ITGY + +H + ++ + + NL P EY + A N
Sbjct: 11929 SITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPS 11988
Query: 1437 SPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP-----AVTVRYYRITYGETGGNSPV 1491
P++ P + VV T S+ + W P A + Y + SP
Sbjct: 11989 RPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPD 12048
Query: 1492 QEFTVPGS-----KSTATISGLKPGVDYTITVYAVTGRG-DSPASSKPISINYRTEIDKP 1545
+ + + + T++ L +Y V A G PA K E KP
Sbjct: 12049 EGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELK--------EAIKP 12100
Query: 1546 SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKT-KTAGPDQTEMTIE-GLQ 1603
++ D S++ L R+ + P P T + G D + L
Sbjct: 12101 KEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLV 12160
Query: 1604 PTVEYVV------------SVYAQNPSGESQPLVQTAVTNIDRP-KGLAFTDVDVDSIKI 1650
T+ ++V S+ NP+GE V V + P L +DV S +
Sbjct: 12161 DTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHV 12220
Query: 1651 AWESPQG----QVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH 1706
+W P+ QV+ Y V + P+ ++ + + L PG+EY V A++
Sbjct: 12221 SWAPPENDGGSQVTHYIVEKREADRKTWSTV-TPEVKKTSFHVTNLVPGNEYYFRVTAVN 12279
Query: 1707 D-------DMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP--------NVQLTG 1751
+ D+ L + P L+ T++T S + W PP + +T
Sbjct: 12280 EYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITS 12339
Query: 1752 YRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP--AQGVVT 1809
YR P ++ E ++ D S +VV+GL KY+ V A S P A+GV
Sbjct: 12340 YREEEQPADR---WTEYSVVKDLS-LVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYE 12395
Query: 1810 TLENVSPPRRARVTDAT---------------ETTITISWRT-KTETITGFQVDAVPANG 1853
E + PP+ T + T W+ + E +T + A+
Sbjct: 12396 AKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADS 12455
Query: 1854 QTP--IQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRF 1911
+ I+ + D Y++T D + VV+DA P ++
Sbjct: 12456 SSILIIKDVTRKDSGYYSLTAENSSG---------TDTQKIKVVVMDAPGPPQPPFDISD 12506
Query: 1912 LATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGT 1967
+ SL SW P + IT YI++ + S V T + L PG
Sbjct: 12507 IDADACSL--SWHIPLEDGGSNITNYIVE-KCDVSRGDWVTALASVTKTSCRVGKLIPGQ 12563
Query: 1968 EYTIYVIALKNNQKSEPLIGRKKTDELP 1995
EY V A SEPL K + P
Sbjct: 12564 EYIFRVRAENRFGISEPLTSPKMVAQFP 12591
Score = 90.9 bits (224), Expect = 1e-17
Identities = 273/1318 (20%), Positives = 459/1318 (34%), Gaps = 189/1318 (14%)
Query: 771 TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP---DPTVDQVDDTSI 827
++TS + DL + V +E G +T A + P D ++ TS+
Sbjct: 20923 SSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSV 20982
Query: 828 VVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAV 883
++ W++P + IT Y + E + + + +T + +S L+ ++A
Sbjct: 20983 ILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTCE-IEVSQLKEQSVLEFRVFAK 21041
Query: 884 EENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIP 943
E S PV I T + + +P ++ ++ +VT+ Y+ P
Sbjct: 21042 NEKGLSDPVTIGPITV----KELIITP-EVDLSDIPGAQVTVRIGHNVHLELPYKGKPKP 21096
Query: 944 VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN- 1002
+ G LP+ + F + +T K HG + + ++ P
Sbjct: 21097 SISWLKDG--LPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITV 21154
Query: 1003 ------------LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP 1046
++F +V++ W P +IT Y + T + +
Sbjct: 21155 ITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSV 21214
Query: 1047 SVSKYPLRNLQPASEYTVSLVAI-KGNQESPKATGVFTTLQ----PGSSIPPYNTEVTET 1101
+ + + + NL +EY + A + P + + PG P VT
Sbjct: 21215 ARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSD 21274
Query: 1102 TIVITWTP------APRIGFKLGVRPSQGGEAPREVTSD-SG-SIVVSGLTPGVEYVYTI 1153
+ +TW + GF + + + TS SG +GL G++Y + +
Sbjct: 21275 GMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRV 21334
Query: 1154 QVLRDG---QERDAPIVNKVVTPLSPP-TNLHLEANPDTGVLTVSWE---RSTTPDITGY 1206
D V+P+ PP T +++ +T +T+ W R I GY
Sbjct: 21335 YAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRET--ITLKWNPPLRDGGSKIVGY 21392
Query: 1207 RITTTPTNGQQGNSL-EEVVHADQSSC--TFDNLSPGLEYNV------SVYTVKDDKESV 1257
I +QGN D S C T LSPG Y +V T+ +S
Sbjct: 21393 SIEK-----RQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSS 21447
Query: 1258 PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAEL 1314
I T VPP GP+ LV+ PV +D E+
Sbjct: 21448 GIIMTRDENVPP-----IVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEI 21502
Query: 1315 SISPSDNAVVLTNLLPGTEYVV--------SVSSVYEQHESTPLRGRQKTGLDSPTG--- 1363
+ + +T++L T V V +V ++ S + K + G
Sbjct: 21503 EKRMN---MEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVV 21559
Query: 1364 --IDFSDITANSFTVHWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLT 1416
I F++IT T+ W AP A IT Y I + + ED+ S T
Sbjct: 21560 GPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC--EAQSYTAI 21617
Query: 1417 NLTPGTEYVVSIVALN----GR--EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
L G EY + A+N GR + P++ Q TV D P E T S+ ++W
Sbjct: 21618 KLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWAR 21677
Query: 1471 PAVTVRYYRITYGETGGNSPVQEFTV-----------------PGSKSTATISGLKPGVD 1513
P E+ G S +Q++ + P S++ ++GL G +
Sbjct: 21678 P------------ESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNE 21725
Query: 1514 YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ---MQVTDVQDNSISVKW----LPSS 1566
Y V A G PAS I R ++ P ++VTD ++S++W
Sbjct: 21726 YEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGG 21785
Query: 1567 SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ 1626
+ GY + + K +T T+ LQ EY V A N +G+
Sbjct: 21786 MEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEV 21845
Query: 1627 TA-VTNIDRPKGLAFTDVDVDS-IKIAWESPQGQVSRYRVTY----------SSPEDGIH 1674
T + +DR L ++D+D+ K G R + Y S P+ +
Sbjct: 21846 TGTIKAVDR---LTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLS 21902
Query: 1675 ---ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFT 1731
++ T E +YT++V + T P P + F
Sbjct: 21903 LRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP-PGPITFK 21961
Query: 1732 QVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE----INLAPDSSSVVVSGLMVATK 1787
VT S + W P + G R+ EK + I+ V+ L
Sbjct: 21962 DVTRGSATLMWDAPLLD-GGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVP 22020
Query: 1788 YEVSVYALKDTLTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISW----RTKTETI 1841
Y V A+ + P + + E +PPRR V D ++++ ++W I
Sbjct: 22021 YYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRI 22080
Query: 1842 TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1901
TG+ ++ ++ + ++T+ L T+Y+ + ND S P +S
Sbjct: 22081 TGYLLEMRQKGSDFWVEAGHTKQL-TFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSV 22139
Query: 1902 AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP---RPRPGVT 1956
I P P + L IT +I K GSP VP RP P VT
Sbjct: 22140 IIKEPQ------IEPTADLTG-------ITNQLITC-KAGSPFTIDVPISGRPAPKVT 22183
Score = 90.1 bits (222), Expect = 2e-17
Identities = 343/1758 (19%), Positives = 611/1758 (34%), Gaps = 294/1758 (16%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W P S I YI+ R + + W S + L G Y +++++
Sbjct: 16159 LAWKPPLQDGGSDIINYIVERRETSRLV-WTVVDANVQTLSCKVTKLLEGNEYTFRIMAV 16217
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVS-A 743
+YG E P+ S V + P + VT +T S +V W A
Sbjct: 16218 NKYGVGE-------------PLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPA 16264
Query: 744 SD---TVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKY-----IVNVYQISE 795
SD + G+ +E E + + + L+ Y N +SE
Sbjct: 16265 SDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSE 16324
Query: 796 DGEQSLILSTSQTTAPDAPPD-PTVDQVDDTSIVVRWSRP----QAPITGYRIVYSPSVE 850
S PP+ P V + +S+ + WS+P I GY +
Sbjct: 16325 PSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSV 16384
Query: 851 GSSTELNLPETAN--SVTLSDLQPGVQYNITIYAVE-----ENQESTPVVIQQETTGTPR 903
G T P N ++ + L +YN I A+ E+ + +I +E P
Sbjct: 16385 GEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPD 16444
Query: 904 SDTVPSPRDLQFVEVTDVK--------VTIMWTP-PE---SAVTGYRVDVIPVNLPGEHG 951
D DL+ ++ +++ V I P PE V G D +++
Sbjct: 16445 IDL-----DLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFT 16499
Query: 952 QRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDS 1011
+ + N + Y S G +S +T + P NL+ T
Sbjct: 16500 SLVLDNVNRYDSGK--------YTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKD 16551
Query: 1012 TVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLV 1067
+V + W PP ++I Y + R + + + LQ Y +
Sbjct: 16552 SVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVT 16611
Query: 1068 A-----IKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIG------FK 1116
A I ++ V QP I +VT ++ ++WT G +
Sbjct: 16612 AENEYGIGLPAQTADPIKVAEVPQPPGKITV--DDVTRNSVSLSWTKPEHDGGSKIIQYI 16669
Query: 1117 LGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERD-----APIVNK-- 1169
+ ++ + S V++ LT G EY++ + + + D PIV K
Sbjct: 16670 VEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDL 16729
Query: 1170 VVTPLSPP--TNLHLEANPDTGVL---------TVSWERSTTPDITGYRITTTPTNGQQG 1218
V+ P P ++ ++ D + T++W + P RI T +
Sbjct: 16730 VIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTT 16789
Query: 1219 NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNI 1278
S++E H D G +Y ++V V K + T+ PP ++F ++
Sbjct: 16790 LSIKET-HKDD----------GGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDV 16838
Query: 1279 GPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEE-DVAELSISPSDNAVVLTNLLPGTEY 1334
+++ ++W PP +TN++V+ DV +++ + + +T L GTEY
Sbjct: 16839 SAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVART--TLKVTKLKTGTEY 16896
Query: 1335 VVSV--SSVYEQH---ESTPLRGRQKTGLDSPTGIDFSD-ITANSFTVHWIAP----RAT 1384
+ + Y Q ES P+ + P G F+ I+ +S + W P +
Sbjct: 16897 QFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSP 16956
Query: 1385 ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQ 1444
+ GY + + + ++ NL G EY + A E+ + +G+
Sbjct: 16957 VIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYA-----ENIVGVGKA 17011
Query: 1445 STVSD--VPRDLEVVAATPTSLLISWDAPAVTVRYYRITY--GETGGNSPVQEFTVPGSK 1500
S S+ V RD TP +++ + +T+++ + Y G V++ +P +
Sbjct: 17012 SKNSECYVARDPCDPPGTPEPIMVKRNE--ITLQWTKPVYDGGSMITGYIVEKRDLPDGR 17069
Query: 1501 -----------STATISGLKPGVDYTITVYAVTGRGDSPASSKPIS----INYRTEIDKP 1545
+ T+SGL Y V A G A SKP I + E++ P
Sbjct: 17070 WMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAG---AISKPSDSTGPITAKDEVELP 17126
Query: 1546 SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPT 1605
+D + + +R+ P PT G + E +
Sbjct: 17127 RISMDPKFRDTIVV-------NAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKN 17179
Query: 1606 VEYVVSVY---------------AQNPSGESQPLVQTAVTNIDRPKG----LAFTDVDVD 1646
++ + A N +G V V +DRP + T V +
Sbjct: 17180 TDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKV--LDRPGPPEGPVQVTGVTSE 17237
Query: 1647 SIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSV 1702
+ W P +S Y V + A + ++ ++ L G+EY +
Sbjct: 17238 KCSLTWSPPLQDGGSDISHY-VVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRI 17296
Query: 1703 VALH-----DDMESQPLIGTQSTAIPAPT-DLKFTQVTPTSLSAQWTPPNV----QLTGY 1752
+A++ + +ES P++ +P P L+ T + S++ W P+ ++ GY
Sbjct: 17297 MAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGY 17356
Query: 1753 RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVV---- 1808
V + +K + V+GL +YE V A P+ V
Sbjct: 17357 IVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKA 17416
Query: 1809 -TTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKP 1863
+ PP A + D T+ +IT++W I G+ V+ A+ + + + P
Sbjct: 17417 CDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEE--WQIVTP 17474
Query: 1864 D----VRSYTITGLQPGTDYKIYLYTLN----DNARSSPVVIDASTAIDAPSNLRFLATT 1915
V + I+ L +YKI + LN A S P + ++AP L +
Sbjct: 17475 QTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAP-ELDLDSEL 17533
Query: 1916 PNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP---RPRPGVTEATITG-------LEP 1965
++V + G R +P RP P +T + G +E
Sbjct: 17534 RKGIVV-----------------RAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEK 17576
Query: 1966 GTEYT-------------IYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILD 2012
G YT Y++ L+N+ S+ K + P P NL E+
Sbjct: 17577 GVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPG----PPQNLAVKEVRK 17632
Query: 2013 VPSTVQKTPFVTHPGYDTGNGI----------------QLPGTSGQQPSVGQQMIF---- 2052
+ + P + G N + + TS + ++ + I+
Sbjct: 17633 DSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRV 17692
Query: 2053 -EEHGFRRTTPPTTATPIRHRPRPYPP-NVGQEALSQTTIS--W-APFQDTSE----YII 2103
E+ F P T ++ P PP V +SQT+ S W P D Y++
Sbjct: 17693 MAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVV 17752
Query: 2104 SCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSV 2163
P GT E +A +TGL+ G Y V+A ++ + R V+ V
Sbjct: 17753 EMQPKGT--EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPR--VLGVPVIA 17808
Query: 2164 NEGLNQPTDDSCFDPYTV 2181
+ QP+ F+ Y++
Sbjct: 17809 KDLTIQPSLKLPFNTYSI 17826
Score = 89.7 bits (221), Expect = 3e-17
Identities = 260/1286 (20%), Positives = 475/1286 (36%), Gaps = 231/1286 (17%)
Query: 780 LLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPIT 839
++P ++Y++ V ++ G + A D PT+D IV+ + P+
Sbjct: 7853 VVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVP 7912
Query: 840 GYRIVYSPSV----EGSSTELNLPETANSVTLS---DLQPGVQYNITIYAV--EENQEST 890
+R V P+V +G + + T + +S ++ V+ + IY + E S
Sbjct: 7913 -FRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSA 7971
Query: 891 PVVIQQETTGTPRSDTVPSP-RDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGE 949
I + G +P P +D++ ++T + W PPE G + V E
Sbjct: 7972 TASINVKVIG------LPGPCKDIKASDITKSSCKLTWEPPE--FDGGTPILHYVLERRE 8023
Query: 950 HGQR--LPI--SRNTFA-EVTGLSPGVTYYFKVFAVSH--GRE----SKPLTAQQTTKL- 997
G+R +P+ N + V L P Y+F+V AV+ G E P+ AQ +
Sbjct: 8024 AGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPP 8083
Query: 998 DAPTNLQFVNETDSTVLVRWTPPR----AQITGY---RLTVGLTRRGQPRQYNVGPSVSK 1050
D P +++ N T + + W PP ++I GY ++ G R + ++ V +
Sbjct: 8084 DPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLV--PILT 8141
Query: 1051 YPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
Y + L+ EY + A A G+ +P + PP T + A
Sbjct: 8142 YTAKGLEEGKEYQFRVRA-------ENAAGIS---EPSRATPP--------TKAVDPIDA 8183
Query: 1111 PRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVL--RDGQERDAPIVN 1168
P++ + + +G E + S SGS P + ++ V+ + ++R AP+V
Sbjct: 8184 PKVILRTSLEVKRGDEIALDA-SISGSPY-----PTITWIKDENVIVPEEIKKRAAPLVR 8237
Query: 1169 KVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHAD 1228
+ + L P T L++ N ++G S V
Sbjct: 8238 RRKGEVQEEEPFVL---PLTQRLSID-------------------NSKKGESQLRVR--- 8272
Query: 1229 QSSCTFDNLSPGLEYNVSVYTVKDDK--ESVPISDTIIPAVPPPTDLRFTNIGPDTMRVT 1286
D+L P ++ + + V++D P + +++ PP + F +I ++
Sbjct: 8273 ------DSLRP--DHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCK 8324
Query: 1287 WAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE 1346
W PP D + ++ Y+ K ++ P +V+T+ L +Y SV+ + E E
Sbjct: 8325 WEPPLD-DGGSEIINYTLEKKDKT------KPDSEWIVVTSTLRHCKY--SVTKLIEGKE 8375
Query: 1347 ------------------STPLRGRQKTGL-DSPTGIDFSDITANSFTVHWIAPR---AT 1384
S PL + G D+P D+T+NS V W P+ +
Sbjct: 8376 YLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSP 8435
Query: 1385 ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLL 1440
I GY + + + R ++ + + L G YV + A N G+ P
Sbjct: 8436 ILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPP-- 8493
Query: 1441 IGQQSTVSD--------VPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGN 1488
T D +PR V + T++ + W+ PA + Y + G N
Sbjct: 8494 -SDPKTAHDPISPPGPPIPR---VTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTN 8549
Query: 1489 SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEIDKPSQ 1547
+ T+ ++ G DY + V AV G+ P ++P+++ E +P
Sbjct: 8550 EWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQPVTV---AEPQEPPA 8606
Query: 1548 MQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTK--TKTAGP-DQTEMTIEGLQP 1604
+++ +SVK R+ P PTK TK G D+ + I+ +
Sbjct: 8607 VEL------DVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGT 8660
Query: 1605 TVEYVVS-----------VYAQNPSGESQPLVQTAVTNIDRP-KGLAFTDVDVDSIKIAW 1652
E ++ + A N G + V ++ P L + + W
Sbjct: 8661 KSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNW 8720
Query: 1653 ESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH-- 1706
P+ +++ + + + +H + E ++ GL G EY V+A +
Sbjct: 8721 SDPEDDGGSEITGFIIERKDAK--MHTWRQPIETERSKCDITGLLEGQEYKFRVIAKNKF 8778
Query: 1707 ---DDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTP 1758
+E P++ P +P L +T+ T ++++ W P + GY +
Sbjct: 8779 GCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRR 8838
Query: 1759 KEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPA--QGVVTTLENVSP 1816
+K + ++S +V L YE V A+ + S P+ VV + V P
Sbjct: 8839 HDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPP 8898
Query: 1817 PRRARVTDATETTIT-------------------ISWRTKTETITGFQVDAVPANGQTPI 1857
+ R++ +T I W +K ET+ DA+ +
Sbjct: 8899 TIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEW-SKNETVIEKPTDALQITKEEVS 8957
Query: 1858 QRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI-DAPSNLRFLATT- 1915
+ K ++ GT YT+ + R V + + D PS R LA T
Sbjct: 8958 RSEAKTELSIPKAVREDKGT------YTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTD 9011
Query: 1916 --PNSLLVSWQPP----RARITGYII 1935
S ++W P + IT Y+I
Sbjct: 9012 IKAESCYLTWDAPLDNGGSEITHYVI 9037
Score = 87.4 bits (215), Expect = 1e-16
Identities = 347/1579 (21%), Positives = 545/1579 (34%), Gaps = 257/1579 (16%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W +P+ S I+ Y++ R + W T + T++GL G Y ++ +
Sbjct: 10138 LTWFSPEDDGGSPITNYVIEKRESDRRA-WTPVTYTVTRQNATVQGLIQGKAYFFRIAAE 10196
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
G F TS + + T P P V E+T ++ ++W
Sbjct: 10197 NSIGMGP-----FVETSEALVIREPI----TVPERP---EDLEVKEVTKNTVTLTWNPPK 10244
Query: 745 DTVSGFRVEYELSEE--GDEPQYLDLPSTATS--VNIPDLLPGRKYIVNVYQISEDGEQS 800
+ Y L G E + S + L G Y V ++ G+
Sbjct: 10245 YDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGK 10304
Query: 801 LILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPE 860
T T D PT+ + +R A Y P V E ++ E
Sbjct: 10305 PSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 10364
Query: 861 TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET---TGTPRSDTVPSPRD----L 913
+ T P I A + VV++ T G + + V P +
Sbjct: 10365 --DDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPV 10422
Query: 914 QFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI---SRNTFAEVTG 966
F EVT + I W PP S +T Y ++ V +P+ S T +V+
Sbjct: 10423 SFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVG----KDVWMPVTSASAKTTCKVSK 10478
Query: 967 LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD------APTNLQFVNETDSTVLVRWTPP 1020
L G Y F++ A + S PL + D AP T + LV W P
Sbjct: 10479 LLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP 10538
Query: 1021 R---AQITGYRLTVGLTRRGQPRQYNVGP--SVSKYPLRNLQPASEYTVSLVA---IKGN 1072
IT Y L T + + P +K+ + +L +Y + A I
Sbjct: 10539 HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIG 10598
Query: 1073 QESPKATGVFTTLQPGSSIPPYNTEVTETT---IVITWTPAPR-------IGFKLGVRPS 1122
SP + VF PP N E +TT + +TW P PR +G+ + +
Sbjct: 10599 DPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQP-PRHDGGSKILGYIVEYQ-K 10656
Query: 1123 QGGEAPREVTSDSGSIV-----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP---L 1174
G E R S V+GL G Y + + + E D V + V L
Sbjct: 10657 VGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRL 10716
Query: 1175 SPPTNLHLEANP---------DTGVLT----------VSWERSTTPDITGYRITTTPTNG 1215
PP L L+AN DT L+ V+W++ T RI TP
Sbjct: 10717 EPP-ELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS 10775
Query: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRF 1275
+ + H D + +P VSV + DK PP DL
Sbjct: 10776 KL--EIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG------------PPRDLEV 10821
Query: 1276 TNIGPDTMRVTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332
+ I D+ +TW P +TN++V V + + + LS + + +L G
Sbjct: 10822 SEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ-WSPLSATSKKKSHFAKHLNEGN 10880
Query: 1333 EYVVSVSSVYEQHESTPLRGRQKT--GLDS------PTGIDFSDITANSFTVHWIAPR-- 1382
+Y+ V++ Q+ P K LD P + D+ ++ W P
Sbjct: 10881 QYLFRVAAE-NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRD 10939
Query: 1383 --ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREE 1436
+ ITGY + + E + V + +T L G Y + A N G +
Sbjct: 10940 GGSPITGYLVEYQEEGTQDWIKFKTVTNLE--CVVTGLQQGKTYRFRVKAENIVGLGLPD 10997
Query: 1437 SPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTV 1496
+ + I Q + VP +E+ L++ TVR+ I G P ++T
Sbjct: 10998 TTIPIECQEKL--VPPSVELDVKLIEGLVVK---AGTTVRFPAIIRGVP---VPTAKWTT 11049
Query: 1497 PGSK---------------STATISGL--KPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
GS+ S TI + +Y ITV + A SK ++++
Sbjct: 11050 DGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV-------SNAAGSKTVAVHL- 11101
Query: 1540 TEIDKPSQ----MQVTDVQDNSISVKWLP----SSSPVTGYRVTT--TPKNGPGPTKTKT 1589
T +D P + + DV +++ W P SPV Y V T K+ G +
Sbjct: 11102 TVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVV---S 11158
Query: 1590 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR------PKGLAFTDV 1643
+G +T++ I LQ EYV V A+N G PL T + P TD+
Sbjct: 11159 SGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDI 11218
Query: 1644 DVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQ----GLRPGSEYT 1699
++ ++W P+ Y + + + + A+L+ GL G+ Y
Sbjct: 11219 TENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVN-KTPIADLKFRVTGLYEGNTYE 11277
Query: 1700 VSVVALH------DDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPP----NVQ 1748
V A + S P+ + P P + K + + WT P
Sbjct: 11278 FRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSP 11337
Query: 1749 LTGYRVRVTPKEKTGPMKEINLAP--DSSSVVVSGLMVATKYEVSVYALKDTLTSRP--- 1803
+ GY V K T IN + V GL+ +Y + A P
Sbjct: 11338 ILGYVVE-CQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPREL 11396
Query: 1804 AQGVVTTLENVSPPR-------RARVTDATETTITISWRTK-------TETITG------ 1843
A+ V+ + + PP R +T TI I R K T T G
Sbjct: 11397 AESVIAK-DILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVRE 11455
Query: 1844 FQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI 1903
+VD + + +Q IK VR+ Y I + +A+ S +V +
Sbjct: 11456 KRVDLIQDLPRVELQ--IKEAVRA-------DHGKYIISAKNSSGHAQGSAIV----NVL 11502
Query: 1904 DAP---SNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVT 1956
D P NL+ T + +SW+ P + IT +I++Y KP +V VT
Sbjct: 11503 DRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIV---ASDVT 11559
Query: 1957 EATI-TGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPS 2015
+ I L EY V A +N P I K P L P PE L +
Sbjct: 11560 KRLIKANLLANNEYYFRVCA-ENKVGVGPTIETK----TPILAINPIDRPGEPENLHIAD 11614
Query: 2016 TVQKTPFV--THPGYDTGN 2032
+ ++ P YD G+
Sbjct: 11615 KGKTFVYLKWRRPDYDGGS 11633
Score = 85.5 bits (210), Expect = 6e-16
Identities = 330/1597 (20%), Positives = 570/1597 (35%), Gaps = 278/1597 (17%)
Query: 737 VVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQ 792
+++W D ++GF +E + ++ Q ++ + + +I LL G++Y V
Sbjct: 8717 LLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIE--TERSKCDITGLLEGQEYKFRVIA 8774
Query: 793 ISEDG-----EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQA----PITGYRI 843
++ G E IL+ P +P T + ++I + W P++ PI GY I
Sbjct: 8775 KNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYII 8834
Query: 844 VY----SPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTP-----VVI 894
P E + L P T S + +L Y + AV E ES P VVI
Sbjct: 8835 EKRRHDKPDFERVNKRL-CPTT--SFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVI 8891
Query: 895 QQETTG-------TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLP 947
Q + + R DT+ ++ E + + P VI
Sbjct: 8892 QDDEVPPTIKLRLSVRGDTIK----VKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTD 8947
Query: 948 GEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH----GRESKPLTAQQTTKLDAPTNL 1003
+ +SR+ + V + V+ G + + + + P NL
Sbjct: 8948 ALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNL 9007
Query: 1004 QFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV--SKYPLRNLQ 1057
+ + + W P ++IT Y + R + V + +Y + L
Sbjct: 9008 AVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLI 9067
Query: 1058 PASEYTVSLVAIKGNQESPKATGVFTTLQ-----PGSSIPPYNTEVTETTIVITWTP--- 1109
P +Y + A+ S + +Q PG P T+ +++++WTP
Sbjct: 9068 PNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLD 9127
Query: 1110 ---APRIGFKLGVRP------SQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVLR-- 1157
+P G+ L R S+ AP G V L GV+Y + +
Sbjct: 9128 NGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAA 9187
Query: 1158 ----DGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE---RSTTPDITGYRITT 1210
+ D + + P PP+ ++ + + ++ W+ + I GY +
Sbjct: 9188 GIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSI-SLGWKPPAKDGGSPIKGYIVEM 9246
Query: 1211 TP---TNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAV 1267
T+ ++ N ++++ + C NL +Y V V + ES P SDT
Sbjct: 9247 QEEGTTDWKRVNEPDKLITTCE--CVVPNLKELRKYRFRVKAVNEAGESEP-SDTT--GE 9301
Query: 1268 PPPTDLR-----FTNIGPDTMRVTWA-------------PPPS----IDLTNFLVRYSPV 1305
P TD++ F +IG V A P P D V
Sbjct: 9302 IPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGV 9361
Query: 1306 KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP-LRGRQKTGLDSPTGI 1364
+ + A+L + + + +++ S+++ + + T R + P +
Sbjct: 9362 HDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDL 9421
Query: 1365 DFSDITANSFTVHWIAPRAT----ITGYRIRHHPEHFSGRPREDRVPH-SRNSITLTNLT 1419
SDIT S + W P I GY I G+ P + + +L
Sbjct: 9422 KVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRT--IDGKAWTKVNPDCGSTTFVVPDLL 9479
Query: 1420 PGTEYVVSIVALNGREESPLLIGQQSTVS-------DVPRDLEVVAATPTSLLISWDAPA 1472
+Y + A N P + Q T + D P L++ T ++ +SW P
Sbjct: 9480 SEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPP- 9538
Query: 1473 VTVRYYRITYGETGGNSPVQEFTVP-------GSKSTA--------------TISGLKPG 1511
+ G SPV + V G+K A T+ L G
Sbjct: 9539 -----------KNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEG 9587
Query: 1512 VDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTG 1571
+Y V AV G S S+ P Q D+ SI +K T
Sbjct: 9588 GEYEFRVKAVNAAGVSKPSATV----------GPCDCQRPDMPP-SIDLKEFMEVEEGTN 9636
Query: 1572 YRVTTTPKNGPGPT----KTKTAGPDQTEMTIEGLQPTVEYV----VSVYAQNPSGESQP 1623
+ K P PT K PD E + V V Q+ ++
Sbjct: 9637 VNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGL 9696
Query: 1624 LVQTAVTNIDR---------------PKG-LAFTDVDVDSIKIAWESPQ----GQVSRYR 1663
TAV N+ P G + F V D + ++W P+ +++ Y
Sbjct: 9697 YTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYV 9756
Query: 1664 VTY--SSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVA-----LHDDMESQPLIG 1716
+ ++ + +H + + +E T + L G EY ++A + + ++S+P
Sbjct: 9757 IEKREANRKTWVHV---SSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETA 9813
Query: 1717 TQSTAIP-APTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPM-KEINL 1770
++P AP + VT S++ W P +TGY + + K+ T K +N
Sbjct: 9814 RNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEM--KDTTSKRWKRVNR 9871
Query: 1771 APDSS-----SVVVSGLMVATKYEVSVYALKD------TLTSRPAQGVVTTLENVSPPRR 1819
P + S V+GL+ + Y+ VYA+ +L S PA T + ++PP
Sbjct: 9872 DPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPA----TARDPIAPPGP 9927
Query: 1820 A--RVTDATETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRS--YTIT 1871
+VTD T+++ + W + +TG+ V+ G+ ++ +VR +T
Sbjct: 9928 PFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVE-YKEEGKEEWEKGKDKEVRGTKLVVT 9986
Query: 1872 GLQPGTDYKIYLYTLNDNARSSPV----VIDASTAIDAPSNLRFLATTPNSLLVSWQPPR 1927
GL+ G YK + +N P VI+ + +P +L+ A+ + ++V
Sbjct: 9987 GLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSP-DLQLDASVRDRIVVH-AGGV 10044
Query: 1928 ARITGYIIKYEKPGSPPREVV--PRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP- 1984
RI Y+ G PP V R EATI T + +KN Q+S
Sbjct: 10045 IRIIAYV-----SGKPPPTVTWNMNERTLPQEATIE-----TTAISSSMVIKNCQRSHQG 10094
Query: 1985 ---LIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQL----P 2037
L+ + + E + + + ++LDVP V TPF+ H T +L P
Sbjct: 10095 VYSLLAKNEAGERKKTIIV--------DVLDVPGPVG-TPFLAHNL--TNESCKLTWFSP 10143
Query: 2038 GTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQ----EALSQTTISWA 2093
G P + +I + RR P T T R G+ ++ +I
Sbjct: 10144 EDDGGSP-ITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMG 10202
Query: 2094 PFQDTSEYIISCHPVGTDEEPLQFRVPG-TSTSATLT 2129
PF +TSE ++ P+ E P V T + TLT
Sbjct: 10203 PFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLT 10239
Score = 85.5 bits (210), Expect = 6e-16
Identities = 343/1679 (20%), Positives = 586/1679 (34%), Gaps = 264/1679 (15%)
Query: 611 PVEVFITETPSQPNSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNS-Y 666
P V +T+T S ++W+ P I YI+ K +G W + + + Y
Sbjct: 21760 PTVVKVTDTSKTTVS--LEWSKPVFDGGMEIIGYIIEMC-KADLGDWHKVNAEACVKTRY 21816
Query: 667 TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
T+ L+ G Y+ ++ +I G + S T V T P + A +
Sbjct: 21817 TVTDLQAGEEYKFRVSAINGAGKGD---------SCEVTGTIKAVDRLTAPELDIDANFK 21867
Query: 727 SVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLP 782
+ A + + +++ + T + + LS D D ST T N
Sbjct: 21868 QTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADI-HTTDSFSTLTVENCNRNDA 21926
Query: 783 GRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----API 838
G KY + V S G +S+ + P P T V S + W P A I
Sbjct: 21927 G-KYTLTVENNS--GSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARI 21983
Query: 839 TGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898
Y + + S ++ T ++DL GV Y + AV E P + +
Sbjct: 21984 HHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPI 22043
Query: 899 TGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVN----LPGEH 950
T + PR L V+ + + W P+ S +TGY +++ + H
Sbjct: 22044 VATEQP---APPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGH 22100
Query: 951 GQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETD 1010
++L + E T Y F+V A + S+P A + + P
Sbjct: 22101 TKQLTFTVERLVEKT------EYEFRVKAKNDAGYSEPREAFSSVIIKEPQ--------- 22145
Query: 1011 STVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNV------GPSVSKYPLRNLQPASEYTV 1064
P A +TG + + G P +V P V+ + L ++ V
Sbjct: 22146 -------IEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVT-WKLEEMRLKETDRV 22197
Query: 1065 SLVAIKGN-----QESPKATG--VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIG--- 1114
S+ K ++S + F TL+ + + ++ T+V+ P P G
Sbjct: 22198 SITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSV-----TVVVIGRPGPVTGPIE 22252
Query: 1115 ----------FKLGVRPSQGGEAPREVTS------DSGS--------------IVVSGLT 1144
G P GG E+T+ +SG+ I V+ LT
Sbjct: 22253 VSSVSAESCVLSWG-EPKDGGGT--EITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLT 22309
Query: 1145 PGVEYVYTIQVL-RDGQER---DAPIV--NKVVTPLSP--PTNLHLEANPDTGVLTVSWE 1196
+EY + + R G + API+ + V P +P P H+ AN +++ WE
Sbjct: 22310 KYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSAN----AMSIRWE 22365
Query: 1197 RSTTPDITGYRITTTPTNGQQGNSL----EEVVHADQSSCTFDNLSPGLEYNVSVYTV-- 1250
G +I ++ N++ E V + + L GLEY Y +
Sbjct: 22366 EPYHDG--GSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNA 22423
Query: 1251 ----KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYS 1303
K + S PI V P T++ T+ + W+ P + +++
Sbjct: 22424 AGVSKASEASRPIMAQ--NPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERK 22481
Query: 1304 PVKNEEDVAELSIS---PSDNAVVLTNLLPGTEYVVSVSS------VYEQHEST-PLRGR 1353
PV D L + SDN +T L G Y V + + + EST P+ R
Sbjct: 22482 PVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCR 22541
Query: 1354 Q-----KTGLDSPTGIDFSDITANSFTVHWIA----PRATITGYRIRHHPEHFSGRPRED 1404
K LD+ D I A S V A P I + + +
Sbjct: 22542 DEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY 22601
Query: 1405 RVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRD---LEVVAATP 1461
+ I + + +Y +++ +G + +++ V D P L V T
Sbjct: 22602 TGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMV----KVLDSPGPCGKLTVSRVTQ 22657
Query: 1462 TSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT--ISGLKPGVDYT 1515
++W P + +Y + ET S + V G T + ++ L +Y
Sbjct: 22658 EKCTLAWSLPQEDGGAEITHYIVERRET---SRLNWVIVEGECPTLSYVVTRLIKNNEYI 22714
Query: 1516 ITVYAVTGRGDS-PASSKPISINYRTEIDKPSQM-QVTDVQDNSISVKWLPSSSP----V 1569
V AV G P S+PI I P + + I ++W S +
Sbjct: 22715 FRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEI 22774
Query: 1570 TGYRVTTTPKNGPGPTKT-KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628
+ Y V K T+ K T + + L +Y V A N +G S+P +
Sbjct: 22775 SNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASN 22834
Query: 1629 VTNIDRPK-------GLAFTDVDVDSIKIAWESPQGQVSRYRVTY-----SSPEDGIHEL 1676
+ P D SI +AW P V Y D + +
Sbjct: 22835 FISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRV 22894
Query: 1677 FPAPDGEEDTAELQGLRPGSEYTVSVVALH---------DDMESQPLIGTQSTAIPAPTD 1727
+ L+ G +Y+ V A++ E +P+ + + D
Sbjct: 22895 HTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADD 22954
Query: 1728 LKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTG---PMKEINLAPDSSSVVVSGLMV 1784
LK T S + V ++G V K G + I +S S+++ +
Sbjct: 22955 LKKTVTIRAGASLRLM---VSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKV- 23010
Query: 1785 ATKYEVSVYALKDTLTS--RPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT---- 1838
+Y+ Y ++ S + A +V + P +V + + ++TI+W T
Sbjct: 23011 -NRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGG 23069
Query: 1839 ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIY-----LYTLNDNARSS 1893
+ + V+ A + T K Y I+GL GT Y +Y + + +S
Sbjct: 23070 APVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETS 23129
Query: 1894 PVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVP 1949
V+ + + P+ L + T +++ ++W+ P +R+TGY+++ K G+ V
Sbjct: 23130 DAVLVSEVPL-VPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVV 23188
Query: 1950 RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPE 2009
+P V E T+T L G +Y + A SEP E VT+ +L
Sbjct: 23189 TLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEP-------RETVTAVTV--QDLRVLP 23239
Query: 2010 ILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPI 2069
+D+ + QKT V G ++L +P F R + T T
Sbjct: 23240 TIDLSTMPQKTIHV-----PAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHT 23294
Query: 2070 RHRPRPYPPNVGQEALSQTTISWAPFQDTSEYIISCHPV-GTDEEPLQFRV---PGTST 2124
+ V + + +TTI +DT EY + V GT E ++ + PG T
Sbjct: 23295 K---------VAKLTIRETTI-----RDTGEYTLELKNVTGTTSETIKVIILDKPGPPT 23339
Score = 84.3 bits (207), Expect = 1e-15
Identities = 258/1201 (21%), Positives = 430/1201 (35%), Gaps = 157/1201 (13%)
Query: 908 PSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS------RNTF 961
P L EVT K + W PP G ++D V RL + + T
Sbjct: 15060 PPEGPLAVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQK--RETSRLAWTNVASEVQVTK 15116
Query: 962 AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL------DAPTNLQFVNETDSTVLV 1015
+VT L G Y F+V AV+ +PL ++ + D P N + T +++V
Sbjct: 15117 LKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVV 15176
Query: 1016 RWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVS-----KYPLRNLQPASEYTVSLVAIK 1070
W P + + + RR + Q + + +Y + L EY ++A
Sbjct: 15177 CWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAEN 15236
Query: 1071 G-NQESPKATGVF-----TTLQPGSSIPPYNTEVTETT---IVITWTP------APRIGF 1115
+P T F T +PG PP N V +T+ I I W + G+
Sbjct: 15237 AAGISAPSPTSPFYKACDTVFKPG---PPGNPRVLDTSRSSISIAWNKPIYDGGSEITGY 15293
Query: 1116 KLGVRPSQGGEAPREVTSDSG----SIVVSGLTPGVEYVYTIQVLRD---GQERDAPIVN 1168
+ + + E + VT +G S ++GLT EY I + G+ P
Sbjct: 15294 MVEIALPEEDEW-QIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTP 15352
Query: 1169 KVVTPLSPPT-NLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
K + PP L + + R P I G G SL++
Sbjct: 15353 KAEDRMLPPEIELDADLRKVVTIRACCTLRLFVP-IKGRPAPEVKWARDHGESLDKASIE 15411
Query: 1228 DQSSCTFDNLSPGLEYNVSVY--TVKDDK--ESVPISDTIIPAVPPPTDLRFTNIGPDTM 1283
SS T + ++ Y TV++ +S ++ ++ PP DL+ + ++
Sbjct: 15412 STSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSV 15471
Query: 1284 RVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD---NAVVLTNLLPGTEYVVSVSS 1340
+TW PP +D + + Y K E S ++ + + L G Y V +
Sbjct: 15472 TLTW-DPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLA 15530
Query: 1341 VYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR----ATITGYRIRH 1392
E P + P I D+T NS ++ W P + I GY +
Sbjct: 15531 ENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEM 15590
Query: 1393 HPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPR 1452
+ V + T+T L G EY + A N E + +Q +V + +
Sbjct: 15591 QTKGSDKWATCATVKVTE--ATITGLIQGEEYSFRVSAQN---EKGISDPRQLSVPVIAK 15645
Query: 1453 DLEVVAA------TPTSLL---ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
DL + A T T L + D P + +T+ + N P+++ T ++ST
Sbjct: 15646 DLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKD--NVPLKQTTRVNAESTE 15703
Query: 1504 TISGL--KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ----MQVTDVQDNS 1557
S L K + Y V + + + +++ +DKP +++ +V +S
Sbjct: 15704 NNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNV---IVLDKPGPPTGPVKMDEVTADS 15760
Query: 1558 ISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG--LQPTVEYVVS 1611
I++ W P S + Y V K T + TI+ L+ EY
Sbjct: 15761 ITLSWGPPKYDGGSSINNYIVE---KRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFR 15817
Query: 1612 VYAQNPSGES-----QPLVQTAVTNIDRPKGLAFTDVDV-DSIKIAWESPQGQVSRYRVT 1665
+ A+N G+S +P V + P G + DS+++ W P +
Sbjct: 15818 IAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIG 15877
Query: 1666 YSSPEDGIHELF-------PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ 1718
Y + + P P + T GL G EY V A + +P ++
Sbjct: 15878 YHLERKERNSILWVKLNKTPIPQTKFKTT---GLEEGVEYEFRVSAENIVGIGKPSKVSE 15934
Query: 1719 STAIPAPTDL----KFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINL 1770
P D + VT S++ QW P ++TGY V + MK
Sbjct: 15935 CYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFT 15994
Query: 1771 APDSSSVVVSGLMVATKYEVSVYALKDT-LTSRPAQ--GVVTTLENVSPPRRARVTDATE 1827
+ V+GL+ +YE V A + S P++ G +T + V PPR + +
Sbjct: 15995 NIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKD 16054
Query: 1828 TTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ-PGTDYKIYLYTL 1886
T + + + F+VDA P + IK D L+ TD+ L ++
Sbjct: 16055 TIVVHAGES-------FKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSL-SV 16106
Query: 1887 NDNAR--SSPVVIDASTAIDAPS---NLRFL-------------ATTPNSLLVSWQPPR- 1927
D R S ++ A S N++ L T ++W+PP
Sbjct: 16107 KDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQ 16166
Query: 1928 ---ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
+ I YI++ + VV +T L G EYT ++A+ EP
Sbjct: 16167 DGGSDIINYIVERRETSRLVWTVVDA-NVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEP 16225
Query: 1985 L 1985
L
Sbjct: 16226 L 16226
Score = 83.6 bits (205), Expect = 2e-15
Identities = 268/1312 (20%), Positives = 473/1312 (36%), Gaps = 176/1312 (13%)
Query: 812 DAPPDPT----VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN 863
D P PT + + + S+ ++W P+ + +T Y ++ + TE++
Sbjct: 20071 DRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVART 20130
Query: 864 SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV-EVTDVK 922
+ + L G +Y I A EN+ I T P P +V VT
Sbjct: 20131 MMKVMKLTTGEEYQFRIKA--ENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRES 20188
Query: 923 VTIMWTPPES----AVTGYRVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
+T+ W P S AV GY +++ N + + +L I R T +VT +S G+ Y F+V
Sbjct: 20189 ITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVI-RTTHFKVTTISAGLIYEFRV 20247
Query: 978 FAVSHGRESKPL-TAQQTTKLDA---PTNLQFVNETDSTVLVRWTPPR----AQITGYRL 1029
+A + KP ++ +DA P N++ + + ++V + W P ++ITGY
Sbjct: 20248 YAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYI- 20306
Query: 1030 TVGLTRRGQP-----RQYNVGPSVSKYPLRNLQPASEYTVSLVA--IKGNQESP-KATGV 1081
+ RR P + + +++ + L S+Y + A G+ +P + G
Sbjct: 20307 ---VERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGP 20363
Query: 1082 FTTLQ----PGSSIPPYNTEVTE----TTIV----ITWTPAPRI-GFKLGVRPSQGGEAP 1128
T + P +P TEV + T++ I+ PAP I +K
Sbjct: 20364 ITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVC 20423
Query: 1129 REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
E T+D SI++ Y +++ A I +++ PP
Sbjct: 20424 VENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTA 20483
Query: 1189 GVLTVSWERSTTPD----ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
+T+ W R D IT Y + T+ + + E H ++ T + G EY
Sbjct: 20484 EKITLLW-RPPADDGGAKITHYIVEKRETSRVVWSMVSE--HLEECIITTTKIIKGNEYI 20540
Query: 1245 VSVYTVKDDKESVPI-SDTIIP-----AVPPPTDLRFTNIGPDTMRVTWAPP---PSIDL 1295
V V P+ SD+++ PP T I ++M V W+ P D+
Sbjct: 20541 FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDI 20600
Query: 1296 TNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY---VVSVSSVYEQHESTPLRG 1352
+ + + K+ L + D +T L ++Y V +V++ + S P
Sbjct: 20601 SGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEF 20660
Query: 1353 RQKTGLDSPTG----IDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPRED 1404
+ P G I +D T +S T+ W P + +TGY + E G E
Sbjct: 20661 YKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVV----EIRQGEEEEW 20716
Query: 1405 RVPHSRNSITLT-----NLTPGTEYVVSIVALN-GREESPLLIGQQSTVSDVPR----DL 1454
++ + T NL PG Y + A+N + P+ + + D+ DL
Sbjct: 20717 TTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDL 20776
Query: 1455 EVVAATPTSLLISWDA-----------PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
+V T D P VT R G S S S
Sbjct: 20777 DVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYS----IENTDSSSLL 20832
Query: 1504 TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISV 1560
TI + + G G+ +S+ + + +D P+ ++QV V ++++
Sbjct: 20833 TIPQVTRNDTGKYILTIENGVGEPKSSTVSVKV-----LDTPAACQKLQVKHVSRGTVTL 20887
Query: 1561 KWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGP-DQTEMTIEGLQPTVEYVVSVYAQ 1615
W P SP+ Y + ++ T + + T + L + V A+
Sbjct: 20888 LWDPPLIDGGSPIINYVI--EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAE 20945
Query: 1616 NPSGESQPLVQT---AVTNIDRP-KGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPED 1671
N G +P T + P + L+ D S+ ++W P Y
Sbjct: 20946 NEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERK 21005
Query: 1672 GIHELFPAPDGEEDTAELQ--GLRPGSEYTVSVVALHDDMESQPL-IGTQSTAIPAPTDL 1728
G E + G T E++ L+ S V A ++ S P+ IG P +
Sbjct: 21006 GKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIG--------PITV 21057
Query: 1729 KFTQVTP-TSLSAQWTPPNVQLT---GYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMV 1784
K +TP LS P Q+T G+ V + K P I+ D + S +
Sbjct: 21058 KELIITPEVDLS---DIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVR 21114
Query: 1785 ATKYEVSV-YALKDTLTSRPAQ------------GVVTTLENVSPPRR----ARVTDATE 1827
+K E + ++K+ + V T+ + PP + R +
Sbjct: 21115 FSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKA 21174
Query: 1828 TTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVR-SYTITGLQPGTDYKIY 1882
++ +SW + IT + ++ QT + R ++ + L +Y+
Sbjct: 21175 DSVILSWDVPEDNGGGEITCYSIEK-RETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFR 21233
Query: 1883 LYTLNDNARSSPVVIDASTA------IDAPSNLRFLATTPNSLLVSWQPP----RARITG 1932
+ N S P+V A P T + + ++W P + +TG
Sbjct: 21234 VRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTG 21293
Query: 1933 YIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
+ ++ ++ S + V E TGL G +Y V A + S P
Sbjct: 21294 FHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSP 21345
Score = 83.2 bits (204), Expect = 3e-15
Identities = 293/1378 (21%), Positives = 491/1378 (35%), Gaps = 236/1378 (17%)
Query: 811 PDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVT 866
P P + V + S + W P + IT Y I + S + E N+
Sbjct: 9001 PSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVI---DKRDASRKKAEWEEVTNTAV 9057
Query: 867 -----LSDLQPGVQYNITI-----YAVEENQESTPVVIQQ--ETTGTPRSDTVPSPRDLQ 914
+ L P QY + Y + + +S VVIQ G P V
Sbjct: 9058 EKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKV------- 9110
Query: 915 FVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLP-GEHGQRLPISR----NTFAEVT 965
+ T + + WTPP S +TGY ++ P R PI++ V
Sbjct: 9111 -LARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVP 9169
Query: 966 GLSPGVTYYFKVFAVSH---GRESKP----LTAQQTTKLDAPTNLQFVNETDSTVLVRWT 1018
L GV Y F+ A++ G S+P + P+ + ++T S++ + W
Sbjct: 9170 RLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWK 9229
Query: 1019 PPR----AQITGYRLTV---GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIK- 1070
PP + I GY + + G T + + + + + + NL+ +Y + A+
Sbjct: 9230 PPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVNE 9289
Query: 1071 -GNQESPKATG------------VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKL 1117
G E TG VF + + VI P P+ ++
Sbjct: 9290 AGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEF 9349
Query: 1118 GVRPSQG---------GEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVN 1168
+ + +A E +S I++ Y+I ++ A
Sbjct: 9350 DGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRV 9409
Query: 1169 KVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD------ITGYRITTTPTNGQQGNSLE 1222
KV+ PP +L + ++ G +SW+ PD I GY I +G+
Sbjct: 9410 KVMDVPGPPKDLKV-SDITRGSCRLSWKM---PDDDGGDRIKGYVIEKRTIDGKAWTK-- 9463
Query: 1223 EVVHADQSSCTF--DNLSPGLEYNVSV-----YTVKDDKESVPISDTIIPAVPP--PTDL 1273
V+ D S TF +L +Y V + + E++ + P PP P L
Sbjct: 9464 --VNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKL 9521
Query: 1274 RFTNIGPDTMRVTWAPPPS---IDLTNFLVR---YSPVK---------NEEDVAELSISP 1318
+ I +T+ ++W PP + +T+++V + P N+ DV EL +
Sbjct: 9522 KIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTV 9581
Query: 1319 SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL---DSPTGIDFSDI--TANS 1373
D L+ G EY V +V S P D P ID +
Sbjct: 9582 ED-------LVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEG 9634
Query: 1374 FTVHWIA-----PRATITGYRIRH----------HPEHFSGRPREDR----VPHSRNSIT 1414
V+ +A P T+T ++ + H + +D +P SR S T
Sbjct: 9635 TNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDT 9694
Query: 1415 LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP--- 1471
Y ++ V G + + ++ + + + +SW P
Sbjct: 9695 GL-------YTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDD 9747
Query: 1472 -AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG-DSPA 1529
+ Y I E + V + P + T TI L G +Y + A G P
Sbjct: 9748 GGSKITNYVIEKREANRKTWVHVSSEP-KECTYTIPKLLEGHEYVFRIMAQNKYGIGEPL 9806
Query: 1530 SSKPISI-NYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVT---TTPKN- 1580
S+P + N + P + V+ V NS++V W SPVTGY + TT K
Sbjct: 9807 DSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRW 9866
Query: 1581 ---GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG---ESQPLVQTAVTNIDR 1634
P K T G + GL +Y VYA N +G S P +
Sbjct: 9867 KRVNRDPIKAMTLG---VSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIA 9923
Query: 1635 PKGLAF---TDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTA 1687
P G F TD S + W P +V+ Y V Y E+G E D E
Sbjct: 9924 PPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYK--EEGKEEWEKGKDKEVRGT 9981
Query: 1688 EL--QGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPT-SLSAQWTP 1744
+L GL+ G+ Y V A++ +P G + I ++K V+P L A
Sbjct: 9982 KLVVTGLKEGAFYKFRVRAVNIAGIGEP--GEVTDVI----EMKDRLVSPDLQLDASVRD 10035
Query: 1745 PNVQLTGYRVRVT-------PKEKTGPMKEINLAPDSS--SVVVSGLMVATKYEVS---V 1792
V G +R+ P T M E L +++ + +S MV + S V
Sbjct: 10036 RIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGV 10095
Query: 1793 YAL--KDTLTSRPAQGVVTTLENVSPPRRARVT-DATETTITISWRTKTET----ITGFQ 1845
Y+L K+ R +V L+ P + + T + ++W + + IT +
Sbjct: 10096 YSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYV 10155
Query: 1846 VDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND-------NARSSPVV 1896
++ ++ + TP+ T+ ++ T+ GL G Y + N + V+
Sbjct: 10156 IEKRESDRRAWTPVTYTVTR--QNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVI 10213
Query: 1897 IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPR 1952
+ T + P +L T N++ ++W PP+ + I Y+++ G+ V
Sbjct: 10214 REPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDN 10273
Query: 1953 PGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVT----LPHPNLH 2006
+ T+ GL+ G Y V A+ ++G+ K + +T L P LH
Sbjct: 10274 LLSRKYTVKGLKEGDTYEYRVSAVN-------IVGQGKPSFCTKPITCKDELAPPTLH 10324
Score = 82.0 bits (201), Expect = 6e-15
Identities = 266/1310 (20%), Positives = 442/1310 (33%), Gaps = 219/1310 (16%)
Query: 731 ITASSFVVSWVSASDTVSGFRVEYELSE-EGDEPQYLDLPSTAT--SVNIPDLLPGRKYI 787
++A +SW D Y + + E + ++ + S + IP LL G +Y+
Sbjct: 9732 VSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYV 9791
Query: 788 V-----NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----API 838
N Y I E + + + + P AP PTV V S+ V W P+ +P+
Sbjct: 9792 FRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPV 9851
Query: 839 TGYRIVYSPSVEGSSTELNLPETANSVTL------SDLQPGVQYNITIYAVEENQESTPV 892
TGY + + +N + ++TL + L G Y +YA+ P
Sbjct: 9852 TGYWLEMKDTTSKRWKRVN-RDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVG-PA 9909
Query: 893 VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
+ + P P + + T + W+PP S VTGY V+
Sbjct: 9910 SLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEE 9969
Query: 949 EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGR-----------ESKPLTAQQTTKL 997
+ R T VTGL G Y F+V AV+ E K +L
Sbjct: 9970 WEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQL 10029
Query: 998 DAPTNLQFVNETDSTV----LVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSV--SKY 1051
DA + V + V PP +T + R P++ + + S
Sbjct: 10030 DASVRDRIVVHAGGVIRIIAYVSGKPPPT------VTWNMNERTLPQEATIETTAISSSM 10083
Query: 1052 PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT-EVTETTIVITWTP- 1109
++N Q + + SL+A E K V PG P+ +T + +TW
Sbjct: 10084 VIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSP 10143
Query: 1110 -----APRIGFKLGVRPS-QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD----- 1158
+P + + R S + P T + V GL G Y + I
Sbjct: 10144 EDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGP 10203
Query: 1159 -GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTN 1214
+ +A ++ + +T P +L ++ +T++W + +I Y + +
Sbjct: 10204 FVETSEALVIREPITVPERPEDLEVK-EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIG 10262
Query: 1215 GQQGNSLEEVVHADQSSCTFDNLSPG--LEYNVSVYTV----KDDKESVPISDTIIPAVP 1268
++ + + + T L G EY VS + K + PI T +
Sbjct: 10263 TEKFHKVTN-DNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPI--TCKDELA 10319
Query: 1269 PPT---------DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSI 1316
PPT +R T R + P P + S K+E DV E I
Sbjct: 10320 PPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKV---------SWFKDEADVLEDDRTHI 10370
Query: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP----TGIDFSDITAN 1372
+ + L + V E + Q +D P + F ++T +
Sbjct: 10371 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKD 10430
Query: 1373 SFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP----HSRNSITLTNLTPGTEYVVSI 1428
+ W P G +I ++ ++ +P ++ + ++ L G +Y+ I
Sbjct: 10431 YMVISW-KPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRI 10489
Query: 1429 VALNGREESPLLIG------QQSTVSDVPRDLEVVAATPTSLLISWDAP----------- 1471
A N S L+ + V D P V T S L++W+ P
Sbjct: 10490 HAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYI 10549
Query: 1472 -----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT--GR 1524
++ R+ R+T P +F VP L G Y V A G
Sbjct: 10550 LEKRETMSKRWARVTKDPI---HPYTKFRVP---------DLLEGCQYEFRVSAENEIGI 10597
Query: 1525 GDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRVTTT 1577
GD SKP+ + I KPS + D NS+ + W P S + GY +
Sbjct: 10598 GDPSPPSKPVFA--KDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGY-IVEY 10654
Query: 1578 PKNGPGPTKTKTAGPD---QTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LVQT 1627
K G + P+ +T+ + GL+ Y V A N +GES P LV+
Sbjct: 10655 QKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKD 10714
Query: 1628 AV--------TNIDRPKGLAFTDV--------DVDSIKIAWESPQGQVSRYRVTYSSPED 1671
+ N+ R + + D V K+ W+ +P
Sbjct: 10715 RLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVG 10774
Query: 1672 GIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFT 1731
E+ A + L P TVSV L D P DL+ +
Sbjct: 10775 SKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG------------PPRDLEVS 10822
Query: 1732 QVTPTSLSAQWTPP----NVQLTGYRVR-------------VTPKEKTGPMKEINLAPDS 1774
++ S W P +T Y V T K+K+ K +N
Sbjct: 10823 EIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLN----E 10878
Query: 1775 SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISW 1834
+ + + +Y + T +P + + L PP+ D +T +++ W
Sbjct: 10879 GNQYLFRVAAENQYGRGPF----VETPKPIK-ALDPLHPPGPPKDLHHVDVDKTEVSLVW 10933
Query: 1835 ----RTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYK 1880
R ITG+ V+ Q I+ ++ +TGLQ G Y+
Sbjct: 10934 NKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLEC-VVTGLQQGKTYR 10982
Score = 80.9 bits (198), Expect = 1e-14
Identities = 248/1194 (20%), Positives = 435/1194 (36%), Gaps = 142/1194 (11%)
Query: 908 PSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE 963
P +Q VT K ++ W+PP S ++ Y V+ + + N+ +
Sbjct: 17224 PPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSL-K 17282
Query: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA------PTNLQFVNETDSTVLVRW 1017
VT L G Y F++ AV+ +PL + + P +L+ N ++ V W
Sbjct: 17283 VTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCW 17342
Query: 1018 TPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQ---------PASEYTVSLVA 1068
P + G +G + R +K + +L+ E+ VS
Sbjct: 17343 NRPDSD--GGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAEN 17400
Query: 1069 IKGNQESPKATGVFTTLQPGSSI-PPYNTEVTETT---IVITWTP------APRIGFKLG 1118
G E AT + P PP N + +TT I + W + +G+ +
Sbjct: 17401 AAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVE 17460
Query: 1119 VRPSQGGEAPREVTSDSGSIV----VSGLTPGVEYVYTIQVLRD---GQERDAPIVNKVV 1171
+ + E + VT +G V +S LT EY + L G+ P K
Sbjct: 17461 ICKADEEEW-QIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPE 17519
Query: 1172 TPLSPPTNLHLEANPDTGVLT---------VSWERSTTPDITGYRITTTPTNGQQGNSLE 1222
L P L L++ G++ + ++ TP+IT R T+ Q +E
Sbjct: 17520 DKLEAP-ELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQ---IE 17575
Query: 1223 EVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDT 1282
+ V+ Q S + + +Y + + K + ++ ++ PP +L + D+
Sbjct: 17576 KGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAF-VTVKVLDTPGPPQNLAVKEVRKDS 17634
Query: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEED---VAELSISPSDNAVVLTNLLPGTEYVVSVS 1339
+ W PP ID + Y K E A +S S + + NL G Y V
Sbjct: 17635 AFLVWEPP-IIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVM 17693
Query: 1340 SVYEQHESTPLR---GRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIR 1391
+ E P+ + SP G + +D++ S ++ W P + + GY +
Sbjct: 17694 AENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE 17753
Query: 1392 HHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSIVALNGREES-PLLIGQQSTVSD 1449
P+ G + V S+ + +T L+ G EY + A N + +S P ++G D
Sbjct: 17754 MQPK---GTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKD 17810
Query: 1450 VPRDLEVVAATPTSLL-----ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT 1504
+ + T + + + P + I++ + G P+++ T + TAT
Sbjct: 17811 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDG--EPLKQTTRVNVEETAT 17868
Query: 1505 --ISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVK 1561
+ +K G Y VT + +++ +S+ + P ++ +V + + +
Sbjct: 17869 STVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVIS 17928
Query: 1562 WLPSS----SPVTGYRV-----TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV 1612
W P + ++ Y V TTT + T +T + I L+ EY +
Sbjct: 17929 WEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTT------IKITKLKTGTEYQFRI 17982
Query: 1613 YAQNPSGESQPLVQTAVT-----NIDRPKGLAF-TDVDVDSIKIAWESPQGQVSRYRVTY 1666
+A+N G+S PL AV P G F T + D + + W P + Y
Sbjct: 17983 FAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGY 18042
Query: 1667 SSPEDGIHELF-------PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQS 1719
+ + + P D + T GL G EY V A + +P ++
Sbjct: 18043 HLEQKEKNSILWVKLNKTPIQDTKFKTT---GLDEGLEYEFKVSAENIVGIGKPSKVSEC 18099
Query: 1720 TAIPAPTD----LKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLA 1771
P D + +T +++ +W P ++TGY V MK
Sbjct: 18100 FVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTN 18159
Query: 1772 PDSSSVVVSGLMVATKYEVSVYALKDTLT-SRP--AQGVVTTLENVSPPRRAR------- 1821
+ VSGL+ +YE V A S P + G +T + + P +
Sbjct: 18160 VLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDV 18219
Query: 1822 -VTDATET-TITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ-PGTD 1878
V A ET + R K + D +T + IK ++ T+ TD
Sbjct: 18220 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELE-ETAARMEIKSTIQKTTLVVKDCIRTD 18278
Query: 1879 YKIYLYTLND--NARSSPVVIDASTAIDAPSN-LRFLATTPNSLLVSWQPP----RARIT 1931
Y+ L++ +S P+ + P L+ T ++W PP A I+
Sbjct: 18279 GGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANIS 18338
Query: 1932 GYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 1985
YII+ + V + +T L PG EY V+A+ EPL
Sbjct: 18339 HYIIEKRETSRLSWTQVSTEVQAL-NYKVTKLLPGNEYIFRVMAVNKYGIGEPL 18391
Score = 78.6 bits (192), Expect = 7e-14
Identities = 278/1375 (20%), Positives = 475/1375 (34%), Gaps = 200/1375 (14%)
Query: 797 GEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGS 852
G +++ + P P D V ++ S + W P + IT Y +
Sbjct: 10799 GSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ 10858
Query: 853 STELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRD 912
+ L+ S L G QY + A + V + P+D
Sbjct: 10859 WSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKD 10918
Query: 913 LQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE----V 964
L V+V +V+++W P+ S +TGY V+ E G + I T V
Sbjct: 10919 LHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEY------QEEGTQDWIKFKTVTNLECVV 10972
Query: 965 TGLSPGVTYYFKVFA---VSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
TGL G TY F+V A V G + + KL P+ V + V+ T R
Sbjct: 10973 TGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVR 11032
Query: 1022 --AQITGYRL-TVGLTRRGQPRQYNVGPSV------SKYPLRNL--QPASEYTVSLVAIK 1070
A I G + T T G + + +V S ++N + EY +++
Sbjct: 11033 FPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV---- 11088
Query: 1071 GNQESPKATGVFTTLQ--PGSSIPPYNT-EVTETTIVITWTPAPRIGFKLGVRPSQGGEA 1127
N K V T+ PG P N +VT + I+W P P G +
Sbjct: 11089 SNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQP-----------PKDDGGS 11137
Query: 1128 P--------REVTSDSGSIVVSG----------LTPGVEYVYTIQV---LRDGQERDA-P 1165
P ++ D+ +V SG L G EYV+ ++ + G D+ P
Sbjct: 11138 PVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTP 11197
Query: 1166 IVNK-VVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSL 1221
V K +P SPP + + TVSW + ITGY + G+
Sbjct: 11198 TVAKHKFSPPSPPGK-PVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVN 11256
Query: 1222 EEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVP-----PPTDLRFT 1276
+ + + T E+ V + + P SD I P PP + +
Sbjct: 11257 KTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLK 11316
Query: 1277 NIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDN-----AVVLTNLLPG 1331
+ +T + W P S D + ++ Y + A+ + D A + L+ G
Sbjct: 11317 DKSRETADLVWTKPLS-DGGSPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEG 11375
Query: 1332 TEYVVSVSSVYEQHESTPLRGRQKT---GLDSPTGIDFSDITANSFTVHWIAPRATITGY 1388
EY + + E P + + P ++ D+T + I
Sbjct: 11376 NEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVEL-DVTCRDVITVRVGQTIRILA- 11433
Query: 1389 RIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE-------------YVVSIVALNGRE 1435
R++ PE +E +V + L P E Y++S +G
Sbjct: 11434 RVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHA 11493
Query: 1436 ESPLLIGQQSTVSDVP---RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQ 1492
+ ++ V D P ++L+V T + ISW+ P + G + + +
Sbjct: 11494 QGSAIVN----VLDRPGPCQNLKVTNVTKENCTISWENP--------LDNGGSEITNFIV 11541
Query: 1493 EFTVPGSKSTATISG----------LKPGVDYTITVYAVTGRGDSPASSKPISINYRTEI 1542
E+ P K + ++ L +Y V A G P I I
Sbjct: 11542 EYRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPI 11601
Query: 1543 DKPSQ---MQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 1595
D+P + + + D + +KW SP Y V K + +T
Sbjct: 11602 DRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKET 11661
Query: 1596 EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSI------- 1648
++ Y V +N GES V+T + D+ + +
Sbjct: 11662 HYMVDRCVENQIYEFRVQTKNEGGESD-WVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGD 11720
Query: 1649 KIAWESPQGQVSRYRVTYSSPEDGIHELFPAP----DGEEDTAELQGLRP----GSEYTV 1700
I E+ V ++ +D +L +P D D+++ + G +Y V
Sbjct: 11721 TIRLEAGVRGKPFPEVAWTKDKDAT-DLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVV 11779
Query: 1701 SVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKE 1760
+ + + P +LK V+ + W PP G ++ E
Sbjct: 11780 TATNTAGSFVAYATVNVLDKPGPV-RNLKIVDVSSDRCTVCWDPPEDD-GGCEIQNYILE 11837
Query: 1761 KTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV------ 1814
K K + + S++V+ G V E + Y + ++ G T + V
Sbjct: 11838 KC-ETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKY 11896
Query: 1815 ---SPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQ--TPIQRTIKPDV 1865
P VT ++ +T+ W ++ITG+ ++ + P+ ++ P+
Sbjct: 11897 DKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPE- 11955
Query: 1866 RSYTITGLQPGTDYKIYLYTLND------NARSSPVVI-DASTAIDAPSNLRFLATTPNS 1918
R + L P +Y+ + N+ + S PVV D P+N R + TT +S
Sbjct: 11956 RRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHS 12015
Query: 1919 LLVSWQPP----RARITGYIIKYEK--PGSPPREVVPRPRPGV----TEATITGLEPGTE 1968
+ + W P A I GY+++ + P E R E T+T L+ E
Sbjct: 12016 ITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQE 12075
Query: 1969 YTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFV 2023
Y V A NQ +G + EL + + P L PEI D+ ++++K V
Sbjct: 12076 YEFRVCA--QNQ-----VGIGRPAELKEAIK-PKEILEPPEI-DLDASMRKLVIV 12121
Score = 78.6 bits (192), Expect = 7e-14
Identities = 169/767 (22%), Positives = 275/767 (35%), Gaps = 120/767 (15%)
Query: 601 PLQTYPSSSGPVEVFITETPSQPN-------SHPIQWNAPQ---PSHISKYILRWRPKNS 650
P +T P VF+ PS+P + I W P + I+ Y + ++ +
Sbjct: 19571 PSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDD 19630
Query: 651 VGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT 710
WK + YTI GL G Y ++ S+ + G + + +S P +
Sbjct: 19631 TD-WKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASD-------PSDSSDPQIAKE 19682
Query: 711 VTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVS--GFRVEYELSEEGDEP----Q 764
E PL +E+ + V + S + TV G V L + D
Sbjct: 19683 REEE-----PLFDID---SEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA 19734
Query: 765 YLDLPSTATSVNIPDLL--PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV 822
Y+D + TS+ I + KY + + + +L++ T P P + TV V
Sbjct: 19735 YVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGP--PTNITVQDV 19792
Query: 823 DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNI 878
S V+ W P+ AP+ Y I + + + + S +++LQ G Y
Sbjct: 19793 TKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYF 19852
Query: 879 TIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAV 934
+ E P ++ G ++ P L ++ V++ W PE S +
Sbjct: 19853 RVSGENEFGVGIPAETKE---GVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRI 19909
Query: 935 TGYRVDVIPVNLPGEHGQR----LPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-- 988
Y V+ + E GQ+ ++++T V+GL Y+F+VFA + S P
Sbjct: 19910 VHYVVEAL------EKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRE 19963
Query: 989 -LTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
L + P + N TV VR G L V + G+P V S
Sbjct: 19964 LLLPVLIKEQLEPPEIDMKNFPSHTVYVR--------AGSNLKVDIPISGKPLP-KVTLS 20014
Query: 1048 VSKYPLR-NLQPASEYTV---------SLVAIKGNQESPKATGVFTTL---------QPG 1088
PL+ ++ +E T S+ A G E A TT +PG
Sbjct: 20015 RDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPG 20074
Query: 1089 SSI-PPYNTEVTETTIVITWTPAPRIG-------FKLGVRPSQGGEAPREVTSDSGSIVV 1140
P +++TE ++ + W P G L S T + V
Sbjct: 20075 PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKV 20134
Query: 1141 SGLTPGVEYVYTIQV-----LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
LT G EY + I+ + D + V T PP+ + N +TV W
Sbjct: 20135 MKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWV-TNVTRESITVGW 20193
Query: 1196 ERSTT---PDITGYRITTTPTNG---QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249
+ + GY + N Q+ N L V+ T +S GL Y VY
Sbjct: 20194 HEPVSNGGSAVVGYHLEMKDRNSILWQKANKL--VIRTTHFKVT--TISAGLIYEFRVYA 20249
Query: 1250 V------KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP 1290
K S P+ I A PP ++R T+I +++ ++W P
Sbjct: 20250 ENAAGVGKPSHPSEPV--LAIDACEPPRNVRITDISKNSVSLSWQQP 20294
Score = 66.2 bits (160), Expect = 4e-10
Identities = 301/1561 (19%), Positives = 557/1561 (35%), Gaps = 218/1561 (13%)
Query: 628 IQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W+AP S ++ + + + +NS+ K T P Y GL G+ Y+ ++ +
Sbjct: 21278 LTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAE 21337
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
G S+P + T +P P + ++T + + W
Sbjct: 21338 NSAG-------------LSSPSDPSKFTLAVSPVDP--PGTPDYIDVTRETITLKWNPPL 21382
Query: 745 DTVSGFRVEYELSEEGDEPQYLDLPSTATS---VNIPDLLPGRKYIVNVYQ------ISE 795
V Y + + +++ T S + L PG +Y + IS
Sbjct: 21383 RDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISP 21442
Query: 796 DGEQSLILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWS--RPQAPITGYRIV----YS 846
+ S I+ T P P V+ + D I+ R +A + G + +
Sbjct: 21443 PSQSSGIIMTRDENVP-----PIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFK 21497
Query: 847 PSVE-GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES--TPVVIQQETTGTPR 903
VE + + + S +L ++ + + +Y VE S I+ + TP
Sbjct: 21498 DGVEIEKRMNMEITDVLGSTSLF-VRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPG 21556
Query: 904 SDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVNLPGEHGQRLPISRN 959
P ++F +T K+T+ W P + +T Y ++ +
Sbjct: 21557 KVVGP----IRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQ 21612
Query: 960 TFAEVTGLSPGVTYYFKVFAVSH---GR--ESKPLTAQ-QTTKLDAPTNLQFVNETDSTV 1013
++ + L G Y F+V AV+ GR +S P+ AQ Q T DAP + N T +++
Sbjct: 21613 SYTAIK-LINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSI 21671
Query: 1014 LVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN-------LQPASEYTVSL 1066
+ W P + G + + R + + +SK P+ L +EY +
Sbjct: 21672 TLTWARPESD-GGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHV 21730
Query: 1067 VAIKGNQESPKATGVFTTLQ-------PGSSIPPYNTEVTETTIVITWTPA------PRI 1113
+A P A+G+ ++ PG T+ ++TT+ + W+ I
Sbjct: 21731 MAENAAGVGP-ASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEII 21789
Query: 1114 GFKLGVRPSQGGEAPREVTSDS---GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
G+ + + + G+ +V +++ V+ L G EY + + + + D+ V
Sbjct: 21790 GYIIEMCKADLGDW-HKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGT 21848
Query: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT----NGQQGNSLEEVVH 1226
+ + T L+ + + V ++ Y+ TPT SL +H
Sbjct: 21849 IKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIH 21908
Query: 1227 ADQSSCTFD----NLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDT 1282
S T N + +Y ++V K S+ + ++ PP + F ++ +
Sbjct: 21909 TTDSFSTLTVENCNRNDAGKYTLTVENNSGSK-SITFTVKVLDTPGPPGPITFKDVTRGS 21967
Query: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLPGTEYVVSVS 1339
+ W P +D + Y K E +S + + +L G Y VS
Sbjct: 21968 ATLMW-DAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVS 22026
Query: 1340 SVYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR----ATITGYRIR 1391
+V E P + P +D D + +S + W+ P + ITGY +
Sbjct: 22027 AVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLE 22086
Query: 1392 HHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV 1450
+ G H++ + T+ L TEY + A N S S +
Sbjct: 22087 MRQK---GSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKE 22143
Query: 1451 PR-----DLEVV--------AATPTSL---LISWDAPAVTVRYYRITYGETGGNSPVQEF 1494
P+ DL + A +P ++ + AP VT + + ET S
Sbjct: 22144 PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVS----I 22199
Query: 1495 TVPGSKSTATISGLKPGVD--YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQM---- 1548
T ++T T+ G Y +T+ ++ A K S+ I +P +
Sbjct: 22200 TTTKDRTTLTVKDSMRGDSGRYFLTL-------ENTAGVKTFSVTV-VVIGRPGPVTGPI 22251
Query: 1549 QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
+V+ V S + W + +T Y + ++G + + +T++ + L
Sbjct: 22252 EVSSVSAESCVLSWGEPKDGGGTEITNY-IVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 22310
Query: 1605 TVEYVVSVYAQNPSGESQPLVQTAV------TNIDRPKGLAFTDVDVDSIKIAWESPQGQ 1658
+EY V ++N G S+PL + P V +++ I WE P
Sbjct: 22311 YMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHD 22370
Query: 1659 VSRYRVTYSSPEDGIHELFPAPDGE----EDTAELQGLRPGSEYTVSVVALH------DD 1708
+ Y + + + + + E ++ GL G EY AL+
Sbjct: 22371 GGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKAS 22430
Query: 1709 MESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGP 1764
S+P++ + AP + T VT +++S W+ P ++ GY + P + G
Sbjct: 22431 EASRPIMA--QNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGD 22488
Query: 1765 ---MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT-LTSRPAQ--GVVTTLENVSPPR 1818
+K + V+ L YE V A + S+ ++ G VT + +PP+
Sbjct: 22489 GRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPK 22548
Query: 1819 RARVTDATETTITISWRTKTETITGFQVDAVP------ANGQTPIQRTIKPDV-----RS 1867
DA ++ R ++ + V P G + K + R+
Sbjct: 22549 AE--LDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRA 22606
Query: 1868 YTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP---SNLRFLATTPNSLLVSWQ 1924
+ +D Y T+ NA + V +D+P L T ++W
Sbjct: 22607 TAVIKFCDRSDSGKYTLTVK-NASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWS 22665
Query: 1925 PPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKN-- 1978
P+ A IT YI++ + +V P ++ +T L EY V A+
Sbjct: 22666 LPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLS-YVVTRLIKNNEYIFRVRAVNKYG 22724
Query: 1979 ---NQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFV--THPGYDTGNG 2033
+SEP++ R T+P P P I + T ++ + T P D GN
Sbjct: 22725 PGVPVESEPIVARNS-------FTIPSP----PGIPEEVGTGKEHIIIQWTKPESDGGNE 22773
Query: 2034 I 2034
I
Sbjct: 22774 I 22774
Score = 60.8 bits (146), Expect = 1e-08
Identities = 178/828 (21%), Positives = 291/828 (35%), Gaps = 149/828 (17%)
Query: 1263 IIPAVPPPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPS 1319
+I P +L T + + W P + + ++V +K + V + S
Sbjct: 6589 VIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAES 6648
Query: 1320 DNAVVLTNLLPGTEYVVSVSS-----VYEQHES-TPLRGRQKTGLDSPT-GIDFSDITAN 1372
V G EY+ VS+ E E+ P+ R K + P + +D+
Sbjct: 6649 CEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRF 6708
Query: 1373 SFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSI 1428
++ W P A IT Y I + V S T+T++ G EY +
Sbjct: 6709 GVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRV 6768
Query: 1429 VALNGREESPLLIGQQSTVSDV------------PRDLEVVAATPTSLLISWDAP----A 1472
R ++ + +G+ S + P +L T +S+ + W+ P
Sbjct: 6769 -----RAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGG 6823
Query: 1473 VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSK 1532
+ Y I E G ++ ++ + T ++GL+ G Y V A G S S
Sbjct: 6824 SPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEI 6883
Query: 1533 PISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSS--PVTGYRVTTTPKNGPGPTKTKTA 1590
+ +P+ M ++ +D + P + P TGY P PT T
Sbjct: 6884 LGPLTADDAFVEPT-MDLSAFKDGLEVIVPNPITILVPSTGY---------PRPTATWCF 6933
Query: 1591 GPDQTE----MTIEGLQPTVEYVVSVYAQNPSG----ESQPLVQTAVTNID--------R 1634
G E + ++ L E V+S ++ G + + V+T ID
Sbjct: 6934 GDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSA 6993
Query: 1635 PKGLAFTDVDVDSIKIAWESPQ----GQVSRY--------RVTYSSPEDGIHEL-FPAPD 1681
PK L F D+ DS+ + WE P ++ Y R T++ D + +L F PD
Sbjct: 6994 PKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPD 7053
Query: 1682 GEEDTAELQGLRPGSEYTVSVVALHDDMESQPL-------IGTQSTAIPAPTDLKFTQVT 1734
L G EY V A + +P + T +T P ++K+ T
Sbjct: 7054 ----------LVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRT 7103
Query: 1735 PTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKY 1788
S+ W PP ++ GY V P+ G K + + + V+GL Y
Sbjct: 7104 ANSIFLTWDPPKNDGGSRIKGYIVERCPR---GSDKWVACGEPVAETKMEVTGLEEGKWY 7160
Query: 1789 EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT-----------ITISWRTK 1837
V AL S+P++ P + D E +T+ TK
Sbjct: 7161 AYRVKALNRQGASKPSR----------PTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTK 7210
Query: 1838 TE---TITGFQVDAVPANGQTPIQRTIKPDVR----------SYTITGLQPGTDYKIYLY 1884
E T+TG P T +K D R + TI + +
Sbjct: 7211 IELPATVTG---KPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIE 7267
Query: 1885 TLNDNARSSPVV-IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEK 1939
+N R++ VV ++ P+ T S L++W PPR ++IT Y+++
Sbjct: 7268 AVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRA 7327
Query: 1940 PGSPPREVVPRPRPGV--TEATITGLEPGTEYTIYVIALKNNQKSEPL 1985
S EV + V T T L P EY V A EP+
Sbjct: 7328 TDS---EVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPV 7372
Score = 52.8 bits (125), Expect = 4e-06
Identities = 80/336 (23%), Positives = 120/336 (35%), Gaps = 46/336 (13%)
Query: 602 LQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKN-SVGRWKEA 657
++ Y S P + +T+ ++ S + W+AP S I+ Y++ R + W+E
Sbjct: 8995 VEVYDRPSPPRNLAVTDIKAE--SCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEV 9052
Query: 658 TIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
T Y I L P YE ++ ++ +YG + + D V + P
Sbjct: 9053 TNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSD-------KVVIQDPYRLPGPP 9105
Query: 718 FSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA----- 772
P V T S +VSW D Y L + + Y S A
Sbjct: 9106 GKPKVLAR------TKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKV 9159
Query: 773 ----TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPPD-PTVDQV 822
N+P LL G KY +N I E S P PP P V
Sbjct: 9160 GLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDK 9219
Query: 823 DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPE---TANSVTLSDLQPGVQ 875
+SI + W P +PI GY + +N P+ T + +L+ +
Sbjct: 9220 TKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRK 9279
Query: 876 YNITIYAVEENQESTPVVIQQETTG-TPRSDTVPSP 910
Y + AV E ES P +TTG P +D P
Sbjct: 9280 YRFRVKAVNEAGESEP----SDTTGEIPATDIQEEP 9311
Score = 43.9 bits (102), Expect = 0.002
Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 22/204 (10%)
Query: 717 PFSPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTA 772
P P+V + + +S V+SW +D ++ + VE ++EG E Q + +
Sbjct: 24229 PTGPIV-----IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISV 24283
Query: 773 TSVNIPDLLPGRKYIV-----NVYQISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTS 826
T+ I +L Y N + IS+ E S+++ S P AP PT+ V S
Sbjct: 24284 TTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDS 24343
Query: 827 IVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSV-TLSDLQPGVQYNITIY 881
VV W P A I Y + + + E +V ++ +L G++Y +
Sbjct: 24344 CVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVK 24403
Query: 882 AVEENQESTPVVIQQETTGTPRSD 905
ES I + TP+SD
Sbjct: 24404 CENLGGESEWSEISEPI--TPKSD 24425
Score = 41.2 bits (95), Expect = 0.012
Identities = 92/413 (22%), Positives = 157/413 (38%), Gaps = 51/413 (12%)
Query: 1285 VTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSV 1341
++W PP +TN++V K + +S + S + NL Y VS+
Sbjct: 24245 ISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQ 24304
Query: 1342 YEQHESTPLRGRQKTGLDSPTGID-------FSDITANSFTVHWIAPRATITGYRIRHHP 1394
S PL + SP + +T +S V W P A+ G +IR++
Sbjct: 24305 NTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAW-KPPASDGGAKIRNYY 24363
Query: 1395 EHFSGRPREDRVPHSRNSITLT-----NLTPGTEYVVSIVA--LNGREESPLLIGQQSTV 1447
+ + + + I T NL G EY + L G E + +
Sbjct: 24364 LEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPK 24423
Query: 1448 SDVP----------RDLEVVAATPTSLLISWDA-PAVTVRYYRITYGET----GGNSPVQ 1492
SDVP R+L V + +L+ P V++YR G+ G +Q
Sbjct: 24424 SDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYR--QGKEIIADGLKYRIQ 24481
Query: 1493 EFTVPGSKSTATISGLKPGVDYTITVYAV--TGRGDSPASSKPISINYRTEIDKPSQMQ- 1549
EF G I+ + D TVY V T +G S + + + + +I P ++
Sbjct: 24482 EFK--GGYHQLIIASV---TDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEG 24536
Query: 1550 ---VTDVQDNSISVKWLPSSS---PVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
V ++ +S+K +P S PV ++ + G + + + G++
Sbjct: 24537 MGAVHALRGEVVSIK-IPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVE 24595
Query: 1604 PTVEYVVSVYAQNPSGESQPLVQTAVTNI-DRPKGLAFTDVDVDSIKIAWESP 1655
V A+N G Q V+ V ++ D P+G+ +DV DS+ + W P
Sbjct: 24596 RKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEP 24648
Score = 39.3 bits (90), Expect = 0.046
Identities = 46/194 (23%), Positives = 75/194 (38%), Gaps = 22/194 (11%)
Query: 2062 PPTTATPIRH-RPRPYPPNVGQEALSQTTISWAPFQD-----TSEYIISCHPVGTDEEPL 2115
P T TP+ P PP V S ++SW+ +D + Y I TD+
Sbjct: 23822 PVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVR 23881
Query: 2116 QFRVPGTSTSATLTGLTRGATYNIIVEALKD---QQRHKVREEVVTVGNSVNEGLNQPTD 2172
+ T+T T+TGL A Y + A D + E VV + ++P+
Sbjct: 23882 HNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVV-----CKDPFDKPSQ 23936
Query: 2173 DSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEK 2232
+ ++S +V +WE+ G K + LG+ + + S W N K
Sbjct: 23937 PGELEILSISKDSVTLQWEKPECDGGK---EILGYWVEYRQSGDSAWKKSNKERIK---- 23989
Query: 2233 WDRQGENGQMMSCT 2246
D+Q G ++ T
Sbjct: 23990 -DKQFTIGGLLEAT 24002
Score = 37.7 bits (86), Expect = 0.13
Identities = 36/131 (27%), Positives = 53/131 (40%), Gaps = 8/131 (6%)
Query: 894 IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGE 949
I Q+T +D PR ++ +V+ V + WT P S +T Y V+ E
Sbjct: 24612 IDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATT--AE 24669
Query: 950 HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ--TTKLDAPTNLQFVN 1007
R+ +R T V L +Y F+V A + SKP + TK D + +
Sbjct: 24670 RWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDE 24729
Query: 1008 ETDSTVLVRWT 1018
E D T V T
Sbjct: 24730 EVDETREVSMT 24740
Score = 35.0 bits (79), Expect = 0.87
Identities = 38/169 (22%), Positives = 71/169 (42%), Gaps = 17/169 (10%)
Query: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL-PSS---SPVTGYRV 1574
Y V + K + ++ D P ++V+DV +S+++ W P+S S +T Y V
Sbjct: 24602 YVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIV 24661
Query: 1575 TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL--VQTAVTNI 1632
+ A +T T+ L Y V A+N G S+P + +T
Sbjct: 24662 EKCATTAERWLRVGQA--RETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKE 24719
Query: 1633 DRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPD 1681
D+ + + + D +VD + +VS + ++SS ++ + A D
Sbjct: 24720 DKTRAMNY-DEEVDETR--------EVSMTKASHSSTKELYEKYMIAED 24759
>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform 2
precursor [Homo sapiens]
Length = 1898
Score = 153 bits (387), Expect = 2e-36
Identities = 172/631 (27%), Positives = 264/631 (41%), Gaps = 71/631 (11%)
Query: 1402 REDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPR---DLEVVA 1458
+ED +P RN + L+N+ Y ++ G E+ Q TV +P+ DL V
Sbjct: 274 KEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATA----QVTVKALPKPPIDLVVTE 329
Query: 1459 ATPTSLLISWDAP-AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKPGVDYTI 1516
T TS+ ++WD+ + V YY I Y G P QE V G +T +I GL P +Y
Sbjct: 330 TTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQE--VDGVATTRYSIGGLSPFSEYAF 387
Query: 1517 TVYAVTGRGDSPASSKPISINYRTEIDKPS----QMQVTDVQDNSISVKWLPSSSP---V 1569
V AV G P S ++ RT PS ++Q + +++ V+W P P V
Sbjct: 388 RVLAVNSIGRGPPSE---AVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLV 444
Query: 1570 TGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG-LQPTVEYVVSVYAQNPSGESQPLVQTA 1628
GYRV TP + P D +T G L P + Y + V A G+ P
Sbjct: 445 RGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQ 504
Query: 1629 V-TNIDRPKGLAFTDVDVDS---IKIAWE-SPQGQVSRYRVTY--SSPEDGIHELFPAPD 1681
V T P A +V+S I+++W PQ ++ Y + Y + ED H++ P
Sbjct: 505 VKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPT 564
Query: 1682 GEEDTAELQGLRPGSEYTVSVVALHD--------DMESQPLIGTQSTAIPAPTDLKFTQV 1733
+ L+ L+P + Y + A D +E++ QST P + +
Sbjct: 565 S---SYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEART---AQSTPSAPPQKVMCVSM 618
Query: 1734 TPTSLSAQWTPP-----NVQLTGYRV--RVTPKEKTGPMKEINLAPDSSSVVVSGLMVAT 1786
T++ W PP N +T Y V E G ++ + SS + GL T
Sbjct: 619 GSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWT 678
Query: 1787 KYEVSVYALKDTLTSRPAQGV-VTTLENV--SPPRRARVTDATETTITISWRTKTET--- 1840
+Y V V A D + V V T E+V PPR+ V T + + W+ +
Sbjct: 679 EYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQH 738
Query: 1841 --ITGFQVDAVPANGQTP-----IQRTIKPDVRSYTITGLQPGTDYKIYLY---TLNDNA 1890
I G+QV V P IQ + + + TI+GL P T Y + + T D A
Sbjct: 739 GQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGA 798
Query: 1891 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR---ARITGYIIKYEKPGSPPREV 1947
RS P ++ + A+ + T N+ L+ W PP+ + GY ++Y +
Sbjct: 799 RSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRADEARPNT 858
Query: 1948 VPRPRPGVTEATITGLEPGTEYTIYVIALKN 1978
+ + T+TGL GT Y I+ +A KN
Sbjct: 859 IDFGKDD-QHFTVTGLHKGTTY-IFRLAAKN 887
Score = 142 bits (357), Expect = 5e-33
Identities = 167/722 (23%), Positives = 287/722 (39%), Gaps = 69/722 (9%)
Query: 1264 IPAVP-PPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNA 1322
+ A+P PP DL T ++ +TW S +T + ++Y E E+ +
Sbjct: 315 VKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVD-GVATTR 373
Query: 1323 VVLTNLLPGTEYVVSVSSVYEQHESTPLRG-RQKTGLDSPTG----IDFSDITANSFTVH 1377
+ L P +EY V +V P R +TG +P+ + ++A++ V
Sbjct: 374 YSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQ 433
Query: 1378 WIAPR---ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT---NLTPGTEYVVSIVAL 1431
W P + GYR+ + P+ S RP H+ ++ LT +L PG Y + ++A
Sbjct: 434 WEPPEEPNGLVRGYRVYYTPD--SRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAF 491
Query: 1432 NGREESP----LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT-VRYYRITYGETG 1486
+ P + + Q V P D + + T + +SW P + Y + Y
Sbjct: 492 TAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAE 551
Query: 1487 GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS 1546
+ T + S+ T+ LKP Y + + R D +I RT PS
Sbjct: 552 DEDQQHKVTFDPT-SSYTLEDLKPDTLYR---FQLAARSDMGVGVFTPTIEARTAQSTPS 607
Query: 1547 ----QMQVTDVQDNSISVKWLPSSSP-----VTGYRVTTTPKNGPGPTKTKTAG--PDQT 1595
++ + ++ V W+P + +T Y V +G + G + +
Sbjct: 608 APPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHS 667
Query: 1596 EMTIEGLQPTVEYVVSVYAQN---PSGESQPLVQTAVTNIDR--PKGLAFTDVDVDSIKI 1650
+ GL+ EY V V A P ES P++ ++ P+ + ++ ++ +
Sbjct: 668 SWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHV 727
Query: 1651 AWESP-----QGQVSRYRVTYSSPEDGIHELFPAPD----GEEDTAELQGLRPGSEYTVS 1701
W+ P GQ+ Y+VTY E+G P E + GL P + Y+V+
Sbjct: 728 YWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTPETTYSVT 787
Query: 1702 VVALH---DDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNV---QLTGYRVR 1755
V A D S+P I T + A+P + + + QW PP +L GYR++
Sbjct: 788 VAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGYRLQ 847
Query: 1756 VTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVS 1815
++ P I+ D V+GL T Y + A + + T E++
Sbjct: 848 YCRADEARP-NTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLP 906
Query: 1816 P--PRRARVTDATETTITISW-----RTKTETITGFQVDAVPANGQTPIQRTIKPDVRSY 1868
P+ VT T +T ++W + I + V N Q +Q I D R +
Sbjct: 907 SGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQN-ITTDTR-F 964
Query: 1869 TITGLQPGTDY--KIYLYTLNDNARSSPVVIDASTAIDA--PSNLRFLATTPNSLLVSWQ 1924
T+TGL+P T Y K+ +T + SP + + ++ N R A S+L+SW+
Sbjct: 965 TLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWE 1024
Query: 1925 PP 1926
P
Sbjct: 1025 VP 1026
Score = 134 bits (338), Expect = 8e-31
Identities = 178/753 (23%), Positives = 299/753 (39%), Gaps = 71/753 (9%)
Query: 1053 LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA-- 1110
L N+ ++ YT ++ G E+ V +P I TE T T++ +TW
Sbjct: 287 LSNVVRSANYTCVAISSLGMIEATAQVTVKALPKP--PIDLVVTETTATSVTLTWDSGNS 344
Query: 1111 -PRIGFKLGVRPSQGGEAPREVTSDSGSI--VVSGLTPGVEYVYTIQVLRD-GQERDAPI 1166
P + + R + G E P + + + GL+P EY + + + G+ +
Sbjct: 345 EPVTYYGIQYRAA-GTEGPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEA 403
Query: 1167 VNKVV---TPLSPPTNLHLEANPDTGVLTVSWERSTTPD--ITGYRITTTPTNGQQGNSL 1221
V P SPP + + +L V WE P+ + GYR+ TP + + N+
Sbjct: 404 VRARTGEQAPSSPPRRVQARMLSASTML-VQWEPPEEPNGLVRGYRVYYTPDSRRPPNAW 462
Query: 1222 EEVVHADQSSCTFDNLSPGLEYNVSVYT---VKDDKESVPISDTIIPAVPP-PTDLRFTN 1277
+ T +L PG+ Y++ V V D S I VP P D +
Sbjct: 463 HKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEV 522
Query: 1278 IGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVS 1337
++++W PP + + + Y ++E+ +++ P+ ++ L +L P T Y
Sbjct: 523 ESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPT-SSYTLEDLKPDTLYRFQ 581
Query: 1338 VSSVYEQHES--TPL---RGRQKTGLDSPTGIDFSDITANSFTVHWIAPRA-----TITG 1387
+++ + TP R Q T P + + + + V W+ P A IT
Sbjct: 582 LAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQ 641
Query: 1388 YRIRHHPEHFSGRPRE--DRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLLI 1441
Y + + R R D + +S L L TEY V + A G E SP+L+
Sbjct: 642 YSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLV 701
Query: 1442 GQQSTV-SDVPRDLEVVAATPTSLLISWDAPAVT-----VRYYRITY-----GETGGNSP 1490
V S PR +EV T++ + W P + +R Y++TY GE G
Sbjct: 702 RTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPI 761
Query: 1491 VQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQV 1550
+Q+ + ++ T TISGL P Y++TV A T +GD A SKP + + M +
Sbjct: 762 IQDVMLAEAQET-TISGLTPETTYSVTVAAYTTKGDG-ARSKPKIVTTTGAVPGRPTMMI 819
Query: 1551 TDVQDNSISVKWLPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVE 1607
+ N+ ++W P + GYR+ + P T G D T+ GL
Sbjct: 820 STTAMNTALLQWHPPKELPGELLGYRLQYCRADEARP-NTIDFGKDDQHFTVTGLHKGTT 878
Query: 1608 YVVSVYAQNPSGESQPLVQTAVTNIDRPKG----LAFTDVDVDSIKIAWESP-----QGQ 1658
Y+ + A+N +G + + T D P G L T + + ++AW+ P G+
Sbjct: 879 YIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGR 938
Query: 1659 VSRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGT 1717
+ Y V + I+ + DT L GL+P + Y + V A
Sbjct: 939 IISYTVVFRD----INSQQELQNITTDTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSI 994
Query: 1718 QSTAIPA----PTDLKFTQVTPTSLSAQWTPPN 1746
QS +P + + TS+ W P+
Sbjct: 995 QSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPD 1027
Score = 130 bits (328), Expect = 1e-29
Identities = 177/732 (24%), Positives = 297/732 (40%), Gaps = 84/732 (11%)
Query: 1308 EEDVAELSISPSDNAVVLTNLLPGTEYV-VSVSSV--YEQHESTPLRGRQKTGLDSPTGI 1364
EE E + N + L+N++ Y V++SS+ E ++ K +D +
Sbjct: 270 EELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTVKALPKPPID----L 325
Query: 1365 DFSDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPRE-DRVPHSRNSITLTNLTPGT 1422
++ TA S T+ W + + +T Y I++ G +E D V +R SI L+P +
Sbjct: 326 VVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVDGVATTRYSIG--GLSPFS 383
Query: 1423 EYVVSIVALNGREESP------LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT-- 1474
EY ++A+N P G+Q+ S PR ++ + +++L+ W+ P
Sbjct: 384 EYAFRVLAVNSIGRGPPSEAVRARTGEQAP-SSPPRRVQARMLSASTMLVQWEPPEEPNG 442
Query: 1475 -VRYYRITYGETGGNSPV---QEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS 1530
VR YR+ Y P + T G +T + L PG+ Y++ V A T GD P S
Sbjct: 443 LVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTT--VGSLLPGITYSLRVLAFTAVGDGPPS 500
Query: 1531 SKPISINYRTEIDKPSQ---MQVTDVQDNSISVKWL-PSSSPVTGYRVTTTPKNGPGPTK 1586
+I +T+ P+Q Q D I + WL P + Y +
Sbjct: 501 P---TIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQH 557
Query: 1587 TKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES--QPLVQTAV---TNIDRPKGLAFT 1641
T P + T+E L+P Y + A++ G P ++ T P+ +
Sbjct: 558 KVTFDPTSS-YTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCV 616
Query: 1642 DVDVDSIKIAWESP-----QGQVSRYRVTYSSP--EDGIHELFPAPDGEEDTAELQGLRP 1694
+ +++++W P G +++Y V Y + ED + E + +L GL
Sbjct: 617 SMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEK 676
Query: 1695 GSEYTVSVVALHDDM----ESQPLIGTQSTAIPA--PTDLKFTQVTPTSLSAQWTPP--- 1745
+EY V V A H D+ ES P++ +P+ P ++ + T++ W P
Sbjct: 677 WTEYRVWVRA-HTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPS 735
Query: 1746 --NVQLTGYRVRVTPKEKTGP-----MKEINLAPDSSSVVVSGLMVATKYEVSVYALK-- 1796
+ Q+ GY+V E P ++++ LA ++ +SGL T Y V+V A
Sbjct: 736 KQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLA-EAQETTISGLTPETTYSVTVAAYTTK 794
Query: 1797 -DTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTET---ITGFQVDAVPAN 1852
D S+P +VTT V ++ T + W E + G+++ A+
Sbjct: 795 GDGARSKPK--IVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRAD 852
Query: 1853 GQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPS----N 1908
P D + +T+TGL GT Y L N + T D PS N
Sbjct: 853 EARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQN 912
Query: 1909 LRFLATTPNSLLVSWQPP-----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGL 1963
L T ++ ++W PP RI Y + + S + + T T+TGL
Sbjct: 913 LHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINS---QQELQNITTDTRFTLTGL 969
Query: 1964 EPGTEYTIYVIA 1975
+P T Y I V A
Sbjct: 970 KPDTTYDIKVRA 981
Score = 117 bits (293), Expect = 1e-25
Identities = 188/815 (23%), Positives = 313/815 (38%), Gaps = 87/815 (10%)
Query: 862 ANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQ----ETTGTPRSDTVPSPR-DLQFV 916
A +T D P + + + V + T V I E T +P P DL
Sbjct: 269 AEELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVT 328
Query: 917 EVTDVKVTIMWTPPESA-VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYF 975
E T VT+ W S VT Y + G Q + T + GLSP Y F
Sbjct: 329 ETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPF-QEVDGVATTRYSIGGLSPFSEYAF 387
Query: 976 KVFAVS---HGRESKPLTAQ--QTTKLDAPTNLQFVNETDSTVLVRWTP---PRAQITGY 1027
+V AV+ G S+ + A+ + P +Q + ST+LV+W P P + GY
Sbjct: 388 RVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGY 447
Query: 1028 RLTVGLTRRGQP---RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTT 1084
R+ R P ++N + + +L P Y++ ++A + P + +
Sbjct: 448 RVYYTPDSRRPPNAWHKHNTDAGLLT-TVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVK 506
Query: 1085 LQPGSSIPP--YNTEV-TETTIVITWTPAPR---IGFKLGVRPSQGGEAPREVTSD-SGS 1137
Q G P + EV ++T I ++W P+ I ++L ++ + +VT D + S
Sbjct: 507 TQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPTSS 566
Query: 1138 IVVSGLTPGVEYVYTIQVLRD-GQERDAPIVNKVV---TPLSPPTNLHLEANPDTGVLTV 1193
+ L P Y + + D G P + TP +PP + + T V V
Sbjct: 567 YTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTV-RV 625
Query: 1194 SW----ERSTTPDITGYRITTTPTNGQ-QGNSLEEVVHADQSSCTFDNLSPGLEYNVSVY 1248
SW S IT Y + +G+ +G + + + + SS L EY V V
Sbjct: 626 SWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVR 685
Query: 1249 TVKD---DKESVPI---SDTIIPAVPPPTDLRFTNIGPDTMRVTW-APPPSI---DLTNF 1298
D ES P+ +D +P+ PP + + + V W P PS + +
Sbjct: 686 AHTDVGPGPESSPVLVRTDEDVPS-GPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGY 744
Query: 1299 LVRYSPVKNEED-----VAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR 1353
V Y ++N E + ++ ++ + + + L P T Y V+V++ + + R
Sbjct: 745 QVTYVRLENGEPRGLPIIQDVMLAEAQETTI-SGLTPETTYSVTVAAYTTKGDG----AR 799
Query: 1354 QKTGLDSPTG-------IDFSDITANSFTVHWIAPR---ATITGYRIRHHPEHFSGRPRE 1403
K + + TG + S N+ + W P+ + GYR+++ RP
Sbjct: 800 SKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRAD-EARPNT 858
Query: 1404 DRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTVSDVPRDLEVVAA 1459
T+T L GT Y+ + A N G E + + S P++L V
Sbjct: 859 IDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGL 918
Query: 1460 TPTSLLISWDAPAVTVR-----YYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDY 1514
T ++ ++WD P + R Y + + + +Q T + + T++GLKP Y
Sbjct: 919 TTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNIT---TDTRFTLTGLKPDTTY 975
Query: 1515 TITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW-LPSSSPVTGYR 1573
I V A T +G P S S E +V S+ + W +P S Y+
Sbjct: 976 DIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDS-----YK 1030
Query: 1574 VTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEY 1608
K + G ++ I LQP EY
Sbjct: 1031 SAVPFKILYNGQSVEVDGHSMRKL-IADLQPNTEY 1064
Score = 114 bits (285), Expect = 1e-24
Identities = 171/774 (22%), Positives = 289/774 (37%), Gaps = 82/774 (10%)
Query: 990 TAQQTTKL--DAPTNLQFVNETDSTVLVRWTPPRAQ-ITGYRLTVGLTRRGQPRQYNVGP 1046
TAQ T K P +L T ++V + W ++ +T Y + P Q G
Sbjct: 310 TAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVDGV 369
Query: 1047 SVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV-FTTLQPGSSIPPYNTE---VTETT 1102
+ ++Y + L P SEY ++A+ P + V T + S PP + ++ +T
Sbjct: 370 ATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSAST 429
Query: 1103 IVITWTPAPR-----IGFKLGVRPS--QGGEAPREVTSDSGSI-VVSGLTPGVEY---VY 1151
+++ W P G+++ P + A + +D+G + V L PG+ Y V
Sbjct: 430 MLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVL 489
Query: 1152 TIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTT 1211
+ DG V + P + E DT + +SW I Y +
Sbjct: 490 AFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRI-QLSWLLPPQERIIMYELVYW 548
Query: 1212 PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV---PISDTIIPAVP 1268
+ + +V SS T ++L P Y + D V I + P
Sbjct: 549 AAEDE--DQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTP 606
Query: 1269 --PPTDLRFTNIGPDTMRVTWAPPPSID----LTNFLVRYSPVKNEEDVAEL--SISPSD 1320
PP + ++G T+RV+W PPP+ +T + V Y V E+ + IS
Sbjct: 607 SAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREH 666
Query: 1321 NAVVLTNLLPGTEYVVSV---SSVYEQHESTPLRGRQKTGLDS--PTGIDFSDITANSFT 1375
++ L L TEY V V + V ES+P+ R + S P ++ + + +
Sbjct: 667 SSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVH 726
Query: 1376 VHWIAP-----RATITGYRIRHHPEHFSGRPR-----EDRVPHSRNSITLTNLTPGTEYV 1425
V+W P I GY++ + +G PR +D + T++ LTP T Y
Sbjct: 727 VYWKLPVPSKQHGQIRGYQVT-YVRLENGEPRGLPIIQDVMLAEAQETTISGLTPETTYS 785
Query: 1426 VSIVAL----NGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAV---TVRYY 1478
V++ A +G P ++ V P + A T+LL W P + Y
Sbjct: 786 VTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALL-QWHPPKELPGELLGY 844
Query: 1479 RITYGETGGNSPVQEFTVPGSKSTA--TISGLKPGVDYTITVYAVTGRGDSPASSKPISI 1536
R+ Y P T+ K T++GL G Y + A G K I
Sbjct: 845 RLQYCRADEARP---NTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRT 901
Query: 1537 NYRTEIDKPSQMQVTDVQDNSISVKWLP-----SSSPVTGYRVTTTPKNGPGPTKTKTAG 1591
P + VT + ++ + W P + + Y V N + T
Sbjct: 902 PEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNITT- 960
Query: 1592 PDQTEMTIEGLQPTVEYVVSV--YAQNPSGESQPLVQTAVTNIDR--PKGLAFTDVDVDS 1647
T T+ GL+P Y + V + SG P +Q+ +++ K S
Sbjct: 961 --DTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTS 1018
Query: 1648 IKIAWESPQGQVSR--YRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYT 1699
+ ++WE P S +++ Y+ + DG + L+P +EY+
Sbjct: 1019 VLLSWEVPDSYKSAVPFKILYNGQSVEV-------DGHSMRKLIADLQPNTEYS 1065
Score = 105 bits (261), Expect = 7e-22
Identities = 198/893 (22%), Positives = 353/893 (39%), Gaps = 110/893 (12%)
Query: 1087 PGSSIPPYNTEV-----TETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVS 1141
P SIPP + EV T V P P + + +G + E+ + +S
Sbjct: 232 PRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKED---EMPVGRNVLELS 288
Query: 1142 GLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTP 1201
+ Y E A + K + PP +L + T V T++W+ +
Sbjct: 289 NVVRSANYTCVAISSLGMIEATAQVTVKALP--KPPIDLVVTETTATSV-TLTWDSGNSE 345
Query: 1202 DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD-----DKES 1256
+T Y I G +G +EV + + LSP EY V V E+
Sbjct: 346 PVTYYGIQYRAA-GTEG-PFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEA 403
Query: 1257 VPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP--PSIDLTNFLVRYSPVKNEEDVAEL 1314
V PP ++ + TM V W PP P+ + + V Y+P A
Sbjct: 404 VRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWH 463
Query: 1315 SISPSDNAVVLT--NLLPGTEY---VVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDI 1369
+ +D ++ T +LLPG Y V++ ++V + S ++ + + G+ + +++
Sbjct: 464 KHN-TDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEV 522
Query: 1370 TANS-FTVHWIAP-RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVS 1427
+++ + W+ P + I Y + + + + + +S TL +L P T Y
Sbjct: 523 ESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPT-SSYTLEDLKPDTLYRFQ 581
Query: 1428 IVALNGREE---SPLLIGQ--QSTVSDVPRDLEVVAATPTSLLISWDAPAVTVR-----Y 1477
+ A + +P + + QST S P+ + V+ T++ +SW P R
Sbjct: 582 LAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQ 641
Query: 1478 YRITY----GETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKP 1533
Y + Y GE G V + S+ + GL+ +Y + V A T G P SS P
Sbjct: 642 YSVAYEAVDGEDRGRHVVDG--ISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESS-P 698
Query: 1534 ISINYRTEIDKPS----QMQVTDVQDNSISVKW---LPSSS--PVTGYRVTTTP-KNGPG 1583
+ + RT+ D PS +++V + ++ V W +PS + GY+VT +NG
Sbjct: 699 VLV--RTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEP 756
Query: 1584 ---PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE---SQPLVQTAVTNIDRPKG 1637
P + E TI GL P Y V+V A G+ S+P + T +
Sbjct: 757 RGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPT 816
Query: 1638 LAFTDVDVDSIKIAWESPQ---GQVSRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLR 1693
+ + +++ + W P+ G++ YR+ Y ++ G++D + GL
Sbjct: 817 MMISTTAMNTALLQWHPPKELPGELLGYRLQYCRADEARPNTIDF--GKDDQHFTVTGLH 874
Query: 1694 PGSEYTVSVVA-----LHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP--- 1745
G+ Y + A L ++ E + + + P +L T +T ++ W PP
Sbjct: 875 KGTTYIFRLAAKNRAGLGEEFEKE-IRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLA 933
Query: 1746 --NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP 1803
N ++ Y V +E+ + ++GL T Y++ V A TS+
Sbjct: 934 ERNGRIISYTVVF---RDINSQQELQNITTDTRFTLTGLKPDTTYDIKVRAW----TSKG 986
Query: 1804 AQGVVTTLENVSPP------RRARVTDATETTITISWRTKTETITGFQVDAVPA----NG 1853
+ + ++++ + P + RV A +T++ +SW + AVP NG
Sbjct: 987 SGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWE-----VPDSYKSAVPFKILYNG 1041
Query: 1854 QTPIQRTIKPDVRSYT--ITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAID 1904
Q+ ++ D S I LQP T+Y L +A ++ TA D
Sbjct: 1042 QS-----VEVDGHSMRKLIADLQPNTEYSFVLMNRGSSAGGLQHLVSIRTAPD 1089
Score = 86.7 bits (213), Expect = 3e-16
Identities = 125/566 (22%), Positives = 223/566 (39%), Gaps = 67/566 (11%)
Query: 628 IQWNAPQPSHISKY-ILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQ 686
+ W P I Y ++ W ++ + K P +SYT++ LKP +Y QL +
Sbjct: 530 LSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDP--TSSYTLEDLKPDTLYRFQLAARSD 587
Query: 687 YGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV----- 741
G T T+ STP + P ++ S T + VSWV
Sbjct: 588 MGVGVFTPTIEARTAQSTP---------SAPPQKVMCVSMGSTTVR-----VSWVPPPAD 633
Query: 742 SASDTVSGFRVEYELSEEGDEPQYL--DLPSTATSVNIPDLLPGRKYIVNVYQISEDG-- 797
S + ++ + V YE + D +++ + +S ++ L +Y V V ++ G
Sbjct: 634 SRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPG 693
Query: 798 -EQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVRW-----SRPQAPITGYRIVYSPSVE 850
E S +L + P PP V+ ++ T++ V W S+ I GY++ Y
Sbjct: 694 PESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLEN 753
Query: 851 GSSTELNLPE-----TANSVTLSDLQPGVQYNITIYAVE---ENQESTPVVIQQETTGTP 902
G L + + A T+S L P Y++T+ A + S P ++ TTG
Sbjct: 754 GEPRGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIV--TTTG-- 809
Query: 903 RSDTVPSPRDLQFVEVTDVKVTIM-WTPPE---SAVTGYRVDVIPVNLPGEHGQRLPISR 958
VP R + T + ++ W PP+ + GYR+ + +
Sbjct: 810 ---AVPG-RPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRADEARPNTIDFGKDD 865
Query: 959 NTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT----NLQFVNETDSTVL 1014
F VTGL G TY F++ A + + + T D P+ NL T ST
Sbjct: 866 QHFT-VTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTE 924
Query: 1015 VRWTPP-RAQITGYRLTVGLTRR---GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIK 1070
+ W PP A+ G ++ + R Q N+ + +++ L L+P + Y + + A
Sbjct: 925 LAWDPPVLAERNGRIISYTVVFRDINSQQELQNI-TTDTRFTLTGLKPDTTYDIKVRAWT 983
Query: 1071 GNQESPKATGVFTTLQPGSSIPPYNTEVT---ETTIVITWTPAPRIGFKLGVRPSQGGEA 1127
P + + + P + N V +T+++++W + + G++
Sbjct: 984 SKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYNGQS 1043
Query: 1128 PREVTSDSGSIVVSGLTPGVEYVYTI 1153
EV S +++ L P EY + +
Sbjct: 1044 V-EVDGHSMRKLIADLQPNTEYSFVL 1068
>gi|119220552 sidekick 1 [Homo sapiens]
Length = 2213
Score = 152 bits (383), Expect = 5e-36
Identities = 270/1177 (22%), Positives = 447/1177 (37%), Gaps = 183/1177 (15%)
Query: 923 VTIMWTPP---ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA 979
V + W P S + Y V++ N P + T V+GL+P TY F+V A
Sbjct: 686 VVLSWVRPFDGNSPILYYIVELSENNSPWKVHLSNVGPEMTGVTVSGLTPARTYQFRVCA 745
Query: 980 VS------HGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP---------RAQI 1024
V+ + E+ L + P N+ T+ +++V+W PP R I
Sbjct: 746 VNEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRTNQSIMVQWQPPPETEHNGVLRGYI 805
Query: 1025 TGYRLTVGLTRRGQPRQYNV-GPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT 1083
YRL GL G+ +Q N+ P V+ + +L ++Y + + A G GVF+
Sbjct: 806 LRYRLA-GLP--GEYQQRNITSPEVNYCLVTDLIIWTQYEIQVAAYNG-----AGLGVFS 857
Query: 1084 ------TLQPGSSIPPYNTE---VTETTIVITWTPAPRI-------GFKLGVRPSQGGEA 1127
TLQ + PP N + V TTI W P P+ G+KL P+ EA
Sbjct: 858 RAVTEYTLQGVPTAPPQNVQTEAVNSTTIQFLWNPPPQQFINGINQGYKLLAWPADAPEA 917
Query: 1128 PREVT--SDSGSIVVSGLTPGVEYV-YTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEA 1184
VT D + +T ++ Y VL D P P +P E
Sbjct: 918 VTVVTIAPDFHGVHHGHITNLKKFTAYFTSVLCFTTPGDGP-------PSTPQLVWTQED 970
Query: 1185 NP------------DTGVLTVSWERSTTPD--ITGYRITTTPTNGQQGNSLEEVVHADQS 1230
P DT L VSW+ + ITGY+I+ G+ + L +++
Sbjct: 971 KPGAVGHLSFTEILDTS-LKVSWQEPLEKNGIITGYQISWE-VYGRNDSRLTHTLNSTTH 1028
Query: 1231 SCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPP-----PTDLRFTNIGPDTMRV 1285
LS Y + V V + S TI VPP P++L +NI P + +
Sbjct: 1029 EYKIQGLSSLTTYTIDVAAVTAVGTGLVTSSTISSGVPPDLPGAPSNLVISNISPRSATL 1088
Query: 1286 TWAP--PPSIDLTNFLV--RYSPVKNEED---VAELSISPSDNAVVLTNLLPGTEYVVSV 1338
+ P ++ ++V + + +EE+ + E P + + NL P T Y +
Sbjct: 1089 QFRPGYDGKTSISRWIVEGQVGAIGDEEEWVTLYEEENEPDAQMLEIPNLTPYTHYRFRM 1148
Query: 1339 SSVY------EQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA-------PRATI 1385
V S ++ Q +PT + + S + W+
Sbjct: 1149 KQVNIVGPSPYSPSSRVIQTLQAPPDVAPTSVTVRTASETSLRLRWVPLPDSQYNGNPES 1208
Query: 1386 TGYRIRHHPEHFSGRPREDRVPHS-RNSITLTNLTPGTEYVVSIVALNGREESP---LLI 1441
GYRI++ V T+ L EY + + A N P ++
Sbjct: 1209 VGYRIKYWRSDLQSSAVAQVVSDRLEREFTIEELEEWMEYELQMQAFNAVGAGPWSEVVR 1268
Query: 1442 GQ--QSTVSDVPRDLEVVAATPTSLLISWDAPAVT-----VRYYRITYGETGGNSPVQEF 1494
G+ +S S P ++ A + T +L++W + + Y+I + + +
Sbjct: 1269 GRTRESVPSAAPENVSAEAVSSTQILLTWTSVPEQDQNGLILGYKILFRAKDLDPEPRSH 1328
Query: 1495 TVPGSKS-TATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS---QMQV 1550
V G+ + +A ++GL+ V Y + V A T G+ S+ P+ + RT+ D P ++
Sbjct: 1329 IVRGNHTQSALLAGLRKFVLYELQVLAFTRIGNGVPST-PLILE-RTKDDAPGPPVRLVF 1386
Query: 1551 TDVQDNSISVKWLPSSSP---VTGYRVT-TTPKNGPGPTKTKTAGPDQTEMTIEGLQPTV 1606
+V+ S+ + W P P + GY++ + P T G + T L P
Sbjct: 1387 PEVRLTSVRIVWQPPEEPNGIILGYQIAYRLASSSPHTFTTVEVGATVRQFTATDLAPES 1446
Query: 1607 EYVVSVYAQNPSGESQPLVQTAVTNIDR-----PKGLAFTDVDVD--SIKIAWESPQGQV 1659
Y+ + A+ G +PL T +T R P+ L +V S+++ W
Sbjct: 1447 AYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQAEVTARSLRLQWVPGSDGA 1506
Query: 1660 SRYRVTYSSPED---GIHELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHD----DMES 1711
S R + G + + + E TA + LRP + Y + + A +D D S
Sbjct: 1507 SPIRYFTMQVRELPRGEWQTYSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSS 1566
Query: 1712 QPLIGTQSTAIPA--PTDLKFTQVTPTSLSAQWTPP-----NVQLTGYRVRVTPKE---- 1760
+ T +P P + T T +S+ QW PP N L GYR+ E
Sbjct: 1567 ETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLNGLLQGYRIYYRELEYEAG 1626
Query: 1761 -----KT--------------GPMKEINLAPDSSSVVVSGLMVATKYEVSVYA---LKDT 1798
KT K +N + S+ ++ L +YEV + A + ++
Sbjct: 1627 SGTEAKTLKNPIALHAELTAQSSFKTVNSSSTSTMCELTHLKKYRRYEVIMTAYNIIGES 1686
Query: 1799 LTSRPAQGVVTTLENVSPPRRARVTDATETTITISW-----RTKTETITGFQVDAVPANG 1853
S P + V P+ +VT T + + ++W ++ I G+++ A+
Sbjct: 1687 PASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDPPPPESQNGNIQGYKIYYWEADS 1746
Query: 1854 QTPIQRTI-----KPDVRSYTITGLQPGTDYKIYLYTLN---DNARSSPVVIDASTAID- 1904
Q ++ +P VR +T T Y + + N D +S P A
Sbjct: 1747 QNETEKMKVLFLPEPVVRLKNLTS---HTKYLVSISAFNAAGDGPKSDPQQGRTHQAAPG 1803
Query: 1905 APSNLRFLATTPNSLLVSWQPPRAR---ITGYIIKYE 1938
APS L F T +L VSW P A + GY + YE
Sbjct: 1804 APSFLAFSEITSTTLNVSWGEPAAANGILQGYRVVYE 1840
Score = 150 bits (378), Expect = 2e-35
Identities = 280/1336 (20%), Positives = 488/1336 (36%), Gaps = 191/1336 (14%)
Query: 737 VVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA---TSVNIPDLLPGRKYIVNVYQI 793
V+SWV D S E + P + L + T V + L P R Y V +
Sbjct: 687 VLSWVRPFDGNSPILYYIVELSENNSPWKVHLSNVGPEMTGVTVSGLTPARTYQFRVCAV 746
Query: 794 SEDGEQSLILSTSQTTAPDAPPDPTVDQV-----DDTSIVVRWSRP---------QAPIT 839
+E G TS+ P+ PP + + SI+V+W P + I
Sbjct: 747 NEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRTNQSIMVQWQPPPETEHNGVLRGYIL 806
Query: 840 GYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETT 899
YR+ P E + PE N ++DL QY I + A N V + T
Sbjct: 807 RYRLAGLPG-EYQQRNITSPE-VNYCLVTDLIIWTQYEIQVAAY--NGAGLGVFSRAVTE 862
Query: 900 GTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAV-----TGYRVDVIPVNLPGEHGQRL 954
T + P+++Q V + +W PP GY++ P + P E +
Sbjct: 863 YTLQGVPTAPPQNVQTEAVNSTTIQFLWNPPPQQFINGINQGYKLLAWPADAP-EAVTVV 921
Query: 955 PISRN----TFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ----QTTKLDAPTNLQFV 1006
I+ + +T L Y+ V + + P T Q Q K A +L F
Sbjct: 922 TIAPDFHGVHHGHITNLKKFTAYFTSVLCFTTPGDGPPSTPQLVWTQEDKPGAVGHLSFT 981
Query: 1007 NETDSTVLVRWTPPRAQ---ITGYRLTVGLTRRGQPR-QYNVGPSVSKYPLRNLQPASEY 1062
D+++ V W P + ITGY+++ + R R + + + +Y ++ L + Y
Sbjct: 982 EILDTSLKVSWQEPLEKNGIITGYQISWEVYGRNDSRLTHTLNSTTHEYKIQGLSSLTTY 1041
Query: 1063 TVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPS 1122
T+ + A+ + TG+ T+ S +PP ++ +P L RP
Sbjct: 1042 TIDVAAV-----TAVGTGLVTSSTISSGVPPDLPGAPSNLVISNISPR---SATLQFRPG 1093
Query: 1123 QGGEA------------------------PREVTSDSGSIVVSGLTPGVEYVYTI-QVLR 1157
G+ E D+ + + LTP Y + + QV
Sbjct: 1094 YDGKTSISRWIVEGQVGAIGDEEEWVTLYEEENEPDAQMLEIPNLTPYTHYRFRMKQVNI 1153
Query: 1158 DGQERDAPIVNKVVTPLSP----PTNLHLEANPDTGVLTVSW------ERSTTPDITGYR 1207
G +P + T +P PT++ + +T L + W + + P+ GYR
Sbjct: 1154 VGPSPYSPSSRVIQTLQAPPDVAPTSVTVRTASETS-LRLRWVPLPDSQYNGNPESVGYR 1212
Query: 1208 ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVY---TVKDDKESVPISDTII 1264
I ++ Q + V + T + L +EY + + V S +
Sbjct: 1213 IKYWRSDLQSSAVAQVVSDRLEREFTIEELEEWMEYELQMQAFNAVGAGPWSEVVRGRTR 1272
Query: 1265 PAVP--PPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDV-----AELSIS 1317
+VP P ++ + + +TW P D ++ Y + +D+ + +
Sbjct: 1273 ESVPSAAPENVSAEAVSSTQILLTWTSVPEQDQNGLILGYKILFRAKDLDPEPRSHIVRG 1332
Query: 1318 PSDNAVVLTNLLPGTEY---VVSVSSVYEQHESTPLRGRQKTGLDS---PTGIDFSDITA 1371
+ +L L Y V++ + + STPL ++T D+ P + F ++
Sbjct: 1333 NHTQSALLAGLRKFVLYELQVLAFTRIGNGVPSTPLI-LERTKDDAPGPPVRLVFPEVRL 1391
Query: 1372 NSFTVHW---IAPRATITGYRIRHHPEHFSGRP-REDRVPHSRNSITLTNLTPGTEYVVS 1427
S + W P I GY+I + S V + T T+L P + Y+
Sbjct: 1392 TSVRIVWQPPEEPNGIILGYQIAYRLASSSPHTFTTVEVGATVRQFTATDLAPESAYIFR 1451
Query: 1428 IVALNGRE-----ESPLLIGQQSTVSDVPRDLEVVAA--TPTSLLISW---DAPAVTVRY 1477
+ A + E+ ++ ++ PR+L V A T SL + W A +RY
Sbjct: 1452 LSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQAEVTARSLRLQWVPGSDGASPIRY 1511
Query: 1478 YRITYGE-TGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISI 1536
+ + E G ++ + + L+P Y + + A GDS SS+ ++
Sbjct: 1512 FTMQVRELPRGEWQTYSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAV 1571
Query: 1537 NYRTEI--DKPSQMQVTDVQDNSISVKWLPS-----SSPVTGYRV--------------T 1575
++ + P + T +S+ ++W P + + GYR+
Sbjct: 1572 TTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLNGLLQGYRIYYRELEYEAGSGTEA 1631
Query: 1576 TTPKN---------GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ 1626
T KN KT + T + L+ Y V + A N GES
Sbjct: 1632 KTLKNPIALHAELTAQSSFKTVNSSSTSTMCELTHLKKYRRYEVIMTAYNIIGESPASAP 1691
Query: 1627 TAV-----TNIDRPKGLAFTDVDVDSIKIAW-----ESPQGQVSRYRVTY-SSPEDGIHE 1675
V P+ + T + +++ W ES G + Y++ Y + E
Sbjct: 1692 VEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDPPPPESQNGNIQGYKIYYWEADSQNETE 1751
Query: 1676 LFPAPDGEEDTAELQGLRPGSEYTVSVVALH---DDMESQPLIGTQSTAIP-APTDLKFT 1731
E L+ L ++Y VS+ A + D +S P G A P AP+ L F+
Sbjct: 1752 KMKVLFLPEPVVRLKNLTSHTKYLVSISAFNAAGDGPKSDPQQGRTHQAAPGAPSFLAFS 1811
Query: 1732 QVTPTSLSAQWTPP---NVQLTGYRV------------RVTPKEKTGPMKEINLAPDSSS 1776
++T T+L+ W P N L GYRV +V E G + D +
Sbjct: 1812 EITSTTLNVSWGEPAAANGILQGYRVVYEPLAPVQGVSKVVTVEVRGNWQRWLKVRDLTK 1871
Query: 1777 VVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISW-- 1834
V V + L+ +T+ PA+G + PR VT + + +T+ W
Sbjct: 1872 GVTYFFRVQARTITYGPELQANITAGPAEG------SPGSPRDVLVTKSA-SELTLQWTE 1924
Query: 1835 -RTKTETITGFQVDAVPANG--QTPIQRTIKPDVRSYTIT--GLQPGTDYKIYLYTLNDN 1889
+ TG+ ++A P++ + I SYT++ L+ G Y+ + +N+
Sbjct: 1925 GHSGDTPTTGYVIEARPSDEGLWDMFVKDIPRSATSYTLSLDKLRQGVTYEFRVVAVNEA 1984
Query: 1890 ARSSPVVIDASTAIDA 1905
P + STA+ A
Sbjct: 1985 GYGEP--SNPSTAVSA 1998
Score = 117 bits (292), Expect = 2e-25
Identities = 194/912 (21%), Positives = 338/912 (37%), Gaps = 129/912 (14%)
Query: 1138 IVVSGLTPGVEYVYTIQVLRD-GQERDAPIVNKVVTPLSPPT----NLHLEANPDTGVLT 1192
+ VSGLTP Y + + + + G+ + + ++++ P PP+ N+ + ++
Sbjct: 728 VTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRTNQSIM- 786
Query: 1193 VSWERSTTPDITG--------YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
V W+ + G YR+ P QQ N + + + C +L +Y
Sbjct: 787 VQWQPPPETEHNGVLRGYILRYRLAGLPGEYQQRN----ITSPEVNYCLVTDLIIWTQYE 842
Query: 1245 VSVYTVKDDKESV---PISDTIIPAVP--PPTDLRFTNIGPDTMRVTWAPPPSIDLTNFL 1299
+ V V +++ + VP PP +++ + T++ W PPP +
Sbjct: 843 IQVAAYNGAGLGVFSRAVTEYTLQGVPTAPPQNVQTEAVNSTTIQFLWNPPPQQFINGIN 902
Query: 1300 VRYS----PVKNEEDVAELSISPSDNAVV---LTNLLPGTEYVVSVSSVYEQHESTPLRG 1352
Y P E V ++I+P + V +TNL T Y SV + P
Sbjct: 903 QGYKLLAWPADAPEAVTVVTIAPDFHGVHHGHITNLKKFTAYFTSVLCFTTPGDGPPSTP 962
Query: 1353 RQK-TGLDSPTGI---DFSDITANSFTVHWIAP---RATITGYRIRHHPEHFSGRPREDR 1405
+ T D P + F++I S V W P ITGY+I GR + R
Sbjct: 963 QLVWTQEDKPGAVGHLSFTEILDTSLKVSWQEPLEKNGIITGYQISWE---VYGR-NDSR 1018
Query: 1406 VPHSRNSIT----LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATP 1461
+ H+ NS T + L+ T Y + + A+ L+ + S VP DL P
Sbjct: 1019 LTHTLNSTTHEYKIQGLSSLTTYTIDVAAVTAVGTG--LVTSSTISSGVPPDLP---GAP 1073
Query: 1462 TSLLISWDAPAVTVRYYRITY------------GETGGNSPVQEFTVPGSKSTAT----- 1504
++L+IS +P +R Y G+ G +E+ +
Sbjct: 1074 SNLVISNISPRSATLQFRPGYDGKTSISRWIVEGQVGAIGDEEEWVTLYEEENEPDAQML 1133
Query: 1505 -ISGLKPGVDYTITVYAVTGRGDSP--ASSKPISINYRTEIDKPSQMQVTDVQDNSISVK 1561
I L P Y + V G SP SS+ I P+ + V + S+ ++
Sbjct: 1134 EIPNLTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPPDVAPTSVTVRTASETSLRLR 1193
Query: 1562 WLP-------SSSPVTGYRVTTTPKNGPGPTKTKTAGPD-QTEMTIEGLQPTVEYVVSVY 1613
W+P + GYR+ + + + E TIE L+ +EY + +
Sbjct: 1194 WVPLPDSQYNGNPESVGYRIKYWRSDLQSSAVAQVVSDRLEREFTIEELEEWMEYELQMQ 1253
Query: 1614 AQNP----------SGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYR 1663
A N G ++ V +A + ++ T + + + + G + Y+
Sbjct: 1254 AFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQILLTWTSVPEQDQNGLILGYK 1313
Query: 1664 VTYSSPEDGIHELFPAP------DGEEDTAELQGLRPGSEYTVSVVA---LHDDMESQPL 1714
+ + + + L P P +A L GLR Y + V+A + + + S PL
Sbjct: 1314 ILFRAKD-----LDPEPRSHIVRGNHTQSALLAGLRKFVLYELQVLAFTRIGNGVPSTPL 1368
Query: 1715 I--GTQSTAIPAPTDLKFTQVTPTSLSAQWTPP---NVQLTGYRVRVT-PKEKTGPMKEI 1768
I T+ A P L F +V TS+ W PP N + GY++ +
Sbjct: 1369 ILERTKDDAPGPPVRLVFPEVRLTSVRIVWQPPEEPNGIILGYQIAYRLASSSPHTFTTV 1428
Query: 1769 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLEN---VSPPRRARVTDA 1825
+ + L + Y + A P + V T E +PPR V A
Sbjct: 1429 EVGATVRQFTATDLAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQA 1488
Query: 1826 --TETTITISWRTKTETITGF-----QVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTD 1878
T ++ + W ++ + QV +P +I + + + L+P T
Sbjct: 1489 EVTARSLRLQWVPGSDGASPIRYFTMQVRELPRGEWQTYSSSISHEATACVVDRLRPFTS 1548
Query: 1879 YKIYLYTLND------NARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----- 1927
YK+ L ND ++ + V + P ++ T +S+L+ WQPPR
Sbjct: 1549 YKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLN 1608
Query: 1928 ARITGYIIKYEK 1939
+ GY I Y +
Sbjct: 1609 GLLQGYRIYYRE 1620
Score = 102 bits (255), Expect = 3e-21
Identities = 233/1097 (21%), Positives = 407/1097 (37%), Gaps = 171/1097 (15%)
Query: 1043 NVGPSVSKYPLRNLQPASEYTVSLVAIKG---NQESPKATGVFTTLQPGSSIPPYNTEV- 1098
NVGP ++ + L PA Y + A+ Q S + + + +P S+ PP N
Sbjct: 720 NVGPEMTGVTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSA-PPKNIVAS 778
Query: 1099 --TETTIVITWTPAPRI-------GFKLGVRPS--QGGEAPREVTS-DSGSIVVSGLTPG 1146
T +I++ W P P G+ L R + G R +TS + +V+ L
Sbjct: 779 GRTNQSIMVQWQPPPETEHNGVLRGYILRYRLAGLPGEYQQRNITSPEVNYCLVTDLIIW 838
Query: 1147 VEYVYTIQVLRDGQERDAPIVNKVVT-------PLSPPTNLHLEANPDTGVLTVSWERST 1199
+Y + + ++ VT P +PP N+ EA T + + W
Sbjct: 839 TQYEIQVAAYNGA---GLGVFSRAVTEYTLQGVPTAPPQNVQTEAVNSTTIQFL-WNPPP 894
Query: 1200 TPDITG----YRITTTPTNGQQGNSLEEV------VHADQSSCTFDNLSPGLEYNVSVYT 1249
I G Y++ P + + ++ + VH + NL Y SV
Sbjct: 895 QQFINGINQGYKLLAWPADAPEAVTVVTIAPDFHGVHHGHIT----NLKKFTAYFTSVLC 950
Query: 1250 VKDDKESVPISDTIIPAVPPPTD----LRFTNIGPDTMRVTWAPPPSID--LTNFLVRYS 1303
+ P + ++ L FT I +++V+W P + +T + + +
Sbjct: 951 FTTPGDGPPSTPQLVWTQEDKPGAVGHLSFTEILDTSLKVSWQEPLEKNGIITGYQISWE 1010
Query: 1304 PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD---- 1359
+ +++ + + + L T Y + V++V +G+
Sbjct: 1011 VYGRNDSRLTHTLNSTTHEYKIQGLSSLTTYTIDVAAVTAVGTGLVTSSTISSGVPPDLP 1070
Query: 1360 -SPTGIDFSDITANSFTVHW---IAPRATITGYRIRHH------PEHFSGRPREDRVPHS 1409
+P+ + S+I+ S T+ + + +I+ + + E + E+ P +
Sbjct: 1071 GAPSNLVISNISPRSATLQFRPGYDGKTSISRWIVEGQVGAIGDEEEWVTLYEEENEPDA 1130
Query: 1410 RNSITLTNLTPGTEY-----VVSIVALNGREESPLLIGQQSTVSDV-PRDLEVVAATPTS 1463
+ + + NLTP T Y V+IV + S +I DV P + V A+ TS
Sbjct: 1131 Q-MLEIPNLTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPPDVAPTSVTVRTASETS 1189
Query: 1464 LLISWDAPAVTVRY--------YRITYGETG-GNSPVQEFTVPGSKSTATISGLKPGVDY 1514
L + W P +Y YRI Y + +S V + + TI L+ ++Y
Sbjct: 1190 LRLRW-VPLPDSQYNGNPESVGYRIKYWRSDLQSSAVAQVVSDRLEREFTIEELEEWMEY 1248
Query: 1515 TITVYAVTGRGDSPASSKPISINYRTEIDKPS----QMQVTDVQDNSISVKWLP-----S 1565
+ + A G P S + RT PS + V I + W
Sbjct: 1249 ELQMQAFNAVGAGPWSEV---VRGRTRESVPSAAPENVSAEAVSSTQILLTWTSVPEQDQ 1305
Query: 1566 SSPVTGYRVTTTPKN-GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP- 1623
+ + GY++ K+ P P G + GL+ V Y + V A G P
Sbjct: 1306 NGLILGYKILFRAKDLDPEPRSHIVRGNHTQSALLAGLRKFVLYELQVLAFTRIGNGVPS 1365
Query: 1624 ----LVQTAVTNIDRPKGLAFTDVDVDSIKIAW---ESPQGQVSRYRVTYSSPEDGIHEL 1676
L +T P L F +V + S++I W E P G + Y++ Y H
Sbjct: 1366 TPLILERTKDDAPGPPVRLVFPEVRLTSVRIVWQPPEEPNGIILGYQIAYRLASSSPHTF 1425
Query: 1677 FPAPDG---EEDTAELQGLRPGSEYTVSVVALHDDMESQPL----IGTQSTAIPAPTD-- 1727
G + TA L P S Y + A +PL I T+ PAP
Sbjct: 1426 TTVEVGATVRQFTAT--DLAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPREL 1483
Query: 1728 -LKFTQVTPTSLSAQWTPPN-----VQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSG 1781
+ +VT SL QW P + ++ +VR P+ + +++ ++++ VV
Sbjct: 1484 LVPQAEVTARSLRLQWVPGSDGASPIRYFTMQVRELPRGEWQTYSS-SISHEATACVVDR 1542
Query: 1782 LMVATKYEVSVYALKDTLTS--RPAQGVVTTLENV--SPPRRARVTDATETTITISWRTK 1837
L T Y++ + A D S VTTL++V PP T T +++ I W+
Sbjct: 1543 LRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPP 1602
Query: 1838 TET-----ITGFQV-------------------DAVPANGQTPIQRTIKPDVRSYT---- 1869
+ + G+++ + + + + Q + K S T
Sbjct: 1603 RDESLNGLLQGYRIYYRELEYEAGSGTEAKTLKNPIALHAELTAQSSFKTVNSSSTSTMC 1662
Query: 1870 -ITGLQPGTDYKIYLYTLN---DNARSSPVVIDASTAIDA--PSNLRFLATTPNSLLVSW 1923
+T L+ Y++ + N ++ S+PV + A A P N++ T + L V+W
Sbjct: 1663 ELTHLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTW 1722
Query: 1924 QPP-----RARITGYIIKYEKPGS----PPREVVPRPRPGVTEATITGLEPGTEYTIYVI 1974
PP I GY I Y + S +V+ P P V + L T+Y + +
Sbjct: 1723 DPPPPESQNGNIQGYKIYYWEADSQNETEKMKVLFLPEPVV---RLKNLTSHTKYLVSIS 1779
Query: 1975 ALK---NNQKSEPLIGR 1988
A + KS+P GR
Sbjct: 1780 AFNAAGDGPKSDPQQGR 1796
Score = 77.0 bits (188), Expect = 2e-13
Identities = 103/475 (21%), Positives = 184/475 (38%), Gaps = 52/475 (10%)
Query: 1513 DYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV--KWL---PSSS 1567
DY+ + + G A + I + + P + V+ +S +V W+ +S
Sbjct: 644 DYSCEIVSEGGNDSRMARLEVIELPH-----SPQNLLVSPNSSHSHAVVLSWVRPFDGNS 698
Query: 1568 PVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT 1627
P+ Y V + N P GP+ T +T+ GL P Y V A N G Q +T
Sbjct: 699 PILYYIVELSENNSPWKVHLSNVGPEMTGVTVSGLTPARTYQFRVCAVNEVGRGQYSAET 758
Query: 1628 AVTNIDR------PKGLAFTDVDVDSIKIAWESP---------QGQVSRYRVTYSSPEDG 1672
+ + PK + + SI + W+ P +G + RYR+ P +
Sbjct: 759 SRLMLPEEPPSAPPKNIVASGRTNQSIMVQWQPPPETEHNGVLRGYILRYRLA-GLPGEY 817
Query: 1673 IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD---DMESQPLIGTQSTAIPA--PTD 1727
+P E + + L ++Y + V A + + S+ + +P P +
Sbjct: 818 QQRNITSP--EVNYCLVTDLIIWTQYEIQVAAYNGAGLGVFSRAVTEYTLQGVPTAPPQN 875
Query: 1728 LKFTQVTPTSLSAQWTPPNVQL-----TGYRVRVTPKEKTGPMKEINLAPDSSSV---VV 1779
++ V T++ W PP Q GY++ P + + + +APD V +
Sbjct: 876 VQTEAVNSTTIQFLWNPPPQQFINGINQGYKLLAWPADAPEAVTVVTIAPDFHGVHHGHI 935
Query: 1780 SGLMVATKYEVSVYALKDTLTSRPA--QGVVTTLENVSPPRRARVTDATETTITISWR-- 1835
+ L T Y SV P+ Q V T + T+ +T++ +SW+
Sbjct: 936 TNLKKFTAYFTSVLCFTTPGDGPPSTPQLVWTQEDKPGAVGHLSFTEILDTSLKVSWQEP 995
Query: 1836 -TKTETITGFQVD-AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSS 1893
K ITG+Q+ V + + T+ Y I GL T Y I + + A +
Sbjct: 996 LEKNGIITGYQISWEVYGRNDSRLTHTLNSTTHEYKIQGLSSLTTYTIDVAAV--TAVGT 1053
Query: 1894 PVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVV 1948
+V ++ + P + L P++L++S PR+ + Y+ S R +V
Sbjct: 1054 GLVTSSTISSGVPPD---LPGAPSNLVISNISPRSATLQFRPGYDGKTSISRWIV 1105
Score = 74.3 bits (181), Expect = 1e-12
Identities = 143/675 (21%), Positives = 244/675 (36%), Gaps = 109/675 (16%)
Query: 662 HLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPL 721
H S + GL+ V+YE Q+++ + G+ STP+ T + P P+
Sbjct: 1334 HTQSALLAGLRKFVLYELQVLAFTRIGN----------GVPSTPLILER-TKDDAPGPPV 1382
Query: 722 VATSESVTEITASSFVVSWVSASD---TVSGFRVEYELSEEGDEP-QYLDLPSTATSVNI 777
E+ +S + W + + G+++ Y L+ +++ +T
Sbjct: 1383 RLV---FPEVRLTSVRIVWQPPEEPNGIILGYQIAYRLASSSPHTFTTVEVGATVRQFTA 1439
Query: 778 PDLLPGRKYIVNVYQISEDG----EQSLILSTSQTTAPDAPPDPTVDQVDDT--SIVVRW 831
DL P YI + + G ++ +++T + P P + V Q + T S+ ++W
Sbjct: 1440 TDLAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQAEVTARSLRLQW 1499
Query: 832 ---SRPQAPITGY--RIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEE- 885
S +PI + ++ P E + ++ A + + L+P Y + + A +
Sbjct: 1500 VPGSDGASPIRYFTMQVRELPRGEWQTYSSSISHEATACVVDRLRPFTSYKLRLKATNDI 1559
Query: 886 -----NQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP-----ESAVT 935
+ E+ V Q+ G P +P T V I W PP +
Sbjct: 1560 GDSDFSSETEAVTTLQDVPGEPPGSVSATPH-------TTSSVLIQWQPPRDESLNGLLQ 1612
Query: 936 GYRVDVIPVNLPGEHGQ-----RLPI------------------SRNTFAEVTGLSPGVT 972
GYR+ + G + PI S +T E+T L
Sbjct: 1613 GYRIYYRELEYEAGSGTEAKTLKNPIALHAELTAQSSFKTVNSSSTSTMCELTHLKKYRR 1672
Query: 973 Y-----YFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP-----RA 1022
Y + + S + + AP N+Q T S + V W PP
Sbjct: 1673 YEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDPPPPESQNG 1732
Query: 1023 QITGYRLTV-GLTRRGQPRQYNV----GPSVSKYPLRNLQPASEYTVSLVAIKGNQESPK 1077
I GY++ + + + V P V L+NL ++Y VS+ A + PK
Sbjct: 1733 NIQGYKIYYWEADSQNETEKMKVLFLPEPVVR---LKNLTSHTKYLVSISAFNAAGDGPK 1789
Query: 1078 A---TGVFTTLQPGSSIPPYNTEVTETTIVITW-TPAPRIGFKLGVRPSQGGEAPREVTS 1133
+ G PG+ +E+T TT+ ++W PA G G R AP + S
Sbjct: 1790 SDPQQGRTHQAAPGAPSFLAFSEITSTTLNVSWGEPAAANGILQGYRVVYEPLAPVQGVS 1849
Query: 1134 DSGSIVVSG----------LTPGVEYVYTIQ--VLRDGQERDAPIVNKVVTPLSPPTNLH 1181
++ V G LT GV Y + +Q + G E A I SP +
Sbjct: 1850 KVVTVEVRGNWQRWLKVRDLTKGVTYFFRVQARTITYGPELQANITAGPAEG-SPGSPRD 1908
Query: 1182 LEANPDTGVLTVSWERSTTPD--ITGYRITTTPTNGQQGNSLEEVVHADQSSCT--FDNL 1237
+ LT+ W + D TGY I P++ + + + +S T D L
Sbjct: 1909 VLVTKSASELTLQWTEGHSGDTPTTGYVIEARPSDEGLWDMFVKDIPRSATSYTLSLDKL 1968
Query: 1238 SPGLEYNVSVYTVKD 1252
G+ Y V V +
Sbjct: 1969 RQGVTYEFRVVAVNE 1983
Score = 73.6 bits (179), Expect = 2e-12
Identities = 105/399 (26%), Positives = 153/399 (38%), Gaps = 51/399 (12%)
Query: 1689 LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPA------PTDLKFTQVTPTSLSAQW 1742
+ GL P Y V A+++ Q T +P P ++ + T S+ QW
Sbjct: 730 VSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRTNQSIMVQW 789
Query: 1743 TPP-----NVQLTGYRVRVTPKEKTGPMKEINL-APDSSSVVVSGLMVATKYEVSVYALK 1796
PP N L GY +R G ++ N+ +P+ + +V+ L++ T+YE+ V A
Sbjct: 790 QPPPETEHNGVLRGYILRYRLAGLPGEYQQRNITSPEVNYCLVTDLIIWTQYEIQVAAYN 849
Query: 1797 DT--------LTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETIT-----G 1843
+T QGV T +PP+ + TTI W + G
Sbjct: 850 GAGLGVFSRAVTEYTLQGVPT-----APPQNVQTEAVNSTTIQFLWNPPPQQFINGINQG 904
Query: 1844 FQVDAVPANGQTPIQR-TIKPD---VRSYTITGLQPGTDY---KIYLYTLNDNARSSPVV 1896
+++ A PA+ + TI PD V IT L+ T Y + T D S+P +
Sbjct: 905 YKLLAWPADAPEAVTVVTIAPDFHGVHHGHITNLKKFTAYFTSVLCFTTPGDGPPSTPQL 964
Query: 1897 IDASTAIDAPS---NLRFLATTPNSLLVSWQPPRAR---ITGYIIKYEKPGSPPREVVPR 1950
+ T D P +L F SL VSWQ P + ITGY I +E G +
Sbjct: 965 V--WTQEDKPGAVGHLSFTEILDTSLKVSWQEPLEKNGIITGYQISWEVYGRNDSRLTHT 1022
Query: 1951 PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEI 2010
E I GL T YTI V A+ + P L P NL I
Sbjct: 1023 LNSTTHEYKIQGLSSLTTYTIDVAAVTAVGTGLVTSSTISSGVPPDLPGAP-SNLVISNI 1081
Query: 2011 LDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQ 2049
+T+Q PGYD I GQ ++G +
Sbjct: 1082 SPRSATLQ-----FRPGYDGKTSISRWIVEGQVGAIGDE 1115
Score = 33.5 bits (75), Expect = 2.5
Identities = 23/82 (28%), Positives = 40/82 (48%), Gaps = 8/82 (9%)
Query: 1903 IDAPSNLRFLATTPNS-----LLVSWQPP---RARITGYIIKYEKPGSPPREVVPRPRPG 1954
I+ P + + L +PNS +++SW P + I YI++ + SP + + P
Sbjct: 665 IELPHSPQNLLVSPNSSHSHAVVLSWVRPFDGNSPILYYIVELSENNSPWKVHLSNVGPE 724
Query: 1955 VTEATITGLEPGTEYTIYVIAL 1976
+T T++GL P Y V A+
Sbjct: 725 MTGVTVSGLTPARTYQFRVCAV 746
>gi|18860892 protein tyrosine phosphatase, receptor type, D isoform 3
precursor [Homo sapiens]
Length = 1903
Score = 149 bits (377), Expect = 2e-35
Identities = 170/673 (25%), Positives = 286/673 (42%), Gaps = 81/673 (12%)
Query: 1367 SDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPRE-DRVPHSRNSITLTNLTPGTEY 1424
++ TA S T+ W + ++ Y I+H P++ +E D V +R S+ L+P ++Y
Sbjct: 332 TESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEIDGVATTRYSVA--GLSPYSDY 389
Query: 1425 VVSIVALN----GREESPLLIG-QQSTVSDVPRDLEVVAATPTSLLISW---DAPAVTVR 1476
+VA+N G P+L + S PRD++ + T++L+ W + P ++
Sbjct: 390 EFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQ 449
Query: 1477 YYRITY--GETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPI 1534
YR+ Y T + + V S+ T TI L P Y++ V A T GD P SS
Sbjct: 450 GYRVYYTMDPTQHVNNWMKHNVADSQIT-TIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQ 508
Query: 1535 SINYRTEIDKPSQMQVTDVQDNSISVKWL-PSSSPVTGYRVTTTPKNGPGPTKTKTAGPD 1593
I +P + + SI + W P S + Y + K+G + +
Sbjct: 509 VITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANYELVY--KDGEHGEEQRITIEP 566
Query: 1594 QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR-----PKGLAFTDVDVDSI 1648
T ++GL+P Y + A++P G + + + P+ ++ T SI
Sbjct: 567 GTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSI 626
Query: 1649 KIAWESP-----QGQVSRYRVTYSS---PEDGIHELFPAPDGEEDTAE--LQGLRPGSEY 1698
++W+ P G ++ Y + Y++ +D HE+ P DT + L+ L +EY
Sbjct: 627 LVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIP---SDTTKYLLEQLEKWTEY 683
Query: 1699 TVSVVALHDDM----ESQPLIGTQSTAIPA--PTDLKFTQVTPTSLSAQWTPP-----NV 1747
++V A H D+ ES ++ + +P+ P ++ V TS+ W P +
Sbjct: 684 RITVTA-HTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHG 742
Query: 1748 QLTGYRVRVTPKEKTGP-----MKEINLAPDSSSVVVSGLMVATKYEVSVYALK---DTL 1799
Q+ GY+V E P +K++ LA D+ +++SGL T Y ++V A D
Sbjct: 743 QIRGYQVHYVRMENGEPKGQPMLKDVMLA-DAQDMIISGLQPETSYSLTVTAYTTKGDGA 801
Query: 1800 TSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTET---ITGFQV-----DAVPA 1851
S+P +V+T V R + T I W +T + G+++ D P
Sbjct: 802 RSKPK--LVSTTGAVPGKPRLVINHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEPL 859
Query: 1852 NGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPS---- 1907
T ++ + K D +T T + G Y L N +V + S + P+
Sbjct: 860 ---TTLEFSEKED--HFTATDIHKGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQ 914
Query: 1908 NLRFLATTPNSLLVSWQPP-----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITG 1962
NL TT S+ +SWQPP IT Y + Y P + P T T+TG
Sbjct: 915 NLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPADTTMTLTG 974
Query: 1963 LEPGTEYTIYVIA 1975
L+P T Y + V A
Sbjct: 975 LKPDTTYDVKVRA 987
Score = 135 bits (340), Expect = 5e-31
Identities = 201/883 (22%), Positives = 348/883 (39%), Gaps = 117/883 (13%)
Query: 752 VEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAP 811
++ E SEE D+ +Y + + + P Y+ + ++ + I T+ P
Sbjct: 192 LQIEQSEESDQGKYECVATNSAGTRYS--APANLYVRELREVRRVPPRFSIPPTNHEIMP 249
Query: 812 DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ 871
+ T V V+W E + E ++P N + L+D++
Sbjct: 250 GGSVNITCVAVGSPMPYVKWML--------------GAEDLTPEDDMPIGRNVLELNDVR 295
Query: 872 PGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV-EVTDVKVTIMWTPP 930
Y ST VI+ T ++ +P P V E T +T+ W
Sbjct: 296 QSANYTCVAM-------STLGVIEAIAQITVKA--LPKPPGTPVVTESTATSITLTWDSG 346
Query: 931 ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH---GRESK 987
Y + E + + T V GLSP Y F+V AV++ G S+
Sbjct: 347 NPEPVSYYIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSE 406
Query: 988 PLTAQQTTKL--DAPTNLQFVNETDSTVLVRWTPPR---AQITGYRL--TVGLTRR-GQP 1039
P+ Q + + AP ++Q + +T+LV+W P QI GYR+ T+ T+
Sbjct: 407 PVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNW 466
Query: 1040 RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEV- 1098
++NV S + NL P Y+V ++A + P ++ + Q G P N +
Sbjct: 467 MKHNVADSQIT-TIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAE 525
Query: 1099 --TETTIVITWTPAPR----IGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYT 1152
+ET+I+++WTP PR ++L + + GE R S + GL P Y +
Sbjct: 526 PESETSILLSWTP-PRSDTIANYELVYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFR 584
Query: 1153 IQVLRDGQERDAPIVNKVVT-----PLSPPTNLHLEANPDTGVLTVSWERSTTPD----I 1203
+ R Q A P +PP ++ + T +L VSW+ I
Sbjct: 585 LAA-RSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSIL-VSWQPPPVEKQNGII 642
Query: 1204 TGYRITTTPTNGQQGNSLEEV-VHADQSSCTFDNLSPGLEYNVSVYTVKD---DKESVPI 1259
T Y I T +G+ E + + +D + + L EY ++V D ES+ +
Sbjct: 643 TEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSV 702
Query: 1260 SDTIIPAVP--PPTDLRFTNIGPDTMRVTW-APPPSID---LTNFLVRYSPVKNEEDVAE 1313
VP PP + + +++V+W +P P+ + + V Y ++N E +
Sbjct: 703 LIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQ 762
Query: 1314 LSISPSDNA----VVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG------ 1363
+ A ++++ L P T Y ++V++ + + R K L S TG
Sbjct: 763 PMLKDVMLADAQDMIISGLQPETSYSLTVTAYTTKGDGA----RSKPKLVSTTGAVPGKP 818
Query: 1364 -IDFSDITANSFTVHWIAPRAT---ITGYRIRHHPEHFSGRPREDRVP-------HSRNS 1412
+ + N+ + W P T + GYR++ R+D P +
Sbjct: 819 RLVINHTQMNTALIQWHPPVDTFGPLQGYRLKFG--------RKDMEPLTTLEFSEKEDH 870
Query: 1413 ITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISW 1468
T T++ G YV + A N G E + + + P++L T TS+ +SW
Sbjct: 871 FTATDIHKGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSW 930
Query: 1469 DAPAVTVRY-----YRITYGETG-GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT 1522
P + R Y + Y + P+++ VP +T T++GLKP Y + V A T
Sbjct: 931 QPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPAD-TTMTLTGLKPDTTYDVKVRAHT 989
Query: 1523 GRGDSPASSKPISINYRT-EIDK--PSQMQVTDVQDNSISVKW 1562
+G P S S+ +RT +D+ V V S+ + W
Sbjct: 990 SKGPGPYSP---SVQFRTLPVDQVFAKNFHVKAVMKTSVLLSW 1029
Score = 131 bits (330), Expect = 7e-30
Identities = 158/701 (22%), Positives = 294/701 (41%), Gaps = 72/701 (10%)
Query: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS-DTVSGFRVEY 754
++T + ST + T P + VTE TA+S ++W S + + VS + +++
Sbjct: 299 NYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQH 358
Query: 755 ELSEEGDEPQYLDLPSTATS-VNIPDLLPGRKYIVNVYQISEDG----EQSLILSTSQTT 809
+ + E Y ++ AT+ ++ L P Y V ++ G + ++ TS+
Sbjct: 359 K--PKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQA 416
Query: 810 APDAPPDPTVDQVDDTSIVVRWSRPQAP---ITGYRIVYS--PSVEGSSTELNLPETANS 864
AP D + T+I+V+W P+ P I GYR+ Y+ P+ ++ + +
Sbjct: 417 PSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQI 476
Query: 865 VTLSDLQPGVQYNITIYA---VEENQESTPV-VIQQETTGTPRSDTVPSPRDLQFVEVTD 920
T+ +L P Y++ + A + + S+ + VI Q TG P P + + ++
Sbjct: 477 TTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQ--TGVP-----GQPLNFKAEPESE 529
Query: 921 VKVTIMWTPPES-AVTGYRVDVIPVNLPGEHG--QRLPISRNTFAEVTGLSPGVTYYFKV 977
+ + WTPP S + Y + V GEHG QR+ I T + GL P YYF++
Sbjct: 530 TSILLSWTPPRSDTIANYEL----VYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRL 585
Query: 978 FAVSH---GRESKPLTAQ--QTTKLDAPTNLQFVNETDSTVLVRWTPPRAQ-----ITGY 1027
A S G + ++A+ Q+ P ++ + + +++LV W PP + IT Y
Sbjct: 586 AARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEY 645
Query: 1028 --RLTVGLTRRGQPRQYNVGPS-VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV-FT 1083
+ T +P + PS +KY L L+ +EY +++ A P++ V
Sbjct: 646 SIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIR 705
Query: 1084 TLQPGSSIPPYNTE---VTETTIVITW-TPAPR------IGFKLGVRPSQGGEAPRE--- 1130
T + S PP E V T++ ++W +P P G+++ + GE +
Sbjct: 706 TNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPML 765
Query: 1131 ---VTSDSGSIVVSGLTPGVEYVYTIQVLR---DGQERDAPIVNKVVTPLSPPTNLHLEA 1184
+ +D+ +++SGL P Y T+ DG +V+ P +
Sbjct: 766 KDVMLADAQDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVINHT 825
Query: 1185 NPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
+T ++ T + GYR+ + + +LE D + T + +
Sbjct: 826 QMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFR 885
Query: 1245 VSVYTVKDDKESVPISDTIIPAVPP---PTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301
+S E + + + IP P P +L +++++W PP + + +
Sbjct: 886 LSARNKVGFGEEM-VKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITK 944
Query: 1302 YSPVKNEEDV----AELSISPSDNAVVLTNLLPGTEYVVSV 1338
Y+ + + ++ E I P+D + LT L P T Y V V
Sbjct: 945 YTLLYRDINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKV 985
Score = 127 bits (318), Expect = 2e-28
Identities = 187/844 (22%), Positives = 323/844 (38%), Gaps = 89/844 (10%)
Query: 991 AQQTTK-LDAPTNLQFVNETDST-VLVRWTPPRAQITGYRLTVGLTRRGQPRQYNV-GPS 1047
AQ T K L P V E+ +T + + W + Y + + + + G +
Sbjct: 315 AQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEIDGVA 374
Query: 1048 VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT-TLQPGSSIPPYNTE---VTETTI 1103
++Y + L P S+Y +VA+ P + V T T + S P + + ++ TTI
Sbjct: 375 TTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTI 434
Query: 1104 VITWT-PAPRIGFKLGVRPSQGGEAPREVTS-------DSGSIVVSGLTPGVEYVYTIQV 1155
++ W P G G R + + V + DS + L P + Y+++V
Sbjct: 435 LVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVP--QKTYSVKV 492
Query: 1156 LRDGQERDAPIVN--KVVTPLS---PPTNLHLEANPDTGVLTVSWERSTTPDITGYRITT 1210
L D P+ + +V+T P N E +T +L +SW + I Y +
Sbjct: 493 LAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSIL-LSWTPPRSDTIANYELVY 551
Query: 1211 TPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDD---KESVPISDTIIPAV 1267
+G+ G + + +S L P Y + + IS + +
Sbjct: 552 K--DGEHGEE-QRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSK 608
Query: 1268 P--PPTDLRFTNIGPDTMRVTWAPPPSID----LTNFLVRYSPVKNEEDVA-ELSISPSD 1320
P PP D+ T+ ++ V+W PPP +T + ++Y+ V E+D E+ PSD
Sbjct: 609 PSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSD 668
Query: 1321 NA-VVLTNLLPGTEYVVSVSSVYE-----QHESTPLRGRQKTGLDSPTGIDFSDITANSF 1374
+L L TEY ++V++ + + S +R + P ++ + + S
Sbjct: 669 TTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSV 728
Query: 1375 TVHWIAP-----RATITGYRIRHHPEHFSGRPR-----EDRVPHSRNSITLTNLTPGTEY 1424
V W +P I GY++ H+ +G P+ +D + + ++ L P T Y
Sbjct: 729 KVSWRSPVPNKQHGQIRGYQV-HYVRMENGEPKGQPMLKDVMLADAQDMIISGLQPETSY 787
Query: 1425 VVSIVAL----NGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT---VRY 1477
+++ A +G P L+ V PR L + + LI W P T ++
Sbjct: 788 SLTVTAYTTKGDGARSKPKLVSTTGAVPGKPR-LVINHTQMNTALIQWHPPVDTFGPLQG 846
Query: 1478 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISIN 1537
YR+ +G P+ + T + + G Y + A G K ISI
Sbjct: 847 YRLKFGRKD-MEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKEISIP 905
Query: 1538 YRTEIDKPSQMQVTDVQDNSISVKWLPS-----SSPVTGYRVTTTPKNGPGPTKTKTAGP 1592
P + S+ + W P + +T Y + N P + P
Sbjct: 906 EEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVP 965
Query: 1593 DQTEMTIEGLQPTVEYVVSVYAQNPSGES--QPLVQTAVTNIDR--PKGLAFTDVDVDSI 1648
T MT+ GL+P Y V V A G P VQ +D+ K V S+
Sbjct: 966 ADTTMTLTGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAKNFHVKAVMKTSV 1025
Query: 1649 KIAWESPQGQVSR--YRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH 1706
++WE P+ S +++ Y +DG ++ DG + L+P Y+ L
Sbjct: 1026 LLSWEIPENYNSAMPFKILY---DDG--KMVEEVDGRATQKLIVNLKPEKSYS---FVLT 1077
Query: 1707 DDMESQPLIGTQSTAIPAPTDL--KFTQVTPTSLSAQWT------PPNVQLTGYRVRVTP 1758
+ S + + TA AP L K + T+L T P N + GY + + P
Sbjct: 1078 NRGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMITVQLPEVPANENIKGYYIIIVP 1137
Query: 1759 KEKT 1762
+K+
Sbjct: 1138 LKKS 1141
Score = 105 bits (263), Expect = 4e-22
Identities = 156/688 (22%), Positives = 258/688 (37%), Gaps = 93/688 (13%)
Query: 619 TPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNS-YTIKGLKPGVVY 677
T S S + W++ P +S YI++ +PKNS +KE I G + Y++ GL P Y
Sbjct: 332 TESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKE--IDGVATTRYSVAGLSPYSDY 389
Query: 678 EGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFV 737
E +++++ G S PV T T E P S +++++ +
Sbjct: 390 EFRVVAVNNIGR----------GPPSEPVL--TQTSEQAPSS--APRDVQARMLSSTTIL 435
Query: 738 VSWVSASD---TVSGFRVEYELSEEGDEPQYLDLPSTATSV-NIPDLLPGRKYIVNVYQI 793
V W + + G+RV Y + ++ + + I +L+P + Y V V
Sbjct: 436 VQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAF 495
Query: 794 SEDGEQSL---ILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQA-PITGYRIVYSPSV 849
+ G+ L I +QT P P + + +TSI++ W+ P++ I Y +VY
Sbjct: 496 TSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANYELVYKDGE 555
Query: 850 EGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS 909
G + + E S L L+P Y + A + + + + T +S
Sbjct: 556 HGEEQRITI-EPGTSYRLQGLKPNSLYYFRLAA--RSPQGLGASTAEISARTMQSKPSAP 612
Query: 910 PRDLQFVEVTDVKVTIMWTPP-----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEV 964
P+D+ + + + W PP +T Y + V+ GE + E+
Sbjct: 613 PQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVD--GEDDKP--------HEI 662
Query: 965 TGLSPGVTYY----------FKVFAVSH---GRESKPLTAQQTTKLDAPT------NLQF 1005
G+ T Y +++ +H G + L+ T D P+ ++
Sbjct: 663 LGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEA 722
Query: 1006 VNETDSTVLVRWTPP-----RAQITGYRLTVGLTRRGQPRQYNVGPSV-----SKYPLRN 1055
VN T +V V W P QI GY++ G+P+ + V +
Sbjct: 723 VNST--SVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQDMIISG 780
Query: 1056 LQPASEY--TVSLVAIKGNQESPKATGVFTT-LQPGSSIPPYNTEVTETTIVITWTP--- 1109
LQP + Y TV+ KG+ K V TT PG N T +I W P
Sbjct: 781 LQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVIN-HTQMNTALIQWHPPVD 839
Query: 1110 --APRIGFKLGV-RPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD---GQERD 1163
P G++L R E + + + G YV+ + G+E
Sbjct: 840 TFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMV 899
Query: 1164 APIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD----ITGYRITTTPTNGQQGN 1219
I P P NLH E T V +SW+ + IT Y + N
Sbjct: 900 KEISIPEEVPTGFPQNLHSEGTTSTSV-QLSWQPPVLAERNGIITKYTLLYRDINIPLLP 958
Query: 1220 SLEEVVHADQSSCTFDNLSPGLEYNVSV 1247
+ +V AD ++ T L P Y+V V
Sbjct: 959 MEQLIVPAD-TTMTLTGLKPDTTYDVKV 985
Score = 59.7 bits (143), Expect = 3e-08
Identities = 89/403 (22%), Positives = 158/403 (39%), Gaps = 65/403 (16%)
Query: 1798 TLTSRPAQGVVTTLENVS------PPRRARVTDATETTITISWRT-KTETITGFQVDAVP 1850
T + GV+ + ++ PP VT++T T+IT++W + E ++ + + P
Sbjct: 301 TCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKP 360
Query: 1851 ANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNAR---SSPVVIDAS--TAIDA 1905
N + + Y++ GL P +DY+ + +N+ R S PV+ S A
Sbjct: 361 KNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSA 420
Query: 1906 PSNLRFLATTPNSLLVSW---QPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATIT- 1961
P +++ + ++LV W + P +I GY + Y P + V + V ++ IT
Sbjct: 421 PRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTM--DPTQHVNNWMKHNVADSQITT 478
Query: 1962 --GLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQK 2019
L P Y++ V+A + IG Q++T + G + +
Sbjct: 479 IGNLVPQKTYSVKVLAFTS-------IGDGPLSSDIQVIT--QTGVPGQPLNFKAEPESE 529
Query: 2020 TPFV---THPGYDTGNGIQL----------------PGTSGQQPSVGQQMIF-------E 2053
T + T P DT +L PGTS + + ++
Sbjct: 530 TSILLSWTPPRSDTIANYELVYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARS 589
Query: 2054 EHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTI--SWAP------FQDTSEYIISC 2105
G +T +A ++ +P P ++ + S T+I SW P +EY I
Sbjct: 590 PQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKY 649
Query: 2106 HPV-GTDEEPLQ-FRVPGTSTSATLTGLTRGATYNIIVEALKD 2146
V G D++P + +P +T L L + Y I V A D
Sbjct: 650 TAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTD 692
>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform 1
precursor [Homo sapiens]
Length = 1907
Score = 147 bits (371), Expect = 1e-34
Identities = 173/640 (27%), Positives = 262/640 (40%), Gaps = 80/640 (12%)
Query: 1402 REDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPR---DLEVVA 1458
+ED +P RN + L+N+ Y ++ G E+ Q TV +P+ DL V
Sbjct: 274 KEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATA----QVTVKALPKPPIDLVVTE 329
Query: 1459 ATPTSLLISWDAP-AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKPGVDYTI 1516
T TS+ ++WD+ + V YY I Y G P QE V G +T +I GL P +Y
Sbjct: 330 TTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQE--VDGVATTRYSIGGLSPFSEYAF 387
Query: 1517 TVYAVTGRGDSPASSKPISINYRTEIDKPS----QMQVTDVQDNSISVKWLPSSSP---V 1569
V AV G P S ++ RT PS ++Q + +++ V+W P P V
Sbjct: 388 RVLAVNSIGRGPPSE---AVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLV 444
Query: 1570 TGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG-LQPTVEYVVSVYAQNPSGESQPLVQTA 1628
GYRV TP + P D +T G L P + Y + V A G+ P
Sbjct: 445 RGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQ 504
Query: 1629 V-TNIDRPKGLAFTDVDVDS---IKIAWE-SPQGQVSRYRVTY--SSPEDGIHELFPAPD 1681
V T P A +V+S I+++W PQ ++ Y + Y + ED H++ P
Sbjct: 505 VKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPT 564
Query: 1682 GEEDTAELQGLRPGSEYTVSVVALHD--------DMESQPLIGTQSTAIPAPTDLKFTQV 1733
+ L+ L+P + Y + A D +E++ QST P + +
Sbjct: 565 S---SYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEART---AQSTPSAPPQKVMCVSM 618
Query: 1734 TPTSLSAQWTPP-----NVQLTGYRV--RVTPKEKTGPMKEINLAPDSSSVVVSGLMVAT 1786
T++ W PP N +T Y V E G ++ + SS + GL T
Sbjct: 619 GSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWT 678
Query: 1787 KYEVSVYALKDTLTSRPAQGV-VTTLENV--SPPRRARVTDATETTITISWRTKTET--- 1840
+Y V V A D + V V T E+V PPR+ V T + + W+ +
Sbjct: 679 EYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQH 738
Query: 1841 --ITGFQVDAVPANGQTPIQRTIKPDVR--------------SYTITGLQPGTDYKIYLY 1884
I G+QV V P I DV TI+GL P T Y + +
Sbjct: 739 GQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVA 798
Query: 1885 ---TLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR---ARITGYIIKYE 1938
T D ARS P ++ + A+ + T N+ L+ W PP+ + GY ++Y
Sbjct: 799 AYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYC 858
Query: 1939 KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKN 1978
+ + + T+TGL GT Y I+ +A KN
Sbjct: 859 RADEARPNTIDFGKDD-QHFTVTGLHKGTTY-IFRLAAKN 896
Score = 140 bits (354), Expect = 1e-32
Identities = 169/731 (23%), Positives = 290/731 (39%), Gaps = 78/731 (10%)
Query: 1264 IPAVP-PPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNA 1322
+ A+P PP DL T ++ +TW S +T + ++Y E E+ +
Sbjct: 315 VKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVD-GVATTR 373
Query: 1323 VVLTNLLPGTEYVVSVSSVYEQHESTPLRG-RQKTGLDSPTG----IDFSDITANSFTVH 1377
+ L P +EY V +V P R +TG +P+ + ++A++ V
Sbjct: 374 YSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQ 433
Query: 1378 WIAPR---ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT---NLTPGTEYVVSIVAL 1431
W P + GYR+ + P+ S RP H+ ++ LT +L PG Y + ++A
Sbjct: 434 WEPPEEPNGLVRGYRVYYTPD--SRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAF 491
Query: 1432 NGREESP----LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT-VRYYRITYGETG 1486
+ P + + Q V P D + + T + +SW P + Y + Y
Sbjct: 492 TAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAE 551
Query: 1487 GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS 1546
+ T + S+ T+ LKP Y + + R D +I RT PS
Sbjct: 552 DEDQQHKVTFDPT-SSYTLEDLKPDTLYR---FQLAARSDMGVGVFTPTIEARTAQSTPS 607
Query: 1547 ----QMQVTDVQDNSISVKWLPSSSP-----VTGYRVTTTPKNGPGPTKTKTAG--PDQT 1595
++ + ++ V W+P + +T Y V +G + G + +
Sbjct: 608 APPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHS 667
Query: 1596 EMTIEGLQPTVEYVVSVYAQN---PSGESQPLVQTAVTNIDR--PKGLAFTDVDVDSIKI 1650
+ GL+ EY V V A P ES P++ ++ P+ + ++ ++ +
Sbjct: 668 SWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHV 727
Query: 1651 AWESP-----QGQVSRYRVTYSSPEDGIHELFPA------------PDGEED-TAELQGL 1692
W+ P GQ+ Y+VTY E+G P P+ ED + GL
Sbjct: 728 YWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGL 787
Query: 1693 RPGSEYTVSVVALH---DDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNV-- 1747
P + Y+V+V A D S+P I T + A+P + + + QW PP
Sbjct: 788 TPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELP 847
Query: 1748 -QLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQG 1806
+L GYR++ ++ P I+ D V+GL T Y + A +
Sbjct: 848 GELLGYRLQYCRADEARP-NTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEK 906
Query: 1807 VVTTLENVSP--PRRARVTDATETTITISW-----RTKTETITGFQVDAVPANGQTPIQR 1859
+ T E++ P+ VT T +T ++W + I + V N Q +Q
Sbjct: 907 EIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQN 966
Query: 1860 TIKPDVRSYTITGLQPGTDY--KIYLYTLNDNARSSPVVIDASTAIDA--PSNLRFLATT 1915
I D R +T+TGL+P T Y K+ +T + SP + + ++ N R A
Sbjct: 967 -ITTDTR-FTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAM 1024
Query: 1916 PNSLLVSWQPP 1926
S+L+SW+ P
Sbjct: 1025 KTSVLLSWEVP 1035
Score = 127 bits (320), Expect = 1e-28
Identities = 178/740 (24%), Positives = 294/740 (39%), Gaps = 91/740 (12%)
Query: 1308 EEDVAELSISPSDNAVVLTNLLPGTEYV-VSVSSV--YEQHESTPLRGRQKTGLDSPTGI 1364
EE E + N + L+N++ Y V++SS+ E ++ K +D +
Sbjct: 270 EELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTVKALPKPPID----L 325
Query: 1365 DFSDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPRE-DRVPHSRNSITLTNLTPGT 1422
++ TA S T+ W + + +T Y I++ G +E D V +R SI L+P +
Sbjct: 326 VVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVDGVATTRYSIG--GLSPFS 383
Query: 1423 EYVVSIVALNGREESP------LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT-- 1474
EY ++A+N P G+Q+ S PR ++ + +++L+ W+ P
Sbjct: 384 EYAFRVLAVNSIGRGPPSEAVRARTGEQAP-SSPPRRVQARMLSASTMLVQWEPPEEPNG 442
Query: 1475 -VRYYRITYGETGGNSPV---QEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS 1530
VR YR+ Y P + T G +T + L PG+ Y++ V A T GD P S
Sbjct: 443 LVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTT--VGSLLPGITYSLRVLAFTAVGDGPPS 500
Query: 1531 SKPISINYRTEIDKPSQ---MQVTDVQDNSISVKWL-PSSSPVTGYRVTTTPKNGPGPTK 1586
+I +T+ P+Q Q D I + WL P + Y +
Sbjct: 501 P---TIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQH 557
Query: 1587 TKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES--QPLVQTAV---TNIDRPKGLAFT 1641
T P + T+E L+P Y + A++ G P ++ T P+ +
Sbjct: 558 KVTFDPTSS-YTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCV 616
Query: 1642 DVDVDSIKIAWESP-----QGQVSRYRVTYSSP--EDGIHELFPAPDGEEDTAELQGLRP 1694
+ +++++W P G +++Y V Y + ED + E + +L GL
Sbjct: 617 SMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEK 676
Query: 1695 GSEYTVSVVALHDDM----ESQPLIGTQSTAIPA--PTDLKFTQVTPTSLSAQWTPP--- 1745
+EY V V A H D+ ES P++ +P+ P ++ + T++ W P
Sbjct: 677 WTEYRVWVRA-HTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPS 735
Query: 1746 --NVQLTGYRVRVTPKEKTGP----------MKEINLAPDSSS---VVVSGLMVATKYEV 1790
+ Q+ GY+V E P + E P+ S +SGL T Y V
Sbjct: 736 KQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSV 795
Query: 1791 SVYALK---DTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTET---ITGF 1844
+V A D S+P +VTT V ++ T + W E + G+
Sbjct: 796 TVAAYTTKGDGARSKPK--IVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGY 853
Query: 1845 QVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAID 1904
++ A+ P D + +T+TGL GT Y L N + T D
Sbjct: 854 RLQYCRADEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPED 913
Query: 1905 APS----NLRFLATTPNSLLVSWQPP-----RARITGYIIKYEKPGSPPREVVPRPRPGV 1955
PS NL T ++ ++W PP RI Y + + S + +
Sbjct: 914 LPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINS---QQELQNITTD 970
Query: 1956 TEATITGLEPGTEYTIYVIA 1975
T T+TGL+P T Y I V A
Sbjct: 971 TRFTLTGLKPDTTYDIKVRA 990
Score = 118 bits (295), Expect = 8e-26
Identities = 192/823 (23%), Positives = 311/823 (37%), Gaps = 94/823 (11%)
Query: 862 ANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQ----ETTGTPRSDTVPSPR-DLQFV 916
A +T D P + + + V + T V I E T +P P DL
Sbjct: 269 AEELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVT 328
Query: 917 EVTDVKVTIMWTPPESA-VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYF 975
E T VT+ W S VT Y + G Q + T + GLSP Y F
Sbjct: 329 ETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPF-QEVDGVATTRYSIGGLSPFSEYAF 387
Query: 976 KVFAVS---HGRESKPLTAQ--QTTKLDAPTNLQFVNETDSTVLVRWTP---PRAQITGY 1027
+V AV+ G S+ + A+ + P +Q + ST+LV+W P P + GY
Sbjct: 388 RVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGY 447
Query: 1028 RLTVGLTRRGQP---RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTT 1084
R+ R P ++N + + +L P Y++ ++A + P + +
Sbjct: 448 RVYYTPDSRRPPNAWHKHNTDAGLLT-TVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVK 506
Query: 1085 LQPGSSIPP--YNTEV-TETTIVITWTPAPR---IGFKLGVRPSQGGEAPREVTSD-SGS 1137
Q G P + EV ++T I ++W P+ I ++L ++ + +VT D + S
Sbjct: 507 TQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPTSS 566
Query: 1138 IVVSGLTPGVEYVYTIQVLRD-GQERDAPIVNKVV---TPLSPPTNLHLEANPDTGVLTV 1193
+ L P Y + + D G P + TP +PP + + T V V
Sbjct: 567 YTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTV-RV 625
Query: 1194 SW----ERSTTPDITGYRITTTPTNGQ-QGNSLEEVVHADQSSCTFDNLSPGLEYNVSVY 1248
SW S IT Y + +G+ +G + + + + SS L EY V V
Sbjct: 626 SWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVR 685
Query: 1249 TVKD---DKESVPI---SDTIIPAVPPPTDLRFTNIGPDTMRVTW-APPPS--------- 1292
D ES P+ +D +P+ PP + + + V W P PS
Sbjct: 686 AHTDVGPGPESSPVLVRTDEDVPS-GPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGY 744
Query: 1293 ----IDLTNFLVRYSPVKNEEDVAELSISP---SDNAVVLTNLLPGTEYVVSVSSVYEQH 1345
+ L N R P+ + +AE P D ++ L P T Y V+V++ +
Sbjct: 745 QVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKG 804
Query: 1346 ESTPLRGRQKTGLDSPTG-------IDFSDITANSFTVHWIAPR---ATITGYRIRHHPE 1395
+ R K + + TG + S N+ + W P+ + GYR+++
Sbjct: 805 DG----ARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRA 860
Query: 1396 HFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTVSDVP 1451
RP T+T L GT Y+ + A N G E + + S P
Sbjct: 861 D-EARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFP 919
Query: 1452 RDLEVVAATPTSLLISWDAPAVTVR-----YYRITYGETGGNSPVQEFTVPGSKSTATIS 1506
++L V T ++ ++WD P + R Y + + + +Q T + + T++
Sbjct: 920 QNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNIT---TDTRFTLT 976
Query: 1507 GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW-LPS 1565
GLKP Y I V A T +G P S S E +V S+ + W +P
Sbjct: 977 GLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPD 1036
Query: 1566 SSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEY 1608
S Y+ K + G ++ I LQP EY
Sbjct: 1037 S-----YKSAVPFKILYNGQSVEVDGHSMRKL-IADLQPNTEY 1073
Score = 108 bits (270), Expect = 6e-23
Identities = 172/783 (21%), Positives = 290/783 (37%), Gaps = 91/783 (11%)
Query: 990 TAQQTTKL--DAPTNLQFVNETDSTVLVRWTPPRAQ-ITGYRLTVGLTRRGQPRQYNVGP 1046
TAQ T K P +L T ++V + W ++ +T Y + P Q G
Sbjct: 310 TAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVDGV 369
Query: 1047 SVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT-TLQPGSSIPPYNTE---VTETT 1102
+ ++Y + L P SEY ++A+ P + V T + S PP + ++ +T
Sbjct: 370 ATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSAST 429
Query: 1103 IVITWTPAPRI-----GFKLGVRPS--QGGEAPREVTSDSGSIVVSG-LTPGVEY---VY 1151
+++ W P G+++ P + A + +D+G + G L PG+ Y V
Sbjct: 430 MLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVL 489
Query: 1152 TIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTT 1211
+ DG V + P + E DT + +SW I Y +
Sbjct: 490 AFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRI-QLSWLLPPQERIIMYELVYW 548
Query: 1212 PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV---PISDTIIPAVP 1268
+ + +V SS T ++L P Y + D V I + P
Sbjct: 549 AAEDE--DQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTP 606
Query: 1269 --PPTDLRFTNIGPDTMRVTWAPPPSID----LTNFLVRYSPVKNEEDVAEL--SISPSD 1320
PP + ++G T+RV+W PPP+ +T + V Y V E+ + IS
Sbjct: 607 SAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREH 666
Query: 1321 NAVVLTNLLPGTEYVVSV---SSVYEQHESTPLRGRQKTGLDS--PTGIDFSDITANSFT 1375
++ L L TEY V V + V ES+P+ R + S P ++ + + +
Sbjct: 667 SSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVH 726
Query: 1376 VHWIAP-----RATITGYRIRHHPEHFSGRPR-------------EDRVPHSRN-SITLT 1416
V+W P I GY++ + +G PR + R S + T++
Sbjct: 727 VYWKLPVPSKQHGQIRGYQVT-YVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTIS 785
Query: 1417 NLTPGTEYVVSIVAL----NGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA 1472
LTP T Y V++ A +G P ++ V P + A T+LL W P
Sbjct: 786 GLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALL-QWHPPK 844
Query: 1473 V---TVRYYRITYGETGGNSPVQEFTVPGSKSTA--TISGLKPGVDYTITVYAVTGRGDS 1527
+ YR+ Y P T+ K T++GL G Y + A G
Sbjct: 845 ELPGELLGYRLQYCRADEARP---NTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLG 901
Query: 1528 PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP-----SSSPVTGYRVTTTPKNGP 1582
K I P + VT + ++ + W P + + Y V N
Sbjct: 902 EEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQ 961
Query: 1583 GPTKTKTAGPDQTEMTIEGLQPTVEYVVSV--YAQNPSGESQPLVQTAVTNIDR--PKGL 1638
+ T T T+ GL+P Y + V + SG P +Q+ +++ K
Sbjct: 962 QELQNITT---DTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNF 1018
Query: 1639 AFTDVDVDSIKIAWESPQGQVSR--YRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGS 1696
S+ ++WE P S +++ Y+ + DG + L+P +
Sbjct: 1019 RVAAAMKTSVLLSWEVPDSYKSAVPFKILYNGQSVEV-------DGHSMRKLIADLQPNT 1071
Query: 1697 EYT 1699
EY+
Sbjct: 1072 EYS 1074
Score = 103 bits (256), Expect = 3e-21
Identities = 197/902 (21%), Positives = 354/902 (39%), Gaps = 119/902 (13%)
Query: 1087 PGSSIPPYNTEV-----TETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVS 1141
P SIPP + EV T V P P + + +G + E+ + +S
Sbjct: 232 PRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKED---EMPVGRNVLELS 288
Query: 1142 GLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTP 1201
+ Y E A + K + PP +L + T V T++W+ +
Sbjct: 289 NVVRSANYTCVAISSLGMIEATAQVTVKALP--KPPIDLVVTETTATSV-TLTWDSGNSE 345
Query: 1202 DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD-----DKES 1256
+T Y I G +G +EV + + LSP EY V V E+
Sbjct: 346 PVTYYGIQYRAA-GTEG-PFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEA 403
Query: 1257 VPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP--PSIDLTNFLVRYSPVKNEEDVAEL 1314
V PP ++ + TM V W PP P+ + + V Y+P A
Sbjct: 404 VRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWH 463
Query: 1315 SISPSDNAVVLT--NLLPGTEY---VVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDI 1369
+ +D ++ T +LLPG Y V++ ++V + S ++ + + G+ + +++
Sbjct: 464 KHN-TDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEV 522
Query: 1370 TANS-FTVHWIAP-RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVS 1427
+++ + W+ P + I Y + + + + + +S TL +L P T Y
Sbjct: 523 ESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPT-SSYTLEDLKPDTLYRFQ 581
Query: 1428 IVALNGREE---SPLLIGQ--QSTVSDVPRDLEVVAATPTSLLISWDAPAVTVR-----Y 1477
+ A + +P + + QST S P+ + V+ T++ +SW P R
Sbjct: 582 LAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQ 641
Query: 1478 YRITY----GETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKP 1533
Y + Y GE G V + S+ + GL+ +Y + V A T G P SS P
Sbjct: 642 YSVAYEAVDGEDRGRHVVDG--ISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESS-P 698
Query: 1534 ISINYRTEIDKPS----QMQVTDVQDNSISVKW---LPSSS--PVTGYRVTTT------P 1578
+ + RT+ D PS +++V + ++ V W +PS + GY+VT P
Sbjct: 699 VLV--RTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEP 756
Query: 1579 KNGP-------GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE---SQPLVQTA 1628
+ P + + + E TI GL P Y V+V A G+ S+P + T
Sbjct: 757 RGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTT 816
Query: 1629 VTNIDRPKGLAFTDVDVDSIKIAWESPQ---GQVSRYRVTYSSPEDGIHELFPAPDGEED 1685
+ + + +++ + W P+ G++ YR+ Y ++ G++D
Sbjct: 817 TGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRADEARPNTIDF--GKDD 874
Query: 1686 TA-ELQGLRPGSEYTVSVVA-----LHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLS 1739
+ GL G+ Y + A L ++ E + + + P +L T +T ++
Sbjct: 875 QHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKE-IRTPEDLPSGFPQNLHVTGLTTSTTE 933
Query: 1740 AQWTPP-----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYA 1794
W PP N ++ Y V +E+ + ++GL T Y++ V A
Sbjct: 934 LAWDPPVLAERNGRIISYTVVF---RDINSQQELQNITTDTRFTLTGLKPDTTYDIKVRA 990
Query: 1795 LKDTLTSRPAQGVVTTLENVSPP------RRARVTDATETTITISWRTKTETITGFQVDA 1848
TS+ + + ++++ + P + RV A +T++ +SW + A
Sbjct: 991 W----TSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWE-----VPDSYKSA 1041
Query: 1849 VPA----NGQTPIQRTIKPDVRSYT--ITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA 1902
VP NGQ+ ++ D S I LQP T+Y L +A ++ TA
Sbjct: 1042 VPFKILYNGQS-----VEVDGHSMRKLIADLQPNTEYSFVLMNRGSSAGGLQHLVSIRTA 1096
Query: 1903 ID 1904
D
Sbjct: 1097 PD 1098
Score = 82.8 bits (203), Expect = 4e-15
Identities = 126/575 (21%), Positives = 224/575 (38%), Gaps = 76/575 (13%)
Query: 628 IQWNAPQPSHISKY-ILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQ 686
+ W P I Y ++ W ++ + K P +SYT++ LKP +Y QL +
Sbjct: 530 LSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDP--TSSYTLEDLKPDTLYRFQLAARSD 587
Query: 687 YGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV----- 741
G T T+ STP + P ++ S T + VSWV
Sbjct: 588 MGVGVFTPTIEARTAQSTP---------SAPPQKVMCVSMGSTTVR-----VSWVPPPAD 633
Query: 742 SASDTVSGFRVEYELSEEGDEPQYL--DLPSTATSVNIPDLLPGRKYIVNVYQISEDG-- 797
S + ++ + V YE + D +++ + +S ++ L +Y V V ++ G
Sbjct: 634 SRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPG 693
Query: 798 -EQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVRW-----SRPQAPITGYRIVYSPSVE 850
E S +L + P PP V+ ++ T++ V W S+ I GY++ Y
Sbjct: 694 PESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLEN 753
Query: 851 GSSTELNL------------PETAN--SVTLSDLQPGVQYNITIYAVE---ENQESTPVV 893
G L + PE + T+S L P Y++T+ A + S P +
Sbjct: 754 GEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDGARSKPKI 813
Query: 894 IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM-WTPPE---SAVTGYRVDVIPVNLPGE 949
+ TTG VP R + T + ++ W PP+ + GYR+ +
Sbjct: 814 V--TTTG-----AVPG-RPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRADEARP 865
Query: 950 HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT----NLQF 1005
+ F VTGL G TY F++ A + + + T D P+ NL
Sbjct: 866 NTIDFGKDDQHFT-VTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHV 924
Query: 1006 VNETDSTVLVRWTPP-RAQITGYRLTVGLTRR---GQPRQYNVGPSVSKYPLRNLQPASE 1061
T ST + W PP A+ G ++ + R Q N+ + +++ L L+P +
Sbjct: 925 TGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNI-TTDTRFTLTGLKPDTT 983
Query: 1062 YTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVT---ETTIVITWTPAPRIGFKLG 1118
Y + + A P + + + P + N V +T+++++W +
Sbjct: 984 YDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVP 1043
Query: 1119 VRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTI 1153
+ G++ EV S +++ L P EY + +
Sbjct: 1044 FKILYNGQSV-EVDGHSMRKLIADLQPNTEYSFVL 1077
>gi|20665034 tenascin XB isoform 2 [Homo sapiens]
Length = 673
Score = 147 bits (370), Expect = 2e-34
Identities = 109/439 (24%), Positives = 191/439 (43%), Gaps = 30/439 (6%)
Query: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619
+ W + P + V NG P G DQ+++ I GL+P+ Y +Y +
Sbjct: 3 LSWSVAQGPFDSFVVQYEDTNGQ-PQALLVDG-DQSKILISGLEPSTPYRFLLYGLHEGK 60
Query: 1620 ESQPLVQTAVTNI---------DRPK--GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSS 1668
PL T + RP+ L+ TDV S+++ WE+P G + + +
Sbjct: 61 RLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGV 120
Query: 1669 PEDGIHELFPAP--------DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST 1720
P E P P G +A L+ LR G+ Y++++ L ++ + GT T
Sbjct: 121 PSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTART 180
Query: 1721 AIP---APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV 1777
P +P DL+F+++ TS W PP + ++V + P + + + + +
Sbjct: 181 LSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEP-QSVQVDGQARTQ 239
Query: 1778 VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTK 1837
+ GL+ +YEV+V +++ S P G +TT+ + P + R + TE + W+
Sbjct: 240 KLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPD--GPTQLRALNLTEGFAVLHWKPP 297
Query: 1838 TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1897
+ + V V A G P+Q Y + L T+Y + L +SP I
Sbjct: 298 QNPVDTYDVQ-VTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASI 356
Query: 1898 DASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTE 1957
+T ++AP +L TP + L++W P R GY++ + PG +E++ G+T
Sbjct: 357 TFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEIL--LPGGITS 414
Query: 1958 ATITGLEPGTEYTIYVIAL 1976
+ GL P T Y + A+
Sbjct: 415 HQLLGLFPSTSYNARLQAM 433
Score = 119 bits (299), Expect = 3e-26
Identities = 108/440 (24%), Positives = 181/440 (41%), Gaps = 36/440 (8%)
Query: 1191 LTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
+ +SW + P + + TNGQ L V DQS L P Y +Y +
Sbjct: 1 MRLSWSVAQGP-FDSFVVQYEDTNGQPQALL---VDGDQSKILISGLEPSTPYRFLLYGL 56
Query: 1251 KDDKESVPIS-----------DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFL 1299
+ K P+S T + P + L T++ ++R+ W PP +FL
Sbjct: 57 HEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGA-FDSFL 115
Query: 1300 VRY---SPVKNEEDVA-----ELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR 1351
+R+ SP E EL + + ++ VL +L GT Y +++ + H++ ++
Sbjct: 116 LRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQ 175
Query: 1352 GRQKT---GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH 1408
G +T L+SP + FS+I S V+W+ P + +++ + G P+ +V
Sbjct: 176 GTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLAD-GGEPQSVQVDG 234
Query: 1409 SRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISW 1468
+ L L PG Y V++V++ G EES L G +TV D P L + T ++ W
Sbjct: 235 QARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHW 294
Query: 1469 DAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSP 1528
P V Y + T +P + PGS + L +YT TV + G P
Sbjct: 295 KPPQNPVDTYDVQV--TAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRG----P 348
Query: 1529 ASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTK 1588
+ P SI + T ++ P ++ +V + + W GY ++ G
Sbjct: 349 NLTSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILL 408
Query: 1589 TAGPDQTEMTIEGLQPTVEY 1608
G T + GL P+ Y
Sbjct: 409 PGG--ITSHQLLGLFPSTSY 426
Score = 117 bits (294), Expect = 1e-25
Identities = 115/480 (23%), Positives = 197/480 (41%), Gaps = 57/480 (11%)
Query: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
+ W+ Q +++++ N G+ + + G + I GL+P Y L Y
Sbjct: 3 LSWSVAQ-GPFDSFVVQYEDTN--GQPQALLVDGDQSKILISGLEPSTPYRFLL-----Y 54
Query: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
G E R + +T + G+T+ S + SVT++T SS ++W +
Sbjct: 55 GLHEGKRLGPLSAEGTTGLAP---AGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAF 111
Query: 748 SGFRVEYELSEEGD-EP-------QYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQ 799
F + + + EP + L +P T S + DL G Y + +Y + +
Sbjct: 112 DSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKA 171
Query: 800 SLILSTSQTTAP--DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELN 857
I T++T +P ++P D ++ +TS V W P + +++ Y + G +
Sbjct: 172 DSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQ 231
Query: 858 LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVP-SPRDLQFV 916
+ A + L L PG +Y +T+ +V +ES P+ T TVP P L+ +
Sbjct: 232 VDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPL--------TGFLTTVPDGPTQLRAL 283
Query: 917 EVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQR-----------LPISRNTFAEVT 965
+T+ + W PP++ V Y V V P + L + N A V
Sbjct: 284 NLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVR 343
Query: 966 GL-SPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQI 1024
GL P +T P + TT L+AP +L+ T T L+ WT P +
Sbjct: 344 GLRGPNLT--------------SPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRP 389
Query: 1025 TGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTT 1084
GY L+ T GQ ++ + ++ + L L P++ Y L A+ G P + FTT
Sbjct: 390 AGYLLSFH-TPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTT 448
Score = 106 bits (264), Expect = 3e-22
Identities = 83/358 (23%), Positives = 143/358 (39%), Gaps = 26/358 (7%)
Query: 1648 IKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD 1707
++++W QG + V Y L DG++ + GL P + Y + LH+
Sbjct: 1 MRLSWSVAQGPFDSFVVQYEDTNGQPQALLV--DGDQSKILISGLEPSTPYRFLLYGLHE 58
Query: 1708 DMESQPLIGTQSTAI-----------PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR- 1755
PL +T + P + L T VT +SL W P + +R
Sbjct: 59 GKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRF 118
Query: 1756 -------VTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVV 1808
+ P + +E+ + S V+ L T Y +++Y L+ + QG
Sbjct: 119 GVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTA 178
Query: 1809 TTLENV-SPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRS 1867
TL V PR + ++ ET+ ++W F+V A+G P + R+
Sbjct: 179 RTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQART 238
Query: 1868 YTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR 1927
+ GL PG Y++ + ++ S P+ +T D P+ LR L T ++ W+PP+
Sbjct: 239 QKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQ 298
Query: 1928 ARITGYIIKYEKPGSPPREVVPRPRPG-VTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
+ Y ++ PG+PP + PG + + L T YT V L+ + P
Sbjct: 299 NPVDTYDVQVTAPGAPPLQA---ETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSP 353
Score = 96.7 bits (239), Expect = 2e-19
Identities = 108/467 (23%), Positives = 188/467 (40%), Gaps = 38/467 (8%)
Query: 831 WSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQEST 890
WS Q P + + Y + G L + + + +S L+P Y +Y + E +
Sbjct: 5 WSVAQGPFDSFVVQYEDT-NGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLG 63
Query: 891 PVVIQQETTGTPRSDTVPSPR----DLQFVEVTDVKVTIMWTPPESAVTGY--RVDVIPV 944
P+ + T P T R L +VT + + W P A + R V
Sbjct: 64 PLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSP 123
Query: 945 NLPGEHGQRL-------PISRNTFAEVTGLSPGVTYYFKVFAVS--HGRESKPLTAQQTT 995
+ H + L P +R++ A + L G Y ++ + H +S TA+ +
Sbjct: 124 STLEPHPRPLLQRELMVPGTRHS-AVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLS 182
Query: 996 K-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLR 1054
L++P +LQF +++ V W PP ++ ++++ L G+P+ V L+
Sbjct: 183 PVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQ 242
Query: 1055 NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG-SSIPPYNTEVTETTIVITWTPAPRI 1113
L P + Y V++V+++G +ES TG TT+ G + + N +TE V+ W P
Sbjct: 243 GLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALN--LTEGFAVLHWKPPQNP 300
Query: 1114 GFKLGVRPSQGGEAPREVTSDSGSI--VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVV 1171
V+ + G P + + ++ + L Y T++ LR G +P
Sbjct: 301 VDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLR-GPNLTSPASITFT 359
Query: 1172 TPLSPPTNLHL-EANPDTGVLTVSWERSTTPDI--TGYRITTTPTNGQQGNSLEEVVHAD 1228
T L P +L E P T +LT W T P + GY ++ GQ + E ++
Sbjct: 360 TGLEAPRDLEAKEVTPRTALLT--W---TEPPVRPAGYLLSFHTPGGQ---NQEILLPGG 411
Query: 1229 QSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPA---VPPPTD 1272
+S L P YN + + P+S + +P P D
Sbjct: 412 ITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRD 458
Score = 73.2 bits (178), Expect = 3e-12
Identities = 103/425 (24%), Positives = 174/425 (40%), Gaps = 44/425 (10%)
Query: 1759 KEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTT-------L 1811
++ G + + + D S +++SGL +T Y +Y L + P TT
Sbjct: 20 EDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQT 79
Query: 1812 ENVSPPRRAR--VTDATETTITISWRTKTETITGFQVD-AVPA------NGQTPIQRTIK 1862
S PR ++ VTD T +++ ++W F + VP+ + + +QR +
Sbjct: 80 SEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQRELM 139
Query: 1863 -PDVR-SYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST---AIDAPSNLRFLATTPN 1917
P R S + L+ GT Y + LY L ++ + A T +++P +L+F
Sbjct: 140 VPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEIRET 199
Query: 1918 SLLVSWQPPRARITGYIIKYE-KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL 1976
S V+W PP +R + + Y+ G P+ V + + + GL PG Y + V+++
Sbjct: 200 SAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQK--LQGLIPGARYEVTVVSV 257
Query: 1977 KNNQKSEPLIGRKKT--DELPQL----VTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDT 2030
+ ++SEPL G T D QL +T LH + T VT PG
Sbjct: 258 RGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQ--VTAPGAPP 315
Query: 2031 GNGIQLPGTSGQQP----SVGQQMIFEEHGFR--RTTPPTTATPIRHRPRPYPPNVGQEA 2084
+ PG++ P + G R T P + T P +
Sbjct: 316 LQA-ETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLEAPRDLEAKEVT 374
Query: 2085 LSQTTISWA-PFQDTSEYIISCH-PVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVE 2142
++W P + Y++S H P G ++E L +PG TS L GL +YN ++
Sbjct: 375 PRTALLTWTEPPVRPAGYLLSFHTPGGQNQEIL---LPGGITSHQLLGLFPSTSYNARLQ 431
Query: 2143 ALKDQ 2147
A+ Q
Sbjct: 432 AMWGQ 436
Score = 63.9 bits (154), Expect = 2e-09
Identities = 83/357 (23%), Positives = 134/357 (37%), Gaps = 56/357 (15%)
Query: 1832 ISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNAR 1891
+SW F V NGQ P + D I+GL+P T Y+ LY L++ R
Sbjct: 3 LSWSVAQGPFDSFVVQYEDTNGQ-PQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKR 61
Query: 1892 SSPVVIDASTAIDAP------------SNLRFLATTPNSLLVSWQPPRARITGYIIKYEK 1939
P+ + +T + AP S L T +SL ++W+ P +++++
Sbjct: 62 LGPLSAEGTTGL-APAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGV 120
Query: 1940 PGSPPREVVPRPR-------PGVTE-ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT 1991
P E PRP PG A + L GT Y++ + L+ K++ + G +T
Sbjct: 121 PSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTART 180
Query: 1992 DELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHP-----GYDTGNG-----IQLPGTSG 2041
L ++ P +L EI + + V P + Y +G +Q+ G +
Sbjct: 181 --LSPVLESPR-DLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQAR 237
Query: 2042 QQPSVG-------QQMIFEEHGFRRTTPPTT-ATPIRHRPRPYPPNVGQEALSQT----T 2089
Q G + + GF + P T T + P AL+ T
Sbjct: 238 TQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQL------RALNLTEGFAV 291
Query: 2090 ISWAPFQDTSE-YIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALK 2145
+ W P Q+ + Y + G PLQ PG++ L L Y V L+
Sbjct: 292 LHWKPPQNPVDTYDVQVTAPGAP--PLQAETPGSAVDYPLHDLVLHTNYTATVRGLR 346
>gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens]
Length = 610
Score = 146 bits (368), Expect = 3e-34
Identities = 70/178 (39%), Positives = 97/178 (54%), Gaps = 16/178 (8%)
Query: 344 ETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTD 403
E V + GN++GE C PF +NG+ + SCT GR DG LWCSTT N+E+D KY FC
Sbjct: 167 EGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPH 226
Query: 404 HTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPM 463
+ T GGN+ G C FPF + +Y CT+EGR D +WCGTT++YD D+K+GFCP
Sbjct: 227 EALF--TMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE 284
Query: 464 AAHEEICTTNEGV-----MYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRD 516
A + +EG +G++++ CT G G+ C + D
Sbjct: 285 TAMSTVGGNSEGAPCVFPFTFLGNKYES---------CTSAGRSDGKMWCATTANYDD 333
Score = 145 bits (365), Expect = 6e-34
Identities = 77/171 (45%), Positives = 97/171 (56%), Gaps = 18/171 (10%)
Query: 305 YGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPF 364
Y C TD+G S G W T N + G C A+ T GGN+ G+PC PF
Sbjct: 194 YNSC-TDTG--RSDGFLWCSTTYNFEKD----GKYGFCPHEALF-TMGGNAEGQPCKFPF 245
Query: 365 TYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPF 424
+ G ++ SCTTEGR DG+ WC TT +Y++D+KY FC + + T GGNS GA C FPF
Sbjct: 246 RFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE--TAMSTVGGNSEGAPCVFPF 303
Query: 425 LYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCP--------MAAHE 467
+ + Y CTS GR D WC TT NYD D+K+GFCP +AAHE
Sbjct: 304 TFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHE 354
>gi|11342666 matrix metalloproteinase 2 isoform a preproprotein
[Homo sapiens]
Length = 660
Score = 146 bits (368), Expect = 3e-34
Identities = 70/178 (39%), Positives = 97/178 (54%), Gaps = 16/178 (8%)
Query: 344 ETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTD 403
E V + GN++GE C PF +NG+ + SCT GR DG LWCSTT N+E+D KY FC
Sbjct: 217 EGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPH 276
Query: 404 HTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPM 463
+ T GGN+ G C FPF + +Y CT+EGR D +WCGTT++YD D+K+GFCP
Sbjct: 277 EALF--TMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE 334
Query: 464 AAHEEICTTNEGV-----MYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRD 516
A + +EG +G++++ CT G G+ C + D
Sbjct: 335 TAMSTVGGNSEGAPCVFPFTFLGNKYES---------CTSAGRSDGKMWCATTANYDD 383
Score = 145 bits (365), Expect = 6e-34
Identities = 77/171 (45%), Positives = 97/171 (56%), Gaps = 18/171 (10%)
Query: 305 YGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPF 364
Y C TD+G S G W T N + G C A+ T GGN+ G+PC PF
Sbjct: 244 YNSC-TDTG--RSDGFLWCSTTYNFEKD----GKYGFCPHEALF-TMGGNAEGQPCKFPF 295
Query: 365 TYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPF 424
+ G ++ SCTTEGR DG+ WC TT +Y++D+KY FC + + T GGNS GA C FPF
Sbjct: 296 RFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE--TAMSTVGGNSEGAPCVFPF 353
Query: 425 LYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCP--------MAAHE 467
+ + Y CTS GR D WC TT NYD D+K+GFCP +AAHE
Sbjct: 354 TFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHE 404
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.132 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 108,033,050
Number of Sequences: 37866
Number of extensions: 5771663
Number of successful extensions: 23694
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 106
Number of HSP's successfully gapped in prelim test: 230
Number of HSP's that attempted gapping in prelim test: 11603
Number of HSP's gapped (non-prelim): 3619
length of query: 2355
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2236
effective length of database: 13,741,464
effective search space: 30725913504
effective search space used: 30725913504
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.