Guide to the Human Genome
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Search of human proteins with 169234663

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169234663 tumor protein p63 isoform 5 [Homo sapiens]
         (461 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169234663 tumor protein p63 isoform 5 [Homo sapiens]               948   0.0  
gi|169234661 tumor protein p63 isoform 4 [Homo sapiens]               937   0.0  
gi|169234657 tumor protein p63 isoform 2 [Homo sapiens]               920   0.0  
gi|31543818 tumor protein p63 isoform 1 [Homo sapiens]                909   0.0  
gi|169234665 tumor protein p63 isoform 6 [Homo sapiens]               726   0.0  
gi|169234659 tumor protein p63 isoform 3 [Homo sapiens]               699   0.0  
gi|187829017 tumor protein p73 isoform c [Homo sapiens]               546   e-155
gi|187828902 tumor protein p73 isoform b [Homo sapiens]               540   e-154
gi|4885645 tumor protein p73 isoform a [Homo sapiens]                 540   e-154
gi|187829052 tumor protein p73 isoform d [Homo sapiens]               481   e-136
gi|187830777 tumor protein p53 isoform a [Homo sapiens]               273   3e-73
gi|120407068 tumor protein p53 isoform a [Homo sapiens]               273   3e-73
gi|187830855 tumor protein p53 isoform b [Homo sapiens]               253   3e-67
gi|187830823 tumor protein p53 isoform c [Homo sapiens]               253   3e-67
gi|187830894 tumor protein p53 isoform d [Homo sapiens]               236   2e-62
gi|187830909 tumor protein p53 isoform f [Homo sapiens]               216   3e-56
gi|187830901 tumor protein p53 isoform e [Homo sapiens]               216   3e-56
gi|7662302 TBK1 binding protein 1 [Homo sapiens]                       42   0.001
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s...    40   0.003
gi|56549694 enabled homolog isoform a [Homo sapiens]                   40   0.006
gi|39930375 enabled homolog isoform b [Homo sapiens]                   40   0.006
gi|55953100 tubby like protein 4 isoform 1 [Homo sapiens]              39   0.010
gi|157168329 formin 1 [Homo sapiens]                                   38   0.017
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]              38   0.017
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]       37   0.029
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]       37   0.029
gi|48255900 SWI/SNF-related matrix-associated actin-dependent re...    37   0.038
gi|48255898 SWI/SNF-related matrix-associated actin-dependent re...    37   0.038
gi|32307124 nuclear receptor coactivator 3 isoform b [Homo sapiens]    36   0.084
gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo sapi...    35   0.11 

>gi|169234663 tumor protein p63 isoform 5 [Homo sapiens]
          Length = 461

 Score =  948 bits (2450), Expect = 0.0
 Identities = 461/461 (100%), Positives = 461/461 (100%)

Query: 1   MLYLENNAQTQFSEPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSS 60
           MLYLENNAQTQFSEPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSS
Sbjct: 1   MLYLENNAQTQFSEPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSS 60

Query: 61  TFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIK 120
           TFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIK
Sbjct: 61  TFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIK 120

Query: 121 VMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQ 180
           VMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQ
Sbjct: 121 VMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQ 180

Query: 181 YVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQV 240
           YVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQV
Sbjct: 181 YVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQV 240

Query: 241 LGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRR 300
           LGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRR
Sbjct: 241 LGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRR 300

Query: 301 SPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSIQ 360
           SPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSIQ
Sbjct: 301 SPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSIQ 360

Query: 361 SPSSYGNSSPPLNKMNSMNKLPSVSQLINPQQRNALTPTTIPDGMGANIPMMGTHMPMAG 420
           SPSSYGNSSPPLNKMNSMNKLPSVSQLINPQQRNALTPTTIPDGMGANIPMMGTHMPMAG
Sbjct: 361 SPSSYGNSSPPLNKMNSMNKLPSVSQLINPQQRNALTPTTIPDGMGANIPMMGTHMPMAG 420

Query: 421 DMNGLSPTQALPPPLSMPSTSHCTPPPPYPTDCSIVRIWQV 461
           DMNGLSPTQALPPPLSMPSTSHCTPPPPYPTDCSIVRIWQV
Sbjct: 421 DMNGLSPTQALPPPLSMPSTSHCTPPPPYPTDCSIVRIWQV 461


>gi|169234661 tumor protein p63 isoform 4 [Homo sapiens]
          Length = 586

 Score =  937 bits (2421), Expect = 0.0
 Identities = 456/456 (100%), Positives = 456/456 (100%)

Query: 1   MLYLENNAQTQFSEPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSS 60
           MLYLENNAQTQFSEPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSS
Sbjct: 1   MLYLENNAQTQFSEPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSS 60

Query: 61  TFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIK 120
           TFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIK
Sbjct: 61  TFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIK 120

Query: 121 VMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQ 180
           VMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQ
Sbjct: 121 VMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQ 180

Query: 181 YVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQV 240
           YVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQV
Sbjct: 181 YVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQV 240

Query: 241 LGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRR 300
           LGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRR
Sbjct: 241 LGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRR 300

Query: 301 SPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSIQ 360
           SPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSIQ
Sbjct: 301 SPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSIQ 360

Query: 361 SPSSYGNSSPPLNKMNSMNKLPSVSQLINPQQRNALTPTTIPDGMGANIPMMGTHMPMAG 420
           SPSSYGNSSPPLNKMNSMNKLPSVSQLINPQQRNALTPTTIPDGMGANIPMMGTHMPMAG
Sbjct: 361 SPSSYGNSSPPLNKMNSMNKLPSVSQLINPQQRNALTPTTIPDGMGANIPMMGTHMPMAG 420

Query: 421 DMNGLSPTQALPPPLSMPSTSHCTPPPPYPTDCSIV 456
           DMNGLSPTQALPPPLSMPSTSHCTPPPPYPTDCSIV
Sbjct: 421 DMNGLSPTQALPPPLSMPSTSHCTPPPPYPTDCSIV 456


>gi|169234657 tumor protein p63 isoform 2 [Homo sapiens]
          Length = 555

 Score =  920 bits (2379), Expect = 0.0
 Identities = 447/447 (100%), Positives = 447/447 (100%)

Query: 15  PQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSN 74
           PQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSN
Sbjct: 109 PQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSN 168

Query: 75  TDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAM 134
           TDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAM
Sbjct: 169 TDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAM 228

Query: 135 PVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLV 194
           PVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLV
Sbjct: 229 PVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLV 288

Query: 195 PYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACP 254
           PYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACP
Sbjct: 289 PYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACP 348

Query: 255 GRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRRSPDDELLYLPVRGR 314
           GRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRRSPDDELLYLPVRGR
Sbjct: 349 GRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRRSPDDELLYLPVRGR 408

Query: 315 ETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSIQSPSSYGNSSPPLNK 374
           ETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSIQSPSSYGNSSPPLNK
Sbjct: 409 ETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSIQSPSSYGNSSPPLNK 468

Query: 375 MNSMNKLPSVSQLINPQQRNALTPTTIPDGMGANIPMMGTHMPMAGDMNGLSPTQALPPP 434
           MNSMNKLPSVSQLINPQQRNALTPTTIPDGMGANIPMMGTHMPMAGDMNGLSPTQALPPP
Sbjct: 469 MNSMNKLPSVSQLINPQQRNALTPTTIPDGMGANIPMMGTHMPMAGDMNGLSPTQALPPP 528

Query: 435 LSMPSTSHCTPPPPYPTDCSIVRIWQV 461
           LSMPSTSHCTPPPPYPTDCSIVRIWQV
Sbjct: 529 LSMPSTSHCTPPPPYPTDCSIVRIWQV 555


>gi|31543818 tumor protein p63 isoform 1 [Homo sapiens]
          Length = 680

 Score =  909 bits (2350), Expect = 0.0
 Identities = 442/442 (100%), Positives = 442/442 (100%)

Query: 15  PQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSN 74
           PQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSN
Sbjct: 109 PQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSN 168

Query: 75  TDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAM 134
           TDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAM
Sbjct: 169 TDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAM 228

Query: 135 PVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLV 194
           PVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLV
Sbjct: 229 PVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLV 288

Query: 195 PYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACP 254
           PYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACP
Sbjct: 289 PYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACP 348

Query: 255 GRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRRSPDDELLYLPVRGR 314
           GRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRRSPDDELLYLPVRGR
Sbjct: 349 GRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRRSPDDELLYLPVRGR 408

Query: 315 ETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSIQSPSSYGNSSPPLNK 374
           ETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSIQSPSSYGNSSPPLNK
Sbjct: 409 ETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSIQSPSSYGNSSPPLNK 468

Query: 375 MNSMNKLPSVSQLINPQQRNALTPTTIPDGMGANIPMMGTHMPMAGDMNGLSPTQALPPP 434
           MNSMNKLPSVSQLINPQQRNALTPTTIPDGMGANIPMMGTHMPMAGDMNGLSPTQALPPP
Sbjct: 469 MNSMNKLPSVSQLINPQQRNALTPTTIPDGMGANIPMMGTHMPMAGDMNGLSPTQALPPP 528

Query: 435 LSMPSTSHCTPPPPYPTDCSIV 456
           LSMPSTSHCTPPPPYPTDCSIV
Sbjct: 529 LSMPSTSHCTPPPPYPTDCSIV 550


>gi|169234665 tumor protein p63 isoform 6 [Homo sapiens]
          Length = 393

 Score =  726 bits (1875), Expect = 0.0
 Identities = 355/355 (100%), Positives = 355/355 (100%)

Query: 1   MLYLENNAQTQFSEPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSS 60
           MLYLENNAQTQFSEPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSS
Sbjct: 1   MLYLENNAQTQFSEPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSS 60

Query: 61  TFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIK 120
           TFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIK
Sbjct: 61  TFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIK 120

Query: 121 VMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQ 180
           VMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQ
Sbjct: 121 VMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQ 180

Query: 181 YVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQV 240
           YVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQV
Sbjct: 181 YVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQV 240

Query: 241 LGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRR 300
           LGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRR
Sbjct: 241 LGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRR 300

Query: 301 SPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQK 355
           SPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQK
Sbjct: 301 SPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQK 355


>gi|169234659 tumor protein p63 isoform 3 [Homo sapiens]
          Length = 487

 Score =  699 bits (1804), Expect = 0.0
 Identities = 341/341 (100%), Positives = 341/341 (100%)

Query: 15  PQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSN 74
           PQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSN
Sbjct: 109 PQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSN 168

Query: 75  TDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAM 134
           TDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAM
Sbjct: 169 TDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAM 228

Query: 135 PVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLV 194
           PVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLV
Sbjct: 229 PVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLV 288

Query: 195 PYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACP 254
           PYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACP
Sbjct: 289 PYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACP 348

Query: 255 GRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRRSPDDELLYLPVRGR 314
           GRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRRSPDDELLYLPVRGR
Sbjct: 349 GRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRRSPDDELLYLPVRGR 408

Query: 315 ETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQK 355
           ETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQK
Sbjct: 409 ETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQK 449


>gi|187829017 tumor protein p73 isoform c [Homo sapiens]
          Length = 450

 Score =  546 bits (1407), Expect = e-155
 Identities = 285/448 (63%), Positives = 335/448 (74%), Gaps = 27/448 (6%)

Query: 22  LLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSNTDYPGPH 81
           LL+S   Q+ + ++S SPY  +HA  SV   SPYAQPSSTFD +SP+P IPSNTDYPGPH
Sbjct: 18  LLSSTMDQMSSRAASASPYTPEHAA-SVPTHSPYAQPSSTFDTMSPAPVIPSNTDYPGPH 76

Query: 82  SFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAE 141
            F+V+FQQSSTAKSATWTYS  LKKLYCQIAKTCPIQIKV TPPP G  IRAMPVYKKAE
Sbjct: 77  HFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPPPPGTAIRAMPVYKKAE 136

Query: 142 HVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQV 201
           HVT+VVKRCPNHEL R+FNEGQ AP SHLIRVEGN+ +QYV+DP+TGRQSV+VPYEPPQV
Sbjct: 137 HVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQV 196

Query: 202 GTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACPGRDRKAD 261
           GTEFTT+LYNFMCNSSCVGGMNRRPILII+TLE RDGQVLGRR FE RICACPGRDRKAD
Sbjct: 197 GTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGRDRKAD 256

Query: 262 EDSIRKQQV--SDSTKNGDGTKRPFRQNTHGIQM--TSIKKRRSPDDELLYLPVRGRETY 317
           ED  R+QQ     S KNG  +KR F+Q+   +      +KKRR  D++  YL VRGRE +
Sbjct: 257 EDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRHGDEDTYYLQVRGRENF 316

Query: 318 EMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSIQSPSSYGNSSPPLNKMN- 376
           E+L+K+KESLELM+ +PQ  +++YRQQQQ     LLQ+ + +Q P SYG    P+NK++ 
Sbjct: 317 EILMKLKESLELMELVPQPLVDSYRQQQQ-----LLQRPSHLQ-PPSYGPVLSPMNKVHG 370

Query: 377 SMNKLPSVSQLIN--PQQRNALTPTTIPDGMGANIPMMGTH---MPMAGDMNGLSPTQAL 431
            MNKLPSV+QL+   P   +A TP   P G G    M+  H   +P  G+M+     Q  
Sbjct: 371 GMNKLPSVNQLVGQPPPHSSAATPNLGPVGPG----MLNNHGHAVPANGEMSSSHSAQ-- 424

Query: 432 PPPLSMPSTSHCTPPPPYPTDCSIVRIW 459
               SM S SHCTPPPPY  D S+VR W
Sbjct: 425 ----SMVSGSHCTPPPPYHADPSLVRTW 448


>gi|187828902 tumor protein p73 isoform b [Homo sapiens]
          Length = 587

 Score =  540 bits (1392), Expect = e-154
 Identities = 283/445 (63%), Positives = 333/445 (74%), Gaps = 27/445 (6%)

Query: 22  LLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSNTDYPGPH 81
           LL+S   Q+ + ++S SPY  +HA  SV   SPYAQPSSTFD +SP+P IPSNTDYPGPH
Sbjct: 18  LLSSTMDQMSSRAASASPYTPEHAA-SVPTHSPYAQPSSTFDTMSPAPVIPSNTDYPGPH 76

Query: 82  SFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAE 141
            F+V+FQQSSTAKSATWTYS  LKKLYCQIAKTCPIQIKV TPPP G  IRAMPVYKKAE
Sbjct: 77  HFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPPPPGTAIRAMPVYKKAE 136

Query: 142 HVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQV 201
           HVT+VVKRCPNHEL R+FNEGQ AP SHLIRVEGN+ +QYV+DP+TGRQSV+VPYEPPQV
Sbjct: 137 HVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQV 196

Query: 202 GTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACPGRDRKAD 261
           GTEFTT+LYNFMCNSSCVGGMNRRPILII+TLE RDGQVLGRR FE RICACPGRDRKAD
Sbjct: 197 GTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGRDRKAD 256

Query: 262 EDSIRKQQV--SDSTKNGDGTKRPFRQNTHGIQM--TSIKKRRSPDDELLYLPVRGRETY 317
           ED  R+QQ     S KNG  +KR F+Q+   +      +KKRR  D++  YL VRGRE +
Sbjct: 257 EDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRHGDEDTYYLQVRGRENF 316

Query: 318 EMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSIQSPSSYGNSSPPLNKMN- 376
           E+L+K+KESLELM+ +PQ  +++YRQQQQ     LLQ+ + +Q P SYG    P+NK++ 
Sbjct: 317 EILMKLKESLELMELVPQPLVDSYRQQQQ-----LLQRPSHLQ-PPSYGPVLSPMNKVHG 370

Query: 377 SMNKLPSVSQLIN--PQQRNALTPTTIPDGMGANIPMMGTH---MPMAGDMNGLSPTQAL 431
            MNKLPSV+QL+   P   +A TP   P G G    M+  H   +P  G+M+     Q  
Sbjct: 371 GMNKLPSVNQLVGQPPPHSSAATPNLGPVGPG----MLNNHGHAVPANGEMSSSHSAQ-- 424

Query: 432 PPPLSMPSTSHCTPPPPYPTDCSIV 456
               SM S SHCTPPPPY  D S+V
Sbjct: 425 ----SMVSGSHCTPPPPYHADPSLV 445


>gi|4885645 tumor protein p73 isoform a [Homo sapiens]
          Length = 636

 Score =  540 bits (1392), Expect = e-154
 Identities = 283/445 (63%), Positives = 333/445 (74%), Gaps = 27/445 (6%)

Query: 22  LLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSNTDYPGPH 81
           LL+S   Q+ + ++S SPY  +HA  SV   SPYAQPSSTFD +SP+P IPSNTDYPGPH
Sbjct: 67  LLSSTMDQMSSRAASASPYTPEHAA-SVPTHSPYAQPSSTFDTMSPAPVIPSNTDYPGPH 125

Query: 82  SFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAE 141
            F+V+FQQSSTAKSATWTYS  LKKLYCQIAKTCPIQIKV TPPP G  IRAMPVYKKAE
Sbjct: 126 HFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPPPPGTAIRAMPVYKKAE 185

Query: 142 HVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQV 201
           HVT+VVKRCPNHEL R+FNEGQ AP SHLIRVEGN+ +QYV+DP+TGRQSV+VPYEPPQV
Sbjct: 186 HVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQV 245

Query: 202 GTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACPGRDRKAD 261
           GTEFTT+LYNFMCNSSCVGGMNRRPILII+TLE RDGQVLGRR FE RICACPGRDRKAD
Sbjct: 246 GTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGRDRKAD 305

Query: 262 EDSIRKQQV--SDSTKNGDGTKRPFRQNTHGIQM--TSIKKRRSPDDELLYLPVRGRETY 317
           ED  R+QQ     S KNG  +KR F+Q+   +      +KKRR  D++  YL VRGRE +
Sbjct: 306 EDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRHGDEDTYYLQVRGRENF 365

Query: 318 EMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSIQSPSSYGNSSPPLNKMN- 376
           E+L+K+KESLELM+ +PQ  +++YRQQQQ     LLQ+ + +Q P SYG    P+NK++ 
Sbjct: 366 EILMKLKESLELMELVPQPLVDSYRQQQQ-----LLQRPSHLQ-PPSYGPVLSPMNKVHG 419

Query: 377 SMNKLPSVSQLIN--PQQRNALTPTTIPDGMGANIPMMGTH---MPMAGDMNGLSPTQAL 431
            MNKLPSV+QL+   P   +A TP   P G G    M+  H   +P  G+M+     Q  
Sbjct: 420 GMNKLPSVNQLVGQPPPHSSAATPNLGPVGPG----MLNNHGHAVPANGEMSSSHSAQ-- 473

Query: 432 PPPLSMPSTSHCTPPPPYPTDCSIV 456
               SM S SHCTPPPPY  D S+V
Sbjct: 474 ----SMVSGSHCTPPPPYHADPSLV 494


>gi|187829052 tumor protein p73 isoform d [Homo sapiens]
          Length = 426

 Score =  481 bits (1238), Expect = e-136
 Identities = 235/329 (71%), Positives = 271/329 (82%), Gaps = 5/329 (1%)

Query: 22  LLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSNTDYPGPH 81
           LL+S   Q+ + ++S SPY  +HA  SV   SPYAQPSSTFD +SP+P IPSNTDYPGPH
Sbjct: 18  LLSSTMDQMSSRAASASPYTPEHAA-SVPTHSPYAQPSSTFDTMSPAPVIPSNTDYPGPH 76

Query: 82  SFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAE 141
            F+V+FQQSSTAKSATWTYS  LKKLYCQIAKTCPIQIKV TPPP G  IRAMPVYKKAE
Sbjct: 77  HFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPPPPGTAIRAMPVYKKAE 136

Query: 142 HVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQV 201
           HVT+VVKRCPNHEL R+FNEGQ AP SHLIRVEGN+ +QYV+DP+TGRQSV+VPYEPPQV
Sbjct: 137 HVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQV 196

Query: 202 GTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACPGRDRKAD 261
           GTEFTT+LYNFMCNSSCVGGMNRRPILII+TLE RDGQVLGRR FE RICACPGRDRKAD
Sbjct: 197 GTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGRDRKAD 256

Query: 262 EDSIRKQQV--SDSTKNGDGTKRPFRQNTHGIQM--TSIKKRRSPDDELLYLPVRGRETY 317
           ED  R+QQ     S KNG  +KR F+Q+   +      +KKRR  D++  YL VRGRE +
Sbjct: 257 EDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRHGDEDTYYLQVRGRENF 316

Query: 318 EMLLKIKESLELMQYLPQHTIETYRQQQQ 346
           E+L+K+KESLELM+ +PQ  +++YRQQQQ
Sbjct: 317 EILMKLKESLELMELVPQPLVDSYRQQQQ 345


>gi|187830777 tumor protein p53 isoform a [Homo sapiens]
          Length = 393

 Score =  273 bits (697), Expect = 3e-73
 Identities = 138/283 (48%), Positives = 188/283 (66%), Gaps = 10/283 (3%)

Query: 51  APSPYAQPSSTFDALSPS----PAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKK 106
           AP+P A P+    A +PS     ++PS   Y G + F + F  S TAKS T TYS  L K
Sbjct: 74  APAP-AAPTPAAPAPAPSWPLSSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNK 132

Query: 107 LYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAP 166
           ++CQ+AKTCP+Q+ V + PP G  +RAM +YK+++H+TEVV+RCP+HE  R  +   +AP
Sbjct: 133 MFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHE--RCSDSDGLAP 190

Query: 167 PSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRP 226
           P HLIRVEGN   +Y++D  T R SV+VPYEPP+VG++ TT+ YN+MCNSSC+GGMNRRP
Sbjct: 191 PQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRP 250

Query: 227 ILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQ 286
           IL I+TLE   G +LGR  FE R+CACPGRDR+ +E+++RK+           TKR    
Sbjct: 251 ILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGEPHHELPPGSTKRALPN 310

Query: 287 NTHGIQMTSIKKRRSPDDELLYLPVRGRETYEMLLKIKESLEL 329
           NT     +   K++  D E   L +RGRE +EM  ++ E+LEL
Sbjct: 311 NT---SSSPQPKKKPLDGEYFTLQIRGRERFEMFRELNEALEL 350


>gi|120407068 tumor protein p53 isoform a [Homo sapiens]
          Length = 393

 Score =  273 bits (697), Expect = 3e-73
 Identities = 138/283 (48%), Positives = 188/283 (66%), Gaps = 10/283 (3%)

Query: 51  APSPYAQPSSTFDALSPS----PAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKK 106
           AP+P A P+    A +PS     ++PS   Y G + F + F  S TAKS T TYS  L K
Sbjct: 74  APAP-AAPTPAAPAPAPSWPLSSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNK 132

Query: 107 LYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAP 166
           ++CQ+AKTCP+Q+ V + PP G  +RAM +YK+++H+TEVV+RCP+HE  R  +   +AP
Sbjct: 133 MFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHE--RCSDSDGLAP 190

Query: 167 PSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRP 226
           P HLIRVEGN   +Y++D  T R SV+VPYEPP+VG++ TT+ YN+MCNSSC+GGMNRRP
Sbjct: 191 PQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRP 250

Query: 227 ILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQ 286
           IL I+TLE   G +LGR  FE R+CACPGRDR+ +E+++RK+           TKR    
Sbjct: 251 ILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGEPHHELPPGSTKRALPN 310

Query: 287 NTHGIQMTSIKKRRSPDDELLYLPVRGRETYEMLLKIKESLEL 329
           NT     +   K++  D E   L +RGRE +EM  ++ E+LEL
Sbjct: 311 NT---SSSPQPKKKPLDGEYFTLQIRGRERFEMFRELNEALEL 350


>gi|187830855 tumor protein p53 isoform b [Homo sapiens]
          Length = 341

 Score =  253 bits (645), Expect = 3e-67
 Identities = 124/242 (51%), Positives = 166/242 (68%), Gaps = 7/242 (2%)

Query: 51  APSPYAQPSSTFDALSPS----PAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKK 106
           AP+P A P+    A +PS     ++PS   Y G + F + F  S TAKS T TYS  L K
Sbjct: 74  APAP-AAPTPAAPAPAPSWPLSSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNK 132

Query: 107 LYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAP 166
           ++CQ+AKTCP+Q+ V + PP G  +RAM +YK+++H+TEVV+RCP+HE  R  +   +AP
Sbjct: 133 MFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHE--RCSDSDGLAP 190

Query: 167 PSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRP 226
           P HLIRVEGN   +Y++D  T R SV+VPYEPP+VG++ TT+ YN+MCNSSC+GGMNRRP
Sbjct: 191 PQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRP 250

Query: 227 ILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQ 286
           IL I+TLE   G +LGR  FE R+CACPGRDR+ +E+++RK+           TKR    
Sbjct: 251 ILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGEPHHELPPGSTKRALPN 310

Query: 287 NT 288
           NT
Sbjct: 311 NT 312


>gi|187830823 tumor protein p53 isoform c [Homo sapiens]
          Length = 346

 Score =  253 bits (645), Expect = 3e-67
 Identities = 124/242 (51%), Positives = 166/242 (68%), Gaps = 7/242 (2%)

Query: 51  APSPYAQPSSTFDALSPS----PAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKK 106
           AP+P A P+    A +PS     ++PS   Y G + F + F  S TAKS T TYS  L K
Sbjct: 74  APAP-AAPTPAAPAPAPSWPLSSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNK 132

Query: 107 LYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAP 166
           ++CQ+AKTCP+Q+ V + PP G  +RAM +YK+++H+TEVV+RCP+HE  R  +   +AP
Sbjct: 133 MFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHE--RCSDSDGLAP 190

Query: 167 PSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRP 226
           P HLIRVEGN   +Y++D  T R SV+VPYEPP+VG++ TT+ YN+MCNSSC+GGMNRRP
Sbjct: 191 PQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRP 250

Query: 227 ILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQ 286
           IL I+TLE   G +LGR  FE R+CACPGRDR+ +E+++RK+           TKR    
Sbjct: 251 ILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGEPHHELPPGSTKRALPN 310

Query: 287 NT 288
           NT
Sbjct: 311 NT 312


>gi|187830894 tumor protein p53 isoform d [Homo sapiens]
          Length = 261

 Score =  236 bits (603), Expect = 2e-62
 Identities = 113/223 (50%), Positives = 156/223 (69%), Gaps = 5/223 (2%)

Query: 107 LYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAP 166
           ++CQ+AKTCP+Q+ V + PP G  +RAM +YK+++H+TEVV+RCP+HE  R  +   +AP
Sbjct: 1   MFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHE--RCSDSDGLAP 58

Query: 167 PSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRP 226
           P HLIRVEGN   +Y++D  T R SV+VPYEPP+VG++ TT+ YN+MCNSSC+GGMNRRP
Sbjct: 59  PQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRP 118

Query: 227 ILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQ 286
           IL I+TLE   G +LGR  FE R+CACPGRDR+ +E+++RK+           TKR    
Sbjct: 119 ILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGEPHHELPPGSTKRALPN 178

Query: 287 NTHGIQMTSIKKRRSPDDELLYLPVRGRETYEMLLKIKESLEL 329
           NT     +   K++  D E   L +RGRE +EM  ++ E+LEL
Sbjct: 179 NT---SSSPQPKKKPLDGEYFTLQIRGRERFEMFRELNEALEL 218


>gi|187830909 tumor protein p53 isoform f [Homo sapiens]
          Length = 214

 Score =  216 bits (551), Expect = 3e-56
 Identities = 99/182 (54%), Positives = 134/182 (73%), Gaps = 2/182 (1%)

Query: 107 LYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAP 166
           ++CQ+AKTCP+Q+ V + PP G  +RAM +YK+++H+TEVV+RCP+HE  R  +   +AP
Sbjct: 1   MFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHE--RCSDSDGLAP 58

Query: 167 PSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRP 226
           P HLIRVEGN   +Y++D  T R SV+VPYEPP+VG++ TT+ YN+MCNSSC+GGMNRRP
Sbjct: 59  PQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRP 118

Query: 227 ILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQ 286
           IL I+TLE   G +LGR  FE R+CACPGRDR+ +E+++RK+           TKR    
Sbjct: 119 ILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGEPHHELPPGSTKRALPN 178

Query: 287 NT 288
           NT
Sbjct: 179 NT 180


>gi|187830901 tumor protein p53 isoform e [Homo sapiens]
          Length = 209

 Score =  216 bits (551), Expect = 3e-56
 Identities = 99/182 (54%), Positives = 134/182 (73%), Gaps = 2/182 (1%)

Query: 107 LYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAP 166
           ++CQ+AKTCP+Q+ V + PP G  +RAM +YK+++H+TEVV+RCP+HE  R  +   +AP
Sbjct: 1   MFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHE--RCSDSDGLAP 58

Query: 167 PSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRP 226
           P HLIRVEGN   +Y++D  T R SV+VPYEPP+VG++ TT+ YN+MCNSSC+GGMNRRP
Sbjct: 59  PQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRP 118

Query: 227 ILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQ 286
           IL I+TLE   G +LGR  FE R+CACPGRDR+ +E+++RK+           TKR    
Sbjct: 119 ILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGEPHHELPPGSTKRALPN 178

Query: 287 NT 288
           NT
Sbjct: 179 NT 180


>gi|7662302 TBK1 binding protein 1 [Homo sapiens]
          Length = 615

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 51/221 (23%), Positives = 84/221 (38%), Gaps = 21/221 (9%)

Query: 241 LGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRR 300
           L RR  E  + A  G  R A    +R++Q+    +   G  +   Q T    + S +  R
Sbjct: 224 LERRRLEEALEAAQGEARGAQ---LREEQLQAECERLQGELKQL-QETRAQDLASNQSER 279

Query: 301 SP------DDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQ 354
                    D+ + L +   E  E L +++E   L   + +  ++   +   Q+H  L Q
Sbjct: 280 DMAWVKRVGDDQVNLALAYTELTEELGRLRELSSLQGRILRTLLQEQARSGGQRHSPLSQ 339

Query: 355 KQT---SIQSPSSYGNSSPPLNKMNSM--NKLPSVSQLINPQQRNALTPTTIPDGMGANI 409
           + +      SPS    ++PP     S    +   V    +PQQR +    + P       
Sbjct: 340 RHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPS------ 393

Query: 410 PMMGTHMPMAGDMNGLSPTQALPPPLSMPSTSHCTPPPPYP 450
           P+     P+       SP +  P P S P+     PPPP P
Sbjct: 394 PVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPPP 434


>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
            sapiens]
          Length = 4911

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 47/175 (26%), Positives = 71/175 (40%), Gaps = 19/175 (10%)

Query: 292  QMTSIKKRRSPDDELLYLPVRGRET---------YEMLLKIKES--LELMQYLPQHTIET 340
            Q  SI      D EL   P++ RE+          +M  K K+   +E  Q L Q   E 
Sbjct: 1721 QQDSIDPSSRIDSELFKDPLKQRESEHEQEWKFRQQMRQKSKQQAKIEATQKLEQVKNEQ 1780

Query: 341  YRQQQQQQHQHLLQKQTSIQSPSSYGNSSPPLNKMNSMNKLPSVS---QLINPQQRNALT 397
             +QQQQQ     L  Q+   +PSS G  SP   +  + N  P+ S   +L   Q  +  T
Sbjct: 1781 QQQQQQQFGSQHLLVQSGSDTPSS-GIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPT 1839

Query: 398  PTTIPD----GMGANIPMMGTHMPMAGDMNGLSPTQALPPPLSMPSTSHCTPPPP 448
             T+  D          P   + +P+   ++    +Q   P +  P +S+  PP P
Sbjct: 1840 STSSDDVFVKPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSP 1894



 Score = 34.3 bits (77), Expect = 0.24
 Identities = 44/177 (24%), Positives = 63/177 (35%), Gaps = 20/177 (11%)

Query: 279  GTKRPFRQNTHGIQMTSIKKRRSPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTI 338
            G  R  ++     Q T+ K  R   +E         E   M+ K  E +   Q      I
Sbjct: 3203 GAHRKSKKALSAKQRTAKKAGREFPEEDAEQLKHVTEQQSMVQKQLEQIRKQQKEHAELI 3262

Query: 339  ETYRQQQQQQ---HQHLLQKQTSIQSPSSYGNSSPPLNKMNSMNKLPSVSQLINPQQRNA 395
            E YR +QQQQ       +      Q P   G + P +    S    P V Q +  QQ   
Sbjct: 3263 EDYRIKQQQQCAMAPPTMMPSVQPQPPLIPGATPPTM----SQPTFPMVPQQLQHQQHTT 3318

Query: 396  L-----TPTTIPDGMGANIPMMGTHMPMAGDMNGLSPTQALPPPLSMPSTSHCTPPP 447
            +     +P  +P   G        H+P       L+P +  PP   +P  + CTP P
Sbjct: 3319 VISGHTSPVRMPSLPGWQPNSAPAHLP-------LNPPRIQPPIAQLPIKT-CTPAP 3367


>gi|56549694 enabled homolog isoform a [Homo sapiens]
          Length = 591

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 34/131 (25%), Positives = 56/131 (42%), Gaps = 8/131 (6%)

Query: 324 KESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSIQSPSSYGNSSPPLNKM--NSMNKL 381
           ++  E ++ L +   E  RQ+Q ++ Q   +++  I S ++  +   PLN +  +S    
Sbjct: 229 RQERERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASE 288

Query: 382 PSVSQLINPQQRNALTPTTIPDGMGANIPMMGTHMPM--AGDMNGLSPTQALPPPLSMPS 439
           P +     P +    TP+     +G   P     +P   A     L P    PPP  +PS
Sbjct: 289 PGLQAASQPAE----TPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPS 344

Query: 440 TSHCTPPPPYP 450
           T    PPPP P
Sbjct: 345 TGPPPPPPPPP 355


>gi|39930375 enabled homolog isoform b [Homo sapiens]
          Length = 570

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 34/131 (25%), Positives = 56/131 (42%), Gaps = 8/131 (6%)

Query: 324 KESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSIQSPSSYGNSSPPLNKM--NSMNKL 381
           ++  E ++ L +   E  RQ+Q ++ Q   +++  I S ++  +   PLN +  +S    
Sbjct: 229 RQERERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASE 288

Query: 382 PSVSQLINPQQRNALTPTTIPDGMGANIPMMGTHMPM--AGDMNGLSPTQALPPPLSMPS 439
           P +     P +    TP+     +G   P     +P   A     L P    PPP  +PS
Sbjct: 289 PGLQAASQPAE----TPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPS 344

Query: 440 TSHCTPPPPYP 450
           T    PPPP P
Sbjct: 345 TGPPPPPPPPP 355


>gi|55953100 tubby like protein 4 isoform 1 [Homo sapiens]
          Length = 1543

 Score = 38.9 bits (89), Expect = 0.010
 Identities = 39/148 (26%), Positives = 64/148 (43%), Gaps = 23/148 (15%)

Query: 333  LPQHTIETYRQQQQQQHQHLLQKQTSIQSPSSYGNSSPPLNKMNSM----NKLPSVSQLI 388
            LP+  + T ++    Q   +L +   +    +   S P   K++S+     +   VS+L 
Sbjct: 1109 LPEAAV-TLKRPPPYQWDPMLGEDVWVPQERTAQTSGPNPLKLSSLMLSQGQHLDVSRLP 1167

Query: 389  NPQQRNALTPT-TIPDGMGANIPMMGTHM--PMAGDMNGLSPTQALPP------------ 433
                ++  +PT T   G G  +P  G++   P+ G     SP  AL P            
Sbjct: 1168 FISPKSPASPTATFQTGYGMGVPYPGSYNNPPLPGVQAPCSPKDALSPTQFAQQEPAVVL 1227

Query: 434  -PLSMPSTSHCTPPPPYP--TDCSIVRI 458
             PL  PS S+CT PP YP  + CS +++
Sbjct: 1228 QPLYPPSLSYCTLPPMYPGSSTCSSLQL 1255


>gi|157168329 formin 1 [Homo sapiens]
          Length = 1196

 Score = 38.1 bits (87), Expect = 0.017
 Identities = 28/112 (25%), Positives = 45/112 (40%), Gaps = 4/112 (3%)

Query: 339 ETYRQQQQQQHQHLLQKQTSIQSPSSYGNSSPPLNKMNSMNKLPSVSQLINPQQRNALTP 398
           +T R  Q    +  +   + +  P+ + +    L  M  M    +  + + P   +   P
Sbjct: 598 KTTRSNQLVPKKLNISSLSQLSPPNDHKDIHAALQPMEGMAS--NQQKALPPPPASIPPP 655

Query: 399 TTIPDGMGANIPMMGTHMPMAGDMNGLSPTQALPPPLSMPSTSHCTPPPPYP 450
             +P G+G+  P     MP       L P    PPPL  PS++   PPPP P
Sbjct: 656 PPLPSGLGSLSP--APPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPP 705


>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
          Length = 2063

 Score = 38.1 bits (87), Expect = 0.017
 Identities = 34/119 (28%), Positives = 48/119 (40%), Gaps = 8/119 (6%)

Query: 335 QHTIETYRQQQQQQHQHLLQKQTSIQSPSSYGNSSPP--LNKMNSMNKLPSVSQLINPQQ 392
           Q   +  +QQQQQQ Q   Q+Q   + P  +    P     +  +  ++P V    N   
Sbjct: 264 QQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVP-VPPGWNQLP 322

Query: 393 RNALTPTTIPDGMGANIPMMG-THMPMAGDMNGLSPTQALPPPLSMPSTSHCTPPPPYP 450
             AL P      +G      G    P+ G M      QA P   ++ + SH  PPPPYP
Sbjct: 323 SGALQPPPAQGSLGTMTANQGWKKAPLPGPMQ--QQLQARPSLATVQTPSH--PPPPYP 377


>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
          Length = 788

 Score = 37.4 bits (85), Expect = 0.029
 Identities = 42/201 (20%), Positives = 75/201 (37%), Gaps = 22/201 (10%)

Query: 258 RKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGI--QMTSIKKRRSPDDELLYLPVRGRE 315
           ++  + ++++QQ     +     +   +Q    +  Q   +++++     L+ L     +
Sbjct: 170 QQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLH---HQ 226

Query: 316 TYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSIQSPSSYGNSSPPLNKM 375
             + + + ++ L+ +  L     +  +QQQQQQ Q  LQ Q  IQ P       PP    
Sbjct: 227 NQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPP---- 282

Query: 376 NSMNKLPSVSQLINPQQRNALTPTTIPDGMGANIPMMGTHMPMAGDMNGL-SPTQALP-- 432
                LP   Q ++  Q +   P      +  N P   + +P       L S  QALP  
Sbjct: 283 --SQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQP---SQLPPQSQTQPLVSQAQALPGQ 337

Query: 433 -----PPLSMPSTSHCTPPPP 448
                PPL           PP
Sbjct: 338 MLYTQPPLKFVRAPMVVQQPP 358


>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
          Length = 748

 Score = 37.4 bits (85), Expect = 0.029
 Identities = 42/201 (20%), Positives = 75/201 (37%), Gaps = 22/201 (10%)

Query: 258 RKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGI--QMTSIKKRRSPDDELLYLPVRGRE 315
           ++  + ++++QQ     +     +   +Q    +  Q   +++++     L+ L     +
Sbjct: 170 QQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLH---HQ 226

Query: 316 TYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSIQSPSSYGNSSPPLNKM 375
             + + + ++ L+ +  L     +  +QQQQQQ Q  LQ Q  IQ P       PP    
Sbjct: 227 NQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPP---- 282

Query: 376 NSMNKLPSVSQLINPQQRNALTPTTIPDGMGANIPMMGTHMPMAGDMNGL-SPTQALP-- 432
                LP   Q ++  Q +   P      +  N P   + +P       L S  QALP  
Sbjct: 283 --SQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQP---SQLPPQSQTQPLVSQAQALPGQ 337

Query: 433 -----PPLSMPSTSHCTPPPP 448
                PPL           PP
Sbjct: 338 MLYTQPPLKFVRAPMVVQQPP 358


>gi|48255900 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a2 isoform a [Homo sapiens]
          Length = 1590

 Score = 37.0 bits (84), Expect = 0.038
 Identities = 41/153 (26%), Positives = 55/153 (35%), Gaps = 30/153 (19%)

Query: 299 RRSPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTS 358
           R  P  E L L V+G+ T   L + ++  +  Q           QQQQQQ Q   Q Q  
Sbjct: 194 RGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQ-----------QQQQQQQQQQQQPQQQ 242

Query: 359 IQSPSSYGNSSPPLNKMNSMNKLPSVSQLINPQQRNALTPTTIPDGMGANIPMMGTHMPM 418
              P +     P L   N     PS      P+     TP  +P      +P  G     
Sbjct: 243 PPQPQTQQQQQPALVNYNR----PSGP---GPELSGPSTPQKLP------VPAPG----- 284

Query: 419 AGDMNGLSPTQALPPPLSMPSTSHCTPPPPYPT 451
            G  +   P  A PP  ++P  S   P P  P+
Sbjct: 285 -GRPSPAPPAAAQPPAAAVPGPSVPQPAPGQPS 316


>gi|48255898 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a2 isoform b [Homo sapiens]
          Length = 1572

 Score = 37.0 bits (84), Expect = 0.038
 Identities = 41/153 (26%), Positives = 55/153 (35%), Gaps = 30/153 (19%)

Query: 299 RRSPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTS 358
           R  P  E L L V+G+ T   L + ++  +  Q           QQQQQQ Q   Q Q  
Sbjct: 194 RGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQ-----------QQQQQQQQQQQQPQQQ 242

Query: 359 IQSPSSYGNSSPPLNKMNSMNKLPSVSQLINPQQRNALTPTTIPDGMGANIPMMGTHMPM 418
              P +     P L   N     PS      P+     TP  +P      +P  G     
Sbjct: 243 PPQPQTQQQQQPALVNYNR----PSGP---GPELSGPSTPQKLP------VPAPG----- 284

Query: 419 AGDMNGLSPTQALPPPLSMPSTSHCTPPPPYPT 451
            G  +   P  A PP  ++P  S   P P  P+
Sbjct: 285 -GRPSPAPPAAAQPPAAAVPGPSVPQPAPGQPS 316


>gi|32307124 nuclear receptor coactivator 3 isoform b [Homo sapiens]
          Length = 1420

 Score = 35.8 bits (81), Expect = 0.084
 Identities = 33/126 (26%), Positives = 51/126 (40%), Gaps = 9/126 (7%)

Query: 269  QVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRRSPDDELLYLPVRGRETYEMLLKIKESLE 328
            ++ + T  G    RP  Q   G     +  +RS   ELL    R +    M+ + ++  +
Sbjct: 1194 KMENPTAGGAAVMRPMMQPQQGFLNAQMVAQRSR--ELLSHHFRQQRVAMMMQQQQQQQQ 1251

Query: 329  LMQYLPQHTIETYRQQQQQQHQHLLQKQTSIQSPSSYGNSSPPLNKMNSMNKLPSVSQLI 388
              Q   Q       QQQQQQ Q   Q+QT   SP     +SP ++ + +   +P      
Sbjct: 1252 QQQQQQQ-------QQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQ 1304

Query: 389  NPQQRN 394
             P Q N
Sbjct: 1305 FPYQPN 1310



 Score = 30.4 bits (67), Expect = 3.5
 Identities = 31/106 (29%), Positives = 43/106 (40%), Gaps = 23/106 (21%)

Query: 359 IQSPSSYGNSSPPLNKMNSMNKLPSVSQLINPQQRNALTPTTIPDGMGAN-------IPM 411
           +QSPSSY N++  LN    M+  P  S  + P Q+N +     P   G+         P+
Sbjct: 448 MQSPSSYQNNNYGLN----MSSPPHGSPGLAPNQQNIMIS---PRNRGSPKIASHQFSPV 500

Query: 412 MGTHMPMAGDMN---------GLSPTQALPPPLSMPSTSHCTPPPP 448
            G H PMA   N          LS  QA+   +     S  + P P
Sbjct: 501 AGVHSPMASSGNTGNHSFSSSSLSALQAISEGVGTSLLSTLSSPGP 546


>gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo sapiens]
          Length = 1085

 Score = 35.4 bits (80), Expect = 0.11
 Identities = 50/208 (24%), Positives = 75/208 (36%), Gaps = 39/208 (18%)

Query: 254  PGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRRSPDDELLYLPVRG 313
            P R R+    S+      DS K  D    P R++T   Q T     +  D E +   +  
Sbjct: 907  PERRRRPGHGSLTNISRHDSLKKIDSP--PIRRSTSSGQYTGFNDHKPLDPETIAQDIE- 963

Query: 314  RETYEMLLKIKESLELM---QYLPQHTIETYRQQQQQQHQHLLQKQTSIQSPSSYGNSSP 370
             ET    L     LE     ++ P   ++T  Q +                     NS  
Sbjct: 964  -ETMNTALNELRELERQSTAKHAPDVVLDTLEQVK---------------------NSPT 1001

Query: 371  PLNKMNSMNKLPSVS-QLINPQQRNALTPTTIPDGMGANIPMMGTHMPMAGDMNGLSPTQ 429
            P     S++ L +V+ +   PQ R + + ++  D M    PM+   M +      L P  
Sbjct: 1002 PATSTESLSPLHNVALRSSEPQIRRSTSSSS--DTMSTFKPMVAPRMGVQ-----LKPPA 1054

Query: 430  ALPPPLSMPSTSHC---TPPPPYPTDCS 454
              P P  +P T+      PPP  PTD S
Sbjct: 1055 LRPKPAVLPKTNPTIGPAPPPQGPTDKS 1082


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.129    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,943,104
Number of Sequences: 37866
Number of extensions: 1082912
Number of successful extensions: 6637
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 166
Number of HSP's that attempted gapping in prelim test: 5467
Number of HSP's gapped (non-prelim): 983
length of query: 461
length of database: 18,247,518
effective HSP length: 106
effective length of query: 355
effective length of database: 14,233,722
effective search space: 5052971310
effective search space used: 5052971310
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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