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Search of human proteins with 112382220
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|112382220 chloride channel Ka isoform 1 [Homo sapiens]
(687 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|112382220 chloride channel Ka isoform 1 [Homo sapiens] 1376 0.0
gi|112382222 chloride channel Ka isoform 2 [Homo sapiens] 1370 0.0
gi|155969705 chloride channel Kb [Homo sapiens] 1266 0.0
gi|156104869 chloride channel 2 [Homo sapiens] 543 e-154
gi|119433677 chloride channel 1, skeletal muscle [Homo sapiens] 490 e-138
gi|153252026 chloride channel 4 [Homo sapiens] 193 4e-49
gi|189217923 chloride channel 5 isoform a [Homo sapiens] 187 3e-47
gi|189217921 chloride channel 5 isoform a [Homo sapiens] 187 3e-47
gi|4557473 chloride channel 5 isoform b [Homo sapiens] 187 3e-47
gi|55770838 chloride channel 3 isoform b [Homo sapiens] 178 1e-44
gi|55770840 chloride channel 3 isoform e [Homo sapiens] 174 2e-43
gi|167466160 chloride channel 7 isoform b [Homo sapiens] 147 3e-35
gi|14149607 chloride channel 7 isoform a [Homo sapiens] 147 3e-35
gi|4502873 chloride channel 6 isoform ClC-6a [Homo sapiens] 119 7e-27
gi|12025671 chloride channel 6 isoform ClC-6c [Homo sapiens] 73 1e-12
gi|12025673 chloride channel 6 isoform ClC-6d [Homo sapiens] 48 3e-05
gi|12025668 chloride channel 6 isoform ClC-6b [Homo sapiens] 48 3e-05
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] 31 3.3
gi|126352608 elastin isoform e precursor [Homo sapiens] 31 4.4
gi|126352446 elastin isoform d precursor [Homo sapiens] 31 4.4
gi|126352322 elastin isoform c precursor [Homo sapiens] 31 4.4
gi|126352700 elastin isoform b precursor [Homo sapiens] 31 4.4
gi|126352440 elastin isoform a precursor [Homo sapiens] 31 4.4
gi|156938237 ADP-ribosylation factor-like 17 isoform a [Homo sap... 31 4.4
gi|166063999 hypothetical protein LOC51326 isoform a [Homo sapiens] 31 4.4
gi|83035129 coiled-coil domain containing 108 isoform 1 [Homo sa... 30 5.7
gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sa... 30 9.7
gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo sa... 30 9.7
gi|84508631 phosphatidylglycerophosphate synthase 1 [Homo sapiens] 30 9.7
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr... 30 9.7
>gi|112382220 chloride channel Ka isoform 1 [Homo sapiens]
Length = 687
Score = 1376 bits (3562), Expect = 0.0
Identities = 687/687 (100%), Positives = 687/687 (100%)
Query: 1 MEELVGLREGFSGDPVTLQELWGPCPHIRRAIQGGLEWLKQKVFRLGEDWYFLMTLGVLM 60
MEELVGLREGFSGDPVTLQELWGPCPHIRRAIQGGLEWLKQKVFRLGEDWYFLMTLGVLM
Sbjct: 1 MEELVGLREGFSGDPVTLQELWGPCPHIRRAIQGGLEWLKQKVFRLGEDWYFLMTLGVLM 60
Query: 61 ALVSYAMNFAIGCVVRAHQWLYREIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGG 120
ALVSYAMNFAIGCVVRAHQWLYREIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGG
Sbjct: 61 ALVSYAMNFAIGCVVRAHQWLYREIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGG 120
Query: 121 SGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLFLGKVGPFVHLSVMIAAYL 180
SGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLFLGKVGPFVHLSVMIAAYL
Sbjct: 121 SGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLFLGKVGPFVHLSVMIAAYL 180
Query: 181 GRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGF 240
GRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGF
Sbjct: 181 GRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGF 240
Query: 241 FAATCGAFIFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGICGVLSCAYL 300
FAATCGAFIFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGICGVLSCAYL
Sbjct: 241 FAATCGAFIFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGICGVLSCAYL 300
Query: 301 FCQRTFLSFIKTNRYSSKLLATSKPVYSALATLLLASITYPPGVGHFLASRLSMKQHLDS 360
FCQRTFLSFIKTNRYSSKLLATSKPVYSALATLLLASITYPPGVGHFLASRLSMKQHLDS
Sbjct: 301 FCQRTFLSFIKTNRYSSKLLATSKPVYSALATLLLASITYPPGVGHFLASRLSMKQHLDS 360
Query: 361 LFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIP 420
LFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIP
Sbjct: 361 LFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIP 420
Query: 421 MPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIMPGGYALAGAAAFSGAVTH 480
MPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIMPGGYALAGAAAFSGAVTH
Sbjct: 421 MPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIMPGGYALAGAAAFSGAVTH 480
Query: 481 TISTALLAFELTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTIIVKKLPYLPRILGRNI 540
TISTALLAFELTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTIIVKKLPYLPRILGRNI
Sbjct: 481 TISTALLAFELTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTIIVKKLPYLPRILGRNI 540
Query: 541 GSHHVRVEHFMNHSITTLAKDTPLEEVVKVVTSTDVTEYPLVESTESQILVGIVQRAQLV 600
GSHHVRVEHFMNHSITTLAKDTPLEEVVKVVTSTDVTEYPLVESTESQILVGIVQRAQLV
Sbjct: 541 GSHHVRVEHFMNHSITTLAKDTPLEEVVKVVTSTDVTEYPLVESTESQILVGIVQRAQLV 600
Query: 601 QALQAEPPSRAPGHQQCLQDILARGCPTEPVTLTLFSETTLHQAQNLFKLLNLQSLFVTS 660
QALQAEPPSRAPGHQQCLQDILARGCPTEPVTLTLFSETTLHQAQNLFKLLNLQSLFVTS
Sbjct: 601 QALQAEPPSRAPGHQQCLQDILARGCPTEPVTLTLFSETTLHQAQNLFKLLNLQSLFVTS 660
Query: 661 RGRAVGCVSWVEMKKAISNLTNPPAPK 687
RGRAVGCVSWVEMKKAISNLTNPPAPK
Sbjct: 661 RGRAVGCVSWVEMKKAISNLTNPPAPK 687
>gi|112382222 chloride channel Ka isoform 2 [Homo sapiens]
Length = 686
Score = 1370 bits (3545), Expect = 0.0
Identities = 686/687 (99%), Positives = 686/687 (99%), Gaps = 1/687 (0%)
Query: 1 MEELVGLREGFSGDPVTLQELWGPCPHIRRAIQGGLEWLKQKVFRLGEDWYFLMTLGVLM 60
MEELVGLREGFSGDPVTLQELWGPCPHIRRAIQGGLEWLKQKVFRLGEDWYFLMTLGVLM
Sbjct: 1 MEELVGLREGFSGDPVTLQELWGPCPHIRRAIQGGLEWLKQKVFRLGEDWYFLMTLGVLM 60
Query: 61 ALVSYAMNFAIGCVVRAHQWLYREIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGG 120
ALVSYAMNFAIGCVVRAHQWLYREIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGG
Sbjct: 61 ALVSYAMNFAIGCVVRAHQWLYREIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGG 120
Query: 121 SGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLFLGKVGPFVHLSVMIAAYL 180
SGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLFLGKVGPFVHLSVMIAAYL
Sbjct: 121 SGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLFLGKVGPFVHLSVMIAAYL 180
Query: 181 GRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGF 240
GRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGF
Sbjct: 181 GRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGF 240
Query: 241 FAATCGAFIFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGICGVLSCAYL 300
FAATCGAFIFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGICGVLSCAYL
Sbjct: 241 FAATCGAFIFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGICGVLSCAYL 300
Query: 301 FCQRTFLSFIKTNRYSSKLLATSKPVYSALATLLLASITYPPGVGHFLASRLSMKQHLDS 360
FCQRTFLSFIKTNRYSSKLLATSKPVYSALATLLLASITYPPGVGHFLASRLSMKQHLDS
Sbjct: 301 FCQRTFLSFIKTNRYSSKLLATSKPVYSALATLLLASITYPPGVGHFLASRLSMKQHLDS 360
Query: 361 LFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIP 420
LFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIP
Sbjct: 361 LFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIP 420
Query: 421 MPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIMPGGYALAGAAAFSGAVTH 480
MPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIMPGGYALAGAAAFSGAVTH
Sbjct: 421 MPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIMPGGYALAGAAAFSGAVTH 480
Query: 481 TISTALLAFELTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTIIVKKLPYLPRILGRNI 540
TISTALLAFELTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTIIVKKLPYLPRILGRNI
Sbjct: 481 TISTALLAFELTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTIIVKKLPYLPRILGRNI 540
Query: 541 GSHHVRVEHFMNHSITTLAKDTPLEEVVKVVTSTDVTEYPLVESTESQILVGIVQRAQLV 600
GSHHVRVEHFMNHSITTLAKDTPLEEVVKVVTSTDVTEYPLVESTESQILVGIVQRAQLV
Sbjct: 541 GSHHVRVEHFMNHSITTLAKDTPLEEVVKVVTSTDVTEYPLVESTESQILVGIVQRAQLV 600
Query: 601 QALQAEPPSRAPGHQQCLQDILARGCPTEPVTLTLFSETTLHQAQNLFKLLNLQSLFVTS 660
QALQAEPPSRAPGH QCLQDILARGCPTEPVTLTLFSETTLHQAQNLFKLLNLQSLFVTS
Sbjct: 601 QALQAEPPSRAPGH-QCLQDILARGCPTEPVTLTLFSETTLHQAQNLFKLLNLQSLFVTS 659
Query: 661 RGRAVGCVSWVEMKKAISNLTNPPAPK 687
RGRAVGCVSWVEMKKAISNLTNPPAPK
Sbjct: 660 RGRAVGCVSWVEMKKAISNLTNPPAPK 686
>gi|155969705 chloride channel Kb [Homo sapiens]
Length = 687
Score = 1266 bits (3277), Expect = 0.0
Identities = 627/687 (91%), Positives = 652/687 (94%)
Query: 1 MEELVGLREGFSGDPVTLQELWGPCPHIRRAIQGGLEWLKQKVFRLGEDWYFLMTLGVLM 60
MEE VGLREG SG+PVTLQELWGPCP IRR I+GGLEWLKQK+FRLGEDWYFLMTLGVLM
Sbjct: 1 MEEFVGLREGSSGNPVTLQELWGPCPRIRRGIRGGLEWLKQKLFRLGEDWYFLMTLGVLM 60
Query: 61 ALVSYAMNFAIGCVVRAHQWLYREIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGG 120
ALVS AM+ A+ VVRAHQWLYREIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGG
Sbjct: 61 ALVSCAMDLAVESVVRAHQWLYREIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGG 120
Query: 121 SGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLFLGKVGPFVHLSVMIAAYL 180
SGIPE+KTMLAGV+LEDYLDIKNFGAKVVGLSCTLA GSTLFLGKVGPFVHLSVM+AAYL
Sbjct: 121 SGIPEVKTMLAGVVLEDYLDIKNFGAKVVGLSCTLACGSTLFLGKVGPFVHLSVMMAAYL 180
Query: 181 GRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGF 240
GRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSV DYWRGF
Sbjct: 181 GRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVWDYWRGF 240
Query: 241 FAATCGAFIFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGICGVLSCAYL 300
FAATCGAF+FRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGG+CG+L AYL
Sbjct: 241 FAATCGAFMFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGLCGILGSAYL 300
Query: 301 FCQRTFLSFIKTNRYSSKLLATSKPVYSALATLLLASITYPPGVGHFLASRLSMKQHLDS 360
FCQR F FI+ NR+SSKLLATSKPVYSALATL+LASITYPP G FLASRLSMKQHLDS
Sbjct: 301 FCQRIFFGFIRNNRFSSKLLATSKPVYSALATLVLASITYPPSAGRFLASRLSMKQHLDS 360
Query: 361 LFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIP 420
LFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIP
Sbjct: 361 LFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIP 420
Query: 421 MPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIMPGGYALAGAAAFSGAVTH 480
MPAGYFMPIF+ GAAIGRL GE L+ FPEGIV GG+TNPIMPGGYALAGAAAFSGAVTH
Sbjct: 421 MPAGYFMPIFVYGAAIGRLFGETLSFIFPEGIVAGGITNPIMPGGYALAGAAAFSGAVTH 480
Query: 481 TISTALLAFELTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTIIVKKLPYLPRILGRNI 540
TISTALLAFE+TGQIVHALPVLMAVLAANAIAQSCQPSFYDGT+IVKKLPYLPRILGRNI
Sbjct: 481 TISTALLAFEVTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTVIVKKLPYLPRILGRNI 540
Query: 541 GSHHVRVEHFMNHSITTLAKDTPLEEVVKVVTSTDVTEYPLVESTESQILVGIVQRAQLV 600
GSH VRVEHFMNHSITTLAKD PLEEVVKVVTSTDV +YPLVESTESQILVGIV+RAQLV
Sbjct: 541 GSHRVRVEHFMNHSITTLAKDMPLEEVVKVVTSTDVAKYPLVESTESQILVGIVRRAQLV 600
Query: 601 QALQAEPPSRAPGHQQCLQDILARGCPTEPVTLTLFSETTLHQAQNLFKLLNLQSLFVTS 660
QAL+AEPPS APGHQQCLQDILA GCPTEPVTL L ET+LH+A NLF+LLNL SLFVTS
Sbjct: 601 QALKAEPPSWAPGHQQCLQDILAAGCPTEPVTLKLSPETSLHEAHNLFELLNLHSLFVTS 660
Query: 661 RGRAVGCVSWVEMKKAISNLTNPPAPK 687
RGRAVGCVSWVEMKKAISNLTNPPAPK
Sbjct: 661 RGRAVGCVSWVEMKKAISNLTNPPAPK 687
>gi|156104869 chloride channel 2 [Homo sapiens]
Length = 898
Score = 543 bits (1400), Expect = e-154
Identities = 283/575 (49%), Positives = 387/575 (67%), Gaps = 9/575 (1%)
Query: 43 VFRLGEDWYFLMTLGVLMALVSYAMNFAIGCVVRAHQWLYREIGDSHLLRYLSWTVYPVA 102
V R+GEDW FL+ LG+LMALVS+ M++AI ++A QW+ R + S LL+YL+W YPV
Sbjct: 84 VSRVGEDWIFLVLLGLLMALVSWVMDYAIAACLQAQQWMSRGLNTSILLQYLAWVTYPVV 143
Query: 103 LVSFSSGFSQSITPSSGGSGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLF 162
L++FS+GF+Q + P + GSGIPE+KT+L GV+L++YL +K F AKV+GL+C L GS +
Sbjct: 144 LITFSAGFTQILAPQAVGSGIPEMKTILRGVVLKEYLTLKTFIAKVIGLTCAL--GSGMP 201
Query: 163 LGKVGPFVHLSVMIAAYLGRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLF 222
LGK GPFVH++ M AA L + + G EN+S+ EML AA AVGV FAAP GVLF
Sbjct: 202 LGKEGPFVHIASMCAALLSKFLSLFGGIYENESRNTEMLAAACAVGVGCCFAAPIGGVLF 261
Query: 223 SIEVMSSHFSVRDYWRGFFAATCGAFIFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEI 282
SIEV S+ F+VR+YWRGFFAAT AFIFR+LAV+N ++ETIT+L+KT FR+D PFDL E+
Sbjct: 262 SIEVTSTFFAVRNYWRGFFAATFSAFIFRVLAVWNRDEETITALFKTRFRLDFPFDLQEL 321
Query: 283 FFFVALGGICGVLSCAYLFCQRTFLSFIKTNRYSSKLLATSKPVYSALATLLLASITYPP 342
F +G G +++ R + ++ + ++ L + ++ AL TLL++++T+PP
Sbjct: 322 PAFAVIGIASGFGGALFVYLNRKIVQVMRKQKTINRFLMRKRLLFPALVTLLISTLTFPP 381
Query: 343 GVGHFLASRLSMKQHLDSLFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTL 402
G G F+A +LS K+ L +LFDN +W EEL+P W PR +F TL
Sbjct: 382 GFGQFMAGQLSQKETLVTLFDNRTWVRQGL------VEELEPPSTSQAWNPPRANVFLTL 435
Query: 403 AFFLVMKFWMLILATTIPMPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIM 462
F++MKFWM LATTIP+P G FMP+F++GAA GRL+GE++A FP+GI T T I+
Sbjct: 436 VIFILMKFWMSALATTIPVPCGAFMPVFVIGAAFGRLVGESMAAWFPDGIHTDSSTYRIV 495
Query: 463 PGGYALAGAAAFSGAVTHTISTALLAFELTGQIVHALPVLMAVLAANAIAQSCQPSFYDG 522
PGGYA+ GAAA +GAVTHT+STA++ FELTGQI H LPV++AV+ ANA+AQS QPS YD
Sbjct: 496 PGGYAVVGAAALAGAVTHTVSTAVIVFELTGQIAHILPVMIAVILANAVAQSLQPSLYDS 555
Query: 523 TIIVKKLPYLPRILGRNIGSHHVRVEHFMNHSITTLAKDTPLEEVVKVVTSTDVTEYPLV 582
I +KKLPYLP + + VRVE M + +A ++ + T LV
Sbjct: 556 IIRIKKLPYLPELGWGRHQQYRVRVEDIMVRDVPHVALSCTFRDLRLALHRTKGRMLALV 615
Query: 583 ESTESQILVGIVQRAQLVQALQAE-PPSRAPGHQQ 616
ES ES IL+G ++R+Q+V L A+ P+R H Q
Sbjct: 616 ESPESMILLGSIERSQVVALLGAQLSPARRRQHMQ 650
Score = 45.8 bits (107), Expect = 1e-04
Identities = 22/63 (34%), Positives = 34/63 (53%)
Query: 615 QQCLQDILARGCPTEPVTLTLFSETTLHQAQNLFKLLNLQSLFVTSRGRAVGCVSWVEMK 674
QQ + + C +P L T+LH+ +F LL + +VTS GR +G V+ E++
Sbjct: 777 QQLDEPVNFSDCKIDPAPFQLVERTSLHKTHTIFSLLGVDHAYVTSIGRLIGIVTLKELR 836
Query: 675 KAI 677
KAI
Sbjct: 837 KAI 839
>gi|119433677 chloride channel 1, skeletal muscle [Homo sapiens]
Length = 988
Score = 490 bits (1262), Expect = e-138
Identities = 249/560 (44%), Positives = 370/560 (66%), Gaps = 10/560 (1%)
Query: 45 RLGEDWYFLMTLGVLMALVSYAMNFAIGCVVRAHQWLYREIGDSHLLRYLSWTVYPVALV 104
+LGEDW FL+ LG+LMALVS++M++ ++A++W Y ++ S L++L W +P+ L+
Sbjct: 113 KLGEDWIFLVLLGLLMALVSWSMDYVSAKSLQAYKWSYAQMQPSLPLQFLVWVTFPLVLI 172
Query: 105 SFSSGFSQSITPSSGGSGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLFLG 164
FS+ F I+P + GSGIPE+KT+L GV+L++YL +K F AKVV L+ L GS + +G
Sbjct: 173 LFSALFCHLISPQAVGSGIPEMKTILRGVVLKEYLTMKAFVAKVVALTAGL--GSGIPVG 230
Query: 165 KVGPFVHLSVMIAAYLGRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSI 224
K GPFVH++ + AA L + + G E +++L AVGV F P GVLFSI
Sbjct: 231 KEGPFVHIASICAAVLSKFMSVFCGVYEQPYYYSDILTVGCAVGVGCCFGTPLGGVLFSI 290
Query: 225 EVMSSHFSVRDYWRGFFAATCGAFIFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFF 284
EV S++F+VR+YWRGFFAAT AF+FR+LAV+N + TIT+L++T+FR+D PFDL E+
Sbjct: 291 EVTSTYFAVRNYWRGFFAATFSAFVFRVLAVWNKDAVTITALFRTNFRMDFPFDLKELPA 350
Query: 285 FVALGGICGVLSCAYLFCQRTFLSFIKTNRYSSKLLATSKPVYSALATLLLASITYPPGV 344
F A+G CG+L +++ R + ++ ++ S+ LA + +Y + T ++AS T+PPG+
Sbjct: 351 FAAIGICCGLLGAVFVYLHRQVMLGVRKHKALSQFLAKHRLLYPGIVTFVIASFTFPPGM 410
Query: 345 GHFLASRLSMKQHLDSLFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAF 404
G F+A L ++ + +LFDN++W + PE L +W HPR + +
Sbjct: 411 GQFMAGELMPREAISTLFDNNTWVKHAGD-----PESLGQSAVW---IHPRVNVVIIIFL 462
Query: 405 FLVMKFWMLILATTIPMPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIMPG 464
F VMKFWM I+ATT+P+P G FMP+F+LGAA GRL+GE +A+ FP+GI+ + I+PG
Sbjct: 463 FFVMKFWMSIVATTMPIPCGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDDIIYKILPG 522
Query: 465 GYALAGAAAFSGAVTHTISTALLAFELTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTI 524
GYA+ GAAA +GAV+HT+STA++ FELTGQI H LP+++AV+ AN +AQS QPS YD I
Sbjct: 523 GYAVIGAAALTGAVSHTVSTAVICFELTGQIAHILPMMVAVILANMVAQSLQPSLYDSII 582
Query: 525 IVKKLPYLPRILGRNIGSHHVRVEHFMNHSITTLAKDTPLEEVVKVVTSTDVTEYPLVES 584
VKKLPYLP + + + + VE M + ++ E+ ++ +T V PLV+S
Sbjct: 583 QVKKLPYLPDLGWNQLSKYTIFVEDIMVRDVKFVSASYTYGELRTLLQTTTVKTLPLVDS 642
Query: 585 TESQILVGIVQRAQLVQALQ 604
+S IL+G V+R++L LQ
Sbjct: 643 KDSMILLGSVERSELQALLQ 662
Score = 43.1 bits (100), Expect = 8e-04
Identities = 23/67 (34%), Positives = 34/67 (50%)
Query: 615 QQCLQDILARGCPTEPVTLTLFSETTLHQAQNLFKLLNLQSLFVTSRGRAVGCVSWVEMK 674
+Q Q + C + L +TTLH+ LF LL L +VTS G+ G ++ E++
Sbjct: 808 EQLSQPVCFDSCCIDQSPFQLVEQTTLHKTHTLFSLLGLHLAYVTSMGKLRGVLALEELQ 867
Query: 675 KAISNLT 681
KAI T
Sbjct: 868 KAIEGHT 874
>gi|153252026 chloride channel 4 [Homo sapiens]
Length = 760
Score = 193 bits (491), Expect = 4e-49
Identities = 171/640 (26%), Positives = 290/640 (45%), Gaps = 73/640 (11%)
Query: 84 EIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGGSGIPELKTMLAGVILEDYLDIKN 143
E +++L YL + ++ + + + P + GSGIPE+KT+L+G I+ YL
Sbjct: 144 EGASAYILNYLMYILWALLFAFLAVSLVRVFAPYACGSGIPEIKTILSGFIIRGYLGKWT 203
Query: 144 FGAKVVGLSCTLATGSTLFLGKVGPFVHLSVMIAAYLGRVRTTTIGEPENKSKQNEMLVA 203
K V L +++G L LGK GP VH++ + + + +N+ K+ E+L A
Sbjct: 204 LLIKTVTLVLVVSSG--LSLGKEGPLVHVACCCGNFFSSLFSKY---SKNEGKRREVLSA 258
Query: 204 AAAVGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGFFAATCGAFIFRLLAVFNSEQETI 263
AAA GV+ F AP GVLFS+E +S +F ++ WR FFAA AF R + F + +
Sbjct: 259 AAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTLRSINPFGNSR--- 315
Query: 264 TSLYKTSFRVDVPFDLPEIFFFVALGGICGVLSCAYLFCQRTFLSFIKTNRYSSKLLATS 323
L P+ + E+F F+ LG G+ ++ C + KT R
Sbjct: 316 --LVLFYVEYHTPWYMAELFPFILLGVFGGLWGTLFIRCNIAWCRRRKTTRLG------K 367
Query: 324 KPVYSAL-ATLLLASITYPPGVGHFLASRLSMKQHLDSLFDN----HSWALMTQNSSPPW 378
PV + T + A I YP +R S + + LF++ S L + P
Sbjct: 368 YPVLEVIVVTAITAIIAYPNPY-----TRQSTSELISELFNDCGALESSQLCDYINDPNM 422
Query: 379 PEELD-----PQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIPMPAGYFMPIFILG 433
+D P + +T LA L+ K + I + +P+G F+P +G
Sbjct: 423 TRPVDDIPDRPAGV------GVYTAMWQLALALIFKIVVTIFTFGMKIPSGLFIPSMAVG 476
Query: 434 AAIGRLLG---EALAVAFPEGIVTGGVTNP----IMPGGYALAGAAAFSGAVTH-TISTA 485
A GR++G E LA + I+ P + PG YA+ GAAA G VT T+S
Sbjct: 477 AIAGRMVGIGVEQLAYHHHDWIIFRNWCRPGADCVTPGLYAMVGAAACLGGVTRMTVSLV 536
Query: 486 LLAFELTGQIVHALPVLMAVLAANAIAQSC-QPSFYDGTIIVKKLPYL---PRILGRNIG 541
++ FELTG + + +P++ A + + +A + + Y+ I + P+L R +
Sbjct: 537 VIMFELTGGLEYIVPLMAAAVTSKWVADAFGKEGIYEAHIHLNGYPFLDVKDEFTHRTLA 596
Query: 542 SHHVRVEHFMNHSITTLAKDT-PLEEVVKVVTSTDVTEYPLVESTESQILVGIVQRAQLV 600
+ +R ++ L +D+ +E+V ++ TD +P+V S +S+ L+G QR +L+
Sbjct: 597 TDVMRPRR-GEPPLSVLTQDSMTVEDVETLIKETDYNGFPVVVSRDSERLIGFAQRRELI 655
Query: 601 QALQ------------------AEPPSRAPGHQQCLQDILARGCPTEPVTLTLFSETTLH 642
A++ EPP L+ L R P T+T T +
Sbjct: 656 LAIKNARQRQEGIVSNSIMYFTEEPPELPANSPHPLK--LRRILNLSPFTVT--DHTPME 711
Query: 643 QAQNLFKLLNLQSLFVTSRGRAVGCVSWVEMKKAISNLTN 682
++F+ L L+ VT GR +G ++ ++ + ++ + N
Sbjct: 712 TVVDIFRKLGLRQCLVTRSGRLLGIITKKDVLRHMAQMAN 751
>gi|189217923 chloride channel 5 isoform a [Homo sapiens]
Length = 816
Score = 187 bits (475), Expect = 3e-47
Identities = 174/646 (26%), Positives = 287/646 (44%), Gaps = 94/646 (14%)
Query: 88 SHLLRYLSWTVYPVALVSFSSGFSQSITPSSGGSGIPELKTMLAGVILEDYLDIKNFGAK 147
++++ Y + ++ + + + P + GSGIPE+KT+L+G I+ YL K
Sbjct: 205 AYIVNYFMYVLWALLFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLVIK 264
Query: 148 VVGLSCTLATGSTLFLGKVGPFVHLSVMIAAYLGRVRTTTIGE-PENKSKQNEMLVAAAA 206
+ L LA S L LGK GP VH +A G + + +N++K+ E+L AAAA
Sbjct: 265 TITL--VLAVSSGLSLGKEGPLVH----VACCCGNILCHCFNKYRKNEAKRREVLSAAAA 318
Query: 207 VGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGFFAATCGAFIFRLLAVFNSEQETITSL 266
GV+ F AP GVLFS+E +S +F ++ WR FFAA AF R + F + + L
Sbjct: 319 AGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTLRSINPFGNSR---LVL 375
Query: 267 YKTSFRVDVPFDLPEIFFFVAL---GGICGVLSCAYLFCQRTFLSFIKTN-RYSSKLLAT 322
+ F P+ L E+ F+ L GG+ G L FI+TN + K T
Sbjct: 376 FYVEFH--TPWHLFELVPFILLGIFGGLWGAL-------------FIRTNIAWCRKRKTT 420
Query: 323 SKPVYSALATLLLASIT----YPPGVGHFLASRLSMKQHLDSLFDN-------------H 365
Y + L++ +IT +P +R+S + + LF++ +
Sbjct: 421 QLGKYPVIEVLVVTAITAILAFPNEY-----TRMSTSELISELFNDCGLLDSSKLCDYEN 475
Query: 366 SWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIPMPAGY 425
+ P P + W+ LA L++K + I + +P+G
Sbjct: 476 RFNTSKGGELPDRPAGVGVYSAMWQ-----------LALTLILKIVITIFTFGMKIPSGL 524
Query: 426 FMPIFILGAAIGRLLG---EALAVAFPEGIVTGGVTNP----IMPGGYALAGAAAFSGAV 478
F+P +GA GRLLG E LA E V + I PG YA+ GAAA G V
Sbjct: 525 FIPSMAVGAIAGRLLGVGMEQLAYYHQEWTVFNSWCSQGADCITPGLYAMVGAAACLGGV 584
Query: 479 TH-TISTALLAFELTGQIVHALPVLMAVLAANAIAQSC-QPSFYDGTIIVKKLPYLPRIL 536
T T+S ++ FELTG + + +P++ A + + +A + + YD I + P+L
Sbjct: 585 TRMTVSLVVIMFELTGGLEYIVPLMAAAMTSKWVADALGREGIYDAHIRLNGYPFLE--- 641
Query: 537 GRNIGSHHVRVEHFM-----NHSITTLAKDT-PLEEVVKVVTSTDVTEYPLVESTESQIL 590
+ +H M + +T L +D+ +E+V +++ T + +P+V S ESQ L
Sbjct: 642 AKEEFAHKTLAMDVMKPRRNDPLLTVLTQDSMTVEDVETIISETTYSGFPVVVSRESQRL 701
Query: 591 VGIVQRAQLVQALQAEPPSRAPGHQQCLQDILARGCPTEPVT--------------LTLF 636
VG V R L+ +++ + + P P T T+
Sbjct: 702 VGFVLRRDLIISIENARKKQDGVVSTSIIYFTEHSPPLPPYTPPTLKLRNILDLSPFTVT 761
Query: 637 SETTLHQAQNLFKLLNLQSLFVTSRGRAVGCVSWVEMKKAISNLTN 682
T + ++F+ L L+ VT GR +G ++ ++ K I+ + N
Sbjct: 762 DLTPMEIVVDIFRKLGLRQCLVTHNGRLLGIITKKDVLKHIAQMAN 807
>gi|189217921 chloride channel 5 isoform a [Homo sapiens]
Length = 816
Score = 187 bits (475), Expect = 3e-47
Identities = 174/646 (26%), Positives = 287/646 (44%), Gaps = 94/646 (14%)
Query: 88 SHLLRYLSWTVYPVALVSFSSGFSQSITPSSGGSGIPELKTMLAGVILEDYLDIKNFGAK 147
++++ Y + ++ + + + P + GSGIPE+KT+L+G I+ YL K
Sbjct: 205 AYIVNYFMYVLWALLFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLVIK 264
Query: 148 VVGLSCTLATGSTLFLGKVGPFVHLSVMIAAYLGRVRTTTIGE-PENKSKQNEMLVAAAA 206
+ L LA S L LGK GP VH +A G + + +N++K+ E+L AAAA
Sbjct: 265 TITL--VLAVSSGLSLGKEGPLVH----VACCCGNILCHCFNKYRKNEAKRREVLSAAAA 318
Query: 207 VGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGFFAATCGAFIFRLLAVFNSEQETITSL 266
GV+ F AP GVLFS+E +S +F ++ WR FFAA AF R + F + + L
Sbjct: 319 AGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTLRSINPFGNSR---LVL 375
Query: 267 YKTSFRVDVPFDLPEIFFFVAL---GGICGVLSCAYLFCQRTFLSFIKTN-RYSSKLLAT 322
+ F P+ L E+ F+ L GG+ G L FI+TN + K T
Sbjct: 376 FYVEFH--TPWHLFELVPFILLGIFGGLWGAL-------------FIRTNIAWCRKRKTT 420
Query: 323 SKPVYSALATLLLASIT----YPPGVGHFLASRLSMKQHLDSLFDN-------------H 365
Y + L++ +IT +P +R+S + + LF++ +
Sbjct: 421 QLGKYPVIEVLVVTAITAILAFPNEY-----TRMSTSELISELFNDCGLLDSSKLCDYEN 475
Query: 366 SWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIPMPAGY 425
+ P P + W+ LA L++K + I + +P+G
Sbjct: 476 RFNTSKGGELPDRPAGVGVYSAMWQ-----------LALTLILKIVITIFTFGMKIPSGL 524
Query: 426 FMPIFILGAAIGRLLG---EALAVAFPEGIVTGGVTNP----IMPGGYALAGAAAFSGAV 478
F+P +GA GRLLG E LA E V + I PG YA+ GAAA G V
Sbjct: 525 FIPSMAVGAIAGRLLGVGMEQLAYYHQEWTVFNSWCSQGADCITPGLYAMVGAAACLGGV 584
Query: 479 TH-TISTALLAFELTGQIVHALPVLMAVLAANAIAQSC-QPSFYDGTIIVKKLPYLPRIL 536
T T+S ++ FELTG + + +P++ A + + +A + + YD I + P+L
Sbjct: 585 TRMTVSLVVIMFELTGGLEYIVPLMAAAMTSKWVADALGREGIYDAHIRLNGYPFLE--- 641
Query: 537 GRNIGSHHVRVEHFM-----NHSITTLAKDT-PLEEVVKVVTSTDVTEYPLVESTESQIL 590
+ +H M + +T L +D+ +E+V +++ T + +P+V S ESQ L
Sbjct: 642 AKEEFAHKTLAMDVMKPRRNDPLLTVLTQDSMTVEDVETIISETTYSGFPVVVSRESQRL 701
Query: 591 VGIVQRAQLVQALQAEPPSRAPGHQQCLQDILARGCPTEPVT--------------LTLF 636
VG V R L+ +++ + + P P T T+
Sbjct: 702 VGFVLRRDLIISIENARKKQDGVVSTSIIYFTEHSPPLPPYTPPTLKLRNILDLSPFTVT 761
Query: 637 SETTLHQAQNLFKLLNLQSLFVTSRGRAVGCVSWVEMKKAISNLTN 682
T + ++F+ L L+ VT GR +G ++ ++ K I+ + N
Sbjct: 762 DLTPMEIVVDIFRKLGLRQCLVTHNGRLLGIITKKDVLKHIAQMAN 807
>gi|4557473 chloride channel 5 isoform b [Homo sapiens]
Length = 746
Score = 187 bits (475), Expect = 3e-47
Identities = 174/646 (26%), Positives = 287/646 (44%), Gaps = 94/646 (14%)
Query: 88 SHLLRYLSWTVYPVALVSFSSGFSQSITPSSGGSGIPELKTMLAGVILEDYLDIKNFGAK 147
++++ Y + ++ + + + P + GSGIPE+KT+L+G I+ YL K
Sbjct: 135 AYIVNYFMYVLWALLFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLVIK 194
Query: 148 VVGLSCTLATGSTLFLGKVGPFVHLSVMIAAYLGRVRTTTIGE-PENKSKQNEMLVAAAA 206
+ L LA S L LGK GP VH +A G + + +N++K+ E+L AAAA
Sbjct: 195 TITL--VLAVSSGLSLGKEGPLVH----VACCCGNILCHCFNKYRKNEAKRREVLSAAAA 248
Query: 207 VGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGFFAATCGAFIFRLLAVFNSEQETITSL 266
GV+ F AP GVLFS+E +S +F ++ WR FFAA AF R + F + + L
Sbjct: 249 AGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTLRSINPFGNSR---LVL 305
Query: 267 YKTSFRVDVPFDLPEIFFFVAL---GGICGVLSCAYLFCQRTFLSFIKTN-RYSSKLLAT 322
+ F P+ L E+ F+ L GG+ G L FI+TN + K T
Sbjct: 306 FYVEFH--TPWHLFELVPFILLGIFGGLWGAL-------------FIRTNIAWCRKRKTT 350
Query: 323 SKPVYSALATLLLASIT----YPPGVGHFLASRLSMKQHLDSLFDN-------------H 365
Y + L++ +IT +P +R+S + + LF++ +
Sbjct: 351 QLGKYPVIEVLVVTAITAILAFPNEY-----TRMSTSELISELFNDCGLLDSSKLCDYEN 405
Query: 366 SWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIPMPAGY 425
+ P P + W+ LA L++K + I + +P+G
Sbjct: 406 RFNTSKGGELPDRPAGVGVYSAMWQ-----------LALTLILKIVITIFTFGMKIPSGL 454
Query: 426 FMPIFILGAAIGRLLG---EALAVAFPEGIVTGGVTNP----IMPGGYALAGAAAFSGAV 478
F+P +GA GRLLG E LA E V + I PG YA+ GAAA G V
Sbjct: 455 FIPSMAVGAIAGRLLGVGMEQLAYYHQEWTVFNSWCSQGADCITPGLYAMVGAAACLGGV 514
Query: 479 TH-TISTALLAFELTGQIVHALPVLMAVLAANAIAQSC-QPSFYDGTIIVKKLPYLPRIL 536
T T+S ++ FELTG + + +P++ A + + +A + + YD I + P+L
Sbjct: 515 TRMTVSLVVIMFELTGGLEYIVPLMAAAMTSKWVADALGREGIYDAHIRLNGYPFLE--- 571
Query: 537 GRNIGSHHVRVEHFM-----NHSITTLAKDT-PLEEVVKVVTSTDVTEYPLVESTESQIL 590
+ +H M + +T L +D+ +E+V +++ T + +P+V S ESQ L
Sbjct: 572 AKEEFAHKTLAMDVMKPRRNDPLLTVLTQDSMTVEDVETIISETTYSGFPVVVSRESQRL 631
Query: 591 VGIVQRAQLVQALQAEPPSRAPGHQQCLQDILARGCPTEPVT--------------LTLF 636
VG V R L+ +++ + + P P T T+
Sbjct: 632 VGFVLRRDLIISIENARKKQDGVVSTSIIYFTEHSPPLPPYTPPTLKLRNILDLSPFTVT 691
Query: 637 SETTLHQAQNLFKLLNLQSLFVTSRGRAVGCVSWVEMKKAISNLTN 682
T + ++F+ L L+ VT GR +G ++ ++ K I+ + N
Sbjct: 692 DLTPMEIVVDIFRKLGLRQCLVTHNGRLLGIITKKDVLKHIAQMAN 737
>gi|55770838 chloride channel 3 isoform b [Homo sapiens]
Length = 818
Score = 178 bits (452), Expect = 1e-44
Identities = 165/643 (25%), Positives = 281/643 (43%), Gaps = 87/643 (13%)
Query: 88 SHLLRYLSWTVYPVALVSFSSGFSQSITPSSGGSGIPELKTMLAGVILEDYLDIKNFGAK 147
S+++ Y+ + + ++ + + P + GSGIPE+KT+L+G I+ YL K
Sbjct: 206 SYIMNYIMYIFWALSFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIK 265
Query: 148 VVGLSCTLATGSTLFLGKVGPFVHLSVM---IAAYLGRVRTTTIGEPENKSKQNEMLVAA 204
+ L LA S L LGK GP VH++ I +YL +T N++K+ E+L AA
Sbjct: 266 TITL--VLAVASGLSLGKEGPLVHVACCCGNIFSYLFPKYST------NEAKKREVLSAA 317
Query: 205 AAVGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGFFAATCGAFIFRLLAVFNSEQETIT 264
+A GV+ F AP GVLFS+E +S +F ++ WR FFAA AF+ R + F + +
Sbjct: 318 SAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFVLRSINPFGNSR---- 373
Query: 265 SLYKTSFRVDVPFDLPEIFFFVALGGICGVLSCAYLFCQRTFLSFIKTNRYSSKLLATSK 324
L P+ L E+F F+ LG G+ ++ + K+ ++
Sbjct: 374 -LVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIRANIAWCRRRKSTKFGK------- 425
Query: 325 PVYSALATLLLASIT----YPPGVGHFLASRLSMKQHLD-------SLFD--NHSWALMT 371
Y L +++A+IT +P S L + D SL D N A
Sbjct: 426 --YPVLEVIIVAAITAVIAFPNPYTRLNTSELIKELFTDCGPLESSSLCDYRNDMNASKI 483
Query: 372 QNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIPMPAGYFMPIFI 431
+ P P + W+ L L+ K M + I +P+G F+P
Sbjct: 484 VDDIPDRPAGIGVYSAIWQ-----------LCLALIFKIIMTVFTFGIKVPSGLFIPSMA 532
Query: 432 LGAAIGRLLGEALA---------VAFPEGIVTGGVTNPIMPGGYALAGAAAFSGAVTH-T 481
+GA GR++G A+ F E G + I PG YA+ GAAA G VT T
Sbjct: 533 IGAIAGRIVGIAVEQLAYYHHDWFIFKEWCEVG--ADCITPGLYAMVGAAACLGGVTRMT 590
Query: 482 ISTALLAFELTGQIVHALPVLMAVLAANAIAQSC-QPSFYDGTIIVKKLPYLPRILGRNI 540
+S ++ FELTG + + +P++ AV+ + + + + Y+ I + P+L +
Sbjct: 591 VSLVVIVFELTGGLEYIVPLMAAVMTSKWVGDAFGREGIYEAHIRLNGYPFLD---AKEE 647
Query: 541 GSHHVRVEHFM-----NHSITTLAKDT-PLEEVVKVVTSTDVTEYPLVESTESQILVGIV 594
+H M + + L +D ++++ ++ T +P++ S ESQ LVG
Sbjct: 648 FTHTTLAADVMRPRRNDPPLAVLTQDNMTVDDIENMINETSYNGFPVIMSKESQRLVGFA 707
Query: 595 QRAQLVQALQAEPPSRAPGHQQCLQDILARGCPTEPV---------------TLTLFSET 639
R L A+++ + G + A+ P+ P T+ T
Sbjct: 708 LRRDLTIAIES-ARKKQEGIVGSSRVCFAQHTPSLPAESPRPLKLRSILDMSPFTVTDHT 766
Query: 640 TLHQAQNLFKLLNLQSLFVTSRGRAVGCVSWVEMKKAISNLTN 682
+ ++F+ L L+ VT GR +G ++ ++ + ++ N
Sbjct: 767 PMEIVVDIFRKLGLRQCLVTHNGRLLGIITKKDILRHMAQTAN 809
>gi|55770840 chloride channel 3 isoform e [Homo sapiens]
Length = 866
Score = 174 bits (442), Expect = 2e-43
Identities = 163/630 (25%), Positives = 274/630 (43%), Gaps = 87/630 (13%)
Query: 88 SHLLRYLSWTVYPVALVSFSSGFSQSITPSSGGSGIPELKTMLAGVILEDYLDIKNFGAK 147
S+++ Y+ + + ++ + + P + GSGIPE+KT+L+G I+ YL K
Sbjct: 206 SYIMNYIMYIFWALSFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIK 265
Query: 148 VVGLSCTLATGSTLFLGKVGPFVHLSVM---IAAYLGRVRTTTIGEPENKSKQNEMLVAA 204
+ L LA S L LGK GP VH++ I +YL +T N++K+ E+L AA
Sbjct: 266 TITL--VLAVASGLSLGKEGPLVHVACCCGNIFSYLFPKYST------NEAKKREVLSAA 317
Query: 205 AAVGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGFFAATCGAFIFRLLAVFNSEQETIT 264
+A GV+ F AP GVLFS+E +S +F ++ WR FFAA AF+ R + F + +
Sbjct: 318 SAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFVLRSINPFGNSR---- 373
Query: 265 SLYKTSFRVDVPFDLPEIFFFVALGGICGVLSCAYLFCQRTFLSFIKTNRYSSKLLATSK 324
L P+ L E+F F+ LG G+ ++ + K+ ++
Sbjct: 374 -LVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIRANIAWCRRRKSTKFGK------- 425
Query: 325 PVYSALATLLLASIT----YPPGVGHFLASRLSMKQHLD-------SLFD--NHSWALMT 371
Y L +++A+IT +P S L + D SL D N A
Sbjct: 426 --YPVLEVIIVAAITAVIAFPNPYTRLNTSELIKELFTDCGPLESSSLCDYRNDMNASKI 483
Query: 372 QNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIPMPAGYFMPIFI 431
+ P P + W+ L L+ K M + I +P+G F+P
Sbjct: 484 VDDIPDRPAGIGVYSAIWQ-----------LCLALIFKIIMTVFTFGIKVPSGLFIPSMA 532
Query: 432 LGAAIGRLLGEALA---------VAFPEGIVTGGVTNPIMPGGYALAGAAAFSGAVTH-T 481
+GA GR++G A+ F E G + I PG YA+ GAAA G VT T
Sbjct: 533 IGAIAGRIVGIAVEQLAYYHHDWFIFKEWCEVG--ADCITPGLYAMVGAAACLGGVTRMT 590
Query: 482 ISTALLAFELTGQIVHALPVLMAVLAANAIAQSC-QPSFYDGTIIVKKLPYLPRILGRNI 540
+S ++ FELTG + + +P++ AV+ + + + + Y+ I + P+L +
Sbjct: 591 VSLVVIVFELTGGLEYIVPLMAAVMTSKWVGDAFGREGIYEAHIRLNGYPFLD---AKEE 647
Query: 541 GSHHVRVEHFM-----NHSITTLAKDT-PLEEVVKVVTSTDVTEYPLVESTESQILVGIV 594
+H M + + L +D ++++ ++ T +P++ S ESQ LVG
Sbjct: 648 FTHTTLAADVMRPRRNDPPLAVLTQDNMTVDDIENMINETSYNGFPVIMSKESQRLVGFA 707
Query: 595 QRAQLVQALQAEPPSRAPGHQQCLQDILARGCPTEPV---------------TLTLFSET 639
R L A+++ + G + A+ P+ P T+ T
Sbjct: 708 LRRDLTIAIES-ARKKQEGIVGSSRVCFAQHTPSLPAESPRPLKLRSILDMSPFTVTDHT 766
Query: 640 TLHQAQNLFKLLNLQSLFVTSRGRAVGCVS 669
+ ++F+ L L+ VT G +G ++
Sbjct: 767 PMEIVVDIFRKLGLRQCLVTHNGIVLGIIT 796
>gi|167466160 chloride channel 7 isoform b [Homo sapiens]
Length = 781
Score = 147 bits (371), Expect = 3e-35
Identities = 166/686 (24%), Positives = 292/686 (42%), Gaps = 95/686 (13%)
Query: 50 WYFLMTLGVLMALVSYAMNFAIGC-------VVRAHQWLYREIGDSHLLRYLSWTVYPVA 102
W +G+L LV+ ++ + V++ + + E G L W A
Sbjct: 103 WVICALIGILTGLVACFIDIVVENLAGLKYRVIKGNIDKFTEKGGLSF-SLLLWATLNAA 161
Query: 103 LVSFSSGFSQSITPSSGGSGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLF 162
V S I P + GSGIP++K L GV + + +K KV G+ ++ G L
Sbjct: 162 FVLVGSVIVAFIEPVAAGSGIPQIKCFLNGVKIPHVVRLKTLVIKVSGVILSVVGG--LA 219
Query: 163 LGKVGPFVHLSVMIAAYLGRVRTTTIGEP-------ENKSKQNEMLVAAAAVGVATVFAA 215
+GK GP +H +IAA + + R+T++ +++ + + A AA GV+ F A
Sbjct: 220 VGKEGPMIHSGSVIAAGISQGRSTSLKRDFKIFEYFRRDTEKRDFVSAGAAAGVSAAFGA 279
Query: 216 PFSGVLFSIEVMSSHFSVRDYWRGFFAATCGAFIFR-LLAVFNSEQETITSLYKTSF-RV 273
P GVLFS+E +S ++ WR FFA+ F +L++++ ++S +F R
Sbjct: 280 PVGGVLFSLEEGASFWNQFLTWRIFFASMISTFTLNFVLSIYHGNMWDLSSPGLINFGRF 339
Query: 274 D---VPFDLPEIFFFVALGGICGVLSCAYLFCQRTFLSFIKTNRYSSKLLATSKPVYSAL 330
D + + + EI F+A+G + GVL + F ++ +P +
Sbjct: 340 DSEKMAYTIHEIPVFIAMGVVGGVLGAVFNALNYWLTMF--------RIRYIHRPCLQVI 391
Query: 331 ATLLLASITYPPGVGHFLASR-------LSMKQHLDSLF--DNHSWALMTQNSSPPWPEE 381
+L+A++T +SR SM L LF D ++ + P
Sbjct: 392 EAVLVAAVTATVAFVLIYSSRDCQPLQGGSMSYPL-QLFCADGEYNSMAAAFFNTPEKSV 450
Query: 382 LDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIPMPAGYFMPIFILGAAIGRLLG 441
+ H Y+P TL F ++ F++ + + AG F+P ++GAA GRL G
Sbjct: 451 VSLFHDPPGSYNPL-----TLGLFTLVYFFLACWTYGLTVSAGVFIPSLLIGAAWGRLFG 505
Query: 442 EALAVAFPEGIVTGGVTNPIMPGGYALAGAAA-FSGAVTHTISTALLAFELTGQIVHALP 500
+L+ I PG YAL GAAA G V T+S ++ E T + + P
Sbjct: 506 ISLSYLTGAAIWAD-------PGKYALMGAAAQLGGIVRMTLSLTVIMMEATSNVTYGFP 558
Query: 501 VLMAVLAANAIAQSCQPSFYDGTIIVKKLPYLPRILGRNIGSHHVRVEHFMNHSITTLAK 560
+++ ++ A + YD I ++ +P+L + SH + M+ +T L +
Sbjct: 559 IMLVLMTAKIVGDVFIEGLYDMHIQLQSVPFLH--WEAPVTSHSLTAREVMSTPVTCLRR 616
Query: 561 DTPLEEVVKVV--TSTDVTEYPLVE---STESQILVGIVQRAQLVQALQAE--------- 606
+ +V V+ T+++ +P+VE T+ L G++ R+QL+ L+ +
Sbjct: 617 REKVGVIVDVLSDTASNHNGFPVVEHADDTQPARLQGLILRSQLIVLLKHKVFVERSNLG 676
Query: 607 ------------------PPSR----APGHQQCLQDILARGCPTEPVTLTLFSETTLHQA 644
PP + + ++C D+ P T+ E +L +
Sbjct: 677 LVQRRLRLKDFRDAYPRFPPIQSIHVSQDERECTMDLSEF---MNPSPYTVPQEASLPRV 733
Query: 645 QNLFKLLNLQSLFVT-SRGRAVGCVS 669
LF+ L L+ L V +R + VG V+
Sbjct: 734 FKLFRALGLRHLVVVDNRNQVVGLVT 759
>gi|14149607 chloride channel 7 isoform a [Homo sapiens]
Length = 805
Score = 147 bits (371), Expect = 3e-35
Identities = 166/686 (24%), Positives = 292/686 (42%), Gaps = 95/686 (13%)
Query: 50 WYFLMTLGVLMALVSYAMNFAIGC-------VVRAHQWLYREIGDSHLLRYLSWTVYPVA 102
W +G+L LV+ ++ + V++ + + E G L W A
Sbjct: 127 WVICALIGILTGLVACFIDIVVENLAGLKYRVIKGNIDKFTEKGGLSF-SLLLWATLNAA 185
Query: 103 LVSFSSGFSQSITPSSGGSGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLF 162
V S I P + GSGIP++K L GV + + +K KV G+ ++ G L
Sbjct: 186 FVLVGSVIVAFIEPVAAGSGIPQIKCFLNGVKIPHVVRLKTLVIKVSGVILSVVGG--LA 243
Query: 163 LGKVGPFVHLSVMIAAYLGRVRTTTIGEP-------ENKSKQNEMLVAAAAVGVATVFAA 215
+GK GP +H +IAA + + R+T++ +++ + + A AA GV+ F A
Sbjct: 244 VGKEGPMIHSGSVIAAGISQGRSTSLKRDFKIFEYFRRDTEKRDFVSAGAAAGVSAAFGA 303
Query: 216 PFSGVLFSIEVMSSHFSVRDYWRGFFAATCGAFIFR-LLAVFNSEQETITSLYKTSF-RV 273
P GVLFS+E +S ++ WR FFA+ F +L++++ ++S +F R
Sbjct: 304 PVGGVLFSLEEGASFWNQFLTWRIFFASMISTFTLNFVLSIYHGNMWDLSSPGLINFGRF 363
Query: 274 D---VPFDLPEIFFFVALGGICGVLSCAYLFCQRTFLSFIKTNRYSSKLLATSKPVYSAL 330
D + + + EI F+A+G + GVL + F ++ +P +
Sbjct: 364 DSEKMAYTIHEIPVFIAMGVVGGVLGAVFNALNYWLTMF--------RIRYIHRPCLQVI 415
Query: 331 ATLLLASITYPPGVGHFLASR-------LSMKQHLDSLF--DNHSWALMTQNSSPPWPEE 381
+L+A++T +SR SM L LF D ++ + P
Sbjct: 416 EAVLVAAVTATVAFVLIYSSRDCQPLQGGSMSYPL-QLFCADGEYNSMAAAFFNTPEKSV 474
Query: 382 LDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIPMPAGYFMPIFILGAAIGRLLG 441
+ H Y+P TL F ++ F++ + + AG F+P ++GAA GRL G
Sbjct: 475 VSLFHDPPGSYNPL-----TLGLFTLVYFFLACWTYGLTVSAGVFIPSLLIGAAWGRLFG 529
Query: 442 EALAVAFPEGIVTGGVTNPIMPGGYALAGAAA-FSGAVTHTISTALLAFELTGQIVHALP 500
+L+ I PG YAL GAAA G V T+S ++ E T + + P
Sbjct: 530 ISLSYLTGAAIWAD-------PGKYALMGAAAQLGGIVRMTLSLTVIMMEATSNVTYGFP 582
Query: 501 VLMAVLAANAIAQSCQPSFYDGTIIVKKLPYLPRILGRNIGSHHVRVEHFMNHSITTLAK 560
+++ ++ A + YD I ++ +P+L + SH + M+ +T L +
Sbjct: 583 IMLVLMTAKIVGDVFIEGLYDMHIQLQSVPFLH--WEAPVTSHSLTAREVMSTPVTCLRR 640
Query: 561 DTPLEEVVKVV--TSTDVTEYPLVE---STESQILVGIVQRAQLVQALQAE--------- 606
+ +V V+ T+++ +P+VE T+ L G++ R+QL+ L+ +
Sbjct: 641 REKVGVIVDVLSDTASNHNGFPVVEHADDTQPARLQGLILRSQLIVLLKHKVFVERSNLG 700
Query: 607 ------------------PPSR----APGHQQCLQDILARGCPTEPVTLTLFSETTLHQA 644
PP + + ++C D+ P T+ E +L +
Sbjct: 701 LVQRRLRLKDFRDAYPRFPPIQSIHVSQDERECTMDLSEF---MNPSPYTVPQEASLPRV 757
Query: 645 QNLFKLLNLQSLFVT-SRGRAVGCVS 669
LF+ L L+ L V +R + VG V+
Sbjct: 758 FKLFRALGLRHLVVVDNRNQVVGLVT 783
>gi|4502873 chloride channel 6 isoform ClC-6a [Homo sapiens]
Length = 869
Score = 119 bits (299), Expect = 7e-27
Identities = 125/516 (24%), Positives = 220/516 (42%), Gaps = 76/516 (14%)
Query: 114 ITPSSGGSGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLFLGKVGPFVHLS 173
I P + GSGIPE+K L GV + + ++ KV+G+ ++A G LF+GK GP +H
Sbjct: 150 IEPVAAGSGIPEVKCYLNGVKVPGIVRLRTLLCKVLGVLFSVAGG--LFVGKEGPMIHSG 207
Query: 174 VMIAAYLGRVRTTTIGEPE-------NKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEV 226
++ A L + ++ ++ + + + + + + A AA GVA F AP G LFS+E
Sbjct: 208 SVVGAGLPQFQSISLRKIQFNFPYFRSDRDKRDFVSAGAAAGVAAAFGAPIGGTLFSLEE 267
Query: 227 MSSHFSVRDYWRGFFAATCGAFI---------------FRLLAVFNSEQETITSLYKTSF 271
SS ++ W+ F + F F+L + N + + K
Sbjct: 268 GSSFWNQGLTWKVLFCSMSATFTLNFFRSGIQFGSWGSFQLPGLLNFGEFKCSDSDKKCH 327
Query: 272 RVDVPFDLPEIFFFVALGGICGVLSCAYLFCQRTFLSFIKTNRYSSKLLATSKPVYSALA 331
+ ++ FFV +G I G+L + + + +Y + + + L
Sbjct: 328 L----WTAMDLGFFVVMGVIGGLLGATFNCLNK------RLAKYRMRNVHPKPKLVRVLE 377
Query: 332 TLLLASITYPPGVGHFLASRL---SMKQHLDSLFDNHSWAL-MTQNSSPPWPEELDPQHL 387
+LL++ +T V F+AS + + S N S+ L +T++ + P
Sbjct: 378 SLLVSLVT---TVVVFVASMVLGECRQMSSSSQIGNDSFQLQVTEDVNSSIKTFFCPN-- 432
Query: 388 WWEWYHPRFTIF--------------------GTLAFFLVMKFWMLILATTIPMPAGYFM 427
+ Y+ T+F TLA F V+ F + I +P+G F+
Sbjct: 433 --DTYNDMATLFFNPQESAILQLFHQDGTFSPVTLALFFVLYFLLACWTYGISVPSGLFV 490
Query: 428 PIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIMPGGYALAGAAAFSGAVTH-TISTAL 486
P + GAA GRL+ L G I G +AL GAAAF G V TIS +
Sbjct: 491 PSLLCGAAFGRLVANVLKSYIGLG--------HIYSGTFALIGAAAFLGGVVRMTISLTV 542
Query: 487 LAFELTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTIIVKKLPYLPRILGRNIGSHHVR 546
+ E T +I + LP+++ ++ A YD + ++ +P L + +R
Sbjct: 543 ILIESTNEITYGLPIMVTLMVAKWTGDFFNKGIYDIHVGLRGVPLLE--WETEVEMDKLR 600
Query: 547 VEHFMNHSITTLAKDTPLEEVVKVVTSTDVTEYPLV 582
M ++T + T ++ +V ++ +T +P+V
Sbjct: 601 ASDIMEPNLTYVYPHTRIQSLVSILRTTVHHAFPVV 636
>gi|12025671 chloride channel 6 isoform ClC-6c [Homo sapiens]
Length = 353
Score = 72.8 bits (177), Expect = 1e-12
Identities = 45/142 (31%), Positives = 75/142 (52%), Gaps = 9/142 (6%)
Query: 114 ITPSSGGSGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLFLGKVGPFVHLS 173
I P + GSGIPE+K L GV + + ++ KV+G+ ++A G LF+GK GP +H
Sbjct: 150 IEPVAAGSGIPEVKCYLNGVKVPGIVRLRTLLCKVLGVLFSVAGG--LFVGKEGPMIHSG 207
Query: 174 VMIAAYLGRVRTTTIGEPE-------NKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEV 226
++ A L + ++ ++ + + + + + + A AA GVA F AP G LFS+E
Sbjct: 208 SVVGAGLPQFQSISLRKIQFNFPYFRSDRDKRDFVSAGAAAGVAAAFGAPIGGTLFSLEE 267
Query: 227 MSSHFSVRDYWRGFFAATCGAF 248
SS ++ W+ F + F
Sbjct: 268 GSSFWNQGLTWKVLFCSMSATF 289
>gi|12025673 chloride channel 6 isoform ClC-6d [Homo sapiens]
Length = 308
Score = 47.8 bits (112), Expect = 3e-05
Identities = 26/75 (34%), Positives = 45/75 (60%), Gaps = 2/75 (2%)
Query: 114 ITPSSGGSGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLFLGKVGPFVHLS 173
I P + GSGIPE+K L GV + + ++ KV+G+ ++A G LF+GK GP +H
Sbjct: 150 IEPVAAGSGIPEVKCYLNGVKVPGIVRLRTLLCKVLGVLFSVAGG--LFVGKEGPMIHSG 207
Query: 174 VMIAAYLGRVRTTTI 188
++ A L + ++ ++
Sbjct: 208 SVVGAGLPQFQSISL 222
>gi|12025668 chloride channel 6 isoform ClC-6b [Homo sapiens]
Length = 320
Score = 47.8 bits (112), Expect = 3e-05
Identities = 26/75 (34%), Positives = 45/75 (60%), Gaps = 2/75 (2%)
Query: 114 ITPSSGGSGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLFLGKVGPFVHLS 173
I P + GSGIPE+K L GV + + ++ KV+G+ ++A G LF+GK GP +H
Sbjct: 150 IEPVAAGSGIPEVKCYLNGVKVPGIVRLRTLLCKVLGVLFSVAGG--LFVGKEGPMIHSG 207
Query: 174 VMIAAYLGRVRTTTI 188
++ A L + ++ ++
Sbjct: 208 SVVGAGLPQFQSISL 222
>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
Length = 4374
Score = 31.2 bits (69), Expect = 3.3
Identities = 18/48 (37%), Positives = 27/48 (56%)
Query: 113 SITPSSGGSGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGST 160
++T SSG +G L T+L I+ED +++ KVV + T GST
Sbjct: 1806 NLTQSSGFNGFTPLVTLLLRHIIEDPCTLRHTMEKVVRSAATSGAGST 1853
>gi|126352608 elastin isoform e precursor [Homo sapiens]
Length = 705
Score = 30.8 bits (68), Expect = 4.4
Identities = 20/52 (38%), Positives = 25/52 (48%), Gaps = 6/52 (11%)
Query: 420 PMPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIMPGGYALAGA 471
P+P G + GA +G LG AV FP +V GGV + A AGA
Sbjct: 65 PVPGG------LAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGA 110
>gi|126352446 elastin isoform d precursor [Homo sapiens]
Length = 711
Score = 30.8 bits (68), Expect = 4.4
Identities = 20/52 (38%), Positives = 25/52 (48%), Gaps = 6/52 (11%)
Query: 420 PMPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIMPGGYALAGA 471
P+P G + GA +G LG AV FP +V GGV + A AGA
Sbjct: 65 PVPGG------LAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGA 110
>gi|126352322 elastin isoform c precursor [Homo sapiens]
Length = 692
Score = 30.8 bits (68), Expect = 4.4
Identities = 20/52 (38%), Positives = 25/52 (48%), Gaps = 6/52 (11%)
Query: 420 PMPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIMPGGYALAGA 471
P+P G + GA +G LG AV FP +V GGV + A AGA
Sbjct: 65 PVPGG------LAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGA 110
>gi|126352700 elastin isoform b precursor [Homo sapiens]
Length = 677
Score = 30.8 bits (68), Expect = 4.4
Identities = 20/52 (38%), Positives = 25/52 (48%), Gaps = 6/52 (11%)
Query: 420 PMPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIMPGGYALAGA 471
P+P G + GA +G LG AV FP +V GGV + A AGA
Sbjct: 55 PVPGG------LAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGA 100
>gi|126352440 elastin isoform a precursor [Homo sapiens]
Length = 724
Score = 30.8 bits (68), Expect = 4.4
Identities = 20/52 (38%), Positives = 25/52 (48%), Gaps = 6/52 (11%)
Query: 420 PMPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIMPGGYALAGA 471
P+P G + GA +G LG AV FP +V GGV + A AGA
Sbjct: 65 PVPGG------LAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGA 110
>gi|156938237 ADP-ribosylation factor-like 17 isoform a [Homo
sapiens]
Length = 177
Score = 30.8 bits (68), Expect = 4.4
Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 1/54 (1%)
Query: 194 KSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGFFAATCGA 247
K K E + A VG V + F++ + SHF +R W+ FF T GA
Sbjct: 36 KLKLGETVPAVPTVGFC-VETVEYKNNTFAVWDVGSHFKIRPLWQHFFQNTKGA 88
>gi|166063999 hypothetical protein LOC51326 isoform a [Homo sapiens]
Length = 177
Score = 30.8 bits (68), Expect = 4.4
Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 1/54 (1%)
Query: 194 KSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGFFAATCGA 247
K K E + A VG V + F++ + SHF +R W+ FF T GA
Sbjct: 36 KLKLGETVPAVPTVGFC-VETVEYKNNTFAVWDVGSHFKIRPLWQHFFQNTKGA 88
>gi|83035129 coiled-coil domain containing 108 isoform 1 [Homo
sapiens]
Length = 1925
Score = 30.4 bits (67), Expect = 5.7
Identities = 28/125 (22%), Positives = 48/125 (38%), Gaps = 6/125 (4%)
Query: 569 KVVTSTDVTEYPLVESTESQILVGIVQRAQLVQALQAEPPSRAPGHQQ------CLQDIL 622
++V T E P V S L+ ++ R + VQ QAE S+ H Q C +D++
Sbjct: 8 RLVEKTQKVENPSVSFASSFPLIPLLLRGKSVQKKQAESKSQIKLHTQSAPFGLCPKDMM 67
Query: 623 ARGCPTEPVTLTLFSETTLHQAQNLFKLLNLQSLFVTSRGRAVGCVSWVEMKKAISNLTN 682
P+ V T++ + + + A+ S + + A S T
Sbjct: 68 LTQAPSSVVRSRNSRNHTVNSGGSCLSASTVAIPAINDSSAAMSACSTISAQPASSMDTQ 127
Query: 683 PPAPK 687
+PK
Sbjct: 128 MHSPK 132
>gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo
sapiens]
Length = 1176
Score = 29.6 bits (65), Expect = 9.7
Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 10/59 (16%)
Query: 397 TIFGTLAFFLVMKFWMLI---LATTIPMPAGYFMPIFILGAAIGRLLGEALAVAFPEGI 452
T+ + +F++ FW+ LA P+ YF+ FI+G + L VA PEG+
Sbjct: 384 TVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFFIIGVTV-------LVVAVPEGL 435
>gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo
sapiens]
Length = 1220
Score = 29.6 bits (65), Expect = 9.7
Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 10/59 (16%)
Query: 397 TIFGTLAFFLVMKFWMLI---LATTIPMPAGYFMPIFILGAAIGRLLGEALAVAFPEGI 452
T+ + +F++ FW+ LA P+ YF+ FI+G + L VA PEG+
Sbjct: 384 TVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFFIIGVTV-------LVVAVPEGL 435
>gi|84508631 phosphatidylglycerophosphate synthase 1 [Homo sapiens]
Length = 556
Score = 29.6 bits (65), Expect = 9.7
Identities = 16/63 (25%), Positives = 26/63 (41%)
Query: 246 GAFIFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGICGVLSCAYLFCQRT 305
GA ++ FN Q + + T + PE+ F G+ G + AY+ +R
Sbjct: 379 GAKVYLTTGYFNLTQAYMDLVLGTRAEYQILLASPEVNGFFGAKGVAGAIPAAYVHIERQ 438
Query: 306 FLS 308
F S
Sbjct: 439 FFS 441
>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 2 [Homo sapiens]
Length = 1403
Score = 29.6 bits (65), Expect = 9.7
Identities = 15/32 (46%), Positives = 16/32 (50%), Gaps = 2/32 (6%)
Query: 613 GHQQCLQDILARGCPTEPVTLTLFSETTLHQA 644
GH CLQ +L CPTE L T LH A
Sbjct: 99 GHALCLQKLLQYNCPTEHADLQ--GRTALHDA 128
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.138 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,218,675
Number of Sequences: 37866
Number of extensions: 1057558
Number of successful extensions: 3388
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 3286
Number of HSP's gapped (non-prelim): 50
length of query: 687
length of database: 18,247,518
effective HSP length: 109
effective length of query: 578
effective length of database: 14,120,124
effective search space: 8161431672
effective search space used: 8161431672
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.